| GOBPID | Pvalue | OddsRatio | ExpCount | Count | Size | Term | Genes |
1 | GO:0045909 | 0.00 | Inf | 5.24 | 14 | 14 | positive regulation of vasodilation | ADM, ADRA2A, ADRB2, AGTR2, ALOX12, CPS1, F2RL1, GJA5, INS, PTAFR, PTPRM, UCN, VIP, KAT2B |
2 | GO:0007188 | 0.00 | Inf | 4.46 | 12 | 12 | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | AVPR2, CCR3, CNR1, FPR1, GCG, GCGR, GNAT1, GNAT2, PRKACB, PTGER4, GLP2R, WASF2 |
3 | GO:0010248 | 0.00 | Inf | 3.74 | 10 | 10 | establishment or maintenance of transmembrane electrochemical gradient | ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP1A4, ATP1B3, FXYD2, ATP4A, BAX, SLC22A1 |
4 | GO:0033762 | 0.00 | Inf | 3.35 | 9 | 9 | response to glucagon | CDO1, CREB1, CRY1, CYC1, HMGCS2, PFKFB1, QDPR, RPS6KB1, SREBF1 |
5 | GO:0071887 | 0.00 | Inf | 2.98 | 8 | 8 | leukocyte apoptotic process | CLC, DFFA, IFNG, IL2RA, RIPK1, BCL2L11, SIVA1, TRAF3IP2 |
6 | GO:1901381 | 0.00 | Inf | 2.99 | 8 | 8 | positive regulation of potassium ion transmembrane transport | DPP6, EDN3, KCNC1, KCNC2, KCNE1, KCNH2, KCNJ2, KCNQ1 |
7 | GO:0003085 | 0.00 | Inf | 2.99 | 8 | 8 | negative regulation of systemic arterial blood pressure | ADRB2, AGTR2, BBS4, BMPR2, NTSR1, PRCP, SOD2, KCNK6 |
8 | GO:0010523 | 0.00 | Inf | 2.99 | 8 | 8 | negative regulation of calcium ion transport into cytosol | BCL2, CALM1, CALM3, CASQ2, GSTM2, NTSR1, GSTO1, TRDN |
9 | GO:0014002 | 0.00 | Inf | 2.99 | 8 | 8 | astrocyte development | CDK6, GFAP, KRAS, S100A8, S100A9, VIM, EIF2B5, TSPAN2 |
10 | GO:0030007 | 0.00 | Inf | 2.99 | 8 | 8 | cellular potassium ion homeostasis | ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP1A4, ATP1B3, ATP4A, KCNJ2 |
11 | GO:0036376 | 0.00 | Inf | 2.99 | 8 | 8 | sodium ion export from cell | ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP1A4, ATP1B3, FXYD2, ATP4A |
12 | GO:0042340 | 0.00 | Inf | 2.99 | 8 | 8 | keratan sulfate catabolic process | GALNS, GLB1, HEXA, HEXB, LUM, OMD, OGN, KERA |
13 | GO:0051284 | 0.00 | Inf | 2.99 | 8 | 8 | positive regulation of sequestering of calcium ion | CALM1, CALM3, CASQ2, GSTM2, NTSR1, RYR2, GSTO1, TRDN |
14 | GO:0051482 | 0.00 | Inf | 2.99 | 8 | 8 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | AGTR1, S1PR1, LPAR1, EDNRA, F2R, GRM1, HTR2C, KISS1 |
15 | GO:0022602 | 0.00 | Inf | 2.61 | 7 | 7 | ovulation cycle process | KISS1, PAM, PGR, SLIT3, NRIP1, SLIT2, ADAMTS1 |
16 | GO:0006105 | 0.00 | Inf | 2.62 | 7 | 7 | succinate metabolic process | GAD1, GAD2, SDHA, SDHB, STAT5B, SUCLG1, SUCLA2 |
17 | GO:0006107 | 0.00 | Inf | 2.62 | 7 | 7 | oxaloacetate metabolic process | ACLY, GOT1, GOT2, MDH1, MDH2, PCK1, STAT5B |
18 | GO:0014819 | 0.00 | Inf | 2.62 | 7 | 7 | regulation of skeletal muscle contraction | ATP2A1, CASQ1, CAV3, GSTM2, KCNJ2, SLC8A3, GSTO1 |
19 | GO:0034616 | 0.00 | Inf | 2.62 | 7 | 7 | response to laminar fluid shear stress | ABCA1, ASS1, ETS1, SMAD6, SMAD7, KLF4, KLF2 |
20 | GO:0035025 | 0.00 | Inf | 2.62 | 7 | 7 | positive regulation of Rho protein signal transduction | APOA1, COL3A1, LPAR1, F2R, F2RL1, RAC1, GPR55 |
21 | GO:0043116 | 0.00 | Inf | 2.62 | 7 | 7 | negative regulation of vascular permeability | ADM, ANGPT1, ARHGAP35, PDE3A, PTPRJ, SLIT2, RAMP2 |
22 | GO:0050667 | 0.00 | Inf | 2.62 | 7 | 7 | homocysteine metabolic process | AHCY, BHMT, CBS, COMT, CPS1, CTH, DPEP1 |
23 | GO:0052548 | 0.00 | Inf | 2.22 | 6 | 6 | regulation of endopeptidase activity | EPHA7, MGMT, PSMA3, SOX2, TP63, KIAA0141 |
24 | GO:0050901 | 0.00 | Inf | 2.24 | 6 | 6 | leukocyte tethering or rolling | ITGB1, SELE, SELP, SELPLG, VCAM1, MADCAM1 |
25 | GO:0000730 | 0.00 | Inf | 2.24 | 6 | 6 | DNA recombinase assembly | RAD51, RAD51C, RAD51B, RAD51D, RAD52, XRCC2 |
26 | GO:0005984 | 0.00 | Inf | 2.24 | 6 | 6 | disaccharide metabolic process | GAA, B4GALT1, IDUA, SLC2A1, MGAM, TREH |
27 | GO:0006782 | 0.00 | Inf | 2.24 | 6 | 6 | protoporphyrinogen IX biosynthetic process | ALAD, ALAS1, ALAS2, CPOX, HMBS, UROS |
28 | GO:0007263 | 0.00 | Inf | 2.24 | 6 | 6 | nitric oxide mediated signal transduction | AGTR2, CD36, FPR1, GUCY1B3, KCNC2, SPINK1 |
29 | GO:0019042 | 0.00 | Inf | 2.24 | 6 | 6 | viral latency | HMGA1, XRCC4, XRCC5, BANF1, CREB3, PSIP1 |
30 | GO:0031284 | 0.00 | Inf | 2.24 | 6 | 6 | positive regulation of guanylate cyclase activity | GUCA1A, GUCA1B, GUCA2A, GUCA2B, RCVRN, GUCA1C |
31 | GO:0032909 | 0.00 | Inf | 2.24 | 6 | 6 | regulation of transforming growth factor beta2 production | CDH3, ATF2, GATA6, HIF1A, SMAD3, WNT11 |
32 | GO:0033623 | 0.00 | Inf | 2.24 | 6 | 6 | regulation of integrin activation | CDH17, PTGER4, SELP, PIEZO1, FARP2, CXCL13 |
33 | GO:0035234 | 0.00 | Inf | 2.24 | 6 | 6 | ectopic germ cell programmed cell death | BAX, CASP5, IL1A, IL1B, KIT, KITLG |
34 | GO:0048664 | 0.00 | Inf | 2.24 | 6 | 6 | neuron fate determination | ATOH1, CDC42, HES1, OTX2, PRRX1, WNT1 |
35 | GO:0051901 | 0.00 | Inf | 2.24 | 6 | 6 | positive regulation of mitochondrial depolarization | ALOX12, TSPO, CCK, DCN, KDR, P2RX7 |
36 | GO:0060315 | 0.00 | Inf | 2.24 | 6 | 6 | negative regulation of ryanodine-sensitive calcium-release channel activity | CALM1, CALM3, CASQ2, GSTM2, GSTO1, TRDN |
37 | GO:0070257 | 0.00 | Inf | 2.24 | 6 | 6 | positive regulation of mucus secretion | CYBA, P2RY2, PRKCE, PTGER4, ATG5, ATG7 |
38 | GO:0071236 | 0.00 | Inf | 2.24 | 6 | 6 | cellular response to antibiotic | HMBS, IL1B, SCN3A, SLC9A1, STAR, RAB10 |
39 | GO:0086016 | 0.00 | Inf | 2.24 | 6 | 6 | AV node cell action potential | CXADR, GJA5, RYR2, SCN4B, SCN5A, SCN10A |
40 | GO:0086067 | 0.00 | Inf | 2.24 | 6 | 6 | AV node cell to bundle of His cell communication | CXADR, GJA5, RYR2, SCN4B, SCN5A, SCN10A |
41 | GO:0098739 | 0.00 | Inf | 2.24 | 6 | 6 | import across plasma membrane | ATP1A1, ATP1A2, FXYD2, SLC2A5, SLC9A1, TRPM2 |
42 | GO:0031960 | 0.01 | Inf | 1.84 | 5 | 5 | response to corticosteroid | COL1A1, CTGF, AKR1C3, AIFM1, SOX30 |
43 | GO:0014706 | 0.01 | Inf | 1.85 | 5 | 5 | striated muscle tissue development | CENPF, EYA1, EYA2, IFRD1, SMAD3 |
44 | GO:0071241 | 0.01 | Inf | 1.86 | 5 | 5 | cellular response to inorganic substance | ATRX, BAD, RAD51, TNFSF4, EIF4A3 |
45 | GO:0010863 | 0.01 | Inf | 1.86 | 5 | 5 | positive regulation of phospholipase C activity | ABL2, ESR1, FLT1, KIT, PTAFR |
46 | GO:0044003 | 0.01 | Inf | 1.86 | 5 | 5 | modification by symbiont of host morphology or physiology | ALB, APCS, ITGAV, SERPINB9, TNIP1 |
47 | GO:0072378 | 0.01 | Inf | 1.87 | 5 | 5 | blood coagulation, fibrin clot formation | F3, F7, FBLN1, FGA, FGG |
48 | GO:0001878 | 0.01 | Inf | 1.87 | 5 | 5 | response to yeast | ANG, APP, CD86, TAC1, VIP |
49 | GO:0006188 | 0.01 | Inf | 1.87 | 5 | 5 | IMP biosynthetic process | ADSL, AMPD1, AMPD2, HPRT1, PFAS |
50 | GO:0009629 | 0.01 | Inf | 1.87 | 5 | 5 | response to gravity | BGLAP, CBLB, PTAFR, SPARC, FOSL1 |
51 | GO:0021561 | 0.01 | Inf | 1.87 | 5 | 5 | facial nerve development | EGR2, SEMA3F, SIX1, NRP1, SEMA3A |
52 | GO:0032060 | 0.01 | Inf | 1.87 | 5 | 5 | bleb assembly | LPAR1, EMP1, EMP2, EMP3, P2RX7 |
53 | GO:0032930 | 0.01 | Inf | 1.87 | 5 | 5 | positive regulation of superoxide anion generation | CRP, CYBA, F2RL1, PRKCD, SOD1 |
54 | GO:0042148 | 0.01 | Inf | 1.87 | 5 | 5 | strand invasion | RAD51, RAD51C, RAD51B, RAD51D, XRCC2 |
55 | GO:0042760 | 0.01 | Inf | 1.87 | 5 | 5 | very long-chain fatty acid catabolic process | ACADVL, ABCD1, ABCD3, SLC27A4, SLC27A2 |
56 | GO:0044539 | 0.01 | Inf | 1.87 | 5 | 5 | long-chain fatty acid import | CD36, ACSL1, ACSL3, SLC27A4, SLC27A2 |
57 | GO:0045792 | 0.01 | Inf | 1.87 | 5 | 5 | negative regulation of cell size | CAV3, PTEN, RDX, TSC1, UCN |
58 | GO:0048050 | 0.01 | Inf | 1.87 | 5 | 5 | post-embryonic eye morphogenesis | BAX, FBN1, EFEMP1, HMGN1, KDR |
59 | GO:0051769 | 0.01 | Inf | 1.87 | 5 | 5 | regulation of nitric-oxide synthase biosynthetic process | FCER2, KDR, PGGT1B, PTGER4, CCL20 |
60 | GO:0051918 | 0.01 | Inf | 1.87 | 5 | 5 | negative regulation of fibrinolysis | APOH, F2, HRG, SERPINE1, USF1 |
61 | GO:0060137 | 0.01 | Inf | 1.87 | 5 | 5 | maternal process involved in parturition | ARNTL, EDNRA, OXTR, PTAFR, PTGER4 |
62 | GO:0060263 | 0.01 | Inf | 1.87 | 5 | 5 | regulation of respiratory burst | APOH, INS, RAC1, RAC2, RPS19 |
63 | GO:0075713 | 0.01 | Inf | 1.87 | 5 | 5 | establishment of integrated proviral latency | HMGA1, XRCC4, XRCC5, BANF1, PSIP1 |
64 | GO:1900376 | 0.01 | Inf | 1.87 | 5 | 5 | regulation of secondary metabolite biosynthetic process | ASIP, CDH3, TYRP1, RAPGEF2, ZEB2 |
65 | GO:1901844 | 0.01 | Inf | 1.87 | 5 | 5 | regulation of cell communication by electrical coupling involved in cardiac conduction | CALM1, CALM3, HRC, PDE4D, TRDN |
66 | GO:1901894 | 0.01 | Inf | 1.87 | 5 | 5 | regulation of calcium-transporting ATPase activity | PLN, RYR2, SLN, SUMO1, RGN |
67 | GO:1902510 | 0.01 | Inf | 1.87 | 5 | 5 | regulation of apoptotic DNA fragmentation | APAF1, BAX, CDKN2A, DFFA, AIFM1 |
68 | GO:1903140 | 0.01 | Inf | 1.87 | 5 | 5 | regulation of establishment of endothelial barrier | S1PR3, IL1B, PROC, TNFRSF1A, S1PR2 |
69 | GO:1903236 | 0.01 | Inf | 1.87 | 5 | 5 | regulation of leukocyte tethering or rolling | ITGA4, PAWR, PTAFR, CCL21, CCL25 |
70 | GO:1903416 | 0.01 | Inf | 1.87 | 5 | 5 | response to glycoside | ATP1A1, ATP1A2, ATP1A3, RAD51, CHEK2 |
71 | GO:1903546 | 0.01 | Inf | 1.87 | 5 | 5 | protein localization to photoreceptor outer segment | BBS4, TUB, TULP1, TULP2, TULP3 |
72 | GO:2000074 | 0.01 | Inf | 1.87 | 5 | 5 | regulation of type B pancreatic cell development | ARNTL, BAD, RFX3, RHEB, CLOCK |
73 | GO:2000271 | 0.01 | Inf | 1.87 | 5 | 5 | positive regulation of fibroblast apoptotic process | BTG1, TP63, STK17B, STK17A, BCL2L11 |
74 | GO:2000310 | 0.01 | Inf | 1.87 | 5 | 5 | regulation of N-methyl-D-aspartate selective glutamate receptor activity | CRH, CRHBP, PTK2B, RELN, NRXN1 |
75 | GO:0033574 | 0.00 | 26.90 | 6.36 | 16 | 17 | response to testosterone | ADRB2, AVP, BAD, BGLAP, BMP4, TSPO, CDK4, DNMT1, DUSP1, ELK1, HMGCS2, KCNJ11, PLN, PSPH, RPS6KB1, SRD5A1 |
76 | GO:0048662 | 0.00 | 25.21 | 5.98 | 15 | 16 | negative regulation of smooth muscle cell proliferation | ANG, COMT, ESR1, IFNG, IGFBP3, IGFBP5, IL12B, IL15, ILK, OGN, TNFAIP3, VIP, VIPR2, KLF4, TRIB1 |
77 | GO:0090281 | 0.00 | 20.15 | 4.86 | 12 | 13 | negative regulation of calcium ion import | CALM1, CALM3, CASQ2, GSTM2, NTSR1, PAWR, PLN, SEMG1, SLN, SPINK1, GSTO1, TRDN |
78 | GO:0050918 | 0.00 | 18.53 | 4.48 | 11 | 12 | positive chemotaxis | ANGPT1, ANGPT2, BMP4, FGF7, HGF, PTPRJ, SAA4, TSC2, NRP1, SEMA5A, CORO1A |
79 | GO:0060350 | 0.00 | 18.51 | 4.48 | 11 | 12 | endochondral bone morphogenesis | BMPR2, SERPINH1, COL9A1, COMP, HOXD11, RARA, RARB, SOX9, STC1, CER1, CARM1 |
80 | GO:0071312 | 0.00 | 18.49 | 4.48 | 11 | 12 | cellular response to alkaloid | BAD, BCL2L1, CRH, CRHBP, ICAM1, KCNJ11, NTRK1, RAD51, SLC34A1, STAR, TRPV1 |
81 | GO:0033189 | 0.00 | 18.47 | 4.49 | 11 | 12 | response to vitamin A | ARG1, CAT, DNMT1, DNMT3B, GATA4, RARA, RXRA, SLC34A1, TSHB, TYMS, ALDH1A2 |
82 | GO:0060334 | 0.00 | 18.47 | 4.49 | 11 | 12 | regulation of interferon-gamma-mediated signaling pathway | HPX, HSP90AB1, IFNG, IFNGR1, PTPN1, PTPN6, STAT1, SUMO1, NR1H2, SOCS3, CDC37 |
83 | GO:0071380 | 0.00 | 18.47 | 4.49 | 11 | 12 | cellular response to prostaglandin E stimulus | ADCY6, GNAS, GNB1, P2RY4, P2RY6, PRKAA1, PRKCE, PTGER2, PTGER4, TNFSF4, ADAMTS1 |
84 | GO:0001954 | 0.00 | 16.82 | 4.11 | 10 | 11 | positive regulation of cell-matrix adhesion | CD36, CDK6, EMP2, EPHA1, PTK2B, ILK, PRKCZ, CCL21, CCL25, VEGFC |
85 | GO:0021602 | 0.00 | 16.78 | 4.11 | 10 | 11 | cranial nerve morphogenesis | PHOX2A, CHRNB2, EGR2, HOXD3, KCNA2, ATP8B1, SEMA3F, SIX1, NRP1, SEMA3A |
86 | GO:0033197 | 0.00 | 16.78 | 4.11 | 10 | 11 | response to vitamin E | ALAD, ARG1, CCND1, CAT, CCNE1, COL1A1, HMGCS1, PAWR, EIF2AK2, BECN1 |
87 | GO:0045086 | 0.00 | 16.78 | 4.11 | 10 | 11 | positive regulation of interleukin-2 biosynthetic process | CD3E, CD4, CD28, CD80, CD86, IL1A, IL1B, PRKCQ, STAT5B, GLMN |
88 | GO:0051000 | 0.00 | 16.78 | 4.11 | 10 | 11 | positive regulation of nitric-oxide synthase activity | AGTR2, CALM1, CALM3, DHFR, ESR1, PTK2B, FCER2, HIF1A, INS, KRAS |
89 | GO:0060055 | 0.00 | 16.78 | 4.11 | 10 | 11 | angiogenesis involved in wound healing | ETS1, B4GALT1, GPX1, SERPINE1, PIK3CB, PRCP, CX3CL1, SRF, TNFAIP3, VEGFB |
90 | GO:0016558 | 0.00 | 15.10 | 3.74 | 9 | 10 | protein import into peroxisome matrix | PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX14, PEX5, PEX16 |
91 | GO:0030049 | 0.00 | 15.10 | 3.74 | 9 | 10 | muscle filament sliding | TMOD1, TNNC2, TNNC1, TNNI2, TNNI3, TNNT1, TNNT2, TPM2, VIM |
92 | GO:0034349 | 0.00 | 15.10 | 3.74 | 9 | 10 | glial cell apoptotic process | APAF1, BAX, BID, CASP9, GAS6, PRKCD, PRKCI, RB1, TRAF2 |
93 | GO:0071257 | 0.00 | 15.10 | 3.74 | 9 | 10 | cellular response to electrical stimulus | ADSS, GNAT1, GRM1, HIF1A, IGF1, PALM, REST, RPE65, SLC9A1 |
94 | GO:0071732 | 0.00 | 15.10 | 3.74 | 9 | 10 | cellular response to nitric oxide | CDK2, DNM2, DPEP1, GUCY1B3, HNRNPD, KCNC2, MAPK8, TRAF2, AIFM1 |
95 | GO:0071941 | 0.00 | 15.10 | 3.74 | 9 | 10 | nitrogen cycle metabolic process | ARG1, ARG2, ASL, ASS1, CPS1, OTC, SUOX, NR1H4, SLC25A15 |
96 | GO:0060416 | 0.00 | 13.46 | 3.36 | 8 | 9 | response to growth hormone | ASS1, CPS1, F7, HMGCS2, IGFBP5, SLC34A1, SRD5A1, TRIM16 |
97 | GO:0050771 | 0.00 | 13.45 | 3.36 | 8 | 9 | negative regulation of axonogenesis | DCC, EPHA7, GDI1, OMG, PSEN1, PTEN, PTK2, ARHGEF1 |
98 | GO:0009642 | 0.00 | 13.42 | 3.37 | 8 | 9 | response to light intensity | CAT, GNAT1, GNAT2, HMGCS1, KCNC1, KCNC2, RS1, SLC24A1 |
99 | GO:0042026 | 0.00 | 13.42 | 3.37 | 8 | 9 | protein refolding | BAG1, DNAJB2, HSPA6, HSPA8, HSP90AA1, SNRNP70, DNAJC7, BAG5 |
100 | GO:0042053 | 0.00 | 13.42 | 3.37 | 8 | 9 | regulation of dopamine metabolic process | ABAT, CHRNB2, COMT, HPRT1, PARK2, PDE1B, SNCA, TACR3 |
101 | GO:0043496 | 0.00 | 13.42 | 3.37 | 8 | 9 | regulation of protein homodimerization activity | BAX, BCL2, NRG1, ISL1, ITGA4, TRAF2, TNFSF18, TRAF4 |
102 | GO:0048532 | 0.00 | 13.42 | 3.37 | 8 | 9 | anatomical structure arrangement | BMPR1A, EGR2, KCNA2, RAC1, SEMA3F, USP9X, NRP1, SEMA3A |
103 | GO:0033002 | 0.00 | 13.24 | 16.42 | 39 | 44 | muscle cell proliferation | ALOX12, ANG, BMP4, COMT, CYBA, HBEGF, S1PR1, EDNRA, EREG, ESR1, FLT1, HIF1A, HMGCR, IFNG, IGF1, IGFBP3, IGFBP5, IL12B, IL13, IL15, ILK, IRAK1, JUN, OGN, ORC1, PTAFR, RPS6KB1, CX3CL1, SHC1, STAT1, STAT5B, TNFAIP3, VIP, VIPR2, XRCC5, KLF4, HDAC4, CALCRL, TRIB1 |
104 | GO:0010107 | 0.00 | 12.91 | 9.72 | 23 | 26 | potassium ion import | ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP1A4, ATP1B3, FXYD2, ATP4A, KCNJ1, KCNJ2, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ12, KCNJ13, KCNJ14, KCNJ16, SLC12A6, KCNE2, ABCC9 |
105 | GO:0051384 | 0.00 | 11.98 | 20.83 | 49 | 56 | response to glucocorticoid | ABCA3, ACADS, ADM, AGXT, ALAD, ALDH3A1, ALDOB, ANXA3, AREG, BAD, BCHE, BCL2, BGLAP, BMP4, BMP6, C3, CALCR, CDO1, CTSV, DUSP1, GHRHR, GOT1, HIF1A, HNMT, IGF1, IGFBP2, IL1RN, IL10, KRAS, LCAT, LIPC, PAM, PFKFB1, RPS6KB1, RXRA, S100B, SHC1, SLC9A3, SLIT3, SPARC, TAT, TYMS, UCN, SCGB1A1, ADAM9, SOCS3, SLIT2, PDCD7, GPR83 |
106 | GO:0008306 | 0.00 | 11.82 | 5.97 | 14 | 16 | associative learning | ADCY3, ADRB2, CRH, DRD5, GABRA5, RELN, SNAP25, SRF, TAC1, TNR, UCN, RIN1, EIF4A3, TBR1 |
107 | GO:0035924 | 0.01 | 11.77 | 2.99 | 7 | 8 | cellular response to vascular endothelial growth factor stimulus | EGR3, ERN1, GAS1, NR4A1, VCAM1, ITGB1BP1, RAMP2 |
108 | GO:0050999 | 0.01 | 11.77 | 2.99 | 7 | 8 | regulation of nitric-oxide synthase activity | ACVR2A, CAV3, CNR1, CNR2, DNM2, HSP90AA1, IL1B |
109 | GO:0098801 | 0.01 | 11.77 | 2.99 | 7 | 8 | regulation of renal system process | CYBA, EMP2, F2R, F2RL1, GAS6, GJA5, STC1 |
110 | GO:0006099 | 0.00 | 11.76 | 5.98 | 14 | 16 | tricarboxylic acid cycle | ACO1, ACO2, IDH1, IDH3A, MDH1, MDH2, OGDH, SDHA, SDHB, SDHC, SDHD, SUCLG2, SUCLG1, SUCLA2 |
111 | GO:0086004 | 0.00 | 11.76 | 5.98 | 14 | 16 | regulation of cardiac muscle cell contraction | ATP1A1, ATP1A2, DSC2, DSP, GATA4, GJA5, KCNJ2, PDE4B, PDE4D, PLN, RYR2, SCN5A, STC1, SUMO1 |
112 | GO:0000050 | 0.01 | 11.74 | 2.99 | 7 | 8 | urea cycle | ARG1, ARG2, ASL, ASS1, CPS1, OTC, SLC25A15 |
113 | GO:0001774 | 0.01 | 11.74 | 2.99 | 7 | 8 | microglial cell activation | CLU, CX3CR1, IL13, JUN, CX3CL1, SNCA, TRPV1 |
114 | GO:0003417 | 0.01 | 11.74 | 2.99 | 7 | 8 | growth plate cartilage development | COL9A1, COMP, RARA, RARB, STC1, CER1, CARM1 |
115 | GO:0009071 | 0.01 | 11.74 | 2.99 | 7 | 8 | serine family amino acid catabolic process | AGXT, AMT, CBS, CDO1, GLDC, SHMT1, SDS |
116 | GO:0010224 | 0.01 | 11.74 | 2.99 | 7 | 8 | response to UV-B | BCL2, CDKN1A, ERCC6, HMGN1, IL12B, STK11, XPC |
117 | GO:0019852 | 0.01 | 11.74 | 2.99 | 7 | 8 | L-ascorbic acid metabolic process | CYB5A, CYB5R3, SLC2A1, SLC2A3, RGN, GSTO1, AKR1A1 |
118 | GO:0035404 | 0.01 | 11.74 | 2.99 | 7 | 8 | histone-serine phosphorylation | CCNB1, PRKAA1, AURKA, VRK1, HMGA2, RPS6KA4, AURKB |
119 | GO:0035864 | 0.01 | 11.74 | 2.99 | 7 | 8 | response to potassium ion | CLU, CRHBP, CYP11B1, KCNC1, KCNJ1, SLC34A1, SOD1 |
120 | GO:0042448 | 0.01 | 11.74 | 2.99 | 7 | 8 | progesterone metabolic process | ADM, FSHB, SRD5A1, STAR, STAT5B, AKR1C3, DHRS9 |
121 | GO:0045821 | 0.01 | 11.74 | 2.99 | 7 | 8 | positive regulation of glycolytic process | ARNT, GPD1, HIF1A, IGF1, INS, P2RX7, PRKAA1 |
122 | GO:0051194 | 0.01 | 11.74 | 2.99 | 7 | 8 | positive regulation of cofactor metabolic process | ARNT, GPD1, HIF1A, IGF1, INS, P2RX7, PRKAA1 |
123 | GO:0055093 | 0.01 | 11.74 | 2.99 | 7 | 8 | response to hyperoxia | BNIP3, CAT, CDK4, CDKN1A, COL1A1, DNMT3B, ATG7 |
124 | GO:0070493 | 0.01 | 11.74 | 2.99 | 7 | 8 | thrombin receptor signaling pathway | DGKQ, F2R, F2RL1, F2RL2, GP1BA, HPGD, SNCA |
125 | GO:0090201 | 0.01 | 11.74 | 2.99 | 7 | 8 | negative regulation of release of cytochrome c from mitochondria | AVP, BCL2L1, GPX1, HGF, IGF1, OPA1, PARK2 |
126 | GO:2000811 | 0.01 | 11.74 | 2.99 | 7 | 8 | negative regulation of anoikis | BCL2, BCL2L1, ITGA5, ITGB1, NTRK2, PDK4, PTK2 |
127 | GO:0009187 | 0.00 | 11.08 | 5.56 | 13 | 15 | cyclic nucleotide metabolic process | ATP2B2, CACNB4, CNP, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE7A, PDE8A, PDE1B, PDE10A, NUDT4 |
128 | GO:0043278 | 0.00 | 10.92 | 5.61 | 13 | 15 | response to morphine | ADRA1B, CNR1, DRD3, EDNRA, FGA, IL1B, PENK, PPP2R2A, PPP5C, PRKCE, TAC1, TACR3, PEA15 |
129 | GO:0070848 | 0.00 | 10.73 | 5.03 | 12 | 14 | response to growth factor | ANXA3, ASCL1, EPHA2, IL1R1, KCNC1, KCNC2, LUM, P2RY1, P2RY2, SOX2, SCGB1A1, HDAC6 |
130 | GO:0035094 | 0.00 | 10.65 | 8.23 | 19 | 22 | response to nicotine | ABAT, ATP1A2, AVP, BAD, BCL2, CHRNB2, CHRNB4, CNR1, CREB1, IGF1, IGF2, IL13, KCNJ11, NTRK1, PENK, SHC1, STAR, VCAM1, RAPGEF3 |
131 | GO:0072350 | 0.00 | 10.65 | 8.23 | 19 | 22 | tricarboxylic acid metabolic process | ACLY, ACO1, ACO2, ASS1, GLUD1, IDH1, IDH3A, MDH1, MDH2, OGDH, SDHA, SDHB, SDHC, SDHD, SLC34A1, STAT5B, SUCLG2, SUCLG1, SUCLA2 |
132 | GO:0010038 | 0.01 | 10.36 | 2.57 | 6 | 7 | response to metal ion | ASCL1, ATP12A, HMGCS2, IGFBP2, TNNC1, KEAP1 |
133 | GO:1901654 | 0.01 | 10.24 | 2.59 | 6 | 7 | response to ketone | F7, HNRNPD, CCL21, SLIT3, SLIT2, CHEK2 |
134 | GO:0046394 | 0.01 | 10.20 | 2.59 | 6 | 7 | carboxylic acid biosynthetic process | UGDH, UGP2, UROS, SUCLA2, GSTO1, AKR1A1 |
135 | GO:0006813 | 0.01 | 10.17 | 2.60 | 6 | 7 | potassium ion transport | ATP4B, CDK2, GJA5, SLC12A1, SLC12A2, TSC1 |
136 | GO:0051444 | 0.01 | 10.13 | 2.61 | 6 | 7 | negative regulation of ubiquitin-protein transferase activity | ABL1, CDKN2A, LIMK1, SMAD7, PSEN1, BAG5 |
137 | GO:0021536 | 0.01 | 10.12 | 2.61 | 6 | 7 | diencephalon development | KCNC1, KCNC2, OTX1, OTX2, WNT1, SEMA5A |
138 | GO:0045907 | 0.00 | 10.09 | 7.85 | 18 | 21 | positive regulation of vasoconstriction | ADRA1B, AVP, AVPR1B, AVPR2, CD38, DBH, F2R, FGA, FGG, GJA5, UTS2R, HRH1, HRH2, ICAM1, OXTR, PTAFR, PTGS1, SHC1 |
139 | GO:0014009 | 0.01 | 10.08 | 2.61 | 6 | 7 | glial cell proliferation | AREG, CLU, CREB1, EEF2, PTK2B, PENK |
140 | GO:0010092 | 0.01 | 10.08 | 2.62 | 6 | 7 | specification of organ identity | RBPJ, ISL1, PAX3, SMARCD3, PAX8, TBR1 |
141 | GO:0034698 | 0.00 | 10.07 | 5.24 | 12 | 14 | response to gonadotropin | CTSV, GATA4, GATA6, HMGCS1, ICAM1, ITGA3, ITGB1, PAWR, SLC5A5, SRD5A1, STAR, PAX8 |
142 | GO:0030194 | 0.01 | 10.07 | 2.62 | 6 | 7 | positive regulation of blood coagulation | CD36, F2R, F3, F7, S100A9, SELP |
143 | GO:0031000 | 0.01 | 10.07 | 2.62 | 6 | 7 | response to caffeine | DNMT1, DNMT3B, GNAL, IGF1, PRKAA1, SDC2 |
144 | GO:0033028 | 0.01 | 10.07 | 2.62 | 6 | 7 | myeloid cell apoptotic process | ANXA1, ARF6, CDKN2A, IFNG, PTEN, ADAM17 |
145 | GO:0001553 | 0.01 | 10.06 | 2.62 | 6 | 7 | luteinization | CAPN5, NR5A1, GDF9, PTPRN, STAT5B, FZD4 |
146 | GO:0002726 | 0.01 | 10.06 | 2.62 | 6 | 7 | positive regulation of T cell cytokine production | PRKCZ, XCL1, TRAF2, TNFSF4, FZD5, MALT1 |
147 | GO:0006538 | 0.01 | 10.06 | 2.62 | 6 | 7 | glutamate catabolic process | GAD1, GAD2, GLUD1, GLUL, GOT1, GOT2 |
148 | GO:0007350 | 0.01 | 10.06 | 2.62 | 6 | 7 | blastoderm segmentation | HOXD8, PCSK6, SEMA3F, FZD5, NRP1, SEMA3A |
149 | GO:0010560 | 0.01 | 10.06 | 2.62 | 6 | 7 | positive regulation of glycoprotein biosynthetic process | GOLGA2, IGF1, IL15, PAWR, CCL21, ARFGEF1 |
150 | GO:0014051 | 0.01 | 10.06 | 2.62 | 6 | 7 | gamma-aminobutyric acid secretion | ABAT, CACNA1A, CACNB4, NTSR1, P2RX7, TRPC4 |
151 | GO:0014854 | 0.01 | 10.06 | 2.62 | 6 | 7 | response to inactivity | CASQ1, CAT, F2, IL10, SCN5A, HDAC4 |
152 | GO:0015810 | 0.01 | 10.06 | 2.62 | 6 | 7 | aspartate transport | ABAT, NTSR1, SLC1A3, SLC1A6, SLC25A12, SLC25A13 |
153 | GO:0019740 | 0.01 | 10.06 | 2.62 | 6 | 7 | nitrogen utilization | BAX, BCL2, RHAG, RHCE, RHD, NR1H4 |
154 | GO:0021548 | 0.01 | 10.06 | 2.62 | 6 | 7 | pons development | PHOX2A, ASCL1, BCL2, CACNA1A, SLC4A7, SEC24B |
155 | GO:0022401 | 0.01 | 10.06 | 2.62 | 6 | 7 | negative adaptation of signaling pathway | ADM, ADRB2, DNM1, DNM2, DRD3, GRK6 |
156 | GO:0030214 | 0.01 | 10.06 | 2.62 | 6 | 7 | hyaluronan catabolic process | CD44, GUSB, HEXA, HEXB, HMMR, SLC9A1 |
157 | GO:0031645 | 0.01 | 10.06 | 2.62 | 6 | 7 | negative regulation of neurological system process | AVP, GLRA1, IFNG, PTEN, EIF2AK3, FIG4 |
158 | GO:0033131 | 0.01 | 10.06 | 2.62 | 6 | 7 | regulation of glucokinase activity | BAD, FOXA2, PARK2, PFKFB1, PFKFB2, RANBP2 |
159 | GO:0033631 | 0.01 | 10.06 | 2.62 | 6 | 7 | cell-cell adhesion mediated by integrin | DPP4, ITGA5, ITGB1, ADAM9, PIEZO1, CXCL13 |
160 | GO:0045589 | 0.01 | 10.06 | 2.62 | 6 | 7 | regulation of regulatory T cell differentiation | CD28, CTLA4, IFNG, IRF1, CD46, TNFSF4 |
161 | GO:0051593 | 0.01 | 10.06 | 2.62 | 6 | 7 | response to folic acid | ASCL1, BCHE, EEF2, MGMT, OGG1, TYMS |
162 | GO:0051597 | 0.01 | 10.06 | 2.62 | 6 | 7 | response to methylmercury | ALAD, ARG1, CCNE1, CPOX, HMBS, S100B |
163 | GO:0060045 | 0.01 | 10.06 | 2.62 | 6 | 7 | positive regulation of cardiac muscle cell proliferation | CCNB1, GATA4, GATA6, NRG1, RBPJ, WNT2 |
164 | GO:0060134 | 0.01 | 10.06 | 2.62 | 6 | 7 | prepulse inhibition | CTNNA2, DRD3, FABP7, GRID2, PTEN, NRXN1 |
165 | GO:0060253 | 0.01 | 10.06 | 2.62 | 6 | 7 | negative regulation of glial cell proliferation | ASCL2, TSPO, HES1, PTN, SOX11, RNF10 |
166 | GO:0060316 | 0.01 | 10.06 | 2.62 | 6 | 7 | positive regulation of ryanodine-sensitive calcium-release channel activity | CALM1, CALM3, GSTM2, GSTO1, AKAP6, TRDN |
167 | GO:0060442 | 0.01 | 10.06 | 2.62 | 6 | 7 | branching involved in prostate gland morphogenesis | BMP4, CD44, ESR1, IGF1, RXRA, FEM1B |
168 | GO:0061549 | 0.01 | 10.06 | 2.62 | 6 | 7 | sympathetic ganglion development | ASCL1, SEMA3F, NRP2, NRP1, PHOX2B, SEMA3A |
169 | GO:0090344 | 0.01 | 10.06 | 2.62 | 6 | 7 | negative regulation of cell aging | ABL1, CDK6, PTEN, TWIST1, WNT1, TP63 |
170 | GO:0097067 | 0.01 | 10.06 | 2.62 | 6 | 7 | cellular response to thyroid hormone stimulus | BMP4, KLF9, CTSH, KIT, RDX, GAS2L1 |
171 | GO:1901077 | 0.01 | 10.06 | 2.62 | 6 | 7 | regulation of relaxation of muscle | HRC, PAWR, PDE4B, PDE4D, PLN, SLN |
172 | GO:1902260 | 0.01 | 10.06 | 2.62 | 6 | 7 | negative regulation of delayed rectifier potassium channel activity | KCNE1, KCNQ1, SUMO1, KCNAB1, KCNE2, KCNE3 |
173 | GO:0051591 | 0.00 | 9.84 | 12.67 | 29 | 34 | response to cAMP | AGXT, ALDH3A1, ALDOB, BIRC2, AREG, ATP7B, BSG, CDK2, CDO1, COL1A1, DUSP1, PTK2B, HMGCS2, JUN, JUND, LDHA, CITED1, PAX4, PDE3A, PER1, PFKFB1, PTPRN, PYGM, SPARC, SREBF1, STAT1, TYR, FOSL1, CARM1 |
174 | GO:0019228 | 0.00 | 9.53 | 7.48 | 17 | 20 | neuronal action potential | DPP6, IFNG, KCNA1, KCNA2, KCND2, P2RX1, P2RX3, P2RX4, PAWR, SCN1A, SCN2A, SCN3A, SCN5A, SCN7A, SCN8A, SCN10A, KCNMB2 |
175 | GO:0045429 | 0.00 | 9.53 | 7.48 | 17 | 20 | positive regulation of nitric oxide biosynthetic process | AGTR2, AKT2, ASS1, CLU, DNM2, ESR1, PTK2B, HSP90AA1, HSP90AB1, ICAM1, IFNG, IL1B, INS, P2RX4, TRPV1, KLF4, KLF2 |
176 | GO:0042311 | 0.00 | 9.29 | 4.84 | 11 | 13 | vasodilation | BBS2, BDKRB2, GPX1, ITGA1, KCNJ8, KNG1, P2RX4, RGS2, SOD1, SOD2, ATG5 |
177 | GO:0048661 | 0.00 | 9.26 | 9.72 | 22 | 26 | positive regulation of smooth muscle cell proliferation | ALOX12, BMP4, CYBA, HBEGF, S1PR1, EREG, FLT1, HIF1A, HMGCR, IGF1, IL13, IRAK1, JUN, ORC1, PTAFR, RPS6KB1, CX3CL1, SHC1, STAT1, STAT5B, HDAC4, CALCRL |
178 | GO:0006198 | 0.00 | 9.23 | 4.86 | 11 | 13 | cAMP catabolic process | PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, RAPGEF3, PDE10A |
179 | GO:0007214 | 0.00 | 9.23 | 4.86 | 11 | 13 | gamma-aminobutyric acid signaling pathway | ATF4, CACNA1A, CACNB4, GABRA4, GABRA5, GABRA6, GABRE, GABRG1, GABRR1, GABRR2, GABBR2 |
180 | GO:0031290 | 0.00 | 9.23 | 4.86 | 11 | 13 | retinal ganglion cell axon guidance | EFNA5, EPHA7, EPHB1, EPHB3, ISL1, NRCAM, PTPRM, RPL24, NRP1, SLIT2, SEMA4F |
181 | GO:0043574 | 0.00 | 9.23 | 4.86 | 11 | 13 | peroxisomal transport | ABCD1, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX14, PEX19, PEX5, PEX16 |
182 | GO:0055119 | 0.00 | 9.23 | 4.86 | 11 | 13 | relaxation of cardiac muscle | ATP1A1, ATP1A2, GSTM2, HRC, KCNJ2, P2RX4, PDE4B, PDE4D, PLN, RGS2, PDE5A |
183 | GO:1903170 | 0.00 | 9.23 | 4.86 | 11 | 13 | negative regulation of calcium ion transmembrane transport | ADRA2A, ATP1A2, CALM1, CALM3, CASQ2, GSTM2, NTSR1, PLN, SLN, GSTO1, TRDN |
184 | GO:0032570 | 0.00 | 8.96 | 7.11 | 16 | 19 | response to progesterone | ADRB2, BAD, TSPO, C3, CCNE1, CD38, OXTR, PTGER2, PTGER4, PTN, SREBF1, TYMS, FOSL1, SOCS3, RAMP2, TXNIP |
185 | GO:0034694 | 0.00 | 8.96 | 7.11 | 16 | 19 | response to prostaglandin | ADCY6, GNAS, GNB1, HMGCS2, P2RY4, P2RY6, PRKAA1, PRKCE, PTGDR, PTGER2, PTGER4, CCL21, TNFSF4, YY1, AKR1C3, ADAMTS1 |
186 | GO:0072001 | 0.03 | 8.48 | 2.23 | 5 | 6 | renal system development | EMX2, ITGB4, TP63, IFT140, SEC63 |
187 | GO:0043122 | 0.03 | 8.46 | 2.23 | 5 | 6 | regulation of I-kappaB kinase/NF-kappaB signaling | ANGPT1, BCL3, HSPB1, PRDX1, CPNE1 |
188 | GO:0070542 | 0.00 | 8.45 | 4.47 | 10 | 12 | response to fatty acid | ALAD, BAD, CAT, CD36, CTGF, ACSL1, FFAR1, HMGCL, LIPC, PTGS1 |
189 | GO:1903428 | 0.03 | 8.42 | 2.24 | 5 | 6 | positive regulation of reactive oxygen species biosynthetic process | CLCN3, CYBA, RAB27A, OGT, HDAC4 |
190 | GO:0090303 | 0.00 | 8.42 | 4.48 | 10 | 12 | positive regulation of wound healing | ADRA2A, ANXA1, HBEGF, INSL3, PRKCE, PTGER4, RREB1, VEGFB, VTN, ARFGEF1 |
191 | GO:0042089 | 0.03 | 8.42 | 2.24 | 5 | 6 | cytokine biosynthetic process | CEBPE, IL1RAP, IL18, PAWR, PCSK5 |
192 | GO:0019048 | 0.03 | 8.41 | 2.24 | 5 | 6 | modulation by virus of host morphology or physiology | FBLN1, SMAD3, RXRA, TYMS, RRAGA |
193 | GO:0001974 | 0.00 | 8.41 | 6.73 | 15 | 18 | blood vessel remodeling | ACVR2B, ACVRL1, ADRA1B, JAG1, AGTR2, AXL, BAX, BMPR2, DBH, ACE, IGF1, RBPJ, ITGA4, CSRP3, ATG5 |
194 | GO:0010165 | 0.00 | 8.40 | 6.73 | 15 | 18 | response to X-ray | ANXA1, CCND1, BRCA2, CDKN1A, DNM2, ERCC1, ERCC6, HIF1A, RAD51, TP73, XRCC2, XRCC4, XRCC5, HMGA2, TP63 |
195 | GO:0014808 | 0.00 | 8.40 | 6.73 | 15 | 18 | release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | ATP1A2, CALM1, CALM3, CASQ1, CASQ2, CCR5, GSTM2, HRC, PDE4D, PLN, RYR1, RYR2, GSTO1, AKAP6, TRDN |
196 | GO:0045744 | 0.00 | 8.40 | 6.73 | 15 | 18 | negative regulation of G-protein coupled receptor protein signaling pathway | ADM, ADRA2A, ADRB2, BICD1, CRY1, DNM1, DNM2, DRD3, GRK6, PALM, RGS2, RGS12, RGS13, SNCA, GPRASP1 |
197 | GO:0002455 | 0.03 | 8.40 | 2.24 | 5 | 6 | humoral immune response mediated by circulating immunoglobulin | BCL3, FCER2, HPX, PTPN6, EXO1 |
198 | GO:0006182 | 0.03 | 8.39 | 2.24 | 5 | 6 | cGMP biosynthetic process | GUCY1B3, GUCY2C, GUCY2F, GUCY2D, HTR2C |
199 | GO:0035455 | 0.00 | 8.39 | 4.49 | 10 | 12 | response to interferon-alpha | ADAR, AXL, BST2, ENTPD2, GAS6, IFIT3, EIF2AK2, STAR, IFITM3, IFITM2 |
200 | GO:0042136 | 0.00 | 8.39 | 4.49 | 10 | 12 | neurotransmitter biosynthetic process | ACHE, ALDH2, ALDH9A1, DAGLA, CHAT, COMT, GAD1, GAD2, PAH, SLC22A2 |
201 | GO:0060765 | 0.00 | 8.39 | 4.49 | 10 | 12 | regulation of androgen receptor signaling pathway | DAB2, DDX5, EP300, PRMT2, IGF1, RNF6, SMARCA4, BUD31, RNF14, HDAC6 |
202 | GO:0071636 | 0.00 | 8.39 | 4.49 | 10 | 12 | positive regulation of transforming growth factor beta production | CREB1, ATF2, LUM, SMAD3, CD46, XCL1, CX3CL1, WNT11, SERPINB7, ATP6AP2 |
203 | GO:0072663 | 0.00 | 8.39 | 4.49 | 10 | 12 | establishment of protein localization to peroxisome | PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX14, PEX19, PEX5, PEX16 |
204 | GO:0009303 | 0.03 | 8.39 | 2.24 | 5 | 6 | rRNA transcription | ANG, GTF3A, BRF1, SMARCA4, TAF1B |
205 | GO:0042438 | 0.03 | 8.39 | 2.24 | 5 | 6 | melanin biosynthetic process | CTNS, CITED1, TRPC1, TYR, RAPGEF2 |
206 | GO:0001547 | 0.03 | 8.38 | 2.24 | 5 | 6 | antral ovarian follicle growth | CCNE1, CHAT, EREG, ESR1, PTGER4 |
207 | GO:0002551 | 0.03 | 8.38 | 2.24 | 5 | 6 | mast cell chemotaxis | KIT, RAC1, RAC2, VEGFB, VEGFC |
208 | GO:0002862 | 0.03 | 8.38 | 2.24 | 5 | 6 | negative regulation of inflammatory response to antigenic stimulus | GPX1, IL10, IL12B, PSMB4, SPN |
209 | GO:0003161 | 0.03 | 8.38 | 2.24 | 5 | 6 | cardiac conduction system development | CDC42, GJA5, NRG1, MAML1, BVES |
210 | GO:0006559 | 0.03 | 8.38 | 2.24 | 5 | 6 | L-phenylalanine catabolic process | CCBL1, GSTZ1, PAH, QDPR, TAT |
211 | GO:0006704 | 0.03 | 8.38 | 2.24 | 5 | 6 | glucocorticoid biosynthetic process | ATP1A1, CRH, CYP11B1, HSD11B1, REST |
212 | GO:0006975 | 0.03 | 8.38 | 2.24 | 5 | 6 | DNA damage induced protein phosphorylation | ABL1, ATM, CHEK1, CRY1, CHEK2 |
213 | GO:0007158 | 0.03 | 8.38 | 2.24 | 5 | 6 | neuron cell-cell adhesion | ASTN1, TNR, NRXN3, NRXN1, NRXN2 |
214 | GO:0007183 | 0.03 | 8.38 | 2.24 | 5 | 6 | SMAD protein complex assembly | SMAD1, SMAD3, SMAD6, PPM1A, ZFYVE9 |
215 | GO:0009221 | 0.03 | 8.38 | 2.24 | 5 | 6 | pyrimidine deoxyribonucleotide biosynthetic process | DTYMK, DUT, SHMT1, TYMS, TBPL1 |
216 | GO:0015886 | 0.03 | 8.38 | 2.24 | 5 | 6 | heme transport | ABCB7, HPX, HRG, ABCG2, ABCB6 |
217 | GO:0018119 | 0.03 | 8.38 | 2.24 | 5 | 6 | peptidyl-cysteine S-nitrosylation | ADH5, ACE, GAPDH, S100A8, S100A9 |
218 | GO:0019732 | 0.03 | 8.38 | 2.24 | 5 | 6 | antifungal humoral response | ANG, APP, LTF, TAC1, VIP |
219 | GO:0022010 | 0.03 | 8.38 | 2.24 | 5 | 6 | central nervous system myelination | CLU, FGFR3, KCNJ10, PTEN, CNTN2 |
220 | GO:0022027 | 0.03 | 8.38 | 2.24 | 5 | 6 | interkinetic nuclear migration | HHEX, PCM1, TACC1, TACC3, TACC2 |
221 | GO:0022615 | 0.03 | 8.38 | 2.24 | 5 | 6 | protein to membrane docking | PEX13, PEX5, STXBP3, RAB7A, PEX16 |
222 | GO:0032057 | 0.03 | 8.38 | 2.24 | 5 | 6 | negative regulation of translational initiation in response to stress | ATF4, EIF2S1, EIF2B3, EIF2B5, EIF2AK3 |
223 | GO:0032099 | 0.03 | 8.38 | 2.24 | 5 | 6 | negative regulation of appetite | BBS2, BBS4, CCK, GCG, UCN |
224 | GO:0032650 | 0.03 | 8.38 | 2.24 | 5 | 6 | regulation of interleukin-1 alpha production | CASP1, ISL1, P2RX7, PTGER4, CCL20 |
225 | GO:0032769 | 0.03 | 8.38 | 2.24 | 5 | 6 | negative regulation of monooxygenase activity | CAV3, CNR1, CNR2, GFI1, SNCA |
226 | GO:0033033 | 0.03 | 8.38 | 2.24 | 5 | 6 | negative regulation of myeloid cell apoptotic process | APOH, BCL2, FCER1G, KITLG, ST6GAL1 |
227 | GO:0035584 | 0.03 | 8.38 | 2.24 | 5 | 6 | calcium-mediated signaling using intracellular calcium source | KDR, NTRK2, RYR2, SELP, VCAM1 |
228 | GO:0035641 | 0.03 | 8.38 | 2.24 | 5 | 6 | locomotory exploration behavior | CRH, DPP4, PENK, PRKCE, TNR |
229 | GO:0038180 | 0.03 | 8.38 | 2.24 | 5 | 6 | nerve growth factor signaling pathway | RAPGEF1, NTRK1, SORT1, RAPGEF2, CORO1A |
230 | GO:0042178 | 0.03 | 8.38 | 2.24 | 5 | 6 | xenobiotic catabolic process | CRYZ, ACSL1, GSTM1, GSTM2, GSTO1 |
231 | GO:0042320 | 0.03 | 8.38 | 2.24 | 5 | 6 | regulation of circadian sleep/wake cycle, REM sleep | CHRNB2, CRH, GHRH, UTS2R, PTGER4 |
232 | GO:0042447 | 0.03 | 8.38 | 2.24 | 5 | 6 | hormone catabolic process | ACE, DIO3, IDE, UGT2B4, HSD17B6 |
233 | GO:0042711 | 0.03 | 8.38 | 2.24 | 5 | 6 | maternal behavior | AVP, DBH, GNAQ, OXTR, PTEN |
234 | GO:0042791 | 0.03 | 8.38 | 2.24 | 5 | 6 | 5S class rRNA transcription from RNA polymerase III type 1 promoter | GTF3C1, GTF3C2, GTF3C5, GTF3C4, GTF3C3 |
235 | GO:0042797 | 0.03 | 8.38 | 2.24 | 5 | 6 | tRNA transcription from RNA polymerase III promoter | GTF3C1, GTF3C2, GTF3C5, GTF3C4, GTF3C3 |
236 | GO:0044126 | 0.03 | 8.38 | 2.24 | 5 | 6 | regulation of growth of symbiont in host | CD36, IFNG, IL10, IL12B, OSBP |
237 | GO:0044144 | 0.03 | 8.38 | 2.24 | 5 | 6 | modulation of growth of symbiont involved in interaction with host | CD36, IFNG, IL10, IL12B, OSBP |
238 | GO:0045759 | 0.03 | 8.38 | 2.24 | 5 | 6 | negative regulation of action potential | CAV3, CHRNB2, CNR1, CNR2, SUMO1 |
239 | GO:0045938 | 0.03 | 8.38 | 2.24 | 5 | 6 | positive regulation of circadian sleep/wake cycle, sleep | ALB, GHRH, GHRHR, UTS2R, PTGER4 |
240 | GO:0046719 | 0.03 | 8.38 | 2.24 | 5 | 6 | regulation by virus of viral protein levels in host cell | IFIT1, STAT1, STAU1, DYNLT1, VAPB |
241 | GO:0051712 | 0.03 | 8.38 | 2.24 | 5 | 6 | positive regulation of killing of cells of other organism | BAD, F2RL1, FCER2, IFNG, BCL2L11 |
242 | GO:0060158 | 0.03 | 8.38 | 2.24 | 5 | 6 | phospholipase C-activating dopamine receptor signaling pathway | DRD5, GNA15, GNAQ, SLC9A3R1, GNA14 |
243 | GO:0060281 | 0.03 | 8.38 | 2.24 | 5 | 6 | regulation of oocyte development | IGF1, PDE3A, PPP2R1A, AURKA, PDE5A |
244 | GO:0060453 | 0.03 | 8.38 | 2.24 | 5 | 6 | regulation of gastric acid secretion | KCNQ1, OXTR, SGK1, UCN, TRPV1 |
245 | GO:0070886 | 0.03 | 8.38 | 2.24 | 5 | 6 | positive regulation of calcineurin-NFAT signaling cascade | NRG1, IGF1, SLC9A1, SLC12A1, AKAP6 |
246 | GO:0071276 | 0.03 | 8.38 | 2.24 | 5 | 6 | cellular response to cadmium ion | OGG1, PPP5C, SOD1, STAR, AKR1C3 |
247 | GO:0071294 | 0.03 | 8.38 | 2.24 | 5 | 6 | cellular response to zinc ion | TSPO, CREB1, GLRA1, GLRA2, KCNK3 |
248 | GO:0071313 | 0.03 | 8.38 | 2.24 | 5 | 6 | cellular response to caffeine | CASQ2, GSTM2, RYR1, RYR2, RYR3 |
249 | GO:0071374 | 0.03 | 8.38 | 2.24 | 5 | 6 | cellular response to parathyroid hormone stimulus | SLC34A1, FGF23, KAT2B, ADAMTS1, HDAC4 |
250 | GO:0071801 | 0.03 | 8.38 | 2.24 | 5 | 6 | regulation of podosome assembly | BLK, HCK, MAPK8, FSCN1, ARHGEF5 |
251 | GO:0072217 | 0.03 | 8.38 | 2.24 | 5 | 6 | negative regulation of metanephros development | BMP4, CITED1, SALL1, STAT1, PAX8 |
252 | GO:0072498 | 0.03 | 8.38 | 2.24 | 5 | 6 | embryonic skeletal joint development | BMP4, EXT1, HOXC11, HOXD11, IHH |
253 | GO:0086013 | 0.03 | 8.38 | 2.24 | 5 | 6 | membrane repolarization during cardiac muscle cell action potential | ATP1A1, KCNE1, KCNH2, KCNJ2, KCNQ1 |
254 | GO:1902221 | 0.03 | 8.38 | 2.24 | 5 | 6 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process | CCBL1, GSTZ1, PAH, QDPR, TAT |
255 | GO:1903551 | 0.03 | 8.38 | 2.24 | 5 | 6 | regulation of extracellular exosome assembly | SDC4, SDCBP, TSG101, STAM, PDCD6IP |
256 | GO:2000020 | 0.03 | 8.38 | 2.24 | 5 | 6 | positive regulation of male gonad development | NR5A1, SOX9, SRY, CITED2, SEMA3A |
257 | GO:2000323 | 0.03 | 8.38 | 2.24 | 5 | 6 | negative regulation of glucocorticoid receptor signaling pathway | ARNTL, CRY1, CRY2, PER1, CLOCK |
258 | GO:2000794 | 0.03 | 8.38 | 2.24 | 5 | 6 | regulation of epithelial cell proliferation involved in lung morphogenesis | CDC42, FGF7, SRSF6, SOX9, WNT2 |
259 | GO:0014068 | 0.00 | 8.15 | 13.09 | 29 | 35 | positive regulation of phosphatidylinositol 3-kinase signaling | ANGPT1, CAT, CBL, CD28, DCN, F2, F2R, F2RL1, FGR, FLT1, FLT3, FSHR, FYN, HCLS1, HGF, NRG1, IGF1, INS, KDR, KIT, NTRK2, RELN, PTK2, PTPN6, SELP, SOX9, UBE3A, BECN1, SEMA4D |
260 | GO:0043525 | 0.00 | 7.99 | 8.60 | 19 | 23 | positive regulation of neuron apoptotic process | ASCL1, ATF4, ATM, BAX, CASP9, CDC42, ATF2, DDIT3, EPHA7, FGFR3, ITGA1, JUN, MAP3K11, PARK2, PAWR, SRPK2, AIFM1, HDAC4, BCL2L11 |
261 | GO:0030819 | 0.00 | 7.96 | 14.96 | 33 | 40 | positive regulation of cAMP biosynthetic process | ABCA1, ADM, ADRB2, AVP, AVPR2, CALCR, CALM1, CALM3, CRH, DRD5, EDNRA, FSHR, GCG, GHRH, GHRHR, GLP1R, GNAL, GNAS, INSL3, NTRK1, NTRK2, P2RY11, PTGER4, PTHLH, RAF1, UCN, VIP, VIPR2, WFS1, AKAP12, CALCRL, RAMP2, CAP1 |
262 | GO:0071385 | 0.00 | 7.85 | 6.35 | 14 | 17 | cellular response to glucocorticoid stimulus | ACVR1, ANXA1, ATP2B1, KLF9, FLT3, HMGCS2, IL17A, ISL1, REST, SGK1, SSTR2, STC1, UBE2L3, AKAP13 |
263 | GO:0007584 | 0.00 | 7.81 | 18.55 | 41 | 50 | response to nutrient | ABCA1, ADSL, AHCY, ALB, ALDH3A1, APAF1, APOA1, ASS1, BRCA1, BRCA2, CD3E, CHAT, CNR1, COX4I1, DAD1, DDIT3, ERCC1, ACSL1, ACSL3, ACSL4, GCGR, HMGCL, HMGCR, HMGCS2, IGF1, IGFBP2, LDHA, TNFRSF11B, OXCT1, PTEN, RPS6KB1, SLC16A1, SSTR2, STAR, SUOX, VCAM1, OGT, HAT1, AKR1C3, LIPG, SLC27A4 |
264 | GO:0010243 | 0.00 | 7.75 | 16.70 | 38 | 47 | response to organonitrogen compound | ADSS, AGTR2, AGXT, ALDH3A1, BIRC2, ATP4B, ATP7B, CCND1, TSPO, CASP1, CCNE1, CDKN1A, DGKQ, DHFR, DUSP1, FLT3, HLCS, HMGCS1, IRAK1, JUN, LDHA, P2RX1, P2RX3, P2RX5, P2RX7, PAX4, PER1, PTEN, PTGS1, PYGM, SELL, TP73, TRPC3, TYR, FOSL1, KYNU, SLC22A6, CARM1 |
265 | GO:0045669 | 0.00 | 7.74 | 10.47 | 23 | 28 | positive regulation of osteoblast differentiation | ACVR1, ACVR2A, ACVR2B, JAG1, ATP6AP1, BMP4, BMP6, BMPR1A, BMPR2, RUNX2, DLX5, GNAS, HGF, IGF1, ILK, JUND, LTF, SMAD1, PRKD1, PTGER4, SOX11, TP63, PDLIM7 |
266 | GO:0044344 | 0.00 | 7.69 | 4.07 | 9 | 11 | cellular response to fibroblast growth factor stimulus | CD44, CDC5L, COL1A1, CPS1, EGR3, SNCA, STAR, ITGB1BP1, CXCL13 |
267 | GO:0050810 | 0.00 | 7.57 | 4.11 | 9 | 11 | regulation of steroid biosynthetic process | BMP6, TSPO, FGFR4, NR5A1, IFNG, IL1B, STAR, AKR1C3, DDX20 |
268 | GO:0010939 | 0.00 | 7.56 | 4.11 | 9 | 11 | regulation of necrotic cell death | TSPO, IL17A, TRAF2, UBB, UCN, TRADD, TNFSF10, TNFRSF10B, TNFRSF10A |
269 | GO:0009651 | 0.00 | 7.55 | 4.11 | 9 | 11 | response to salt stress | ANXA7, AVP, BAX, BDKRB2, HIF1A, HSP90AB1, SLC12A1, TACR3, SLC12A6 |
270 | GO:0010881 | 0.00 | 7.55 | 4.11 | 9 | 11 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion | ATP1A2, CALM1, CALM3, CASQ2, GSTM2, HRC, PLN, RYR2, GSTO1 |
271 | GO:0060307 | 0.00 | 7.55 | 4.11 | 9 | 11 | regulation of ventricular cardiac muscle cell membrane repolarization | CAV3, GJA5, KCNE1, KCNH2, KCNQ1, SCN4B, SCN5A, KCNE2, AKAP9 |
272 | GO:0072148 | 0.00 | 7.55 | 4.11 | 9 | 11 | epithelial cell fate commitment | ACVR1, ATOH1, FGFR3, GATA4, HES1, RBPJ, RARA, NR2F2, NRP1 |
273 | GO:0097296 | 0.00 | 7.55 | 4.11 | 9 | 11 | activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | BAX, SMAD3, TRAF2, TRADD, RIPK1, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR |
274 | GO:0060333 | 0.00 | 7.43 | 10.08 | 22 | 27 | interferon-gamma-mediated signaling pathway | CAMK2A, CD44, FCGR1A, FCGR1B, HCK, HLA-DQA1, ICAM1, IRF1, IRF2, IRF5, CIITA, OAS2, OAS3, PRKCD, PTAFR, SP100, TRIM21, VCAM1, TRIM25, TRIM22, IFI30, TRIM38 |
275 | GO:0045446 | 0.00 | 7.31 | 5.97 | 13 | 16 | endothelial cell differentiation | ACVR1, ACVR2B, JAG1, BMPR2, S1PR1, NRG1, RBPJ, KDR, LAMA5, PTN, NR2F2, EDF1, NRP1 |
276 | GO:0032026 | 0.00 | 7.28 | 5.98 | 13 | 16 | response to magnesium ion | CCND1, BMP6, C3, ENTPD6, KCNA1, KCNC2, KCNJ1, LIPC, TNFRSF11B, RYR3, SLC34A1, SNCA, FGF23 |
277 | GO:0050927 | 0.00 | 7.28 | 5.98 | 13 | 16 | positive regulation of positive chemotaxis | AKT2, S1PR1, F2RL1, F3, F7, KDR, SMAD3, NTF3, NTRK3, VEGFB, VEGFC, SCG2, CREB3 |
278 | GO:0071392 | 0.00 | 7.28 | 5.98 | 13 | 16 | cellular response to estradiol stimulus | CRHBP, ESR1, H2AFZ, HNRNPD, IGF1, IL10, PAWR, SRD5A1, SSTR2, NRIP1, AIFM1, RAMP3, RUVBL2 |
279 | GO:2000772 | 0.00 | 7.28 | 5.98 | 13 | 16 | regulation of cellular senescence | ABL1, ARNTL, BMPR1A, CDK6, CDKN2A, HMGA1, ING2, TWIST1, HMGA2, TP63, EEF1E1, NUAK1, ZNF277 |
280 | GO:0009611 | 0.00 | 7.18 | 7.18 | 16 | 20 | response to wounding | ACHE, ADM, DST, CD81, CTGF, GFAP, GRIN2A, ITGB4, PAWR, RPS6KB1, SCN3A, SRSF5, SLC1A3, WNT1, NRP1, ABHD2 |
281 | GO:0006335 | 0.00 | 7.14 | 7.85 | 17 | 21 | DNA replication-dependent nucleosome assembly | CHAF1B, HIST1H4I, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HAT1, HIST1H3F |
282 | GO:0007190 | 0.00 | 7.14 | 7.85 | 17 | 21 | activation of adenylate cyclase activity | ADRB2, AVPR2, CALM1, CALM3, DRD5, EDNRA, FSHR, GHRHR, GLP1R, GNAL, GNAS, NTRK1, NTRK2, P2RY11, RAF1, VIPR2, CAP1 |
283 | GO:0046903 | 0.00 | 7.09 | 5.42 | 12 | 15 | secretion | AVPR2, CA2, COMT, EDNRA, UTS2R, NRG1, PRKCI, STC1, TPD52, SLC22A6, FBLN5, CORIN |
284 | GO:0031281 | 0.00 | 7.08 | 9.71 | 21 | 26 | positive regulation of cyclase activity | ADRB2, AVPR2, CALCR, CALM1, CALM3, DRD5, EDNRA, FSHR, GHRHR, GLP1R, GNAL, GNAS, NTRK1, NTRK2, P2RY11, MAPK8, RAF1, VIP, VIPR2, WFS1, CAP1 |
285 | GO:0071398 | 0.00 | 7.02 | 11.59 | 25 | 31 | cellular response to fatty acid | ADCY6, ASS1, CCNB1, CPS1, CREB1, GNAS, GNB1, FFAR3, HMGCS2, IL1B, P2RY4, P2RY6, PDK4, PRKAA1, PRKCE, PTAFR, PTGDR, PTGER2, PTGER4, SMARCD1, SREBF1, TNFSF4, AKR1C3, ADAMTS1, NR1H4 |
286 | GO:0003012 | 0.01 | 6.89 | 3.68 | 8 | 10 | muscle system process | GTF2I, IL1B, IL15, P2RY1, SLN, TBCE, CFLAR, KLF4 |
287 | GO:0044706 | 0.00 | 6.84 | 5.55 | 12 | 15 | multi-multicellular organism process | ACVR2A, ARNTL, EDNRA, B4GALT1, SMCP, P2RX1, PTAFR, SEMG1, TAC1, TNP2, DDO, EDDM3A |
288 | GO:0043200 | 0.00 | 6.77 | 9.32 | 20 | 25 | response to amino acid | AARS, ALAD, ALDOB, ARG1, BAD, CDO1, CHUK, CPS1, CREB1, CTGF, HMBS, ICAM1, IL17A, LIPC, PIK3C3, PTGER4, PTN, RPS6KB1, AIFM1, PEMT |
289 | GO:0007602 | 0.01 | 6.75 | 3.72 | 8 | 10 | phototransduction | GNAT2, GNGT2, PDC, RGR, TRPC3, UNC119, NR2E3, RRH |
290 | GO:0051349 | 0.00 | 6.74 | 9.34 | 20 | 25 | positive regulation of lyase activity | ADRB2, AVPR2, CALCR, CALM1, CALM3, DRD5, EDNRA, FSHR, GHRHR, GLP1R, GNAL, GNAS, NTRK1, NTRK2, P2RY11, RAF1, VIP, VIPR2, WFS1, CAP1 |
291 | GO:0014075 | 0.01 | 6.74 | 3.73 | 8 | 10 | response to amine | ARG1, ASS1, CPS1, HMBS, HNMT, KCNC1, KCNC2, UROS |
292 | GO:0019320 | 0.01 | 6.73 | 3.73 | 8 | 10 | hexose catabolic process | FUT6, FUT8, GALE, GALK1, GLB1, KHK, PGM1, FUT9 |
293 | GO:0006383 | 0.00 | 6.72 | 5.61 | 12 | 15 | transcription from RNA polymerase III promoter | BRCA1, ERBB2, GTF3A, BRF1, SNAPC1, SNAPC2, SNAPC3, TROVE2, TBP, ZNF76, ZNF143, IVNS1ABP |
294 | GO:0098900 | 0.00 | 6.72 | 5.61 | 12 | 15 | regulation of action potential | CXADR, DSC2, DSP, GJA5, IFNG, KCNJ2, NTSR1, PAWR, RYR2, SCN5A, SLC9A1, TAC1 |
295 | GO:0001975 | 0.00 | 6.72 | 7.48 | 16 | 20 | response to amphetamine | ADRA1B, CALM1, CALM3, CNR2, DBH, DDIT3, DRD3, DRD5, GNAL, GRIN2A, HPRT1, ICAM1, OXTR, PDE1B, RANBP2, SOD1 |
296 | GO:1901021 | 0.01 | 6.72 | 3.74 | 8 | 10 | positive regulation of calcium ion transmembrane transporter activity | BMP4, RYR2, S100A1, SLC9A1, SUMO1, RGN, KCNE2, KCNE3 |
297 | GO:0010039 | 0.00 | 6.72 | 5.61 | 12 | 15 | response to iron ion | ABAT, ACO1, ALAD, CCND1, BCL2, BMP6, C1QA, CCNB1, CPOX, SLC11A2, PAWR, SNCA |
298 | GO:0010644 | 0.00 | 6.72 | 5.61 | 12 | 15 | cell communication by electrical coupling | ATP1A1, ATP1A2, ATP1A3, CALM1, CALM3, CASQ2, GJA5, HRC, KCNA1, PDE4D, RYR2, TRDN |
299 | GO:0042119 | 0.00 | 6.72 | 5.61 | 12 | 15 | neutrophil activation | ANXA3, BCR, ACKR2, F2RL1, FCER1G, PRKCD, PTAFR, STXBP2, STXBP3, TYROBP, STX11, PRG3 |
300 | GO:0051412 | 0.00 | 6.72 | 5.61 | 12 | 15 | response to corticosterone | ATP2B1, BAX, CCND1, CALM1, CALM3, CCNE1, CDKN1A, CRH, NTRK3, PTGS1, STAR, FOSL1 |
301 | GO:0071242 | 0.00 | 6.72 | 5.61 | 12 | 15 | cellular response to ammonium ion | ABL1, ASS1, CRH, CRHBP, DIAPH1, DNM2, HNRNPD, HRH1, KCNC2, PARK2, PTAFR, SLC34A1 |
302 | GO:0001913 | 0.01 | 6.71 | 3.74 | 8 | 10 | T cell mediated cytotoxicity | CTSH, EMP2, IL12B, P2RX7, PVR, RAB27A, XCL1, STX11 |
303 | GO:0002507 | 0.01 | 6.71 | 3.74 | 8 | 10 | tolerance induction | C3, CBLB, CD3E, CD86, CLC, IL2RA, IDO1, TNFAIP3 |
304 | GO:0006362 | 0.01 | 6.71 | 3.74 | 8 | 10 | transcription elongation from RNA polymerase I promoter | CCNH, ERCC3, ERCC6, TBP, UBTF, TAF1C, TAF1B, TAF1A |
305 | GO:0006363 | 0.01 | 6.71 | 3.74 | 8 | 10 | termination of RNA polymerase I transcription | CCNH, ERCC3, TBP, TTF1, UBTF, TAF1C, TAF1B, TAF1A |
306 | GO:0009886 | 0.01 | 6.71 | 3.74 | 8 | 10 | post-embryonic morphogenesis | ATRX, BAX, FBN1, EFEMP1, GNAS, HMGN1, KDR, BCL2L11 |
307 | GO:0017187 | 0.01 | 6.71 | 3.74 | 8 | 10 | peptidyl-glutamic acid carboxylation | BGLAP, F2, F7, F10, GAS6, GGCX, PROC, PROZ |
308 | GO:0033057 | 0.01 | 6.71 | 3.74 | 8 | 10 | multicellular organism reproductive behavior | AVP, DBH, DRD5, GNAQ, GRN, HEXB, OXTR, PTEN |
309 | GO:0035886 | 0.01 | 6.71 | 3.74 | 8 | 10 | vascular smooth muscle cell differentiation | ADM, CTH, GATA6, HES1, SGCB, SMARCA2, SRF, RAMP2 |
310 | GO:0035988 | 0.01 | 6.71 | 3.74 | 8 | 10 | chondrocyte proliferation | BMPR2, CTGF, FGFR3, GRN, IHH, LTF, STC1, HMGA2 |
311 | GO:0036092 | 0.01 | 6.71 | 3.74 | 8 | 10 | phosphatidylinositol-3-phosphate biosynthetic process | ATM, INPP4A, PIK3C2B, PIK3C3, PIK3CB, PIK3R3, INPP4B, FIG4 |
312 | GO:0043568 | 0.01 | 6.71 | 3.74 | 8 | 10 | positive regulation of insulin-like growth factor receptor signaling pathway | CDH3, GHRH, GHRHR, GHSR, IGF1, IGFBP3, IGFBP5, WNT1 |
313 | GO:0045663 | 0.01 | 6.71 | 3.74 | 8 | 10 | positive regulation of myoblast differentiation | BTG1, FLT3LG, IGFBP3, ILK, MAP3K5, NR2C2, CSRP3, TNFSF14 |
314 | GO:0046885 | 0.01 | 6.71 | 3.74 | 8 | 10 | regulation of hormone biosynthetic process | ARNT, ATP1A1, BMP6, CACNA1A, FFAR3, HIF1A, REST, AKR1C3 |
315 | GO:0048486 | 0.01 | 6.71 | 3.74 | 8 | 10 | parasympathetic nervous system development | PHOX2A, EGR2, HES1, SEMA3F, SIX1, NRP1, PHOX2B, SEMA3A |
316 | GO:0048670 | 0.01 | 6.71 | 3.74 | 8 | 10 | regulation of collateral sprouting | DCC, EFNA5, EPHA7, IFRD1, OMG, RND2, IST1, SEMA4D |
317 | GO:0060421 | 0.01 | 6.71 | 3.74 | 8 | 10 | positive regulation of heart growth | ACACB, CCNB1, GATA4, GATA6, NRG1, RBPJ, WNT2, AKAP6 |
318 | GO:0060670 | 0.01 | 6.71 | 3.74 | 8 | 10 | branching involved in labyrinthine layer morphogenesis | ADM, GRB2, IL10, LLGL2, SPINT1, ST14, FZD5, SOCS3 |
319 | GO:0071425 | 0.01 | 6.71 | 3.74 | 8 | 10 | hematopoietic stem cell proliferation | ACE, ETV6, KITLG, EIF2AK2, WNT1, WNT2B, PRG4, ARIH2 |
320 | GO:0071872 | 0.01 | 6.71 | 3.74 | 8 | 10 | cellular response to epinephrine stimulus | KCNQ1, PDE4B, PDE4D, RYR2, SLC9A1, SNCA, SRD5A1, STAR |
321 | GO:0090670 | 0.01 | 6.71 | 3.74 | 8 | 10 | RNA localization to Cajal body | CCT6A, DKC1, CCT3, RUVBL1, CCT7, CCT4, CCT2, RUVBL2 |
322 | GO:0090672 | 0.01 | 6.71 | 3.74 | 8 | 10 | telomerase RNA localization | CCT6A, DKC1, CCT3, RUVBL1, CCT7, CCT4, CCT2, RUVBL2 |
323 | GO:1904874 | 0.01 | 6.71 | 3.74 | 8 | 10 | positive regulation of telomerase RNA localization to Cajal body | CCT6A, DKC1, CCT3, RUVBL1, CCT7, CCT4, CCT2, RUVBL2 |
324 | GO:0043434 | 0.00 | 6.68 | 8.73 | 19 | 24 | response to peptide hormone | ANXA1, AREG, STS, BSG, BTG1, COL1A1, CTGF, EIF2B1, GNAI1, JUND, LIPC, LTA4H, OXTR, SPARC, TRPV1, EIF2B3, EIF2B2, EIF2B5, RNF40 |
325 | GO:0006937 | 0.00 | 6.50 | 19.75 | 42 | 53 | regulation of muscle contraction | ANXA6, ATP1A1, ATP2A1, CALM1, CALM3, CASQ1, CASQ2, CAV3, CTGF, DSC2, DSP, GATA4, GJA5, GSTM2, HRC, KCNA1, KCNJ2, KCNQ1, SMAD7, PPP1R12B, P2RX4, PDE4B, PDE4D, PLN, RYR2, SCN5A, SCN10A, SLC8A3, SLC9A1, SSTR2, STC1, TNNC2, TNNC1, TNNI2, TNNT1, TNNT2, SUMO1, UCN, PDE5A, GSTO1, HDAC4, HCN4 |
326 | GO:0035150 | 0.00 | 6.48 | 28.80 | 61 | 77 | regulation of tube size | ADCY6, ADM, ADRA1B, ADRA2A, ADRB2, AGTR1, AGTR2, ALOX12, ATP1A2, AVP, AVPR1B, AVPR2, BBS2, BDKRB2, BMPR2, CD38, CHRM1, CHRM3, CPS1, CRP, DBH, ACE, DRD5, EDN3, EDNRA, F2R, F2RL1, FGA, FGG, GJA5, UTS2R, GPX1, HIF1A, HMGCR, HRH1, HRH2, ICAM1, INS, ITGA1, KCNJ8, KNG1, OXTR, P2RX1, P2RX4, P2RY1, P2RY2, PRKCQ, PTAFR, PTGS1, PTPRM, RGS2, CX3CL1, SHC1, SOD1, SOD2, UCN, VIP, KAT2B, ITGB1BP1, ATG5, KCNMB2 |
327 | GO:0034332 | 0.00 | 6.42 | 8.95 | 19 | 24 | adherens junction organization | ACTB, ACTG1, ANG, CDC42, CDH1, CDH3, CDH6, CDH7, CDH8, CDH9, CDH10, CDH12, CDH15, CDH17, CTNNA1, DSP, PVR, NUMB, NUMBL |
328 | GO:0071867 | 0.00 | 6.39 | 8.98 | 19 | 24 | response to monoamine | ABL1, ADCY6, ADRB2, APLP1, APP, DNM2, DRD5, GNAS, GNB1, KCNQ1, PARK2, PDE4B, PDE4D, PENK, RYR2, SLC9A1, SNCA, SRD5A1, STAR |
329 | GO:0006940 | 0.00 | 6.31 | 7.10 | 15 | 19 | regulation of smooth muscle contraction | ADRA2A, ADRB2, ATP1A2, CHRM1, CHRNB4, CNN1, DAPK3, FLT1, GHSR, P2RX1, PTGER4, RGS2, SOD1, TNNI3, CALCRL |
330 | GO:0006695 | 0.00 | 6.31 | 7.10 | 15 | 19 | cholesterol biosynthetic process | ACLY, APOA1, CFTR, CYP51A1, DHCR24, CYB5R3, FDFT1, FDPS, HMGCR, HMGCS1, HMGCS2, INSIG1, CNBP, ACAA2, EBP |
331 | GO:0045471 | 0.00 | 6.30 | 29.92 | 63 | 80 | response to ethanol | ABAT, ALAD, BIRC2, ATP5G3, AVP, BAD, CCND1, BGLAP, CAT, CCNE1, CDK2, CDO1, CHAT, CHRNB2, CNR1, CRH, CRHBP, DBH, DNMT1, EEF2, EIF4EBP1, EPS8, PTK2B, FYN, GLRA1, GLRA2, GOT2, GRIN2A, HMGCR, HMGCS2, HTR3A, ICAM1, IGF2, IL1B, IL13, ITPR2, KCNC2, MGMT, NTRK1, NTRK3, OGG1, OXCT1, PENK, PRKAA1, PRKCE, PTEN, RARA, RPS6KB1, RXRA, S100A8, ST6GAL1, SLC2A4, SOD1, SPARC, STAR, STAT3, STAT5B, TYMS, VCAM1, GGH, SETDB1, PSMD14, PEMT |
332 | GO:0005980 | 0.00 | 6.30 | 7.11 | 15 | 19 | glycogen catabolic process | ADRA1B, CALM1, CALM3, CPS1, G6PC, GAA, INS, PGM1, PHKA1, PHKA2, PHKB, PHKG1, PYGB, PYGL, PYGM |
333 | GO:2000352 | 0.00 | 6.30 | 7.11 | 15 | 19 | negative regulation of endothelial cell apoptotic process | ABL1, ABL2, ANGPT1, KRIT1, FGA, FGG, GAS6, ICAM1, IL13, KDR, SERPINE1, TNFAIP3, SCG2, SEMA5A, RAMP2 |
334 | GO:0002576 | 0.00 | 6.25 | 17.58 | 37 | 47 | platelet degranulation | A2M, ACTN1, ALB, APOA1, APP, SERPING1, CALM1, CALM3, CALU, CD9, CD36, CD63, CLU, FCER1G, FGA, FGG, GAS6, HGF, HRG, IGF1, IGF2, KNG1, LAMP2, P2RX1, SERPINE1, PF4, PFN1, PSAP, SELP, SOD1, SPARC, STXBP1, TUBA4A, VEGFB, VEGFC, ABCC4, CAP1 |
335 | GO:0043279 | 0.00 | 6.23 | 5.20 | 11 | 14 | response to alkaloid | BCHE, EDNRA, FGA, HIF1A, IL1B, PPP2R2A, PPP5C, PRKCE, TAC1, UQCRC1, PEA15 |
336 | GO:0008585 | 0.00 | 6.20 | 5.21 | 11 | 14 | female gonad development | AMHR2, BRCA2, COL9A3, FANCA, IDH1, PGR, SLIT3, UBB, NRIP1, SLIT2, ADAMTS1 |
337 | GO:0015698 | 0.00 | 6.18 | 5.22 | 11 | 14 | inorganic anion transport | AQP6, ASNA1, CRY2, SFRP4, SLC5A5, SLC11A1, SLC13A1, SLC34A1, SLC20A1, FGF23, SLC34A2 |
338 | GO:0033198 | 0.00 | 6.16 | 5.23 | 11 | 14 | response to ATP | CASP1, DGKQ, IL1B, KCNJ11, P2RX1, P2RX3, P2RX5, P2RX7, PTEN, SELL, TRPC3 |
339 | GO:0006883 | 0.00 | 6.15 | 5.24 | 11 | 14 | cellular sodium ion homeostasis | AGTR2, ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP1A4, ATP1B3, ATP4A, SGK1, SLC9A1, SGK2 |
340 | GO:0010575 | 0.00 | 6.15 | 5.24 | 11 | 14 | positive regulation of vascular endothelial growth factor production | ARNT, ATF4, BRCA1, C3, FLT4, GATA4, HIF1A, IL1A, IL1B, ISL1, EIF2AK3 |
341 | GO:0030325 | 0.00 | 6.15 | 5.24 | 11 | 14 | adrenal gland development | NR0B1, APOA1, ASCL1, TSPO, CRH, NR5A1, PBX1, SALL1, WNT11, FSTL3, CITED2 |
342 | GO:0097435 | 0.00 | 6.15 | 5.24 | 11 | 14 | fibril organization | APP, CD36, COL3A1, GPX1, HSPA8, HSP90AB1, ILK, LTBP2, SNCA, RIPK1, ADAMTS3 |
343 | GO:0003018 | 0.00 | 6.09 | 32.54 | 68 | 87 | vascular process in circulatory system | ADCY6, ADM, ADRA1B, ADRA2A, ADRB2, AGTR1, AGTR2, ALOX12, ANGPT1, ATP1A2, AVP, AVPR1B, AVPR2, BBS2, BCR, BDKRB2, BMPR2, CD38, CHRM1, CHRM3, CPS1, CRP, DBH, ACE, DRD5, EDN3, EDNRA, F2R, F2RL1, FGA, FGG, GJA5, UTS2R, GPX1, ARHGAP35, HIF1A, HMGCR, HRH1, HRH2, ICAM1, INS, ITGA1, KCNJ8, KNG1, OXTR, P2RX1, P2RX4, P2RY1, P2RY2, PDE3A, PRKCQ, PTAFR, PTGS1, PTPRJ, PTPRM, RGS2, CX3CL1, SHC1, SOD1, SOD2, UCN, VIP, KAT2B, ITGB1BP1, SLIT2, ATG5, KCNMB2, RAMP2 |
344 | GO:1900544 | 0.00 | 6.07 | 20.55 | 43 | 55 | positive regulation of purine nucleotide metabolic process | ABCA1, ADM, ADRB2, ARNT, AVP, AVPR2, CALCR, CALM1, CALM3, CRH, DRD5, EDNRA, FSHR, GCG, GHRH, GHRHR, GLP1R, GNAL, GNAS, GPD1, HIF1A, IGF1, INS, INSL3, NTRK1, NTRK2, P2RX7, P2RY11, PF4, PRKAA1, PTGER4, PTHLH, RAF1, STAT3, UCN, VIP, VIPR2, WFS1, AKAP12, CALCRL, RAMP2, RAPGEF3, CAP1 |
345 | GO:0007611 | 0.00 | 5.97 | 6.66 | 14 | 18 | learning or memory | STS, CRHBP, DBI, EGR2, AFF2, GLP1R, GM2A, MAN2B1, SLC11A2, NTRK1, PRKAR1B, VIP, KCNAB1, FZD9 |
346 | GO:0051270 | 0.00 | 5.96 | 8.01 | 17 | 22 | regulation of cellular component movement | ATP1A1, ATP1A2, DSC2, DSP, GATA4, B4GALT1, GJA5, IGBP1, KCNJ2, PDE4B, PDE4D, PLN, RYR2, SCN5A, TNNC1, TNNT2, SUMO1 |
347 | GO:0007187 | 0.02 | 5.94 | 3.34 | 7 | 9 | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | AGTR2, ANXA1, CNR2, GPR1, XCR1, HRH2, VIPR1 |
348 | GO:0050921 | 0.02 | 5.92 | 3.35 | 7 | 9 | positive regulation of chemotaxis | BMPR2, LPAR1, HSPB1, PRKD1, NRP1, SEMA5A, SLIT2 |
349 | GO:0032200 | 0.02 | 5.90 | 3.35 | 7 | 9 | telomere organization | HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H3F |
350 | GO:2001057 | 0.00 | 5.90 | 13.46 | 28 | 36 | reactive nitrogen species metabolic process | AGTR2, AKT2, ARG2, ASS1, TSPO, CALM1, CALM3, CLU, CPS1, DHFR, DNM2, ESR1, PTK2B, HSP90AA1, HSP90AB1, ICAM1, IFNG, IGF1, IL1B, IL10, INS, P2RX4, PTGIS, SUOX, TRPV1, RGN, KLF4, KLF2 |
351 | GO:0045776 | 0.00 | 5.89 | 6.72 | 14 | 18 | negative regulation of blood pressure | ABAT, BDKRB2, CNR1, CRH, DRD3, DRD5, GJA5, UTS2R, FFAR3, GUCA2B, PTAFR, RNPEP, UCN, VEGFC |
352 | GO:0010524 | 0.02 | 5.89 | 3.36 | 7 | 9 | positive regulation of calcium ion transport into cytosol | BMP4, CD4, P2RX3, P2RX4, P2RX5, P2RX7, TRPC3 |
353 | GO:0010463 | 0.02 | 5.88 | 3.36 | 7 | 9 | mesenchymal cell proliferation | BMP4, FGF4, FGF7, GPC3, PTN, ZEB1, WNT11 |
354 | GO:0060306 | 0.00 | 5.88 | 6.73 | 14 | 18 | regulation of membrane repolarization | CASQ2, CAV3, GJA5, KCNE1, KCNH2, KCNJ2, KCNQ1, SCN4B, SCN5A, AKAP7, AKAP6, KCNE2, KCNE3, AKAP9 |
355 | GO:1903018 | 0.00 | 5.88 | 6.73 | 14 | 18 | regulation of glycoprotein metabolic process | APCS, BCL2, HBEGF, GOLGA2, IGF1, IL15, PAWR, RAB1A, CCL21, KAT2B, TMEM59, ACOT8, ABCA7, ARFGEF1 |
356 | GO:0001977 | 0.02 | 5.87 | 3.37 | 7 | 9 | renal system process involved in regulation of blood volume | CYBA, EMP2, F2R, F2RL1, GAS6, GJA5, UTS2R |
357 | GO:0002070 | 0.02 | 5.87 | 3.37 | 7 | 9 | epithelial cell maturation | CDKN1A, HIF1A, PGR, RFX3, SIX3, TYMS, FEM1B |
358 | GO:0007191 | 0.02 | 5.87 | 3.37 | 7 | 9 | adenylate cyclase-activating dopamine receptor signaling pathway | ADCY5, DRD3, DRD5, GNAL, GNAS, GNB1, SLC9A3R1 |
359 | GO:0007617 | 0.02 | 5.87 | 3.37 | 7 | 9 | mating behavior | APLP2, APP, AVP, DRD5, GRN, HEXB, PTEN |
360 | GO:0009650 | 0.02 | 5.87 | 3.37 | 7 | 9 | UV protection | CAT, ERCC1, ERCC3, ERCC4, ERCC5, FEN1, GPX1 |
361 | GO:0010042 | 0.02 | 5.87 | 3.37 | 7 | 9 | response to manganese ion | ARG1, ATF4, TSPO, EIF2S1, PARK2, ADAM9, EIF2AK3 |
362 | GO:0021781 | 0.02 | 5.87 | 3.37 | 7 | 9 | glial cell fate commitment | ASCL1, NRG1, NTF3, SOX2, SOX9, TAL1, OLIG2 |
363 | GO:0023019 | 0.02 | 5.87 | 3.37 | 7 | 9 | signal transduction involved in regulation of gene expression | FGF5, GATA4, FOXA2, EPCAM, SMAD3, P2RY1, CER1 |
364 | GO:0030207 | 0.02 | 5.87 | 3.37 | 7 | 9 | chondroitin sulfate catabolic process | VCAN, CSPG4, DCN, HEXA, HEXB, IDS, IDUA |
365 | GO:0030728 | 0.02 | 5.87 | 3.37 | 7 | 9 | ovulation | EREG, HPGD, IL1B, IL1R1, PGR, NRIP1, ADAMTS1 |
366 | GO:0030825 | 0.02 | 5.87 | 3.37 | 7 | 9 | positive regulation of cGMP metabolic process | FZD2, GUCA1A, GUCA1B, GUCA2A, GUCA2B, RCVRN, GUCA1C |
367 | GO:0032075 | 0.02 | 5.87 | 3.37 | 7 | 9 | positive regulation of nuclease activity | BAX, ERN1, PCNA, PRKCD, PTPN1, RPS3, VAPB |
368 | GO:0032516 | 0.02 | 5.87 | 3.37 | 7 | 9 | positive regulation of phosphoprotein phosphatase activity | AGTR2, CALM1, CALM3, ITGA1, PPP1R12A, PAWR, AKAP6 |
369 | GO:0033604 | 0.02 | 5.87 | 3.37 | 7 | 9 | negative regulation of catecholamine secretion | ABAT, ADRA2A, AGTR2, CNR1, CRH, P2RY1, PTGS1 |
370 | GO:0035930 | 0.02 | 5.87 | 3.37 | 7 | 9 | corticosteroid hormone secretion | AGTR1, AGTR2, BMP6, CRH, CRY1, GALR1, TAC1 |
371 | GO:0035994 | 0.02 | 5.87 | 3.37 | 7 | 9 | response to muscle stretch | CAV3, CHUK, JUN, RAF1, RYR2, SLC9A1, CSRP3 |
372 | GO:0042511 | 0.02 | 5.87 | 3.37 | 7 | 9 | positive regulation of tyrosine phosphorylation of Stat1 protein | FGFR3, HPX, IFNG, KIT, TNFRSF1A, TNFRSF18, TNFSF18 |
373 | GO:0042994 | 0.02 | 5.87 | 3.37 | 7 | 9 | cytoplasmic sequestering of transcription factor | IL10, TONSL, TRIP6, TNFSF14, KEAP1, TACC3, CREB3 |
374 | GO:0043092 | 0.02 | 5.87 | 3.37 | 7 | 9 | L-amino acid import | ARG1, ATP1A2, KCNJ10, NTSR1, SLC1A3, SLC11A1, SLC6A5 |
375 | GO:0045540 | 0.02 | 5.87 | 3.37 | 7 | 9 | regulation of cholesterol biosynthetic process | DHCR7, PRKAA1, SOD1, SREBF1, ABCG1, ERLIN1, ERLIN2 |
376 | GO:0045603 | 0.02 | 5.87 | 3.37 | 7 | 9 | positive regulation of endothelial cell differentiation | ACVRL1, ALOX12, BMP4, BMP6, BTG1, PROC, S1PR2 |
377 | GO:0045989 | 0.02 | 5.87 | 3.37 | 7 | 9 | positive regulation of striated muscle contraction | ATP1A1, ATP2A1, CTGF, KCNQ1, RGS2, UCN, GSTO1 |
378 | GO:0051131 | 0.02 | 5.87 | 3.37 | 7 | 9 | chaperone-mediated protein complex assembly | APCS, CLU, HSPA4, HSP90AA1, HDAC6, CCT2, CCT6B |
379 | GO:0051580 | 0.02 | 5.87 | 3.37 | 7 | 9 | regulation of neurotransmitter uptake | ATP1A2, DRD3, GFAP, PARK2, RAB3B, SLC18A1, SNCA |
380 | GO:0055098 | 0.02 | 5.87 | 3.37 | 7 | 9 | response to low-density lipoprotein particle | ABCA1, CD9, CD36, CD81, F3, FCER1G, ITGB1 |
381 | GO:0060218 | 0.02 | 5.87 | 3.37 | 7 | 9 | hematopoietic stem cell differentiation | CDK6, CHD2, ACE, EIF2AK2, SRF, TAL1, XRCC5 |
382 | GO:0060788 | 0.02 | 5.87 | 3.37 | 7 | 9 | ectodermal placode formation | CDC42, EDA, GNAS, SIX1, SOX2, NRP1, NRG3 |
383 | GO:0071696 | 0.02 | 5.87 | 3.37 | 7 | 9 | ectodermal placode development | CDC42, EDA, GNAS, SIX1, SOX2, NRP1, NRG3 |
384 | GO:1900116 | 0.02 | 5.87 | 3.37 | 7 | 9 | extracellular negative regulation of signal transduction | AGTR2, FBN1, LRPAP1, LTBP1, CD46, CER1, IL18BP |
385 | GO:1900409 | 0.02 | 5.87 | 3.37 | 7 | 9 | positive regulation of cellular response to oxidative stress | PARK2, SFPQ, SNCA, SOD1, TRPM2, RGN, HDAC6 |
386 | GO:2000136 | 0.02 | 5.87 | 3.37 | 7 | 9 | regulation of cell proliferation involved in heart morphogenesis | BMP4, EYA1, HES1, RBPJ, ISL1, SIX1, SOX9 |
387 | GO:2000831 | 0.02 | 5.87 | 3.37 | 7 | 9 | regulation of steroid hormone secretion | BMP6, CRH, CRY1, GALR1, GDF9, TAC1, TMF1 |
388 | GO:0007568 | 0.00 | 5.87 | 36.08 | 75 | 97 | aging | ABAT, ADM, ADRB2, ALDH3A1, ALOX12, APAF1, APOH, ARG1, ASS1, ATP2B1, ATP5G3, BAX, TSPO, SERPING1, CANX, CASP9, CAT, CD86, CLU, CNP, CNR1, COL3A1, CREB1, CTGF, CTNNA1, DCN, DDIT3, DNMT1, EDNRA, EEF2, EIF2S1, ENO3, F3, HMGCR, IGF1, IGFBP2, IL1B, IL10, IL15, IRAK1, JUN, JUND, KRT83, NTRK1, NTRK2, OGG1, P2RY1, P2RY2, PDE4D, SERPINF1, PENK, PRKCQ, PTGS1, RPN2, RPS6KB1, RXRA, CX3CL1, SHC1, SNCA, SOD2, SREBF1, STAT3, TACR3, TNFRSF1B, TYMS, VCAM1, MADCAM1, EIF2B5, SOCS3, RGN, AURKB, LITAF, KCNE2, CARM1, GJB6 |
389 | GO:0048588 | 0.00 | 5.75 | 8.19 | 17 | 22 | developmental cell growth | AGTR2, APP, CAV3, DCC, EFNA5, EPHA7, GATA4, GDF9, PRMT2, OMG, SOX9, RND2, SORBS2, CTDP1, AKAP6, IST1, ARIH2 |
390 | GO:0000272 | 0.00 | 5.71 | 8.23 | 17 | 22 | polysaccharide catabolic process | ADRA1B, CALM1, CALM3, CHIT1, CPS1, G6PC, GAA, INS, PGM1, PHKA1, PHKA2, PHKB, PHKG1, PYGB, PYGL, PYGM, MGAM |
391 | GO:0002548 | 0.00 | 5.71 | 8.23 | 17 | 22 | monocyte chemotaxis | ANXA1, FLT1, SERPINE1, RPS19, S100A7, S100A12, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, XCL2, TNFSF18, SLIT2, CREB3 |
392 | GO:0021983 | 0.00 | 5.71 | 8.23 | 17 | 22 | pituitary gland development | NR0B1, BMP4, BMPR1A, CDH1, CREB1, ETS1, GHRH, GHRHR, HES1, RBPJ, ISL1, SALL1, SIX3, SOX2, SOX3, SRD5A1, ALDH1A2 |
393 | GO:0038083 | 0.00 | 5.71 | 8.23 | 17 | 22 | peptidyl-tyrosine autophosphorylation | ABL1, ABL2, BLK, BTK, ACE, PTK2B, FGR, FRK, FYN, HCK, IGF1R, KDR, PTK2, SRMS, TNK1, AATK, TNK2 |
394 | GO:0048512 | 0.00 | 5.71 | 8.23 | 17 | 22 | circadian behavior | AHCY, ALB, CHRNB2, CRH, DRD3, GHRH, GHRHR, UTS2R, KCNA2, KCND2, PTEN, PTGER4, SIX3, SRD5A1, STAR, PER3, USP2 |
395 | GO:0071260 | 0.00 | 5.68 | 17.95 | 37 | 48 | cellular response to mechanical stimulus | ATP1A1, ATP1A2, BAD, BMP4, BMP6, BNIP3, CASP1, CASP5, TNFRSF8, CHEK1, CNN2, COL1A1, CYBA, GADD45A, EDNRA, F2, HIF1A, IGF2, IL1B, IL13, IL13RA2, IRF1, ITGB1, KCNJ2, MAPK8, PTGER4, RAC1, SLC9A1, SOX9, TNFRSF1A, CRADD, TNFSF14, TNFRSF10B, TNFRSF10A, BAG3, HDAC4, CASP8AP2 |
396 | GO:0032355 | 0.00 | 5.64 | 25.75 | 53 | 69 | response to estradiol | ANXA1, AREG, ASS1, BAD, CCND1, BID, BMP4, BRCA1, BRCA2, C3, CASP9, CAT, CCNE1, CD4, CD38, CDK2, COL1A1, CTGF, DNMT1, DNMT3B, DUSP1, EEF2, ETS1, F3, FGA, GRN, HIF1A, HMBS, IGF2, IGFBP2, IHH, IL1B, KCNJ11, OGG1, OXTR, PAM, PENK, PTEN, PTN, RARA, SLC34A1, STAT3, STAT5B, AURKA, TACR3, NR2F2, UCN, PRDM2, ALDH1A2, MBD4, SOCS3, RAMP2, TXNIP |
397 | GO:0034103 | 0.00 | 5.61 | 4.85 | 10 | 13 | regulation of tissue remodeling | BGLAP, CD38, CSF1R, S1PR1, IAPP, TNFRSF11B, P2RX7, PDK4, TNFAIP3, INPP4B |
398 | GO:0000302 | 0.00 | 5.61 | 11.13 | 23 | 30 | response to reactive oxygen species | ALDH3A2, BMP4, CDK2, DNM2, DPEP1, ERCC6, FANCC, GPX2, GPX3, GPX7, GUCY1B3, HNRNPD, IL1B, IL1R1, KCNC2, PRDX1, PTPRN, S100A7, SOD2, TRAF2, SCGB1A1, AKR1C3, PRDX6 |
399 | GO:0051281 | 0.00 | 5.60 | 4.86 | 10 | 13 | positive regulation of release of sequestered calcium ion into cytosol | ABL1, BAX, EDNRA, F2, F2R, IL13, NTSR1, XCL1, SNCA, TRPC1 |
400 | GO:0002068 | 0.00 | 5.59 | 4.86 | 10 | 13 | glandular epithelial cell development | ARNTL, BAD, BMP4, BMP6, CDK6, RARA, RARB, RFX3, RHEB, CLOCK |
401 | GO:0007597 | 0.00 | 5.59 | 4.86 | 10 | 13 | blood coagulation, intrinsic pathway | A2M, APOH, SERPING1, F2, F10, GP1BA, GP9, KLKB1, KNG1, PRCP |
402 | GO:0009954 | 0.00 | 5.59 | 4.86 | 10 | 13 | proximal/distal pattern formation | EN1, HOXC10, HOXC11, HOXD9, HOXD10, HOXD11, PBX1, SIX3, TP63, ALDH1A2 |
403 | GO:0019098 | 0.00 | 5.59 | 4.86 | 10 | 13 | reproductive behavior | APLP2, APP, AVP, DBH, DRD5, GNAQ, GRN, HEXB, OXTR, PTEN |
404 | GO:0032228 | 0.00 | 5.59 | 4.86 | 10 | 13 | regulation of synaptic transmission, GABAergic | CA2, CNR1, CNR2, KRAS, OXTR, PRKCE, PTEN, STXBP1, TAC1, SYN3 |
405 | GO:0032735 | 0.00 | 5.59 | 4.86 | 10 | 13 | positive regulation of interleukin-12 production | CD36, IFNG, IL12B, IDO1, IRF1, IRF5, ISL1, TNFSF4, TNFSF9, RIPK2 |
406 | GO:0042749 | 0.00 | 5.59 | 4.86 | 10 | 13 | regulation of circadian sleep/wake cycle | ALB, CHRNB2, CRH, DRD3, GHRH, GHRHR, UTS2R, KCNA2, PTGER4, PER3 |
407 | GO:0048569 | 0.00 | 5.59 | 4.86 | 10 | 13 | post-embryonic organ development | BAX, ERCC1, FBN1, EFEMP1, HMGN1, KDR, LDHA, FZD5, KLF4, BCL2L11 |
408 | GO:0060397 | 0.00 | 5.59 | 4.86 | 10 | 13 | JAK-STAT cascade involved in growth hormone signaling pathway | CISH, CSH1, GH2, PTPN1, PTPN6, STAT1, STAT3, STAT5B, ADAM17, SOCS3 |
409 | GO:0090077 | 0.00 | 5.59 | 4.86 | 10 | 13 | foam cell differentiation | ABCA1, AGTR1, ALOX15B, CD36, CRP, ITGAV, PF4, NR1H2, SOAT2, ABCG1 |
410 | GO:0007565 | 0.00 | 5.47 | 21.99 | 45 | 59 | female pregnancy | ADM, ADRA2A, ADRB2, AMBP, STS, BCL2, BYSL, CD38, COL16A1, COMT, CRH, CRHBP, EPYC, ETS1, ACSL4, FSHB, GNAS, HPGD, IGF1, IGF2, IGFBP2, IGFBP5, IDO1, INSL4, OVGP1, OXTR, PAPPA, PSG2, PSG3, PSG5, PSG6, PSG9, PSG11, PTGER4, PTHLH, PZP, RARA, RLN1, SP1, STAT5B, SULT1E1, UCN, FOSL1, RAMP2, CORIN |
411 | GO:0070059 | 0.00 | 5.47 | 6.35 | 13 | 17 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | APAF1, ATF4, ATP2A1, BAX, BCL2, CASP4, ERN1, UBE2K, ITPR1, MAP3K5, TRAF2, TNFRSF10B, AIFM1 |
412 | GO:0015872 | 0.00 | 5.46 | 6.36 | 13 | 17 | dopamine transport | ABAT, CHRNB2, CNR1, DRD3, KCNA2, PARK2, PCP4, RAB3B, SLC18A1, SLC22A1, SLC22A3, SLC22A2, SNCA |
413 | GO:0021884 | 0.00 | 5.46 | 6.36 | 13 | 17 | forebrain neuron development | DCX, GNAQ, OGDH, RAC1, RAC3, SOX1, CNTN2, UBB, NRP1, SLIT2, RAPGEF2, SEMA3A, ATG7 |
414 | GO:0030811 | 0.00 | 5.46 | 6.36 | 13 | 17 | regulation of nucleotide catabolic process | ARNT, GPD1, HIF1A, IGF1, INS, P2RX7, PGAM1, PRKAA1, PRKAG1, STAT3, OGT, HDAC4, RAPGEF3 |
415 | GO:0043267 | 0.00 | 5.46 | 6.36 | 13 | 17 | negative regulation of potassium ion transport | ATF4, CASQ2, CAV3, PTK2B, KCNE1, KCNH2, KCNQ1, SUMO1, VIP, KCNAB1, OXSR1, KCNE2, KCNE3 |
416 | GO:0046688 | 0.00 | 5.46 | 6.36 | 13 | 17 | response to copper ion | ALDOB, ATP5D, ATP7B, BAX, ICAM1, IL1A, LCAT, LIPC, PAM, S100A13, SNCA, SOD1, SORD |
417 | GO:0048016 | 0.00 | 5.46 | 6.36 | 13 | 17 | inositol phosphate-mediated signaling | RCAN1, EDN3, NRG1, HRH1, IGF1, ITPR1, ITPR2, PPP3R1, SLC9A1, SLC12A1, AKAP6, RCAN2, RCAN3 |
418 | GO:1900408 | 0.00 | 5.46 | 6.36 | 13 | 17 | negative regulation of cellular response to oxidative stress | ATF4, GPX1, HGF, HIF1A, HP, HSPB1, INS, PARK2, PSAP, PYCR1, SOD2, BAG5, TRAP1 |
419 | GO:1901522 | 0.00 | 5.46 | 6.36 | 13 | 17 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus | ATF4, RUNX2, DLX5, EP300, HIF1A, FOXA2, RBPJ, SMAD1, SMAD9, RXRA, RXRG, USF1, CREB3 |
420 | GO:0009725 | 0.00 | 5.43 | 43.49 | 91 | 122 | response to hormone | ABCA2, ABCA3, ACADS, ADRB2, AGXT, AK2, ALAD, ALDH3A1, ANG, ANXA3, APOA1, AVP, BAD, BAX, BCHE, CCND1, BCL2, BGLAP, BID, BMP6, BRCA2, TSPO, C3, CA2, CALCR, CBLB, CD4, CD38, CDK4, CDKN1A, CTNNA1, DHCR24, DNMT1, DTYMK, EEF2, ETS1, F3, PTK2B, FGA, GRN, HCLS1, HNMT, IDH1, IHH, IL1RN, KCNJ11, KRT19, LCAT, LDHA, SMAD6, NTRK3, OGG1, TNFRSF11B, OXCT1, PAM, PENK, PSPH, PTAFR, PTEN, PTGS1, PTN, S100B, SFRP4, SLC9A3, SNRPN, SORD, SRF, AURKA, TAC1, TACR3, TAT, TSHB, TUB, TYMS, UCN, SCGB1A1, TRIM25, PRDM2, FOSL1, ADAM9, ALDH1A2, MBD4, ABCG1, KEAP1, PDCD7, CITED2, PIAS3, SLC34A2, TXNIP, GPR83, SOX30 |
421 | GO:0070098 | 0.00 | 5.43 | 14.21 | 29 | 38 | chemokine-mediated signaling pathway | CCR3, CCR5, CCR8, ACKR2, CX3CR1, PTK2B, CCR10, XCR1, GPR17, CXCL1, CXCL3, HIF1A, PF4, PF4V1, CCL20, CCL21, CCL22, CCL24, CCL25, CXCL6, CXCL5, XCL1, CX3CL1, SLIT3, XCL2, SLIT2, CXCL13, CXCR6, CCR9 |
422 | GO:0032869 | 0.00 | 5.41 | 10.70 | 22 | 29 | cellular response to insulin stimulus | ALDOB, APRT, CDK2, GHRHR, GHSR, GOT1, HIF1A, HMGCS2, IGF1, PRKCI, RAB13, RXRA, SRSF5, SLC2A4, SLC9A1, SRD5A1, STAR, USF1, KAT2B, RAB10, RAB31, CAPN10 |
423 | GO:0014070 | 0.00 | 5.40 | 71.83 | 148 | 198 | response to organic cyclic compound | ABCA2, ABCA3, ACADS, ADM, ADRB2, ADSS, AGXT, ALDH3A1, ALDOB, ANGPT2, ANXA3, ANXA7, BIRC2, APOA1, AREG, STS, ATP12A, ATP7B, BID, BMP6, BRCA2, BSG, TSPO, C3, CA2, CALCR, CALM1, CALM3, CALU, CASP1, CD4, CD36, CD38, CDK2, CDK4, CDKN1A, CDO1, CCR5, COMT, CTGF, CTSV, DGKQ, DDX1, DHFR, DNMT1, DTYMK, DUSP1, EDNRA, ETS1, F3, F7, ACSL1, ACSL3, GATA4, GATA6, KAT2A, GNAL, GOT1, GRN, HLCS, ICAM1, IDH1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGFBP2, IHH, IL1RN, JUN, JUND, KCNC2, KCNJ8, KRAS, KRT19, LCAT, LDHA, LIPC, LUM, SMAD6, CITED1, NTRK3, TNFRSF11B, OTC, P2RX1, P2RX3, P2RX5, PAM, PAX4, PFKFB1, PLN, PPP2R2A, PRKAA1, PRKACB, PRKAR2B, PRKCE, PRKCQ, PSMB2, PSPH, PTEN, PTGER2, PTGER4, PTGS1, PTPRN, ABCD3, PYGM, S100B, SDC2, SELL, SELP, SLC9A3, SLIT3, SPARC, SREBF1, STAT5B, AURKA, TAC1, TAF2, TAT, TRPC3, TSHB, TYR, UCN, SCGB1A1, TRIM25, PRDM2, FOSL1, PEA15, ADAM9, RIPK2, ALDH1A2, MBD4, KYNU, TRPA1, SOCS3, DDX21, SLIT2, SLC22A6, EIF4A3, PDCD7, RAMP2, CITED2, SLC34A2, TXNIP, GPR83, SOX30 |
424 | GO:0071377 | 0.00 | 5.29 | 10.85 | 22 | 29 | cellular response to glucagon stimulus | ADCY3, ADCY5, ADCY6, ADCY9, ARG1, ASS1, CPS1, GCG, GCGR, GLP1R, GNAS, GNB1, GNG3, GNG10, GNG11, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, GLP2R |
425 | GO:0032870 | 0.00 | 5.19 | 15.53 | 32 | 43 | cellular response to hormone stimulus | ADRA2A, ASIP, AVPR1B, AVPR2, BBS2, BBS4, AKR1C4, DUSP1, ACSL1, FSHR, GATA4, GATA6, HMGCS1, IGFBP2, JUN, JUND, LIPC, OXTR, P2RY4, P2RY6, PRCP, PRKCE, PTGDR, PTGER2, PTGER4, SLC5A5, SLIT3, TNFSF4, PAX8, LATS1, SLIT2, RAMP2 |
426 | GO:0038093 | 0.00 | 5.15 | 13.30 | 27 | 36 | Fc receptor signaling pathway | ABL1, ACTB, ACTG1, CD3G, CDC42, FCGR1A, FCGR1B, FCGRT, FGR, HCK, HSP90AA1, HSP90AB1, LIMK1, PIGR, PRKCD, PRKCE, ELMO1, ABI1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, WASF2, BAIAP2, ARPC1A |
427 | GO:0031589 | 0.01 | 5.13 | 4.43 | 9 | 12 | cell-substrate adhesion | ANGPT1, EPHB1, GAS6, SMAD6, ATXN3, PRKX, RAC2, SORBS3, CORO1A |
428 | GO:0007623 | 0.00 | 5.10 | 13.39 | 27 | 36 | circadian rhythm | ATP7B, AVP, KLF9, CDK4, CRX, DDX5, DHX9, DYRK1A, EGR3, EP300, F7, JUN, JUND, LIPC, NTRK1, NTRK2, NTRK3, SERPINE1, PAX4, RPE65, SKP1, SLC9A3, SREBF1, TYMS, UBB, CUL1, PROKR1 |
429 | GO:0060401 | 0.00 | 5.09 | 26.93 | 54 | 72 | cytosolic calcium ion transport | ABL1, ATP1A2, BAX, BCL2, BMP4, CALM1, CALM3, CASQ1, CASQ2, CD4, CCR5, CTGF, CYBA, DDIT3, DIAPH1, EDNRA, F2, F2R, PTK2B, XCR1, GSTM2, HRC, HTR2C, IL13, ITPR1, ITPR2, NTSR1, P2RX3, P2RX4, P2RX5, P2RX7, PDE4D, PLN, PRKCE, PRKD1, PTPN6, RYR1, RYR2, RYR3, CCL21, XCL1, SLC8A3, SNCA, TRPC1, TRPC3, TRPM2, TRPV1, TRPA1, GSTO1, AKAP6, ATG5, TRDN, CHERP, CORO1A |
430 | GO:0071346 | 0.00 | 5.08 | 7.44 | 15 | 20 | cellular response to interferon-gamma | ASS1, CD58, DAPK3, EPRS, GAPDH, IL12B, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, STAR, XCL2 |
431 | GO:0030814 | 0.00 | 5.08 | 22.44 | 45 | 60 | regulation of cAMP metabolic process | ABCA1, ADM, ADRA2A, ADRB2, APLP1, AVP, AVPR2, CALCR, CALM1, CALM3, CRH, DRD3, DRD5, LPAR1, EDNRA, FSHR, GALR1, GCG, GHRH, GHRHR, GLP1R, GNAL, GNAS, GRM8, INSL3, NTRK1, NTRK2, P2RY11, PALM, PDE4D, PF4, PTGER4, PTHLH, RAF1, UCN, VIP, VIPR2, WFS1, AKAP6, GABBR2, AKAP12, CALCRL, RAMP2, RAPGEF3, CAP1 |
432 | GO:0030804 | 0.03 | 5.07 | 2.98 | 6 | 8 | positive regulation of cyclic nucleotide biosynthetic process | GUCA1A, GUCA1B, GUCA2A, GUCA2B, RCVRN, GUCA1C |
433 | GO:2000379 | 0.00 | 5.07 | 5.96 | 12 | 16 | positive regulation of reactive oxygen species metabolic process | AGTR1, TSPO, CD36, CDKN1A, GADD45A, F2, GRB2, SNCA, AKR1C3, RIPK1, RGN, RNF41 |
434 | GO:0097696 | 0.00 | 5.07 | 5.96 | 12 | 16 | STAT cascade | CSH1, GH2, PTPN1, PTPN6, STAT1, STAT2, STAT3, STAT4, STAT5B, ADAM17, CTR9, STAMBP |
435 | GO:0007254 | 0.00 | 5.07 | 5.96 | 12 | 16 | JNK cascade | CRKL, IRAK1, IRAK2, MAPK8, PTGER4, UBB, IKBKG, ARHGEF6, RB1CC1, SH2D3C, SH2D3A, TRIB1 |
436 | GO:0070555 | 0.00 | 5.06 | 5.96 | 12 | 16 | response to interleukin-1 | ANXA1, CD38, CYBA, ETS1, HNMT, IGBP1, CITED1, PRKCI, SELE, SNCA, RIPK2, HDAC4 |
437 | GO:1900182 | 0.00 | 5.06 | 5.96 | 12 | 16 | positive regulation of protein localization to nucleus | CCT6A, CDKN2A, FYN, INS, STK11, CCT3, OGT, EIF2AK3, CCT7, CCT4, CCT2, KAT7 |
438 | GO:0019229 | 0.00 | 5.06 | 7.46 | 15 | 20 | regulation of vasoconstriction | ADM, ADRA2A, AGTR1, ATP1A2, BDKRB2, BMPR2, CHRM1, CHRM3, ACE, EDN3, HIF1A, P2RX1, PRKCQ, CX3CL1, KCNMB2 |
439 | GO:0071482 | 0.00 | 5.06 | 10.45 | 21 | 28 | cellular response to light stimulus | CALM1, CALM3, CNGA1, CRY1, CRY2, GNAT1, GNB1, GNGT1, GUCA1A, GUCA1B, GUCY2F, GUCY2D, HIF1A, PDE6G, PRKCQ, RCVRN, RPGR, RS1, SAG, SLC24A1, GUCA1C |
440 | GO:0070252 | 0.00 | 5.06 | 16.46 | 33 | 44 | actin-mediated cell contraction | ATP1A1, ATP1A2, CAV3, DSC2, DSP, EMP2, GATA4, GJA5, KCNE1, KCNH2, KCNJ2, KCNQ1, PDE4B, PDE4D, PLN, RYR2, SCN4B, SCN5A, SLC9A1, STC1, TMOD1, TNNC2, TNNC1, TNNI2, TNNI3, TNNT1, TNNT2, TPM2, SUMO1, VIL1, VIM, NUP155, KCNE2 |
441 | GO:0044275 | 0.00 | 5.06 | 8.96 | 18 | 24 | cellular carbohydrate catabolic process | CALM1, CALM3, CPS1, G6PC, GAA, GK2, GPD2, PGM1, PHKA1, PHKA2, PHKB, PHKG1, PYGB, PYGL, PYGM, SORD, MGAM, TREH |
442 | GO:0007202 | 0.00 | 5.06 | 14.96 | 30 | 40 | activation of phospholipase C activity | ADCY3, ADCY5, ADCY6, ADCY9, ANG, ARHGAP6, AVPR1B, CALM1, CALM3, CAMK4, CREB1, LPAR1, EDNRA, GNA15, GNAQ, ITPR1, ITPR2, NTRK1, PDE1B, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCE, SELE, S1PR4, GPR55 |
443 | GO:0055078 | 0.00 | 5.05 | 7.47 | 15 | 20 | sodium ion homeostasis | AGTR1, AVP, AVPR2, COMT, DRD3, UTS2R, KNG1, PTGER4, SCN7A, SCNN1A, SCNN1B, SCNN1G, TAC1, UPK3A, CORIN |
444 | GO:0033555 | 0.00 | 5.05 | 7.47 | 15 | 20 | multicellular organismal response to stress | ADRA2A, BCL2, CCK, DBI, DPP4, EIF4E, EIF4G1, GABRA5, HMGCS2, HTR2C, IDO1, PENK, PTEN, RPS6KB1, DEAF1 |
445 | GO:0006809 | 0.03 | 5.05 | 2.98 | 6 | 8 | nitric oxide biosynthetic process | ARG2, TSPO, IGF1, IL10, PTGIS, RGN |
446 | GO:0050879 | 0.00 | 5.05 | 10.47 | 21 | 28 | multicellular organismal movement | ADRB2, ASCL1, ATP2A1, CACNA1A, CASQ1, CAV3, CHUK, DRD3, EEF2, GAA, GSTM2, ITPR1, KCNJ2, RPS6KB1, SLC8A3, TNNC2, TNNC1, TNNI2, TNNI3, TNNT1, GSTO1 |
447 | GO:0010633 | 0.04 | 5.05 | 2.99 | 6 | 8 | negative regulation of epithelial cell migration | CD63, TACSTD2, PFN2, PTPRR, SEMA3A, STRAP |
448 | GO:0043502 | 0.01 | 5.04 | 4.48 | 9 | 12 | regulation of muscle adaptation | CASQ1, GTF2I, IGFBP5, RPS6KB1, SCN5A, TNNC1, TNNT1, KLF4, HDAC4 |
449 | GO:0009712 | 0.00 | 5.04 | 8.98 | 18 | 24 | catechol-containing compound metabolic process | ABAT, AGTR2, AOC2, CHRNB2, COMT, DBH, DRD3, GRIN2A, HPRT1, PAH, PARK2, PDE1B, SNCB, SNCA, SULT1A1, SULT1A3, TACR3, SNCAIP |
450 | GO:0033683 | 0.00 | 5.04 | 8.98 | 18 | 24 | nucleotide-excision repair, DNA incision | DDB2, ERCC1, ERCC3, ERCC4, ERCC5, NTHL1, OGG1, PCNA, RFC3, RFC4, RFC5, RPA2, RPA3, UBB, XPA, CUL4A, CHD1L, RBX1 |
451 | GO:0042220 | 0.00 | 5.04 | 8.98 | 18 | 24 | response to cocaine | ABAT, ADRA1B, BAX, CHRNB2, CNR1, CRH, CRHBP, DNM2, DNMT3B, DRD3, DRD5, PTK2B, HNMT, HTR3A, OXTR, SNCA, TACR3, EFTUD2 |
452 | GO:0051290 | 0.00 | 5.04 | 8.98 | 18 | 24 | protein heterotetramerization | RRM1, RRM2, S100A10, HIST1H4I, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HIST1H3F |
453 | GO:0071870 | 0.01 | 5.04 | 4.48 | 9 | 12 | cellular response to catecholamine stimulus | ABL1, ADCY6, APLP1, APP, DNM2, DRD5, GNAS, GNB1, PARK2 |
454 | GO:0042417 | 0.04 | 5.04 | 2.99 | 6 | 8 | dopamine metabolic process | AGTR2, DBH, DRD3, GRIN2A, SNCB, SNCAIP |
455 | GO:0022400 | 0.00 | 5.04 | 7.48 | 15 | 20 | regulation of rhodopsin mediated signaling pathway | CALM1, CALM3, CNGA1, GNAT1, GNB1, GNGT1, GUCA1A, GUCA1B, GUCY2F, GUCY2D, PDE6G, PRKCQ, RCVRN, SAG, GUCA1C |
456 | GO:0010288 | 0.01 | 5.04 | 4.48 | 9 | 12 | response to lead ion | APP, CAT, CDK4, CPOX, PPP5C, QDPR, SLC34A1, SPARC, STAR |
457 | GO:0006312 | 0.04 | 5.04 | 2.99 | 6 | 8 | mitotic recombination | ERCC1, RAD51C, RAD51B, RAD51D, XRCC2, RAD50 |
458 | GO:0051489 | 0.04 | 5.04 | 2.99 | 6 | 8 | regulation of filopodium assembly | ARF6, CAPZB, CDC42, PRKCD, RAB5A, NRXN1 |
459 | GO:0002828 | 0.00 | 5.04 | 5.98 | 12 | 16 | regulation of type 2 immune response | ANXA1, CD86, ECM1, HLX, IFNA2, IDO1, PRKCZ, RARA, XCL1, STAT6, TNFSF4, IL27RA |
460 | GO:0018146 | 0.00 | 5.04 | 5.98 | 12 | 16 | keratan sulfate biosynthetic process | B4GALT1, LUM, CHST6, OMD, OGN, B4GALT4, B4GALT3, B4GALT6, B4GALT5, B3GNT3, SLC35D2, KERA |
461 | GO:0038084 | 0.00 | 5.04 | 5.98 | 12 | 16 | vascular endothelial growth factor signaling pathway | CD63, DCN, FLT1, FLT3, FLT4, HRG, HSPB1, KDR, PRKD1, NRP2, NRP1, ADAMTS3 |
462 | GO:0043552 | 0.00 | 5.04 | 5.98 | 12 | 16 | positive regulation of phosphatidylinositol 3-kinase activity | CDC42, EPHA8, PTK2B, FGFR3, FGR, FLT1, FLT3, KIT, PTK2, RAC1, CCL21, VAV3 |
463 | GO:0086091 | 0.00 | 5.04 | 5.98 | 12 | 16 | regulation of heart rate by cardiac conduction | DSC2, DSP, GJA5, KCNE1, KCNH2, KCNJ2, KCNQ1, SCN4B, SCN5A, KCNE2, HCN4, AKAP9 |
464 | GO:0002544 | 0.01 | 5.03 | 4.49 | 9 | 12 | chronic inflammatory response | AHCY, CX3CR1, IL1B, IL10, IDO1, S100A8, TNFAIP3, VCAM1, CXCL13 |
465 | GO:0006361 | 0.01 | 5.03 | 4.49 | 9 | 12 | transcription initiation from RNA polymerase I promoter | CCNH, ERCC3, TBP, TTF1, UBTF, KAT2B, TAF1C, TAF1B, TAF1A |
466 | GO:0007250 | 0.01 | 5.03 | 4.49 | 9 | 12 | activation of NF-kappaB-inducing kinase activity | IRAK1, TRAF2, IKBKG, TNFRSF10B, TNFRSF10A, TRAF4, TNFSF15, MALT1, COPS8 |
467 | GO:0010592 | 0.01 | 5.03 | 4.49 | 9 | 12 | positive regulation of lamellipodium assembly | DNM2, RAC1, RAC2, FSCN1, CLRN1, WNT1, HDAC4, ARPC2, WASF2 |
468 | GO:0010743 | 0.01 | 5.03 | 4.49 | 9 | 12 | regulation of macrophage derived foam cell differentiation | ABCA1, AGTR1, ALOX15B, CD36, CRP, ITGAV, PF4, NR1H2, ABCG1 |
469 | GO:0010971 | 0.01 | 5.03 | 4.49 | 9 | 12 | positive regulation of G2/M transition of mitotic cell cycle | APP, CCND1, CDK4, PBX1, RAD51C, RAD51B, SMARCD3, RAB11A, PHOX2B |
470 | GO:0014059 | 0.01 | 5.03 | 4.49 | 9 | 12 | regulation of dopamine secretion | ABAT, CHRNB2, CNR1, DRD3, KCNA2, PARK2, PCP4, SLC18A1, SNCA |
471 | GO:0032469 | 0.01 | 5.03 | 4.49 | 9 | 12 | endoplasmic reticulum calcium ion homeostasis | APP, ATP2A1, BAX, BCL2, GRINA, ITPR1, PSEN1, RAP1GDS1, WFS1 |
472 | GO:0032731 | 0.01 | 5.03 | 4.49 | 9 | 12 | positive regulation of interleukin-1 beta production | CASP1, CASP5, HSPB1, IFI16, IFNG, ISL1, SMAD3, P2RX7, TRIM16 |
473 | GO:0034377 | 0.01 | 5.03 | 4.49 | 9 | 12 | plasma lipoprotein particle assembly | ABCA1, APOA1, ARF1, ACSL3, LCAT, NR1H2, SOAT2, DGAT1, ABCA7 |
474 | GO:0042276 | 0.01 | 5.03 | 4.49 | 9 | 12 | error-prone translesion synthesis | PCNA, REV3L, RFC3, RFC4, RFC5, RPA2, RPA3, UBB, MAD2L2 |
475 | GO:0048070 | 0.01 | 5.03 | 4.49 | 9 | 12 | regulation of developmental pigmentation | BAX, BCL2, EDN3, GNAQ, IHH, KIT, KITLG, ZEB2, BCL2L11 |
476 | GO:0090322 | 0.01 | 5.03 | 4.49 | 9 | 12 | regulation of superoxide metabolic process | CD36, CRP, CYBA, DHFR, F2RL1, PRKCD, SOD1, RGN, FBLN5 |
477 | GO:1901017 | 0.01 | 5.03 | 4.49 | 9 | 12 | negative regulation of potassium ion transmembrane transporter activity | CASQ2, CAV3, KCNE1, KCNQ1, SUMO1, KCNAB1, OXSR1, KCNE2, KCNE3 |
478 | GO:1901881 | 0.01 | 5.03 | 4.49 | 9 | 12 | positive regulation of protein depolymerization | CFL2, F2RL1, SLN, SPAST, VIL1, SYNJ1, SEMA5A, KATNB1, STMN2 |
479 | GO:0000097 | 0.04 | 5.03 | 2.99 | 6 | 8 | sulfur amino acid biosynthetic process | AHCY, BHMT, CBS, CDO1, CTH, GOT1 |
480 | GO:0002664 | 0.04 | 5.03 | 2.99 | 6 | 8 | regulation of T cell tolerance induction | CBLB, CD3E, CD86, CLC, IL2RA, IDO1 |
481 | GO:0003188 | 0.04 | 5.03 | 2.99 | 6 | 8 | heart valve formation | EFNA1, ERG, GJA5, SOX9, TWIST1, DCHS1 |
482 | GO:0005513 | 0.04 | 5.03 | 2.99 | 6 | 8 | detection of calcium ion | CALM1, CALM3, CASQ2, RYR2, SYT1, KCNMB2 |
483 | GO:0006000 | 0.04 | 5.03 | 2.99 | 6 | 8 | fructose metabolic process | ALDOB, ALDOC, KHK, PFKFB1, PFKFB2, SORD |
484 | GO:0006012 | 0.04 | 5.03 | 2.99 | 6 | 8 | galactose metabolic process | GALE, GALK1, GALK2, B4GALT1, GLB1, PGM1 |
485 | GO:0007184 | 0.04 | 5.03 | 2.99 | 6 | 8 | SMAD protein import into nucleus | BMP4, BMP6, BMPR1A, DAB2, JUN, ZFYVE9 |
486 | GO:0007494 | 0.04 | 5.03 | 2.99 | 6 | 8 | midgut development | ASS1, CPS1, HMGCS2, OTC, RXRA, ALDH1A2 |
487 | GO:0010669 | 0.04 | 5.03 | 2.99 | 6 | 8 | epithelial structure maintenance | CXADR, SLC22A5, SOX9, SRF, CROCC, STRAP |
488 | GO:0010820 | 0.04 | 5.03 | 2.99 | 6 | 8 | positive regulation of T cell chemotaxis | ADAM10, S100A7, XCL1, ADAM17, TNFSF14, CXCL13 |
489 | GO:0014741 | 0.04 | 5.03 | 2.99 | 6 | 8 | negative regulation of muscle hypertrophy | CAV3, IGFBP5, P2RX4, RGS2, AKAP1, CTDP1 |
490 | GO:0014912 | 0.04 | 5.03 | 2.99 | 6 | 8 | negative regulation of smooth muscle cell migration | IGFBP3, IGFBP5, ILK, SERPINE1, SLIT2, TRIB1 |
491 | GO:0021794 | 0.04 | 5.03 | 2.99 | 6 | 8 | thalamus development | CHRNB2, OGDH, PTN, SRD5A1, TAL2, OLIG2 |
492 | GO:0030238 | 0.04 | 5.03 | 2.99 | 6 | 8 | male sex determination | NR0B1, IGF1R, INSRR, PTGDR, SOX9, SRY |
493 | GO:0030889 | 0.04 | 5.03 | 2.99 | 6 | 8 | negative regulation of B cell proliferation | ATM, PRDM1, CDKN2A, CTLA4, IL10, PAWR |
494 | GO:0031581 | 0.04 | 5.03 | 2.99 | 6 | 8 | hemidesmosome assembly | DST, CD151, COL17A1, ITGB4, KRT5, LAMA3 |
495 | GO:0032025 | 0.04 | 5.03 | 2.99 | 6 | 8 | response to cobalt ion | ALAD, BNIP3, CASP9, HIF1A, HMBS, SERPINF1 |
496 | GO:0032310 | 0.04 | 5.03 | 2.99 | 6 | 8 | prostaglandin secretion | ACSL4, IL1B, P2RX4, P2RX7, P2RY2, ABCC4 |
497 | GO:0033083 | 0.04 | 5.03 | 2.99 | 6 | 8 | regulation of immature T cell proliferation | BMP4, CDKN2A, ERBB2, IHH, IL1B, RIPK2 |
498 | GO:0033127 | 0.04 | 5.03 | 2.99 | 6 | 8 | regulation of histone phosphorylation | ATM, CCNB1, CDK9, IL1B, TWIST1, RPS6KA4 |
499 | GO:0036037 | 0.04 | 5.03 | 2.99 | 6 | 8 | CD8-positive, alpha-beta T cell activation | BCL2, TNFSF8, IFNG, IRF1, SATB1, XCL1 |
500 | GO:0042832 | 0.04 | 5.03 | 2.99 | 6 | 8 | defense response to protozoan | BCL3, CD37, IFNG, IL10, IL12B, SLC11A1 |
501 | GO:0043312 | 0.04 | 5.03 | 2.99 | 6 | 8 | neutrophil degranulation | ANXA3, BCR, PTAFR, STXBP2, STXBP3, STX11 |
502 | GO:0043517 | 0.04 | 5.03 | 2.99 | 6 | 8 | positive regulation of DNA damage response, signal transduction by p53 class mediator | ATM, ATR, CDKN2A, DDX5, HIC1, EEF1E1 |
503 | GO:0045717 | 0.04 | 5.03 | 2.99 | 6 | 8 | negative regulation of fatty acid biosynthetic process | ACADL, ACADVL, BRCA1, INSIG1, ERLIN1, ERLIN2 |
504 | GO:0046541 | 0.04 | 5.03 | 2.99 | 6 | 8 | saliva secretion | AQP5, CHRM1, CHRM3, KCNN4, TAC1, TRPC1 |
505 | GO:0046689 | 0.04 | 5.03 | 2.99 | 6 | 8 | response to mercury ion | ALAD, ALB, BSG, PGAM2, SLC34A1, TAT |
506 | GO:0046716 | 0.04 | 5.03 | 2.99 | 6 | 8 | muscle cell cellular homeostasis | CAV3, CFL2, GAA, HIF1A, SOD1, SRF |
507 | GO:0048935 | 0.04 | 5.03 | 2.99 | 6 | 8 | peripheral nervous system neuron development | HOXD9, HOXD10, ISL1, NTRK2, TBCE, ONECUT2 |
508 | GO:0051645 | 0.04 | 5.03 | 2.99 | 6 | 8 | Golgi localization | CDC42, STK11, UVRAG, YWHAZ, SLC9A3R1, STK25 |
509 | GO:0051775 | 0.04 | 5.03 | 2.99 | 6 | 8 | response to redox state | ADH5, ARHGDIB, ARNTL, RYR2, CLOCK, RNF7 |
510 | GO:0051969 | 0.04 | 5.03 | 2.99 | 6 | 8 | regulation of transmission of nerve impulse | AVP, CHRNB4, GLRA1, IFNG, PAWR, TNR |
511 | GO:0055012 | 0.04 | 5.03 | 2.99 | 6 | 8 | ventricular cardiac muscle cell differentiation | CCNB1, NRG1, RARA, RARB, RXRA, ATG5 |
512 | GO:0060433 | 0.04 | 5.03 | 2.99 | 6 | 8 | bronchus development | BMP4, IL13, SOX9, SRF, TULP3, ADAMTSL2 |
513 | GO:0060544 | 0.04 | 5.03 | 2.99 | 6 | 8 | regulation of necroptotic process | BIRC2, BIRC3, RIPK1, CFLAR, ARHGEF2, RBCK1 |
514 | GO:0060707 | 0.04 | 5.03 | 2.99 | 6 | 8 | trophoblast giant cell differentiation | PRDM1, GJB5, SNAI1, NR2F2, SOCS3, HAND1 |
515 | GO:0060736 | 0.04 | 5.03 | 2.99 | 6 | 8 | prostate gland growth | ESR1, IGF1, PSAP, PTEN, SOX9, UBE3A |
516 | GO:0061440 | 0.04 | 5.03 | 2.99 | 6 | 8 | kidney vasculature development | ANGPT1, ANGPT2, BMP4, HES1, SERPINB7, NRP1 |
517 | GO:0070307 | 0.04 | 5.03 | 2.99 | 6 | 8 | lens fiber cell development | CRYGB, EPHA2, FGFR3, TMOD1, VIM, BFSP2 |
518 | GO:0071157 | 0.04 | 5.03 | 2.99 | 6 | 8 | negative regulation of cell cycle arrest | CCND1, CDK4, CDK9, SETMAR, PHOX2B, CHEK2 |
519 | GO:0071498 | 0.04 | 5.03 | 2.99 | 6 | 8 | cellular response to fluid shear stress | ASS1, CA2, PTK2B, HDAC3, KLF4, KLF2 |
520 | GO:0090399 | 0.04 | 5.03 | 2.99 | 6 | 8 | replicative senescence | ATM, ATR, CDKN1A, CDKN2A, CHEK1, CHEK2 |
521 | GO:0097421 | 0.04 | 5.03 | 2.99 | 6 | 8 | liver regeneration | ADRB2, FGA, KLKB1, SRSF5, RGN, RAPGEF3 |
522 | GO:1901018 | 0.04 | 5.03 | 2.99 | 6 | 8 | positive regulation of potassium ion transmembrane transporter activity | ATP1B3, DNM2, AKAP7, AKAP6, AKAP9, RAPGEF3 |
523 | GO:1903427 | 0.04 | 5.03 | 2.99 | 6 | 8 | negative regulation of reactive oxygen species biosynthetic process | TSPO, IL10, PTGIS, STAT3, RGN, TRAP1 |
524 | GO:0032496 | 0.00 | 5.02 | 34.92 | 70 | 94 | response to lipopolysaccharide | ADH5, ADM, ALAD, ATP4B, BCR, CASP1, CASP9, TNFRSF8, CHUK, CNP, CNR1, CNR2, COMT, CPS1, DCN, DNMT1, EDNRA, F2R, F3, CXCL1, CXCL3, IGF1, IL10RA, IL12RB2, IL13, IDO1, JUN, JUND, KCNJ8, CITED1, TNFRSF11B, P2RX7, PAWR, PENK, PF4, PF4V1, EIF2AK2, PTGER1, PTGER2, PTGER4, RPS6KB1, S100A7, S100A8, CXCL6, CXCL5, SELE, SELP, SLC11A1, SLPI, SNCA, SPARC, STAT5B, ABCC8, TAC1, ADAM17, TNFRSF1A, TNFRSF4, SCGB1A1, VCAM1, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, SOCS3, NR1H4, IL18BP, CXCL13, GJB6, PRDX3 |
525 | GO:0042493 | 0.00 | 4.97 | 76.09 | 151 | 204 | response to drug | ABAT, ABCA1, ABCA2, ABCA3, PARP4, AK4, ALAD, ALDH3A1, ALDOB, ANXA1, APOA1, ARG1, ASS1, ATP1A1, ATP1A3, ATP4A, ATR, BAD, BAX, BCHE, CCND1, BCL2, BDKRB2, BGLAP, TSPO, CAT, CCNB1, CCNE1, CD86, CD38, CDH1, CDH3, CDK2, CDK4, CDK9, CDKN1A, CENPF, CHAT, CHUK, COL1A1, COMT, CPS1, CREB1, CRH, CTPS1, CYBA, CYP2A6, CYP3A4, DAD1, DDIT3, DNMT1, DNMT3B, DRD3, EEF2, EMX1, EMX2, ENO3, ACSL1, PTK2B, FYN, GABRA4, GAD1, GAD2, GATA4, GATA6, GNAS, UTS2R, GRIN2A, HMBS, HMGCS1, HMGCS2, HNRNPD, HTR2C, ICAM1, IFNG, IGF2, IGFBP2, IL10, ITGA3, ITGB1, JUN, JUND, KCNJ11, KCNK3, LDHA, LIPC, MGMT, NTRK1, OGG1, TNFRSF11B, OTC, OXCT1, OXTR, P2RX7, PAM, PAX4, PDE3A, PFAS, ATP8B1, PRKAR2B, PTEN, PTGER4, PTN, PTPRM, ABCD3, RAD51, RPN2, RPS6KB1, SLC1A3, SLC6A11, SLC9A1, SLC15A2, SLC34A1, SLC18A1, SLC22A1, SLC22A3, SLC22A2, SLC22A5, SNCA, SOD1, SORD, SRD5A1, SREBF1, SRP14, SRP19, SRP68, STAR, STAT3, ABCC8, ADAM17, TOP1, TP73, TYMS, SCGB1A1, VEGFB, VEGFC, XPC, FOSL1, BCAR3, BECN1, GGH, TRPA1, SOCS3, ABCG2, ATG5, HDAC4, PEMT, VAV3, TXNIP, EBP, PAPD7 |
526 | GO:0042542 | 0.00 | 4.90 | 13.04 | 26 | 35 | response to hydrogen peroxide | AREG, BAD, BCL2, CAT, COL1A1, DDIT3, DUSP1, EEF2, PTK2B, GJA3, GPX1, HBA2, HP, JUN, KPNA4, LDHA, OLR1, PPP2CB, SHC1, SOD1, STAR, FOSL1, ADAM9, TRPA1, TXNIP, PRDX3 |
527 | GO:0014823 | 0.00 | 4.84 | 11.59 | 23 | 31 | response to activity | ADSL, AKT2, ALAD, ANGPT2, BGLAP, BMP6, CAT, CREB1, DNMT1, DNMT3B, HIF1A, IGF1, IL10, ITGB1, NTRK1, OXCT1, PCK1, PRKAA1, PTN, RYR2, SRD5A1, STAR, UQCRC1 |
528 | GO:0060443 | 0.00 | 4.80 | 10.10 | 20 | 27 | mammary gland morphogenesis | AREG, ARG1, BAX, BMP4, CAPN1, CAV3, CSF1R, EPHA2, ESR1, ETV4, ETV5, B4GALT1, IGFBP5, PAX3, PGR, PTHLH, SLC12A2, STAT6, SLIT2, NRG3 |
529 | GO:0032943 | 0.00 | 4.78 | 14.10 | 28 | 38 | mononuclear cell proliferation | ABL1, BAX, CCND3, CD151, CR2, CTPS1, ACE, FLT3, FYN, HPRT1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IMPDH1, IMPDH2, ITGAD, CD180, P2RX7, PRKCD, RAG2, SATB1, SLC11A1, TNFSF14, MALT1, BTN3A1 |
530 | GO:0070482 | 0.00 | 4.77 | 32.35 | 64 | 87 | response to oxygen levels | ABAT, ADM, ADSL, AHCY, ALAD, ALAS2, ALDH3A1, ANG, ANGPT2, APAF1, BIRC2, ASCL2, ATM, CASP1, CAT, CD38, CDK4, CDKN1A, CHAT, CHRNB2, COL1A1, CLDN3, CREB1, CTGF, DPP4, EDNRA, ERCC3, ETS1, PTK2B, FLT1, HMBS, IGF1, IL1B, ITPR1, ITPR2, LDHA, LIPC, SMAD3, SLC11A2, OXTR, P2RX3, PAM, PENK, PRKCQ, PYGM, RAF1, RYR1, RYR2, SCNN1B, CX3CL1, SDC2, SHC1, SRF, STAT5B, ADAM17, HSP90B1, TSC2, USF1, VCAM1, BECN1, SOCS3, PDLIM1, RAMP2, TACC3 |
531 | GO:0097192 | 0.00 | 4.77 | 8.59 | 17 | 23 | extrinsic apoptotic signaling pathway in absence of ligand | BAD, BAX, BCL2A1, BOK, CASP9, DAPK3, DCC, EYA2, IGF1, ITGAV, KITLG, PPP2R1A, PPP2R1B, SRPX, BAG3, BCL2L10, BCL2L11 |
532 | GO:1902656 | 0.00 | 4.76 | 22.81 | 45 | 61 | calcium ion import into cytosol | ABL1, ATP1A2, BAX, CALM1, CALM3, CASQ1, CASQ2, CCR5, CYBA, DDIT3, DIAPH1, EDNRA, F2, F2R, PTK2B, XCR1, GSTM2, HRC, HTR2C, IL13, ITPR1, ITPR2, NTSR1, P2RX7, PDE4D, PLN, PRKCE, PRKD1, PTPN6, RYR1, RYR2, RYR3, CCL21, XCL1, SNCA, TRPC1, TRPM2, TRPV1, TRPA1, GSTO1, AKAP6, ATG5, TRDN, CHERP, CORO1A |
533 | GO:0003014 | 0.00 | 4.74 | 7.07 | 14 | 19 | renal system process | ADRB2, BCL2, BMP4, CHRNB2, CHRNB4, KCNJ1, KCNQ1, PCSK5, SGK1, HNF1A, TRPV1, AKR1C3, SLC22A6, SLC9A3R1 |
534 | GO:1903779 | 0.00 | 4.72 | 14.20 | 28 | 38 | regulation of cardiac conduction | ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B3, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, CASQ1, CASQ2, CXADR, GJA5, ITPR1, ITPR2, KCNJ11, FXYD3, PLN, RYR1, RYR2, RYR3, SLC8A3, TNNI3, TRPC1, ABCC9, CORIN, AHCYL1 |
535 | GO:0010907 | 0.00 | 4.70 | 7.11 | 14 | 19 | positive regulation of glucose metabolic process | ADRA1B, AKT2, GCG, KAT2A, GPLD1, IGF1, IGF2, INS, DYRK2, KAT2B, RGN, EPM2AIP1, SORBS1, ARPP19 |
536 | GO:0032094 | 0.00 | 4.70 | 7.11 | 14 | 19 | response to food | BBS2, BBS4, CCK, CLPS, CPS1, GAST, G6PC, GCG, GHRH, GHSR, SLC16A1, SREBF1, UCN, SOCS3 |
537 | GO:0042517 | 0.00 | 4.70 | 7.11 | 14 | 19 | positive regulation of tyrosine phosphorylation of Stat3 protein | CNTF, CSF1R, CTF1, FGFR3, HES1, IFNA2, IL12B, IL15, IL18, ISL1, KIT, PTGER4, CRLF1, IL24 |
538 | GO:0050434 | 0.00 | 4.70 | 7.11 | 14 | 19 | positive regulation of viral transcription | CCNH, CCNT1, CDK9, CHD1, EP300, ERCC3, GTF2F1, JUN, SMARCA4, SP1, SSRP1, SUPT4H1, CTDP1, SUPT16H |
539 | GO:0007267 | 0.00 | 4.69 | 50.64 | 101 | 140 | cell-cell signaling | ADAM10, ADRA1B, AREG, ASIP, AVP, BMP3, BMP4, BST2, C1QA, CASQ2, CD80, CD86, TNFSF8, SIGLEC6, CD70, ADGRE5, CDC42, CGA, CCR5, CTF1, CTGF, CXADR, EFNA1, EFNA3, EFNA4, EFNB1, EREG, FGF3, FGF4, FGF5, FGF7, FGFR3, NR5A1, FZD2, GATA4, GJA3, GJA4, GJA5, GJB1, GRB2, GUCA1B, HGF, HES1, IAPP, IFNA2, IHH, IK, IL10, IL13, IL15, IL17A, IL18, INSL3, INSL4, NTF4, PCSK5, PGR, PHEX, PYY, PTHLH, RYR2, S100A9, SERPINB3, SCN4B, SCN5A, SCN10A, CCL20, CCL21, CCL22, CCL24, CXCL6, CXCL5, XCL1, SSTR2, KLF10, TNFAIP6, TSHB, VIPR2, WNT1, WNT2, WNT2B, SEMA3B, HMGA2, TP63, TNFSF10, TNFSF9, NRP1, WISP3, WISP1, TNFSF18, SEMA5A, GPR50, GRAP2, GDF15, CXCL14, NUP155, FGFBP1, CHST4, SEMA4F, CXCL13, GRAP |
540 | GO:0031295 | 0.00 | 4.68 | 12.72 | 25 | 34 | T cell costimulation | CD3D, CD3E, CD3G, CD4, CD5, CD28, CD80, CD86, CDC42, CTLA4, DPP4, EFNB1, FYN, GRB2, HLA-DQA1, PTPN6, RAC1, CCL21, SPN, TNFSF4, VAV1, TNFSF14, GRAP2, TNFSF13B, HHLA2 |
541 | GO:0001666 | 0.00 | 4.67 | 30.52 | 60 | 82 | response to hypoxia | ABAT, ADM, ADSL, AHCY, ALAD, ALAS2, ALDH3A1, ANG, ANGPT2, APAF1, BIRC2, ASCL2, ATM, CASP1, CAT, CD38, CHAT, CHRNB2, CLDN3, CREB1, DNMT3B, DPP4, EDNRA, ERCC3, ETS1, PTK2B, FLT1, HMBS, IGF1, IL1B, ITPR1, ITPR2, LDHA, LIPC, SMAD3, SLC11A2, P2RX3, PAM, PENK, PRKCQ, PYGM, RAF1, RYR1, RYR2, SCNN1B, CX3CL1, SDC2, SHC1, SRF, STAT5B, ADAM17, HSP90B1, TSC2, USF1, VCAM1, BECN1, SOCS3, PDLIM1, RAMP2, TACC3 |
542 | GO:0007204 | 0.00 | 4.66 | 44.44 | 87 | 119 | positive regulation of cytosolic calcium ion concentration | ABL1, ABL2, ADCY5, ADM, ADRA1B, ATP1A2, AVP, AVPR1B, BAX, BCL2, BDKRB2, BMP4, CACNA1A, CALCR, CALM1, CALM3, CASQ1, CASQ2, CAV3, CD4, CD36, CD38, CD52, CCR3, CCR5, CCR8, CYBA, DDIT3, DIAPH1, S1PR3, ESR1, F2, F2RL1, PTK2B, GALR1, GLP1R, GNA15, GNAT2, GNB1, GNG3, CCR10, XCR1, UTS2R, GSTM2, HRC, IL1B, IL13, ITPR1, ITPR2, KNG1, NTSR1, OXTR, P2RX3, P2RX4, P2RX5, P2RX7, P2RY1, P2RY2, P2RY4, PDE4D, PLN, PRKCE, PRKD1, PTPN6, RYR1, RYR2, RYR3, CCL21, XCL1, SLC8A3, SNCA, TAC1, TRPC1, TRPC3, TRPM2, TRPV1, S1PR4, TRPA1, GSTO1, AKAP6, ATG5, TRDN, CIB2, CHERP, CXCL13, CCR9, CORO1A |
543 | GO:0010517 | 0.00 | 4.65 | 22.44 | 44 | 60 | regulation of phospholipase activity | ABL1, ABL2, ADCY3, ADCY5, ADCY6, ADCY9, AGTR1, ANG, ANXA1, ARHGAP6, ARL1, AVPR1B, BICD1, CALM1, CALM3, CAMK4, CREB1, LPAR1, EDNRA, ESR1, FGFR3, FLT1, GNA15, GNAQ, ITPR1, ITPR2, KIT, NTRK1, PDE1B, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCE, PRKCZ, PTAFR, RGS2, SELE, SNCA, S1PR4, GPR55 |
544 | GO:0051209 | 0.00 | 4.65 | 5.58 | 11 | 15 | release of sequestered calcium ion into cytosol | DDIT3, XCR1, HTR2C, ITPR1, ITPR2, P2RX7, RYR3, CCL21, TRPV1, TRPA1, CHERP |
545 | GO:0034097 | 0.00 | 4.65 | 12.97 | 26 | 36 | response to cytokine | ADAM10, AVPR2, BCL2, BCL2L1, CCNE1, COL3A1, ACSL4, ITIH4, JUN, JUND, AFF3, OXTR, PGGT1B, RARA, RPS6KB1, SLC11A1, SPARC, SRF, TYMS, SCGB1A1, FOSL1, ADAM9, ALDH1A2, KYNU, TRAFD1, ADAMTS13 |
546 | GO:0038096 | 0.00 | 4.64 | 16.83 | 33 | 45 | Fc-gamma receptor signaling pathway involved in phagocytosis | ABL1, ACTB, ACTG1, CD3G, CDC42, FCGR1A, FGR, FYN, GRB2, HCK, HSP90AA1, HSP90AB1, ITPR1, ITPR2, LIMK1, PIK3CB, PRKCD, PRKCE, PTK2, RAC1, VAV1, ELMO1, ABI1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, WASF2, VAV3, BAIAP2, ARPC1A |
547 | GO:1901655 | 0.00 | 4.64 | 5.59 | 11 | 15 | cellular response to ketone | ADCY3, ADCY5, ATP2B1, KLF9, CDC5L, ELK1, GAS6, GNAI1, AIFM1, KLF4, KLF2 |
548 | GO:0048857 | 0.01 | 4.63 | 5.60 | 11 | 15 | neural nucleus development | ALDH1A3, PHOX2A, ASCL1, BCL2, CACNA1A, CHRNB2, KCNC1, KCNC2, PHOX2B, SLC4A7, SEC24B |
549 | GO:0001541 | 0.00 | 4.63 | 11.21 | 22 | 30 | ovarian follicle development | ANG, BAX, BCL2, BCL2L1, BMP4, CAPN5, CTNNA1, FANCF, FANCG, FGF7, FSHB, CENPI, FSHR, ICAM1, INHA, KDR, KIT, KITLG, SOD1, UBE3A, EIF2B2, EIF2B5 |
550 | GO:0010043 | 0.00 | 4.63 | 11.21 | 22 | 30 | response to zinc ion | ALAD, ALDOB, ARG1, ASS1, ATP7B, BGLAP, CA2, CPS1, HMBS, KHK, LTA4H, OTC, P2RX7, PLN, PTEN, S100A8, ABCC8, VCAM1, SLC30A2, SLC30A3, SLC30A4, GGH |
551 | GO:0003044 | 0.00 | 4.63 | 11.22 | 22 | 30 | regulation of systemic arterial blood pressure mediated by a chemical signal | ADRA1B, ADRB2, AGTR1, AGTR2, AVPR1B, AVPR2, CTSZ, CYBA, ACE, DRD3, DRD5, EDN3, F2R, F2RL1, GJA5, OXTR, PCSK5, PDE4D, SLC2A5, SOD2, ATP6AP2, CORIN |
552 | GO:0003151 | 0.00 | 4.63 | 11.22 | 22 | 30 | outflow tract morphogenesis | JAG1, ATF2, EYA1, FZD2, GATA6, GJA5, HIF1A, HES1, RBPJ, ILK, ISL1, JUN, RARA, RARB, RYR1, SIX1, SOX11, TWIST1, WNT11, DHRS3, CITED2, SEC24B |
553 | GO:0061180 | 0.01 | 4.63 | 5.60 | 11 | 15 | mammary gland epithelium development | AKT2, CAV3, CSF1R, ETV5, HIF1A, MGMT, PGR, PTHLH, SLC12A2, WNT2, SLIT2 |
554 | GO:0046686 | 0.01 | 4.62 | 5.61 | 11 | 15 | response to cadmium ion | ALAD, ARG1, CAT, CDK2, CYB5A, DTYMK, PCNA, MAPK8, SLC34A1, SORD, SPARC |
555 | GO:0001702 | 0.01 | 4.61 | 5.61 | 11 | 15 | gastrulation with mouth forming second | ACVR1, ACVR2A, ACVR2B, GATA4, HHEX, FOXA2, OTX2, SRF, UGDH, ZBTB17, CHRD |
556 | GO:0002026 | 0.01 | 4.61 | 5.61 | 11 | 15 | regulation of the force of heart contraction | ADM, ADRA1B, ADRB2, ATP1A1, ATP1A2, GAA, IFNG, PLN, RYR2, SLC9A1, CSRP3 |
557 | GO:0003197 | 0.01 | 4.61 | 5.61 | 11 | 15 | endocardial cushion development | ACVR1, JAG1, BMP4, BMPR1A, ERG, GATA4, RBPJ, ISL1, SOX9, TWIST1, DCHS1 |
558 | GO:0032007 | 0.01 | 4.61 | 5.61 | 11 | 15 | negative regulation of TOR signaling | ARNTL, ATM, CRYBA1, HIF1A, PRKAA1, STK11, TSC1, TSC2, EPM2A, MAPKAPK5, PDCD6 |
559 | GO:0034199 | 0.01 | 4.61 | 5.61 | 11 | 15 | activation of protein kinase A activity | ADCY3, ADCY5, ADCY6, ADCY9, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, UCN |
560 | GO:0035813 | 0.01 | 4.61 | 5.61 | 11 | 15 | regulation of renal sodium excretion | AGTR1, AGTR2, AVP, AVPR2, COMT, DRD3, UTS2R, KNG1, PTGER4, TAC1, CORIN |
561 | GO:0042776 | 0.01 | 4.61 | 5.61 | 11 | 15 | mitochondrial ATP synthesis coupled proton transport | ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP5O, ATP5J2, ATP5H, ATP5L |
562 | GO:0060669 | 0.01 | 4.61 | 5.61 | 11 | 15 | embryonic placenta morphogenesis | ADM, GJB5, GRB2, IL10, ITGA4, LLGL2, SPINT1, ST14, VCAM1, FZD5, SOCS3 |
563 | GO:0061615 | 0.01 | 4.61 | 5.61 | 11 | 15 | glycolytic process through fructose-6-phosphate | ALDOB, ALDOC, ENO2, ENO3, GAPDH, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PPP2R5D |
564 | GO:0061621 | 0.01 | 4.61 | 5.61 | 11 | 15 | canonical glycolysis | ALDOB, ALDOC, ENO2, ENO3, GAPDH, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PPP2R5D |
565 | GO:2000403 | 0.01 | 4.61 | 5.61 | 11 | 15 | positive regulation of lymphocyte migration | ADAM10, PTK2B, ITGA4, S100A7, CCL20, CCL21, XCL1, ADAM17, TNFSF14, CXCL14, CXCL13 |
566 | GO:1901617 | 0.00 | 4.61 | 9.66 | 19 | 26 | organic hydroxy compound biosynthetic process | ACADM, AGTR2, ALDH9A1, ALOX12, ASIP, CDH3, CTNS, DBH, LDHC, CITED1, PAH, SHMT1, TRPC1, TYR, TYRP1, BBOX1, PDXK, RAPGEF2, ZEB2 |
567 | GO:0051353 | 0.00 | 4.56 | 9.72 | 19 | 26 | positive regulation of oxidoreductase activity | ABL1, ABL2, AGTR1, AGTR2, CALM1, CALM3, CDH3, DHFR, ESR1, PTK2B, FCER2, HIF1A, IFNG, IL1B, INS, KRAS, SNCA, FGF23, RGN |
568 | GO:0033138 | 0.00 | 4.56 | 13.82 | 27 | 37 | positive regulation of peptidyl-serine phosphorylation | AKT2, ANGPT1, ARAF, AVP, BCL2, CD44, CDC42, CREBL2, GAS6, GCG, HCLS1, NTF3, NTRK2, NTRK3, PFN2, PRKD1, RAF1, SNCA, UCN, BCAR3, CAMK1, RIPK2, LATS1, BAG4, AKAP9, RAPGEF3, MAD2L2 |
569 | GO:1900371 | 0.00 | 4.55 | 22.05 | 43 | 59 | regulation of purine nucleotide biosynthetic process | ABCA1, ADM, ADRA2A, ADRB2, APLP1, AVP, AVPR2, CALCR, CALM1, CALM3, CRH, DRD3, DRD5, LPAR1, EDNRA, FSHR, GALR1, GCG, GHRH, GHRHR, GLP1R, GNAL, GNAS, GRM8, INSL3, NTRK1, NTRK2, P2RY11, PALM, PTGER4, PTHLH, RAF1, STAT3, UCN, VIP, VIPR2, WFS1, AKAP6, GABBR2, AKAP12, CALCRL, RAMP2, CAP1 |
570 | GO:0070301 | 0.00 | 4.55 | 13.84 | 27 | 37 | cellular response to hydrogen peroxide | ABL1, ANXA1, ARG1, BNIP3, ETS1, F3, HGF, HIF1A, MAP3K5, PPP5C, PRKAA1, PRKCD, MAPK8, PSAP, PYCR1, RPS3, STAT6, TNFAIP3, IL18RAP, AIFM1, KLF4, HDAC6, IL18BP, TRAP1, KLF2, STK25, ZNF277 |
571 | GO:0070911 | 0.00 | 4.55 | 13.84 | 27 | 37 | global genome nucleotide-excision repair | CCNH, DDB2, ERCC1, ERCC3, ERCC4, ERCC5, PCNA, RAD23B, RFC3, RFC4, RFC5, RPA2, RPA3, SUMO3, UBB, UBE2V2, SUMO1, XPA, XPC, CUL4A, COPS3, COPS2, CHD1L, RBX1, COPS8, COPS6, COPS5 |
572 | GO:0071320 | 0.00 | 4.55 | 13.84 | 27 | 37 | cellular response to cAMP | APP, ASS1, HCN2, CFTR, CPS1, CRHBP, GPD1, RAPGEF1, IGFBP5, ITPR2, KCNE1, KCNQ1, PDE4D, PENK, PTAFR, SLC5A5, SLC8A3, SRD5A1, STAR, STC1, AKAP1, AKAP7, AKAP6, RAPGEF2, HCN4, AKAP9, RAPGEF3 |
573 | GO:0010950 | 0.02 | 4.51 | 4.09 | 8 | 11 | positive regulation of endopeptidase activity | PSME1, PSME2, SERPINB3, SEMG1, PICALM, PSME3, PSMD14, ADRM1 |
574 | GO:0002687 | 0.02 | 4.50 | 4.10 | 8 | 11 | positive regulation of leukocyte migration | ICAM1, KITLG, PTAFR, CCL24, SELE, SELP, MADCAM1, TNFRSF18 |
575 | GO:1901216 | 0.02 | 4.49 | 4.10 | 8 | 11 | positive regulation of neuron death | ABL1, BAD, CLU, ELK1, MAP3K5, TRPM2, AIMP2, PICALM |
576 | GO:0042312 | 0.02 | 4.49 | 4.10 | 8 | 11 | regulation of vasodilation | ADCY6, AGTR1, CRP, ACE, UTS2R, HMGCR, P2RY1, P2RY2 |
577 | GO:0098657 | 0.00 | 4.49 | 8.22 | 16 | 22 | import into cell | DRD3, GFAP, GLUL, ITGA4, KCNJ10, NTSR1, PARK2, PAWR, RAB3B, SLC1A3, SLC8A3, SLC18A1, SLC22A3, SNAP25, SNCA, PICALM |
578 | GO:0030195 | 0.02 | 4.49 | 4.11 | 8 | 11 | negative regulation of blood coagulation | ABAT, ADRB2, ALOX12, ANXA5, KNG1, PRKCD, PROC, VTN |
579 | GO:0003300 | 0.02 | 4.48 | 4.11 | 8 | 11 | cardiac muscle hypertrophy | AGTR2, GATA4, GATA6, RYR2, CSRP3, SORBS2, KDM4A, HDAC4 |
580 | GO:0006734 | 0.00 | 4.48 | 8.23 | 16 | 22 | NADH metabolic process | ALDOB, ALDOC, ENO2, ENO3, GAPDH, GPD1, LDHA, MDH1, MDH2, OGDH, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PPP2R5D |
581 | GO:0042730 | 0.02 | 4.48 | 4.11 | 8 | 11 | fibrinolysis | SERPING1, FAP, FGA, FGG, GP1BA, KLKB1, KRT1, SERPINB2 |
582 | GO:0009084 | 0.02 | 4.48 | 4.11 | 8 | 11 | glutamine family amino acid biosynthetic process | GLS, GLUD1, GLUL, OAT, PYCR1, ALDH18A1, SLC1A3, ALDH4A1 |
583 | GO:0002888 | 0.02 | 4.47 | 4.11 | 8 | 11 | positive regulation of myeloid leukocyte mediated immunity | C3, F2RL1, FCER1G, FGR, IL13, PTAFR, VAMP8, GAB2 |
584 | GO:0006298 | 0.02 | 4.47 | 4.11 | 8 | 11 | mismatch repair | ABL1, PCNA, RPA2, RPA3, TP73, XPC, EXO1, RNASEH2A |
585 | GO:0010460 | 0.02 | 4.47 | 4.11 | 8 | 11 | positive regulation of heart rate | ADM, ADRA1B, EDN3, HRC, KCNQ1, PDE4D, RYR2, TACR3 |
586 | GO:0018298 | 0.02 | 4.47 | 4.11 | 8 | 11 | protein-chromophore linkage | AMBP, OPN1SW, CRY1, CRY2, OPN1MW, OPN1LW, RGR, RRH |
587 | GO:0031646 | 0.02 | 4.47 | 4.11 | 8 | 11 | positive regulation of neurological system process | CHRNB4, HGF, NRG1, P2RX3, PAWR, PTAFR, TNR, RNF10 |
588 | GO:0033141 | 0.02 | 4.47 | 4.11 | 8 | 11 | positive regulation of peptidyl-serine phosphorylation of STAT protein | GFRA2, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1 |
589 | GO:0034047 | 0.02 | 4.47 | 4.11 | 8 | 11 | regulation of protein phosphatase type 2A activity | IGBP1, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, EIF2AK2, SET, ARPP19 |
590 | GO:0036065 | 0.02 | 4.47 | 4.11 | 8 | 11 | fucosylation | FUT6, FUT8, CFP, SPON1, FUT9, ADAMTS13, ADAMTS5, ADAMTS7 |
591 | GO:0042359 | 0.02 | 4.47 | 4.11 | 8 | 11 | vitamin D metabolic process | CYP3A4, CYP24A1, GFI1, IFNG, IL1B, SNAI1, CUBN, FGF23 |
592 | GO:0043084 | 0.02 | 4.47 | 4.11 | 8 | 11 | penile erection | ACVR2A, AVP, CNR1, EDNRA, OXTR, P2RY1, P2RY2, VIP |
593 | GO:0051968 | 0.02 | 4.47 | 4.11 | 8 | 11 | positive regulation of synaptic transmission, glutamatergic | PTK2B, GLUL, NTRK1, NTRK2, OXTR, RELN, TNR, NRXN1 |
594 | GO:0055025 | 0.02 | 4.47 | 4.11 | 8 | 11 | positive regulation of cardiac muscle tissue development | BMP4, CCNB1, GATA4, GATA6, NRG1, RBPJ, WNT2, AKAP6 |
595 | GO:0060444 | 0.02 | 4.47 | 4.11 | 8 | 11 | branching involved in mammary gland duct morphogenesis | AREG, CAV3, EPHA2, ESR1, ETV4, ETV5, PGR, SLC12A2 |
596 | GO:0060914 | 0.02 | 4.47 | 4.11 | 8 | 11 | heart formation | BMP4, BMPR1A, EYA1, HES1, RBPJ, ISL1, SIX1, SMARCD3 |
597 | GO:0097205 | 0.02 | 4.47 | 4.11 | 8 | 11 | renal filtration | EDNRA, EMP2, F2R, F2RL1, GAS6, GJA5, UTS2R, ITGA3 |
598 | GO:1902176 | 0.02 | 4.47 | 4.11 | 8 | 11 | negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | GPX1, HIF1A, HSPB1, INS, PARK2, SOD2, BAG5, TRAP1 |
599 | GO:0032868 | 0.00 | 4.44 | 9.19 | 18 | 25 | response to insulin | ADM, CAT, CRY1, EGR2, IL10, INPPL1, KHK, CITED1, OTC, PCK1, PFKFB1, PLN, PTPRN, SORT1, STXBP3, ABCC8, GGH, EPM2AIP1 |
600 | GO:0001938 | 0.00 | 4.44 | 14.96 | 29 | 40 | positive regulation of endothelial cell proliferation | ACVRL1, ANG, ARG1, ARNT, BMP4, BMP6, BMPR2, CAV2, CCR3, CYBA, ECM1, EGR3, F3, FGFR3, FLT4, HIF1A, NR4A1, JUN, KDR, PRKD1, CCL24, VEGFB, VIP, WNT2, SCG2, NRP2, NRP1, SEMA5A, PDCD6 |
601 | GO:0048511 | 0.00 | 4.43 | 9.21 | 18 | 25 | rhythmic process | ADRB2, ANXA1, AXL, CLU, CSNK2A1, EGR2, ETS1, HLF, OXTR, SERPINF1, PTN, SP1, TRPM2, TWIST1, TYRO3, KDM5C, KAT2B, ENOX2 |
602 | GO:0007569 | 0.00 | 4.43 | 10.83 | 21 | 29 | cell aging | ARNTL, BCL2, BGLAP, BMPR1A, BRCA2, ERCC1, HSD17B10, HMGA1, ICAM1, ILK, ING2, OPA1, SERPINE1, PRKCD, SOD1, SRF, HMGA2, MAPKAPK5, EEF1E1, NUAK1, ZNF277 |
603 | GO:0071345 | 0.00 | 4.43 | 7.60 | 15 | 21 | cellular response to cytokine stimulus | CD86, CDC5L, CDK9, DPYSL3, ETV3, FGA, HCLS1, HMBS, IL13, ITGA4, PDE1B, SELPLG, FGF23, IL18RAP, AKAP6 |
604 | GO:0046660 | 0.00 | 4.42 | 24.31 | 47 | 65 | female sex differentiation | AMHR2, ANG, AXL, BAX, BCL2, BCL2L1, BMP4, BRCA2, CAPN5, CCNE1, CHAT, COL9A3, CTNNA1, EREG, ESR1, FANCA, FANCF, FANCG, FGF7, FSHB, CENPI, FSHR, NR5A1, GDF9, ICAM1, IDH1, INHA, KDR, KIT, KITLG, PGR, PTGER4, PTPRN, SLIT3, SOD1, SRD5A1, STAT5B, TYRO3, UBB, UBE3A, NRIP1, FZD4, TP63, EIF2B2, EIF2B5, SLIT2, ADAMTS1 |
605 | GO:0051282 | 0.00 | 4.40 | 6.70 | 13 | 18 | regulation of sequestering of calcium ion | CCR5, DDIT3, XCR1, HTR2C, ITPR1, ITPR2, P2RX7, RYR1, RYR3, CCL21, TRPV1, TRPA1, CHERP |
606 | GO:0006919 | 0.00 | 4.39 | 13.44 | 26 | 36 | activation of cysteine-type endopeptidase activity involved in apoptotic process | APAF1, BAD, BID, BOK, CASP1, CASP9, CCK, CDKN2A, COL4A3, CTSH, F2R, F3, HIP1, SLC11A2, P2RX1, S100A8, S100A9, SNCA, CRADD, AIFM1, EIF2AK3, TNFSF15, CASP8AP2, PDCD6, BCL2L10, BCL2L11 |
607 | GO:0007229 | 0.00 | 4.38 | 22.81 | 44 | 61 | integrin-mediated signaling pathway | ADAM10, APOA1, DST, CD63, CDH17, COL3A1, COL16A1, CTGF, CTNNA1, EMP2, PTK2B, FCER1G, FGR, FUT8, HCK, ILK, ITGA1, ITGA3, ITGA4, ITGA5, ITGA9, ITGAD, ITGAM, ITGAV, ITGAX, ITGB1, ITGB4, LAMA5, PRKD1, PTK2, TYROBP, VAV1, MADCAM1, CUL3, ITGA8, ADAM15, ADAM9, ITGB1BP1, ADAMTS1, BCAR1, GAB2, VAV3, FERMT2, ADAMTS13 |
608 | GO:0048066 | 0.00 | 4.37 | 6.72 | 13 | 18 | developmental pigmentation | CD63, CITED1, PAX3, RAB27A, SOX10, TYR, TYRP1, ZIC2, AP1M1, AP3D1, USP13, ATP6AP2, RAB32 |
609 | GO:0001662 | 0.00 | 4.36 | 6.73 | 13 | 18 | behavioral fear response | BCL2, CCK, CRH, DBI, DPP4, EIF4E, EIF4G1, GABRA5, HTR2C, PENK, RPS6KB1, UCN, DEAF1 |
610 | GO:0006007 | 0.00 | 4.36 | 6.73 | 13 | 18 | glucose catabolic process | ALDOB, ALDOC, BAD, ENO2, ENO3, GAPDH, LDHA, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PPP2R5D |
611 | GO:0030857 | 0.00 | 4.36 | 6.73 | 13 | 18 | negative regulation of epithelial cell differentiation | ACVRL1, CCND1, S1PR3, HES1, IFNG, IL13, CITED1, SALL1, SRSF6, SOX9, STAT1, ZEB1, TP63 |
612 | GO:0040018 | 0.00 | 4.36 | 6.73 | 13 | 18 | positive regulation of multicellular organism growth | BBS2, BBS4, BCL2, CREB1, DIO3, GHRH, GHRHR, GHSR, IGF2, PPIB, STAT5B, VIL1, IKZF1 |
613 | GO:0044091 | 0.00 | 4.36 | 6.73 | 13 | 18 | membrane biogenesis | CAV2, CAV3, EMP2, FLOT2, PTEN, PTPRD, PEX19, S100A10, PEX11A, NRXN1, NRXN2, PEX16, IL1RAPL1 |
614 | GO:0048333 | 0.00 | 4.36 | 6.73 | 13 | 18 | mesodermal cell differentiation | BMP4, BMPR1A, EYA1, EYA2, ITGA3, ITGB1, ITGB4, SMAD1, TAL1, KDM6A, HMGA2, ITGA8, KLF4 |
615 | GO:0051898 | 0.00 | 4.36 | 6.73 | 13 | 18 | negative regulation of protein kinase B signaling | CRYBA1, DDIT3, DRD3, EPHA2, RAPGEF1, IGF1R, PTEN, PTPRJ, SFRP5, TSC2, KLF4, SLC9A3R1, PDCD6 |
616 | GO:0045815 | 0.00 | 4.35 | 16.08 | 31 | 43 | positive regulation of gene expression, epigenetic | ACTB, CHEK1, EP300, ERCC6, KAT2A, HMGA1, PHF2, SMARCD1, TBP, HIST1H4I, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, KAT2B, HIST1H3F, TAF1C, TAF1B, TAF1A, BAZ1B, DDX21 |
617 | GO:0051928 | 0.00 | 4.35 | 9.32 | 18 | 25 | positive regulation of calcium ion transport | ATP2B2, TSPO, CAMK2A, CRH, GCG, FFAR1, RYR2, S100A1, SLC9A1, STC1, SUMO1, UCN, WFS1, RGN, KCNE2, KCNE3, RAPGEF3, CREB3 |
618 | GO:0050766 | 0.00 | 4.32 | 9.35 | 18 | 25 | positive regulation of phagocytosis | AHSG, BCR, C3, CD36, CYBA, DNM2, F2RL1, FCER1G, GAS6, IL1B, ITGAV, RAB27A, RAP1GAP, SFTPD, SLC11A1, TUB, TULP1, ABCA7 |
619 | GO:0030574 | 0.00 | 4.29 | 14.59 | 28 | 39 | collagen catabolic process | ADAM10, COL1A1, COL3A1, COL4A3, COL4A5, COL4A6, COL5A2, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, COL11A1, COL12A1, COL15A1, COL16A1, COL17A1, CTSD, CTSK, FAP, ITGB1, PEPD, ADAM17, ADAM15, ADAM9, ADAMTS3, ADAMTS2 |
620 | GO:0071560 | 0.00 | 4.25 | 7.80 | 15 | 21 | cellular response to transforming growth factor beta stimulus | APAF1, ARG1, COL1A1, CX3CR1, DNMT1, FYN, PDE3A, PENK, XCL1, SOX9, STAR, CLEC3B, WNT2, STK16, RAPGEF3 |
621 | GO:0001505 | 0.01 | 4.24 | 5.20 | 10 | 14 | regulation of neurotransmitter levels | ACHE, ALDH2, ALDH9A1, DAGLA, COMT, GLUL, KCNJ10, PAH, PDE1B, SLC22A3 |
622 | GO:0051092 | 0.00 | 4.23 | 23.56 | 45 | 63 | positive regulation of NF-kappaB transcription factor activity | ALK, BTK, CAMK2A, CAT, CHUK, CLU, CTH, EDA, ICAM1, IL1B, INS, IRAK1, IRAK2, KRAS, LTF, NTRK1, PRKCI, PRKD1, PRKCQ, PRKCZ, EIF2AK2, PSMA6, RPS3, S100A8, S100A9, S100A12, TRAF1, TRAF2, UBB, TRIM25, IKBKG, TRADD, RIPK1, RIPK2, CFLAR, RPS6KA4, TNFSF18, ARHGEF2, CLOCK, TRIM13, TRIM22, TRIM38, RBCK1, MALT1, PRDX3 |
623 | GO:0031345 | 0.01 | 4.23 | 5.21 | 10 | 14 | negative regulation of cell projection organization | CAPZB, HRG, ITGA3, ITGB1, TACSTD2, PFN2, PRKCD, RAP1GAP, CCL21, NRXN1 |
624 | GO:1904064 | 0.00 | 4.22 | 13.06 | 25 | 35 | positive regulation of cation transmembrane transport | ABL1, ARF1, BAX, BMP4, CALM1, CALM3, EDNRA, F2, F2R, GSTM2, IL13, KCNJ11, NTSR1, RYR2, S100A1, XCL1, SLC9A1, SNCA, TRPC1, SUMO1, RGN, GSTO1, KCNE2, KCNE3, TRDN |
625 | GO:0007588 | 0.00 | 4.21 | 15.71 | 30 | 42 | excretion | AGTR1, AGTR2, AQP5, AQP6, AQP7, ATP6V1B1, AVP, AVPR2, CHRNB2, CHRNB4, CLCN5, CLCNKA, CLCNKB, COMT, DRD3, UTS2R, GUCA2B, KCNJ1, KNG1, PTGER4, SCNN1B, SCNN1G, SCTR, SLC12A1, STC1, TAC1, TRPV1, KCNK5, SLC9A3R1, CORIN |
626 | GO:0045761 | 0.00 | 4.21 | 13.09 | 25 | 35 | regulation of adenylate cyclase activity | ADRA2A, ADRB2, AVPR2, CALCR, CALM1, CALM3, DRD3, DRD5, EDNRA, FSHR, GALR1, GHRHR, GLP1R, GNAL, GNAS, NTRK1, NTRK2, P2RY11, PALM, RAF1, VIP, VIPR2, WFS1, GABBR2, CAP1 |
627 | GO:1904035 | 0.00 | 4.21 | 13.09 | 25 | 35 | regulation of epithelial cell apoptotic process | ABL1, ABL2, ANGPT1, BMP4, KRIT1, EIF2S1, FGA, FGG, GAS6, ICAM1, IGF1, IL13, KDR, SERPINE1, SERPINB13, PRKCI, SORT1, SFRP4, TNFAIP3, WFS1, SCG2, AKR1C3, SEMA5A, RAMP2, CAPN10 |
628 | GO:0031670 | 0.00 | 4.20 | 10.47 | 20 | 28 | cellular response to nutrient | ATP2B1, BGLAP, CCNE1, COL1A1, CYP24A1, GAS6, FOXA2, IL15, ITGB1, PAWR, CHMP1A, PENK, PIM1, PTN, SRF, USF1, FGF23, TRIM24, ADAMTS1, NR1H4 |
629 | GO:0030168 | 0.00 | 4.20 | 42.54 | 81 | 114 | platelet activation | A2M, ACTN1, ADRA2A, ALB, APOA1, APP, AXL, SERPING1, DAGLA, CALM1, CALM3, CALU, CD9, CD36, ENTPD2, CD63, CLU, COL1A1, COL3A1, DGKA, DGKB, DGKQ, F2, F2R, F2RL2, FCER1G, FYN, GNA15, GNAI1, GNAQ, GNB1, GP1BA, GP9, GRB2, HGF, HRG, IGF1, IGF2, ITPR1, ITPR2, KNG1, LAMP2, P2RX1, P2RY1, SERPINE1, PF4, PF4V1, PFN1, PRKCE, PRKCZ, PSAP, PTK2, PTPN1, RAC1, RAC2, RAF1, CX3CL1, SELP, SHC1, SOD1, SOS1, SPARC, SRF, TRPC3, TUBA4A, VAV1, VEGFB, VEGFC, YWHAZ, FZD6, DGKZ, DGKI, BCAR1, GNA14, ABCC4, RAPGEF3, VAV3, CAP1, PDPN, RAPGEF4, ADAMTS13 |
630 | GO:0048636 | 0.00 | 4.20 | 7.85 | 15 | 21 | positive regulation of muscle organ development | ADRB2, ARNTL, BCL2, BMP4, CCNB1, GATA4, GATA6, NRG1, HMGCR, RBPJ, PRKAA1, RPS6KB1, WNT2, USP2, AKAP6 |
631 | GO:1901863 | 0.00 | 4.20 | 7.85 | 15 | 21 | positive regulation of muscle tissue development | ADRB2, ARNTL, BCL2, BMP4, CCNB1, GATA4, GATA6, NRG1, HMGCR, RBPJ, PRKAA1, RPS6KB1, WNT2, USP2, AKAP6 |
632 | GO:0001958 | 0.01 | 4.19 | 5.24 | 10 | 14 | endochondral ossification | BMP4, BMP6, RUNX2, COL1A1, DLX5, FGFR3, GNAS, INPPL1, PEX7, PTHLH |
633 | GO:0007274 | 0.01 | 4.19 | 5.24 | 10 | 14 | neuromuscular synaptic transmission | CACNA1A, CHRM1, CHRNB2, CHRNB4, DTNA, EGR3, ETV5, NTF3, P2RX3, STXBP1 |
634 | GO:0031641 | 0.01 | 4.19 | 5.24 | 10 | 14 | regulation of myelination | HGF, NRG1, IFNG, PTEN, RARA, RARB, RXRA, EIF2AK3, FIG4, RNF10 |
635 | GO:0043001 | 0.01 | 4.19 | 5.24 | 10 | 14 | Golgi to plasma membrane protein transport | BBS1, BBS2, ACSL3, GOLGA4, KRT18, BLZF1, ARFRP1, VAMP5, RAB10, RAB31 |
636 | GO:0043372 | 0.01 | 4.19 | 5.24 | 10 | 14 | positive regulation of CD4-positive, alpha-beta T cell differentiation | ANXA1, CD80, CD86, HLX, IFNG, IL12B, PRKCZ, RARA, TNFSF4, RIPK2 |
637 | GO:0045653 | 0.01 | 4.19 | 5.24 | 10 | 14 | negative regulation of megakaryocyte differentiation | GABPA, PF4, HIST1H4I, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L |
638 | GO:0071353 | 0.01 | 4.19 | 5.24 | 10 | 14 | cellular response to interleukin-4 | ALAD, ARG1, HSP90AB1, IMPDH2, RPL3, XCL1, STAT6, KEAP1, IL24, CORO1A |
639 | GO:0071542 | 0.01 | 4.19 | 5.24 | 10 | 14 | dopaminergic neuron differentiation | PHOX2A, EN1, HIF1A, FOXA2, OTX2, RAC1, RYK, WNT1, WNT2, PHOX2B |
640 | GO:1902742 | 0.01 | 4.19 | 5.24 | 10 | 14 | apoptotic process involved in development | BAX, FGF4, B4GALT1, PPP2R1B, SIX3, SLIT3, PAX8, FZD5, SLIT2, BCL2L11 |
641 | GO:2000404 | 0.01 | 4.19 | 5.24 | 10 | 14 | regulation of T cell migration | ADAM10, ECM1, ITGA4, S100A7, CCL20, CCL21, XCL1, ADAM17, TNFSF14, CXCL13 |
642 | GO:0060193 | 0.00 | 4.17 | 22.07 | 42 | 59 | positive regulation of lipase activity | ABL2, ADCY3, ADCY5, ADCY6, ADCY9, AGTR1, ANG, APOA1, APOH, ARHGAP6, ARL1, AVPR1B, CALM1, CALM3, CAMK4, CREB1, LPAR1, EDNRA, ESR1, FGFR3, FLT1, GNA15, GNAQ, ITPR1, ITPR2, KIT, NTRK1, PDE1B, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCE, PRKCZ, PTAFR, SELE, NR1H2, S1PR4, GPR55 |
643 | GO:0071375 | 0.00 | 4.17 | 6.22 | 12 | 17 | cellular response to peptide hormone stimulus | ANXA5, CDC5L, CREB1, CRHBP, CYP11B1, FBN1, GNRHR, NR4A1, RANGAP1, SSTR2, WNT1, AKAP1 |
644 | GO:0048013 | 0.00 | 4.12 | 20.57 | 39 | 55 | ephrin receptor signaling pathway | ACTB, ACTG1, ADAM10, CDC42, CHN1, AP2S1, DNM1, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EPHA2, EPHA1, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, FYN, RBPJ, LIMK1, NTRK1, NTRK3, PTK2, RAC1, SDC2, SDCBP, ARHGEF7, KALRN, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, VAV3, ARPC1A |
645 | GO:0000183 | 0.00 | 4.11 | 11.59 | 22 | 31 | chromatin silencing at rDNA | PHF2, SUV39H1, TBP, UBTF, HIST1H4I, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HIST1H3F, TAF1C, TAF1B, TAF1A |
646 | GO:0002479 | 0.00 | 4.10 | 17.95 | 34 | 48 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | CD36, CYBA, CYBB, FCGR1A, FCGR1B, ITGAV, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, UBB, PSMF1, PSMD6, PSME3, PSMD14, SEC61B |
647 | GO:0008015 | 0.00 | 4.08 | 55.40 | 105 | 150 | blood circulation | ADCY6, ANGPT1, ATP1A3, ATP1A4, ATP1B3, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, BBS2, BCR, SERPING1, CACNA2D1, CACNB3, CACNB4, CALM1, CALM3, CASQ1, CASQ2, CAV3, CDC42, CHRM1, CHRM3, COL4A3, CXADR, CYB5R3, DSC2, RCAN1, DSP, HBEGF, E2F4, ELN, EPB41, FLI1, GAA, GATA4, GPX1, ARHGAP35, GSTM2, GUCY1B3, IFNG, ITGA1, ITPR1, ITPR2, KCND2, KCND3, KCNE1, KCNH2, KCNJ2, KCNJ8, KCNJ11, KCNJ12, KCNJ14, KCNK3, KNG1, SMAD7, MEOX2, OLR1, P2RY1, P2RY2, PDE3A, PDE4B, FXYD3, PRKCQ, PTPRJ, RYR1, RYR3, S100A1, SCN4B, SCN5A, SCN10A, SRSF1, SLC8A3, SLC9A1, SP4, SREBF1, STAT1, STC1, XCL2, TAZ, TNNC1, TNNI2, TNNT2, TRPC1, SUMO1, VEGFB, CSRP3, ITGB1BP1, SLIT2, GSTO1, ATG5, NUP155, HDAC4, KCNE2, HCN4, ABCC9, AKAP9, KCNMB2, IRX5, TRDN, CACNG2, SEMA3A, AHCYL1, BVES |
648 | GO:0051238 | 0.00 | 4.08 | 28.05 | 53 | 75 | sequestering of metal ion | ABL1, ATP1A2, ATP7B, BAX, CALM1, CALM3, CASQ1, CASQ2, CCR5, CYBA, DDIT3, DIAPH1, EDNRA, F2, F2R, PTK2B, XCR1, GSTM2, HRC, HTR2C, IL13, ITPR1, ITPR2, NTSR1, P2RX7, PDE4D, PLN, PRKCE, PRKD1, PTPN6, RYR1, RYR2, RYR3, S100A7, S100A8, S100A9, CCL21, XCL1, SNCA, HSP90B1, TRPC1, TRPV1, SLC30A2, SLC30A3, SLC30A4, AP3D1, TRPA1, GSTO1, AKAP6, ATG5, TRDN, CHERP, CORO1A |
649 | GO:1902743 | 0.00 | 4.08 | 8.98 | 17 | 24 | regulation of lamellipodium organization | CAPZB, DNM2, EPHA2, HRG, ENPP2, RAC1, RAC2, RREB1, FSCN1, CLRN1, VIL1, WNT1, ARHGEF7, SLIT2, HDAC4, ARPC2, WASF2 |
650 | GO:0043281 | 0.00 | 4.07 | 19.00 | 36 | 51 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | ALOX12, APAF1, BAD, BID, BOK, CASP1, CASP9, CCK, CDKN2A, COL4A3, CTGF, CTSH, EPHA7, F2R, F3, HIP1, MAP3K5, MGMT, SLC11A2, P2RX1, REST, RPS3, S100A8, S100A9, SOX2, TP63, CRADD, AIFM1, EIF2AK3, KIAA0141, TNFSF15, CASP8AP2, PDCD6, BCL2L10, BCL2L11, ARL6IP5 |
651 | GO:0044057 | 0.00 | 4.06 | 86.23 | 162 | 232 | regulation of system process | ABAT, ADCY6, ADM, ADRA1B, ADRA2A, ALOX12, ANXA6, APOA1, ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B3, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, AVPR1B, BDKRB2, BMP6, BMPR2, CACNA1B, CACNA2D1, CACNB3, CACNB4, CALM1, CALM3, CASQ1, CASQ2, CAV3, CD38, CDK9, CHRM1, CHRM3, CNN1, CPS1, CRH, CRHBP, CRP, CRY1, CTGF, CXADR, DAPK3, DBH, ACE, DSC2, DSP, HBEGF, EDN3, CTTN, FGA, FGG, FLT1, GAA, GALR1, GATA4, GDF9, GHSR, GLP1R, GLS, GSTM2, GTF2I, HIF1A, HMGCR, HRH1, HRC, HRH2, ICAM1, IGF1, IGFBP5, IL1B, INHA, INS, ITPR1, ITPR2, KCNA1, KCND2, KCND3, KCNE1, KCNH2, KCNJ2, KCNJ11, KCNJ12, KCNJ14, KCNK3, KCNQ1, KISS1, SMAD7, PPP1R12B, OXTR, P2RX1, P2RX4, P2RY1, P2RY2, PDE4B, PDE4D, FXYD3, PLN, PRKCQ, PTGS1, PTPRM, RGS2, RPS6KB1, RYR1, RYR2, RYR3, S100A1, SCN4B, SCN5A, SCN10A, CX3CL1, SGK1, SHC1, SLC8A3, SLC22A5, SLN, SOD1, SP4, SREBF1, SRF, SSTR2, TACR3, TMF1, TNNC2, TNNC1, TNNI2, TNNI3, TNNT1, TNNT2, TRPC1, TRPC3, SUMO1, UCN, NR1H2, TRPV1, CSRP3, AKAP1, PDE5A, KAT2B, PHOX2B, CTDP1, KLF4, SLC9A3R1, KCNK6, GSTO1, AKAP6, NUP155, HDAC4, KCNE2, HCN4, ABCC9, AKAP9, CALCRL, KCNMB2, IRX5, TRDN, CACNG2, SEMA3A, AHCYL1, BVES, AKAP13 |
652 | GO:1903169 | 0.01 | 4.06 | 6.33 | 12 | 17 | regulation of calcium ion transmembrane transport | BMP4, CACNB3, CACNB4, CAV3, PDE4B, S100A1, SLC9A1, SUMO1, RGN, KCNE2, KCNE3, RAPGEF3 |
653 | GO:0060337 | 0.01 | 4.04 | 6.35 | 12 | 17 | type I interferon signaling pathway | BST2, IFIT1, IFIT3, IRF1, IRF2, IRF5, ISG20, OAS2, OAS3, SP100, IFITM3, IFITM2 |
654 | GO:0002286 | 0.01 | 4.04 | 6.35 | 12 | 17 | T cell activation involved in immune response | F2RL1, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, PSEN1, RAB27A, SLC11A1, STX11 |
655 | GO:0014911 | 0.01 | 4.03 | 6.36 | 12 | 17 | positive regulation of smooth muscle cell migration | BCL2, LPAR1, F3, IGF1, P2RY2, P2RY6, PTGER4, RPS6KB1, VTN, NRP1, HDAC4, RAPGEF3 |
656 | GO:0030947 | 0.01 | 4.03 | 6.36 | 12 | 17 | regulation of vascular endothelial growth factor receptor signaling pathway | ARNT, FLT1, HHEX, HIF1A, IL1B, ITGA5, PTPN1, VEGFB, VEGFC, VTN, FZD4, PDCD6 |
657 | GO:0055021 | 0.01 | 4.03 | 6.36 | 12 | 17 | regulation of cardiac muscle tissue growth | CAV3, CCNB1, CXADR, GATA4, GATA6, NRG1, RBPJ, KCNK2, TP73, WNT2, CTDP1, AKAP6 |
658 | GO:0071378 | 0.01 | 4.03 | 6.36 | 12 | 17 | cellular response to growth hormone stimulus | CISH, CSH1, GH2, PTK2, PTPN1, PTPN6, STAR, STAT1, STAT3, STAT5B, ADAM17, SOCS3 |
659 | GO:1900026 | 0.01 | 4.03 | 6.36 | 12 | 17 | positive regulation of substrate adhesion-dependent cell spreading | APOA1, CDC42, DNM2, FGA, FGG, RAC1, RAC3, RREB1, S100A10, ARHGEF7, ARPC2, OLFM4 |
660 | GO:0055117 | 0.00 | 4.01 | 10.07 | 19 | 27 | regulation of cardiac muscle contraction | ADRA1B, CALM1, CALM3, CASQ2, CAV3, CTGF, GSTM2, HRC, KCNQ1, SMAD7, P2RX4, RGS2, SCN10A, SLC9A1, UCN, PDE5A, GSTO1, HDAC4, HCN4 |
661 | GO:0019731 | 0.00 | 3.99 | 10.10 | 19 | 27 | antibacterial humoral response | ADM, ANG, APP, KLK3, DMBT1, FAU, FGA, LTF, PGC, RPL39, SEMG1, SLPI, TAC1, VIP, HIST1H2BG, HIST2H2BE, HIST1H2BJ, SPON2, SPINK5 |
662 | GO:0071230 | 0.00 | 3.99 | 10.10 | 19 | 27 | cellular response to amino acid stimulus | ASS1, BCL2L1, COL1A1, COL3A1, COL5A2, COL6A1, COL16A1, CYBA, DNMT1, DNMT3B, GLRA1, GLRA2, HMGCS2, HNRNPD, IPO5, NTRK2, ZEB1, RAPGEF3, RRAGA |
663 | GO:0042127 | 0.00 | 3.98 | 37.95 | 73 | 107 | regulation of cell proliferation | ABL2, JAG1, AGTR1, ANGPT1, BIRC2, XIAP, FXYD2, BID, BLK, BRCA1, BTK, CHEK1, CLC, CREB1, DBH, DHCR7, DNMT1, E2F4, EMX1, FANCA, FGR, NR5A2, FYN, GPX1, CXCL3, GRPR, GUCY2C, HHEX, HMGN1, INHA, JUND, LAMA5, LMO1, TACSTD2, TNFRSF11B, SERPINE1, PF4, PF4V1, PGR, SERPINB5, PTGER2, PTGS1, RPA3, SALL1, CXCL6, SGK1, SOS1, SOS2, SRMS, STAT6, TAL1, TNFRSF1A, TNFRSF1B, XRCC5, TNK1, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, CFLAR, TNFSF18, ARHGEF2, NUAK1, SGK2, TNK2, PRG4, CREB3, DEAF1, CXCL13, TXNIP, RBBP9, JTB |
664 | GO:0001894 | 0.00 | 3.96 | 7.42 | 14 | 20 | tissue homeostasis | BARD1, COL9A1, CTGF, CTSH, FGF7, GNAS, ITGB1, KCNJ1, KDR, P2RX4, PTHLH, SFTPD, STK11, CUBN |
665 | GO:0042098 | 0.00 | 3.96 | 7.43 | 14 | 20 | T cell proliferation | ABL1, BAX, CCND3, CD151, CTPS1, FYN, ITGAD, P2RX7, SATB1, SLC11A1, TNFRSF4, TNFSF14, MALT1, BTN3A1 |
666 | GO:0006289 | 0.04 | 3.94 | 3.72 | 7 | 10 | nucleotide-excision repair | BRCA2, FANCC, ATXN3, RAD51D, RAD52, DCLRE1A, SLC30A9 |
667 | GO:0031018 | 0.00 | 3.93 | 7.47 | 14 | 20 | endocrine pancreas development | ANXA1, CLU, NR5A2, FOXA2, HNF4G, ONECUT1, HES1, IAPP, INS, PAX4, PDE3B, SOX9, EIF2AK3, ONECUT2 |
668 | GO:0050731 | 0.00 | 3.92 | 35.90 | 67 | 96 | positive regulation of peptidyl-tyrosine phosphorylation | ABL1, ADRA2A, ANGPT1, CCK, CD3E, CD4, CD80, CD36, CD44, CD81, CNTF, CSF1R, CSPG4, CTF1, ACE, EFNA1, EFNA5, EREG, ERCC6, PTK2B, FGF7, FGFR3, FLT3, FYN, GAS6, HCLS1, HGF, NRG1, HPX, HES1, ICAM1, IFNA2, IFNG, IGF1, IGF2, IL12B, IL13, IL15, IL18, INS, ISL1, ITGA5, ITGB1, KIT, KITLG, NTF3, ENPP2, RELN, PTGER4, PTPN1, STK11, ADAM17, TNFRSF1A, VEGFB, VEGFC, VTN, RIPK2, TNFRSF18, NRP1, TNFSF18, UNC119, ARHGEF2, CRLF1, ABI1, TNK2, SEMA4D, IL24 |
669 | GO:0060428 | 0.04 | 3.92 | 3.73 | 7 | 10 | lung epithelium development | BMP4, CDC42, FGF7, FGFR3, SRSF6, WNT2, ADAMTSL2 |
670 | GO:0008542 | 0.00 | 3.92 | 11.22 | 21 | 30 | visual learning | ABL2, ADRA1B, APP, ATP1A2, ATP1A3, CHRNB2, CREB1, CTNS, DBH, DRD3, GRIN2A, HIF1A, HMGCR, HRH1, HRH2, ITGB1, KIT, KRAS, PDE1B, SGK1, DEAF1 |
671 | GO:0032652 | 0.00 | 3.92 | 7.47 | 14 | 20 | regulation of interleukin-1 production | ANXA1, APOA1, CASP5, S1PR3, F2R, GAS6, GHSR, HSPB1, IFI16, IFNG, IL10, SMAD3, TNFAIP3, TRIM16 |
672 | GO:1990090 | 0.00 | 3.92 | 7.47 | 14 | 20 | cellular response to nerve growth factor stimulus | APP, CDC5L, CREB1, CSNK1D, DNMT1, EEF2, KAT2A, NTRK2, RPS3, TAC1, TRPV1, EIF4A3, RAB35, STMN2 |
673 | GO:0046579 | 0.04 | 3.92 | 3.74 | 7 | 10 | positive regulation of Ras protein signal transduction | NRG1, IGF1, KRAS, KITLG, NTRK1, SHOC2, DGKI |
674 | GO:0007620 | 0.04 | 3.92 | 3.74 | 7 | 10 | copulation | ABAT, P2RX1, PI3, SEMG1, TAC1, DDO, EDDM3A |
675 | GO:0051966 | 0.04 | 3.92 | 3.74 | 7 | 10 | regulation of synaptic transmission, glutamatergic | ATP1A2, CNR1, GRIK3, PSEN1, SYT1, UCN, DGKI |
676 | GO:0001964 | 0.04 | 3.92 | 3.74 | 7 | 10 | startle response | GLRA1, GRIN2A, NRG1, KCNA1, PARK2, PENK, UCN |
677 | GO:0050690 | 0.00 | 3.92 | 7.48 | 14 | 20 | regulation of defense response to virus by virus | ARF1, CD4, CD8B, CD28, AP1S1, AP2S1, FYN, HCK, EIF2AK2, RAC1, AP1S2, AP1M1, ELMO1, AP1M2 |
678 | GO:0045730 | 0.04 | 3.92 | 3.74 | 7 | 10 | respiratory burst | CD52, CYBA, CYBB, HCK, PGAM1, PRKCQ, SLC11A1 |
679 | GO:0050802 | 0.04 | 3.92 | 3.74 | 7 | 10 | circadian sleep/wake cycle, sleep | CHRNB2, CRH, DRD3, KCNA2, SRD5A1, STAR, PER3 |
680 | GO:0030318 | 0.04 | 3.92 | 3.74 | 7 | 10 | melanocyte differentiation | EDN3, KIT, CITED1, RAB27A, SOX10, TYRP1, USP13 |
681 | GO:0006297 | 0.04 | 3.91 | 3.74 | 7 | 10 | nucleotide-excision repair, DNA gap filling | PCNA, RFC3, RFC4, RFC5, RPA2, RPA3, UBB |
682 | GO:0006544 | 0.04 | 3.91 | 3.74 | 7 | 10 | glycine metabolic process | AGXT, AMT, DHFR, GLDC, SHMT1, SHMT2, GLYAT |
683 | GO:0006760 | 0.04 | 3.91 | 3.74 | 7 | 10 | folic acid-containing compound metabolic process | DHFR, SARDH, SHMT1, SHMT2, TYMS, GGH, ALDH1L1 |
684 | GO:0006828 | 0.04 | 3.91 | 3.74 | 7 | 10 | manganese ion transport | SLC11A2, SLC11A1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2 |
685 | GO:0006995 | 0.04 | 3.91 | 3.74 | 7 | 10 | cellular response to nitrogen starvation | RHAG, RHCE, RHD, BECN1, ATG5, ATG13, ATG7 |
686 | GO:0009299 | 0.04 | 3.91 | 3.74 | 7 | 10 | mRNA transcription | ARNT, ATF4, DDIT3, DDX5, EREG, HIF1A, SRF |
687 | GO:0009437 | 0.04 | 3.91 | 3.74 | 7 | 10 | carnitine metabolic process | ACADL, ACADM, ALDH9A1, CRAT, SHMT1, SLC22A5, BBOX1 |
688 | GO:0014067 | 0.04 | 3.91 | 3.74 | 7 | 10 | negative regulation of phosphatidylinositol 3-kinase signaling | CRYBA1, PTEN, TSC2, TWIST1, KLF4, SLC9A3R1, STAMBP |
689 | GO:0030826 | 0.04 | 3.91 | 3.74 | 7 | 10 | regulation of cGMP biosynthetic process | PTK2B, GUCA1A, GUCA1B, GUCA2A, GUCA2B, RCVRN, GUCA1C |
690 | GO:0032332 | 0.04 | 3.91 | 3.74 | 7 | 10 | positive regulation of chondrocyte differentiation | ACVRL1, BMP6, RUNX2, HOXD11, IHH, SMAD3, SOX9 |
691 | GO:0032780 | 0.04 | 3.91 | 3.74 | 7 | 10 | negative regulation of ATPase activity | CNN3, LTF, PLN, TNNI3, TNNT2, RGN, ABCA7 |
692 | GO:0032878 | 0.04 | 3.91 | 3.74 | 7 | 10 | regulation of establishment or maintenance of cell polarity | KRIT1, PTK2B, FLOT2, IGF1, LLGL2, RNF41, ARFGEF1 |
693 | GO:0032897 | 0.04 | 3.91 | 3.74 | 7 | 10 | negative regulation of viral transcription | JUN, REST, SP100, TRIM21, HMGA2, TRIM13, IFITM3 |
694 | GO:0035067 | 0.04 | 3.91 | 3.74 | 7 | 10 | negative regulation of histone acetylation | BRCA1, SET, SNCA, TAF7, TWIST1, ATG5, ATG7 |
695 | GO:0043011 | 0.04 | 3.91 | 3.74 | 7 | 10 | myeloid dendritic cell differentiation | CAMK4, CD86, RBPJ, PSEN1, RELB, TNFSF9, DHRS2 |
696 | GO:0043302 | 0.04 | 3.91 | 3.74 | 7 | 10 | positive regulation of leukocyte degranulation | F2RL1, FCER1G, FGR, IL13, PTAFR, VAMP8, GAB2 |
697 | GO:0043501 | 0.04 | 3.91 | 3.74 | 7 | 10 | skeletal muscle adaptation | GTF2I, IGFBP5, IL15, RPS6KB1, TNNC1, TNNT1, CFLAR |
698 | GO:0043650 | 0.04 | 3.91 | 3.74 | 7 | 10 | dicarboxylic acid biosynthetic process | GLS, GLUD1, GOT1, GOT2, SLC1A3, ALDH4A1, KYNU |
699 | GO:0044788 | 0.04 | 3.91 | 3.74 | 7 | 10 | modulation by host of viral process | APCS, CAV2, STOM, LTF, PARK2, PPIB, VAPB |
700 | GO:0044849 | 0.04 | 3.91 | 3.74 | 7 | 10 | estrous cycle | ADRB2, ANXA1, CLU, ETS1, OXTR, PTN, TRPM2 |
701 | GO:0045725 | 0.04 | 3.91 | 3.74 | 7 | 10 | positive regulation of glycogen biosynthetic process | AKT2, IGF1, IGF2, INS, DYRK2, EPM2AIP1, SORBS1 |
702 | GO:0045793 | 0.04 | 3.91 | 3.74 | 7 | 10 | positive regulation of cell size | CDK4, HIF1A, HSP90AB1, TP73, OGT, RB1CC1, RAPGEF3 |
703 | GO:0046827 | 0.04 | 3.91 | 3.74 | 7 | 10 | positive regulation of protein export from nucleus | CAMK4, GAS6, SFN, IL1B, PPM1A, CAMK1, RAPGEF3 |
704 | GO:0048643 | 0.04 | 3.91 | 3.74 | 7 | 10 | positive regulation of skeletal muscle tissue development | ADRB2, ARNTL, BCL2, HMGCR, PRKAA1, RPS6KB1, USP2 |
705 | GO:0061298 | 0.04 | 3.91 | 3.74 | 7 | 10 | retina vasculature development in camera-type eye | ACVR2B, ACVRL1, BMPR2, HIF1A, FZD4, NRP1, SLC4A7 |
706 | GO:0070570 | 0.04 | 3.91 | 3.74 | 7 | 10 | regulation of neuron projection regeneration | HGF, NTRK3, OMG, PRRX1, PTEN, TNR, KLF4 |
707 | GO:0071318 | 0.04 | 3.91 | 3.74 | 7 | 10 | cellular response to ATP | P2RX4, P2RY11, RYR3, SOD1, HSP90B1, TRPV1, CIB2 |
708 | GO:0072673 | 0.04 | 3.91 | 3.74 | 7 | 10 | lamellipodium morphogenesis | ENPP2, RREB1, VIL1, ARHGEF7, WASF1, ABI1, WASF2 |
709 | GO:2001026 | 0.04 | 3.91 | 3.74 | 7 | 10 | regulation of endothelial cell chemotaxis | FGF4, HRG, HSPB1, KDR, PRKD1, SEMA5A, CXCL13 |
710 | GO:0051592 | 0.00 | 3.91 | 19.80 | 37 | 53 | response to calcium ion | ANXA5, ANXA7, ANXA11, BAD, CCND1, ENTPD6, CRHBP, DPEP1, DUSP1, PTK2B, FGA, FGG, GDI1, GPLD1, GUCA1A, HNRNPD, JUN, JUND, LIPC, P2RX7, PENK, RYR3, SCN5A, SPARC, TNNT2, TRPC1, TRPC3, TSHB, SLC25A12, AKR1C3, ADAM9, CPNE1, PDCD6, RASA4, SLC25A13, TXNIP, AHCYL1 |
711 | GO:0010035 | 0.00 | 3.90 | 10.56 | 20 | 29 | response to inorganic substance | BMP4, CD9, CD36, ATF2, DHFR, EEF1A2, ERCC6, FANCC, HMGCS1, IL1B, IL1R1, NTRK1, PRDX1, RXRA, SIPA1, SOD2, SCGB1A1, SLC14A2, RGN, FBLN5 |
712 | GO:0009617 | 0.00 | 3.88 | 60.21 | 112 | 162 | response to bacterium | ABCA1, ABL1, ADH5, ALAD, ARG1, ASS1, ATP4B, AXL, BCR, PRDM1, BMP6, BYSL, TSPO, CASP1, CASP9, CD6, CD80, CD86, TNFRSF8, ENTPD2, CHIT1, CHUK, CCR5, CNP, CNR1, CNR2, COMT, CPS1, CX3CR1, DCN, DNMT1, EDNRA, F2R, F3, GFI1, GPX1, CXCL1, CXCL3, HCK, HIF1A, HMGCS2, ICAM1, IGF1, IL1B, IL10RA, IL12RB2, IL13, IL18, IDO1, IRAK1, IRAK2, IRF5, JUN, JUND, KCNJ8, CD180, CITED1, TNFRSF11B, P2RY2, PAWR, PDE4B, PDE4D, PENK, PF4, PF4V1, SERPINB9, PRKCE, MAPK8, EIF2AK2, PTAFR, PTGER1, PTGER2, PTGER4, RARA, UPF1, RPS6KB1, CXCL5, SELE, SNCA, SPARC, STAR, STAT1, STAT5B, ABCC8, TNFAIP3, TNFRSF1B, TNFSF4, TNFRSF4, SCGB1A1, VCAM1, VIL1, FZD5, OGT, PPM1D, PARG, ADAM9, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, SOCS3, LITAF, CTR9, NR1H4, IL18BP, TRIB1, BAIAP2, GJB6, MALT1, PRDX3, IL24 |
713 | GO:0003015 | 0.00 | 3.88 | 54.98 | 102 | 147 | heart process | ADM, ADRA1B, ADRB2, AGTR2, ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B3, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, CACNA1B, CACNA2D1, CACNB3, CACNB4, CALM1, CALM3, CASQ1, CASQ2, CAV3, CDC42, CTGF, CXADR, ACE, DSC2, DSP, HBEGF, EDN3, GAA, GATA4, GJA5, GLP1R, GPX1, GSTM2, HRC, IFNG, ITPR1, ITPR2, KCND2, KCND3, KCNE1, KCNH2, KCNJ2, KCNJ11, KCNJ12, KCNJ14, KCNK3, KCNQ1, SMAD7, P2RX4, PDE4B, PDE4D, FXYD3, PLN, RGS2, RYR1, RYR2, RYR3, S100A1, SCN4B, SCN5A, SCN10A, SRSF1, SLC8A3, SLC9A1, SOD1, SP4, SREBF1, STC1, TAC1, TACR3, TAZ, TNNC1, TNNI2, TNNI3, TNNT2, TRPC1, SUMO1, UCN, VEGFB, CSRP3, PDE5A, KCNK6, GSTO1, ATG5, NUP155, HDAC4, KCNE2, HCN4, ABCC9, AKAP9, IRX5, RAMP3, TRDN, CACNG2, SEMA3A, CORIN, AHCYL1, BVES |
714 | GO:0007179 | 0.00 | 3.87 | 17.15 | 32 | 46 | transforming growth factor beta receptor signaling pathway | ACVR1, ACVRL1, AMHR2, BMPR1A, CBL, CCNC, CCNT1, CCNT2, CDK8, CDK9, COL3A1, CREB1, E2F4, FSHB, FUT8, GDF9, HPGD, JUN, LTBP2, SMAD1, SMAD9, SERPINE1, PRKCZ, PTK2, RBL1, SP1, KLF10, USP9X, USP9Y, ADAM9, GDF15, FERMT2 |
715 | GO:0014812 | 0.00 | 3.87 | 12.34 | 23 | 33 | muscle cell migration | AAMP, ANXA1, BCL2, ACE, LPAR1, F3, IGF1, IGFBP3, IGFBP5, ILK, P2RY2, P2RY6, SERPINE1, PTGER4, RPS6KB1, SIX1, VTN, NRP1, ITGB1BP1, SLIT2, HDAC4, TRIB1, RAPGEF3 |
716 | GO:0045787 | 0.00 | 3.85 | 9.61 | 18 | 26 | positive regulation of cell cycle | ASCL1, CCNC, CCND3, CCNH, CCNT1, CCNT2, OVOL1, PGGT1B, PIM1, RARA, STIL, SRPK2, TRIM21, ADAM17, FOSL1, CCPG1, BCL2L11, CITED2 |
717 | GO:0016259 | 0.00 | 3.85 | 22.07 | 41 | 59 | selenocysteine metabolic process | FAU, RPL10A, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, RPL14, RPL23, EIF4A3, RPL35 |
718 | GO:0071356 | 0.00 | 3.85 | 14.45 | 27 | 39 | cellular response to tumor necrosis factor | ASS1, BRCA1, ENTPD2, CD58, COL1A1, CRHBP, CYBA, KAT2A, GPD1, ICAM1, KCNJ11, NTRK2, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, XCL2, VCAM1, TRPV1, ARHGEF2, HDAC4, IL18BP, KLF2, ADAMTS7 |
719 | GO:0014896 | 0.00 | 3.84 | 8.59 | 16 | 23 | muscle hypertrophy | AGTR2, CDK9, CYBA, GATA4, GATA6, IGF1, RYR2, SLC9A1, TRPC3, CSRP3, SORBS2, PDE5A, AKAP6, KDM4A, HDAC4, AKAP13 |
720 | GO:0031103 | 0.00 | 3.84 | 8.60 | 16 | 23 | axon regeneration | APOA1, BCL2, TSPO, CALU, CTNNA1, DHFR, ISL1, JUN, NTRK3, OMG, PTEN, RXRA, TNR, KLF4, NREP, CHST3 |
721 | GO:0032922 | 0.00 | 3.84 | 8.60 | 16 | 23 | circadian regulation of gene expression | ARNTL, ATF4, CRY1, CRY2, CSNK1D, DRD3, PER1, RELB, TOP1, NRIP1, OGT, HDAC3, PER3, USP2, CLOCK, RAI1 |
722 | GO:1901532 | 0.00 | 3.84 | 8.60 | 16 | 23 | regulation of hematopoietic progenitor cell differentiation | GABPA, HES1, KDR, PF4, EIF2AK2, SOS1, SOS2, ZNF16, HIST1H4I, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L |
723 | GO:1903201 | 0.00 | 3.84 | 8.60 | 16 | 23 | regulation of oxidative stress-induced cell death | ATF4, GPX1, HGF, HIF1A, HSPB1, INS, PARK2, PSAP, PYCR1, SFPQ, SOD1, SOD2, TRPM2, BAG5, HDAC6, TRAP1 |
724 | GO:0035637 | 0.00 | 3.83 | 43.76 | 81 | 117 | multicellular organismal signaling | ATP1A1, ATP1A2, ATP1A3, ATP1A4, ATP1B3, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, AVP, CACNA1A, CACNA2D1, CACNB3, CACNB4, CALM1, CALM3, CASQ1, CASQ2, CHRNB4, CXADR, DPP6, DRD5, DSC2, DSP, S1PR1, GJA5, GLRA1, HRC, IFNG, ITPR1, ITPR2, KCNA1, KCNA2, KCND2, KCND3, KCNE1, KCNH2, KCNJ2, KCNJ11, KCNJ12, KCNJ14, KCNK3, KCNQ1, NRCAM, P2RX1, P2RX3, P2RX4, PAWR, PDE4D, FXYD3, PLN, RYR1, RYR2, RYR3, SCN1A, SCN2A, SCN3A, SCN4B, SCN5A, SCN7A, SCN8A, SCN10A, SLC8A3, SLC9A1, SOD1, TNNI3, TNR, TRPC1, CNTNAP1, KCNK6, NUP155, KCNE2, HCN4, ABCC9, AKAP9, KCNMB2, TRDN, CACNG2, CORIN, AHCYL1 |
725 | GO:0034767 | 0.02 | 3.81 | 4.83 | 9 | 13 | positive regulation of ion transmembrane transport | CFTR, CRH, GCG, P2RX7, RELN, PTAFR, SLC34A1, STC1, UCN |
726 | GO:0035265 | 0.02 | 3.80 | 4.84 | 9 | 13 | organ growth | ACVR2B, ADRA1B, AGTR2, BCL2, S1PR1, FGF7, SMAD1, PRKAR1A, SORBS2 |
727 | GO:0033238 | 0.02 | 3.80 | 4.84 | 9 | 13 | regulation of cellular amine metabolic process | ABAT, CHRNB2, ACSL3, HPRT1, PARK2, PDE1B, PRKCD, SNCA, TACR3 |
728 | GO:0006333 | 0.02 | 3.80 | 4.84 | 9 | 13 | chromatin assembly or disassembly | CHD3, SMARCA4, SMARCC2, SMARCD1, SMARCD3, SMARCE1, TAL1, BAZ1B, SUPT16H |
729 | GO:0006874 | 0.00 | 3.79 | 65.74 | 121 | 176 | cellular calcium ion homeostasis | ABL1, ABL2, ADCY5, ADM, ADRA1B, AGTR1, ANXA6, ANXA7, ATP1A2, ATP2B1, ATP2B2, ATP2B3, ATP7B, AVP, AVPR1B, BDKRB2, BMP4, CACNA1A, CACNB4, CALCR, CALM1, CALM3, CASQ1, CASQ2, CAV3, CD4, CD36, CD38, CD52, CCR3, CCR5, CCR8, CYBA, DDIT3, DIAPH1, DRD3, DRD5, S1PR1, LPAR1, S1PR3, EDN3, EDNRA, ESR1, F2, F2R, F2RL1, PTK2B, GALR1, GLP1R, GNA15, GNAT2, GNB1, GNG3, CCR10, XCR1, UTS2R, GRM1, GSTM2, GTF2I, HEXB, HRC, HTR2C, IL1B, IL13, ITGB1, ITPR2, KCNK3, KISS1, KNG1, NTSR1, OXTR, P2RX3, P2RX4, P2RX5, P2RX7, P2RY1, P2RY2, P2RY4, PDE4D, PIK3CB, PLN, PRKCE, PRKD1, PTPN6, PYGM, RYR1, RYR2, RYR3, CCL21, XCL1, SLC8A3, SNCA, STC1, TAC1, TNNI3, TPT1, HSP90B1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, TRPV1, CSRP3, S1PR4, INPP4B, TRPA1, RGN, SLC24A1, VAPB, GSTO1, AKAP6, ATG5, TRDN, CIB2, CHERP, CXCL13, SCGN, CCR9, IMMT, CORO1A |
730 | GO:0019933 | 0.00 | 3.79 | 9.71 | 18 | 26 | cAMP-mediated signaling | ADCY3, ADCY5, ADCY6, ADCY9, ADM, DGKQ, EPHA5, GHRH, GHRHR, GLP1R, PDE3A, PDE4D, PDE7A, SOX9, AKAP6, RIMS2, RAPGEF3, RAPGEF4 |
731 | GO:0021762 | 0.00 | 3.78 | 9.72 | 18 | 26 | substantia nigra development | ACTB, ATP5F1, CALM1, CALM3, CASP5, CDC42, CNP, COX6B1, FGFR3, GLUD1, LDHA, RAD1, S100A1, ZNF148, DYNLL1, INA, SYNGR3, YWHAQ |
732 | GO:0032760 | 0.00 | 3.78 | 9.72 | 18 | 26 | positive regulation of tumor necrosis factor production | TNFRSF8, CD36, CLU, CYBA, FCER1G, HSPB1, IFNG, IL12B, ISL1, PF4, PTAFR, SPN, TWIST1, RIPK1, RIPK2, ARHGEF2, SPON2, ARFGEF2 |
733 | GO:0045840 | 0.00 | 3.78 | 9.72 | 18 | 26 | positive regulation of mitotic nuclear division | BIRC5, CD28, DRD3, EDN3, EREG, IGF1, IGF1R, IGF2, IL1A, IL1B, INS, PTEN, RB1, AURKA, CUL3, BECN1, DLGAP5, UBE2C |
734 | GO:0051496 | 0.00 | 3.78 | 9.72 | 18 | 26 | positive regulation of stress fiber assembly | APOA1, CTGF, LPAR1, EPHA1, LIMK1, SMAD3, PFN2, PRKCQ, RAC1, S100A10, SDC4, TAC1, WNT11, ARHGEF5, ITGB1BP1, BAG4, SORBS3, RAPGEF3 |
735 | GO:0003309 | 0.02 | 3.77 | 4.86 | 9 | 13 | type B pancreatic cell differentiation | ARNTL, BAD, BMP4, BMP6, CDK6, GATA6, RFX3, RHEB, CLOCK |
736 | GO:0006884 | 0.02 | 3.77 | 4.86 | 9 | 13 | cell volume homeostasis | ADD1, ANXA7, CLCN3, CLCN6, CLNS1A, E2F4, KCNN4, P2RX7, SLC6A12 |
737 | GO:0010894 | 0.02 | 3.77 | 4.86 | 9 | 13 | negative regulation of steroid biosynthetic process | ATP1A1, GFI1, INSIG1, REST, SNAI1, SOD1, NR1H4, ERLIN1, ERLIN2 |
738 | GO:0019835 | 0.02 | 3.77 | 4.86 | 9 | 13 | cytolysis | ALB, BAD, C7, GPLD1, GZMH, HPRT1, P2RX7, PF4, RRAGA |
739 | GO:0021854 | 0.02 | 3.77 | 4.86 | 9 | 13 | hypothalamus development | NR0B1, BAX, CRH, ETS1, SOX3, SRD5A1, UBB, NRP1, SEMA3A |
740 | GO:0030511 | 0.02 | 3.77 | 4.86 | 9 | 13 | positive regulation of transforming growth factor beta receptor signaling pathway | DAB2, ING2, CITED1, SDCBP, STK11, ADAM17, ITGA8, CITED2, GIPC1 |
741 | GO:0031954 | 0.02 | 3.77 | 4.86 | 9 | 13 | positive regulation of protein autophosphorylation | CALM1, CALM3, ACE, INS, RAP2A, RAP2B, VEGFC, TOM1L1, RAD50 |
742 | GO:0032201 | 0.02 | 3.77 | 4.86 | 9 | 13 | telomere maintenance via semi-conservative replication | FEN1, PCNA, PRIM2, UPF1, RFC3, RFC4, RFC5, RPA2, RPA3 |
743 | GO:0035774 | 0.02 | 3.77 | 4.86 | 9 | 13 | positive regulation of insulin secretion involved in cellular response to glucose stimulus | BAD, CFTR, CRH, GCG, GPLD1, GPR27, HIF1A, OXCT1, C2CD2L |
744 | GO:0035855 | 0.02 | 3.77 | 4.86 | 9 | 13 | megakaryocyte development | EP300, FLI1, KIT, PIP4K2A, PTPN6, SRF, TAL1, ABI1, WASF2 |
745 | GO:0042346 | 0.02 | 3.77 | 4.86 | 9 | 13 | positive regulation of NF-kappaB import into nucleus | EDA, IL1B, IL12B, IL18, PRKCQ, TRIP6, TNFSF14, RBCK1, EDAR |
746 | GO:0098868 | 0.02 | 3.77 | 4.86 | 9 | 13 | bone growth | COL9A1, COMP, EVC, FGFR3, RARA, RARB, STC1, CER1, CARM1 |
747 | GO:0044724 | 0.00 | 3.77 | 21.64 | 40 | 58 | single-organism carbohydrate catabolic process | ALDOB, ALDOC, ARNT, BAD, ENO2, ENO3, FUT6, FUT8, GALE, GALK1, GAPDH, GK2, GLB1, GM2A, GPD1, GPD2, HEXB, HIF1A, IGF1, KHK, LDHA, OGDH, P2RX7, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PPP2R5D, PRKAA1, PRKAG1, RPE, SORD, STAT3, OGT, HDAC4, XYLB, AKR1A1, FUT9, TREH |
748 | GO:0033993 | 0.00 | 3.75 | 109.68 | 202 | 300 | response to lipid | ABCA2, ABCA3, ABL2, ACADS, ACVR1, ADCY3, ADCY5, ADRB2, AGTR2, AGXT, NR0B1, ALDH3A1, ALDOB, ALOX12, ANXA1, ANXA3, APOA1, APOH, AREG, ARNTL, STS, ASCL1, ATP1A1, ATP1A2, ATP1A3, ATP2B1, AVP, BAX, BCHE, CCND1, BCL2, BGLAP, BID, BMP4, BRCA1, BRCA2, KLF9, C3, CA2, CALCR, CALM1, CALM3, CCNE1, CD4, CD38, CDK2, CDK4, CDKN1A, CDO1, COL1A1, CRH, CRHBP, CRY1, CRY2, CTNNA1, CTSH, CTSV, CYP24A1, DAB2, BRINP1, DDX5, DTYMK, DUSP1, LPAR1, PHC1, EEF2, ELK1, EP300, ESR1, ESRRG, ETS1, F7, PTK2B, FGA, FLT3, NR5A2, NR5A1, GATA6, NR6A1, GHRHR, GNAI1, GOT1, GPLD1, GRN, H2AFZ, HMBS, HMGCS1, NR4A1, HNF4G, HNMT, HNRNPD, PRMT2, IDH1, IGF2, IGFBP2, IHH, IL1RN, IL15, IL17A, ISL1, ITGB1, KCNJ11, KRAS, KRT13, KRT19, LCAT, LDHA, SMAD6, SCGB2A1, CNOT2, NTRK3, NTSR1, OGG1, OXTR, PAM, PCNA, SERPINF1, PER1, PFKFB1, PGR, SERPINB9, PIM1, PLN, PPP5C, PSPH, PTEN, PTN, PTPRN, RAN, RARB, RB1, REST, RNF6, RXRG, S100B, SGK1, SHC1, SLC9A3, SLIT3, SMARCA4, SOX2, SOX9, SP100, SRD5A1, SSTR2, STAT3, STC1, AURKA, TACR3, TAF7, TAT, NR2F1, NR2F2, NR2C1, NR2C2, TYR, UBE2L3, UBE3A, UCN, NR1H2, WNT2, WNT11, ZNF35, TRIM25, PRDM2, RAB7A, FOSL1, FGF23, NRIP1, SLC10A3, FZD4, FZD7, URI1, TRIM24, BUD31, MBD4, RQCD1, AIFM1, KLF4, SLIT2, CLOCK, RNF14, ABCG1, NR1I3, NR1D2, NR2E3, HDAC6, PDCD7, RAMP2, RAMP3, CITED2, PGRMC2, RBM14, CARM1, SLC34A2, TRIM16, TXNIP, RUVBL2, GPR83, SOX30, FZD10, AKAP13 |
749 | GO:0045445 | 0.00 | 3.74 | 10.83 | 20 | 29 | myoblast differentiation | JAG1, BMP4, CSRP2, DDIT3, DTYMK, FLOT2, NRG1, HMGCR, IFRD1, IGF1, RBPJ, IL18, ISL1, RB1, REST, SOX9, SRF, KCNAB1, CXCL14, MAML1 |
750 | GO:0006955 | 0.00 | 3.74 | 37.71 | 71 | 106 | immune response | ARHGDIB, AZGP1, BMP6, BMPR1A, BPI, TNFRSF8, TNFSF8, CD70, ADGRE5, CHIT1, CCR5, CCR8, ACKR2, LTB4R, CNR2, CYP11B1, EDA, ETS1, FCGR3B, GAS6, CCR10, CXCL1, CXCL3, GZMH, HRH2, IGF1R, IK, IL1R1, IL17A, ITGAD, SMAD6, TNFRSF11B, ENPP2, ENPP3, PF4, PF4V1, PRG2, RFX1, CXCL6, CXCL5, ZEB1, TNFRSF1A, TNFRSF1B, TNFRSF4, VIPR1, PXDN, IL1R2, IKBKAP, S1PR4, TNFSF14, TNFSF10, TNFSF9, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, IL18RAP, IL32, CXCL14, GTPBP1, TNFSF15, COL4A3BP, CHST4, PRG4, PRG3, SEMA4D, PROCR, CCR9, IFI44L, IL24 |
751 | GO:0006953 | 0.00 | 3.74 | 10.85 | 20 | 29 | acute-phase response | AHSG, APCS, ASS1, CNR1, CRP, F2, FGA, HIF1A, HP, IL1A, IL1B, IL1RN, INS, ITIH4, ORM2, SAA4, STAT3, STAT5B, TRPV1, CD163 |
752 | GO:0006977 | 0.00 | 3.73 | 16.83 | 31 | 45 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | ATM, CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, UBB, CRADD, PSMF1, PSMD6, PSME3, PSMD14 |
753 | GO:1902400 | 0.00 | 3.73 | 16.83 | 31 | 45 | intracellular signal transduction involved in G1 DNA damage checkpoint | ATM, CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, UBB, CRADD, PSMF1, PSMD6, PSME3, PSMD14 |
754 | GO:0031638 | 0.00 | 3.72 | 23.94 | 44 | 64 | zymogen activation | APAF1, APOH, BAD, BAX, BID, BOK, CASP1, CASP9, CCK, CDKN2A, COL4A3, CTSH, DHCR24, F2R, F3, FGA, FGG, HIP1, IFI16, KLKB1, SMAD3, SLC11A2, P2RX1, SERPINE1, PAWR, S100A8, S100A9, SNCA, CLEC3B, TRAF2, TRADD, RIPK1, CRADD, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR, AIFM1, EIF2AK3, TNFSF15, CASP8AP2, PDCD6, BCL2L10, BCL2L11 |
755 | GO:0044259 | 0.00 | 3.72 | 23.94 | 44 | 64 | multicellular organismal macromolecule metabolic process | ADAM10, ARG1, BMP4, SERPINH1, COL1A1, COL3A1, COL4A3, COL4A5, COL4A6, COL5A2, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, COL11A1, COL12A1, COL15A1, COL16A1, COL17A1, CTGF, CTSD, CTSK, ACE, F2, F2R, FAP, HIF1A, IHH, ITGB1, CIITA, P2RX7, PEPD, ADAM17, UCN, AKR1C3, SERPINB7, ADAM15, ADAM9, ADAMTS3, ADAMTS2, TRAM2, RAPGEF3 |
756 | GO:0044774 | 0.00 | 3.72 | 23.94 | 44 | 64 | mitotic DNA integrity checkpoint | ATM, CCND1, CDK2, CDKN1A, ATF2, FOXO4, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, RPA2, SETMAR, TOP2A, TOP2B, TP73, UBB, XPC, HMGA2, DGKZ, TP63, CRADD, PSMF1, PSMD6, PSME3, PSMD14, CHEK2 |
757 | GO:0030278 | 0.00 | 3.71 | 11.94 | 22 | 32 | regulation of ossification | JAG1, ATP6AP1, RUNX2, DDX5, DLX5, EGR2, GNAS, HGF, IGF1, ILK, JUND, SMAD1, PBX1, PRKD1, PTGER4, PTK2, SOX11, TAC1, TP63, DHRS3, PDLIM7, TOB2 |
758 | GO:0044092 | 0.00 | 3.71 | 10.19 | 19 | 28 | negative regulation of molecular function | ATP1A2, CALM1, CALM3, CASQ2, CRHBP, GRK6, GSTM2, KCNE1, KCNQ1, PRKCE, KCNAB1, RAB9A, SLC9A3R1, GSTO1, OXSR1, KCNE2, KCNE3, TRDN, CREB3 |
759 | GO:0042476 | 0.01 | 3.71 | 5.97 | 11 | 16 | odontogenesis | AQP5, AQP6, BGLAP, COL1A1, EDNRA, PAM, PAX9, TUFT1, TWIST1, ZNF22, ADAMTS1 |
760 | GO:0045937 | 0.00 | 3.70 | 21.88 | 41 | 61 | positive regulation of phosphate metabolic process | ABCA1, ADM, AGTR2, AVPR2, CALCR, DRD5, ACSL3, FZD2, GHRH, GHRHR, GLP1R, GNAL, GNAS, GPLD1, GUCA1A, GUCA1B, GUCA2A, GUCA2B, HRH1, IGBP1, INSL3, SMAD3, PPP1R12A, NTSR1, P2RY11, PAWR, PF4, PTAFR, PTHLH, RCVRN, STAT3, VIP, VIPR2, WFS1, RGN, AKAP6, AKAP12, GUCA1C, CALCRL, RAMP2, CAP1 |
761 | GO:2001244 | 0.00 | 3.70 | 11.97 | 22 | 32 | positive regulation of intrinsic apoptotic signaling pathway | BAD, BAX, BCL2, BCL2L1, BID, CLU, DDIT3, DFNA5, PARK2, RPS3, S100A8, S100A9, SFPQ, SIAH1, SOD1, TP73, UBB, SLC9A3R1, EIF2AK3, BCLAF1, BCL2L11, SERINC3 |
762 | GO:0002891 | 0.01 | 3.69 | 5.98 | 11 | 16 | positive regulation of immunoglobulin mediated immune response | C3, CD28, FCER1G, FCER2, HPX, IFNG, XCL1, STAT6, TNFSF4, UNG, WHSC1 |
763 | GO:0042104 | 0.01 | 3.69 | 5.98 | 11 | 16 | positive regulation of activated T cell proliferation | CD86, IGF1, IGF2, IGFBP2, IL2RA, IL12B, IL18, STAT5B, TNFSF4, TNFSF9, HHLA2 |
764 | GO:0048665 | 0.01 | 3.69 | 5.98 | 11 | 16 | neuron fate specification | ASCL1, ATOH1, EVX1, EYA1, FOXA2, HOXC10, HOXD10, ISL1, NTRK3, SIX1, SOX1 |
765 | GO:0060008 | 0.01 | 3.69 | 5.98 | 11 | 16 | Sertoli cell differentiation | NR0B1, ATRX, CTSV, ESR1, GATA4, ICAM1, NTRK1, RAB13, RARA, SOX9, AKAP9 |
766 | GO:0006283 | 0.00 | 3.67 | 13.09 | 24 | 35 | transcription-coupled nucleotide-excision repair | CCNH, EP300, ERCC1, ERCC3, ERCC4, ERCC5, ERCC6, HMGN1, PCNA, RFC3, RFC4, RFC5, RPA2, RPA3, UBB, XPA, CUL4A, COPS3, COPS2, RBX1, PPIE, COPS8, COPS6, COPS5 |
767 | GO:0007585 | 0.00 | 3.67 | 13.09 | 24 | 35 | respiratory gaseous exchange | ADH5, ADRB2, PHOX2A, ATP1A2, CFTR, COX5B, COX15, CSF2RB, EDNRA, ELN, FUT8, GAA, GLRA1, GLS, HNMT, NTSR1, SFTPB, SFTPD, SLC5A3, TNNC1, KDM6A, PHOX2B, TMPRSS11D, TRAF4 |
768 | GO:0009891 | 0.03 | 3.64 | 4.26 | 8 | 12 | positive regulation of biosynthetic process | CTGF, F2, FCER2, KDR, NR2F1, SERPINB7, HDAC6, CNPY2 |
769 | GO:0009261 | 0.01 | 3.64 | 7.11 | 13 | 19 | ribonucleotide catabolic process | HPRT1, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, PDE5A, RAPGEF3, PDE10A |
770 | GO:0045824 | 0.01 | 3.64 | 7.11 | 13 | 19 | negative regulation of innate immune response | A2M, ADAR, SERPING1, IFI16, IGF2, INS, SERPINB9, RPS19, SERPINB4, TNFAIP3, TYRO3, NR1H2, TRAFD1 |
771 | GO:0071715 | 0.01 | 3.64 | 7.11 | 13 | 19 | icosanoid transport | AGTR2, ANXA1, BDKRB2, ACE, DRD3, ACSL4, IL1B, NTSR1, P2RX4, P2RX7, P2RY2, SLCO2A1, ABCC4 |
772 | GO:1903959 | 0.01 | 3.64 | 7.11 | 13 | 19 | regulation of anion transmembrane transport | AKT2, CFTR, CLCN3, CLCN5, CLCN6, CLCN7, CLCNKA, CLCNKB, GRK6, PTAFR, SLC34A1, VDAC2, RIPK1 |
773 | GO:0060048 | 0.00 | 3.63 | 8.19 | 15 | 22 | cardiac muscle contraction | ATP1A3, GAA, KCNE1, KCNH2, SCN4B, SRSF1, TAZ, TNNC1, TNNI2, TNNI3, TNNT2, VEGFB, CSRP3, NUP155, KCNE2 |
774 | GO:0051289 | 0.00 | 3.63 | 15.33 | 28 | 41 | protein homotetramerization | ACACB, ACADL, ACADS, CAT, CDA, CRYZ, CTH, DECR1, GLS, GOLGA2, GPX3, HSD17B10, HPRT1, IDE, IMPDH2, KCNJ2, KCNJ12, PEX14, PEX5, RXRA, RXRG, RYR3, SHMT1, SHMT2, SOD2, TP63, TRPA1, USP16 |
775 | GO:0051291 | 0.00 | 3.63 | 16.41 | 30 | 44 | protein heterooligomerization | ACVRL1, BIRC2, BIRC3, CHRNB2, CHRNB4, COL1A1, COL6A1, COL6A2, CLDN3, CTNNA1, GLRA1, HBA2, HBE1, IDE, ILK, KCNC2, P2RX1, PPP5C, PRKAA1, PRKCZ, SEMG1, STXBP3, TNNT2, TRAF2, TSC1, OGT, TRADD, RIPK1, CLDN1, SEPT9 |
776 | GO:0034113 | 0.00 | 3.60 | 8.22 | 15 | 22 | heterotypic cell-cell adhesion | APOA1, CD58, CXADR, DSC2, DSP, IL1RN, ITGA4, ITGA5, ITGAD, ITGAV, ITGAX, ITGB1, NRCAM, MADCAM1, KLF4 |
777 | GO:0002478 | 0.00 | 3.60 | 18.64 | 34 | 50 | antigen processing and presentation of exogenous peptide antigen | CD36, CYBA, CYBB, FCGR1A, FCGR1B, ITGAV, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, UBB, PSMF1, PSMD6, PSME3, PSMD14, SEC61B |
778 | GO:0014855 | 0.00 | 3.60 | 8.23 | 15 | 22 | striated muscle cell proliferation | ANGPT1, CCNB1, CXADR, GATA4, GATA6, NRG1, RBPJ, KCNK2, SMAD1, PRKAR1A, SIX1, STAT3, TP73, WNT2, CFLAR |
779 | GO:0033628 | 0.00 | 3.60 | 8.23 | 15 | 22 | regulation of cell adhesion mediated by integrin | DPP4, EFNA1, EPHA2, EPHA8, HRG, SERPINE1, PDE3B, PTK2, PTPN6, RAC3, CCL21, ADAM9, ITGB1BP1, PIEZO1, CXCL13 |
780 | GO:0045070 | 0.00 | 3.60 | 8.23 | 15 | 22 | positive regulation of viral genome replication | ADAR, ADARB1, CD28, STOM, NR5A2, IFIT1, PPIB, PPID, SRPK2, STAU1, TOP2A, VAPB, PPIE, PPIH, TRIM38 |
781 | GO:1903523 | 0.00 | 3.60 | 8.23 | 15 | 22 | negative regulation of blood circulation | ADM, AGTR2, ATP1A1, ATP1A2, BMPR2, CRP, F2R, HIF1A, HMGCR, INS, PDE4D, PLN, CX3CL1, TAC1, PDE5A |
782 | GO:0034763 | 0.00 | 3.60 | 17.58 | 32 | 47 | negative regulation of transmembrane transport | ADRA2A, AKT2, ATP1A2, CALM1, CALM3, CASQ2, CAV3, DRD3, GRK6, GSTM2, KCNE1, KCNH2, KCNQ1, NTSR1, OAZ1, OAZ2, PAWR, PLN, PRKCE, SEMG1, SLN, SPINK1, TWIST1, SUMO1, KCNAB1, SLC9A3R1, GSTO1, OXSR1, KCNE2, KCNE3, TRDN, YWHAQ |
783 | GO:0072413 | 0.00 | 3.60 | 17.58 | 32 | 47 | signal transduction involved in mitotic cell cycle checkpoint | ATM, CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, UBB, CRADD, PSMF1, PSMD6, PSME3, PSMD14, CHEK2 |
784 | GO:1902402 | 0.00 | 3.60 | 17.58 | 32 | 47 | signal transduction involved in mitotic DNA damage checkpoint | ATM, CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, UBB, CRADD, PSMF1, PSMD6, PSME3, PSMD14, CHEK2 |
785 | GO:0031571 | 0.00 | 3.57 | 19.82 | 36 | 53 | mitotic G1 DNA damage checkpoint | ATM, CCND1, CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, RPA2, TP73, UBB, DGKZ, TP63, CRADD, PSMF1, PSMD6, PSME3, PSMD14 |
786 | GO:0032776 | 0.00 | 3.57 | 9.35 | 17 | 25 | DNA methylation on cytosine | DNMT1, DNMT3B, HIST1H4I, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HIST1H3F |
787 | GO:1901362 | 0.00 | 3.57 | 14.86 | 28 | 43 | organic cyclic compound biosynthetic process | ALAD, ALAS1, ALAS2, ASIP, CDH3, COX15, CPOX, CPS1, CTNS, DBH, HMBS, IDO1, SLC11A2, OAT, PAH, PYCR1, ALDH18A1, QDPR, TRPC1, TYR, TYRP1, UROS, PDXK, ALDH4A1, SUCLA2, RAPGEF2, ABCB6, PRG3 |
788 | GO:0006968 | 0.00 | 3.55 | 10.47 | 19 | 28 | cellular defense response | CCR3, CCR5, CX3CR1, PTK2B, ITGB1, KLRC2, KLRC3, SPN, TNFRSF4, TYROBP, ZNF148, VEZF1, FOSL1, KLRC4, BECN1, PAGE1, CCR9, CD300C, CD160 |
789 | GO:0043550 | 0.00 | 3.55 | 10.47 | 19 | 28 | regulation of lipid kinase activity | CD81, CDC42, EEF1A2, EPHA8, PTK2B, FGFR3, FGR, FLT1, FLT3, KIT, PTK2, RAC1, RB1, RBL1, RBL2, CCL21, PIK3R3, KLF4, VAV3 |
790 | GO:0009615 | 0.00 | 3.54 | 15.94 | 29 | 43 | response to virus | BAD, BCL2L1, BCL3, CDK6, CHUK, CLU, DDX1, FGR, GTF2F1, HMGA1, HSPB1, IFNGR1, PENK, PSMA2, ABCE1, CCL22, XCL1, TPT1, TNFSF4, FOSL1, HMGA2, IKBKG, URI1, BANF1, DDX21, BCL2L11, IFI44, IVNS1ABP, PIM2 |
791 | GO:0031100 | 0.00 | 3.54 | 11.58 | 21 | 31 | organ regeneration | ADM, ANGPT2, ANXA3, APOA1, APOH, CCND1, CCNE1, CDK2, CDK4, CDKN1A, EIF4A1, F7, FLT3, GAS6, HGF, HMBS, PFKFB1, SHC1, TYMS, WNT1, SOCS3 |
792 | GO:0022617 | 0.00 | 3.53 | 25.43 | 46 | 68 | extracellular matrix disassembly | A2M, ADAM10, BMP1, BSG, CAPN1, CD44, CDH1, COL1A1, COL3A1, COL4A3, COL4A5, COL4A6, COL5A2, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, COL11A1, COL12A1, COL15A1, COL16A1, COL17A1, CTRB1, CTSD, CTSK, CTSV, DCN, DPP4, ELN, ETS1, FAP, FBN1, FGFR4, KLKB1, LAMA3, LAMA5, PSEN1, FSCN1, ADAM17, TPSAB1, ADAM15, ADAM9, ADAMTS4, ADAMTS5 |
793 | GO:0010332 | 0.00 | 3.53 | 11.59 | 21 | 31 | response to gamma radiation | ATM, ATR, BAX, BCL2, BCL2L1, BRCA2, CYBA, ELK1, ERCC6, FANCD2, GPX1, IL1B, PRKAA1, RAD51, TP73, XRCC2, XRCC5, TP63, SOCS3, TRIM13, CHEK2 |
794 | GO:0035690 | 0.00 | 3.53 | 11.59 | 21 | 31 | cellular response to drug | CRHBP, DPEP1, GAS6, GPLD1, HIF1A, IL1B, KCNC1, KCNH2, KCNQ1, PDE4A, PDE4B, QDPR, RAP2A, REST, HMGA2, EIF2B5, EFTUD2, KCNE2, RAPGEF3, CERS1, CHEK2 |
795 | GO:0002690 | 0.00 | 3.52 | 12.70 | 23 | 34 | positive regulation of leukocyte chemotaxis | EDN3, EDNRA, F2RL1, F7, PTK2B, GAS6, CXCL1, CXCL3, IL1B, SERPINE1, PF4, PF4V1, RAC1, RAC2, CCL21, CXCL6, CXCL5, CX3CL1, VEGFB, VEGFC, TNFSF18, CXCL14, CREB3 |
796 | GO:0050679 | 0.00 | 3.52 | 14.90 | 27 | 40 | positive regulation of epithelial cell proliferation | BAD, CCND1, BMPR1A, CDC42, CDH3, DLX5, DLX6, ERBB2, ESR1, EYA1, FGF7, B4GALT1, GLUL, GRN, IGF1, IHH, PTN, RREB1, SCN5A, SRSF6, SOX9, SOX11, TNFAIP3, TWIST1, VEGFC, FZD7, TP63 |
797 | GO:0009952 | 0.00 | 3.52 | 14.91 | 27 | 40 | anterior/posterior pattern specification | ACVR2A, ACVR2B, BMPR2, CRKL, EMX2, EN1, GATA4, GRSF1, HOXC10, HOXC11, HOXD3, HOXD9, HOXD10, HOXD11, HES1, OTX1, PBX1, PCSK5, SIX3, NR2F2, TULP3, WNT1, WNT2, WNT2B, YY1, ALDH1A2, ATP6AP2 |
798 | GO:0042509 | 0.00 | 3.51 | 13.84 | 25 | 37 | regulation of tyrosine phosphorylation of STAT protein | CNTF, CSF1R, CTF1, FGFR3, FLT3, FYN, HCLS1, HPX, HES1, IFNA2, IFNG, IGF1, IL12B, IL13, IL15, IL18, ISL1, KIT, PPP2R1A, PTGER4, TNFRSF1A, TNFRSF18, TNFSF18, CRLF1, IL24 |
799 | GO:0071383 | 0.00 | 3.51 | 20.43 | 37 | 55 | cellular response to steroid hormone stimulus | ACVR1, AGTR2, ANXA1, ARG1, ASS1, ATP1A1, ATP1A2, ATP1A3, ATP2B1, KLF9, CASP9, CRH, CRHBP, DNMT3B, ELK1, FLT3, H2AFZ, HMBS, HMGCS2, HNRNPD, IL10, IL17A, PAWR, SERPINF1, SERPINB9, REST, SRD5A1, SSTR2, STAR, STC1, UBE2L3, AKR1C3, URI1, TRIM24, AIFM1, RAMP3, RUVBL2 |
800 | GO:0043549 | 0.02 | 3.50 | 5.46 | 10 | 15 | regulation of kinase activity | BAD, FOXA2, PARK2, PFKFB1, PFKFB2, PRPSAP1, RANBP2, ZNF16, RAD50, PRDX3 |
801 | GO:0036498 | 0.00 | 3.50 | 14.96 | 27 | 40 | IRE1-mediated unfolded protein response | ACADVL, ADD1, ASNA1, BAX, TPP1, ERN1, EXTL3, HDGF, DNAJB9, PTPN1, SHC1, SSR1, SULT1A3, WFS1, ZBTB17, ATP6V0D1, GOSR2, TATDN2, CUL7, BCL2L11, PREB, PDIA6, SEC61B, PDIA5, COPS5, KDELR3, SEC63 |
802 | GO:0019438 | 0.00 | 3.49 | 12.86 | 24 | 37 | aromatic compound biosynthetic process | ALAD, ALAS1, ALAS2, ASIP, TSPO, CDH3, COX15, CPOX, CTNS, DBH, HMBS, IDO1, SLC11A2, PAH, QDPR, TRPC1, TYR, TYRP1, UROS, PDXK, SUCLA2, RAPGEF2, ABCB6, PRG3 |
803 | GO:0010942 | 0.03 | 3.48 | 4.38 | 8 | 12 | positive regulation of cell death | CRH, HBA2, HP, IL17A, KCNK2, TRIM13, KATNB1, RRAGA |
804 | GO:0072401 | 0.00 | 3.48 | 18.33 | 33 | 49 | signal transduction involved in DNA integrity checkpoint | ATM, CDC5L, CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, UBB, CRADD, PSMF1, PSMD6, PSME3, PSMD14, CHEK2 |
805 | GO:0043410 | 0.00 | 3.47 | 27.61 | 50 | 75 | positive regulation of MAPK cascade | ADRA1B, ADRA2A, ADRB2, ALK, CAV2, CD81, CSPG4, LPAR1, EDN3, EFNA1, EPHA8, FLT3, FPR1, GNG3, HGF, IGF1, IGF1R, IGF2, IGFBP3, ILK, INS, IRAK1, IRAK2, ITGA1, ITGB1, KISS1, NTF3, NTRK2, NTRK3, TNFRSF11B, P2RX7, PDE6G, PDE6H, PIK3CB, PRKAA1, PRKCE, PSAP, RYK, S100A12, SOD1, SOX2, TNFRSF1B, TP73, TNFRSF4, IKBKG, MAPKAPK5, PDE5A, TNFRSF6B, S1PR2, SORBS3 |
806 | GO:2001056 | 0.00 | 3.46 | 23.94 | 43 | 64 | positive regulation of cysteine-type endopeptidase activity | ALOX12, APAF1, BAD, BAX, BID, BOK, CASP1, CASP9, CCK, CDKN2A, COL4A3, CTGF, CTSH, F2R, F3, HIP1, IFI16, SMAD3, MAP3K5, SLC11A2, P2RX1, PAWR, REST, RPS3, S100A8, S100A9, SNCA, TRAF2, TRADD, RIPK1, CRADD, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR, AIFM1, EIF2AK3, TNFSF15, CASP8AP2, PDCD6, BCL2L10, BCL2L11, ARL6IP5 |
807 | GO:0045137 | 0.00 | 3.45 | 45.25 | 81 | 121 | development of primary sexual characteristics | ACVR2A, NR0B1, AMHR2, ANG, ATRX, BAX, CCND1, BCL2, BCL2L1, BMP4, BOK, BRCA2, CAPN5, CCNE1, CHAT, COL9A3, CTNNA1, CTSV, ERCC1, EREG, ESR1, FANCA, FANCF, FANCG, FGF7, FSHB, CENPI, FSHR, NR5A1, GATA4, GATA6, GDF9, HSD17B10, HMGCS1, ICAM1, IDH1, ING2, INHA, INSL3, KDR, KIT, KITLG, NTRK1, PGR, PRKACG, PTGER4, PTPRN, RAB13, RARA, RRM1, SALL1, SLIT3, SOD1, SOX9, SRD5A1, SRY, STAR, STAT5B, TMF1, TSPY1, UBB, UBE3A, WNT2B, CSDE1, NRIP1, FZD4, AKR1C3, ADAM15, EIF2B2, EIF2B5, EIF2S2, SLIT2, ADAMTS1, REC8, BCL2L11, AKAP9, IRX5, FSTL3, CITED2, SEMA3A, PRDX4 |
808 | GO:0008283 | 0.00 | 3.42 | 81.52 | 149 | 233 | cell proliferation | ACHE, ADRA1B, ALK, AMBN, ANXA7, RERE, BCAT1, TNFRSF17, BOK, ZFP36L2, BST2, BUB1B, BYSL, DAGLA, CCND3, CD5, TNFSF8, CD70, CD151, CDK11B, CDC25A, CDC25C, CDC27, CDK3, CDK9, CENPF, CHRM3, CKS1B, CKS2, CLK1, CR2, CSE1L, CSPG4, CTPS1, DAB2, DKC1, DMBT1, DTYMK, E4F1, ELN, EML1, EMP1, EMX2, EPHB1, EPS8, EPS15, ERCC1, ERG, ETV6, F2RL1, GPC4, GCG, KAT2A, NR6A1, GNAT1, GNB1, HDGF, HLCS, HPRT1, IFI16, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IL15RA, IMPDH1, IMPDH2, INSIG1, INSL4, IRF2, ISG20, ITGAD, KCNA1, CD180, MAP3K11, CITED1, P2RX7, PA2G4, PRDX1, PCM1, PCNA, PIM1, PPP1R8, PRKCD, PYY, RAC1, RAG2, REG1B, RPS27, RRM1, RYK, SATB1, SETMAR, STIL, SIPA1, SLC11A1, FSCN1, STAT4, TACC1, TSPY1, TYMS, TYR, UBE2L3, UBE2V2, WNT2B, PICALM, FZD6, FZD9, GFI1B, BLZF1, CDC14A, PDXK, NUMB, TNFSF14, CDC16, EIF2S2, USP13, USP8, ARHGEF1, AURKB, NUMBL, COPS2, LIPG, BCAR1, DLGAP5, GINS1, ZEB2, SETDB1, COL4A3BP, TSPAN1, TRAIP, APC2, CITED2, RAPGEF3, ARIH2, TACC3, TACC2, PDPN, KHDRBS1, YME1L1, ZMYND11, RAB10, MALT1, ASCC3, KIF2C, BTN3A1, CD160 |
809 | GO:0009636 | 0.00 | 3.41 | 32.43 | 58 | 87 | response to toxic substance | ALAD, ARG1, ASS1, BAX, BCL2, CASP9, CCNB1, CDH1, CDK2, CDK4, CDKN1A, CHUK, CNP, CPOX, CPS1, CYP2F1, DNMT1, DNMT3B, ERCC6, ETS1, GRIA4, GUCY2C, HIF1A, HMBS, HSPA9, HSP90AA1, IL1B, KCNC1, KCNC2, MGMT, CIITA, PARK2, PENK, PPP2CB, EIF2AK2, RAD51, RPS6KB1, SCN3A, SCN8A, SHC1, SLC1A3, SLC9A1, SRD5A1, SRF, STAR, TYMS, UROS, XPA, SLC30A4, OGT, AIFM1, SLC22A8, HDAC6, DHRS2, GLYAT, CERS1, RAB10, ADAMTS13 |
810 | GO:0050768 | 0.00 | 3.40 | 11.13 | 20 | 30 | negative regulation of neurogenesis | ASCL2, BMP4, BMPR1A, TSPO, COL3A1, CTNNA1, DRD3, F2, FGFR3, NRG1, NTRK3, PCM1, PTN, SOX11, STAT3, DYNLT1, ARHGEF2, RNF10, NRG3, VAX1 |
811 | GO:0033209 | 0.00 | 3.40 | 30.23 | 54 | 81 | tumor necrosis factor-mediated signaling pathway | TNFRSF17, TNFRSF8, CD70, EDA, PTK2B, KRT18, TNFRSF11B, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, RELB, SKP1, STAT1, ADAM17, TNFRSF1B, TNFSF4, TNFRSF4, NSMAF, CUL1, TNFSF14, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, TNFSF18, UBA3, PSMF1, BAG4, PSMD6, TNFSF15, PSME3, PSMD14, TNFSF13B, EDAR |
812 | GO:0071222 | 0.00 | 3.38 | 21.28 | 38 | 57 | cellular response to lipopolysaccharide | ABCA1, ABL1, ARG1, ASS1, AXL, BYSL, TSPO, CD80, CD86, CD36, ENTPD2, CEBPE, CCR5, CX3CR1, GFI1, HIF1A, HMGCS2, ICAM1, IFNG, IL10, IL12B, P2RY2, SERPINE1, PDE4B, PDE4D, MAPK8, RARA, UPF1, CCL20, STAR, TNFRSF1B, TNFSF4, OGT, ADAM9, LITAF, CTR9, SPON2, IL24 |
813 | GO:0006614 | 0.00 | 3.38 | 26.93 | 48 | 72 | SRP-dependent cotranslational protein targeting to membrane | FAU, RPL10A, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, SRP9, SRP14, SRP19, SRP68, SSR1, RPL14, RPL23, SEC61B, RPL35, SEC63 |
814 | GO:0009913 | 0.00 | 3.38 | 10.06 | 18 | 27 | epidermal cell differentiation | ATOH1, ATP2B2, BMP4, ERCC3, GFI1, HES1, RAC1, SFRP4, SOD1, USH2A, CLRN1, PTCH2, KLF4, SLC9A3R1, SLC4A7, KEAP1, SEC24B, SPINK5 |
815 | GO:0002474 | 0.00 | 3.38 | 23.56 | 42 | 63 | antigen processing and presentation of peptide antigen via MHC class I | AZGP1, CANX, CD36, CYBA, CYBB, ACE, FCER1G, FCGR1A, FCGR1B, ITGAV, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, UBB, PSMF1, PSMD6, PSME3, PSMD14, SEC24B, IFI30, SEC23A, SEC24A, SEC61B |
816 | GO:0018108 | 0.00 | 3.37 | 27.37 | 49 | 74 | peptidyl-tyrosine phosphorylation | ALK, APLP2, APP, AXL, BCR, CLK1, CLK3, DYRK1A, EPHA2, EPHA1, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, ERBB2, F2R, EFEMP1, FGFR4, FLT1, FLT4, HRG, IL12RB2, INSRR, MAP3K11, NTRK1, NTRK2, NTRK3, PPP2R1A, PRKCD, PRKCE, PRKCZ, EIF2AK2, PSEN1, PTPN6, RAP2B, RYK, SHC1, SPINK1, TTK, TYRO3, WEE1, DYRK2, STK16, DYRK4, BAZ1B, DYRK1B, ABI2 |
817 | GO:0046887 | 0.02 | 3.37 | 5.59 | 10 | 15 | positive regulation of hormone secretion | BMP6, CREB1, EDN3, GALR1, INHA, P2RY1, SOX11, TAC1, TMF1, VAMP8 |
818 | GO:0046364 | 0.00 | 3.37 | 21.32 | 38 | 57 | monosaccharide biosynthetic process | ALDOB, ALDOC, ATF4, CRY1, ENO2, ENO3, G6PC, GAPDH, GCG, KAT2A, GOT1, GOT2, GPD1, GPD2, INS, MDH1, MDH2, PCK1, PCK2, PFKFB1, PGAM1, PGAM2, PGK1, PGM1, PRKACB, PRKACG, RANBP2, SLC25A1, SORD, OGT, SLC25A12, KAT2B, RGN, GSTO1, SLC25A13, AKR1A1, ARPP19, SDS |
819 | GO:0006094 | 0.00 | 3.37 | 19.07 | 34 | 51 | gluconeogenesis | ALDOB, ALDOC, ATF4, CRY1, ENO2, ENO3, G6PC, GAPDH, GCG, KAT2A, GOT1, GOT2, GPD1, GPD2, INS, MDH1, MDH2, PCK1, PCK2, PFKFB1, PGAM1, PGAM2, PGK1, PGM1, PRKACB, PRKACG, RANBP2, SLC25A1, OGT, SLC25A12, KAT2B, SLC25A13, ARPP19, SDS |
820 | GO:2001237 | 0.02 | 3.37 | 5.59 | 10 | 15 | negative regulation of extrinsic apoptotic signaling pathway | ACVR1, CTTN, IGF1, ITGAV, RPS6KB1, SCG2, NRP1, RB1CC1, PSME3, ZMYND11 |
821 | GO:0042990 | 0.00 | 3.37 | 17.95 | 32 | 48 | regulation of transcription factor import into nucleus | AGTR2, BCL3, CD36, CDH1, CYLD, EDA, HCLS1, IL1B, IL10, IL12B, IL18, SMAD3, TONSL, PRDX1, PPM1A, PPM1B, PPP3R1, PRKCQ, SLC9A1, TRIP6, AKAP1, DYRK2, TNFSF14, HDAC3, AKAP6, LITAF, KEAP1, TACC3, CREB3, CHERP, RBCK1, EDAR |
822 | GO:0051149 | 0.00 | 3.37 | 11.21 | 20 | 30 | positive regulation of muscle cell differentiation | ABL1, BCL2, BMP4, BNIP2, CAV3, CD53, CDC42, CDH15, CTH, CTNNA1, CTNNA2, NRG1, RBPJ, NTN3, RBM4, SMARCD3, CAMK1, AKAP6, GDF15, MAML1 |
823 | GO:0050886 | 0.00 | 3.37 | 8.96 | 16 | 24 | endocrine process | AVPR1B, AVPR2, CTSZ, CYBA, ACE, DRD3, DRD5, EDN3, F2R, F2RL1, GJA5, KRAS, OXTR, PCSK5, ATP6AP2, CORIN |
824 | GO:0002824 | 0.00 | 3.37 | 15.71 | 28 | 42 | positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | ANXA1, C3, CD4, CD28, CD80, FCER1G, FCER2, HLX, HPX, IFNG, IL1B, IL12B, P2RX7, PRKCQ, PRKCZ, PVR, XCL1, SLC11A1, STAT6, TRAF2, TNFSF4, UNG, WHSC1, FZD5, RIPK2, IL27RA, TNFSF13B, MALT1 |
825 | GO:1901343 | 0.00 | 3.37 | 15.71 | 28 | 42 | negative regulation of vasculature development | ADRB2, ANGPT2, APOH, KLK3, ADGRB1, ADGRB2, BMP4, KRIT1, COL4A3, CX3CR1, DCN, GTF2I, HHEX, HRG, FOXO4, SERPINE1, PDE3B, SERPINF1, PF4, PTGER4, PTN, PTPRM, SPARC, STAT1, ITGB1BP1, KLF4, SEMA3E, SPINK5 |
826 | GO:0006970 | 0.02 | 3.37 | 5.60 | 10 | 15 | response to osmotic stress | AKT2, ATF2, TSC22D3, PTK2B, HNMT, PCP4, RAC1, SLC2A1, SORD, TSC22D2 |
827 | GO:0006026 | 0.00 | 3.37 | 14.59 | 26 | 39 | aminoglycan catabolic process | CD44, CHIT1, VCAN, CSPG4, DCN, GPC4, GALNS, GPC3, GLB1, GUSB, HEXA, HEXB, HMMR, IDS, IDUA, LUM, OMD, OGN, OVGP1, SDC2, SDC4, SGSH, SLC9A1, SDC3, GPC6, KERA |
828 | GO:0007492 | 0.00 | 3.37 | 14.59 | 26 | 39 | endoderm development | BMPR1A, COL5A2, COL6A1, COL11A1, COL12A1, DUSP1, DUSP4, DUSP5, EXT1, GATA4, GATA6, HHEX, ONECUT1, HOXC11, ITGA4, ITGA5, ITGAV, LAMA3, SMAD3, OTX2, PAX9, PTHLH, SOX2, VTN, HMGA2, CTR9 |
829 | GO:0016525 | 0.00 | 3.37 | 14.59 | 26 | 39 | negative regulation of angiogenesis | ADRB2, ANGPT2, APOH, KLK3, ADGRB1, ADGRB2, KRIT1, COL4A3, CX3CR1, DCN, GTF2I, HHEX, HRG, FOXO4, SERPINE1, PDE3B, SERPINF1, PF4, PTN, PTPRM, SPARC, STAT1, ITGB1BP1, KLF4, SEMA3E, SPINK5 |
830 | GO:0046148 | 0.01 | 3.37 | 7.84 | 14 | 21 | pigment biosynthetic process | ALAD, ALAS1, ALAS2, APRT, TSPO, COX15, CPOX, HMBS, HPRT1, SLC11A2, SHMT1, SOX2, UROS, AP3D1 |
831 | GO:0002262 | 0.02 | 3.37 | 5.60 | 10 | 15 | myeloid cell homeostasis | ANXA1, BAX, FANCC, FCER1G, IFNG, KITLG, PDE4B, SOD1, ADAM17, BCL2L11 |
832 | GO:0048678 | 0.04 | 3.36 | 4.48 | 8 | 12 | response to axon injury | ARG1, BAX, DPYSL3, FGFR3, KCNK2, NTRK1, RANGAP1, SOD1 |
833 | GO:0035249 | 0.04 | 3.36 | 4.48 | 8 | 12 | synaptic transmission, glutamatergic | ADRB2, CACNA1A, CACNB4, CDH8, CLCN3, GRID2, P2RX1, PARK2 |
834 | GO:0045453 | 0.02 | 3.36 | 5.60 | 10 | 15 | bone resorption | ADRB2, TPP1, CTSK, PTK2B, IHH, RAC1, RAC2, RAB7A, GPR55, RAB3D |
835 | GO:0086065 | 0.01 | 3.36 | 7.85 | 14 | 21 | cell communication involved in cardiac conduction | ATP1A1, ATP1A2, ATP1A3, CALM1, CALM3, CASQ2, DSC2, DSP, HRC, KCNQ1, PDE4D, NUP155, HCN4, TRDN |
836 | GO:0050885 | 0.00 | 3.36 | 12.34 | 22 | 33 | neuromuscular process controlling balance | AARS, ABL1, ABL2, ADCY5, ALDH1A3, APLP2, APP, ATP2B2, BCR, CACNA1A, TPP1, GAA, GM2A, HEXB, RAC3, SLC1A3, SOX2, TNR, CLRN1, CNTNAP1, NRXN1, IGDCC3 |
837 | GO:0010623 | 0.04 | 3.36 | 4.48 | 8 | 12 | developmental programmed cell death | DNASE1L3, FGF4, B4GALT1, NTRK1, PPP2R1B, PAX8, FZD5, BCL2L11 |
838 | GO:0030521 | 0.04 | 3.36 | 4.48 | 8 | 12 | androgen receptor signaling pathway | BRCA1, CCNE1, SCGB2A1, RAN, RB1, UBE3A, NRIP1, NR1I3 |
839 | GO:0002718 | 0.00 | 3.36 | 11.22 | 20 | 30 | regulation of cytokine production involved in immune response | ANGPT1, APOA1, BST2, BTK, CD36, CLC, F2RL1, FCER1G, FFAR3, IFNA2, IL10, PRKCZ, XCL1, TRAF2, TNFSF4, FZD5, ATG5, TRIL, SPON2, MALT1 |
840 | GO:0021766 | 0.00 | 3.36 | 11.22 | 20 | 30 | hippocampus development | ANXA3, BBS2, BBS4, CDK6, DCX, EMX2, EPHA5, EZH1, KCNA1, OGDH, RELN, PTEN, PTPRS, RARA, SRD5A1, SRF, TP73, TSC1, USP9X, ZEB2 |
841 | GO:0003009 | 0.02 | 3.36 | 5.60 | 10 | 15 | skeletal muscle contraction | ADRB2, CHUK, EEF2, GAA, RPS6KB1, TNNC2, TNNC1, TNNI2, TNNI3, TNNT1 |
842 | GO:0030850 | 0.01 | 3.36 | 6.73 | 12 | 18 | prostate gland development | ALOX15B, ANXA1, BMP4, CD44, IGF1R, SERPINF1, SERPINB5, RARA, RXRA, STK11, TP63, FEM1B |
843 | GO:0006144 | 0.00 | 3.36 | 8.98 | 16 | 24 | purine nucleobase metabolic process | ACPP, ADSL, ADSS, AMPD1, AMPD2, AOX1, APRT, CAT, DPYD, GPX1, HPRT1, IL1B, IMPDH1, IMPDH2, PFAS, SHMT1 |
844 | GO:0010596 | 0.00 | 3.36 | 8.98 | 16 | 24 | negative regulation of endothelial cell migration | ACVRL1, AGTR2, ANGPT2, APOH, KRIT1, DCN, HRG, SERPINF1, PTPRM, SP100, STC1, NR2F2, ITGB1BP1, KLF4, SLIT2, CXCL13 |
845 | GO:0010862 | 0.00 | 3.36 | 8.98 | 16 | 24 | positive regulation of pathway-restricted SMAD protein phosphorylation | ACVR1, ACVR2A, ACVRL1, BMP1, BMP3, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, DAB2, GDF9, INHA, SDCBP, TTK, GDF15 |
846 | GO:0015991 | 0.00 | 3.36 | 8.98 | 16 | 24 | ATP hydrolysis coupled proton transport | ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP1A4, ATP4A, ATP5G2, ATP5G3, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, ATP6V0D1 |
847 | GO:0019222 | 0.02 | 3.36 | 5.32 | 10 | 16 | regulation of metabolic process | ACLY, ASIP, CLCN3, CYBA, FFAR3, PRCP, TYRP1, STK17A, SMG7, FBLN5 |
848 | GO:0060487 | 0.02 | 3.36 | 5.61 | 10 | 15 | lung epithelial cell differentiation | ASCL1, EYA1, GATA6, FOXA2, RBPJ, IL13, NUMA1, SOX9, AIMP2, NUMB |
849 | GO:0048641 | 0.04 | 3.36 | 4.48 | 8 | 12 | regulation of skeletal muscle tissue development | DDX5, TSC22D3, S100B, SIX1, TWIST1, HDAC4, NR1D2, USP19 |
850 | GO:0070266 | 0.04 | 3.36 | 4.48 | 8 | 12 | necroptotic process | CYLD, PYGL, TRAF2, UBB, TRADD, TNFSF10, TNFRSF10B, TNFRSF10A |
851 | GO:0014003 | 0.04 | 3.36 | 4.48 | 8 | 12 | oligodendrocyte development | ASCL1, CD9, LPAR1, EIF2B1, SOX11, EIF2B3, EIF2B2, EIF2B5 |
852 | GO:0009083 | 0.01 | 3.36 | 7.85 | 14 | 21 | branched-chain amino acid catabolic process | ACADSB, ALDH9A1, AUH, BCAT1, BCKDHA, DBT, HSD17B10, HMGCL, IVD, ALDH6A1, SHMT1, BBOX1, BCKDK, HIBADH |
853 | GO:0032964 | 0.01 | 3.36 | 7.85 | 14 | 21 | collagen biosynthetic process | ARG1, BMP4, SERPINH1, COL1A1, CTGF, F2, F2R, IHH, CIITA, UCN, SERPINB7, ADAMTS3, TRAM2, RAPGEF3 |
854 | GO:0043471 | 0.01 | 3.36 | 7.85 | 14 | 21 | regulation of cellular carbohydrate catabolic process | ADRA1B, ARNT, GPD1, HIF1A, IGF1, INS, P2RX7, PGAM1, PGAM2, PRKAA1, PRKAG1, STAT3, OGT, HDAC4 |
855 | GO:0050829 | 0.01 | 3.36 | 7.85 | 14 | 21 | defense response to Gram-negative bacterium | ADM, APP, BPI, CD4, F2RL1, FCN2, IL12B, SERPINE1, S100A7, SELP, SLC11A1, TAC1, VIP, CD160 |
856 | GO:0060338 | 0.01 | 3.36 | 7.85 | 14 | 21 | regulation of type I interferon-mediated signaling pathway | ADAR, UBE2K, HSP90AB1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, PTPN1, PTPN6, STAT1, STAT2, SOCS3, CDC37 |
857 | GO:0007205 | 0.01 | 3.36 | 6.73 | 12 | 18 | protein kinase C-activating G-protein coupled receptor signaling pathway | CCK, CHRM1, CISH, DGKA, DGKB, DGKQ, EDNRA, F2R, GRM1, DGKZ, DGKI, PICK1 |
858 | GO:0010611 | 0.01 | 3.36 | 6.73 | 12 | 18 | regulation of cardiac muscle hypertrophy | CAV3, CDK9, IGF1, P2RX4, RGS2, SLC9A1, TRPC3, AKAP1, PDE5A, CTDP1, AKAP6, AKAP13 |
859 | GO:0032467 | 0.01 | 3.36 | 6.73 | 12 | 18 | positive regulation of cytokinesis | CDC42, DRD3, OPN1MW, PRKCE, OPN1LW, SPAST, SVIL, CUL3, AURKB, KIF3B, GIPC1, CIT |
860 | GO:0033081 | 0.01 | 3.36 | 6.73 | 12 | 18 | regulation of T cell differentiation in thymus | BMP4, CAMK4, CDKN2A, EGR3, ERBB2, IHH, IL1B, SOD1, SOS1, SOS2, ZEB1, FOXN1 |
861 | GO:0035590 | 0.01 | 3.36 | 6.73 | 12 | 18 | purinergic nucleotide receptor signaling pathway | P2RX1, P2RX3, P2RX4, P2RX5, P2RX7, P2RY1, P2RY2, P2RY4, P2RY6, P2RY11, PTAFR, P2RY14 |
862 | GO:0050701 | 0.01 | 3.36 | 6.73 | 12 | 18 | interleukin-1 secretion | ABCA1, APOA1, CASP1, CASP5, CD36, F2RL1, GAS6, IFNG, P2RX7, PTGER4, S100A13, TRIM16 |
863 | GO:1902042 | 0.01 | 3.36 | 6.73 | 12 | 18 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | BRCA1, FGA, FGG, GPX1, HGF, ICAM1, SERPINE1, RAF1, TNFAIP3, PEA15, CFLAR, ARHGEF2 |
864 | GO:1902932 | 0.01 | 3.36 | 6.73 | 12 | 18 | positive regulation of alcohol biosynthetic process | BMP6, ACSL3, HRH1, IFNG, IL1B, NTSR1, P2RY1, PRKAA1, PTAFR, SNCA, SREBF1, ABCG1 |
865 | GO:0002825 | 0.02 | 3.35 | 5.61 | 10 | 15 | regulation of T-helper 1 type immune response | ANXA1, CD80, HLX, IL12B, XCL1, SLC11A1, TNFSF4, RIPK2, IL1RL1, IL27RA |
866 | GO:0016601 | 0.02 | 3.35 | 5.61 | 10 | 15 | Rac protein signal transduction | ARF6, DNM2, EPS8, KRAS, OGT, WASF1, ELMO1, FARP2, ABI2, WASF2 |
867 | GO:0030199 | 0.02 | 3.35 | 5.61 | 10 | 15 | collagen fibril organization | SERPINH1, COL1A1, COL3A1, COL5A2, COL11A1, COL12A1, LUM, P4HA1, ADAMTS3, ADAMTS2 |
868 | GO:0031112 | 0.02 | 3.35 | 5.61 | 10 | 15 | positive regulation of microtubule polymerization or depolymerization | ARL2, CAV3, RGS2, RPS3, CLIP1, SPAST, KATNB1, TUBGCP3, TUBGCP2, STMN2 |
869 | GO:0045622 | 0.02 | 3.35 | 5.61 | 10 | 15 | regulation of T-helper cell differentiation | ANXA1, CD80, CD86, HLX, IL12B, PRKCZ, RARA, TNFSF4, RIPK2, TNFSF18 |
870 | GO:0050873 | 0.02 | 3.35 | 5.61 | 10 | 15 | brown fat cell differentiation | ADRB2, BNIP3, INS, ALDH6A1, RGS2, SLC2A4, UCP1, PEX11A, ZNF516, ARL4A |
871 | GO:0051894 | 0.02 | 3.35 | 5.61 | 10 | 15 | positive regulation of focal adhesion assembly | COL16A1, HRG, KDR, SMAD3, PTPRJ, RAC1, S100A10, SDC4, TSC1, ITGB1BP1 |
872 | GO:0071470 | 0.02 | 3.35 | 5.61 | 10 | 15 | cellular response to osmotic stress | BDKRB2, TSPO, RELB, SCN2A, SLC2A4, SLC6A12, SLC12A1, ARHGEF2, OXSR1, SLC12A6 |
873 | GO:0086005 | 0.02 | 3.35 | 5.61 | 10 | 15 | ventricular cardiac muscle cell action potential | CAV3, DSC2, DSP, GJA5, KCNE1, KCNH2, KCNQ1, RYR2, SCN5A, KCNE2 |
874 | GO:1990182 | 0.02 | 3.35 | 5.61 | 10 | 15 | exosomal secretion | IFNG, RAB27A, SDC4, SDCBP, TSG101, RAB7A, STAM, RAB11A, PDCD6IP, COPS5 |
875 | GO:0001759 | 0.04 | 3.35 | 4.49 | 8 | 12 | organ induction | BMP4, FGF3, HOXC11, HOXD11, SIX1, WNT2, WNT2B, SPRY1 |
876 | GO:0002076 | 0.04 | 3.35 | 4.49 | 8 | 12 | osteoblast development | ACHE, BGLAP, RUNX2, ESR1, JUND, SMAD3, PTHLH, HDAC4 |
877 | GO:0002701 | 0.04 | 3.35 | 4.49 | 8 | 12 | negative regulation of production of molecular mediator of immune response | ANGPT1, APOA1, BST2, IFNA2, IL10, IL13RA2, XCL1, SPINK5 |
878 | GO:0006337 | 0.04 | 3.35 | 4.49 | 8 | 12 | nucleosome disassembly | HMGA1, SET, SMARCA4, SMARCC2, SMARCD1, SMARCD3, SMARCE1, SUPT16H |
879 | GO:0006855 | 0.04 | 3.35 | 4.49 | 8 | 12 | drug transmembrane transport | ATP8B1, SLC18A1, SLC22A1, SLC22A3, SLC22A2, SLC22A5, ABCG2, EBP |
880 | GO:0007271 | 0.04 | 3.35 | 4.49 | 8 | 12 | synaptic transmission, cholinergic | ACHE, CACNA1A, CHRM1, CHRM3, CHRNB2, CHRNB4, IFNG, TAC1 |
881 | GO:0007435 | 0.04 | 3.35 | 4.49 | 8 | 12 | salivary gland morphogenesis | CDC42, EDA, FGF7, HGF, LAMA5, NRP1, SEMA3A, EDAR |
882 | GO:0008045 | 0.04 | 3.35 | 4.49 | 8 | 12 | motor neuron axon guidance | CHN1, EGR2, ERBB2, ETV4, SEMA3F, NRP1, SLIT2, SEMA3A |
883 | GO:0015669 | 0.04 | 3.35 | 4.49 | 8 | 12 | gas transport | AQP5, HBA2, HBM, HBD, HBE1, HBG1, HBQ1, RHAG |
884 | GO:0019430 | 0.04 | 3.35 | 4.49 | 8 | 12 | removal of superoxide radicals | CD36, DHFR, FANCC, PRDX1, SOD1, SOD2, RGN, FBLN5 |
885 | GO:0032800 | 0.04 | 3.35 | 4.49 | 8 | 12 | receptor biosynthetic process | ACHE, HIF1A, IL10, ITGAV, NR2F1, HDAC6, CNPY2, SEC24A |
886 | GO:0035115 | 0.04 | 3.35 | 4.49 | 8 | 12 | embryonic forelimb morphogenesis | ALX3, RUNX2, EN1, HOXD9, HOXD11, TWIST1, RECK, ALDH1A2 |
887 | GO:0035116 | 0.04 | 3.35 | 4.49 | 8 | 12 | embryonic hindlimb morphogenesis | ALX3, BMP4, FGF4, GPC3, GNAS, AFF3, RARB, TWIST1 |
888 | GO:0035574 | 0.04 | 3.35 | 4.49 | 8 | 12 | histone H4-K20 demethylation | HIST1H4I, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L |
889 | GO:0035909 | 0.04 | 3.35 | 4.49 | 8 | 12 | aorta morphogenesis | JAG1, COL3A1, EYA1, HES1, RBPJ, SIX1, SRF, SEC24B |
890 | GO:0042219 | 0.04 | 3.35 | 4.49 | 8 | 12 | cellular modified amino acid catabolic process | AHCY, CBS, CCBL1, DIO3, GOT2, ALDH4A1, KYNU, ALDH1L1 |
891 | GO:0043949 | 0.04 | 3.35 | 4.49 | 8 | 12 | regulation of cAMP-mediated signaling | GNAI1, GNAS, PDE3B, PDE4A, PF4, RGS2, RAPGEF2, PDE10A |
892 | GO:0045923 | 0.04 | 3.35 | 4.49 | 8 | 12 | positive regulation of fatty acid metabolic process | AKT2, ANXA1, APOA1, AVP, GHSR, TWIST1, NR1H2, RGN |
893 | GO:0046174 | 0.04 | 3.35 | 4.49 | 8 | 12 | polyol catabolic process | GK2, GPD2, IMPA1, INPP1, NTSR1, PTEN, SORD, SYNJ1 |
894 | GO:0051491 | 0.04 | 3.35 | 4.49 | 8 | 12 | positive regulation of filopodium assembly | DPYSL3, GPM6A, PALM, PRKCQ, RALA, CCL21, FSCN1, SRF |
895 | GO:0052312 | 0.04 | 3.35 | 4.49 | 8 | 12 | modulation of transcription in other organism involved in symbiotic interaction | CHD1, EP300, JUN, NTRK3, REST, SMARCA4, SP1, HMGA2 |
896 | GO:0060261 | 0.04 | 3.35 | 4.49 | 8 | 12 | positive regulation of transcription initiation from RNA polymerase II promoter | CREB1, PSMC1, PSMC2, PSMC3, PSMC4, SRF, HNF1A, IKZF1 |
897 | GO:0061037 | 0.04 | 3.35 | 4.49 | 8 | 12 | negative regulation of cartilage development | BMP4, EFEMP1, PTHLH, RARA, RARB, SOX9, WNT11, ADAMTS7 |
898 | GO:1901385 | 0.04 | 3.35 | 4.49 | 8 | 12 | regulation of voltage-gated calcium channel activity | CACNB3, CACNB4, CALM1, CALM3, PDE4B, S100A1, KCNE2, KCNE3 |
899 | GO:1901623 | 0.04 | 3.35 | 4.49 | 8 | 12 | regulation of lymphocyte chemotaxis | ADAM10, PTK2B, S100A7, XCL1, ADAM17, TNFSF14, CXCL14, CXCL13 |
900 | GO:0006415 | 0.00 | 3.30 | 24.31 | 43 | 65 | translational termination | EIF5A, ETF1, FAU, RPL10A, UPF1, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, RPL14, RPL23, RPL35 |
901 | GO:0038061 | 0.00 | 3.30 | 22.04 | 39 | 59 | NIK/NF-kappaB signaling | ALK, BIRC2, BIRC3, CHUK, PPP4C, EIF2AK2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, RELB, RPS3, SKP1, UBB, CUL1, CPNE1, UBA3, PSMF1, PSMD6, PSME3, PSMD14 |
902 | GO:0008584 | 0.00 | 3.29 | 18.65 | 33 | 50 | male gonad development | AMHR2, CCND1, BCL2, BCL2L1, BOK, COL9A3, CTNNA1, ERCC1, FANCA, FSHR, GATA6, HSD17B10, HMGCS1, ING2, INHA, INSL3, KIT, KITLG, PRKACG, RRM1, SRD5A1, STAR, TMF1, UBB, WNT2B, CSDE1, AKR1C3, ADAM15, EIF2S2, REC8, BCL2L11, FSTL3, PRDX4 |
903 | GO:0060326 | 0.00 | 3.28 | 46.00 | 81 | 123 | cell chemotaxis | ADAM10, AGTR1, ANXA1, CCR5, CX3CR1, CXADR, HBEGF, LPAR1, EDN3, EDNRA, EGR3, EPHA2, EPHB1, F2RL1, F7, PTK2B, FCER1G, FGF4, FLT1, GAS6, CXCL1, CXCL3, HGF, NR4A1, HRH1, HRG, HSPB1, IFNG, IL1B, IL10, ITGA1, ITGA9, KDR, KIT, SERPINE1, PDE4B, PDE4D, PF4, PF4V1, PIK3CB, PRKCD, PRKD1, PRKCQ, RAB13, RAC1, RAC2, RPS19, S100A7, S100A8, S100A9, S100A12, SAA4, CCL20, CCL21, CCL22, CCL24, CCL25, CXCL6, CXCL5, XCL1, CX3CL1, SFTPD, XCL2, ADAM17, VAV1, VCAM1, VEGFB, VEGFC, SCG2, ARHGEF5, TNFSF14, NRP1, TNFSF18, SEMA5A, SLIT2, CXCL14, BCAR1, VAV3, CREB3, CXCL13, CORO1A |
904 | GO:0046661 | 0.00 | 3.27 | 31.79 | 56 | 85 | male sex differentiation | ACVR2A, NR0B1, AMHR2, ATRX, BAX, CCND1, BCL2, BCL2L1, BMP6, BMPR1A, BOK, COL9A3, CTNNA1, CTSV, DHCR24, ERCC1, ESR1, FANCA, FSHB, FSHR, NR5A1, GATA4, GATA6, HSD17B10, HMGCS1, ICAM1, ING2, INHA, INSL3, KIT, KITLG, NTRK1, PRKACG, RAB13, RARA, RRM1, SOX2, SOX9, SRD5A1, SRY, STAR, STAT5B, TMF1, UBB, WNT2B, CSDE1, AKR1C3, ADAM15, EIF2S2, REC8, BCL2L11, AKAP9, FSTL3, CITED2, SEMA3A, PRDX4 |
905 | GO:1900046 | 0.00 | 3.26 | 17.58 | 31 | 47 | regulation of hemostasis | ABAT, ADRB2, ALOX12, ANXA5, APOH, SERPING1, CD36, F2, F2R, F2RL1, F3, F7, FAP, FCER1G, FGA, FGG, GP1BA, FOXA2, HRG, KLKB1, KNG1, KRT1, SERPINE1, SERPINB2, PRKCD, PRKCQ, PROC, S100A9, SELP, USF1, VTN |
906 | GO:0001932 | 0.00 | 3.26 | 37.51 | 67 | 104 | regulation of protein phosphorylation | ACVR1, ACVR2A, ACVRL1, AKT2, APOA1, ARR3, AVP, BCL2, BMPR1A, BMPR2, CCK, CD3E, CD80, CNTF, CREBL2, CRH, CSNK1D, CTF1, DAB2, F2, FLT3LG, HCLS1, UBE2K, HPX, HRC, HRG, HES1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IL13, IL15, IL18, ISL1, ITGA5, ENPP2, PFN2, PRKD1, PTGER4, RAC1, RAD51, SOX9, SPN, TNFRSF1A, TTK, VEGFC, VTN, WNT1, CDK2AP1, BCAR3, TNFRSF18, TNFSF18, ARHGEF2, CRLF1, EIF2AK3, BAG4, RB1CC1, RAD50, TNK2, RAPGEF3, MAD2L2, IL24, CHEK2 |
907 | GO:0033273 | 0.00 | 3.26 | 14.15 | 25 | 38 | response to vitamin | ATP2B1, BGLAP, TSPO, CD4, CYP24A1, F7, GAS6, HLCS, HMBS, IL1B, IL15, ITGB1, OTC, PENK, PIM1, PTN, SPARC, STC1, TYR, FGF23, TRIM24, KYNU, ADAMTS1, SETDB1, PEMT |
908 | GO:0030104 | 0.00 | 3.26 | 16.46 | 29 | 44 | water homeostasis | ADCY3, ADCY5, ADCY6, ADCY9, ALOX12, ANXA7, AVP, AVPR2, FLG, GHRHR, GNAS, SFN, IGF1, KRT1, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, SCNN1A, SCNN1B, SCNN1G, SLC6A12, SRF, WFS1, TP63, RAB11A, CLDN1 |
909 | GO:0090277 | 0.00 | 3.26 | 16.46 | 29 | 44 | positive regulation of peptide hormone secretion | ABAT, BAD, BLK, CD38, CFTR, CRH, FGA, FGG, GCG, GHRH, GHRHR, GLUD1, GLUL, GPLD1, GPR27, FFAR1, HIF1A, INS, ISL1, KISS1, OXCT1, PFKFB2, PRKCE, PTGER4, TRPM2, UCN, ARHGEF7, C2CD2L, CAPN10 |
910 | GO:0034340 | 0.00 | 3.25 | 15.33 | 27 | 41 | response to type I interferon | ADAR, BST2, UBE2K, HSP90AB1, IFIT1, IFIT3, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IRF1, IRF2, IRF5, ISG20, OAS2, OAS3, PTPN1, PTPN6, SHMT2, SP100, STAT1, STAT2, SOCS3, IFITM3, IFITM2, CDC37 |
911 | GO:0048771 | 0.00 | 3.24 | 11.90 | 21 | 32 | tissue remodeling | ADRB2, ANXA1, ARG1, CAPN1, TPP1, CSPG4, CTSK, EPHA2, F2R, PTK2B, GJA5, HIF1A, IGFBP5, IHH, IL1A, RAC1, RAC2, SLC34A1, RAB7A, GPR55, RAB3D |
912 | GO:0006757 | 0.00 | 3.24 | 14.21 | 25 | 38 | ATP generation from ADP | ALDOB, ALDOC, ARNT, ENO2, ENO3, GAPDH, GPD1, HIF1A, IGF1, INS, LDHA, OGDH, P2RX7, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PGM1, PPP2R5D, PRKAA1, PRKAG1, STAT3, OGT, HDAC4 |
913 | GO:0048010 | 0.00 | 3.23 | 57.13 | 100 | 153 | vascular endothelial growth factor receptor signaling pathway | ACTB, ACTG1, ANGPT1, ARAF, AXL, BMPR2, CALM1, CALM3, CAMK2A, CDC42, CSF2RB, CTNNA1, CYBA, CYBB, HBEGF, DUSP5, ERBB2, EREG, PTK2B, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FLT4, FYN, GRB2, GRIN2A, NRG1, HSPB1, HSP90AA1, IL2RA, ITGAV, ITPR1, ITPR2, KDR, KIT, KRAS, MARK3, KITLG, PEBP1, PIK3CB, PPP5C, PRKCD, PRKD1, PRKCZ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTK2, PTPRA, RAC1, RAF1, RASA2, SHB, SHC1, SOS1, UBB, VAV1, FGF23, CUL3, PEA15, NRP2, NRP1, PSMF1, NRG2, BCAR1, RAPGEF2, ELMO1, PSMD6, RBX1, ABI1, AKAP9, RASA4, WASF2, PSME3, PSMD14, VAV3, BAIAP2, FRS3 |
914 | GO:0072507 | 0.00 | 3.22 | 81.53 | 142 | 218 | divalent inorganic cation homeostasis | ABL1, ABL2, ADCY5, ADM, ADRA1B, AGTR1, ANXA6, ANXA7, APP, ATP1A2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP6V1B1, ATP7B, AVP, AVPR1B, BAX, BCL2, BDKRB2, BMP4, CACNA1A, CACNB4, CALCR, CALM1, CALM3, CASQ1, CASQ2, CAV3, CD4, CD36, CD38, CD52, CCR3, CCR5, CCR8, CYBA, DDIT3, DIAPH1, DRD3, DRD5, S1PR1, LPAR1, S1PR3, EDN3, EDNRA, ESR1, F2, F2R, F2RL1, PTK2B, GALR1, GLP1R, GNA15, GNAT2, GNB1, GNG3, CCR10, XCR1, UTS2R, GRINA, GRM1, GSTM2, GTF2I, HEXB, HRC, HTR2C, IL1B, IL13, ITGB1, ITPR1, ITPR2, KCNA1, KCNK3, KDR, KISS1, KNG1, NTSR1, OXTR, P2RX3, P2RX4, P2RX5, P2RX7, P2RY1, P2RY2, P2RY4, PARK2, PDE4D, PIK3CB, PLN, PRKCE, PRKD1, PSEN1, PTPN6, PYGM, RAP1GDS1, RYR1, RYR2, RYR3, S100A8, S100A9, CCL21, XCL1, SLC8A3, SLC11A1, SNCA, STC1, TAC1, TNNI3, TPT1, HSP90B1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, TRPV1, WFS1, SLC30A2, SLC30A3, SLC30A4, CSRP3, S1PR4, TRIM24, INPP4B, AP3D1, TRPA1, RGN, SLC24A1, VAPB, GSTO1, AKAP6, ATG5, TRDN, CIB2, CHERP, CXCL13, SCGN, CCR9, IMMT, CORO1A |
915 | GO:0034446 | 0.00 | 3.22 | 11.95 | 21 | 32 | substrate adhesion-dependent cell spreading | ABL1, AXL, EFNA1, EPHA1, EPHB3, FBLN1, ILK, ITGA4, ITGAV, LAMA5, TACSTD2, PTK2, RAB1A, ST6GAL1, TYRO3, FZD4, FZD7, ITGA8, ITGB1BP1, FERMT2, BVES |
916 | GO:0042770 | 0.00 | 3.22 | 32.54 | 57 | 87 | signal transduction in response to DNA damage | ABL1, ATM, ATR, ATRX, BCL3, BID, BRCA1, BRCA2, CASP9, CD44, CDC5L, CDK2, CDKN1A, CDKN2A, GADD45A, DDX5, DYRK1A, GRB2, HIC1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, SNAI1, SP100, TP73, TWIST1, UBB, WNT1, SMC1A, TP63, CRADD, PSMF1, EEF1E1, PSMD6, PSME3, PSMD14, MAD2L2, CHEK2 |
917 | GO:0000184 | 0.00 | 3.19 | 29.17 | 51 | 78 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | EIF4G1, ETF1, FAU, EIF3E, RPL10A, PPP2R1A, PPP2R2A, UPF1, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, RPL14, RPL23, DHX34, EIF4A3, SMG7, RBM8A, RNPS1, RPL35 |
918 | GO:0050919 | 0.00 | 3.19 | 10.85 | 19 | 29 | negative chemotaxis | APOA1, EFNA5, EPHA7, NRG1, ITGAV, RYK, SEMA3F, SLIT3, SEMA3B, SEMA5A, SLIT2, SEMA3E, SEMA3A, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, NRG3 |
919 | GO:0051402 | 0.01 | 3.19 | 8.53 | 15 | 23 | neuron apoptotic process | APAF1, APP, BID, BNIP3, BOK, ESR1, GAPDH, GPX1, GRID2, RB1, SCN2A, SIAH1, TP63, AATK, SIGMAR1 |
920 | GO:0046777 | 0.00 | 3.19 | 33.16 | 58 | 89 | protein autophosphorylation | ALK, ATM, ATR, BCR, CAMK4, CAMK2A, CLK1, CLK3, CSF1R, CSNK1G2, DAPK3, DCX, DYRK1A, EIF2S1, EPHA1, EPHA7, EPHA8, EPHB1, EPHB3, ERBB2, ERN1, FGFR3, FGFR4, FLT1, FLT3, FLT4, GFRA2, INSRR, IRAK1, JUN, KIT, MAP3K11, NTRK1, NTRK2, NTRK3, PHKA1, PIM1, PRKD1, EIF2AK2, PRKX, AURKA, CDKL5, STK10, STK11, TYRO3, VRK1, VRK2, MAPKAPK5, STK16, RIPK1, TRIM24, AURKB, STK17B, EIF2AK3, SLK, STK25, PIM2, CHEK2 |
921 | GO:0001889 | 0.00 | 3.18 | 26.90 | 47 | 72 | liver development | AK2, AK4, ALDH9A1, ALDOB, ANXA1, ARF6, ARG1, ASS1, CCND1, BMP4, CCNE1, CPS1, GATA6, HGF, HHEX, HLX, HMGCL, HMGCS1, HMGCS2, ONECUT1, HNRNPD, HES1, IFNG, JARID2, JUN, LIPC, SMAD3, OTC, PHF2, PTN, QDPR, RARA, RPS6KA1, RXRA, SOX9, SP1, SRD5A1, STAT5B, TNFAIP3, WNT1, CUL3, ALDH1A2, ONECUT2, RB1CC1, CITED2, ATG7, SEC63 |
922 | GO:0019882 | 0.00 | 3.18 | 32.07 | 56 | 86 | antigen processing and presentation | AZGP1, CD1B, CD8A, CD36, CTSH, CYBA, CYBB, ACE, FCGR1A, FCGR1B, FCGRT, ICAM1, IFNG, ITGAV, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, RAB3B, RAB4A, RAB5B, RAB6A, RAB27A, RELB, CCL21, SLC11A1, UBB, AP3B1, AP3D1, RAB33A, PSMF1, PSMD6, PSME3, PSMD14, RAB10, SEC61B, RAB32, RAB35 |
923 | GO:0014047 | 0.00 | 3.17 | 9.72 | 17 | 26 | glutamate secretion | AVP, CCK, GLS, IL1B, NTRK2, NTSR1, P2RX7, SLC1A3, SLC1A6, SLC1A7, SNAP25, SNCA, STXBP1, SYT1, TRPV1, GIPC1, CPLX1 |
924 | GO:0032370 | 0.00 | 3.17 | 9.72 | 17 | 26 | positive regulation of lipid transport | ABCA1, BMP6, CRH, GALR1, IL1B, NTSR1, P2RX4, P2RX7, P2RY2, PRKCD, TAC1, TMF1, NR1H2, LIPG, ABCG1, ABCA7, ATP8A1 |
925 | GO:0060395 | 0.00 | 3.17 | 9.72 | 17 | 26 | SMAD protein signal transduction | BMP1, BMP3, BMP4, BMP6, BMP8B, GATA4, GDF9, INHA, JUN, SMAD1, SMAD3, SMAD9, CITED1, VIM, SLC33A1, GDF15, RBM14 |
926 | GO:0030155 | 0.00 | 3.17 | 22.72 | 40 | 62 | regulation of cell adhesion | ACVRL1, ADAM10, ANGPT2, ARHGAP6, ARHGDIB, BCL2, COL1A1, CLDN7, DAPK3, S1PR1, ONECUT1, ICAM1, KNG1, LAMA3, LAMA4, LAMA5, TACSTD2, ATXN3, PPP1R12A, PIK3CB, PPP2R1A, PRKX, PTEN, ST6GAL1, SIPA1, SLC9A1, SOX9, SPOCK1, SRF, TBCD, FZD4, FZD7, ADAM15, SEMA5A, ONECUT2, CYTIP, SEMA3E, SLK, NUAK1, SEMA4D |
927 | GO:0022612 | 0.01 | 3.17 | 8.57 | 15 | 23 | gland morphogenesis | BCL2, CD44, IFNG, IGF1, IGF1R, SERPINB5, PTN, RPS6KA1, RXRA, SOX9, TNFAIP3, CUL3, TP63, SLC9A3R1, FEM1B |
928 | GO:0051279 | 0.01 | 3.16 | 8.58 | 15 | 23 | regulation of release of sequestered calcium ion into cytosol | ATP1A2, CASQ1, CASQ2, CYBA, DIAPH1, PTK2B, HRC, PDE4D, PLN, PRKCE, PRKD1, PTPN6, RYR2, ATG5, CORO1A |
929 | GO:0003091 | 0.01 | 3.15 | 8.60 | 15 | 23 | renal water homeostasis | ADCY3, ADCY5, ADCY6, ADCY9, AVP, AVPR2, GNAS, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, WFS1, RAB11A |
930 | GO:0006284 | 0.01 | 3.15 | 8.60 | 15 | 23 | base-excision repair | ERCC6, FEN1, HMGA1, NTHL1, OGG1, PCNA, RFC3, RFC4, RFC5, RPA2, RPA3, UNG, HMGA2, PARG, MBD4 |
931 | GO:0006308 | 0.01 | 3.15 | 8.60 | 15 | 23 | DNA catabolic process | APAF1, BAX, CDKN2A, DFFA, DNASE1, DNASE1L1, DNASE1L2, DNASE1L3, DNASE2, ISG20, KPNA1, SETMAR, RGN, AIFM1, TATDN2 |
932 | GO:0007157 | 0.01 | 3.15 | 8.60 | 15 | 23 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | CD6, CXADR, GRID2, ICAM1, ITGA4, ITGA5, CD200, PTPRD, PVR, SELE, SELP, VCAM1, DCHS1, NRXN1, IL1RAPL1 |
933 | GO:0019083 | 0.00 | 3.15 | 28.71 | 50 | 77 | viral transcription | FAU, RPL10A, NUP88, NUP98, RANBP2, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, USF1, NUP214, AAAS, RPL14, RPL23, NUP155, NUP93, NUP50, NUPL2, RPL35 |
934 | GO:0030593 | 0.00 | 3.14 | 16.08 | 28 | 43 | neutrophil chemotaxis | CXADR, EDN3, EDNRA, FCER1G, CXCL1, CXCL3, IFNG, IL1B, ITGA1, ITGA9, PDE4B, PDE4D, RAC1, RAC2, S100A8, S100A9, S100A12, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, XCL2, VAV1, SLIT2, VAV3 |
935 | GO:0032411 | 0.00 | 3.14 | 16.08 | 28 | 43 | positive regulation of transporter activity | ATP1B3, BMP4, CALM1, CALM3, CFTR, DNM2, GSTM2, KCNJ11, NTSR1, PRKCD, RELN, PTAFR, RYR2, S100A1, SGK1, SLC9A1, SUMO1, RGN, SYNGR3, GSTO1, AKAP7, AKAP6, KCNE2, KCNE3, SGK2, AKAP9, TRDN, RAPGEF3 |
936 | GO:0030183 | 0.00 | 3.13 | 22.44 | 39 | 60 | B cell differentiation | ABL1, ATM, BAD, BAX, BCL2, BCL3, PRDM1, BTK, CR2, GPR183, EP300, PTK2B, FLT3, HHEX, ONECUT1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, RBPJ, IL10, INHA, ITGA4, ITGB1, KIT, NTRK1, PTPN6, RAG1, RAG2, STAT5B, ADAM17, TPD52, VCAM1, FZD9, HDAC4, IKZF1, MALT1 |
937 | GO:0045665 | 0.00 | 3.13 | 13.77 | 24 | 37 | negative regulation of neuron differentiation | JAG1, APP, ASCL1, CNTF, DDX6, EIF4E, FOXA2, HES1, IL1B, ISL1, ITGB1, PBX1, RAP1GAP, REST, SIX3, SOX2, SOX3, SOX9, CNTN2, TP73, TTC3, PHOX2B, OLIG2, HMG20A |
938 | GO:0030282 | 0.01 | 3.13 | 7.47 | 13 | 20 | bone mineralization | FGFR3, GPC3, IGF1, PHEX, PTN, KLF10, CLEC3B, TUFT1, WNT11, CER1, EIF2AK3, MINPP1, GPNMB |
939 | GO:0001657 | 0.00 | 3.12 | 21.32 | 37 | 57 | ureteric bud development | AGTR2, ARG2, BCL2, BMP4, CAT, CD44, EYA1, GPC3, HOXD11, HES1, ILK, LAMA5, TACSTD2, EPCAM, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, CITED1, PBX1, PSPN, RARA, RARB, SALL1, SDC4, SIX1, SOX9, WNT1, WNT11, WNT2B, PAX8, DCHS1, CRLF1, CER1, SLIT2, SPRY1 |
940 | GO:0072163 | 0.00 | 3.12 | 21.32 | 37 | 57 | mesonephric epithelium development | AGTR2, ARG2, BCL2, BMP4, CAT, CD44, EYA1, GPC3, HOXD11, HES1, ILK, LAMA5, TACSTD2, EPCAM, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, CITED1, PBX1, PSPN, RARA, RARB, SALL1, SDC4, SIX1, SOX9, WNT1, WNT11, WNT2B, PAX8, DCHS1, CRLF1, CER1, SLIT2, SPRY1 |
941 | GO:0006112 | 0.00 | 3.12 | 39.27 | 68 | 105 | energy reserve metabolic process | ACACB, ACLY, ADCY3, ADCY5, ADCY6, ADCY9, ADRA1B, ADRA2A, AKT2, ARL2, CACNA1A, CALM1, CALM3, CHRM3, CPS1, G6PC, GAA, GCG, GCGR, GLP1R, GNAS, GNB1, GNG3, GNG10, GNG11, FFAR1, GYS2, IGF1, IGF2, INS, ITPR1, ITPR2, KCNC2, KCNJ11, KCNS3, KHK, PFKFB1, PGM1, PHKA1, PHKA2, PHKB, PHKG1, PPP1R1A, PPP1R2, PPP2R5D, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PYGB, PYGL, PYGM, SLC2A1, SNAP25, STK11, STXBP1, ABCC8, SYT5, UBB, UGP2, EPM2A, DYRK2, EPM2AIP1, RAPGEF3, SORBS1, RAPGEF4 |
942 | GO:0015721 | 0.01 | 3.12 | 7.48 | 13 | 20 | bile acid and bile salt transport | ALB, AKR1C4, FABP6, ATP8B1, RXRA, SLC10A1, SLC10A2, SLCO1A2, SLC10A3, SLC9A3R1, NR1H4, SLCO1B1, SLC27A5 |
943 | GO:0042168 | 0.01 | 3.12 | 7.48 | 13 | 20 | heme metabolic process | ALAD, ALAS1, ALAS2, AMBP, BLVRA, BLVRB, TSPO, COX15, CPOX, HMBS, HPX, SLC11A2, UROS |
944 | GO:0045124 | 0.01 | 3.12 | 7.48 | 13 | 20 | regulation of bone resorption | ATP6AP1, BGLAP, CA2, CD38, CSF1R, S1PR1, FSHB, IAPP, TNFRSF11B, P2RX7, PDK4, PTGER4, TNFAIP3 |
945 | GO:0051930 | 0.01 | 3.12 | 7.48 | 13 | 20 | regulation of sensory perception of pain | ACPP, ADRB2, CCK, COMT, F2R, GRIN2A, GRM1, IL10, NTSR1, P2RX3, PTAFR, SLC9A1, VIP |
946 | GO:2000249 | 0.01 | 3.12 | 7.48 | 13 | 20 | regulation of actin cytoskeleton reorganization | ABL1, ABL2, CSF1R, CTSV, DAPK3, PTK2B, HCK, HCLS1, NTF3, NTRK3, SEMA3E, RAPGEF3, BAIAP2 |
947 | GO:0071417 | 0.00 | 3.12 | 118.59 | 204 | 320 | cellular response to organonitrogen compound | ABL1, ADCY3, ADCY5, ADCY6, ADCY9, AHSG, AKT2, ALDOB, ANGPT1, ANXA5, APLP1, APRT, ARAF, ARG1, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, BRCA1, CALM1, CALM3, CAMK2A, CASP4, CAV2, CDC5L, CDH1, CDK2, CISH, CREB1, CSF2RB, CSH1, CTNNA1, CYP11B1, DIAPH1, DNM2, DRD5, HBEGF, DUSP5, EIF4E, EIF4EBP1, EIF4G1, ERBB2, EREG, FBN1, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FYN, GCG, GCGR, GH2, GHRHR, GHSR, GLP1R, GNAS, GNB1, GNG3, GNG10, GNG11, GNRHR, GOT1, GPLD1, FFAR3, GRB2, GRIN2A, NRG1, HIF1A, HMBS, NR4A1, HRH1, IDE, IGF1, IGF1R, IGF2, IL1B, IL2RA, INS, KIT, KRAS, MARK3, KITLG, FOXO4, YBX1, P2RY2, PEBP1, PARK2, PDE3A, PDE3B, PDE4B, PDK4, PIK3C3, PIK3CB, PPM1A, PPP5C, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCI, PRKCQ, PRKCZ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTK2, PTPN1, PTPN6, PTPRA, PTPRE, RAB13, RAF1, RANGAP1, RASA2, RHEB, RPE65, RPS6, RPS6KB1, RXRA, SRSF5, SHC1, SHMT1, SLC2A4, SLC9A1, SNCA, SOS1, SOX9, SREBF1, SSTR2, STAT1, STAT3, STAT5B, STK11, ADAM17, KLF10, TSC1, TSC2, UBB, UROS, USF1, WNT1, FGF23, CUL3, IRS4, OGT, PIK3R3, PEA15, RIPK2, KAT2B, SOCS3, ATP6V0D1, IL1RL1, ARHGEF2, KLF4, GLP2R, SLIT2, PSMF1, NRG2, ATP6V1G1, BCAR1, C2CD5, PSMD6, NR1H4, RBX1, RASA4, PSME3, PSMD14, KLF2, BAIAP2, SORBS1, SH2B2, FRS3, RAB10, RAB31, CAPN10 |
948 | GO:0006303 | 0.00 | 3.10 | 13.84 | 24 | 37 | double-strand break repair via nonhomologous end joining | ATM, BARD1, BRCA1, SETMAR, UBE2V2, SUMO1, UVRAG, WHSC1, XRCC4, XRCC5, HMGA2, HIST1H4I, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HERC2, RNF8, DCLRE1A, RAD50, PSMD14 |
949 | GO:0022408 | 0.02 | 3.09 | 6.34 | 11 | 17 | negative regulation of cell-cell adhesion | ABL1, ABL2, APOA1, CDH1, IL1RN, EPCAM, PTK2, TNR, WNT1, KLF4, MAD2L2 |
950 | GO:0007044 | 0.02 | 3.09 | 6.34 | 11 | 17 | cell-substrate junction assembly | ACTN1, BCL2, CTTN, PTK2B, ITGA5, LAMA5, TRIP6, ARHGEF7, TAOK2, SORBS1, FERMT2 |
951 | GO:0050818 | 0.00 | 3.09 | 19.07 | 33 | 51 | regulation of coagulation | ABAT, ADRB2, ALOX12, ANXA5, APOH, SERPING1, CD36, F2, F2R, F2RL1, F3, F7, FAP, FCER1G, FGA, FGG, GP1BA, FOXA2, HRG, KLKB1, KNG1, KRT1, SERPINE1, SERPINB2, PRKCD, PRKCQ, PROC, PSEN1, S100A9, SELP, USF1, VTN, PROCR |
952 | GO:0001707 | 0.02 | 3.08 | 6.35 | 11 | 17 | mesoderm formation | ACVR1, BMPR2, EPHA2, EXT2, SMAD3, PRKAR1A, SNAI1, SRF, WNT11, CHRD, HAND1 |
953 | GO:0019439 | 0.00 | 3.08 | 10.35 | 18 | 28 | aromatic compound catabolic process | AMBP, AOX1, BLVRA, BLVRB, CCBL1, COMT, CYP2A6, DBH, DIO3, GSTZ1, HAL, HNMT, IDO1, PAH, QDPR, TAT, KYNU, ALDH1L1 |
954 | GO:0000715 | 0.02 | 3.08 | 6.36 | 11 | 17 | nucleotide-excision repair, DNA damage recognition | DDB2, RAD23B, UBB, XPC, CUL4A, COPS3, COPS2, RBX1, COPS8, COPS6, COPS5 |
955 | GO:0002639 | 0.02 | 3.08 | 6.36 | 11 | 17 | positive regulation of immunoglobulin production | CD28, CD37, HPX, IFNG, IL13, XCL1, STAT6, TNFSF4, TNFRSF4, UNG, WHSC1 |
956 | GO:0003081 | 0.02 | 3.08 | 6.36 | 11 | 17 | regulation of systemic arterial blood pressure by renin-angiotensin | AGTR1, AGTR2, CTSZ, CYBA, ACE, DRD3, F2R, F2RL1, GJA5, PCSK5, ATP6AP2 |
957 | GO:0003170 | 0.02 | 3.08 | 6.36 | 11 | 17 | heart valve development | ACVR1, JAG1, PRDM1, EFNA1, ERG, GATA4, GJA5, SMAD6, SOX9, TWIST1, DCHS1 |
958 | GO:0010712 | 0.02 | 3.08 | 6.36 | 11 | 17 | regulation of collagen metabolic process | BMP4, CTGF, F2, F2R, FAP, IHH, ITGB1, CIITA, UCN, SERPINB7, RAPGEF3 |
959 | GO:0042744 | 0.02 | 3.08 | 6.36 | 11 | 17 | hydrogen peroxide catabolic process | CAT, GPX1, GPX3, HBA2, HP, PRDX1, SNCA, PXDN, EPX, PRDX6, PRDX3 |
960 | GO:0046685 | 0.02 | 3.08 | 6.36 | 11 | 17 | response to arsenic-containing substance | ALAD, ATF4, CDKN1A, CPOX, HMBS, TNFRSF11B, SERPINF1, PTEN, RBM4, UROS, GSTO1 |
961 | GO:0070741 | 0.02 | 3.08 | 6.36 | 11 | 17 | response to interleukin-6 | ALDOB, ENTPD2, FGA, GFI1, FOXA2, CITED1, PTGIS, SELPLG, STAT3, FGF23, CTR9 |
962 | GO:0071305 | 0.02 | 3.08 | 6.36 | 11 | 17 | cellular response to vitamin D | ATP2B1, BGLAP, CYP24A1, IL15, ITGB1, PENK, PIM1, PTN, FGF23, TRIM24, ADAMTS1 |
963 | GO:0072488 | 0.02 | 3.08 | 6.36 | 11 | 17 | ammonium transmembrane transport | ACACB, CPT1B, CPT2, RHAG, RHCE, RHD, SLC12A2, SLC22A1, SLC22A3, SLC22A2, SLC22A5 |
964 | GO:1901031 | 0.02 | 3.08 | 6.36 | 11 | 17 | regulation of response to reactive oxygen species | CD36, DHFR, HGF, HP, PSAP, PYCR1, SNCA, RGN, HDAC6, TRAP1, FBLN5 |
965 | GO:1903053 | 0.02 | 3.08 | 6.36 | 11 | 17 | regulation of extracellular matrix organization | ABL1, ABL2, DPP4, ETS1, FAP, FGFR4, GPX1, HSPA8, SMAD3, FSCN1, SOX9 |
966 | GO:0051251 | 0.00 | 3.07 | 16.75 | 29 | 45 | positive regulation of lymphocyte activation | AXL, CD3D, CD3G, CD5, CDC42, CTLA4, DPP4, EGR3, FLOT2, FLT3LG, FYN, GAS6, GRB2, HLA-DQA1, HLX, IHH, PRKCZ, PTPN6, RAC1, RAG1, RARA, CCL21, TRAF2, VAV1, AP3B1, TNFSF14, AP3D1, GRAP2, MALT1 |
967 | GO:0006595 | 0.00 | 3.07 | 23.19 | 40 | 62 | polyamine metabolic process | ARG1, ARG2, ASL, ASS1, CKM, CPS1, GAMT, GATM, GOT1, OAZ1, OAZ2, OTC, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, SMS, PSMF1, PSMD6, SLC25A15, PSME3, PSMD14 |
968 | GO:0045765 | 0.04 | 3.06 | 5.20 | 9 | 14 | regulation of angiogenesis | EFNA1, EPHA2, EMP2, ERBB2, KRT1, ENPP2, SP100, TNFAIP3, CXCL13 |
969 | GO:0022409 | 0.04 | 3.05 | 5.20 | 9 | 14 | positive regulation of cell-cell adhesion | FOXA2, SMAD7, RAP1GAP, CX3CL1, SOX2, PIEZO1, FSTL3, CITED2, CXCL13 |
970 | GO:0007272 | 0.00 | 3.05 | 22.07 | 38 | 59 | ensheathment of neurons | AKT2, CD9, CLU, LPAR1, EGR2, ERBB2, FGFR3, HEXB, HGF, NRG1, IFNG, ILK, KCNJ10, MAL, NTF3, PTEN, RARA, RARB, RXRA, SCN2A, SCN8A, SLC8A3, SOD1, CNTN2, TSC1, ZNF24, ATRN, CNTNAP1, EIF2B2, EIF2B5, QKI, EIF2AK3, GAL3ST1, FIG4, RNF10, TSPAN2, OLIG2, AFG3L2 |
971 | GO:0035270 | 0.04 | 3.05 | 5.20 | 9 | 14 | endocrine system development | CRKL, HHEX, HOXD3, SMAD3, RAF1, RAP1GAP, SIX1, SRF, PAX8 |
972 | GO:0071347 | 0.00 | 3.05 | 16.83 | 29 | 45 | cellular response to interleukin-1 | BYSL, HIF1A, HSPA9, ICAM1, IL1R1, IL1RN, IL17A, IRAK1, IRAK2, P2RY2, PAWR, PPP4C, PTGER4, PTGIS, UPF1, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SOX9, XCL2, VRK2, YY1, RPS6KA4, KLF2, ADAMTS7 |
973 | GO:0030799 | 0.04 | 3.05 | 5.20 | 9 | 14 | regulation of cyclic nucleotide metabolic process | PTK2B, FZD2, GUCA1A, GUCA1B, GUCA2A, GUCA2B, RCVRN, PDE5A, GUCA1C |
974 | GO:1903524 | 0.04 | 3.04 | 5.21 | 9 | 14 | positive regulation of blood circulation | ATP1A1, CTGF, EDN3, HRC, KCNQ1, PDE4D, RGS2, RYR2, TACR3 |
975 | GO:1901701 | 0.00 | 3.04 | 127.91 | 219 | 350 | cellular response to oxygen-containing compound | ADCY9, ADRA2A, AHSG, AKT2, ALDOB, ANGPT1, ANXA1, ANXA5, APRT, ARAF, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, BAD, BNIP3, CALM1, CALM3, CAMK2A, CASP4, CAV2, CDK2, AKR1C4, CISH, CSF2RB, CSH1, CYP11B1, DHFR, DPEP1, HBEGF, DUSP5, LPAR1, EFNA5, EIF4E, EIF4EBP1, EIF4G1, EPHA5, ERBB2, EREG, ERN1, ETS1, F3, FANCC, FBN1, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FYN, GATA4, GCG, GCGR, GH2, GHRHR, GHSR, GLP1R, GNG3, GNG10, GNG11, GNRHR, GOT1, GPR27, GRB2, GRIN2A, GUCY1B3, HGF, NRG1, HMGCR, NR4A1, FOXA2, IDE, IGF1R, IGF2, IL1R1, IL2RA, INS, KCNC2, KCNJ11, KIT, KRAS, MARK3, MAP3K5, KITLG, FOXO4, YBX1, OXCT1, PEBP1, PRDX1, PDE3A, PDE3B, PIK3C3, PIK3CB, PPM1A, PPP5C, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCI, PRKCQ, PRKCZ, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTK2, PTPN1, PTPN6, PTPRA, PTPRE, PTPRN, PTPRN2, PYCR1, RAB13, RAF1, RANGAP1, RASA2, RHEB, RPE65, RPS3, RPS6, RPS6KB1, RXRA, SRSF5, SHC1, SHMT1, SIPA1, SLC2A4, SLC2A5, SMARCA4, SOD2, SOS1, SRF, STAT3, STAT5B, STAT6, STK11, ADAM17, KLF10, TRAF2, TSC1, TSC2, UBB, USF1, VCAM1, WNT1, ZNF16, CUL3, IRS4, PIK3R3, PEA15, IL18RAP, KAT2B, SOCS3, RGN, ATP6V0D1, IL1RL1, ARHGEF2, HMGN3, GLP2R, SLIT2, NRXN1, PSMF1, NRG2, ATP6V1G1, BCAR1, C2CD5, C2CD2L, PSMD6, RBX1, HDAC6, IL18BP, TRAP1, RASA4, PSME3, CALCRL, PSMD14, BAIAP2, STK25, FBLN5, SORBS1, SH2B2, CERS1, GJB6, FRS3, RAB10, PRDX3, RAB31, CAPN10, ZNF277, CHEK2 |
976 | GO:0001704 | 0.00 | 3.04 | 10.44 | 18 | 28 | formation of primary germ layer | COL5A2, COL6A1, COL11A1, COL12A1, DUSP1, DUSP4, DUSP5, GATA4, GATA6, FOXA2, ITGA4, ITGA5, ITGAV, LAMA3, SOX2, VTN, FZD7, CTR9 |
977 | GO:0018958 | 0.00 | 3.04 | 10.44 | 18 | 28 | phenol-containing compound metabolic process | ASIP, ATP2B2, BCL2, CDH3, CRYM, CTNS, DIO2, DIO3, CITED1, SLC5A5, SRD5A1, STAR, TRPC1, TYR, TYRP1, PAX8, RAPGEF2, ZEB2 |
978 | GO:0001763 | 0.00 | 3.04 | 39.64 | 68 | 106 | morphogenesis of a branching structure | ACVR1, ADM, AGTR2, AREG, RERE, BAX, BCL2, PRDM1, BMP4, CAV3, CD44, CTNND2, CTSH, CTSZ, EDNRA, EPHA2, EPHA7, ESR1, ETV4, ETV5, EYA1, FGF7, B4GALT1, GPC3, GRB2, HGF, HHEX, FOXA2, HOXD11, IGF1, IHH, IL1B, IL10, ILK, KDR, KRAS, LAMA5, LLGL2, TACSTD2, CITED1, PBX1, PGR, PSPN, RXRA, SALL1, SIX1, SLC12A2, SOX2, SOX9, SOX10, SPINT1, SRF, ST14, WNT1, WNT2, WNT2B, PAX8, FZD5, TP63, DCHS1, NRP1, SOCS3, SEMA5A, SLIT2, SEMA3E, FEM1B, SPRY1, SEMA3A |
979 | GO:0007626 | 0.00 | 3.03 | 19.74 | 34 | 53 | locomotory behavior | ABAT, ADCY5, ADRA1B, ALDH1A3, APLP2, ASTN1, ATP2B2, AVP, CACNA1B, CHRNB2, CHRNB4, DBH, DRD3, ETV5, GAA, GRM1, HEXB, NRG1, HPRT1, HTR2C, IDO1, KCND2, PDE1B, PEX13, PTEN, SNAP25, SOD1, STRN, TAL1, FZD4, USP2, FIG4, RCAN2, C1QL1 |
980 | GO:0009605 | 0.00 | 3.03 | 171.00 | 294 | 485 | response to external stimulus | ABL2, ACACB, ACADS, ACTB, ACTG1, ADSL, AHCY, ALB, ALDH3A1, ALDH1A3, ALDOB, ANGPT1, APAF1, ARAF, ASCL1, ASGR1, ATF4, ATOH1, ATP2B1, BCHE, CCND1, BRCA1, BRCA2, CACNA1A, CACNB3, CAMK2A, CAT, CBS, CCNE1, CD3E, CD63, CD72, CDC42, CDKN1A, CHAT, CHN1, CLTA, CCR3, CCR8, ACKR2, COL4A3, COL4A5, COL5A2, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, COX4I1, CREB1, CRY1, CRY2, CSF1R, CSF2RB, CSNK2A1, CTSV, CYP24A1, DAD1, DCC, DCX, DDIT3, DLG3, DLX5, DNM1, DNMT3B, DPYSL3, DSC2, HBEGF, DUSP5, TYMP, EEF2, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EGR3, EPHA2, EPHA1, EPHA5, EPHA7, EPHA8, EPHB2, EPHB3, ERBB2, ERCC1, EREG, ETV4, EXT1, ACSL1, ACSL3, ACSL4, FGF3, FGF5, FGFR3, FGFR4, FLT1, FPR1, FPR3, GAST, G6PC, GCGR, GFRA1, GHRH, GLUL, CCR10, XCR1, GRB2, ARHGAP35, SERPIND1, HGF, HLCS, HMBS, HMGCL, HMGCS1, NR4A1, HRH1, HSPA8, HSP90AA1, HSP90AB1, HTR2C, INHA, ITGA1, ITGA5, ITGA9, ITGAV, KIF5A, KRAS, LDHA, ABLIM1, LIMK1, LIPC, MARK3, KITLG, MGMT, NRCAM, NRTN, NTN3, OGG1, OR1D2, OTC, OTX2, OXCT1, PEBP1, PCK1, CHMP1A, ENPP2, PFKFB1, PIK3C3, PIK3CB, PIM1, PPP5C, PRKAA1, PSPN, RELN, PSMA1, PSMA3, PSMA4, PSMA5, PSMB1, PSMB2, PSMB5, PYY, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTK2, PTN, PTPRA, PTPRJ, PTPRM, RAB13, RALA, RASA2, RBM4, RHAG, RHCE, RHD, RNASE2, RPL24, RPS6KA1, RXRA, RYK, SAA4, SATB1, SCN5A, CCL25, SDCBP, SHC1, SIAH1, SIPA1, SLC2A1, SLC16A1, SLC34A1, SLC22A3, SLIT3, SOD1, SORD, SOS1, SOS2, SRD5A1, SRF, SSTR2, STC1, SUOX, CNTN2, KLF10, TRPC1, TRPC4, TRPC5, TSC2, TSHB, TYMS, TYR, TYROBP, UBB, UPP1, VAV1, WNT11, WNT2B, ZFP36, ARHGEF5, FGF23, SOX14, CUL3, CNTNAP1, HAT1, KLF7, UNC5C, NUMB, PEA15, NRP2, ALDH1A2, ARHGEF7, KYNU, AP3D1, RPS6KA4, KALRN, USP2, AIFM1, NRXN3, LIPG, EIF2AK3, PICK1, PSMF1, ADAMTS1, NRG2, BCAR1, RAPGEF2, ATG13, ARHGEF11, FARP2, PSMD6, SETDB1, RBX1, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, PSME3, PSMD14, PEMT, VAV3, CAP1, ARPC1A, DPYSL4, GAS2L1, CXCR6, RRAGA, NRG3, CHL1, CCR9, FRS3, AFG3L2, RAB32, SLC27A4, VAX1, CORO1A |
981 | GO:0045834 | 0.00 | 3.03 | 10.45 | 18 | 28 | positive regulation of lipid metabolic process | ADRB2, AGTR1, APOH, CD81, CDC42, EEF1A2, EPHA8, PTK2B, FGFR3, FGR, FLT1, FLT3, KIT, PRKCE, PTK2, RAC1, CCL21, VAV3 |
982 | GO:0010634 | 0.00 | 3.03 | 10.45 | 18 | 28 | positive regulation of epithelial cell migration | CTSH, HBEGF, FGF7, HIF1A, IFNG, INSL3, ITGA3, JUN, ENPP2, PFN1, PRKCE, RREB1, SOX9, TAC1, VIL1, ADAM9, RAB11A, HDAC6 |
983 | GO:0010676 | 0.04 | 3.03 | 5.22 | 9 | 14 | positive regulation of cellular carbohydrate metabolic process | BAD, HRH1, NTSR1, P2RY1, PFKFB1, PFKFB2, PRKCE, PTAFR, SNCA |
984 | GO:0046427 | 0.00 | 3.03 | 15.71 | 27 | 42 | positive regulation of JAK-STAT cascade | CNTF, CSF1R, CTF1, F2R, PTK2B, FGFR3, FLT3, FYN, HCLS1, HPX, HES1, IFNA2, IFNG, IGF1, IL10, IL12B, IL13, IL15, IL18, ISL1, KIT, PTGER4, TNFRSF1A, TNFRSF18, TNFSF18, CRLF1, IL24 |
985 | GO:0032413 | 0.04 | 3.03 | 5.23 | 9 | 14 | negative regulation of ion transmembrane transporter activity | ADRA2A, CALM1, CALM3, GRK6, GSTM2, PLN, SLN, GSTO1, TRDN |
986 | GO:0032743 | 0.04 | 3.03 | 5.23 | 9 | 14 | positive regulation of interleukin-2 production | ABL1, ABL2, ANXA1, PDE4B, PDE4D, TRAF2, TNFSF4, RIPK2, MALT1 |
987 | GO:0006833 | 0.00 | 3.02 | 10.47 | 18 | 28 | water transport | ADCY3, ADCY5, ADCY6, ADCY9, AQP5, AQP6, AQP7, AVP, AVPR2, GNAS, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, UPK3A, RAB11A |
988 | GO:0051084 | 0.00 | 3.02 | 10.47 | 18 | 28 | 'de novo' posttranslational protein folding | ACTB, CCT6A, TBCB, HSPA8, PFDN1, PFDN2, TBCA, TBCD, TBCE, CCT3, TUBA4A, TUBA3C, VBP1, TUBA1A, SEP15, CCT7, CCT4, CCT2 |
989 | GO:0060711 | 0.00 | 3.02 | 10.47 | 18 | 28 | labyrinthine layer development | ADM, CDX2, CDX4, GJB5, GRB2, HES1, RBPJ, IL10, ITGA4, LLGL2, CITED1, SPINT1, ST14, VCAM1, WNT2, FZD5, SOCS3, TMED2 |
990 | GO:0065002 | 0.00 | 3.02 | 10.47 | 18 | 28 | intracellular protein transmembrane transport | AKT2, HSPA4, HSPA8, HSP90AA1, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX14, PEX19, PEX5, RTN2, PEX16, TOMM20, C2CD5, AFG3L2 |
991 | GO:0050878 | 0.00 | 3.02 | 117.55 | 200 | 317 | regulation of body fluid levels | A2M, ABL1, ACTB, ACTG1, ACTN1, ADCY3, ADCY5, ADCY6, ADCY9, ADRA2A, APLNR, ALB, ANGPT1, ANGPT2, ANXA7, APOA1, APP, ATP1B3, ATP2A1, ATP2B1, ATP2B3, AVP, AVPR2, AXL, BSG, C3, DAGLA, CALM1, CALM3, CALU, CAPZA1, CAPZB, CD9, ENTPD1, ENTPD2, CD44, CD58, CD59, CD63, CDC42, CDK2, CENPE, CLU, COL1A1, COL3A1, CSRP1, CXADR, DGKA, DGKB, DGKQ, EPHB2, F2RL2, F10, FBLN1, FGR, FLG, FLI1, FYN, GATA4, GATA6, GGCX, GNA15, GNAI1, GNAQ, GNAS, GNB1, SFN, GP9, GRB2, GRB7, GUCY1B3, HBD, HBE1, HBG1, SERPIND1, HGF, HSPB1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IGF1, IGF2, ILK, IRF1, IRF2, ITGA1, ITGA3, ITGA4, ITGA5, ITGAM, ITGAV, ITGAX, ITGB1, ITPR1, ITPR2, KIF5A, KLC1, KRAS, LAMP2, LMAN1, OLR1, P2RX1, P2RY1, SERPINA5, PDE3A, PDE3B, PDE1B, PF4, PF4V1, PFN1, PIK3CB, PRCP, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCZ, PSAP, PTK2, PTPN1, PTPN6, RAB5A, RAB27A, RAC1, RAC2, RAD51C, RAD51B, RAF1, RAP2B, SCNN1A, SCNN1B, SCNN1G, CX3CL1, SELE, SELL, SELPLG, SHC1, SLC8A3, SLC16A1, SOD1, SOS1, SPARC, SPN, SRF, STXBP1, STXBP3, TRPC3, TUBA4A, TYRO3, VAV1, VEGFB, VEGFC, WEE1, WFS1, YWHAZ, SLC7A5, AKAP1, FZD6, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, DGKZ, AP3B1, TP63, PDE5A, RAB11A, PROZ, HIST1H3F, DOK2, PAPSS2, CLDN1, FIBP, DGKI, KIF3B, BCAR1, GNA14, SH2B3, KCNMB2, ABCC4, HMG20B, RAPGEF3, VAV3, CAP1, PROCR, SH2B2, PDPN, PDE10A, KIF2C, RAPGEF4, ADAMTS13, KIF3A, SLC7A9, HPS5 |
992 | GO:1901652 | 0.02 | 3.02 | 6.89 | 12 | 19 | response to peptide | JAG1, AVPR1B, AVPR2, CASP4, IRF5, KLF10, TNFAIP3, RIPK2, IL1RL1, ARHGEF2, KLF4, KLF2 |
993 | GO:0072599 | 0.00 | 3.02 | 29.17 | 50 | 78 | establishment of protein localization to endoplasmic reticulum | FAU, RPL10A, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, RYR2, SRP9, SRP14, SRP19, SRP68, SSR1, RPL14, RPL23, RAB10, SEC61B, RPL35, SEC63 |
994 | GO:0000722 | 0.04 | 3.02 | 5.24 | 9 | 14 | telomere maintenance via recombination | FEN1, PCNA, PRIM2, RAD51, RFC3, RFC4, RFC5, RPA2, RPA3 |
995 | GO:0002089 | 0.04 | 3.02 | 5.24 | 9 | 14 | lens morphogenesis in camera-type eye | BMP4, CRYGB, EPHA2, FGFR3, SIX3, SOX1, SOX2, SOX11, BCAR3 |
996 | GO:0010259 | 0.04 | 3.02 | 5.24 | 9 | 14 | multicellular organism aging | ATM, CTSV, ERCC1, NR5A1, GHRHR, IDE, PRDM2, TP63, SEC63 |
997 | GO:0010656 | 0.04 | 3.02 | 5.24 | 9 | 14 | negative regulation of muscle cell apoptotic process | ALOX12, APOH, PTK2B, NRG1, HMGCR, IGF1, ILK, BAG3, RAPGEF3 |
998 | GO:0015874 | 0.04 | 3.02 | 5.24 | 9 | 14 | norepinephrine transport | ADRA2A, AGTR2, CRH, FFAR3, OXTR, P2RY1, PTGS1, SLC22A1, SNCA |
999 | GO:0035235 | 0.04 | 3.02 | 5.24 | 9 | 14 | ionotropic glutamate receptor signaling pathway | APP, ATP1A3, PTK2B, GRIA1, GRIA4, GRID1, GRID2, GRIK3, GRIN2A |
1000 | GO:0048255 | 0.04 | 3.02 | 5.24 | 9 | 14 | mRNA stabilization | CIRBP, DHX9, ELAVL1, HNRNPC, HNRNPD, YBX1, SLC11A1, VIP, ZFP36 |
1001 | GO:0060142 | 0.04 | 3.02 | 5.24 | 9 | 14 | regulation of syncytium formation by plasma membrane fusion | CD53, FLT3LG, STAT1, CAMK1, TNFSF14, ADAM9, CFLAR, GDF15, RAPGEF3 |
1002 | GO:0061383 | 0.04 | 3.02 | 5.24 | 9 | 14 | trabecula morphogenesis | CAV3, CHAD, COL1A1, S1PR1, NRG1, RBPJ, SRF, ADAMTS1, SEMA4D |
1003 | GO:0070897 | 0.04 | 3.02 | 5.24 | 9 | 14 | DNA-templated transcriptional preinitiation complex assembly | CREB1, PSMC1, PSMC2, PSMC3, PSMC4, TAF2, TAF7, TAF1B, IKZF1 |
1004 | GO:0071875 | 0.04 | 3.02 | 5.24 | 9 | 14 | adrenergic receptor signaling pathway | ADCY9, ADRA1B, ADRA2A, ADRB2, GNAS, PDE4D, PLN, RGS2, RAPGEF2 |
1005 | GO:1901071 | 0.04 | 3.02 | 5.24 | 9 | 14 | glucosamine-containing compound metabolic process | CHIT1, CHST6, MGAT3, OVGP1, PGM3, RENBP, OGT, GNE, CHST4 |
1006 | GO:2001267 | 0.04 | 3.02 | 5.24 | 9 | 14 | regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | BAX, SMAD3, TRAF2, TRADD, RIPK1, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR |
1007 | GO:0072522 | 0.00 | 3.02 | 53.86 | 92 | 144 | purine-containing compound biosynthetic process | ABCA1, ACACB, ADCY3, ADCY5, ADCY6, ADCY9, ADM, ADRA2A, ADRB2, ADSL, ADSS, AK1, AK2, AK4, AMPD1, AMPD2, APLP1, APRT, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, ATP5O, AVP, AVPR2, CALCR, CALM1, CALM3, CRH, DRD3, DRD5, LPAR1, EDNRA, PTK2B, FSHR, GALR1, GCG, GHRH, GHRHR, GLP1R, GNAL, GNAS, GRM8, GUCA1A, GUCA1B, GUCA2A, GUCA2B, GUCY1B3, GUCY2C, GUCY2F, GUCY2D, HPRT1, HTR2C, IMPDH1, IMPDH2, INSL3, LDHC, MAT2A, NTRK1, NTRK2, OAS2, P2RY11, PALM, PFAS, PTGER4, PTHLH, RAF1, RCVRN, SHMT1, STAT3, UCN, VIP, VIPR2, WFS1, PAPSS2, PAPSS1, AKAP6, ATP5J2, GABBR2, AKAP12, GUCA1C, SLC25A13, CALCRL, RAMP2, ATP5H, CAP1, ATP5L, SLC26A1 |
1008 | GO:1903555 | 0.00 | 3.02 | 19.82 | 34 | 53 | regulation of tumor necrosis factor superfamily cytokine production | ANGPT1, AXL, BCL3, BPI, TSPO, CD86, TNFRSF8, CD36, CLU, CYBA, FCER1G, GAS6, GHSR, HSPB1, IFNG, IL10, IL12B, ISL1, LTF, PF4, PTAFR, PTGER4, RARA, SPN, TNFAIP3, TWIST1, ZFP36, RIPK1, RIPK2, ARHGEF2, NR1H4, SPON2, GPNMB, ARFGEF2 |
1009 | GO:0043066 | 0.00 | 3.01 | 112.78 | 192 | 305 | negative regulation of apoptotic process | ABL1, ABL2, ACVR1, ADAR, ALB, ANXA1, ANXA5, ARAF, ASCL1, ATOH1, BAD, BAG1, BARD1, BCL2A1, BCL3, BDKRB2, BLK, BNIP2, BNIP3, BNIP3L, BRCA1, CAT, CBL, KRIT1, CD38, CD59, CDKN1A, CLU, COMP, CLDN7, CSF1R, CTH, CTNNA1, CTSH, CX3CR1, DAB2, DAD1, DFFA, DUSP1, EDNRA, EGR3, CTTN, ERCC5, EYA1, FGA, FGF4, FGG, FLT4, GATA6, GCG, GRINA, HCK, HSPA9, HSPB1, ICAM1, IFIT3, IGF1R, IHH, IL1A, IL1B, IL10, IL13, ING2, INS, INSL3, IRAK1, ITGAV, KCNJ1, KDR, KRT18, LTF, EPCAM, SMAD3, SMAD6, YBX1, NTSR1, OGG1, OPA1, PA2G4, PAFAH2, SERPINE1, SERPINB2, PAX4, PDE3A, PF4, SERPINB13, PIM1, PRKAA1, PRKCD, PRKCZ, MAPK8, EIF2AK2, PROC, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTPN1, RARA, RARB, RPS3A, RPS6KB1, CX3CL1, SGK1, STIL, SLC9A1, SNAI1, SON, SOX9, SOX10, STAT3, STAT5B, AURKA, SUPV3L1, TMF1, TNFAIP3, TPT1, HSP90B1, TWIST1, UBB, UCN, UNG, VDAC2, VIP, WNT1, WNT11, YWHAZ, ZNF16, PAX8, SCG2, HMGA2, CBX4, API5, TP63, BECN1, PEA15, URI1, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10D, HDAC3, TSC22D1, TAX1BP1, TNFSF18, SOCS3, SEMA5A, RGN, ARHGEF2, EIF2AK3, ATG5, PSMF1, BAG5, BAG4, RB1CC1, PSMD6, NR1H4, BCL2L10, TRAP1, PSME3, DHRS2, PSMD14, RAMP2, CITED2, ACAA2, CREB3, SEMA4D, ATG7, IVNS1ABP, ZMYND11, PROKR1, MALT1, PIM2 |
1010 | GO:0031346 | 0.00 | 3.01 | 13.36 | 23 | 36 | positive regulation of cell projection organization | BBS4, CDC42, DNM2, F2RL1, EFEMP1, KAT2A, KIT, P2RX7, ENPP2, PFN1, RAC1, RAC2, RREB1, CLRN1, VIL1, WNT1, ARHGEF7, HDAC4, ARPC2, WASF2, CDC42EP2, CDC42EP3, SEPT9 |
1011 | GO:0051952 | 0.01 | 2.99 | 9.34 | 16 | 25 | regulation of amine transport | ADRA2A, AGTR2, CACNA1A, CHRNB2, CNR1, CRH, DRD3, FFAR3, KCNA2, OXTR, P2RY1, PARK2, PCP4, PTGS1, RAB3B, SLC18A1 |
1012 | GO:2000058 | 0.00 | 2.99 | 26.93 | 46 | 72 | regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process | CAV3, CCNB1, CDC20, CDC27, CDKN2A, CLU, PTK2B, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, SKP1, SUMO3, UBB, UBE3A, WNT1, CUL1, CDC23, CDC16, PSMF1, PSMD6, PSME3, PSMD14, ANAPC10, UBE2C |
1013 | GO:0060759 | 0.00 | 2.99 | 31.04 | 53 | 83 | regulation of response to cytokine stimulus | ADAR, ANGPT1, BIRC2, BIRC3, APOA1, AXL, CHUK, CYLD, ECM1, F2RL1, GAS6, GFI1, HIF1A, UBE2K, HPX, HSP90AB1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNGR1, IL1RN, IRAK1, IRAK2, PARK2, PTPN1, PTPN6, SLIT3, STAT1, STAT2, TNFAIP3, TNFRSF1A, TRAF1, TRAF2, UBB, SUMO1, NR1H2, VRK2, PXDN, IKBKG, TRADD, RIPK1, RIPK2, TAX1BP1, CPNE1, SOCS3, KLF4, SLIT2, TRAIP, RBCK1, CDC37 |
1014 | GO:0072521 | 0.00 | 2.98 | 11.03 | 19 | 30 | purine-containing compound metabolic process | ATP2B2, CACNB4, FZD2, G6PC, OGG1, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, PF4, PDE5A, ABCG2, RAPGEF3, PDE10A |
1015 | GO:0010720 | 0.00 | 2.98 | 19.22 | 33 | 52 | positive regulation of cell development | APOA1, ATP6AP1, BAD, BAX, CDC42, COL1A1, DAB2, DNM2, FGA, FGG, B4GALT1, HOXD11, SMAD3, PDE3A, PROC, RAC1, RAC3, RFX3, RREB1, S100A10, SERPINB3, SDCBP, SNAI1, AURKA, TWIST1, PAX8, PDE5A, ARHGEF7, S1PR2, AKAP6, ARPC2, TRIB1, OLFM4 |
1016 | GO:0002223 | 0.00 | 2.97 | 29.92 | 51 | 80 | stimulatory C-type lectin receptor signaling pathway | CALM1, CALM3, CHUK, EP300, FCER1G, FYN, ICAM2, ICAM3, IL1B, ITPR1, ITPR2, KRAS, PPP3R1, PRKACB, PRKACG, PRKCD, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, RAF1, RELB, SKP1, UBB, UBE2D2, CUL1, IKBKG, UBA3, PSMF1, PSMD6, PSME3, PSMD14, MALT1 |
1017 | GO:0006413 | 0.00 | 2.97 | 28.71 | 49 | 77 | translational initiation | EIF1AX, EIF2S3, EIF4E, FAU, RPL10A, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, DENR, DDX3Y, CDC123, EIF2S2, RPL14, EIF1AY, RPL23, COPS5, RPL35 |
1018 | GO:0050821 | 0.00 | 2.97 | 25.81 | 44 | 69 | protein stabilization | APOA1, ATP1B3, CCT6A, CDKN2A, CLU, CREB1, CREBL2, EP300, FLOT2, GAPDH, GNAQ, HIST1H1B, IGF1, LAMP2, SMAD3, SMAD7, PARK2, PEX6, PFN1, PFN2, PPIB, PRKCD, PTEN, PEX19, SEL1L, STXBP1, CCT3, TSC1, SUMO1, WFS1, ZNF207, USP13, USP2, BAG3, TSPAN1, IFI30, CRTAP, CCT7, CCT4, CCT2, USP19, PIM2, CDC37, CHEK2 |
1019 | GO:0006073 | 0.00 | 2.97 | 17.58 | 30 | 47 | cellular glucan metabolic process | ADRA1B, AKT2, CALM1, CALM3, CPS1, G6PC, GAA, GCGR, GYS2, IGF1, IGF2, INS, KHK, PGM1, PHKA1, PHKA2, PHKB, PHKG1, PPP1R1A, PPP1R2, PYGB, PYGL, PYGM, UBB, UGP2, EPM2A, DYRK2, MGAM, EPM2AIP1, SORBS1 |
1020 | GO:0051437 | 0.00 | 2.97 | 21.69 | 37 | 58 | positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition | CCNB1, CDC20, CDC27, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, SKP1, UBB, CUL1, CDC23, CDC16, PSMF1, PSMD6, PSME3, PSMD14, ANAPC10, UBE2C |
1021 | GO:1902105 | 0.01 | 2.97 | 8.17 | 14 | 22 | regulation of leukocyte differentiation | APCS, BGLAP, C1QC, FSHB, FSHR, LTF, TAL1, TYROBP, CUL4A, INPP4B, GPR55, LRRC17, FSTL3, TOB2 |
1022 | GO:0007050 | 0.00 | 2.97 | 27.52 | 47 | 74 | cell cycle arrest | ABL1, AK1, BARD1, DST, CDK6, BRINP1, GADD45A, DDIT3, DHCR24, DUSP1, E4F1, EIF4G2, ERN1, GAS1, GAS2, GAS6, IFNG, IFNW1, IL12B, ILK, INHA, IRF1, SMAD3, PA2G4, PPM1A, PRKAA1, PRKAG1, RB1, RHEB, SOX2, STK11, TSC1, TSC2, TSG101, CUL4A, CUL3, CUL2, CUL1, GAS7, CDC14A, KAT2B, CDC123, GAS2L1, KHDRBS1, CGRRF1, RRAGA, WDR6 |
1023 | GO:0031099 | 0.00 | 2.96 | 16.40 | 28 | 44 | regeneration | ANXA1, BCL2, TSPO, CALU, CCNB1, CTNNA1, DHFR, ENO3, GFAP, GPX1, IFRD1, IGF1, ISL1, JUN, NTRK3, OMG, PRRX1, PRKCQ, PTEN, RXRA, SOX2, TNR, FZD7, ADAM15, CFLAR, KLF4, NREP, CHST3 |
1024 | GO:0071407 | 0.00 | 2.96 | 29.73 | 51 | 81 | cellular response to organic cyclic compound | ABCA1, ADAR, ADCY3, ADCY5, AKT2, BAD, BYSL, CASQ2, CCNB1, CDC5L, CDH1, COL1A1, CTNNA1, CYBA, DIAPH1, FGA, GNAI1, GPLD1, GSTM2, HIF1A, HMGCS1, HRH1, HSP90AB1, IFIT1, IL1B, IL18, KCNJ11, SMAD1, SMAD3, SMAD9, MGMT, NTRK1, P2RX7, P2RY1, P2RY2, P2RY6, PDE3A, RAD51, RPS6KB1, RYR1, SHMT1, SLC16A1, SLC34A1, STAT1, STAT3, TMF1, RGS20, KLF4, KEAP1, KLF2, CHEK2 |
1025 | GO:0016032 | 0.00 | 2.96 | 76.25 | 130 | 208 | viral process | AMBP, TRIM23, ARF1, BAX, BICD1, BNIP3, BNIP3L, CCNT2, CD8B, CDC25C, CENPA, AP1S1, AP2S1, CCR3, CREB1, CX3CR1, DMBT1, DYNC1I2, E4F1, EPHA2, EIF4A1, EIF4E, EIF4G1, FDPS, FYN, KAT2A, GFI1, GRB2, HCK, HPX, HSPA8, SP110, KDR, KLC1, TNPO1, IPO5, KRT18, KRT19, MAP3K5, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, RAB6A, RAC1, RALA, RANBP1, RB1, RBL1, ABCE1, SATB1, SET, SGTA, SHC1, SKP1, STAT2, STAT3, SUV39H1, TAF2, TAF4B, TAF5, TAF6, TAF10, TAF13, TBP, TSPAN7, TNFRSF1A, TOP1, TP73, TSC2, UBE3A, SUMO1, UNG, VCAM1, VIM, VRK2, EIF4H, CUL4A, CUL2, CUL1, IKBKG, CDK13, DYNLL1, EIF4G3, BECN1, RNGTT, CFLAR, KAT2B, AP1S2, AP1M1, CLDN6, PSMF1, KDM4A, CUL7, ELMO1, PSMD6, RBX1, ACOT8, ABI1, AP1M2, RAD50, ABI2, WASF2, PSME3, PSMD14, TRIM22, NXF1, CARM1, RBCK1, IVNS1ABP, ZMYND11, COPS6 |
1026 | GO:0046390 | 0.00 | 2.96 | 54.23 | 92 | 145 | ribose phosphate biosynthetic process | ABCA1, ACACB, ADCY3, ADCY5, ADCY6, ADCY9, ADM, ADRA2A, ADRB2, ADSL, ADSS, AK1, AK2, AK4, AMPD1, AMPD2, APLP1, APRT, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, ATP5O, AVP, AVPR2, CALCR, CALM1, CALM3, CRH, CTPS1, DRD3, DRD5, LPAR1, EDNRA, PTK2B, FSHR, GALR1, GCG, GHRH, GHRHR, GLP1R, GNAL, GNAS, GRM8, GUCA1A, GUCA1B, GUCA2A, GUCA2B, GUCY1B3, GUCY2C, GUCY2F, GUCY2D, HPRT1, HTR2C, IMPDH1, IMPDH2, INSL3, LDHC, NTRK1, NTRK2, P2RY11, PALM, PFAS, PTGER4, PTHLH, PYGL, RAF1, RCVRN, STAT3, UCN, UPP1, VIP, VIPR2, WFS1, PAPSS2, PAPSS1, AKAP6, ATP5J2, GABBR2, AKAP12, GUCA1C, SLC25A13, CALCRL, RAMP2, ATP5H, CAP1, ATP5L, SLC26A1 |
1027 | GO:0043149 | 0.01 | 2.95 | 8.21 | 14 | 22 | stress fiber assembly | ARHGAP6, BBS4, S1PR1, PTK2B, TACSTD2, PFN1, PTGER4, SLC9A1, SRF, TSC1, ALMS1, CUL3, WASF2, SORBS1 |
1028 | GO:0001836 | 0.01 | 2.94 | 8.22 | 14 | 22 | release of cytochrome c from mitochondria | BAD, BAX, BCL2, BCL2A1, BID, BNIP3, CCK, CLU, SFN, JUN, SOD2, HRK, TNFSF10, BCL2L11 |
1029 | GO:0032945 | 0.00 | 2.94 | 12.34 | 21 | 33 | negative regulation of mononuclear cell proliferation | ATM, PRDM1, BMP4, CBLB, CDKN2A, CTLA4, ERBB2, IHH, IL2RA, IL10, IDO1, PAWR, PRKAR1A, PTPN6, XCL1, SFTPD, SOX11, SPN, SCGB1A1, PDE5A, GLMN |
1030 | GO:0006367 | 0.00 | 2.94 | 44.83 | 76 | 120 | transcription initiation from RNA polymerase II promoter | NR0B1, RUNX2, CCNC, CCNH, CCNT1, CCNT2, CDK8, CDK9, COX4I1, COX5B, COX6A1, COX6B1, COX7C, COX8A, CTGF, E2F2, E2F4, ERCC3, ESR1, ESRRG, NR5A2, NR5A1, NR6A1, GLS, SFN, GPX2, GTF2F1, GTF2I, NR4A1, HNF4G, RBPJ, SMAD3, SMAD7, MAZ, PRDX1, SERPINE1, PGR, PPM1A, PRKAA1, PRKAG1, RARA, RARB, RBL1, RHEB, RXRA, RXRG, SP1, TAF2, TAF4B, TAF5, TAF6, TAF7, TAF10, TAF13, TBP, NR2F1, NR2C1, NR2C2, TSC1, TSC2, UBB, NR1H2, YWHAZ, ZNF45, USP9X, TP63, KAT2B, COX7A2L, MAML1, NR1I3, NR1H4, NR1D2, NR2E3, RRAGA, YWHAQ, GTF2A1L |
1031 | GO:0051272 | 0.00 | 2.94 | 89.01 | 150 | 238 | positive regulation of cellular component movement | AAMP, ACVR1, ADAM10, ADRA2A, AKT2, ALOX12, ANGPT1, ANXA3, BCL2, BMP4, BMPR2, CGA, COL1A1, CLDN7, CSF1R, CTSH, DAB2, DAPK3, DIAPH1, HBEGF, S1PR1, LPAR1, EDN3, EDNRA, EPHA1, ETS1, F2R, F2RL1, F3, F7, F10, PTK2B, FBLN1, FGF7, FGR, FLT1, FLT4, FSHB, GAS6, GPLD1, GRB7, CXCL1, CXCL3, HGF, HIF1A, ONECUT1, HSPB1, ICAM1, IFNG, IGF1, IGF1R, IL1B, ILK, INS, INSL3, ITGA3, ITGA4, ITGA5, ITGAV, ITGB1, JUN, KDR, KIT, EPCAM, SMAD3, KITLG, NTF3, NTRK3, P2RY2, P2RY6, SERPINE1, PAWR, ENPP2, PF4, PF4V1, PFN1, PRKCE, PRKD1, RELN, PTAFR, PTGER4, PTK2, RAC1, RAC2, RDX, RPS6KB1, RPS19, RREB1, S100A7, SERPINB3, CCL20, CCL21, CCL24, CXCL6, CXCL5, XCL1, CX3CL1, SDCBP, SELE, SELP, SEMA3F, SNAI1, SOX9, SPARC, STAT5B, TAC1, ADAM17, TRIP6, TWIST1, VEGFB, VEGFC, VIL1, VTN, WNT11, SEMA3B, MADCAM1, IKBKAP, NUMB, TNFSF14, ADAM9, RAB11A, TNFRSF18, NRP2, NRP1, ARHGEF7, TNFSF18, SEMA5A, ITGB1BP1, CHST3, ONECUT2, BAG4, CXCL14, BCAR1, RAPGEF2, SEMA3E, HDAC4, HDAC6, PDCD6, SEMA3A, ATP8A1, RAPGEF3, CREB3, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, CXCL13, PDPN, CORO1A |
1032 | GO:0071156 | 0.00 | 2.94 | 23.54 | 40 | 63 | regulation of cell cycle arrest | AKT2, ATM, BRCA1, CDK2, CDKN1A, CDKN2A, FAP, GATA6, FOXO4, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, TP73, UBB, RNF112, HMGA2, CRADD, PSMF1, PSMD6, PSME3, PSMD14 |
1033 | GO:0003254 | 0.01 | 2.94 | 8.23 | 14 | 22 | regulation of membrane depolarization | ALOX12, BCL2, TSPO, CAV3, CCK, DCN, GJA5, KDR, SMAD7, NTSR1, P2RX7, SCN5A, SCN10A, HCN4 |
1034 | GO:0018149 | 0.01 | 2.94 | 8.23 | 14 | 22 | peptide cross-linking | ANXA1, COL3A1, DCN, DSP, EVPL, SPRR1B, SPRR2A, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3, SPOCK2, ABCA7 |
1035 | GO:0043524 | 0.00 | 2.92 | 26.55 | 45 | 71 | negative regulation of neuron apoptotic process | AARS, ANGPT1, AXL, BAX, BCL2, BCL2L1, CACNA1A, CNTF, F2R, PTK2B, FYN, GABRA5, HIF1A, HSP90AB1, ILK, ISL1, JUN, KRAS, CITED1, NTF3, NTF4, NTRK1, NTRK2, PARK2, PCP4, PRKCI, PSEN1, SET, SIX1, SNCB, SNCA, SOD1, SOD2, STAR, STXBP1, TP73, TYRO3, VEGFB, WFS1, XRCC2, NRP1, CRLF1, STAMBP, CHL1, CORO1A |
1036 | GO:0006873 | 0.00 | 2.92 | 110.33 | 185 | 295 | cellular ion homeostasis | ABCB7, ABL1, ABL2, ACO1, ADCY5, ADM, ADRA1B, AGTR1, AGTR2, ALAS2, ANXA6, ANXA7, APLP2, APP, ARF1, ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP1A4, ATP1B3, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP4A, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, ATP7B, AVP, AVPR1B, BAX, BCL2, BDKRB2, BMP4, BMP6, CA2, CACNA1A, CACNB4, CALCR, CALM1, CALM3, CASQ1, CASQ2, CAV3, CD4, CD36, CD38, CD52, CFTR, CLCN3, CLN5, CCR3, CCR5, CCR8, CYBA, DDIT3, DIAPH1, DRD3, DRD5, S1PR1, LPAR1, S1PR3, EDN3, EDNRA, ESR1, F2, F2R, F2RL1, PTK2B, FTL, GALR1, GLP1R, GNA15, GNAT2, GNB1, GNG3, CCR10, XCR1, UTS2R, GRINA, GRM1, GSTM2, GTF2I, HEXB, HIF1A, HPX, HRC, HTR2C, IL1B, IL13, ITGB1, ITPR1, ITPR2, KCNJ2, KCNK3, KISS1, KNG1, LTF, NUBP1, SLC11A2, NTSR1, OXTR, P2RX3, P2RX4, P2RX5, P2RX7, P2RY1, P2RY2, P2RY4, PDE4D, PIK3CB, PLN, PRKCE, PRKD1, PSEN1, PTPN6, PYGM, RAP1GDS1, RHAG, RYR1, RYR2, RYR3, S100A8, S100A9, SCO1, CCL21, XCL1, SGK1, SLC4A1, SLC8A3, SLC9A1, SLC11A1, SNCA, SOD1, STC1, TAC1, TNNI3, TPT1, HSP90B1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, TRPV1, WFS1, SLC30A2, SLC30A3, SLC30A4, RAB7A, CSRP3, FGF23, S1PR4, INPP4B, AP3D1, TRPA1, RGN, ATP6V0D1, SLC24A1, VAPB, SLC9A3R1, ABCG2, GSTO1, AKAP6, ATG5, ATP6V1G1, HEPH, ABCB6, SGK2, TRDN, CIB2, CHERP, CXCL13, SLC34A2, SCGN, CCR9, SLC26A1, IMMT, CORO1A |
1037 | GO:0045862 | 0.00 | 2.91 | 37.17 | 63 | 100 | positive regulation of proteolysis | ADRA2A, ALOX12, APAF1, APP, BAD, BAX, BID, BOK, C3, CASP1, CASP9, CCK, CDKN2A, COL4A3, CTGF, CTSH, F2R, F3, FBLN1, FGFR4, GPLD1, HIP1, IFI16, IFNG, IL1B, KLKB1, SMAD3, MAP3K5, SLC11A2, P2RX1, PAWR, PCOLCE, REST, RPS3, S100A8, S100A9, SERPINB3, SEMG1, SNCA, CNTN2, CLEC3B, TNFRSF1B, TRAF2, PICALM, OGT, TRADD, RIPK1, CRADD, TNFSF10, ADAM9, TNFRSF10B, TNFRSF10A, CFLAR, AIFM1, EIF2AK3, IST1, TNFSF15, CASP8AP2, PDCD6, BCL2L10, BCL2L11, ARL6IP5, ADRM1 |
1038 | GO:0071333 | 0.00 | 2.91 | 11.19 | 19 | 30 | cellular response to glucose stimulus | CYBA, ERN1, GAS6, GATA4, GHRHR, ICAM1, IGF1, IGF1R, IL1B, IL1R1, KCNJ11, SERPINF1, PTGER4, SMARCA4, SRF, STAR, VCAM1, OGT, GJB6 |
1039 | GO:0071248 | 0.00 | 2.91 | 18.28 | 31 | 49 | cellular response to metal ion | ATF4, BMP6, BNIP3, CCNB1, CD86, CDH1, CRHBP, CYP11B1, DPEP1, EIF2S1, GPLD1, GUCA1A, HIF1A, JUN, JUND, KCNA1, KCNJ1, PARK2, SERPINF1, RYR3, SCN5A, SLC34A1, SLC18A1, SNCA, SYT1, XRCC4, BECN1, CPNE1, EIF2AK3, RASA4, FSTL3 |
1040 | GO:0009314 | 0.00 | 2.91 | 27.63 | 47 | 75 | response to radiation | ALAD, ANGPT2, ANXA1, ATM, BCL2L1, BRCA1, COL3A1, CYBA, GADD45A, DNMT1, DNMT3B, EYA1, EYA3, FANCD2, FANCG, GRB2, ICAM1, IFI16, IGF2, IL1B, IL1R1, JUN, KRT13, MGMT, NTRK1, PENK, PGM1, RAD1, RAD51, RAD51C, RAD51B, RAD51D, RRM1, STAR, VCAM1, XRCC2, XRCC4, XRCC5, HMGA2, SMC1A, PPM1D, MBD4, SOCS3, RNF8, TRIM13, RAD51AP1, CHEK2 |
1041 | GO:0018130 | 0.00 | 2.90 | 11.47 | 20 | 33 | heterocycle biosynthetic process | ALAD, ALAS1, ALAS2, TSPO, COX15, CPOX, CPS1, HMBS, IDO1, SLC11A2, OAT, PYCR1, ALDH18A1, QDPR, UROS, PDXK, ALDH4A1, SUCLA2, ABCB6, PRG3 |
1042 | GO:0050772 | 0.00 | 2.90 | 11.22 | 19 | 30 | positive regulation of axonogenesis | BMPR2, EFNA5, GOLGA4, NRG1, ILK, LIMK1, NTRK2, NTRK3, SRF, CDKL5, STK11, RND2, RAB11A, NRP1, SEMA5A, SLIT2, IST1, STK25, SEMA4D |
1043 | GO:1903146 | 0.00 | 2.90 | 11.22 | 19 | 30 | regulation of mitophagy | ACTL6A, ADRB2, BNIP3L, TSPO, CSNK2A2, CTSK, CTTN, KAT2A, HIF1A, PARK2, SREBF1, U2AF1, ZBTB17, FZD5, RUVBL1, BECN1, ATG5, HDAC6, ATG7 |
1044 | GO:0042552 | 0.00 | 2.89 | 14.18 | 24 | 38 | myelination | AKT2, CD9, LPAR1, EGR2, ERBB2, HEXB, ILK, MAL, NTF3, SCN2A, SCN8A, SLC8A3, SOD1, TSC1, ZNF24, ATRN, CNTNAP1, EIF2B2, EIF2B5, QKI, GAL3ST1, TSPAN2, OLIG2, AFG3L2 |
1045 | GO:0051341 | 0.02 | 2.89 | 7.09 | 12 | 19 | regulation of oxidoreductase activity | ACVR2A, CAV3, CNR1, CNR2, DNM2, DRD5, GFI1, HP, HSP90AA1, IL13, PARK2, HDAC6 |
1046 | GO:0031644 | 0.02 | 2.89 | 7.09 | 12 | 19 | regulation of neurological system process | ACPP, ADRB2, CCK, COMT, F2R, GRIN2A, GRM1, HTR2C, IL10, NTSR1, SLC9A1, VIP |
1047 | GO:0040014 | 0.02 | 2.88 | 7.09 | 12 | 19 | regulation of multicellular organism growth | ADRB2, APP, DRD3, GAMT, GNAS, IGF1, SOD1, STAT3, ATRN, HDAC3, RAI1, AFG3L2 |
1048 | GO:1904063 | 0.02 | 2.88 | 7.09 | 12 | 19 | negative regulation of cation transmembrane transport | CAV3, DRD3, KCNE1, KCNH2, KCNQ1, PRKCE, SUMO1, KCNAB1, SLC9A3R1, OXSR1, KCNE2, KCNE3 |
1049 | GO:0001895 | 0.00 | 2.88 | 14.21 | 24 | 38 | retina homeostasis | ABCA4, ACTB, ACTG1, ALB, AZGP1, BBS1, BBS2, BBS4, CDH3, CLCN3, ERCC6, HSPB1, KRT1, LTF, PRDX1, PIGR, RPE65, SOD1, TUB, TULP1, USH2A, CLRN1, CROCC, CIB2 |
1050 | GO:0048015 | 0.00 | 2.88 | 43.38 | 73 | 116 | phosphatidylinositol-mediated signaling | ANGPT1, BAD, CASP9, CAT, CBL, CD28, CD80, CD86, CDKN1A, CHUK, CREB1, CRYBA1, CSF1R, DCN, HBEGF, ERBB2, EREG, F2, F2R, F2RL1, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FGR, FLT1, FLT3, FSHR, FYN, GRB2, HCLS1, HGF, NRG1, NR4A1, IGF1, IGF1R, INS, KDR, KIT, KITLG, FOXO4, NTRK1, NTRK2, PIK3C2B, PIK3C3, PIK3CB, PI4KA, RELN, PTAFR, PTEN, PTK2, PTPN6, PTPN13, RPS6KB1, RPS6KB2, SELP, SOX9, TSC2, TWIST1, TYRO3, UBE3A, VAV1, FGF23, OGT, BECN1, KLF4, SLC9A3R1, NRG2, GAB2, SEMA4D, STAMBP |
1051 | GO:0002791 | 0.00 | 2.88 | 49.37 | 83 | 132 | regulation of peptide secretion | ABAT, ADCY5, ADRA2A, ANXA5, ARL2, ARNTL, BAD, BLK, CACNA1A, CD38, CFTR, CHRM3, CNR1, CRH, CRHBP, EFNA5, EPHA5, FGA, FGG, GCG, GHRH, GHRHR, GHSR, GLP1R, GLUD1, GLUL, GNAS, GPLD1, GPR27, FFAR1, FFAR3, HIF1A, HMGCR, FOXA2, HTR2C, IFNG, IL1B, INS, ISL1, ITPR1, ITPR2, KCNC2, KCNJ11, KCNS3, KISS1, OXCT1, PARK2, PDE3B, PDE4C, PFKFB2, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PTGER4, REST, RFX3, S100A8, S100A9, SLC2A1, SLC16A1, SNAP25, SREBF1, STXBP1, ABCC8, SYT5, TRPM2, UCN, PAX8, ARHGEF7, SYT7, HMGN3, NRXN1, STXBP5L, CLOCK, C2CD2L, NR1H4, RAPGEF3, RAPGEF4, CAPN10 |
1052 | GO:0015909 | 0.02 | 2.88 | 7.10 | 12 | 19 | long-chain fatty acid transport | ACACB, AKT2, ABCD1, ANXA1, BDKRB2, CPT1B, CPT2, ACE, DRD3, NTSR1, ABCD3, SLC27A5 |
1053 | GO:0002762 | 0.02 | 2.88 | 7.11 | 12 | 19 | negative regulation of myeloid leukocyte differentiation | APCS, C1QC, INHA, LTF, RARA, CUL4A, INPP4B, GPR55, TRIB1, LRRC17, FSTL3, TOB2 |
1054 | GO:0015985 | 0.02 | 2.88 | 7.11 | 12 | 19 | energy coupled proton transport, down electrochemical gradient | ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, ATP5O, ATP5J2, ATP5H, ATP5L |
1055 | GO:0032722 | 0.02 | 2.88 | 7.11 | 12 | 19 | positive regulation of chemokine production | ALOX15B, CSF1R, FFAR3, HIF1A, IFNG, IL1B, P2RY2, EIF2AK2, ADAM17, TWIST1, RIPK2, IL1RL1 |
1056 | GO:0033598 | 0.02 | 2.88 | 7.11 | 12 | 19 | mammary gland epithelial cell proliferation | AREG, BAX, CCND1, BRCA2, CHUK, EPHA2, ESR1, ETV4, GPX1, RREB1, STAT6, DEAF1 |
1057 | GO:0042491 | 0.02 | 2.88 | 7.11 | 12 | 19 | auditory receptor cell differentiation | JAG1, ATOH1, ATP2B2, GFI1, HES1, RBPJ, RAC1, SOD1, CLRN1, SLC9A3R1, SLC4A7, SEC24B |
1058 | GO:0048873 | 0.02 | 2.88 | 7.11 | 12 | 19 | homeostasis of number of cells within a tissue | ADD1, BAX, BCL2, CD7, F2R, FLT3, KRAS, P2RX7, RAC1, RAC3, SOX9, CORO1A |
1059 | GO:0055010 | 0.02 | 2.88 | 7.11 | 12 | 19 | ventricular cardiac muscle tissue morphogenesis | COL11A1, DSP, NRG1, RBPJ, ISL1, SMAD7, RXRA, RYR2, TNNC1, TNNI3, TNNT2, HAND1 |
1060 | GO:0097306 | 0.01 | 2.88 | 10.05 | 17 | 27 | cellular response to alcohol | ABCA1, BRCA1, KLF9, CDH1, CTNNA1, ELK1, GLRA1, GLRA2, GPLD1, HMGCS1, ITPR2, PRKAA1, PRKCE, PTAFR, RAD51, KLF4, KLF2 |
1061 | GO:0033077 | 0.01 | 2.86 | 10.08 | 17 | 27 | T cell differentiation in thymus | BCL2, ZFP36L2, CD3D, CD3E, CD28, CDK6, RAG1, RAG2, SPN, SRF, STAT5B, STK11, ADAM17, WNT1, FZD5, FZD7, FZD8 |
1062 | GO:0007270 | 0.00 | 2.86 | 13.05 | 22 | 35 | neuron-neuron synaptic transmission | CA2, CAMK4, CHRNB2, CNR2, CRH, CRHBP, DNM1, DRD3, DRD5, GLRA1, GLRA2, KRAS, PRKCE, PTEN, RAB3B, RAC1, RAC3, SNCA, STXBP1, TAC1, SYN3, SLC6A5 |
1063 | GO:0010812 | 0.01 | 2.85 | 10.10 | 17 | 27 | negative regulation of cell-substrate adhesion | ACVRL1, ANGPT2, ARHGAP6, CDKN2A, COL1A1, FBLN1, TACSTD2, SERPINE1, PTEN, SPOCK1, TBCD, WNT1, FZD4, FZD7, ADAM15, ITGB1BP1, SEMA3E |
1064 | GO:0042130 | 0.01 | 2.85 | 10.10 | 17 | 27 | negative regulation of T cell proliferation | BMP4, CBLB, CDKN2A, ERBB2, IHH, IL2RA, IL10, IDO1, PAWR, PRKAR1A, PTPN6, XCL1, SFTPD, SPN, SCGB1A1, PDE5A, GLMN |
1065 | GO:0055081 | 0.01 | 2.85 | 10.10 | 17 | 27 | anion homeostasis | ABCA1, APOA1, CACNA1A, CPS1, FGFR4, GOT1, INS, OTC, PRKAA1, SFRP4, SLC34A1, FGF23, DGAT1, SLC9A3R1, LIPG, ABCG1, SLC34A2 |
1066 | GO:0032845 | 0.00 | 2.84 | 33.98 | 57 | 91 | negative regulation of homeostatic process | ABL1, ADRA2A, ATM, ATP1A2, AVPR2, BAX, CASQ1, CD38, CCR5, COMT, CYBA, DDIT3, DIAPH1, TSC22D3, EDNRA, ERCC1, ERCC4, F2, F2R, PTK2B, FCER1G, XCR1, UTS2R, HMGCR, HNRNPC, HRC, HTR2C, IAPP, IL13, ITPR1, ITPR2, KITLG, TNFRSF11B, P2RX7, PDE4D, PLN, PRKCE, PRKD1, PTPN6, RYR1, RYR2, RYR3, CCL21, XCL1, SNCA, STAT5B, TNFAIP3, TRPC1, TRPV1, XRCC5, TRPA1, AKAP6, ATG5, RAD50, CHERP, GAS2L1, CORO1A |
1067 | GO:0021675 | 0.00 | 2.84 | 16.08 | 27 | 43 | nerve development | PHOX2A, CHRNB2, CTSV, LPAR1, EGR2, FGFR3, GABRA5, HOXD3, HES1, ILK, ISL1, KCNA2, NRTN, NTF3, NTF4, NTRK1, ATP8B1, RPL24, SALL1, SEMA3F, SIX1, SLC1A3, NRP2, NRP1, PHOX2B, SEMA3A, AFG3L2 |
1068 | GO:0001501 | 0.00 | 2.84 | 25.56 | 43 | 69 | skeletal system development | ACVR2A, AEBP1, AHSG, ARSE, COL3A1, COL5A2, COL9A2, COL12A1, VCAN, DLX6, EPHA2, EN1, EXT1, EXTL1, FBN1, GJA5, GNAQ, HEXB, HOXC10, HOXD12, IGF2, INHA, MATN3, TNFRSF11B, PRDX1, PBX1, PCSK5, PHEX, RPL38, TRAPPC2, SP1, KLF10, CLEC3B, TP63, CHRD, DLK1, PAPSS1, ADAMTS4, HDAC4, DEAF1, DMRT2, EBP, RAI1 |
1069 | GO:0071326 | 0.00 | 2.83 | 25.06 | 42 | 67 | cellular response to monosaccharide stimulus | ADCY5, ADRA2A, BAD, CFTR, CRH, CYBA, EFNA5, EPHA5, ERN1, GAS6, GATA4, GCG, GHRHR, GPLD1, GPR27, HIF1A, HMGCR, FOXA2, ICAM1, IGF1, IGF1R, IL1B, IL1R1, KCNJ11, OXCT1, SERPINF1, PRKCE, PTGER4, PTPRN, PTPRN2, RAF1, SLC2A5, SMARCA4, SRF, STAR, VCAM1, OGT, HMGN3, NRXN1, C2CD2L, NR1H4, GJB6 |
1070 | GO:0019932 | 0.00 | 2.83 | 14.86 | 25 | 40 | second-messenger-mediated signaling | ADCY3, ADCY5, ADCY6, ADCY9, ADM, DGKQ, EPHA5, GHRH, GHRHR, GLP1R, GNAI1, GNAS, PDE3A, PDE3B, PDE4A, PDE7A, PF4, PPP2R1A, RGS2, SOX9, RAPGEF2, RIMS2, RAPGEF3, PDE10A, RAPGEF4 |
1071 | GO:0044033 | 0.00 | 2.83 | 44.88 | 75 | 120 | multi-organism metabolic process | CCNH, CCNT1, CDK9, CHD1, EP300, ERCC3, FAU, GTF2F1, JUN, RPL10A, NUP88, NUP98, RANBP2, REST, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, SMARCA4, SP1, SP100, TRIM21, SSRP1, SUPT4H1, TOP2A, TSG101, UBB, USF1, NUP214, AAAS, HMGA2, RPL14, CTDP1, RPL23, ATG5, NUP155, NUP93, TRIM13, IFITM3, ATG7, NUP50, NUPL2, SUPT16H, RPL35 |
1072 | GO:0051336 | 0.00 | 2.83 | 12.39 | 21 | 34 | regulation of hydrolase activity | EFNA5, EPHA5, EPHA7, EPHB3, MGMT, NTRK2, OAS3, PSMA3, PTK2, SLN, SNRNP70, SOD1, SOX2, DYNLT1, TNNC1, TPM2, TP63, CCPG1, ITGB1BP1, KIAA0141, BVES |
1073 | GO:2000377 | 0.00 | 2.83 | 11.89 | 20 | 32 | regulation of reactive oxygen species metabolic process | BIRC2, BCL2, BNIP3, BRCA1, HIF1A, HP, IGF1, IL10, PARK2, PRCP, PTGER4, PTGIS, RAC1, RAC2, STAT3, BECN1, STK17A, ATG5, HDAC6, TRAP1 |
1074 | GO:0009190 | 0.00 | 2.83 | 11.89 | 20 | 32 | cyclic nucleotide biosynthetic process | ADCY3, ADCY5, ADCY6, ADCY9, ADRA2A, AMPD2, APLP1, DRD3, LPAR1, PTK2B, GALR1, GRM8, GUCY1B3, GUCY2C, GUCY2F, GUCY2D, HTR2C, PALM, AKAP6, GABBR2 |
1075 | GO:0048871 | 0.00 | 2.83 | 19.61 | 33 | 53 | multicellular organismal homeostasis | ACACB, ADCY3, ADCY5, ADCY6, ADCY9, ALOX12, AMPD2, AVP, AVPR2, BMP6, CD36, FLG, SFN, SLC11A2, PRCP, PRKAA1, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, RHAG, SCNN1A, SCNN1B, SCNN1G, SLC11A1, UBB, WFS1, TP63, RAB11A, CLDN1, NR1D2 |
1076 | GO:0008217 | 0.00 | 2.83 | 23.85 | 40 | 64 | regulation of blood pressure | ACVRL1, ADH5, ADRA1B, AGTR1, ATP1A1, ATP1A2, AVP, AVPR1B, AVPR2, CACNA1B, CTSZ, CYBA, CYP11B1, ACE, EDN3, EDNRA, EMP2, F2R, F2RL1, GAS6, GCGR, GLP1R, NRG1, OXTR, P2RX1, P2RX4, PCSK5, PDE4D, PTGS1, RENBP, ACSM3, SGK1, SLC2A5, SOD1, TAC1, TACR3, TNNI3, ATP6AP2, RAMP2, CORIN |
1077 | GO:0060541 | 0.04 | 2.82 | 5.95 | 10 | 16 | respiratory system development | ALDH1A3, ASS1, DLX5, EDA, RARA, SIX1, KCNAB1, HESX1, PHOX2B, SPEG |
1078 | GO:0009749 | 0.00 | 2.82 | 11.91 | 20 | 32 | response to glucose | ACVR2B, ANGPT2, COL6A2, CTGF, CTSV, EIF2B1, PTK2B, GLUL, GYS2, KHK, LDHA, PFKFB2, PRKCQ, PTEN, RPS6KB1, SREBF1, EIF2B3, EIF2B2, EIF2B5, TXNIP |
1079 | GO:0048839 | 0.00 | 2.82 | 14.91 | 25 | 40 | inner ear development | JAG1, BMP4, C1QB, DFNA5, FGFR3, GABRA5, HES1, IGF1, RBPJ, KCNK2, KCNK3, KCNQ1, NTRK3, ATP8B1, SDC4, SPARC, USH2A, DCHS1, LIN7A, PHOX2B, SLC9A3R2, ATG5, SLC4A7, CXCL14, GJB6 |
1080 | GO:0009914 | 0.00 | 2.81 | 69.19 | 115 | 185 | hormone transport | ABAT, ACVR2B, ADCY5, ADM, ADRA2A, AGTR1, AGTR2, ANXA1, ANXA5, ARL2, ARNTL, BAD, BLK, BMP6, CACNA1A, CD38, CFTR, CHRM3, CNR1, CREB1, CRH, CRHBP, CRY1, CRYM, EDN3, EFNA5, EPHA5, FGA, FGG, GALR1, GCG, GDF9, GHRH, GHRHR, GHSR, GLP1R, GLUD1, GLUL, GNAS, GPLD1, GPR27, FFAR1, FFAR3, HIF1A, HMGCR, FOXA2, HTR2C, IFNG, IL1B, IL1RN, INHA, INS, ISL1, ITPR1, ITPR2, KCNC2, KCNJ11, KCNS3, KISS1, OXCT1, P2RY1, PARK2, PDE3B, PDE4C, PFKFB2, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PTGER4, PTGS1, PTPRN, PTPRN2, RAB1A, RAF1, REST, RFX3, SLC2A1, SLC16A1, SLC22A1, SNAP25, SOX11, SREBF1, STXBP1, STXBP3, ABCC8, SYT5, TAC1, SERPINA7, HNF1A, TMF1, TRPM2, UCN, VIP, PAX8, FGF23, FZD4, VAMP8, ARHGEF7, SYT7, HMGN3, NRXN1, EIF2AK3, STXBP5L, CLOCK, RIMS2, C2CD2L, NR1H4, RAPGEF3, CPLX1, RAPGEF4, CAPN10 |
1081 | GO:0003206 | 0.01 | 2.81 | 8.96 | 15 | 24 | cardiac chamber morphogenesis | CAV3, COL11A1, DSP, NRG1, HIF1A, RBPJ, RXRA, RYR2, SMARCD3, SRF, TNNC1, TNNI3, TNNT2, WNT2, ADAMTS1 |
1082 | GO:0048640 | 0.01 | 2.80 | 8.96 | 15 | 24 | negative regulation of developmental growth | ADRB2, BBS2, BMP4, CAV3, CXADR, DCC, EPHA7, FGFR3, GNAS, KCNK2, PTEN, PTK2, TP73, CTDP1, RAI1 |
1083 | GO:0042490 | 0.00 | 2.80 | 14.96 | 25 | 40 | mechanoreceptor differentiation | JAG1, ATOH1, ATP2B2, BMP4, DFNA5, FGFR3, FZD2, GABRA5, GFI1, HES1, RBPJ, NTF3, NTF4, NTRK1, NTRK2, NTRK3, ATP8B1, RAC1, SDC4, SOD1, USH2A, CLRN1, SLC9A3R1, SLC4A7, SEC24B |
1084 | GO:0060840 | 0.00 | 2.80 | 14.96 | 25 | 40 | artery development | ACVR2B, ACVRL1, JAG1, PRDM1, BMP4, BMPR2, COL3A1, DNM2, EYA1, GJA5, HPGD, HES1, RBPJ, LTBP1, SMAD6, SMAD7, PRRX1, PTGER4, SIX1, SRF, WNT11, NRP1, SNX17, RAPGEF3, SEC24B |
1085 | GO:0042593 | 0.00 | 2.80 | 42.64 | 71 | 114 | glucose homeostasis | ADCY5, ADRA1B, ADRA2A, BAD, CAV3, CFTR, CNR1, CRH, CRY1, CRY2, CYBA, CYP11B1, DBH, EFNA5, EPHA5, ERN1, FGFR4, G6PC, SLC37A4, GAS6, GATA4, GCG, GCGR, GHRHR, GPLD1, GPR27, FFAR1, HIF1A, HMGCR, FOXA2, ICAM1, IGF1, IGF1R, IGFBP5, IL1B, IL1R1, INS, KCNJ11, OXCT1, PCK1, PDE3B, PDK4, SERPINF1, PRCP, PRKAA1, PRKCE, PTGER4, PTPRN, PTPRN2, PYGL, RAF1, RANBP2, RPS6, SLC2A4, SLC16A1, SMARCA4, SRF, STAR, STAT3, STK11, HNF1A, USF1, VCAM1, WFS1, OGT, HMGN3, NRXN1, STXBP5L, C2CD2L, NR1H4, GJB6 |
1086 | GO:0019748 | 0.00 | 2.80 | 11.97 | 20 | 32 | secondary metabolic process | ARL1, ASIP, BCL2, CDH3, AKR1C4, CTNS, CYP2A6, CYP11B1, IL1B, CITED1, PAM, PGAM1, PGAM2, STAR, TRPC1, TYR, TYRP1, AKR1C3, RAPGEF2, ZEB2 |
1087 | GO:0048538 | 0.00 | 2.80 | 11.97 | 20 | 32 | thymus development | ABL1, BCL2, CACNB4, CRKL, EPHB3, FGF3, HES1, JARID2, PBX1, PSEN1, RAF1, RAG1, SIX1, SOD1, SRF, TYR, FOXN1, CCNB2, BCL2L11, IKZF1 |
1088 | GO:0008206 | 0.04 | 2.80 | 5.98 | 10 | 16 | bile acid metabolic process | ACAA1, ALB, FABP6, NR5A2, ATP8B1, RXRA, SLC10A1, SLC10A2, SLCO1A2, SLCO1B1 |
1089 | GO:0001709 | 0.04 | 2.80 | 5.98 | 10 | 16 | cell fate determination | JAG1, ASCL1, BMP4, GATA6, IFRD1, ISL1, NTF3, NTF4, PTCH2, KLF4 |
1090 | GO:0002712 | 0.01 | 2.80 | 8.98 | 15 | 24 | regulation of B cell mediated immunity | BTK, C3, CD28, FCER1G, FCER2, HPX, IFNG, IL10, PTPN6, XCL1, STAT6, TNFSF4, UNG, WHSC1, IL27RA |
1091 | GO:0019369 | 0.01 | 2.80 | 8.98 | 15 | 24 | arachidonic acid metabolic process | ALOX12, ALOX15B, DAGLA, CBR1, CYP2A6, CYP2A13, CYP2F1, DPEP1, FAAH, GPX1, HPGD, LTA4H, PTGIS, PTGS1, AKR1C3 |
1092 | GO:0043029 | 0.01 | 2.80 | 8.98 | 15 | 24 | T cell homeostasis | BAX, BCL2, TSC22D3, IL2RA, LMO1, P2RX7, RAG1, STAT5B, FOXN1, TNFSF14, CCNB2, CHST3, BCL2L11, SIVA1, CORO1A |
1093 | GO:0043113 | 0.01 | 2.80 | 8.98 | 15 | 24 | receptor clustering | CACNA1A, DLG2, DLG3, ETV5, ITGA4, PIGR, RELN, PTN, MADCAM1, SSNA1, ITGB1BP1, NRXN1, NRXN2, PICK1, RER1 |
1094 | GO:0001556 | 0.04 | 2.79 | 5.98 | 10 | 16 | oocyte maturation | ANG, BRCA2, CCNB1, EREG, PTK2B, INSL3, PDE3A, PPP2R1A, AURKA, REC8 |
1095 | GO:0001961 | 0.04 | 2.79 | 5.98 | 10 | 16 | positive regulation of cytokine-mediated signaling pathway | AXL, GAS6, GFI1, HIF1A, UBE2K, HPX, PARK2, TRAF2, RIPK2, CPNE1 |
1096 | GO:0002053 | 0.04 | 2.79 | 5.98 | 10 | 16 | positive regulation of mesenchymal cell proliferation | BMPR1A, IHH, KDR, PRRX1, SIX1, SOX9, STAT1, WNT2, TP63, CHRD |
1097 | GO:0006699 | 0.04 | 2.79 | 5.98 | 10 | 16 | bile acid biosynthetic process | AKR1C4, CYP8B1, FGFR4, STAR, ACOX2, CH25H, NR1H4, ACOT8, SLC27A5, SLC27A2 |
1098 | GO:0006911 | 0.04 | 2.79 | 5.98 | 10 | 16 | phagocytosis, engulfment | ABCA1, CD36, CLCN3, F2RL1, FCER1G, FCGR1A, RAC1, BECN1, ELMO1, ABCA7 |
1099 | GO:0006958 | 0.04 | 2.79 | 5.98 | 10 | 16 | complement activation, classical pathway | SERPING1, C1QA, C1QB, C1QC, C1S, C3, C7, CLU, CR2, CD46 |
1100 | GO:0010658 | 0.04 | 2.79 | 5.98 | 10 | 16 | striated muscle cell apoptotic process | APAF1, BNIP3, CAMK2A, GNB1, GNGT1, NRG1, HMGCR, ILK, BAG3, RAPGEF3 |
1101 | GO:0021955 | 0.04 | 2.79 | 5.98 | 10 | 16 | central nervous system neuron axonogenesis | CHRNB2, DCC, DCX, EPHB1, EPHB3, PTEN, PTK2, PHOX2B, SLIT2, ATG7 |
1102 | GO:0045214 | 0.04 | 2.79 | 5.98 | 10 | 16 | sarcomere organization | ACTG1, CASQ1, CASQ2, CAV3, CFL2, ITGB1, KRT19, PRKAR1A, SRF, TNNT2 |
1103 | GO:0051955 | 0.04 | 2.79 | 5.98 | 10 | 16 | regulation of amino acid transport | ABAT, ARG1, ATP1A2, AVP, CCK, IL1B, SEPT2, NTSR1, P2RX7, SNCA |
1104 | GO:0060292 | 0.04 | 2.79 | 5.98 | 10 | 16 | long term synaptic depression | ARF1, CD38, DRD5, PTK2B, GRIA1, PTEN, SRF, STXBP1, DGKI, PICK1 |
1105 | GO:0060999 | 0.04 | 2.79 | 5.98 | 10 | 16 | positive regulation of dendritic spine development | ARF1, LPAR1, GRN, NRG1, CAPRIN1, PALM, RELN, PSEN1, CAMK1, BAIAP2 |
1106 | GO:0061418 | 0.04 | 2.79 | 5.98 | 10 | 16 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | ARNT, BACH1, EP300, HIF1A, RBPJ, UBB, UBE2D2, CUL2, RBX1, CITED2 |
1107 | GO:0071549 | 0.04 | 2.79 | 5.98 | 10 | 16 | cellular response to dexamethasone stimulus | AGTR2, ARG1, ASS1, CASP9, CRH, DNMT3B, HMBS, SERPINF1, SRD5A1, STAR |
1108 | GO:1900740 | 0.04 | 2.79 | 5.98 | 10 | 16 | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | BAD, BCL2, BID, SFN, PPP3R1, MAPK8, YWHAZ, DYNLL1, BCL2L11, YWHAQ |
1109 | GO:1902235 | 0.04 | 2.79 | 5.98 | 10 | 16 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | DDIT3, GRINA, OPA1, PARK2, PTPN1, WFS1, EIF2AK3, BCL2L11, CREB3, SERINC3 |
1110 | GO:1902624 | 0.04 | 2.79 | 5.98 | 10 | 16 | positive regulation of neutrophil migration | EDNRA, CXCL1, CXCL3, IL1B, PAWR, PTGER4, RAC1, RAC2, CCL21, XCL1 |
1111 | GO:0050852 | 0.00 | 2.79 | 36.65 | 61 | 98 | T cell receptor signaling pathway | CACNB3, CACNB4, CBLB, CD3D, CD3E, CD3G, CD4, CD28, CHUK, FYB, FYN, HLA-DQA1, KCNN4, PAWR, PDE4B, PDE4D, PIK3CB, PRKCQ, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTPN6, PTPRJ, SKP1, STK11, UBB, UBE2D2, CUL1, IKBKG, RIPK2, GRAP2, THEMIS2, PSMF1, BCAR1, PSMD6, PSME3, PSMD14, RBCK1, MALT1, BTN3A1 |
1112 | GO:0023061 | 0.00 | 2.79 | 61.37 | 102 | 165 | signal release | ACVR2B, ADCY5, ADM, ADRA2A, AGTR1, AGTR2, ANXA1, ANXA5, ARL2, ARNTL, BAD, BLK, BMP6, CD38, CFTR, CHRM3, CNR1, CREB1, CRH, CRHBP, CRY1, EDN3, EFNA5, EPHA5, FGA, FGG, GALR1, GCG, GDF9, GHRH, GHRHR, GHSR, GLP1R, GLUD1, GLUL, GNAS, GPLD1, GPR27, FFAR1, FFAR3, HIF1A, HMGCR, FOXA2, HTR2C, IFNG, IL1B, IL1RN, INHA, INS, ISL1, ITPR1, ITPR2, KCNC2, KCNJ11, KCNS3, KISS1, OXCT1, P2RY1, PDE3B, PDE4C, PFKFB2, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PTGS1, PTPRN, RAB1A, RAF1, REST, RFX3, SLC2A1, SLC16A1, SOX11, SREBF1, STXBP3, ABCC8, SYT5, TAC1, HNF1A, TMF1, TRPM2, UCN, VIP, PAX8, FGF23, FZD4, VAMP8, ARHGEF7, SYT7, HMGN3, EIF2AK3, STXBP5L, CLOCK, C2CD2L, NR1H4, RAPGEF3, RAPGEF4, CAPN10 |
1113 | GO:0043401 | 0.00 | 2.79 | 33.66 | 56 | 90 | steroid hormone mediated signaling pathway | NR0B1, ARNTL, BMP4, BRCA1, CCNE1, CRY1, CRY2, DAB2, DDX5, EP300, ESR1, ESRRG, NR5A2, NR5A1, NR6A1, GHRHR, NR4A1, HNF4G, PRMT2, IGF1, ISL1, SCGB2A1, CNOT2, PER1, PGR, PPP5C, RAN, RARA, RARB, RB1, RNF6, RXRA, RXRG, SGK1, SMARCA4, TAF7, NR2F1, NR2F2, NR2C1, NR2C2, UBE3A, NR1H2, NRIP1, BUD31, RQCD1, CLOCK, RNF14, NR1I3, NR1H4, NR1D2, NR2E3, HDAC6, PGRMC2, RBM14, CARM1, AKAP13 |
1114 | GO:0006090 | 0.00 | 2.78 | 19.82 | 33 | 53 | pyruvate metabolic process | AGXT, ALDOB, ALDOC, ARNT, BSG, ENO2, ENO3, GAPDH, GPD1, HIF1A, IGF1, INS, LDHA, LDHC, OGDH, P2RX7, PCK1, PDK4, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PGM1, PPP2R5D, PRKAA1, PRKAG1, SLC16A1, STAT3, PDHX, OGT, HDAC4, SDS |
1115 | GO:0006521 | 0.00 | 2.78 | 19.82 | 33 | 53 | regulation of cellular amino acid metabolic process | BHMT, COMT, INS, OAZ1, OAZ2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PAX8, PSMF1, PSMD6, NR1H4, PSME3, PSMD14 |
1116 | GO:0044419 | 0.00 | 2.78 | 136.62 | 225 | 369 | interspecies interaction between organisms | ADAR, ADARB1, AMBP, TRIM23, ARF1, BAX, BCL2, BICD1, BNIP3, BNIP3L, BST2, CCNH, CCNT1, CCNT2, CD8B, CD28, CD36, CDC25C, CDK9, CENPA, AP1S1, AP2S1, CCR3, CREB1, CX3CR1, DDX5, DDX6, DMBT1, DYNC1I2, E4F1, EPHA2, EIF4A1, EIF4E, EIF4G1, ERCC3, FAU, FDPS, NR5A2, FYN, KAT2A, GFI1, GRB2, GTF2F1, HCK, HMGA1, HPX, HSPA8, HSP90AB1, IFI16, SP110, IFNG, IL10, IL12B, ILF3, ISG20, KDR, KLC1, TNPO1, IPO5, KRT18, KRT19, MAP3K5, RPL10A, OAS3, OSBP, CHMP1A, PCSK5, PPID, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, RAB1A, RAB6A, RAC1, RALA, RAN, RANBP1, RB1, RBL1, ABCE1, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, SATB1, SET, SGTA, SHC1, SKP1, SLPI, SP100, SRPK2, SSRP1, STAT1, STAT2, STAT3, STAU1, SUPT4H1, SUV39H1, TAF2, TAF4B, TAF5, TAF6, TAF10, TAF13, TBP, TSPAN7, TNFRSF1A, TOP1, TOP2A, TP73, TSC2, TSG101, UBB, UBE3A, SUMO1, UNG, USF1, VCAM1, VIM, VRK2, EIF4H, XRCC4, XRCC5, RAB7A, CUL4A, CUL2, CUL1, IKBKG, CDK13, DYNLL1, EIF4G3, BECN1, RNGTT, BANF1, CFLAR, KAT2B, AP1S2, AP1M1, RPL14, CLDN6, CTDP1, RPL23, ATG5, PSMF1, KDM4A, IST1, CUL7, ELMO1, PSMD6, RBX1, ACOT8, ABI1, PDCD6IP, AP1M2, RAD50, ABI2, WASF2, PSME3, TRIM13, PSMD14, TRIM22, PPIE, PPIH, NXF1, CREB3, CARM1, RBCK1, IVNS1ABP, CXCR6, ZMYND11, COPS6, PSIP1, SUPT16H, RPL35 |
1117 | GO:0008284 | 0.00 | 2.78 | 87.90 | 146 | 239 | positive regulation of cell proliferation | ABL1, ADAM10, ADM, ADRA2A, ADRB2, AGTR2, ALDH3A1, BIRC5, AREG, STS, ASCL1, AVP, AVPR2, BCL2L1, CAPN1, CAV3, RUNX2, CCK, CDC20, CDK2, CDX2, CGA, CHRM1, CLU, CNTF, CLDN7, CRH, CRKL, CSF1R, CSNK2A1, CTF1, CTGF, CTSH, CX3CR1, DPP4, DRD3, S1PR3, EDN3, EDNRA, EGR4, EIF5A, EMP2, EPHA1, ETS1, F2, F2R, PTK2B, EFEMP1, FGF3, FGF4, FGF5, FGFR4, FLT3, FLT3LG, FSHB, GDF9, GHRH, GHRHR, HCK, HCLS1, HGF, HLX, HMX2, HOXC10, HSF4, IGF1R, IL12RB2, ILK, INS, INSL3, ISL1, ITGAV, ITGB1, KIT, KRAS, LTF, EPCAM, YBX1, NTF3, NTRK2, NTRK3, PAX3, PBX1, PGGT1B, PRRX1, PRKAA1, PRKCZ, PTEN, PTGER4, PTHLH, PTK2, PTPN6, PURA, RAC2, RAD51B, RARA, RARB, REG1A, RPS4X, RSU1, S100A13, S100B, TSPAN31, SERPINB3, CLEC11A, CXCL5, SDCBP, SHMT2, ST8SIA1, SIX1, SMARCD3, SOX2, SOX10, SRPK2, SSR1, STAT3, ADAM17, TTK, VIPR1, CNBP, ZNF16, FOSL1, HMGA2, CUL4A, CUL3, CDK13, AKR1C3, CHRD, SERPINB7, TSC22D1, ALDH1A2, CDC123, CCPG1, CRLF1, ITGB1BP1, S1PR2, CNOT8, GLP2R, CIAO1, GAB2, FGFBP1, CARM1, STAMBP, PRDX3, IL24, ESM1 |
1118 | GO:0015718 | 0.00 | 2.77 | 24.64 | 41 | 66 | monocarboxylic acid transport | ABAT, ACACB, AGTR2, AKT2, ABCD1, ANXA1, BDKRB2, CACNA1A, CACNB4, CD36, CPT1B, CPT2, ACE, DRD3, ACSL1, ACSL3, ACSL4, GOT2, IL1B, NTSR1, P2RX4, P2RX7, P2RY2, ABCD3, SLC6A11, SLC6A12, SLC6A13, SLC16A1, SLCO2A1, SLC22A5, TRPC4, SLC5A6, SLC16A6, SLC16A5, SLC16A4, SLC16A7, SLC22A13, ABCC4, SLC25A17, SLC27A4, SLC27A2 |
1119 | GO:0002429 | 0.00 | 2.77 | 69.57 | 115 | 186 | immune response-activating cell surface receptor signaling pathway | ABL1, ACTB, ACTG1, BAX, BCL2, BLK, BTK, CACNB3, CACNB4, CALM1, CALM3, CBLB, CD3D, CD3E, CD3G, CD4, CD28, CD38, CD79B, CDC42, CHUK, CR2, CTLA4, EP300, FCER1G, FCGR1A, FGR, FYB, FYN, GPLD1, GRB2, HCK, HLA-DQA1, HSP90AA1, HSP90AB1, ICAM2, ICAM3, IL1B, ITPR1, ITPR2, KCNN4, KRAS, LIMK1, PAWR, PDE4B, PDE4D, PIK3CB, PPP3R1, PRKACB, PRKACG, PRKCD, PRKCE, PRKCQ, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, PTPN6, PTPRJ, RAC1, RAF1, RELB, SKP1, STK11, UBB, UBE2D2, VAV1, LAT2, CUL1, IKBKG, RIPK2, UBA3, GRAP2, THEMIS2, PSMF1, BCAR1, ELMO1, PSMD6, ABI1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, WASF2, PSME3, PSMD14, VAV3, BAIAP2, ARPC1A, RBCK1, MALT1, BTN3A1 |
1120 | GO:0042100 | 0.00 | 2.77 | 13.83 | 23 | 37 | B cell proliferation | ABL1, BAX, BCL2, CD38, CD81, CDKN1A, CHRNB2, CR2, CTPS1, GPR183, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IL13, CD180, PRKCD, RAG2, TNFRSF4, VAV3, TNFSF13B |
1121 | GO:0007193 | 0.00 | 2.76 | 13.84 | 23 | 37 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | ADCY3, ADCY5, ADCY6, ADCY9, ADRA2A, APLP1, CHRM1, CHRM3, CORT, DRD3, S1PR1, LPAR1, S1PR3, GNAI1, GNAL, GNAZ, FFAR3, GRIK3, GRM8, INSL3, P2RY1, PSAP, SSTR2 |
1122 | GO:0032508 | 0.00 | 2.76 | 13.84 | 23 | 37 | DNA duplex unwinding | ANXA1, ATRX, CHD1, CHD2, CHD3, CHD4, DDX1, DHX9, ERCC3, HMGA1, PURA, RAD51, SUPV3L1, XRCC5, RUVBL1, RECQL5, RECQL4, CHD1L, GINS1, RAD50, G3BP1, RUVBL2, ASCC3 |
1123 | GO:0071453 | 0.00 | 2.76 | 29.55 | 49 | 79 | cellular response to oxygen levels | ADRB2, ARNT, BACH1, BAD, BCL2, BDKRB2, BNIP3, BNIP3L, CCNB1, CLCA1, DNMT3B, LPAR1, EIF4EBP1, EP300, GATA6, GNB1, GNGT1, HIF1A, ICAM1, RBPJ, IRAK1, KCND2, KCNK2, KCNK3, PRKAA1, PRKCE, PTEN, PTGIS, PTN, S100B, SLC2A4, SLC8A3, SLC9A1, STC1, SUV39H1, TRPC1, TSC1, TWIST1, UBB, UBE2D2, CUL2, OGT, AIFM1, PICK1, RBX1, CITED2, ACAA2, ATG7, USP19 |
1124 | GO:0007200 | 0.01 | 2.76 | 10.82 | 18 | 29 | phospholipase C-activating G-protein coupled receptor signaling pathway | ADRA1B, ADRA2A, BICD1, CHRM1, CHRM3, LTB4R, ESR1, F2, FPR1, GNB1, UTS2R, GPR27, HRH1, P2RY1, P2RY2, P2RY4, P2RY6, P2RY11 |
1125 | GO:0097530 | 0.00 | 2.76 | 21.69 | 36 | 58 | granulocyte migration | ANXA1, CXADR, EDN3, EDNRA, FCER1G, CXCL1, CXCL3, HRH1, IFNG, IL1B, ITGA1, ITGA9, PAWR, PDE4B, PDE4D, PTGER4, RAC1, RAC2, S100A7, S100A8, S100A9, S100A12, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, XCL2, VAV1, SCG2, EPX, TNFSF18, SLIT2, VAV3 |
1126 | GO:0048709 | 0.01 | 2.76 | 10.83 | 18 | 29 | oligodendrocyte differentiation | BMP4, BOK, CNP, DRD3, ERBB2, NRG1, HES1, NTRK2, PTPRJ, RHEB, SLC8A3, SOX9, SOX10, TP73, TRPC4, VTN, TSPAN2, OLIG2 |
1127 | GO:1904589 | 0.00 | 2.76 | 34.41 | 57 | 92 | regulation of protein import | AGTR2, ANGPT1, BCL3, BMP4, BMP6, BMPR1A, BRCA1, CD36, CDH1, CDKN1A, CYLD, DAB2, EDA, GAS6, GNAQ, HCLS1, HSPA8, HSP90AB1, IGF1, IL1B, IL10, IL12B, IL18, KPNA1, IPO5, SMAD3, TONSL, OGG1, PRDX1, PPM1A, PPM1B, PPP3R1, PRKCD, PRKCQ, SFRP5, SLC9A1, TRIP6, ZIC1, ARHGEF5, AKAP1, FZD7, DYRK2, RGS20, TNFSF14, HDAC3, SEMA5A, SLC9A3R1, AKAP6, LITAF, KEAP1, NUTF2, APC2, TACC3, CREB3, CHERP, RBCK1, EDAR |
1128 | GO:0000060 | 0.01 | 2.75 | 10.85 | 18 | 29 | protein import into nucleus, translocation | ARNTL, BCL3, BRCA1, CDKN1A, GAS6, HSP90AB1, IFNG, IGF1, TNPO1, IPO5, OGG1, OR1D2, RAN, SIX3, SLC11A1, AKR1C3, NUTF2, SEC61B |
1129 | GO:0071695 | 0.01 | 2.75 | 10.85 | 18 | 29 | anatomical structure maturation | ACVRL1, ARCN1, RERE, CACNA1A, CDH3, DDIT3, S1PR1, FGFR3, IGF1, RBPJ, LTF, RYR1, WNT1, RECK, DCHS1, ALDH1A2, SEMA4D, SPINK5 |
1130 | GO:0032231 | 0.00 | 2.75 | 18.70 | 31 | 50 | regulation of actin filament bundle assembly | APOA1, ARHGAP6, BBS4, CTGF, S1PR1, LPAR1, EPHA1, LIMK1, TACSTD2, SMAD3, PARK2, PFN1, PFN2, PRKCQ, PTGER4, RAC1, RDX, S100A10, SDC4, SLC9A1, TAC1, TSC1, VIL1, WNT11, ALMS1, ARHGEF5, ITGB1BP1, BAG4, WASF2, SORBS3, RAPGEF3 |
1131 | GO:0007423 | 0.00 | 2.75 | 14.40 | 24 | 39 | sensory organ development | ASCL1, C1QB, DFNA5, GABRA5, HES1, IGF1, RBPJ, KCNK2, KCNK3, KCNQ1, NTF4, ATP8B1, SDC4, SOX3, SPARC, USH2A, DCHS1, LIN7A, PHOX2B, SLC9A3R2, ATG5, CXCL14, KCNE2, BCL2L11 |
1132 | GO:0010811 | 0.02 | 2.75 | 7.82 | 13 | 21 | positive regulation of cell-substrate adhesion | ARL2, ECM2, FBLN1, FBLN2, ITGA3, ITGA5, ITGB1, VIT, PRKCE, PTN, RSU1, VTN, SPOCK2 |
1133 | GO:0071216 | 0.00 | 2.75 | 36.28 | 60 | 97 | cellular response to biotic stimulus | ABCA1, ABL1, APAF1, ARG1, ASS1, AXL, PRDM1, BMP6, BYSL, TSPO, CD6, CD80, CD86, CD36, ENTPD2, CEBPE, CCR5, CX3CR1, DDIT3, GFI1, HCK, HIF1A, HMGCS2, ICAM1, IFNG, IL1B, IL10, IL12B, IL18, IRAK1, IRAK2, LTF, CD180, P2RY2, SERPINE1, PDE4B, PDE4D, PRKCE, MAPK8, PTAFR, RARA, UPF1, CCL20, STAR, STAT1, TNFAIP3, TNFRSF1B, TNFSF4, WFS1, FZD5, OGT, ADAM9, RIPK2, EIF2AK3, LITAF, CTR9, TRIB1, SPON2, TXNIP, IL24 |
1134 | GO:0050796 | 0.00 | 2.74 | 41.14 | 68 | 110 | regulation of insulin secretion | ABAT, ADCY5, ADRA2A, ARL2, ARNTL, BAD, BLK, CACNA1A, CD38, CFTR, CHRM3, CNR1, CRH, EFNA5, EPHA5, GCG, GHSR, GLP1R, GLUD1, GLUL, GNAS, GPLD1, GPR27, FFAR1, HIF1A, HMGCR, FOXA2, IFNG, IL1B, INS, ISL1, ITPR1, ITPR2, KCNC2, KCNJ11, KCNS3, OXCT1, PARK2, PDE3B, PDE4C, PFKFB2, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, REST, RFX3, SLC2A1, SLC16A1, SNAP25, SREBF1, STXBP1, ABCC8, SYT5, TRPM2, SYT7, HMGN3, NRXN1, STXBP5L, CLOCK, C2CD2L, NR1H4, RAPGEF3, RAPGEF4, CAPN10 |
1135 | GO:0006091 | 0.00 | 2.74 | 68.59 | 113 | 184 | generation of precursor metabolites and energy | ACACB, ACADVL, ACLY, ACO1, ACO2, ADCY3, ADCY5, ADCY6, ADCY9, ADRA2A, ADSL, AK2, AQP7, ARL2, ASIP, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP5O, AVP, BAX, CACNA1A, CALM1, CALM3, CAT, RUNX1T1, CHRM3, COX4I1, COX5B, COX6A1, COX6B1, COX7A1, COX7C, COX8A, COX15, CPS1, CYC1, FDXR, G6PC, GAA, GCG, BLOC1S1, GLP1R, GNAS, GNB1, GNG3, GNG10, GNG11, FFAR1, GYS2, IDH1, IDH3A, ITPR1, ITPR2, KCNC2, KCNJ11, KCNS3, MDH1, MDH2, PHKA1, PHKA2, PHKB, PHKG1, PPP1R1A, PPP1R2, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PYGB, PYGL, PYGM, SCO1, SDHA, SDHB, SDHC, SDHD, SLC1A3, SLC2A1, SNAP25, STK11, STXBP1, ABCC8, SYT5, TAZ, UBB, UCN, UCP1, UGP2, UQCRC1, UQCRC2, UQCRH, EPM2A, SLC25A12, SUCLG2, SUCLG1, SUCLA2, COX7A2L, ATP5J2, XYLB, COX17, SLC25A13, RAPGEF3, ATP5H, ATP5L, UQCR11, RAPGEF4 |
1136 | GO:0031623 | 0.00 | 2.74 | 15.70 | 26 | 42 | receptor internalization | ACHE, ANGPT1, ARF1, CALCR, CAV3, CD9, CD36, CD63, CD81, FCER1G, GRB2, GRIA1, ITGB1, NTF3, RAB5A, SDCBP, SELE, SFRP4, SNCA, CNTN2, PICALM, PICK1, CALCRL, RAMP2, RAMP3, RAB31 |
1137 | GO:0071214 | 0.00 | 2.74 | 35.61 | 59 | 96 | cellular response to abiotic stimulus | ASCL1, ATF4, ATM, ATR, BAX, BCL2L1, CALM1, CALM3, CASP9, CDC25A, CDKN1A, CNGA1, CRY1, CRY2, DDB2, DNM2, EIF2S1, ELK1, EP300, ERCC4, GNB1, GNGT1, GPLD1, GRB2, GUCA1A, GUCA1B, GUCY2F, GUCY2D, IFI16, INSRR, MGMT, PCK1, PCNA, PDE6G, PPID, PRKCQ, PTAFR, PTN, RAD1, RAD51, RCVRN, RPGR, RS1, SAG, SIPA1, STK11, TP73, XPC, XRCC5, YY1, HMGA2, TP63, SLC24A1, AURKB, CLOCK, GUCA1C, RAD51AP1, CERS1, RUVBL2 |
1138 | GO:0060548 | 0.00 | 2.73 | 154.54 | 252 | 416 | negative regulation of cell death | ABL1, ABL2, ACVR1, ADAR, AKT2, ALB, ALOX12, ANXA1, ANXA5, BIRC2, BIRC3, XIAP, BIRC5, APOH, ARAF, ASCL1, ATOH1, AVP, BAD, BAG1, BARD1, BCL2A1, BCL3, BDKRB2, BLK, BMP4, BNIP2, BNIP3, BNIP3L, BRCA1, CAT, CBL, KRIT1, CD38, CD44, CD59, CDKN1A, CLU, COMP, CLDN7, CRH, CSF1R, CSNK2A1, CTGF, CTH, CTNNA1, CTSH, CX3CR1, DAB2, DAD1, DFFA, DHCR24, DPEP1, TSC22D3, DUSP1, EDNRA, EGR3, CTTN, ERCC5, EYA1, FCER1G, FGA, FGF4, FGG, FLT4, GAS6, GATA6, GCG, SFN, GPX1, GRINA, HCK, HCLS1, HGF, NRG1, HMGCR, HSPA9, HSPB1, ICAM1, IFIT3, IGBP1, IGF1R, IHH, IL1A, IL1B, IL10, IDO1, ING2, INS, INSL3, IRAK1, ITGA5, ITGAV, ITGB1, KCNJ1, KDR, KIT, KRT18, LTF, EPCAM, SMAD3, SMAD6, KITLG, MGMT, YBX1, NTRK3, NTSR1, OGG1, OPA1, PA2G4, PAFAH2, SERPINE1, SERPINB2, PAX4, PDE3A, PDK4, PF4, SERPINB9, SERPINB13, PIM1, PRKAA1, PRKCD, PRKD1, PRKCQ, PRKCZ, MAPK8, EIF2AK2, PROC, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, PTPN1, PYCR1, RAF1, RAG1, RARA, RARB, RPS3A, RPS6KA1, RPS6KB1, CCL21, CX3CL1, SRSF6, SGK1, ST6GAL1, STIL, SLC9A1, SNAI1, SON, SOX9, SOX10, SOX11, STAT5B, AURKA, SUPV3L1, TMF1, TNFAIP3, TPT1, HSP90B1, TWIST1, UBB, UNG, VDAC2, VIL1, VIP, WNT1, WNT11, YWHAZ, ZNF16, PAX8, SCG2, HMGA2, OGT, CBX4, API5, TP63, BECN1, PEA15, TRADD, URI1, RIPK1, TNFSF14, TNFSF10, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, CFLAR, WISP3, WISP1, HDAC3, TSC22D1, TAX1BP1, TNFSF18, SOCS3, SEMA5A, RGN, ARHGEF2, AURKB, KLF4, EIF2AK3, ATG5, PSMF1, BAG5, BAG4, BAG3, RB1CC1, PSMD6, NR1H4, BCL2L10, TRAP1, PSME3, DHRS2, PSMD14, RAMP2, CITED2, RAPGEF3, ACAA2, CREB3, SEMA4D, ATG7, RBCK1, IVNS1ABP, ZMYND11, PROKR1, MALT1, PRDX3, PIM2 |
1139 | GO:0090087 | 0.01 | 2.73 | 9.63 | 16 | 26 | regulation of peptide transport | BCL3, CA2, CYLD, EDA, IL10, IL12B, IL18, PRDX1, PPM1A, PPM1B, PRKCQ, TRIP6, TNFSF14, LITAF, RBCK1, EDAR |
1140 | GO:0017038 | 0.01 | 2.73 | 9.63 | 16 | 26 | protein import | CLU, HSPA4, HSP90AA1, LAMP2, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX14, PEX19, PEX5, PEX16, TOMM20, AFG3L2 |
1141 | GO:0009268 | 0.02 | 2.73 | 7.85 | 13 | 21 | response to pH | STS, CA2, CLCN7, GJA3, GPLD1, INSRR, KCNJ8, PAM, PCK1, SERPINF1, SLC9A1, ABCC8, TRPV1 |
1142 | GO:0032720 | 0.02 | 2.73 | 7.85 | 13 | 21 | negative regulation of tumor necrosis factor production | AXL, BCL3, BPI, TSPO, GAS6, GHSR, IL10, PTGER4, RARA, TNFAIP3, TWIST1, NR1H4, GPNMB |
1143 | GO:0035272 | 0.02 | 2.73 | 7.85 | 13 | 21 | exocrine system development | CDC42, EDA, FGF7, HGF, IGF1, IGF1R, IGF2, LAMA5, SOX9, SOX10, NRP1, SEMA3A, EDAR |
1144 | GO:0035987 | 0.02 | 2.73 | 7.85 | 13 | 21 | endodermal cell differentiation | COL5A2, COL6A1, COL11A1, COL12A1, GATA6, ITGA4, ITGA5, ITGAV, LAMA3, SOX2, VTN, HMGA2, CTR9 |
1145 | GO:0045843 | 0.02 | 2.73 | 7.85 | 13 | 21 | negative regulation of striated muscle tissue development | BMP4, CAV3, CXADR, TSC22D3, FGF3, KCNK2, S100B, TP73, TWIST1, HDAC3, USP2, CTDP1, USP19 |
1146 | GO:0046580 | 0.02 | 2.73 | 7.85 | 13 | 21 | negative regulation of Ras protein signal transduction | ABL2, RAPGEF1, ARHGAP35, ITGA3, ITGB1, PPP2CB, RASA2, CUL3, DGKZ, TNK1, RASA4, SPRY1, STAMBP |
1147 | GO:0031145 | 0.00 | 2.73 | 25.43 | 42 | 68 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | BUB1B, CCNB1, CDC20, CDC27, CDK2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, SKP1, AURKA, UBB, CUL1, CDC23, CDC16, AURKB, PSMF1, PSMD6, PSME3, PSMD14, ANAPC10, MAD2L2, UBE2C |
1148 | GO:0046718 | 0.00 | 2.73 | 25.43 | 42 | 68 | viral entry into host cell | APCS, AXL, CAV2, CD4, CD80, CD86, SCARB2, CD81, CCR5, CR2, CXADR, DPP4, EPS15, GAS6, GYPA, ICAM1, IDE, IFNA2, ITGA5, ITGAV, ITGB1, KPNA3, CD46, PVR, SERPINB3, SELPLG, SLC10A1, TRIM21, DYNLT1, TMPRSS2, TNFRSF4, TYRO3, UVRAG, TRIM25, VAMP8, CLDN1, IFITM3, TRIM38, SIVA1, IFITM2, WWP1, WWP2 |
1149 | GO:2000134 | 0.00 | 2.73 | 25.43 | 42 | 68 | negative regulation of G1/S transition of mitotic cell cycle | ATM, CCND1, BCL2, CDK2, CDKN1A, PRMT2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, RB1, RPA2, SMARCA4, TP73, UBB, DGKZ, TP63, CRADD, PSMF1, PSMD6, PSME3, PSMD14, CTDSPL |
1150 | GO:0007189 | 0.00 | 2.72 | 12.70 | 21 | 34 | adenylate cyclase-activating G-protein coupled receptor signaling pathway | ADCY3, ADCY6, ADCY9, ADRA1B, ADRA2A, ADRB2, CALCR, FSHR, GALR1, GHRH, GHRHR, GNAQ, GPR3, GPR26, PDE4D, PTGER2, PTHLH, VIP, S1PR4, RAPGEF2, CALCRL |
1151 | GO:0002275 | 0.00 | 2.71 | 12.72 | 21 | 34 | myeloid cell activation involved in immune response | ANXA3, BCR, CX3CR1, F2RL1, FCER1G, FGR, IL13, IL13RA2, KIT, PRKCE, PTAFR, RAC2, S100A13, STXBP2, STXBP3, TYROBP, LAT2, VAMP8, STX11, GAB2, CPLX2 |
1152 | GO:0060135 | 0.00 | 2.71 | 12.72 | 21 | 34 | maternal process involved in female pregnancy | ANGPT2, ARG1, PRDM1, BMPR2, BSG, CNR1, CTSV, ESR1, GHSR, HIF1A, IHH, ITGA3, ITGB1, PAM, PGR, PTGIS, RXRA, STC1, NR2F2, PRDX3, TMED2 |
1153 | GO:0034284 | 0.00 | 2.71 | 14.51 | 24 | 39 | response to monosaccharide | ACVR2B, ALDOB, ANGPT2, CAT, COL6A2, CTGF, CTSV, EIF2B1, PTK2B, GLUL, GYS2, HMGCS2, KHK, LDHA, PFKFB2, PRKCQ, PTEN, RPS6KB1, SPARC, SREBF1, EIF2B3, EIF2B2, EIF2B5, TXNIP |
1154 | GO:0045740 | 0.00 | 2.71 | 17.58 | 29 | 47 | positive regulation of DNA replication | AREG, ATM, ATR, ATRX, BMP4, BMP6, CCT6A, CDC42, CDK2, DKC1, EREG, IGF1, IGF1R, INS, JUN, KITLG, NVL, PCNA, PRKCQ, RAC1, SHC1, CCT3, UCN, MAPKAPK5, AURKB, KLF4, CCT7, CCT4, CCT2 |
1155 | GO:0046717 | 0.01 | 2.70 | 9.70 | 16 | 26 | acid secretion | AGTR2, AGXT, ANXA1, BDKRB2, ACE, DRD3, ACSL4, HRH2, KCNQ1, OXTR, P2RX4, P2RY2, SGK1, UCN, SLC9A3R1, ABCC4 |
1156 | GO:0015844 | 0.00 | 2.69 | 14.59 | 24 | 39 | monoamine transport | ABAT, ADRA2A, AGTR2, CHRNB2, CNR1, CRH, DRD3, FCER1G, FFAR3, KCNA2, OXTR, P2RX1, P2RY1, PARK2, PCP4, PTGS1, RAB3B, SLC18A1, SLC22A1, SLC22A3, SLC22A2, SNCA, CADPS, PICK1 |
1157 | GO:0050795 | 0.00 | 2.69 | 41.45 | 68 | 111 | regulation of behavior | ADAM10, AKT2, ANGPT2, BMPR2, CNR1, S1PR1, LPAR1, EDN3, EDNRA, F2RL1, F3, F7, PTK2B, FGF4, GAS6, CXCL1, CXCL3, HRG, HSPB1, IL1B, INS, KDR, SMAD3, NTF3, NTRK3, SERPINE1, PENK, PF4, PF4V1, PRKD1, RELN, RAC1, RAC2, S100A7, CCL21, CXCL6, CXCL5, XCL1, CX3CL1, SEMA3F, ST6GAL1, STAT3, ADAM17, TACR3, NR2C2, UCN, VEGFB, VEGFC, SCG2, SEMA3B, TNFSF14, NRP1, TNFSF18, SEMA5A, USP14, SLIT2, NRXN1, CXCL14, SEMA3E, SEMA3A, CREB3, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, CXCL13, TBR1 |
1158 | GO:0031667 | 0.01 | 2.69 | 10.25 | 17 | 28 | response to nutrient levels | ACACB, AKT2, CYBA, HTR2C, ICAM1, IGF2, LIPC, NTRK1, PYY, PSPH, SLC22A3, SOD1, SORD, TRPV1, WNT11, AIFM1, SLIT2 |
1159 | GO:0009948 | 0.01 | 2.69 | 9.72 | 16 | 26 | anterior/posterior axis specification | BMP4, CDX1, CDX2, CDX4, DDIT3, GPC3, HHEX, FOXA2, HOXD8, OTX2, PCSK6, SRF, AURKA, KDM6A, FZD5, CER1 |
1160 | GO:0048146 | 0.01 | 2.69 | 9.72 | 16 | 26 | positive regulation of fibroblast proliferation | BMI1, CCNB1, CDK4, CDK6, CDKN1A, EREG, ESR1, FBLN1, GAS6, UTS2R, IGF1, IL13, JUN, S100A6, WNT1, WNT2 |
1161 | GO:0051196 | 0.01 | 2.69 | 9.72 | 16 | 26 | regulation of coenzyme metabolic process | ARNT, GPD1, HIF1A, IGF1, INS, P2RX7, PDK4, PGAM1, PGAM2, PRKAA1, PRKAG1, SNCA, STAT3, PDHX, OGT, HDAC4 |
1162 | GO:0046883 | 0.00 | 2.68 | 33.48 | 55 | 90 | regulation of hormone secretion | ADCY5, ADRA2A, ANXA1, ANXA5, ARL2, ARNTL, CACNA1A, CHRM3, CNR1, CRHBP, EFNA5, EPHA5, GHSR, GLP1R, GNAS, FFAR3, HMGCR, FOXA2, HTR2C, IFNG, IL1B, ITPR1, ITPR2, KCNC2, KCNJ11, KCNS3, PARK2, PDE3B, PDE4C, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PTGS1, REST, RFX3, SLC2A1, SLC16A1, SNAP25, SREBF1, STXBP1, ABCC8, SYT5, PAX8, FGF23, SYT7, HMGN3, NRXN1, STXBP5L, CLOCK, NR1H4, RAPGEF3, RAPGEF4 |
1163 | GO:0038095 | 0.00 | 2.68 | 62.46 | 102 | 167 | Fc-epsilon receptor signaling pathway | ANGPT1, ARAF, BAD, BTK, CALM1, CALM3, CAMK2A, CASP9, CD28, CD80, CD86, CDKN1A, CHUK, CREB1, CSF2RB, HBEGF, DUSP5, ERBB2, EREG, FCER1G, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FYN, GRB2, GRIN2A, NRG1, NR4A1, IL2RA, ITPR1, ITPR2, JUN, KIT, KRAS, MARK3, KITLG, FOXO4, PEBP1, PIK3CB, PPP3R1, PPP5C, PRKCQ, MAPK8, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, PTPRA, RAC1, RAF1, RASA2, RPS6KB2, SHC1, SKP1, SOS1, TSC2, UBB, UBE2D2, VAV1, LAT2, FGF23, CUL3, CUL1, IKBKG, PEA15, GRAP2, PSMF1, NRG2, RAPGEF2, GAB2, PSMD6, RBX1, AKAP9, RASA4, PSME3, PSMD14, VAV3, FRS3, MALT1 |
1164 | GO:0048608 | 0.00 | 2.67 | 34.06 | 56 | 92 | reproductive structure development | ACVR2A, NR0B1, AMHR2, ATRX, AXL, CCND1, BMP6, BOK, BRCA2, COL9A3, DHCR24, ERCC1, FANCA, NR5A1, GATA4, GATA6, GDF9, HSD17B10, HMGCS1, IDH1, ING2, INSL3, NTRK1, PGR, PRKACG, PTPRN, RAB13, RRM1, SALL1, SLIT3, SOX2, SRD5A1, SRY, STAR, STAT5B, TMF1, TSPY1, TYRO3, UBB, WNT2B, CSDE1, NRIP1, FZD4, AKR1C3, ADAM15, EIF2S2, SLIT2, ADAMTS1, REC8, BCL2L11, AKAP9, IRX5, FSTL3, CITED2, SEMA3A, PRDX4 |
1165 | GO:0007159 | 0.00 | 2.67 | 44.49 | 73 | 120 | leukocyte cell-cell adhesion | ABL1, ABL2, BAX, BCL2, BCL3, ZFP36L2, CAMK4, RUNX2, CCND3, CD7, CD8A, CD8B, TNFSF8, CD151, CDK6, CLC, CTPS1, CXADR, F2RL1, FCER1G, FLT3, ICAM1, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, INS, ITGA5, ITGAD, ITGB1, KIT, LMO1, SMAD3, OLR1, P2RX7, PSEN1, PTGER4, RAB27A, RAC2, RAG2, RELB, RPL22, S100A8, S100A9, SATB1, SELE, SELP, SELPLG, SLC11A1, SOD1, SOS1, SOS2, SRF, STAT6, STK10, STK11, ADAM17, ZEB1, TSC1, TNFRSF4, WNT1, FZD5, MADCAM1, FZD7, FZD8, FOXN1, STX11, SOX13, TNIP1, SEMA4D, SPINK5, BTN3A1 |
1166 | GO:0051897 | 0.00 | 2.67 | 16.46 | 27 | 44 | positive regulation of protein kinase B signaling | ANGPT1, AXL, CD28, HBEGF, F3, F7, F10, GAS6, GPX1, HCLS1, NRG1, IGF1, IGF1R, IGF2, IGFBP5, ILK, INS, PTK2, PTPRJ, CCL21, VEGFB, AKR1C3, CPNE1, SEMA5A, ITGB1BP1, BAG4, ARFGEF1 |
1167 | GO:0007169 | 0.00 | 2.67 | 42.29 | 70 | 117 | transmembrane receptor protein tyrosine kinase signaling pathway | ADRA2A, ADRB2, ALK, ANGPT2, APLP2, APP, AREG, BDKRB2, BLK, BTK, CD3E, CD4, CD7, CD8A, CD8B, CDH3, CSF1R, CSH1, CSPG4, DOK1, EPS8, EPS15, ESR1, EFEMP1, FGR, FRK, GFRA1, GFRA2, GH2, GHRH, GHRHR, GHSR, GRB7, HCK, HGF, IGF1, IGFBP2, IGFBP3, IGFBP5, IGFBP6, INSRR, ITGA1, NRTN, NTF3, NTF4, PDE6G, PDE6H, PIGR, PSEN1, PTPN6, PTPRR, SOX9, SRMS, STAT1, STAT5B, VIL1, WNT1, RAB7A, STAM, TNK1, DOK2, ANGPTL1, REPS2, EIF2AK3, GAB2, TNK2, STAM2, NRG3, ESM1, PTPRT |
1168 | GO:0002252 | 0.00 | 2.67 | 26.08 | 43 | 71 | immune effector process | ABL1, ACTB, ACTG1, CD3G, CDC42, CRP, CX3CR1, GPR183, PTK2B, FCGR1A, FCN2, GRB2, CFHR1, HSP90AA1, HSP90AB1, ITPR1, ITPR2, KRT1, LIMK1, CD180, CFP, PIK3CB, PRKCE, PSEN1, PTGER4, PTK2, RELB, TSC1, TYROBP, VTN, ATG5, TRIL, ABI1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, WASF2, VAV3, BAIAP2, ARPC1A |
1169 | GO:0070374 | 0.00 | 2.66 | 31.79 | 52 | 85 | positive regulation of ERK1 and ERK2 cascade | ABL1, ABL2, ANGPT1, ATP6AP1, BMP4, C3, CD36, CD44, CSF1R, CTGF, GPR183, EDNRA, ESR1, F2R, F2RL1, PTK2B, FGA, FGF4, FGFR3, FGFR4, FGG, FLT4, FSHR, GAS6, GCG, HMGCR, HTR2C, ICAM1, IL1A, IL1B, JUN, KDR, NTRK1, P2RY1, PRKCZ, PTEN, S100A7, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, XCL2, VEGFB, FGF23, RIPK2, NRP1, GPR55, RAPGEF2, ABCA7 |
1170 | GO:0040017 | 0.00 | 2.66 | 66.15 | 108 | 178 | positive regulation of locomotion | AAMP, ACVR1, ADRA2A, ALOX12, ANGPT1, ANXA3, BCL2, BMP4, CGA, COL1A1, CLDN7, CSF1R, CTSH, DAB2, DAPK3, DIAPH1, HBEGF, EPHA1, ETS1, F2R, F10, FBLN1, FGF7, FGR, FLT1, FLT4, FSHB, GPLD1, GRB7, HGF, HIF1A, ONECUT1, ICAM1, IFNG, IGF1, IGF1R, ILK, INS, INSL3, ITGA3, ITGA4, ITGA5, ITGAV, ITGB1, JUN, KIT, EPCAM, KITLG, P2RY2, P2RY6, PAWR, ENPP2, PFN1, PRKCE, RELN, PTAFR, PTGER4, PTK2, RDX, RPS6KB1, RREB1, SERPINB3, CCL20, CCL24, SDCBP, SELE, SELP, SEMA3F, SNAI1, SOX9, SPARC, TRIM21, TAC1, TMPRSS2, TRIP6, TWIST1, VIL1, VTN, WNT11, SEMA3B, MADCAM1, IKBKAP, NUMB, ADAM9, RAB11A, TNFRSF18, NRP2, ARHGEF7, ITGB1BP1, ONECUT2, BAG4, BCAR1, RAPGEF2, SEMA3E, HDAC4, HDAC6, PDCD6, SEMA3A, ATP8A1, RAPGEF3, TRIM38, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, BVES, CORO1A |
1171 | GO:0000186 | 0.00 | 2.66 | 50.87 | 83 | 136 | activation of MAPKK activity | ANGPT1, ARAF, BMP4, CALM1, CALM3, CAMK2A, CRKL, CSF2RB, HBEGF, DUSP5, ERBB2, EREG, ERCC6, F2R, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FLT1, FYN, GRB2, RAPGEF1, GRIN2A, GRM1, NRG1, IL2RA, KIT, KRAS, MARK3, MAP3K5, KITLG, MAP3K11, NTRK1, PEBP1, PPP5C, EIF2AK2, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTK2, PTPRA, RAF1, RASA2, SHC1, SOS1, UBB, FGF23, CUL3, PEA15, ADAM9, TAOK2, PSMF1, NRG2, RAPGEF2, PSMD6, RBX1, AKAP9, RASA4, PSME3, PSMD14, FRS3 |
1172 | GO:0001568 | 0.00 | 2.66 | 12.12 | 20 | 33 | blood vessel development | CDX2, CDX4, COL1A1, CRKL, DDIT3, DHCR7, GJA4, GPC3, RAPGEF1, LLGL2, PCSK5, PSEN1, SPINT1, WNT2, FOSL1, RECK, SERPINB7, ALDH1A2, SOCS3, TMED2 |
1173 | GO:0061061 | 0.00 | 2.66 | 43.33 | 71 | 117 | muscle structure development | ABL1, ACTG1, ACVR1, ADM, JAG1, AGTR2, BNIP2, BTG1, CACNB4, CASQ2, CD53, CDC42, CDH15, CDK9, CFL2, CHUK, CSRP2, CTH, CTNNA1, CTNNA2, DDIT3, DTYMK, EREG, FLNC, FLOT2, FLT3LG, KAT2A, HES1, HSPB2, IFRD1, IGF2, IGFBP3, IL18, ILK, ITGB1, KRAS, KRT19, MAP3K5, YBX1, NTF3, NTN3, PRKAR1A, RARA, RARB, RBM4, REST, SORT1, SLC9A1, SMARCA2, SMARCD3, SOX9, SRF, ZEB1, TMOD1, NR2C2, TSC1, WNT1, SORBS2, ITGA8, CAMK1, TNFSF14, DYRK1B, QKI, ATG5, GDF15, CXCL14, MAML1, RAMP2, ATG7, AFG3L2, GLMN |
1174 | GO:0001756 | 0.01 | 2.66 | 11.59 | 19 | 31 | somitogenesis | ATM, BMPR1A, CDX1, CDX2, EP300, KAT2A, FOXA2, SMAD3, MEOX2, OTX2, PAX3, PCDH8, PSEN1, KDM6A, XRCC2, RGS20, ZEB2, ABI1, DMRT2 |
1175 | GO:0046635 | 0.01 | 2.66 | 11.59 | 19 | 31 | positive regulation of alpha-beta T cell activation | ANXA1, CD3E, CD28, CD80, CD86, HLX, IFNG, IHH, IL12B, IL18, PRKCQ, PRKCZ, RARA, XCL1, TNFSF4, AP3B1, RIPK2, AP3D1, IKZF1 |
1176 | GO:1903513 | 0.01 | 2.66 | 11.59 | 19 | 31 | endoplasmic reticulum to cytosol transport | ATP1A2, CALM1, CALM3, CASQ1, CASQ2, CCR5, GSTM2, HRC, PDE4D, PLN, RYR1, RYR2, SEL1L, HSP90B1, GSTO1, AKAP6, TRDN, SEC61B, OS9 |
1177 | GO:1903793 | 0.01 | 2.66 | 11.59 | 19 | 31 | positive regulation of anion transport | ABAT, AVP, CCK, CFTR, CHRNB2, IL1B, NTSR1, P2RX4, P2RX7, P2RY2, PCP4, PRKCD, PTAFR, RAB3B, SLC34A1, SLC18A1, VAMP8, ABCA7, ATP8A1 |
1178 | GO:1901215 | 0.03 | 2.66 | 6.70 | 11 | 18 | negative regulation of neuron death | ATF4, CREB1, ESR1, IGF1, IL13, SERPINF1, PPP5C, STAT3, TRAF2, UCN, IKBKG |
1179 | GO:0042307 | 0.00 | 2.66 | 18.33 | 30 | 49 | positive regulation of protein import into nucleus | BMP4, BMP6, BMPR1A, BRCA1, CDH1, DAB2, EDA, HCLS1, HSP90AB1, IGF1, IL1B, IL12B, IL18, KPNA1, IPO5, SMAD3, PPP3R1, PRKCD, PRKCQ, SLC9A1, TRIP6, ZIC1, TNFSF14, HDAC3, SEMA5A, AKAP6, NUTF2, CHERP, RBCK1, EDAR |
1180 | GO:0048639 | 0.00 | 2.65 | 20.16 | 33 | 54 | positive regulation of developmental growth | ACACB, ADRB2, BMPR2, C3, CCNB1, EFNA5, GATA4, GATA6, GOLGA4, NRG1, HLX, IGF1, RBPJ, ILK, LIMK1, NTRK3, PARK2, PTGER4, RAG2, RPS6KB1, SRF, CDKL5, SYT1, SYT4, WNT2, RND2, RAB11A, NRP1, SEMA5A, AKAP6, RIMS2, IST1, SEMA4D |
1181 | GO:0097285 | 0.00 | 2.65 | 26.17 | 43 | 71 | cell-type specific apoptotic process | ABL1, ABL2, ALOX12, BMPR2, BTG1, CAMK2A, KRIT1, COL4A3, E2F2, EIF2S1, FAP, FGA, FGG, GNB1, GNGT1, NRG1, HMGCR, ICAM1, IGF1, IL12B, IL13, KDR, KRT18, SERPINE1, SERPINB13, RYR2, SORT1, SFRP4, SIX3, SOX9, TNFAIP3, PAX8, SCG2, CUL3, API5, AKR1C3, SEMA5A, STK17B, STK17A, BAG3, RAMP2, RAPGEF3, CAPN10 |
1182 | GO:0010959 | 0.00 | 2.65 | 36.08 | 59 | 97 | regulation of metal ion transport | ABL1, ATP2B2, BAX, BCL2, BMP4, TSPO, CACNA1B, CACNA2D1, CACNB3, CACNB4, CALM1, CALM3, CAMK2A, CASQ1, CD4, CD63, CRH, CYBA, DIAPH1, EDNRA, F2, F2R, GCG, FFAR1, GSTM2, HRC, ICAM1, IGF1, IL13, NTSR1, P2RX1, P2RX3, P2RX5, PAWR, PDE4B, PDE4D, PLN, PRKD1, PTPN6, RCVRN, RYR2, S100A1, XCL1, SEMG1, SLN, SNCA, SPINK1, STC1, TRPC1, TRPC3, TRPC4, UCN, WFS1, RGN, GSTO1, ATG5, TRDN, CREB3, CORO1A |
1183 | GO:0000003 | 0.00 | 2.65 | 115.28 | 187 | 312 | reproduction | ADM, ADRA2A, ADRB2, ALOX15B, AMBP, AMHR2, ANXA1, BIRC2, AREG, ARG1, ARHGDIB, ARNT, STS, ASCL2, CCND1, BMP6, BMPR1A, BMPR2, BOK, BSG, BYSL, CAPN5, CASP5, CCNE1, CCNF, CD38, CD44, CDC20, CDK2, CDX2, CDX4, CHAT, CKS2, CLU, COL9A3, COL16A1, COMT, CRH, CRHBP, CTNNA1, DBH, DCN, DHCR24, EPYC, DUSP1, EMP2, ERCC4, ESR1, ETS1, FANCA, ACSL4, FBLN1, FGF7, CENPI, NR5A1, GATA6, GHRHR, GHSR, GJB5, GNAQ, GNAS, GOLGA2, GPR3, GRB2, HSD17B10, HIF1A, HMGCS1, HES1, HSP90AB1, ICAM1, IDH1, IGF1R, IGF2, IGFBP2, IGFBP5, RBPJ, IL1A, IL10, IDO1, INHA, INSL4, INSRR, ITGA3, ITGA4, ITGB4, KDR, KISS1, KRT19, LLGL2, KITLG, CITED1, NTRK1, NUMA1, SERPINE1, PAM, PAPPA, PBX1, PCSK5, SERPINF1, SERPINB5, PRKACB, PRKAR1A, PSAP, PSG2, PSG3, PSG5, PSG6, PSG9, PSG11, PTAFR, PTGDR, PTGER4, PTGIS, PTHLH, PTK2, PTN, PTPRN, RAD1, PZP, RAB13, RAD21, RAD51, RAD51B, RAD51D, RLN1, RPL29, RRM1, RXRA, SALL1, SLIT3, SNAI1, SOX2, SP1, SPINT1, SRD5A1, SRY, ST14, STAR, STAT5B, STC1, SULT1E1, TOP2A, TOP2B, TRO, TRPM2, TUBG1, UBB, UCN, SCGB1A1, VCAM1, WNT2, WNT2B, XRCC2, CSDE1, FZD5, SMC1A, FZD4, RECK, AKR1C3, ADAM15, EIF2B2, EIF2B5, CDKL2, SOCS3, RQCD1, SMC3, EXO1, ZW10, SLIT2, HAND1, CUL7, SMC4, ACTR2, RAD50, FEM1B, IRX5, RAMP2, CITED2, SEMA3A, DMRT2, CORIN, STAG3, STAG2, TUBGCP2, PRDX3, TMED2, PIM2 |
1184 | GO:2000106 | 0.03 | 2.64 | 6.72 | 11 | 18 | regulation of leukocyte apoptotic process | ANXA1, BAX, BTK, CD3G, CDKN2A, IL10, P2RX7, PTEN, ADAM17, RAPGEF2, PDCD7 |
1185 | GO:0021872 | 0.00 | 2.64 | 13.46 | 22 | 36 | forebrain generation of neurons | ASCL1, CSF1R, DCX, GNAQ, HES1, OGDH, RAC1, RAC3, SALL1, SMARCC2, SOX1, SOX2, CNTN2, UBB, NUMB, NRP1, NUMBL, SLIT2, RAPGEF2, SEMA3A, ATG7, TBR1 |
1186 | GO:0032989 | 0.01 | 2.64 | 9.08 | 15 | 25 | cellular component morphogenesis | CASQ1, CASQ2, CAV3, CD9, CFL2, AGFG1, KRT19, PRKAR1A, TMF1, TMOD1, TNNT2, CSRP3, CFLAR, TBPL1, FIG4 |
1187 | GO:0061035 | 0.03 | 2.64 | 6.73 | 11 | 18 | regulation of cartilage development | ACVRL1, BMP1, BMP6, BMPR2, RUNX2, CTGF, HOXD11, IHH, SMAD1, SMAD3, CARM1 |
1188 | GO:0035821 | 0.00 | 2.64 | 30.67 | 50 | 82 | modification of morphology or physiology of other organism | ALB, APCS, BAD, BCL2L1, CAV2, CD4, CHD1, EP300, STOM, F2RL1, FBLN1, FCER2, IFNG, ITGAV, JUN, KPNA1, KPNA2, KPNA3, KPNA4, KPNA5, LTF, SMAD3, NTRK3, NUP88, NUP98, P2RX7, PARK2, SERPINB9, PPIB, EIF2AK2, RANBP2, REST, RXRA, S100A12, SMARCA4, SP1, TYMS, NUP214, AAAS, HMGA2, VAPB, RAB9A, NUP155, NUP93, BCL2L11, TNIP1, ATG7, RRAGA, NUP50, NUPL2 |
1189 | GO:0007616 | 0.04 | 2.64 | 6.73 | 11 | 18 | long-term memory | CAMK4, CTNS, GRIA1, NTF4, NTRK2, PRKCZ, RELN, RPS6KB1, SGK1, SRF, TAC1 |
1190 | GO:0008299 | 0.04 | 2.64 | 6.73 | 11 | 18 | isoprenoid biosynthetic process | ALDH1A3, DPAGT1, FDFT1, FDPS, HMGCR, HMGCS1, HMGCS2, RBP1, AKR1C3, ALDH1A2, DHRS9 |
1191 | GO:0015813 | 0.04 | 2.64 | 6.73 | 11 | 18 | L-glutamate transport | ATP1A2, KCNJ10, SEPT2, NTSR1, PSEN1, SLC1A3, SLC1A6, SLC1A7, SLC25A12, SLC25A13, ARL6IP5 |
1192 | GO:0019433 | 0.04 | 2.64 | 6.73 | 11 | 18 | triglyceride catabolic process | APOA1, APOH, CPS1, FABP2, FABP6, FABP7, GPLD1, LIPC, LIPE, PRKACB, PRKACG |
1193 | GO:0032459 | 0.04 | 2.64 | 6.73 | 11 | 18 | regulation of protein oligomerization | BAX, BID, CCK, CLU, CLDN7, IDE, INS, PEX14, PEX5, HRK, BCL2L11 |
1194 | GO:0033003 | 0.04 | 2.64 | 6.73 | 11 | 18 | regulation of mast cell activation | CNR1, CNR2, FCER1G, FGR, IL13, IL13RA2, PTPRE, RAC2, STXBP2, VAMP8, GAB2 |
1195 | GO:0034105 | 0.04 | 2.64 | 6.73 | 11 | 18 | positive regulation of tissue remodeling | ATP6AP1, BAX, CA2, ERG, FSHB, B4GALT1, HRG, IL12B, IL15, IL18, PTGER4 |
1196 | GO:0045747 | 0.04 | 2.64 | 6.73 | 11 | 18 | positive regulation of Notch signaling pathway | JAG1, ASCL1, EYA1, HES1, KIT, RFNG, SOX2, STAT3, WNT1, TP63, ITGB1BP1 |
1197 | GO:0045987 | 0.04 | 2.64 | 6.73 | 11 | 18 | positive regulation of smooth muscle contraction | ABAT, ADRA1B, CHRM3, CTTN, F2R, OXTR, PAWR, PTAFR, PTGS1, SRF, TACR3 |
1198 | GO:0050974 | 0.04 | 2.64 | 6.73 | 11 | 18 | detection of mechanical stimulus involved in sensory perception | ATP2B2, COL11A1, FYN, IGF1, KCNA1, KIT, NTRK1, PAWR, SLC12A2, SOX2, TRPA1 |
1199 | GO:0051204 | 0.04 | 2.64 | 6.73 | 11 | 18 | protein insertion into mitochondrial membrane | BAD, BAX, BCL2, BID, SFN, PPP3R1, MAPK8, YWHAZ, DYNLL1, BCL2L11, YWHAQ |
1200 | GO:0070423 | 0.04 | 2.64 | 6.73 | 11 | 18 | nucleotide-binding oligomerization domain containing signaling pathway | BIRC2, BIRC3, XIAP, CHUK, CYLD, IRAK1, IRAK2, TNFAIP3, UBB, IKBKG, RIPK2 |
1201 | GO:0042327 | 0.00 | 2.63 | 213.31 | 340 | 571 | positive regulation of phosphorylation | ABL1, ABL2, ACVR1, ACVR2A, ACVR2B, ACVRL1, ADCY3, ADCY5, ADCY6, ADCY9, ADRA1B, ADRA2A, ADRB2, AKT2, ALK, ANG, ANGPT1, ARAF, AREG, ATM, ATP6AP1, AVP, BAD, BAX, CCND1, BCL2, BMP1, BMP3, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, C3, CALM1, CALM3, CAMK2A, CAV2, CCK, CCNB1, CCNC, CCND3, CCNH, CCNT1, CCNT2, CD3E, CD4, CD80, CD36, CD44, CD81, CDC42, CDK9, CDKN1A, CENPE, CLU, CNTF, CREBL2, CRH, CRKL, CSF1R, CSF2RB, CSNK1D, CSPG4, CTF1, CTGF, DAB2, ACE, GADD45A, HBEGF, DUSP5, GPR183, LPAR1, EDN3, EDNRA, EEF1A2, EFNA1, EFNA5, EMP2, EPHA7, EPHA8, ERBB2, EREG, ERCC6, ERN1, ESR1, F2, F2R, F2RL1, ACSL1, PTK2B, FGA, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FGG, FGR, FLT1, FLT3, FLT3LG, FLT4, FPR1, FSHR, FYN, GAS6, GCG, GDF9, GFRA2, GNG3, GRB2, RAPGEF1, GRIN2A, GRM1, HCLS1, HGF, NRG1, UBE2K, HMGCR, HPX, HES1, HSP90AB1, HTR2C, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1R, IGF2, IGFBP3, IL1A, IL1B, IL2RA, IL12B, IL13, IL15, IL18, ILK, INHA, IRAK1, IRAK2, ISL1, ITGA1, ITGA5, ITGB1, JUN, KDR, KISS1, KIT, KRAS, LTF, MARK3, MAP3K5, KITLG, MAP3K11, NTF3, NTRK1, NTRK2, NTRK3, TNFRSF11B, P2RY1, PEBP1, PDE6G, PDE6H, ENPP2, PFKFB1, PFKFB2, PFN2, PIK3CB, PIM1, PPP5C, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCE, PRKD1, PRKCZ, EIF2AK2, RELN, PSAP, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTGER4, PTK2, PTPN1, PTPRA, RAC1, RAF1, RAP2A, RAP2B, RASA2, RPS3, RYK, S100A7, S100A12, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SDCBP, SHC1, STIL, SLC11A1, SNCA, SOD1, SOS1, SOX2, SOX9, SPN, STK10, STK11, XCL2, ADAM17, TNFRSF1A, TNFRSF1B, TP73, TPD52L1, TRAF2, TTK, TNFRSF4, UBB, UCN, VEGFB, VEGFC, VTN, WNT1, WNT11, ZNF16, FZD5, ARHGEF5, FGF23, CDK2AP1, FZD4, FZD7, FZD8, BCAR3, CUL3, OGT, IKBKG, CAMK1, MAPKAPK5, PDE5A, PEA15, RIPK1, ADAM9, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10B, TNFRSF10A, NRP1, HDAC3, RPS6KA4, TNFSF18, UNC119, LATS1, ARHGEF2, VAPB, CRLF1, ITGB1BP1, GPR55, S1PR2, TAOK2, PSMF1, GDF15, BAG4, NRG2, TRAF4, RAPGEF2, SLK, ATG13, RB1CC1, ZEB2, PSMD6, OXSR1, TNFSF15, RBX1, ABI1, TOM1L1, RAD50, AKAP9, RASA4, SORBS3, TNK2, PSME3, PSMD14, ABCA7, RAPGEF3, VAV3, MAD2L2, STK25, SEMA4D, ARL6IP5, NRG3, FRS3, MALT1, JTB, COPS8, IL24, GLMN, MAP4K5, CHEK2, FZD10 |
1202 | GO:0006366 | 0.01 | 2.63 | 11.46 | 19 | 32 | transcription from RNA polymerase II promoter | BTF3, ERCC6, HIVEP2, HLF, SNAPC2, SNAPC3, TMF1, ZNF141, PIR, RNGTT, TRIM24, TSC22D1, TAF1C, TAF1A, DDX21, TRIP11, TBPL1, ZNF516, HSF2BP |
1203 | GO:0006518 | 0.00 | 2.63 | 24.48 | 40 | 66 | peptide metabolic process | AEBP1, BGLAP, CGA, CLU, TPP1, CLN5, CPD, CTNS, CTSH, CTSZ, ACE, DPEP1, F2, F7, F10, FSHB, GAS6, GPX1, GSTM1, GSTM2, GSTZ1, IDE, IDH1, LTA4H, PCSK6, PAM, PROC, PSEN1, RNPEP, SOD1, TSHB, PICALM, BECN1, PROZ, PCSK7, GSTO1, ATP6AP2, ABCA7, CORIN, ADAMTS13 |
1204 | GO:0006635 | 0.00 | 2.63 | 15.33 | 25 | 41 | fatty acid beta-oxidation | ACAA1, ACACB, ACADL, ACADM, ACADS, ACADSB, ACADVL, AKT2, ABCD1, CNR1, CPT1B, CPT2, CRAT, DECR1, ECH1, IVD, PEX7, ABCD3, TWIST1, ACOX2, ACOX3, ACOT8, ECI2, SLC25A17, SLC27A2 |
1205 | GO:0042475 | 0.00 | 2.63 | 15.33 | 25 | 41 | odontogenesis of dentin-containing tooth | ACVR2B, ADM, AMBN, BAX, BMP4, BMPR1A, BSG, CA2, RUNX2, CHUK, ATF2, CTNNA1, EDA, FGF4, ITGB4, LAMA5, TNFRSF11B, SCN5A, SCN10A, SLC34A1, TP63, HAND1, KLK4, BCL2L11, EDAR |
1206 | GO:0042594 | 0.02 | 2.63 | 8.57 | 14 | 23 | response to starvation | ACADS, ADM, ADSL, ALDOB, CPS1, DDIT3, GCG, GCGR, HMGCL, HMGCS2, OXCT1, PFKFB1, SSTR2, ZFP36 |
1207 | GO:0044409 | 0.00 | 2.62 | 25.81 | 42 | 69 | entry into host | APCS, AXL, CAV2, CD4, CD80, CD86, SCARB2, CD81, CCR5, CR2, CXADR, DPP4, EPS15, GAS6, GYPA, ICAM1, IDE, IFNA2, ITGA5, ITGAV, ITGB1, KPNA3, CD46, PVR, SERPINB3, SELPLG, SLC10A1, TRIM21, DYNLT1, TMPRSS2, TNFRSF4, TYRO3, UVRAG, TRIM25, VAMP8, CLDN1, IFITM3, TRIM38, SIVA1, IFITM2, WWP1, WWP2 |
1208 | GO:0051806 | 0.00 | 2.62 | 25.81 | 42 | 69 | entry into cell of other organism involved in symbiotic interaction | APCS, AXL, CAV2, CD4, CD80, CD86, SCARB2, CD81, CCR5, CR2, CXADR, DPP4, EPS15, GAS6, GYPA, ICAM1, IDE, IFNA2, ITGA5, ITGAV, ITGB1, KPNA3, CD46, PVR, SERPINB3, SELPLG, SLC10A1, TRIM21, DYNLT1, TMPRSS2, TNFRSF4, TYRO3, UVRAG, TRIM25, VAMP8, CLDN1, IFITM3, TRIM38, SIVA1, IFITM2, WWP1, WWP2 |
1209 | GO:0052192 | 0.00 | 2.62 | 25.81 | 42 | 69 | movement in environment of other organism involved in symbiotic interaction | APCS, AXL, CAV2, CD4, CD80, CD86, SCARB2, CD81, CCR5, CR2, CXADR, DPP4, EPS15, GAS6, GYPA, ICAM1, IDE, IFNA2, ITGA5, ITGAV, ITGB1, KPNA3, CD46, PVR, SERPINB3, SELPLG, SLC10A1, TRIM21, DYNLT1, TMPRSS2, TNFRSF4, TYRO3, UVRAG, TRIM25, VAMP8, CLDN1, IFITM3, TRIM38, SIVA1, IFITM2, WWP1, WWP2 |
1210 | GO:0030901 | 0.02 | 2.62 | 8.58 | 14 | 23 | midbrain development | APLP2, PHOX2A, EN1, KAT2A, HES1, SMAD1, SMAD9, OTX1, OTX2, RYK, TAL2, WNT1, WNT2, FZD6 |
1211 | GO:0043271 | 0.00 | 2.62 | 19.04 | 31 | 51 | negative regulation of ion transport | ABAT, ADRA2A, AGTR2, AKT2, ATP1A2, BCL2, CALM1, CALM3, CNR1, DRD3, ACSL4, GRK6, GSTM2, ICAM1, IL1B, NTSR1, PAWR, PLN, PRKCE, SEMG1, SFRP4, SLC18A1, SLN, SNCA, SPINK1, STC1, TWIST1, SLC9A3R1, GSTO1, TRDN, YWHAQ |
1212 | GO:0098754 | 0.00 | 2.62 | 17.20 | 28 | 46 | detoxification | ALB, CAT, CD36, DHFR, FANCC, GPX1, GPX2, GPX3, GPX7, GSTM1, GSTM2, GSTZ1, HBA2, HP, PRDX1, PTGS1, S100A9, SEPW1, SOD1, SOD2, PXDN, EPX, RGN, GSTO1, PRDX6, FBLN5, PRDX4, PRDX3 |
1213 | GO:0043207 | 0.00 | 2.61 | 181.77 | 290 | 486 | response to external biotic stimulus | ABCA1, ABL1, ADAR, ADARB1, ADH5, ADM, ALAD, ANG, ANXA3, ANXA5, BIRC2, BIRC3, APP, KLK3, ARF1, ARG1, ASS1, ATP4B, AXL, BAD, BCL2, BCL2L1, BCL3, BCR, PRDM1, BMP6, BNIP3, BNIP3L, BPI, BST2, BYSL, TSPO, CASP1, CASP9, CD4, CD6, CD8A, CD8B, CD28, CD80, CD86, TNFRSF8, TNFSF8, CD36, CD37, ENTPD2, CDK6, CEBPE, CHIT1, CHUK, AP1S1, AP2S1, CLU, CCR5, CNP, CNR1, CNR2, COMT, COX8A, CLDN7, CPS1, CRP, CX3CR1, CXADR, CYBA, DCN, DDX1, DMBT1, DNMT1, EDNRA, EIF2S1, STOM, F2R, F2RL1, F3, FAU, FCER1G, FCGR3B, FCN2, FGA, FGF7, FGR, FYN, SLC37A4, GABRA5, GBP3, GFI1, GPX1, CXCL1, CXCL3, GTF2F1, HCK, HIF1A, HMGCS2, HMGA1, HP, HRG, HSPB1, ICAM1, IFI16, IFIT1, IFIT3, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNGR1, IFNW1, IGF1, RBPJ, IL1B, IL2RA, IL10, IL10RA, IL12B, IL12RB2, IL13, IL15, IL17A, IL18, ILF3, IDO1, IRAK1, IRAK2, IRF1, IRF5, ISG20, JUN, JUND, KCNJ8, KCNQ1, LTF, CD180, SMAD3, MDH1, CITED1, NTHL1, OAS2, OAS3, TNFRSF11B, P2RX7, P2RY2, SERPINE1, PAWR, PCBP2, PDE4B, PDE4D, PDK4, PENK, PEX13, PF4, PF4V1, CFP, PGC, SERPINB9, SERPINB10, PPM1B, PRG2, PRKCD, PRKCE, MAPK8, EIF2AK2, PSMA2, PTAFR, PTGER1, PTGER2, PTGER4, RAB1A, RAC1, RARA, UPF1, ABCE1, RPL39, RPS6KB1, S100A7, S100A8, S100A9, S100A12, SCN1A, CCL20, CCL22, CXCL6, CXCL5, XCL1, SEC14L1, SELE, SELP, SEMG1, SFTPD, SLC1A3, SLC11A1, SLPI, SNCA, SNRPD1, SPARC, SPN, STAR, STAT1, STAT2, STAT5B, ABCC8, TAC1, ADAM17, TMF1, TNFAIP3, TNFRSF1A, TNFRSF1B, TPT1, TNFSF4, TNFRSF4, SCGB1A1, VCAM1, VIL1, VIP, TRIM25, ZNF189, FZD5, FOSL1, HMGA2, CHAF1B, EPX, HIST1H2BG, HIST2H2BE, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, OGT, PPM1D, PARG, IKBKG, BECN1, URI1, ADAM9, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, BANF1, AP1S2, AP1M1, HIST1H3F, HIST1H2BJ, SOCS3, DDX21, IL27RA, CHST3, ATG5, ADAMTS4, LITAF, CTR9, NUP93, PHYHIP, IST1, ELMO1, NR1H4, FGFBP1, BCL2L11, AP1M2, ABCC9, IL18BP, TRIB1, TRIM22, IFITM3, SPON2, BAIAP2, TRIM38, CREB3, ATG7, IFI44, CXCL13, IFITM2, IVNS1ABP, TRAF3IP2, GJB6, MALT1, PRDX3, SERINC3, IFI44L, SPINK5, IL24, PIM2, ADAMTS5, CD160 |
1214 | GO:0030307 | 0.00 | 2.61 | 29.55 | 48 | 79 | positive regulation of cell growth | ADAM10, ALOX12, AVP, BCL2, BMPR2, CD38, CDC42, CSNK2A1, CYBA, HBEGF, EFNA5, ERBB2, EXTL3, F2, ACSL4, PTK2B, GOLGA4, SFN, UTS2R, HIST1H1B, NRG1, IGF1, ILK, INS, LIMK1, NTRK3, PARK2, RPS6KA1, S100A8, S100A9, SDCBP, SGK1, SLC9A1, SRF, CDKL5, SUPV3L1, SYT1, SYT4, ADAM17, UCN, RND2, RAB11A, NRP1, SEMA5A, AKAP6, RIMS2, IST1, SEMA4D |
1215 | GO:0002448 | 0.02 | 2.61 | 8.60 | 14 | 23 | mast cell mediated immunity | FCER1G, FGR, IL13, IL13RA2, KIT, SERPINB9, RAC2, S100A13, STXBP2, LAT2, VAMP8, GAB2, SPON2, CPLX2 |
1216 | GO:0035176 | 0.02 | 2.61 | 8.60 | 14 | 23 | social behavior | ANXA7, AVP, BBS4, CHRNB2, DRD3, GRID1, IL1B, KRAS, OXTR, PTEN, UCN, NRXN3, NRXN1, NRXN2 |
1217 | GO:0045104 | 0.02 | 2.61 | 8.60 | 14 | 23 | intermediate filament cytoskeleton organization | DST, DSP, GFAP, AGFG1, KRT6A, KRT9, KRT18, ATXN3, PRPH, RAF1, SOD1, VIM, BFSP2, INA |
1218 | GO:0048265 | 0.02 | 2.61 | 8.60 | 14 | 23 | response to pain | TSPO, CACNA1A, CACNA1B, COMT, CRH, DBH, GJA4, NTRK1, P2RX3, RELN, TAC1, UCN, TRPV1, TRPA1 |
1219 | GO:2000107 | 0.02 | 2.61 | 8.60 | 14 | 23 | negative regulation of leukocyte apoptotic process | AXL, BMP4, TSC22D3, FCER1G, GAS6, HCLS1, HIF1A, IDO1, KITLG, PRKCQ, RAG1, CCL21, ST6GAL1, AURKB |
1220 | GO:0007411 | 0.00 | 2.61 | 108.07 | 174 | 290 | axon guidance | ABL1, ABL2, ACTB, ACTG1, ADAM10, ANGPT1, APP, ARAF, ATOH1, CACNB3, CACNB4, CALM1, CALM3, CAMK2A, CD72, CDC42, AP2S1, CLTA, COL3A1, COL4A3, COL4A5, COL5A2, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2RB, CSNK2A1, CSNK2A2, DCC, DCX, DLG3, DLX5, DNM1, DPYSL3, HBEGF, DUSP5, EFNA1, EFNA3, EFNA4, EFNB1, EPHA2, EPHA1, EPHA5, EPHA8, EPHB2, EREG, EXT1, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FYN, GFRA1, GRB2, GRIN2A, ARHGAP35, NRG1, HSPA8, HSP90AA1, HSP90AB1, IL2RA, ITGA1, ITGA5, ITGA9, ITGAV, ITGB1, KIF5A, KIT, KRAS, ABLIM1, LIMK1, MARK3, KITLG, NRTN, NTF3, NTRK1, NTN3, OTX2, PEBP1, PPP5C, PRKCQ, PSPN, RELN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTK2, PTPRA, RAC1, RAC2, RAF1, RASA2, RPS6KA1, RYK, SCN5A, SDC2, SDCBP, SHC1, SIAH1, SOS1, SOS2, CNTN2, TNR, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, FGF23, CUL3, CNTNAP1, KLF7, UNC5C, NUMB, PEA15, ARHGEF7, RPS6KA4, KALRN, NRXN3, NRXN1, PSMF1, NRG2, FEZ2, RAPGEF2, ARHGEF11, FARP2, PSMD6, RBX1, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, PSME3, PSMD14, SPON2, VAV3, CAP1, ARPC1A, DPYSL4, CHL1, FRS3, VAX1 |
1221 | GO:0072593 | 0.00 | 2.61 | 15.94 | 26 | 43 | reactive oxygen species metabolic process | ALOX12, AOX1, ARG2, CALM1, CALM3, CAT, CPS1, CTGF, CYBB, DRD5, FANCC, GPX1, GPX3, HBA2, P2RX7, PRDX1, PDK4, SFTPD, SOD2, VAV1, PXDN, EPX, PRDX6, PRG3, PRDX4, PRDX3 |
1222 | GO:0001101 | 0.00 | 2.61 | 27.00 | 44 | 73 | response to acid chemical | ABCA1, ABL2, BMP4, BMP6, CD9, CD38, AKR1C4, ATF2, CTSH, BRINP1, DHFR, DUSP1, PHC1, PTK2B, HIF1A, HLCS, IGFBP2, KRT13, NTRK1, NTRK3, OTC, SERPINF1, RARA, RXRA, SHMT1, SIPA1, SOX2, SOX9, SP100, SPARC, SCGB1A1, WNT2, WNT11, ZNF35, SLC14A2, SLC10A3, FZD4, FZD7, OGT, ALDH1A2, KLF4, SLC22A6, TRIM16, FZD10 |
1223 | GO:0071363 | 0.00 | 2.60 | 34.76 | 57 | 96 | cellular response to growth factor stimulus | ANGPT2, ARHGAP4, BGLAP, BYSL, CAT, AP2S1, CLU, CLTA, CRKL, DTYMK, DUSP4, ELK1, FGD1, GAS6, HGF, HTR3A, IRAK1, NTRK3, OMG, PAX9, PCSK5, PPP2R5D, PRKCI, MAPK8, PTN, RAC1, RALA, RAP1GAP, RIT1, RPS6KA1, RPS6KB1, SOS2, SPARC, SRD5A1, STAT3, STAT5B, TNFRSF1B, TWIST1, VIL1, BECN1, URI1, RIPK1, RIPK2, HDAC3, ARHGEF7, KALRN, ARHGEF1, ARHGEF2, KLF4, ARHGEF6, BAG4, BCAR1, ARHGEF11, ARHGEF17, BCL2L11, VAV3, AKAP13 |
1224 | GO:0050900 | 0.00 | 2.60 | 45.00 | 73 | 121 | leukocyte migration | ANGPT1, ANGPT2, ANXA1, ATP1B3, BCR, BSG, CD44, CD58, CDC42, CCR5, COL1A1, CX3CR1, CXADR, DBH, ECM1, S1PR1, EPS8, F2, FCER1G, FLT1, FYN, B4GALT1, GPR15, GRB2, GRB7, HCK, HRH1, IFNG, IL10, ITGA1, ITGA3, ITGA5, ITGA9, ITGAM, ITGAV, ITGAX, ITGB1, KIT, KRAS, OLR1, PDE4B, PDE4D, PIK3CB, PROC, PTPN6, RPS19, S100A8, S100A9, S100A12, CCL22, CCL25, SELL, SELPLG, SFTPD, SHC1, SLC16A1, SOS1, SPN, STAT5B, STK10, XCL2, VAV1, VCAM1, SCG2, ARHGEF5, SLC7A5, EPX, DOK2, SLIT2, VAV3, PROCR, SLC7A9, CORO1A |
1225 | GO:0043266 | 0.01 | 2.60 | 10.45 | 17 | 28 | regulation of potassium ion transport | ADRA2A, ADRB2, ATP1B3, DNM2, DPP6, EDN3, KCNC1, KCNC2, KCNJ1, KCNJ2, KCNS2, ABCC8, AKAP7, AKAP6, AKAP9, RAPGEF3, WWP2 |
1226 | GO:0048524 | 0.00 | 2.60 | 20.94 | 34 | 56 | positive regulation of viral process | ADAR, ADARB1, CAV2, CCNH, CCNT1, CD28, CDK9, CHD1, EP300, STOM, ERCC3, NR5A2, GTF2F1, IFIT1, JUN, PPIB, PPID, SMARCA4, SP1, SRPK2, TRIM21, SSRP1, STAU1, SUPT4H1, TMPRSS2, TOP2A, TSG101, RAB7A, CTDP1, VAPB, PPIE, PPIH, TRIM38, SUPT16H |
1227 | GO:0051704 | 0.00 | 2.60 | 113.75 | 186 | 323 | multi-organism process | ABCA1, ABL1, ADH5, ALAD, ANXA3, ANXA5, ANXA7, BIRC2, KLK3, ASS1, ATP4B, BCL3, BCR, BMP6, BPI, TSPO, CASP1, CASP9, CD6, CD8A, TNFRSF8, TNFSF8, CD37, ENTPD2, CDK6, CEBPE, CHIT1, CHRNB2, CHUK, CLU, CNP, CNR2, COX8A, CLDN7, CPS1, CRP, CYBA, DCN, DDX1, DNMT1, DRD3, EIF2S1, F2R, F3, FCER1G, FCGR3B, FCN2, FGA, FGF7, FGR, SLC37A4, GABRA5, GBP3, GLS, GRID1, CXCL1, CXCL3, HMGCS2, HP, HRG, HSPB1, IFIT3, IFNA5, IFNA13, IFNA17, IFNA21, IFNGR1, IFNW1, RBPJ, IL10RA, IL12RB2, IL13, IL15, IL17A, IL18, IRAK1, IRAK2, IRF1, IRF5, JUND, KCNJ8, KCNQ1, KRAS, CD180, MDH1, CITED1, NTHL1, OAS2, TNFRSF11B, SERPINE1, PAWR, PDE4B, PDE4D, PDK4, PENK, PEX13, PF4, PF4V1, CFP, PGC, SERPINB10, PRG2, PRKCD, PRKCE, MAPK8, PTGER1, PTGER2, UPF1, S100A7, S100A8, S100A9, SCN1A, CCL20, CCL22, CXCL6, CXCL5, XCL1, SELE, SELP, SFTPD, SLC1A3, SLC11A1, SNCA, SNRPD1, SPARC, SPN, STAR, ABCC8, ADAM17, TNFRSF1B, TPT1, TNFSF4, VIL1, ZNF189, FZD5, CHAF1B, EPX, HIST1H2BG, HIST2H2BE, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, OGT, PPM1D, PARG, URI1, ADAM9, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, HIST1H3F, HIST1H2BJ, SOCS3, DDX21, NRXN3, NRXN1, NRXN2, IL27RA, CHST3, ADAMTS4, LITAF, CTR9, PHYHIP, NR1H4, FGFBP1, ABCC9, IL18BP, SPON2, BAIAP2, IFI44, CXCL13, TRAF3IP2, GJB6, MALT1, SERINC3, IFI44L, IL24, PIM2, ADAMTS5, CD160 |
1228 | GO:0048754 | 0.01 | 2.60 | 12.30 | 20 | 33 | branching morphogenesis of an epithelial tube | ACVR1, BAX, CTSH, CTSZ, EDNRA, B4GALT1, HHEX, FOXA2, IGF1, IHH, KDR, KRAS, SOX2, SRF, WNT2, NRP1, SEMA5A, SLIT2, SEMA3E, SPRY1 |
1229 | GO:0001754 | 0.01 | 2.59 | 10.47 | 17 | 28 | eye photoreceptor cell differentiation | BBS4, PRDM1, GNAT1, GNAT2, GNGT1, IHH, NRL, NTRK2, OTX2, PRKCI, PTN, RPGR, SOX9, STAT3, TULP1, SLC4A7, NR2E3 |
1230 | GO:1902110 | 0.01 | 2.59 | 10.47 | 17 | 28 | positive regulation of mitochondrial membrane permeability involved in apoptotic process | BAD, BAX, BCL2, BID, BNIP3, BNIP3L, ATF2, EYA2, SFN, PPP3R1, MAPK8, YWHAZ, DYNLL1, BCL2L11, ACAA2, SIVA1, YWHAQ |
1231 | GO:0002755 | 0.01 | 2.58 | 12.34 | 20 | 33 | MyD88-dependent toll-like receptor signaling pathway | BTK, CD36, CHUK, CREB1, ATF2, DUSP4, ELK1, IRAK1, IRAK2, IRF1, JUN, PPP2R5D, MAPK8, RPS6KA1, SKP1, UBB, CUL1, IKBKG, RIPK2, TNIP1 |
1232 | GO:0010803 | 0.01 | 2.58 | 12.34 | 20 | 33 | regulation of tumor necrosis factor-mediated signaling pathway | BIRC2, BIRC3, APOA1, CHUK, CYLD, F2RL1, GAS6, PARK2, TNFAIP3, TNFRSF1A, TRAF1, TRAF2, UBB, IKBKG, TRADD, RIPK1, TAX1BP1, CPNE1, TRAIP, RBCK1 |
1233 | GO:0071300 | 0.01 | 2.58 | 12.34 | 20 | 33 | cellular response to retinoic acid | ABCA1, ABL2, COL1A1, BRINP1, PHC1, PTK2B, KRT13, NTRK3, SERPINF1, RARA, SOX9, WNT2, WNT11, ZNF35, FZD4, FZD7, OGT, ALDH1A2, KLF4, FZD10 |
1234 | GO:0046939 | 0.00 | 2.57 | 17.95 | 29 | 48 | nucleotide phosphorylation | AK1, AK2, AK4, ALDOB, ALDOC, ARNT, DTYMK, ENO2, ENO3, GAPDH, GPD1, HIF1A, IGF1, INS, LDHA, OGDH, P2RX7, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PGM1, PPP2R5D, PRKAA1, PRKAG1, STAT3, OGT, HDAC4 |
1235 | GO:0009179 | 0.00 | 2.57 | 19.82 | 32 | 53 | purine ribonucleoside diphosphate metabolic process | AK1, AK2, AK4, ALDOB, ALDOC, ARNT, BAD, ENTPD2, DLG2, DLG3, ENO2, ENO3, GAPDH, GPD1, HIF1A, IGF1, INS, LDHA, OGDH, P2RX7, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PGM1, PPP2R5D, PRKAA1, PRKAG1, STAT3, OGT, HDAC4 |
1236 | GO:0072091 | 0.00 | 2.57 | 19.82 | 32 | 53 | regulation of stem cell proliferation | BMP4, BMPR1A, CTNNA1, CX3CR1, ACE, FBLN1, HIF1A, IHH, KDR, EPCAM, KITLG, OVOL1, PRRX1, EIF2AK2, PTN, CX3CL1, SIX1, SIX3, SMARCD3, SOX2, SOX9, SOX10, SOX11, STAT1, ZEB1, VEGFC, WNT2, WNT11, HMGA2, TP63, CHRD, VAX1 |
1237 | GO:0034109 | 0.00 | 2.56 | 41.47 | 67 | 112 | homotypic cell-cell adhesion | ABL1, ABL2, BAX, BCL2, BCL3, ZFP36L2, CAMK4, RUNX2, CCND3, CD7, CD8A, CD8B, TNFSF8, CD151, CDK6, CLC, CTPS1, CXADR, DSC2, DSP, F2RL1, FCER1G, FLT3, ICAM1, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, INS, ITGAD, KIT, LMO1, SMAD3, P2RX7, PSEN1, PTGER4, RAB27A, RAC2, RAG2, RELB, RPL22, S100A8, S100A9, SATB1, SLC11A1, SOD1, SOS1, SOS2, SRF, STAT6, STK10, STK11, ADAM17, ZEB1, TSC1, TNFRSF4, WNT1, FZD5, FZD7, FZD8, FOXN1, STX11, SOX13, SEMA4D, SPINK5, BTN3A1 |
1238 | GO:0051241 | 0.00 | 2.56 | 93.18 | 150 | 254 | negative regulation of multicellular organismal process | ABAT, ADCY6, ADRA2A, JAG1, ALOX12, ANXA5, APP, ARF6, ARHGAP4, ARHGDIB, ASCL1, ASCL2, ATP2A1, AVPR2, BBS2, BCR, BMPR1A, BRCA2, SERPING1, CD86, CD38, CHAD, CNTF, COL3A1, COL5A2, COMT, CRH, CRHBP, CRY1, CTNNA1, CXADR, DCC, DDIT3, DDX6, DPYSL3, DRD3, TSC22D3, LPAR1, EFNA1, EIF4E, EPHA7, ETV4, F2, FAP, FGA, FGF3, FGFR3, FGG, NR5A1, GAK, GDI1, GFAP, GFI1, GNAS, GP1BA, NRG1, FOXA2, IAPP, IFRD1, IGF1, IL1B, ISL1, ITGB1, KCNK2, KLKB1, KNG1, KRT1, LRPAP1, SMAD7, CIITA, NTRK3, OMG, TNFRSF11B, OXTR, P2RX7, SERPINB2, PBX1, PCM1, PDE4B, PRKACB, PRKCD, PROC, PSEN1, PTK2, RAP1GAP, REST, RNF6, RPS19, S100B, SALL1, SEMA3F, SFRP5, SRSF6, SIX1, SIX3, SNAI1, SOD1, SOX3, SOX11, SPOCK1, SRF, STAT3, STK11, CNTN2, DYNLT1, TNNT1, TNR, TP73, TTC3, TULP3, UCN, USF1, VIM, VTN, PAX8, SEMA3B, FZD7, TP63, NRP1, HDAC3, PHOX2B, SEMA5A, USP2, RGN, ARHGEF1, CBFA2T2, ARHGEF2, BAG5, AATK, RAPGEF2, KIAA0319, RNF10, CALCRL, OLIG2, HMG20A, RAPGEF3, MAD2L2, CARM1, SEMA6C, SEMA6B, SEMA4F, SEMA4B, PROCR, PRDX4, NRG3, RAI1, USP19, VAX1, STMN2, CIT |
1239 | GO:0002819 | 0.00 | 2.56 | 23.56 | 38 | 63 | regulation of adaptive immune response | ANXA1, BTK, C3, CD4, CD28, CD80, CLC, FCER1G, FCER2, HLX, HPX, IFNA2, IFNG, IL1B, IL10, IL12B, IRF1, P2RX7, PRKCQ, PRKCZ, PTPN6, PVR, XCL1, SLC11A1, SPN, STAT6, TNFAIP3, TRAF2, TNFSF4, UNG, WHSC1, FZD5, RIPK2, TNFSF18, IL1RL1, IL27RA, TNFSF13B, MALT1 |
1240 | GO:0019058 | 0.00 | 2.56 | 41.50 | 67 | 112 | viral life cycle | DDX6, FAU, HSP90AB1, KPNA1, KPNA2, KPNA4, KPNA5, RPL10A, NUP88, NUP98, CHMP1A, PCSK5, RAB1A, RAN, RANBP2, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, UBB, USF1, RAB7A, NUP214, AAAS, RPL14, RPL23, ATG5, NUP155, NUP93, IST1, PDCD6IP, ATG7, CXCR6, NUP50, NUPL2, RPL35 |
1241 | GO:0031668 | 0.00 | 2.56 | 42.26 | 68 | 113 | cellular response to extracellular stimulus | ALB, ALDOB, ASGR1, ATF4, ATP2B1, AXL, BCL2, BGLAP, BMPR2, CBS, CCNE1, CDKN1A, COL1A1, COMT, CTSV, CYP24A1, DSC2, EIF2S1, GAS6, GLUL, FOXA2, HSPA8, ICAM1, IFI16, IL15, ITGB1, JUN, LDHA, P2RX7, PAWR, PCK1, CHMP1A, PDK4, PENK, PIK3C3, PIM1, PRKAA1, EIF2AK2, PTN, RHAG, RHCE, RHD, SIPA1, SLC2A1, SRD5A1, SREBF1, SRF, KLF10, TSC1, UPP1, USF1, WNT2B, FOSL1, FGF23, PPM1D, AKR1C3, BECN1, TRIM24, AIFM1, EIF2AK3, PICK1, ATG5, ADAMTS1, ATG13, NR1H4, ATG7, GAS2L1, RRAGA |
1242 | GO:0007596 | 0.00 | 2.56 | 60.71 | 98 | 165 | blood coagulation | ABL1, ANGPT1, ANGPT2, ATP1B3, ATP2A1, ATP2B1, ATP2B2, ATP2B3, BSG, C3, CAPZA1, CAPZB, ENTPD1, CD44, CD58, CD59, CDC42, CDK2, CENPE, CXADR, F2RL1, FGR, GATA4, GATA6, GGCX, GRB7, GUCY1B3, HBD, HBE1, HBG1, SERPIND1, FOXA2, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IRF1, IRF2, ITGA1, ITGA3, ITGA4, ITGA5, ITGAM, ITGAV, ITGAX, ITGB1, KIF5A, KLC1, KRAS, LMAN1, OLR1, SERPINA5, PDE3A, PDE3B, PDE1B, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, RAB5A, RAB27A, RAD51C, RAD51B, SELE, SELL, SELPLG, SLC8A3, SLC16A1, SPN, WEE1, SLC7A5, AKAP1, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, AP3B1, PDE5A, PROZ, HIST1H3F, DOK2, PAPSS2, KIF3B, SH2B3, KCNMB2, HMG20B, PROCR, SH2B2, PDE10A, KIF2C, KIF3A, SLC7A9, HPS5 |
1243 | GO:0000082 | 0.00 | 2.55 | 24.16 | 39 | 65 | G1/S transition of mitotic cell cycle | ACVR1, ANXA1, BCAT1, BID, CAMK2A, CCNB1, CCNH, CDC25A, CDK3, CDK4, CDK6, CDKN2A, CKS1B, EIF4E, EIF4EBP1, ITGB1, ORC2, ORC4, ORC5, PIM1, PPP6C, PRIM2, PTPN6, RDX, RPA3, RPS6KB1, SKP1, ADAM17, UBE2E2, WEE1, CUL4A, CUL3, CUL2, CUL1, LATS1, CCNE2, PDPN, DBF4, PIM2 |
1244 | GO:0006952 | 0.00 | 2.55 | 26.78 | 44 | 76 | defense response | ADM, ANXA3, KLK3, BCL3, BNIP3, BNIP3L, BPI, CCK, CD8A, TNFSF8, CEBPE, CXADR, DBI, DPP4, EIF4E, EIF4G1, GBP3, HRG, HTR2C, IFNW1, ILF3, KCNJ8, KCNN4, P2RY11, PRG2, PSG3, RAB1A, RNASE6, RPS6KB1, SEMG1, ADAM17, TMF1, TPSAB1, EPX, FOXN1, IL32, SOCS6, IL27RA, ADAMTS4, ABCC9, DEAF1, ATG7, IFI44L, ADAMTS5 |
1245 | GO:0045666 | 0.00 | 2.55 | 14.85 | 24 | 40 | positive regulation of neuron differentiation | ASCL1, ATOH1, BCL2, BMP6, CRX, BRINP1, DNMT3B, EIF4G1, ETV5, FOXA2, HOXD3, IFNG, NRCAM, RARA, RARB, SALL1, SOX2, SOX11, ZEB1, WNT2, RNF112, CPNE1, PHOX2B, HMG20B |
1246 | GO:0090130 | 0.00 | 2.55 | 52.36 | 84 | 140 | tissue migration | AAMP, ACTG2, ACVRL1, AGTR2, ALOX12, ANGPT1, ANGPT2, ANXA3, APOA1, APOH, BMP4, BMPR2, KRIT1, CD63, CTSH, DCN, DPP4, HBEGF, EFNA1, EGR3, EPHA2, EMP2, ETS1, PTK2B, FAP, FGF4, FGF7, FLT4, GPLD1, GPX1, HIF1A, NR4A1, HRG, HSPB1, IFNG, INSL3, ITGA3, ITGB1, JUN, KDR, KIT, KRT2, TACSTD2, ENPP2, SERPINF1, PFN1, PFN2, PRCP, PRKCE, PRKD1, PRKX, PTEN, PTK2, PTPRM, PTPRR, RAB13, RREB1, S100A2, SOX9, SP100, SPARC, SRF, STC1, TAC1, NR2F2, VEGFC, VIL1, SCG2, ADAM9, RAB11A, NRP2, NRP1, SEMA5A, ITGB1BP1, KLF4, SLIT2, BCAR1, ZEB2, HDAC6, PDCD6, SEMA3A, CXCL13, GIPC1, STRAP |
1247 | GO:0048011 | 0.00 | 2.55 | 88.27 | 141 | 236 | neurotrophin TRK receptor signaling pathway | ADCY3, ADCY5, ADCY6, ADCY9, AGTR2, ANGPT1, ARAF, ARHGAP4, BAD, CALM1, CALM3, CAMK4, CAMK2A, CASP9, CD28, CD80, CD86, CDKN1A, CHUK, AP2S1, CLTA, CREB1, CRKL, CSF2RB, HBEGF, DUSP4, DUSP5, ELK1, ERBB2, EREG, FGD1, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FYN, GRB2, RAPGEF1, GRIN2A, NRG1, NR4A1, IL2RA, IRAK1, ITPR1, ITPR2, KIT, KRAS, MARK3, KITLG, FOXO4, NTRK1, NTRK2, OMG, PEBP1, PCSK6, PCSK5, PDE1B, PIK3CB, PPP2R5D, PPP5C, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCE, PRKCI, MAPK8, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, PTPRA, RAC1, RAF1, RALA, RASA2, RIT1, RPS6KA1, RPS6KB2, SORT1, SHC1, SOS1, SOS2, STAT3, ADAM17, TSC2, UBB, VAV1, FGF23, CUL3, PEA15, RIPK2, HDAC3, ARHGEF7, KALRN, ARHGEF1, ARHGEF2, ARHGEF6, PSMF1, NRG2, BCAR1, RAPGEF2, ARHGEF11, ARHGEF17, PSMD6, RBX1, BCL2L11, AKAP9, RASA4, PSME3, PSMD14, SPRY1, VAV3, SLC9A6, FRS3, AKAP13 |
1248 | GO:0030855 | 0.00 | 2.54 | 23.49 | 38 | 64 | epithelial cell differentiation | ACADVL, AKT2, ALDOC, ANXA7, CAPN5, CASP6, CBR1, CD63, TPP1, CNN3, CPS1, DAB2, DLX5, DLX6, NR5A2, FZD2, HHEX, JUN, SMAD3, MGMT, NTRK3, PCNA, PGK1, PSAP, PTHLH, SIX1, TAGLN, TST, UPK1B, UPK2, UPK3A, VIL1, WNT1, TAGLN2, CBFA2T2, DHRS9, RAB10, UPK1A |
1249 | GO:0042129 | 0.00 | 2.54 | 20.52 | 33 | 55 | regulation of T cell proliferation | ANXA1, CD3E, CD4, CD6, CD28, CD80, CD86, CD59, CLC, EFNB1, HES1, IFNG, IGF1, IGF2, IGFBP2, IL12B, IL15, IL18, IRF1, LMO1, CD46, PRKCQ, RAC2, SOS1, SOS2, STAT5B, TNFSF4, VCAM1, TNFSF9, TNFSF18, TNFSF13B, HHLA2, CORO1A |
1250 | GO:0002065 | 0.00 | 2.53 | 29.92 | 48 | 80 | columnar/cuboidal epithelial cell differentiation | JAG1, ARNTL, ASCL1, ATOH1, ATP2B2, BAD, BCL2, PRDM1, BMP4, BMP6, KLF5, CDK6, CDKN1A, CDX2, EDN3, EMX1, GATA4, GATA6, GFI1, GNAQ, HIF1A, HES1, RBPJ, IL13, KIT, KITLG, CITED1, RAB27A, RAC1, RARA, RARB, RFX3, RHEB, RXRA, SOD1, SOX10, SOX11, TYMS, TYRP1, CLRN1, WNT11, TP63, USP13, SLC9A3R1, SLC4A7, CLOCK, ZEB2, SEC24B |
1251 | GO:0030902 | 0.00 | 2.53 | 28.05 | 45 | 75 | hindbrain development | AARS, ABAT, ABL1, ABL2, AGTR2, ARCN1, PHOX2A, ASCL1, RERE, ATP2B2, BCL2, CACNA1A, CTNNA2, LPAR1, EGR2, EN1, KAT2A, GRID2, FOXA2, HNRNPD, HES1, IGF1, ITGB1, KCNC1, SMAD1, SMAD9, OGDH, OTX1, OTX2, PTN, PTPRS, SCN5A, SSTR2, NR2C2, WNT1, USP9X, FZD4, ATRN, ALDH1A2, PHOX2B, NRXN1, SLC4A7, SEC24B, ATG7, TBR1 |
1252 | GO:0019722 | 0.03 | 2.53 | 7.45 | 12 | 20 | calcium-mediated signaling | AGTR1, ATP1A2, BTK, CASQ1, CCR5, P2RY11, PPP3R1, SELE, LAT2, EIF2AK3, HDAC4, NUDT4 |
1253 | GO:0071456 | 0.00 | 2.53 | 20.55 | 33 | 55 | cellular response to hypoxia | ADRB2, BAD, BCL2, BDKRB2, BNIP3, BNIP3L, CCNB1, CLCA1, EIF4EBP1, GATA6, GNB1, GNGT1, ICAM1, IRAK1, KCND2, KCNK2, KCNK3, PRKAA1, PRKCE, PTEN, PTGIS, PTN, S100B, SLC2A4, SLC8A3, SLC9A1, STC1, SUV39H1, TRPC1, TWIST1, OGT, ACAA2, USP19 |
1254 | GO:0000187 | 0.00 | 2.53 | 24.31 | 39 | 65 | activation of MAPK activity | ADRA2A, ALK, CD81, CSPG4, DUSP5, LPAR1, EFNA1, ERCC6, ERN1, FPR1, GNG3, GRM1, HGF, IL1B, IRAK1, IRAK2, ITGA1, KIT, MAP3K5, MAP3K11, NTF3, NTRK3, P2RX7, PDE6G, PDE6H, PIK3CB, PRKAA1, PTPN1, SHC1, SOD1, TP73, UBB, IKBKG, MAPKAPK5, PEA15, RIPK1, RIPK2, S1PR2, MAP4K5 |
1255 | GO:0006935 | 0.00 | 2.53 | 117.92 | 188 | 320 | chemotaxis | ABL1, ABL2, ACTB, ACTG1, APP, ARAF, ATOH1, CACNB3, CACNB4, CALM1, CALM3, CAMK2A, CD72, CDC42, CHN1, AP2S1, CLTA, CCR3, CCR8, ACKR2, COL3A1, COL4A3, COL4A5, COL5A2, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2RB, CSNK2A1, CSNK2A2, DCC, DCX, DLG3, DLX5, DNM1, DPYSL3, DUSP5, TYMP, EFNA1, EFNA3, EFNA4, EFNB1, EGR2, EPHA1, EPHA5, EPHA8, EPHB2, EPHB3, ERBB2, EREG, ETV4, EXT1, FGF3, FGF5, FGFR3, FGFR4, FPR1, FPR3, FYN, GFRA1, CCR10, XCR1, GRB2, GRIN2A, ARHGAP35, SERPIND1, HSPA8, HSP90AA1, HSP90AB1, IL2RA, ISL1, ITGA5, ITGB1, KIF5A, KRAS, ABLIM1, LIMK1, MARK3, KITLG, NRCAM, NRTN, NTRK1, NTN3, OR1D2, OTX2, PEBP1, ENPP2, PPP5C, PSPN, RELN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTAFR, PTK2, PTPRA, PTPRM, RAF1, RALA, RASA2, RNASE2, RPL24, RPS6KA1, SCN5A, SDC2, SDCBP, SHC1, SIAH1, ST6GAL1, SOS1, SOS2, SPN, CNTN2, TNR, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, FOSL1, FGF23, CUL3, CNTNAP1, KLF7, UNC5C, NUMB, PEA15, NRP2, ARHGEF7, RPS6KA4, KALRN, USP14, NRXN3, NRXN1, PSMF1, NRG2, FEZ2, RAPGEF2, ARHGEF11, FARP2, PSMD6, RBX1, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, PSME3, PSMD14, SPON2, CAP1, ARPC1A, DPYSL4, CXCR6, TBR1, CHL1, CCR9, FRS3, VAX1 |
1256 | GO:0002027 | 0.03 | 2.53 | 7.46 | 12 | 20 | regulation of heart rate | AGTR2, CALM1, CALM3, CASQ2, CAV3, PLN, SCN10A, SREBF1, TAC1, IRX5, SEMA3A, BVES |
1257 | GO:0007292 | 0.00 | 2.53 | 16.81 | 27 | 45 | female gamete generation | ANG, ATM, BCL2, BRCA2, CCNB1, DIAPH2, ERCC1, PTK2B, FSHB, FSHR, GDF9, HEXB, IGF1, IHH, INSL3, PDE3A, PPP2R1A, AURKA, TAF4B, FOSL1, USP9X, PDE5A, DYNLL1, REC8, BCL2L10, TOB2, DDX20 |
1258 | GO:0051899 | 0.01 | 2.53 | 13.07 | 21 | 35 | membrane depolarization | ABL1, ATP1A2, CACNA1A, CACNA1B, CACNB3, CACNB4, CASP1, CDKN2A, CHRNB2, JUN, KCNH2, KCNJ2, P2RX4, PRKCZ, SCN1A, SCN2A, SCN3A, SCN4B, SCN7A, SCN8A, CACNG2 |
1259 | GO:0098792 | 0.00 | 2.53 | 20.57 | 33 | 55 | xenophagy | ANXA5, COX8A, CLDN7, EIF2S1, STOM, FCGR3B, FGF7, SLC37A4, GABRA5, KCNQ1, MDH1, NTHL1, PDK4, PEX13, SERPINB10, SCN1A, SLC1A3, SNRPD1, STAT2, ZNF189, CHAF1B, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H3F, CHST3, NUP93, PHYHIP, IST1, FGFBP1 |
1260 | GO:0001776 | 0.00 | 2.52 | 18.70 | 30 | 50 | leukocyte homeostasis | ABL1, ANXA1, BAX, BCL2, TNFRSF17, TSC22D3, FCER1G, FLT3, HIF1A, IFNG, IL2RA, LMO1, KITLG, P2RX7, PDE4B, RAG1, SOS1, SOS2, STAT5B, ADAM17, TNFAIP3, FOXN1, IKBKG, TNFSF14, CCNB2, CHST3, BCL2L11, SIVA1, TNFSF13B, CORO1A |
1261 | GO:0098869 | 0.01 | 2.52 | 11.21 | 18 | 30 | cellular oxidant detoxification | ALB, CAT, GPX1, GPX2, GPX3, GPX7, GSTZ1, HBA2, HP, PTGS1, S100A9, SEPW1, PXDN, EPX, GSTO1, PRDX6, PRDX4, PRDX3 |
1262 | GO:0006368 | 0.00 | 2.52 | 14.96 | 24 | 40 | transcription elongation from RNA polymerase II promoter | CCNH, CCNT1, CCNT2, CDK9, ERCC3, GTF2F1, SSRP1, SUPT4H1, TAF2, TAF4B, TAF5, TAF6, TAF10, TAF13, TBP, IKBKAP, RNF8, CTDP1, RECQL5, CTR9, IKZF1, ZMYND11, ADRM1, SUPT16H |
1263 | GO:0006879 | 0.00 | 2.52 | 14.96 | 24 | 40 | cellular iron ion homeostasis | ABCB7, ACO1, ALAS2, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, BMP6, FTL, HIF1A, HPX, LTF, NUBP1, SLC11A2, SLC11A1, SOD1, ATP6V0D1, ABCG2, ATP6V1G1, HEPH, ABCB6 |
1264 | GO:0006921 | 0.01 | 2.52 | 13.09 | 21 | 35 | cellular component disassembly involved in execution phase of apoptosis | ADD1, APAF1, BIRC2, BAX, CASP6, CDH1, CDKN2A, DFFA, DNASE1L3, DSP, GAS2, KPNA1, PRKCD, PRKCQ, PTK2, SATB1, TOP2A, VIM, AIFM1, ERN2, CAPN10 |
1265 | GO:0034134 | 0.01 | 2.52 | 13.09 | 21 | 35 | toll-like receptor 2 signaling pathway | BTK, CD36, CHUK, CREB1, ATF2, CYBA, DUSP4, ELK1, F2RL1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK8, RPS6KA1, SKP1, TNFAIP3, UBB, CUL1, IKBKG, RIPK2 |
1266 | GO:0046620 | 0.01 | 2.52 | 13.09 | 21 | 35 | regulation of organ growth | ACACB, CAV3, CCNB1, CXADR, GATA4, GATA6, NRG1, HLX, RBPJ, KCNK2, PTEN, PTK2, RAG2, SOD1, TP73, WNT2, LATS1, CTDP1, AKAP6, BCL2L11, CARM1 |
1267 | GO:0070527 | 0.01 | 2.52 | 13.09 | 21 | 35 | platelet aggregation | ABAT, ACTB, ACTG1, ADRB2, ALOX12, CSRP1, FGA, FGG, GAS6, GNAS, HSPB1, ILK, PIK3CB, PRKCD, PRKCQ, PTPN6, RAP2B, STXBP1, STXBP3, TYRO3, FIBP |
1268 | GO:1900076 | 0.01 | 2.52 | 13.09 | 21 | 35 | regulation of cellular response to insulin stimulus | AHSG, AKT2, CISH, GPLD1, FFAR3, IGF2, IL1B, INS, YBX1, PRKAA1, PRKCD, PRKCQ, PRKCZ, PTPN1, PTPRE, RPS6KB1, TSC1, TSC2, OGT, PIK3R3, SOCS3 |
1269 | GO:0007405 | 0.01 | 2.52 | 11.22 | 18 | 30 | neuroblast proliferation | ASCL1, DAGLA, CTNNA1, CX3CR1, EML1, HIF1A, KCNA1, CX3CL1, SIX3, SMARCD3, SOX2, SOX10, VEGFC, FZD9, NUMB, NUMBL, RAB10, VAX1 |
1270 | GO:0035794 | 0.01 | 2.52 | 11.22 | 18 | 30 | positive regulation of mitochondrial membrane permeability | BAD, BAX, BCL2, BID, BNIP3, BNIP3L, ATF2, EYA2, SFN, PPP3R1, MAPK8, SLC9A1, YWHAZ, DYNLL1, BCL2L11, ACAA2, SIVA1, YWHAQ |
1271 | GO:0009994 | 0.02 | 2.52 | 9.35 | 15 | 25 | oocyte differentiation | ANG, ATM, BCL2, BRCA2, CCNB1, EREG, PTK2B, GDF9, IGF1, INSL3, PDE3A, PPP2R1A, AURKA, PDE5A, REC8 |
1272 | GO:0042551 | 0.02 | 2.52 | 9.35 | 15 | 25 | neuron maturation | ABL2, APP, BCL2, CLN5, EPHA8, GNAQ, NRCAM, OPA1, RAC1, RAC3, RB1, CNTN2, PICK1, FARP2, IRX5 |
1273 | GO:0048008 | 0.02 | 2.52 | 9.35 | 15 | 25 | platelet-derived growth factor receptor signaling pathway | ABL1, ABL2, BCR, F3, F7, RAPGEF1, PDGFRL, PTEN, PTPN1, PTPRJ, SNCA, NRP1, SLC9A3R1, BCAR1, TXNIP |
1274 | GO:0048260 | 0.02 | 2.52 | 9.35 | 15 | 25 | positive regulation of receptor-mediated endocytosis | ANGPT1, BICD1, CAV3, CBL, CD63, DAB2, HIP1, NTF3, SERPINE1, CCL21, SELE, SFRP4, VTN, SYNJ1, PICK1 |
1275 | GO:0060986 | 0.02 | 2.52 | 9.35 | 15 | 25 | endocrine hormone secretion | AGTR1, AGTR2, BMP6, CRH, CRHBP, CRY1, GALR1, GDF9, IL1B, INHA, KISS1, TAC1, TMF1, UCN, FZD4 |
1276 | GO:0000083 | 0.03 | 2.52 | 7.48 | 12 | 20 | regulation of transcription involved in G1/S transition of mitotic cell cycle | BACH1, CCNE1, DHFR, E2F4, E2F6, GFI1, ORC1, PCNA, RB1, RRM2, TYMS, KLF11 |
1277 | GO:0045581 | 0.03 | 2.52 | 7.48 | 12 | 20 | negative regulation of T cell differentiation | ANXA1, BMP4, CDKN2A, CTLA4, CYLD, ERBB2, HLX, IFNA2, IHH, IRF1, TNFSF4, TNFSF18 |
1278 | GO:0071622 | 0.03 | 2.52 | 7.48 | 12 | 20 | regulation of granulocyte chemotaxis | EDNRA, CXCL1, CXCL3, IL1B, RAC1, RAC2, S100A7, CCL21, XCL1, CX3CL1, TNFSF18, SLIT2 |
1279 | GO:2001240 | 0.03 | 2.52 | 7.48 | 12 | 20 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | BCL2, BCL2L1, CTNNA1, CX3CR1, EYA1, FYN, NRG1, IL1A, IL1B, PF4, CX3CL1, RIPK1 |
1280 | GO:0032944 | 0.00 | 2.51 | 28.72 | 46 | 77 | regulation of mononuclear cell proliferation | ANXA1, BCL2, CD3E, CD4, CD6, CD28, CD80, CD86, CD38, CD59, CD81, CDKN1A, CHRNB2, CLC, GPR183, EFNB1, HES1, IFNG, IGF1, IGF2, IGFBP2, IL1B, IL12B, IL13, IL15, IL18, IRF1, LMO1, CD46, PRKCQ, RAC2, ST6GAL1, SOS1, SOS2, STAT5B, TAC1, TNFSF4, TNFRSF4, VCAM1, TNFSF9, RIPK2, TNFSF18, VAV3, TNFSF13B, HHLA2, CORO1A |
1281 | GO:0048598 | 0.00 | 2.51 | 25.52 | 41 | 69 | embryonic morphogenesis | ACVR2A, ACVR2B, APLNR, APOA1, BMPR2, COL5A2, COL6A1, COL12A1, DUSP1, DUSP4, DUSP5, EXT1, EXT2, EYA2, FLT1, GATA6, FOXA2, IL1RN, ITGA3, ITGA5, ITGAV, ITGB1, ITGB4, LAMA3, SMAD1, PRKAR1A, SNAI1, TAL1, UGDH, VTN, ZBTB17, HMGA2, FZD7, CUL3, CHRD, LATS1, KLF4, CER1, CTR9, ARFRP1, TMED2 |
1282 | GO:0008286 | 0.00 | 2.51 | 69.09 | 110 | 185 | insulin receptor signaling pathway | AKT2, ANGPT1, ARAF, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, CALM1, CALM3, CAMK2A, CAV2, CSF2RB, HBEGF, DUSP5, EIF4E, EIF4EBP1, EIF4G1, ERBB2, EREG, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FYN, GPLD1, GRB2, GRIN2A, NRG1, IDE, IGF1R, IGF2, IL2RA, INS, KIT, KRAS, MARK3, KITLG, FOXO4, PEBP1, PDE3B, PDK4, PIK3C3, PIK3CB, PPM1A, PPP5C, PRKAA1, PRKAG1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTK2, PTPRA, RAF1, RASA2, RHEB, RPE65, RPS6, SHC1, SOS1, SREBF1, STK11, UBB, FGF23, CUL3, IRS4, OGT, PIK3R3, PEA15, ATP6V0D1, PSMF1, NRG2, ATP6V1G1, BCAR1, RAPGEF2, C2CD5, PSMD6, RBX1, AKAP9, RASA4, PSME3, PSMD14, BAIAP2, SORBS1, SH2B2, RRAGA, FRS3 |
1283 | GO:0007269 | 0.00 | 2.51 | 30.67 | 49 | 82 | neurotransmitter secretion | ABAT, CACNA1A, CACNA1B, CAMK2A, CHAT, CHRNB4, GAD1, GAD2, GLS, HSPA8, NTRK2, P2RX7, PARK2, PFN2, SEPT5, PSEN1, PTGER4, PTPRN2, RAB5A, SLC1A3, SLC1A6, SLC1A7, SLC6A11, SLC6A12, SLC6A13, SLC22A2, SNAP25, SNCA, STXBP1, SYN1, SYT1, SYT4, SYN3, DOC2A, CADPS, STX11, LIN7A, SYNJ1, BAIAP3, DGKI, SNAP29, NRXN3, NRXN1, NRXN2, SNCAIP, RIMS2, SNPH, CPLX2, CPLX1 |
1284 | GO:0030198 | 0.00 | 2.50 | 41.89 | 67 | 113 | extracellular matrix organization | ACTN1, APLP2, BCL3, BMP4, DST, CD151, COMP, VCAN, CTGF, ECM2, FBLN1, FBLN2, EFEMP1, FGA, FGG, GAS6, GFAP, B4GALT1, ICAM1, ICAM2, ICAM3, ICAM4, IHH, ITGA1, ITGA3, ITGA4, ITGA5, ITGA9, ITGAD, ITGAM, ITGAV, ITGAX, ITGB1, ITGB4, KDR, LAMA4, LTBP1, MATN3, MFAP3, TNFRSF11B, SERPINE1, VIT, SERPINB5, PPIB, PTK2, PTPRS, SDC2, SDC4, SPARC, SPINT1, TNR, VCAM1, VTN, PXDN, MADCAM1, RECK, ITGA8, NRXN1, SDC3, ADAMTSL2, SPOCK2, RAMP2, CRTAP, FBLN5, PRDX4, SPINK5, EMILIN1 |
1285 | GO:0007160 | 0.00 | 2.50 | 17.48 | 28 | 47 | cell-matrix adhesion | CD44, CD63, COL3A1, COL17A1, CTGF, ECM2, EDA, FGA, FGG, HOXD3, ITGA1, ITGA3, ITGA4, ITGAV, ITGB1, ITGB4, BCAM, SRF, CNTN2, VCAM1, VTN, MADCAM1, ITGA8, ADAM9, SGCE, BCL2L11, FBLN5, ADAMTS13 |
1286 | GO:0007603 | 0.00 | 2.49 | 23.19 | 37 | 62 | phototransduction, visible light | ABCA4, APOA1, OPN1SW, CALM1, CALM3, AKR1C4, CHRM1, CLPS, CNGA1, GPC4, OPN1MW, GPC3, GNAQ, GNAT1, GNB1, GNGT1, GUCA1A, GUCA1B, GUCY2F, GUCY2D, PDE6G, PRKCQ, RBP1, RBP2, OPN1LW, RCVRN, RPE65, RS1, SAG, SDC2, SDC4, AKR1C3, SLC24A1, DHRS3, GUCA1C, SDC3, GPC6 |
1287 | GO:0051050 | 0.00 | 2.49 | 38.03 | 61 | 104 | positive regulation of transport | ADRA2A, ADRB2, AHSG, ANGPT1, ANXA1, ATP2B2, AXL, BCR, BICD1, TSPO, C3, CA2, CAMK2A, CAV3, CBL, CD36, CD63, CDH3, CREBL2, DPP6, GPC3, FFAR3, HIP1, ITGAV, ITGB1, KCNC1, KCNC2, KCNE1, KCNH2, KCNJ2, KCNQ1, NTF3, P2RX1, SERPINE1, PARK2, PRKCI, RAB3B, RAP1GAP, SCN4B, SCN5A, CCL21, SELE, SFRP4, SFTPD, SLC11A1, SLC34A1, STC1, ABCC8, TUB, TULP1, VTN, WFS1, SLC30A3, CLTCL1, PIK3R3, PICK1, TSPAN1, CREB3, SORBS1, AHCYL1, ARPP19 |
1288 | GO:0008630 | 0.00 | 2.49 | 21.32 | 34 | 57 | intrinsic apoptotic signaling pathway in response to DNA damage | ABL1, ATM, BAD, BAX, BCL2, BCL2A1, BCL2L1, BCL3, BOK, BRCA1, BRCA2, CASP9, CD44, CDKN1A, CLU, EPHA2, EP300, ERCC6, SFN, HIC1, IFI16, ING2, RPS3, SNAI1, TNFRSF1A, TNFRSF1B, TP73, TPT1, XPA, DYRK2, TP63, BCL2L10, BCL2L11, CHEK2 |
1289 | GO:0046822 | 0.00 | 2.49 | 43.38 | 69 | 116 | regulation of nucleocytoplasmic transport | AGTR2, ANGPT1, BARD1, BCL3, BMP4, BMP6, BMPR1A, BRCA1, CAMK4, CD36, CDH1, CDKN1A, CDKN2A, CYLD, DAB2, EDA, GAS6, GNAQ, SFN, HCLS1, HSP90AB1, IGF1, IL1B, IL10, IL12B, IL18, KPNA1, IPO5, SMAD3, PPP1R12A, TONSL, OGG1, PRDX1, PPM1A, PPM1B, PPP3R1, PRKCD, PRKCQ, RANGAP1, RBM4, SFRP5, SLC9A1, SP100, TRIP6, ZIC1, AAAS, AKAP1, FZD7, DYRK2, CAMK1, RGS20, TNFSF14, INPP4B, HDAC3, SEMA5A, SLC9A3R1, AKAP6, LITAF, KEAP1, NUTF2, APC2, RAPGEF3, TACC3, CREB3, CHERP, RBCK1, KHDRBS1, EDAR, NUDT4 |
1290 | GO:0051701 | 0.00 | 2.49 | 25.70 | 41 | 69 | interaction with host | AXL, CAV2, CD80, CD86, SCARB2, CD81, CCR5, CR2, CXADR, DPP4, EPS15, GAS6, GYPA, ICAM1, IDE, IFIT1, IFNA2, ITGA5, ITGB1, LTF, CD46, PVR, SERPINB3, SELPLG, SLC10A1, SLC22A5, TRIM21, DYNLT1, TMPRSS2, TNFRSF4, TYRO3, UVRAG, TRIM25, VAMP8, CLDN1, IFITM3, TRIM38, SIVA1, IFITM2, WWP1, WWP2 |
1291 | GO:0043154 | 0.00 | 2.48 | 19.45 | 31 | 52 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | AKT2, BIRC2, BIRC3, XIAP, BIRC5, AVP, CD44, CSNK2A1, DHCR24, DPEP1, GAS6, SFN, GPX1, HGF, IGBP1, SERPINB9, RAF1, RAG1, RPS6KA1, SNCA, TRAF2, VIL1, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR, KLF4, PRDX3 |
1292 | GO:1903039 | 0.00 | 2.48 | 39.64 | 63 | 106 | positive regulation of leukocyte cell-cell adhesion | ANXA1, BAD, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD28, CD80, CD86, CD44, CD59, CDC42, CTLA4, DPP4, EFNB1, EGR3, FLOT2, FYN, GRB2, HLA-DQA1, HLX, HES1, IFNG, IGF1, IGF2, IGFBP2, IHH, IL1B, IL2RA, IL12B, IL15, IL18, ITGA4, CD46, PAWR, PRKCQ, PRKCZ, PTAFR, PTPN6, RAC1, RAG1, RARA, CCL21, XCL1, SPN, STAT5B, TRAF2, TNFSF4, VAV1, VCAM1, AP3B1, TNFSF14, TNFSF9, RIPK2, AP3D1, GRAP2, IKZF1, TNFSF13B, MALT1, HHLA2, CORO1A |
1293 | GO:0007586 | 0.00 | 2.48 | 13.80 | 22 | 37 | digestion | CLPS, CTRB1, CTSE, ACE, FABP2, GALR1, HTR3A, LIPC, MEP1A, MEP1B, P2RX7, PGC, PYY, SCTR, SI, SLC15A1, SSTR2, VIPR1, MGAM, LIPG, CAPN9, TREH |
1294 | GO:0022898 | 0.00 | 2.48 | 37.77 | 60 | 101 | regulation of transmembrane transporter activity | ADRA2A, ATP1A2, ATP1B3, FXYD2, BCL2, BMP4, CACNB3, CACNB4, CALM1, CALM3, CASQ2, CAV3, CFTR, CRH, CRHBP, DNM2, DRD3, STOM, PTK2B, GRK6, GSTM2, HRC, INS, KCNE1, KCNJ1, KCNJ11, KCNQ1, KCNS2, NTSR1, PDE4B, PDE4D, FXYD3, PLN, PRKCE, RELN, PTAFR, RYR2, S100A1, SCN4B, SLC9A1, SLN, TWIST1, SUMO1, KCNAB1, RIPK1, RGN, SLC9A3R1, NRXN1, GSTO1, AKAP7, AKAP6, OXSR1, KCNE2, KCNE3, AKAP9, TRDN, CACNG2, RAPGEF3, AHCYL1, WWP2 |
1295 | GO:0050777 | 0.01 | 2.47 | 13.80 | 22 | 37 | negative regulation of immune response | AMBP, ANGPT1, ANXA1, APOA1, BCR, BST2, CD59, COL3A1, HLX, IFNA2, IL2RA, IL13RA2, CD46, PTPN6, XCL1, STAT6, TNFSF4, TNFSF18, IL1RL1, IL27RA, OLFM4, SPINK5 |
1296 | GO:2000145 | 0.00 | 2.47 | 145.49 | 228 | 389 | regulation of cell motility | AAMP, ABL1, ABL2, ACVR1, ACVRL1, ADAM10, ADARB1, ADRA2A, JAG1, AGTR2, AKT2, ALOX12, ALOX15B, ANGPT1, ANGPT2, ANXA1, ANXA3, ANXA5, APOH, ARHGAP4, ARHGDIB, BBS2, BBS4, BCL2, BCR, BMP4, BMPR2, BST2, KRIT1, CD63, CD81, CDK6, CGA, COL1A1, COL3A1, CLDN7, CSF1R, CTNNA1, CTSH, CX3CR1, DAB2, DAPK3, DCN, ACE, DIAPH1, DPEP1, DPYSL3, HBEGF, ECM1, S1PR1, LPAR1, EDN3, EDNRA, EFNA1, EPHA2, EMP2, EPHA1, ETS1, F2R, F2RL1, F3, F7, F10, PTK2B, FBLN1, EFEMP1, FGF4, FGF7, FGR, FLT1, FLT4, FSHB, GAS6, GPLD1, GRB7, CXCL1, CXCL3, HGF, NRG1, HIF1A, ONECUT1, HRG, HSPB1, ICAM1, IFNG, IGF1, IGF1R, IGFBP3, IGFBP5, IL1B, ILK, INS, INSL3, ITGA3, ITGA4, ITGA5, ITGAV, ITGB1, JUN, KDR, KIT, LAMA3, LAMA4, LAMA5, TACSTD2, EPCAM, SMAD3, SMAD7, KITLG, NTF3, NTRK3, P2RY2, P2RY6, SERPINE1, PAWR, ENPP2, SERPINF1, PF4, PF4V1, PFN1, PFN2, PRCP, PRKCE, PRKD1, PRKX, RELN, PTAFR, PTEN, PTGER4, PTK2, PTN, PTPRJ, PTPRM, PTPRR, RAC1, RAC2, RAF1, RAP2A, RAP2B, RDX, RPS6KB1, RREB1, S100A7, SERPINB3, CCL20, CCL21, CCL24, CCL25, CXCL6, CXCL5, XCL1, CX3CL1, SDC4, SDCBP, SELE, SELP, SEMA3F, SEMG1, SGK1, SNAI1, SOX9, SP100, SPARC, SRF, STAT3, STC1, STK10, TAC1, ADAM17, NR2F2, TRIP6, TWIST1, VEGFB, VEGFC, VIL1, VTN, WNT11, SEMA3B, MADCAM1, SOX14, RECK, IKBKAP, UNC5C, CHRD, NUMB, TNFSF14, ADAM15, ADAM9, RAB11A, TNFRSF18, NRP2, NRP1, ARHGEF7, TNFSF18, SEMA5A, RGN, ITGB1BP1, KLF4, SLIT2, SLC9A3R1, ONECUT2, BAG4, CXCL14, BCAR1, RAPGEF2, SEMA3E, SLK, HDAC4, HDAC6, PDCD6, RNF41, TRIB1, CITED2, SEMA3A, ATP8A1, RAPGEF3, CREB3, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, CXCL13, NRG3, IL24, ABHD2, CORO1A, STRAP |
1297 | GO:0043627 | 0.00 | 2.47 | 16.29 | 26 | 44 | response to estrogen | ADRB2, APOA1, STS, BGLAP, CA2, CRH, CTNNA1, DTYMK, EP300, F7, GATA4, GATA6, GHRHR, KRT19, LDHA, SMAD6, CITED1, TNFRSF11B, SERPINB9, PTPRN, STAR, TSHB, TRIM25, TRIM24, CITED2, SLC34A2 |
1298 | GO:0045766 | 0.00 | 2.47 | 25.81 | 41 | 69 | positive regulation of angiogenesis | ACVRL1, ADM, ALOX12, ANGPT2, ANXA3, BRCA1, BTG1, C3, CCR3, CTSH, CX3CR1, ECM1, EPHA1, ETS1, F3, PTK2B, FLT1, GATA4, GATA6, UTS2R, HGF, HIF1A, HSPB1, IL1A, IL1B, ISL1, ITGA5, KDR, NTRK1, SERPINE1, PRKD1, PTGIS, CCL24, CX3CL1, TWIST1, VEGFB, VEGFC, SEMA5A, PDCD6, RAMP2, RAPGEF3 |
1299 | GO:1903035 | 0.01 | 2.47 | 11.93 | 19 | 32 | negative regulation of response to wounding | ABAT, ALOX12, ANXA5, APOH, SERPING1, F2, FAP, FGA, FGG, GP1BA, HMGCR, HRG, KLKB1, KNG1, SERPINE1, SERPINB2, TNR, USF1, VTN |
1300 | GO:0048568 | 0.00 | 2.47 | 26.39 | 42 | 71 | embryonic organ development | ADM, ARNT, ASCL2, PRDM1, BMPR1A, CDX2, CDX4, DDIT3, ERCC1, ERCC3, FLT3LG, GAMT, GJA5, GJB5, GRB2, HHEX, RBPJ, IL10, ITGA4, KDR, KIT, KRT19, LLGL2, KITLG, CITED1, PBX1, PCSK5, RAD23B, RARA, RBBP6, SNAI1, SPINT1, ST14, TAL1, NR2F2, VCAM1, WNT2, ALDH1A2, SOCS3, SH2B3, CITED2, TMED2 |
1301 | GO:0090559 | 0.01 | 2.46 | 13.84 | 22 | 37 | regulation of membrane permeability | BAD, BAX, BCL2, BCL2L1, BID, BNIP3, BNIP3L, CAMK2A, CNP, ATF2, EYA2, SFN, PPP3R1, MAPK8, SLC9A1, STAT3, YWHAZ, DYNLL1, BCL2L11, ACAA2, SIVA1, YWHAQ |
1302 | GO:0051017 | 0.02 | 2.46 | 10.06 | 16 | 27 | actin filament bundle assembly | ABL2, ACTN1, ADD1, CDC42, DPYSL3, EPS8, PTK2B, MYO1B, PAWR, FSCN1, SRF, HSP90B1, CUL3, GAS7, BAIAP2, SORBS1 |
1303 | GO:0060425 | 0.01 | 2.45 | 11.97 | 19 | 32 | lung morphogenesis | BMP4, CDC42, CTSH, CTSZ, FGF7, GATA4, HHEX, FOXA2, IGF1, KRAS, SRSF6, SOX2, SOX9, SOX11, SRF, WNT2, WNT2B, SPRY1, SEC24B |
1304 | GO:0001952 | 0.02 | 2.45 | 10.07 | 16 | 27 | regulation of cell-matrix adhesion | ACVRL1, ARHGAP6, BCL2, CDKN2A, DAPK3, EFNA5, ONECUT1, SERPINE1, PIK3CB, PTEN, PTK2, SLC9A1, ADAM15, ONECUT2, SEMA3E, SLK |
1305 | GO:0060348 | 0.00 | 2.45 | 36.65 | 58 | 98 | bone development | ATP6AP1, BGLAP, BMP4, BMP6, BMPR2, RUNX2, SERPINH1, CDX1, CHAD, COL1A1, COL9A1, COMP, DLX5, EP300, ESR1, FGF4, FGFR3, FLI1, GNAS, HOXD11, IGF1, INPPL1, INSIG1, KIT, LTF, SMAD1, SMAD9, PEX7, PIP4K2A, PPIB, PTGER4, PTHLH, PTPN6, RARA, RARB, RYR1, SOX9, SPARC, SRD5A1, SRF, STC1, TAL1, TULP3, TWIST1, TYROBP, WHSC1, WNT1, DCHS1, PAPSS2, RGN, DHRS3, CER1, SETDB1, ABI1, WASF2, LRRC17, CARM1, SEMA4D |
1306 | GO:0006959 | 0.00 | 2.45 | 26.50 | 42 | 71 | humoral immune response | A2M, ADM, ANG, APP, KLK3, BCL2, BST2, CD28, CD37, CD59, DMBT1, GPR183, FAU, FCN2, FGA, CFHR1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, RBPJ, KRT1, LTF, CFP, PGC, RPL39, SEMG1, ST6GAL1, SLPI, TAC1, VIP, VTN, HIST1H2BG, HIST2H2BE, HIST1H2BJ, SPON2, CXCL13, TRAF3IP2, SPINK5 |
1307 | GO:0050896 | 0.00 | 2.45 | 35.03 | 60 | 124 | response to stimulus | ACO1, AK4, AMPD1, ANXA11, ATP12A, ATP4A, ATP5D, ATP5G3, BBS1, ENTPD6, CPOX, CRX, CTPS1, CYB5A, EMX1, EMX2, GAD1, GAD2, GOT2, GYS2, HPS1, AFF3, LUM, NRL, PFAS, ATP8B1, PFKFB2, PGGT1B, ABCD3, RPN2, SCN8A, SCNN1A, SCNN1G, SEPW1, SLC6A11, SLC15A2, SLC22A1, SLC22A2, SLC22A5, SRP14, SRP19, SRP68, TAF2, TBCE, TNNT2, TOP1, USH2A, CLRN1, SLC30A2, SLC30A3, SLC30A4, SLC10A3, BFSP2, SLC25A12, SLC22A8, ABCG2, SLC25A13, IRX5, UGT2A1, KERA |
1308 | GO:0010001 | 0.00 | 2.45 | 16.38 | 26 | 44 | glial cell differentiation | ABL1, ABL2, AKT2, CDK6, EGR2, EMX1, F2, FGF5, GFAP, HMBS, IGF1, IL1B, ILK, KRAS, NTRK3, RELN, S100A8, S100A9, S100B, SOD1, SPINT1, STAT3, VIM, RNF112, PHOX2B, PICK1 |
1309 | GO:0006171 | 0.03 | 2.44 | 8.18 | 13 | 22 | cAMP biosynthetic process | ADCY3, ADCY5, ADCY6, ADCY9, ADRA2A, APLP1, DRD3, LPAR1, GALR1, GRM8, PALM, AKAP6, GABBR2 |
1310 | GO:0009612 | 0.00 | 2.44 | 27.12 | 43 | 73 | response to mechanical stimulus | ANGPT2, ATP2B2, BGLAP, CCNB1, ENTPD2, CLCN6, COL3A1, COL11A1, DCN, ETS1, F3, PTK2B, FYN, GATA4, GFI1, IGF1, IGFBP2, JUND, KCNA1, KCNC1, KCNK2, KIT, NTRK1, NTRK2, P2RX3, P2RX7, P2RY1, PAWR, EIF2AK2, PSPH, RPS6KB1, SLC1A3, SLC12A2, SOX2, UCN, XPA, XPC, FOSL1, TRPA1, NRXN1, NRXN2, PIEZO1, TXNIP |
1311 | GO:0051436 | 0.00 | 2.44 | 26.55 | 42 | 71 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | ATM, BUB1B, CCNB1, CDC20, CDC27, CENPF, DUSP1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, TTK, UBB, ZNF207, CDC23, CDC16, ZW10, PSMF1, PSMD6, PSME3, PSMD14, ANAPC10, MAD2L2, UBE2C |
1312 | GO:0001885 | 0.02 | 2.44 | 10.10 | 16 | 27 | endothelial cell development | S1PR3, F2RL1, GPX1, RAPGEF1, ICAM1, IL1B, PDE4D, PROC, PTPRS, RDX, STC1, TNFRSF1A, VEZF1, S1PR2, RAPGEF2, RAPGEF3 |
1313 | GO:0031663 | 0.02 | 2.44 | 10.10 | 16 | 27 | lipopolysaccharide-mediated signaling pathway | PRDM1, BMP6, CD6, HCK, IL1B, IL18, IRAK1, IRAK2, LTF, CD180, PRKCE, PTAFR, STAT1, TNFAIP3, RIPK2, TRIB1 |
1314 | GO:0034260 | 0.02 | 2.44 | 10.10 | 16 | 27 | negative regulation of GTPase activity | ARL2, BBS4, GPS2, IPO5, PTPRN2, RDX, RGN, DGKI, SLIT2, RASA4, TNK2, SPRY1, ARFGEF1, TMED2, FICD, FZD10 |
1315 | GO:0060415 | 0.02 | 2.44 | 10.10 | 16 | 27 | muscle tissue morphogenesis | COL3A1, COL11A1, DSP, S1PR1, FZD2, NRG1, RBPJ, ISL1, SMAD7, RXRA, RYR2, TNNC1, TNNI3, TNNT2, WNT2, HAND1 |
1316 | GO:0045860 | 0.00 | 2.44 | 72.24 | 114 | 195 | positive regulation of protein kinase activity | ABL1, ACVR2B, ADCY3, ADCY5, ADCY6, ADCY9, ADRB2, ANG, ANGPT1, ARAF, BAX, BMP4, CAMK2A, CD4, CDKN1A, CENPE, CLU, CRKL, CSF2RB, ACE, HBEGF, EFNA5, EMP2, EREG, F2R, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FYN, GAS6, GCG, GRB2, RAPGEF1, GRIN2A, NRG1, IL2RA, IL12B, INS, MARK3, NTRK1, PEBP1, PPP5C, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCZ, EIF2AK2, RELN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTK2, PTPRA, RAF1, RASA2, CCL21, SDC4, SLC11A1, SOS1, STK10, STK11, UCN, WNT11, FGF23, CUL3, ADAM9, UNC119, VAPB, ITGB1BP1, TAOK2, PSMF1, NRG2, SLK, ATG13, PSMD6, OXSR1, RBX1, ABI1, TOM1L1, AKAP9, RASA4, PSME3, PSMD14, STK25, NRG3, FRS3, JTB |
1317 | GO:0008344 | 0.00 | 2.44 | 18.33 | 29 | 49 | adult locomotory behavior | APP, ARCN1, ATP1A2, ATP1A3, CACNA1A, CACNB4, CLCN3, CNP, CTNS, DNM1, EPS8, GLRA1, FOXA2, HOXD9, HOXD10, KCNJ10, NTF4, NTSR1, PARK2, SCN1A, SCN8A, SNCA, CNTN2, TBCE, TMOD1, TSC1, ZIC1, ATG7, CHL1 |
1318 | GO:0048589 | 0.00 | 2.44 | 15.08 | 24 | 41 | developmental growth | ADM, ANXA1, BMPR1A, DMBT1, ENO3, GAS1, GPX1, HOXD11, IGFBP5, LIPC, SMAD3, PRKCQ, RAD51B, SOX2, SOX10, TBCE, TYMS, EIF4H, FZD7, ADAM15, CFLAR, CTR9, GINS1, SETDB1 |
1319 | GO:0030856 | 0.00 | 2.43 | 14.53 | 23 | 39 | regulation of epithelial cell differentiation | ALOX12, ALOX15B, ASCL1, ATOH1, BMP4, BMP6, BTG1, DMBT1, SFN, IL1B, KDR, PRKX, PROC, SFRP4, SOX2, STAT5B, TNFRSF1A, PAX8, PTCH2, NUMB, S1PR2, KEAP1, TRIM16 |
1320 | GO:0008285 | 0.00 | 2.43 | 119.62 | 187 | 321 | negative regulation of cell proliferation | ACVRL1, ADARB1, ADM, AGTR2, ALOX15B, APOH, ATM, AZGP1, ADGRB1, BAX, BCHE, BCL2, BDKRB2, PRDM1, BMP4, BMPR2, BRCA2, KLF9, BTG1, CAV2, CBLB, KRIT1, CD9, TNFRSF8, CD37, CDK6, CDKN1A, CDKN2A, COL4A3, ATF2, CSF1R, CTLA4, CTNNA1, CTSV, CXADR, DFNA5, DHCR24, DLG3, EMP3, ERBB2, EREG, ETS1, ETV3, ETV4, F2R, FABP6, FABP7, PTK2B, FAP, FBLN1, FGFR3, FLT3, FRK, B4GALT1, GPC3, SFN, GPLD1, RAPGEF1, CXCL1, HIST1H2AE, HMGA1, HRG, IFIT3, IGF1, IGFBP6, RBPJ, IHH, IL1A, IL1B, IL2RA, IL10, IDO1, ING2, INPPL1, INSL3, IRF1, ITGA1, ITGB1, JARID2, JUN, KCNK2, KISS1, SMAD1, SMAD3, SMAD6, FOXO4, NTRK1, OVOL1, PAWR, SERPINF1, PRKAR1A, EIF2AK2, PTEN, PTHLH, PTPN6, PTPRJ, PTPRM, RAF1, RAP1GAP, RARA, RARB, RB1, REST, RXRA, S100A11, XCL1, SFRP4, SFRP5, SFTPD, SLIT3, SMARCA2, SOD2, SOX2, SOX9, SPARC, SPINT1, SPN, SRF, SSTR2, STAT1, STAT3, STK11, STRN, TAF6, ZEB1, NR2F2, KLF10, TP73, TSC1, TSC2, TSG101, SCGB1A1, VEGFC, WNT11, FZD5, SCG2, AIMP2, FOSL1, BAP1, SRPX, CUL4A, CUL2, CUL1, KLF11, PPM1D, PDE5A, BECN1, TRIM24, KAT2B, ALDH1A2, PHOX2B, RGN, IL1RL1, ITGB1BP1, CNOT8, CER1, SLIT2, SLC9A3R1, ADAMTS1, EEF1E1, TP53I11, RAPGEF2, HDAC4, DLEC1, FGFBP1, NR2E3, ABI1, RNF41, DHRS2, SPRY1, SPEG, PEMT, IFI30, GPNMB, CHERP, PRDX4, CGRRF1, TOB2, GJB6, COPS8, IL24, VAX1, PIM2, GLMN, STRAP, WDR6, DDX20 |
1321 | GO:0014013 | 0.00 | 2.43 | 16.46 | 26 | 44 | regulation of gliogenesis | ASCL2, BMP4, TSPO, CREB1, DRD3, EMX1, ETV5, F2, EFEMP1, FGFR3, GFAP, HES1, IL1B, NTF3, NTRK3, PRKCI, PTN, RHEB, SOX10, SOX11, SPINT1, CNTN2, TP73, RNF112, RNF10, OLIG2 |
1322 | GO:0035773 | 0.03 | 2.43 | 8.22 | 13 | 22 | insulin secretion involved in cellular response to glucose stimulus | ADCY5, ADRA2A, EFNA5, EPHA5, HMGCR, FOXA2, PRKCE, PTPRN, PTPRN2, RAF1, HMGN3, NRXN1, NR1H4 |
1323 | GO:0002088 | 0.03 | 2.43 | 8.22 | 13 | 22 | lens development in camera-type eye | CDK2, CDK4, CRYBA1, CTNS, LIM2, SMAD3, NTRK3, TMOD1, VIM, WNT2, WNT2B, BFSP2, ZEB2 |
1324 | GO:1901292 | 0.00 | 2.43 | 22.81 | 36 | 61 | nucleoside phosphate catabolic process | ARNT, CAT, ENTPD2, CNP, DUT, GPD1, GPX1, HIF1A, HPRT1, IGF1, INS, NTHL1, OGG1, P2RX7, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, ENPP3, PGAM1, PRKAA1, PRKAG1, STAT3, UNG, UPP1, OGT, PDE5A, MBD4, HDAC4, RAPGEF3, PDE10A |
1325 | GO:0050867 | 0.00 | 2.42 | 55.35 | 87 | 148 | positive regulation of cell activation | ANXA1, AXL, BAD, BCL2, PRDM1, BTK, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD28, CD80, CD86, CD38, CD59, CD81, CDC42, CDKN1A, CHRNB2, CTGF, CTLA4, DPP4, GPR183, EFNB1, EGR3, F2RL1, FCER1G, FGR, FLOT2, FLT3LG, FYN, GAS6, GRB2, HLA-DQA1, HLX, HES1, IFNG, IGF1, IGF2, IGFBP2, IHH, IL1B, IL2RA, IL12B, IL13, IL15, IL18, CD46, PRKCQ, PRKCZ, PTAFR, PTPN6, RAC1, RAG1, RARA, RPS6KA1, CCL21, XCL1, SELP, SPN, STAT5B, STAT6, TAC1, TRAF2, TNFSF4, TNFRSF4, UNG, VAV1, VCAM1, WHSC1, AP3B1, VAMP8, TNFSF14, TNFSF9, RIPK2, AP3D1, IL1RL1, GRAP2, GAB2, IKZF1, VAV3, TNFSF13B, MALT1, HHLA2, CORO1A |
1326 | GO:0007595 | 0.03 | 2.42 | 8.23 | 13 | 22 | lactation | APRT, ATP2B2, ATP7B, CCND1, CDO1, CHUK, CREB1, GHRHR, HIF1A, OXTR, PAM, STAT5B, EIF2AK3 |
1327 | GO:0046326 | 0.03 | 2.42 | 8.23 | 13 | 22 | positive regulation of glucose import | AKT2, CREBL2, GPC3, FFAR3, IGF1, INS, PRKCI, PRKCZ, CLTCL1, PIK3R3, SORBS1, ARPP19, CAPN10 |
1328 | GO:0046627 | 0.03 | 2.42 | 8.23 | 13 | 22 | negative regulation of insulin receptor signaling pathway | AHSG, CISH, IL1B, YBX1, PRKCD, PRKCQ, PRKCZ, PTPN1, PTPRE, RPS6KB1, TSC1, TSC2, SOCS3 |
1329 | GO:0071825 | 0.03 | 2.42 | 8.23 | 13 | 22 | protein-lipid complex subunit organization | ABCA1, AGTR1, APOA1, ARF1, ACSL3, LCAT, LIPC, NR1H2, SOAT2, DGAT1, LIPG, ABCG1, ABCA7 |
1330 | GO:1901028 | 0.03 | 2.42 | 8.23 | 13 | 22 | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | BAD, BAX, BCL2, BID, SFN, PPP3R1, MAPK8, YWHAZ, DYNLL1, BCL2L11, ACAA2, SIVA1, YWHAQ |
1331 | GO:2000514 | 0.03 | 2.42 | 8.23 | 13 | 22 | regulation of CD4-positive, alpha-beta T cell activation | ANXA1, CD80, CD86, HLX, IFNG, IL12B, PRKCQ, PRKCZ, RARA, XCL1, TNFSF4, RIPK2, TNFSF18 |
1332 | GO:1903321 | 0.00 | 2.42 | 40.02 | 63 | 107 | negative regulation of protein modification by small protein conjugation or removal | ABL1, ATM, BUB1B, TSPO, CCNB1, CDC20, CDC27, CDKN2A, CENPF, CRY1, DUSP1, FYN, DNAJB2, LIMK1, SMAD7, PRKCE, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, RPS3, TRIM21, TNFAIP3, TTK, UBB, USP4, WNT1, ZNF207, OGT, CDC23, CDC16, ZW10, ATG5, PSMF1, BAG5, PSMD6, PSME3, PSMD14, HMG20B, ANAPC10, PIAS3, MAD2L2, UBE2C, GLMN |
1333 | GO:0030072 | 0.00 | 2.42 | 34.23 | 54 | 92 | peptide hormone secretion | ACVR2B, ADCY5, ANXA1, ARL2, ARNTL, CACNA1A, CHRM3, CNR1, EDN3, EFNA5, EPHA5, GLP1R, GNAS, FFAR3, FOXA2, HTR2C, IFNG, IL1B, IL1RN, ITPR1, ITPR2, KCNC2, KCNS3, PDE3B, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PTPRN, PTPRN2, RAB1A, RAF1, RFX3, SLC2A1, SLC16A1, SNAP25, STXBP1, STXBP3, SYT5, HNF1A, VIP, PAX8, SYT7, HMGN3, NRXN1, EIF2AK3, CLOCK, RIMS2, NR1H4, RAPGEF3, CPLX1, RAPGEF4 |
1334 | GO:1901606 | 0.00 | 2.42 | 20.92 | 33 | 56 | alpha-amino acid catabolic process | AHCY, ARG1, ASL, AUH, CCBL1, CRYM, GAD1, GAD2, GLS, GLUD1, GLUL, GOT1, GOT2, GPT, GSTZ1, HAL, HMGCL, HNMT, IDO1, IVD, ALDH6A1, OAT, OGDH, OTC, PAH, QDPR, TAT, DDO, ALDH4A1, KYNU, AASS, ALDH1L1, HIBADH |
1335 | GO:0023014 | 0.00 | 2.42 | 179.52 | 278 | 480 | signal transduction by protein phosphorylation | ABL1, ABL2, ACVR1, ACVR2A, ACVR2B, ACVRL1, ADRA1B, ADRA2A, ADRB2, ALK, AMBP, AMHR2, ANGPT1, ARAF, ATP6AP1, AVP, BMP1, BMP3, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, C3, CALM1, CALM3, CAMK2A, CAV2, CAV3, CD36, CD44, CD81, CDC42, CHUK, CCR5, CREB1, ATF2, CRKL, CRYBA1, CSF1R, CSF2RB, CSPG4, CTGF, CTSH, GADD45A, HBEGF, DUSP1, DUSP4, DUSP5, GPR183, LPAR1, EDN3, EDNRA, EFNA1, EPHA2, ELK1, EPHA7, EPHA8, EPHB1, ERBB2, EREG, ERCC6, ERN1, ESR1, F2R, F2RL1, PTK2B, FBLN1, FGA, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FGG, FLT1, FLT3, FLT4, FPR1, FSHR, FYN, GAS6, GCG, GDF9, GNG3, GPS2, GRB2, RAPGEF1, GRIN2A, GRM1, HGF, NRG1, HMGCR, HTR2C, ICAM1, IGBP1, IGF1, IGF1R, IGF2, IGFBP3, IL1A, IL1B, IL2RA, IL18, ILK, INHA, INS, IRAK1, IRAK2, ITGA1, ITGAV, ITGB1, JUN, KCNH2, KDR, KISS1, KIT, KRAS, SMAD1, MARK3, MAP3K5, KITLG, MAP3K11, NRTN, NTF3, NTRK1, NTRK2, NTRK3, TNFRSF11B, OXTR, P2RX7, P2RY1, PEBP1, PRDX1, PARK2, PDE6G, PDE6H, PER1, PIK3CB, PPP2R1A, PPP2R5D, PPP5C, PRKAA1, PRKCD, PRKCE, PRKCZ, MAPK8, EIF2AK2, PSAP, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTGER4, PTK2, PTPN1, PTPN6, PTPRA, PTPRJ, PTPRR, RAF1, RAP2A, RASA2, RBM4, RGS2, RPS3, RPS6KA1, RYK, S100A7, S100A12, SERPINB3, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDCBP, SHC1, SKP1, SOD1, SOS1, SOX2, SOX9, STK10, STYX, XCL2, TNFRSF1B, TP73, TPD52L1, NR2C2, TRAF2, TSG101, TNFRSF4, TYRO3, UBB, VEGFB, VRK2, FZD5, SCG2, ARHGEF5, FGF23, FZD4, FZD7, FZD8, CUL3, CUL1, IKBKG, MAPKAPK5, PDE5A, PEA15, RIPK1, ADAM9, RIPK2, TNFRSF6B, NRP1, HDAC3, ITGB1BP1, GPR55, S1PR2, KLF4, TAOK2, SLC9A3R1, ARHGEF6, PSMF1, GDF15, NRG2, TRAF4, RAPGEF2, SLK, RB1CC1, ZEB2, PSMD6, OXSR1, RBX1, SH2D3C, SH2D3A, RANBP9, AKAP9, RASA4, ATP6AP2, SORBS3, RNF41, PSME3, PSMD14, TRIB1, SPRY1, TNIP1, ABCA7, STK25, ARL6IP5, ZMYND11, FRS3, COPS5, MAP4K5, FZD10 |
1336 | GO:1901360 | 0.01 | 2.42 | 9.82 | 16 | 29 | organic cyclic compound metabolic process | BCHE, BTD, CYP2F1, SARDH, GSTM1, GSTM2, HLCS, P4HA1, SHMT2, SLC34A1, GGH, VNN2, SLC5A6, P4HA2, CRTAP, PRDX4 |
1337 | GO:0010508 | 0.00 | 2.42 | 14.59 | 23 | 39 | positive regulation of autophagy | ADRB2, BAD, BNIP3, BNIP3L, DCN, HIF1A, IFNG, KDR, PAFAH1B2, PIK3CB, PIP4K2A, PRKAA1, TRIM21, STK11, UVRAG, EPM2A, BECN1, ATG5, TMEM59, TRIM13, TRIM22, ATG7, PIM2 |
1338 | GO:0030100 | 0.00 | 2.41 | 42.64 | 67 | 114 | regulation of endocytosis | ABL1, ABL2, AHSG, ANGPT1, ARF1, ARF6, AXL, BCR, BICD1, BLK, C3, CAV3, CBL, CD36, CD63, AP2S1, CYBA, DAB2, DNM2, F2RL1, FCER1G, FGR, GAS6, GPC3, HCK, HIP1, IL1B, ITGAV, ITGB1, NTF3, SERPINE1, PIK3CB, PRKD1, PTEN, PTPN1, RAB4A, RAB5A, RAB5B, RAB27A, RAB5C, RAC1, RAP1GAP, CCL21, SDCBP, SELE, SFRP4, SFTPD, SLC11A1, SNCA, TSC2, TSG101, TUB, TULP1, NR1H2, VTN, PICALM, SYNJ1, UNC119, PICK1, ZFYVE16, SNX17, DNAJC6, SNAP91, TSPAN1, TNK2, ABCA7, STON1 |
1339 | GO:0007613 | 0.00 | 2.41 | 19.05 | 30 | 51 | memory | ATP1A3, CHAT, CHRNB2, CNR1, COMT, CREB1, CX3CR1, DBH, FEN1, GRIN2A, HRH1, HRH2, IGF1, IGF2, IL1B, ITGA3, ITGA5, KCNK2, OXTR, SERPINF1, PSEN1, PTEN, PTGS1, S100B, SLC8A3, ITGA8, KAT2B, RIN1, RCAN2, ABCA7 |
1340 | GO:0072358 | 0.00 | 2.41 | 89.30 | 140 | 242 | cardiovascular system development | AAMP, ACVRL1, ADRB2, ALOX12, ANG, ANGPT1, ANGPT2, ANXA3, APOH, KLK3, ADGRB1, ADGRB2, BAX, BMPR2, BRCA1, KLF5, BTG1, C3, KRIT1, CDX2, CDX4, CCR3, COL1A1, COL4A3, COL15A1, CSPG4, CTGF, CTH, CTSH, CX3CR1, DCN, DDIT3, DHCR7, TYMP, ECM1, EGR3, EPHA2, EMP2, EPHA1, EPHB1, EPHB2, EPHB3, EREG, ETS1, F3, PTK2B, FAP, FLT1, FLT4, B4GALT1, GJA4, GPLD1, UTS2R, GPX1, RAPGEF1, GTF2I, HGF, NR4A1, HPGD, HRG, HSPB1, IGF1, IL1A, IL1B, IL18, ITGA5, ITGAV, KCNJ1, KCNQ1, KDR, KRT1, LAMA5, LLGL2, MEOX2, FOXO4, CITED1, NRCAM, NTRK1, NTRK2, SERPINE1, PDE3B, ENPP2, SERPINF1, PF4, PIK3CB, PRRX1, PRCP, PRKD1, PRKX, PTGER4, PTGIS, PTPRM, S100A7, CCL24, CX3CL1, SHB, SMARCA2, SP100, SPINT1, SRPK2, STAT1, STK11, TAL1, NR2F2, TNFAIP3, VEGFC, VEZF1, FZD5, SCG2, FOSL1, FZD4, FZD8, RECK, FOXN1, SERPINB7, NRP2, SOCS3, SEMA5A, ITGB1BP1, KLF4, SLIT2, NRXN3, NRXN1, QKI, EIF2AK3, SLC4A7, RAPGEF2, SEMA3E, CUL7, SLC12A6, PDCD6, WASF2, RAPGEF3, VAV3, CXCL13, PDPN, TMED2, SPINK5, ESM1, GLMN |
1341 | GO:0007601 | 0.00 | 2.41 | 49.74 | 78 | 133 | visual perception | ABCA4, AOC2, ARR3, BBS1, BBS2, BBS4, OPN1SW, CACNB4, CDH3, CHRNB2, CNGA1, COL1A1, COL11A1, CRX, CRYBA1, CRYBA4, CRYGB, CRYZ, EYA4, EYA3, EFEMP1, GABRR2, OPN1MW, GJA3, GLRA1, GNAT1, GNAT2, GRM8, GUCA1A, GUCA1B, GUCY2F, GUCY2D, HPS1, IMPG1, KCNJ10, ABLIM1, LUM, TACSTD2, NRL, OAT, OPA1, SIX6, PDC, PDE6G, PDE6H, RABGGTA, RABGGTB, OPN1LW, RCVRN, PRPH2, RGR, RGS16, RPGR, RPE65, RS1, SAG, SFRP5, SIX3, TULP1, TULP2, TYR, USH2A, CLRN1, WFS1, ZIC2, SOX14, BFSP2, SEMA5A, UNC119, SLC24A1, DHRS3, SLC4A7, GUCA1C, NR2E3, IRX5, RRH, OCLM, KERA |
1342 | GO:0010033 | 0.00 | 2.40 | 20.05 | 33 | 62 | response to organic substance | ALB, AMPD1, ATP5G3, ATRX, DAGLA, CASQ1, CHAT, COL6A2, EPS8, ERCC1, GLUL, GOT2, GPX3, GYS2, PFKFB2, RFC3, SEL1L, SGTA, ST6GAL1, SLC6A12, RNF103, FZD5, USP13, USP14, GPR55, SETDB1, TRIM13, MARCH6, ERLIN1, USP19, MALT1, OS9, ERLIN2 |
1343 | GO:0007422 | 0.01 | 2.40 | 12.72 | 20 | 34 | peripheral nervous system development | AKT2, ALDH3A2, ADGRB1, ADGRB2, EGR2, EGR3, ERBB2, NRG1, HOXD9, HOXD10, ILK, ISL1, NTF3, NTRK2, SCN8A, SLC5A3, SOD1, SOX10, TBCE, ONECUT2 |
1344 | GO:0035567 | 0.01 | 2.40 | 12.72 | 20 | 34 | non-canonical Wnt signaling pathway | ABL1, ABL2, CDC42, CSNK1D, DAB2, GPC4, FZD2, RAC1, RYK, SFRP4, SFRP5, WNT11, FZD5, FZD4, FZD6, FZD7, FZD8, FZD9, GPC6, FZD10 |
1345 | GO:0045670 | 0.01 | 2.40 | 12.72 | 20 | 34 | regulation of osteoclast differentiation | ATP6AP1, BGLAP, CA2, CAMK4, CREB1, CSF1R, FSHB, FSHR, GNAS, IFNG, IL12B, IL17A, LTF, KLF10, TYROBP, INPP4B, GPR55, LRRC17, FSTL3, TOB2 |
1346 | GO:0048208 | 0.01 | 2.40 | 12.72 | 20 | 34 | COPII vesicle coating | AREG, CD59, CSNK1D, CTSZ, GOLGA2, GRIA1, LMAN1, PPP6C, RAB1A, TRAPPC2, TRAPPC10, CUL3, USO1, SEC22B, GOSR2, PREB, SEC24B, SEC23A, SEC24A, TMED2 |
1347 | GO:0048704 | 0.01 | 2.40 | 12.72 | 20 | 34 | embryonic skeletal system morphogenesis | ALX3, BMP4, RUNX2, COL11A1, EYA1, GNAS, HOXC11, HOXD3, HOXD9, HOXD10, HOXD11, SMAD3, PRRX1, SIX1, SOX11, ZEB1, TULP3, TWIST1, EIF4A3, IRX5 |
1348 | GO:0072329 | 0.00 | 2.40 | 23.56 | 37 | 63 | monocarboxylic acid catabolic process | ABAT, ACAA1, ACACB, ACADL, ACADM, ACADS, ACADSB, ACADVL, AGXT, AKT2, ABCD1, CNR1, CPT1B, CPT2, CRAT, DECR1, ECH1, FAAH, GOT2, IDUA, IVD, LIPE, PEX7, PEX13, ABCD3, SORD, TWIST1, ACOX2, ACOX3, ALDH4A1, XYLB, ACOT8, AKR1A1, ECI2, SLC25A17, SLC27A4, SLC27A2 |
1349 | GO:0006006 | 0.00 | 2.39 | 19.70 | 31 | 53 | glucose metabolic process | ACACB, CACNA1A, CALM1, CALM3, SLC37A4, GAA, GCGR, GYS2, FOXA2, ONECUT1, IGFBP3, IGFBP5, INPPL1, KCNJ11, KHK, PARK2, PDK4, PHKA1, PHKA2, PHKB, PHKG1, PRKAA1, PYGB, PYGL, PYGM, SORD, UBB, UGP2, USF1, EPM2A, AKR1A1 |
1350 | GO:0022407 | 0.03 | 2.39 | 8.87 | 14 | 24 | regulation of cell-cell adhesion | CAMK4, CLC, EFNA5, EPHA7, EPHB3, LMO1, RAC2, SOD1, SOS1, SOS2, ZEB1, FOXN1, SOX13, SPINK5 |
1351 | GO:0050778 | 0.00 | 2.39 | 18.36 | 29 | 50 | positive regulation of immune response | ANXA1, CD80, CNR1, FCER2, FFAR3, HLX, HRG, IFNG, IL13, IL15, IDO1, P2RX7, PGC, PRKCZ, PTAFR, RARA, XCL1, SLC11A1, STAT6, TRAF2, TNFSF4, UNG, WHSC1, FZD5, VAMP8, IL27RA, GAB2, SPON2, TNFSF13B |
1352 | GO:0090068 | 0.00 | 2.39 | 28.66 | 45 | 77 | positive regulation of cell cycle process | ATM, ATRX, BRCA1, CCNB1, CDK2, CDKN1A, CDKN2A, CTGF, FAP, GATA6, FOXO4, ORC1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, SFPQ, TP73, UBB, RNF112, HMGA2, CRADD, PSMF1, PSMD6, PSME3, PSMD14, USP19 |
1353 | GO:1902600 | 0.00 | 2.39 | 21.66 | 34 | 58 | hydrogen ion transmembrane transport | ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP1A4, ATP4A, ATP4B, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, COX4I1, COX5B, COX6A1, COX6B1, COX7A1, COX7C, COX8A, COX15, CYB5A, SLC11A2, SLC9A1, SLC9A2, SLC9A3, SLC9A5, UQCRC1, UQCRH, ATP6V0D1, COX7A2L, ATP6V1G1, SLC9A6, UQCR11 |
1354 | GO:2000241 | 0.00 | 2.39 | 21.67 | 34 | 58 | regulation of reproductive process | ARHGDIB, BMP4, CDC20, CNR1, DUSP1, ESR1, NR5A1, GDF9, B4GALT1, GLRA1, GPR3, OVGP1, OVOL1, OXTR, P2RY1, P2RY2, SERPINF1, PRKACB, PRKAR1A, PTAFR, PTGER4, RAD1, RXRA, SNAI1, SOX9, SPINK1, SRY, STK11, VIP, ZP2, TPST2, CITED2, SEMA3A, PRDX4 |
1355 | GO:0050729 | 0.00 | 2.39 | 21.69 | 34 | 58 | positive regulation of inflammatory response | AGTR1, C3, CD6, CD28, CNR1, EDNRA, FCER1G, FFAR3, IL1B, IL12B, IL15, IL17A, IL18, IDO1, KLKB1, SERPINE1, PTGER4, RPS19, S100A8, S100A9, S100A12, CCL24, XCL1, CX3CL1, STAT5B, XCL2, TAC1, TNFRSF1A, TNFSF4, VAMP8, TNFSF18, IL1RL1, CLOCK, TNIP1 |
1356 | GO:0043065 | 0.00 | 2.38 | 75.56 | 118 | 204 | positive regulation of apoptotic process | ABL1, ADM, ADRB2, ALDH1A3, ALOX12, ANXA1, ANXA5, ARHGAP4, BARD1, BCL2A1, BMP4, BNIP3L, BOK, TSPO, CAMK2A, CASP1, CCK, TNFRSF8, CDK4, CDKN2A, CNR1, COL4A3, CREB1, CRYBA1, CTGF, CTLA4, GADD45A, DFFA, DNM2, DUSP1, LPAR1, EEF1A2, EIF2S1, ERCC3, F2R, F3, FAP, FGD1, B4GALT1, GPLD1, GRIN2A, HIF1A, HIP1, HMGCR, HRG, PRMT2, IFNG, IGFBP3, IL1B, IL10, IL12B, IDO1, ING2, IRF5, ITGB1, KNG1, LDHA, MAP3K5, SLC11A2, NTRK3, NTSR1, P2RX1, P2RX7, PPID, PRKCI, EIF2AK2, PSEN1, PTGIS, PTN, RAC1, RARB, REST, RPS6, RXRA, SORT1, S100B, SFRP4, SLC9A1, SNCA, SOS1, SOS2, TOP2A, VAV1, TRPV1, WNT11, FOSL1, HMGA2, NSMAF, KLF11, UNC5C, AKR1C3, RIPK2, TSC22D1, ALDH1A2, ARHGEF7, KALRN, LATS1, ARHGEF2, SLIT2, ARHGEF6, EEF1E1, RAPGEF2, ARHGEF11, ARHGEF17, TNFSF15, CASP8AP2, PDCD6, BCL2L10, SAP18, VAV3, ATG7, ARL6IP5, TXNIP, RNPS1, CAPN10, CHEK2, AKAP13, DDX20 |
1357 | GO:0034146 | 0.02 | 2.38 | 10.85 | 17 | 29 | toll-like receptor 5 signaling pathway | CHUK, CREB1, ATF2, DUSP4, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK8, RPS6KA1, SKP1, TNFAIP3, UBB, CUL1, IKBKG, RIPK2 |
1358 | GO:0051702 | 0.02 | 2.38 | 10.85 | 17 | 29 | interaction with symbiont | APCS, CAV2, CHD1, EP300, STOM, F2RL1, GPX1, JUN, LTF, PARK2, PPIB, REST, SMARCA4, SP1, HMGA2, VAPB, RAB9A |
1359 | GO:0055013 | 0.02 | 2.38 | 10.85 | 17 | 29 | cardiac muscle cell development | AGTR2, BMP4, CAV3, CCNB1, CXADR, GATA4, SGCB, SRF, CSRP3, SORBS2, CTDP1, AKAP6, ATG5, MAML1, SPEG, ATG7, BVES |
1360 | GO:0060411 | 0.02 | 2.38 | 10.85 | 17 | 29 | cardiac septum morphogenesis | ACVR1, JAG1, FZD2, GATA4, GATA6, GJA5, HES1, ISL1, SMAD7, RARA, RARB, SOX11, WHSC1, WNT11, DHRS3, HAND1, CITED2 |
1361 | GO:0021700 | 0.00 | 2.38 | 40.31 | 63 | 108 | developmental maturation | ABL2, ANG, APP, ASCL1, AXL, BCL2, BRCA2, BTK, RUNX2, CBFB, CCNB1, CD63, CDC20, CDKN1A, CFTR, CLCN3, CLN5, EPHA8, EREG, PTK2B, GHRHR, GNAQ, HIF1A, HES1, IHH, IL15, INSL3, KDR, NRCAM, OPA1, PALM, PDE3A, PGR, PPP2R1A, RELN, PTEN, RAC1, RAC3, RB1, RFX3, CCL21, SIX3, SOX10, AURKA, STXBP1, SYP, TAL1, CNTN2, TYMS, FZD5, PICALM, BFSP2, AP1M1, AP3D1, NRXN3, NRXN1, PICK1, FARP2, REC8, FEM1B, IRX5, KLF2, RAB32 |
1362 | GO:0008543 | 0.00 | 2.38 | 70.69 | 110 | 189 | fibroblast growth factor receptor signaling pathway | ADCY3, ADCY5, ADCY6, ADCY9, ANGPT1, ARAF, BAD, CALM1, CALM3, CAMK4, CAMK2A, CASP9, RUNX2, CBL, CD28, CD80, CD86, CDKN1A, CHUK, CREB1, CSF2RB, CTGF, HBEGF, DUSP5, ERBB2, EREG, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FYN, GRB2, GRIN2A, NRG1, NR4A1, IL2RA, ITPR1, ITPR2, KIT, KRAS, MARK3, KITLG, FOXO4, OTX2, PEBP1, PDE1B, PIK3CB, PPP2CB, PPP2R1A, PPP5C, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCE, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, PTPRA, RAF1, RASA2, RPS6KB2, SHC1, SOS1, TSC2, UBB, VAV1, SHOC2, FGF23, CUL3, PEA15, FIBP, PSMF1, NRG2, RAPGEF2, PSMD6, RBX1, FGFBP1, AKAP9, RASA4, PSME3, PSMD14, SPRY1, FRS3 |
1363 | GO:0009408 | 0.00 | 2.37 | 33.29 | 52 | 89 | response to heat | ATM, ATR, BAG1, CAMK2A, CASQ1, CDKN1A, CETN1, DHX9, DNMT1, EIF2S1, EIF2B1, EP300, HSPA6, HSPA8, HSPB2, HSP90AA1, HSP90AB1, IGF1, IL1A, IL1B, IL1R1, IRAK1, ATXN3, NUP88, NUP98, P2RX3, PRKCQ, RANBP2, RPA2, RPA3, RPS6KB1, ST8SIA1, SOD1, DNAJC7, TRPV1, NUP214, AAAS, EIF2B3, EIF2B2, EIF2B5, SOCS3, BAG5, BAG4, BAG3, NUP155, NUP93, HDAC6, PDCD6, NUP50, ARPP21, NUPL2, PSIP1 |
1364 | GO:0035725 | 0.00 | 2.37 | 28.80 | 45 | 77 | sodium ion transmembrane transport | ARF1, ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP1A4, ATP1B3, FXYD2, ATP4A, HCN2, CAV3, DNM2, DRD3, STOM, FXYD3, PRKCE, SCN1A, SCN2A, SCN3A, SCN4B, SCN5A, SCN7A, SCN8A, SCN10A, SCNN1A, SCNN1B, SCNN1G, SLC5A5, SLC8A3, SLC9A1, SLC9A2, SLC9A3, SLC9A5, SLC12A3, SLC13A1, SLC20A1, TRAPPC10, TRPM2, SLC4A4, SLC24A1, SLC9A3R1, SLC4A7, HCN4, SLC9A6, SLC34A2 |
1365 | GO:0060429 | 0.00 | 2.37 | 17.71 | 28 | 49 | epithelium development | ARG2, ATM, BMPR1A, CAT, CDX1, EN1, EP300, GJA4, GJA5, EPCAM, SMAD1, SMAD6, SMAD7, SMAD9, MEOX2, OTX2, RAD51B, RBBP6, XRCC2, RGS20, CHRD, CRLF1, CER1, IFT140, ABI1, ATP6AP2, CITED2, DMRT2 |
1366 | GO:0030335 | 0.00 | 2.37 | 35.11 | 55 | 95 | positive regulation of cell migration | ACVR1, ADRA2A, AKT2, CGA, COL1A1, CSF1R, DAB2, DAPK3, DIAPH1, S1PR1, EPHA1, F2R, F10, FBLN1, FGR, FLT1, FSHB, GRB7, HGF, ONECUT1, IGF1R, ILK, INS, ITGA5, ITGAV, ITGB1, KIT, SMAD3, NTF3, NTRK3, RELN, PTK2, RDX, SERPINB3, SDCBP, SEMA3F, SNAI1, TRIP6, WNT11, SEMA3B, IKBKAP, NUMB, ARHGEF7, ONECUT2, BAG4, RAPGEF2, SEMA3E, SEMA3A, ATP8A1, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, CORO1A |
1367 | GO:0043067 | 0.00 | 2.37 | 172.75 | 267 | 473 | regulation of programmed cell death | AARS, ABL2, ACTN1, ACVR1, ADAR, AKT2, ALB, ALK, ALX3, ANGPT1, XIAP, BIRC5, APOH, ARAF, ATOH1, AVP, AXL, BAG1, BCL3, BDKRB2, BLK, BMP1, BMP3, BMP6, BMP8B, BNIP2, BRCA1, BTK, CACNA1A, CASP4, CASP5, CAT, CBL, KRIT1, CD3E, CD3G, CD38, CD44, CD59, CNTF, COMP, CLDN7, CSF1R, CSNK2A1, CTH, CX3CR1, DAB2, DAD1, DBH, DHCR24, DPEP1, TSC22D3, EDNRA, EGR3, CTTN, ERCC5, ESR1, ETS1, EYA1, PTK2B, FCER1G, FGA, FGF4, FGG, FLT3, FLT4, FYN, GABRA5, GAS1, GAS6, GATA6, GCG, GDF9, GPX1, GRID2, GRINA, HCK, HCLS1, HGF, NRG1, HSPA9, HSPB1, HSP90AB1, ICAM1, IFIT3, IGBP1, IGF1, IGF1R, IHH, IL1A, IL13, ILK, INHA, INS, INSL3, IRAK1, ISL1, ITGA5, ITGAV, KCNJ1, KDR, KIT, KRAS, KRT18, LTF, EPCAM, SMAD6, KITLG, MGMT, CITED1, YBX1, NTF3, NTF4, NTRK2, OGG1, OPA1, TNFRSF11B, PA2G4, PAFAH2, SERPINE1, SERPINB2, PAX4, PCP4, PDE3A, PDK4, PF4, SERPINB9, SERPINB13, PIM1, PRKAA1, PRKCQ, PRKCZ, PROC, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTK2, PTPN1, RAF1, RAG1, RARA, RPS3A, RPS6KA1, RPS6KB1, CCL21, CX3CL1, SET, SGK1, ST6GAL1, STIL, SIX1, SNAI1, SNCB, SOD2, SON, SOX2, SOX9, SOX10, SP100, STAR, STAT1, STAT3, STAT5B, AURKA, STK10, STXBP1, SUPV3L1, ADAM17, TMF1, TNFAIP3, TNFRSF1A, TNFRSF1B, TPT1, HSP90B1, TRAF1, TWIST1, TNFRSF4, TYRO3, UCN, UNG, VDAC2, VEGFB, VIL1, VIP, WFS1, WNT1, XRCC2, ZNF16, PAX8, SCG2, CBX4, API5, BECN1, URI1, TNFSF14, TNFRSF6B, TNFRSF18, TNFRSF10D, TRIM24, NRP1, HDAC3, TAX1BP1, TNFSF18, SOCS3, SEMA5A, RGN, AURKB, CRLF1, KLF4, TAOK2, ATG5, PSMF1, GDF15, BAG5, BAG4, BAG3, BCAR1, TRAF4, SLK, KIAA0141, RB1CC1, PSMD6, OXSR1, NR1H4, SGK2, FEM1B, TRAP1, PSME3, DHRS2, PSMD14, RAMP2, SIGMAR1, CITED2, RAPGEF3, ACAA2, CREB3, STK25, SEMA4D, STAMBP, IVNS1ABP, CHL1, ZMYND11, PROKR1, MALT1, PRDX3, PIM2, CORO1A, MAP4K5 |
1368 | GO:0019752 | 0.00 | 2.37 | 68.38 | 107 | 187 | carboxylic acid metabolic process | AARS, ACY1, ADSS, ARG2, ATF4, CACNA1A, CKM, COMT, CTNS, CTPS1, SARDH, DNMT1, DNMT3B, EPRS, FAU, HARS, RPL10A, OAZ1, OAZ2, PEPD, PFAS, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, ST6GAL1, SLC6A6, SLC7A4, SMS, TARS, TYMS, TYR, PAX8, AIMP2, SLC7A5, GGH, RPL14, RPL23, PSMF1, EEF1E1, EIF4A3, PTDSS1, KEAP1, PSMD6, GNE, SLC25A15, PSME3, PSMD14, PEMT, ATG7, FARS2, AHCYL1, SERINC3, RPL35 |
1369 | GO:0071593 | 0.00 | 2.37 | 89.01 | 138 | 238 | lymphocyte aggregation | ABL1, ABL2, ANXA1, BAD, BAX, BCL2, BCL3, BMP4, ZFP36L2, CAMK4, RUNX2, CBLB, CCND3, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD7, CD8A, CD8B, CD28, CD80, CD86, TNFSF8, CD59, CD151, CDC42, CDK6, CDKN2A, CLC, CTLA4, CTPS1, CXADR, CYLD, DPP4, EFNB1, EGR3, ERBB2, F2RL1, FCER1G, FLOT2, FLT3, FYN, GRB2, HLA-DQA1, HLX, HES1, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF2, IGFBP2, IHH, IL1B, IL2RA, IL10, IL12B, IL15, IL18, IDO1, INS, IRF1, ITGAD, KIT, LMO1, SMAD3, CD46, P2RX7, PAWR, PRKAR1A, PRKCQ, PRKCZ, PSEN1, PTGER4, PTPN6, RAB27A, RAC1, RAC2, RAG1, RAG2, RARA, RELB, RPL22, SATB1, CCL21, XCL1, SFTPD, SLC11A1, SOD1, SOS1, SOS2, SPN, SRF, STAT5B, STAT6, STK10, STK11, ADAM17, ZEB1, TRAF2, TSC1, TNFSF4, TNFRSF4, SCGB1A1, VAV1, VCAM1, WNT1, FZD5, FZD7, FZD8, FOXN1, AP3B1, PDE5A, STX11, TNFSF14, TNFSF9, RIPK2, AP3D1, TNFSF18, SOCS6, GRAP2, SOX13, IKZF1, TNFSF13B, MALT1, SPINK5, BTN3A1, GLMN, HHLA2, CORO1A |
1370 | GO:0090090 | 0.00 | 2.36 | 31.42 | 49 | 84 | negative regulation of canonical Wnt signaling pathway | CYLD, DAB2, DDIT3, RAPGEF1, IGFBP2, IGFBP6, ISL1, PARK2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, SFRP4, SFRP5, SOX2, SOX9, SOX10, UBB, WNT11, FZD6, CUL3, RGS20, LATS1, PSMF1, PSMD6, RBX1, G3BP1, PSME3, PSMD14, APC2, MAD2L2 |
1371 | GO:0002253 | 0.00 | 2.36 | 107.34 | 166 | 287 | activation of immune response | A2M, ABL1, ACTB, ACTG1, BIRC2, BIRC3, XIAP, BAX, BCL2, BLK, BTK, SERPING1, C1QA, C1QB, C1QC, C1S, C3, C7, CACNB3, CACNB4, CALM1, CALM3, CBLB, CD3D, CD3E, CD3G, CD4, CD28, CD86, CD36, CD38, CD59, CD79B, CDC42, CHUK, CLU, CR2, CREB1, ATF2, CTLA4, CTSK, CYBA, CYLD, DMBT1, DUSP4, ELK1, EP300, F2RL1, FCER1G, FCGR1A, FCN2, FGR, FYB, FYN, GFI1, GPLD1, GRB2, HCK, CFHR1, HLA-DQA1, HSP90AA1, HSP90AB1, ICAM2, ICAM3, IFI16, IL1B, IRAK1, IRAK2, IRF1, ITGAM, ITPR1, ITPR2, JUN, KCNN4, KRAS, KRT1, LIMK1, LTF, CD46, PAWR, PDE4B, PDE4D, CFP, PIK3C3, PIK3CB, PPP2R5D, PPP3R1, PRKACB, PRKACG, PRKCD, PRKCE, PRKCQ, MAPK8, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, PTPN6, PTPRJ, RAC1, RAF1, RELB, RPS6KA1, SEC14L1, SKP1, STK11, TNFAIP3, HSP90B1, TYRO3, UBB, UBE2D2, VAV1, VTN, LAT2, CUL1, IKBKG, RIPK1, RIPK2, UBA3, GRAP2, THEMIS2, PSMF1, BCAR1, ELMO1, PSMD6, TRIL, NR1H4, ABI1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, WASF2, PSME3, PSMD14, TNIP1, VAV3, BAIAP2, ARPC1A, RBCK1, CNPY3, MALT1, BTN3A1 |
1372 | GO:0051781 | 0.00 | 2.36 | 17.92 | 28 | 48 | positive regulation of cell division | BIRC5, CAT, CD28, EDN3, EREG, FGF3, FGF4, FGF5, FGF7, IGF1, IGF1R, IGF2, IL1A, IL1B, INS, YBX1, PTEN, PTN, RB1, AURKA, TAL1, VEGFB, VEGFC, ZNF16, BECN1, ITGB1BP1, DLGAP5, UBE2C |
1373 | GO:0034112 | 0.00 | 2.36 | 38.52 | 60 | 103 | positive regulation of homotypic cell-cell adhesion | ANXA1, BAD, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD28, CD80, CD86, CD44, CD59, CDC42, CTLA4, DPP4, EFNB1, EGR3, FLOT2, FYN, GRB2, HLA-DQA1, HLX, HES1, IFNG, IGF1, IGF2, IGFBP2, IHH, IL1B, IL2RA, IL12B, IL15, IL18, CD46, PRKCQ, PRKCZ, PTPN6, RAC1, RAG1, RARA, CCL21, XCL1, SPN, STAT5B, TRAF2, TNFSF4, VAV1, VCAM1, AP3B1, TNFSF14, TNFSF9, RIPK2, AP3D1, GRAP2, IKZF1, TNFSF13B, MALT1, HHLA2, CORO1A |
1374 | GO:0008625 | 0.01 | 2.36 | 13.44 | 21 | 36 | extrinsic apoptotic signaling pathway via death domain receptors | BAD, BAX, BCL2, BID, MAL, SORT1, SP100, TNFRSF1A, TRAF2, TRADD, RIPK1, CRADD, TNFSF10, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, BAG3, KIAA0141, CASP8AP2, FEM1B |
1375 | GO:0006753 | 0.00 | 2.36 | 84.43 | 131 | 227 | nucleoside phosphate metabolic process | ABCA1, ACACB, ACPP, ADCY3, ADCY5, ADCY6, ADCY9, ADM, ADRA2A, ADRB2, ADSL, ADSS, AMPD1, AMPD2, APLP1, APRT, ATP1A2, ATP2B2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V0A1, ATP5O, AVP, AVPR2, TSPO, CACNB4, CALCR, CALM1, CALM3, CDA, COX4I1, COX8A, COX15, CRH, CTNS, CTPS1, DHFR, DRD3, DRD5, TYMP, LPAR1, EDNRA, PTK2B, FSHR, FZD2, GALR1, GCG, GHRH, GHRHR, GLP1R, GNAL, GNAS, GRM8, GUCA1A, GUCA1B, GUCA2A, GUCA2B, GUCY1B3, GUCY2C, GUCY2F, GUCY2D, HMGCR, HSPA8, HTR2C, IDH1, IMPDH1, IMPDH2, INSL3, LDHC, MDH1, MDH2, NTRK1, NTRK2, OAS2, P2RY11, PALM, PF4, PFAS, PRPSAP1, PTGER4, PTGIS, PTHLH, RAF1, RCVRN, RPE, RRM1, SDHC, SHMT1, SNCA, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, TAZ, TYMS, UCN, UQCRC1, UQCRC2, UQCRH, VIP, VIPR2, WFS1, PDHX, SUCLG1, KYNU, PAPSS2, PAPSS1, AKAP6, TBPL1, TP53I3, ATP5J2, GABBR2, AKAP12, GUCA1C, SLC25A13, CALCRL, RAMP2, ATP5H, CAP1, ATP5L, SLC26A1, NUDT4 |
1376 | GO:0051090 | 0.00 | 2.36 | 41.71 | 65 | 112 | regulation of sequence-specific DNA binding transcription factor activity | ALK, ANXA3, BTK, CAMK2A, CHUK, CLU, ATF2, CTH, EDA, EP300, EPHA5, FZD2, HCK, ICAM1, IL1B, IL10, INS, JUN, KIT, KRAS, LTF, NTRK1, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK8, EIF2AK2, RELN, PSMA6, PTEN, RPS3, S100A8, S100A9, S100A12, SGK1, SMARCA4, SRF, TAF6, TRAF1, TRAF2, UBB, WNT1, WNT2, ZIC2, TRIM25, ARHGEF5, FOSL1, FZD4, IKBKG, TRADD, RIPK1, RIPK2, CFLAR, BUD31, RPS6KA4, TNFSF18, ARHGEF2, CLOCK, RNF41, TRIM13, TRIM22, TRIM38, MALT1, PRDX3 |
1377 | GO:1904951 | 0.01 | 2.35 | 14.04 | 22 | 38 | positive regulation of establishment of protein localization | ARF6, BCL2, BID, CCT6A, DKC1, EPHA2, ITGA3, ITGB1, PRKCI, MAPK8, VIL1, YWHAZ, DYNLL1, NRXN1, BCL2L11, RAMP3, CCT7, CCT4, CCT2, SORBS1, YWHAQ, RER1 |
1378 | GO:0010595 | 0.01 | 2.35 | 13.46 | 21 | 36 | positive regulation of endothelial cell migration | AAMP, ALOX12, ANGPT1, ANXA3, BMP4, BMPR2, ETS1, PTK2B, FLT4, GPLD1, HSPB1, KDR, PRKD1, SPARC, VEGFC, NRP2, NRP1, SEMA5A, ITGB1BP1, BCAR1, PDCD6 |
1379 | GO:0032781 | 0.03 | 2.35 | 8.98 | 14 | 24 | positive regulation of ATPase activity | ADRB2, ALDOB, ATP1B3, DNM2, PFN1, PFN2, RAB4A, RYR2, SETMAR, TNNT2, SUMO1, RGN, ABCA7, RAPGEF3 |
1380 | GO:0051148 | 0.03 | 2.35 | 8.98 | 14 | 24 | negative regulation of muscle cell differentiation | BMP4, CAV3, DDIT3, EREG, IL18, FOXO4, YBX1, SOX9, CSRP3, CFLAR, HDAC3, CTDP1, CXCL14, HDAC4 |
1381 | GO:0070231 | 0.03 | 2.35 | 8.98 | 14 | 24 | T cell apoptotic process | BAX, BMP4, CLC, DFFA, TSC22D3, HIF1A, IL2RA, IDO1, PRKCQ, RAG1, RIPK1, BCL2L11, PDCD7, SIVA1 |
1382 | GO:1902667 | 0.03 | 2.35 | 8.98 | 14 | 24 | regulation of axon guidance | BMPR2, SEMA3F, SEMA3B, NRP1, SEMA5A, SLIT2, SEMA3E, SEMA3A, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, TBR1 |
1383 | GO:0051495 | 0.00 | 2.35 | 16.02 | 25 | 43 | positive regulation of cytoskeleton organization | APOA1, CCNB1, CFL2, CTGF, LPAR1, EPHA1, F2RL1, HCLS1, LIMK1, SMAD3, NTF3, NTRK3, P2RX7, PFDN2, PRKCQ, S100A10, SDC4, TAC1, WNT11, ARHGEF5, BECN1, SEMA5A, ITGB1BP1, SORBS3, RAPGEF3 |
1384 | GO:0071902 | 0.00 | 2.35 | 48.93 | 76 | 131 | positive regulation of protein serine/threonine kinase activity | ADRA2A, ALK, CCND1, CALM1, CALM3, CCNC, CCND3, CCNH, CCNT1, CCNT2, CD81, CSF1R, CSPG4, GADD45A, DUSP5, LPAR1, EDN3, EFNA1, ERBB2, ERCC6, ERN1, ACSL1, PTK2B, FLT1, FLT3, FPR1, GNG3, GRM1, HGF, HSP90AB1, IGF2, IL1B, ILK, IRAK2, ITGA1, KIT, KRAS, LTF, MAP3K5, KITLG, MAP3K11, NTF3, NTRK3, P2RX7, PDE6G, PDE6H, PIK3CB, PIM1, PRKAA1, PSEN1, PTPN1, RPS3, S100A12, SHC1, STIL, SNCA, SOD1, ADAM17, TP73, TPD52L1, UBB, FZD5, ARHGEF5, FZD4, FZD8, CAMK1, MAPKAPK5, PDE5A, PEA15, RIPK1, RIPK2, S1PR2, RAPGEF2, ZEB2, MAP4K5, FZD10 |
1385 | GO:0007173 | 0.00 | 2.35 | 86.02 | 133 | 230 | epidermal growth factor receptor signaling pathway | ABL1, ABL2, ADAM10, ADCY3, ADCY5, ADCY6, ADCY9, ADRA2A, ANGPT1, APLP2, APP, ARAF, AREG, BAD, CALM1, CALM3, CAMK4, CAMK2A, CASP9, CBL, CD28, CD80, CD86, CDC42, CDKN1A, CHUK, AP2S1, CLTA, CREB1, CSF2RB, HBEGF, DUSP5, EPS8, EPS15, ERBB2, EREG, ESR1, PTK2B, EFEMP1, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FYN, GRB2, GRB7, GRIN2A, NRG1, NR4A1, IL2RA, ITGA1, ITPR1, ITPR2, KIT, KRAS, MARK3, KITLG, FOXO4, PEBP1, PDE6G, PDE6H, PDE1B, PIGR, PIK3CB, PPP5C, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCE, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, PTPRA, PTPRJ, RAF1, RASA2, RPS6KB2, SHC1, SOS1, SOX9, ADAM17, TSC2, UBB, VAV1, VIL1, RAB7A, STAM, FGF23, CUL3, PEA15, ARHGEF7, REPS2, PSMF1, NRG2, BCAR1, RAPGEF2, PSMD6, RBX1, AKAP9, RASA4, PSME3, PSMD14, SPRY1, STAM2, FRS3 |
1386 | GO:0061564 | 0.00 | 2.35 | 159.73 | 245 | 428 | axon development | ABL1, ABL2, ACTB, ACTG1, ADAM10, ANGPT1, APP, ARAF, ARHGAP4, ATOH1, ADGRB1, BMPR2, CACNA1A, CACNB3, CACNB4, CALM1, CALM3, CAMK2A, CCK, CD72, CDC42, CHN1, CHRNB2, AP2S1, CLTA, CNP, CNR1, COL3A1, COL4A3, COL4A5, COL5A2, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2RB, CSNK2A1, CSNK2A2, CTNNA2, DCC, DCX, DLG3, DLX5, DNM1, DNM2, DPYSL3, EPYC, HBEGF, ECM2, DUSP5, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EPHA2, CTTN, EPHA1, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, ERBB2, EREG, ETV4, EXT1, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FYN, GDI1, GFRA1, GOLGA4, GRB2, GRIN2A, ARHGAP35, NRG1, HSPA8, HSP90AA1, HSP90AB1, IFRD1, IL2RA, ILK, ITGA1, ITGA5, ITGA9, ITGAV, ITGB1, KIF5A, KIT, KRAS, ABLIM1, LIMK1, MARK3, KITLG, NRCAM, NRTN, NTF3, NTRK1, NTRK2, NTN3, OGN, OTX2, PEBP1, PPP5C, PRKCQ, PSPN, RELN, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTK2, PTPRA, PTPRM, RAC1, RAC2, RAF1, RASA2, RNF6, RPL24, RPS6KA1, RYK, S100A6, S100B, SCN5A, SDC2, SDCBP, SEMA3F, SHC1, SIAH1, SLIT3, SOS1, SOS2, SPAST, SRF, CDKL5, STK11, STXBP1, CNTN2, TBCE, TOP2B, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, SEMA3B, FGF23, RND2, USP9X, PICALM, CUL3, CNTNAP1, KLF7, UNC5C, NUMB, PEA15, RAB11A, NRP2, NRP1, ARHGEF7, PHOX2B, RPS6KA4, KALRN, SEMA5A, ARHGEF1, NUMBL, SLIT2, NRXN3, NRXN1, PSMF1, NRG2, AATK, FEZ2, RAPGEF2, SEMA3E, IST1, ARHGEF11, FARP2, PSMD6, RBX1, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN2, ARPC2, AKAP9, RASA4, PSME3, PSMD14, SEMA3A, SPON2, VAV3, BAIAP2, SLC9A6, CAP1, STK25, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, ATG7, ARPC1A, DPYSL4, TBR1, CHL1, FRS3, RAB10, AFG3L2, VAX1 |
1387 | GO:0014033 | 0.00 | 2.34 | 20.57 | 32 | 55 | neural crest cell differentiation | ACVR1, JAG1, BMPR1A, EDN3, EDNRA, EFNB1, NRG1, HIF1A, HES1, ISL1, LAMA5, KITLG, NRTN, PAX3, SEMA3F, SOX9, SOX10, SOX11, TWIST1, SEMA3B, NRP1, ALDH1A2, PHOX2B, SEMA5A, SEMA3E, ZEB2, SEMA3A, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B |
1388 | GO:0019233 | 0.00 | 2.34 | 16.06 | 25 | 43 | sensory perception of pain | CHRNB2, CNR1, CNR2, DLG2, EDNRA, EPHB1, FYN, IAPP, IL12B, KCNA1, KCNA2, KCND2, NTRK1, P2RX4, P2RX7, P2RY1, P2RY2, PAWR, PENK, PTGS1, SCN3A, SCN10A, TAC1, TRPV1, TRPA1 |
1389 | GO:0045597 | 0.00 | 2.34 | 22.97 | 36 | 63 | positive regulation of cell differentiation | ADM, AGTR1, ALOX12, ALOX15B, ARNTL, KLF5, CCNE1, CD36, CDX2, CLU, CREBL2, CTGF, DMBT1, EDN3, FGFR3, GATA4, GATA6, GFI1, SFN, HSF4, HTR2C, IL13, INS, KDR, TACSTD2, PA2G4, PAX4, RPS6KA1, SFRP4, SULT1E1, PTCH2, SOCS3, ZEB2, RAMP2, CARM1, TRIM16 |
1390 | GO:0045087 | 0.00 | 2.34 | 129.08 | 199 | 350 | innate immune response | ABL1, ABL2, ACTB, ACTG1, ADARB1, ADCY3, ADCY5, ADCY6, ADCY9, ANG, ANGPT1, ANXA1, APCS, APP, ARAF, ART1, ASS1, AXL, BAD, BCL2, BCL2L1, BLK, C1QA, C1QB, C1QC, C1S, C3, C7, CAMK4, CAMK2A, CAPZA1, CASP1, CASP9, CD3G, CD4, CD6, CD28, CD80, CD44, CD58, CD59, CDC42, CDKN1A, CLU, CR2, CSF1R, CSF2RB, CYBB, DAPK3, DHX9, HBEGF, DUSP5, EPRS, ERBB2, PTK2B, FAU, FCGR1A, FCGR1B, FCN2, FGA, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FGR, FRK, GAPDH, GRB2, GRIN2A, NRG1, HLA-DQA1, NR4A1, HSP90AA1, ICAM1, IFNG, IFNGR1, IL1RAP, IL2RA, KIT, KLRC2, KLRD1, KRT1, LIMK1, CD180, MARK3, CD46, MAP3K5, KITLG, CIITA, FOXO4, CITED1, P2RX7, PEBP1, PRDX1, PCBP2, PDE1B, CFP, PIK3CB, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKD1, PRKCQ, PRKCSH, EIF2AK2, PTAFR, PTEN, PTK2, PTPRA, RAB27A, RAC1, RASA2, RPL39, RPS6KB2, S100A7, S100A8, S100A9, S100A12, S100B, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SFTPD, SHC1, SLC11A1, SLPI, SNCA, SOS1, SRMS, SRPK2, TRIM21, STAR, STAT6, XCL2, TAC1, TRAF2, TSC2, TYROBP, UBA7, SUMO1, VCAM1, VIP, VTN, LAT2, XRCC5, TRIM25, FGF23, HIST1H2BG, HIST2H2BE, CUL3, STX11, PEA15, TNK1, ADAM15, TAX1BP1, KYNU, HIST1H2BJ, ATG12, ARHGEF2, GRAP2, ATG5, NRG2, RAPGEF2, ELMO1, GAB2, RBX1, ABI1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, WASF2, TNK2, TRIM13, CRISP3, TRIM22, SPON2, IFI30, VAV3, BAIAP2, TRIM38, ARPC1A, TXNIP, FRS3, SERINC3, ADAMTS13, CORO1A |
1391 | GO:0051170 | 0.00 | 2.34 | 56.85 | 88 | 152 | nuclear import | ADAR, AGTR2, ANGPT1, ARNTL, RERE, BCL3, BMP4, BMP6, BMPR1A, BRCA1, CBLB, CD36, CDH1, CDKN1A, CSE1L, CYLD, DAB2, EDA, F2R, FYB, GAS6, GNAQ, HCLS1, HES1, HSP90AB1, IFNG, IGF1, IL1B, IL10, IL12B, IL18, JUN, KPNA1, KPNA2, KPNA3, KPNA4, KPNA5, TNPO1, IPO5, SMAD3, TONSL, NUP88, NUP98, OGG1, OR1D2, PRDX1, PPM1A, PPM1B, PPP3R1, PRKCD, PRKCQ, RAN, RANBP2, SFRP5, SIX3, SLC9A1, SLC11A1, STAT3, TRIP6, TSC2, ZIC1, NUP214, AKAP1, FZD7, DYRK2, RGS20, AKR1C3, TNFSF14, HDAC3, SEMA5A, RPL23, SLC9A3R1, ZFYVE9, AKAP6, LITAF, NUP155, IPO13, NUP93, KEAP1, NUTF2, APC2, TACC3, CREB3, CHERP, RBCK1, TXNIP, EDAR, SEC61B |
1392 | GO:0010977 | 0.01 | 2.34 | 11.56 | 18 | 31 | negative regulation of neuron projection development | ADCY6, ARF6, DPYSL3, LPAR1, EFNA1, EFEMP1, GAK, GFAP, GFI1, SPOCK1, VIM, CBFA2T2, BAG5, RAPGEF2, KIAA0319, CARM1, STMN2, CIT |
1393 | GO:0099565 | 0.00 | 2.33 | 16.08 | 25 | 43 | chemical synaptic transmission, postsynaptic | ABAT, ADRB2, TSPO, CHRNB2, CHRNB4, PTK2B, GABRA4, GABRA6, GLRA1, GLRA2, GRID2, GRIN2A, NTSR1, P2RX4, P2RY11, PRKCZ, RELN, PTEN, CX3CL1, SNCA, DGKI, S1PR2, NRXN1, RIMS2, EIF4A3 |
1394 | GO:1901861 | 0.01 | 2.33 | 11.57 | 18 | 31 | regulation of muscle tissue development | CAV3, CENPF, CXADR, DDX5, TSC22D3, FGF3, IGFBP5, KCNK2, SMAD3, S100B, SIX1, TP73, TWIST1, HDAC3, CTDP1, HDAC4, NR1D2, USP19 |
1395 | GO:0048041 | 0.02 | 2.33 | 11.58 | 18 | 31 | focal adhesion assembly | ACTN1, ACVRL1, ARHGAP6, BCL2, DAPK3, EFNA5, CTTN, PTK2B, LAMA5, PTEN, PTK2, SLC9A1, TRIP6, ARHGEF7, TAOK2, SLK, SORBS1, FERMT2 |
1396 | GO:0046034 | 0.00 | 2.32 | 21.26 | 33 | 57 | ATP metabolic process | AK1, AK2, AK4, AMPD2, ATP1A2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V0A1, ATP5O, BAD, COX4I1, COX8A, COX15, CTNS, HSPA8, LDHC, SDHC, TAZ, UQCRC1, UQCRC2, UQCRH, ATP5J2, SLC25A13, ATP5H, ATP5L |
1397 | GO:0021885 | 0.02 | 2.32 | 11.59 | 18 | 31 | forebrain cell migration | AXL, CX3CR1, DCX, EMX2, NRG1, OGDH, PEX13, RELN, PSEN1, RAC1, SRF, CNTN2, TNR, TYRO3, NRP1, SLIT2, SEMA3A, NRG3 |
1398 | GO:0038123 | 0.02 | 2.32 | 11.59 | 18 | 31 | toll-like receptor TLR1:TLR2 signaling pathway | BTK, CD36, CHUK, CREB1, ATF2, DUSP4, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK8, RPS6KA1, SKP1, UBB, CUL1, IKBKG, RIPK2 |
1399 | GO:0038124 | 0.02 | 2.32 | 11.59 | 18 | 31 | toll-like receptor TLR6:TLR2 signaling pathway | BTK, CD36, CHUK, CREB1, ATF2, DUSP4, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK8, RPS6KA1, SKP1, UBB, CUL1, IKBKG, RIPK2 |
1400 | GO:0090109 | 0.02 | 2.32 | 11.59 | 18 | 31 | regulation of cell-substrate junction assembly | ACVRL1, ARHGAP6, COL16A1, DAPK3, EFNA5, HRG, KDR, SMAD3, PTEN, PTK2, PTPRJ, RAC1, S100A10, SDC4, SLC9A1, TSC1, ITGB1BP1, SLK |
1401 | GO:1902533 | 0.00 | 2.32 | 32.60 | 51 | 90 | positive regulation of intracellular signal transduction | APOA1, ATM, ATR, CD3E, CD4, CD8A, CDKN2A, CNTF, COL3A1, CTF1, DDX5, GNAS, GSTM2, HIC1, HPX, HES1, IFNA2, IFNG, IL10, IL13, IL15, ISL1, P2RX3, P2RX4, P2RX5, PF4, PTGER4, RAC1, RHEB, SLC9A1, SLC12A1, SOS2, SOX11, WNT11, SHOC2, TNFRSF18, TNFRSF10A, HDAC3, TNFSF18, DGKI, CRLF1, GSTO1, AKAP6, EEF1E1, AKAP12, TNFSF15, TRDN, HEXIM1, RRAGA, COPS8, IL24 |
1402 | GO:0009416 | 0.00 | 2.32 | 54.27 | 84 | 146 | response to light stimulus | ABCA4, ABL2, ADRA1B, APOA1, APP, ATP1A2, ATP1A3, CCND1, BCL2, BCL3, OPN1SW, BRCA2, CACNB4, AKR1C4, CHRM1, CHRNB2, CIRBP, CLU, CLPS, CREB1, CTNS, DBH, DNM2, DRD3, DUSP1, ELK1, ERCC1, ERCC3, ERCC5, ERCC6, FEN1, GPC4, OPN1MW, GPC3, GNAQ, GNGT2, GPX1, GRIN2A, HMGN1, HMGCR, HRH1, HRH2, IL12B, ITGB1, JUND, KIT, KRAS, NTRK2, OGG1, PDC, PDE1B, PER1, SERPINB13, PRKAA1, MAPK8, RBM4, RBP1, RBP2, OPN1LW, RGR, RPE65, SDC2, SDC4, SGK1, SLC1A3, TROVE2, TRPC3, TULP1, TYR, USF1, XPA, COPS3, AKR1C3, SEMA5A, UNC119, USP2, DHRS3, CLOCK, SDC3, KIAA0101, NR2E3, GPC6, DEAF1, RRH |
1403 | GO:1903038 | 0.00 | 2.32 | 18.70 | 29 | 50 | negative regulation of leukocyte cell-cell adhesion | ANXA1, ASS1, BMP4, CBLB, CDKN2A, CTLA4, CYLD, ERBB2, HLX, IFNA2, IHH, IL2RA, IL10, IDO1, IRF1, PAWR, PRKAR1A, PTPN6, CCL21, CCL25, XCL1, SFTPD, SPN, TNFSF4, SCGB1A1, PDE5A, TNFSF18, SOCS6, GLMN |
1404 | GO:0031401 | 0.00 | 2.32 | 255.82 | 386 | 684 | positive regulation of protein modification process | ABL1, ABL2, ACVR1, ACVR2A, ACVR2B, ACVRL1, ADCY3, ADCY5, ADCY6, ADCY9, ADRA1B, ADRA2A, ADRB2, AGTR2, AKT2, ALK, ANG, ANGPT1, BIRC2, BIRC3, XIAP, ARAF, ARNT, ATM, ATP6AP1, AVP, AVPR2, BAX, CCND1, BCL2, BMI1, BMP1, BMP3, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, BRCA1, C3, CALM1, CALM3, CAMK2A, CAV2, CAV3, CCK, CCNB1, CCNC, CCND3, CCNH, CCNT1, CCNT2, CD3E, CD4, CD80, CD36, CD44, CD81, CDC20, CDC27, CDC42, CDK9, CDKN1A, CDKN2A, CENPE, CLU, CNTF, CREBL2, CRH, CRKL, CSF1R, CSF2RB, CSNK1D, CSPG4, CTF1, CTGF, DAB2, ACE, GADD45A, DNMT1, DNMT3B, HBEGF, DUSP5, DYRK1A, GPR183, LPAR1, EDN3, EDNRA, EFNA1, EFNA5, EMP2, EPHA7, EPHA8, ERBB2, EREG, ERCC6, ERN1, ESR1, F2, F2R, F2RL1, ACSL1, PTK2B, FGA, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FGG, FLT1, FLT3, FLT3LG, FLT4, FPR1, FSHR, FYN, GAS6, GCG, KAT2A, GDF9, GFRA2, GNG3, GOLGA2, GPLD1, GRB2, RAPGEF1, GRIN2A, GRM1, HIST1H1B, HCLS1, HGF, NRG1, UBE2K, HMGCR, HPX, HES1, DNAJB2, HSP90AB1, HTR2C, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF1R, IGF2, IGFBP3, IL1A, IL1B, IL2RA, IL12B, IL13, IL15, IL18, ILK, INHA, INS, IRAK1, IRAK2, ISL1, ITGA1, ITGA5, ITGB1, JARID2, JUN, KDR, KISS1, KIT, KRAS, LTF, SMAD3, SMAD7, MARK3, MAP3K5, KITLG, MAP3K11, PPP1R12A, NTF3, NTRK1, NTRK2, NTRK3, TNFRSF11B, P2RX7, P2RY1, PEBP1, PARK2, PAWR, PDE6G, PDE6H, ENPP2, PFN2, PIK3CB, PIM1, PPP5C, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCE, PRKD1, PRKCZ, EIF2AK2, RELN, PSAP, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTGER4, PTK2, PTPN1, PTPRA, RAC1, RAF1, RAP2A, RAP2B, RASA2, RPS3, RYK, S100A7, S100A12, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SDCBP, SHC1, STIL, SKP1, SLC11A1, SUMO3, SNCA, SOD1, SOS1, SOX2, SOX9, SPN, SREBF1, STK10, STK11, XCL2, ADAM17, TNFRSF1A, TNFRSF1B, TP73, TPD52L1, TRAF2, TTK, TNFRSF4, UBB, UBE2L3, UBE3A, UCN, VEGFB, VEGFC, VTN, WFS1, WNT1, WNT11, FZD5, AIMP2, ARHGEF5, FGF23, CDK2AP1, FZD4, FZD7, FZD8, BCAR3, CUL3, CUL1, OGT, IKBKG, CAMK1, MAPKAPK5, CDC14B, PDE5A, PEA15, CDC23, EED, RIPK1, ADAM9, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10B, TNFRSF10A, NRP1, HDAC3, KAT2B, CDC16, RPS6KA4, TNFSF18, UNC119, RGN, LATS1, ARHGEF2, VAPB, CRLF1, ITGB1BP1, GPR55, S1PR2, TAOK2, AKAP6, PSMF1, GDF15, BAG4, NRG2, TRAF4, CTR9, RAPGEF2, SLK, HDAC4, ATG13, RNF40, RB1CC1, ZEB2, PSMD6, OXSR1, TNFSF15, RBX1, ABI1, TOM1L1, RAD50, AKAP9, RASA4, SORBS3, TNK2, PSME3, PSMD14, ABCA7, ANAPC10, PIAS3, RAPGEF3, MAD2L2, STK25, SEMA4D, ATG7, ARL6IP5, ARFGEF1, NRG3, FRS3, RUVBL2, ARID5A, MALT1, JTB, COPS8, IL24, UBE2C, MAP4K5, CHEK2, FZD10 |
1405 | GO:0030216 | 0.01 | 2.31 | 14.19 | 22 | 38 | keratinocyte differentiation | JAG1, ALOX15B, ANXA1, DNASE1L2, DSP, EPHA2, EREG, FLG, RBPJ, S100A7, SRSF6, ST14, TSG101, MADCAM1, FOXN1, TP63, AKR1C3, ADAM9, SCEL, LATS1, TRIM16, TXNIP |
1406 | GO:0045582 | 0.01 | 2.31 | 14.21 | 22 | 38 | positive regulation of T cell differentiation | ANXA1, BAD, CD80, CD86, EGR3, HLX, IFNG, IHH, IL1B, IL2RA, IL12B, CD46, PRKCZ, RAG1, RARA, STAT5B, TNFSF4, AP3B1, TNFSF9, RIPK2, AP3D1, IKZF1 |
1407 | GO:0009892 | 0.00 | 2.31 | 22.23 | 35 | 63 | negative regulation of metabolic process | ACADL, ACADVL, APLP1, APOH, ATP1A1, BCL2, BCL2L1, BNIP3, CACNA1A, CCNC, CDA, COMT, LPAR1, EDNRA, GATA4, GOLGA2, GPLD1, GRM8, INSIG1, KIF25, PDE3B, PRKAA1, RPS19, SOD1, AKR1C3, DYNLL1, BECN1, AKAP6, FEZ2, RAPGEF2, TRAP1, ERLIN1, RRAGA, ERLIN2, WDR6 |
1408 | GO:0010976 | 0.00 | 2.31 | 29.11 | 45 | 78 | positive regulation of neuron projection development | ABL2, ARF1, BMP4, CNR1, DPYSL3, LPAR1, PTK2B, FYN, RAPGEF1, GRN, ARHGAP35, HGF, ITGA3, ITGB1, CAPRIN1, NTRK1, OPA1, P2RY2, PALM, PARK2, PCP4, SERPINF1, PRKCI, PRKD1, RELN, PSEN1, PTN, PTPRD, SGK1, SYT1, SYT4, CAMK1, KAT2B, CBFA2T2, NUMBL, ADAMTS1, RAPGEF2, RIMS2, CUL7, FIG4, KATNB1, BAIAP2, AVIL, STMN2, IL1RAPL1 |
1409 | GO:0007498 | 0.00 | 2.31 | 23.94 | 37 | 64 | mesoderm development | ACVR1, ACVR2A, ACVR2B, BMP4, BMPR1A, BMPR2, BTK, EPHA2, EXT1, EXT2, EYA1, EYA2, HCK, ITGA3, ITGB1, ITGB4, SMAD1, SMAD3, OVOL1, PRKAR1A, RPL38, SNAI1, SRF, TAL1, TSPY1, KDM6A, WNT11, ZIC2, HMGA2, ITGA8, TP63, CHRD, KLF4, CER1, HAND1, IKZF1, CITED2 |
1410 | GO:0051340 | 0.03 | 2.30 | 9.69 | 15 | 26 | regulation of ligase activity | ABL1, ATM, BUB1B, CDKN2A, CENPF, DUSP1, LIMK1, SMAD7, PSEN1, TTK, ZNF207, RGN, ZW10, BAG5, MAD2L2 |
1411 | GO:0050848 | 0.00 | 2.30 | 16.83 | 26 | 45 | regulation of calcium-mediated signaling | CALM1, CALM3, CASQ2, CD3E, CD4, CD8A, RCAN1, PTK2B, GSTM2, NRG1, HRC, IGF1, ITPR1, P2RX3, P2RX4, P2RX5, PDE4D, PLN, SLC9A1, SLC12A1, RGN, GSTO1, AKAP6, RCAN2, TRDN, RCAN3 |
1412 | GO:0002682 | 0.00 | 2.30 | 46.75 | 73 | 131 | regulation of immune system process | ANXA5, APCS, ARF1, BGLAP, CDK6, AP1S1, AP2S1, COX8A, CLDN7, ACE, TSC22D3, EIF2S1, STOM, FCGR3B, FSHB, FSHR, SLC37A4, GABPA, GABRA5, IFIT1, KCNQ1, KDR, MDH1, NTHL1, ORM2, PCBP2, PDK4, PEX13, SERPINB10, PPM1B, EIF2AK2, SCN1A, CCL25, SLC1A3, SNRPD1, SOX9, STK10, ZNF189, CHAF1B, HIST1H4I, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, INPP4B, AP1S2, AP1M1, HIST1H3F, GPR55, SLIT2, CHST3, CTR9, NUP93, PHYHIP, IST1, FGFBP1, AP1M2, LRRC17, FSTL3, TRIM38, GAS2L1, TRAF3IP2, TOB2 |
1413 | GO:0050776 | 0.00 | 2.30 | 25.03 | 39 | 69 | regulation of immune response | CD8A, CD8B, CD37, CD81, CDH1, COL1A1, COL17A1, CXADR, ICAM1, ICAM4, IFNA5, IFNA13, IFNA17, IFNA21, IFNGR1, ITGA4, ITGB1, KLRB1, KLRD1, SMAD3, CD200, PTPN1, RAC2, SELL, SFTPD, STAT1, STAT2, STXBP2, TYROBP, SUMO1, VCAM1, MADCAM1, SOCS3, CLEC2B, CD96, CXCL13, CD300C, CD160, CDC37 |
1414 | GO:0072376 | 0.03 | 2.30 | 9.70 | 15 | 26 | protein activation cascade | C1QA, C1QB, C1QC, C1S, C3, C7, CD59, CLU, CR2, FCN2, CFHR1, KRT1, CD46, CFP, VTN |
1415 | GO:0045619 | 0.00 | 2.30 | 31.79 | 49 | 85 | regulation of lymphocyte differentiation | ANXA1, AXL, BAD, PRDM1, BMP4, BTK, CAMK4, CD28, CD80, CD86, CDKN2A, CTLA4, CYLD, EGR3, ERBB2, FLT3, FLT3LG, GAS6, HLX, IFNA2, IFNG, IHH, IL1B, IL2RA, IL12B, IL15, INHA, IRF1, CD46, PRKCZ, PTPN6, RAG1, RARA, SOD1, SOS1, SOS2, STAT5B, ZEB1, TNFSF4, FOXN1, AP3B1, TNFSF9, RIPK2, AP3D1, TNFSF18, SOX13, RNF41, IKZF1, SPINK5 |
1416 | GO:0045995 | 0.00 | 2.29 | 19.45 | 30 | 52 | regulation of embryonic development | APOA1, BMP4, BMPR1A, CDX1, CDX2, COL5A2, E4F1, FZD2, FOXA2, HES1, IGF1, IL1RN, LAMA3, LAMA4, LAMA5, OTX2, PAX3, PRKACB, SIX1, SNAI1, NR2C2, TULP3, WNT1, WNT2, WNT2B, FZD7, KLF4, RBM19, SEC24B, DMRT2 |
1417 | GO:0048584 | 0.00 | 2.29 | 35.01 | 55 | 100 | positive regulation of response to stimulus | ADAM10, AGTR1, ALB, APOH, BNIP3L, BRCA1, CD6, S1PR1, EYA3, UTS2R, CXCL1, CXCL3, HMGA1, HSPB1, IL17A, INSL3, KCNK2, KLKB1, MGMT, ATXN3, PAFAH1B2, SERPINE1, PCNA, PENK, PF4V1, PIP4K2A, RAC2, RREB1, CXCL6, CXCL5, SETMAR, SGTA, SNCA, TAC1, NR2C2, TRPC3, TRPM2, UCN, USF1, VEGFC, SCG2, EPM2A, HMGA2, PIK3R3, USP13, RNF8, RGN, IL1RL1, SLIT2, ATG5, CXCL14, CLOCK, CREB3, ATG7, CXCL13 |
1418 | GO:0010646 | 0.00 | 2.29 | 18.99 | 30 | 55 | regulation of cell communication | ACTL6A, ATP1A2, ATP2B2, ATP6V0A1, CDC20, CSNK2A2, CTSK, CXADR, EGR2, KAT2A, HRH1, HRH2, KCNJ10, PFN2, SEPT5, RAB5A, RARA, RYR2, STAR, SYN1, U2AF1, ZBTB17, SYN3, RUVBL1, RAB11A, RAB33A, RIN1, SNCAIP, BAIAP2, CPLX2 |
1419 | GO:0002294 | 0.03 | 2.29 | 9.72 | 15 | 26 | CD4-positive, alpha-beta T cell differentiation involved in immune response | ANXA1, BCL3, CD80, CD86, HLX, IFNG, IL12B, PRKCZ, PTGER4, RARA, RELB, STAT6, TNFSF4, RIPK2, TNFSF18 |
1420 | GO:0006369 | 0.03 | 2.29 | 9.72 | 15 | 26 | termination of RNA polymerase II transcription | CSTF3, MAZ, SRSF1, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SNRPE, SNRPF, U2AF1, SRSF9, RBM8A, PAPOLA, RNPS1 |
1421 | GO:0044786 | 0.03 | 2.29 | 9.72 | 15 | 26 | cell cycle DNA replication | ATRX, FEN1, PCNA, PRIM2, UPF1, RFC3, RFC4, RFC5, RPA2, RPA3, SMC1A, SMC3, GINS1, STAG2, CHEK2 |
1422 | GO:0046637 | 0.03 | 2.29 | 9.72 | 15 | 26 | regulation of alpha-beta T cell differentiation | ANXA1, CD80, CD86, HLX, IFNG, IHH, IL12B, PRKCZ, RARA, TNFSF4, AP3B1, RIPK2, AP3D1, TNFSF18, IKZF1 |
1423 | GO:0048846 | 0.03 | 2.29 | 9.72 | 15 | 26 | axon extension involved in axon guidance | BMPR2, SEMA3F, SLIT3, SEMA3B, NRP2, NRP1, SEMA5A, SLIT2, SEMA3E, SEMA3A, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B |
1424 | GO:1901998 | 0.03 | 2.29 | 9.72 | 15 | 26 | toxin transport | ATP6V0A1, BNIP3, CASP1, DNM1, HRH2, MEP1B, SLC22A3, CCT3, NRP1, COPB2, ABCG1, CCT7, CCT4, CCT2, CCT6B |
1425 | GO:0031347 | 0.00 | 2.29 | 118.63 | 181 | 319 | regulation of defense response | A2M, ADAR, ADRB2, AGTR1, AHSG, ANXA1, APCS, XIAP, APOA1, BCR, BTK, SERPING1, C3, C7, CALM1, CALM3, CASP4, CASP5, CD6, CD86, CD36, CD59, CHUK, CNR1, CNR2, CREB1, ATF2, CRH, CTSK, CX3CR1, CYBA, CYLD, DMBT1, DUSP4, EDNRA, ELK1, EP300, EREG, ETS1, F2RL1, FCER1G, FGR, GFI1, GHSR, FFAR3, GPX1, UBE2K, HPX, HSP90AB1, ICAM2, ICAM3, IFI16, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNGR1, IGF2, IL1B, IL1R1, IL10, IL17A, IL18, IDO1, INS, IRAK1, IRAK2, IRF1, ISL1, ITGAM, ITPR1, ITPR2, JUN, KLKB1, KRAS, KRT1, LTF, SMAD3, CD46, SERPINE1, SERPINF1, PENK, PER1, CFP, PGC, SERPINB9, PIK3C3, PPP2R5D, PPP3R1, PRKACB, PRKACG, PRKCD, PRKCE, MAPK8, PROC, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTGER4, PTGIS, PTPN1, PTPN6, PVR, RAF1, RELB, RPS6KA1, RPS19, S100A8, S100A9, S100A12, SERPINB4, CCL24, XCL1, CX3CL1, SELE, SKP1, STAT1, STAT5B, XCL2, TAC1, TNFAIP6, TNFRSF1A, TNFRSF1B, HSP90B1, TNFSF4, TYRO3, UBB, UBE2D2, SUMO1, UCN, SCGB1A1, NR1H2, VAV1, VTN, CUL1, IKBKG, VAMP8, RIPK1, RIPK2, TNFSF18, SOCS3, UBA3, IL1RL1, KLF4, SLIT2, PSMF1, CLOCK, PSMD6, TRIL, NR1H4, NR1D2, PSME3, CALCRL, PSMD14, TNIP1, CNPY3, MALT1, TRAFD1, SPINK5, CDC37 |
1426 | GO:0044270 | 0.02 | 2.28 | 10.35 | 16 | 28 | cellular nitrogen compound catabolic process | ACADL, AMBP, AOX1, BHMT, BLVRA, BLVRB, CCBL1, CYP3A4, DPEP1, HAL, HNMT, IDO1, ALDH6A1, TST, KYNU, ALDH1L1 |
1427 | GO:0006109 | 0.00 | 2.28 | 32.54 | 50 | 87 | regulation of carbohydrate metabolic process | ACACB, ADRA1B, AKT2, ARNT, BAD, PTK2B, GCG, GCGR, KAT2A, GOLGA2, GPD1, GPLD1, HIF1A, FOXA2, HRH1, IGF1, IGF2, IGFBP3, IGFBP5, IL15, INS, KHK, NTSR1, P2RX7, P2RY1, PARK2, PDK4, PFKFB1, PFKFB2, PGAM1, PGAM2, PRKAA1, PRKAG1, PRKCE, PTAFR, PTGER4, RANBP2, SNCA, STAT3, DYRK2, OGT, KAT2B, RGN, TMEM59, HDAC4, EPM2AIP1, NR1H4, ARFGEF1, SORBS1, ARPP19 |
1428 | GO:0006612 | 0.00 | 2.28 | 43.01 | 66 | 115 | protein targeting to membrane | AKT2, BSG, STOM, ERBB2, FAU, GAS6, GDI1, KCNE1, RPL10A, PALM, PRKCI, PEX19, PEX5, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, SDCBP, SRP9, SRP14, SRP19, SRP68, SSR1, OGT, RPL14, ITGB1BP1, TAOK2, RPL23, PEX16, C2CD5, SEC61B, TMED2, RPL35, SEC63 |
1429 | GO:0042308 | 0.01 | 2.28 | 12.34 | 19 | 33 | negative regulation of protein import into nucleus | ANGPT1, CD36, CYLD, GAS6, IL10, TONSL, PPM1A, PPM1B, SFRP5, TRIP6, AKAP1, DYRK2, TNFSF14, SLC9A3R1, LITAF, KEAP1, APC2, TACC3, CREB3 |
1430 | GO:0051881 | 0.01 | 2.28 | 12.34 | 19 | 33 | regulation of mitochondrial membrane potential | ABL1, ALOX12, BAD, BAX, BCL2, BCL2L1, TSPO, CASP1, CCK, CDKN2A, DCN, KDR, P2RX7, PARK2, PYCR1, SOD1, UBB, ARL6IP5, PRDX3 |
1431 | GO:1903391 | 0.01 | 2.28 | 12.34 | 19 | 33 | regulation of adherens junction organization | ACVRL1, ARHGAP6, COL16A1, DAPK3, EFNA5, HRG, KDR, SMAD3, PTEN, PTK2, PTPRJ, RAC1, RDX, S100A10, SDC4, SLC9A1, TSC1, ITGB1BP1, SLK |
1432 | GO:0002274 | 0.00 | 2.28 | 17.54 | 27 | 47 | myeloid leukocyte activation | ADAM10, BPI, CAMK4, CD86, CD37, CLU, ACKR2, CNR1, CNR2, FLT3LG, RBPJ, IL10, JUN, PRKCD, PSEN1, PTPRE, RELB, S100A12, CX3CL1, SLC11A1, SNCA, TRPV1, TNFSF9, ADAM9, IL1RL1, DHRS2, PRG3 |
1433 | GO:0019054 | 0.01 | 2.27 | 14.96 | 23 | 40 | modulation by virus of host process | BAD, BCL2L1, CD4, KPNA1, KPNA2, KPNA3, KPNA4, KPNA5, NTRK3, NUP88, NUP98, PARK2, EIF2AK2, RANBP2, NUP214, AAAS, VAPB, NUP155, NUP93, BCL2L11, ATG7, NUP50, NUPL2 |
1434 | GO:0046483 | 0.00 | 2.27 | 16.51 | 26 | 48 | heterocycle metabolic process | ALOX12, BCHE, BTD, CCBL1, CYP2A6, CYP3A4, SARDH, DPEP1, GOT2, GRIN2A, HAL, HLCS, HNMT, P4HA1, PAH, SHMT2, SLC34A1, SRD5A1, STAR, GGH, VNN2, SLC5A6, P4HA2, CRTAP, PRDX4, ALDH1L1 |
1435 | GO:0034333 | 0.00 | 2.27 | 20.20 | 31 | 54 | adherens junction assembly | ACTN1, ACVRL1, ARHGAP6, BCL2, COL16A1, DAPK3, EFNA5, CTTN, PTK2B, HRG, KDR, LAMA5, SMAD3, SMAD7, PTEN, PTK2, PTPRJ, RAC1, S100A10, SDC4, SLC9A1, TBCD, TRIP6, TSC1, ARHGEF7, ITGB1BP1, TAOK2, SLK, RAMP2, SORBS1, FERMT2 |
1436 | GO:0048729 | 0.01 | 2.26 | 16.22 | 25 | 44 | tissue morphogenesis | ACTG2, BMPR1A, BMPR2, EXT2, EYA2, GNAT2, ITGA3, ITGB1, ITGB4, SMAD1, PRKAR1A, PTN, PTPRM, RPGR, RPE65, RS1, SIX3, STC1, TAL1, HMGA2, ITGA8, CHRD, SLC4A7, IRX5, IKZF1 |
1437 | GO:0006954 | 0.00 | 2.26 | 64.04 | 98 | 173 | inflammatory response | PARP4, AGTR2, ANXA1, AOX1, BIRC2, BIRC3, XIAP, AXL, BMP6, CAMK4, CASP4, CASP5, TNFRSF8, ADGRE5, CDO1, CHUK, CCR3, CCR5, ACKR2, LTB4R, CRH, CRHBP, CSF1R, CYBA, CYBB, ECM1, S1PR3, F2RL1, XCR1, CXCL1, CXCL3, HCK, HRH1, IFI16, IFNA2, IL1R1, IL1RAP, IL13, IRAK2, KIT, KNG1, LTA4H, CD180, SMAD1, MEP1B, NTRK2, OLR1, TNFRSF11B, P2RX1, P2RX7, PER1, PF4, PF4V1, PIK3CB, PRKD1, PRKCQ, PRKCZ, PSMA6, PTAFR, PTGDR, PTGS1, RAC1, RELB, RXRA, CCL20, CCL21, CCL22, CCL25, CXCL6, CXCL5, SELE, SELP, SLC11A1, SP100, TP73, TNFRSF4, UCN, SCGB1A1, SCG2, ATRN, TPST1, IKBKG, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, IL18RAP, RPS6KA4, THEMIS2, HDAC4, TRIL, NR1D2, TSPAN2, CHST4, CXCR6, IL24 |
1438 | GO:0048667 | 0.00 | 2.26 | 153.52 | 232 | 412 | cell morphogenesis involved in neuron differentiation | ABL1, ACTB, ACTG1, ADAM10, ANGPT1, APP, ARAF, ARHGAP4, ATOH1, ATP2B2, ADGRB1, BCL2, BMPR2, CACNB3, CACNB4, CALM1, CALM3, CAMK2A, CCK, CD72, CDC42, CHN1, AP2S1, CLTA, CNP, COL3A1, COL4A3, COL4A5, COL5A2, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2RB, CSNK2A1, CSNK2A2, DCC, DLG3, DLX5, DNM1, DNM2, DPYSL3, EPYC, HBEGF, ECM2, DUSP5, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EPHA2, CTTN, EPHA1, EPHA5, EPHA7, EPHA8, ERBB2, EREG, ETV4, EXT1, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, GDI1, GFRA1, GOLGA4, GRB2, GRIN2A, ARHGAP35, NRG1, HES1, HSPA8, HSP90AA1, HSP90AB1, IFRD1, IL2RA, ISL1, ITGA1, ITGA5, ITGA9, ITGAV, KIF5A, KIT, KRAS, ABLIM1, LIMK1, MARK3, KITLG, NRCAM, NRTN, NTF3, NTRK1, NTRK2, NTRK3, NTN3, OGN, OMG, OTX2, PEBP1, PPP5C, PRKCQ, PSPN, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTK2, PTPRA, PTPRM, RAC2, RAF1, RASA2, RB1, RNF6, RPL24, RPS6KA1, RYK, S100A6, S100B, SCN5A, SDCBP, SEMA3F, SHC1, SIAH1, SLC1A3, SLIT3, SOD1, SOS1, SOS2, SPAST, SRF, STXBP1, CNTN2, TBCE, TNR, TOP2B, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, CLRN1, SEMA3B, FGF23, RND2, USP9X, CUL3, CNTNAP1, UNC5C, NUMB, PEA15, RAB11A, NRP2, NRP1, ARHGEF7, PHOX2B, RPS6KA4, KALRN, SEMA5A, ARHGEF1, SLIT2, SLC9A3R1, NRXN3, NRXN1, PSMF1, NRG2, AATK, FEZ2, SEMA3E, IST1, ARHGEF11, FARP2, PSMD6, RBX1, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, PSME3, PSMD14, SPON2, SEC24B, VAV3, SLC9A6, CAP1, STK25, SEMA6C, SEMA6B, SEMA4F, SEMA4B, ATG7, ARPC1A, DPYSL4, TBR1, CHL1, FRS3, RAB10, AFG3L2, VAX1 |
1439 | GO:0001508 | 0.01 | 2.26 | 13.03 | 20 | 35 | action potential | ATP1A1, ATP1A2, CACNA1A, CACNA1B, CACNB4, CHRNB4, GLRA1, GNAQ, KCNC2, KCNE1, KCNH2, KCNQ1, NRCAM, SCN4B, CNTNAP1, AKAP7, AKAP6, NUP155, KCNE2, HCN4 |
1440 | GO:0002764 | 0.00 | 2.26 | 130.15 | 197 | 348 | immune response-regulating signaling pathway | ABL1, ACTB, ACTG1, ANGPT1, BIRC2, BIRC3, XIAP, ARAF, BAD, BAX, BCL2, BLK, BTK, CACNB3, CACNB4, CALM1, CALM3, CAMK2A, CASP9, CBLB, CD3D, CD3E, CD3G, CD4, CD28, CD80, CD86, CD36, CD38, CD79B, CDC42, CDKN1A, CHUK, CR2, CREB1, ATF2, CSF2RB, CTLA4, CTSH, CTSK, CYBA, CYLD, DMBT1, HBEGF, DUSP4, DUSP5, ELK1, EP300, ERBB2, EREG, F2RL1, FCER1G, FCGR1A, FCGR1B, FCGRT, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FGR, FYB, FYN, GFI1, GPLD1, GRB2, GRIN2A, HCK, NRG1, HLA-DQA1, NR4A1, HSP90AA1, HSP90AB1, ICAM2, ICAM3, IL1B, IL2RA, IRAK1, IRAK2, IRF1, ITGAM, ITPR1, ITPR2, JUN, KCNN4, KIT, KRAS, LIMK1, LTF, MARK3, KITLG, FOXO4, PEBP1, PAWR, PDE4B, PDE4D, PIGR, PIK3C3, PIK3CB, PPP2R5D, PPP3R1, PPP5C, PRKACB, PRKACG, PRKCD, PRKCE, PRKCQ, MAPK8, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, PTPN6, PTPRA, PTPRJ, RAC1, RAF1, RASA2, RELB, RPS6KA1, RPS6KB2, SEC14L1, SHC1, SKP1, SOS1, STK11, TNFAIP3, HSP90B1, TSC2, TYRO3, UBB, UBE2D2, VAV1, LAT2, FGF23, CUL3, CUL1, IKBKG, PEA15, RIPK1, RIPK2, UBA3, GRAP2, THEMIS2, PSMF1, NRG2, BCAR1, RAPGEF2, ELMO1, GAB2, PSMD6, TRIL, NR1H4, RBX1, ABI1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, WASF2, PSME3, PSMD14, TNIP1, VAV3, BAIAP2, ARPC1A, RBCK1, CNPY3, FRS3, MALT1, BTN3A1 |
1441 | GO:0044282 | 0.00 | 2.25 | 81.53 | 124 | 218 | small molecule catabolic process | ABAT, ACAA1, ACACB, ACADL, ACADM, ACADS, ACADSB, ACADVL, ADH5, AGXT, AHCY, AKT2, ABCD1, ALDH2, ALDH9A1, ALDOB, ALDOC, AMT, ARG1, ASL, AUH, BAD, BCAT1, BCKDHA, CBS, CCBL1, CDO1, CNR1, CPT1B, CPT2, CRAT, CRYM, CTH, CYP24A1, DBT, DECR1, ECH1, ENO2, ENO3, ESD, FAAH, FUT6, FUT8, GAD1, GAD2, GALE, GALK1, GAPDH, GK2, GLB1, GLDC, GLS, GLUD1, GLUL, GOT1, GOT2, GPD2, GPT, GSTZ1, HSD17B10, HAL, HMGCL, HNMT, IDUA, IMPA1, IDO1, INPP1, IVD, KHK, LDHA, LIPC, LIPE, ALDH6A1, NTSR1, OAT, OGDH, OTC, OXCT1, PAH, ENPP2, PEX7, PEX13, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PGM1, PPP2R5D, PRKCD, PTEN, ABCD3, QDPR, RENBP, RPE, SHMT1, SORD, SUOX, TAT, TST, TWIST1, FGF23, ACOX2, ACOX3, BBOX1, DDO, AKR1C3, ALDH4A1, SYNJ1, KYNU, SNX17, XYLB, ACOT8, AASS, BCKDK, AKR1A1, ECI2, SLC25A17, FUT9, ALDH1L1, SDS, SLC27A4, SLC27A2, HIBADH |
1442 | GO:0071822 | 0.00 | 2.25 | 45.99 | 71 | 128 | protein complex subunit organization | BNIP3, CHD3, DAPK3, DYNC1H1, DSP, EIF5A, EML1, ETF1, FAU, AGFG1, KRT9, RPL10A, PCM1, RAN, UPF1, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, STIL, SLN, TTK, VIM, SMC1A, RPL14, SMC3, RPL23, CRIPT, SLK, CKAP5, IST1, DNAJC6, SMC4, APC2, KATNB1, TRDN, TACC3, TACC2, GAS2L1, DCTN6, KIF2C, RPL35 |
1443 | GO:0006414 | 0.00 | 2.25 | 34.03 | 52 | 91 | translational elongation | AARS, DIO2, EEF1A2, EEF1B2, EEF2, EIF5A, FAU, RPL10A, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, SRP9, TUFM, RPL14, RPL23, EEF1E1, GTPBP1, EIF4A3, USP16, RPL35 |
1444 | GO:0016265 | 0.00 | 2.25 | 410.29 | 601 | 1097 | death | AARS, ABL1, ABL2, ACTN1, ACVR1, ADAR, ADD1, ADM, PARP4, ADRB2, AGTR2, AKT2, ALB, ALDH1A3, ALK, ALOX12, ALOX15B, ALX3, ANGPT1, ANXA1, ANXA5, ANXA6, APAF1, BIRC2, BIRC3, XIAP, BIRC5, APLP1, APOH, APP, ARAF, ARF6, ARHGAP4, ASCL1, ATF4, ATM, ATOH1, ATP2A1, AVP, AXL, BAD, BAG1, BARD1, BAX, BCL2, BCL2A1, BCL2L1, BCL3, BDKRB2, BID, BLK, BMP1, BMP3, BMP4, BMP6, BMP8B, BMPR2, BNIP2, BNIP3, BNIP3L, BOK, BRCA1, BRCA2, BTG1, BTK, BUB1B, TSPO, CACNA1A, CAMK2A, CASP1, CASP4, CASP5, CASP6, CASP9, CAT, CBL, CCK, KRIT1, CD3E, CD3G, CD5, CD28, TNFRSF8, TNFSF8, CD38, CD44, CD59, CD70, CDK11B, CDC42, CDH1, CDK4, CDKN1A, CDKN2A, CLC, CLU, CNR1, CNTF, COL4A3, COMP, CLDN7, CREB1, ATF2, CRH, CRYBA1, CSE1L, CSF1R, CSNK2A1, CSNK2A2, CTGF, CTH, CTLA4, CTNNA1, CTSH, CTSV, CX3CR1, CYLD, DAB2, DAD1, DAPK3, BRINP1, DBH, DCC, GADD45A, DDIT3, DDX5, DFFA, DFNA5, DHCR24, DNASE1, DNASE1L3, DNASE2, DNM2, DPEP1, TSC22D3, DSP, DUSP1, E2F2, LPAR1, EDNRA, EEF1A2, EGR3, EIF2S1, EPHA2, EIF4G2, EIF5A, ELK1, EMP1, EMP2, EMP3, CTTN, EP300, EPHA7, EPHB1, ERCC3, ERCC5, ERCC6, ERN1, ESR1, ETS1, EYA1, EYA2, F2R, F3, PTK2B, FAP, FCER1G, FGA, FGD1, FGF4, FGFR3, FGG, FLT3, FLT4, FYN, GABRA5, GAPDH, GAS1, GAS2, GAS6, GATA6, GCG, GDF9, B4GALT1, GNB1, GNGT1, SFN, GPLD1, GPX1, GRID2, GRIN2A, GRINA, GZMH, HBA2, HCK, HCLS1, HGF, NRG1, HIC1, HIF1A, HIP1, UBE2K, HMGCR, HP, HRG, PRMT2, HSPA9, HSPB1, HSP90AB1, IAPP, ICAM1, IFI16, IFIT3, IFNA2, IFNG, IGBP1, IGF1, IGF1R, IGFBP3, IHH, IL1A, IL1B, IL2RA, IL10, IL12B, IL13, IL17A, ILK, IDO1, ING2, INHA, INS, INSL3, IRAK1, IRF1, IRF5, ISL1, ITGA1, ITGA5, ITGAV, ITGB1, ITPR1, JUN, JUND, KCNJ1, KCNK2, KDR, KIT, KNG1, KPNA1, KRAS, KRT18, LDHA, LTF, EPCAM, SMAD3, SMAD6, MAL, MAP3K5, MEOX2, KITLG, MGMT, MAP3K11, CITED1, SLC11A2, YBX1, NTF3, NTF4, NTRK1, NTRK2, NTRK3, NTSR1, OGG1, OLR1, OPA1, TNFRSF11B, P2RX1, P2RX4, P2RX7, PA2G4, PAEP, PAFAH2, SERPINE1, SERPINB2, PARK2, PAWR, PAX3, PAX4, PCP4, PDE3A, PDE1B, PDK4, SERPINF1, PF4, SERPINB9, SERPINB13, PIM1, PPID, PPP2CB, PPP2R1A, PPP2R1B, PPP3R1, PPP5C, PRKAA1, PRKCD, PRKCE, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK8, EIF2AK2, PROC, PSAP, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTGIS, PTK2, PTN, PTPN1, PTPN6, PTPRH, PYCR1, PYGL, RAC1, RAD21, RAF1, RAG1, RARA, RARB, RB1, DPF2, REST, RPS3, RPS3A, RPS6, RPS6KA1, RPS6KB1, RXRA, RYR2, SORT1, S100A8, S100A9, S100B, SATB1, SCN2A, CCL21, CX3CL1, SET, SFPQ, SFRP4, SFRP5, SRSF6, SGK1, SHB, SIAH1, ST6GAL1, STIL, SIX1, SIX3, SLC9A1, SLIT3, SNAI1, SNCB, SNCA, SOD1, SOD2, SON, SOS1, SOS2, SOX2, SOX9, SOX10, SOX11, SP100, SPN, SRPK2, STAR, STAT1, STAT3, STAT5B, AURKA, STK10, STK11, STXBP1, SUPV3L1, ADAM17, TMF1, TNFAIP3, TNFRSF1A, TNFRSF1B, TOP1, TOP2A, TP73, TPD52L1, TPT1, HSP90B1, TRAF1, TRAF2, TRPM2, TSC1, TWIST1, TNFRSF4, TYRO3, UBB, UCN, UNG, VAV1, VDAC2, VEGFB, VIL1, VIM, VIP, TRPV1, WFS1, WNT11, XPA, XRCC2, YWHAZ, ZNF16, PAX8, FZD5, SCG2, AIMP2, FOSL1, HMGA2, DPF1, PICALM, SRPX, NSMAF, DYRK2, CUL4A, CUL3, CUL2, CUL1, KLF11, OGT, IKBKG, CBX4, API5, RGS20, TP63, UNC5C, AKR1C3, DYNLL1, BECN1, PEA15, TRADD, URI1, RIPK1, CRADD, HRK, TNFSF14, TNFSF10, TNFSF9, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, TRIM24, NRP1, CFLAR, WISP3, WISP1, HDAC3, TSC22D1, ALDH1A2, ARHGEF7, TAX1BP1, TNFSF18, KALRN, SOCS3, SEMA5A, RGN, LATS1, AIFM1, RABEP1, ARHGEF2, AURKB, CRLF1, STK17B, STK17A, BCL7C, BCL7B, KLF4, TAOK2, SLIT2, SLC9A3R1, EIF2AK3, ARHGEF6, ATG5, PSMF1, SLC4A7, LITAF, GDF15, EEF1E1, BAG5, BAG4, BAG3, EI24, BCAR1, TRAF4, AATK, SNCAIP, RAPGEF2, SLK, HDAC4, BCLAF1, KIAA0141, RB1CC1, ARHGEF11, ARHGEF17, ELMO1, PSMD6, OXSR1, TNFSF15, NR1H4, CASP8AP2, HDAC6, PDCD6IP, PDCD6, BCL2L10, BCL2L11, PDCD7, SGK2, FEM1B, TRAP1, RNF41, PSME3, DHRS2, TRIM13, PSMD14, ZNF443, RAMP2, SIGMAR1, SAP18, SMNDC1, TRAIP, KATNB1, CITED2, SEMA3A, RAPGEF3, ACAA2, VAV3, CREB3, STK25, SEMA4D, ATG7, ARL6IP5, DPYSL4, SIVA1, ERN2, RBCK1, STAMBP, IVNS1ABP, TXNIP, RRAGA, CHL1, TRAF3IP2, ZMYND11, GJB6, PROKR1, MALT1, JTB, EDAR, RNPS1, PRDX3, SERINC3, YWHAQ, IL24, PIM2, CAPN10, CORO1A, MAP4K5, CHEK2, AKAP13, DDX20 |
1445 | GO:0019886 | 0.00 | 2.24 | 20.94 | 32 | 56 | antigen processing and presentation of exogenous peptide antigen via MHC class II | ARF1, CANX, CENPE, AP1S1, AP2S1, CLTA, CTSD, CTSE, CTSV, DYNC1H1, DYNC1I1, DYNC1I2, DNM2, FCER1G, HLA-DQA1, KIF5A, KLC1, RAB7A, DYNLL1, CTSF, AP1S2, AP1M1, KIF3B, AP1M2, ACTR1B, SEC24B, IFI30, SEC23A, DCTN6, SEC24A, KIF2C, KIF3A |
1446 | GO:0042060 | 0.00 | 2.24 | 21.41 | 33 | 59 | wound healing | ACVRL1, BMP4, CAV3, CCNB1, CDH3, DCN, DRD5, DSP, ENO3, ERBB2, EREG, FGF7, NRG1, IFRD1, IL1B, INS, ITGA9, P2RY2, S100A8, SCNN1B, CCL20, SDC2, SDC4, SLC11A1, SOX2, SPRR3, ADAM17, DYSF, FZD7, ADAM15, CFLAR, SYT7, IL24 |
1447 | GO:0006611 | 0.03 | 2.24 | 10.46 | 16 | 28 | protein export from nucleus | ADAR, BARD1, CDKN2A, CSE1L, EGR2, EIF5A, HSPA9, NUP88, RAN, RANGAP1, SP100, STYX, NUP214, NUTF2, AHCYL1, NUPL2 |
1448 | GO:0032755 | 0.03 | 2.24 | 10.46 | 16 | 28 | positive regulation of interleukin-6 production | CD36, CYBA, F2R, F2RL1, FCER1G, IL17A, ISL1, P2RX7, PAEP, TWIST1, TNFSF4, UCN, TNFSF9, RIPK2, ARHGEF2, SPON2 |
1449 | GO:0001658 | 0.01 | 2.24 | 13.09 | 20 | 35 | branching involved in ureteric bud morphogenesis | AGTR2, BCL2, BMP4, CD44, EYA1, GPC3, HOXD11, ILK, LAMA5, TACSTD2, CITED1, PBX1, PSPN, SALL1, SIX1, SOX9, WNT1, WNT2B, PAX8, DCHS1 |
1450 | GO:0035666 | 0.01 | 2.24 | 13.09 | 20 | 35 | TRIF-dependent toll-like receptor signaling pathway | BIRC2, BIRC3, CHUK, CREB1, ATF2, DUSP4, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK8, RPS6KA1, SKP1, UBB, UBE2D2, CUL1, IKBKG, RIPK1, RIPK2 |
1451 | GO:1903725 | 0.01 | 2.24 | 13.09 | 20 | 35 | regulation of phospholipid metabolic process | ARF1, CD81, CDC42, EPHA8, ACSL3, PTK2B, FGFR3, FGR, FLT1, FLT3, HTR2C, IDH1, KIT, PRKCD, PTK2, RAC1, CCL21, PIK3R3, KLF4, VAV3 |
1452 | GO:2000026 | 0.00 | 2.24 | 108.18 | 165 | 299 | regulation of multicellular organismal development | ACACB, ACVR1, ACVR2A, ACVR2B, ADM, AHSG, ANGPT2, ANXA1, ANXA3, APCS, APOH, KLK3, ARHGDIB, ARNT, ATP6AP1, AXL, BGLAP, PRDM1, BRCA1, BRCA2, BTK, C1QC, C3, CA2, CAMK4, CBLB, KRIT1, CD3E, CD28, CD80, CD86, CDK6, CDKN2A, CLC, CCR3, COL1A1, COL4A3, CSF1R, CTH, CTLA4, CTSH, CYLD, DCN, ACE, DDIT3, ECM1, S1PR1, EGR3, EPHA2, EMP2, EPHA1, ERBB2, ETS1, F3, FLT1, FLT3, FLT3LG, FSHB, FSHR, NR5A1, GABPA, GAS6, GDF9, GNAS, UTS2R, GPX1, GTF2I, HCLS1, HHEX, HLX, HRG, HSPB1, IFNA2, IL1A, IL2RA, IL10, IL12B, IL15, IL17A, IDO1, INHA, IRF1, ITGA5, JUN, KRT1, LTF, SMAD7, CD46, FOXO4, OMD, P2RX7, SERPINE1, PDE3B, ENPP2, PF4, PRKCZ, MAPK8, EIF2AK2, PTGER4, PTGIS, PTPN6, PTPRM, RAG1, RB1, RREB1, SERPINB3, CCL24, SDCBP, SFRP5, SOD1, SOS1, SOS2, SP100, SPARC, SRY, STAT6, TAL1, KLF10, TNFSF4, TYROBP, UNG, VEGFB, WHSC1, ZIC2, ZNF16, FGF23, HIST1H4I, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, OGT, AP3B1, SERPINB7, RIPK1, TNFSF9, RIPK2, INPP4B, AP3D1, TNFSF18, RGN, ITGB1BP1, GPR55, IL27RA, SOX13, CTR9, PDCD6, RNF41, TRIB1, LRRC17, RAMP2, FSTL3, IKZF1, RAPGEF3, MAD2L2, DEAF1, CXCL13, GAS2L1, TOB2, SPINK5, STRAP |
1453 | GO:0002312 | 0.03 | 2.24 | 10.47 | 16 | 28 | B cell activation involved in immune response | ABL1, BCL3, CD28, GPR183, ERCC1, PTK2B, IFNG, IL10, CD180, STAT6, TNFSF4, UNG, WHSC1, RNF8, EXO1, IL27RA |
1454 | GO:0006195 | 0.03 | 2.24 | 10.47 | 16 | 28 | purine nucleotide catabolic process | CAT, GPX1, HPRT1, OGG1, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, PDE5A, RAPGEF3, PDE10A |
1455 | GO:0034166 | 0.03 | 2.24 | 10.47 | 16 | 28 | toll-like receptor 10 signaling pathway | CHUK, CREB1, ATF2, DUSP4, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK8, RPS6KA1, SKP1, UBB, CUL1, IKBKG, RIPK2 |
1456 | GO:0043967 | 0.03 | 2.24 | 10.47 | 16 | 28 | histone H4 acetylation | ACTL6A, BRCA1, BRCA2, EP300, KAT2A, PER1, OGT, HAT1, RUVBL1, ATG5, ATG7, TRIM16, RUVBL2, BRD8, WDR5, KAT7 |
1457 | GO:0048546 | 0.03 | 2.24 | 10.47 | 16 | 28 | digestive tract morphogenesis | ACVR2B, BCL2, BMP4, EPHB3, FGFR3, GATA4, HIF1A, HLX, IHH, SMAD3, SFRP5, SOX10, SOX11, TP73, WNT11, TP63 |
1458 | GO:0050994 | 0.03 | 2.24 | 10.47 | 16 | 28 | regulation of lipid catabolic process | ACACB, ADRA2A, ADRB2, AKT2, APOA1, APOH, CNR1, GPLD1, IDH1, IL1B, INS, PDE3B, PRKAA1, PRKCD, PRKCE, TWIST1 |
1459 | GO:0090596 | 0.00 | 2.24 | 54.61 | 83 | 146 | sensory organ morphogenesis | JAG1, ALDH1A3, AQP5, ATOH1, ATP2B2, ATP6V1B1, BAX, BBS4, BCL2, BCR, PRDM1, BMP4, CNTF, COL5A2, COL11A1, CRYGB, DLX5, DLX6, EPHA2, EPHB2, EYA1, FBN1, EFEMP1, FGF3, FGFR3, FZD2, GFI1, GNAT1, GNAT2, GNGT1, HMGN1, HMX2, IHH, INSIG1, KDR, KRT13, NRL, NTRK2, OTX1, OTX2, PRRX1, PRKCI, PTN, PTPRM, RAC1, RARB, RPGR, RPE65, RPL38, RS1, SALL1, SIX1, SIX3, SOD1, SOX1, SOX2, SOX9, SOX11, SP1, STAT3, ZEB1, TULP1, TWIST1, CLRN1, WNT1, WNT2, WNT2B, YY1, ZIC1, PAX8, FZD5, FZD6, BCAR3, ITGA8, HESX1, NRP1, SLC9A3R1, SLC4A7, NR2E3, IRX5, IKZF1, SEC24B, GJB6 |
1460 | GO:0070371 | 0.01 | 2.23 | 16.36 | 25 | 44 | ERK1 and ERK2 cascade | AVP, CRYBA1, CTSH, DUSP1, EPHA2, EPHA7, EPHB1, ERBB2, FBLN1, RAPGEF1, IGF1, ITGAV, OXTR, PTGER4, PTPN1, PTPN6, PTPRR, SOX9, STYX, ITGB1BP1, KLF4, SLC9A3R1, RANBP9, SPRY1, TNIP1 |
1461 | GO:0045859 | 0.01 | 2.23 | 14.98 | 23 | 41 | regulation of protein kinase activity | APLP2, APP, CCNE1, CCNG1, CDC25A, CDC25C, CDC42, CDK4, CKS1B, CKS2, FGR, RAC2, RAP2B, TSC1, TSG101, TNFRSF4, UVRAG, IKBKAP, DIRAS3, CCNE2, SLC9A3R1, CDC37, AKAP13 |
1462 | GO:0050671 | 0.00 | 2.23 | 26.93 | 41 | 72 | positive regulation of lymphocyte proliferation | ANXA1, BCL2, CD3E, CD4, CD6, CD28, CD80, CD86, CD38, CD59, CD81, CDKN1A, CHRNB2, GPR183, EFNB1, HES1, IFNG, IGF1, IGF2, IGFBP2, IL1B, IL2RA, IL12B, IL13, IL15, IL18, CD46, PRKCQ, XCL1, SPN, STAT5B, TAC1, TNFSF4, TNFRSF4, VCAM1, TNFSF9, RIPK2, VAV3, TNFSF13B, HHLA2, CORO1A |
1463 | GO:0051674 | 0.00 | 2.22 | 270.78 | 401 | 724 | localization of cell | AAMP, ABL1, ABL2, ACVR1, ACVRL1, ADAM10, ADARB1, ADCY3, ADRA2A, JAG1, AGTR1, AGTR2, AKT2, ALOX12, ALOX15B, ANG, ANGPT1, ANGPT2, ANXA1, ANXA3, ANXA5, APOA1, APOH, ARHGAP4, ARHGDIB, ASCL1, ASTN1, RERE, ATOH1, ATP1A4, ATP1B3, AXL, BAX, BBS2, BBS4, BCL2, BCR, BMP4, BMPR2, DST, BSG, BST2, BTG1, TSPO, CCK, KRIT1, CD44, CD58, CD63, CD81, CD151, CDC42, CDK6, CGA, CCR5, COL1A1, COL3A1, CLDN7, CSF1R, VCAN, CSPG4, CTGF, CTNNA1, CTNNA2, CTSH, CX3CR1, CXADR, DAB2, DAPK3, DBH, DCC, DCN, ACE, DCX, DIAPH1, DNAH5, DNAH8, DPEP1, DPP4, DPYSL3, HBEGF, ECM1, S1PR1, LPAR1, EDN3, EDNRA, EFNA1, EFNB1, EGR3, EPHA2, EMP2, CTTN, EMX2, EPHA1, EPHA8, EPHB1, EPHB3, EPS8, ERG, ETS1, F2, F2R, F2RL1, F3, F7, F10, PTK2B, FAP, FBLN1, EFEMP1, FCER1G, FGF4, FGF7, FGFR4, FGR, FLT1, FLT4, FSHB, FUT8, FYN, GAS6, B4GALT1, GPLD1, GPM6A, GPR15, GPX1, GRB2, GRB7, CXCL1, CXCL3, HIST1H1T, HCK, HEXB, HGF, NRG1, HIF1A, NR4A1, ONECUT1, HRH1, HRG, HES1, HSPB1, ICAM1, IFNG, IGF1, IGF1R, IGFBP3, IGFBP5, IL1B, IL10, IL12B, ILK, ING2, INS, INSL3, ISL1, ITGA1, ITGA3, ITGA4, ITGA5, ITGA9, ITGAM, ITGAV, ITGAX, ITGB1, ITGB4, JUN, KDR, KIT, KRAS, KRT2, LAMA3, LAMA4, LAMA5, LDHC, TACSTD2, EPCAM, SMAD3, SMAD7, SMCP, KITLG, NRCAM, NRTN, NTF3, NTRK2, NTRK3, OGDH, OLR1, P2RY1, P2RY2, P2RY6, SERPINE1, PAWR, PAX3, PCM1, PDE4B, PDE4D, ENPP2, SERPINF1, PEX7, PEX13, PF4, PF4V1, PFN1, PFN2, PIK3C2B, PIK3CB, PRCP, PRKCD, PRKCE, PRKCI, PRKD1, PRKCQ, PRKCZ, PRKX, PROC, RELN, PSEN1, PSG2, PTAFR, PTEN, PTGER4, PTK2, PTN, PTPN6, PTPRJ, PTPRM, PTPRR, RAB1A, RAB13, RAC1, RAC2, RAF1, RAP2A, RAP2B, RDX, RFX3, RPS6KB1, RPS19, RREB1, S100A2, S100A7, S100A8, S100A9, S100A12, SAA4, SERPINB3, SCNN1B, CCL20, CCL21, CCL22, CCL24, CCL25, CXCL6, CXCL5, XCL1, CX3CL1, SDC2, SDC4, SDCBP, SELE, SELL, SELP, SELPLG, SEMA3F, SEMG1, SFTPD, SGK1, SHC1, SIX1, SIX3, SLC9A1, SLC16A1, SNAI1, FSCN1, SORD, SOS1, SOX1, SOX9, SOX10, SP100, SPARC, SPN, SPOCK1, SRF, SRMS, STAT3, STAT5B, STC1, CDKL5, STK10, XCL2, TAC1, ADAM17, CNTN2, NR2F1, NR2F2, TMF1, TNP2, TNR, TOP2B, TRIP6, TWIST1, TYRO3, CLRN1, VAV1, VCAM1, VEGFB, VEGFC, VIL1, VTN, WNT11, SCG2, SEMA3B, ARHGEF5, SLC7A5, MADCAM1, USP9X, USP9Y, EPX, SOX14, RECK, CUL3, FOXN1, SORBS2, IKBKAP, DGKZ, DNAH17, UNC5C, DCHS1, CHRD, NUMB, TNFSF14, ADAM15, ADAM9, RAB11A, TNFRSF18, NRP2, NRP1, ARHGEF7, PHOX2B, TNFSF18, SEMA5A, DOK2, RGN, ITGB1BP1, KLF4, TAOK2, CER1, SLIT2, SLC9A3R1, ONECUT2, BAG4, CXCL14, BCAR1, CDC42BPB, SDC3, RAPGEF2, SEMA3E, SLK, HDAC4, ZEB2, ELMO1, GAB2, KIAA0319, HDAC6, PDCD6, GPC6, ARPC5, TSPAN1, ABI2, WASF2, TNK2, RNF41, TRIB1, APC2, CITED2, SEMA3A, ATP8A1, RAPGEF3, VAV3, CAP1, CREB3, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, PROCR, CXCL13, PDPN, NRG3, CHL1, GIPC1, IL24, VAX1, ABHD2, SLC7A9, BVES, CORO1A, STRAP |
1464 | GO:0097659 | 0.00 | 2.22 | 30.59 | 47 | 85 | nucleic acid-templated transcription | ANG, COX4I1, COX5B, COX6A1, COX6B1, COX7C, COX8A, CSTF3, CTGF, GLS, SFN, GPX2, GTF3C1, GTF3C2, DRG1, PRDX1, PPP5C, PRKAG1, PTMA, RGS12, RHEB, SRSF1, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SNRPE, SNRPF, TROVE2, TSC1, U2AF1, YWHAZ, SRSF9, RNGTT, COX7A2L, DDX21, GTF3C5, GTF3C4, GTF3C3, RBM8A, IVNS1ABP, RRAGA, PAPOLA, RNPS1, ADRM1, HSF2BP |
1465 | GO:0051271 | 0.00 | 2.22 | 50.12 | 76 | 134 | negative regulation of cellular component movement | ACTN1, ACVRL1, ADARB1, AGTR2, ALOX15B, ANGPT2, APOH, ARHGAP4, ARHGDIB, BCL2, BCR, BST2, KRIT1, CD63, COL3A1, CTNNA1, CX3CR1, DCN, DPEP1, DPYSL3, EPHA1, FBLN1, NRG1, HRG, IGFBP3, IGFBP5, ILK, TACSTD2, SMAD7, SERPINE1, SERPINF1, PFN2, PTEN, PTGER4, PTN, PTPRJ, PTPRM, PTPRR, RAP2A, RAP2B, CCL21, CCL25, SEMA3F, SEMG1, SP100, SRF, STAT3, STC1, NR2F2, WNT11, SEMA3B, RECK, CHRD, ADAM15, NRP1, SEMA5A, RGN, ITGB1BP1, KLF4, SLIT2, SLC9A3R1, SEMA3E, RNF41, TRIB1, CITED2, SEMA3A, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, CXCL13, NRG3, IL24, ABHD2, STRAP |
1466 | GO:0051347 | 0.00 | 2.22 | 154.09 | 231 | 412 | positive regulation of transferase activity | ABL1, ACVR2B, ADCY3, ADCY5, ADCY6, ADCY9, ADRA2A, ADRB2, ALK, ANG, ANGPT1, ARAF, BAD, BAX, CCND1, BMI1, BMP4, CALM1, CALM3, CAMK2A, CCNB1, CCNC, CCND3, CCNH, CCNT1, CCNT2, CD4, CD81, CDC20, CDC27, CDC42, CDKN1A, CENPE, CLU, CRKL, CSF1R, CSF2RB, CSPG4, ACE, GADD45A, DKC1, HBEGF, DUSP5, LPAR1, EDN3, EEF1A2, EFNA1, EFNA5, EMP2, EPHA8, ERBB2, EREG, ERCC6, ERN1, F2R, ACSL1, PTK2B, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FGR, FLT1, FLT3, FPR1, FYN, GAS6, GCG, GNG3, GRB2, RAPGEF1, GRIN2A, GRM1, HGF, NRG1, HSP90AB1, IGF2, IL1B, IL2RA, IL12B, ILK, INS, IRAK1, IRAK2, ITGA1, KIT, KRAS, LTF, MARK3, MAP3K5, KITLG, MAP3K11, NTF3, NTRK1, NTRK3, NVL, P2RX7, PEBP1, PDE6G, PDE6H, PFKFB1, PFKFB2, PIK3CB, PIM1, PPP5C, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCQ, PRKCZ, EIF2AK2, RELN, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, PTPN1, PTPRA, RAC1, RAF1, RASA2, RPS3, S100A12, CCL21, SDC4, SHC1, STIL, SKP1, SLC11A1, SNCA, SOD1, SOS1, STK10, STK11, ADAM17, TP73, TPD52L1, TRAF2, UBB, UBE2L3, UCN, WNT11, ZNF16, FZD5, ARHGEF5, FGF23, FZD4, FZD8, CUL3, CUL1, IKBKG, CAMK1, MAPKAPK5, CDC14B, PDE5A, PEA15, CDC23, RIPK1, ADAM9, RIPK2, TNFRSF10B, TNFRSF10A, CDC16, UNC119, AURKB, VAPB, ITGB1BP1, S1PR2, KLF4, TAOK2, PSMF1, NRG2, TRAF4, RAPGEF2, SLK, ATG13, ZEB2, EPM2AIP1, PSMD6, OXSR1, TNFSF15, RBX1, ABI1, TOM1L1, RAD50, AKAP9, RASA4, PSME3, PSMD14, ANAPC10, VAV3, STK25, CCT4, CCT2, NRG3, FRS3, MALT1, JTB, COPS8, UBE2C, MAP4K5, FZD10 |
1467 | GO:0021987 | 0.00 | 2.22 | 19.07 | 29 | 51 | cerebral cortex development | ASCL1, ATOH1, BAD, BAX, BBS2, BBS4, COL3A1, CX3CR1, DCX, EMX1, EMX2, HIF1A, NTRK2, PEX13, RELN, PSEN1, PTPRS, RAC1, SOX2, SRD5A1, TACC1, NR2F1, TSC1, NRP1, SLIT2, SEMA3A, TACC3, ATG7, TACC2 |
1468 | GO:0001890 | 0.00 | 2.22 | 30.29 | 46 | 81 | placenta development | ADM, ANG, BIRC2, ARNT, ASCL2, PRDM1, BMPR2, BSG, CCNF, CDX2, CDX4, CTSV, DCN, ESR1, GHSR, GJB5, GRB2, HIF1A, HES1, HSP90AB1, RBPJ, IL10, ITGA4, KRT19, LLGL2, CITED1, SERPINE1, PTGIS, PTK2, RXRA, SNAI1, SOD1, SP1, SPINT1, ST14, STC1, NR2F2, VCAM1, WNT2, FZD5, FOSL1, SOCS3, HAND1, CUL7, PRDX3, TMED2 |
1469 | GO:0046395 | 0.00 | 2.22 | 30.92 | 47 | 83 | carboxylic acid catabolic process | AHCY, ALDH9A1, AMT, ARG1, ASL, AUH, BCAT1, BCKDHA, CBS, CCBL1, CDO1, CRYM, CTH, DBT, GAD1, GAD2, GLDC, GLS, GLUD1, GLUL, GOT1, GPT, GSTZ1, HSD17B10, HAL, HMGCL, HNMT, IDO1, ALDH6A1, OAT, OGDH, OTC, PAH, QDPR, RENBP, SHMT1, SUOX, TAT, TST, BBOX1, DDO, KYNU, AASS, BCKDK, ALDH1L1, SDS, HIBADH |
1470 | GO:0040008 | 0.00 | 2.22 | 32.80 | 50 | 89 | regulation of growth | ACACB, ACTL6A, APP, BBS4, C3, CCNB1, CD81, CREB1, DIO3, DRD3, E4F1, GAMT, GAS6, GATA4, GATA6, GHRH, GHRHR, GHSR, HLX, IGF2, RBPJ, IHH, ING2, PPIB, PTGER4, RAG2, RPS6KB1, SHC1, SIX1, SOD1, STAT3, STAT5B, VIL1, WFS1, WNT2, HMGA2, ATRN, RUVBL1, HDAC3, SOCS3, LATS1, SOCS6, BCL2L11, IKZF1, UBE2E3, ENOX2, CARM1, RUVBL2, BRD8, AFG3L2 |
1471 | GO:0032388 | 0.01 | 2.21 | 17.06 | 26 | 46 | positive regulation of intracellular transport | AKT2, BAD, BCL2, BID, CDC42, CHRM1, DNM1, STOM, ERBB2, FCER1G, FGR, OAZ1, OAZ2, PCM1, MAPK8, YWHAZ, DYNLL1, VAMP8, SYNJ1, ITGB1BP1, GAB2, C2CD5, BCL2L11, SIVA1, YWHAQ, CAPN10 |
1472 | GO:0032984 | 0.00 | 2.21 | 56.85 | 86 | 152 | macromolecular complex disassembly | ADD1, BNIP3, CAPG, CAPZA1, CAPZB, CCNB1, CFL2, EIF5A, EPS8, ETF1, F2RL1, FAU, NRG1, HMGA1, HSPA8, KLC1, RPL10A, CHMP1A, PEX14, RDX, UPF1, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, SET, SGK1, SLN, SMARCA4, SMARCC2, SMARCD1, SMARCD3, SMARCE1, SPAST, AURKA, TMOD1, VIL1, DENR, SYNJ1, SEMA5A, RPL14, ARHGEF2, AURKB, RPL23, IST1, DNAJC6, HDAC6, APC2, KATNB1, GAS2L1, AVIL, KIF2C, STMN2, SUPT16H, RPL35 |
1473 | GO:0043534 | 0.01 | 2.21 | 16.46 | 25 | 44 | blood vessel endothelial cell migration | ACVRL1, AGTR2, ANGPT1, ANGPT2, APOA1, EFNA1, EGR3, EPHA2, EMP2, PTK2B, GPLD1, GPX1, NR4A1, HRG, HSPB1, ITGB1, KDR, PRCP, PRKD1, SRF, VEGFC, NRP1, ITGB1BP1, KLF4, SLIT2 |
1474 | GO:0040013 | 0.00 | 2.21 | 54.23 | 82 | 145 | negative regulation of locomotion | ACVRL1, ADARB1, AGTR2, ALOX15B, ANGPT2, APCS, APOH, ARHGAP4, ARHGDIB, BCL2, BCR, BST2, KRIT1, CD63, COL3A1, CTNNA1, CX3CR1, DCN, DPEP1, DPYSL3, EPHA1, FBLN1, NRG1, HRG, IFNA2, IGFBP3, IGFBP5, ILK, ITGAV, TACSTD2, SMAD7, SERPINE1, SERPINF1, PFN2, PTEN, PTGER4, PTN, PTPRJ, PTPRM, PTPRR, RAP2A, RAP2B, CCL21, CCL25, SEMA3F, SEMG1, ST6GAL1, SP100, SRF, STAT3, STC1, NR2F2, WNT11, TRIM25, SEMA3B, RECK, CHRD, ADAM15, NRP1, SEMA5A, RGN, ITGB1BP1, KLF4, SLIT2, SLC9A3R1, SEMA3E, RNF41, TRIB1, CITED2, SEMA3A, IFITM3, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, CXCL13, IFITM2, NRG3, IL24, ABHD2, STRAP |
1475 | GO:0051247 | 0.00 | 2.21 | 269.08 | 398 | 725 | positive regulation of protein metabolic process | ABL1, ABL2, ACVR1, ACVR2A, ACVR2B, ACVRL1, ADCY3, ADCY5, ADCY6, ADCY9, ADRA1B, ADRB2, AGTR1, AGTR2, AKT2, ALK, ALOX12, ANG, ANGPT1, APAF1, BIRC2, BIRC3, XIAP, APP, ARAF, ARNT, ATM, ATP6AP1, AVP, AVPR2, BAD, BAX, CCND1, BCL2, BCL3, BID, BMI1, BMP1, BMP3, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, BOK, BRCA1, C3, CALM1, CALM3, CAMK2A, CASP1, CASP9, CAV2, CCK, CCNC, CCND3, CCNH, CCNT1, CCNT2, CD3E, CD4, CD28, CD80, CD86, TNFRSF8, CD36, CD44, CDC42, CDK4, CDK9, CDKN1A, CDKN2A, CENPE, CIRBP, CNTF, COL4A3, CREBL2, CRH, CRKL, CSF1R, CSF2RB, CSPG4, CTF1, CTGF, CTSH, DAZ1, ACE, GADD45A, DNMT1, DNMT3B, HBEGF, DUSP5, DYRK1A, GPR183, LPAR1, EDN3, EDNRA, EEF2, EFNA1, EFNA5, EIF5A, ELAVL1, EMP2, EPHA7, EPHA8, ERBB2, EREG, ERCC6, ERN1, ESR1, F2, F2R, F2RL1, F3, ACSL1, FBLN1, FGA, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FGG, FLT1, FLT3, FLT3LG, FLT4, FPR1, FSHR, FYN, GAS6, GCG, KAT2A, GDF9, GFRA2, GNG3, GOLGA2, GRB2, RAPGEF1, GRIN2A, GRM1, HIST1H1B, HCLS1, HGF, NRG1, HIP1, UBE2K, HMGCR, HNRNPD, HPX, HES1, HSPB1, HSP90AB1, HTR2C, ICAM1, IFI16, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGF1, IGF1R, IGF2, IGFBP3, IL1A, IL2RA, IL12B, IL13, IL15, IL18, ILK, INHA, INS, IRAK1, IRAK2, IRF1, ISL1, ITGA1, ITGA5, ITGB1, JARID2, JUN, KDR, KISS1, KIT, KLKB1, KRAS, LTF, SMAD3, MARK3, MAP3K5, KITLG, MAP3K11, PPP1R12A, SLC11A2, NTF3, NTRK1, NTRK2, NTRK3, TNFRSF11B, P2RX1, P2RX7, P2RY1, PEBP1, PAWR, PCOLCE, PDE6G, PDE6H, ENPP2, PFN2, PIK3CB, PIM1, PPP5C, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCE, PRKD1, PRKCQ, PRKCZ, MAPK8, EIF2AK2, RELN, PSAP, PTAFR, PTGER4, PTPN1, PTPRA, RAB1A, RAC1, RAF1, RAP2A, RAP2B, RASA2, REST, RPS3, RPS4X, RPS6KB1, RPS6KB2, RXRA, RYK, S100A7, S100A8, S100A9, S100A12, SERPINB3, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SDCBP, SEMG1, SHC1, STIL, SLC11A1, SNCA, SOD1, SOS1, SOX2, SPN, SREBF1, STAT5B, STK10, STK11, XCL2, ADAM17, CNTN2, CLEC3B, TNFRSF1A, TP73, TPD52L1, TRAF2, TTK, TNFRSF4, UBE2L3, UBE3A, UCN, NR1H2, VEGFB, VEGFC, VTN, WFS1, WNT1, WNT11, FZD5, AIMP2, ARHGEF5, FGF23, CDK2AP1, PICALM, FZD4, FZD7, FZD8, BCAR3, OGT, IKBKG, CAMK1, MAPKAPK5, CDC14B, PDE5A, PEA15, TRADD, EED, RIPK1, CRADD, TNFSF10, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10B, TNFRSF10A, NRP1, CFLAR, HDAC3, KAT2B, EIF2B5, RPS6KA4, TNFSF18, UNC119, LATS1, AIFM1, ARHGEF2, VAPB, CRLF1, ITGB1BP1, GPR55, S1PR2, KLF4, TAOK2, EIF2AK3, AKAP6, GDF15, BAG4, NRG2, TRAF4, CTR9, RAPGEF2, SLK, HDAC4, EIF4A3, ATG13, IST1, RB1CC1, ZEB2, OXSR1, TNFSF15, RBX1, CASP8AP2, ABI1, PDCD6, BCL2L10, BCL2L11, TOM1L1, RAD50, AKAP9, RASA4, SORBS3, TNK2, CNPY2, ABCA7, KLF2, PRG3, PEMT, PIAS3, RAPGEF3, MAD2L2, STK25, SEMA4D, ARL6IP5, ARFGEF1, USP16, KHDRBS1, NRG3, FRS3, RUVBL2, ARID5A, MALT1, JTB, COPS8, IL24, ADRM1, GLMN, MAP4K5, CHEK2, FZD10 |
1476 | GO:0048812 | 0.00 | 2.20 | 133.33 | 200 | 359 | neuron projection morphogenesis | ACTB, ACTG1, ADAM10, ANGPT1, APP, ARAF, ATOH1, ADGRB1, BCL2, CACNB3, CACNB4, CALM1, CALM3, CAMK2A, CCK, CD72, CDC42, CHN1, AP2S1, CLU, CLTA, CNP, COL3A1, COL4A3, COL4A5, COL5A2, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2RB, CSNK2A1, CSNK2A2, DCC, DLG3, DLX5, DNM1, DPYSL3, EPYC, HBEGF, ECM2, DUSP5, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EPHA2, EPHA1, EPHA5, EPHA7, EPHA8, ERBB2, EREG, ETV4, EXT1, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, GDI1, GFRA1, GPM6A, GRB2, GRIN2A, ARHGAP35, HSPA8, HSP90AA1, HSP90AB1, IL2RA, ISL1, ITGA1, ITGA5, ITGA9, ITGAV, KIF5A, KIT, KRAS, ABLIM1, MARK3, KITLG, NRTN, NTF3, NTF4, NTRK1, NTRK2, NTN3, OGN, OMG, OTX2, PEBP1, PPP5C, PRKCQ, PSPN, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTK2, PTPRA, PTPRM, RAC2, RAF1, RASA2, RPL24, RPS6KA1, RYK, S100A6, S100B, SCN5A, SDCBP, SHC1, SIAH1, SOS1, SOS2, SPAST, STXBP1, CNTN2, TBCE, DYNLT1, TOP2B, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, WEE1, FGF23, RND2, CUL3, CNTNAP1, GAS7, UNC5C, NUMB, PEA15, ARHGEF7, PHOX2B, RPS6KA4, KALRN, ARHGEF1, NRXN3, NRXN1, PSMF1, NRG2, FEZ2, IST1, ARHGEF11, FARP2, PSMD6, RBX1, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, PSME3, PSMD14, SPON2, VAV3, CAP1, STK25, ATG7, ARPC1A, DPYSL4, TBR1, CHL1, FRS3, RAB10, AFG3L2, VAX1 |
1477 | GO:0035051 | 0.00 | 2.20 | 22.44 | 34 | 60 | cardiocyte differentiation | ACVR1, JAG1, AGTR2, BMP4, CAV3, CCNB1, CXADR, GATA4, GATA6, KAT2A, NRG1, HES1, RBPJ, ISL1, ITGB1, RARA, RARB, REST, RXRA, SGCB, SLC9A1, SRF, TSC1, TWIST1, CSRP3, SORBS2, HDAC3, CTDP1, AKAP6, ATG5, MAML1, SPEG, ATG7, BVES |
1478 | GO:0071804 | 0.00 | 2.20 | 43.01 | 65 | 115 | cellular potassium ion transport | ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP1A4, ATP1B3, FXYD2, ATP4A, HCN2, CASQ2, CAV3, CNGA1, DNM2, DPP6, EDN3, HTR3A, KCNA1, KCNA2, KCNA3, KCNA4, KCNA10, KCNC1, KCNC2, KCND2, KCND3, KCNE1, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ12, KCNJ13, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN1, KCNN4, KCNQ1, KCNS2, KCNS3, REST, ABCC8, SUMO1, KCNAB1, KCNK5, KCNAB3, KCNK6, AKAP7, AKAP6, OXSR1, SLC12A6, KCNE2, KCNE3, HCN4, ABCC9, AKAP9, KCNMB2, RAPGEF3, WWP2 |
1479 | GO:0002703 | 0.00 | 2.20 | 28.42 | 43 | 76 | regulation of leukocyte mediated immunity | BCR, BST2, BTK, C3, CD28, CLC, F2RL1, FCER1G, FCER2, FGR, HPX, ICAM1, IFNA2, IFNG, IGF2, IL1B, IL10, IL12B, IL13, IL13RA2, P2RX7, SERPINB9, PRKCZ, PTAFR, PTPN6, PVR, RAC2, SERPINB4, XCL1, SPN, STAT5B, STAT6, STXBP2, TRAF2, TNFSF4, UNG, VAV1, WHSC1, FZD5, VAMP8, IL27RA, GAB2, MALT1 |
1480 | GO:0070665 | 0.00 | 2.20 | 28.42 | 43 | 76 | positive regulation of leukocyte proliferation | ANXA1, BCL2, CD3E, CD4, CD6, CD28, CD80, CD86, CD38, CD59, CD81, CDKN1A, CHRNB2, GPR183, EFNB1, HES1, IFNG, IGF1, IGF2, IGFBP2, IL1B, IL2RA, IL12B, IL13, IL15, IL18, CD46, KITLG, PRKCQ, XCL1, ST6GAL1, SPN, STAT5B, TAC1, TNFSF4, TNFRSF4, VCAM1, TNFSF9, RIPK2, VAV3, TNFSF13B, HHLA2, CORO1A |
1481 | GO:1902107 | 0.00 | 2.20 | 28.42 | 43 | 76 | positive regulation of leukocyte differentiation | ANXA1, ATP6AP1, AXL, BAD, PRDM1, BTK, CA2, CD80, CD86, CREB1, CSF1R, EGR3, FLT3LG, GAS6, GNAS, HCLS1, HLX, IFNG, IHH, IL1B, IL2RA, IL12B, IL15, IL17A, JUN, CD46, KITLG, PF4, PRKCZ, RAG1, RARA, RB1, STAT5B, KLF10, TNFSF4, OGT, AP3B1, RIPK1, TNFSF9, RIPK2, AP3D1, TRIB1, IKZF1 |
1482 | GO:0043507 | 0.02 | 2.19 | 11.22 | 17 | 30 | positive regulation of JUN kinase activity | ERCC6, ERN1, PTK2B, IL1B, MAP3K5, MAP3K11, PTPN1, RPS3, TRAF2, FZD5, ARHGEF5, FZD4, FZD8, RIPK1, ZEB2, MAP4K5, FZD10 |
1483 | GO:0000079 | 0.00 | 2.19 | 19.82 | 30 | 53 | regulation of cyclin-dependent protein serine/threonine kinase activity | CCND1, CCNC, CCND3, CCNG1, CCNH, CCNT1, CCNT2, CDC25A, CDC25C, CDKN1A, CDKN2A, CKS1B, CKS2, GADD45A, SFN, HHEX, PIM1, PTEN, STIL, ADAM17, NR2F2, TNFAIP3, CUL3, KAT2B, DIRAS3, LATS1, CCNE2, HEXIM1, UBE2C, CDC37 |
1484 | GO:2001235 | 0.00 | 2.19 | 23.12 | 35 | 62 | positive regulation of apoptotic signaling pathway | AGTR2, APAF1, BNIP3, CTNNA1, CTSH, CYLD, DAPK3, SFN, SMAD3, MAL, PPP2R1A, PPP2R1B, PPP3R1, PRKCD, MAPK8, PTEN, TPD52L1, TRAF2, YWHAZ, SRPX, TP63, DYNLL1, PEA15, TRADD, RIPK1, CRADD, HRK, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR, PDCD7, SIVA1, RBCK1, YWHAQ |
1485 | GO:0007612 | 0.01 | 2.19 | 14.51 | 22 | 39 | learning | AMPH, BCHE, COMT, CTNND2, FYN, JUN, NTRK2, NTSR1, PARK2, PRKAR2B, PTGS1, PTN, SLC8A3, CNTN2, EPM2A, FOSL1, AAAS, DGKI, NRXN3, NRXN1, NRXN2, ATP8A1 |
1486 | GO:0043903 | 0.00 | 2.19 | 41.11 | 62 | 110 | regulation of symbiosis, encompassing mutualism through parasitism | ADAR, ADARB1, APCS, BAD, BCL2, BST2, CAV2, CCNH, CCNT1, CD28, CDK9, CHD1, DDX5, EP300, STOM, ERCC3, F2RL1, FBLN1, NR5A2, GTF2F1, IFI16, IFIT1, IFNA2, ILF3, ISG20, ITGAV, JUN, LTF, OAS3, PARK2, PPIB, PPID, EIF2AK2, REST, SLPI, SMARCA4, SP1, SP100, SRPK2, TRIM21, SSRP1, STAT1, STAU1, SUPT4H1, DYNLT1, TMPRSS2, TOP2A, TSG101, TRIM25, RAB7A, HMGA2, CTDP1, VAPB, BCL2L11, TRIM13, TNIP1, IFITM3, PPIE, PPIH, TRIM38, IFITM2, SUPT16H |
1487 | GO:0030900 | 0.01 | 2.19 | 15.16 | 23 | 41 | forebrain development | APAF1, APLP2, APP, ATRX, CNP, FABP7, FGFR3, FYN, ARHGAP35, HHEX, KRAS, PCDH9, PCM1, RRM1, STIL, SSTR2, NR2F2, TOP2B, WNT2B, OGT, CHRD, HESX1, IKZF1 |
1488 | GO:1903305 | 0.05 | 2.19 | 8.59 | 13 | 23 | regulation of regulated secretory pathway | BCR, F2RL1, FCER1G, FGR, IL13, IL13RA2, PTAFR, RAB27A, RAC2, STXBP2, VAMP8, RAB3D, GAB2 |
1489 | GO:0031331 | 0.00 | 2.19 | 60.44 | 91 | 162 | positive regulation of cellular catabolic process | ADRA1B, ADRA2A, AKT2, APOA1, APOH, ARNT, BAX, ZFP36L2, CAV3, CCNB1, CD81, CDC20, CDC27, CLU, CSNK1D, DAB2, PTK2B, GPD1, GPLD1, DNAJB2, IGF1, IL1B, INS, SMAD7, P2RX7, PARK2, PRKCD, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, PTPN1, RB1, RDX, UPF1, SGTA, SKP1, SUMO3, SNCA, AURKA, SUPV3L1, TNFAIP3, TNFRSF1B, TWIST1, UBB, SUMO1, ZFP36, USP5, CUL3, CUL1, CDC23, ADAM9, CDC16, RGN, CNOT8, PSMF1, GTPBP1, RNF14, DLGAP5, RNF40, KEAP1, PSMD6, KCNE2, PSME3, PSMD14, TRIB1, ANAPC10, RAPGEF3, ARIH2, UBE2C |
1490 | GO:0002437 | 0.05 | 2.18 | 8.60 | 13 | 23 | inflammatory response to antigenic stimulus | AHCY, BDKRB2, C3, CD6, CD28, CNR1, FCER1G, ICAM1, RBPJ, IL1A, IL1B, IL1RN, IL2RA |
1491 | GO:1901361 | 0.00 | 2.18 | 18.47 | 28 | 50 | organic cyclic compound catabolic process | AMBP, AOX1, STS, BLVRA, BLVRB, CCBL1, COMT, CYP2A6, CYP3A4, CYP24A1, DBH, DIO3, GOT2, GSTZ1, HAL, HNMT, IDO1, ALDH6A1, PAH, QDPR, TAT, UGT2B4, FGF23, HSD17B6, ALDH4A1, KYNU, SNX17, ALDH1L1 |
1492 | GO:0000077 | 0.00 | 2.18 | 35.16 | 53 | 94 | DNA damage checkpoint | ATM, ATR, CCND1, BRCA1, CDC5L, CDK2, CDKN1A, CHEK1, ATF2, CRY1, FOXO4, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, RAD1, RPA2, TP73, UBB, XPC, HMGA2, CUL4A, DGKZ, CDC14B, TP63, PEA15, CRADD, TAOK2, PSMF1, CLOCK, PSMD6, FEM1B, PSME3, PSMD14, CHEK2 |
1493 | GO:0045637 | 0.00 | 2.18 | 20.52 | 31 | 55 | regulation of myeloid cell differentiation | APCS, BGLAP, C1QC, CAMK4, CDK6, PTK2B, FSHB, FSHR, GABPA, INHA, LTF, RARA, STAT5B, TYROBP, HIST1H4I, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, INPP4B, GPR55, CTR9, RNF41, LRRC17, FSTL3, GAS2L1, TOB2 |
1494 | GO:0071310 | 0.00 | 2.18 | 52.37 | 81 | 155 | cellular response to organic substance | AARS, ABL2, ACADVL, ADD1, ALOX12, ASNA1, ATF4, BAX, CCND1, BCL2, PRDM1, TSPO, CASP1, CD6, CD9, CD36, CD81, CEBPE, TPP1, CTH, BRINP1, DDIT3, LPAR1, PHC1, EFNA5, EGR2, EIF2S1, EPHA5, EXTL3, FCER1G, GPR27, HDGF, HMGCR, FOXA2, KRT13, LTF, CD180, DNAJB9, ATXN3, OXCT1, EIF2AK2, PSAP, PTPRN2, SDF2, SLC2A5, SMARCD1, SRF, SSR1, SULT1A3, ABCC8, SYP, WFS1, WNT11, ZNF16, ZNF35, ZBTB17, FZD7, ALDH1A2, VAPB, HMGN3, NRXN1, EIF2AK3, LITAF, GOSR2, TATDN2, CUL7, C2CD2L, PREB, PDIA6, CALCRL, TRIB1, SPON2, CREB3, CERS1, GJB6, SEC61B, PDIA5, COPS5, KDELR3, FZD10, SEC63 |
1495 | GO:0001659 | 0.05 | 2.18 | 8.60 | 13 | 23 | temperature homeostasis | ABAT, ACADL, ACADVL, ADRB2, CNR1, DBH, GPX1, IL1A, IL1B, IL1RN, NTSR1, STAT3, TRPV1 |
1496 | GO:0002709 | 0.05 | 2.18 | 8.60 | 13 | 23 | regulation of T cell mediated immunity | CLC, IFNA2, IL1B, IL12B, P2RX7, PRKCZ, PVR, XCL1, SPN, TRAF2, TNFSF4, FZD5, MALT1 |
1497 | GO:0006509 | 0.05 | 2.18 | 8.60 | 13 | 23 | membrane protein ectodomain proteolysis | ADAM10, ADRA2A, GPLD1, IFNG, IL1B, IL10, P2RX7, PRKCQ, PSEN1, ADAM17, TNFRSF1B, ADAM19, ADAM9 |
1498 | GO:0006949 | 0.05 | 2.18 | 8.60 | 13 | 23 | syncytium formation | CAV3, CD53, ERCC1, FLT3LG, STAT1, WNT1, CAMK1, TNFSF14, ADAM9, CFLAR, DYRK1B, GDF15, RAPGEF3 |
1499 | GO:0031424 | 0.05 | 2.18 | 8.60 | 13 | 23 | keratinization | CDC42, CDH3, EVPL, SFN, KRT2, PPL, SPRR1B, SPRR2A, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3 |
1500 | GO:0032613 | 0.05 | 2.18 | 8.60 | 13 | 23 | interleukin-10 production | BCL3, F2RL1, FCER1G, IL12B, IDO1, CD46, PRG2, PRKCD, PRKCZ, PTGER4, XCL1, TNFSF4, EPX |
1501 | GO:0042461 | 0.05 | 2.18 | 8.60 | 13 | 23 | photoreceptor cell development | BBS4, PRDM1, GNAT1, GNAT2, GNGT1, NRL, NTRK2, PRKCI, RPGR, RPE65, TULP1, IFT140, NR2E3 |
1502 | GO:0090278 | 0.05 | 2.18 | 8.60 | 13 | 23 | negative regulation of peptide hormone secretion | ADRA2A, ANXA5, CRH, CRHBP, GHSR, HMGCR, KCNJ11, PARK2, PDE4C, REST, SREBF1, ABCC8, STXBP5L |
1503 | GO:0072171 | 0.01 | 2.17 | 14.59 | 22 | 39 | mesonephric tubule morphogenesis | AGTR2, BCL2, BMP4, CD44, EYA1, GPC3, HOXD11, HES1, ILK, LAMA5, TACSTD2, CITED1, PBX1, PSPN, SALL1, SIX1, SOX9, WNT1, WNT11, WNT2B, PAX8, DCHS1 |
1504 | GO:0015850 | 0.00 | 2.17 | 39.21 | 59 | 105 | organic hydroxy compound transport | ABAT, ABCA1, ABCA2, ACACB, ADRA2A, AGTR1, AGTR2, APOA1, AQP5, AQP6, AQP7, BMP6, TSPO, CD36, CFTR, CHRNB2, CLU, CNR1, CPT1B, CPT2, CRH, DRD3, FCER1G, GALR1, FFAR3, KCNA2, LCAT, LIPC, OSBP, OXTR, P2RX1, P2RY1, PARK2, PCP4, PSEN1, PTGS1, RAB3B, SEC14L1, SLC5A3, SLC16A1, SLC18A1, SLC22A1, SLC22A3, SLC22A2, SLC22A5, SNCA, STAR, TAC1, TMF1, NR1H2, SOAT2, CADPS, SLC16A6, SLC16A5, SLC16A4, SLC16A7, LIPG, ABCG1, ABCA7 |
1505 | GO:0051668 | 0.00 | 2.17 | 20.57 | 31 | 55 | localization within membrane | ARCN1, AREG, ARF1, CD59, COPA, CSNK1D, CTSZ, GOLGA2, GRIA1, INSIG1, LMAN1, MAL, PPP6C, PRKCI, RAB1A, RAC1, RALA, TRAPPC2, TRAPPC10, CUL3, USO1, VAPB, COPB2, SEC22B, GOSR2, PREB, ATP8A1, SEC24B, SEC23A, SEC24A, TMED2 |
1506 | GO:0010631 | 0.01 | 2.17 | 15.22 | 23 | 41 | epithelial cell migration | APOA1, DPP4, EFNA1, EGR3, EPHA2, EMP2, FAP, FGF4, GPX1, NR4A1, ITGB1, KIT, KRT2, PRCP, PRKX, PTEN, PTK2, RAB13, S100A2, SRF, SCG2, ZEB2, GIPC1 |
1507 | GO:0002694 | 0.00 | 2.17 | 78.82 | 118 | 211 | regulation of leukocyte activation | ANXA1, ATM, AXL, BAD, BCL2, BCR, PRDM1, BMP4, BPI, BTK, CAMK4, CBLB, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD28, CD80, CD86, CD37, CD38, CD59, CD81, CDC42, CDKN1A, CDKN2A, CHRNB2, CLC, CTLA4, CYLD, DPP4, GPR183, EFNB1, EGR3, ERBB2, F2RL1, FLOT2, FLT3, FLT3LG, FYN, GAS6, GRB2, HLA-DQA1, HLX, HES1, IFNA2, IFNG, IGF1, IGF2, IGFBP2, IHH, IL1B, IL2RA, IL10, IL12B, IL15, IL18, IDO1, INHA, IRF1, LMO1, CD46, PAWR, PRKAR1A, PRKCQ, PRKCZ, PTAFR, PTPN6, RAC1, RAG1, RARA, CCL21, XCL1, SFTPD, SNCA, SOD1, SOS1, SOS2, SOX11, SPN, STAT5B, STAT6, TAC1, ZEB1, TNFAIP3, TRAF2, TNFSF4, TNFRSF4, TYRO3, SCGB1A1, UNG, VAV1, VCAM1, WHSC1, FOXN1, AP3B1, PDE5A, TNFSF14, TNFSF9, RIPK2, AP3D1, TNFSF18, IL1RL1, SOCS6, GRAP2, IL27RA, SOX13, RNF41, IKZF1, VAV3, TNFSF13B, MALT1, SPINK5, GLMN, HHLA2, CORO1A |
1508 | GO:0099536 | 0.00 | 2.17 | 152.22 | 226 | 407 | synaptic signaling | ABAT, ACHE, ADCY3, ADCY5, ADCY6, ADCY9, ADRB2, ALDH2, AMPH, ARF1, ATP1A2, ATP2B2, BCHE, HCN2, TSPO, CA2, CACNA1A, CACNA1B, CACNB3, CACNB4, CALM1, CALM3, CAMK4, CAMK2A, CD38, CDC20, CDH8, CHAT, CHRM1, CHRM3, CHRNB2, CHRNB4, AP2S1, CLCN3, CNP, CNR1, CNR2, COMT, CORT, CREB1, CRH, CRHBP, CTNND2, CX3CR1, DBH, DBI, DLG2, DLG3, DNM1, DRD3, DRD5, DTNA, EGR2, EGR3, ETV5, PTK2B, GABRA4, GABRA5, GABRA6, GABRG1, GABRR1, GABRR2, GAD1, GAD2, GFAP, GLRA1, GLRA2, GLS, GLUL, GNAI1, GNAL, GNB1, GNG3, GNG10, GNGT1, GNGT2, GPR1, GRIA1, GRIA4, GRID2, GRIK3, GRIN2A, GRM1, HRH1, HRH2, HSPA8, HTR2C, HTR3A, IFNG, KCNA1, KCNA2, KCNA3, KCNA4, KCNA10, KCNC1, KCNC2, KCND2, KCND3, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ12, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN1, KCNN4, KCNQ1, KCNS2, KCNS3, KIF5A, KISS1, KIT, KRAS, ATXN3, NTF3, NTRK1, NTRK2, NTSR1, OMP, OXTR, P2RX1, P2RX3, P2RX4, P2RX7, P2RY11, PARK2, PCDH8, PDYN, PFN2, SEPT5, PRKACB, PRKCE, PRKCZ, RELN, PSEN1, PTEN, PTGER4, PTN, PTPRN2, RAB3B, RAB5A, RAC1, RAC3, RAF1, RARA, RPS6KA1, S100B, CX3CL1, SDCBP, SLC1A3, SLC1A6, SLC1A7, SLC6A11, SLC6A12, SLC6A13, SLC8A3, SLC18A1, SLC22A2, SNAP25, SNCB, SNCA, SRF, STAR, STAU1, STXBP1, ABCC8, SYN1, SYP, SYPL1, SYT1, SYT4, SYT5, TAC1, CNTN2, TNR, UCN, VIPR1, KCNAB1, SYN3, DOC2A, CADPS, STX11, RAB11A, LIN7A, SYNJ1, BSN, BAIAP3, UNC119, USP14, SLC6A5, DGKI, KCNAB3, S1PR2, SNAP29, NRXN3, NRXN1, NRXN2, KCNK6, PICK1, APBA3, GABBR2, RIN1, SNCAIP, RAPGEF2, RIMS2, SNPH, EIF4A3, SNAP91, SLC12A6, HCN4, ABCC9, AKAP9, KCNMB2, CACNG2, BAIAP2, GIPC1, CPLX2, CPLX1 |
1509 | GO:0044248 | 0.00 | 2.17 | 54.17 | 82 | 150 | cellular catabolic process | ABAT, ABL1, ABL2, ACHE, ACTL6A, ADH5, ALDH9A1, AMT, ARG1, ASL, ATP6V0A1, AUH, BCAT1, BCKDHA, BNIP2, CAPN1, CASP1, CBS, CDO1, TPP1, CRYM, VCAN, CSPG4, CTH, CYP24A1, DAPK3, DBT, ACE, EEF1A2, CTTN, ESD, GAD1, GAD2, GALNS, KAT2A, GFAP, GLB1, GLDC, GLS, GLUD1, GLUL, GOT1, GOT2, GPT, HSD17B10, HEXA, HMGCL, IDS, IDUA, IFI16, LTA4H, LUM, OAT, OMD, OGDH, OGN, OTC, OXCT1, RENBP, RNPEP, SHMT1, SREBF1, SUOX, U2AF1, ZBTB17, FZD5, FGF23, BBOX1, DDO, RUVBL1, ALDH4A1, RAB33A, GPRASP1, RB1CC1, XYLB, AASS, BCKDK, AKR1A1, SDS, KERA, ADAMTS13, HIBADH |
1510 | GO:0031532 | 0.02 | 2.16 | 11.95 | 18 | 32 | actin cytoskeleton reorganization | ANXA1, CXADR, S1PR1, CTTN, EPS8, FGF7, INSRR, KIT, PRKCZ, PTPN1, RALA, RAP2A, S100A9, SHC1, S1PR2, CDC42BPB, FARP2, CAPN10 |
1511 | GO:1901564 | 0.00 | 2.16 | 30.80 | 47 | 87 | organonitrogen compound metabolic process | ACY1, ARSA, STS, ARSD, ARSE, ARSF, BAX, BTD, CACNA1A, CRAT, SARDH, GRIN2A, HGF, HLCS, IL15, ITIH1, ITIH3, ITIH4, KIT, P4HA1, PEPD, PIM1, PPP2R1A, PSAP, RRM1, SFTPB, SLC5A5, SLC6A6, SLC7A4, SLC34A1, SLC22A5, SNCB, SRD5A1, STAT5B, TYR, SLC7A5, GGH, VNN2, SLC5A6, P4HA2, SNCAIP, SPOCK2, GLYAT, CRTAP, ATG7, PRDX4, SERINC3 |
1512 | GO:0007519 | 0.00 | 2.16 | 21.28 | 32 | 57 | skeletal muscle tissue development | KLF5, CASQ1, CAV2, CSF1R, DCN, EEF2, EGR2, EP300, GPX1, HLF, HLX, HOXD9, HOXD10, IGFBP5, MEOX2, RB1, RYR1, SOX11, SVIL, TAZ, NR2F2, KCNAB1, CSRP3, SAP30, CFLAR, PHOX2B, COPS2, GTF3C5, HMG20B, VAMP5, VAX1, BVES |
1513 | GO:0009653 | 0.00 | 2.16 | 20.85 | 32 | 60 | anatomical structure morphogenesis | AMHR2, ATM, BCL3, BICD1, BYSL, CST6, S1PR3, ERCC1, EYA4, EYA3, EZH1, F2R, GRID2, GSC2, KRT18, KRT35, CNOT2, PCSK5, PPP2R1B, TP73, TPD52, TSHB, XRCC2, ZNF141, CLTCL1, RGS20, DYRK1B, SOX13, ATP6AP2, TRIM13, IGF2BP3, RCAN3 |
1514 | GO:1903707 | 0.00 | 2.16 | 27.30 | 41 | 73 | negative regulation of hemopoiesis | ANXA1, APCS, BMP4, C1QC, CDK6, CDKN2A, CTLA4, CYLD, ERBB2, PTK2B, FLT3, GABPA, HLX, HES1, IFNA2, IHH, INHA, IRF1, LTF, PF4, RARA, STAT5B, TNFSF4, HIST1H4I, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, INPP4B, TNFSF18, GPR55, CTR9, TRIB1, LRRC17, FSTL3, GAS2L1, TOB2 |
1515 | GO:0035019 | 0.02 | 2.16 | 11.97 | 18 | 32 | somatic stem cell population maintenance | ASCL2, ZFP36L2, CDX2, EPHA1, FGFR3, HES1, RBPJ, KIT, PBX1, RAF1, SALL1, SOX2, SOX9, STAT3, KLF10, PAX8, CUL4A, KLF4 |
1516 | GO:0071479 | 0.02 | 2.16 | 11.97 | 18 | 32 | cellular response to ionizing radiation | ATM, ATR, BCL2L1, CDKN1A, CYBA, GADD45A, DNM2, ELK1, GRB2, IFI16, ITGB1, MGMT, RAD1, RAD51, XRCC5, HMGA2, CLOCK, RAD51AP1 |
1517 | GO:0090263 | 0.00 | 2.15 | 30.67 | 46 | 82 | positive regulation of canonical Wnt signaling pathway | XIAP, ARNTL, COL1A1, CSNK1D, CSNK1G2, DAPK3, DLX5, EDA, FGFR3, FZD2, RBPJ, ILK, SMAD3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, SFRP4, UBB, WNT1, WNT2, WNT2B, FZD5, PSMF1, PSMD6, FRAT1, PSME3, PSMD14 |
1518 | GO:0034599 | 0.00 | 2.15 | 31.31 | 47 | 84 | cellular response to oxidative stress | ABL1, ANXA1, ARG1, ARNT, ARNTL, BCL2, BMP4, BNIP3, CDK2, DNM2, DPEP1, ETS1, ETV5, F3, FANCC, GUCY1B3, HNRNPD, KCNC2, MAP3K5, MGMT, SLC11A2, PRDX1, PENK, PPP5C, PRKAA1, PRKCD, PRKD1, MAPK8, RAD52, RPS3, STAT6, STAU1, TNFAIP3, TRAF2, VRK2, AKR1C3, IL18RAP, KAT2B, AIFM1, KLF4, IL18BP, DHRS2, KLF2, STK25, ARL6IP5, PRDX3, ZNF277 |
1519 | GO:0009199 | 0.00 | 2.15 | 40.77 | 61 | 109 | ribonucleoside triphosphate metabolic process | AK1, AK2, AK4, ALDOB, ALDOC, AMPD2, ARNT, ATP1A2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V0A1, ATP5O, BAD, TSPO, COX4I1, COX8A, COX15, CTNS, CTPS1, ENO2, ENO3, GAPDH, GPD1, HIF1A, HSPA8, IGF1, INS, LDHA, LDHC, OGDH, P2RX7, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PGM1, PPP2R5D, PRKAA1, PRKAG1, SDHC, SNCA, STAT3, TAZ, UQCRC1, UQCRC2, UQCRH, OGT, ATP5J2, HDAC4, SLC25A13, ATP5H, ATP5L |
1520 | GO:0034620 | 0.00 | 2.14 | 28.05 | 42 | 75 | cellular response to unfolded protein | AARS, ACADVL, ADD1, ASNA1, ATF4, BAX, CCND1, TPP1, CTH, DDIT3, EIF2S1, EP300, ERN1, EXTL3, HDGF, IFNG, DNAJB9, PARK2, EIF2AK2, PTPN1, SDF2, SHC1, SSR1, SULT1A3, HSP90B1, WFS1, ZBTB17, ATP6V0D1, VAPB, EIF2AK3, GOSR2, TATDN2, CUL7, BCL2L11, PREB, PDIA6, CREB3, SEC61B, PDIA5, COPS5, KDELR3, SEC63 |
1521 | GO:0045785 | 0.04 | 2.14 | 9.96 | 15 | 27 | positive regulation of cell adhesion | ALOX12, ANGPT1, CD63, ERBB2, NRG1, ITGAV, PTGER4, SELP, CHRD, ADAM9, TNFRSF18, TNFSF18, CYTH3, BAG4, VAV3 |
1522 | GO:0051099 | 0.04 | 2.14 | 9.33 | 14 | 25 | positive regulation of binding | CDK9, KAT2A, HES1, IGF1, ISL1, PARK2, RARA, S100A10, TWIST1, HMGA2, EDF1, KAT2B, KLF4, RAPGEF3 |
1523 | GO:0040011 | 0.00 | 2.14 | 233.70 | 344 | 643 | locomotion | ABL1, ABL2, ACTB, ACTG1, ADCY3, JAG1, AGTR1, ANG, ANXA1, ANXA5, APOA1, APP, ARAF, ASCL1, ASTN1, RERE, ATOH1, ATP1A2, ATP1A4, ATP1B3, ATP2B2, BAX, BBS2, BBS4, DST, BSG, BTG1, TSPO, CACNB3, CACNB4, CALM1, CALM3, CAMK2A, CCK, CD44, CD58, CD72, CD151, CDC42, CDK6, CHN1, CHRM1, AP2S1, CLTA, CCR3, CCR8, ACKR2, COL4A3, COL4A5, COL5A2, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF2RB, CSNK2A1, CSNK2A2, VCAN, CSPG4, CTGF, CTNNA2, DBH, DCC, ACE, DCX, DLG3, DLX5, DNM1, DNAH5, DNAH8, DRD3, DUSP5, TYMP, ECM1, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EGR3, EPHA2, EMP2, CTTN, EMX2, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPS8, ERBB2, EREG, ERG, ETV4, EXT1, F2, FAP, EFEMP1, FCER1G, FGF3, FGF4, FGF5, FGFR3, FGFR4, FPR1, FPR3, FUT8, FYN, GFRA1, B4GALT1, GPM6A, CCR10, XCR1, GPR15, GPX1, GRB2, GRIN2A, ARHGAP35, HIST1H1T, SERPIND1, HCK, HEXB, NR4A1, HRH1, HES1, HSPA8, HSP90AA1, HSP90AB1, IL2RA, IL10, IL12B, ING2, ISL1, ITGA1, ITGA9, ITGAM, ITGAX, ITGB4, KIF5A, KRAS, KRT2, LAMA3, LAMA4, LAMA5, LDHC, ABLIM1, LIMK1, MARK3, SMCP, NRCAM, NRTN, NTRK1, NTRK2, NTN3, OGDH, OLR1, OR1D2, OTX2, P2RY1, PEBP1, PAX3, PCM1, PDE4B, PDE4D, PEX7, PEX13, PIK3C2B, PIK3CB, PPP5C, PRCP, PRKCD, PRKCI, PRKCQ, PRKCZ, PRKX, PSPN, PROC, PSEN1, PSG2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTPN6, PTPRA, RAB1A, RAB13, RAF1, RALA, RASA2, RFX3, RNASE2, RPL24, RPS6KA1, RPS19, RYK, S100A2, S100A8, S100A9, S100A12, SAA4, SCN5A, SCNN1B, CCL22, SDC2, SDC4, SELL, SFTPD, SGK1, SHC1, SIAH1, SIX1, SIX3, SLC9A1, SLC16A1, SLIT3, SNCA, FSCN1, SORD, SOS1, SOS2, SOX1, SOX10, SPN, SPOCK1, SRMS, STAT5B, CDKL5, STK10, XCL2, CNTN2, NR2F1, TMF1, TNP2, TNR, TOP2B, TRPC1, TRPC3, TRPC4, TRPC5, TSC2, TYROBP, UBB, CLRN1, VAV1, VCAM1, ARHGEF5, FOSL1, FGF23, SLC7A5, USP9X, USP9Y, EPX, FZD4, SOX14, CUL3, FOXN1, SORBS2, CNTNAP1, DGKZ, KLF7, DNAH17, UNC5C, DCHS1, PEA15, PHOX2B, RPS6KA4, KALRN, DOK2, USP14, TAOK2, CER1, NRXN3, NRXN1, PSMF1, NRG2, CDC42BPB, FEZ2, SDC3, SLK, ARHGEF11, ZEB2, ELMO1, GAB2, FARP2, KIAA0319, PSMD6, RBX1, RANBP9, GPC6, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN1, ARPC2, AKAP9, ABI2, RASA4, WASF2, TNK2, PSME3, PSMD14, RCAN2, APC2, SPON2, VAV3, CAP1, PROCR, ARPC1A, DPYSL4, PDPN, CXCR6, TBR1, CHL1, GIPC1, CCR9, FRS3, VAX1, SLC7A9 |
1524 | GO:1903052 | 0.00 | 2.14 | 41.51 | 62 | 111 | positive regulation of proteolysis involved in cellular protein catabolic process | CAV3, CCNB1, CDC20, CDC27, CLU, CSNK1D, DAB2, PTK2B, DNAJB2, SMAD7, PARK2, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, RB1, SGTA, SKP1, SUMO3, AURKA, UBB, SUMO1, USP5, CUL3, CUL1, CDC23, CDC16, RGN, PSMF1, RNF14, DLGAP5, RNF40, KEAP1, PSMD6, KCNE2, PSME3, PSMD14, TRIB1, ANAPC10, ARIH2, UBE2C |
1525 | GO:0021537 | 0.00 | 2.14 | 44.88 | 67 | 120 | telencephalon development | ALDH1A3, ANXA3, ASCL1, ATOH1, AVPR2, BAD, BAX, BBS2, BBS4, BMP4, CDK6, COL3A1, CSF1R, CX3CR1, DBI, DCX, DNAH5, LPAR1, EMX1, EMX2, EPHA5, EPHB2, EPHB3, EXT1, EZH1, KAT2A, NRG1, HIF1A, HPRT1, HES1, KCNA1, NTRK2, OGDH, OXTR, PEX13, RELN, PSEN1, PTEN, PTPRS, RAC1, RARA, RARB, RYK, SALL1, SCN5A, SIX3, SLC8A3, SOX2, SRD5A1, SRF, TACC1, CNTN2, NR2F1, TNR, TP73, TSC1, USP9X, NUMB, NRP1, NUMBL, SLIT2, ZEB2, SEMA3A, TACC3, ATG7, TACC2, NRG3 |
1526 | GO:0002562 | 0.04 | 2.13 | 9.35 | 14 | 25 | somatic diversification of immune receptors via germline recombination within a single locus | ATM, CD28, ERCC1, IFNG, IL10, RAG1, RAG2, STAT6, TNFSF4, UNG, WHSC1, RNF8, EXO1, IL27RA |
1527 | GO:0016577 | 0.04 | 2.13 | 9.35 | 14 | 25 | histone demethylation | HSF4, PHF2, KDM6A, UTY, KDM5C, HIST1H4I, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, KDM4A |
1528 | GO:0045682 | 0.04 | 2.13 | 9.35 | 14 | 25 | regulation of epidermis development | ALOX15B, ATOH1, BMP4, CDH3, SFN, HES1, SFRP4, SRSF6, FOXN1, TP63, PTCH2, TRADD, KEAP1, TRIM16 |
1529 | GO:0097061 | 0.04 | 2.13 | 9.35 | 14 | 25 | dendritic spine organization | ABL2, ARF1, CTNND2, EFNA1, CTTN, EPHB1, EPHB2, EPHB3, ITGA3, CAPRIN1, RELN, PTEN, PICK1, BAIAP2 |
1530 | GO:1900543 | 0.04 | 2.13 | 9.35 | 14 | 25 | negative regulation of purine nucleotide metabolic process | ADRA2A, APLP1, TSPO, DRD3, LPAR1, EDNRA, GALR1, GRM8, PALM, SNCA, STAT3, AKAP6, GABBR2, HDAC4 |
1531 | GO:1903309 | 0.04 | 2.13 | 9.35 | 14 | 25 | negative regulation of chromatin modification | BRCA1, DNMT1, DNMT3B, HMGA1, JARID2, PHF2, SET, SNCA, TAF7, TWIST1, UCN, ATG5, KDM4A, ATG7 |
1532 | GO:1903578 | 0.04 | 2.13 | 9.35 | 14 | 25 | regulation of ATP metabolic process | ARNT, TSPO, GPD1, HIF1A, IGF1, INS, P2RX7, PGAM1, PRKAA1, PRKAG1, SNCA, STAT3, OGT, HDAC4 |
1533 | GO:0044281 | 0.00 | 2.13 | 316.88 | 461 | 872 | small molecule metabolic process | AARS, ABCA1, ABCB7, ACO1, ACO2, ACY1, ADCY3, ADCY5, ADCY6, ADCY9, ADH1B, ADRA2A, ADRB2, ADSL, ADSS, AK1, AK2, AK4, ALAD, ALAS1, ALAS2, ALB, ALDH1A1, ALDH3A1, ALDH3A2, AMPD1, AMPD2, ANGPT1, AOC2, APLP1, APLP2, APP, APRT, ARF1, ARG2, ARL2, ARNT, ARSA, STS, ARSD, ARSE, ARSF, ATP1A2, ATP2B2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V0A1, ATP5O, AVPR2, BCHE, BLVRA, BLVRB, BMP1, BNIP2, BSG, TSPO, C3, DAGLA, CA2, CA4, CA5A, CACNB4, CALCR, CAT, CD36, ENTPD2, CD44, CDA, CHIT1, CHRM3, CKM, CNP, COMT, COX4I1, COX5B, COX6A1, COX6B1, COX7C, COX8A, COX15, CPOX, CRH, CSNK1G2, CTGF, CTNS, CTPS1, CYC1, CYP2A6, CYP2A13, CYP2F1, DBH, DBI, DIO2, DIO3, DLG2, DLG3, SARDH, DNM2, DNMT1, DNMT3B, DPEP1, DRD3, DRD5, DTYMK, DUT, TYMP, LPAR1, EDNRA, EPRS, EXT1, EXT2, EXTL1, EXTL3, FABP2, FABP6, FABP7, ACSL1, ACSL4, FAU, FDXR, FSHR, NR5A2, FZD2, GALC, GALR1, GALNS, GHRH, GHRHR, GHSR, GLP1R, GM2A, GNAL, GNAS, GNB1, GNG3, GNG10, GNG11, FFAR1, GPX1, GRM8, GSTM1, GSTM2, GUCA1A, GUCA1B, GUCA2A, GUCA2B, GUCY1B3, GUCY2C, GUCY2F, GUSB, GUCY2D, HARS, HBA2, HEXA, HEXB, HIF1A, HMBS, HMMR, HPRT1, HSD11B1, HSPA8, HSP90AA1, HTR2C, IDH1, IDH3A, IDS, IMPDH1, IMPDH2, INPP4A, INSL3, ITPR1, ITPR2, KCNC2, KCNS3, LUM, MAT2A, CHST6, NUBP1, RPL10A, NTHL1, NTRK1, NTRK2, NUP88, NUP98, OAS2, OAZ1, OAZ2, OMD, OGG1, OGN, P2RX7, P2RY11, P4HA1, PALM, PAM, PDC, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, ENPP3, PEPD, PF4, PFAS, ATP8B1, PIK3C2B, PIK3C3, PIK3CB, PI4KA, PIP4K2A, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKD1, PRPSAP1, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTGDR, PTGER4, PTHLH, RAF1, RAN, RCVRN, RHAG, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, RRM1, RRM2, SDHA, SDHB, SDHC, SDHD, SGSH, SI, ST6GAL1, SLC2A4, SLC2A5, SLC4A1, SLC5A3, SLC5A5, SLC6A6, SLC7A4, SLC9A1, SLC10A1, SLC10A2, SLC16A1, SLC34A1, SLCO1A2, SLC22A1, SLC22A3, SLC22A2, SLC22A5, SMARCD3, SMS, SNAP25, SP1, SRD5A1, STAT3, STAT5B, SULT1E1, STXBP1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, ABCC8, SYT5, TARS, TAZ, TBL1X, TNFRSF1A, TPMT, TNFSF4, TYMS, TYR, TYRP1, UCN, UCP1, UNG, UPP1, UQCRC1, UQCRC2, UQCRH, VIP, VIPR2, WFS1, PAX8, AIMP2, NUP214, PDHX, AAAS, SLC7A5, PIP5K1B, SOAT2, PIK3R3, AGPS, PDE5A, DGAT1, B4GALT4, B4GALT3, PEX11A, SUCLG2, SUCLG1, DPM2, INPP4B, CES2, GGH, HDAC3, CPNE1, MBD4, MGAM, P4HA2, RPL14, PAPSS2, PAPSS1, COX7A2L, VAPB, DHRS3, B4GALT6, B4GALT5, RPL23, LIPG, CIAO1, ABCG2, EIF2AK3, CHST3, AKAP6, PSMF1, TBPL1, EEF1E1, TP53I3, ATP5J2, MINPP1, GABBR2, AKAP12, GUCA1C, NUP155, HS2ST1, NUP93, HDAC4, EIF4A3, PTDSS1, SPOCK2, KEAP1, PSMD6, FIG4, HS3ST4, HS3ST3B1, HS3ST3A1, HS3ST1, GNE, ABCC5, COL4A3BP, NUBP2, SLC25A15, PSME3, CALCRL, PSMD14, GLYAT, RAMP2, B3GNT3, RAPGEF3, CDIPT, SEC24B, ATP5H, SEC23A, CAP1, CRTAP, CARM1, ATG7, PRDX4, SLCO1B1, PDPN, ATP5L, FARS2, CERS1, NUP50, AHCYL1, SEC24A, PDE10A, SLC26A1, DHRS4, SERINC3, ACOT2, UQCR11, SLC35D2, RAPGEF4, KERA, NUPL2, RPP14, NUDT4, TREH, RPL35 |
1534 | GO:0048813 | 0.00 | 2.13 | 25.43 | 38 | 68 | dendrite morphogenesis | ABL2, RERE, CACNA1A, CHRNB2, CTNNA2, CTNND2, DCX, EFNA1, EPHB1, EPHB2, EPHB3, FYN, HPRT1, ILK, ITGB1, CAPRIN1, MAP6, SLC11A2, RELN, PTEN, PTPRD, RAC1, RAP2A, SDC2, SGK1, CDKL5, STK11, PICALM, KLF7, NUMBL, RAPGEF2, CUL7, FARP1, SEMA3A, BAIAP2, SEMA4D, CIT, IL1RAPL1 |
1535 | GO:0045930 | 0.00 | 2.13 | 55.73 | 83 | 149 | negative regulation of mitotic cell cycle | ABL1, ATM, ATRX, CCND1, BCL2, BCL2L1, BMP4, BUB1B, CCNB1, CDC20, CDC27, CDK2, CDKN1A, CENPF, CHEK1, ATF2, CSNK2A1, CSNK2A2, BRINP1, DUSP1, FGFR3, GAS1, PRMT2, SMAD3, FOXO4, OVOL1, PRCC, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, RB1, RPA2, RPL24, SETMAR, SMARCA4, TOP2A, TOP2B, TP73, TTK, UBB, XPC, ZNF207, HMGA2, SMC1A, DGKZ, TP63, CDC23, CRADD, CDC16, ZW10, SLC9A3R1, PSMF1, MAD2L1BP, PSMD6, TOM1L1, PSME3, PSMD14, CTDSPL, ANAPC10, MAD2L2, UBE2C, ZWINT, CHEK2 |
1536 | GO:0070838 | 0.00 | 2.13 | 80.79 | 120 | 216 | divalent metal ion transport | ABL1, ADRA2A, ADRB2, ANXA5, ANXA6, ATP1A2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, BAX, BCL2, BMP4, TSPO, CACNA1A, CACNA1B, CACNA2D1, CACNB3, CACNB4, CALM1, CALM3, CAMK2A, CASQ1, CASQ2, CAV3, CD4, CHRNB2, CLCA1, CCR5, CRH, CTGF, CYBA, DDIT3, DIAPH1, EDNRA, F2, F2R, PTK2B, FYN, GAS6, GCG, GJA4, GPM6A, XCR1, FFAR1, GRIN2A, GSTM2, HRC, HTR2C, ICAM1, IGF1, IL13, ITGAV, ITPR1, ITPR2, KCNJ2, KCNN4, SLC11A2, NTSR1, P2RX1, P2RX3, P2RX4, P2RX5, P2RX7, PAWR, PDE4B, PDE4D, PLN, PRKCE, PRKD1, PSEN1, PTPN6, RCVRN, RYR1, RYR2, RYR3, S100A1, CCL21, XCL1, SEMG1, SLC8A3, SLC9A1, SLC11A1, SLN, SNCA, SPINK1, STC1, TPT1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, SUMO1, UCN, TRPV1, WFS1, SLC30A2, SLC30A3, SLC30A4, TUSC3, TRPA1, RGN, SLC24A1, GSTO1, AKAP6, ATG5, KCNE2, KCNE3, CALCRL, RAMP2, RAMP3, TRDN, CACNG2, RAPGEF3, SLC30A9, CREB3, CHERP, IL1RAPL1, CORO1A |
1537 | GO:0050714 | 0.00 | 2.13 | 42.26 | 63 | 113 | positive regulation of protein secretion | ABAT, ABL1, ABL2, ACHE, AGTR2, ALOX15B, ANG, ARF1, BAD, BLK, BMP6, CASP1, CASP5, CD38, CD58, CFTR, CRH, CSF1R, F2R, F2RL1, FGA, FGG, FGR, GCG, GLUD1, GLUL, GPLD1, GPR27, FFAR1, HIF1A, IFNG, IGF1, IL1A, IL1B, IL10, IL13, IL17A, INS, ISL1, KCNN4, OXCT1, P2RX7, PAEP, PFKFB2, PPID, PRKCE, PRKCQ, PRKCZ, PTGER4, TRPM2, TWIST1, TNFSF4, TNFRSF4, NR1H2, VEGFC, ADAM9, IL1RL1, STXBP5L, C2CD2L, TRIM16, SEC24A, CAPN10, GLMN |
1538 | GO:0032970 | 0.00 | 2.13 | 70.69 | 105 | 189 | regulation of actin filament-based process | ABL1, ABL2, ADD1, APOA1, ARF1, ARF6, ARHGAP6, ATP1A1, ATP1A2, BBS4, BST2, CAPG, CAPZA1, CAPZB, CAV3, CFL2, CNN2, CSF1R, CTGF, CTSV, DAPK3, DSC2, DSP, S1PR1, LPAR1, EFNA5, CTTN, EPHA1, EPHA5, EPS8, F2RL1, PTK2B, GATA4, GJA5, GRB2, HCK, HCLS1, HRG, ICAM1, ILK, KCNJ2, LIMK1, TACSTD2, SMAD3, NTF3, NTRK3, PAM, PARK2, PDE4B, PDE4D, PFN1, PFN2, PLN, PRKCD, PRKCE, PRKCQ, PTGER4, RAC1, RDX, RYR2, S100A10, SCN5A, CCL21, CCL24, SDC4, SLC9A1, FSCN1, STC1, TAC1, TMOD1, TNNC1, TNNT2, TSC1, SUMO1, VIL1, WNT11, ALMS1, ARHGEF5, CSRP3, WASF1, SEMA5A, LATS1, ITGB1BP1, SLIT2, PICK1, BAG4, SEMA3E, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, ABI2, WASF2, SORBS3, RAPGEF3, CDC42EP2, BAIAP2, ARPC1A, ARFGEF1, CDC42EP3, AVIL, CORO1A, FZD10 |
1539 | GO:0032092 | 0.02 | 2.13 | 12.72 | 19 | 34 | positive regulation of protein binding | ABL1, ABL2, ADD1, BMP4, KRIT1, EP300, EPB41, GCG, HSP90AB1, RAN, RFNG, TRAF2, VTN, NRP1, ARHGEF7, TNFSF18, EIF2AK3, TRAF4, RAPGEF2 |
1540 | GO:0002440 | 0.00 | 2.12 | 22.79 | 34 | 61 | production of molecular mediator of immune response | KLK3, BTK, CD28, CD36, CD37, CLC, ERCC1, F2RL1, FCER1G, GAS6, FFAR3, HPX, IFNG, IL13, KIT, PGC, PRKCZ, SLC11A1, STAT6, TRAF2, TNFSF4, TNFRSF4, UNG, WHSC1, FZD5, RNF8, EXO1, IL27RA, ATG5, TRIL, SPON2, TNFSF13B, TRAF3IP2, MALT1 |
1541 | GO:0007420 | 0.00 | 2.12 | 37.40 | 56 | 102 | brain development | AK2, AK4, ATM, ATP2B1, BCR, BID, BMPR2, BOK, BRCA1, BRCA2, BYSL, CD9, CENPF, CLN5, CTNS, DNMT1, S1PR1, EML1, EPHA7, ACSL3, AFF2, GABRA5, HMGCS1, HMGCS2, HMX2, HNMT, IGF1R, KCNK3, CITED1, NTF3, OXCT1, PAFAH1B2, PAFAH1B3, SLC6A11, SMARCA1, STAR, STXBP3, SYT1, SYT4, TULP3, UBE3A, ZIC1, ZIC2, KCNAB1, ITGA8, UNC5C, ATP6V0D1, BAG3, AATK, SNPH, BCL2L11, ABCB6, COX17, TSPAN2, RAPGEF3, VAX1 |
1542 | GO:0051240 | 0.00 | 2.12 | 206.98 | 304 | 564 | positive regulation of multicellular organismal process | ABAT, ABL1, ABL2, ACACB, ACVR1, ACVR2A, ACVR2B, ACVRL1, JAG1, ALOX15B, ANGPT2, ANXA1, BIRC2, BIRC3, APOH, ARF1, ARNT, ASCL1, ATF4, ATOH1, ATP2A1, AXL, BAD, ADGRB1, ADGRB2, CCND1, BCL3, PRDM1, BMP1, BMP6, BMPR1A, BRCA1, BTG1, BTK, TSPO, C3, CASP1, CASP5, RUNX2, CBLB, CD3E, CD4, CD6, CD28, CD80, CD86, TNFRSF8, CD36, CD58, CDC20, CDC42, CDK9, CHRM3, CHUK, CLU, CCR3, CNR1, COL1A1, ATF2, CRH, CRX, CSF1R, CTH, CX3CR1, DAB2, BRINP1, DDIT3, DHX9, DLX5, DNMT3B, DPYSL3, DRD3, ECM1, LPAR1, EDNRA, EFNA5, EGR3, EIF4G1, CTTN, EP300, EPHA1, EPHB1, EPHB2, EPHB3, EREG, ETV5, F2, F3, F7, FCER1G, FGR, FLT1, FLT3LG, FYN, GALR1, GAS6, GFAP, GNAS, GOLGA4, SFN, FFAR3, RAPGEF1, GRN, ARHGAP35, HCLS1, HLX, FOXA2, HOXD3, HES1, IFI16, IGF1, IHH, IL1A, IL1B, IL2RA, IL10, IL12RB2, IL13, IL17A, ILK, IDO1, INHA, IRAK1, IRF1, IRF5, ISL1, ITGA5, ITGB1, JUND, KISS1, KIT, KNG1, LIMK1, LTF, LUM, CAPRIN1, SMAD1, SMAD3, CD46, KITLG, NRCAM, NTF3, NTRK1, NTRK2, NTRK3, OPA1, OTX2, P2RX7, P2RY1, PAEP, SERPINE1, PALM, PARK2, PCP4, PDE3A, PDE4B, SERPINF1, PENK, PF4, PRG2, PRKCI, PRKCQ, PRKCZ, MAPK8, EIF2AK2, RELN, PSEN1, PTGIS, PTN, PTPRD, RAG1, RAG2, RARA, RARB, RB1, RFX3, RHEB, RPS19, S100A9, SALL1, SERPINB3, CCL20, CCL24, XCL1, CX3CL1, SDCBP, SEC14L1, SELP, SFRP4, SRSF6, SGK1, SLC9A1, SLC11A1, SLC22A5, SMARCD3, SNAI1, SOD1, SOX2, SOX10, SOX11, SPINT1, SPN, SRF, TRIM21, STAR, STAT6, AURKA, CDKL5, STK11, SYT1, SYT4, ADAM17, TAL1, ZEB1, KLF10, TMF1, TNFAIP3, TP73, TPBG, NR2C2, TRAF2, TRPC3, TWIST1, TNFSF4, UBB, UNG, NR1H2, USF1, VEGFB, TRPV1, WHSC1, WNT1, WNT11, XRCC2, XRCC5, ZIC2, ZNF16, RNF112, PAX8, FZD5, RND2, EPX, FOXN1, OGT, IKBKG, CAMK1, AP3B1, TP63, PTCH2, NUMB, PDE5A, VAMP8, SERPINB7, TRADD, RIPK1, TNFSF9, RIPK2, CPNE1, PHOX2B, AP3D1, CBFA2T2, IL1RL1, ARHGEF2, NUMBL, PDLIM7, SLIT2, NRXN3, NRXN1, LIPG, GSTO1, EIF2AK3, IL27RA, ADAMTS1, RAPGEF2, RIMS2, IST1, CUL7, ZEB2, FIG4, RBM19, ATP6AP2, OLIG2, TRIB1, RAMP2, KATNB1, TRDN, ABCA7, HMG20B, PRG3, RAPGEF3, SPON2, BAIAP2, STK25, SEMA4D, ARFGEF2, TRIM16, DMRT2, AVIL, TOB2, MALT1, STMN2, IL1RAPL1, GLMN, HHLA2 |
1543 | GO:1903900 | 0.00 | 2.12 | 36.28 | 54 | 97 | regulation of viral life cycle | ADAR, ADARB1, APCS, BCL2, BST2, CAV2, CCNH, CCNT1, CD28, CDK9, CHD1, DDX5, EP300, STOM, ERCC3, NR5A2, GTF2F1, IFI16, IFIT1, IFNA2, ILF3, ISG20, JUN, LTF, OAS3, PARK2, PPIB, PPID, EIF2AK2, REST, SLPI, SMARCA4, SP1, SP100, SRPK2, TRIM21, SSRP1, STAU1, SUPT4H1, TMPRSS2, TOP2A, TSG101, TRIM25, HMGA2, CTDP1, VAPB, TRIM13, TNIP1, IFITM3, PPIE, PPIH, TRIM38, IFITM2, SUPT16H |
1544 | GO:0001764 | 0.00 | 2.12 | 29.55 | 44 | 79 | neuron migration | ASCL1, ASTN1, ATOH1, AXL, BAX, BBS4, CCK, COL3A1, DCC, DCX, FYN, GAS6, GPM6A, NRG1, ITGA3, NRCAM, NTRK2, NTRK3, PCM1, PEX7, PEX13, RELN, PSEN1, PTK2, SOX1, SPOCK1, SRF, STAT3, CDKL5, CNTN2, NR2F1, NR2F2, TOP2B, TWIST1, USP9X, SOX14, NRP1, PHOX2B, RAPGEF2, KIAA0319, SEMA3A, NRG3, CHL1, VAX1 |
1545 | GO:1900180 | 0.01 | 2.12 | 16.74 | 25 | 45 | regulation of protein localization to nucleus | AGTR2, ANGPT1, BCL3, CD36, CDKN1A, CYLD, GAS6, GNAQ, IL10, TONSL, OGG1, PRDX1, PPM1A, PPM1B, SFRP5, AKAP1, FZD7, DYRK2, RGS20, SLC9A3R1, LITAF, KEAP1, APC2, TACC3, CREB3 |
1546 | GO:0009887 | 0.00 | 2.12 | 42.79 | 64 | 117 | organ morphogenesis | ACTG2, APLP1, BBS2, CDX2, CDX4, COL3A1, CRKL, CRX, CTNNA2, DCN, DSP, E2F4, S1PR1, ELN, EMX1, EP300, EREG, ERG, FGD1, FLI1, NR5A2, GAA, GAMT, GATA6, GJA5, GPC3, HCCS, NRG1, IGF2, ILK, ITGAX, JUN, ABLIM1, SMAD7, NTF4, SIX6, PAX4, PBX1, PRKX, PSPN, PTEN, PTK2, RFNG, RYR1, SFTPB, SLIT3, SMARCD3, SNAI1, SOX3, TNNC1, TNNI3, TNNT2, VEGFC, WHSC1, CUL1, FOXN1, DCHS1, ADAM15, ALDH1A2, BAZ1B, ONECUT2, COL4A3BP, TBR1, TREH |
1547 | GO:1903533 | 0.00 | 2.12 | 61.34 | 91 | 164 | regulation of protein targeting | ACTL6A, AGTR2, AKT2, ANGPT1, BCL3, BMP4, BMP6, BMPR1A, BNIP3L, BRCA1, CD36, CDH1, CDKN1A, CDKN2A, CSNK2A2, CTSK, CYLD, DAB2, EDA, STOM, ERBB2, GAS6, KAT2A, GDI1, GNAQ, GPR26, HCLS1, NRG1, HNMT, HES1, HSP90AB1, IGF1, IL1B, IL10, IL12B, IL18, ITGAX, KCNE1, KPNA1, IPO5, SMAD3, TONSL, OGG1, PRDX1, PARK2, PPM1A, PPM1B, PPP3R1, PRKCD, PRKCQ, RAC2, RNASE2, SFRP5, SLC9A1, SREBF1, TRIP6, U2AF1, UBE2L3, ZIC1, ZBTB17, FZD5, AKAP1, BAP1, FZD7, DYRK2, OGT, RGS20, RUVBL1, TNFSF14, HDAC3, CDKL2, SEMA5A, ITGB1BP1, SLC9A3R1, AKAP6, LITAF, BAG4, ATG13, KEAP1, C2CD5, FAM20B, SAE1, NUTF2, APC2, PEMT, ARIH2, TACC3, CREB3, CHERP, RBCK1, EDAR |
1548 | GO:0009126 | 0.00 | 2.12 | 47.12 | 70 | 126 | purine nucleoside monophosphate metabolic process | ADSL, ADSS, AK1, AK2, AK4, ALDOB, ALDOC, AMPD1, AMPD2, APRT, ARNT, ATP1A2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V0A1, ATP5O, BAD, TSPO, COX4I1, COX8A, COX15, CTNS, DLG2, DLG3, ENO2, ENO3, GAPDH, GPD1, HIF1A, HPRT1, HSPA8, IGF1, IMPDH1, IMPDH2, INS, LDHA, LDHC, OGDH, P2RX7, PFAS, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PGM1, PPP2R5D, PRKAA1, PRKAG1, SDHC, SNCA, STAT3, TAZ, UQCRC1, UQCRC2, UQCRH, OGT, ATP5J2, HDAC4, SLC25A13, ATP5H, ATP5L |
1549 | GO:0045935 | 0.00 | 2.11 | 327.28 | 472 | 876 | positive regulation of nucleobase-containing compound metabolic process | ABCA1, ACVR1, ACVR2A, ACVRL1, ADM, ADRB2, JAG1, AGTR2, AKT2, ALK, ANXA3, APP, AREG, PHOX2A, ARNT, ARNTL, ASCL1, ATF4, ATM, RERE, ATOH1, ATR, ATRX, AVP, AVPR2, BACH1, BCL3, BMP3, BMP4, BMP6, BMPR1A, BMPR2, BRCA1, BRCA2, BRDT, ZFP36L2, KLF5, BTK, CALCR, CALM1, CALM3, CAMK4, CAMK2A, CAT, RUNX2, CBFB, CCNB1, CCNC, CCNE1, CCNH, CCNT1, CCNT2, CCT6A, CD3D, CD28, CD80, CD86, TNFSF8, CD38, CD81, CDC42, CDH1, CDK2, CDK8, CDK9, CDKN2A, CDX1, CDX2, CDX4, CEBPE, CGA, CHD1, CHEK1, CHUK, CLU, COL1A1, CREB1, ATF2, CREBL2, CRH, CRX, CTH, DAB2, DCN, DDIT3, DDX5, DKC1, DLX5, DNM2, DRD3, DRD5, ARID3A, E2F4, EBF1, EDA, S1PR1, EDNRA, EGR2, ELK1, EN1, EP300, EPHA5, ERBB2, ERCC1, EREG, ERCC3, ERCC6, ESR1, ESRRG, ETS1, ETV4, ETV5, ETV6, EVX1, EYA1, EYA3, EZH1, F2R, F2RL1, PTK2B, FGF4, FGF7, FGFR4, FLI1, FSHB, FSHR, NR5A2, NR5A1, FZD2, GABPA, GALR1, GATA4, GATA6, GCG, KAT2A, NR6A1, GHRH, GHRHR, GLP1R, GNAL, GNAS, GPD1, GTF2F1, GUCA1A, GUCA1B, GUCA2A, GUCA2B, H2AFZ, HCLS1, HEXB, HGF, NRG1, HHEX, HIF1A, HMGN1, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HNRNPD, HOXC11, HOXD8, HOXD9, HOXD10, PRMT2, HES1, HSF4, HSPA8, ICAM1, IFI16, IFNA2, IFNG, IGBP1, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL1B, IL10, IL17A, ILF3, ILK, ING2, INS, INSIG1, INSL3, IRAK1, IRAK2, IRF1, IRF2, IRF5, ISL1, JUN, JUND, KIT, KRAS, ABLIM1, LMO1, LTF, LUM, EPCAM, SMAD1, SMAD3, SMAD7, SMAD9, MEOX2, KITLG, MGMT, CIITA, AFF1, FOXO4, CITED1, PPP1R12A, NRL, YBX1, NTF3, NTRK1, NTRK2, NVL, SIX6, OTX1, OTX2, P2RX7, P2RY1, P2RY11, SERPINE1, PARK2, PAX3, PAX9, PBX1, PCK1, PER1, PF4, PGR, PHF2, PRRX1, PPM1A, PPP3R1, PRKAA1, PRKCI, PRKD1, PRKCQ, PRKCZ, EIF2AK2, RELN, PSEN1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PTEN, PTGER4, PTHLH, RAC1, RAD21, RAD51, RAF1, RAN, RARA, RARB, RB1, RBL1, RCVRN, RELB, UPF1, REST, RFX3, RFXAP, RLF, RNF6, RPS6KA1, RREB1, RXRA, RXRG, S100A8, S100A9, S100A12, SALL1, SETMAR, SHC1, SIX1, SIX3, SLC9A1, SLC11A1, SMARCA1, SMARCA2, SMARCA4, SMARCC2, SMARCD1, SMARCD3, SNAI1, SNRNP70, SOX1, SOX2, SOX9, SOX10, SOX11, SOX12, SP1, SP100, SREBF1, SRF, SRY, TRIM21, SSRP1, STAT1, STAT3, STAT4, STAT5B, STAT6, SUPT4H1, SUPV3L1, TAF2, TAF7, TAL1, TBL1X, TBP, HNF1A, ZEB1, NR2F2, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C2, TRAF1, TRAF2, CCT3, TSC2, TWIST1, TNFSF4, UBB, UBE3A, UBTF, UCN, UNG, NR1H2, USF1, VIP, VIPR2, WFS1, WHSC1, WNT1, WNT2, WNT11, YY1, ZFP36, ZIC1, ZIC2, ZNF711, CNBP, ZSCAN21, TRIM25, ZNF148, ZBTB17, ZXDA, PAX8, FZD5, BRPF1, ARHGEF5, CSRP3, FOSL1, FGF23, HMGA2, NRIP1, PICALM, FZD4, FZD7, FZD8, OGT, ITGA8, IKBKG, CAMK1, MAPKAPK5, STK16, KLF7, RFXANK, TP63, TRADD, EDF1, RIPK1, RIPK2, TRIM24, CFLAR, HDAC3, KAT2B, BUD31, PHOX2B, RPS6KA4, TNFSF18, RNF8, BAZ1B, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, AURKB, CCPG1, ITGB1BP1, KLF4, HMGN3, CNOT8, HAND1, EIF2AK3, FHL5, ONECUT2, GTPBP1, CLOCK, AKAP12, RNF14, GUCA1C, CTR9, ZNF516, HDAC4, BCLAF1, MAML1, ARHGEF11, ZEB2, RNF10, NR1I3, NR1H4, NR1D2, NR2E3, RAD50, RNF41, CALCRL, TRIM13, SF3B4, RAMP2, FSTL3, TNIP1, IKZF1, TRIM22, KLF2, CITED2, RAPGEF3, RBM14, MAD2L2, SLC30A9, TRIM38, CAP1, CREB3, DEAF1, CCT7, CCT4, CCT2, USP16, ERLIN1, RBCK1, ARID3B, TRIM16, DMRT2, CTCF, TBR1, STAG2, RAI1, RUVBL2, ARID5A, MALT1, PRDX3, COPS5, PIM2, WWP2, ERLIN2, PSIP1, SUPT16H, CHEK2 |
1550 | GO:0005996 | 0.00 | 2.11 | 38.31 | 57 | 103 | monosaccharide metabolic process | ACACB, ADRA1B, AKT2, BAD, CACNA1A, CALM1, CALM3, FUT6, FUT8, SLC37A4, GAA, GALE, GALK1, GALK2, GCGR, B4GALT1, GLB1, GPLD1, GYS2, FOXA2, ONECUT1, IGF1, IGF2, IGFBP3, IGFBP5, INPPL1, KCNJ11, KHK, LDHA, MAN2B1, PARK2, PDK4, PFKFB2, PHKA1, PHKA2, PHKB, PHKG1, PPP2R5D, PRKAA1, PRKCE, PYGB, PYGL, PYGM, RPE, UBB, UGDH, UGP2, UGT2B4, UGT2B7, USF1, EPM2A, DYRK2, EPM2AIP1, XYLB, SORBS1, FUT9, UGT2A1 |
1551 | GO:0043393 | 0.01 | 2.11 | 16.78 | 25 | 45 | regulation of protein binding | ADRB2, ANGPT1, APLP2, APP, ATR, CDC42, DAB2, GOLGA2, IFIT1, IL10, LRPAP1, PEX14, PRKCD, MAPK8, PSEN1, SLPI, SMARCD3, AURKA, CAMK1, ADAM15, AURKB, ITGB1BP1, HDAC4, CARM1, RUVBL2 |
1552 | GO:0030522 | 0.00 | 2.11 | 58.72 | 87 | 157 | intracellular receptor signaling pathway | NR0B1, ALOX15B, BIRC2, BIRC3, XIAP, APP, ARNT, ARNTL, BCL2, BCL2L1, BRCA1, CASP1, CCNE1, CHUK, CRY1, CRY2, CYLD, CYP24A1, DAB2, DDX5, EP300, ESR1, ESRRG, FLT1, NR5A2, NR5A1, NR6A1, GHRHR, NR4A1, HNF4G, PRMT2, HSP90AB1, IGF1, IRAK1, IRAK2, ISL1, SCGB2A1, CNOT2, P2RX7, PER1, PGR, PIM1, PPP5C, PRCP, PTGIS, RAN, RARA, RARB, RB1, RNF6, RXRA, RXRG, SEC14L1, SMARCA4, SP100, STAT3, TAF7, NR2F1, NR2F2, TNFAIP3, NR2C1, TWIST1, UBB, UBE3A, NR1H2, NRIP1, IKBKG, AKR1C3, RIPK2, TRIM24, ALDH1A2, BUD31, RQCD1, DHRS3, CLOCK, RNF14, NR1I3, NR1H4, NR1D2, NR2E3, HDAC6, CITED2, RBM14, CARM1, TRIM16, TXNIP, BRD8 |
1553 | GO:0050769 | 0.02 | 2.11 | 14.07 | 21 | 38 | positive regulation of neurogenesis | TSPO, CX3CR1, GFAP, HIF1A, HES1, IL1B, KIT, NTF3, RHEB, CX3CL1, SMARCD3, SOX10, SPINT1, STAR, TP73, VEGFC, XRCC2, XRCC5, NUMB, OLIG2, SEMA3A |
1554 | GO:0048565 | 0.02 | 2.11 | 13.43 | 20 | 36 | digestive tract development | ASCL1, PRDM1, KLF5, CCNB1, CDKN1A, CDX2, COL3A1, GATA6, HRH2, HES1, ITGB4, KIT, OXTR, PCSK5, RARB, RB1, SALL1, TYMS, DCHS1, NR1H4 |
1555 | GO:0061136 | 0.04 | 2.11 | 10.07 | 15 | 27 | regulation of proteasomal protein catabolic process | GPX1, PSMC1, PSMC2, PSMC3, PSMC4, PSME1, PSME2, TMF1, UBB, PSMF1, RNF40, KCNE2, PSME3, PSMD14, USP19 |
1556 | GO:1901605 | 0.00 | 2.11 | 46.45 | 69 | 125 | alpha-amino acid metabolic process | ADSS, ARG2, ASS1, CKM, CTPS1, DNMT1, DNMT3B, FAU, GAMT, GATM, LIPC, RPL10A, P4HA1, PFAS, PSPH, PYCR1, ALDH18A1, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, SLC1A3, SMS, STAT5B, TYR, P4HA2, RPL14, RPL23, EIF4A3, PTDSS1, NR1H4, GLYAT, PEMT, CRTAP, PRDX4, AHCYL1, SERINC3, RPL35 |
1557 | GO:0009582 | 0.00 | 2.11 | 44.51 | 66 | 119 | detection of abiotic stimulus | ABCA4, APOA1, ATP2B2, OPN1SW, CACNB4, CALM1, CALM3, CAV3, AKR1C4, CHRM1, CLPS, CNGA1, COL11A1, EPHB1, GPC4, FYN, OPN1MW, GPC3, GNAQ, GNAT1, GNAT2, GNB1, GNGT1, GNGT2, GUCA1A, GUCA1B, GUCY2F, GUCY2D, IGF1, KCNA1, KIT, NTRK1, NTSR1, PAWR, PDC, PDE6G, PRKCQ, RBP1, RBP2, OPN1LW, RCVRN, RGR, RPE65, RS1, SAG, SDC2, SDC4, SLC12A2, SOX2, TAC1, TRPC3, TULP1, TRPV1, CSRP3, AKR1C3, TRPA1, SEMA5A, UNC119, SLC24A1, DHRS3, GUCA1C, SDC3, PIEZO1, NR2E3, GPC6, RRH |
1558 | GO:0007589 | 0.04 | 2.10 | 10.07 | 15 | 27 | body fluid secretion | COPA, CYBA, GUCA1B, GUCA2B, P2RY2, PRKCE, PTGER4, SLC22A2, TP73, UCN, NR1H2, VIP, VAMP8, ATG5, ATG7 |
1559 | GO:0022904 | 0.00 | 2.10 | 23.56 | 35 | 63 | respiratory electron transport chain | ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP5O, COX4I1, COX5B, COX6A1, COX6B1, COX7C, COX8A, COX15, CYC1, GPD1, SDHA, SDHB, SDHC, SDHD, SLC1A3, SNCA, TAZ, UCP1, UQCRC1, UQCRC2, UQCRH, SLC25A12, COX7A2L, ATP5J2, SLC25A13, ATP5H, ATP5L, UQCR11 |
1560 | GO:0019724 | 0.04 | 2.10 | 10.08 | 15 | 27 | B cell mediated immunity | BCL3, SERPING1, C1QA, C1QB, C1QC, C1S, C7, CLU, CR2, ERCC1, IL13RA2, CD46, PRKCD, RNF8, EXO1 |
1561 | GO:0045639 | 0.01 | 2.10 | 16.83 | 25 | 45 | positive regulation of myeloid cell differentiation | ACVR2A, JAG1, ARNT, ATP6AP1, CA2, CREB1, CSF1R, ETS1, GNAS, HCLS1, HIF1A, IFNG, IL12B, IL17A, JUN, KITLG, PF4, RB1, TAL1, KLF10, ZNF16, OGT, RIPK1, TRIB1, IKZF1 |
1562 | GO:0044770 | 0.00 | 2.10 | 59.42 | 88 | 160 | cell cycle phase transition | ACVR1, BACH1, BCAT1, BID, CAMK2A, CCNE1, CCNH, CDC25A, CDC25C, CDK3, CDK6, CDKN2A, CHEK1, CKS1B, CSNK1D, GADD45A, DHFR, DYNC1H1, DYNC1I2, DNM2, E2F4, E2F6, EIF4E, EIF4EBP1, EP300, EPS8, ERCC3, GFI1, HSP90AA1, ITGB1, PPP1R12A, PPP1R12B, NUMA1, ORC1, ORC2, ORC4, ORC5, PCM1, PCNA, CDK14, PIM1, PPP2R1A, PPP2R2A, PPP6C, PRIM2, PRKAR2B, PRKCQ, PTPN6, RPA3, RPL24, RPS6KB1, RRM2, SIX3, SKP1, AURKA, ADAM17, TAF2, TPD52L1, TUBA4A, TUBG1, TYMS, UBE2L3, WEE1, XPC, ALMS1, TUBA1A, CUL2, CUL1, KLF11, PPM1D, CDC14A, SSNA1, DYNLL1, LATS1, CCNB2, CCNE2, CTDP1, MAD2L1BP, CEP135, CKAP5, AKAP9, TUBGCP3, PDPN, KHDRBS1, ARPP19, TUBGCP2, DBF4, PIM2 |
1563 | GO:0002287 | 0.04 | 2.10 | 10.10 | 15 | 27 | alpha-beta T cell activation involved in immune response | ANXA1, BCL3, CD80, CD86, HLX, IFNG, IL12B, PRKCZ, PTGER4, RARA, RELB, STAT6, TNFSF4, RIPK2, TNFSF18 |
1564 | GO:0007031 | 0.04 | 2.10 | 10.10 | 15 | 27 | peroxisome organization | ABCD1, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX14, PIK3C3, PEX19, ABCD3, PEX5, PEX11A, PEX16, ACOT8 |
1565 | GO:0061077 | 0.04 | 2.10 | 10.10 | 15 | 27 | chaperone-mediated protein folding | BAG1, CANX, CLU, CSNK2A1, FKBP3, FKBP5, HSPA8, PPIB, PPID, PEX19, DNAJC7, FKBP6, TRAP1, CRTAP, CCT2 |
1566 | GO:0010604 | 0.00 | 2.10 | 23.74 | 36 | 69 | positive regulation of macromolecule metabolic process | AREG, ATR, ZFP36L2, CCT6A, CD63, DKC1, ERCC1, EYA3, FCER2, MGMT, NVL, RAD51, UPF1, SELE, SETMAR, SUPV3L1, NR2F1, CCT3, TNFSF4, UNG, WHSC1, DYRK2, SERPINB7, RNF8, AURKB, CNOT8, PICK1, GTPBP1, EPM2AIP1, HDAC6, RAMP3, CCT7, CCT4, CCT2, SORBS1, BVES |
1567 | GO:0006936 | 0.00 | 2.10 | 29.60 | 44 | 80 | muscle contraction | ACTG2, ANXA1, ARG2, ATP1A3, BBS2, BDKRB2, CHRNB2, CHUK, LTB4R, DTNA, EDN3, EDNRA, EEF2, GAA, GAMT, GLRA1, ITGA1, KCNE1, KCNH2, KCNJ12, KNG1, P2RX3, PGAM2, RPS6KB1, RYR1, SCN4B, SCN7A, SRSF1, SGCA, SMTN, SNTB1, TAZ, VEGFB, VIPR1, TRPV1, CSRP3, DYSF, NUP155, ARHGEF11, KCNE2, COL4A3BP, SORBS3, TRDN, SORBS1 |
1568 | GO:0051216 | 0.00 | 2.09 | 20.90 | 31 | 56 | cartilage development | BBS2, BMP3, BMP8B, BMPR1A, SERPINH1, CD44, COL1A1, COL9A1, COL11A1, COMP, EVC, FGF4, FGFR3, GNAS, GPLD1, HIF1A, HOXD3, LUM, SMAD9, PRRX1, SNAI1, SRF, STC1, ZEB1, TYMS, WNT2B, HMGA2, CER1, HAND1, EIF2AK3, ARID5A |
1569 | GO:0051351 | 0.00 | 2.09 | 27.68 | 41 | 74 | positive regulation of ligase activity | BMI1, CCNB1, CDC20, CDC27, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, SKP1, UBB, UBE2L3, XRCC4, CUL1, CDC14B, CDC23, CDC16, PSMF1, PSMD6, PSME3, PSMD14, ANAPC10, UBE2C |
1570 | GO:1904892 | 0.00 | 2.09 | 27.68 | 41 | 74 | regulation of STAT cascade | CHAD, CISH, CNTF, CSF1R, CTF1, DCN, F2R, PTK2B, FGFR3, FLT3, FYN, GFRA2, GP1BA, HCLS1, HPX, HES1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IL10, IL12B, IL13, IL15, IL18, ISL1, KIT, PPP2R1A, PTGER4, TNFRSF1A, TNFRSF18, TNFSF18, SOCS3, CRLF1, SOCS6, SH2B2, IL24 |
1571 | GO:0007167 | 0.00 | 2.09 | 56.24 | 84 | 157 | enzyme linked receptor protein signaling pathway | ACVR1, ACVR2A, ACVR2B, ACVRL1, AMHR2, XIAP, BMP1, BMP3, BMP4, BMP6, BMP8B, BMPR1A, CAV3, CCNC, CCNT1, CCNT2, CDK8, CDK9, COL3A1, CTF1, DAB2, DLX5, DNM2, E2F4, FBN1, FSHB, FUT8, GAS6, GATA4, GATA6, GDF9, GPC3, GUCA1B, GUCY2C, GUCY2F, GUCY2D, ONECUT1, HPGD, HES1, ILK, ING2, INHA, ITGA3, JUN, LTBP1, LTBP2, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, CITED1, SERPINE1, PTN, PTPRD, RBL1, RYR2, SOX11, SP1, ZEB1, KLF10, TTK, VIM, ZIC2, ZNF8, USP9X, USP9Y, ITGA8, CHRD, ADAM9, SLC33A1, NREP, CER1, ZFYVE9, ONECUT2, GDF15, ADAMTSL2, ZFYVE16, FSTL3, CITED2, RBM14, GIPC1, FERMT2, STRAP |
1572 | GO:0045321 | 0.00 | 2.09 | 31.60 | 47 | 86 | leukocyte activation | ABL2, BAX, ZFP36L2, BST2, RUNX2, CBFB, CCND3, CD7, CD8A, CD8B, TNFSF8, CD151, CDK6, CR2, CTPS1, CXADR, EP300, EPHB1, HHEX, ONECUT1, HPRT1, IGBP1, IMPDH1, IMPDH2, INS, ITGA4, ITGAD, ITGB1, SMAD3, NTRK1, P2RX7, RAG2, RPL22, SATB1, SELPLG, SRF, STK11, ADAM17, TPD52, WNT1, ZNF3, FZD5, FZD7, FZD8, FZD9, HDAC4, BTN3A1 |
1573 | GO:0051100 | 0.00 | 2.09 | 24.31 | 36 | 65 | negative regulation of binding | ADRB2, BAX, DAB2, DDIT3, GOLGA2, IFI16, IFIT1, IL10, ISL1, ITGA4, JUN, LRPAP1, P2RY1, PEX14, PLN, PRKCD, MAPK8, PEX19, RAP1GAP, SLN, SLPI, SOX11, SP100, AURKA, SUMO1, HMGA2, CAMK1, ADAM15, CPNE1, AURKB, ITGB1BP1, HAND1, EIF4A3, MAD2L2, CARM1, RUVBL2 |
1574 | GO:0055082 | 0.00 | 2.08 | 24.85 | 37 | 68 | cellular chemical homeostasis | ADRA2A, BAD, CRH, EFNA5, EPHA5, ERN1, GAS6, GATA4, GCG, GHRHR, GPLD1, GPR27, HMGCR, FOXA2, ICAM1, IGF1, IGF1R, IL1R1, KCNJ11, OXCT1, SERPINF1, PTGER4, PTPRN, PTPRN2, RAF1, RANBP2, SLC6A12, SMARCA4, SRF, STAR, VCAM1, OGT, HMGN3, NRXN1, C2CD2L, NR1H4, GJB6 |
1575 | GO:0051403 | 0.04 | 2.08 | 10.78 | 16 | 29 | stress-activated MAPK cascade | CAV3, CHUK, CREB1, ATF2, DUSP4, ELK1, HGF, IGBP1, JUN, PRDX1, PPP2R5D, RBM4, RPS6KA1, SKP1, NR2C2, CUL1 |
1576 | GO:0031328 | 0.00 | 2.08 | 46.91 | 70 | 131 | positive regulation of cellular biosynthetic process | ABCA1, ADM, ANXA1, APOA1, AVP, AVPR2, CALCR, CALM1, CALM3, CD3E, CD4, TNFRSF8, CDK4, CIRBP, CRH, DAZ1, DRD5, EDNRA, EEF2, EIF5A, ELAVL1, ACSL3, FGFR4, FSHR, GHRH, GHRHR, GLP1R, GNAL, GNAS, GPLD1, GUCA1A, GUCA1B, GUCA2A, GUCA2B, HRH1, HSPB1, HTR2C, IL12B, INSL3, NTRK2, NTSR1, P2RY11, PRKCD, PTAFR, PTGER4, PTHLH, RCVRN, RPS4X, RPS6KB1, RPS6KB2, CCL20, SNCA, SPN, VIP, VIPR2, WFS1, NSMAF, EIF2B5, RGN, AKAP12, GUCA1C, EIF4A3, CALCRL, RAMP2, PRG3, PEMT, CAP1, KHDRBS1, ARPP19, GLMN |
1577 | GO:0042752 | 0.02 | 2.08 | 14.19 | 21 | 38 | regulation of circadian rhythm | ARNTL, CHRM1, CREB1, CRY1, CRY2, CSNK1D, GNAQ, HNRNPD, PER1, PRKAA1, MAPK8, RBM4, SFPQ, SUV39H1, KLF10, TOP2A, UBE3A, SOX14, USP2, CLOCK, NR1D2 |
1578 | GO:2000113 | 0.02 | 2.08 | 12.75 | 19 | 35 | negative regulation of cellular macromolecule biosynthetic process | ACVRL1, ATR, BMPR2, BRCA2, HBEGF, DUSP1, HNRNPC, KCNK2, S100A11, TTF1, SMC1A, RGN, SMC3, TMEM59, ACOT8, ABCA7, CERS1, STAG2, CHEK2 |
1579 | GO:0065004 | 0.00 | 2.08 | 29.11 | 43 | 78 | protein-DNA complex assembly | ATRX, CENPA, CENPE, CENPF, CENPI, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, HIST1H1A, RB1, SET, SOX9, SOX12, TSPY1, CHAF1B, HIST1H4I, HIST1H2BG, HIST1H2BL, HIST1H2BN, HIST1H2BM, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, HAT1, RUVBL1, HIST1H3F, HIST1H2BJ, H1FX |
1580 | GO:0022600 | 0.02 | 2.08 | 14.20 | 21 | 38 | digestive system process | ACO1, ADRA2A, APOA1, CD36, COPA, CRH, DRD3, GHSR, HRH2, KCNQ1, OXTR, PAWR, SGK1, SLC22A5, SOX9, UCN, NR1H2, VIL1, TRPV1, SOAT2, STRAP |
1581 | GO:0002040 | 0.02 | 2.07 | 14.21 | 21 | 38 | sprouting angiogenesis | ACVRL1, ANGPT1, BMP4, CDC42, EGR3, PTK2B, FLT4, GPLD1, NR4A1, ITGA5, ITGB1, KDR, SRF, NRP1, SEMA5A, ITGB1BP1, KLF4, SLIT2, SEMA3E, RAMP2, ESM1 |
1582 | GO:0002708 | 0.02 | 2.07 | 14.21 | 21 | 38 | positive regulation of lymphocyte mediated immunity | C3, CD28, FCER1G, FCER2, HPX, IFNG, IL1B, IL12B, P2RX7, PRKCZ, PVR, XCL1, STAT5B, STAT6, TRAF2, TNFSF4, UNG, VAV1, WHSC1, FZD5, MALT1 |
1583 | GO:0050871 | 0.02 | 2.07 | 14.21 | 21 | 38 | positive regulation of B cell activation | BAD, BCL2, PRDM1, BTK, CD28, CD38, CD81, CDKN1A, CHRNB2, GPR183, IFNG, IL13, STAT5B, STAT6, TNFSF4, TNFRSF4, UNG, WHSC1, IKZF1, VAV3, TNFSF13B |
1584 | GO:0008016 | 0.03 | 2.07 | 11.47 | 17 | 31 | regulation of heart contraction | CACNA1B, CACNA2D1, CACNB3, CACNB4, HBEGF, GLP1R, KCND2, KCND3, KCNJ12, KCNJ14, KCNK3, S100A1, SP4, TNNT2, KCNK6, NUP155, CACNG2 |
1585 | GO:0009581 | 0.00 | 2.07 | 44.13 | 65 | 118 | detection of external stimulus | ABCA4, APOA1, ATP2B2, OPN1SW, CACNB4, CALM1, CALM3, CAV3, AKR1C4, CHRM1, CLPS, CNGA1, COL11A1, EPHB1, GPC4, FYN, OPN1MW, GPC3, GNAQ, GNAT1, GNAT2, GNB1, GNGT1, GNGT2, GUCA1A, GUCA1B, GUCY2F, GUCY2D, IGF1, KCNA1, KIT, NTRK1, NTSR1, PAWR, PDC, PDE6G, PRKCQ, RBP1, RBP2, OPN1LW, RCVRN, RGR, RPE65, RS1, SAG, SDC2, SDC4, SLC12A2, SOX2, TRPC3, TULP1, TRPV1, CSRP3, AKR1C3, TRPA1, SEMA5A, UNC119, SLC24A1, DHRS3, GUCA1C, SDC3, PIEZO1, NR2E3, GPC6, RRH |
1586 | GO:0010469 | 0.00 | 2.07 | 21.67 | 32 | 58 | regulation of receptor activity | ADRA2A, APLP2, APP, BICD1, CALM1, CALM3, CASQ2, CAV3, CFTR, STOM, EREG, GSTM2, HRC, IGF2, KCNJ1, P2RY1, SERPINE1, PDE4D, PLN, PRKCD, PRKCE, PSEN1, SHC1, ADAM17, BUD31, BAZ1B, GSTO1, AKAP6, KCNE2, HDAC6, TRDN, CACNG2 |
1587 | GO:0010721 | 0.03 | 2.07 | 11.47 | 17 | 31 | negative regulation of cell development | BCL2, CAV3, S1PR3, FBLN1, IGF1, LTF, TACSTD2, SMAD7, CITED1, SALL1, STAT1, TRPV1, PAX8, CTDP1, ITGB1BP1, MAD2L2, STRAP |
1588 | GO:0051129 | 0.00 | 2.07 | 31.78 | 47 | 86 | negative regulation of cellular component organization | ACVRL1, BIRC2, APOA1, CDC42, CLU, CLDN7, DAB2, ACE, DFFA, DNM2, DPP4, EIF4EBP1, FAP, FBLN1, FOXA2, DNAJB2, HSPA8, INS, KCNE1, SMAD6, SMAD7, CITED1, PEX14, PPM1A, PRKD1, PRKCZ, PTGER4, PTN, PEX5, RAC1, RAF1, SALL1, SDCBP, SLN, STAT1, TTC3, NR1H2, VDAC2, PICALM, OGT, NUMB, CFLAR, UNC119, ITGB1BP1, TMEM59, RAPGEF3, STRAP |
1589 | GO:1901700 | 0.00 | 2.07 | 27.19 | 41 | 79 | response to oxygen-containing compound | ACVR2B, ANGPT2, APOH, ATP5G3, BID, BRCA2, DAGLA, CD4, CD9, CHAT, COL6A2, ATF2, CTSH, CTSV, DBH, EPS8, ERCC1, GLUL, GOT2, GRN, GYS2, HLCS, IGFBP2, IHH, NTRK1, PAM, PFKFB2, ST6GAL1, SOX2, SP100, AURKA, NR2F2, TRPM2, UCN, PRDM2, SLC14A2, SLC10A3, MBD4, GPR55, SLC22A6, SETDB1 |
1590 | GO:0002758 | 0.00 | 2.07 | 60.59 | 89 | 162 | innate immune response-activating signal transduction | BIRC2, BIRC3, XIAP, BTK, CALM1, CALM3, CD86, CD36, CHUK, CREB1, ATF2, CTSK, CYBA, CYLD, DMBT1, DUSP4, ELK1, EP300, F2RL1, FCER1G, FYN, GFI1, HCK, ICAM2, ICAM3, IL1B, IRAK1, IRAK2, IRF1, ITGAM, ITPR1, ITPR2, JUN, KRAS, LTF, PIK3C3, PPP2R5D, PPP3R1, PRKACB, PRKACG, PRKCD, PRKCE, MAPK8, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, RAF1, RELB, RPS6KA1, SEC14L1, SKP1, TNFAIP3, HSP90B1, TYRO3, UBB, UBE2D2, CUL1, IKBKG, RIPK1, RIPK2, UBA3, PSMF1, PSMD6, TRIL, NR1H4, PSME3, PSMD14, TNIP1, CNPY3, MALT1 |
1591 | GO:2001233 | 0.00 | 2.07 | 38.65 | 57 | 104 | regulation of apoptotic signaling pathway | ACVR1, AVP, BDKRB2, BRCA1, CD44, CTH, CX3CR1, DBH, CTTN, EYA1, FGA, FGG, FYN, GCG, GPX1, GRINA, HGF, NRG1, HIF1A, HSPB1, ICAM1, IGBP1, IGF1, IL1A, IL1B, ING2, INS, ITGAV, OPA1, SERPINE1, PF4, PSEN1, PTPN1, RAF1, RPS6KB1, CX3CL1, SNAI1, SOD2, SP100, TNFAIP3, TPT1, TRAF1, VDAC2, WFS1, SCG2, URI1, NRP1, ARHGEF2, BAG5, RB1CC1, BCL2L10, FEM1B, TRAP1, PSME3, CREB3, IVNS1ABP, ZMYND11 |
1592 | GO:0010769 | 0.00 | 2.07 | 64.70 | 95 | 173 | regulation of cell morphogenesis involved in differentiation | ABL1, APOA1, ARHGAP4, BMPR2, CACNA1A, CDC42, CHN1, CHRNB2, COL1A1, DAB2, DCC, DNM2, EFNA1, EFNA5, CTTN, EPHA7, EPHB3, FBLN1, FGA, FGG, GDI1, GOLGA4, NRG1, FOXA2, IFRD1, ILK, LIMK1, TACSTD2, CAPRIN1, SMAD3, SMAD7, CITED1, NRCAM, NTRK2, NTRK3, OMG, RELN, PSEN1, PTEN, PTK2, PTPRD, RAC1, RAC3, RAP2A, RNF6, RREB1, S100A10, SALL1, SERPINB3, SDC2, SDCBP, SEMA3F, SGK1, ST6GAL1, SLIT3, SNAI1, SRF, STAT1, CDKL5, STK11, CNTN2, TNR, TTC3, TWIST1, PAX8, SEMA3B, RND2, RAB11A, NRP1, ARHGEF7, SEMA5A, ARHGEF1, NUMBL, ITGB1BP1, SLIT2, AATK, RAPGEF2, SEMA3E, IST1, CUL7, ARPC2, SEMA3A, BAIAP2, MAD2L2, STK25, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, OLFM4, TBR1, CIT, IL1RAPL1, STRAP |
1593 | GO:0008652 | 0.01 | 2.07 | 18.31 | 27 | 49 | cellular amino acid biosynthetic process | ABAT, AGXT, ASL, ASS1, BCAT1, CCBL1, CPS1, DHFR, DPYD, GAD1, GAMT, GATM, GLS, GLUD1, GLUL, GOT2, GPT, OAT, OTC, PAH, PSPH, PYCR1, ALDH18A1, SHMT1, SHMT2, SLC1A3, ALDH4A1 |
1594 | GO:0007566 | 0.04 | 2.07 | 10.85 | 16 | 29 | embryo implantation | ARHGDIB, BSG, EMP2, FBLN1, GRN, IL1B, ITGB4, PCSK5, PTGIS, RPL29, RXRA, SOD1, STC1, TRO, SCGB1A1, RECK |
1595 | GO:0036297 | 0.04 | 2.07 | 10.85 | 16 | 29 | interstrand cross-link repair | ATR, ERCC1, ERCC4, FANCA, FANCC, FANCD2, FANCE, FANCB, FANCF, FANCG, RAD51D, RPA2, RPA3, UBB, RNF8, DCLRE1A |
1596 | GO:0001503 | 0.00 | 2.06 | 31.20 | 46 | 84 | ossification | ACHE, ADAR, ATP6V1B1, BMP1, BMP3, BMP8B, CAT, CBFB, COL1A1, COL5A2, COL6A1, COL11A1, VCAN, CTGF, CTSK, CYP24A1, DHX9, EPHA2, ESR1, EXT1, EXT2, GPLD1, HNRNPC, IGF2, IGFBP3, IHH, INPPL1, PCP4, PENK, PEX7, MAPK8, PSMC2, PTHLH, RPL38, RPS11, RYR1, SORT1, SLC34A1, SNAI1, SP1, SPARC, STC1, DCHS1, DDX21, NR1I3, FSTL3 |
1597 | GO:0051047 | 0.00 | 2.06 | 75.09 | 110 | 201 | positive regulation of secretion | ABAT, ABL1, ABL2, ACHE, AGTR2, ALOX15B, ANG, ARF1, ATP6AP1, AVP, BAD, BLK, BMP6, CASP1, CASP5, CCK, CD38, CD58, CFTR, CHRNB2, CREB1, CRH, CSF1R, DRD3, EDN3, F2R, F2RL1, ACSL3, FCER1G, FGA, FGG, FGR, GALR1, GCG, GHRH, GHRHR, GLRA1, GLUD1, GLUL, GPLD1, GPR27, FFAR1, HIF1A, IFNG, IGF1, IL1A, IL1B, IL10, IL13, IL17A, INHA, INS, ISL1, KCNN4, KISS1, KNG1, NTSR1, OXCT1, OXTR, P2RX4, P2RX7, P2RY1, PAEP, PCP4, PFKFB2, SEPT5, PPID, PRKCQ, PRKCZ, PTAFR, RAB5A, RAB27A, RAB27B, S100A8, S100A9, SDC4, SDCBP, SLC18A1, SNCA, SOX11, STXBP1, SYT1, TAC1, TMF1, TRPM2, TSG101, TWIST1, TNFSF4, TNFRSF4, UCN, NR1H2, VEGFC, TRPV1, RAB7A, STAM, VAMP8, ADAM9, ARHGEF7, SYT7, IL1RL1, RAB9A, STXBP5L, RAB3D, GAB2, C2CD2L, PDCD6IP, TRIM16, SEC24A, CAPN10, GLMN |
1598 | GO:2000027 | 0.00 | 2.06 | 33.99 | 50 | 91 | regulation of organ morphogenesis | ABL1, ABL2, AGTR2, BAX, BCL2, BMPR1A, CAV3, RUNX2, CHAD, CNTF, DAB2, EDNRA, ESR1, ETV4, ETV5, EYA1, GPC4, FGF3, FZD2, B4GALT1, HGF, HOXC11, HOXD11, HES1, IFNG, RBPJ, ISL1, TACSTD2, CITED1, TNFRSF11B, PAX9, PTN, RAC1, RXRA, RYK, SALL1, SIX1, STAT1, TNFAIP3, TWIST1, WNT11, PAX8, FZD6, FZD7, NUMB, GPC6, SPRY1, CITED2, SEC24B, CARM1 |
1599 | GO:0043433 | 0.00 | 2.06 | 29.92 | 44 | 80 | negative regulation of sequence-specific DNA binding transcription factor activity | NR0B1, CAT, CDKN2A, CYLD, DDIT3, ESR1, GAS6, GFI1, FOXA2, PRMT2, IGF1R, IRAK1, IRAK2, SMAD7, PBX1, PEX14, PIM1, PTGIS, PTHLH, RB1, XCL1, SFRP4, SFRP5, SP100, TRIM21, TNFAIP3, TWIST1, TNFSF4, TNFRSF4, SUMO1, WFS1, FZD6, HDAC3, TAX1BP1, KLF4, HAND1, HDAC4, KEAP1, TRIB1, MAD2L2, SIVA1, RBCK1, ZNF234, WWP2 |
1600 | GO:0032101 | 0.00 | 2.06 | 76.95 | 113 | 209 | regulation of response to external stimulus | A2M, ACTL6A, ADAM10, AGTR1, AHSG, AKT2, ANXA1, XIAP, ATP6V0A1, BMP6, BMPR2, BNIP3, BNIP3L, C3, C7, CASP4, CASP5, CD6, CD36, CD59, CNR1, CSNK2A2, CTSK, CYBA, DCN, S1PR1, LPAR1, EDN3, EDNRA, CTTN, ERN1, F2R, F2RL1, F3, F7, PTK2B, FCER1G, FGF4, GAS6, KAT2A, FFAR3, CXCL1, CXCL3, HIF1A, FOXA2, HSPB1, IL1B, IL1R1, IL17A, IL18, IDO1, KDR, CD180, CD46, NTF3, NTRK3, OMG, PAFAH1B2, PARK2, PER1, PF4, PF4V1, CFP, PGC, PIP4K2A, PRKD1, PSMA6, RAC2, S100A7, S100A8, S100A9, S100A12, CCL21, CCL24, CXCL6, CXCL5, XCL1, CX3CL1, SELE, SELP, SREBF1, STAT5B, XCL2, TAC1, ADAM17, TNFSF4, U2AF1, SCGB1A1, VEGFB, VEGFC, ZBTB17, FZD5, SCG2, RAB7A, EPM2A, RUVBL1, VAMP8, BECN1, TNFSF14, TRIM24, TNFSF18, USP14, IL1RL1, RAB33A, ATG5, CXCL14, CLOCK, NR1D2, HDAC6, TRIM13, TNIP1, ATG7, TBR1 |
1601 | GO:0006818 | 0.00 | 2.06 | 38.15 | 56 | 102 | hydrogen transport | ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP1A4, ATP4A, ATP4B, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, ATP5O, COX4I1, COX5B, COX6A1, COX6B1, COX7A1, COX7C, COX8A, COX15, CYB5A, DRD3, IL13, SLC11A2, SLC9A1, SLC9A2, SLC9A3, SLC9A5, SLC15A1, SLC15A2, TWIST1, UCP1, UQCRC1, UQCRH, ATP6V0D1, COX7A2L, SLC33A1, SLC9A3R1, ATP6V1G1, ATP5J2, RAPGEF3, ATP5H, SLC9A6, SLC35A1, ATP5L, UQCR11 |
1602 | GO:0034644 | 0.02 | 2.05 | 14.96 | 22 | 40 | cellular response to UV | ATF4, ATR, BAX, CASP9, CDC25A, CDKN1A, CHEK1, DDB2, EIF2S1, EP300, ERCC4, PCNA, PPID, PTN, STK11, TP73, XPC, YY1, TP63, AURKB, CERS1, RUVBL2 |
1603 | GO:0006928 | 0.00 | 2.05 | 247.31 | 357 | 681 | movement of cell or subcellular component | ACTB, ACTG1, ADCY3, AGTR1, ANG, APOA1, APP, ARAF, ARF6, ASCL1, ASTN1, RERE, ATOH1, ATP1A4, ATP1B3, KIF1A, AXL, BAX, BICD1, DST, BSG, BTG1, TSPO, CACNB3, CACNB4, CALM1, CALM3, CAMK2A, CAPZA1, CAPZB, CAV3, CCK, CD9, CD44, CD58, CD72, ADGRE5, CD151, CDC42, CENPE, CHN1, AP2S1, CLTA, CCR5, LTB4R, COL4A3, COL4A5, COL5A2, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF2RB, CSNK2A1, CSNK2A2, VCAN, CSPG4, CTGF, CTNNA2, CXADR, DBH, DCC, DCX, DLG3, DLX5, DNM1, DNAH5, DNAH8, DYNC1H1, DYNC1I1, DYNC1I2, DPP4, DUSP5, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EGR3, CTTN, EMX2, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPS8, ERBB2, EREG, ERG, ETV4, EXT1, F2, FAP, FCER1G, FGF3, FGF5, FGFR3, FGFR4, FPR1, FPR3, FUT8, FYN, BLOC1S1, GFRA1, GPM6A, GPR15, GPX1, GRB2, GRIN2A, ARHGAP35, HIST1H1T, HCK, HEXB, NR4A1, HRH1, HES1, HSPA8, HSP90AA1, HSP90AB1, IL2RA, IL10, IL12B, IL13, ING2, ISL1, ITGA1, ITGA9, ITGAM, ITGAX, ITGB4, KCNE1, KCNH2, KCNQ1, KIF5A, KLC1, KIF25, KRAS, KRT2, LDHC, ABLIM1, LIMK1, MARK3, SMCP, MYO1B, NRCAM, NRTN, NTRK1, NTRK2, NTN3, OGDH, OLR1, OPA1, OR1D2, OTX2, P2RY1, PEBP1, PALM, PAX3, PCM1, PEX7, PEX13, PEX14, SERPINB5, SERPINI2, PIK3C2B, PIK3CB, PPP5C, PRKCD, PRKCI, PRKCQ, PRKCZ, PSPN, PROC, PSEN1, PSG2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PYY, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTPN6, PTPRA, RAB1A, RAB6A, RAB13, RASA2, RFX3, RPGR, RPL24, RPS6KA1, RYK, S100A2, S100A8, S100A9, S100A12, SAA4, SCN4B, SCNN1B, CCL22, SDC2, SELL, SELPLG, SFTPD, SHC1, SIAH1, SIX1, SIX3, SLC9A1, SLC16A1, SLIT3, FSCN1, SOD1, SORD, SOS1, SOS2, SOX1, SOX10, SPN, SPOCK1, SRMS, CDKL5, XCL2, CNTN2, NR2F1, TMF1, TMOD1, TNNC2, TNNI2, TNNI3, TNNT1, TNP2, TNR, TOP2B, TPM2, TRPC1, TRPC3, TRPC4, TRPC5, TYRO3, TYROBP, UBB, CLRN1, VAV1, VCAM1, VIM, DNALI1, SCG2, ARHGEF5, FGF23, SLC7A5, USP9X, USP9Y, EPX, UXT, CUL3, FOXN1, SORBS2, CNTNAP1, DGKZ, AP3B1, KLF7, DNAH17, SSNA1, DCHS1, DYNLL1, PEA15, VNN2, PHOX2B, WASF1, AP3D1, RPS6KA4, KALRN, DOK2, TAOK2, CER1, NRXN3, KIF3B, NRXN1, PSMF1, NRG2, CDC42BPB, NUP155, FEZ2, SDC3, IFT140, DLGAP5, ARHGEF11, ZEB2, ELMO1, GAB2, FARP2, KIAA0319, PSMD6, RBX1, KCNE2, ABI1, RANBP9, GPC6, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN1, ARPC2, KIF20A, AKAP9, ABI2, RASA4, WASF2, CHST4, TNK2, PSME3, PSMD14, APC2, KATNB1, SPON2, VAV3, CAP1, PROCR, ARPC1A, DPYSL4, KIF1C, CHL1, GIPC1, FRS3, AP3M2, KIF2C, IFT27, VAX1, KIF3A, KPTN, SLC7A9, BVES |
1604 | GO:0070887 | 0.00 | 2.05 | 26.37 | 40 | 80 | cellular response to chemical stimulus | ACY1, ADH1B, ADH5, AHCY, ALDH1A1, ALDH2, ALDH3A1, AOC2, COMT, CRYZ, CYP2A6, CYP2A13, CYP2F1, CYP3A4, CYP8B1, CYP51A1, ESD, FDXR, GSTM1, GSTZ1, MAT2A, PCP4, PTGS1, RYK, SCN3A, SULT1E1, SULT1A1, SULT1C2, SULT2B1, TPMT, UGDH, UGP2, UGT2B4, CES2, PAPSS2, PAPSS1, GSTO1, GLYAT, AKR1A1, SLC26A1 |
1605 | GO:1902591 | 0.01 | 2.05 | 19.07 | 28 | 51 | single-organism membrane budding | ARCN1, AREG, ARF1, CD59, COPA, CSNK1D, CTSZ, GOLGA2, GRIA1, INSIG1, LMAN1, PPP6C, PRKCI, RAB1A, TRAPPC2, TRAPPC10, CUL3, USO1, VAPB, COPB2, SEC22B, GOSR2, PREB, ATP8A1, SEC24B, SEC23A, SEC24A, TMED2 |
1606 | GO:0034329 | 0.00 | 2.04 | 27.93 | 41 | 75 | cell junction assembly | ACTB, ACTG1, ANG, ARL2, CD9, CDH1, CDH3, CDH6, CDH7, CDH8, CDH9, CDH10, CDH12, CDH15, CDH17, CLDN3, CTNNA1, ACE, FLNC, GJA4, GJA5, GJB1, RAPGEF1, ILK, ITGB1, LIM2, PRKCI, PVR, RAB13, RSU1, SNAI1, FSCN1, SRF, STRN, WNT11, FZD5, CNTNAP1, CLDN12, CLDN1, ARHGEF6, RAPGEF2 |
1607 | GO:0048634 | 0.04 | 2.04 | 11.57 | 17 | 31 | regulation of muscle organ development | CAV3, CENPF, CXADR, DDX5, TSC22D3, FGF3, KCNK2, SMAD3, S100B, SIX1, TP73, TWIST1, HDAC3, CTDP1, HDAC4, NR1D2, USP19 |
1608 | GO:0090287 | 0.00 | 2.04 | 23.85 | 35 | 64 | regulation of cellular response to growth factor stimulus | AGTR2, CAV2, CAV3, RUNX2, CD63, DAB2, DCN, DNM2, FGF4, ONECUT1, HRG, ING2, LTBP1, SMAD3, CITED1, OTX2, SDCBP, STK11, ADAM17, ZEB1, UBB, ITGA8, NREP, SLIT2, ZFYVE9, ONECUT2, ADAMTS3, ADAMTSL2, FGFBP1, SPRY1, CITED2, SLC9A6, CXCL13, GIPC1, STRAP |
1609 | GO:0009132 | 0.00 | 2.04 | 23.19 | 34 | 62 | nucleoside diphosphate metabolic process | AK1, AK2, AK4, ALDOB, ALDOC, ARNT, BAD, ENTPD2, DLG2, DLG3, DTYMK, ENO2, ENO3, GAPDH, GPD1, HIF1A, IGF1, INS, LDHA, OGDH, P2RX7, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PGM1, PPP2R5D, PRKAA1, PRKAG1, RRM2, STAT3, OGT, HDAC4 |
1610 | GO:0042472 | 0.00 | 2.04 | 23.19 | 34 | 62 | inner ear morphogenesis | ALDH1A3, ATOH1, ATP2B2, ATP6V1B1, BCR, COL11A1, DLX5, DLX6, EPHB2, EYA1, FGF3, FZD2, GFI1, HMX2, INSIG1, OTX1, OTX2, PRRX1, RAC1, SIX1, SOD1, SOX2, SOX9, ZEB1, CLRN1, WNT1, ZIC1, PAX8, FZD6, ITGA8, HESX1, NRP1, SLC9A3R1, SEC24B |
1611 | GO:0006979 | 0.01 | 2.04 | 16.98 | 25 | 46 | response to oxidative stress | ALAD, APP, BTG1, CD38, CHUK, DHCR24, ERCC1, ERCC3, IDH1, KRT1, OGG1, PSEN1, PSMB5, PTGS1, TAT, UCN, XPA, PXDN, EPX, ATRN, PDLIM1, OXSR1, SGK2, RCAN2, PSIP1 |
1612 | GO:0045931 | 0.02 | 2.04 | 15.67 | 23 | 42 | positive regulation of mitotic cell cycle | ABL1, ANXA1, APP, CCND1, BRCA2, CCNB1, CDK4, EIF4E, EIF4EBP1, HES1, PBX1, RAD51C, RAD51B, RDX, RPS6KB1, SMARCD3, STAT5B, TAL1, UBE2E2, CUL4A, RAB11A, PHOX2B, USP2 |
1613 | GO:0031334 | 0.00 | 2.04 | 36.21 | 53 | 97 | positive regulation of protein complex assembly | ARF1, ARF6, ARL2, BAX, BID, CAV3, CCK, CD36, CDH17, CTTN, PTK2B, GRB2, HCK, ICAM1, IDE, PFN1, PFN2, PRKCE, MAPK8, RAC1, RGS2, RPS3, CLIP1, CCL21, CCL24, FSCN1, TAL1, SUMO1, VIL1, ARHGEF5, HRK, WASF1, PICK1, BAG4, PIEZO1, HDAC6, BCL2L11, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, ABI2, TUBGCP3, CDC42EP2, BAIAP2, ARPC1A, CXCL13, CDC42EP3, TUBGCP2, TPPP, CORO1A |
1614 | GO:0000245 | 0.04 | 2.04 | 11.59 | 17 | 31 | spliceosomal complex assembly | DDX1, SRSF1, SRSF5, SRSF6, SFSWAP, SNRPC, SNRPD1, SNRPD2, SNRPE, SRPK2, SRSF9, SCAF11, DDX23, USP39, TXNL4A, SF3A3, PSIP1 |
1615 | GO:0017158 | 0.04 | 2.04 | 11.59 | 17 | 31 | regulation of calcium ion-dependent exocytosis | ADRA2A, ARF1, CACNA1A, B4GALT1, GLRA1, PFN2, SEPT5, RAB5A, REST, SPINK1, STXBP1, STXBP3, SYN1, SYT1, SYT4, DOC2A, SYT7 |
1616 | GO:0030517 | 0.04 | 2.04 | 11.59 | 17 | 31 | negative regulation of axon extension | ARHGAP4, IFRD1, RNF6, SEMA3F, TNR, SEMA3B, NRP1, SEMA5A, SLIT2, AATK, SEMA3E, SEMA3A, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B |
1617 | GO:1901796 | 0.04 | 2.04 | 11.59 | 17 | 31 | regulation of signal transduction by p53 class mediator | ATM, ATR, BDKRB2, CD44, CDKN2A, DDX5, DYRK1A, HIC1, ING2, PARK2, SNAI1, TP73, TWIST1, UBB, TRIM24, EEF1E1, HEXIM1 |
1618 | GO:0046165 | 0.00 | 2.04 | 28.01 | 41 | 75 | alcohol biosynthetic process | ACHE, ACLY, APOA1, CFTR, CHAT, CHKB, CYP3A4, CYP11B1, CYP51A1, DHCR7, DHCR24, CYB5R3, DPAGT1, PTK2B, FDFT1, FDPS, FGF7, GFI1, GOT1, HMGCR, HMGCS1, HMGCS2, IMPA1, INSIG1, LCAT, PCK1, PCYT1A, REST, SNAI1, SOD1, STAR, CNBP, AKR1C3, CH25H, CEPT1, PEMT, ACAA2, ERLIN1, EBP, ERLIN2, C14orf1 |
1619 | GO:0030182 | 0.01 | 2.03 | 17.57 | 26 | 49 | neuron differentiation | BYSL, RUNX2, DAPK3, DNMT1, S1PR1, EDN3, EMX2, ERCC3, EYA1, PTPRR, SIX1, SMARCA1, STAT3, WNT11, WNT2B, FZD5, FZD4, FZD7, FZD8, ALDH1A2, AIFM1, COPS2, SNPH, IKZF1, SPINK5, FZD10 |
1620 | GO:0034142 | 0.01 | 2.03 | 19.82 | 29 | 53 | toll-like receptor 4 signaling pathway | BIRC2, BIRC3, BTK, CD36, CHUK, CREB1, ATF2, DUSP4, ELK1, F2RL1, IRAK1, IRAK2, ITGAM, JUN, LTF, PPP2R5D, PRKCE, MAPK8, RPS6KA1, SKP1, TNFAIP3, UBB, UBE2D2, CUL1, IKBKG, RIPK1, RIPK2, TRIL, NR1H4 |
1621 | GO:0042035 | 0.01 | 2.03 | 19.82 | 29 | 53 | regulation of cytokine biosynthetic process | BCL3, CD3E, CD4, CD28, CD80, CD86, TNFRSF8, EREG, GHSR, HSPB1, IFNG, IL1A, IL1B, IL10, IL12B, INHA, IRF1, PRG2, PRKCQ, PTAFR, CCL20, SFTPD, SPN, STAT5B, KLF4, PRG4, PRG3, IGF2BP3, GLMN |
1622 | GO:0010565 | 0.01 | 2.03 | 20.49 | 30 | 55 | regulation of cellular ketone metabolic process | ACACB, ACADL, ACADVL, AKT2, ANXA1, APOA1, AVP, BMP6, BRCA1, CNR1, FGFR4, GCG, KAT2A, GHSR, INSIG1, PDK4, PRKCE, REST, SNCA, SREBF1, STK11, TWIST1, NR1H2, PDHX, AKR1C3, KAT2B, RGN, EIF2AK3, ERLIN1, ERLIN2 |
1623 | GO:0060560 | 0.03 | 2.03 | 12.29 | 18 | 33 | developmental growth involved in morphogenesis | APP, AREG, BMP4, DCC, S1PR1, EFNA5, EPHA7, ESR1, OMG, PTHLH, SALL1, SIX1, SLC12A2, SOX9, WNT11, RND2, IST1, SPRY1 |
1624 | GO:0045333 | 0.03 | 2.02 | 12.30 | 18 | 33 | cellular respiration | ACO1, ACO2, ADSL, BAX, BNIP3, CAT, BLOC1S1, HIF1A, IDH1, IDH3A, MDH1, MDH2, OGDH, UCN, SUCLG2, SUCLG1, SUCLA2, TRAP1 |
1625 | GO:0051169 | 0.00 | 2.02 | 93.13 | 135 | 249 | nuclear transport | ADAR, AGTR2, ANGPT1, ARNTL, RERE, BARD1, BCL3, BMP4, BMP6, BMPR1A, BRCA1, CAMK4, CBLB, CD36, CDH1, CDKN1A, CDKN2A, CSE1L, CYLD, DAB2, EDA, EGR2, EIF4E, EIF5A, F2R, FYB, GAS6, GLE1, GNAQ, SFN, HCLS1, HHEX, AGFG1, HES1, HSPA9, HSP90AB1, IFNG, IGF1, IL1B, IL10, IL12B, IL18, JUN, KPNA1, KPNA2, KPNA3, KPNA4, KPNA5, TNPO1, IPO5, SMAD3, CITED1, PPP1R12A, TONSL, NUP88, NUP98, OGG1, OR1D2, PRDX1, PPM1A, PPM1B, PPP3R1, PRKCD, PRKCQ, RAN, RANBP2, RANGAP1, RBM4, UPF1, RPS28, SET, SFRP5, SRSF1, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SIX3, SLC9A1, SLC11A1, SP100, STAT3, STYX, DYNLT1, TRIP6, TSC1, TSC2, U2AF1, ZIC1, NUP214, AAAS, ANP32A, AKAP1, FZD7, DYRK2, CAMK1, RGS20, AKR1C3, SRSF9, TNFSF14, INPP4B, HDAC3, SEMA5A, RPL23, SLC9A3R1, ZFYVE9, AKAP6, LITAF, NUP155, IPO13, NUP93, KEAP1, ZC3H11A, SMG7, RBM8A, NUTF2, DDX39A, APC2, RAPGEF3, TACC3, NXF1, CREB3, CHERP, RBCK1, TXNIP, KHDRBS1, AHCYL1, MALT1, EDAR, RNPS1, SEC61B, NUPL2, NUDT4, AKAP13 |
1626 | GO:0032535 | 0.00 | 2.02 | 73.68 | 107 | 197 | regulation of cellular component size | ABL1, ADD1, ANXA7, ARF1, ARF6, ARHGAP4, ATP2B2, BBS4, BMPR2, CAPG, CAPZA1, CAPZB, CAV3, CDK4, CFL2, CLCN3, CLCN6, CLNS1A, CREB1, DCC, DNM2, E2F4, EFNA5, CTTN, EPHA7, EPS8, F2RL1, PTK2B, GOLGA4, GRB2, HCK, HCLS1, NRG1, HIF1A, HSP90AB1, ICAM1, IFRD1, ILK, KCNN4, LIMK1, NRCAM, NTRK3, OMG, P2RX7, PFN1, PFN2, PRKCD, PRKCE, PTEN, RAB3B, RAB5A, RAC1, RDX, RNF6, CCL21, CCL24, SEMA3F, SLC6A12, SRF, CDKL5, CNTN2, TMOD1, TNR, TP73, TSC1, UCN, VAV1, VIL1, SEMA3B, RND2, OGT, RAB11A, PEX11A, NRP1, WASF1, SEMA5A, LATS1, SLIT2, SLC9A3R1, PICK1, BAG4, AATK, SEMA3E, IST1, RB1CC1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, ABI2, SEMA3A, RAPGEF3, CDC42EP2, VAV3, BAIAP2, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, ARPC1A, ARFGEF1, CDC42EP3, AVIL, CORO1A |
1627 | GO:0000278 | 0.01 | 2.02 | 19.77 | 29 | 54 | mitotic cell cycle | CDC5L, DYRK1A, E2F2, FEN1, CENPI, RAB1A, RANGAP1, RBL1, RBL2, RFC3, RFC4, RFC5, RPS27, RRM1, SET, XRCC2, HIST1H4I, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, BLZF1, USO1, UBA3, USP3, PRDM5 |
1628 | GO:0007015 | 0.00 | 2.02 | 70.31 | 102 | 188 | actin filament organization | ABL1, ABL2, ACTN1, ADD1, ANG, APOA1, ARF1, ARF6, ARHGAP6, BBS4, BCL2, CAPG, CAPZA1, CAPZB, CAV3, CDC42, CFL2, CTGF, CTNNA1, DIAPH1, DIAPH2, DPYSL3, S1PR1, LPAR1, EMP2, CTTN, EPHA1, EPS8, F2RL1, PTK2B, GHSR, GRB2, HCK, HCLS1, ICAM1, INPPL1, LIMK1, TACSTD2, SMAD3, MYO1B, PARK2, PAWR, PFN1, PFN2, PRKCD, PRKCE, PRKCI, PRKCQ, PTGER4, RAC1, RAC2, RDX, S100A10, CCL21, CCL24, SDC4, SLC9A1, FSCN1, SRF, TAC1, TMOD1, TNNT2, HSP90B1, TSC1, CLRN1, VIL1, WNT11, ALMS1, ARHGEF5, CUL3, SORBS2, GAS7, WASF1, SEMA5A, LATS1, ARHGEF2, ITGB1BP1, SLIT2, PICK1, BAG4, BCAR1, ABI1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, ABI2, WASF2, SORBS3, RAPGEF3, CDC42EP2, BAIAP2, MAD2L2, ARPC1A, ARFGEF1, SORBS1, CDC42EP3, AVIL, KPTN, CORO1A |
1629 | GO:0002292 | 0.03 | 2.01 | 12.34 | 18 | 33 | T cell differentiation involved in immune response | ANXA1, BCL3, CD80, CD86, FCER1G, HLX, IFNG, IL12B, CD46, PRKCZ, PTGER4, RARA, RELB, STAT6, TSC1, TNFSF4, RIPK2, TNFSF18 |
1630 | GO:0015833 | 0.02 | 2.01 | 13.67 | 20 | 37 | peptide transport | ABCA1, ACVR2B, ANXA1, CDH17, EDN3, IL1RN, PTPRN, PTPRN2, RAB1A, RAF1, SLC15A1, SLC15A2, STXBP3, HNF1A, VIP, TRPV1, SLC9A3R1, EIF2AK3, RIMS2, CPLX1 |
1631 | GO:0060041 | 0.00 | 2.01 | 25.41 | 37 | 68 | retina development in camera-type eye | ACHE, ACTL6A, ATP2B1, BAX, BMP4, CRX, GNAT1, GNAT2, GNB1, GPM6A, IHH, IMPDH1, IMPDH2, NTRK2, PAX4, SERPINF1, PSEN1, PTN, PTPRM, RARB, PRPH2, RPGR, RPE65, RPL24, RRM1, RS1, SIX3, SMARCA4, SMARCD3, SOX2, SOX9, TUB, TULP1, IFT140, NR2E3, IRX5, IKZF1 |
1632 | GO:0048705 | 0.01 | 2.01 | 21.27 | 31 | 57 | skeletal system morphogenesis | ACVR2B, BMP1, BMP6, BMPR2, SERPINH1, CDX1, CHAD, COL1A1, COL9A1, COMP, CTGF, DLX5, FGF4, FGFR3, HOXD8, IDUA, INPPL1, INSIG1, LTF, P2RX7, PEX7, PSEN1, PTHLH, RARA, RARB, SOX9, STC1, DHRS3, CER1, IFT140, CARM1 |
1633 | GO:0007507 | 0.00 | 2.01 | 55.03 | 80 | 148 | heart development | ACACB, ACVR2B, ADM, ADRA1B, APLNR, ATM, BBS4, COL3A1, ATF2, CRKL, VCAN, DNAH5, DNM2, EDNRA, EP300, ERBB2, EYA1, FBN1, FZD2, GAA, GPC3, GNAQ, HHEX, HIF1A, IHH, ILK, ITGA3, ITGA4, JUN, KCNJ8, LTBP1, SMAD3, NTRK3, OXCT1, OXTR, PAM, PAX3, PCNA, PCSK5, PSEN1, PSKH1, PTK2, PTN, PTPRJ, RAF1, RYR1, SALL1, SCN5A, SHC1, STIL, SIX1, SMARCD3, SNAI1, SOX11, SPARC, TSC2, KDM6A, VCAM1, VEGFB, WHSC1, WNT11, KCNAB1, ADAM19, ADAM15, CDKL1, NRP1, BAZ1B, DHRS3, TRIP11, ADAMTS1, IFT140, SNX17, RB1CC1, COX17, COL4A3BP, CALCRL, RAMP2, CITED2, SEC24B, HEXIM1 |
1634 | GO:0022008 | 0.00 | 2.01 | 242.81 | 347 | 662 | neurogenesis | ABL1, ACTB, ACTG1, ADAM10, ADM, AKT2, ALK, ANGPT1, ANXA1, APOA1, ARAF, AREG, PHOX2A, ARNTL, ASTN1, RERE, ATP2B2, AXL, ADGRB1, BAX, BBS4, BCHE, PRDM1, BOK, BYSL, DAGLA, CACNA1A, CACNB3, CACNB4, CALM1, CALM3, CALU, CAMK2A, RUNX2, CCK, CD9, CD72, CDC20, CDC42, CDH1, CDK6, CHN1, CHRNB2, AP2S1, CLU, CLN5, CLTA, CNP, COL4A3, COL4A5, COL5A2, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2RB, CSNK2A1, CSNK2A2, VCAN, CSPG4, CTF1, CTNNA2, CTNND2, DAPK3, DCX, DFNA5, DHFR, DLG3, DLX5, DNM1, DNM2, DNMT1, EPYC, HBEGF, ECM2, DUSP5, S1PR1, EDN3, EEF2, EFNA3, EFNA4, EFNB1, EGR2, EIF2B1, EPHA2, EML1, EMX1, CTTN, EMX2, EN1, EPHA1, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, ERBB2, EREG, ERCC3, ETV4, EVX1, EXT1, EYA1, FABP7, ACSL4, FGF3, FGF4, FGF5, FGF7, FGFR4, FZD2, GABRA5, GAS6, BLOC1S1, GFRA1, GNAQ, GNAT1, GNAT2, GNGT1, GPM6A, GRB2, GRID2, GRIN2A, HEXB, HMBS, HOXC10, HOXD9, HOXD10, HPRT1, HSPA8, HSP90AA1, HSP90AB1, IGF1, RBPJ, IHH, IL2RA, ITGA1, ITGA5, ITGA9, ITGAV, JUN, KCNA1, KCNJ10, KIF5A, KRAS, ABLIM1, LLGL2, MAP6, MARK3, KITLG, SEPT2, SLC11A2, NRL, NRTN, NTF4, NTN3, OGDH, OGN, OMP, OPCML, OTX2, P2RY1, PEBP1, PAX3, PENK, PEX7, PEX13, ATP8B1, PRRX1, PPP5C, PRKCQ, PRKCZ, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTPRA, PTPRJ, PTPRM, PTPRR, RAB13, RAC1, RAC2, RAC3, RAF1, RAP2A, RASA2, RB1, RPGR, RPE65, RPL24, RPS6KA1, RXRA, RYK, S100A6, S100A8, S100A9, S100B, SCN5A, SDC2, SDC4, SDCBP, SHC1, SIAH1, SIX1, SLC1A3, SLC8A3, SLIT3, SMARCA1, SMARCC2, SMARCE1, SNAP25, SOD1, SOS1, SOS2, SOX1, SPAST, AURKA, STRN, STXBP1, TACC1, TAL1, TBCE, NR2F1, NR2F2, TOP2B, TRPC1, TRPC3, TRPC4, TRPC5, TULP1, TULP3, TWIST1, TYROBP, UBB, UCN, USH2A, CLRN1, VTN, WEE1, WNT1, WNT11, WNT2B, ZNF217, FZD5, FGF23, USP9X, PICALM, FZD4, FZD7, FZD8, FZD9, SOX14, CUL3, CNTNAP1, GAS7, KLF7, UNC5C, DCHS1, BECN1, PEA15, NRP2, ALDH1A2, ARHGEF7, EIF2B3, EIF2B2, EIF2B5, RPS6KA4, KALRN, AIFM1, KLF4, NREP, COPS2, SLC9A3R1, NRXN3, NRXN1, PICK1, CHST3, ONECUT2, PSMF1, SLC4A7, NRG2, FEZ2, IFT140, SNPH, ARHGEF11, FARP2, PSMD6, RBX1, NR2E3, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN2, ARPC2, AKAP9, RASA4, FARP1, PSME3, PSMD14, IRX5, IKZF1, SPON2, SEC24B, VAV3, TACC3, SLC9A6, CAP1, ATG7, ARPC1A, ARFGEF1, DPYSL4, TACC2, TBR1, CHL1, FRS3, RAB10, AFG3L2, SPINK5, RAB35, FZD10 |
1635 | GO:0001525 | 0.00 | 2.01 | 32.93 | 48 | 89 | angiogenesis | AAMP, ACVR1, JAG1, ANG, BAX, KLF5, COL15A1, CSPG4, CTGF, TYMP, S1PR1, EDNRA, EPHB1, EPHB2, EPHB3, EREG, FAP, GJA5, RBPJ, IHH, IL18, ITGAV, JUN, LAMA5, MEOX2, NRCAM, PRKX, PTEN, PTK2, S100A7, SHB, SHC1, SRPK2, TAL1, VEZF1, FZD5, SCG2, FZD8, ADAM15, NRP2, NRXN3, NRXN1, HAND1, EIF2AK3, SLC12A6, WASF2, CALCRL, VAV3 |
1636 | GO:0009124 | 0.01 | 2.00 | 21.32 | 31 | 57 | nucleoside monophosphate biosynthetic process | ADSL, ADSS, AK1, AK2, AK4, AMPD1, AMPD2, APRT, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, ATP5O, DUT, HPRT1, IMPDH1, IMPDH2, LDHC, PFAS, SHMT1, STAT3, TYMS, UPP1, ATP5J2, SLC25A13, ATP5H, ATP5L |
1637 | GO:0034111 | 0.01 | 2.00 | 21.32 | 31 | 57 | negative regulation of homotypic cell-cell adhesion | ABAT, ADRB2, ALOX12, ANXA1, BMP4, CBLB, CDKN2A, CTLA4, CYLD, ERBB2, HLX, IFNA2, IHH, IL2RA, IL10, IDO1, IRF1, PAWR, PRKAR1A, PRKCD, PTPN6, RDX, XCL1, SFTPD, SPN, TNFSF4, SCGB1A1, PDE5A, TNFSF18, SOCS6, GLMN |
1638 | GO:0007517 | 0.00 | 2.00 | 45.46 | 66 | 122 | muscle organ development | ACHE, AEBP1, ASS1, KLF5, CASQ1, CAV2, CHD2, CNTF, COL3A1, COL6A3, COL11A1, CSF1R, CTF1, DCN, DSP, HBEGF, S1PR1, EEF2, EGR2, EGR3, EP300, EVC, FZD2, GPX1, HLF, HLX, HOXD9, HOXD10, IGF1, IGFBP5, ISL1, LAMA5, SMAD7, MEOX2, FOXO4, PAX3, RB1, RXRA, RYR1, RYR2, SCN8A, SGCA, SGCB, SMTN, SOX11, SVIL, TAGLN, TAZ, NR2F2, TNNC1, TNNI3, TNNT2, KCNAB1, CSRP3, SAP30, CFLAR, SGCE, PHOX2B, COPS2, GTF3C5, HAND1, SPEG, HMG20B, VAMP5, VAX1, BVES |
1639 | GO:0008203 | 0.03 | 2.00 | 13.05 | 19 | 35 | cholesterol metabolic process | ABCA1, ACADL, ACADVL, APLP2, APP, CAT, CYP11B1, FDXR, LCAT, LIPC, LIPE, RXRA, STAR, TNFSF4, CUBN, SOAT2, CH25H, SNX17, NR1H4 |
1640 | GO:0050790 | 0.00 | 2.00 | 126.20 | 183 | 351 | regulation of catalytic activity | ACVR2B, ALK, ANGPT1, ARAF, TRIM23, ARF1, AVPR2, CCND1, BCL2, CALCR, CAMK2A, KRIT1, CCNC, CCND3, CCNE1, CCNG1, CCNH, CCNT1, CCNT2, CD4, CD81, CDC25A, CDC25C, CDC42, CDK2, CDK4, CENPE, CKS1B, CKS2, CLU, CLPS, CRKL, CSF1R, CSF2RB, CSPG4, ACE, DKC1, RCAN1, HBEGF, EDN3, EEF1A2, EFNA1, EMP2, EPHA8, EREG, ERCC6, ACSL1, FGF3, FGF4, FGF5, FGF7, FGFR4, FGR, FLT3, FPR1, FSHR, FYN, GCG, GHRHR, GLP1R, GNAL, GNG3, GRB2, GRIN2A, GRM1, CXCL1, GTF2F1, GUCA1A, GUCA1B, GUCA2A, GUCA2B, NRG1, HSPB2, HSP90AB1, IGF2, IGFBP3, IL2RA, IL12B, IRAK1, IRAK2, MARK3, KITLG, MAP3K11, PPP1R12B, SEPT2, NVL, P2RX7, P2RY11, PFKFB1, PFKFB2, PIK3CB, PIM1, FXYD3, PPP5C, PRKAA1, PRKAG1, PRKCQ, RELN, PSAP, PTPRA, RAC1, RAC2, RAP2B, RBL1, RBL2, RCVRN, S100A12, SDC4, SFTPB, SGK1, SHC1, STIL, SLC11A1, STK10, STK11, ADAM17, TPD52L1, TSG101, TNFRSF4, UCN, UVRAG, VIP, VIPR2, WFS1, ZNF16, FZD5, SHOC2, FZD4, FZD8, NSMAF, OGT, PIK3R3, IKBKG, IKBKAP, CAMK1, MAPKAPK5, PDE5A, DYNLL1, BECN1, PEA15, ADAM9, RIPK2, DPM2, DIRAS3, UNC119, CCNE2, AURKB, S1PR2, GTF3C4, TAOK2, SLC9A3R1, BAG3, NRG2, TRAF4, GUCA1C, SLK, ATG13, ZEB2, EPM2AIP1, OXSR1, RBX1, ABI1, TOM1L1, UBA2, SAE1, RAD50, FEM1B, AKAP9, RCAN2, ZER1, CAP1, STK25, CCT4, CCT2, NRG3, FRS3, MALT1, JTB, COPS8, DBF4, RCAN3, CDC37, MAP4K5 |
1641 | GO:0051223 | 0.00 | 2.00 | 30.17 | 44 | 82 | regulation of protein transport | ADCY5, ARL2, ARNTL, BNIP3L, CACNA1A, CDKN2A, CHRM3, CNR1, CRP, EFNA5, EPHA5, GJA5, GLP1R, GNAS, FOXA2, ITPR1, ITPR2, KCNC2, KCNS3, LLGL2, PAM, PDE3B, PIK3C3, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PTPN1, RFX3, SLC2A1, SLC16A1, SNAP25, STXBP1, SYT5, TRAF2, RAB11A, SYT7, HMGN3, NRXN1, ATG5, CLOCK, RAPGEF4 |
1642 | GO:0006139 | 0.00 | 2.00 | 38.00 | 56 | 109 | nucleobase-containing compound metabolic process | ACPP, ALDOB, ALDOC, AOX1, ATP1A2, ATP2B2, ATP6V1A, ATP6V1B1, ATP6V1B2, BAD, CACNB4, COX15, CPS1, CTNS, DLG2, DLG3, DPAGT1, ENO2, ENO3, FUT8, GAMT, GAPDH, HMGCR, IDH1, KCNQ1, LDHA, MDH1, MDH2, ALDH6A1, OGDH, PFKFB1, PFKFB2, PGAM2, PGK1, PGM1, PPP2R5D, PTGDR, RPE, SDHC, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, TAZ, TPMT, UQCRC1, UQCRC2, UQCRH, PDHX, DIRAS3, SLC28A1, TP53I3, GNE, PEMT, NUDT4 |
1643 | GO:0021549 | 0.01 | 2.00 | 17.20 | 25 | 46 | cerebellum development | AARS, ABAT, ABL1, ABL2, AGTR2, ARCN1, RERE, ATP2B2, CACNA1A, LPAR1, GRID2, HNRNPD, KCNC1, OGDH, PTN, PTPRS, SCN5A, SSTR2, NR2C2, WNT1, USP9X, FZD4, ATRN, NRXN1, ATG7 |
1644 | GO:0048199 | 0.01 | 2.00 | 17.20 | 25 | 46 | vesicle targeting, to, from or within Golgi | ARCN1, AREG, ARF1, CD59, COPA, CSNK1D, CTSZ, GOLGA2, GRIA1, LMAN1, PPP6C, RAB1A, TRAPPC2, TRAPPC10, CUL3, USO1, COPB2, GOSR1, SEC22B, GOSR2, PREB, SEC24B, SEC23A, SEC24A, TMED2 |
1645 | GO:0007265 | 0.00 | 2.00 | 83.71 | 121 | 225 | Ras protein signal transduction | ABCA1, ADRA2A, AGTR1, ANGPT1, ARAF, ARHGAP4, ARHGAP6, ARHGDIB, BCR, CALM1, CALM3, CAMK2A, CDK2, CDKN1A, CDKN2A, CHUK, CRKL, CSF2RB, DHCR24, DOK1, HBEGF, DUSP5, EDNRA, ERBB2, EREG, FGD1, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FYN, GDI1, GNB1, GRB2, GRIN2A, IL2RA, KIT, LIMK1, MARK3, PEBP1, PPP5C, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTK2, PTPRA, RAF1, RALA, RAP2A, RAP2B, RB1, RDX, RIT1, RREB1, RSU1, SDCBP, SHC1, SOS1, SOS2, UBB, VAV1, ARHGEF5, FGF23, MAPKAPK5, RFXANK, PEA15, CTNNAL1, ARHGEF7, KALRN, DOK2, USP8, ARHGEF1, ARHGEF2, CYTH3, GRAP2, ARHGAP29, ARHGEF6, PSMF1, NRG2, AATK, RALGPS1, RAPGEF2, ARHGEF11, ARHGEF17, PSMD6, RBX1, AKAP9, G3BP1, FARP1, PSME3, PSMD14, RAPGEF3, CDC42EP2, VAV3, ARFGEF2, ARFGEF1, CDC42EP3, GRAP, FRS3, AKAP13 |
1646 | GO:2001257 | 0.03 | 2.00 | 13.08 | 19 | 35 | regulation of cation channel activity | BMP4, CASQ2, STOM, GSTM2, HRC, KCNE1, KCNJ1, KCNJ11, KCNQ1, KCNS2, NTSR1, PDE4D, PLN, SUMO1, KCNAB1, GSTO1, AKAP7, AKAP6, TRDN |
1647 | GO:1901698 | 0.01 | 2.00 | 17.64 | 26 | 50 | response to nitrogen compound | ADAR, ATRX, BMP4, DDX1, DPEP1, GSTM1, GUCY1B3, IFIT1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IL1R1, KCNJ8, SMAD1, SMAD3, MAP3K5, MAPK8, EIF2AK2, STAT6, TRAF2, TNFSF4, DDX21, CHEK2 |
1648 | GO:0019693 | 0.00 | 1.99 | 45.48 | 66 | 123 | ribose phosphate metabolic process | ALDOB, ALDOC, ARNT, ATP1A2, ATP2B2, ATP6V1A, ATP6V1B1, ATP6V1B2, BAD, TSPO, CACNB4, COX4I1, COX8A, COX15, CTNS, DLG2, DLG3, ENO2, ENO3, FZD2, GAPDH, GPD1, HIF1A, HMGCR, HSPA8, IGF1, INS, LDHA, OGDH, P2RX7, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, PF4, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PGM1, PPP2R5D, PRKAA1, PRKAG1, RPE, SDHC, SNCA, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, TAZ, UQCRC1, UQCRC2, UQCRH, OGT, PDE5A, HDAC4, RAPGEF3, PDE10A |
1649 | GO:0048514 | 0.02 | 1.99 | 15.10 | 22 | 41 | blood vessel morphogenesis | PRDM1, COL3A1, EYA1, HPGD, HES1, SMAD7, CITED1, NTRK2, PRRX1, PTGER4, PTPRJ, SIX1, NR2F2, TNNI3, WNT11, FZD4, FOXN1, QKI, RAPGEF2, CUL7, SEC24B, GLMN |
1650 | GO:0001738 | 0.03 | 1.99 | 13.09 | 19 | 35 | morphogenesis of a polarized epithelium | ABL1, ABL2, CDC42, DAB2, DLG3, GPC4, FZD2, LAMA5, RAC1, RYK, WNT11, FZD6, FZD7, TP63, NUMB, SLC9A3R1, GPC6, SEC24B, RAB10 |
1651 | GO:0033013 | 0.03 | 1.99 | 13.09 | 19 | 35 | tetrapyrrole metabolic process | ALAD, ALAS1, ALAS2, AMBP, BLVRA, BLVRB, TSPO, COX15, CPOX, CTRB1, GIF, HMBS, HPX, SLC11A2, ABCD4, UROS, CUBN, SUCLA2, ABCB6 |
1652 | GO:0002504 | 0.01 | 1.99 | 22.07 | 32 | 59 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | ARF1, CANX, CENPE, AP1S1, AP2S1, CLTA, CTSD, CTSE, CTSV, DYNC1H1, DYNC1I1, DYNC1I2, DNM2, FCER1G, HLA-DQA1, KIF5A, KLC1, RAB7A, DYNLL1, CTSF, AP1S2, AP1M1, KIF3B, AP1M2, ACTR1B, SEC24B, IFI30, SEC23A, DCTN6, SEC24A, KIF2C, KIF3A |
1653 | GO:0006446 | 0.01 | 1.99 | 22.07 | 32 | 59 | regulation of translational initiation | ATF4, DAZ1, DDX1, EIF2S1, EIF2B1, EIF4A1, EIF4EBP1, EIF4G1, EIF4G2, EIF5, HSPB1, EIF3E, EIF2AK2, RARA, RBM4, RPS6KB1, RPS6KB2, RXRA, EIF4H, EIF4EBP3, EIF3G, EIF3J, EIF4G3, EIF2B3, EIF2B2, EIF2B5, EIF2AK3, EIF5B, EIF1, EIF1B, EIF3M, KHDRBS1 |
1654 | GO:0051146 | 0.00 | 1.99 | 41.51 | 60 | 111 | striated muscle cell differentiation | ACTG1, ACVR1, AGTR2, BCL2, BMP4, CACNB4, CASQ1, CASQ2, CAV2, CAV3, CCNB1, CD53, CFL2, CHUK, CXADR, FLNC, FLT3LG, GATA4, GATA6, KAT2A, GPX1, NRG1, IGF1, IGF2, IGFBP5, RBPJ, ITGB1, KRAS, KRT19, YBX1, PRKAR1A, RARA, RARB, RB1, RXRA, RYR1, SORT1, SGCB, SLC9A1, SRF, TMOD1, TNNT2, TSC1, WNT1, CSRP3, SORBS2, TNFSF14, CFLAR, HDAC3, DYRK1B, CTDP1, AKAP6, ATG5, GDF15, HDAC4, MAML1, SPEG, ATG7, AFG3L2, BVES |
1655 | GO:0030010 | 0.01 | 1.99 | 17.95 | 26 | 48 | establishment of cell polarity | ARF6, KRIT1, CENPA, EPHB1, EYA1, PTK2B, FLOT2, LLGL2, NUMA1, PRKCI, PRKCZ, PTK2, CCL21, FSCN1, STK11, DYNLT1, WEE1, ARHGEF2, ZW10, CYTH3, SLC9A3R1, ARHGEF11, RNF41, SPRY1, ARFGEF1, RAB10 |
1656 | GO:0097190 | 0.00 | 1.98 | 32.38 | 47 | 88 | apoptotic signaling pathway | ANXA6, ARHGAP4, BNIP3L, BTK, CD3E, CD5, CD28, TNFRSF8, CD38, CD70, CRH, DCC, EYA2, FGD1, FGFR3, HIP1, IFNG, KRT18, KITLG, TNFRSF11B, P2RX4, P2RX7, PAWR, PTGIS, RAC1, DPF2, SORT1, SOS1, SOS2, SPN, TNFRSF4, VAV1, TNFRSF6B, TNFRSF18, TNFRSF10D, ARHGEF7, KALRN, ARHGEF6, BAG3, KIAA0141, ARHGEF11, ARHGEF17, CASP8AP2, PDCD6, RNF41, VAV3, AKAP13 |
1657 | GO:0050863 | 0.00 | 1.98 | 24.16 | 35 | 65 | regulation of T cell activation | BAD, CAMK4, CD3D, CD3G, CD5, CDC42, CTLA4, CYLD, DPP4, EGR3, FLOT2, FYN, GRB2, HLA-DQA1, HLX, IFNA2, PRKCZ, RAC1, RAG1, RARA, CCL21, SOD1, ZEB1, TRAF2, VAV1, FOXN1, AP3B1, TNFSF14, AP3D1, SOCS6, GRAP2, SOX13, IKZF1, MALT1, SPINK5 |
1658 | GO:0045089 | 0.00 | 1.98 | 68.07 | 98 | 182 | positive regulation of innate immune response | BIRC2, BIRC3, XIAP, BTK, CALM1, CALM3, CD86, CD36, CHUK, CREB1, ATF2, CTSK, CYBA, CYLD, DMBT1, DUSP4, ELK1, EP300, EREG, F2RL1, FCER1G, FYN, GFI1, HCK, UBE2K, HPX, ICAM2, ICAM3, IFI16, IL1B, IL12B, IRAK1, IRAK2, IRF1, ITGAM, ITPR1, ITPR2, JUN, KRAS, LTF, PIK3C3, PPP2R5D, PPP3R1, PRKACB, PRKACG, PRKCD, PRKCE, MAPK8, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PVR, RAF1, RELB, RPS6KA1, RPS19, SEC14L1, SKP1, STAT5B, TNFAIP3, HSP90B1, TYRO3, UBB, UBE2D2, VAV1, CUL1, IKBKG, RIPK1, RIPK2, UBA3, PSMF1, PSMD6, TRIL, NR1H4, PSME3, PSMD14, TNIP1, CNPY3, MALT1 |
1659 | GO:0045814 | 0.00 | 1.98 | 27.68 | 40 | 74 | negative regulation of gene expression, epigenetic | CCNH, DNMT1, DNMT3B, ERCC3, HIST1H2AE, HIST1H2AD, H2AFZ, HMGA1, JARID2, PHF2, SUV39H1, TBP, TTF1, UBTF, HIST1H4I, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, HAT1, EED, SAP30, HIST1H3F, HIST1H2AG, TAF1C, TAF1B, TAF1A, SAP18 |
1660 | GO:0001755 | 0.03 | 1.98 | 13.83 | 20 | 37 | neural crest cell migration | ACVR1, EDN3, EFNB1, HIF1A, ISL1, LAMA5, KITLG, NRTN, PAX3, SOX10, TWIST1, SEMA3B, SEMA5A, SEMA3E, ZEB2, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B |
1661 | GO:0006875 | 0.01 | 1.98 | 22.73 | 33 | 62 | cellular metal ion homeostasis | ABCB7, ACO1, ALAS2, APLP2, ARF1, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, BMP6, FTL, HIF1A, HPX, LTF, NUBP1, SLC11A2, S100A8, S100A9, SCO1, SLC11A1, SOD1, SLC30A2, SLC30A3, SLC30A4, AP3D1, ATP6V0D1, ABCG2, ATP6V1G1, HEPH, ABCB6 |
1662 | GO:0002520 | 0.00 | 1.97 | 162.12 | 231 | 434 | immune system development | ABL1, ABL2, ACTN1, ACVR2A, ADAR, ADD1, JAG1, ALAS2, ANGPT1, ANXA1, APCS, ARNT, ATM, ATP6AP1, AXL, BAD, BAX, BCL2, BCL3, BGLAP, PRDM1, BMI1, BMP4, BRCA2, ZFP36L2, BTK, C1QC, CA2, CACNB4, CAMK4, CASP9, RUNX2, CBFB, CD3D, CD4, CD8A, CD28, CD80, TNFSF8, CDC42, CDK6, CDKN2A, CEBPE, CHD2, CHUK, CR2, CREB1, CRKL, CSF1R, CTLA4, CYLD, ACE, DNASE2, GPR183, EEF2, EGR3, EPHA2, EML1, EP300, EPHB3, ERBB2, ERCC1, ETS1, ETV6, F2RL1, PTK2B, FCER1G, FGF3, FLI1, FLT3, FLT3LG, FSHB, FSHR, GABPA, GAS6, GFI1, GPC3, GNAS, HCLS1, HHEX, HIF1A, HLX, ONECUT1, HES1, IFI16, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, RBPJ, IHH, IL1B, IL10, IL12B, IL15, IL17A, INHA, IRF1, ITGA4, ITGB1, JARID2, JUN, KDR, KIT, LTF, SMAD3, CD46, KITLG, SLC11A2, NTRK1, PBX1, PDE1B, PF4, PGM3, PIP4K2A, PRKCZ, EIF2AK2, PRKX, PSEN1, PTGER4, PTPN6, RAF1, RAG1, RAG2, RARA, RB1, RELB, REST, RHAG, RPL22, RPS19, SATB1, SRSF4, SIX1, SLC8A3, SOD1, SOS1, SOS2, SP1, SPN, SRF, TROVE2, STAT5B, STAT6, STK11, ADAM17, TAL1, TAZ, ZEB1, KLF10, TOP2A, TPD52, TSC1, TNFSF4, TYR, TYRO3, TYROBP, UNG, VCAM1, WHSC1, WNT1, WNT2B, XRCC5, ZNF16, FZD5, HIST1H4I, PICALM, FZD7, FZD8, FZD9, GFI1B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, FOXN1, OGT, PIR, AP3B1, CDK13, RIPK1, TNFSF9, RIPK2, INPP4B, ARHGEF7, AP3D1, TNFSF18, RNF8, KRT75, CCNB2, EXO1, GPR55, KLF4, IL27RA, SOX13, CTR9, HDAC4, ZBTB24, GAB2, FARP2, ABI1, BCL2L11, SH2B3, TSPAN2, WASF2, RNF41, DHRS2, PRG4, TRIB1, LRRC17, FSTL3, IKZF1, KLF2, CITED2, ARIH2, TACC3, CXCL13, GAS2L1, EBP, TOB2, MALT1, PRDX3, SPINK5, BVES |
1663 | GO:0001654 | 0.00 | 1.97 | 69.57 | 100 | 186 | eye development | ACHE, ACTL6A, ACVR2B, ACVRL1, JAG1, ALDH1A3, AQP5, ATP2B1, BAX, BBS4, BCL2, PRDM1, BMP4, BMP6, BMPR2, CDK2, CDK4, CNTF, COL5A2, CRX, CRYBA1, CRYBA4, CRYGB, CTNS, EPHA2, FBN1, EFEMP1, FGFR3, GNAT1, GNAT2, GNB1, GNGT1, GPD2, GPM6A, ARHGAP35, HIF1A, HMGN1, HSF4, IHH, IMPDH1, IMPDH2, JUN, KDR, LIM2, SMAD3, NRL, NTRK2, NTRK3, OTX2, PAX4, SERPINF1, PRKCI, PSEN1, PTN, PTPRM, RARA, RARB, RCN1, PRPH2, RPGR, RPE65, RPL24, RRM1, RS1, RXRA, SIX3, SMARCA4, SMARCD3, SOX1, SOX2, SOX9, SOX11, SP1, SRF, STAT3, ZEB1, TMOD1, TUB, TULP1, TULP3, TWIST1, VIM, WNT2, WNT2B, YY1, FZD5, FZD4, BCAR3, BFSP2, NRP1, ALDH1A2, KLF4, SLC4A7, IFT140, ZEB2, NR2E3, IRX5, IKZF1, VAX1, KERA |
1664 | GO:0031325 | 0.00 | 1.97 | 155.22 | 224 | 443 | positive regulation of cellular metabolic process | ABAT, ABL1, ABL2, ACACB, ACLY, ACVR2B, ADCY3, ADCY5, ADCY6, ADCY9, ALOX12, ANG, ANGPT1, APAF1, BIRC2, BIRC3, XIAP, ARAF, ATP6AP1, CCND1, BCL2, BID, BMI1, BMP1, BMP8B, BOK, C3, CASP1, CASP9, CAV2, CCK, CCND3, CD44, CD63, CENPE, CNTF, COL4A3, COMT, CRKL, CSF1R, CSF2RB, CSPG4, CTF1, CTGF, CTSH, ACE, DNMT1, DNMT3B, HBEGF, DUSP5, DYRK1A, GPR183, LPAR1, EDN3, EEF1A2, EFNA1, EFNA5, EMP2, EPHA7, EPHA8, F3, ACSL1, FBLN1, FGA, FGF3, FGF5, FGFR3, FGG, FGR, FLT1, FLT3, FLT3LG, FLT4, FPR1, FYN, GAS6, GDF9, GFRA2, GNG3, RAPGEF1, GRIN2A, GRM1, HIST1H1B, HIP1, UBE2K, HMGCR, HPRT1, HPX, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGFBP3, IL2RA, IL13, IL18, INHA, ITGA1, ITGA5, ITGB1, JARID2, KISS1, KLKB1, MARK3, MAP3K5, MAP3K11, SLC11A2, NTRK3, TNFRSF11B, P2RX1, PEBP1, PCOLCE, PDE6G, PDE6H, ENPP2, PFN2, PIM1, PPP5C, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PSAP, PTPRA, RAB1A, RAP2A, RAP2B, RASA2, RYK, S100A7, SERPINB3, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SDCBP, SELE, SEMG1, SFRP4, STIL, SOS1, STK10, XCL2, ADAM17, CNTN2, NR2F1, CLEC3B, TPD52L1, TTK, TNFRSF4, UBE2L3, VEGFB, VEGFC, VTN, ZNF16, AIMP2, CDK2AP1, BCAR3, CDC14B, PDE5A, PEA15, EED, CRADD, TNFSF10, TNFRSF6B, TNFRSF18, TNFRSF10B, TNFRSF10A, NRP1, UNC119, LATS1, AIFM1, CRLF1, GPR55, S1PR2, TAOK2, PICK1, AKAP6, GDF15, BAG4, NRG2, TRAF4, RAPGEF2, SLK, ATG13, IST1, RB1CC1, OXSR1, TNFSF15, RBX1, CASP8AP2, ABI1, HDAC6, PDCD6, BCL2L10, BCL2L11, TOM1L1, AKAP9, RASA4, SORBS3, TNK2, RAMP3, CNPY2, ABCA7, PIAS3, VAV3, STK25, SEMA4D, ARL6IP5, NRG3, FRS3, JTB, COPS8, IL24, ADRM1, BVES, MAP4K5, FZD10 |
1665 | GO:0032272 | 0.03 | 1.97 | 13.84 | 20 | 37 | negative regulation of protein polymerization | ADD1, BBS4, CAPG, CAPZA1, CAPZB, EPS8, PFN1, PFN2, PRKCD, RDX, SGK1, SNCA, TBCD, TMOD1, VDAC2, VIL1, SLIT2, ARFGEF1, AVIL, STMN2 |
1666 | GO:1903729 | 0.03 | 1.97 | 13.84 | 20 | 37 | regulation of plasma membrane organization | ARF6, BCL2L1, DAB2, DNM2, EPHA2, ACSL3, IFNG, ITGA3, ITGB1, PRKCD, PRKCI, S100A9, VIL1, NUMB, VAMP8, NRXN1, TMEM59, RAMP3, SORBS1, RER1 |
1667 | GO:0043405 | 0.00 | 1.97 | 42.23 | 61 | 114 | regulation of MAP kinase activity | ADRA2A, ALK, CAV3, CD81, CSPG4, GADD45A, DUSP1, DUSP4, LPAR1, EDN3, EFNA1, ERN1, PTK2B, FLT3, FPR1, GNG3, GPS2, HGF, HMGCR, IGF1R, IL1B, ILK, IRAK1, IRAK2, ITGA1, NTF3, NTRK3, P2RX7, PDE6G, PDE6H, PIK3CB, PPP2R1A, PRKAA1, PRKCD, PTPN1, PTPN6, PTPRJ, RGS2, RPS3, S100A12, SERPINB3, SOD1, TP73, TPD52L1, TRAF2, TSG101, FZD5, ARHGEF5, FZD4, FZD8, IKBKG, MAPKAPK5, PDE5A, RIPK1, RIPK2, S1PR2, ZEB2, TRIB1, SPRY1, MAP4K5, FZD10 |
1668 | GO:0032387 | 0.00 | 1.97 | 28.42 | 41 | 76 | negative regulation of intracellular transport | ANGPT1, BARD1, BCL2, BST2, CALM1, CALM3, CASQ2, CD36, CYLD, GAS6, GDI1, GSTM2, IL10, IL13RA2, INSIG1, KCNE1, TONSL, NTSR1, PLN, PPM1A, PPM1B, RANGAP1, SFRP5, SP100, TRIP6, AKAP1, DYRK2, OGT, TNFSF14, ITGB1BP1, SLC9A3R1, GSTO1, LITAF, BAG4, KEAP1, APC2, TRDN, ACAA2, TACC3, CREB3, OS9 |
1669 | GO:0009150 | 0.02 | 1.97 | 16.56 | 24 | 45 | purine ribonucleotide metabolic process | ATP2B2, CACNB4, DLG2, DLG3, FZD2, HMGCR, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, PF4, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, PDE5A, RAPGEF3, PDE10A |
1670 | GO:0009161 | 0.00 | 1.97 | 49.37 | 71 | 132 | ribonucleoside monophosphate metabolic process | ADSL, ADSS, AK1, AK2, AK4, ALDOB, ALDOC, AMPD1, AMPD2, APRT, ARNT, ATP1A2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V0A1, ATP5O, BAD, TSPO, COX4I1, COX8A, COX15, CTNS, DLG2, DLG3, ENO2, ENO3, GAPDH, GPD1, HIF1A, HPRT1, HSPA8, IGF1, IMPDH1, IMPDH2, INS, LDHA, LDHC, OGDH, P2RX7, PFAS, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PGM1, PPP2R5D, PRKAA1, PRKAG1, SDHC, SNCA, STAT3, TAZ, UPP1, UQCRC1, UQCRC2, UQCRH, OGT, ATP5J2, HDAC4, SLC25A13, ATP5H, ATP5L |
1671 | GO:0032940 | 0.00 | 1.97 | 32.44 | 47 | 89 | secretion by cell | A2M, ACTN1, ALB, ANXA3, APP, AXL, SERPING1, CALM1, CALM3, CALU, CD9, CD63, CLU, CTGF, FGF7, GCGR, HCK, HGF, HRG, IGF2, KIT, KNG1, LAMP2, P2RX1, PCSK6, SERPINE1, PF4, PFN1, PSAP, SELP, SOD1, SPARC, TUBA4A, TYRO3, VEGFB, LAT2, RAB11A, SCRN1, ABCC4, CAP1, ARFGEF2, ARFGEF1, EXOC5, YKT6, COPS5, RAB31, CORO1A |
1672 | GO:0008544 | 0.00 | 1.96 | 25.65 | 37 | 69 | epidermis development | AARS, ALDH3A2, STS, BCL2, COL17A1, CST6, CTGF, CTSV, DBI, EDA, EMP1, FGF7, FLOT2, GJB5, GNAS, IGF1R, IGFBP5, KRTAP5-9, KRT5, KRT9, KRT15, KRT32, KRT34, KRT83, LAMA3, LAMA5, NTF3, NTF4, OVOL1, PTHLH, RBP2, SATB1, SNAI1, SOX9, FZD6, EDAR, SOX21 |
1673 | GO:0046328 | 0.00 | 1.96 | 29.17 | 42 | 78 | regulation of JNK cascade | AMBP, CDC42, CTGF, GADD45A, EPHB1, ERCC6, ERN1, F2RL1, PTK2B, FLT4, GPS2, IGF1R, IL1A, IL1B, MAP3K5, MAP3K11, PARK2, PER1, PTPN1, RAP2A, RPS3, SERPINB3, CCL21, SDCBP, TP73, TPD52L1, TRAF2, FZD5, ARHGEF5, FZD4, FZD7, FZD8, RIPK1, RIPK2, HDAC3, TAOK2, TRAF4, ZEB2, ZMYND11, COPS5, MAP4K5, FZD10 |
1674 | GO:0061387 | 0.01 | 1.96 | 19.42 | 28 | 52 | regulation of extent of cell growth | ABL1, ARHGAP4, BMPR2, DNM2, CTTN, GOLGA4, NRG1, ILK, LIMK1, NRCAM, NTRK3, RNF6, SEMA3F, SRF, CDKL5, TNR, SEMA3B, RAB11A, NRP1, SEMA5A, SLIT2, AATK, SEMA3E, SEMA3A, SEMA6C, SEMA6B, SEMA4F, SEMA4B |
1675 | GO:0045893 | 0.00 | 1.96 | 79.82 | 115 | 219 | positive regulation of transcription, DNA-templated | AGTR2, ALK, ANXA3, BRCA2, BRDT, BTK, CAMK4, CAMK2A, CAT, CCNE1, CD80, CD86, CD38, CDH1, CDK2, CDX2, CHEK1, CLU, COL1A1, CREBL2, CTH, DAB2, DNM2, EDA, EPHA5, ERBB2, ERCC6, F2R, FGF7, FZD2, HMGN1, HNF4G, HNRNPD, PRMT2, ICAM1, IFNA2, ILF3, ILK, ING2, INS, IRAK1, IRAK2, KIT, KRAS, LTF, AFF1, NTRK1, PHF2, PPM1A, PRKCI, PRKCQ, PRKCZ, EIF2AK2, RELN, PSEN1, PSMA6, PTEN, RAN, RFXAP, RNF6, RPS3, RREB1, S100A8, S100A9, S100A12, SMARCA1, SMARCC2, SMARCD1, SMARCD3, SNAI1, SP100, SRY, TRIM21, TBP, NR2F2, TNNI2, TRAF1, TRAF2, UBTF, WNT11, ZIC2, ZNF711, TRIM25, ZBTB17, ZXDA, BRPF1, ARHGEF5, FGF23, PICALM, FZD4, FZD7, KLF7, TRADD, EDF1, TRIM24, CFLAR, TNFSF18, BAZ1B, DYRK1B, RNF14, ZNF516, ARHGEF11, NR1D2, RNF41, TRIM13, TRIM22, MAD2L2, TRIM38, DEAF1, TRIM16, MALT1, PRDX3, PIM2, SUPT16H, CHEK2 |
1676 | GO:0010951 | 0.00 | 1.96 | 55.73 | 80 | 149 | negative regulation of endopeptidase activity | A2M, AHSG, AKT2, AMBP, BIRC2, BIRC3, XIAP, BIRC5, APLP2, APP, AVP, BST2, SERPING1, C3, SERPINH1, CD44, COL4A3, COL6A3, CSNK2A1, CST6, DHCR24, DPEP1, SERPINB1, GAS6, SFN, GPX1, SERPIND1, HGF, HRG, IFI16, IGBP1, ITIH1, ITIH3, ITIH4, KNG1, PEBP1, SERPINE1, SERPINB2, SERPINA5, SERPINF1, PI3, SERPINA4, SERPINB5, SERPINB8, SERPINB9, SERPINB10, SERPINB13, SERPINI2, PZP, RAF1, RAG1, RENBP, RPS6KA1, SERPINB3, SERPINB4, SLPI, SNCA, SPINK1, SPINT1, SPOCK1, SERPINA7, TRAF2, VIL1, VTN, PICALM, RECK, SERPINB7, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR, USP14, KLF4, PSMF1, SPINT3, PRDX3, SPINK5 |
1677 | GO:0050728 | 0.01 | 1.96 | 19.43 | 28 | 52 | negative regulation of inflammatory response | ADRB2, APCS, APOA1, BCR, CNR2, CX3CR1, ETS1, GHSR, IL2RA, INS, ISL1, KRT1, SMAD3, SERPINF1, PRKCD, PROC, PTGER4, PTGIS, RPS19, TNFAIP3, TNFAIP6, TNFRSF1A, TNFRSF1B, TYRO3, SOCS3, KLF4, SLIT2, CALCRL |
1678 | GO:0051960 | 0.00 | 1.96 | 141.92 | 202 | 380 | regulation of nervous system development | ABL1, ABL2, ADCY6, JAG1, APP, ARF1, ARF6, ARHGAP4, ARNTL, ASCL1, ASCL2, ATOH1, ADGRB1, ADGRB2, BCL2, BMP4, BMP6, BMPR1A, BMPR2, TSPO, CACNA1A, CDC20, CHN1, CHRNB2, CNR1, CNTF, COL3A1, CREB1, CRX, CTNNA1, CX3CR1, BRINP1, DCC, DDX6, DNM2, DNMT3B, DPYSL3, DRD3, LPAR1, EFNA1, EFNA5, EIF4E, EIF4G1, EMX1, CTTN, EPHA7, EPHB1, EPHB2, EPHB3, ETV5, EYA1, F2, PTK2B, EFEMP1, FGFR3, FYN, FZD2, GAK, GDI1, GFAP, GFI1, GHSR, GOLGA4, RAPGEF1, GRID2, GRN, ARHGAP35, HIF1A, FOXA2, HOXD3, HES1, IFRD1, IGF1, IL1B, ILK, ISL1, ITGA3, ITGB1, KIT, LIMK1, CAPRIN1, NRCAM, NTF3, NTF4, NTRK1, NTRK2, NTRK3, OMG, OPA1, OXTR, P2RY2, PALM, PARK2, PBX1, PCM1, PCP4, SERPINF1, PRRX1, PRKACB, PRKCI, PRKD1, RELN, PSEN1, PTK2, PTN, PTPRD, RAC1, RAC3, RAP1GAP, RAP2A, REST, RHEB, RNF6, SALL1, CX3CL1, SDC2, SEMA3F, SGK1, SIX1, SIX3, SLIT3, SMARCD3, SNAP25, SOX2, SOX3, SOX9, SOX10, SOX11, SPINT1, SPOCK1, SRF, STAR, STAT3, CDKL5, STK11, SYT1, SYT4, CNTN2, ZEB1, DYNLT1, TNR, TP73, TPBG, TTC3, TULP3, VEGFC, VIM, WNT2, XRCC2, XRCC5, RNF112, SEMA3B, RND2, SOX14, CAMK1, CHRD, NUMB, RAB11A, NRP1, KAT2B, CPNE1, PHOX2B, SEMA5A, ARHGEF1, CBFA2T2, ARHGEF2, NUMBL, KLF4, NREP, SLIT2, NRXN3, NRXN1, ADAMTS1, BAG5, AATK, RAPGEF2, RIMS2, SEMA3E, IST1, CUL7, KIAA0319, OLIG2, KATNB1, HMG20B, HMG20A, SEMA3A, SEC24B, BAIAP2, STK25, CARM1, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, AVIL, TBR1, NRG3, VAX1, STMN2, CIT, IL1RAPL1 |
1679 | GO:0006793 | 0.00 | 1.96 | 624.97 | 847 | 1671 | phosphorus metabolic process | ABCA1, ABL1, ABL2, ACACB, ACHE, ACLY, ACP1, ACPP, ACVR1, ACVR2A, ACVR2B, ACVRL1, ACYP1, ADAM10, ADAR, ADARB1, ADCY3, ADCY5, ADCY6, ADCY9, ADM, ADRA1B, ADRA2A, ADRB2, ADSL, ADSS, AGTR2, AHSG, AK1, AK2, AK4, AKT2, ALDOB, ALDOC, ALK, ALPI, ALPPL2, AMBP, AMHR2, AMPD1, AMPD2, ANG, ANGPT1, BIRC5, APLP1, APLP2, APOA1, APP, APRT, ARAF, AREG, ARF1, ARNT, ARR3, ATM, ATP1A1, ATP1A2, ATP2B2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V0A1, ATP6AP1, ATP5O, ATR, AVP, AVPR2, AXL, BAD, BARD1, BAX, CCND1, BCL2, BCR, BDKRB2, BLK, BMP1, BMP3, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, BNIP2, BTK, BUB1B, TSPO, C3, CACNB4, CALCR, CALM1, CALM3, CAMK4, CAMK2A, CAT, CAV2, CAV3, CCK, CCNB1, CCNC, CCND3, CCNE1, CCNG1, CCNH, CCNT1, CCNT2, CD3E, CD4, CD80, CD36, ENTPD2, CD44, CD81, CDA, CDK11B, CDC25A, CDC25C, CDC42, CDK2, CDK3, CDK4, CDK6, CDK8, CDK9, CDKN1A, CDKN2A, CENPE, CHAD, CHAT, CHEK1, CHKB, CHUK, CISH, CKM, CKS1B, CKS2, CLU, CLK1, CLK3, CCR5, CNP, CNTF, COX4I1, COX8A, COX15, CPS1, CREB1, ATF2, CREBL2, CRH, CRKL, CRY1, CRY2, CRYBA1, CSF1R, CSF2RB, CSNK1D, CSNK1G2, CSNK1G3, CSNK2A1, CSNK2A2, CSPG4, CTF1, CTGF, CTNS, CTPS1, CTSH, DAB2, DGKA, DGKB, DGKQ, DAPK3, DBI, DCN, ACE, DCX, GADD45A, DHFR, DLG2, DLG3, DRD3, DRD5, HBEGF, DTYMK, DUSP1, DUSP4, DUSP5, DUT, DYRK1A, GPR183, TYMP, LPAR1, EDN3, EDNRA, EEF1A2, EFNA1, EFNA5, EIF2S1, EPHA2, ELK1, EMP2, ENO2, ENO3, EPHA1, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, ERBB2, EREG, EYA4, ERCC3, ERCC6, ERG, ERN1, ESR1, EYA1, EYA2, EYA3, F2, F2R, F2RL1, ACSL1, ACSL3, ACSL4, PTK2B, FBLN1, EFEMP1, FDFT1, FDPS, FGA, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FGG, FGR, FLT1, FLT3, FLT3LG, FLT4, FPR1, FRK, FSHR, FYB, FYN, FZD2, G6PC, GAK, GALK1, GALK2, GALR1, GAPDH, GAS6, GATA6, GCG, GDF9, GFRA2, GHRH, GHRHR, GK2, GLP1R, GNAL, GNAQ, GNAS, GNG3, SFN, GP1BA, GPD1, GPD2, GPLD1, GRK6, GPS2, GPX1, GRB2, RAPGEF1, GRIN2A, GRM1, GRM8, GUCA1A, GUCA1B, GUCA2A, GUCA2B, GUCY1B3, GUCY2C, GUCY2F, GUCY2D, HCK, HCLS1, HEXB, HGF, NRG1, HHEX, HIF1A, UBE2K, HMGCL, HMGCR, FOXA2, HPRT1, HPX, HRH1, HRC, HRG, HES1, HSPA8, HSPB1, HSP90AB1, HTR2C, ICAM1, IDH1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGBP1, IGF1, IGF1R, IGF2, IGFBP3, IL1A, IL1B, IL2RA, IL12B, IL12RB2, IL13, IL15, IL18, ILF3, ILK, IMPA1, IMPDH1, IMPDH2, INHA, INPP1, INS, INPP4A, INPPL1, INSL3, INSRR, IRAK1, IRAK2, ISL1, ITGA1, ITGA5, ITGAV, ITGB1, JUN, KCNH2, KDR, KHK, KISS1, KIT, KRAS, LCAT, LDHA, LDHC, LIMK1, LIPC, LIPE, LTF, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MARK3, MDH1, MDH2, MAP3K5, KITLG, CIITA, MAP3K11, PPP1R12A, NRTN, NTF3, NTHL1, NTRK1, NTRK2, NTRK3, NTSR1, OAS2, OGDH, OGG1, TNFRSF11B, OXTR, P2RX7, P2RY1, P2RY11, PEBP1, PRDX1, PALM, PARK2, PAWR, PCP4, CDK17, PCYT1A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE6G, PDE6H, PDE7A, PDE8A, PDE1B, PDK4, ENPP2, ENPP3, PER1, PF4, PFAS, PFKFB1, PFKFB2, PFN2, CDK14, PGAM1, PGAM2, PGK1, PGM1, PGM3, PHEX, PHKA1, PHKA2, PHKB, PHKG1, PIGC, PIK3C2B, PIK3C3, PIK3CB, PIM1, PI4KA, PIP4K2A, PPM1A, PPM1B, PPP1R1A, PPP1R2, PPP2CB, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PPP4C, PPP3R1, PPP5C, PPP6C, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCE, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK8, EIF2AK2, PRKX, PRPSAP1, RELN, PSAP, PSEN1, PSKH1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PSPH, PTAFR, PTEN, PTGER4, PTGIS, PTHLH, PTK2, PTPN1, PTPN4, PTPN6, PTPN7, PTPN13, PTPRA, PTPRD, PTPRE, PTPRH, PTPRJ, PTPRM, PTPRN, PTPRN2, PTPRR, PTPRS, ALDH18A1, PYGL, RAC1, RAC2, RAD51, RAF1, RANBP2, RAP2A, RAP2B, RARA, RASA2, RB1, RBL1, RBL2, RBM4, RCVRN, RGS2, RPE, RPS3, RPS6KA1, RPS6KB1, RPS6KB2, RRM1, RRM2, RYK, S100A7, S100A12, SBF1, SERPINB3, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SDCBP, SDHC, SET, SGK1, SHC1, SHMT1, STIL, SKP1, SLC11A1, SLC20A1, SLC25A1, SNCA, SOD1, SORD, SOS1, SOX2, SOX9, SPINK1, SPN, SRMS, SRPK2, STAT3, STAT4, SULT1E1, AURKA, CDKL5, STK10, STK11, STYX, SULT1A1, SULT1A3, SULT1C2, SULT2B1, XCL2, ADAM17, TAF7, TAZ, NR2F2, TNFAIP3, TNFRSF1A, TNFRSF1B, TOP1, TP73, TPD52L1, NR2C2, HSP90B1, TRAF2, TSC1, TSC2, TSG101, TTK, TWIST1, TNFRSF4, TYMS, TYRO3, UBB, UCN, UGP2, UNG, UPP1, UQCRC1, UQCRC2, UQCRH, UVRAG, VEGFB, VEGFC, VIP, VIPR2, VRK1, VRK2, VTN, WEE1, WFS1, WNT1, WNT11, ZNF16, FZD5, SCG2, EPM2A, ARHGEF5, PDHX, FGF23, HMGA2, CDK2AP1, AKAP1, FZD4, FZD7, FZD8, PIP5K1B, BCAR3, DYRK2, CUL3, CUL1, OGT, PPM1D, PIK3R3, IKBKG, IKBKAP, DGKZ, CAMK1, MAPKAPK5, CDC14B, CDC14A, PDXK, STK16, CDK13, PDE5A, DYNLL1, PEA15, DGAT1, TNK1, URI1, RNGTT, RIPK1, ADAM9, RIPK2, TNFRSF6B, RIOK3, TNFRSF18, TNFRSF10B, TNFRSF10A, DYRK4, SUCLG2, SUCLG1, SUCLA2, TRIM24, CDKL1, DPM2, INPP4B, NRP1, HDAC3, KAT2B, SYNJ1, CPNE1, MBD4, KYNU, RPS6KA4, TNFSF18, KALRN, CDKL2, SOCS3, BAZ1B, PAPSS2, PAPSS1, DIRAS3, UNC119, RGN, LATS1, CCNE2, DYRK1B, CTDP1, DGKI, ARHGEF2, AURKB, VAPB, CRLF1, STK17B, STK17A, ITGB1BP1, GPR55, S1PR2, SOCS6, KLF4, TAOK2, SLIT2, SLC9A3R1, LIPG, EIF2AK3, ARHGEF6, PICK1, AKAP6, PIGL, PSMF1, GDF15, TBPL1, BAG4, TP53I3, NRG2, ATP5J2, MINPP1, GABBR2, CDC42BPB, PRDX6, AKAP12, TRAF4, AATK, GUCA1C, RAPGEF2, SLK, HDAC4, ATG13, DLGAP5, PTDSS1, MAML1, RB1CC1, DNAJC6, ZEB2, PPP1R26, PSMD6, SMG7, NUAK1, FIG4, FAM20B, XYLB, OXSR1, TNFSF15, RBX1, ACOT8, ABI1, GNE, PIGK, TOM1L1, SH2D3C, SH2D3A, RANBP9, COL4A3BP, SGK2, RAD50, AKAP9, ABI2, RASA4, AASS, ATP6AP2, FARP1, SLC25A13, SORBS3, TNK2, RNF41, PSME3, CALCRL, PSMD14, CTDSPL, TRIB1, GLYAT, SPRY1, RAMP2, SPEG, BCKDK, TNIP1, AKR1A1, ABCA7, CEPT1, PEMT, RAPGEF3, CD2BP2, CDIPT, VAV3, MAD2L2, ATP5H, CAP1, STK25, SEMA4D, PRDX4, ARL6IP5, ERN2, HEXIM1, ATP5L, NRG3, ZMYND11, ARPP19, FRS3, PDE10A, SLC26A1, MALT1, JTB, COPS8, PRDX3, SERINC3, ACOT2, COPS5, IL24, PIM2, PTPN21, CIT, PTPRT, CDC37, GLMN, NUDT4, STRAP, MAP4K5, CHEK2, FZD10, AKAP13 |
1680 | GO:0010629 | 0.00 | 1.96 | 41.51 | 60 | 114 | negative regulation of gene expression | A2M, ACACB, AKT2, ANXA7, BIRC2, BIRC3, XIAP, BARD1, BBS2, BBS4, SERPING1, CCNB1, CCNT1, CD3E, CD28, CD59, CDC42, CDK2, CDK9, CDKN1A, CRH, CTGF, DYRK1A, FLOT2, FYN, GAS1, INPPL1, KCNQ1, CD46, NUP88, NUP98, SERPINE1, SERPINF1, PGR, RANBP2, SRSF4, SRSF6, SRSF7, SFSWAP, SLIT3, TMF1, TSN, UCN, VEGFB, NUP214, AAAS, PICALM, FKBP6, SRSF9, CPNE1, SLIT2, TMEM59, NUP155, NUP93, RNF40, CNPY2, GAS2L1, NUP50, RNPS1, NUPL2 |
1681 | GO:0009719 | 0.00 | 1.96 | 71.25 | 104 | 207 | response to endogenous stimulus | ABCA1, ACVR2A, ACVR2B, ACVRL1, AMHR2, APAF1, XIAP, BMP1, BMP3, BMP8B, BMPR1A, BMPR2, CAMK4, CAV3, RUNX2, CBL, CCNC, CCNT1, CCNT2, CD9, CD28, CD80, CD86, CD36, CD44, CD81, CDK8, CDK9, CSNK1D, CX3CR1, DLX5, E2F4, EGR3, FCER1G, FSHB, FUT8, KAT2A, GDF9, GPC3, ONECUT1, HPGD, HES1, RBPJ, IL1R1, ILK, ING2, ITPR1, KCND3, LTBP1, LTBP2, SMAD1, SMAD3, SMAD7, SMAD9, OTX2, PCSK6, SERPINE1, PPP2CB, PPP2R1A, RAP1GAP, RBL1, RPS3, RPS6KB2, XCL1, SDCBP, SOX11, SP1, SPINT1, CLEC3B, VAV1, VIL1, WNT2, ZNF8, SHOC2, USP9X, USP9Y, ITGA8, STK16, CHRD, BECN1, PHOX2B, FIBP, SLC33A1, ITGB1BP1, NREP, CER1, ZFYVE9, ONECUT2, GDF15, BAG4, ADAMTSL2, ZFYVE16, EIF4A3, FGFBP1, SPRY1, FSTL3, CXCL13, GIPC1, FERMT2, RAB35, STMN2, CORO1A, STRAP, ADAMTS7 |
1682 | GO:0030500 | 0.03 | 1.96 | 14.59 | 21 | 39 | regulation of bone mineralization | ACVR1, ACVR2A, ACVR2B, ADRB2, AHSG, BGLAP, BMP4, BMP6, BMPR1A, BMPR2, ECM1, S1PR1, PTK2B, HIF1A, LTF, SMAD3, OMD, P2RX7, SOX9, TWIST1, FGF23 |
1683 | GO:1901989 | 0.03 | 1.96 | 14.59 | 21 | 39 | positive regulation of cell cycle phase transition | ANXA1, BIRC5, APP, CCND1, CDK4, PBX1, PTEN, RAD51C, RAD51B, RB1, RDX, SMARCD3, UBE2E2, ZNF16, CUL4A, CUL3, TP63, RAB11A, PHOX2B, DLGAP5, UBE2C |
1684 | GO:0002230 | 0.00 | 1.95 | 25.06 | 36 | 67 | positive regulation of defense response to virus by host | ANXA5, COX8A, CLDN7, EIF2S1, STOM, FCGR3B, FGF7, SLC37A4, GABRA5, IL12B, KCNQ1, MDH1, NTHL1, PDK4, PEX13, SERPINB10, SCN1A, SLC1A3, SNRPD1, STAT2, ZNF189, CHAF1B, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H3F, CHST3, NUP93, PHYHIP, IST1, FGFBP1, CREB3, TRAF3IP2 |
1685 | GO:0034440 | 0.01 | 1.95 | 20.20 | 29 | 54 | lipid oxidation | ACAA1, ACACB, ACADL, ACADM, ACADS, ACADSB, ACADVL, AKT2, ABCD1, ALOX12, CNR1, CPT1B, CPT2, CRAT, DECR1, ECH1, IVD, PDK4, PEX7, PEX13, PRKAA1, ABCD3, TWIST1, ACOX2, ACOX3, ACOT8, ECI2, SLC25A17, SLC27A2 |
1686 | GO:0009168 | 0.02 | 1.95 | 15.32 | 22 | 41 | purine ribonucleoside monophosphate biosynthetic process | ADSS, AK1, AK2, AK4, APRT, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, ATP5O, IMPDH1, IMPDH2, LDHC, STAT3, ATP5J2, SLC25A13, ATP5H, ATP5L |
1687 | GO:0045732 | 0.00 | 1.95 | 59.47 | 85 | 159 | positive regulation of protein catabolic process | ADRA2A, BARD1, CAV3, CBLB, CCNB1, CD81, CDC20, CDC27, CLU, CSNK1D, CSNK2A1, DAB2, PTK2B, GPC3, GPLD1, DNAJB2, IFNG, IL1B, SMAD7, ATXN3, OAZ1, OAZ2, PARK2, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, RB1, RDX, SGTA, SKP1, SUMO3, SOX9, AURKA, TNFAIP3, TNFRSF1B, UBB, SUMO1, VIP, RAB7A, USP5, CUL3, CUL1, CDC23, ADAM9, CDC16, USP13, RGN, PSMF1, SEC22B, RNF14, DLGAP5, RNF40, KEAP1, PSMD6, KCNE2, PSME3, PSMD14, TRIB1, APC2, ANAPC10, ARIH2, ATG7, UBE2C |
1688 | GO:0006694 | 0.02 | 1.95 | 16.01 | 23 | 43 | steroid biosynthetic process | ACLY, ADM, NR0B1, APOA1, CFTR, CYP3A4, CYP51A1, DHCR24, CYB5R3, FDFT1, FDPS, FDXR, FSHB, HMGCR, HMGCS1, HMGCS2, PBX1, SRD5A1, CNBP, HSD17B6, ACAA2, EBP, C14orf1 |
1689 | GO:1902680 | 0.00 | 1.94 | 272.10 | 381 | 729 | positive regulation of RNA biosynthetic process | ACVR1, ACVR2A, ACVRL1, ADRB2, JAG1, AGTR2, AKT2, ALK, ANXA3, APP, PHOX2A, ARNT, ARNTL, ASCL1, ATF4, RERE, ATOH1, ATRX, BACH1, BCL3, BMP3, BMP4, BMP6, BMPR1A, BMPR2, BRCA1, BRCA2, BRDT, KLF5, BTK, CAMK4, CAMK2A, CAT, RUNX2, CBFB, CCNC, CCNE1, CCNT2, CD3D, CD28, CD80, CD86, TNFSF8, CD38, CD81, CDH1, CDK2, CDK8, CDKN2A, CDX1, CDX2, CDX4, CEBPE, CGA, CHEK1, CHUK, CLU, COL1A1, CREB1, ATF2, CREBL2, CRX, CTH, DAB2, DCN, DDIT3, DDX5, DLX5, DNM2, DRD3, ARID3A, E2F4, EBF1, EDA, S1PR1, EGR2, ELK1, EN1, EPHA5, ERBB2, ERCC6, ESR1, ESRRG, ETS1, ETV4, ETV5, ETV6, EVX1, EYA1, EZH1, F2R, F2RL1, FGF4, FGF7, FLI1, FSHB, NR5A2, NR5A1, FZD2, GABPA, GALR1, GATA4, GATA6, GCG, KAT2A, NR6A1, H2AFZ, HCLS1, HEXB, HGF, NRG1, HHEX, HIF1A, HMGN1, HMGA1, NR4A1, FOXA2, HNF4G, ONECUT1, HNRNPD, HOXC11, HOXD8, HOXD9, HOXD10, PRMT2, HES1, HSF4, ICAM1, IFI16, IFNA2, IFNG, IGBP1, IGF1, IGF2, RBPJ, IHH, IL1A, IL1B, IL10, IL17A, ILF3, ILK, ING2, INS, INSIG1, IRAK1, IRAK2, IRF1, IRF2, IRF5, ISL1, JUND, KIT, KRAS, ABLIM1, LMO1, LTF, LUM, EPCAM, SMAD1, SMAD3, SMAD7, SMAD9, MEOX2, CIITA, AFF1, FOXO4, CITED1, PPP1R12A, NRL, YBX1, NTF3, NTRK1, SIX6, OTX1, OTX2, P2RY1, SERPINE1, PARK2, PAX3, PAX9, PBX1, PCK1, PER1, PF4, PGR, PHF2, PRRX1, PPM1A, PPP3R1, PRKCI, PRKD1, PRKCQ, PRKCZ, EIF2AK2, RELN, PSEN1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PTEN, RAD21, RAF1, RAN, RARA, RARB, RB1, RBL1, RELB, REST, RFX3, RFXAP, RLF, RNF6, RPS3, RPS6KA1, RREB1, RXRA, RXRG, S100A8, S100A9, S100A12, SALL1, SIX1, SIX3, SLC9A1, SLC11A1, SMARCA1, SMARCA2, SMARCC2, SMARCD1, SMARCD3, SNAI1, SOX1, SOX2, SOX9, SOX10, SOX11, SOX12, SP100, SREBF1, SRF, SRY, TRIM21, STAT1, STAT3, STAT4, STAT5B, STAT6, TAF2, TAF7, TAL1, TBL1X, TBP, HNF1A, ZEB1, NR2F2, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C2, TRAF1, TRAF2, TSC2, TWIST1, UBB, UBE3A, UBTF, UCN, NR1H2, USF1, WNT1, WNT2, WNT11, YY1, ZIC1, ZIC2, ZNF711, CNBP, ZSCAN21, TRIM25, ZNF148, ZBTB17, ZXDA, PAX8, FZD5, BRPF1, ARHGEF5, CSRP3, FOSL1, FGF23, HMGA2, NRIP1, PICALM, FZD4, FZD7, FZD8, OGT, ITGA8, IKBKG, CAMK1, STK16, KLF7, RFXANK, TP63, TRADD, EDF1, RIPK1, RIPK2, TRIM24, CFLAR, HDAC3, KAT2B, BUD31, PHOX2B, RPS6KA4, TNFSF18, BAZ1B, CBFA2T2, DYRK1B, ARHGEF2, CCPG1, ITGB1BP1, KLF4, HMGN3, HAND1, EIF2AK3, FHL5, ONECUT2, CLOCK, RNF14, CTR9, ZNF516, HDAC4, BCLAF1, MAML1, ARHGEF11, ZEB2, RNF10, NR1I3, NR1H4, NR1D2, NR2E3, RNF41, TRIM13, FSTL3, TNIP1, IKZF1, TRIM22, KLF2, CITED2, RAPGEF3, RBM14, MAD2L2, SLC30A9, TRIM38, CREB3, DEAF1, USP16, ERLIN1, RBCK1, ARID3B, TRIM16, DMRT2, CTCF, TBR1, STAG2, RAI1, RUVBL2, ARID5A, MALT1, PRDX3, COPS5, PIM2, WWP2, ERLIN2, PSIP1, CHEK2 |
1690 | GO:0031327 | 0.03 | 1.94 | 14.53 | 21 | 40 | negative regulation of cellular biosynthetic process | ADRA2A, APLP1, ATP1A1, TSPO, CACNA1A, LPAR1, EDNRA, GALR1, GHSR, GRM8, IL10, INHA, INS, PALM, PRKAA1, SFTPD, AKR1C3, AKAP6, GABBR2, RAPGEF2, PRG4 |
1691 | GO:0032268 | 0.00 | 1.94 | 260.55 | 366 | 713 | regulation of cellular protein metabolic process | AARS, ABL2, ACO1, ACVR1, ACVR2A, ACVR2B, ACVRL1, ADCY3, ADCY5, ADCY6, ADCY9, ADRA1B, ADRA2A, ADRB2, AGTR1, AGTR2, ALK, ALOX12, APAF1, APOA1, ARNT, ARR3, ATP6AP1, AVPR2, BAD, CCND1, BCL2, BCL3, BID, BMI1, BMP1, BMP3, BMP6, BMP8B, BMPR1A, BMPR2, BOK, CAMK2A, CASP1, CASP9, CAV2, CCK, CCNC, CCND3, CCNE1, CCNG1, CCNH, CCNT1, CCNT2, CD3E, CD4, CD28, CD80, CD36, CDC25A, CDC25C, CDC42, CDK2, CDK4, CDK9, CENPE, CHEK1, CKS1B, CKS2, CNTF, CREBL2, CRH, CRKL, CSF1R, CSF2RB, CSPG4, CTF1, CTGF, CTSH, DAZ1, ACE, DDX1, DDX6, DIO2, HBEGF, DYRK1A, GPR183, LPAR1, EDN3, EDNRA, EEF2, EFNA1, EFNA5, EIF2B1, EPHA2, EIF4A1, EIF4G1, EIF4G2, EIF5, EIF5A, ELAVL1, EMP2, EP300, EPHA7, EPHA8, EPHB1, ERBB2, EREG, ERCC6, ERN1, ESR1, ETF1, F2R, F3, ACSL1, FGA, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FGG, FGR, FLT1, FLT3, FLT3LG, FLT4, FPR1, FSHR, GCG, KAT2A, GDF9, GFI1, GNG3, GOLGA2, GPLD1, GRB2, GRIN2A, GRM1, HIST1H1B, HCLS1, NRG1, HIP1, HPX, HRC, HES1, HSP90AA1, HTR2C, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF2, IL1A, IL2RA, IL12B, IL13, IL15, IL18, INHA, IRAK1, IRAK2, ISL1, ITGA1, ITGA5, ITGB1, KDR, KISS1, KIT, KLKB1, KRAS, LTF, MARK3, MAP3K5, KITLG, MAP3K11, PPP1R12A, SLC11A2, NTRK1, NTRK2, TNFRSF11B, P2RX1, P2RY1, PA2G4, PRDX1, PAWR, PCOLCE, PDE6G, PDE6H, ENPP2, PFN2, PIK3CB, PIM1, PPP1R2, PPP2R1B, PPP2R2A, PPP2R5D, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKD1, MAPK8, RELN, PSAP, PTAFR, PTGER4, PTPRA, RAC1, RAC2, RAD51, RAP2A, RAP2B, RASA2, REST, RPL38, RPS4X, RPS6KB1, RPS6KB2, RXRA, RYK, S100A7, S100A8, S100A9, S100A12, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SEMG1, SHC1, STIL, SLC11A1, SOD1, SOS1, SOX2, SOX9, SPN, SREBF1, STK10, STK11, STYX, XCL2, ADAM17, CNTN2, CLEC3B, TNFRSF1A, TNFRSF1B, TPD52L1, HSP90B1, TSG101, TNFRSF4, UBE2L3, UVRAG, VEGFB, VEGFC, VRK2, EIF4H, WFS1, WNT11, FZD5, AIMP2, ARHGEF5, FGF23, CDK2AP1, FZD4, FZD7, FZD8, GFI1B, BCAR3, IKBKG, IKBKAP, CAMK1, MAPKAPK5, CDC14B, PDE5A, EIF3G, EIF3J, EIF4G3, PEA15, EED, CRADD, ADAM9, RIPK2, TNFRSF6B, TNFRSF18, NRP1, CDC123, EIF2B2, RPS6KA4, TNFSF18, DIRAS3, UNC119, AIFM1, CCNE2, ARHGEF2, VAPB, CRLF1, GPR55, S1PR2, TAOK2, AKAP6, GDF15, NRG2, TRAF4, CTR9, EIF5B, RAPGEF2, SLK, HDAC4, ATG13, IST1, RB1CC1, ZEB2, NUAK1, RBM8A, OXSR1, TNFSF15, RBX1, CASP8AP2, ABI1, PDCD6, BCL2L10, BCL2L11, TOM1L1, RAD50, FEM1B, TRAP1, AKAP9, RASA4, ATP6AP2, SORBS3, TNK2, RNF41, EIF1, EIF1B, ABCA7, RAPGEF3, ZER1, EIF3M, STK25, ARL6IP5, ARFGEF1, USP16, KHDRBS1, CTCF, NRG3, ARPP19, FRS3, RUVBL2, ARID5A, MALT1, JTB, COPS8, COPS5, IL24, ADRM1, CDC37, MAP4K5, CHEK2, FZD10, AKAP13 |
1692 | GO:0009142 | 0.02 | 1.94 | 15.33 | 22 | 41 | nucleoside triphosphate biosynthetic process | AK1, AK4, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, ATP5O, CTPS1, DTYMK, LDHC, STAT3, TYMS, SUCLG1, TBPL1, ATP5J2, SLC25A13, ATP5H, ATP5L |
1693 | GO:0009306 | 0.00 | 1.94 | 58.71 | 84 | 158 | protein secretion | ABCA1, ACVR2B, ADCY5, ADRA2A, ANGPT1, ANXA1, ANXA5, APOA1, ARL4D, ARL2, ARNTL, CACNA1A, CANX, CD36, CHRM3, CNR1, CRP, DRD3, EFNA5, EPHA5, FBLN1, GAS6, GHSR, GLP1R, GNAS, HMGCR, FOXA2, IFNA2, RBPJ, IL1RN, ITPR1, ITPR2, KCNC2, KCNJ11, KCNS3, LLGL2, LTBP2, PAM, PARK2, PDE3B, PDE4C, PIK3C3, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PTPRN, PTPRN2, RAB1A, RAB13, RAF1, REST, RFX3, S100A12, S100A13, CX3CL1, SLC2A1, SLC16A1, SNAP25, SREBF1, STXBP1, STXBP3, ABCC8, SYT5, HNF1A, TRAF2, VIP, SCG2, SYT7, HMGN3, NRXN1, EIF2AK3, ATG5, CLOCK, RIMS2, NR1H4, RAPGEF3, TNFSF13B, TRAF3IP2, CPLX1, RAPGEF4, BTN3A1 |
1694 | GO:0030029 | 0.00 | 1.94 | 62.18 | 89 | 168 | actin filament-based process | ACTG1, ACTN1, ADRA2A, ANG, ANXA1, ARHGDIB, BCL2, BCR, CASQ1, CASQ2, CDC42, CNN1, CNN3, CTNNA1, CXADR, DIAPH1, DIAPH2, DPYSL3, EMP2, EPB41, EPB41L2, FGD1, FGF7, GHSR, CXCL1, INPPL1, INSRR, ITGB1, KCNE1, KCNH2, KCNQ1, KIT, KRAS, KRT19, LLGL2, ATXN3, MYO1B, PAWR, PRKAR1A, PRKCI, PRKCZ, PTPN1, RAB13, RAC2, RAC3, RALA, RAN, RAP2A, S100A9, SCN4B, SDCBP, SELE, SHC1, SRF, TNNC2, TNNI2, TNNI3, TNNT1, TPM2, HSP90B1, CLRN1, VIM, CORO2A, CUL3, SORBS2, GAS7, DYNLL1, CFLAR, ARHGEF2, PDLIM7, S1PR2, TRIP10, TAOK2, SLC9A3R1, BCAR1, CDC42BPB, NUP155, ARHGEF11, ARHGEF17, ELMO1, FARP2, KCNE2, ABI1, CORO2B, MAD2L2, CAP1, SORBS1, CAPN10, KPTN |
1695 | GO:0010638 | 0.02 | 1.94 | 18.11 | 26 | 49 | positive regulation of organelle organization | AKT2, ANXA1, BIRC5, BBS4, CD28, DRD3, EDN3, EREG, IGF1, IGF1R, IGF2, IL1A, INS, LMAN1, CNOT2, PIP4K2A, SDCBP, FSCN1, AURKA, SURF4, SYT1, TSG101, C2CD5, PDCD6IP, SEPT9, UBE2C |
1696 | GO:0048738 | 0.00 | 1.94 | 27.25 | 39 | 73 | cardiac muscle tissue development | ACVR1, AGTR2, CAV3, COL11A1, CXADR, DSP, S1PR1, FGF3, KAT2A, ISL1, ITGB1, KCNK2, SMAD1, SMAD7, PLN, PRKAR1A, PTEN, RARA, RARB, RXRA, RYR2, SGCB, SLC9A1, SRF, TAZ, TNNC1, TNNI3, TNNT2, TP73, TSC1, CSRP3, SORBS2, HDAC3, ALDH1A2, CTDP1, HAND1, ATG5, SPEG, ATG7 |
1697 | GO:0009628 | 0.00 | 1.93 | 35.31 | 51 | 99 | response to abiotic stimulus | ATP2B1, BAG1, CAMK2A, CASQ1, CD9, CDH8, CDK2, CETN1, DCX, DHX9, EEF1A2, EIF2B1, HMGCS2, HNRNPD, HSPA6, HSPA8, HSPB2, HSP90AA1, IL1A, IMPDH1, KCNJ3, ATXN3, NUP88, NUP98, RANBP2, RPA2, RPA3, S100A13, ST8SIA1, SOD1, DNAJC7, NUP214, AAAS, SLC14A2, SNN, EIF2B3, EIF2B2, EIF2B5, EIF2AK3, BAG5, BAG4, NUP155, ZNF516, NUP93, HDAC6, PDCD6, NUP50, ARPP21, GJB6, NUPL2, PSIP1 |
1698 | GO:0000724 | 0.00 | 1.93 | 32.91 | 47 | 88 | double-strand break repair via homologous recombination | ABL1, ATM, ATR, BARD1, BRCA1, BRCA2, CDK2, CHEK1, ERCC1, ERCC4, FEN1, TONSL, PPP4C, RAD1, RAD51, RAD51C, RAD51B, RAD51D, RAD52, RFC3, RFC4, RFC5, RPA2, RPA3, SFPQ, UBB, UBE2V2, SUMO1, WHSC1, XRCC2, YY1, SHFM1, HIST1H4I, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HERC2, RNF8, EXO1, REC8, RAD50, PSMD14, RAD51AP1 |
1699 | GO:0006766 | 0.00 | 1.93 | 32.91 | 47 | 88 | vitamin metabolic process | ACACB, ACPP, AOX1, APOA1, BTD, CBR1, AKR1C4, CLPS, CTRB1, CYB5A, CYP3A4, CYP24A1, DHFR, CYB5R3, GPC4, GFI1, GIF, GPC3, HLCS, IFNG, IL1B, PTGIS, ABCD4, RBP1, RBP2, RPE65, RXRA, SDC2, SDC4, SHMT1, SHMT2, SLC2A1, SLC2A3, SNAI1, CUBN, SLC25A16, FGF23, PDXK, AKR1C3, ALDH1A2, VNN2, SLC5A6, RGN, GSTO1, SDC3, GPC6, AKR1A1 |
1700 | GO:0030510 | 0.02 | 1.93 | 16.08 | 23 | 43 | regulation of BMP signaling pathway | ABL1, ACVR2A, ACVRL1, XIAP, BMP4, BMPR2, FBN1, GATA4, GATA6, GPC3, HES1, RBPJ, ILK, ITGA3, SMAD6, SMAD7, PCSK6, PPM1A, SOX11, WNT1, CHRD, CER1, FSTL3 |
1701 | GO:0003231 | 0.01 | 1.93 | 21.69 | 31 | 58 | cardiac ventricle development | JAG1, PRDM1, COL11A1, DNM2, DSP, FZD2, GATA4, GJA5, NRG1, HIF1A, HES1, RBPJ, ISL1, KCNK2, LTBP1, SMAD6, SMAD7, RXRA, RYR2, SALL1, SCN5A, SMARCD3, SOX11, TNNC1, TNNI3, TNNT2, WHSC1, WNT11, TRIP11, HAND1, CITED2 |
1702 | GO:0043009 | 0.00 | 1.93 | 37.09 | 53 | 100 | chordate embryonic development | ACVR2A, ALX3, APAF1, BBS4, BMP4, BRCA1, RUNX2, COL1A1, COL11A1, EPHA2, EN1, EXT1, EYA1, FZD2, GNAS, ARHGAP35, HOXC11, HOXD3, HOXD9, HOXD10, HOXD11, ISL1, OPA1, PBX1, PCSK5, PFN1, PRRX1, PRKACB, RALA, RARA, SALL1, SDC4, SIX1, SOX11, ZEB1, TSC1, TSC2, TULP3, WNT1, WNT11, ZIC2, FZD6, DCHS1, CHRD, DLK1, ALDH1A2, IFT140, EIF4A3, ATP6AP2, IRX5, SEC24B, DEAF1, GLMN |
1703 | GO:0016337 | 0.03 | 1.93 | 14.61 | 21 | 40 | single organismal cell-cell adhesion | CDH3, CDH7, CDH9, CDH10, CTNNA1, CTNNA2, CTNND2, RAPGEF1, ICAM2, ICAM3, ICAM4, SHC1, SOX9, ICAM5, CRISP2, ZAN, ITGA8, SLIT2, GPA33, PDPN, BVES |
1704 | GO:0035108 | 0.00 | 1.92 | 28.05 | 40 | 75 | limb morphogenesis | ALX3, ATRX, BAX, BMP4, BMPR1A, RUNX2, DLX5, DLX6, EN1, FGF4, GJA5, GPC3, GNAQ, GNAS, HOXC10, HOXC11, HOXD9, HOXD10, HOXD11, HOXD12, IDUA, IHH, AFF3, PBX1, PCSK5, PRRX1, PSEN1, RARB, SALL1, SOX9, SOX11, TULP3, TWIST1, ZNF141, FZD6, RECK, TP63, ALDH1A2, IFT140, BCL2L11 |
1705 | GO:0098779 | 0.00 | 1.92 | 28.05 | 40 | 75 | mitophagy in response to mitochondrial depolarization | ADRB2, ANXA5, COX8A, EIF2S1, STOM, FANCC, FANCF, FCGR3B, SLC37A4, GABRA5, BLOC1S1, KCNK3, KRT15, MDH1, NTHL1, P2RX5, PARK2, PEX13, SERPINB10, SFRP4, SLC1A3, SLCO1A2, SLC22A3, SNRPD1, SNRPF, STAT2, NR2C2, ZNF189, CHAF1B, BECN1, CHST3, NUP93, ATG13, PHYHIP, IST1, FGFBP1, HDAC6, HSF2BP, CDC37, ADAMTS7 |
1706 | GO:1901565 | 0.00 | 1.92 | 63.30 | 90 | 170 | organonitrogen compound catabolic process | ABAT, ACADL, ACADSB, AGXT, ALDH9A1, AMBP, AMT, AOX1, ARG1, ASL, AUH, BCAT1, BCKDHA, BHMT, BLVRA, BLVRB, CAT, CDA, CDO1, TPP1, COMT, CRYM, CTH, CTSH, CYP3A4, DBH, DBT, ACE, DPYD, DUT, TYMP, GAD1, GAD2, GALC, GLDC, GLS, GLUD1, GLUL, GM2A, GOT1, GPT, GPX1, GSTZ1, HSD17B10, HAL, HMGCL, HNMT, HPRT1, IDE, IDO1, IVD, LIPC, LTA4H, ALDH6A1, NTHL1, OAT, OGDH, OGG1, OTC, PAH, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, ENPP2, PRKCD, QDPR, RNPEP, SHMT1, SUOX, TAT, TST, UNG, UPP1, BBOX1, DDO, PDE5A, MBD4, AASS, BCKDK, RAPGEF3, PDE10A, SDS, ADAMTS13, HIBADH |
1707 | GO:0002028 | 0.02 | 1.92 | 16.83 | 24 | 45 | regulation of sodium ion transport | ADRB2, ARF1, ATP1A1, ATP1A2, ATP1B3, FXYD2, CAV3, DNM2, DRD3, STOM, P2RX4, P2RX7, PER1, FXYD3, PRKCE, SCN4B, SCN5A, SCNN1B, SGK1, SLC9A1, SLC9A3, SLC9A3R1, SGK2, AHCYL1 |
1708 | GO:0006305 | 0.02 | 1.92 | 16.83 | 24 | 45 | DNA alkylation | ATRX, BRCA1, DNMT1, DNMT3B, GNAS, MGMT, HIST1H4I, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, FKBP6, HIST1H3F, PICK1, CTCF |
1709 | GO:0023056 | 0.03 | 1.92 | 14.53 | 21 | 41 | positive regulation of signaling | CA2, CHRNB2, CHRNB4, CX3CR1, DBI, DNM1, GFAP, OXTR, PAWR, PTN, RAB3B, SLC1A3, SLC8A3, SNAP25, SNCA, STAU1, SYT1, TNR, SYNJ1, RAMP3, BVES |
1710 | GO:0009308 | 0.00 | 1.92 | 53.48 | 76 | 143 | amine metabolic process | ABAT, ACHE, AOC2, APOA1, ARG1, ARG2, ASL, ASS1, BCHE, BHMT, CCBL1, CHAT, CHKB, CHRNB2, CKM, COMT, CPS1, DBI, ACSL3, FGF7, GAMT, GATM, GOT1, GPLD1, HPRT1, IDO1, INS, LCAT, LIPC, OAZ1, OAZ2, OTC, PARK2, PCYT1A, PDE1B, ENPP2, PRKCD, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, SMS, SNCA, SULT1A1, SULT1C2, TACR3, VCAM1, PAX8, KYNU, PSMF1, PSMD6, NR1H4, SLC25A15, PSME3, PSMD14, CEPT1, PRG3, PEMT |
1711 | GO:0002526 | 0.02 | 1.92 | 17.53 | 25 | 47 | acute inflammatory response | A2M, ACVR1, ADRA2A, BDKRB2, SERPING1, C3, C7, CD6, CD59, F3, FCER1G, B4GALT1, FFAR3, ICAM1, KLKB1, CD46, OGG1, CFP, PRCP, S100A8, SPN, TAC1, TNFSF4, VCAM1, VTN |
1712 | GO:0072331 | 0.00 | 1.92 | 29.50 | 42 | 79 | signal transduction by p53 class mediator | ATRX, BAX, BCL3, BOK, BRCA1, BRCA2, CDK2, CDKN1A, E2F2, EP300, IFI16, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, SP100, STK11, DYRK2, TP63, CRADD, PSMF1, PSMD6, PSME3, PSMD14 |
1713 | GO:0002009 | 0.01 | 1.91 | 19.61 | 28 | 53 | morphogenesis of an epithelium | JAG1, CA2, CHUK, CTSV, HBEGF, FGF3, FGF7, FGFR3, GRB2, HGF, IGF1R, IGFBP5, IL10, ITGA5, SERPINB5, RREB1, RXRA, SCNN1B, SNAI1, SOX10, ADAM17, FZD5, FOXN1, HESX1, SOCS3, KLF4, FEM1B, SEMA3A |
1714 | GO:0044707 | 0.00 | 1.91 | 513.84 | 698 | 1554 | single-multicellular organism process | A2M, AARS, ABCA1, ACTL6A, ACTN1, ADAM10, AEBP1, AGTR1, APLNR, NR0B1, AK2, AK4, AKT2, ALAS2, ALDH1A3, ALDH9A1, ALDH3A2, ALDOB, ALK, AMBN, AMELY, AMHR2, ANG, APAF1, APLP1, APLP2, APRT, AQP6, ARAF, ARCN1, ARG2, ARSE, ASS1, ASTN1, ATP5F1, ATP7B, ATR, BCL2L1, TNFRSF17, BID, BOK, ZFP36L2, BSG, BTD, KLF5, BTF3, BYSL, C1QB, CAPN5, DAGLA, CALU, CAMK2A, CAPZA1, CAPZB, CASP9, CAV2, SERPINH1, CCNE1, CCNF, CD3D, CD8A, CD9, TNFSF8, ENTPD1, ENTPD2, CD59, CD72, CDH1, CDK2, CDK4, CDKN1A, CDO1, CEBPE, CENPE, CENPF, CHD2, CHN1, TBCB, AP2S1, CLC, CLN5, CLTA, ACKR2, CNP, COL4A5, COL4A6, COL6A2, COL6A3, COL9A2, COL9A3, COL12A1, COL15A1, COL16A1, COL17A1, COX6B1, CR2, CRYBA4, CRYGB, CSNK2A1, CSNK2A2, CSRP1, CSRP2, CTF1, CTNNA2, CTSD, CTSV, CYLC1, CYLC2, DAD1, DGKA, DGKB, DGKQ, DAPK3, DAZ1, DCX, DDX1, DFNA5, DHCR24, DHFR, DIAPH2, DLG2, DLG3, DLX6, DMBT1, DNM1, DNASE1L2, DNASE2, DNM2, DNMT1, RCAN1, EPYC, ECM2, DUSP1, DUSP4, DUSP5, DYRK1A, E2F4, E4F1, EBF1, GPR183, TYMP, EDA, S1PR3, PHC1, PHC2, EFNA3, EFNA4, EIF2B1, EIF4A1, EIF4EBP1, ELAVL1, ELAVL3, EML1, EMP1, EPHA5, EPHA8, EPS8, EYA4, ERCC3, ETV6, EXTL1, EYA2, EYA3, EZH1, F2RL2, F10, FABP7, FANCA, ACSL3, ACSL4, FANCF, FANCG, FBN1, GPC4, FGD1, FGF5, FGFR4, FLI1, CENPI, FSHR, NR5A2, FZD2, GABRA4, BLOC1S1, GDF9, GFRA1, GFRA2, GGCX, GJB1, GJB5, GLRA2, GLUD1, GNA15, GNAI1, GNAQ, GNAT1, GNAT2, GNB1, GNGT1, GNRH2, GNRHR, GP9, GPM6A, GRB7, GRID2, CXCL1, GUCY1B3, HIST1H1T, HSD17B10, HBD, HBE1, HBG1, HCCS, SERPIND1, HEXB, HIC1, HIVEP2, HLF, HMBS, HMGN1, HMGCL, HMGCS1, HMX1, HMX2, HNF4G, ONECUT1, HNRNPD, HPGD, HPRT1, AGFG1, HSD11B1, HSF4, HSPA8, HSP90AA1, HSP90AB1, IDE, IDH1, IDUA, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGF1R, IL1RAP, IMPDH1, IMPDH2, ING2, INSIG1, INSL4, INSRR, IRF2, ITGA1, ITGA9, ITGAM, ITGAV, ITGAX, ITGB4, JARID2, KCNC1, KCNC2, KCNJ8, KCNJ10, KIF5A, KLC1, KRT9, KRT13, KRT19, KRT83, AFF3, LAMA3, LAMA4, LAMP2, LCAT, LDHA, LIM2, ABLIM1, LMAN1, LTA4H, LTBP1, EPCAM, SMAD9, MAL, MAP6, MARK3, MATN3, MGMT, ATXN3, DRG1, SEPT2, CNOT2, NRL, NRTN, YBX1, NTN3, NUMA1, ODF1, OGDH, OGN, OLR1, OMP, OPCML, SIX6, OTC, OVOL1, OXCT1, P2RX5, PEBP1, PAFAH1B2, PAFAH1B3, PAM, CNTN3, PAX4, PAX9, PCDH9, SERPINA5, PCNA, PCOLCE, PEPD, PEX13, PF4V1, ATP8B1, PFKFB1, PGM3, PHF2, SERPINB5, PIK3CB, PIM1, PIP4K2A, PRRX1, PPP2R5D, PPP5C, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTGDR, PTPN1, PTPN6, PTPRA, PTPRJ, PTPRN, PTPRS, RAD1, PURA, QDPR, RAB1A, RAB5A, RAB27A, RAD23B, RAD51C, RAD51B, RAF1, RALA, RAP2A, RAP2B, RASA2, RBM4, RCN1, PRPH2, RPGR, RPL22, RPL24, RPL29, RPS4X, RPS4Y1, RPS6KA1, RRM1, RS1, RYK, S100A1, S100A4, S100A6, S100A7, S100A8, S100A12, S100A13, SATB1, SDC2, SDC4, SDF2, SDHA, TRAPPC2, SELE, SELL, SELPLG, SEMG1, SRSF1, SRSF4, SRSF5, SGCA, SGCB, SHB, SIAH1, SLC1A3, SMTN, SLC6A11, SLC12A1, SLC16A1, SLIT3, SMARCA1, SMARCA2, SMARCA4, SMARCC2, SMARCD1, SMARCE1, SNCA, SNRPE, SOS1, SOS2, SOX12, SPAST, SRD5A1, SREBF1, SRPK2, TROVE2, STRN, STXBP1, STXBP3, SVIL, TACC1, TAGLN, TAZ, TBCE, HNF1A, TMOD1, TNFRSF1A, TNFRSF1B, TNNT2, TNP2, TOP2A, TOP2B, TPD52, TRO, TRPC4, TRPC5, TSC1, TSC2, TSG101, TSPY1, TUBA4A, TYMS, TYR, TYRO3, TYROBP, UGDH, UPK2, UPK3A, VAV1, VCAM1, WEE1, YWHAZ, ZFP36, ZNF3, ZNF7, ZNF22, ZNF24, ZNF45, ZNF74, ZNF141, ZNF148, ZBTB17, VEZF1, ZNF217, PRDM2, CSDE1, RNF103, AIMP2, HMGA2, SLC7A5, MADCAM1, DPF1, USP9X, SMC1A, PICALM, FZD4, FZD6, FZD8, GFI1B, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, SOX14, BCAR3, BFSP2, RECK, DOC2A, CUL3, CUL1, GAS7, DGKZ, COPS3, PIR, KLF7, CDK13, UNC5C, AKR1C3, DYNLL1, BECN1, PEA15, JRKL, DGAT1, EDF1, EED, ADAM19, ADAM15, TNFRSF6B, TNFRSF18, DLK1, TNFRSF10D, TNFRSF10B, SCEL, TNFRSF10A, CDKL1, SAP30, HESX1, LIN7A, CFLAR, PROZ, ARHGEF7, VNN2, EIF2B3, EIF2B2, EIF2B5, EIF2S2, SGCE, BSN, HIST1H3F, KALRN, RNF8, BAZ1B, DOK2, PAPSS2, PAPSS1, ATP6V0D1, INA, KRT75, SMC3, AIFM1, CCNB2, SYNGR3, DYRK1B, EXO1, FIBP, ZMYM6, AURKB, CRLF1, S1PR2, NREP, COPS2, TRIP11, GTF3C5, SLC9A3R2, SLC22A6, SLC9A3R1, RECQL4, QKI, PICK1, CHST3, ONECUT2, PSMF1, SLC4A7, ADAMTS4, ADAMTS3, ADAMTS2, GAL3ST1, LITAF, BAG3, NRG2, APBA3, CXCL14, SOX13, ABCG1, KLK4, GNA14, FEZ2, ZNF516, TRAM2, ADAMTSL2, SNPH, RAPGEF5, SNX17, MAML1, SPOCK2, KEAP1, RB1CC1, SPATA2, ARHGEF11, GINS1, ZBTB24, GAB2, FARP2, PSMD6, TRIL, SETDB1, RBX1, DOPEY2, REC8, SLC12A6, NR2E3, SH2B3, RANBP9, ABCB6, COX17, GPC6, COL4A3BP, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN2, ARPC2, ARFRP1, RASA4, FARP1, WASF2, ZNF256, RNF41, PSME3, DHRS2, PSMD14, ABCC4, IRX5, SIGMAR1, SPEG, CNPY2, ARIH2, SEC24B, FAM3C, VAV3, TACC3, TRIM38, SLC9A6, CAP1, CHERP, ARPC1A, ARFGEF1, SLC34A2, DPYSL4, TACC2, SH2B2, HEXIM1, TXNIP, PDPN, IGF2BP3, EBP, FUT9, STAG2, RAI2, CHL1, VAMP5, GJB6, CPLX2, FRS3, PDE10A, ARID5A, RAB10, EDAR, PRDX3, TMED2, YWHAQ, SLC27A4, KIF2C, RAB35, WWP1, RAPGEF4, KERA, ESM1, ADAMTS13, BTN3A1, KIF3A, SLC7A9, BVES, SOX21, FZD10, SEC63, HPS5 |
1715 | GO:0009144 | 0.00 | 1.91 | 42.26 | 60 | 113 | purine nucleoside triphosphate metabolic process | AK1, AK2, AK4, ALDOB, ALDOC, AMPD2, ARNT, ATP1A2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V0A1, ATP5O, BAD, TSPO, COX4I1, COX8A, COX15, CTNS, ENO2, ENO3, GAPDH, GPD1, HIF1A, HSPA8, IGF1, INS, LDHA, LDHC, OGDH, P2RX7, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PGM1, PPP2R5D, PRKAA1, PRKAG1, SDHC, SNCA, STAT3, TAZ, UQCRC1, UQCRC2, UQCRH, OGT, ATP5J2, HDAC4, SLC25A13, ATP5H, ATP5L |
1716 | GO:0031497 | 0.00 | 1.91 | 30.29 | 43 | 81 | chromatin assembly | ATRX, CDKN2A, CENPA, CENPI, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, HIST1H1A, HMGA1, SET, SOX9, TSPY1, HMGA2, CHAF1B, HIST1H4I, HIST1H2BG, HIST1H2BL, HIST1H2BN, HIST1H2BM, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, HAT1, RUVBL1, HIST1H3F, HIST1H2BJ, H1FX, CTCF |
1717 | GO:0010647 | 0.02 | 1.90 | 18.08 | 26 | 51 | positive regulation of cell communication | BNIP3L, CA2, CHRNB2, CHRNB4, CX3CR1, DBI, DNM1, GFAP, GJA5, OXTR, PAFAH1B2, PAWR, PIP4K2A, PTN, RAB3B, SLC1A3, SLC8A3, SNAP25, SNCA, STAU1, SYT1, TNR, EPM2A, SYNJ1, ATG5, ATG7 |
1718 | GO:0072330 | 0.00 | 1.90 | 38.10 | 54 | 102 | monocarboxylic acid biosynthetic process | ABAT, ACACB, ACADL, ACADM, ACADVL, ACLY, AGXT, ALDH1A3, ALDH9A1, ALOX12, ALOX15B, ANXA1, APOA1, AVP, BRCA1, CBR1, VCAN, CSPG4, DCN, ACSL3, GAD1, GGT7, HPGD, IDO1, INSIG1, LDHC, LIPC, FADS3, LTA4H, PDK4, PRKAA1, PRKAG1, PTGIS, PTGS1, ABCD3, RBP1, RNPEP, ACSM3, SHMT1, SLC1A3, STK11, NR1H2, BBOX1, AKR1C3, ALDH1A2, RGN, FADS2, QKI, DHRS9, PRG3, ERLIN1, FAXDC2, SDS, ERLIN2 |
1719 | GO:0071103 | 0.00 | 1.90 | 51.61 | 73 | 138 | DNA conformation change | ANXA1, ATRX, CCNB1, CDKN2A, CENPA, CHD1, CHD2, CHD3, CHD4, DDX1, DHX9, ERCC3, CENPI, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, HIST1H1A, HHEX, HMGA1, CHMP1A, PURA, RAD51, SET, SOX9, SUPV3L1, TOP1, TOP2A, TOP2B, TSPY1, XRCC5, HMGA2, CHAF1B, HIST1H4I, HIST1H2BG, HIST1H2BL, HIST1H2BN, HIST1H2BM, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, HAT1, RUVBL1, HIST1H3F, HIST1H2BJ, H1FX, AIFM1, RECQL5, RECQL4, CHD1L, GINS1, SMC4, RAD50, G3BP1, ERN2, CTCF, RUVBL2, ASCC3, PAPD7 |
1720 | GO:0001822 | 0.00 | 1.90 | 52.31 | 74 | 140 | kidney development | ACVR2B, JAG1, AGTR1, AGTR2, ALDH9A1, ARG2, ASS1, BAX, BCL2, BMP6, CA2, CAT, CD44, CENPF, COL4A3, CTSH, DCN, ACE, EDNRA, EPHA7, EYA1, FBN1, GPC3, HMGCS2, HOXC11, HOXD11, ILK, ITGA3, KCNJ1, KCNJ8, LAMA5, TACSTD2, EPCAM, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, CITED1, OVOL1, PBX1, PCSK5, SERPINF1, PRKX, PSPN, RARA, RARB, SALL1, SDC4, SIX1, SLC12A1, SLC34A1, SOX9, SOX11, STAT1, TP73, TSC1, UPK3A, WFS1, WNT1, WNT11, WNT2B, PAX8, ITGA8, DCHS1, ALDH1A2, RGN, CRLF1, CER1, SLIT2, ADAMTS1, BCL2L11, SPRY1, FSTL3 |
1721 | GO:0031398 | 0.00 | 1.90 | 45.25 | 64 | 121 | positive regulation of protein ubiquitination | ADRB2, ANGPT1, BIRC2, BIRC3, XIAP, AVPR2, BMI1, BRCA1, CAV3, CCNB1, CDC20, CDC27, CDK9, CLU, PTK2B, FGFR3, DNAJB2, SMAD7, PARK2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, SKP1, SUMO3, UBB, UBE2L3, UBE3A, WFS1, AIMP2, CUL1, CDC14B, CDC23, RIPK2, CDC16, PSMF1, CTR9, RNF40, PSMD6, PSME3, PSMD14, ANAPC10, MALT1, UBE2C |
1722 | GO:1901988 | 0.00 | 1.90 | 45.25 | 64 | 121 | negative regulation of cell cycle phase transition | ATM, CCND1, BCL2, BUB1B, CCNB1, CDC5L, CDC20, CDC27, CDK2, CDKN1A, CENPF, CSNK2A1, CSNK2A2, DUSP1, PRMT2, FOXO4, OVOL1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, RB1, RPA2, SMARCA4, SOX11, TP73, TTK, UBB, ZNF207, HMGA2, DGKZ, TP63, CDC23, CRADD, CDC16, ZW10, PSMF1, PSMD6, PSME3, PSMD14, CTDSPL, ANAPC10, MAD2L2, UBE2C, CHEK2 |
1723 | GO:0050866 | 0.00 | 1.89 | 31.79 | 45 | 85 | negative regulation of cell activation | ABAT, ADRB2, ALOX12, ANXA1, ATM, AXL, BCR, PRDM1, BMP4, BPI, CBLB, CD37, CDKN2A, CNR1, CNR2, CTLA4, CYLD, ERBB2, F2, FLT3, HLX, IFNA2, IHH, IL2RA, IL10, IL13RA2, IDO1, INHA, IRF1, PAWR, PRKAR1A, PRKCD, PTPN6, XCL1, SFTPD, SOX11, SPN, TNFAIP3, TNFSF4, TYRO3, SCGB1A1, PDE5A, TNFSF18, SOCS6, GLMN |
1724 | GO:0000075 | 0.00 | 1.89 | 60.22 | 85 | 161 | cell cycle checkpoint | BIRC5, ATM, ATR, CCND1, BCL2L1, BRCA1, BUB1B, CCNB1, CCNG2, CDC5L, CDC20, CDC27, CDK2, CDKN1A, CENPF, CHEK1, ATF2, CRY1, CSNK2A1, CSNK2A2, DUSP1, FANCG, FOXO4, PRCC, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, RAD1, RB1, RPA2, RPL24, SETMAR, SOX11, TOP2A, TOP2B, TP73, TTK, UBB, XPC, ZNF207, HMGA2, SMC1A, CUL4A, DGKZ, CDC14B, TP63, PEA15, CDC23, CRADD, CDC16, CCNE2, ZW10, AURKB, TAOK2, PSMF1, CLOCK, MAD2L1BP, PSMD6, FEM1B, PSME3, PSMD14, ANAPC10, MAD2L2, UBE2C, ZWINT, CHEK2 |
1725 | GO:0051607 | 0.00 | 1.89 | 27.52 | 39 | 74 | defense response to virus | ADAR, ADARB1, BCL2, BNIP3, BNIP3L, BST2, CD8A, CD86, CXADR, DMBT1, F2RL1, GBP3, IFI16, IFIT3, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, ILF3, IRF1, IRF5, ISG20, KCNJ8, OAS2, OAS3, STAT1, TRIM25, BECN1, ABCC9, TRIM22, IFITM3, SPON2, ATG7, IFITM2, SERINC3, IFI44L |
1726 | GO:0048522 | 0.01 | 1.89 | 23.25 | 34 | 72 | positive regulation of cellular process | ACHE, ATP1B3, CASP5, CD58, DPP6, GLRA1, FFAR3, KCNC1, KCNC2, KCNE1, KCNH2, KCNJ2, KCNJ11, KCNQ1, ATXN3, PAEP, SEPT5, RAB5A, RAB27B, S100A1, SLC34A1, SLC18A1, STC1, STXBP1, SLC30A2, PIK3R3, USP13, SYT7, RAB9A, AKAP7, STXBP5L, RAB3D, KCNE3, SEC24A |
1727 | GO:0048525 | 0.02 | 1.89 | 19.07 | 27 | 51 | negative regulation of viral process | ADAR, APCS, BST2, FBLN1, IFI16, IFIT1, IFNA2, ILF3, ISG20, JUN, LTF, OAS3, PARK2, EIF2AK2, REST, SLPI, SP100, SRPK2, TRIM21, STAT1, TRIM25, HMGA2, VAPB, TRIM13, TNIP1, IFITM3, IFITM2 |
1728 | GO:0043124 | 0.05 | 1.89 | 12.72 | 18 | 34 | negative regulation of I-kappaB kinase/NF-kappaB signaling | ABL1, CYLD, ESR1, IL10, PER1, PPM1A, PPM1B, STAT1, TNFAIP3, TRIP6, RIPK1, TNFSF14, IL1RL1, LITAF, NR1H4, TNIP1, OLFM4, ZMYND11 |
1729 | GO:0060078 | 0.05 | 1.89 | 12.72 | 18 | 34 | regulation of postsynaptic membrane potential | ABAT, ADRB2, PTK2B, GLRA1, GRID2, GRIN2A, NTSR1, P2RX4, PRKCZ, RELN, PTEN, CX3CL1, SNCA, DGKI, S1PR2, NRXN1, RIMS2, EIF4A3 |
1730 | GO:0060291 | 0.05 | 1.89 | 12.72 | 18 | 34 | long-term synaptic potentiation | CREB1, CRH, CX3CR1, DBI, PTK2B, GFAP, GRIN2A, NTRK2, PRKCZ, RELN, PTEN, PTN, S100B, SLC8A3, SNAP25, SNCA, STAU1, TNR |
1731 | GO:1901983 | 0.05 | 1.89 | 12.72 | 18 | 34 | regulation of protein acetylation | BRCA1, CHEK1, KAT2A, IL1B, ISL1, SET, SNCA, TAF7, TWIST1, CAMK1, KAT2B, RPS6KA4, ATG5, RAPGEF3, ATG7, CTCF, RUVBL2, ARID5A |
1732 | GO:2000278 | 0.05 | 1.89 | 12.72 | 18 | 34 | regulation of DNA biosynthetic process | ACVRL1, BMPR2, CDKN1A, DKC1, DUSP1, PTK2B, FGFR4, HGF, KCNK2, NVL, PRKCQ, MAPKAPK5, RGN, AURKB, KLF4, CCT4, CCT2, CERS1 |
1733 | GO:0051130 | 0.00 | 1.89 | 51.48 | 73 | 141 | positive regulation of cellular component organization | AHSG, ANGPT1, AXL, ADGRB1, ADGRB2, BCR, BICD1, C3, CBL, CD53, CD63, CDC20, CLU, COL1A1, COL16A1, CYBA, DAB2, EPHA2, EIF5A, STOM, EPHB1, EPHB2, EPHB3, ERBB2, ACSL3, FCER1G, FGA, FGG, FLT3LG, GAS6, GPC3, GPX1, HIP1, HRG, IFNG, ITGAV, OXTR, SERPINE1, PRKCD, PTPRJ, RAB27A, RAC3, RAP1GAP, SERPINB3, SELE, SFRP4, SFTPD, SLC11A1, SLN, SNAI1, SNCA, SOX9, TPBG, TSC1, TUB, TULP1, NR1H2, VTN, PAX8, TNFSF14, ADAM9, SYNJ1, NRXN3, NRXN1, GDF15, FRMPD4, TSPAN1, RAMP3, ABCA7, ATP8A1, OLFM4, SORBS1, RER1 |
1734 | GO:0048732 | 0.02 | 1.88 | 16.90 | 24 | 46 | gland development | AKT2, APRT, ATP2B2, ATP7B, BRCA2, CDO1, CHUK, GPX1, NRG1, HIF1A, HOXD3, HOXD9, HRH2, IGF2, MGMT, OXTR, PAM, RAP1GAP, RREB1, SOX10, WNT2, PAX8, EIF2AK3, DEAF1 |
1735 | GO:0030041 | 0.04 | 1.88 | 13.43 | 19 | 36 | actin filament polymerization | ADD1, ANG, ARHGAP6, BBS4, CAPG, CAPZA1, CAPZB, DIAPH1, DIAPH2, EPS8, HCLS1, PRKCD, RDX, TMOD1, GAS7, LATS1, SLIT2, ARFGEF1, AVIL |
1736 | GO:0035295 | 0.00 | 1.88 | 99.04 | 139 | 266 | tube development | ACVR1, ACVRL1, ADM, JAG1, AGTR2, APAF1, AREG, ARG1, ARG2, ATRX, BAX, BBS4, BMPR1A, BMPR2, CAT, CAV3, CD44, CDC42, CREB1, CRH, CSF1R, CTGF, CTSH, CTSZ, DHCR7, EDA, EDNRA, EPHA2, EIF4E, EIF4EBP1, EN1, EP300, EPHA7, ESR1, ETV4, ETV5, EYA1, FGF3, FGF7, FZD2, KAT2A, B4GALT1, GJA5, GPC3, ARHGAP35, HHEX, FOXA2, HOXD11, HSD11B1, IGF1, IGFBP5, RBPJ, IL13, ILK, ING2, ITGA3, KDR, KRAS, LAMA5, LTA4H, TACSTD2, EPCAM, SMAD1, SMAD6, SMAD7, SMAD9, CITED1, NUMA1, OPA1, PAX3, PBX1, PFN1, PGR, PRKACB, PRKX, PSPN, PSEN1, PTHLH, PTN, RALA, RARA, RYR2, SDC4, SRSF6, SFTPD, STIL, SIM2, SIX1, SLC12A2, SOX2, SOX9, SP1, SPARC, SPINT1, SREBF1, SRF, ST14, STAT1, ZEB1, TSC1, TSC2, TULP3, TWIST1, UBB, KDM6A, WNT1, WNT2, WNT2B, ZIC2, PAX8, AIMP2, FZD6, CHRD, NUMB, NRP1, SEMA5A, CRLF1, ITGB1BP1, CER1, SLIT2, HAND1, ADAMTS2, TRAF4, ADAMTSL2, SEMA3E, IFT140, ZEB2, REC8, BCL2L11, ATP6AP2, SPRY1, FSTL3, KLF2, CITED2, SEC24B, DEAF1, PDPN, EDAR, GLMN |
1737 | GO:0007417 | 0.01 | 1.88 | 21.81 | 31 | 60 | central nervous system development | ALDH3A2, BTD, TPP1, VCAN, RCAN1, F2, GABRA4, GFAP, HMBS, IL1B, JARID2, MAL, NRCAM, NTRK3, PAM, PARK2, PCP4, PSPN, S100A8, S100A9, S100B, SEMA3F, SIX1, STAT3, ZEB1, VIM, RNF103, PAX8, JRKL, VNN2, WWP1 |
1738 | GO:0098771 | 0.00 | 1.88 | 48.10 | 68 | 131 | inorganic ion homeostasis | ABCB7, ACO1, AGTR2, ALAS2, XIAP, APLP2, ARF1, ATP1A1, ATP1A3, ATP12A, ATP1A4, ATP1B3, ATP4A, ATP6V1A, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, AVPR2, BMP6, CA2, CFTR, CLCN3, CLN5, COMT, FGFR4, FTL, HIF1A, HPX, KCNH2, KCNJ2, KCNJ10, LTF, NUBP1, SLC11A2, OTC, PDK4, PTGER4, RHAG, SCN7A, SCNN1A, SCNN1B, SCNN1G, SCO1, SFRP4, SGK1, SLC9A1, SLC9A2, SLC9A3, SLC9A5, SLC34A1, SOD1, UPK3A, RAB7A, FGF23, PICALM, ATP6V0D1, SLC9A3R1, ABCG2, ATP6V1G1, HEPH, ABCB6, SGK2, SLC9A6, SLC34A2, CORIN, SLC26A1 |
1739 | GO:0033365 | 0.00 | 1.88 | 195.98 | 272 | 524 | protein localization to organelle | ACTL6A, ADAR, AGTR2, ANGPT1, ARF6, ARL1, ARL2, ARNTL, ASNA1, RERE, ATR, ATRX, BAD, BAX, BBS1, BBS2, BBS4, BCL2, BCL3, BICD1, BID, BMP4, BMP6, BMPR1A, BNIP3L, BRCA1, BRCA2, BUB1B, TSPO, CBLB, CCT6A, CD36, SCARB2, CD81, CDH1, CDKN1A, CDKN2A, CENPA, COL1A1, CSE1L, CSNK1D, CSNK2A2, CTSK, CYLD, DAB2, DDX1, DHX9, DIAPH1, DKC1, EDA, F2R, FAU, NR5A1, FYB, FYN, GAS6, KAT2A, GFER, GNAQ, GOLGA4, SFN, GPR26, HIST1H1B, HCLS1, NRG1, HHEX, HNMT, HES1, HSPA4, HSPA8, HSPA9, HSP90AA1, HSP90AB1, IFNG, IGF1, IL1B, IL10, IL12B, IL18, INS, ITGAX, JUN, KPNA1, KPNA2, KPNA3, KPNA4, KPNA5, TNPO1, IPO5, SMAD3, RPL10A, TONSL, YBX1, NUP88, NUP98, OGG1, OR1D2, PRDX1, PARK2, PCM1, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX14, PPM1A, PPM1B, PPP3R1, PRKCD, PRKCQ, MAPK8, PEX19, PEX5, RAB6A, RAC2, RAD21, RAN, RANBP2, RB1, RDX, RNASE2, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, RYR2, SFRP5, STIL, SIX1, SIX3, SLC9A1, SLC11A1, SUMO3, SOX9, SREBF1, SRP9, SRP14, SRP19, SRP68, SSR1, STAT3, AURKA, STK11, TNFAIP3, CCT3, TRIP6, TSC2, TUB, TULP1, TULP2, TULP3, U2AF1, UBE2L3, SUMO1, WRB, YWHAZ, ZIC1, ZBTB17, FZD5, RAB7A, NUP214, CSRP3, AKAP1, UBL4A, BAP1, FZD7, DYRK2, OGT, AP3B1, RGS20, RUVBL1, AKR1C3, DYNLL1, BECN1, TNFSF14, RAB11A, NRP1, HDAC3, AP3D1, CDKL2, SEMA5A, RPL14, ZW10, AURKB, TRIP11, RPL23, SLC9A3R1, ZFYVE9, PEX16, CRIPT, EIF2AK3, AKAP6, LITAF, BAG4, NUP155, IPO13, NUP93, CROCC, IFT140, ZFYVE16, ATG13, TOMM20, KEAP1, KIAA0753, KLHL21, SUPT7L, FAM20B, BCL2L11, SAE1, ARFRP1, NUTF2, APC2, ABCA7, PEMT, ARIH2, TACC3, CREB3, CHERP, CCT7, CCT4, CCT2, RBCK1, TXNIP, RUVBL2, RAB10, EDAR, AFG3L2, KDELR1, SEC61B, TOMM34, OS9, YWHAQ, KDELR2, KDELR3, RAB35, KAT7, RPL35, SEC63 |
1740 | GO:0042110 | 0.03 | 1.88 | 16.25 | 23 | 44 | T cell activation | ABL2, BCL2, ZFP36L2, RUNX2, CD7, CD8A, CD8B, TNFSF8, CDK6, CXADR, FLT3, INS, KIT, SMAD3, RAG2, RPL22, SRF, STK11, ADAM17, WNT1, FZD5, FZD7, FZD8 |
1741 | GO:0046785 | 0.04 | 1.88 | 13.46 | 19 | 36 | microtubule polymerization | ABL1, ARL2, CAV3, CSNK1D, GOLGA2, RGS2, RPS3, CLIP1, SGK1, SNCA, TBCD, TUBG1, ZNF207, RANBP9, AKAP9, TUBGCP3, TUBGCP2, STMN2, TPPP |
1742 | GO:0055001 | 0.01 | 1.88 | 27.68 | 39 | 74 | muscle cell development | ACTG1, ADM, AGTR2, BCL2, BMP4, CACNB4, CASQ1, CASQ2, CAV2, CAV3, CCNB1, CFL2, CXADR, FLNC, GATA4, GPX1, HES1, IGF1, ITGB1, KRT19, PRKAR1A, RYR1, SGCB, SRF, TMOD1, TNNT2, CSRP3, SORBS2, CFLAR, CTDP1, AKAP6, ATG5, HDAC4, MAML1, RAMP2, SPEG, ATG7, AFG3L2, BVES |
1743 | GO:0001843 | 0.01 | 1.87 | 20.57 | 29 | 55 | neural tube closure | ADM, APAF1, BBS4, BMP4, FZD2, KAT2A, ARHGAP35, OPA1, PAX3, PFN1, PRKACB, RALA, RARA, SALL1, SDC4, STIL, SPINT1, ST14, TSC1, TSC2, TULP3, TWIST1, KDM6A, ZIC2, FZD6, ZEB2, SEC24B, DEAF1, GLMN |
1744 | GO:0060070 | 0.03 | 1.87 | 14.87 | 21 | 40 | canonical Wnt signaling pathway | CCND1, CDC42, CDH3, CTNND2, GATA4, MGAT3, CDK14, PSEN1, PTEN, RAB5A, RYK, RYR2, STK11, TBL1X, KDM6A, FZD4, FZD7, FZD8, FZD9, KLF4, FZD10 |
1745 | GO:0043901 | 0.04 | 1.87 | 14.18 | 20 | 38 | negative regulation of multi-organism process | ARHGDIB, PRDM1, CD36, IFNG, IGF1, IL2RA, IL10, IL12B, ITGAV, OVGP1, PCBP2, PPM1B, SEC14L1, TNFAIP3, ZP2, TPST2, TRIB1, TRIM38, PRDX4, SPINK5 |
1746 | GO:0043436 | 0.00 | 1.87 | 29.61 | 42 | 82 | oxoacid metabolic process | ANGPT1, BNIP2, EXT1, EXT2, EXTL1, EXTL3, GPC4, GALNS, B4GALT1, GPC3, GLB1, HEXA, HEXB, IDS, LUM, CHST6, OMD, OGN, SDC2, SDC4, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, B4GALT4, B4GALT3, PAPSS2, PAPSS1, B4GALT6, B4GALT5, CHST3, MINPP1, SDC3, SPOCK2, HS3ST4, HS3ST3B1, GPC6, B3GNT3, SLC26A1, SLC35D2, KERA |
1747 | GO:0030099 | 0.03 | 1.87 | 15.59 | 22 | 42 | myeloid cell differentiation | ACTN1, ADAR, ADD1, ALAS2, CASP9, CBFB, DNASE2, EP300, FLI1, GFI1, SLC11A2, PIP4K2A, PRKX, PTPN6, RHAG, RPS19, SP1, SRF, ABI1, WASF2, KLF2, PRDX3 |
1748 | GO:0043488 | 0.00 | 1.87 | 29.14 | 41 | 78 | regulation of mRNA stability | ZFP36L2, EIF4G1, HSPA8, HSPB1, TNPO1, PRKCD, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, UPF1, SET, UBB, SCGB1A1, YWHAZ, NUP214, ANP32A, KHSRP, QKI, PSMF1, PSMD6, PSME3, PSMD14 |
1749 | GO:0017015 | 0.04 | 1.87 | 14.19 | 20 | 38 | regulation of transforming growth factor beta receptor signaling pathway | CAV2, CAV3, DNM2, FBN1, ONECUT1, ITGA3, LTBP1, SMAD3, SMAD6, SMAD7, PPM1A, SOX11, ZEB1, UBB, WNT1, NREP, ZFYVE9, ONECUT2, ADAMTSL2, STRAP |
1750 | GO:0045944 | 0.00 | 1.87 | 183.83 | 255 | 493 | positive regulation of transcription from RNA polymerase II promoter | ACVR1, ACVR2A, ACVRL1, ADRB2, JAG1, AKT2, APP, PHOX2A, ARNT, ARNTL, ASCL1, RERE, ATOH1, ATRX, BACH1, BCL3, BMP3, BMP4, BMP6, BMPR1A, BMPR2, BRCA1, KLF5, CBFB, CCNC, CCNH, CCNT1, CCNT2, CD3D, CD28, TNFSF8, CD81, CDK8, CDK9, CDKN2A, CDX1, CDX4, CEBPE, CGA, CHUK, ATF2, CRX, DCN, DDIT3, DDX5, DRD3, ARID3A, E2F4, EBF1, S1PR1, EGR2, ELK1, EN1, ERCC3, ESR1, ESRRG, ETS1, ETV4, ETV5, ETV6, EVX1, EYA1, EZH1, F2RL1, FGF4, FLI1, FSHB, NR5A2, NR5A1, GABPA, GALR1, GATA4, GATA6, GCG, KAT2A, NR6A1, GTF2F1, H2AFZ, HCLS1, HEXB, HGF, NRG1, HHEX, HMGA1, NR4A1, ONECUT1, HOXC11, HOXD8, HOXD9, HOXD10, HES1, HSF4, IFI16, IFNG, IGBP1, IGF1, IGF2, IHH, IL1A, IL1B, IL10, IL17A, INSIG1, IRF1, IRF2, IRF5, ISL1, JUN, JUND, ABLIM1, LMO1, LUM, EPCAM, SMAD3, SMAD7, MEOX2, CIITA, FOXO4, CITED1, PPP1R12A, NRL, YBX1, NTF3, SIX6, OTX1, OTX2, P2RY1, SERPINE1, PARK2, PAX3, PAX9, PBX1, PCK1, PER1, PF4, PGR, PRRX1, PPP3R1, PRKD1, RAD21, RAF1, RARA, RARB, RB1, RBL1, RELB, REST, RFX3, RLF, RPS6KA1, SALL1, SIX1, SIX3, SLC9A1, SLC11A1, SMARCA2, SMARCA4, SOX1, SOX2, SOX9, SOX10, SOX11, SOX12, SP1, SREBF1, STAT1, STAT3, STAT4, STAT5B, STAT6, SUPT4H1, TAF2, TAF7, TAL1, TBL1X, ZEB1, TNFRSF1A, TOP2A, TP73, NR2C2, TSC2, TWIST1, UBB, UBE3A, UCN, NR1H2, WNT1, WNT2, YY1, ZIC1, CNBP, ZSCAN21, ZNF148, PAX8, FZD5, CSRP3, FOSL1, HMGA2, NRIP1, FZD8, OGT, ITGA8, IKBKG, CAMK1, STK16, RFXANK, TP63, RIPK1, RIPK2, HDAC3, KAT2B, BUD31, PHOX2B, RPS6KA4, CBFA2T2, ARHGEF2, CCPG1, ITGB1BP1, KLF4, HMGN3, HAND1, EIF2AK3, FHL5, ONECUT2, CLOCK, CTR9, HDAC4, MAML1, ZEB2, RNF10, NR1I3, NR1H4, NR2E3, FSTL3, TNIP1, KLF2, CITED2, RAPGEF3, RBM14, SLC30A9, USP16, ERLIN1, RBCK1, ARID3B, DMRT2, CTCF, TBR1, STAG2, RAI1, RUVBL2, ARID5A, COPS5, WWP2, ERLIN2, PSIP1 |
1751 | GO:0060341 | 0.00 | 1.87 | 128.01 | 179 | 349 | regulation of cellular localization | ABCA2, ACTL6A, AKT2, ARF6, ATP1A2, BARD1, BAX, BCL2, BCL2L1, BCL3, BID, BMP4, BMPR1A, BNIP3L, BRCA1, BST2, CALM1, CALM3, CAMK4, CASQ1, CASQ2, CAV3, CCNB1, CCT6A, CD4, CD36, CDC42, CDH1, CDH3, CDKN1A, CDKN2A, CHRM1, CSNK2A2, CTSK, CYBA, CYLD, DAB2, DIAPH1, DKC1, DNM1, EDA, EDNRA, EPHA2, STOM, ERBB2, F2, ACSL3, PTK2B, FYN, GAS1, KAT2A, GDI1, GNAQ, SFN, GPR26, GSTM2, HCLS1, NRG1, HNMT, HRC, HES1, HSP90AB1, IL12B, IL18, INSIG1, ITGA3, ITGAX, ITGB1, KCNE1, KPNA1, IPO5, SMAD3, PPP1R12A, TONSL, OAZ1, OAZ2, OGG1, P2RX3, P2RX4, P2RX5, PRDX1, PCM1, PDE4D, PLN, PPM1A, PPM1B, PPP3R1, PRKCD, PRKCI, PRKD1, MAPK8, PTEN, PTN, PTPN1, PTPN6, RANGAP1, RB1, RBM4, RDX, RNASE2, RYR2, XCL1, SFRP5, SLC9A1, SP100, STK11, TNNC1, TNNT2, CCT3, TRIP6, TRPC1, TRPC3, U2AF1, UBE2L3, VIL1, YWHAZ, ZIC1, ZBTB17, FZD5, AAAS, AKAP1, BAP1, FZD7, DYRK2, OGT, CAMK1, RGS20, RUVBL1, NUMB, DYNLL1, BECN1, TNFSF14, INPP4B, HDAC3, SYNJ1, CDKL2, SEMA5A, ITGB1BP1, SLC9A3R1, CRIPT, GSTO1, EIF2AK3, AKAP6, LITAF, GOSR1, TMEM59, BAG4, ATG13, KEAP1, C2CD5, FAM20B, BCL2L11, SAE1, NUTF2, RAMP3, APC2, TRDN, PEMT, ARIH2, SEC24B, ACAA2, TACC3, CREB3, CHERP, SIVA1, CCT7, CCT4, CCT2, SORBS1, RBCK1, KHDRBS1, EDAR, OS9, YWHAQ, RER1, KAT7, BVES, CORO1A, NUDT4 |
1752 | GO:0009790 | 0.00 | 1.87 | 54.68 | 77 | 149 | embryo development | ACVRL1, ADAM10, ADAR, ADD1, ANGPT1, ATM, BCL2L1, BRCA1, BRCA2, BTF3, BYSL, CCNB1, COL1A1, DAD1, DDX5, DMBT1, EDNRA, EFNB1, EMX1, EP300, EVX1, ACSL4, NR5A2, FUT8, GABPA, GRN, NRG1, HOXD8, INSL3, ISL1, SMAD6, MEOX2, CNOT2, YBX1, P2RY2, PCSK6, PIK3CB, PSMC3, PSMC4, PTK2, PTPRR, RAD51B, RCN1, RXRA, SEMA3F, SRSF1, SIM2, SOX10, TOP1, TOP2A, XRCC2, FOSL1, USP9X, CUL4A, COPS3, RGS20, DCHS1, DLK1, SCEL, EIF2S2, CCNB2, SLIT2, PICK1, APBA3, IFT140, KEAP1, GINS1, SETDB1, ABI1, FRAT1, COL4A3BP, ATP6AP2, SPEG, KLF2, SEMA3A, SLC34A2, RAI2 |
1753 | GO:0030279 | 0.04 | 1.86 | 14.21 | 20 | 38 | negative regulation of ossification | ADRB2, AHSG, AREG, BCL2, CDK6, ECM1, PTK2B, HIF1A, IGFBP5, RBPJ, SMAD3, CITED1, P2RY2, SOX2, SOX9, TWIST1, FGF23, CHRD, HDAC4, SEMA4D |
1754 | GO:0009267 | 0.01 | 1.86 | 22.05 | 31 | 59 | cellular response to starvation | ALB, ATF4, BCL2, BMPR2, CDKN1A, COMT, CTSV, DSC2, EIF2S1, GAS6, GLUL, HSPA8, IFI16, JUN, PCK1, PDK4, PIK3C3, PRKAA1, EIF2AK2, SLC2A1, SRD5A1, SREBF1, KLF10, UPP1, WNT2B, PPM1D, AKR1C3, EIF2AK3, PICK1, GAS2L1, RRAGA |
1755 | GO:0018193 | 0.00 | 1.86 | 279.01 | 383 | 746 | peptidyl-amino acid modification | ABL1, ABL2, ACTL6A, ACVR1, ADH5, ADRA2A, AKT2, ALK, ANGPT1, BIRC5, APLP2, APOA1, APP, ARAF, ARCN1, AREG, ARNT, ATM, ATR, AVP, AXL, BAX, BCL2, BCR, BDKRB2, BGLAP, BLK, BMI1, BRCA1, BRCA2, BTK, CALM1, CALM3, CAMK4, CAMK2A, CANX, CCK, CCNB1, CD3E, CD4, CD80, CD36, CD44, CD59, CD81, CDC42, CDK2, CDKN2A, CGA, CHEK1, CLK1, CLK3, CNTF, COPA, ATF2, CREBL2, CSF1R, CSNK1D, CSNK1G2, CSNK1G3, CSPG4, CTF1, CTH, CTSZ, DAD1, DCN, ACE, DCX, DYNC1H1, DYNC1I1, DYNC1I2, DNMT1, DNMT3B, DPAGT1, DYRK1A, PHC1, PHC2, EEF2, EFNA1, EFNA5, EGR2, EPHA2, EIF5A, EP300, EPHA1, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, ERBB2, EREG, ERCC6, ERN1, EYA1, EZH1, F2, F2R, F7, F10, PTK2B, EFEMP1, FGF7, FGFR3, FGFR4, FGR, FKBP3, FKBP5, FLT1, FLT3, FLT4, FRK, FUT8, FYN, GALNT1, GAPDH, GAS6, GCG, BLOC1S1, KAT2A, GFI1, GFRA2, GGCX, B4GALT1, GLB1, GMDS, GOLGA2, GOLGB1, GRIA1, HIST1H1B, HCK, HCLS1, HGF, NRG1, UBE2K, HMBS, HNRNPC, HPX, HRC, HRG, PRMT2, HES1, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF1R, IGF2, IL1B, IL12B, IL12RB2, IL13, IL15, IL18, ILK, INS, INSRR, ISL1, ITGA5, ITGB1, JARID2, KDR, KIT, LMAN1, SMAD7, MGAT2, MGAT3, KITLG, MAP3K11, NTF3, NTRK1, NTRK2, NTRK3, NUP88, NUP98, P4HA1, PCNA, PDE4D, ENPP2, PER1, PFN2, PGM3, PPIB, PPID, PPP2R1A, PPP6C, PRKAA1, PRKCD, PRKCE, PRKCI, PRKD1, PRKCQ, PRKCSH, PRKCZ, MAPK8, EIF2AK2, PRKX, PROC, RELN, PSEN1, PTGER4, PTK2, PTPN1, PTPN6, RAB1A, RAB3B, RAB6A, RAD21, RAD52, RAF1, RANBP2, RANGAP1, RAP2B, RPN2, RYK, S100A8, S100A9, TRAPPC2, SEL1L, SET, SETMAR, SGK1, SHC1, ST6GAL1, ST8SIA1, SUMO3, SNCA, SP100, UAP1, SPINK1, SRMS, AURKA, STK11, SUV39H1, ADAM17, TAF5, TAF7, TAF10, TRAPPC10, TNFRSF1A, TOP1, TOP2A, TOP2B, TTK, TWIST1, TYRO3, SUMO1, UCN, KDM6A, VEGFB, VEGFC, VRK1, VRK2, VTN, WEE1, WHSC1, XPC, XRCC4, PRDM2, BRPF1, TUSC3, NUP214, AAAS, HMGA2, SMC1A, GFI1B, BCAR3, DYRK2, TPST2, TPST1, FKBP6, OGT, HAT1, CBX4, CAMK1, MAPKAPK5, STK16, RUVBL1, USO1, DYNLL1, B4GALT4, B4GALT3, TNK1, EED, RIPK1, RIPK2, TNFRSF18, DYRK4, DPM2, NRP1, KAT2B, PROZ, HERC2, P4HA2, RPS6KA4, TNFSF18, BAZ1B, UNC119, LATS1, SMC3, DYRK1B, ARHGEF2, AURKB, CRLF1, COPB2, S1PR2, GTF3C4, B4GALT6, B4GALT5, COG1, EIF2AK3, ATG5, GOSR1, BAG4, RAB3D, SEC22B, GOSR2, CLOCK, AATK, NUP155, CTR9, TTLL4, KDM4A, NUP93, SETD1A, HDAC4, SPOCK2, SETDB1, SUPT7L, OXSR1, NR1H4, ABI1, HDAC6, GNE, UBA2, SAE1, SGK2, PREB, AKAP9, ABI2, TNK2, CWC27, HMG20B, PIAS3, RAPGEF3, SEC24B, PPIE, MAD2L2, PPIH, COG5, SEC23A, CRTAP, CARM1, SEMA4D, ATG7, SLC35A1, TRIM16, YKT6, CTCF, DCTN6, STAG2, NUP50, SEC24A, RUVBL2, ARID5A, BRD8, PRDX3, KDELR1, OS9, TMED2, IL24, WDR5, NUPL2, PRDM7, PRDM5, KAT7, CHEK2 |
1756 | GO:0007155 | 0.00 | 1.86 | 131.58 | 184 | 362 | cell adhesion | ACHE, ACTB, ACTG1, AMBN, AMBP, APLP1, APP, ARF6, ASTN1, ATP4B, AZGP1, ADGRB1, BAX, BCL3, BGLAP, DST, ZFP36L2, BYSL, RUNX2, CCND3, CD7, CD8A, CD8B, CD9, TNFSF8, SIGLEC6, SCARB2, ENTPD1, CD58, CD72, ADGRE5, CD151, CDH3, CDH6, CDH7, CDH8, CDH9, CDH10, CDH12, CDH15, CDH17, CCR3, CCR8, COL4A3, COL4A6, COL6A1, COL6A2, COL6A3, COL12A1, COL15A1, COMP, CLDN3, VCAN, CSRP1, CTNNA1, CTNNA2, CTNND2, CTPS1, CX3CR1, CXADR, DSC2, DSP, F2RL1, FAP, FCER1G, FLT3, B4GALT1, GNAS, GP1BA, GP9, RAPGEF1, GRID2, HCK, HSPB1, ICAM2, ICAM3, ICAM4, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGFALS, INS, INPPL1, ITGA9, ITGAD, ITGAM, ITGAX, KIT, LPP, KITLG, CD200, NRCAM, OMD, OLR1, OMG, OPCML, P2RX7, CNTN3, PCDHGC3, PCDH7, PCDH8, PCDH9, PGM5, RELN, PSEN1, PTPRD, PTPRM, PTPRS, PVR, RAB27A, RAG2, RAP2B, PRPH2, RELB, RPL22, RS1, S100A8, S100A9, SATB1, SELE, SELL, SELPLG, SHC1, SLC11A1, SPAM1, STAT6, STK10, STK11, STXBP1, STXBP3, ADAM17, ICAM5, TNFAIP6, TPBG, CRISP2, TRO, TNFRSF4, ZAN, FZD5, FZD8, SRPX, SORBS2, CNTNAP1, DCHS1, STX11, CTNNAL1, SIGLEC5, NRP2, WISP3, WISP1, CLDN12, CLDN10, CLDN8, CLDN6, CLDN1, FIBP, IL32, SLIT2, ITGBL1, NRXN3, NRXN1, NRXN2, THEMIS2, BCAR1, CLCA2, SDC3, FARP2, GNE, TROAP, CHST4, GPA33, CD96, TNIP1, SPON2, SPON1, GPNMB, PDPN, CHL1, EMILIN1, BTN3A1, PTPRT, IL1RAPL1 |
1757 | GO:0055080 | 0.00 | 1.86 | 44.06 | 62 | 120 | cation homeostasis | ABCB7, ACO1, AGTR2, ALAS2, XIAP, APLP2, ARF1, ATP1A1, ATP1A3, ATP12A, ATP1A4, ATP1B3, ATP4A, ATP6V1A, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, AVPR2, BMP6, CA2, CFTR, CLCN3, CLN5, COMT, FTL, HIF1A, HPX, KCNH2, KCNJ2, KCNJ10, LTF, NUBP1, SLC11A2, OTC, PDK4, PTGER4, RHAG, SCN7A, SCNN1A, SCNN1B, SCNN1G, SCO1, SGK1, SLC9A1, SLC9A2, SLC9A3, SLC9A5, SOD1, UPK3A, RAB7A, PICALM, ATP6V0D1, ABCG2, ATP6V1G1, HEPH, ABCB6, SGK2, SLC9A6, CORIN, SLC26A1 |
1758 | GO:0051783 | 0.00 | 1.86 | 38.52 | 54 | 103 | regulation of nuclear division | BIRC5, ATM, ATRX, BMP4, BUB1B, CAV2, CCNB1, CD28, CDC20, CDC25C, CDC27, CDC42, CENPE, CENPF, CHEK1, CSNK2A1, CSNK2A2, DAPK3, DRD3, DUSP1, EDN3, EREG, FGFR3, GPR3, IGF1, IGF1R, IGF2, IL1A, IL1B, INS, CHMP1A, PDE3A, PRKAR1A, PTEN, RAD1, RB1, AURKA, TTK, ZNF207, CUL3, CDC14A, CDK13, BECN1, CDC23, CDC16, ZW10, MAD2L1BP, DLGAP5, CUL7, TOM1L1, ANAPC10, MAD2L2, UBE2C, CIT |
1759 | GO:1903510 | 0.00 | 1.86 | 30.67 | 43 | 82 | mucopolysaccharide metabolic process | ANGPT1, CD44, VCAN, CSPG4, DCN, GPC4, GALNS, B4GALT1, GPC3, GLB1, GUSB, HEXA, HEXB, HGF, HMMR, IDS, IDUA, IL1B, IL15, ITIH1, ITIH3, ITIH4, LUM, CHST6, OMD, OGN, PIM1, PTGER4, SDC2, SDC4, SLC9A1, B4GALT4, B4GALT3, B4GALT6, B4GALT5, CHST3, SDC3, SPOCK2, ABCC5, GPC6, B3GNT3, SLC35D2, KERA |
1760 | GO:0046889 | 0.04 | 1.86 | 14.96 | 21 | 40 | positive regulation of lipid biosynthetic process | ANXA1, APOA1, AVP, BMP6, CREB1, CREBL2, ACSL3, GPLD1, HTR2C, IFNG, IL1B, INS, PRKAA1, PRKCD, SREBF1, TNFRSF1A, NR1H2, NSMAF, RGN, ABCG1, SORBS1 |
1761 | GO:0035966 | 0.00 | 1.85 | 39.27 | 55 | 105 | response to topologically incorrect protein | AARS, ACADVL, ADD1, ASNA1, ATF4, BAX, CCND1, SERPINH1, CLU, TPP1, CTH, DDIT3, EIF2S1, EP300, ERN1, EXTL3, HDGF, DNAJB2, HSPA4, HSPA6, HSPA8, HSPB1, HSPB2, HSP90AA1, HSP90AB1, IFNG, DNAJB9, ATXN3, PARK2, EIF2AK2, PTPN1, SDF2, SHC1, SSR1, SULT1A3, HSP90B1, WFS1, ZBTB17, MANF, ATP6V0D1, VAPB, EIF2AK3, GOSR2, TATDN2, CUL7, HDAC6, BCL2L11, PREB, PDIA6, CREB3, SEC61B, PDIA5, COPS5, KDELR3, SEC63 |
1762 | GO:0016043 | 0.00 | 1.85 | 187.13 | 261 | 552 | cellular component organization | ABCA4, ACACB, ACADL, ACADS, ADAR, ADSL, AGTR1, AGTR2, ALAD, ALDOB, ALOX12, ANXA6, APCS, BIRC3, APLP2, ARG1, ASL, FXYD2, ATP6V0A1, BCL3, BTG1, CAT, SERPINH1, CD3E, CD3G, CD38, ENTPD2, CD151, CDA, CDH3, CDH6, CDH7, CDH8, CDH9, CDH10, CDH12, CDH15, CDKN1A, CLGN, CHRNB4, CISH, AP1S1, COMP, COX15, CRYZ, VCAN, CTH, DECR1, DHCR24, DLG2, DYNC1I1, DPAGT1, EIF2S3, EPRS, EXTL3, FBLN2, FCGR1A, FLNC, FTL, GDF9, B4GALT1, GJA4, GJA5, GJB1, GLRA1, GLS, GLUL, UTS2R, GPX3, HBA2, HBE1, UBE2K, HMGCR, ICAM2, ICAM3, ICAM4, IGFBP2, IGFBP3, IGFBP5, IGFBP6, IL1RAP, IMPDH2, EIF3E, IRAK1, ITGAD, ITGAM, KCNA1, KCNA2, KCNA3, KCNA4, KCNA10, KCNC1, KCNC2, KCND2, KCND3, KCNJ2, KCNJ12, KCNS2, KCNS3, KPNA3, IPO5, KRT5, LAMA4, LCAT, LIM2, LIPC, LTBP1, LTBP2, LUM, SMAD1, MAL, MATN3, MFAP3, OAT, TNFRSF11B, OTC, P2RX1, P2RX3, P2RX4, P4HA1, SERPINA5, VIT, SERPINB5, PIGR, PIK3CB, PLN, PPIB, PPP2R1B, EIF2AK2, PTPRS, PVR, RAB4A, RABIF, RAD52, RPN2, RRM1, RRM2, RSU1, RXRG, RYR3, SCO1, SELP, SEMG1, SRSF1, SRSF5, SRSF6, SFSWAP, SH3BGR, SHMT1, SHMT2, SLC2A1, SLC2A4, SLC12A1, SLC34A1, SLC22A1, SNRPC, SNRPD2, SNRPE, SOX12, SPAM1, SPINT1, SRP9, SRP14, SRP19, SRP68, TRIM21, SSR1, STXBP3, TAF2, TBCA, TNFAIP3, TRAF1, TRAF2, TRIP6, TRO, USP4, UPK2, VBP1, VCAM1, ZNF148, PXDN, MADCAM1, CLPP, RECK, SOAT2, TPST2, PRPF18, EIF3G, EIF3J, SRSF9, DGAT1, TNK1, TRADD, URI1, RIPK1, WISP3, WISP1, CDC123, AP1S2, TRPA1, CLDN12, CLDN6, CLDN1, PRPF3, RABEP1, SCAF11, AP4M1, REPS2, SLC9A3R2, SLC22A6, ZFYVE9, LIPG, CIAO1, DDX23, AKAP6, ADAMTS3, ADAMTS2, EI24, ABCG1, SNCAIP, PDE4DIP, SDC3, CLINT1, ADAMTSL2, SNX17, KEAP1, AP1M2, ATP9A, SGK2, AASS, TNK2, TRIM22, CD2BP2, PPIH, COG5, EIF3M, CREB3, CRTAP, FBLN5, PRDX4, CCT6B, USP39, NRG3, MALT1, DHRS4, KDELR1, SF3A3, SEC61B, SPINK5, CCDC85B, STON1, UPK1A, ADRM1, OGFR, ESM1, EMILIN1, SLC7A9, AP4S1, PSIP1, DDX20, SEC63 |
1763 | GO:0048583 | 0.00 | 1.85 | 28.58 | 41 | 85 | regulation of response to stimulus | ADCY5, ATF4, BAG1, CDK6, CHEK1, DHFR, EFNA5, EPHA5, FUT8, GABRA4, HP, HSPA8, NUP88, NUP98, OGG1, PPP4C, PYCR1, RAD51, RAD52, RANBP2, RPA2, RPA3, SRSF6, DNAJC7, UBE2V2, VIL1, NUP214, AAAS, CUL4A, HMGN3, BAG3, NUP155, NUAK1, FBLN5, RAD51AP1, NUP50, USP19, OS9, NUPL2, ZNF277, CHEK2 |
1764 | GO:0071705 | 0.00 | 1.85 | 160.24 | 222 | 430 | nitrogen compound transport | ABCA1, ACACB, ACVR2B, ADCY5, ANXA1, ANXA5, AQP6, AQP7, ARG1, ARL2, ARNTL, ATP1A2, AVP, BAD, BCL3, BLK, CA2, CACNA1A, CACNB4, CCK, CD38, CDH17, CFTR, CHRM3, CPT1B, CPT2, CRHBP, CRYM, CTNS, CYLD, EDA, EDN3, EDNRA, EFNA5, EIF4E, EIF5A, EPHA5, FGA, FGG, FOLR3, GCG, GHRH, GHRHR, GHSR, GIF, GJB1, GLE1, GLP1R, GLS, GLUD1, GLUL, GNAS, GPLD1, GPR27, FFAR1, HHEX, HIF1A, HMGCR, FOXA2, AGFG1, HTR2C, IFNG, IL1B, IL1RN, IL10, IL12B, IL18, INS, ISL1, ITPR1, ITPR2, KCNC2, KCNJ10, KCNJ11, KCNS3, KISS1, SEPT2, NTRK2, NTSR1, NUP88, NUP98, OAZ1, OAZ2, OXCT1, P2RX7, PRDX1, PDE3B, PDE4C, PFKFB2, PPM1A, PPM1B, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRKCQ, PSEN1, PTGER4, PTPRN, PTPRN2, RAB1A, RAF1, RAN, RANBP2, UPF1, REST, RFX3, RHAG, RHCE, RHD, RPS28, S100A8, S100A9, SEC14L1, SRSF1, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SLC1A3, SLC1A6, SLC1A7, SLC2A1, SLC6A6, SLC6A7, SLC6A11, SLC6A12, SLC6A13, SLC7A1, SLC7A4, SLC11A1, SLC12A2, SLC15A1, SLC15A2, SLC16A1, SLC22A5, SNAP25, SREBF1, STXBP1, STXBP3, ABCC8, SYT1, SYT5, TAF7, SERPINA7, HNF1A, TRIP6, TRPC4, TRPM2, TSC1, TST, U2AF1, UCN, UPK3A, VIP, TRPV1, PAX8, NUP214, CUBN, AAAS, SLC7A5, SLC14A2, KHSRP, SLC25A12, VAMP8, SRSF9, RIPK1, TNFSF14, ARHGEF7, SLC5A6, SYT7, SLC6A5, SLC28A1, HMGN3, SLC9A3R1, NRXN1, SLC22A13, QKI, EIF2AK3, STXBP5L, LITAF, CLOCK, NUP155, NUP93, RIMS2, EIF4A3, CKAP5, TOMM20, C2CD2L, ZC3H11A, SMG7, RBM8A, NR1H4, COL4A3BP, SLC25A13, SLC25A15, DDX39A, SLC35B1, RAPGEF3, SLC25A17, NXF1, ARL6IP5, SLC35A1, RBCK1, IGF2BP3, KHDRBS1, GIPC1, NUP50, CPLX1, EDAR, RNPS1, SERINC3, SLC35D2, RAPGEF4, NUPL2, CAPN10, SLC7A9, NUDT4 |
1765 | GO:0043588 | 0.01 | 1.85 | 24.97 | 35 | 67 | skin development | AARS, ALOX12, STS, BCL2, COL1A1, COL3A1, COL5A2, CTSV, DBI, DHCR24, EDA, FGF7, GNAS, IGFBP5, ITGA3, ITGB4, KRT1, KRT9, LAMA5, OVOL1, PSEN1, RYR1, SNAI1, SOX9, SRF, FZD6, PTCH2, TRADD, CLDN1, ADAMTS2, ABCB6, EDAR, SLC27A4, SPINK5, SOX21 |
1766 | GO:0035113 | 0.01 | 1.85 | 23.56 | 33 | 63 | embryonic appendage morphogenesis | ALX3, BAX, BMP4, BMPR1A, RUNX2, DLX5, DLX6, EN1, FGF4, GJA5, GPC3, GNAQ, GNAS, HOXC10, HOXC11, HOXD9, HOXD10, HOXD11, HOXD12, IHH, AFF3, PBX1, PRRX1, PSEN1, RARB, SALL1, TULP3, TWIST1, FZD6, RECK, TP63, ALDH1A2, BCL2L11 |
1767 | GO:0046496 | 0.01 | 1.85 | 23.56 | 33 | 63 | nicotinamide nucleotide metabolic process | ALDOB, ALDOC, ARNT, ENO2, ENO3, GAPDH, GPD1, HIF1A, IDH1, IGF1, INS, LDHA, MDH1, MDH2, OGDH, P2RX7, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PGM1, PPP2R5D, PRKAA1, PRKAG1, PTGIS, RPE, STAT3, PDHX, OGT, KYNU, TP53I3, HDAC4 |
1768 | GO:0044763 | 0.00 | 1.85 | 435.11 | 550 | 1530 | single-organism cellular process | ABO, ACAA1, ACADL, ACADM, ACADS, ACADSB, ACLY, ACO1, ACO2, ACY1, ADH5, PARP4, ADSL, ADSS, AHCY, AK1, AK2, AK4, ALDH1A1, ALDH3A1, ALDH1A3, ALDH9A1, ALDH3A2, ALDOC, ALX3, AMPD1, AMPD2, AMT, AOX1, APCS, APRT, ARG1, ARG2, PHOX2A, ARSA, STS, ARSD, ARSE, ARSF, ART1, ART3, ASCL2, ASL, ASS1, AUH, BACH1, BARD1, BCAT1, BCKDHA, BHMT, BNIP2, BPI, BTD, BYSL, C1QC, CA4, CA5A, RUNX1T1, CBFB, SERPINH1, CBR1, CCBL1, CCNH, CDH7, CDH9, CDH10, CDH12, CDH15, CDO1, CD52, CDX1, CDX2, CDX4, CLGN, CEBPE, CHD2, CHKB, TBCB, CKM, CLC, CLN5, COMP, CPS1, CRAT, CRX, CRYGB, CRYM, CSE1L, CSRP1, CSRP2, CTPS1, CYC1, CYLC1, CYLC2, CYP2A6, CYP2A13, CYP2F1, CYP3A4, CYP8B1, CYP11B1, DAD1, DAZ1, BRINP1, DBT, DDX1, DDX6, DHX9, DECR1, DHCR7, CYB5R3, DLX6, SARDH, DNASE1, DNASE1L2, DNASE2, DPAGT1, DPYD, DTYMK, DUT, E2F6, TYMP, ECH1, EEF1A2, EEF2, EIF2B1, ELAVL1, ELAVL3, EN1, ENO2, ENO3, EPRS, EYA4, ERCC3, ERCC5, ERF, ESD, ETV3, ETV6, EVPL, EVX1, EXTL1, FAAH, FABP2, FABP6, FABP7, FANCE, FANCB, FANCG, FBLN2, FCN2, FDFT1, FDPS, FDXR, FLG, FLI1, FLNC, FUT6, GABPA, GALC, B4GALNT1, GALK1, GALNS, GALNT1, GAMT, GATM, GGT7, GIF, GK2, GLB1, GLDC, GM2A, GOLGB1, GOT2, GP9, GPD1, GPD2, GPT, GSTM1, GSTZ1, GUCA2A, GUCA2B, GYS2, GZMH, HIST1H2AE, HIST1H2AD, H2AFZ, HAL, HEXA, HLF, HLX, HMGN1, HMGCL, HMGCS1, HMGCS2, HMX2, HNMT, HNRNPD, HOXC10, HOXD9, HOXD10, HOXD11, DNAJB2, HSPA9, ICAM4, IDH1, IDH3A, IDS, IMPDH1, IMPDH2, IDO1, IVD, JUND, KHK, KRT5, LCAT, LIM2, LIPC, LIPE, FADS3, LMO1, LTA4H, LUM, MAT2A, MATN3, CHST6, MDH2, MEOX2, MFAP3, MGAT2, MGMT, ALDH6A1, CD200, TONSL, NRL, OAT, ODF1, OMD, OGG1, OPCML, ORC1, ORC2, ORC4, ORC5, OTC, OVGP1, OVOL1, P4HA1, PA2G4, PAFAH2, PAH, SERPINB2, PAX4, PBX1, CDK17, PCYT1A, ENPP3, PEPD, PFAS, CFP, PFDN1, VIT, PGAM1, PGGT1B, PGK1, PGM1, PGM3, PHKA1, PHKA2, PHKB, PHKG1, SERPINB9, SERPINB13, PIGC, PPIB, PPL, PRCC, PRPSAP1, PSPH, PTPRH, PTPRS, PURA, PVR, PYCR1, ALDH18A1, PYGB, PYGL, PYGM, QDPR, RAD23B, RAD52, RAG2, RBL2, RENBP, REV3L, RNPEP, RPE, RRM1, RRM2, ACSM3, SCO1, SDHA, SDHB, SDHC, SDHD, SRSF4, SRSF5, SRSF6, SFTPB, SGCB, SGTA, SHMT1, SHMT2, ST6GAL1, ST8SIA1, SIM2, SMARCA1, SMARCA2, SMS, SUMO3, SOX3, SOX12, UAP1, SPIB, SPINT1, SPRR1B, SPRR2A, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3, SRY, SSRP1, ST14, SULT1E1, SULT1A1, SULT1C2, SULT2B1, SUOX, TAF2, TAF4B, TAGLN, TAF6, TARS, TAT, TBP, TPD52, TRO, TSN, TSPY1, TST, TTC3, TUBA3C, TYMS, TYR, TYRP1, UBE2E2, UBE2L3, UBE2V2, UBTF, UCP1, UGDH, UGP2, UGT2B4, UGT2B7, UNG, UPK2, UPK3A, UQCRC2, USH2A, VBP1, ZAN, XPC, XRCC4, YY1, ZFP36, ZNF3, ZNF91, VEZF1, RNF112, RNF103, AIMP2, SHFM1, CUBN, PDHX, CDK2AP1, DPF1, ACOX2, ACOX3, HIST1H2AK, HIST2H2AC, PIP5K1B, TAGLN2, BBOX1, SOAT2, KLF11, SMARCA5, PARG, DDO, CBX4, API5, AGPS, PIR, CDC14B, PDXK, HSD17B6, DDX3Y, ALDH4A1, GALNT4, DGAT1, B4GALT4, B4GALT3, B3GALT2, EDF1, RIOK3, SCEL, SUCLG2, SUCLG1, SUCLA2, CDKL1, DPM2, SAP30, GGH, ALKBH1, TSC22D1, EIF2B3, AP1M1, HERC2, MBD4, KYNU, HIST1H2AG, P4HA2, USP13, TAF1C, TAF1B, TAF1A, CH25H, PAPSS2, PAPSS1, CLDN12, CLDN6, CLDN1, USP2, KRT75, RABEP1, EXO1, DDX21, ZMYM6, CCPG1, BCL7C, GTF3C5, B4GALT6, B4GALT5, CNOT8, COG1, LIPG, CIAO1, RECQL4, FADS2, HAND1, PIGL, ADAMTS2, MPDU1, EI24, TP53I3, CHD1L, MINPP1, SOX13, PTDSS1, KEAP1, SPATA2, GINS1, ZBTB24, EPM2AIP1, XYLB, HS3ST4, HS3ST3B1, DMTF1, ACOT8, GNE, PIGK, AP1M2, SAE1, AASS, DHRS9, DHRS2, CTDSPL, ZNF443, LRRC17, GLYAT, IRX5, SAP18, SMNDC1, SPEG, BCKDK, MARCH6, IKZF1, AKR1A1, TMEM5, B3GNT3, HMG20B, HMG20A, KLF2, CEPT1, PRG3, PEMT, SPON1, CDIPT, ARIH2, PPIE, ECI2, GPNMB, COG5, CRTAP, ENOX2, CIB2, DEAF1, RNASEH2A, SCGN, RAD51AP1, FARS2, CGRRF1, FUT9, CERS1, TOB2, FAXDC2, ALDH1L1, USP19, DHRS4, RNPS1, DBF4, UGT2A1, KDELR1, OS9, ACOT2, ASCC3, COPS6, SDS, SLC27A2, SPINK5, CCDC85B, KDELR2, KERA, RPP14, HIBADH, EMILIN1, HHLA2, SOX21, WDR6, DDX20 |
1769 | GO:0006338 | 0.00 | 1.85 | 32.16 | 45 | 86 | chromatin remodeling | ACTB, ACTL6A, RERE, ATRX, BRDT, CDKN2A, CENPA, CHD4, CHEK1, ESR1, CENPI, KAT2A, HMGA1, HNRNPC, RB1, SATB1, SMARCA1, SMARCA2, SMARCA4, SMARCC2, SMARCD1, SMARCD3, SMARCE1, SOX9, SUPT4H1, TOP1, TTF1, HMGA2, HIST1H4I, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, RUVBL1, TP63, KAT2B, RNF8, BAZ1B, CHD1L, HDAC4, RUVBL2 |
1770 | GO:0071773 | 0.00 | 1.85 | 32.16 | 45 | 86 | cellular response to BMP stimulus | ABL1, ACVR1, ACVR2A, ACVR2B, ACVRL1, XIAP, BMP1, BMP3, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, RUNX2, DLX5, FBN1, GATA4, GATA6, GDF9, GPC3, HES1, RBPJ, ILK, ITGA3, KCND3, SMAD1, SMAD6, SMAD7, SMAD9, PCSK6, PPM1A, RYR2, SOX11, SPINT1, WNT1, ZNF8, USP9X, USP9Y, CHRD, PHOX2B, SLC33A1, CER1, ZFYVE16, FSTL3, ADAMTS7 |
1771 | GO:0002443 | 0.01 | 1.85 | 25.69 | 36 | 69 | leukocyte mediated immunity | JAG1, ANXA3, BCL3, SERPING1, C1QA, C1QB, C1QC, C1S, C7, CD8A, CLU, CR2, CTSH, DBH, ACE, EMP2, ERCC1, KIT, KLRC2, KLRD1, CD46, PRDX1, PRKCD, RAB27A, S100A13, SLC11A1, STXBP3, ADAM17, LAT2, STX11, RNF8, EXO1, BTN3A3, SPON2, CPLX2, CORO1A |
1772 | GO:1901568 | 0.03 | 1.85 | 15.71 | 22 | 42 | fatty acid derivative metabolic process | ALOX12, ALOX15B, ANXA1, AVP, DAGLA, CBR1, CYP2A6, CYP2A13, CYP2F1, DPEP1, FAAH, GGT7, GPX1, HPGD, LTA4H, PTGIS, PTGS1, RNPEP, TNFRSF1A, AKR1C3, PRG3, PDPN |
1773 | GO:0030097 | 0.00 | 1.85 | 67.27 | 94 | 182 | hemopoiesis | ABL1, ABL2, ANGPT1, ATM, AXL, BAD, BAX, BCL2, BCL3, PRDM1, BMI1, BRCA2, ZFP36L2, BTK, RUNX2, CD3D, CD3E, CD4, CD8A, CD28, CD80, TNFSF8, CR2, GPR183, EEF2, EGR3, EML1, ERCC1, FCER1G, FLT3LG, GAS6, ONECUT1, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IL1B, IL2RA, IL10, IL15, ITGA4, ITGB1, KDR, CD46, NTRK1, PBX1, PGM3, PRKCZ, PTGER4, RAG1, RAG2, REST, RPL22, SATB1, SRSF4, SLC8A3, SOD1, SOS1, SOS2, SPN, STAT6, STK11, ADAM17, TAZ, ZEB1, TOP2A, TPD52, TSC1, TYRO3, VCAM1, FZD5, PICALM, FZD7, FZD8, FZD9, GFI1B, FOXN1, AP3B1, CDK13, RIPK2, ARHGEF7, AP3D1, KRT75, KLF4, SOX13, HDAC4, ZBTB24, SH2B3, TACC3, EBP, MALT1, SPINK5, BVES |
1774 | GO:0001558 | 0.00 | 1.85 | 37.86 | 53 | 102 | regulation of cell growth | ACVRL1, AGTR1, AGTR2, FXYD2, BST2, BTG1, CAV3, CDA, CDK11B, CDKN1A, CDKN2A, CISH, CTGF, GDF9, HRG, IGFBP2, IGFBP3, IGFBP5, IGFBP6, SMAD3, PPP2R1A, PRKCQ, PTPRJ, SIPA1, SLIT3, SMARCA2, SMARCA4, SPOCK1, STK11, TRO, TSG101, WNT11, BAP1, BLZF1, TNK1, URI1, ADAM15, WISP3, WISP1, CTDP1, TAOK2, EI24, BCAR1, ARHGEF11, SGK2, MAD2L2, CREB3, FBLN5, GAS2L1, NRG3, CCDC85B, OGFR, ESM1 |
1775 | GO:1903530 | 0.00 | 1.84 | 55.77 | 78 | 151 | regulation of secretion by cell | ABL1, ABL2, ACHE, ALOX15B, ANG, ARF1, ATP6AP1, AVP, CAMK2A, CASP1, CASP5, CCK, CD58, CHRNB2, CHRNB4, CRP, CSF1R, FCER1G, FGR, B4GALT1, GJA5, GLRA1, IGF1, IL1A, IL13, IL17A, KCNA2, KCNN4, LLGL2, NTRK2, NTSR1, OXTR, P2RX7, PAEP, PAM, PCP4, PFN2, PIK3C3, SEPT5, PPID, PRKCQ, PRKCZ, PTAFR, RAB3B, RAB5A, RAB27A, RAB27B, RAC2, RALA, SDC4, SDCBP, SLC18A1, SPINK1, STXBP2, SYN1, SYT1, TRAF2, TSG101, TWIST1, NR1H2, VEGFC, RAB7A, STAM, DOC2A, ADAM9, IL1RL1, RAB9A, ATG5, RAB3D, SNCAIP, RIMS2, GAB2, PDCD6IP, TRIM16, SEC24A, CPLX2, CPLX1, GLMN |
1776 | GO:0043086 | 0.00 | 1.84 | 96.99 | 135 | 262 | negative regulation of catalytic activity | ACACB, ADAR, ADARB1, ADRA2A, ANXA3, ANXA5, ATM, BMP4, BUB1B, CALU, CAV3, CCNB1, CDC20, CDC27, CDKN1A, CDKN2A, CENPF, CHAD, CISH, CNR1, CNR2, DCN, GADD45A, DRD3, DRD5, DUSP1, DUSP4, DUSP5, EPHA1, GALR1, GFI1, GNAQ, GP1BA, HHEX, HMGCR, FOXA2, HP, HSPB1, IGF1R, IL1B, IL13, ILK, INS, LIMK1, SMAD7, CD46, PPP1R12A, OAZ1, OAZ2, PALM, PARK2, PCP4, PDC, PDE6G, PDE6H, PPP1R1A, PPP1R2, PPP1R8, PPP2R1A, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRPSAP1, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTN, PTPN1, PTPN6, PTPRJ, RANBP2, RB1, ABCE1, SAG, SET, SLN, SNCB, TAF7, NR2F2, TNFAIP3, TP73, TSC2, TTK, UBB, SCGB1A1, ZNF207, CUL3, DGKZ, CDC23, KAT2B, CDC16, SOCS3, LATS1, ZW10, ITGB1BP1, SOCS6, BAG5, APBA3, GABBR2, PHACTR2, PSMD6, HDAC6, PSME3, PSMD14, TRIB1, ANAPC10, MAD2L2, HEXIM1, TXNIP, CERS1, ARPP19, UBE2C |
1777 | GO:0002698 | 0.03 | 1.84 | 16.44 | 23 | 44 | negative regulation of immune effector process | A2M, ANXA1, BCR, SERPING1, CD59, HLX, IFIT1, IGF2, IL2RA, INS, CD46, PCBP2, SERPINB9, PPM1B, EIF2AK2, PTPN6, RPS19, SERPINB4, SEC14L1, SPN, TNFSF4, TNFSF18, TRIM38 |
1778 | GO:0048513 | 0.00 | 1.84 | 130.27 | 183 | 379 | animal organ development | ACTN1, ACVR2A, ADAR, ADD1, AHSG, ALAS2, AMELY, AMHR2, APCS, BCL2L1, BCL3, BMI1, ZFP36L2, BTK, C1QC, CAPN5, CAMK4, CASP9, CBFB, CD3D, CD3E, CD4, CD8A, CD28, CD80, CD86, TNFSF8, CDKN2A, CEBPE, CHAT, CLU, COL9A3, CR2, CTLA4, CYLD, DNASE2, GPR183, ECM1, EDN3, EFNB1, ETV6, F2RL1, FANCA, PTK2B, FANCF, FANCG, FCER1G, FSHB, CENPI, FSHR, GABPA, GDF9, HSD17B10, HCLS1, HNF4G, IAPP, ICAM1, IDH1, IFI16, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IL1B, IL2RA, IL12B, IL15, IL17A, ING2, INHA, INS, INSL3, IRF1, CD46, SLC11A2, NRTN, NTRK1, OMD, PDE3B, PDE1B, PF4, PGM3, PHEX, PRKACG, PRKCZ, EIF2AK2, PTPRN, RAB13, RAG2, RELB, RFX3, RHAG, RHEB, RPL22, RPS19, S100A4, SATB1, SERPINB3, SDCBP, SEMA3F, SRSF4, SOS1, SOS2, SPN, SRY, ADAM17, KLF10, TMF1, CLEC3B, TOP2A, TPD52, TSPY1, TNFSF4, XRCC5, ZNF16, CSDE1, SEMA3B, FGF23, NRIP1, HIST1H4I, PICALM, FZD8, FZD9, GFI1B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, PIR, AP3B1, CDK13, RIPK1, TNFSF9, RIPK2, INPP4B, NRP2, ARHGEF7, EIF2B2, EIF2B5, EIF2S2, AP3D1, TNFSF18, KRT75, DYRK1B, ITGB1BP1, GPR55, NRG2, MINPP1, CLOCK, SOX13, TRAF4, CTR9, ZNF516, SEMA3E, ZBTB24, GAB2, FARP2, REC8, AKAP9, RNF41, DHRS2, PRG4, TRIB1, ARIH2, GPNMB, MAD2L2, SEMA6C, SEMA6B, SEMA4F, SEMA4B, PRDX4, CXCL13, GAS2L1, EBP, TOB2, MALT1, STRAP |
1779 | GO:0072524 | 0.01 | 1.84 | 25.06 | 35 | 67 | pyridine-containing compound metabolic process | ALDOB, ALDOC, AOX1, ARNT, ENO2, ENO3, GAPDH, GPD1, HIF1A, IDH1, IGF1, INS, LDHA, MDH1, MDH2, OGDH, P2RX7, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PGM1, PPP2R5D, PRKAA1, PRKAG1, PTGIS, RPE, STAT3, PDHX, OGT, PDXK, KYNU, TP53I3, HDAC4 |
1780 | GO:0098727 | 0.01 | 1.84 | 25.06 | 35 | 67 | maintenance of cell number | JAG1, ASCL2, BMPR1A, ZFP36L2, CDX2, DDX6, EIF4E, ELAVL1, EPHA1, FGF4, FGFR3, HES1, IGF1, RBPJ, KIT, CNOT2, PBX1, PCM1, PRRX1, RAF1, SALL1, SOX2, SOX9, STAT3, TAL1, KLF10, PAX8, HMGA2, SMC1A, FZD7, CUL4A, SMC3, KLF4, CTR9, STAG2 |
1781 | GO:0034138 | 0.03 | 1.84 | 16.46 | 23 | 44 | toll-like receptor 3 signaling pathway | BIRC2, BIRC3, CD86, CHUK, CREB1, ATF2, DUSP4, ELK1, F2RL1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK8, RPS6KA1, SKP1, TNFAIP3, UBB, UBE2D2, CUL1, IKBKG, RIPK1, RIPK2 |
1782 | GO:0043467 | 0.03 | 1.84 | 16.46 | 23 | 44 | regulation of generation of precursor metabolites and energy | ADRA1B, AKT2, ARNT, BNIP3, GCGR, GPD1, HIF1A, IGF1, IGF2, INS, KHK, P2RX7, PGAM1, PRKAA1, PRKAG1, SNCA, STAT3, DYRK2, OGT, HDAC4, EPM2AIP1, TRAP1, SORBS1 |
1783 | GO:0072088 | 0.03 | 1.84 | 16.46 | 23 | 44 | nephron epithelium morphogenesis | AGTR2, BCL2, BMP4, CD44, EYA1, GPC3, HOXD11, HES1, ILK, LAMA5, TACSTD2, CITED1, PBX1, PSPN, SALL1, SIX1, SOX9, STAT1, WNT1, WNT11, WNT2B, PAX8, DCHS1 |
1784 | GO:1900034 | 0.03 | 1.84 | 16.46 | 23 | 44 | regulation of cellular response to heat | ATM, ATR, BAG1, CAMK2A, EP300, HSPA8, HSP90AA1, HSP90AB1, NUP88, NUP98, RANBP2, RPA2, RPA3, DNAJC7, NUP214, AAAS, BAG5, BAG4, BAG3, NUP155, NUP93, NUP50, NUPL2 |
1785 | GO:0048736 | 0.00 | 1.84 | 34.41 | 48 | 92 | appendage development | ALX3, ATRX, BAX, BMP4, BMPR1A, BMPR2, RUNX2, COMP, DLX5, DLX6, EN1, FGF4, GJA5, GPC3, GNAQ, GNAS, HOXC10, HOXC11, HOXD9, HOXD10, HOXD11, HOXD12, IDUA, IHH, ITGB4, AFF3, MEOX2, PAM, PBX1, PCSK5, PRRX1, PSEN1, RARA, RARB, SALL1, SOX9, SOX11, NR2F2, TULP3, TWIST1, ZNF141, FZD6, RECK, FOXN1, TP63, ALDH1A2, IFT140, BCL2L11 |
1786 | GO:0002573 | 0.01 | 1.84 | 26.49 | 37 | 71 | myeloid leukocyte differentiation | ATP6AP1, BGLAP, BMP4, CA2, CDC42, CEBPE, CHUK, CREB1, CSF1R, EPHA2, F2RL1, FSHB, FSHR, GPC3, GNAS, HCLS1, HHEX, IFI16, IFNG, IL12B, IL17A, JUN, KIT, KITLG, PDE1B, PF4, RB1, TAL1, KLF10, TYROBP, OGT, PIR, RIPK1, GAB2, FARP2, TSPAN2, IKZF1 |
1787 | GO:0009894 | 0.00 | 1.84 | 141.89 | 196 | 380 | regulation of catabolic process | ABL1, ABL2, ACTL6A, ADRA1B, APAF1, ARAF, ARNT, ARNTL, ATM, ATP6V0A1, BAD, BARD1, BAX, BCL2, BCL2L1, BNIP3, BNIP3L, ZFP36L2, BUB1B, TSPO, CASP1, CAV3, CBLB, CCNB1, CD81, CDC20, CDC27, CDC42, CDKN2A, CENPF, CLU, CSNK1D, CSNK2A1, CSNK2A2, CTSK, DAB2, DAPK3, DCN, DFFA, DUSP1, EEF1A2, CTTN, ERN1, PTK2B, FAP, FYN, GATA4, KAT2A, GFAP, GPC3, GOLGA2, GPD1, GPX1, GRIN2A, HGF, NRG1, HIF1A, UBE2K, HP, DNAJB2, HSP90AB1, IFI16, IFNG, IGF1, IL10, ITGB1, KDR, KIF25, SMAD3, SMAD7, ATXN3, OAZ1, OAZ2, P2RX7, PAFAH1B2, PARK2, PGAM1, PGAM2, PIK3CB, PIP4K2A, PRKAG1, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, PTPN1, RAD23B, RB1, RDX, UPF1, SDCBP, SGTA, SKP1, SUMO3, SNCA, SNRNP70, SOX9, SREBF1, TRIM21, STAT3, AURKA, STK11, SUPV3L1, TMF1, TNFAIP3, TNFRSF1B, TSC1, TTK, U2AF1, UBB, UBE3A, SUMO1, UVRAG, VIP, WNT1, ZFP36, ZBTB17, ZNF207, FZD5, RAB7A, EPM2A, USP5, CUL3, CUL1, OGT, RUVBL1, BECN1, CDC23, ADAM9, CDC16, USP13, USP14, RGN, AIFM1, ZW10, CNOT8, RAB33A, ATG5, PSMF1, TMEM59, BAG5, SEC22B, GTPBP1, RNF14, FEZ2, KDM4A, DHX34, HDAC4, DLGAP5, RNF40, KEAP1, RB1CC1, PSMD6, KCNE2, HDAC6, PSME3, TRIM13, PSMD14, TRIB1, APC2, TRIM22, ANAPC10, RAPGEF3, ARIH2, MAD2L2, ATG7, RRAGA, GIPC1, USP19, OS9, PIM2, UBE2C, GLMN, WDR6, CHEK2 |
1788 | GO:0061041 | 0.03 | 1.84 | 17.89 | 25 | 48 | regulation of wound healing | ABAT, ADRB2, ALOX12, ANXA5, APCS, SERPING1, F2RL1, FAP, FCER1G, FGA, FGG, GP1BA, HMGCR, FOXA2, KLKB1, KNG1, KRT1, SMAD3, SERPINB2, PRKCD, PRKCQ, PROC, SRSF6, TNFAIP3, VIL1 |
1789 | GO:0048593 | 0.03 | 1.84 | 17.19 | 24 | 46 | camera-type eye morphogenesis | JAG1, ALDH1A3, AQP5, BAX, GNAT2, HMGN1, IHH, KDR, PTN, PTPRM, RPGR, RPE65, RS1, SOX9, SP1, ZEB1, TWIST1, WNT2, WNT2B, YY1, FZD5, SLC4A7, IRX5, IKZF1 |
1790 | GO:0006606 | 0.02 | 1.83 | 19.31 | 27 | 52 | protein import into nucleus | ADAR, AGTR2, RERE, CBLB, CSE1L, F2R, FYB, GNAQ, HES1, KPNA2, KPNA3, KPNA4, KPNA5, NUP88, NUP98, PRDX1, RANBP2, STAT3, TSC2, NUP214, FZD7, RGS20, RPL23, NUP155, IPO13, NUP93, TXNIP |
1791 | GO:0015849 | 0.00 | 1.83 | 66.95 | 93 | 179 | organic acid transport | ABAT, ACACB, AGTR2, AGXT, AKT2, ALB, ABCD1, ANXA1, ARG1, ATP1A2, AVP, BDKRB2, CACNA1A, CACNB4, CCK, CD36, AKR1C4, CPT1B, CPT2, CTNS, ACE, DRD3, FABP6, ACSL1, ACSL3, ACSL4, FOLR3, GLS, GOT2, IL1B, KCNJ10, SEPT2, NTRK2, NTSR1, P2RX4, P2RX7, P2RY2, ATP8B1, PSEN1, ABCD3, RXRA, SLC1A3, SLC1A6, SLC1A7, SLC6A6, SLC6A7, SLC6A11, SLC6A12, SLC6A13, SLC7A1, SLC7A4, SLC10A1, SLC10A2, SLC11A1, SLC16A1, SLC25A1, SLCO2A1, SLCO1A2, SLC22A5, SNAP25, SNCA, STXBP1, SYT1, TRPC4, TRPV1, SLC7A5, SLC10A3, SLC25A12, SLC5A6, SLC13A2, SLC16A6, SLC16A5, SLC16A4, SLC6A5, SLC16A7, SLC22A6, SLC9A3R1, SLC22A13, NR1H4, SLC25A13, SLC25A15, ABCC4, SLC25A17, ARL6IP5, SLCO1B1, GIPC1, CPLX1, SLC26A1, SERINC3, SLC27A5, SLC27A4, SLC27A2, SLC7A9 |
1792 | GO:0007389 | 0.00 | 1.83 | 82.28 | 114 | 220 | pattern specification process | ACVR1, ACVR2A, ACVR2B, ALX3, ASCL1, ATM, BAX, BBS4, BMI1, BMP4, BMPR1A, BMPR2, CDX1, CDX2, CDX4, CRKL, DDIT3, DNAH5, EDNRA, EFNB1, EGR2, EMX1, EMX2, EN1, EP300, EVX1, EYA1, FGF3, GATA4, KAT2A, GPC3, GRSF1, HHEX, HIF1A, FOXA2, HOXC10, HOXC11, HOXD3, HOXD8, HOXD9, HOXD10, HOXD11, HOXD12, HES1, RBPJ, IHH, ISL1, SMAD1, SMAD3, SMAD6, MEOX2, CITED1, NTF4, OTX1, OTX2, PCSK6, PAX3, PBX1, PCDH8, PCSK5, PRKACB, MAPK8, RELN, PSEN1, PSKH1, RFNG, RFX3, SEMA3F, STIL, SIM2, SIX1, SIX3, SMARCD3, SNAI1, SOX1, SRF, STC1, AURKA, ZEB1, NR2F1, NR2F2, TULP3, KDM6A, WNT1, WNT2, WNT2B, XRCC2, YY1, ZIC1, ZIC2, PAX8, FZD5, RGS20, TP63, CHRD, NRP1, ALDH1A2, SEMA5A, CER1, KIF3B, HAND1, SEMA3E, IFT140, ZEB2, ABI1, FRAT1, ATP6AP2, SPRY1, APC2, CITED2, SEMA3A, DMRT2, TBR1, NRG3 |
1793 | GO:0007268 | 0.00 | 1.83 | 87.92 | 122 | 238 | synaptic transmission | ADCY3, ADCY5, ADCY6, ADCY9, ALDH2, AMPH, ARF1, ATP2B2, BCHE, HCN2, CACNB3, CALM1, CALM3, CD38, CDC20, AP2S1, CNP, COMT, CORT, CREB1, CTNND2, CX3CR1, DBH, DBI, DLG2, DLG3, EGR2, GABRA5, GABRG1, GABRR1, GABRR2, GFAP, GNAI1, GNAL, GNB1, GNG3, GNG10, GNGT1, GNGT2, GPR1, GRIA1, GRIA4, GRM1, HRH1, HRH2, HTR2C, HTR3A, KCNA1, KCNA2, KCNA3, KCNA4, KCNA10, KCNC1, KCNC2, KCND2, KCND3, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ12, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN1, KCNN4, KCNQ1, KCNS2, KCNS3, KIF5A, KISS1, KIT, ATXN3, OMP, PCDH8, PDYN, PRKACB, PTN, RAF1, RARA, RPS6KA1, S100B, SDCBP, SLC8A3, SLC18A1, SNCB, SRF, STAR, STAU1, ABCC8, SYP, SYPL1, SYT5, CNTN2, VIPR1, KCNAB1, RAB11A, BSN, UNC119, USP14, KCNAB3, KCNK6, PICK1, APBA3, GABBR2, RIN1, RAPGEF2, SNAP91, SLC12A6, HCN4, ABCC9, AKAP9, KCNMB2, CACNG2, BAIAP2, GIPC1 |
1794 | GO:0032844 | 0.01 | 1.82 | 25.07 | 35 | 68 | regulation of homeostatic process | ADCY5, AGTR1, ALOX12, TSPO, CAV3, CCK, CD36, CDK6, DCN, EFNA5, EPHA5, FGFR4, GJA5, UBE2K, FOXA2, IL2RA, KDR, LMO1, SMAD7, PARK2, PRKAA1, SCN5A, SCN10A, ADAM17, NR1H2, SLC30A3, SLC30A4, AP3D1, HMGN3, NRXN1, NR1H4, NR1D2, HCN4, CORIN, UBE2C |
1795 | GO:0044093 | 0.00 | 1.82 | 340.72 | 461 | 917 | positive regulation of molecular function | ACVR2B, ADCY3, ADCY5, ADCY6, ADCY9, ADRA2A, ADRB2, AGTR1, AGTR2, AKT2, ALDH1A1, ALDOB, ALK, ALOX12, AMPH, ANG, ANGPT1, ANXA3, APAF1, APOA1, APOH, APP, ARAF, TRIM23, ARF1, ARHGAP4, ARHGAP6, ARHGDIB, ARL1, AVPR1B, AVPR2, BAD, BAX, CCND1, BCL2, BCR, BID, BMI1, BNIP2, BOK, BTK, CALCR, CAMK4, CAMK2A, CASP1, CASP9, CAT, CAV2, CCK, CCNB1, CCNC, CCND3, CCNH, CCNT1, CCNT2, CD4, CD81, CDC20, CDC27, CDC42, CDH3, CDKN1A, CDKN2A, CENPE, RCBTB2, CHN1, CHN2, CHUK, CLU, CLPS, COL4A3, CREB1, ATF2, CRKL, CSF1R, CSF2RB, CSPG4, CTGF, CTH, CTSH, ACE, GADD45A, DHFR, DKC1, DRD5, HBEGF, DUSP5, EDA, S1PR1, LPAR1, EDN3, EDNRA, EEF1A2, EFNA1, EFNA5, EIF2B1, EPHA2, EMP2, EPHA1, EPHA5, EPHA8, ERBB2, EREG, ERCC6, ERN1, ESR1, F2R, F3, ACSL1, PTK2B, FBLN1, FCER2, FGD1, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FGR, FLT1, FLT3, FPR1, FSHR, FYN, FZD2, GAS6, GCGR, GDI1, GDI2, GHRHR, GLP1R, GM2A, GNA15, GNAL, GNAQ, GNAS, GNAT1, GNG3, GPLD1, FFAR1, GRB2, RAPGEF1, GRIN2A, ARHGAP35, GRM1, CXCL1, GTF2F1, GUCA1A, GUCA1B, GUCA2A, GUCA2B, HGF, NRG1, HIF1A, HIP1, AGFG1, HSPB2, ICAM1, IFI16, IFNG, IGF2, IGFBP3, IL1B, IL2RA, IL10, IL12B, ILK, INS, IRAK1, IRAK2, ITGA1, ITGB1, ITPR1, ITPR2, JUN, KIT, KRAS, LLGL2, LTF, SMAD3, MARK3, MAP3K5, KITLG, MAP3K11, PPP1R12A, PPP1R12B, SLC11A2, NTF3, NTRK1, NTRK2, NTRK3, NVL, P2RX1, P2RX7, P2RY11, PEBP1, PAWR, PCNA, PCOLCE, PDE6G, PDE6H, PDE1B, PFKFB1, PFKFB2, PFN1, PFN2, PIK3CB, PIM1, PPP5C, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK8, EIF2AK2, PSAP, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, PTPN1, PTPRA, RAB4A, RABIF, RAC1, RAF1, RANBP1, RANGAP1, RAP1GAP, RAP1GDS1, RASA2, RCVRN, REST, RGS2, RGS10, RGS12, RGS13, RGS16, RPGR, RPS3, RSU1, S100A8, S100A9, S100A12, SBF1, SERPINB3, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SELE, SEMG1, SETMAR, SFTPB, SHC1, STIL, SIPA1, SKP1, SLC11A1, SMARCA4, SNCA, SOD1, SOS1, SOS2, SP100, SRF, TRIM21, CDKL5, STK10, STK11, XCL2, ADAM17, TBCD, TNNT2, TP73, TPD52L1, TRAF1, TSC1, TSC2, UBB, UBE2L3, UCN, NR1H2, VAV1, VIP, VIPR2, WFS1, WNT1, WNT2, WNT11, XRCC4, ZIC2, ZNF16, TRIM25, FZD5, ARHGEF5, FOSL1, FGF23, PICALM, FZD4, FZD8, BCAR3, NSMAF, CUL3, CUL1, OGT, IKBKG, CAMK1, MAPKAPK5, CDC14B, RGS20, PDE5A, PEA15, CDC23, S1PR4, TRADD, RIPK1, CRADD, TNFSF10, ADAM9, RIPK2, RGS11, TNFRSF10B, TNFRSF10A, CFLAR, ASAP2, CDC16, EIF2B3, EIF2B2, EIF2B5, BUD31, HERC2, RPS6KA4, KALRN, BAZ1B, UNC119, RQCD1, AIFM1, RABEP1, ARHGEF1, ARHGEF2, AURKB, VAPB, CYTH3, ITGB1BP1, GPR55, S1PR2, TRIP10, GTF3C4, TAOK2, ARHGAP29, ARHGEF6, PSMF1, STXBP5L, NRG2, CLOCK, RIN1, GUCA1C, RALGPS1, ARHGAP32, ACAP1, SLK, HDAC4, RAPGEF5, ATG13, ARHGEF11, ARHGEF17, ZEB2, EPM2AIP1, FARP2, PSMD6, SGSM2, RABGAP1L, ARHGAP25, OXSR1, TNFSF15, RBX1, CASP8AP2, ABI1, PDCD6, BCL2L10, BCL2L11, TOM1L1, SH2D3C, SH2D3A, UBA2, SAE1, RAD50, RASA4, FARP1, RNF41, PSME3, TRIM13, PSMD14, DENND4A, TRIM22, ABCA7, ANAPC10, CDC42EP2, VAV3, TRIM38, CAP1, CREB3, STK25, SEMA4D, ARL6IP5, CXCL13, ARFGEF2, ARFGEF1, CCT4, CCT2, CDC42EP3, RBCK1, NRG3, FRS3, MALT1, JTB, COPS8, DBF4, PRDX3, ADRM1, UBE2C, RAPGEF4, MAP4K5, FZD10, AKAP13 |
1796 | GO:0033554 | 0.00 | 1.82 | 50.71 | 71 | 142 | cellular response to stress | ADM, ANXA5, APOA1, CALU, CBS, CETN1, CHUK, COX8A, CREB1, CRHBP, CRKL, CTNNA1, DHX9, DNMT3B, DUSP4, ELK1, STOM, FCGR3B, SLC37A4, GABRA5, BLOC1S1, GFAP, GSTM1, GSTM2, HSPA6, INSIG1, IRAK2, ISL1, KRT15, MDH1, P2RX5, PEX13, SERPINB10, PPP2R5D, PTGER4, RBM4, RPS6KA1, RXRA, SFRP4, ST8SIA1, SIPA1, SKP1, SLC1A3, SLCO1A2, SLC22A3, SNRPD1, SNRPF, SRF, STAT2, STK10, NR2C2, ZNF189, CUL1, MAPKAPK5, EIF2B3, NREP, ARHGEF6, CHST3, SLK, PHYHIP, IST1, RB1CC1, FGFBP1, PDCD6, SH2D3C, SH2D3A, TRIB1, ARPP21, HSF2BP, CDC37, ADAMTS7 |
1797 | GO:0006950 | 0.04 | 1.82 | 13.23 | 19 | 41 | response to stress | ABCA1, ADH5, NR0B1, CDH8, CIRBP, GLP1R, IMPDH1, KCNJ11, SMAD6, SMAD7, OXTR, P2RX4, SNN, TP53I11, ZNF516, KEAP1, EIF1, ZNF443, CGRRF1 |
1798 | GO:0034728 | 0.01 | 1.82 | 29.52 | 41 | 79 | nucleosome organization | ATRX, BRDT, CENPA, CENPI, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, HIST1H1A, SOX9, TSPY1, CHAF1B, HIST1H4I, HIST1H2BG, HIST1H2BL, HIST1H2BN, HIST1H2BM, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, HAT1, RUVBL1, HIST1H3F, HIST1H2BJ, H1FX, RNF8, CTCF |
1799 | GO:1990138 | 0.01 | 1.82 | 29.52 | 41 | 79 | neuron projection extension | ABL1, ARHGAP4, BMPR2, DCX, DNM2, EMX1, CTTN, GOLGA4, NRG1, IFRD1, ILK, ITGB1, LIMK1, NRCAM, NTRK3, PARK2, PRKCZ, RNF6, SLIT3, SRF, AURKA, CDKL5, STK11, SYT1, SYT4, TNR, SEMA3B, USP9X, RAB11A, CPNE1, SEMA5A, SLIT2, AATK, RIMS2, SEMA3E, SLC9A6, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B |
1800 | GO:0051650 | 0.00 | 1.82 | 51.99 | 72 | 139 | establishment of vesicle localization | AMPH, ARCN1, AREG, ARF1, BBS2, BBS4, CACNA1A, CANX, CD59, CDH3, COPA, CSNK1D, CTSZ, DNM1, DYNC1I1, DNM2, BLOC1S1, GOLGA2, GRIA1, GRN, ITGA4, LMAN1, LRMP, P2RX7, PARK2, PFN2, SEPT5, PPP6C, PRKCZ, PSEN1, RAB1A, RAB5A, RAB27A, RAB27B, TRAPPC2, SNAP25, SNCA, STXBP1, SYN1, SYT1, SYT5, TRAPPC10, DOC2A, CUL3, IKBKG, AP3B1, USO1, CADPS, STX11, RAB11A, LIN7A, SYNJ1, AP3D1, COPB2, SNAP29, KIF3B, GOSR1, SEC22B, GOSR2, RIMS2, SNPH, AP1M2, PREB, SEC24B, SEC23A, YKT6, SEC24A, CPLX2, CPLX1, AP3M2, TMED2, KIF3A |
1801 | GO:0048731 | 0.00 | 1.81 | 165.59 | 231 | 499 | system development | ACTG1, ADAM10, ADCY6, ALK, ARAF, ARF1, ARHGAP4, ASTN1, BCHE, DAGLA, CACNB3, CALU, CAMK2A, CCK, CD72, CDC20, CHN1, CHRM1, CHRM3, TBCB, AP2S1, CLTA, CNR1, COL4A5, COL6A1, COL6A2, CSF2RB, CSNK2A1, CSNK2A2, CTNND2, DAPK3, BRINP1, DDX6, DHFR, DLG2, DLG3, DNM1, DNMT3B, DPYSL3, EPYC, ECM2, DUSP5, DYRK1A, EFNA3, EFNA4, EFNA5, EIF4G1, ELAVL3, CTTN, EPHA8, ACSL4, FGF5, FGFR4, GAK, BLOC1S1, GDI1, GFRA1, GFRA2, GJB1, GOLGA4, GRN, GRIN2A, CXCL1, HSPA8, HSP90AA1, IFRD1, ITGA1, ITGA9, KCNA2, KIF5A, LIMK1, CAPRIN1, MAP6, MARK3, ATXN3, SEPT2, NTN3, OGN, OMG, OMP, OPA1, OPCML, P2RX5, P2RY1, P2RY2, PEBP1, PALM, CNTN3, PENK, PFN1, PPP2R5D, PPP5C, PRKACB, PRKCQ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTPRA, PTPRD, PTPRR, PURA, RAC2, RALA, RAP2A, RASA2, RNF6, S100A6, SCN2A, SCN3A, SDC2, SDHA, SFRP5, SGK1, SIAH1, SLC1A3, SMARCD1, SMARCE1, SNAP25, SPAST, AURKA, CDKL5, STRN, STXBP1, DYNLT1, TPBG, TRPC1, TRPC3, TRPC5, TTC3, UCN, WEE1, XRCC2, ZNF24, RNF112, ZNF217, EPM2A, SLC7A5, RND2, DPF1, SOX14, DOC2A, CNTNAP1, GAS7, CAMK1, KLF7, BECN1, PEA15, RAB11A, KAT2B, CPNE1, BSN, RPS6KA4, KALRN, AIFM1, ARHGEF1, CBFA2T2, ARHGEF2, NREP, NRXN2, PICK1, CHST3, PSMF1, GAL3ST1, BAG5, FEZ2, RIMS2, RAPGEF5, IST1, SPOCK2, ARHGEF11, KIAA0319, PSMD6, FIG4, RNF10, NR1H4, RBX1, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, RASA4, ATP6AP2, FARP1, PSME3, PSMD14, SIGMAR1, KATNB1, HMG20A, SPON2, BAIAP2, SLC9A6, CAP1, STK25, CHERP, ARPC1A, ARFGEF1, DPYSL4, AVIL, FUT9, CHL1, CPLX2, FRS3, RAB10, AFG3L2, RAB35, STMN2, CIT, IL1RAPL1, FZD10 |
1802 | GO:0032880 | 0.00 | 1.81 | 199.35 | 272 | 533 | regulation of protein localization | ABAT, ABL1, ABL2, ACHE, ACTL6A, ADCY5, ADRA2A, AGTR2, AKT2, ALOX15B, ANG, ANGPT1, ANXA1, ANXA5, APOA1, ARF1, ARF6, ARL2, ARNTL, BAD, BARD1, BCL2, BCL2L1, BCL3, BID, BLK, BMP4, BMP6, BMPR1A, BNIP3L, BRCA1, CACNA1A, CAMK4, CASP1, CASP5, CAV3, CCNB1, CCT6A, CD36, CD38, CD58, CDC42, CDH1, CDKN1A, CDKN2A, CFTR, CHRM1, CHRM3, CNR1, CRH, CRP, CSF1R, CSNK2A2, CTSK, CYLD, DAB2, DKC1, DRD3, EDA, EFNA5, EPHA2, STOM, EPHA5, ERBB2, F2R, F2RL1, ACSL3, FBLN1, FGA, FGG, FGR, FYN, GAS6, GCG, KAT2A, GDI1, GHSR, GJA5, GLP1R, GLUD1, GLUL, GNAQ, GNAS, SFN, GPLD1, GPR26, GPR27, FFAR1, HCLS1, NRG1, HIF1A, HMGCR, FOXA2, HNMT, HES1, DNAJB2, HSPA8, HSP90AB1, IFNA2, IFNG, IGF1, IL1A, IL1B, IL10, IL12B, IL13, IL17A, IL18, INS, ISL1, ITGA3, ITGAX, ITGB1, ITPR1, ITPR2, KCNC2, KCNE1, KCNJ11, KCNN4, KCNS3, KPNA1, IPO5, LLGL2, SMAD3, SEPT2, TONSL, OAZ1, OAZ2, OGG1, OXCT1, P2RX7, PAEP, PRDX1, PAM, PARK2, PCM1, PDE3B, PDE4C, PFKFB2, PIK3C3, PPID, PPM1A, PPM1B, PPP3R1, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCE, PRKCI, PRKCQ, PRKCZ, MAPK8, PTGER4, PTN, PTPN1, RAC2, RANGAP1, RB1, RDX, REST, RFX3, RNASE2, CX3CL1, SFRP5, SIX1, SLC2A1, SLC9A1, SLC16A1, SNAP25, SP100, SREBF1, STK11, STXBP1, ABCC8, SYT5, TRAF2, CCT3, TRIP6, TRPM2, TSG101, TWIST1, TNFSF4, TNFRSF4, U2AF1, UBE2L3, SUMO1, NR1H2, VEGFC, VIL1, VIP, WHSC1, YWHAZ, ZIC1, ZBTB17, FZD5, ARHGEF5, AKAP1, PICALM, BAP1, FZD7, DYRK2, OGT, CAMK1, RGS20, RUVBL1, NUMB, DYNLL1, VAMP8, STX10, BECN1, TNFSF14, ADAM9, RAB11A, HDAC3, CDKL2, SEMA5A, SYT7, IL1RL1, ITGB1BP1, HMGN3, RAB9A, SLC9A3R1, NRXN1, CRIPT, EIF2AK3, AKAP6, ATG5, STXBP5L, LITAF, TMEM59, BAG4, CLOCK, ATG13, KEAP1, C2CD5, C2CD2L, RABGAP1L, FAM20B, NR1H4, HDAC6, BCL2L11, SAE1, NUTF2, RAMP3, APC2, TRIM22, PEMT, RAPGEF3, ARIH2, TACC3, CREB3, CHERP, CCT7, CCT4, CCT2, SORBS1, RBCK1, TRIM16, SEC24A, EDAR, OS9, YWHAQ, WWP2, RAPGEF4, RER1, CAPN10, KAT7, GLMN |
1803 | GO:0048863 | 0.00 | 1.81 | 57.16 | 79 | 153 | stem cell differentiation | A2M, ACVR1, JAG1, ASCL1, BCHE, BCL2, BMP4, BMPR1A, ZFP36L2, RUNX2, COL1A1, DAB2, EDN3, EDNRA, EFNA1, EFNB1, ELAVL1, ERG, ETV4, GATA4, GATA6, GPM6A, HGF, NRG1, HHEX, HIF1A, FOXA2, HES1, RBPJ, ISL1, JARID2, KIT, LAMA5, TACSTD2, EPCAM, SMAD3, SMAD7, KITLG, FOXO4, CNOT2, NRTN, NTF4, PAX3, REST, S100A4, SERPINB3, SDCBP, SEMA3F, SIX3, SNAI1, SOX2, SOX9, SOX10, SOX11, STAT1, TWIST1, WNT2, WNT11, PAX8, SEMA3B, HMGA2, TP63, ADAM15, NRP1, ALDH1A2, PHOX2B, SEMA5A, SEMA3E, CUL7, ZEB2, SEMA3A, MAD2L2, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, SOX21, STRAP |
1804 | GO:0023057 | 0.02 | 1.81 | 21.53 | 30 | 59 | negative regulation of signaling | ACHE, ANXA5, ARF1, BCHE, CD38, CNR2, CRH, DRD5, PTK2B, GHSR, GLRA1, GNAI1, GRIA1, GRIK3, INHA, KCNJ11, PDE4C, PTGS1, REST, SLC18A1, SREBF1, SRF, STXBP1, ABCC8, TNR, UCN, FGF23, DGKI, PICK1, STXBP5L |
1805 | GO:0043123 | 0.00 | 1.80 | 33.25 | 46 | 89 | positive regulation of I-kappaB kinase/NF-kappaB signaling | ABL1, ABL2, BIRC2, BIRC3, BST2, CASP1, CD36, CHUK, CTH, ECM1, LPAR1, F2R, F2RL1, FYN, IL1A, IRAK1, LTF, PARK2, PPM1A, PPP5C, PRKCE, PRKD1, S100A4, S100A12, S100A13, S100B, CCL21, SLC20A1, TNFRSF1A, TRAF2, UBB, TRIM25, IKBKG, TRADD, RIPK1, TNFSF10, RIPK2, TNFRSF10B, CFLAR, LITAF, TRIM13, TRIM22, TRIM38, TRAF3IP2, MALT1, PIM2 |
1806 | GO:0030838 | 0.02 | 1.80 | 20.94 | 29 | 56 | positive regulation of actin filament polymerization | ARF1, ARF6, CTTN, PTK2B, GRB2, HCK, ICAM1, PFN1, PFN2, PRKCE, RAC1, CCL21, CCL24, VIL1, WASF1, PICK1, BAG4, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, ABI2, CDC42EP2, BAIAP2, ARPC1A, CDC42EP3, CORO1A |
1807 | GO:0045921 | 0.02 | 1.80 | 20.94 | 29 | 56 | positive regulation of exocytosis | ARF1, ATP6AP1, CFTR, F2RL1, FCER1G, FGA, FGG, FGR, GLRA1, IFNG, IL13, SEPT5, PTAFR, RAB5A, RAB27A, RAB27B, SDC4, SDCBP, STXBP1, SYT1, TSG101, RAB7A, STAM, VAMP8, SYT7, RAB9A, RAB3D, GAB2, PDCD6IP |
1808 | GO:0032102 | 0.00 | 1.80 | 36.87 | 51 | 99 | negative regulation of response to external stimulus | ABAT, ALOX12, ANGPT2, ANXA5, APOH, BBS2, BBS4, PRDM1, TSPO, SERPING1, CCK, F2, FAP, FGA, FGG, GCG, GP1BA, HMGCR, HRG, IFIT1, KLKB1, KNG1, LTF, SERPINE1, SERPINB2, PCBP2, PPM1B, EIF2AK2, SEC14L1, SEMA3F, ST6GAL1, TNR, TSC1, UCN, USF1, VTN, SEMA3B, NRP1, SEMA5A, FEZ2, SEMA3E, TRIB1, SEMA3A, TRIM38, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, CXCL13, SPINK5 |
1809 | GO:0016101 | 0.02 | 1.80 | 21.69 | 30 | 58 | diterpenoid metabolic process | ABCA4, ADH5, ALDH1A1, ALDH1A3, ALDH3A2, APOA1, OPN1SW, AKR1C4, CLPS, CRH, GPC4, OPN1MW, GPC3, PDE3A, RBP1, RBP2, OPN1LW, RPE65, SDC2, SDC4, SLC12A1, SRD5A1, STAR, AKR1C3, DGAT1, ALDH1A2, DHRS3, SDC3, GPC6, DHRS9 |
1810 | GO:0019216 | 0.01 | 1.80 | 25.30 | 35 | 68 | regulation of lipid metabolic process | ACADL, ACADVL, ATP1A1, BBS4, BRCA1, TSPO, C3, CCNC, DHCR7, DRD3, ESR1, FGFR4, NR5A1, GFI1, FOXA2, INSIG1, PDK4, PSAP, REST, SNAI1, SNCA, SOD1, STAR, STAT5B, STK11, PDHX, IRS4, AKR1C3, EDF1, EIF2AK3, NR1H4, NR1D2, ERLIN1, ERLIN2, DDX20 |
1811 | GO:0030336 | 0.01 | 1.80 | 24.59 | 34 | 66 | negative regulation of cell migration | ADARB1, ALOX15B, ARHGAP4, ARHGDIB, BCL2, BCR, BST2, COL3A1, CX3CR1, DPEP1, DPYSL3, EPHA1, NRG1, SMAD7, PTEN, PTGER4, PTN, PTPRJ, RAP2A, RAP2B, CCL21, CCL25, SRF, STAT3, WNT11, RECK, CHRD, ADAM15, SLC9A3R1, RNF41, CITED2, NRG3, IL24, ABHD2 |
1812 | GO:0055088 | 0.02 | 1.80 | 22.44 | 31 | 60 | lipid homeostasis | ABCA1, ABCA2, ACADL, ACADM, ACADS, ACADSB, ACADVL, APOA1, CAV3, FGFR4, NR5A2, G6PC, GOT1, INS, IVD, LCAT, LIPC, PRKAA1, ACSM3, NR1H2, USF1, ACOX2, ACOX3, SOAT2, DGAT1, LIPG, ABCG1, NR1H4, NR1D2, COL4A3BP, SEC24A |
1813 | GO:0009967 | 0.00 | 1.80 | 69.93 | 97 | 195 | positive regulation of signal transduction | ABAT, ACPP, ACVR1, ACVR2A, ACVR2B, ACVRL1, AKT2, ALOX15B, XIAP, ARHGAP4, ARHGAP6, ARNT, ARNTL, BMP1, BMP3, BMP6, BMP8B, BMPR1A, BMPR2, CD80, CD63, CFTR, CHN1, CHN2, COL1A1, CSNK1D, CSNK1G2, CSNK2A1, CYBA, DAB2, DLX5, DRD3, EMP2, EPS8, EVC, FZD2, GATA4, GATA6, GDF9, GPC3, GPR27, GRB7, HHEX, FOXA2, RBPJ, IHH, ING2, INHA, ITGA5, KCNN4, CD180, CITED1, NTSR1, PRRX1, PTGIS, SALL1, SFRP4, SH3BGR, SH3BGRL, SH3BP2, SHB, SMARCA4, STK11, ADAM17, CNTN2, NR2C1, TTK, VTN, WNT2, WNT2B, ZIC2, STAM, IRS4, CNTNAP1, ITGA8, BUD31, NRXN1, GRAP2, ADAMTS3, GDF15, RIMS2, FGFBP1, HDAC6, SH2B3, FRAT1, SH2D3C, SH2D3A, ATP6AP2, CITED2, VAV3, SORBS1, SH2B2, TRIM16, KHDRBS1, GRAP, GIPC1, ESM1 |
1814 | GO:0032846 | 0.01 | 1.80 | 26.04 | 36 | 70 | positive regulation of homeostatic process | ABAT, ACVR2A, AGTR2, ANXA1, ARNT, ATM, ATP6AP1, ATR, ATRX, AVP, CA2, CCT6A, CNR1, DKC1, DRD3, ERCC1, ETS1, FSHB, IL1B, KNG1, PRKCQ, PTGER4, SLC22A5, SMARCA4, TAC1, TAL1, CCT3, ZNF16, SLC30A2, MAPKAPK5, AURKB, RAD50, CCT7, CCT4, CCT2, SEC24A |
1815 | GO:0009410 | 0.00 | 1.79 | 35.53 | 49 | 95 | response to xenobiotic stimulus | ACY1, ADH1B, ADH5, AHCY, ALDH1A1, ALDH2, ALDH3A1, AOC2, COMT, CRYZ, CYP2A6, CYP2A13, CYP2F1, CYP3A4, CYP8B1, CYP11B1, CYP24A1, CYP51A1, DPEP1, ESD, ACSL1, FDXR, GPX1, GSTM1, GSTM2, GSTZ1, MAT2A, PTGIS, PTGS1, RB1, S100A12, STAR, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, TPMT, SCGB1A1, UGDH, UGP2, UGT2B4, CES2, PAPSS2, PAPSS1, GSTO1, GLYAT, AKR1A1, SLC26A1 |
1816 | GO:1903362 | 0.00 | 1.79 | 65.45 | 90 | 175 | regulation of cellular protein catabolic process | ARAF, ATM, BUB1B, CAV3, CCNB1, CD81, CDC20, CDC27, CDKN2A, CENPF, CLU, CSNK1D, CSNK2A1, CSNK2A2, DAB2, DUSP1, PTK2B, GPX1, UBE2K, DNAJB2, HSP90AB1, SMAD7, PARK2, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, RAD23B, RB1, RDX, SDCBP, SGTA, SKP1, SUMO3, AURKA, TMF1, TNFAIP3, TTK, UBB, UBE3A, SUMO1, WNT1, ZNF207, USP5, CUL3, CUL1, CDC23, CDC16, USP14, RGN, ZW10, PSMF1, BAG5, RNF14, DLGAP5, RNF40, KEAP1, PSMD6, KCNE2, PSME3, PSMD14, TRIB1, ANAPC10, ARIH2, MAD2L2, GIPC1, USP19, UBE2C, GLMN |
1817 | GO:0070302 | 0.00 | 1.79 | 36.28 | 50 | 97 | regulation of stress-activated protein kinase signaling cascade | AMBP, CAV3, CDC42, CTGF, GADD45A, EPHB1, ERCC6, ERN1, F2RL1, PTK2B, FLT4, GPS2, HGF, HMGCR, IGBP1, IGF1R, IL1A, IL1B, MAP3K5, MAP3K11, PRDX1, PARK2, PER1, EIF2AK2, PTPN1, RAP2A, RPS3, SERPINB3, CCL21, SDCBP, TP73, TPD52L1, TRAF2, FZD5, ARHGEF5, FZD4, FZD7, FZD8, RIPK1, RIPK2, HDAC3, TAOK2, TRAF4, ZEB2, STK25, ARL6IP5, ZMYND11, COPS5, MAP4K5, FZD10 |
1818 | GO:0045861 | 0.00 | 1.79 | 86.02 | 118 | 230 | negative regulation of proteolysis | A2M, AHSG, AKT2, AMBP, BIRC2, BIRC3, XIAP, BIRC5, APLP2, APP, ATM, AVP, BST2, BUB1B, SERPING1, C3, SERPINH1, CCNB1, CD44, CD59, CDC20, CDC27, CDKN2A, CENPF, COL4A3, COL6A3, CSNK2A1, CSNK2A2, CST6, DHCR24, DPEP1, DUSP1, ECM1, SERPINB1, F2, GAS1, GAS6, GPC3, SFN, GPX1, SERPIND1, HGF, HRG, DNAJB2, HSP90AB1, IDE, IFI16, IGBP1, IL10, INS, ITIH1, ITIH3, ITIH4, KNG1, CD46, PEBP1, SERPINE1, SERPINB2, SERPINA5, SERPINF1, PI3, SERPINA4, SERPINB5, SERPINB8, SERPINB9, SERPINB10, SERPINB13, SERPINI2, PSEN1, PZP, RAF1, RAG1, RENBP, RPS6KA1, SERPINB3, SERPINB4, SDCBP, SLPI, SNCA, SPINK1, SPINT1, SPOCK1, TRIM21, SERPINA7, TRAF2, TTK, NR1H2, VIL1, VTN, WNT1, ZNF207, PICALM, RECK, CDC23, SERPINB7, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR, CDC16, USP14, ZW10, KLF4, PSMF1, TMEM59, BAG5, HDAC6, ANAPC10, MAD2L2, GIPC1, SPINT3, USP19, PRDX3, SPINK5, UBE2C |
1819 | GO:1902806 | 0.00 | 1.79 | 37.03 | 51 | 99 | regulation of cell cycle G1/S phase transition | ANXA1, ATM, CCND1, BCL2, BID, CDK2, CDKN1A, PRMT2, PIM1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTPN6, RB1, RDX, RPA2, SMARCA4, ADAM17, TP73, UBB, UBE2E2, CUL4A, DGKZ, TP63, CRADD, PSMF1, PSMD6, PSME3, PSMD14, CTDSPL, PDPN |
1820 | GO:0019220 | 0.00 | 1.79 | 33.03 | 46 | 93 | regulation of phosphate metabolic process | APLP2, APOA1, APP, ARR3, BARD1, CCNE1, CCNG1, CDC25A, CDC25C, CDK4, CKS1B, CKS2, EPHA2, EPHB1, HRC, HRG, PRDX1, PGAM1, PGAM2, PPP1R2, PPP2R1B, PPP2R2A, PPP2R5D, RAC2, RAD51, RBL1, RBL2, SET, STYX, HSP90B1, TSC1, TSG101, UVRAG, VRK2, IKBKAP, DIRAS3, CCNE2, EIF2AK3, SMG7, NUAK1, ATP6AP2, RNF41, ARPP19, COPS5, CDC37, AKAP13 |
1821 | GO:1901575 | 0.00 | 1.79 | 57.81 | 80 | 160 | organic substance catabolic process | ACAA1, ACACB, ACADM, ACADS, ACADVL, ACHE, ADH5, ADRB2, AKT2, ABCD1, ALDH2, ALDOB, ALDOC, APOA1, APOH, BAD, BNIP2, DAGLA, CLPS, CNR1, CPT1B, CPT2, CRAT, DECR1, ECH1, ENO2, ENO3, ESD, FAAH, FABP2, FABP6, FABP7, FUT6, FUT8, GALE, GALK1, GAPDH, GK2, GPD2, IDH1, IMPA1, INPP1, KHK, LDHA, LIPE, NTSR1, OXCT1, PAFAH1B2, PAFAH1B3, PAFAH2, PEX7, PEX13, PFKFB1, PFKFB2, PGAM2, PGK1, PPP2R5D, PRKACB, PRKACG, PRKCE, ABCD3, RENBP, RPE, SORD, TWIST1, ACOX2, ACOX3, AKR1C3, SYNJ1, LIPG, PRDX6, XYLB, ACOT8, AKR1A1, ECI2, SLC25A17, FUT9, SLC27A4, SLC27A2, TREH |
1822 | GO:0045786 | 0.03 | 1.79 | 18.07 | 25 | 49 | negative regulation of cell cycle | ALOX15B, CCNF, CDC5L, ETS1, HHEX, NR4A1, HPGD, NUBP1, PRKACB, PRKAR1A, RAD1, SIPA1, SOX11, TAF6, NR2F2, TNFAIP3, ZBTB17, HDAC3, LATS1, SMC3, AURKB, RBM14, CREB3, HEXIM1, STAG2 |
1823 | GO:0014031 | 0.00 | 1.79 | 38.52 | 53 | 103 | mesenchymal cell development | ACVR1, JAG1, BCL2, BMPR1A, COL1A1, DAB2, EDN3, EDNRA, EFNA1, EFNB1, ERG, HGF, NRG1, HIF1A, FOXA2, HES1, RBPJ, ISL1, LAMA5, SMAD3, SMAD7, KITLG, NRTN, PAX3, S100A4, SERPINB3, SDCBP, SEMA3F, SNAI1, SOX9, SOX10, SOX11, TWIST1, WNT2, WNT11, SEMA3B, HMGA2, ADAM15, NRP1, ALDH1A2, PHOX2B, SEMA5A, SEMA3E, CUL7, ZEB2, SEMA3A, MAD2L2, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, STRAP |
1824 | GO:0032874 | 0.01 | 1.79 | 24.68 | 34 | 66 | positive regulation of stress-activated MAPK cascade | CDC42, CTGF, GADD45A, ERCC6, ERN1, F2RL1, PTK2B, FLT4, HMGCR, IL1A, IL1B, MAP3K5, MAP3K11, EIF2AK2, PTPN1, RPS3, CCL21, SDCBP, TPD52L1, TRAF2, FZD5, ARHGEF5, FZD4, FZD7, FZD8, RIPK1, RIPK2, TAOK2, TRAF4, ZEB2, STK25, ARL6IP5, MAP4K5, FZD10 |
1825 | GO:1903649 | 0.03 | 1.78 | 17.38 | 24 | 47 | regulation of cytoplasmic transport | ATP1A2, BCL2, BNIP3L, CASQ1, CASQ2, CYBA, DIAPH1, PTK2B, GAS1, HRC, INSIG1, PARK2, PDE4D, PLN, PRKCE, PRKD1, PTPN6, RYR2, SREBF1, ATG5, BAG4, SEC24B, OS9, CORO1A |
1826 | GO:0051222 | 0.00 | 1.78 | 49.44 | 68 | 133 | positive regulation of protein transport | ACTL6A, AKT2, BMP4, BMPR1A, BRCA1, CAMK4, CDC42, CDH1, CHRM1, CSNK2A2, CTSK, DAB2, EDA, STOM, ERBB2, ACSL3, GAS6, KAT2A, SFN, GPR26, HCLS1, NRG1, HNMT, HES1, HSP90AB1, IL12B, IL18, ITGAX, KPNA1, IPO5, SMAD3, OAZ1, OAZ2, PCM1, PPM1A, PPP3R1, PRKCD, RAC2, RNASE2, SLC9A1, TRIP6, TSG101, U2AF1, UBE2L3, ZIC1, ZBTB17, FZD5, ARHGEF5, BAP1, CAMK1, RUVBL1, TNFSF14, HDAC3, CDKL2, SEMA5A, ITGB1BP1, AKAP6, ATG13, C2CD5, FAM20B, SAE1, NUTF2, PEMT, RAPGEF3, ARIH2, CHERP, RBCK1, EDAR |
1827 | GO:1903034 | 0.00 | 1.78 | 34.14 | 47 | 92 | regulation of response to wounding | A2M, AGTR1, AHSG, BIRC2, BIRC3, XIAP, C3, C7, CASP4, CASP5, CD6, CD28, CD59, CNR1, EDNRA, FFAR3, HCK, IL1B, IL1R1, IL15, IL17A, IL18, IDO1, CD46, NTRK3, OMG, PER1, CFP, PSMA6, PTEN, S100A8, S100A12, CCL24, XCL1, CX3CL1, SELE, STAT5B, XCL2, TAC1, TNFSF4, SCGB1A1, VAMP8, TNFSF18, IL1RL1, CLOCK, NR1D2, TNIP1 |
1828 | GO:0051094 | 0.00 | 1.78 | 47.02 | 65 | 130 | positive regulation of developmental process | AGTR2, ANGPT2, ANXA3, ADGRB1, ADGRB2, CCND1, BMP1, BNIP3, BRCA1, CBLB, CD3E, CD28, CDC20, CDKN2A, CCR3, CTSH, DCN, ECM1, EDNRA, EPHA1, EPHB1, EPHB2, EPHB3, F3, FGF7, FLT1, UTS2R, HMGA1, HSPB1, IL1A, IDO1, ISL1, ITGA5, OTX2, OXTR, P2RX7, SERPINE1, ENPP2, MAPK8, PTGIS, CCL24, SRSF6, STAT6, TNFAIP3, TPBG, UNG, VEGFB, WHSC1, WNT1, ZIC2, HMGA2, FOXN1, SERPINB7, TRADD, ADAM9, NRXN3, NRXN1, EEF1E1, RBM19, RNF10, PDCD6, RAPGEF3, DMRT2, TNFSF13B, SEPT9 |
1829 | GO:0002366 | 0.01 | 1.78 | 29.10 | 40 | 78 | leukocyte activation involved in immune response | ABL1, ANXA1, BCL3, CD28, CD80, CD86, GPR183, ERCC1, PTK2B, HLX, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IL10, IL12B, CD180, CD46, PRKCZ, PSEN1, PTGER4, RAB27A, RARA, RELB, SLC11A1, STAT6, TSC1, TNFSF4, UNG, WHSC1, RIPK2, TNFSF18, RNF8, EXO1, IL27RA, CORO1A |
1830 | GO:0030098 | 0.03 | 1.78 | 18.16 | 25 | 49 | lymphocyte differentiation | ABL2, ZFP36L2, RUNX2, CBFB, CD3D, CD3E, CD4, CD8A, TNFSF8, CDK6, FCER1G, PTGER4, RELB, RPL22, SATB1, SPN, SRF, STAT6, STK11, TSC1, TYRO3, WNT1, FZD5, FZD7, FZD8 |
1831 | GO:0016482 | 0.00 | 1.77 | 136.42 | 186 | 371 | cytoplasmic transport | ADAR, ADRB2, ARL1, ARNTL, RERE, BBS1, BBS2, BID, TSPO, VPS51, CBLB, SCARB2, CD63, CDX2, AP1S1, CSE1L, DDIT3, DNM2, EGR2, EIF4E, EIF5A, EMP2, EPS15, FAU, FYB, GFER, GLE1, GOLGA4, XCR1, HHEX, AGFG1, HSPA4, HSPA8, HSPA9, HSP90AA1, HTR2C, IFNG, ITPR1, ITPR2, JUN, KPNA2, KPNA3, KPNA4, KPNA5, TNPO1, KRT18, CITED1, RPL10A, NUP88, NUP98, OR1D2, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX14, PIK3C3, PEX19, PEX5, RAB5A, RAB5B, RAB6A, RAB13, RAB5C, RAN, RANBP2, UPF1, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, RYR3, SORT1, CCL21, SET, SRSF1, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SIX3, SLC8A3, SLC11A1, SRP9, SRP14, SRP19, SRP68, SSR1, STAT3, STYX, TRPM2, TSC1, TSC2, TSG101, TST, TRPV1, RAB7A, NUP214, ANP32A, CLTCL1, EEA1, AP3B1, BLZF1, AKR1C3, STX16, STX10, BECN1, SRSF9, RAB11A, AP1M1, AP3D1, TRPA1, RPL14, AP4M1, TRIP11, RPL23, RAB9A, ZFYVE9, PEX16, VPS26A, NUP155, IPO13, NUP93, GPRASP1, ZFYVE16, SNX17, TOMM20, ZC3H11A, SMG7, SGSM2, RBM8A, DOPEY2, ACTR2, ARFRP1, DDX39A, NXF1, ARFGEF2, TXNIP, AHCYL1, VAMP5, RAB10, MALT1, RNPS1, AFG3L2, TOMM34, RAB32, RAB31, NUPL2, AKAP13, RPL35, SEC63 |
1832 | GO:0006461 | 0.00 | 1.77 | 57.50 | 79 | 158 | protein complex assembly | BIRC5, ATRX, BAD, BLK, CCNB1, CD3G, CDC42, CLGN, CHD4, COL16A1, CYLD, EIF4EBP1, EPRS, FANCA, FANCC, CENPI, GFAP, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, HIST1H1A, HMGA1, HRG, HES1, HSPA8, IL1RAP, KPNA3, OTX2, CHMP1A, PPID, PPP2R1A, PPP2R1B, PTGER4, RAF1, SELP, SET, SH3BGR, SLC2A1, SOX9, AURKA, STK11, TNFRSF1A, TRAF1, CCT3, TSPY1, ZNF148, CHAF1B, HIST1H2BG, HIST1H2BL, HIST1H2BN, HIST1H2BM, HIST1H2BO, HIST2H2BE, SMARCA5, IKBKAP, HAT1, CDC14A, RUVBL1, RAB11A, LIN7A, HDAC3, HIST1H2BJ, H1FX, ZW10, REPS2, AURKB, ITGB1BP1, SLC9A3R2, SLC9A3R1, KIF3B, NRXN1, FARP2, PPIH, AFG3L2, FERMT2, SLC7A9, CHEK2 |
1833 | GO:0048167 | 0.04 | 1.77 | 16.04 | 22 | 43 | regulation of synaptic plasticity | ATP2B2, CAMK2A, CDC20, CTNND2, EGR2, HRH1, HRH2, KCNJ10, KIT, KRAS, P2RX3, PSEN1, RARA, STAR, SYP, CNTN2, RAB11A, RIN1, RAPGEF2, BAIAP2, GIPC1, CPLX2 |
1834 | GO:0001817 | 0.01 | 1.76 | 26.98 | 37 | 73 | regulation of cytokine production | ADRA2A, BIRC2, BIRC3, ARNT, ATF4, BRCA1, C3, CD6, CREB1, ATF2, DDIT3, FLT4, GATA4, HIF1A, IL12RB2, IL15, IL18, LUM, CD46, P2RY2, SERPINE1, PDE4B, PDE4D, PER1, EIF2AK2, SEC14L1, SOD1, ADAM17, TMF1, UCN, SERPINB7, TNFSF9, EIF2AK3, IL27RA, LITAF, ATP6AP2, HHLA2 |
1835 | GO:0016331 | 0.01 | 1.76 | 33.66 | 46 | 90 | morphogenesis of embryonic epithelium | ADM, ALDH1A3, APAF1, BBS4, BMP4, FZD2, KAT2A, ARHGAP35, GRSF1, HHEX, HIF1A, LAMA5, LLGL2, OPA1, PAX3, PCDH8, PFN1, PRKACB, RALA, RARA, SALL1, SDC4, STIL, SIX1, SOX9, SOX11, SPINT1, ST14, TSC1, TSC2, TULP3, TWIST1, KDM6A, VEGFC, WNT2, WNT2B, ZIC2, PAX8, FZD6, TP63, ALDH1A2, HAND1, ZEB2, SEC24B, DEAF1, GLMN |
1836 | GO:0021953 | 0.00 | 1.76 | 34.41 | 47 | 92 | central nervous system neuron differentiation | PHOX2A, ASCL1, ATP2B2, CACNA1A, CHRNB2, CSF1R, DCC, DCX, EMX1, EPHB1, EPHB3, EVX1, GNAQ, GRID2, HOXC10, HOXD10, HPRT1, HES1, ISL1, NTRK2, OGDH, PAX3, PSEN1, PTEN, PTK2, RAC1, RAC3, RYK, SALL1, SMARCC2, SOX1, SOX2, SPOCK1, TAL1, CNTN2, TULP3, UBB, WNT1, NRP1, PHOX2B, SLIT2, NRXN1, RAPGEF2, OLIG2, SEMA3A, ATG7, TBR1 |
1837 | GO:0030071 | 0.05 | 1.76 | 16.08 | 22 | 43 | regulation of mitotic metaphase/anaphase transition | ATM, BUB1B, CCNB1, CDC20, CDC27, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, PTEN, RB1, TTK, ZNF207, CUL3, CDC23, CDC16, ZW10, DLGAP5, ANAPC10, MAD2L2, UBE2C |
1838 | GO:0061333 | 0.05 | 1.76 | 16.08 | 22 | 43 | renal tubule morphogenesis | AGTR2, BCL2, BMP4, CD44, EYA1, GPC3, HOXD11, HES1, ILK, LAMA5, TACSTD2, CITED1, PBX1, PSPN, SALL1, SIX1, SOX9, WNT1, WNT11, WNT2B, PAX8, DCHS1 |
1839 | GO:0035264 | 0.03 | 1.76 | 18.27 | 25 | 49 | multicellular organism growth | ADD1, ATRX, BRCA2, CDC42, DHCR7, EN1, ERCC1, ERCC6, G6PC, KAT2A, GPD2, HHEX, IHH, LLGL2, PDE4D, RARA, RARB, RBBP6, STIL, SLC12A2, TAL2, KDM6A, XPA, XRCC2, KLF2 |
1840 | GO:0097193 | 0.02 | 1.75 | 24.12 | 33 | 65 | intrinsic apoptotic signaling pathway | XIAP, BDKRB2, BNIP3, CYLD, DDX5, E2F2, GCG, GPX1, HIF1A, HSPB1, INS, PPP3R1, PRKCD, MAPK8, SCN2A, SOD2, STK11, VDAC2, YWHAZ, CUL4A, CUL3, CUL2, CUL1, DYNLL1, URI1, ARHGEF2, BAG5, TRAP1, STK25, ARL6IP5, SIVA1, IVNS1ABP, YWHAQ |
1841 | GO:0044784 | 0.04 | 1.75 | 16.83 | 23 | 45 | metaphase/anaphase transition of cell cycle | ATM, BUB1B, CCNB1, CDC20, CDC27, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, PTEN, RB1, TTK, ZNF207, CUL3, CDC23, CDC16, ZW10, DLGAP5, ANAPC10, MAD2L2, UBE2C, CIT |
1842 | GO:0000086 | 0.00 | 1.75 | 39.59 | 54 | 106 | G2/M transition of mitotic cell cycle | BIRC5, ATM, BACH1, CCNB1, CCNH, CDC25A, CDC25C, CDK2, CDKN1A, CDKN2A, CENPF, CHEK1, CSNK1D, GADD45A, DYNC1H1, DYNC1I2, DNM2, EP300, HSP90AA1, FOXO4, PPP1R12A, PPP1R12B, NUMA1, PCM1, CDK14, PPP2R1A, PPP2R2A, PRKAR2B, PRKCQ, SKP1, AURKA, TAF2, TPD52L1, TUBA4A, TUBG1, UBB, WEE1, ALMS1, TUBA1A, HMGA2, CUL1, PPM1D, SSNA1, DYNLL1, LATS1, CCNB2, CEP135, CKAP5, AKAP9, TUBGCP3, KHDRBS1, ARPP19, TUBGCP2, CHEK2 |
1843 | GO:0030111 | 0.00 | 1.75 | 63.21 | 86 | 169 | regulation of Wnt signaling pathway | ABL1, ABL2, XIAP, ARNTL, CCND1, COL1A1, CSNK1D, CSNK1G2, CSNK2A1, CTNND2, CYLD, DAB2, DAPK3, DDIT3, DLX5, EDA, FGFR3, FZD2, RAPGEF1, HHEX, HIC1, IGFBP2, IGFBP6, RBPJ, ILK, ISL1, ITGA3, SMAD3, CITED1, PARK2, CDK14, PPM1A, PPP2R1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, SALL1, SFRP4, SFRP5, SIX3, SMARCA4, SOX2, SOX9, SOX10, STK11, TSC2, UBB, WNT1, WNT2, WNT11, WNT2B, FZD5, FZD6, CUL3, RGS20, LATS1, PSMF1, ZEB2, PSMD6, RBX1, FRAT1, G3BP1, ATP6AP2, PSME3, PSMD14, APC2, MAD2L2 |
1844 | GO:0042278 | 0.00 | 1.75 | 63.96 | 87 | 171 | purine nucleoside metabolic process | ACACB, ACPP, ADSL, ADSS, AHCY, AK1, AK2, AK4, ALDOB, ALDOC, AMPD2, APRT, ARNT, ATP1A2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V0A1, ATP5O, BAD, TSPO, COX4I1, COX8A, COX15, CTNS, DLG2, DLG3, DNMT1, DNMT3B, ENO2, ENO3, GAMT, GAPDH, GPD1, HIF1A, HMGCR, HPRT1, HSPA8, IGF1, IMPDH1, IMPDH2, INS, LDHA, LDHC, MAT2A, OGDH, P2RX7, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PGM1, PPP2R5D, PRKAA1, PRKAG1, PTGDR, SDHC, SNCA, STAT3, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, TAZ, UQCRC1, UQCRC2, UQCRH, OGT, PAPSS2, PAPSS1, ATP5J2, HDAC4, SLC25A13, PEMT, ATP5H, ATP5L, AHCYL1, SLC26A1 |
1845 | GO:0033047 | 0.04 | 1.75 | 18.33 | 25 | 49 | regulation of mitotic sister chromatid segregation | ATM, ATRX, BUB1B, CCNB1, CDC20, CDC27, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, PTEN, RB1, TTK, ZNF207, CUL3, BECN1, CDC23, CDC16, ZW10, DLGAP5, ANAPC10, MAD2L2, UBE2C, CIT |
1846 | GO:0044728 | 0.04 | 1.75 | 18.33 | 25 | 49 | DNA methylation or demethylation | ATRX, BRCA1, DNMT1, DNMT3B, GNAS, MGMT, HIST1H4I, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, FKBP6, ALKBH1, HIST1H3F, PICK1, CTCF |
1847 | GO:0006897 | 0.00 | 1.75 | 46.18 | 63 | 125 | endocytosis | ABCA1, ACTB, ACTG1, ANXA1, ANXA3, ANXA11, APLP1, APP, ARR3, BCL2L1, CD3G, CDC42, CEBPE, CLCN3, CLCN5, CRP, FCGR1A, FCN2, FYN, HSP90AB1, INPPL1, ITPR1, ITPR2, LIMK1, P2RX7, PIK3C3, PRKCD, PRKCE, PTK2, RAB1A, RARA, SORT1, SYP, ICAM5, TYRO3, UBE3A, VAV1, RAB7A, SRPX, EEA1, BECN1, RABEP1, TRIP10, ZFYVE9, RIN1, CLINT1, ELMO1, ABI1, TOM1, ATP9A, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, WASF2, SPON2, VAV3, BAIAP2, ARPC1A, USP20, CORO1A |
1848 | GO:0019221 | 0.00 | 1.75 | 50.52 | 69 | 138 | cytokine-mediated signaling pathway | ANGPT1, BAD, BBS2, BBS4, CHAD, CISH, CNTF, CSF1R, CSF2RB, DCN, ECM1, EIF4A1, EIF4E, EIF4G1, EIF4G2, EREG, F3, ACSL1, FLT3, GP1BA, IFNW1, IL1A, IL1B, IL1R1, IL1RAP, IL1RN, IL2RA, IL10RA, IL12B, IL12RB2, IL13RA2, IL15RA, IRAK1, IRAK2, KIT, KPNA1, KPNA2, KPNA3, KPNA4, KPNA5, KRAS, NUP88, NUP98, PPM1B, PTPRN, RANBP2, STAT3, STAT4, STAT5B, STAT6, UBA7, VRK2, PXDN, IL1R2, NUP214, AAAS, EIF4G3, RPS6KA4, RQCD1, IL1RL1, NUMBL, SOCS6, IL27RA, NUP155, CTR9, NUP93, EIF4A3, NUP50, NUPL2 |
1849 | GO:0051093 | 0.02 | 1.74 | 21.18 | 29 | 58 | negative regulation of developmental process | AHSG, ARHGDIB, BCR, BNIP3, BRCA2, CD86, CDH3, CHAD, TSC22D3, ECM1, ETV4, FGF3, NR5A1, GAS6, HIF1A, TNFRSF11B, PARK2, PRKACB, SFRP5, SIX1, STK11, TULP3, USP2, RGN, CER1, EIF2AK3, FIG4, RAPGEF3, USP19 |
1850 | GO:0051649 | 0.00 | 1.74 | 319.91 | 426 | 886 | establishment of localization in cell | ABCA2, ACACB, ACTL6A, ADAR, ADRB2, AKT2, ABCD1, BIRC5, ARL1, ATM, RERE, ATP1A2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP5O, ATP7B, KIF1A, BARD1, BBS1, BCL2L1, BCL3, BGLAP, BICD1, BMP4, BMPR1A, BNIP3, BNIP3L, BRCA1, BRCA2, BSG, BST2, TSPO, VPS51, CAMK4, CASQ1, CASQ2, CBLB, CCNB1, CD4, SCARB2, CDC42, CDH1, CDKN1A, CDKN2A, CDX2, CENPA, CENPE, CENPF, CHRM1, AP1S1, AP2S1, CLCN3, CLTA, CCR5, CNP, CPT1B, CPT2, ATF2, CSE1L, CSNK2A2, CTSK, CYBA, CYLD, DAB2, DDIT3, DIAPH1, DYNC1H1, DYNC1I2, EDA, EDNRA, EGR2, EIF4E, EIF5A, EMP2, CTTN, STOM, EPS15, ERBB2, EYA1, EYA2, F2, F7, F10, ACSL3, PTK2B, FAU, FTL, FYB, GAS1, KAT2A, GDI1, GFER, GLE1, GNAQ, GOLGA3, GOLGA4, GOLGB1, XCR1, GPR26, GSTM2, HCLS1, NRG1, HHEX, HNMT, AGFG1, HRC, HES1, HSPA4, HSPA9, HSP90AA1, HSP90AB1, IFIT1, IL12B, IL18, INSIG1, ITGAX, ITGB1, JUN, KCNE1, KCNJ10, KIF5A, KLC1, KPNA1, KPNA2, KPNA3, KPNA4, KPNA5, TNPO1, IPO5, KRT18, SMAD3, MYO1B, CITED1, PPP1R12A, RPL10A, TONSL, NUMA1, NUP88, NUP98, OAZ1, OAZ2, OGG1, OPA1, OR1D2, P2RX3, P2RX4, P2RX5, PRDX1, PALM, PCM1, CHMP1A, PDE4D, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX14, PLN, PPM1A, PPM1B, PRKCD, PRKCI, PRKD1, PROC, PTK2, PTPN1, PTPN6, PEX19, PEX5, RAB5B, RAB6A, RAB5C, RAN, RANBP1, RANBP2, RANGAP1, RB1, RBM4, RDX, UPF1, RNASE2, RPGR, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, CLIP1, RTN2, RYR1, RYR2, RYR3, SORT1, CCL21, XCL1, SEL1L, SET, SFRP5, SRSF1, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SIX3, SLC8A3, SLC9A1, SLC11A1, SLN, SP100, SPAST, SRP9, SRP14, SRP19, SRP68, SSR1, STAR, STAT3, STYX, DYNLT1, TNNC1, TNNT2, HSP90B1, TRIP6, TRPC1, TRPC3, TSC1, TSC2, TST, U2AF1, UBB, UBE2L3, UCP1, UVRAG, ZIC1, ZBTB17, ZP2, ALMS1, TUBA1A, FZD5, NUP214, AAAS, ANP32A, AKAP1, CLTCL1, PICALM, BAP1, FZD7, UXT, EEA1, DYRK2, OGT, CAMK1, BLZF1, RGS20, SLC25A12, RUVBL1, SSNA1, AKR1C3, STX16, STX10, BECN1, SRSF9, CDC23, TNFSF14, INPP4B, HDAC3, PROZ, AP1S2, AP1M1, HERC2, TRPA1, CDKL2, SEMA5A, RPL14, SEC22C, AP4M1, ARHGEF2, RASSF9, ZW10, VAPB, CYTH3, ITGB1BP1, TRIP11, TAOK2, RPL23, SLC9A3R1, ZFYVE9, COG1, PEX16, GSTO1, PICK1, AKAP6, LITAF, BAG4, ATP5J2, VPS26A, AKAP12, ABCG1, NUP155, IPO13, CLINT1, NUP93, GPRASP1, IFT140, ZFYVE16, ATG13, SNX17, DLGAP5, TOMM20, KEAP1, DNAJC6, C2CD5, ZC3H11A, SMG7, SGSM2, FAM20B, RBM8A, GOLGA5, DOPEY2, HDAC6, PDCD6, TOM1L1, TOM1, SAE1, ATP9A, COL4A3BP, ACTR2, ARL4C, ARFRP1, SLC25A13, SLC25A15, NUTF2, DDX39A, SPRY1, STAM2, RAMP2, RAMP3, APC2, KATNB1, TRDN, ATP8A1, PEMT, ARIH2, ACAA2, TACC3, COG5, ATP5H, NXF1, SEC23B, CREB3, STK25, APPBP2, CHERP, SIVA1, RBCK1, TXNIP, ATP5L, KHDRBS1, DCTN6, KIF1C, NUP50, AHCYL1, VAMP5, RAB10, MALT1, EDAR, RNPS1, AFG3L2, KDELR1, SEC61B, TOMM34, OS9, RAB32, KIF2C, KDELR2, IFT27, RAB35, RER1, NUPL2, ZWINT, CDC37, BVES, AP4S1, NUDT4, AKAP13, RPL35, SEC63 |
1851 | GO:0021510 | 0.03 | 1.74 | 20.57 | 28 | 55 | spinal cord development | ACTL6A, PHOX2A, ASCL1, CACNA1A, DCC, EVX1, GLRA2, HOXC10, HOXD10, ISL1, PAX3, RELN, PTN, PTPRS, SOX1, SOX11, SOX12, SRD5A1, TAL1, TULP3, WNT1, ZIC1, CHRD, EED, SLIT2, BAG3, OLIG2, RAPGEF3 |
1852 | GO:0010921 | 0.02 | 1.73 | 23.56 | 32 | 63 | regulation of phosphatase activity | AGTR2, CALM1, CALM3, CRY2, DLG2, DLG3, GPLD1, IFNG, IGBP1, ITGA1, SMAD3, PPP1R12A, PAWR, PPP1R2, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, EIF2AK2, SET, HSP90B1, TSC1, URI1, RGN, AKAP6, BAG4, PPP1R26, NUAK1, FARP1, CD2BP2, SEMA4D, ARPP19 |
1853 | GO:0002064 | 0.01 | 1.73 | 30.93 | 42 | 83 | epithelial cell development | JAG1, ARNTL, ATP2B2, ATRX, BAD, PRDM1, BMP4, BMP6, KLF5, CDC42, CDK6, CLDN3, DNASE1L2, E2F4, ESR1, B4GALT1, SFN, ONECUT1, HRH2, IHH, CITED1, NTRK1, RAB13, RAC1, RARA, RARB, RHEB, SALL1, SOD1, SOX9, ST14, STAT1, CLRN1, PAX8, FZD7, TP63, SLC9A3R1, ONECUT2, SLC4A7, CLOCK, AKAP9, SEC24B |
1854 | GO:0032271 | 0.01 | 1.73 | 27.25 | 37 | 73 | regulation of protein polymerization | ABL1, ARF1, ARF6, ARL2, CAV3, CTTN, PTK2B, GRB2, HCK, HCLS1, ICAM1, PRKCE, RAC1, RGS2, RPS3, CLIP1, CCL21, CCL24, WASF1, LATS1, PICK1, BAG4, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, ABI2, TUBGCP3, CDC42EP2, BAIAP2, ARPC1A, CDC42EP3, TUBGCP2, TPPP, CORO1A |
1855 | GO:0010628 | 0.00 | 1.73 | 52.75 | 72 | 147 | positive regulation of gene expression | ACTG2, ADAR, ALOX12, AVP, AVPR2, PRDM1, C3, CCNB1, CD3E, CD44, CDC42, CDH3, CDK4, CDK6, CIRBP, CNTF, CRH, CRP, CTGF, CTSH, DAZ1, DNMT1, DNMT3B, EEF2, EIF5A, ELAVL1, ERN1, PTK2B, FBLN1, FGFR4, GAS6, HMX2, HOXD3, HSPA8, IL18, ITGA3, KLKB1, CD46, NTRK2, NTRK3, P2RX7, SERPINB9, PIK3CB, PRKAA1, PRKAG1, MAPK8, PTAFR, PTGER4, RAB27A, RDX, RPS4X, RPS6KB1, RPS6KB2, SFRP4, SNRNP70, SRPK2, STAR, CNTN2, CLEC3B, KDM6A, VIM, ZFP36, ALDH1A2, EIF2B5, QKI, RIMS2, EIF4A3, SF3B4, RAMP2, PIAS3, KHDRBS1, EDAR |
1856 | GO:0001933 | 0.01 | 1.73 | 30.95 | 42 | 83 | negative regulation of protein phosphorylation | AMBP, ANGPT1, BAX, BDKRB2, CALM1, CALM3, CCNB1, CRYBA1, F2RL1, FBLN1, GFRA2, RAPGEF1, IGBP1, IGF1, IGFBP3, JUN, SMAD3, SMAD6, SMAD7, NTF3, NTRK3, P2RX7, PARK2, PDE4D, PER1, PPP5C, PRKCZ, PTPRR, SNCA, SPINK1, TWIST1, OGT, HDAC3, KLF4, SLIT2, SLC9A3R1, RANBP9, CTDSPL, TNIP1, SEMA4D, ZMYND11, STRAP |
1857 | GO:0048489 | 0.02 | 1.73 | 25.06 | 34 | 67 | synaptic vesicle transport | AMPH, ARF1, CACNA1A, CANX, DNM1, DNM2, BLOC1S1, GRN, P2RX7, PARK2, PFN2, SEPT5, PSEN1, RAB5A, RAB27A, SNAP25, SNCA, STXBP1, SYN1, SYT1, SYT5, DOC2A, AP3B1, CADPS, STX11, LIN7A, SYNJ1, AP3D1, SNAP29, RIMS2, SNPH, CPLX2, CPLX1, AP3M2 |
1858 | GO:0051250 | 0.02 | 1.73 | 25.06 | 34 | 67 | negative regulation of lymphocyte activation | ANXA1, ATM, AXL, PRDM1, BMP4, CBLB, CDKN2A, CTLA4, CYLD, ERBB2, FLT3, HLX, IFNA2, IHH, IL2RA, IL10, IDO1, INHA, IRF1, PAWR, PRKAR1A, PTPN6, XCL1, SFTPD, SOX11, SPN, TNFAIP3, TNFSF4, TYRO3, SCGB1A1, PDE5A, TNFSF18, SOCS6, GLMN |
1859 | GO:0051640 | 0.00 | 1.73 | 100.89 | 136 | 270 | organelle localization | ALB, AMPH, BIRC5, ARCN1, AREG, ARF1, ATM, ATP2A1, ATP6AP1, BBS2, BBS4, BICD1, BRCA2, CACNA1A, CANX, CAV3, CCNB1, CD59, CDH3, CENPA, CENPE, CENPF, COPA, CSNK1D, CTSZ, DNM1, DYNC1H1, DYNC1I1, DNM2, EYA1, FCER1G, FGR, BLOC1S1, KAT2A, GOLGA2, GRIA1, GRN, HHEX, HIF1A, IL13, IL13RA2, ITGA4, KIT, LLGL2, LMAN1, LRMP, MAP6, NUBP1, NUMA1, NUP88, OPA1, P2RX7, PARK2, PCM1, CHMP1A, PEX1, PEX13, PEX14, PFN2, SEPT5, PPP6C, PRKCZ, PSEN1, PTEN, PTK2, RAB1A, RAB5A, RAB6A, RAB27A, RAB27B, RAC2, RAN, RB1, S100A13, TRAPPC2, SNAP25, SNCA, AURKA, STXBP1, STXBP2, SYN1, SYT1, SYT5, TACC1, DYNLT1, TRAPPC10, UBB, LAT2, UXT, DOC2A, CUL3, OGT, IKBKG, AP3B1, USO1, CADPS, VAMP8, STX11, BECN1, CDC23, RAB11A, LIN7A, SYNJ1, AP3D1, ARHGEF2, ZW10, COPB2, SNAP29, KIF3B, NRXN1, GOSR1, SEC22B, GOSR2, CROCC, RIMS2, SNPH, DLGAP5, GAB2, HDAC6, AP1M2, ACTR2, PREB, SPRY1, KATNB1, SEC24B, TACC3, SEC23A, TACC2, YKT6, SEC24A, CPLX2, CPLX1, AP3M2, TMED2, KIF2C, KIF3A |
1860 | GO:0006023 | 0.01 | 1.73 | 27.30 | 37 | 73 | aminoglycan biosynthetic process | ANGPT1, VCAN, CSPG4, DCN, EXT1, EXT2, EXTL1, EXTL3, GPC4, B4GALT1, GPC3, HEXA, IGF1, IL1B, LUM, CHST6, OMD, OGN, PTGER4, SDC2, SDC4, UGDH, B4GALT4, B4GALT3, B4GALT6, B4GALT5, CHST3, HS2ST1, SDC3, HS3ST3B1, HS3ST3A1, HS3ST1, ABCC5, GPC6, B3GNT3, SLC35D2, KERA |
1861 | GO:0045596 | 0.00 | 1.73 | 50.13 | 68 | 136 | negative regulation of cell differentiation | ABCA1, NR0B1, ANXA1, APCS, AREG, ARNTL, ZFP36L2, C1QC, RUNX1T1, CDK6, CDKN2A, COL5A2, CRP, CTLA4, CYLD, ERBB2, PTK2B, FLT3, GABPA, HLX, IAPP, IFNA2, IGFBP5, RBPJ, IHH, INHA, INSIG1, IRF1, ITGAV, KRAS, SMAD3, PF4, PTHLH, RARA, RARB, SORT1, S100B, SNAI1, STAT5B, TWIST1, TNFSF4, NR1H2, USH2A, WNT1, FGF23, HIST1H4I, FZD7, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, CHRD, INPP4B, TNFSF18, GPR55, ABCG1, CTR9, TRIB1, LRRC17, FSTL3, GAS2L1, TOB2, CCDC85B, ADAMTS7 |
1862 | GO:0032107 | 0.01 | 1.73 | 28.80 | 39 | 77 | regulation of response to nutrient levels | ACTL6A, ADRB2, ATP6V0A1, BBS2, BBS4, BNIP3, BNIP3L, TSPO, CCK, CSNK2A2, CTSK, DCN, CTTN, ERN1, GCG, KAT2A, GHSR, HIF1A, KDR, PAFAH1B2, PARK2, PIP4K2A, SREBF1, TSC1, U2AF1, UCN, ZBTB17, FZD5, RAB7A, EPM2A, RUVBL1, BECN1, TRIM24, RAB33A, ATG5, FEZ2, HDAC6, TRIM13, ATG7 |
1863 | GO:0002684 | 0.00 | 1.73 | 36.00 | 49 | 99 | positive regulation of immune system process | ACVR2A, JAG1, ARNT, ATP6AP1, AXL, BAD, PRDM1, CA2, CD5, CD6, CD81, CDKN1A, CHRNB2, CSF1R, DPP4, GPR183, EFNB1, EGR3, ETS1, FLOT2, FLT3LG, GNAS, HCLS1, HIF1A, HES1, IGF1, IGF2, IGFBP2, IHH, IL2RA, IL17A, IL18, RAG1, RB1, SPN, TAC1, TAL1, KLF10, VCAM1, ZNF16, OGT, AP3B1, TNFSF9, AP3D1, IL1RL1, TRIB1, IKZF1, HHLA2, CORO1A |
1864 | GO:0050688 | 0.01 | 1.72 | 35.46 | 48 | 95 | regulation of defense response to virus | ANXA5, BIRC2, BIRC3, CD37, COX8A, CLDN7, EIF2S1, STOM, FCGR3B, FGF7, SLC37A4, GABRA5, IFIT1, IL2RA, IL12B, IL15, KCNQ1, MDH1, NTHL1, PCBP2, PDK4, PEX13, SERPINB10, PPM1B, SCN1A, SEC14L1, SLC1A3, SNRPD1, SPN, STAT2, TNFAIP3, ZNF189, CHAF1B, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H3F, CHST3, NUP93, PHYHIP, IST1, FGFBP1, TRIM38, CREB3, TRAF3IP2 |
1865 | GO:1902580 | 0.00 | 1.72 | 191.37 | 256 | 518 | single-organism cellular localization | ACTL6A, AKT2, ALB, ARCN1, AREG, ARF6, ASNA1, ATM, ATP1B3, ATP2A1, BAD, BAX, BBS1, BBS2, BBS4, BCL2, BCL2L1, BICD1, BID, BNIP3L, BRCA2, BSG, TSPO, CALCR, CAV3, CCNB1, SCARB2, CD59, CDC42, CDH3, CDKN2A, CENPA, CENPE, COPA, CSNK1D, CSNK2A2, CTSK, CTSZ, DLG2, DLG3, DYNC1H1, DYNC1I1, DPP6, EPHA2, EMP2, STOM, ERBB2, ETV5, EYA1, ACSL3, FAU, FCER1G, FGR, FLOT2, KAT2A, GDI1, GFER, GOLGA2, GOLGA4, SFN, GPR26, GRIA1, NRG1, HIF1A, HNMT, HSPA4, HSPA8, HSPA9, HSP90AA1, IL13, IL13RA2, INSIG1, ITGA3, ITGA4, ITGAX, ITGB1, KCNE1, KIT, KRT18, LAMA5, LLGL2, LMAN1, MAL, RPL10A, NUMA1, OPA1, P2RY1, PALM, CHMP1A, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX14, PIGR, PPP6C, PRKCI, PRKCZ, MAPK8, RELN, PTEN, PTN, PEX19, PEX5, RAB1A, RAB6A, RAB13, RAB27B, RAC1, RAC2, RAP2A, RB1, RDX, RNASE2, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, CLIP1, S100A10, S100A13, SDCBP, TRAPPC2, SLC12A1, SREBF1, SRP9, SRP14, SRP19, SRP68, SSR1, STXBP2, DYNLT1, TRAPPC10, TNFRSF1A, TUB, TULP1, TULP2, TULP3, U2AF1, UBB, UBE2L3, SUMO1, UVRAG, VIL1, LAT2, WRB, YWHAZ, ZBTB17, FZD5, RAB7A, MADCAM1, UBL4A, BAP1, UXT, CUL3, OGT, BLZF1, RUVBL1, USO1, SSNA1, NUMB, DYNLL1, VAMP8, BECN1, CDC23, RAB11A, CDKL2, RPL14, ARHGEF2, ZW10, VAPB, ITGB1BP1, COPB2, TRIP11, TAOK2, KIF3B, NRXN1, NRXN2, PEX16, CRIPT, PICK1, TMEM59, BAG4, SEC22B, GOSR2, RAPGEF2, ZFYVE16, ATG13, DLGAP5, TOMM20, GAB2, C2CD5, FAM20B, BCL2L11, SAE1, ACTR2, PREB, ARFRP1, SPRY1, RAMP2, RAMP3, KATNB1, ATP8A1, PEMT, ARIH2, SEC24B, SEC23A, SORBS1, VAMP5, SEC24A, RAB10, AFG3L2, TOMM34, TMED2, YWHAQ, FERMT2, KIF2C, RAB31, RER1, KIF3A, RPL35, SEC63 |
1866 | GO:0015672 | 0.00 | 1.72 | 86.06 | 116 | 232 | monovalent inorganic cation transport | ABAT, ACACB, ARF1, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, ATP5O, CACNA1A, CD63, CHRNB2, CNR1, COX4I1, COX5B, COX6A1, COX6B1, COX7A1, COX7C, COX8A, COX15, CPT1B, CPT2, CRH, CYB5A, DRD3, EDNRA, STOM, FCER1G, IL13, SLC11A2, P2RX1, P2RX4, P2RX7, PARK2, PCP4, PER1, FXYD3, PRKCE, PSEN1, RAB3B, RHAG, RHCE, RHD, SCN1A, SCN2A, SCN3A, SCN4B, SCN5A, SCN7A, SCN8A, SCN10A, SCNN1A, SCNN1B, SCNN1G, SEC14L1, SGK1, SLC5A2, SLC5A3, SLC5A5, SLC8A3, SLC9A1, SLC9A2, SLC9A3, SLC9A5, SLC10A1, SLC10A2, SLC12A3, SLC13A1, SLC15A1, SLC15A2, SLC34A1, SLC18A1, SLC20A1, SLC22A1, SLC22A3, SLC22A2, SLC22A5, SNCA, TAF7, TRAPPC10, TRPM2, TWIST1, UCP1, UQCRC1, UQCRH, SLC4A4, VAMP8, SLC5A6, SLC13A2, ATP6V0D1, COX7A2L, SLC24A1, SLC33A1, SLC9A3R1, SLC4A7, SLC4A8, ATP6V1G1, ATP5J2, SGK2, ATP5H, SLC9A6, SLC35A1, SLC34A2, ATP5L, AHCYL1, UQCR11 |
1867 | GO:0031330 | 0.00 | 1.72 | 40.02 | 54 | 107 | negative regulation of cellular catabolic process | ACACB, ADRA1B, ATM, BCL2, BCL2L1, BUB1B, TSPO, CCNB1, CDC20, CDC27, CDKN2A, CENPF, CNR1, CSNK2A1, CSNK2A2, DFFA, DUSP1, GATA4, GOLGA2, GPLD1, HGF, HP, HSP90AB1, IL10, INS, KIF25, PSEN1, SDCBP, SNCA, SNRNP70, STAT3, TSC1, TTK, WNT1, ZNF207, CDC23, CDC16, USP14, RGN, ZW10, PSMF1, BAG5, FEZ2, KDM4A, DHX34, HDAC4, ANAPC10, MAD2L2, ATG7, RRAGA, GIPC1, USP19, UBE2C, WDR6 |
1868 | GO:0051224 | 0.00 | 1.72 | 40.02 | 54 | 107 | negative regulation of protein transport | ADRA2A, ANGPT1, ANXA1, ANXA5, APOA1, BARD1, CD36, CYLD, DRD3, F2R, F2RL1, FBLN1, GAS6, GDI1, GHSR, HMGCR, IFNA2, IL1B, IL10, INS, KCNE1, KCNJ11, TONSL, PARK2, PDE4C, PPM1A, PPM1B, PTGER4, RANGAP1, REST, CX3CL1, SFRP5, SP100, SREBF1, ABCC8, TRIP6, TNFSF4, TNFRSF4, AKAP1, DYRK2, OGT, TNFSF14, ITGB1BP1, SLC9A3R1, STXBP5L, LITAF, BAG4, KEAP1, NR1H4, APC2, TACC3, CREB3, OS9, WWP2 |
1869 | GO:0032787 | 0.05 | 1.71 | 16.98 | 23 | 46 | monocarboxylic acid metabolic process | AMT, BCKDHA, BTD, DBT, GLDC, HAL, HLCS, IDH1, P4HA1, PRKCE, UGDH, UGP2, UGT2B4, UGT2B7, SLC25A16, VNN2, SLC5A6, KYNU, P4HA2, GLYAT, CRTAP, PRDX4, UGT2A1 |
1870 | GO:0006790 | 0.00 | 1.71 | 81.91 | 110 | 219 | sulfur compound metabolic process | ACACB, ACLY, ACPP, AGXT, AHCY, ANGPT1, BHMT, BTD, CACNA1A, CBS, CDO1, COMT, CPS1, VCAN, CSPG4, CTH, CTNS, DCN, DNMT1, DNMT3B, DPEP1, ESD, EXT1, EXT2, EXTL1, EXTL3, ACSL1, ACSL3, ACSL4, GPC4, GALNS, GAMT, B4GALT1, GGT7, GPC3, GLB1, GOT1, GPX1, GSTM1, GSTM2, GSTZ1, HEXA, HEXB, HLCS, HMGCL, IDH1, IDS, IDUA, IGF1, LIPC, LUM, MAT2A, CHST6, OMD, OGDH, OGN, PDK4, SDC2, SDC4, SLC25A1, SMS, SNCA, SOD1, SP1, STAT5B, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, SUOX, TST, PAX8, PDHX, TPST2, TPST1, DGAT1, B4GALT4, B4GALT3, SUCLG2, SUCLG1, SUCLA2, VNN2, SLC5A6, KYNU, PAPSS2, PAPSS1, B4GALT6, B4GALT5, GSTO1, CHST3, EEF1E1, SDC3, SPOCK2, KEAP1, HS3ST4, HS3ST3B1, ACOT8, GPC6, AASS, CHST4, GLYAT, AKR1A1, B3GNT3, PEMT, AHCYL1, SLC26A1, ACOT2, SLC35D2, KERA |
1871 | GO:0001701 | 0.00 | 1.71 | 69.19 | 93 | 185 | in utero embryonic development | ACVR1, ACVRL1, ADAM10, ADAR, ADD1, ADM, ANGPT1, ARNT, ASCL2, BCL2L1, PRDM1, BMPR1A, BRCA2, BTF3, BYSL, CCNB1, CDX2, CDX4, DAD1, DDX5, DMBT1, EDNRA, EMX1, FUT8, GABPA, GATA4, GATA6, KAT2A, GJB5, GRB2, GRN, HHEX, HIF1A, FOXA2, HES1, IGF1, RBPJ, IHH, IL10, INSL3, ITGA4, ITGB1, KRT19, LLGL2, SMAD3, CITED1, CNOT2, YBX1, P2RY2, PSMC3, PSMC4, PTPRR, RAD51B, RBBP6, RCN1, RXRA, SRSF1, STIL, SNAI1, SOX10, SP1, SPINT1, SRF, ST14, NR2F2, TWIST1, KDM6A, VCAM1, WNT2, XRCC2, FZD5, FOSL1, USP9X, CUL4A, CUL3, COPS3, EIF2S2, SOCS3, LATS1, CCNB2, SLIT2, HAND1, APBA3, CTR9, KEAP1, GINS1, SETDB1, BCL2L11, COL4A3BP, SPEG, KLF2, SLC34A2, TMED2 |
1872 | GO:0034655 | 0.00 | 1.71 | 60.24 | 81 | 162 | nucleobase-containing compound catabolic process | AHCY, ATM, ZFP36L2, CDA, DDX6, DPYD, TYMP, EIF4A1, EIF4E, EIF4G1, ERN1, ETF1, FAU, FEN1, HNRNPD, EIF3E, RPL10A, CNOT2, CNOT4, OAS2, PPP1R8, PPP2R1A, PPP2R2A, UPF1, RNASE2, RNASE6, ABCE1, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, SUPV3L1, ZFP36, CSDE1, PRPF18, KHSRP, RNASET2, RPL14, RQCD1, CNOT8, RPL23, GTPBP1, DHX34, EIF4A3, SMG7, RBM8A, RNASEH2A, ERN2, RNPS1, RPL35 |
1873 | GO:0051051 | 0.02 | 1.70 | 22.98 | 31 | 62 | negative regulation of transport | ARF6, AVPR2, BCR, COMT, CRH, CRHBP, CRY1, ESR1, UTS2R, NRG1, INHA, ITGAV, OXTR, P2RY1, PRKAA1, PRKD1, PTEN, PTGS1, RAC1, SDCBP, STXBP3, SYT4, UCN, NR1H2, FGF23, PICALM, VAMP8, PEA15, UNC119, IL1RAPL1, CORO1A |
1874 | GO:0090150 | 0.01 | 1.70 | 37.89 | 51 | 102 | establishment of protein localization to membrane | ARF6, ASNA1, BAD, BAX, BBS1, BBS2, BCL2, BCL2L1, BID, CAV3, CDH1, EPHA2, ACSL3, FLOT2, GOLGA4, SFN, HSPA4, HSP90AA1, IFNG, ITGA3, ITGB1, KRT18, LAMA5, PPP3R1, MAPK8, RAB13, RDX, CLIP1, S100A10, SLC12A1, TNFRSF1A, TSC2, VIL1, WRB, YWHAZ, UBL4A, BLZF1, DYNLL1, RAB11A, SLC9A3R1, NRXN1, TMEM59, BCL2L11, ARFRP1, RAMP3, SORBS1, VAMP5, RAB10, YWHAQ, RAB31, RER1 |
1875 | GO:0008202 | 0.03 | 1.70 | 21.51 | 29 | 58 | steroid metabolic process | ABCA1, ACADL, ACADVL, AGTR1, APLP2, APP, STS, CAT, COMT, CYP2A6, ESR1, G6PC, FOXA2, LCAT, LIPC, LIPE, STAT5B, SULT1E1, SULT1A1, SULT1A3, SULT2B1, TNFSF4, UGT2B4, UGT2B7, SOAT2, SNX17, DHRS9, DHRS2, DHRS4 |
1876 | GO:0018105 | 0.02 | 1.70 | 25.27 | 34 | 68 | peptidyl-serine phosphorylation | ATM, ATR, BAX, BDKRB2, CAMK4, CAMK2A, CDK2, CLK1, CSNK1D, CSNK1G2, CSNK1G3, DCX, DYRK1A, ERN1, HRC, ILK, SMAD7, PDE4D, PRKCD, PRKCE, PRKCI, PRKCQ, PRKCZ, MAPK8, PRKX, SGK1, VRK2, OGT, MAPKAPK5, RIPK1, EIF2AK3, SGK2, IL24, CHEK2 |
1877 | GO:1903651 | 0.00 | 1.70 | 45.47 | 61 | 122 | positive regulation of cytoplasmic transport | ACTL6A, ARF1, BMP6, BMPR1A, BRCA1, CAMK4, CDH1, CSNK2A2, CTSK, DAB2, EDA, ACSL3, GAS6, KAT2A, SFN, GPR26, HCLS1, NRG1, HNMT, HES1, HSP90AB1, IGF1, IL1B, IL12B, IL18, ITGAX, KPNA1, IPO5, SMAD3, PPM1A, PPP3R1, PRKCD, PRKCQ, RAC2, RDX, RNASE2, SLC9A1, TRIP6, U2AF1, UBE2L3, ZIC1, ZBTB17, FZD5, BAP1, CAMK1, RUVBL1, TNFSF14, HDAC3, CDKL2, SEMA5A, ATG13, FAM20B, SAE1, NUTF2, PEMT, RAPGEF3, ARIH2, CHERP, RBCK1, KHDRBS1, EDAR |
1878 | GO:0022603 | 0.00 | 1.70 | 101.65 | 136 | 276 | regulation of anatomical structure morphogenesis | ANXA1, ANXA7, APOA1, ARHGAP4, BBS4, BMPR2, BNIP3, CACNA1A, CAPZB, CD36, CDX1, CDX2, CHN1, CHRNB2, COL1A1, COL5A2, CSF1R, CYLD, DAPK3, DCC, DIAPH1, DNM2, LPAR1, EFNA5, CTTN, EPHA7, EPHB3, EPS8, F2, FBLN1, FGA, FGD1, FGG, FGR, FYN, GAS2, GDI1, GOLGA4, ARHGAP35, HCK, HEXB, NRG1, FOXA2, ICAM1, IFRD1, IL1RN, ILK, KIT, LIMK1, CAPRIN1, SMAD3, SMAD7, NRCAM, NTRK2, NTRK3, OMG, OPA1, OTX2, PALM, PARK2, PAX3, RELN, PSEN1, PTEN, PTGER4, PTK2, PTPRD, RAC3, RAP2A, RDX, RNF6, RREB1, S100A10, S100A13, S100B, SERPINB3, SDC2, SDCBP, SEMA3F, SFRP5, SGK1, ST6GAL1, SLIT3, SNAI1, SRF, CDKL5, STK11, SYT1, SYT4, CNTN2, TNR, TTC3, VIL1, SEMA3B, RND2, GAS7, RAB11A, NRP1, ARHGEF7, ARHGEF1, ZMYM6, NUMBL, TAOK2, SLIT2, SLC9A3R1, ATG5, AATK, RAPGEF2, RIMS2, IFT140, IST1, CUL7, ARPC2, SEMA3A, CDC42EP2, BAIAP2, MAD2L2, STK25, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, OLFM4, CDC42EP3, PDPN, DMRT2, TNFSF13B, TBR1, SEPT9, FERMT2, CIT, IL1RAPL1, BVES, CORO1A, STRAP |
1879 | GO:0009888 | 0.00 | 1.69 | 98.99 | 133 | 276 | tissue development | ADRB2, AHSG, AMBN, AMELY, ASCL2, BBS2, BGLAP, BMP1, BMP3, BMP8B, BSG, CACNB4, CASQ1, CAV2, RUNX2, SERPINH1, CCNB1, CENPF, COL1A1, COL9A1, COMP, ATF2, CXADR, DCN, DDX5, DHCR24, TSC22D3, ECM1, EEF2, EFNA1, EFNB1, EGR2, ENO3, ERG, EVC, PTK2B, EFEMP1, FGF4, NR5A1, GAA, GAS6, GHSR, GPLD1, HLF, HLX, HMGCR, HMGCS2, HOXD3, HOXD9, HOXD10, IFRD1, ITGAM, KCNK2, KRT6B, LTF, LUM, NRTN, OMD, OGDH, OXCT1, P2RX7, PHEX, PLN, PRRX1, PRKAA1, PRKCQ, PTEN, PTGIS, RB1, REST, RPS6KB1, RYR1, S100A4, S100B, SERPINB3, SDCBP, SEMA3F, SGCB, SLC9A1, SVIL, TAZ, KLF10, CLEC3B, TP73, TUFT1, UBB, ZBTB17, SEMA3B, KCNAB1, CSRP3, FGF23, SORBS2, SERPINB7, ADAM15, SAP30, NRP2, CFLAR, HDAC3, PHOX2B, USP2, DYRK1B, CTDP1, ITGB1BP1, COPS2, GTF3C5, EIF2AK3, AKAP6, ATG5, MINPP1, ZNF516, HDAC4, MAML1, CUL7, NR1D2, LRRC17, SPEG, HMG20B, GPNMB, MAD2L2, CARM1, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, ATG7, VAMP5, ARID5A, USP19, VAX1, BVES, STRAP, ADAMTS7 |
1880 | GO:0043408 | 0.03 | 1.69 | 23.01 | 31 | 63 | regulation of MAPK cascade | AMBP, BMP1, BMP3, BMP6, BMP8B, CRYBA1, EPHA2, EPHA7, EPHB1, FBLN1, GDF9, IGBP1, INHA, PRDX1, PARK2, PER1, PTPRR, RAP2A, STYX, VRK2, HDAC3, ITGB1BP1, KLF4, SLC9A3R1, GDF15, RANBP9, ATP6AP2, RNF41, TNIP1, ZMYND11, COPS5 |
1881 | GO:0006839 | 0.00 | 1.69 | 59.09 | 79 | 158 | mitochondrial transport | ACACB, ACTL6A, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP5O, BAD, BAX, BCL2, BCL2L1, BID, BNIP3, BNIP3L, TSPO, CAMK2A, CDKN2A, CNP, CPT1B, CPT2, ATF2, CSNK2A2, CTSK, EYA2, KAT2A, GFER, SFN, GPR26, NRG1, HNMT, HES1, HSPA4, HSPA9, HSP90AA1, ITGAX, PARK2, PPP3R1, MAPK8, PSEN1, RAC2, RNASE2, SLC1A3, SLC8A3, SLC9A1, SREBF1, STAT3, TST, U2AF1, UBE2L3, UCP1, YWHAZ, ZBTB17, FZD5, BAP1, SLC25A12, RUVBL1, DYNLL1, CDKL2, BAG4, ATP5J2, ATG13, TOMM20, FAM20B, BCL2L11, SAE1, SLC25A13, SLC25A15, PEMT, ARIH2, ACAA2, ATP5H, SIVA1, ATP5L, AFG3L2, TOMM34, YWHAQ |
1882 | GO:0009057 | 0.02 | 1.69 | 26.78 | 36 | 73 | macromolecule catabolic process | ADRA2A, AMBP, BARD1, CAPN1, CBLB, CDC42, TPP1, CLN5, CTSD, CTSE, ACE, FYN, GPLD1, GRIN2A, NRG1, IFNG, IL1B, IL10, SMAD3, OAZ1, OAZ2, P2RX7, PGC, PTPN1, SOX9, TNFRSF1B, TRAF2, UVRAG, VIP, BECN1, ADAM9, TRIM24, SEC22B, GPRASP1, APC2, ATG7 |
1883 | GO:0000122 | 0.00 | 1.69 | 143.99 | 191 | 385 | negative regulation of transcription from RNA polymerase II promoter | ACVR2B, AEBP1, NR0B1, ASCL1, ASCL2, RERE, ATRX, BACH1, CCND1, PRDM1, BMI1, BMP4, BMP6, KLF5, CD36, CDX2, CDX4, CHD4, ATF2, CRY1, CRY2, CRYM, DDIT3, DDX5, DNMT1, DNMT3B, DRD3, TSC22D3, E2F6, E4F1, EFNA1, EN1, EP300, ERF, ETV3, ETV6, FGFR3, FRK, GABPA, GATA6, NR6A1, GFI1, GPS2, ARHGAP35, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HBE1, HCLS1, HDGF, HHEX, HIC1, HIF1A, HMX1, FOXA2, HOXD8, HOXD9, HES1, HSF4, IFI16, IFNG, IGBP1, RBPJ, IL1B, IRF2, ISL1, JARID2, JUN, JUND, LMO1, SMAD3, SMAD7, CIITA, CNOT2, YBX1, ORC2, OVOL1, PARK2, PAWR, PAX3, PAX4, PER1, PRRX1, PPID, PPM1A, PSEN1, RARA, RARB, RB1, RBL1, RELB, REST, RREB1, RXRA, S100A1, SALL1, SATB1, SFPQ, SIM2, SIX1, SMARCA2, SMARCA4, SMARCC2, SNAI1, SNCA, SOX2, SOX3, SOX11, SP100, SREBF1, SRF, SRY, STAT1, STAT3, STAT6, SUPT4H1, SUV39H1, TAF7, TAL1, TBL1X, ZEB1, NR2F1, NR2F2, KLF10, TP73, NR2C1, TWIST1, UBB, SCGB1A1, NR1H2, WFS1, WHSC1, YY1, ZFP36, ZNF8, ZNF136, ZNF148, ZNF157, ZNF174, ZNF177, ZNF189, ZNF217, HMGA2, NRIP1, USP9X, FZD8, GFI1B, SOX14, UXT, CUL3, KLF11, CBX4, TP63, URI1, EED, SAP30, HDAC3, PER3, RNF8, USP2, AURKB, KLF4, COPS2, RECQL5, HAND1, ZNF254, CTR9, ST18, HDAC4, ZEB2, SETDB1, NR1H4, NR2E3, SORBS3, OLIG2, IKZF1, HMG20A, CITED2, MAD2L2, SEMA4D, HEXIM1, TXNIP, CTCF, ZMYND11, ZNF234, VAX1, WWP2, PRDM5, STRAP, DDX20 |
1884 | GO:0051346 | 0.00 | 1.68 | 75.73 | 101 | 203 | negative regulation of hydrolase activity | A2M, ABL1, AHSG, AKT2, AMBP, ANXA1, APCS, BIRC2, BIRC3, XIAP, BIRC5, APLP2, APOA1, APP, AVP, BICD1, BST2, SERPING1, C3, SERPINH1, CD44, COL4A3, COL6A3, CRY2, CSNK2A1, CST6, DHCR24, DLG2, DLG3, DPEP1, ECM1, SERPINB1, GAS6, GPC3, GNAT1, SFN, GPX1, SERPIND1, HGF, HRG, IFI16, IFIT1, IGBP1, ITIH1, ITIH3, ITIH4, KNG1, PEBP1, SERPINE1, SERPINB2, SERPINA5, SERPINF1, PI3, SERPINA4, SERPINB5, SERPINB8, SERPINB9, SERPINB10, SERPINB13, SERPINI2, PRKCZ, PZP, RAF1, RAG1, RENBP, RGS2, RPS6KA1, SORT1, SERPINB3, SERPINB4, SLPI, SNCA, SPINK1, SPINT1, SPOCK1, SERPINA7, TRAF2, VIL1, VTN, PICALM, RECK, SERPINB7, TRADD, URI1, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR, USP14, KLF4, PSMF1, BAG4, PPP1R26, FARP1, CD2BP2, SEMA4D, SPINT3, PRDX3, SPINK5 |
1885 | GO:0006805 | 0.01 | 1.68 | 30.64 | 41 | 82 | xenobiotic metabolic process | ACY1, ADH1B, ADH5, AHCY, ALDH1A1, ALDH2, ALDH3A1, AOC2, COMT, CYP2A6, CYP2A13, CYP2F1, CYP3A4, CYP8B1, CYP11B1, CYP24A1, CYP51A1, DPEP1, ESD, FDXR, GSTZ1, MAT2A, PTGIS, PTGS1, S100A12, STAR, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, TPMT, UGDH, UGP2, UGT2B4, CES2, PAPSS2, PAPSS1, GLYAT, AKR1A1, SLC26A1 |
1886 | GO:0002699 | 0.02 | 1.68 | 27.65 | 37 | 74 | positive regulation of immune effector process | ANXA1, C3, CD28, CD80, CD86, CD36, CD37, FCER2, FFAR3, HLX, HPX, IFNG, IL1B, IL12B, IL13RA2, CD46, P2RX7, PGC, PRKCZ, PVR, RAC2, RARA, RPS19, XCL1, STAT5B, STAT6, STXBP2, TRAF2, TNFSF4, TNFRSF4, UNG, VAV1, WHSC1, FZD5, RIPK2, SPON2, MALT1 |
1887 | GO:0007166 | 0.00 | 1.68 | 155.16 | 208 | 452 | cell surface receptor signaling pathway | ABCA1, ACPP, ADORA3, ANXA1, ARNTL, ATP1A3, BAG1, ADGRB1, ADGRB2, BAX, BCL2, BCL2A1, BCL2L1, BID, BOK, BRCA1, BSG, CACNB3, CACNB4, CALCR, CBLB, CCNE1, CD3D, CD3G, CD9, CD36, CD37, CD38, CD53, CD59, CD79B, CD81, ADGRE5, CD151, CDA, COL1A1, COL4A3, CR2, CRH, CRHBP, CSNK1D, CSNK1G2, CSNK1G3, CSNK2A1, CSNK2A2, CTLA4, CTNND2, DAPK3, DBH, DCC, DDIT3, EDN3, CTTN, EVC, EYA2, F2, FCGRT, GPC4, FGA, FGG, FYB, FZD2, GAS1, GCGR, GLP1R, GNAQ, GPR19, GRK6, GPX1, GRIA1, GRIA4, GRID1, GRIK3, GRM1, GRM8, HIC1, ICAM2, ICAM3, IHH, IL17A, ISL1, CD82, KCNN4, KLRB1, KLRD1, TACSTD2, MAL, MGAT3, SEPT2, OXTR, P2RX1, P2RX3, P2RX5, P2RX7, P2RY1, P2RY2, P2RY4, P2RY6, PAWR, PDE4B, PDE4D, CDK14, PRRX1, PPP2R1B, PPP3R1, PTH2R, RAB5A, RB1, PRPH2, RYK, SAG, SALL1, TSPAN31, SCTR, SEMA3F, SFRP4, SFRP5, STIL, SIX3, SMARCA4, SOX10, SPN, TROVE2, STRN, CNTN2, TSPAN7, TULP3, UBE2D2, UPK1B, KDM6A, VIPR1, VIPR2, TRPV1, LAT2, WNT2, WNT11, WNT2B, ZIC1, FZD5, SCG2, SEMA3B, FZD6, FZD7, FZD8, FZD9, SRPX, DYRK2, RGS20, UNC5C, SSNA1, PTCH2, CRADD, TNFSF10, IL18RAP, CFLAR, WISP1, TRPA1, SEMA5A, LATS1, GPR50, BCL7B, KLF4, GLP2R, GRAP2, THEMIS2, BAG3, SEMA3E, IFT140, KIAA0141, RB1CC1, ZEB2, FARP2, P2RY14, CASP8AP2, ZBTB33, BCL2L10, FRAT1, GPC6, TSPAN2, TSPAN1, FEM1B, G3BP1, ATP6AP2, RNF41, CALCRL, APC2, ABCA7, CACNG2, SEMA3A, MAD2L2, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, SIVA1, KHDRBS1, ZMYND11, PROKR1, GPR83, MALT1, BRD8, IFT27, UPK1A, BTN3A1, CD160, CORO1A, FZD10 |
1888 | GO:0006720 | 0.04 | 1.68 | 20.92 | 28 | 56 | isoprenoid metabolic process | ABCA4, ADH5, ALDH1A1, ALDH3A2, APOA1, OPN1SW, AKR1C4, CLPS, CRH, CYP3A4, GPC4, OPN1MW, GPC3, IL1B, PDE3A, RBP2, OPN1LW, RPE65, SDC2, SDC4, SLC12A1, SRD5A1, STAR, DGAT1, DPM2, DHRS3, SDC3, GPC6 |
1889 | GO:0000723 | 0.03 | 1.68 | 21.67 | 29 | 58 | telomere maintenance | ATM, ATR, ATRX, CCT6A, DKC1, ERCC1, ERCC4, HNRNPC, PRKCQ, RAD51D, UPF1, SP100, CCT3, XRCC5, HIST1H4I, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, MAPKAPK5, AURKB, DCLRE1A, RAD50, CCT7, CCT4, CCT2 |
1890 | GO:0016925 | 0.01 | 1.68 | 32.16 | 43 | 86 | protein sumoylation | BIRC5, ARNT, BMI1, BRCA1, CDKN2A, PHC1, PHC2, EGR2, EYA1, HNRNPC, NUP88, NUP98, PCNA, RAD21, RAD52, RANBP2, RANGAP1, SUMO3, SP100, AURKA, TOP1, TOP2A, TOP2B, SUMO1, XPC, XRCC4, NUP214, AAAS, SMC1A, CBX4, HERC2, SMC3, AURKB, NUP155, NUP93, HDAC4, UBA2, SAE1, HMG20B, PIAS3, STAG2, NUP50, NUPL2 |
1891 | GO:2001252 | 0.01 | 1.68 | 31.42 | 42 | 84 | positive regulation of chromosome organization | ATM, ATR, ATRX, BRCA1, CCNB1, CCT6A, CDK9, DKC1, DNMT1, DNMT3B, ERCC1, GCG, KAT2A, HIST1H1B, IL1B, ISL1, JARID2, PRKD1, PRKCQ, PTEN, RB1, SFPQ, SREBF1, TAL1, CCT3, CUL3, OGT, MAPKAPK5, BECN1, EED, KAT2B, RPS6KA4, AURKB, CTR9, DLGAP5, RNF40, RAD50, CCT7, CCT4, CCT2, RUVBL2, ARID5A |
1892 | GO:0007126 | 0.01 | 1.68 | 29.92 | 40 | 80 | meiotic nuclear division | ADCY3, ATM, BRCA2, BRDT, CDC20, CDK2, CKS2, EREG, ERCC4, FANCA, FANCD2, GOLGA2, GPR3, ING2, PDE3A, PPP2R1A, PRKAR1A, RAD1, RAD21, RAD51, RAD51C, RAD51B, RAD51D, AURKA, TOP2A, TOP2B, UBB, XRCC2, SMC1A, FKBP6, SMC3, ZW10, REC8, SMC4, ACTR2, RAD50, TUBGCP3, STAG3, TUBGCP2, PIM2 |
1893 | GO:0050773 | 0.02 | 1.68 | 24.68 | 33 | 66 | regulation of dendrite development | ARF1, ARF6, CDC20, CHRNB2, DCC, LPAR1, EFNA1, GRN, NRG1, ILK, CAPRIN1, NTRK2, OPA1, PALM, RELN, PSEN1, PTEN, PTPRD, RAP2A, SDC2, SGK1, CDKL5, STK11, CAMK1, NUMBL, RAPGEF2, CUL7, KIAA0319, BAIAP2, CARM1, SEMA4D, CIT, IL1RAPL1 |
1894 | GO:0006821 | 0.03 | 1.68 | 23.19 | 31 | 62 | chloride transport | TSPO, CA2, CFTR, CLCA1, CLCN3, CLCN5, CLCN6, CLCN7, CLCNKA, CLCNKB, CLNS1A, GABRA4, GABRA5, GABRA6, GABRE, GABRG1, GABRR1, GABRR2, GLRA1, GLRA2, P2RY4, P2RY6, FXYD3, PTAFR, SLC4A1, SLC12A1, SLC12A2, SLC12A3, CLCA2, SLC12A6, SLC26A1 |
1895 | GO:0034754 | 0.03 | 1.68 | 21.69 | 29 | 58 | cellular hormone metabolic process | ADM, ALDH1A1, ALDH1A3, BMP6, AKR1C4, COMT, CYP3A4, CYP11B1, ESR1, FDXR, FSHB, IL1B, RBP1, REST, RPE65, SRD5A1, STAR, STAT5B, SULT1E1, SULT1A1, UGT2B4, UGT2B7, HSD17B6, AKR1C3, DGAT1, ALDH1A2, DHRS3, DHRS9, DHRS2 |
1896 | GO:0032479 | 0.04 | 1.68 | 20.20 | 27 | 54 | regulation of type I interferon production | CHUK, CYLD, DHX9, EP300, IFI16, IL10, IRAK1, IRF1, IRF5, PCBP2, PPM1B, RELB, TRIM21, STAT6, TNFAIP3, UBB, UBA7, XRCC5, TRIM25, IKBKG, RIPK1, RIPK2, TAX1BP1, ATG12, ATG5, TRAIP, TRIM38 |
1897 | GO:0034101 | 0.04 | 1.68 | 20.20 | 27 | 54 | erythrocyte homeostasis | ACVR2A, ADAR, ADD1, ALAS2, ARNT, AXL, BMP4, CDK6, DNASE2, ETS1, HCLS1, HIF1A, INHA, KIT, SLC11A2, PRDX1, RB1, RHAG, RPS19, SP1, SRF, STAT5B, TAL1, ZNF16, IKZF1, KLF2, GAS2L1 |
1898 | GO:0044708 | 0.01 | 1.68 | 29.11 | 39 | 79 | single-organism behavior | ABAT, AGTR2, APRT, ARCN1, AVP, BBS2, BBS4, TSPO, CACNA1A, CACNB4, CHRNB4, CLCN3, CNP, DNM1, EPS8, GFI1, GHSR, GLRA1, FOXA2, HOXD9, HOXD10, HPRT1, KCND2, KCNJ10, P2RX3, PRKCE, SCN1A, SCN8A, SLC1A3, SNCA, TBCE, TMOD1, TSC1, TRPV1, ZIC1, DDO, USP2, ATG7, CHL1 |
1899 | GO:0006906 | 0.04 | 1.68 | 19.45 | 26 | 52 | vesicle fusion | AKT2, ANXA1, CAV2, LRMP, SNAP25, STXBP1, SYT1, SYT4, UVRAG, RAB7A, DYSF, EEA1, USO1, VAMP8, STX16, STX11, STX10, SEC22C, SNAP29, GOSR1, SEC22B, C2CD5, VAV3, YKT6, VAMP5, CORO1A |
1900 | GO:0065008 | 0.00 | 1.68 | 146.03 | 196 | 435 | regulation of biological quality | AARS, ARF6, ARHGAP4, ADGRB1, ADGRB2, HCN2, BCR, ZFP36L2, CACNB3, CAPG, CASP1, CD81, CDC20, CDK4, CDKN2A, CHRNB2, CIRBP, CNGA1, CNR2, CREBL2, CTNNA2, CTNND2, CX3CR1, DBI, DCC, DHX9, DNM2, DPP6, EGR2, EIF4G1, ELAVL1, CTTN, EPHA7, EPHB1, EPHB3, ETV5, FLOT2, GAPDH, KAT2A, GLRA1, GOLGA4, GPR26, GRIA1, GRID2, GRIK3, GRIN2A, HIST1H1B, HNRNPD, HRH1, HRH2, HSP90AB1, IFRD1, KCNA2, KCND2, KCND3, KCNJ8, KCNK2, TNPO1, LIMK1, NRCAM, YBX1, NTRK1, OMG, PAWR, PEX6, ATP8B1, RELN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PYY, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTPRJ, PTPRM, PEX19, PYCR1, RARA, RGS2, RNF6, SCN1A, SCN2A, SCN3A, SCN8A, SEL1L, SEMA3F, SET, SIAH1, SIX1, TRIM21, AURKA, CDKL5, SYP, CNTN2, TMOD1, TNFRSF1B, TNNC1, TNNT2, TNR, TPBG, TSC1, SUMO1, SCGB1A1, USP4, ZFP36, ZNF207, SEMA3B, ANP32A, RND2, CNTNAP1, CAMK1, KHSRP, KCNK5, PEX11A, DPM2, NRP1, HDAC3, KAT2B, WASF1, USP13, SEMA5A, USP2, ITGB1BP1, S1PR2, SLC9A3R2, SLIT2, CRIPT, QKI, PICK1, AKAP7, PSMF1, BAG4, BAG3, RIN1, AATK, RAPGEF2, FRMPD4, EIF4A3, PIEZO1, IST1, RB1CC1, PSMD6, USP3, KCNE3, HDAC6, ATP9A, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN1, ARPC2, ABI2, PSME3, PSMD14, ABCA7, CACNG2, ATP8A1, PIAS3, TMEM147, IFI30, CRTAP, SEMA6C, SEMA6B, SEMA4F, SEMA4B, ARL6IP5, ARPC1A, ARFGEF1, AVIL, GIPC1, USP19, PRDX3, PIM2, WWP2, CDC37, CHEK2 |
1901 | GO:0006357 | 0.00 | 1.67 | 49.27 | 66 | 136 | regulation of transcription from RNA polymerase II promoter | ABCA2, ACTL6A, BMP1, BMP8B, KLF9, CHD1, CHD2, CHD3, CHEK1, DGKQ, ECM1, ERG, GDF9, GSC2, HMGN1, HNF4G, MAZ, PAM, PFN1, PRKAR1A, PTAFR, PURA, RBL2, RFX1, RFX2, RYR2, SMARCD1, SMARCD3, SMARCE1, SOD2, SP4, SPIB, STAT2, TAF13, TAL2, ZNF354A, UBE2D2, UCP1, ZIC2, ZNF76, ZNF143, VEZF1, ZNF212, BRD3, USP9Y, CUL2, FOXN1, SMARCA5, IKBKAP, BLZF1, RUVBL1, KLF7, CDK13, CTDP1, SLC33A1, CIAO1, LITAF, RNF14, ZFYVE16, ZNF518A, RBX1, SAP18, DEAF1, BRD8, SOX30, SOX21 |
1902 | GO:0009119 | 0.00 | 1.67 | 68.44 | 91 | 183 | ribonucleoside metabolic process | ACACB, ACPP, ADSL, ADSS, AHCY, AK1, AK2, AK4, ALDOB, ALDOC, AMPD2, APRT, ARNT, ATP1A2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V0A1, ATP5O, BAD, TSPO, CDA, COX4I1, COX8A, COX15, CTNS, CTPS1, DLG2, DLG3, DNMT1, DNMT3B, ENO2, ENO3, GAMT, GAPDH, GPD1, HIF1A, HMGCR, HPRT1, HSPA8, IGF1, IMPDH1, IMPDH2, INS, LDHA, LDHC, MAT2A, OGDH, P2RX7, PDC, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PGM1, PPP2R5D, PRKAA1, PRKAG1, PTGDR, SDHC, SNCA, STAT3, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, TAZ, UPP1, UQCRC1, UQCRC2, UQCRH, OGT, PAPSS2, PAPSS1, ATP5J2, HDAC4, SLC25A13, PEMT, ATP5H, ATP5L, AHCYL1, SLC26A1 |
1903 | GO:0051052 | 0.00 | 1.67 | 55.64 | 74 | 149 | regulation of DNA metabolic process | ANXA3, APAF1, AREG, ATM, ATR, ATRX, BAX, BMP4, BMP6, BRCA1, BRCA2, CCT6A, CD28, CDC42, CDK2, CDK9, CDKN2A, CHEK1, DFFA, DNMT1, ERCC1, EREG, ERCC4, EYA1, EYA3, HNRNPC, IFNG, IGF1, IGF1R, IL10, INS, JUN, KPNA1, KPNA2, KITLG, MGMT, OGG1, PCNA, PPP2R1A, PPP4C, PRKCD, RAC1, RAD51, RAD52, RBBP6, RPA2, RPS3, S100A11, SETMAR, SHC1, STAT6, TOP2A, CCT3, TTF1, TWIST1, TNFSF4, UBE2V2, UCN, UNG, WHSC1, XRCC5, ZNF91, HMGA2, SMC1A, CUL4A, RNF8, SMC3, AIFM1, IL27RA, RAD50, CCT7, RAD51AP1, STAG2, CHEK2 |
1904 | GO:0007346 | 0.02 | 1.67 | 27.70 | 37 | 75 | regulation of mitotic cell cycle | ASCL1, BID, CAV2, CDC25C, CDC42, CDKN2A, CENPE, CYLD, DAPK3, E4F1, ERCC3, CHMP1A, PIM1, PRKCQ, PTPN6, RPA3, SDCBP, SKP1, STK10, ADAM17, DYNLT3, CUL1, CDC14A, CDK13, HDAC3, CDC123, TAOK2, SLK, CUL7, OXSR1, SAE1, RAD50, STK25, PDPN, PIM2, CIT, MAP4K5 |
1905 | GO:0006260 | 0.00 | 1.67 | 48.08 | 64 | 129 | DNA replication | ACHE, ACVRL1, ADRA2A, BRCA1, BRCA2, CCNE1, CDC25A, CDC25C, CDK9, CHEK1, DUT, E4F1, TYMP, FEN1, HMGA1, HNRNPC, TONSL, NUP98, ORC1, ORC2, ORC4, ORC5, PPP2R1A, PRIM2, PTMS, RAD1, PURA, RAD51, RBBP6, RBMS1, UPF1, REV3L, RFC3, RFC4, RFC5, RPA2, RPA3, RRM1, RRM2, S100A11, SET, SETMAR, SSRP1, TOP1, TTF1, CDK2AP1, CHAF1B, SMC1A, SMC3, CCNE2, RECQL5, RECQL4, KIAA0101, GINS1, RAD50, RBM14, RNASEH2A, SPHAR, CERS1, STAG2, DBF4, KAT7, SUPT16H, CHEK2 |
1906 | GO:0051235 | 0.01 | 1.66 | 33.04 | 44 | 89 | maintenance of location | ABCA1, ACACB, ALB, APOA1, ARL2, ATP2A1, BBS4, BCL3, TSPO, C3, CD4, CD36, CRP, CRY1, FBN1, NR5A1, GAA, B4GALNT1, GM2A, HEXB, IL1B, IL10, ITGAV, LTBP1, TONSL, SPAG4, STAT5B, TRIP6, NR1H2, UVRAG, NRIP1, DGAT1, TNFSF14, LATS1, CER1, ABCG1, KEAP1, SUPT7L, TACC3, CREB3, KDELR1, OS9, KDELR2, KDELR3 |
1907 | GO:0034641 | 0.00 | 1.66 | 148.57 | 197 | 431 | cellular nitrogen compound metabolic process | ABAT, ACADM, ACADSB, ACO1, AGXT, ALAD, ALAS1, ALAS2, ALDH9A1, AMT, APOA1, ARG1, ARG2, ASL, ASS1, AUH, BCAT1, BCHE, BCKDHA, BGLAP, BTD, CDK4, CDO1, CHAT, CHKB, CHRNB2, CIRBP, CKM, TPP1, CLN5, COMT, CPD, CPOX, CRAT, CTSH, CTSZ, DAZ1, DBH, DBI, DBT, ACE, DIO2, DIO3, SARDH, EEF1A2, EEF1B2, EEF2, EIF1AX, EIF2S1, EIF2B1, EIF2S3, EIF4EBP1, EIF4G2, EIF5, EIF5A, ELAVL1, F2, F7, F10, ACSL3, GALC, B4GALNT1, GATM, GGT7, GLDC, GLUD1, GLUL, GM2A, GOT1, GOT2, GPLD1, GPT, GRB7, GRIN2A, GSTM1, GSTM2, GSTZ1, HLCS, HMBS, HSPB1, HSP90AA1, HSP90AB1, IDE, IGFBP5, IVD, LCAT, LIPC, LTA4H, CAPRIN1, SLC11A2, OAT, OAZ1, OAZ2, OTC, P2RX1, P2RX4, PAH, PCSK5, PCYT1A, PROC, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMB1, PSMB2, PSMB4, PSMB5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PSPH, PYCR1, ALDH18A1, QDPR, RGS2, RNPEP, RPL36AL, RPN2, RPS6KB1, RPS6KB2, SHMT2, SLC5A5, SLC34A1, SLC25A1, SLC22A5, SMS, SOD1, SRD5A1, SRP9, SRP14, SRP19, SRP68, SSR1, SUOX, TACR3, TAT, TSHB, TUFM, TYR, UROS, TRPV1, EIF4H, SLC25A16, BBOX1, NSMAF, DENR, SLC25A12, EIF4EBP3, ALDH4A1, EIF3G, EIF3J, EIF4G3, BECN1, SUCLA2, GGH, PROZ, CDC123, VNN2, SLC5A6, EIF2B3, EIF2B2, EIF2B5, EIF2S2, EIF1AY, PCSK7, GSTO1, PSMF1, GAL3ST1, EIF5B, PSMD6, ABCB6, COL4A3BP, TRAP1, AASS, ATP6AP2, SLC25A15, PSME3, EIF1, EIF1B, BCKDK, ABCA7, CEPT1, PRG3, SLC25A17, EIF3M, IGF2BP3, CORIN, SEC61B, ADAMTS13, HIBADH |
1908 | GO:0006402 | 0.00 | 1.66 | 50.49 | 67 | 135 | mRNA catabolic process | ATM, ZFP36L2, DDX6, EIF4A1, EIF4E, EIF4G1, ERN1, ETF1, FAU, EIF3E, RPL10A, CNOT2, CNOT4, PPP2R1A, PPP2R2A, UPF1, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, SUPV3L1, ZFP36, CSDE1, PRPF18, KHSRP, RPL14, RQCD1, CNOT8, RPL23, GTPBP1, DHX34, EIF4A3, SMG7, RBM8A, RNPS1, RPL35 |
1909 | GO:0044283 | 0.00 | 1.66 | 64.79 | 86 | 175 | small molecule biosynthetic process | ABAT, ACACB, ACADL, ACADM, ACADVL, ADM, AGXT, AHCY, ALDH1A3, ALDH9A1, ALOX12, ALOX15B, ANXA1, ASL, ASS1, AVP, BCAT1, BHMT, BRCA1, CBR1, CBS, CCBL1, CDO1, AKR1C4, CPS1, VCAN, CSPG4, CTH, CYP8B1, DCN, DHFR, DPYD, FGFR4, FSHB, GAD1, GAMT, GATM, GGT7, GLS, GLUD1, GLUL, GPT, HMGCL, HPGD, IDO1, LDHC, LIPC, FADS3, LTA4H, OAT, OTC, PAH, PDK4, PRKAG1, PSPH, PTGIS, PTGS1, ABCD3, PYCR1, ALDH18A1, RBP1, RNPEP, ACSM3, SHMT1, SHMT2, SLC1A3, STK11, UGDH, UGP2, NR1H2, UROS, ACOX2, BBOX1, ALDH4A1, SUCLA2, ALDH1A2, KYNU, FADS2, QKI, NR1H4, ACOT8, DHRS9, PRG3, FAXDC2, SLC27A5, SLC27A2 |
1910 | GO:0009968 | 0.00 | 1.66 | 109.60 | 145 | 297 | negative regulation of signal transduction | ACVR1, ADAR, NR0B1, AMHR2, APOA1, AVP, BAX, CCND1, PRDM1, BRCA1, CAV2, RUNX2, CBL, CBLB, CD3E, CDC42, AP2S1, CLTA, CRHBP, CRY2, CTH, CTNNA1, CX3CR1, DAB2, ECM1, CTTN, EPS15, EYA1, FGA, FGFR3, FGG, FYN, GAS6, GPC3, GRB2, HGF, NRG1, HHEX, HIC1, ONECUT1, HRG, ICAM1, IGFBP2, IGFBP3, IGFBP5, IGFBP6, IHH, IL1A, IL1RN, ISL1, ITGA1, ITGAV, LTF, SMAD3, SMAD6, SMAD7, CITED1, CNOT2, SERPINE1, PAWR, PF4, PRKACB, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, RAF1, RB1, RFNG, RGS10, RGS16, SALL1, CX3CL1, SFRP4, SIX3, SLIT3, SMARCA4, SOX2, SOX9, SOX10, ADAM17, TULP3, TYRO3, UBB, NR1H2, WNT1, WNT11, PXDN, SCG2, RAB7A, STAM, FZD6, RGS20, PTCH2, CHRD, NUMB, PEA15, RGS11, DLK1, NRP1, CFLAR, ARHGEF7, LATS1, RQCD1, DHRS3, S1PR2, ZFYVE9, ONECUT2, PSMF1, CLOCK, ADAMTSL2, EIF4A3, RB1CC1, PSMD6, RBX1, G3BP1, PSME3, PSMD14, TRIB1, STAM2, FSTL3, TRAIP, APC2, ACAA2, MAD2L2, STRAP |
1911 | GO:0045934 | 0.00 | 1.66 | 277.14 | 361 | 741 | negative regulation of nucleobase-containing compound metabolic process | ACVR2B, ACVRL1, ADRA2A, AEBP1, NR0B1, AKT2, BIRC5, APLP1, ARNTL, ASCL1, ASCL2, ATM, RERE, ATR, ATRX, BACH1, BARD1, CCND1, BCL3, BCL7A, PRDM1, BMI1, BMP4, BMP6, BMPR2, BRCA1, BRCA2, KLF5, TSPO, CAT, RUNX2, RUNX1T1, CCNT1, CD36, CD38, CDA, CDK9, CDKN2A, CDX2, CDX4, CENPF, CHD4, CREB1, ATF2, CRY1, CRY2, CRYM, CYLD, DAB2, DDIT3, DDX5, DFFA, DNMT1, DNMT3B, DRD3, TSC22D3, DUSP1, DYRK1A, E2F6, E4F1, LPAR1, EDNRA, EFNA1, EN1, EP300, ERCC1, EREG, ERCC4, ERF, ESR1, ETV3, ETV6, FGFR3, FRK, GABPA, GALR1, GAS6, GATA6, NR6A1, GFI1, GPS2, ARHGAP35, GRM8, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, H2AFZ, HBE1, HCLS1, HDGF, NRG1, HHEX, HIC1, HIF1A, HMGA1, HMX1, FOXA2, HNRNPC, HOXD8, HOXD9, PRMT2, HES1, HSF4, HSPA8, IFI16, IFNA2, IFNG, IGBP1, IGF1R, RBPJ, IL1B, ILF3, IRAK1, IRAK2, IRF1, IRF2, ISL1, JARID2, JUN, JUND, KCNK2, LMO1, SMAD3, SMAD7, CIITA, CITED1, TONSL, CNOT2, YBX1, OGG1, ORC2, OVOL1, PA2G4, PALM, PARK2, PAWR, PAX3, PAX4, PAX9, PBX1, CHMP1A, PER1, PEX14, ATP8B1, PHF2, PIM1, PRRX1, PPID, PPM1A, PSEN1, PSMC3, PTGIS, PTHLH, PURA, RARA, RARB, RB1, RBL1, RELB, REST, RFX3, RPS3, RREB1, RXRA, S100A1, S100A11, SALL1, SATB1, XCL1, SET, SFPQ, SFRP4, SFRP5, SRSF4, SRSF6, SRSF7, SFSWAP, SIM2, SIX1, SIX3, SMARCA2, SMARCA4, SMARCC2, SMARCE1, SNAI1, SNCA, SOX2, SOX3, SOX9, SOX10, SOX11, SP100, SREBF1, SRF, SRY, TRIM21, STAT1, STAT3, STAT6, SUPT4H1, SUV39H1, TAF7, TAL1, TBL1X, TBP, ZEB1, NR2F1, NR2F2, KLF10, TNFAIP3, TP73, NR2C1, TSG101, TTF1, TWIST1, TNFSF4, TNFRSF4, UBB, SUMO1, UBTF, SCGB1A1, NR1H2, WFS1, WHSC1, WNT11, XRCC5, YY1, ZFP36, ZIC2, ZNF8, ZNF24, ZNF91, ZNF136, ZNF148, ZNF154, ZNF157, ZNF174, ZNF177, ZNF189, ZNF217, ZNF224, HMGA2, NRIP1, USP9X, KDM5C, SMC1A, HIST1H4I, FZD6, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, CUL3, KLF11, HAT1, CBX4, TP63, SRSF9, URI1, EED, TRIM24, SAP30, HESX1, HDAC3, PER3, TAX1BP1, HIST1H3F, HIST1H2AG, TAF1C, TAF1B, TAF1A, RNF8, UBA3, USP2, RGN, SMC3, CBFA2T2, AURKB, KLF4, COPS2, RECQL5, HAND1, AKAP6, ZNF254, GABBR2, CLOCK, CTR9, KDM4A, DHX34, ST18, HDAC4, BCLAF1, RNF40, KEAP1, ZEB2, SETDB1, NR1I3, NR1H4, NR1D2, CASP8AP2, NR2E3, ZBTB33, HDAC6, RAD50, ZNF263, ZNF256, SORBS3, TRIM13, OLIG2, TRIB1, RAMP3, SAP18, IKZF1, TRIM22, HMG20A, CITED2, IFITM3, MAD2L2, SEMA4D, DEAF1, SIVA1, ERN2, HEXIM1, RBCK1, TXNIP, KHDRBS1, CTCF, CERS1, STAG2, ZMYND11, ZNF234, ARID5A, RNPS1, YWHAQ, CCDC85B, VAX1, WWP1, WWP2, PRDM5, STRAP, CHEK2, DDX20 |
1912 | GO:1902679 | 0.00 | 1.65 | 236.89 | 309 | 634 | negative regulation of RNA biosynthetic process | ACVR2B, AEBP1, NR0B1, BIRC5, ARNTL, ASCL1, ASCL2, RERE, ATRX, BACH1, CCND1, BCL3, BCL7A, PRDM1, BMI1, BMP4, BMP6, BRCA1, KLF5, CAT, RUNX2, RUNX1T1, CD36, CD38, CDKN2A, CDX2, CDX4, CENPF, CHD4, CREB1, ATF2, CRY1, CRY2, CRYM, CYLD, DAB2, DDIT3, DDX5, DNMT1, DNMT3B, DRD3, TSC22D3, E2F6, E4F1, EFNA1, EN1, EP300, EREG, ERF, ESR1, ETV3, ETV6, FGFR3, FRK, GABPA, GAS6, GATA6, NR6A1, GFI1, GPS2, ARHGAP35, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, H2AFZ, HBE1, HCLS1, HDGF, NRG1, HHEX, HIC1, HIF1A, HMGA1, HMX1, FOXA2, HOXD8, HOXD9, PRMT2, HES1, HSF4, HSPA8, IFI16, IFNA2, IFNG, IGBP1, IGF1R, RBPJ, IL1B, ILF3, IRAK1, IRAK2, IRF1, IRF2, ISL1, JARID2, JUND, LMO1, SMAD3, SMAD7, CIITA, CITED1, TONSL, CNOT2, YBX1, ORC2, OVOL1, PA2G4, PARK2, PAWR, PAX3, PAX4, PAX9, PBX1, CHMP1A, PER1, PEX14, ATP8B1, PHF2, PIM1, PRRX1, PPID, PPM1A, PSEN1, PSMC3, PTGIS, PTHLH, PURA, RARA, RARB, RB1, RBL1, RELB, RFX3, RREB1, RXRA, S100A1, SALL1, SATB1, XCL1, SET, SFPQ, SFRP4, SFRP5, SIM2, SIX1, SIX3, SMARCA2, SMARCA4, SMARCC2, SMARCE1, SNAI1, SNCA, SOX2, SOX3, SOX9, SOX10, SOX11, SREBF1, SRF, SRY, STAT1, STAT3, STAT6, SUPT4H1, SUV39H1, TAF7, TAL1, TBL1X, TBP, ZEB1, NR2F1, NR2F2, KLF10, TNFAIP3, TP73, NR2C1, TSG101, TWIST1, TNFSF4, TNFRSF4, UBB, SUMO1, UBTF, SCGB1A1, NR1H2, WFS1, WHSC1, WNT11, XRCC5, YY1, ZFP36, ZIC2, ZNF8, ZNF24, ZNF91, ZNF136, ZNF148, ZNF154, ZNF157, ZNF174, ZNF177, ZNF189, ZNF217, ZNF224, NRIP1, USP9X, KDM5C, HIST1H4I, FZD6, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, CUL3, KLF11, HAT1, CBX4, TP63, URI1, EED, TRIM24, SAP30, HESX1, HDAC3, PER3, TAX1BP1, HIST1H3F, HIST1H2AG, TAF1C, TAF1B, TAF1A, RNF8, UBA3, USP2, RGN, CBFA2T2, AURKB, KLF4, COPS2, RECQL5, HAND1, ZNF254, CLOCK, CTR9, KDM4A, ST18, HDAC4, BCLAF1, KEAP1, ZEB2, SETDB1, NR1I3, NR1H4, NR1D2, CASP8AP2, NR2E3, ZBTB33, HDAC6, ZNF263, ZNF256, SORBS3, OLIG2, TRIB1, RAMP3, SAP18, IKZF1, TRIM22, HMG20A, CITED2, MAD2L2, SEMA4D, DEAF1, SIVA1, ERN2, HEXIM1, RBCK1, TXNIP, KHDRBS1, CTCF, ZMYND11, ZNF234, ARID5A, YWHAQ, CCDC85B, VAX1, WWP1, WWP2, PRDM5, STRAP, DDX20 |
1913 | GO:0048666 | 0.00 | 1.65 | 69.26 | 92 | 191 | neuron development | ADCY6, ADM, ALK, APOA1, AREG, ARF1, ARF6, ASCL1, BMP4, TSPO, CALU, CDC20, CDH1, CLU, CNR1, CNTF, CTF1, CTNNA1, DHFR, LPAR1, EMX1, EN1, ACSL4, PTK2B, EFEMP1, FZD2, GABRA5, GAK, BLOC1S1, GFAP, GFI1, GPM6A, RAPGEF1, GRID2, GRN, HGF, IHH, ITGA3, JUN, SEPT2, NTF4, OGDH, OPCML, P2RY2, PALM, PARK2, PCP4, SERPINF1, ATP8B1, PRRX1, PRKD1, PRKCZ, PTN, RAB13, RXRA, SDC4, SNAP25, SOX1, SOX3, SPOCK1, AURKA, STRN, SYT1, SYT4, DYNLT1, TP73, UCN, VIM, WEE1, WNT1, GAS7, CAMK1, BECN1, KAT2B, CPNE1, CBFA2T2, KLF4, NREP, CHST3, SLC4A7, ADAMTS1, BAG5, RIMS2, KIAA0319, FIG4, TSPAN2, KATNB1, CARM1, ARFGEF1, AVIL, RAB35, STMN2 |
1914 | GO:0044242 | 0.01 | 1.65 | 38.52 | 51 | 103 | cellular lipid catabolic process | ACAA1, ACACB, ACADL, ACADM, ACADS, ACADSB, ACADVL, ADRB2, AKT2, ABCD1, APOA1, APOH, DAGLA, CNR1, CPS1, CPT1B, CPT2, CRAT, DECR1, ECH1, FAAH, FABP2, FABP6, FABP7, GALC, GM2A, GPLD1, HEXB, IDH1, IVD, LIPC, LIPE, ENPP2, PEX7, PEX13, PRKACB, PRKACG, PRKCD, ABCD3, TWIST1, RAB7A, ACOX2, ACOX3, AKR1C3, LIPG, PRDX6, ACOT8, ECI2, SLC25A17, SLC27A4, SLC27A2 |
1915 | GO:0008064 | 0.01 | 1.65 | 34.78 | 46 | 93 | regulation of actin polymerization or depolymerization | ADD1, ARF1, ARF6, BBS4, CAPG, CAPZA1, CAPZB, CFL2, CTTN, EPS8, F2RL1, PTK2B, GRB2, HCK, HCLS1, ICAM1, PFN1, PFN2, PRKCD, PRKCE, RAC1, RDX, CCL21, CCL24, TMOD1, VIL1, WASF1, SEMA5A, LATS1, SLIT2, PICK1, BAG4, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, ABI2, CDC42EP2, BAIAP2, ARPC1A, ARFGEF1, CDC42EP3, AVIL, CORO1A |
1916 | GO:0010648 | 0.03 | 1.64 | 24.08 | 32 | 66 | negative regulation of cell communication | ACHE, ANXA5, ARF1, BCHE, TSPO, CD38, CNR2, CRH, DRD5, PTK2B, GHSR, GLRA1, GNAI1, GRIA1, GRIK3, INHA, KCNJ11, PDE4C, PTGS1, REST, SLC18A1, SREBF1, SRF, STXBP1, ABCC8, TNR, UCN, FGF23, DGKI, PICK1, STXBP5L, FEZ2 |
1917 | GO:0010506 | 0.02 | 1.64 | 27.21 | 36 | 73 | regulation of autophagy | ABL1, ABL2, ACTL6A, ATM, ATP6V0A1, BCL2, BCL2L1, TSPO, CASP1, CSNK2A2, CTSK, DAPK3, CTTN, ERN1, GATA4, KAT2A, GOLGA2, HGF, IFI16, KIF25, PARK2, SREBF1, TSC1, U2AF1, ZBTB17, FZD5, RAB7A, RUVBL1, USP13, RAB33A, FEZ2, KDM4A, RB1CC1, HDAC6, RRAGA, WDR6 |
1918 | GO:0009152 | 0.05 | 1.64 | 19.63 | 26 | 53 | purine ribonucleotide biosynthetic process | ACACB, ADSS, AK1, AK2, AK4, APRT, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, ATP5O, IMPDH1, IMPDH2, LDHC, STAT3, PAPSS2, PAPSS1, ATP5J2, SLC25A13, ATP5H, ATP5L, SLC26A1 |
1919 | GO:0042742 | 0.03 | 1.64 | 24.96 | 33 | 67 | defense response to bacterium | ANXA3, BCL3, TNFSF8, CD36, CEBPE, CRP, CYBA, FCER1G, FGR, HP, IFNG, RBPJ, IL10, P2RX7, CFP, PRG2, PRKCD, RAB1A, S100A8, S100A9, S100A12, CCL20, CXCL6, SFTPD, SPN, ADAM17, TMF1, TNFRSF1A, RIPK2, IL27RA, ADAMTS4, CXCL13, ADAMTS5 |
1920 | GO:0051494 | 0.02 | 1.64 | 29.55 | 39 | 79 | negative regulation of cytoskeleton organization | ADD1, ARHGAP6, BBS4, BRCA1, CAPG, CAPZA1, CAPZB, CAV3, CCNB1, CCNF, S1PR1, EPS8, TACSTD2, NUBP1, PARK2, PFN1, PFN2, PRKCD, RDX, SGK1, SNCA, AURKA, TBCD, TMOD1, VIL1, ARHGEF2, AURKB, SLIT2, PICK1, HDAC6, WASF2, APC2, KATNB1, RBM14, ARFGEF1, GAS2L1, AVIL, STMN2, CORO1A |
1921 | GO:0044802 | 0.00 | 1.64 | 181.66 | 237 | 487 | single-organism membrane organization | ABCA1, ABCA4, ADRB2, AKT2, ANXA1, ARF6, ASNA1, ATP1B3, BAD, BAX, BBS1, BBS2, BCL2, BCL2A1, BCL2L1, BID, BNIP3, BNIP3L, BSG, CACNA1A, CALCR, CAMK2A, CAV2, CAV3, CCNB1, CD9, CDH1, CLU, CNP, ATF2, DAB2, DLG2, DLG3, DNM2, DPP6, EPHA2, EMP2, STOM, ERBB2, ETV5, EYA2, ACSL3, FAU, FCER1G, FLOT2, FYB, GAS6, GDI1, GOLGA4, SFN, HSPA4, HSP90AA1, IFNG, ITGA3, ITGA4, ITGB1, KCNE1, KCNN4, KRT18, LAMA5, LRMP, MAL, RPL10A, NRCAM, NUP88, NUP98, OPA1, P2RX7, P2RY1, PALM, PARK2, SERPINA5, ATP8B1, PIGR, PPP2R1A, PPP2R2A, PPP3R1, PRKCD, PRKCZ, MAPK8, RELN, PTEN, PTN, PTPRD, PEX19, PEX5, RAB13, RAC1, RANBP2, RAP2A, RDX, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, CLIP1, S100A9, S100A10, SDCBP, SLC9A1, SLC12A1, SNAP25, SNCA, SOD1, SPAG4, SPAM1, SRP9, SRP14, SRP19, SRP68, SSR1, STAT3, STXBP1, SYP, SYT1, SYT4, CNTN2, TAZ, TNFRSF1A, TSC2, TSG101, TUB, TULP1, TULP2, TULP3, SUMO1, UVRAG, VIL1, VRK1, WRB, YWHAZ, RAB7A, NUP214, AAAS, MADCAM1, UBL4A, DYSF, EEA1, TPST2, OGT, BLZF1, SSNA1, NUMB, DYNLL1, VAMP8, STX16, STX11, STX10, RAB11A, BANF1, LIN7A, SYNJ1, AP3D1, RPL14, SYT7, SEC22C, CCNB2, ITGB1BP1, SNAP29, TAOK2, RPL23, SLC9A3R1, NRXN1, NRXN2, PEX16, CRIPT, PICK1, GOSR1, TMEM59, BAG4, NUP155, NUP93, RAPGEF2, TOMM20, C2CD5, BCL2L11, ATP9A, ARFRP1, RAMP2, RAMP3, ZMPSTE24, TRDN, ABCA7, ACAA2, VAV3, BAIAP2, ATG7, SIVA1, SORBS1, YKT6, NUP50, VAMP5, RAB10, AFG3L2, SEC61B, YWHAQ, FERMT2, IMMT, RAB31, RER1, NUPL2, IL1RAPL1, CORO1A, RPL35, SEC63 |
1922 | GO:0034976 | 0.01 | 1.64 | 43.25 | 57 | 116 | response to endoplasmic reticulum stress | AARS, ACADVL, ADD1, ASNA1, CCND1, TPP1, CTH, EEF2, EIF2S1, EP300, EXTL3, HDGF, DNAJB2, IFNG, JUN, DNAJB9, ATXN3, PPP2CB, EIF2AK2, PSMC1, PSMC2, PSMC3, PSMC4, SDF2, SEL1L, SGTA, SHC1, SSR1, SULT1A3, HSP90B1, TRIM25, ZBTB17, RNF103, SRPX, EIF2B5, USP13, USP14, ATP6V0D1, VAPB, GOSR2, TATDN2, CUL7, COL4A3BP, PREB, PDIA6, TRIM13, MARCH6, ERN2, ERLIN1, USP19, SEC61B, PDIA5, OS9, COPS5, KDELR3, ERLIN2, SEC63 |
1923 | GO:0031396 | 0.05 | 1.63 | 20.45 | 27 | 55 | regulation of protein ubiquitination | ABL1, ATM, BUB1B, TSPO, CDK2, CENPF, CRY1, DUSP1, FYN, HSP90AA1, HSP90AB1, LIMK1, PRKCE, RPS3, TNFAIP3, TTK, USP4, ZNF207, OGT, ZW10, ATG5, BAG5, FEM1B, ZER1, MAD2L2, ATG7, GLMN |
1924 | GO:0018393 | 0.03 | 1.63 | 25.81 | 34 | 69 | internal peptidyl-lysine acetylation | ACTL6A, BRCA1, BRCA2, CHEK1, ATF2, EP300, KAT2A, IL1B, ISL1, PER1, SET, SNCA, TAF5, TAF7, TAF10, TWIST1, BRPF1, OGT, HAT1, RUVBL1, KAT2B, RPS6KA4, GTF3C4, ATG5, CLOCK, SUPT7L, ATG7, TRIM16, CTCF, RUVBL2, ARID5A, BRD8, WDR5, KAT7 |
1925 | GO:0009165 | 0.02 | 1.63 | 32.63 | 43 | 88 | nucleotide biosynthetic process | ACACB, ADSL, ADSS, AK1, AK2, AK4, AMPD1, APRT, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, ATP5O, CTPS1, DHFR, DTYMK, DUT, HPRT1, IMPDH1, IMPDH2, LDHC, OAS2, PFAS, PRPSAP1, RRM1, RRM2, SHMT1, STAT3, TYMS, UPP1, KYNU, PAPSS2, PAPSS1, TBPL1, ATP5J2, SLC25A13, ATP5H, ATP5L, SLC26A1 |
1926 | GO:0048562 | 0.01 | 1.63 | 41.05 | 54 | 110 | embryonic organ morphogenesis | ACVR1, ALDH1A3, ATOH1, ATP2B2, ATP6V1B1, BBS4, BCR, DLX5, DLX6, EFNA1, EPHA2, EPHB2, FBN1, EFEMP1, FGF3, FZD2, GATA4, GFI1, HIF1A, HLX, HMX2, HES1, IHH, INSIG1, OTX1, OTX2, PSEN1, RAC1, RARB, RPL38, RYR2, SALL1, STIL, SIX3, SOD1, SOX2, SOX9, SP1, SRF, CLRN1, KDM6A, WNT1, WNT11, ZIC1, PAX8, FZD5, FZD6, ITGA8, HESX1, NRP1, SLC9A3R1, HAND1, SEC24B, GJB6 |
1927 | GO:0001841 | 0.04 | 1.63 | 23.56 | 31 | 63 | neural tube formation | ADM, APAF1, BBS4, BMP4, FZD2, KAT2A, ARHGAP35, HIF1A, OPA1, PAX3, PFN1, PRKACB, RALA, RARA, SALL1, SDC4, STIL, SOX11, SPINT1, ST14, TSC1, TSC2, TULP3, TWIST1, KDM6A, ZIC2, FZD6, ZEB2, SEC24B, DEAF1, GLMN |
1928 | GO:0055114 | 0.00 | 1.62 | 198.83 | 258 | 533 | oxidation-reduction process | ACLY, ACO1, ACO2, ADCY3, ADCY5, ADCY6, ADCY9, ADH1B, ADH5, ADRA1B, ADRA2A, ADSL, ALDH1A1, ALDH2, ALDH3A1, ALDH1A3, ALDH9A1, ALDH3A2, ALDOB, ALDOC, ALOX15B, AOC2, AOX1, APOA1, ARL2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP5O, BAX, BCKDHA, BLVRA, BLVRB, BNIP3, CACNA1A, CALM1, CALM3, CAT, CBR1, CBS, CDO1, AKR1C4, CHRM3, COX4I1, COX5B, COX6A1, COX6B1, COX7C, COX8A, COX15, CPOX, CPS1, CRYM, CRYZ, CYB5A, CYBA, CYBB, CYC1, CYP2A6, CYP2A13, CYP2F1, CYP3A4, CYP8B1, CYP11B1, CYP24A1, CYP51A1, DBH, DHCR7, DHCR24, DHFR, CYB5R3, DIO2, DIO3, SARDH, DPYD, ENO2, ENO3, FDFT1, FDXR, G6PC, GAA, GAPDH, GCG, GCGR, BLOC1S1, GDI1, GDI2, GFER, GLDC, GLP1R, GLUD1, GNAS, GNB1, GNG3, GNG10, GNG11, GPD1, GPD2, FFAR1, GPX1, GPX2, GPX3, GPX7, GYS2, HSD17B10, HCCS, HIF1A, HMGCR, HPGD, HSD11B1, IDH1, IDH3A, IGF1, IGF2, IMPDH1, IMPDH2, IDO1, INS, ITPR1, ITPR2, KCNC2, KCNJ11, KCNS3, KHK, LDHA, LDHC, FADS3, MDH1, MDH2, ALDH6A1, OGDH, P4HA1, PRDX1, PAH, PAM, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PGM1, PHF2, PHKA1, PHKA2, PHKB, PHKG1, PPP1R1A, PPP1R2, PPP2R5D, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PTGIS, PTGS1, PYCR1, ALDH18A1, PYGB, PYGL, PYGM, QDPR, RRM1, RRM2, SDHA, SDHB, SDHC, SDHD, SLC1A3, SLC2A1, SNAP25, SNCA, SOD1, SOD2, SORD, SRD5A1, STK11, STXBP1, SUOX, ABCC8, SYT5, TAZ, TST, TYR, TYRP1, UBB, UCN, UCP1, UGDH, UGP2, UQCRC1, UQCRC2, UQCRH, KDM6A, UTY, VCAM1, PXDN, KCNAB1, EPM2A, COIL, KDM5C, EPX, BBOX1, DYRK2, DDO, AGPS, PIR, SLC25A12, HSD17B6, AKR1C3, ALDH4A1, SUCLG2, SUCLG1, SUCLA2, ALKBH1, ALDH1A2, P4HA2, CH25H, AIFM1, COX7A2L, DHRS3, FADS2, GSTO1, TP53I3, ATP5J2, PRDX6, KDM4A, HEPH, EPM2AIP1, TRAP1, AASS, SLC25A13, DHRS9, DHRS2, ABCC4, AKR1A1, RAPGEF3, IFI30, ATP5H, ENOX2, PRDX4, SORBS1, ATP5L, FAXDC2, ALDH1L1, DHRS4, PRDX3, PDIA5, UQCR11, DUS4L, CYB561D2, RAPGEF4, HIBADH |
1929 | GO:1903829 | 0.00 | 1.62 | 48.74 | 64 | 131 | positive regulation of cellular protein localization | ACTL6A, AKT2, ARF6, BAD, BCL2, BID, CAMK4, CCNB1, CDC42, CHRM1, CSNK2A2, CTSK, DKC1, EPHA2, STOM, ERBB2, ACSL3, GAS6, KAT2A, SFN, GPR26, NRG1, HNMT, HES1, IFNG, ITGA3, ITGAX, ITGB1, OAZ1, OAZ2, PCM1, PPM1A, PRKCI, MAPK8, PTN, RAC2, RDX, RNASE2, U2AF1, UBE2L3, VIL1, YWHAZ, ZBTB17, FZD5, BAP1, CAMK1, RUVBL1, DYNLL1, BECN1, CDKL2, ITGB1BP1, NRXN1, ATG13, C2CD5, FAM20B, BCL2L11, SAE1, RAMP3, PEMT, RAPGEF3, ARIH2, SORBS1, YWHAQ, RER1 |
1930 | GO:0060627 | 0.01 | 1.62 | 44.93 | 59 | 121 | regulation of vesicle-mediated transport | ADRA2A, AKT2, ANXA1, ATP6AP1, CACNA1A, CFTR, DNM1, ACSL3, FGA, FGG, GAS1, B4GALT1, GLRA1, IFNG, IL13, IL13RA2, INSIG1, PARK2, PFN2, SEPT5, PRKAA1, PTAFR, RAB3B, RAB27B, RAC2, RALA, RDX, REST, SDC4, SPINK1, STXBP1, STXBP2, STXBP3, SYN1, SYT1, SYT4, UVRAG, RAB7A, STAM, DOC2A, VAMP8, RAB11A, NRP1, SYT7, RAB9A, STXBP5L, GOSR1, RAB3D, RIMS2, GAB2, C2CD5, PDCD6IP, SEC24B, CPLX2, CPLX1, RAPGEF4, IL1RAPL1, BVES, CORO1A |
1931 | GO:0043244 | 0.05 | 1.62 | 21.32 | 28 | 57 | regulation of protein complex disassembly | ADD1, BNIP3, CAPG, CAPZA1, CAPZB, CCNB1, CFL2, EIF5A, EPS8, ETF1, F2RL1, RDX, UPF1, SLN, SPAST, AURKA, TMOD1, VIL1, SYNJ1, SEMA5A, ARHGEF2, AURKB, HDAC6, APC2, KATNB1, GAS2L1, AVIL, STMN2 |
1932 | GO:0051304 | 0.05 | 1.62 | 21.32 | 28 | 57 | chromosome separation | ATM, BUB1B, CCNB1, CDC20, CDC27, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, ERCC4, PPP2R1A, PTEN, RB1, TOP2A, TOP2B, TTK, ZNF207, CUL3, CDC23, CDC16, ZW10, RECQL5, DLGAP5, ANAPC10, MAD2L2, UBE2C, CIT |
1933 | GO:0000902 | 0.00 | 1.62 | 319.40 | 410 | 854 | cell morphogenesis | ABL1, ABL2, ACTB, ACTG1, ACTN1, ADAM10, ADD1, ANGPT1, ANXA1, ANXA7, APOA1, APP, ARAF, ARHGAP4, RERE, ATOH1, ATP2B2, AXL, ADGRB1, BBS1, BBS2, BBS4, BCL2, BMP4, BMPR2, CACNA1A, CACNB3, CACNB4, CALM1, CALM3, CAMK2A, CAPZB, CASP9, CCK, CD72, CDC42, CHN1, CHRNB2, AP2S1, CLU, CLTA, CNP, COL1A1, COL3A1, COL4A3, COL4A5, COL5A2, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CLDN3, CREB1, CRYGB, CSF1R, CSF2RB, CSNK1D, CSNK2A1, CSNK2A2, CTNNA2, CTNND2, CYLD, DAB2, DAPK3, DCC, DCX, DIAPH1, DLG3, DLX5, DNM1, DNAH5, DNM2, DPYSL3, EPYC, HBEGF, ECM2, DUSP5, E2F4, LPAR1, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EPHA2, EMX1, CTTN, EP300, EPHA1, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPS8, ERBB2, EREG, ERG, ETV4, EXT1, F2, PTK2B, FBLN1, FGA, FGD1, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FGG, FGR, FYN, GAS2, GDI1, GFRA1, GOLGA4, GP1BA, GPM6A, GRB2, GRIN2A, ARHGAP35, HCK, HEXB, HGF, NRG1, HIF1A, FOXA2, ONECUT1, HPRT1, HRH2, HES1, HSPA8, HSP90AA1, HSP90AB1, ICAM1, IDUA, IFRD1, RBPJ, IHH, IL2RA, ILK, ISL1, ITGA1, ITGA4, ITGA5, ITGA9, ITGAV, ITGB1, KDR, KIF5A, KIT, KRAS, LAMA5, ABLIM1, LIMK1, TACSTD2, CAPRIN1, SMAD3, SMAD7, MAP6, MARK3, KITLG, CITED1, SEPT2, SLC11A2, NRCAM, NRTN, NTF3, NTF4, NTRK1, NTRK2, NTRK3, NTN3, OGN, OMG, OTX2, P2RX7, PEBP1, PALM, PARK2, PCM1, ENPP2, PPP5C, PRKCQ, PRKCZ, PSPN, RELN, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, PTN, PTPN6, PTPRA, PTPRD, PTPRM, RAB1A, RAC1, RAC2, RAC3, RAF1, RAP2A, RASA2, RB1, RDX, RFX3, RNF6, RPGR, RPL24, RPS6KA1, RREB1, RYK, S100A4, S100A6, S100A10, S100A13, S100B, SALL1, SERPINB3, SCN5A, CCL24, SDC2, SDCBP, SEMA3F, SGK1, SHC1, SIAH1, ST6GAL1, STIL, SLC1A3, SLIT3, SNAI1, SOD1, SOS1, SOS2, SOX9, SPAG1, SPARC, SPAST, SRF, TROVE2, ST14, STAT1, STC1, AURKA, CDKL5, STK11, STXBP1, SYT1, SYT4, TAL1, CNTN2, TBCE, DYNLT1, TNR, TOP2B, TRPC1, TRPC3, TRPC4, TRPC5, TTC3, TWIST1, TYRO3, TYROBP, UBB, UPK3A, CLRN1, VIL1, WEE1, WNT2, WNT11, PAX8, SEMA3B, FGF23, HMGA2, RND2, USP9X, PICALM, FZD4, FZD7, CUL3, CNTNAP1, ITGA8, GAS7, CDC14A, KLF7, UNC5C, NUMB, DYNLL1, PEA15, ADAM15, RAB11A, NRP2, NRP1, ARHGEF7, CPNE1, PHOX2B, WASF1, RPS6KA4, KALRN, SEMA5A, LATS1, ATP6V0D1, ARHGEF1, ARHGEF2, ZMYM6, NUMBL, ITGB1BP1, SNAP29, TAOK2, SLIT2, SLC9A3R1, NRXN3, NRXN1, ATG5, ONECUT2, PSMF1, NRG2, AATK, FEZ2, RAPGEF2, RIMS2, SEMA3E, IFT140, IST1, CUL7, ARHGEF11, FARP2, PSMD6, RBX1, ABI1, RANBP9, COL4A3BP, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, FARP1, WASF2, PSME3, PSMD14, ABCC4, KLF2, SEMA3A, SPON2, SEC24B, CDC42EP2, VAV3, BAIAP2, MAD2L2, SLC9A6, CAP1, STK25, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, ATG7, ARPC1A, OLFM4, DPYSL4, CDC42EP3, PDPN, AVIL, TBR1, CHL1, SEPT9, FRS3, RAB10, AFG3L2, FERMT2, VAX1, CIT, KIF3A, IL1RAPL1, BVES, CORO1A, STRAP |
1934 | GO:0007219 | 0.01 | 1.62 | 35.86 | 47 | 96 | Notch signaling pathway | ADAM10, AGXT, APP, ATOH1, CCND1, CCNC, CDH6, CDK6, CDK8, CREB1, S1PR3, EP300, FCER2, B4GALT1, GMDS, GOT1, HHEX, HIF1A, FOXA2, ONECUT1, HOXD3, RBPJ, IL2RA, KRT19, LLGL2, CD46, PGAM2, PLN, PSEN1, RPS19, SEL1L, SKP1, SNAI1, SOX9, ADAM17, TBL1X, UBB, CUL1, SORBS2, NUMB, DLK1, HDAC3, KAT2B, MAML1, NR1H4, RBX1, RCAN2 |
1935 | GO:0006605 | 0.00 | 1.61 | 50.47 | 66 | 137 | protein targeting | ADAR, ARNTL, RERE, BID, TSPO, CBLB, SCARB2, CSE1L, F2R, FYB, GFER, GOLGA4, HSPA4, HSPA8, HSPA9, HSP90AA1, IFNG, JUN, KPNA2, KPNA3, KPNA4, KPNA5, TNPO1, LTBP2, NUP88, NUP98, OR1D2, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX14, RAB6A, RAB27A, RAN, RANBP2, SIX3, SLC11A1, STAT3, TSC2, YWHAZ, RAB7A, NUP214, AP3B1, AKR1C3, BECN1, RASSF9, TRIP11, ZFYVE9, PICK1, AKAP12, NUP155, IPO13, NUP93, ZFYVE16, TOMM20, AP1M2, KATNB1, TXNIP, GIPC1, AFG3L2, TOMM34, OS9, CDC37 |
1936 | GO:0070588 | 0.03 | 1.61 | 26.76 | 35 | 72 | calcium ion transmembrane transport | ANXA5, ATP2A1, ATP2B1, ATP2B2, ATP2B3, CACNA1A, CACNA1B, CACNA2D1, CCR5, DDIT3, GAS6, GPM6A, XCR1, GRIN2A, HTR2C, ITGAV, ITPR1, ITPR2, P2RX1, P2RX7, PSEN1, RYR1, RYR3, CCL21, SLC8A3, TRPC3, TRPC4, TRPC5, TRPM2, TRPV1, TRPA1, SLC24A1, CACNG2, CHERP, IL1RAPL1 |
1937 | GO:2001020 | 0.02 | 1.61 | 32.16 | 42 | 86 | regulation of response to DNA damage stimulus | ABL1, ATM, ATR, BCL2L1, BRCA1, CASP9, CD44, CDK9, CDKN2A, CHEK1, CLU, CRY1, DDX5, DYRK1A, EYA1, EYA3, HIC1, ING2, MGMT, OGG1, PCNA, PPP4C, PRKCD, RAD51, RAD52, RPA2, RPS3, SETMAR, SNAI1, TP73, TPT1, TWIST1, UBE2V2, WHSC1, HMGA2, CUL4A, RNF8, EEF1E1, BCLAF1, FEM1B, RAD51AP1, CHEK2 |
1938 | GO:0048878 | 0.01 | 1.60 | 42.68 | 56 | 118 | chemical homeostasis | XIAP, TSPO, CCK, CNR1, COMT, CPS1, CRY1, CRY2, CTSH, CYP11B1, DBH, DCN, FGF7, SLC37A4, GCGR, GJA5, FFAR1, IDUA, IGFBP5, KCNA1, KCNH2, KCNJ10, KDR, SMAD7, OTC, PARK2, PCK1, PDE3B, PDK4, PRCP, PTHLH, PYGL, RPS6, SCN5A, SCN7A, SCN10A, SFRP4, SFTPD, SLC2A4, SLC9A2, SLC9A3, SLC9A5, SLC12A1, SLC16A1, SLC34A1, SOD2, STAT3, STK11, HNF1A, UPK3A, PICALM, TRIM24, STXBP5L, HCN4, SLC9A6, CORIN |
1939 | GO:0001818 | 0.01 | 1.60 | 44.51 | 58 | 119 | negative regulation of cytokine production | ANGPT1, ANXA1, APOA1, AXL, BCL3, BPI, BST2, BTK, TSPO, CDH3, CRYBA1, CYLD, F2RL1, FBLN1, GAS6, GATA6, GHSR, IFNA2, IFNG, IL10, IL12B, IL13, IDO1, INHA, LTF, PCBP2, PPM1B, PRG2, PTGER4, RAC1, RARA, RELB, XCL1, CX3CL1, SFTPD, SLC11A1, TNFAIP3, TWIST1, TNFSF4, TNFRSF4, UBB, UBA7, SCGB1A1, WNT11, TRIM25, EPX, TAX1BP1, RPS6KA4, ATG12, IL1RL1, KLF4, ATG5, NR1H4, NUTF2, PRG4, TRAIP, KLF2, GPNMB |
1940 | GO:0016310 | 0.00 | 1.60 | 198.67 | 257 | 555 | phosphorylation | ADAM10, ADAR, ADARB1, AHSG, AMBP, AMHR2, BIRC5, APLP2, APOA1, APP, ARR3, ATP5C1, ATP5D, ATR, AXL, BARD1, BCR, BDKRB2, BLK, BTK, BUB1B, CAMK4, CAV3, CCNE1, CCNG1, CDK11B, CDC25A, CDC25C, CDK2, CDK3, CDK4, CDK6, CDK8, CDKN2A, CHAD, CHEK1, CHKB, CHUK, CISH, CKM, CKS1B, CKS2, CLK1, CLK3, CCR5, COX4I1, COX8A, COX15, CREB1, ATF2, CRY1, CRYBA1, CSNK1G2, CSNK1G3, CSNK2A1, CSNK2A2, CTSH, DGKA, DGKB, DGKQ, DAPK3, DCN, DCX, DUSP1, DUSP4, DYRK1A, EIF2S1, EPHA2, ELK1, EPHA1, EPHA5, EPHB1, EPHB2, EPHB3, ERCC3, ERG, FBLN1, EFEMP1, FRK, FYB, GAK, GALK1, GALK2, GK2, GNAQ, SFN, GP1BA, GRK6, GPS2, GUCY2C, GUCY2F, GUCY2D, HCK, HHEX, FOXA2, HRC, HRG, HSPB1, IGBP1, IL12RB2, ILF3, IMPA1, INPP1, INSRR, ITGAV, KCNH2, KHK, LIMK1, LIPE, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, CIITA, NRTN, OXTR, PRDX1, PARK2, PCP4, CDK17, PDE4D, PDK4, PER1, CDK14, PHKA1, PHKA2, PHKB, PHKG1, PIK3C2B, PIK3C3, PI4KA, PIP4K2A, PPP1R1A, PPP2R1A, PRKCI, PRKCQ, MAPK8, PRKX, PRPSAP1, PSKH1, PTPN6, PTPRJ, PTPRR, ALDH18A1, RAC2, RAD51, RANBP2, RARA, RB1, RBL1, RBL2, RBM4, RGS2, RPS6KA1, RPS6KB1, RPS6KB2, SERPINB3, SDHC, SGK1, SKP1, SPINK1, SRMS, SRPK2, STAT4, AURKA, CDKL5, STYX, TAF7, TAZ, NR2F2, TNFAIP3, TOP1, NR2C2, TSC1, TSC2, TSG101, TWIST1, TYRO3, UQCRC1, UQCRC2, UQCRH, UVRAG, VRK1, VRK2, WEE1, SCG2, HMGA2, PIP5K1B, DYRK2, CUL1, PIK3R3, IKBKAP, DGKZ, PDXK, STK16, CDK13, DYNLL1, TNK1, RIOK3, DYRK4, TRIM24, CDKL1, KAT2B, KALRN, CDKL2, SOCS3, BAZ1B, PAPSS2, PAPSS1, DIRAS3, RGN, CCNE2, DYRK1B, DGKI, AURKB, STK17B, STK17A, SOCS6, KLF4, SLIT2, SLC9A3R1, EIF2AK3, ARHGEF6, PICK1, CDC42BPB, AATK, MAML1, NUAK1, FAM20B, XYLB, GNE, SH2D3C, SH2D3A, RANBP9, COL4A3BP, SGK2, ABI2, ATP6AP2, RNF41, CTDSPL, TRIB1, SPRY1, SPEG, BCKDK, TNIP1, PRDX4, ERN2, HEXIM1, ZMYND11, PRDX3, COPS5, PIM2, CIT, CDC37, STRAP, AKAP13 |
1941 | GO:1903747 | 0.03 | 1.60 | 29.17 | 38 | 78 | regulation of establishment of protein localization to mitochondrion | ACTL6A, BAD, BCL2, BID, BNIP3L, CDKN2A, CSNK2A2, CTSK, KAT2A, SFN, GPR26, NRG1, HNMT, HES1, ITGAX, PARK2, PPP3R1, MAPK8, RAC2, RNASE2, SREBF1, U2AF1, UBE2L3, YWHAZ, ZBTB17, FZD5, BAP1, RUVBL1, DYNLL1, CDKL2, BAG4, ATG13, FAM20B, BCL2L11, SAE1, PEMT, ARIH2, YWHAQ |
1942 | GO:1901657 | 0.00 | 1.59 | 75.55 | 98 | 202 | glycosyl compound metabolic process | ACACB, ACPP, ADSL, ADSS, AHCY, AK1, AK2, AK4, ALDOB, ALDOC, AMPD2, APRT, ARNT, ATP1A2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V0A1, ATP5O, BAD, TSPO, CDA, AKR1C4, COX4I1, COX8A, COX15, CTNS, CTPS1, DLG2, DLG3, DNMT1, DNMT3B, DPYD, DUT, TYMP, ENO2, ENO3, GAMT, GAPDH, GPD1, HIF1A, HMGCR, HPRT1, HSPA8, IGF1, IMPDH1, IMPDH2, INS, LDHA, LDHC, MAT2A, OGDH, P2RX7, PDC, PFKFB1, PFKFB2, PGAM1, PGAM2, PGK1, PGM1, PPP2R5D, PRKAA1, PRKAG1, PTGDR, SDHC, SLC34A1, SNCA, STAT3, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, TAZ, TYMS, UPP1, UQCRC1, UQCRC2, UQCRH, OGT, AKR1C3, PAPSS2, PAPSS1, ATP5J2, HDAC4, SLC25A13, PEMT, ATP5H, ATP5L, AHCYL1, SLC26A1 |
1943 | GO:0009163 | 0.03 | 1.59 | 27.68 | 36 | 74 | nucleoside biosynthetic process | ACACB, ADSL, ADSS, AK1, AK2, AK4, APRT, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, ATP5O, CDA, CTPS1, DUT, TYMP, HPRT1, IMPDH1, IMPDH2, LDHC, MAT2A, PDC, STAT3, TYMS, UPP1, PAPSS2, PAPSS1, ATP5J2, SLC25A13, ATP5H, ATP5L, SLC26A1 |
1944 | GO:0043624 | 0.05 | 1.59 | 23.06 | 30 | 62 | cellular protein complex disassembly | ADD1, CAPG, CAPZA1, CAPZB, CCNB1, CFL2, EPS8, F2RL1, NRG1, HSPA8, PEX14, RDX, SGK1, SLN, SPAST, AURKA, TMOD1, VIL1, SYNJ1, SEMA5A, ARHGEF2, AURKB, DNAJC6, HDAC6, APC2, KATNB1, GAS2L1, AVIL, KIF2C, STMN2 |
1945 | GO:0030324 | 0.04 | 1.59 | 23.84 | 31 | 64 | lung development | ACVR2B, ARG1, BMPR1A, BMPR2, CRH, CTGF, DHCR7, EIF4E, EIF4EBP1, EP300, GPC3, HMGCS2, HES1, HSD11B1, IGFBP5, ITGA3, KDR, LAMA5, PGR, PTHLH, PTN, SFTPD, SIM2, SP1, SPARC, SREBF1, WNT11, ALDH1A2, ADAMTS2, FSTL3, PDPN |
1946 | GO:0010876 | 0.00 | 1.58 | 69.57 | 90 | 186 | lipid localization | ABCA1, ABCA2, ABCA3, ABCA4, ACACB, AGTR1, AGTR2, AKT2, ALB, ABCD1, ANXA1, APOA1, APOH, BDKRB2, BMP6, TSPO, C3, VPS51, CD36, CFTR, AKR1C4, CLU, CPT1B, CPT2, CRH, CRP, CRY1, ACE, DRD3, FABP6, ACSL1, ACSL3, ACSL4, B4GALNT1, GALR1, GDF9, GM2A, GOT2, HEXB, IL1B, ITGAV, KCNN4, LCAT, LIPC, NTSR1, OSBP, P2RX4, P2RX7, P2RY2, PARK2, SERPINA5, ATP8B1, PRKCD, PSAP, ABCD3, RXRA, SLC10A1, SLC10A2, SLCO2A1, SLCO1A2, STAR, STAT5B, TAC1, TMF1, NR1H2, NRIP1, SLC10A3, FZD4, SOAT2, DGAT1, SLC9A3R1, LIPG, ABCG1, OSBPL2, NR1H4, ATP9A, COL4A3BP, ABCC4, SIGMAR1, ABCA7, ABCA10, ABCA9, ABCA8, ATP8A1, SLC25A17, SLCO1B1, CFHR4, SLC27A5, SLC27A4, SLC27A2 |
1947 | GO:0006259 | 0.00 | 1.58 | 58.64 | 76 | 159 | DNA metabolic process | PARP4, ANXA1, BACH1, CBS, CCNH, CDC5L, CENPF, CSNK1D, CTGF, DDB2, GADD45A, DDX1, DNMT3B, DNTT, EP300, EYA4, ERCC3, ERCC5, ERCC6, EYA2, FANCA, FANCC, FANCD2, FANCE, FANCB, FANCF, FANCG, GNAS, HMGN1, ATXN3, NTHL1, PPP5C, MAPK8, RAD23B, RAN, RLF, SMARCA1, SUMO3, TP73, TYMS, UBA7, UVRAG, XPA, XPC, TRIM25, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, SMARCA5, FKBP6, PARG, COPS3, CDC14B, BANF1, ALKBH1, MBD4, HIST1H3F, BAZ1B, COPS2, PICK1, CHD1L, KDM4A, USP3, RBX1, PPIE, MAD2L2, SLC30A9, CTCF, COPS8, ASCC3, COPS6, COPS5, PAPD7 |
1948 | GO:0042592 | 0.00 | 1.58 | 50.65 | 66 | 142 | homeostatic process | ADAR, ANG, AXL, TNFRSF17, KRIT1, CFL2, CLCN6, CLNS1A, CYBB, DNASE2, E2F4, EMX1, FANCC, FEN1, GAA, HCLS1, IDE, IFNG, INHA, KCNN4, KIT, SMAD1, PCNA, PDE4B, PRIM2, RAD51, RAD51D, RAG1, RAG2, RB1, UPF1, RFC3, RFC4, RFC5, RPA2, RPA3, RPS19, SOS1, SOS2, SP1, SP100, TYRO3, TUSC3, HIST1H4I, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, FOXN1, IKBKG, TNFSF14, AIFM1, CCNB2, CHST3, DCLRE1A, BCL2L11, PDIA6, IKZF1, KLF2, PRDX4, SIVA1, TNFSF13B, PDIA5 |
1949 | GO:0010822 | 0.02 | 1.58 | 35.53 | 46 | 95 | positive regulation of mitochondrion organization | ACTL6A, ADRB2, BAD, BAX, BCL2, BID, BNIP3, CSNK2A2, CTSK, DCN, KAT2A, SFN, GPR26, NRG1, HIF1A, HNMT, HES1, ITGAX, KDR, OPA1, PARK2, PPP3R1, MAPK8, RAC2, RNASE2, U2AF1, UBE2L3, YWHAZ, ZBTB17, FZD5, BAP1, RUVBL1, DYNLL1, BECN1, HRK, TNFSF10, CDKL2, ATG5, ATG13, FAM20B, BCL2L11, SAE1, PEMT, ARIH2, SIVA1, YWHAQ |
1950 | GO:0034220 | 0.00 | 1.58 | 132.01 | 170 | 358 | ion transmembrane transport | ABCA1, ACACB, ANXA5, ANXA6, AQP5, AQP6, AQP7, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP4B, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, ATP5O, ATP7B, CHRNB2, CHRNB4, CLCA1, CCR5, CNGA1, COX4I1, COX5B, COX6A1, COX6B1, COX7A1, COX7C, COX8A, COX15, CPT1B, CPT2, CYB5A, DDIT3, TSC22D3, GABRA4, GABRA5, GABRA6, GABRE, GABRG1, GABRR1, GABRR2, GAS6, GLRA1, GLRA2, GPM6A, XCR1, GRIA1, GRIA4, GRID1, GRID2, GRIK3, GRIN2A, HTR2C, HTR3A, ITGAV, ITPR1, ITPR2, KCNK2, KCNK3, KCNN1, KCNN4, SLC11A2, P2RX1, P2RX3, P2RX4, P2RX5, ATP8B1, PSEN1, RAF1, REST, RHAG, RHCE, RHD, RYR1, RYR3, S100A6, SCNN1A, SCNN1B, SCNN1G, CCL21, SGK1, SLC1A3, SLC1A6, SLC1A7, SLC4A1, SLC5A5, SLC6A6, SLC6A7, SLC7A1, SLC7A4, SLC8A3, SLC9A2, SLC9A3, SLC9A5, SLC11A1, SLC12A1, SLC12A2, SLC12A3, SLC13A1, SLC16A1, SLC20A1, SLC22A3, SLC22A2, SLC22A5, ABCC8, TRAPPC10, TRPC3, TRPC4, TRPC5, TRPM2, UBB, UQCRC1, UQCRH, TRPV1, SLC30A2, SLC30A3, SLC30A4, SLC7A5, SLC25A12, SLC4A4, SLC5A6, TRPA1, ATP6V0D1, SLC16A6, SLC16A5, SLC16A4, COX7A2L, SLC24A1, SLC16A7, SLC22A6, SLC22A8, SLC4A7, SLC4A8, ATP6V1G1, ATP5J2, CLCA2, PIEZO1, SLC12A6, ABCC9, SGK2, SLC25A13, SLC25A15, SLC35B1, KCNMB2, ATP8A1, SLC30A9, ATP5H, SLC25A17, SLC9A6, CHERP, SLC34A2, ATP5L, SLC26A1, UQCR11, SLC27A5, WWP1, SLC7A9, IL1RAPL1 |
1951 | GO:0015758 | 0.02 | 1.58 | 34.78 | 45 | 93 | glucose transport | AKT2, C3, CREBL2, EDNRA, ESR1, G6PC, SLC37A4, GPC3, FFAR3, NRG1, IGF1, IL1B, INS, NUP88, NUP98, PRKAA1, PRKCI, PRKCZ, RANBP2, RPS6KB1, RTN2, SORT1, SLC2A1, SLC2A3, SLC2A4, SLC2A5, SLC5A2, STXBP3, HNF1A, TSC1, TSC2, VIL1, NUP214, AAAS, CLTCL1, PIK3R3, PEA15, NUP155, NUP93, C2CD5, SORBS1, NUP50, ARPP19, NUPL2, CAPN10 |
1952 | GO:0032990 | 0.00 | 1.58 | 245.72 | 313 | 657 | cell part morphogenesis | ABL1, ABL2, ACTB, ACTG1, ADAM10, ANGPT1, APP, ARAF, ARHGAP4, RERE, ATOH1, ADGRB1, BAX, BBS1, BBS2, BBS4, BCL2, BCL2L1, BMPR2, CACNA1A, CACNB3, CACNB4, CALM1, CALM3, CAMK2A, CCK, CD72, CDC42, CHN1, CHRNB2, AP2S1, CLU, CLTA, CNP, COL3A1, COL4A3, COL4A5, COL5A2, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2RB, CSNK1D, CSNK2A1, CSNK2A2, CTNNA2, CTNND2, CYLD, DCC, DCX, DLG3, DLX5, DNM1, DNAH5, DNM2, DPYSL3, EPYC, HBEGF, ECM2, DUSP5, E2F4, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EPHA2, EMX1, CTTN, EPHA1, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, ERBB2, EREG, ETV4, EXT1, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FYN, GDI1, GFRA1, GOLGA4, GPM6A, GRB2, GRIN2A, ARHGAP35, NRG1, ONECUT1, HPRT1, HSPA8, HSP90AA1, HSP90AB1, IFRD1, IL2RA, ILK, ISL1, ITGA1, ITGA5, ITGA9, ITGAV, ITGB1, KIF5A, KIT, KRAS, LAMA5, ABLIM1, LIMK1, CAPRIN1, MAP6, MARK3, KITLG, SEPT2, SLC11A2, NRCAM, NRTN, NTF3, NTF4, NTRK1, NTRK2, NTRK3, NTN3, OGN, OMG, OTX2, PEBP1, PARK2, PCM1, ENPP2, PPP5C, PRKCQ, PRKCZ, PSPN, RELN, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, PTPRA, PTPRD, PTPRM, RAC1, RAC2, RAF1, RAP2A, RASA2, RFX3, RNF6, RPGR, RPL24, RPS6KA1, RREB1, RYK, S100A6, S100B, SCN5A, SDC2, SDCBP, SEMA3F, SGK1, SHC1, SIAH1, STIL, SLIT3, SOS1, SOS2, SPAG1, SPAST, SRF, TROVE2, AURKA, CDKL5, STK11, STXBP1, SUPV3L1, SYT1, SYT4, CNTN2, TBCE, DYNLT1, TNR, TOP2B, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, VIL1, WEE1, SEMA3B, FGF23, RND2, USP9X, PICALM, CUL3, CNTNAP1, GAS7, CDC14A, KLF7, UNC5C, NUMB, DYNLL1, PEA15, RAB11A, NRP2, NRP1, ARHGEF7, CPNE1, PHOX2B, WASF1, RPS6KA4, KALRN, SEMA5A, ATP6V0D1, ARHGEF1, NUMBL, SNAP29, SLIT2, NRXN3, NRXN1, ATG5, ONECUT2, PSMF1, NRG2, AATK, FEZ2, RAPGEF2, RIMS2, SEMA3E, IFT140, IST1, CUL7, ARHGEF11, FARP2, PSMD6, RBX1, ABI1, RANBP9, COL4A3BP, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, FARP1, WASF2, PSME3, PSMD14, ABCC4, SEMA3A, SPON2, VAV3, BAIAP2, SLC9A6, CAP1, STK25, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, ATG7, ARPC1A, DPYSL4, AVIL, TBR1, CHL1, SEPT9, FRS3, RAB10, AFG3L2, VAX1, CIT, KIF3A, IL1RAPL1 |
1953 | GO:0051983 | 0.05 | 1.57 | 23.19 | 30 | 62 | regulation of chromosome segregation | ATM, ATRX, BUB1B, CCNB1, CDC20, CDC27, CDC42, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, PTEN, RB1, SFPQ, TTK, ZNF207, CUL3, BECN1, CDC23, CDC16, ZW10, AURKB, DLGAP5, ANAPC10, MAD2L2, CTCF, KIF2C, UBE2C, CIT |
1954 | GO:0065003 | 0.01 | 1.57 | 51.67 | 67 | 143 | macromolecular complex assembly | ABCA1, ADAR, APOA1, ATM, ATR, BICD1, CIRBP, CLNS1A, DDX1, DDX6, DYNC1H1, EIF2S3, ACSL3, GRB7, EIF3E, LCAT, CNOT2, RAD51C, RAD51B, RAD51D, RAD52, RB1, RPL3, RPL3L, RPL5, RPL10, RPL11, RPL24, RPL38, RPS27, SRSF1, SRSF5, SRSF6, SFSWAP, SNRPC, SNRPD1, SNRPD2, SNRPE, SNRPF, SOX12, SRPK2, TAF2, TAF7, USP4, NR1H2, XRCC2, SOAT2, PRPF18, DENR, EIF3G, EIF3J, SRSF9, DGAT1, CDC123, TAF1B, PRPF3, SCAF11, DDX23, ABCA7, CD2BP2, EIF3M, USP39, TXNL4A, SF3A3, PSIP1, STRAP, DDX20 |
1955 | GO:0010608 | 0.00 | 1.57 | 105.10 | 135 | 281 | posttranscriptional regulation of gene expression | AARS, ACO1, ADAR, AKT2, ANG, APP, ATF4, BCL3, ZFP36L2, CD28, CDK4, CIRBP, DAPK3, DAZ1, DDX1, DDX6, DHX9, DIO2, DKC1, EEF2, EIF2S1, EIF2B1, EIF4A1, EIF4E, EIF4EBP1, EIF4G1, EIF4G2, EIF5, EIF5A, ELAVL1, EPRS, ERBB2, ETF1, PTK2B, GAPDH, GRB7, HNRNPC, HNRNPD, HSPA8, HSPB1, IGF1, IGFBP5, ILF3, EIF3E, TNPO1, CAPRIN1, SMAD1, SMAD3, CNOT2, YBX1, PA2G4, PER1, PRKCD, EIF2AK2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTAFR, PURA, RAN, RARA, RBM4, UPF1, RGS2, RPL38, RPS3, RPS4X, RPS6KA1, RPS6KB1, RPS6KB2, RXRA, S100A9, SET, SLC11A1, SRP9, TNFRSF1B, TSC1, UBB, UCN, SCGB1A1, VIP, EIF4H, YWHAZ, ZFP36, NUP214, ANP32A, MAPKAPK5, KHSRP, EIF4EBP3, EIF3G, EIF3J, EIF4G3, CDC123, EIF2B3, EIF2B2, EIF2B5, RQCD1, CNOT8, QKI, EIF2AK3, PSMF1, EIF5B, EIF4A3, PSMD6, RBM8A, TRAP1, PSME3, EIF1, PSMD14, EIF1B, PRG3, EIF3M, USP16, IGF2BP3, KHDRBS1, CDC37 |
1956 | GO:0032269 | 0.00 | 1.57 | 108.97 | 140 | 295 | negative regulation of cellular protein metabolic process | ABL1, ADARB1, ANGPT1, BAX, BDKRB2, BMP4, BRCA1, TSPO, CALM1, CALM3, CAV3, CDKN1A, CHAD, CISH, CRY1, CRY2, CRYBA1, DCN, GADD45A, DLG2, DLG3, DNMT1, DNMT3B, DUSP4, DUSP5, EPHA1, F2RL1, FBLN1, FYN, GFRA2, GNAQ, GP1BA, GPS2, RAPGEF1, HHEX, HMGCR, HSPB1, IGF1, IGF1R, IGFBP3, IL1B, ILK, JARID2, JUN, LIMK1, SMAD6, SMAD7, NTF3, NTRK3, P2RX7, PARK2, PCP4, PDE4D, PER1, PPP1R1A, PPP2R1A, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCE, PRKCZ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTPN1, PTPN6, PTPRJ, PTPRR, RB1, RGS2, SET, SNRNP70, TAF7, NR2F2, TNFAIP3, TP73, TSC2, TWIST1, UBB, UCN, USP4, AKAP1, CUL3, OGT, URI1, HDAC3, KAT2B, SOCS3, RGN, LATS1, ITGB1BP1, SOCS6, SLIT2, SLC9A3R1, ATG5, BAG4, KDM4A, PPP1R26, PSMD6, RANBP9, FARP1, PSME3, PSMD14, CTDSPL, TRIB1, SPRY1, TNIP1, HMG20B, PIAS3, CD2BP2, CRTAP, SEMA4D, ATG7, HEXIM1, ZMYND11, GLMN, STRAP |
1957 | GO:0016485 | 0.01 | 1.56 | 44.24 | 57 | 119 | protein processing | A2M, ADAM10, AEBP1, BIRC2, BIRC3, XIAP, BIRC5, BGLAP, SERPING1, C3, C7, CD59, CGA, CLN5, CPD, CTSE, CTSV, CTSZ, ACE, F2, F7, F10, FSHB, GAS1, GAS6, GZMH, IDE, IHH, CD46, P2RX7, PCSK6, PCSK5, CFP, PIK3C3, PRKACB, PROC, PSEN1, PTHLH, CNTN2, TMPRSS2, TSG101, TSHB, UBB, UQCRC1, UQCRC2, VTN, PROZ, RHBDL1, PCSK7, ADAMTS3, ADAMTS2, TMEM59, ATP6AP2, ZMPSTE24, CORIN, AFG3L2, ADAMTS13 |
1958 | GO:0007605 | 0.03 | 1.56 | 30.29 | 39 | 81 | sensory perception of sound | ATP2B2, ATP6V1B1, CHRNB2, COL1A1, COL4A3, COL11A1, CRYM, DFNA5, DIAPH1, DNM1, EYA4, EYA1, GABRA5, GPX1, HEXB, ICAM1, KCNE1, KCNQ1, KIT, PAX3, ATP8B1, RPL38, SCN8A, SIX1, SLC1A3, SLC12A2, SOD1, SOX2, TBL1X, ZNF354A, TUB, UCN, USH2A, CLRN1, WFS1, FZD4, SLC9A3R1, GJB6, KPTN |
1959 | GO:0035148 | 0.03 | 1.56 | 30.29 | 39 | 81 | tube formation | ADM, APAF1, BBS4, BMP4, EDA, FZD2, KAT2A, ARHGAP35, HIF1A, OPA1, PAX3, PFN1, PRKACB, RALA, RARA, SALL1, SDC4, STIL, SIX1, SOX9, SOX11, SPINT1, ST14, TSC1, TSC2, TULP3, TWIST1, KDM6A, ZIC2, PAX8, FZD6, ITGB1BP1, HAND1, ZEB2, BCL2L11, SEC24B, DEAF1, EDAR, GLMN |
1960 | GO:0080135 | 0.03 | 1.56 | 30.22 | 39 | 82 | regulation of cellular response to stress | ACTL6A, ADRB2, ATP6V0A1, BAX, BDKRB2, BNIP3, BNIP3L, TSPO, CSNK2A2, CTSK, DCN, CTTN, KAT2A, KCNK2, KDR, ATXN3, PAFAH1B2, PIP4K2A, SDF2, SGTA, SREBF1, TSC1, U2AF1, ZBTB17, RAB7A, EPM2A, OGT, RUVBL1, BECN1, USP13, USP14, ARHGEF2, RAB33A, ATG5, FEZ2, TRIM13, ATG7, USP19, OS9 |
1961 | GO:0006974 | 0.00 | 1.56 | 87.32 | 112 | 236 | cellular response to DNA damage stimulus | ACTL6A, PARP4, XIAP, BACH1, BARD1, CCNH, CDK3, CHD2, CSNK1D, CTLA4, DDB2, DDIT3, DDX1, ERCC1, EYA4, ERCC3, ERCC4, ERCC5, EYA2, FANCA, FANCC, FANCD2, FANCE, FANCB, FANCF, FANCG, FEN1, HMGN1, HMGA1, KPNA2, ATXN3, TONSL, NTHL1, PPP5C, MAPK8, PSEN1, RAD21, RAD23B, RAD51C, RAD51B, RAD51D, RBBP6, UPF1, REV3L, RFC3, RFC4, RFC5, RPA3, SFPQ, SGK1, SUMO3, SSRP1, STK11, SUV39H1, TOP2A, UBA7, UBE2E2, SUMO1, UNG, UVRAG, XRCC2, XRCC4, XRCC5, YY1, TRIM25, SHFM1, CHAF1B, HIST1H4I, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, PARG, IKBKG, COPS3, RUVBL1, ALKBH1, HERC2, MBD4, BAZ1B, SMC3, EXO1, COPS2, RECQL5, RECQL4, CHD1L, KDM4A, KIAA0101, NUAK1, DCLRE1A, USP3, RBX1, REC8, RAD50, DDX39A, RBM14, PPIE, VAV3, SLC30A9, RNASEH2A, USP16, RUVBL2, COPS8, ASCC3, COPS6, COPS5, PAPD7, SUPT16H |
1962 | GO:0034654 | 0.00 | 1.55 | 812.95 | 987 | 2179 | nucleobase-containing compound biosynthetic process | ABCA1, ABCA2, ABL1, ACTL6A, ACTN1, ACVR1, ACVR2A, ACVR2B, ACVRL1, ADCY3, ADCY5, ADCY6, ADCY9, ADM, ADRA2A, ADRB2, AEBP1, JAG1, AGTR2, NR0B1, AKT2, ALK, ALX3, AMPD1, AMPD2, ANG, ANXA3, BIRC2, XIAP, BIRC5, APLP1, APP, PHOX2A, ARNT, ARNTL, ASCL1, ASCL2, ATF4, RERE, ATOH1, ATRX, AVP, AVPR2, BACH1, CCND1, BCL3, BCL7A, PRDM1, BMI1, BMP1, BMP3, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, BRCA1, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTG1, BTK, CALCR, CALM1, CALM3, CAMK4, CAMK2A, CAT, RUNX2, RUNX1T1, CBFB, CBL, CCNC, CCNE1, CCNH, CCNT1, CCNT2, CD3D, CD28, CD80, CD86, TNFSF8, CD36, CD38, CD81, CDK11B, CDC5L, CDH1, CDK2, CDK8, CDK9, CDKN1A, CDKN2A, CDX1, CDX2, CDX4, CEBPE, CENPB, CENPF, CGA, CHD1, CHD2, CHD3, CHD4, CHEK1, CHUK, CLU, COL1A1, COX4I1, COX5B, COX6A1, COX6B1, COX7C, COX8A, CREB1, ATF2, CREBL2, CRH, CRX, CRY1, CRY2, CRYM, CSNK2A1, CSNK2A2, CSTF3, CTGF, CTH, CTNND2, CYLD, DAB2, DGKQ, DAPK3, DCN, DDIT3, DDX1, DDX5, DHFR, DKC1, DLX5, DLX6, DNM2, DNMT1, DNMT3B, DNTT, DRD3, DRD5, ARID3A, RCAN1, TSC22D3, DTYMK, DUSP1, E2F2, E2F4, E2F6, E4F1, EBF1, ECM1, EDA, S1PR1, LPAR1, EDNRA, EFNA1, EGR2, EGR3, EGR4, ELAVL2, ELK1, EMX1, EMX2, EN1, EP300, EPHA5, ERBB2, EREG, EYA4, ERCC3, ERCC6, ERF, ERG, ERN1, ESR1, ESRRG, ETS1, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA1, EYA2, EYA3, EZH1, F2R, F2RL1, PTK2B, FAU, FBN1, EFEMP1, FGF4, FGF7, FGFR3, FGFR4, FLI1, FRK, FSHB, FSHR, NR5A2, NR5A1, FZD2, GABPA, GALR1, GAS6, GATA4, GATA6, GCG, KAT2A, NR6A1, GDF9, GFI1, GHRH, GHRHR, GPC3, GLP1R, GLS, GMDS, GNAL, GNAS, SFN, GPS2, GPX2, ARHGAP35, GRM8, GSC2, GTF2F1, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, GUCA1A, GUCA1B, GUCA2A, GUCA2B, GUCY1B3, GUCY2C, GUCY2F, GUCY2D, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, H2AFZ, HBE1, HCK, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIF1A, HIP1, HIVEP2, ZBTB48, HLF, HLX, HMGN1, HMGA1, NR4A1, HMX1, HMX2, FOXA2, HNF4G, ONECUT1, HNRNPD, HOXC10, HOXC11, HOXD3, HOXD8, HOXD9, HOXD10, HOXD11, HOXD12, PRMT2, HES1, HSF4, HSPA8, HTR2C, ICAM1, IFI16, SP110, IFNA2, IFNG, IGBP1, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL1B, IL10, IL17A, ILF3, ILK, ING2, INS, INSIG1, INSL3, IRAK1, IRAK2, IRF1, IRF2, IRF5, ISL1, ITGA3, JARID2, JUN, JUND, KCNK2, KIT, KRAS, AFF3, ABLIM1, LMO1, LTF, LUM, EPCAM, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MEOX2, CIITA, ATXN3, AFF1, FOXO4, CITED1, PPP1R12A, DRG1, RPL10A, TONSL, CNOT2, NRL, YBX1, NTF3, NTRK1, NTRK2, NTRK3, NUP88, NUP98, NVL, OAS2, OGG1, SIX6, ORC1, ORC2, OTX1, OTX2, OVOL1, P2RY1, P2RY11, PA2G4, PCSK6, PRDX1, SERPINE1, PALM, PAM, PARK2, PAWR, PAX3, PAX4, PAX9, PBX1, PCK1, PCNA, CHMP1A, PDE8A, PER1, PEX14, PF4, PFAS, PFDN1, ATP8B1, PFN1, PGM3, PGR, PHF2, PIM1, PRRX1, PPID, PPM1A, PPP1R8, PPP2R1A, PPP3R1, PPP5C, PRIM2, PRKAA1, PRKAG1, PRKAR1A, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK8, EIF2AK2, PRPSAP1, RELN, PSEN1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PTAFR, PTEN, PTGER4, PTGIS, PTHLH, PTMA, PURA, RAD21, RAF1, RAN, RANBP2, RARA, RARB, RB1, RBL1, RBL2, RCVRN, RELB, DPF2, REST, REV3L, RFC3, RFC4, RFC5, RFX1, RFX2, RFX3, RFXAP, RGS12, RHEB, RLF, RNF6, RPA2, RPA3, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS6KA1, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, RREB1, RRM1, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A12, SALL1, SATB1, XCL1, TRAPPC2, SET, SFPQ, SFRP4, SFRP5, SRSF1, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SFSWAP, SGK1, SHMT1, SIM2, SIX1, SIX3, SLC9A1, SLC11A1, SMARCA1, SMARCA2, SMARCA4, SMARCC2, SMARCD1, SMARCD3, SMARCE1, SNAI1, SNAPC1, SNAPC2, SNAPC3, SNCA, SNRPE, SNRPF, SOD2, SOX1, SOX2, SOX3, SOX9, SOX10, SOX11, SOX12, SP1, SP4, SP100, UAP1, SPIB, SREBF1, SRF, SRY, TRIM21, TROVE2, SSRP1, STAT1, STAT2, STAT4, STAT5B, STAT6, SUPT4H1, SUV39H1, TAF2, TAF4B, TAF5, TAF6, TAF7, TAF10, TAF13, TAL1, TAL2, TBL1X, TBP, HNF1A, ZEB1, ZNF354A, NR2F1, NR2F2, KLF10, TMF1, TMPO, TNFAIP3, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TSC1, TSC2, TSG101, TTF1, TULP3, TWIST1, TNFSF4, TNFRSF4, U2AF1, UBB, UBA7, UBE2D2, UBE2L3, UBE3A, SUMO1, UBTF, UCN, UCP1, SCGB1A1, UGDH, UGP2, NR1H2, USF1, VAV1, VIP, VIPR2, WFS1, WHSC1, WNT1, WNT2, WNT11, XRCC5, YY1, YWHAZ, ZFP36, ZFP37, ZFPL1, ZIC1, ZIC2, ZNF3, ZNF711, ZNF7, ZNF8, CNBP, ZNF708, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZSCAN21, ZNF41, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF91, ZNF99, ZNF124, ZNF132, ZNF136, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF217, ZNF223, ZNF224, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, ZXDA, PRDM2, CSDE1, PAX8, FZD5, BRPF1, ARHGEF5, ZNF212, BRD3, NUP214, CSRP3, FOSL1, FGF23, AAAS, HMGA2, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, USP9Y, HIST1H4I, PICALM, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, CUL4A, CUL3, CUL2, FOXN1, KLF11, SMARCA5, OGT, ITGA8, IKBKG, IKBKAP, HAT1, GAS7, CBX4, CAMK1, PIR, BLZF1, MAPKAPK5, KHSRP, STK16, RGS20, RUVBL1, KLF7, CDK13, RFXANK, TP63, CHRD, DYNLL1, SRSF9, TRADD, EDF1, URI1, EED, RNGTT, RIPK1, RIPK2, SUCLG1, TRIM24, SAP30, HESX1, CFLAR, HDAC3, TSC22D1, KAT2B, PER3, TAX1BP1, BUD31, CPNE1, PHOX2B, KYNU, HIST1H3F, HIST1H2AG, USP13, RPS6KA4, TNFSF18, TAF1C, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, RPL14, USP2, RGN, PDLIM1, RQCD1, CBFA2T2, DYRK1B, CTDP1, COX7A2L, ARHGEF2, DDX21, SLC33A1, AURKB, CCPG1, ITGB1BP1, ZNF235, KLF4, COPS2, TRIP11, HMGN3, GTF3C5, GTF3C4, GTF3C3, CNOT8, RPL23, CER1, CIAO1, RECQL5, ZRANB2, HAND1, ZNF264, EIF2AK3, FHL5, AKAP6, ATG5, ONECUT2, LITAF, TBPL1, ZNF254, GABBR2, CLOCK, SOX13, RBM39, AKAP12, RNF14, ABCG1, GUCA1C, NUP155, ZNF592, CTR9, ZNF516, KDM4A, VGLL4, NUP93, BZW1, ST18, ZNF646, SETD1A, HDAC4, ZFYVE16, KIAA0101, BCLAF1, MAML1, KEAP1, TSC22D2, RB1CC1, ARHGEF11, ZEB2, ZBTB24, ZNF518A, SETDB1, SUPT7L, RNF10, ZBTB5, RBM8A, NR1I3, NR1H4, NR1D2, RBX1, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, PREB, ZNF263, ZNF256, SORBS3, RNF41, CALCRL, TRIM13, OLIG2, TRIB1, ZNF443, DENND4A, IRX5, RAMP2, RAMP3, FSTL3, SAP18, APBB3, TNIP1, IKZF1, TRIM22, HMG20B, HMG20A, KLF2, CITED2, PIAS3, IFITM3, RAPGEF3, RBM14, PPIE, MAD2L2, SLC30A9, TRIM38, CAP1, CREB3, CARM1, SEMA4D, ZNF211, DEAF1, ATG7, SIVA1, CCT4, CCT2, ERN2, USP16, ERLIN1, HEXIM1, RBCK1, ARID3B, IVNS1ABP, TRIM16, TXNIP, DMRT2, KHDRBS1, CTCF, RRAGA, CERS1, TBR1, STAG2, RAI1, PHTF1, NUP50, ZMYND11, ZBTB6, ZNF234, ZNF266, ZNF273, ZNF275, RUVBL2, ARID5A, MALT1, BRD8, PAPOLA, RNPS1, PRDX3, YWHAQ, ASCC3, COPS5, CCDC85B, VAX1, GTF2A1L, PIM2, PAPD7, ADRM1, WWP1, WWP2, SOX30, HSF2BP, WDR5, NUPL2, PRDM7, PRDM5, KAT7, ERLIN2, SOX21, PSIP1, STRAP, ZNF277, SUPT16H, CHEK2, DDX20, RPL35 |
1963 | GO:0050707 | 0.04 | 1.55 | 28.80 | 37 | 77 | regulation of cytokine secretion | ABL1, ABL2, AGTR2, ALOX15B, ANGPT1, ANXA1, APOA1, CASP1, CASP5, CD58, CRP, CSF1R, F2R, F2RL1, FBLN1, FGR, GAS6, IFNA2, IFNG, IL1A, IL1B, IL10, IL17A, INS, P2RX7, PAEP, PRKCZ, PTGER4, CX3CL1, TWIST1, TNFSF4, TNFRSF4, IL1RL1, ATG5, NR1H4, TRIM16, GLMN |
1964 | GO:0045926 | 0.04 | 1.55 | 26.46 | 34 | 71 | negative regulation of growth | ACVRL1, AGTR2, ALOX15B, BCL2, BMPR2, BST2, BTG1, CD36, CDA, CDKN1A, CDKN2A, GDF9, GPC3, HIF1A, HRG, IFNG, IGFBP5, IL10, IL12B, SMAD3, PPP2R1A, PTPRJ, SIPA1, SLIT3, SMARCA2, SMARCA4, STK11, TRO, WNT11, TNK1, ADAM15, EI24, GAS2L1, CCDC85B |
1965 | GO:0016477 | 0.00 | 1.55 | 61.38 | 79 | 170 | cell migration | ABL2, JAG1, ANG, APOA1, RERE, BTG1, TSPO, CD151, VCAN, CSPG4, CTGF, CTNNA2, DPP4, EFNA1, EFNB1, EMP2, CTTN, EPHA8, EPHB3, ERG, FAP, EFEMP1, FGFR4, FUT8, GPX1, HEXB, HES1, IL12B, ISL1, ITGB4, KRT2, LAMA3, LAMA4, LAMA5, NRTN, P2RY1, PAX3, PIK3C2B, PRCP, PRKCI, PRKCZ, PRKX, PSG2, RAB1A, S100A2, SCNN1B, SDC2, SDC4, SGK1, SIX3, SLC9A1, FSCN1, SOX10, SRMS, USP9Y, CUL3, FOXN1, SORBS2, DGKZ, UNC5C, DCHS1, TAOK2, CER1, CDC42BPB, SDC3, SLK, ZEB2, ELMO1, GAB2, GPC6, ARPC5, TSPAN1, ABI2, WASF2, TNK2, APC2, CAP1, GIPC1, BVES |
1966 | GO:0010605 | 0.00 | 1.55 | 183.83 | 234 | 508 | negative regulation of macromolecule metabolic process | ABL1, ACVRL1, ADARB1, ADRA1B, AHSG, AMBP, ANGPT1, APCS, APLP2, APP, ATM, ATR, AVP, BAX, BDKRB2, BMPR2, BRCA2, BST2, BUB1B, TSPO, C3, CALM1, CALM3, CAV3, SERPINH1, CD44, CDC20, CDC27, CHAD, CISH, CLU, COL4A3, COL6A3, CRYBA1, CSNK2A1, CSNK2A2, CST6, DCN, GADD45A, DFFA, DHCR24, DLG2, DLG3, DPEP1, HBEGF, DUSP1, DUSP4, DUSP5, ECM1, SERPINB1, EPHA1, ERCC1, ERCC4, F2, F2RL1, FBLN1, FGA, GFRA2, GHSR, GPC3, GNAQ, SFN, GP1BA, GPX1, RAPGEF1, GRIN2A, SERPIND1, HGF, HMGCR, HNRNPC, HRG, DNAJB2, HSPB1, HSP90AB1, IDE, IGF1, IGFBP3, IL10, ILK, INHA, INS, ITGAV, ITIH1, ITIH3, ITIH4, KCNK2, KNG1, LIMK1, SMAD6, TONSL, NTF3, NTRK3, OGG1, P2RX7, PEBP1, SERPINB2, SERPINA5, PCP4, PDE4D, PF4, PGGT1B, PI3, SERPINA4, SERPINB5, SERPINB8, SERPINB9, SERPINB10, SERPINB13, SERPINI2, PPP1R1A, PPP2R1A, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCE, PRKCZ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTGER4, PTPN1, PTPN6, PTPRJ, PTPRR, PZP, RAF1, RAG1, RENBP, RGS2, RPS6KA1, S100A11, SERPINB3, SERPINB4, SDCBP, SFTPD, SLPI, SNRNP70, SPINK1, SPINT1, SPOCK1, SERPINA7, TRAF2, TSC2, TTK, USP4, VIL1, VTN, WNT1, ZNF207, AKAP1, SMC1A, RECK, OGT, CDC23, SERPINB7, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR, KAT2B, CDC16, SOCS3, USP14, RGN, LATS1, SMC3, ZW10, ITGB1BP1, SOCS6, SLC9A3R1, ATG5, PSMF1, BAG5, BAG4, DHX34, PPP1R26, PSMD6, CASP8AP2, ACOT8, RANBP9, RAD50, FARP1, PSME3, PSMD14, PRG4, CTDSPL, SPRY1, TNIP1, TRIM22, ABCA7, HMG20B, ANAPC10, PIAS3, RAPGEF3, CD2BP2, CRTAP, ATG7, CERS1, STAG2, GIPC1, SPINT3, USP19, PRDX3, OS9, SPINK5, UBE2C, GLMN, CHEK2 |
1967 | GO:0010639 | 0.01 | 1.55 | 42.14 | 54 | 113 | negative regulation of organelle organization | ATM, ATRX, AVP, BCL2L1, BMP4, BNIP3, BUB1B, TSPO, CDC20, CDC27, CENPF, CHEK1, CSNK2A1, CSNK2A2, DNMT1, DNMT3B, DUSP1, ERCC1, ERCC4, FGFR3, GPX1, HGF, HMGA1, HNRNPC, IGF1, INSIG1, JARID2, OPA1, PHF2, PRKAR1A, RAD1, SET, SETMAR, SYT4, TAF7, TTK, TWIST1, UCN, XRCC5, ZNF207, CDC23, CDC16, ZW10, ATG5, BAG4, FEZ2, KDM4A, TOM1L1, RAD50, ANAPC10, ACAA2, MAD2L2, ATG7, UBE2C |
1968 | GO:0002250 | 0.02 | 1.55 | 40.59 | 52 | 109 | adaptive immune response | JAG1, BCL3, TNFRSF17, SERPING1, C1QA, C1QB, C1QC, C1S, C7, CAMK4, CD1B, CD6, CD7, CD8A, CD8B, CD86, CD79B, CLU, CR2, CTLA4, CTSH, GPR183, EMP2, ERCC1, PTK2B, FCGR1B, FGA, FYN, ICAM1, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IL13RA2, IL18, CD46, PIK3CB, PRKCD, RAB27A, RAG1, RELB, ADAM17, TSC1, LAT2, STX11, RNF8, EXO1, IL18BP, BTN3A3, CXCL13, BTN3A1 |
1969 | GO:0006898 | 0.02 | 1.54 | 39.82 | 51 | 107 | receptor-mediated endocytosis | ADRB2, ALB, AMBP, AMPH, APOA1, ARF6, ASGR1, CANX, CAV2, CD5, CD6, AP1S1, AP2S1, CLTA, ACKR2, COL1A1, COL3A1, DMBT1, CTTN, EPS15, FTL, GRN, HBA2, HP, HPX, HSP90AA1, ITGA4, LRPAP1, OLR1, ENPP2, ENPP3, PIK3CB, RAC1, SFTPD, SLC9A3, SPARC, SYT1, SYT5, TMPRSS2, HSP90B1, CUBN, CLTCL1, UNC119, PDLIM7, CD163, SNX17, DNAJC6, SNAP91, TNK2, PRG4, CAP1 |
1970 | GO:0044765 | 0.01 | 1.54 | 48.60 | 63 | 143 | single-organism transport | ACO1, ACTB, ACTG1, AHSG, ANXA11, APOH, BBS4, C3, CD3G, CDH3, CEBPE, CREBL2, CXADR, ESR1, FCGR1A, FCGRT, FCN2, GFAP, GPC3, GM2A, HPX, LIMK1, SERPINA5, PIGR, PIK3CB, PRKAA1, PTEN, PTK2, RAC1, RAP1GAP, RARA, RPS6KB1, SFTPD, ICAM5, TUB, TULP1, UBE3A, UPK3A, VAV1, VIL1, CUBN, SRPX, PIK3R3, PEA15, UNC119, ELMO1, OSBPL2, ABI1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, WASF2, SIGMAR1, SPON2, VAV3, BAIAP2, ARPC1A, SORBS1, ARPP19, CFHR4 |
1971 | GO:0044089 | 0.02 | 1.54 | 36.73 | 47 | 99 | positive regulation of cellular component biogenesis | APOA1, ATM, ATR, ADGRB1, ADGRB2, BBS4, CDC42, CLU, COL16A1, CTGF, LPAR1, EFNA5, EPHA1, EPHB1, EPHB2, EPHB3, F2RL1, HRG, KDR, KIT, LIMK1, SMAD3, CNOT2, NTRK1, NTRK2, NTRK3, OXTR, P2RX7, PIP4K2A, PTPRJ, S100A10, SDC4, SDCBP, SOX9, TAC1, TPBG, TSC1, TSG101, NR1H2, WNT11, ITGB1BP1, NRXN3, NRXN1, PDCD6IP, SORBS3, RAPGEF3, SEPT9 |
1972 | GO:0050673 | 0.03 | 1.53 | 34.46 | 44 | 93 | epithelial cell proliferation | APOA1, APOH, KLF9, KRIT1, CDK6, ATF2, CTSV, EDNRA, EREG, ERN1, FABP7, FAP, GPC3, SFN, HMGN1, IFNG, IGFBP3, IGFBP5, KIT, KRT2, TACSTD2, SMAD3, SERPINF1, PGR, SERPINB5, PIK3CB, PRKX, PSEN1, PTEN, PTPRM, RAP1GAP, RB1, RPS6KA1, SIX1, SOX2, SPARC, STAT1, STK11, NR2F2, FOXN1, ALDH1A2, RGN, ITGB1BP1, STRAP |
1973 | GO:1903531 | 0.04 | 1.53 | 30.64 | 39 | 82 | negative regulation of secretion by cell | ANGPT1, ANXA1, ANXA5, APOA1, BCR, CRHBP, CRY1, DRD3, F2R, F2RL1, FBLN1, GAS6, GHSR, HMGCR, IFNA2, IL1B, IL10, IL13RA2, INHA, INS, KCNJ11, PARK2, PDE4C, PTGER4, REST, CX3CL1, SNCA, SREBF1, STXBP3, ABCC8, SYT4, TNFSF4, TNFRSF4, UCN, FGF23, VAMP8, STXBP5L, NR1H4, IL1RAPL1 |
1974 | GO:0051726 | 0.02 | 1.52 | 41.54 | 53 | 114 | regulation of cell cycle | ADARB1, BIRC2, ARNTL, BAD, BAX, BCR, CCNE1, CCNG1, CCNG2, CDK11B, CDC25A, CDK3, CDK8, CHAD, CISH, CKS1B, CKS2, DCN, E2F2, EP300, SFN, GP1BA, HSPA8, ITGB1, JUN, JUND, CDK17, CDK14, RAD51D, RBL1, RBL2, SRSF5, SGK1, SON, STAT3, CDKL5, WEE1, NUP214, BAP1, CDKL1, CDKL2, SOCS3, UBA3, DIRAS3, CCNB2, CCNE2, SOCS6, KIAA0101, TRIB1, TACC3, USP16, COPS5, CDC37 |
1975 | GO:0008360 | 0.04 | 1.52 | 30.67 | 39 | 82 | regulation of cell shape | ANXA1, ANXA7, CSF1R, DAPK3, DIAPH1, LPAR1, EPS8, F2, PTK2B, FGD1, FGR, FYN, GAS2, ARHGAP35, HCK, HEXB, ICAM1, KDR, KIT, PALM, PTK2, PTN, RDX, S100A13, S100B, CCL24, VIL1, GAS7, TAOK2, SLC9A3R1, SEMA3E, CDC42EP2, BAIAP2, SEMA4D, CDC42EP3, PDPN, FERMT2, BVES, CORO1A |
1976 | GO:0048193 | 0.03 | 1.52 | 36.18 | 46 | 97 | Golgi vesicle transport | APP, ARL1, BBS1, BBS2, AP1S1, CLTA, DNM2, EPS15, ACSL3, FTL, BLOC1S1, GOLGA3, GOLGA4, HSPA8, KRT18, MYO1B, PRKCI, PRKD1, RAB6A, SORT1, UVRAG, BLZF1, VAMP8, AP1S2, AP1M1, AP4M1, CYTH3, TRIP11, PICK1, CLINT1, DNAJC6, SGSM2, GOLGA5, DOPEY2, AP1M2, ATP9A, ARFRP1, ATP8A1, ARFGEF2, EXOC5, KIF1C, VAMP5, RAB10, RAB31, RER1, AP4S1 |
1977 | GO:0050808 | 0.01 | 1.52 | 50.49 | 64 | 135 | synapse organization | ACHE, APP, ATP2B2, ADGRB1, ADGRB2, CACNA1A, CACNB3, CACNB4, CDC20, CDC42, CDH1, CHD4, CHRNB2, COL4A5, CTNNA2, CTNND2, EFNA5, EPHA7, EPHB1, EPHB2, EPHB3, ERBB2, ETV5, F2R, GHSR, GLRA2, GPM6A, NRG1, NRCAM, NTRK1, NTRK2, NTRK3, OXTR, PALM, PCDHGC3, RELN, PTEN, PTK2, PTN, PTPRD, RYK, SIX1, SNCB, SNCA, CNTN2, TNR, TPBG, TSC1, FZD5, CAMK1, BSN, NRXN3, NRXN1, NRXN2, CRIPT, SEMA3E, FRMPD4, SPOCK2, FARP1, CACNG2, SLC9A6, AFG3L2, RER1, IL1RAPL1 |
1978 | GO:0048609 | 0.00 | 1.52 | 130.86 | 165 | 352 | multicellular organismal reproductive process | ACVR1, ADRB2, NR0B1, ANG, ANXA1, BIRC3, ATM, ATP1A4, ATRX, AXL, BAD, BAX, BBS2, BBS4, BCL2, BCL2L1, BMP4, BRCA2, BRDT, BTG1, CAPN5, CCNB1, CCNE1, CDC25C, CFTR, CHAT, CLU, COMT, CTNNA1, CXADR, CYLC1, CYLC2, DAZ1, ACE, DIAPH2, DNM2, PHC2, ERCC1, ETS1, ETV5, FANCC, FANCD2, ACSL4, PTK2B, FANCF, FANCG, FGF7, FSHB, CENPI, FSHR, NR5A1, B4GALNT1, GAMT, GATA4, NR6A1, GDF9, B4GALT1, GHRHR, HIST1H1T, HIST1H1A, AGFG1, ICAM1, IGF1, ING2, INHA, INSL3, KDR, KISS1, KIT, KRT9, SMAD1, SMCP, KITLG, ODF1, OVOL1, P2RX1, PAFAH1B2, PAFAH1B3, SERPINA5, PDE3A, SERPINF1, PGAM2, PGM3, PPP2R1A, PRKACG, PRKAG1, PTN, PTPRN, RAD23B, RAD51C, RARA, RGS2, RPS6KB1, SBF1, SEMG1, SIAH1, SLIT3, SMARCA2, SMARCA4, SOD1, SOX3, SOX9, SP1, SPAG4, SSTR2, STAT5B, AURKA, STK11, STYX, TAC1, TAF4B, TBP, TMF1, TNP2, NR2C2, TRPM2, TSPY1, TYRO3, UBE3A, YY1, ZNF35, ZNF148, FOSL1, USP9X, USP9Y, FZD4, FKBP6, DDO, RUVBL1, TP63, PDE5A, DYNLL1, EIF2B2, EIF2B5, EIF2S2, HERC2, RNF8, RGN, FAM50A, SLIT2, QKI, PICK1, ADAMTS2, GAL3ST1, TBPL1, CLOCK, SPAG6, SPATA2, REC8, BCL2L10, BCL2L11, AKAP9, FSTL3, CRTAP, DEAF1, PRDX4, CCT6B, TOB2, ADAM28, EDDM3A, PRSS21, SOX30, HSF2BP, CIT, DDX20 |
1979 | GO:0015749 | 0.03 | 1.51 | 35.53 | 45 | 95 | monosaccharide transport | AKT2, C3, CREBL2, EDNRA, ESR1, G6PC, SLC37A4, GPC3, FFAR3, NRG1, IGF1, IL1B, INS, NUP88, NUP98, PRKAA1, PRKCI, PRKCZ, RANBP2, RPS6KB1, RTN2, SORT1, SLC2A1, SLC2A3, SLC2A4, SLC2A5, SLC5A2, STXBP3, HNF1A, TSC1, TSC2, VIL1, NUP214, AAAS, CLTCL1, PIK3R3, PEA15, NUP155, NUP93, C2CD5, SORBS1, NUP50, ARPP19, NUPL2, CAPN10 |
1980 | GO:0032434 | 0.03 | 1.51 | 35.53 | 45 | 95 | regulation of proteasomal ubiquitin-dependent protein catabolic process | ARAF, ATM, BUB1B, CCNB1, CDC20, CDC27, CENPF, CLU, CSNK1D, CSNK2A1, CSNK2A2, DAB2, DUSP1, UBE2K, DNAJB2, HSP90AB1, SMAD7, PARK2, PSEN1, PTEN, RAD23B, RB1, SDCBP, SGTA, AURKA, TTK, SUMO1, ZNF207, USP5, CUL3, CDC23, CDC16, USP14, ZW10, BAG5, RNF14, DLGAP5, KEAP1, TRIB1, ANAPC10, ARIH2, MAD2L2, GIPC1, UBE2C, GLMN |
1981 | GO:0072659 | 0.02 | 1.51 | 41.08 | 52 | 110 | protein localization to plasma membrane | AKT2, ARF6, ATP1B3, BCL2L1, BSG, CALCR, CAV3, CDH1, DAB2, DPP6, EPHA2, EMP2, FCER1G, FLOT2, FYB, GAS6, IFNG, ITGA3, ITGB1, LAMA5, P2RY1, PALM, PRKCI, PRKCZ, RAB13, RAC1, RAP2A, RDX, CLIP1, S100A10, STXBP1, TNFRSF1A, TSC2, TUB, TULP1, TULP2, TULP3, VIL1, NUMB, VAMP8, RAB11A, LIN7A, SLC9A3R1, NRXN1, TMEM59, BAG4, RAPGEF2, RAMP2, RAMP3, SORBS1, TMED2, RER1 |
1982 | GO:1901135 | 0.03 | 1.51 | 34.63 | 44 | 95 | carbohydrate derivative metabolic process | APCS, ARSA, STS, ARSD, ARSE, ARSF, BAX, CD44, CHIT1, COL11A1, G6PC, GALC, GALNS, GM2A, GPD2, GPLD1, GUSB, HEXB, HGF, HMMR, IDS, IDUA, IFNG, IHH, ITIH1, ITIH3, ITIH4, KHK, KIT, NTHL1, OGG1, OVGP1, PCSK6, PIM1, PRKCD, PSAP, RENBP, SGSH, SLC9A1, UNG, MBD4, SPOCK2, HS3ST4, SERINC3 |
1983 | GO:0019953 | 0.00 | 1.51 | 153.72 | 193 | 411 | sexual reproduction | ABAT, ACVR1, ACVR2A, ADCY3, NR0B1, ANG, ANGPT2, BIRC3, APLP2, APP, ARNTL, ATM, ATP1A4, ATRX, AVP, AXL, BAD, BAX, BBS2, BBS4, BCL2, BCL2L1, PRDM1, BMP4, BRCA2, BRDT, BTG1, CCNB1, CD9, CDC25C, CLGN, CFTR, CNR1, CTSV, CXADR, CYLC1, CYLC2, DAZ1, ACE, DIAPH2, DNM2, DRD5, EDNRA, PHC2, ERCC1, EREG, ETV5, FANCC, FANCD2, PTK2B, FANCF, FANCG, FSHB, FSHR, B4GALNT1, GAMT, GATA4, NR6A1, GDF9, B4GALT1, GLRA1, GRN, HIST1H1T, HIST1H1A, HEXB, HOXD9, HOXD10, HOXD11, HPGD, AGFG1, IGF1, IHH, IL1B, IL1R1, IL12B, ING2, INSL3, ITGB1, KIT, KRT9, LRMP, SMAD1, CD46, SMCP, ODF1, OR1D2, OVGP1, OVOL1, OXTR, P2RX1, P2RY1, P2RY2, PAFAH1B2, PAFAH1B3, SERPINA5, PDE3A, PGAM2, PGM3, PGR, PI3, PPP2R1A, PRKACG, PRKAG1, PTEN, RAD23B, RAD51C, RARA, RGS2, RPS6KB1, SBF1, SEMG1, SIAH1, SMARCA2, SMARCA4, SOD1, SOX3, SOX9, SPAG1, SPAG4, SPAM1, SPINK1, SSTR2, STAT3, AURKA, STK11, STYX, TAC1, TAF4B, TBP, NR2F2, TMF1, TNP2, NR2C2, CCT3, TRPC3, TSPY1, TYRO3, UBE3A, VIP, ZAN, EIF4H, YY1, ZNF35, ZNF148, ZP2, DNALI1, FOSL1, AAAS, NRIP1, USP9X, USP9Y, TPST2, FKBP6, DDO, RUVBL1, TP63, PDE5A, DYNLL1, EIF2S2, HERC2, RNF8, RGN, FAM50A, QKI, PICK1, ADAMTS2, ADAMTS1, GAL3ST1, TBPL1, CLOCK, SPAG6, SPATA2, REC8, BCL2L10, BCL2L11, AKAP9, FSTL3, TUBGCP3, CRTAP, DEAF1, PRDX4, CCT7, CCT4, CCT2, CCT6B, TOB2, ADAM28, EDDM3A, PRSS21, SOX30, HSF2BP, CIT, DDX20 |
1984 | GO:0061025 | 0.03 | 1.51 | 34.78 | 44 | 93 | membrane fusion | ADRB2, AKT2, ANXA1, ANXA7, BAX, BCL2A1, BNIP3, CAV2, CD9, GAS6, LRMP, OPA1, PARK2, SERPINA5, RABIF, SNAP25, SPAM1, STXBP1, SYT1, SYT4, TSG101, UVRAG, RAB7A, DYSF, EEA1, TPST2, USO1, VAMP8, STX16, STX11, STX10, SEC22C, RABEP1, SNAP29, GOSR1, SEC22B, GOSR2, C2CD5, VAV3, ATG7, YKT6, VAMP5, AFG3L2, CORO1A |
1985 | GO:0061726 | 0.01 | 1.51 | 47.50 | 60 | 127 | mitochondrion disassembly | ACTL6A, ADRB2, ANXA5, BNIP3, BNIP3L, TSPO, CDKN2A, COX8A, CSNK2A2, CTSK, EIF2S1, CTTN, STOM, FANCC, FANCF, FCGR3B, SLC37A4, GABRA5, BLOC1S1, KAT2A, HIF1A, KCNK3, KRT15, MDH1, NTHL1, P2RX5, PARK2, PEX13, SERPINB10, SFRP4, SLC1A3, SLCO1A2, SLC22A3, SNRPD1, SNRPF, SREBF1, STAT2, NR2C2, U2AF1, UBB, ZBTB17, ZNF189, FZD5, CHAF1B, RUVBL1, BECN1, ATG12, CHST3, ATG5, NUP93, ATG13, PHYHIP, IST1, TOMM20, FGFBP1, HDAC6, ATG7, HSF2BP, CDC37, ADAMTS7 |
1986 | GO:0070727 | 0.00 | 1.51 | 340.72 | 422 | 911 | cellular macromolecule localization | ABL2, ACTL6A, ADAR, AGTR2, AKT2, ANGPT1, ARCN1, ARF6, ARL1, ARL2, ARNTL, ASNA1, ATM, RERE, ATP1B3, ATR, ATRX, BAD, BARD1, BAX, BBS1, BBS2, BBS4, BCL2, BCL2L1, BCL3, BICD1, BID, BMP4, BMP6, BMPR1A, BNIP3L, BRCA1, BRCA2, BSG, BUB1B, TSPO, CACNA1A, CALCR, CAMK4, CAV3, CBLB, CCNB1, CCT6A, CD4, CD36, SCARB2, CD63, CD81, CDC42, CDH1, CDKN1A, CDKN2A, CENPA, CHRM1, AP1S1, AP2S1, CLTA, COL1A1, COPA, CSE1L, CSNK1D, CSNK2A2, CTNNA1, CTSK, CYLD, DAB2, DDX1, DHX9, DIAPH1, DKC1, DLG2, DLG3, DPP6, EDA, EGR2, EPHA2, EIF5A, EMP2, CTTN, STOM, ERBB2, ETV5, EYA1, F2R, ACSL3, FAU, FCER1G, FGF7, FLOT2, NR5A1, FYB, FYN, GAS6, KAT2A, GDI1, GFER, GNAQ, GOLGA4, SFN, GPR26, GRID2, HIST1H1B, HCLS1, NRG1, HHEX, HNMT, HES1, HSPA4, HSPA8, HSPA9, HSP90AA1, HSP90AB1, IFIT1, IFNG, IGF1, IL1B, IL10, IL12B, IL18, INS, ITGA3, ITGA4, ITGAX, ITGB1, JUN, KCNA1, KCNE1, KPNA1, KPNA2, KPNA3, KPNA4, KPNA5, TNPO1, IPO5, KRT18, LAMA5, LTBP2, SMAD3, SMAD7, NUBP1, RPL10A, TONSL, YBX1, NUP88, NUP98, OAZ1, OAZ2, OGG1, OR1D2, P2RY1, PRDX1, PALM, PARK2, PCM1, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX14, PIGR, PPM1A, PPM1B, PPP3R1, PRKCD, PRKCI, PRKCQ, PRKCZ, MAPK8, RELN, PTN, PTPN1, PEX19, PEX5, RAB6A, RAB13, RAB27A, RAC1, RAC2, RAD21, RAN, RANBP2, RANGAP1, RAP2A, RB1, RDX, RNASE2, RPGR, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, CLIP1, RTN2, RYR2, S100A10, SDCBP, SEL1L, SFRP5, STIL, SIX1, SIX3, SLC9A1, SLC11A1, SLC12A1, SUMO3, SOX9, SP100, SPAG4, SREBF1, SRP9, SRP14, SRP19, SRP68, SSR1, STAT3, STAU1, AURKA, STK11, STXBP1, STYX, CNTN2, DYNLT1, TNFAIP3, TNFRSF1A, HSP90B1, CCT3, TRIP6, TSC2, TUB, TULP1, TULP2, TULP3, U2AF1, UBE2L3, SUMO1, USP4, VIL1, WNT11, WRB, YWHAZ, ZIC1, ZBTB17, ZP2, FZD5, RAB7A, NUP214, STAM, CSRP3, AKAP1, MADCAM1, CLTCL1, UBL4A, BAP1, FZD7, DYRK2, OGT, CNTNAP1, CAMK1, AP3B1, BLZF1, PRPF18, RGS20, RUVBL1, USO1, SSNA1, AKR1C3, NUMB, DYNLL1, VAMP8, STX16, STX11, STX10, BECN1, TNFSF14, RAB11A, LIN7A, NRP1, HDAC3, AP1S2, AP1M1, HERC2, AP3D1, CDKL2, SEMA5A, RPL14, LATS1, AP4M1, ARHGEF2, RASSF9, ZW10, AURKB, ITGB1BP1, COPB2, TRIP11, TAOK2, RPL23, SLC9A3R1, ZFYVE9, NRXN1, NRXN2, PEX16, CRIPT, EIF2AK3, PICK1, AKAP6, LITAF, TMEM59, BAG4, AKAP12, NUP155, IPO13, NUP93, RAPGEF2, CROCC, RIMS2, IFT140, ZFYVE16, ATG13, SNX17, TOMM20, KEAP1, C2CD5, KIAA0753, KLHL21, SUPT7L, FAM20B, HDAC6, PDCD6, BCL2L11, PIGK, TOM1L1, TOM1, AP1M2, SAE1, ARFRP1, NUTF2, STAM2, RAMP2, RAMP3, APC2, KATNB1, ABCA7, PEMT, RAPGEF3, ARIH2, SEC24B, TACC3, SEC23B, SEC23A, CREB3, APPBP2, FBLN5, CHERP, CCT7, CCT4, CCT2, SORBS1, RBCK1, TXNIP, RRAGA, GIPC1, AHCYL1, VAMP5, SEC24A, RUVBL2, RAB10, EDAR, AFG3L2, KDELR1, AP3M2, SEC61B, TOMM34, OS9, TMED2, YWHAQ, FERMT2, KDELR2, KDELR3, IFT27, RAB35, RAB31, RER1, NUPL2, CDC37, KAT7, RPL35, SEC63 |
1987 | GO:0060562 | 0.04 | 1.51 | 31.62 | 40 | 85 | epithelial tube morphogenesis | ACVRL1, ADM, APAF1, BBS4, CSF1R, EPHA7, FZD2, GATA4, KAT2A, ARHGAP35, HIF1A, RBPJ, SMAD3, OPA1, PAX3, PFN1, PRKACB, PRKX, PSEN1, PTHLH, RALA, RARA, RYR2, SDC4, STIL, SOX11, SPINT1, ST14, TSC1, TSC2, TULP3, TWIST1, KDM6A, ZIC2, FZD6, HAND1, ZEB2, SEC24B, DEAF1, GLMN |
1988 | GO:0051049 | 0.00 | 1.50 | 65.50 | 83 | 183 | regulation of transport | ABCA2, AGTR1, ATP1A1, FXYD2, ATP4A, HCN2, CACNA1B, CACNA2D1, CACNB3, CACNB4, CASQ1, CHRNB4, CLCN3, CLCN5, CLCN6, CLCN7, CLCNKA, CLCNKB, CRY2, CYBB, DIAPH1, GDF9, GFAP, HRC, KCNA1, KCNA3, KCNA4, KCNA10, KCND2, KCND3, KCNJ1, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ12, KCNJ13, KCNJ14, KCNJ16, KCNS2, PPP1R12A, NTRK2, NUP88, NUP98, PDE4B, PDE4D, PER1, FXYD3, PTPN6, RANBP2, RBM4, RCVRN, RPS6KB1, RTN2, SCN1A, SCN2A, SCN3A, SCN7A, SCN8A, SCN10A, SCNN1B, SLC9A3, TNNC1, TNNT2, TRPC4, VDAC2, NUP214, AAAS, KCNK5, RIPK1, INPP4B, KCNAB3, KCNK6, SNCAIP, NUP155, NUP93, HCN4, CACNG2, CORIN, NUP50, NUPL2, NUDT4 |
1989 | GO:0012501 | 0.00 | 1.50 | 82.05 | 104 | 232 | programmed cell death | ADD1, ALOX15B, ANXA6, APLP1, APP, ARF6, ATP2A1, BMPR2, BRCA2, BUB1B, CASP6, CD5, CD28, TNFSF8, CD70, CDK11B, CDH1, CLC, CRH, CSE1L, CSNK2A2, CTSV, DCC, DDX5, DNASE1, DNASE2, DSP, E2F2, EPHA2, EIF5A, EP300, ERCC6, ERN1, EYA2, GAPDH, GAS2, GNB1, GNGT1, GZMH, HIC1, UBE2K, IAPP, IFI16, IFNA2, IL2RA, IL17A, IRF1, ITPR1, KPNA1, P2RX4, PAEP, PAX3, PDE1B, PPP2CB, PRKCE, PRKD1, PTPN6, PTPRH, PYGL, RAD21, RB1, DPF2, RYR2, SATB1, SCN2A, SFRP5, SHB, SIX3, SLIT3, SPN, STK11, TOP1, VIM, XPA, AIMP2, DPF1, DYRK2, CUL4A, CUL3, CUL2, CUL1, OGT, IKBKG, TNFSF9, RABEP1, BCL7C, BCL7B, LITAF, EI24, AATK, ELMO1, PDCD6IP, RNF41, ZNF443, SMNDC1, TRAIP, SEMA3A, ERN2, RRAGA, TRAF3IP2, GJB6, JTB, EDAR, IL24 |
1990 | GO:0044262 | 0.05 | 1.50 | 29.32 | 37 | 79 | cellular carbohydrate metabolic process | ACACB, EXT1, EXT2, PTK2B, GALK1, GALK2, GCGR, GLB1, GOLGA2, GOT1, GYS2, FOXA2, IDH1, IGFBP3, IGFBP5, IL15, IMPA1, INPP1, KHK, PARK2, PCK1, PDK4, PPP1R1A, PPP1R2, PTEN, RANBP2, RPE, SLC5A3, UBB, UGP2, EPM2A, SYNJ1, TMEM59, XYLB, GNE, B3GNT3, ARFGEF1 |
1991 | GO:0017148 | 0.05 | 1.49 | 31.04 | 39 | 83 | negative regulation of translation | ADAR, ANG, ATF4, CIRBP, DAPK3, EIF2S1, EIF4E, EIF4EBP1, EPRS, GAPDH, GRB7, HNRNPD, IGFBP5, ILF3, EIF3E, CAPRIN1, SMAD1, SMAD3, CNOT2, EIF2AK2, PURA, RAN, RARA, RBM4, UPF1, RPS3, SRP9, TSC1, ZFP36, EIF4EBP3, EIF2B3, EIF2B5, RQCD1, CNOT8, QKI, EIF2AK3, EIF4A3, PRG3, IGF2BP3 |
1992 | GO:0055076 | 0.05 | 1.49 | 31.04 | 39 | 83 | transition metal ion homeostasis | ABCB7, ACO1, ALAS2, XIAP, APLP2, APP, ARF1, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, ATP7B, BMP6, FTL, HIF1A, HPX, LTF, NUBP1, SLC11A2, PARK2, RHAG, S100A8, S100A9, SCO1, SLC11A1, SOD1, SLC30A2, SLC30A3, SLC30A4, PICALM, AP3D1, ATP6V0D1, ABCG2, ATP6V1G1, HEPH, ABCB6 |
1993 | GO:0045892 | 0.00 | 1.49 | 70.90 | 89 | 193 | negative regulation of transcription, DNA-templated | BIRC5, ARNTL, BCL3, BCL7A, BRCA1, RUNX2, RUNX1T1, CD38, CENPF, CREB1, DAB2, EREG, HIST1H2AE, HIST1H2AD, H2AFZ, NRG1, HMGA1, HSPA8, IFNA2, ILF3, IRF1, CITED1, PA2G4, PAX9, CHMP1A, ATP8B1, PHF2, PURA, RFX3, SET, SIX3, SMARCE1, SOX9, SOX10, TBP, TSG101, UBTF, WNT11, XRCC5, ZIC2, ZNF24, ZNF91, ZNF154, ZNF224, KDM5C, HIST1H4I, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, ZNF282, HAT1, TRIM24, HESX1, HIST1H3F, HIST1H2AG, TAF1C, TAF1B, TAF1A, UBA3, CBFA2T2, CLOCK, KDM4A, BCLAF1, NR1I3, NR1D2, ZBTB33, HDAC6, ZNF263, ZNF256, RAMP3, DEAF1, ERN2, KHDRBS1, ARID5A, YWHAQ, CCDC85B, WWP1 |
1994 | GO:0043687 | 0.00 | 1.49 | 103.23 | 129 | 276 | post-translational protein modification | BIRC5, ARCN1, AREG, ARSA, STS, ARSD, ARSE, ARSF, BGLAP, BMI1, BRCA1, CANX, CD59, CDKN2A, CGA, COPA, CSNK1D, CTSZ, DAD1, DYNC1H1, DYNC1I1, DYNC1I2, DPAGT1, PHC1, PHC2, EEF2, EIF5A, F2, F7, F10, FUT8, GALNT1, GAS6, GGCX, B4GALT1, GLB1, GMDS, GOLGA2, GOLGB1, GRIA1, HNRNPC, INS, LMAN1, MGAT2, MGAT3, NUP88, NUP98, PCNA, CFP, PGM3, PIGC, PPP6C, PRKCSH, PROC, RAB1A, RAD21, RAD52, RANBP2, RANGAP1, RPN2, TRAPPC2, SEL1L, ST6GAL1, ST8SIA1, SUMO3, SP100, UAP1, AURKA, TRAPPC10, TOP1, TOP2A, TOP2B, SUMO1, XPC, XRCC4, TUSC3, NUP214, AAAS, SMC1A, CBX4, USO1, DYNLL1, GALNT4, B4GALT4, B4GALT3, DPM2, PROZ, HERC2, SMC3, ATG12, AURKB, COPB2, B4GALT6, B4GALT5, COG1, ATG5, PIGL, GOSR1, SEC22B, GOSR2, NUP155, NUP93, GNE, PIGK, UBA2, SAE1, PREB, CHST4, B3GNT3, PIAS3, SPON1, SEC24B, COG5, SEC23A, CRTAP, ATG7, SLC35A1, YKT6, DCTN6, STAG2, NUP50, SEC24A, KDELR1, OS9, TMED2, ADAMTS13, ADAMTS5, NUPL2, ADAMTS7 |
1995 | GO:0010817 | 0.04 | 1.48 | 34.30 | 43 | 93 | regulation of hormone levels | ALDH1A1, ALDH1A3, ALDH9A1, ARNT, ATP1A1, CGA, AKR1C4, COMT, CTSZ, CYP3A4, CYP11B1, ACE, DIO2, DIO3, ESR1, FDXR, FSHB, NR5A1, IDE, PCSK6, PCSK5, RBP1, RPE65, SLC5A5, SRD5A1, STAR, STAT5B, SULT1E1, SULT1A1, TSHB, UGT2B4, UGT2B7, DDO, HSD17B6, AKR1C3, DGAT1, ALDH1A2, PCSK7, DHRS3, ATP6AP2, DHRS9, DHRS2, CORIN |
1996 | GO:0080090 | 0.00 | 1.48 | 1066.49 | 1245 | 2898 | regulation of primary metabolic process | A2M, AARS, ABAT, ABCA1, ABCA2, ABL1, ABL2, ACO1, ACTL6A, ACTN1, ACVR1, ACVR2A, ACVR2B, ACVRL1, ADAR, ADARB1, ADCY3, ADCY5, ADCY6, ADCY9, ADM, AEBP1, JAG1, AGTR2, NR0B1, AHSG, ALK, ALOX12, ALX3, AMBP, ANG, ANGPT1, ANXA3, APAF1, APCS, BIRC2, BIRC3, XIAP, BIRC5, APLP1, APLP2, APP, ARAF, AREG, PHOX2A, ARNTL, ARR3, ASCL1, ASCL2, ATF4, ATM, RERE, ATOH1, ATP6AP1, ATR, ATRX, AVPR2, BACH1, BARD1, BAX, CCND1, BCL2, BCL3, BCL7A, BDKRB2, BID, PRDM1, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, BOK, BRCA2, BRDT, ZFP36L2, BST2, KLF9, KLF5, BTF3, BTG1, BTK, BUB1B, SERPING1, C7, CALCR, CALM1, CALM3, CAMK4, CAMK2A, CASP1, CASP9, CAT, CAV2, CAV3, RUNX2, RUNX1T1, CBFB, CBL, CBLB, SERPINH1, CCK, CCNB1, CCND3, CCNE1, CCNG1, CCNH, CCNT1, CCNT2, CCT6A, CD3D, CD3E, CD4, CD28, CD80, CD86, TNFRSF8, TNFSF8, CD36, CD38, CD44, CD59, CDA, CDK11B, CDC5L, CDC20, CDC25A, CDC25C, CDC27, CDH1, CDK2, CDK4, CDK8, CDK9, CDKN1A, CDKN2A, CDX1, CDX2, CDX4, CEBPE, CENPB, CENPE, CENPF, CGA, CHAD, CHD1, CHD2, CHD3, CHD4, CHEK1, CHRNB2, CHUK, CIRBP, CISH, CKS1B, CKS2, CLU, CLK1, CLK3, CNTF, COL1A1, COL4A3, COL6A3, ATF2, CRH, CRKL, CRX, CRY1, CRY2, CRYBA1, CRYM, CSF1R, CSF2RB, CSNK1D, CSNK2A1, CSNK2A2, CSPG4, CST6, CTF1, CTGF, CTH, CTNND2, CTSH, CTSZ, CYLD, DAB2, DGKQ, DAPK3, DAZ1, DCN, ACE, GADD45A, DDIT3, DDX1, DDX5, DDX6, DFFA, DHCR24, DHFR, DIO2, DKC1, DLG2, DLG3, DLX5, DLX6, DNM2, DNMT1, DNMT3B, DPEP1, DRD5, ARID3A, RCAN1, TSC22D3, HBEGF, DUSP1, DUSP4, DUSP5, DYRK1A, E2F2, E2F4, E2F6, E4F1, EBF1, GPR183, ECM1, EDA, S1PR1, LPAR1, EDN3, EDNRA, EEF2, EFNA1, EFNA5, EGR2, EGR3, EGR4, EIF2S1, EIF2B1, EPHA2, EIF4A1, EIF4E, EIF4EBP1, EIF4G1, EIF4G2, EIF5, EIF5A, SERPINB1, ELAVL2, ELAVL1, ELK1, EMP2, EMX1, EMX2, EN1, EP300, EPHA1, EPHA5, EPHA7, EPHB1, EPRS, ERBB2, ERCC1, EREG, EYA4, ERCC3, ERCC4, ERCC6, ERF, ERG, ERN1, ESRRG, ETF1, ETS1, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA1, EYA2, EYA3, EZH1, F2, F2R, F2RL1, F3, ACSL1, FBLN1, FBN1, EFEMP1, FGA, FGF3, FGF4, FGF5, FGF7, FGG, FLI1, FLOT2, FLT3LG, FLT4, AFF2, FPR1, FRK, FSHB, FSHR, NR5A2, FYN, FZD2, GABPA, GALR1, GAPDH, GAS1, GAS6, GATA4, GATA6, NR6A1, GDF9, GFAP, GFRA2, GHRH, GHRHR, GPC3, GLP1R, GNAL, GNAQ, GNAS, GNG3, SFN, GP1BA, GPS2, GPX1, GRB2, GRB7, RAPGEF1, GRIN2A, ARHGAP35, GRM1, GRM8, GSC2, GTF2F1, GTF2I, GTF3A, BRF1, GUCA1A, GUCA1B, GUCA2A, GUCA2B, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, H2AFZ, HBE1, SERPIND1, HCK, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIP1, UBE2K, HIVEP2, ZBTB48, HLF, HLX, HMGN1, HMGCR, HMGA1, NR4A1, HMX1, HMX2, HNF4G, ONECUT1, HNRNPC, HNRNPD, HOXC10, HOXC11, HOXD3, HOXD8, HOXD9, HOXD10, HOXD11, HOXD12, HPRT1, HPX, HRC, HRG, PRMT2, HES1, HSF4, DNAJB2, HSPA8, HSPB1, HSP90AA1, HSP90AB1, ICAM1, IDE, IFI16, SP110, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGBP1, IGF1R, RBPJ, IHH, IL1A, IL2RA, IL10, IL12B, IL13, IL17A, IL18, ILF3, ILK, ING2, INHA, INSL3, EIF3E, IRAK1, IRAK2, IRF1, IRF2, IRF5, ISL1, ITGA1, ITGA3, ITGA5, ITGAV, ITGB1, ITIH1, ITIH3, ITIH4, JARID2, JUN, JUND, KCNK2, KDR, KISS1, KLKB1, KNG1, KPNA1, KPNA2, KRAS, AFF3, ABLIM1, LIMK1, LMO1, LTF, LUM, EPCAM, CAPRIN1, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MARK3, MAZ, CD46, MAP3K5, MEOX2, KITLG, MGMT, CIITA, ATXN3, MAP3K11, AFF1, FOXO4, CITED1, PPP1R12A, TONSL, CNOT2, SLC11A2, NRL, YBX1, NTF3, NTRK1, NTRK2, NTRK3, NVL, OAS3, OGG1, TNFRSF11B, SIX6, ORC1, ORC2, OTX1, OTX2, OVOL1, P2RX1, P2RY11, PA2G4, PEBP1, PCSK6, PRDX1, SERPINE1, SERPINB2, PALM, PAM, PAWR, PAX3, PAX4, PAX9, PBX1, SERPINA5, PCK1, PCNA, PCOLCE, CHMP1A, PCP4, PDE4D, PDE6G, PDE6H, PDE8A, PDE1B, ENPP2, SERPINF1, PER1, PEX14, PF4, CFP, PFDN1, ATP8B1, PFN1, PFN2, PGR, PHF2, PI3, SERPINA4, SERPINB5, SERPINB8, SERPINB9, SERPINB10, SERPINB13, SERPINI2, PIK3CB, PIM1, PRRX1, PPID, PPM1A, PPP1R1A, PPP1R2, PPP1R8, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PPP4C, PPP3R1, PPP5C, PRG2, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK8, EIF2AK2, RELN, PSEN1, PTEN, PTGIS, PTHLH, PTPN1, PTPN6, PTPRA, PTPRJ, PTPRR, PURA, PZP, RAB1A, RAC2, RAD21, RAD23B, RAD51, RAD52, RAF1, RAG1, RAN, RAP2A, RAP2B, RARA, RARB, RASA2, RBBP6, RBM4, RCVRN, RDX, RELB, RENBP, UPF1, DPF2, RFX1, RFX2, RFX3, RFXAP, RGS2, RLF, RNF6, RPA2, RPL38, RPS3, RPS4X, RPS6KA1, RPS6KB1, RPS6KB2, RREB1, RRM2, RXRA, RXRG, RYK, RYR2, S100A1, S100A7, S100A8, S100A9, S100A11, S100A12, SALL1, SATB1, SERPINB3, SERPINB4, CCL20, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SDCBP, TRAPPC2, SEMG1, SET, SETMAR, SFPQ, SFRP4, SFRP5, SRSF4, SRSF6, SRSF7, SFSWAP, SFTPD, SGK1, SGTA, SHC1, STIL, SIM2, SIX1, SIX3, SKP1, SLC9A1, SLC11A1, SLPI, SMARCA1, SMARCA2, SMARCA4, SMARCC2, SMARCD1, SMARCD3, SMARCE1, SUMO3, SNAPC1, SNAPC2, SNAPC3, SNRNP70, SOD2, SON, SOS1, SOX1, SOX2, SOX3, SOX9, SOX10, SOX11, SOX12, SP1, SP4, SP100, SPIB, SPINK1, SPINT1, SPN, SPOCK1, SRF, SRP9, SRPK2, SRY, TRIM21, SSRP1, STAT1, STAT2, STAT4, STAT6, AURKA, STK10, STYX, SUPT4H1, SUPV3L1, SUV39H1, XCL2, ADAM17, TACR3, TAF2, TAF4B, TAF5, TAF6, TAF7, TAF10, TAF13, TAL1, TAL2, CNTN2, SERPINA7, TBL1X, TBP, HNF1A, ZEB1, ZNF354A, NR2F1, NR2F2, KLF10, TMF1, TMPO, CLEC3B, TNFAIP3, TNFRSF1B, TNNI2, TOP2A, TP73, TPD52L1, NR2C1, NR2C2, HSP90B1, TRAF1, TRAF2, CCT3, TRIP6, TSC1, TSC2, TSG101, TTF1, TTK, TULP3, TNFSF4, TNFRSF4, TYMS, UBB, UBE2D2, UBE2L3, UBE2V2, UBE3A, SUMO1, UBTF, UCN, UCP1, SCGB1A1, UNG, USP4, USF1, UVRAG, VAV1, VEGFB, VEGFC, VIL1, VIP, VIPR2, VRK2, VTN, EIF4H, WFS1, WHSC1, WNT1, WNT2, WNT11, XRCC5, YY1, ZFP36, ZFP37, ZFPL1, ZIC1, ZIC2, ZNF3, ZNF711, ZNF7, ZNF8, CNBP, ZNF708, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZSCAN21, ZNF41, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF91, ZNF99, ZNF124, ZNF132, ZNF136, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF217, ZNF223, ZNF224, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, ZXDA, PRDM2, CSDE1, FZD5, BRPF1, RAB7A, AIMP2, ARHGEF5, ZNF212, BRD3, CSRP3, FOSL1, FGF23, USP5, HMGA2, CDK2AP1, ANP32A, AKAP1, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, SMC1A, USP9Y, HIST1H4I, PICALM, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, BCAR3, ZNF282, RECK, CUL4A, CUL3, CUL2, CUL1, FOXN1, KLF11, SMARCA5, ITGA8, IKBKG, IKBKAP, HAT1, GAS7, CBX4, CAMK1, PIR, BLZF1, MAPKAPK5, CDC14B, KHSRP, STK16, RGS20, RUVBL1, KLF7, CDK13, RFXANK, TP63, EIF4EBP3, CHRD, PDE5A, DYNLL1, EIF3G, EIF3J, EIF4G3, PEA15, SRSF9, CDC23, SERPINB7, TRADD, URI1, EED, RIPK1, CRADD, TNFSF14, TNFSF10, ADAM9, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10B, TNFRSF10A, TRIM24, SAP30, HESX1, NRP1, CFLAR, HDAC3, TSC22D1, PER3, CDC123, CDC16, TAX1BP1, EIF2B3, EIF2B2, EIF2B5, BUD31, CPNE1, PHOX2B, HIST1H3F, HIST1H2AG, USP13, RPS6KA4, TNFSF18, TAF1C, TAF1B, TAF1A, SOCS3, RNF8, BAZ1B, UBA3, DIRAS3, UNC119, USP14, USP2, LATS1, PDLIM1, RQCD1, SMC3, AIFM1, CCNE2, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, ZW10, SLC33A1, AURKB, VAPB, CCPG1, CRLF1, ITGB1BP1, GPR55, S1PR2, SOCS6, ZNF235, COPS2, TRIP11, HMGN3, CNOT8, TAOK2, CER1, SLIT2, SLC9A3R1, LIPG, CIAO1, RECQL5, ZRANB2, HAND1, ZNF264, QKI, FHL5, IL27RA, AKAP6, ATG5, ONECUT2, LITAF, GDF15, TBPL1, BAG5, BAG4, ZNF254, NRG2, SEC22B, GTPBP1, GABBR2, CLOCK, SOX13, RBM39, AKAP12, RNF14, TRAF4, GUCA1C, ZNF592, CTR9, ZNF516, EIF5B, KDM4A, VGLL4, BZW1, RAPGEF2, DHX34, ST18, ZNF646, SETD1A, SLK, ZFYVE16, BCLAF1, EIF4A3, ATG13, DLGAP5, MAML1, IST1, RNF40, KIAA0141, KEAP1, TSC22D2, RB1CC1, ARHGEF11, ZEB2, ZBTB24, ZNF518A, PPP1R26, SETDB1, NUAK1, SUPT7L, RNF10, ZBTB5, RBM8A, OXSR1, TNFSF15, NR1I3, RBX1, DMTF1, KCNE2, CASP8AP2, NR2E3, ACOT8, ABI1, ZBTB33, HDAC6, PDCD6, BCL2L10, BCL2L11, TOM1L1, RANBP9, RAD50, PREB, FEM1B, ZNF263, TRAP1, AKAP9, RASA4, ATP6AP2, FARP1, ZNF256, SORBS3, TNK2, RNF41, CALCRL, TRIM13, EIF1, OLIG2, PRG4, CTDSPL, TRIB1, ZNF443, SPRY1, DENND4A, SF3B4, IRX5, RAMP2, RAMP3, FSTL3, SAP18, EIF1B, APC2, APBB3, TNIP1, IKZF1, CNPY2, TRIM22, ABCA7, HMG20B, HMG20A, KLF2, CITED2, ANAPC10, PRG3, PEMT, PIAS3, IFITM3, RAPGEF3, CD2BP2, ARIH2, RBM14, ZER1, PPIE, MAD2L2, SLC30A9, TRIM38, EIF3M, CAP1, CREB3, CRTAP, STK25, CARM1, SEMA4D, ZNF211, DEAF1, ATG7, ARL6IP5, SIVA1, CCT7, CCT4, CCT2, ERN2, USP16, HEXIM1, RBCK1, ARID3B, TRIM16, TXNIP, RAD51AP1, IGF2BP3, DMRT2, KHDRBS1, CTCF, CERS1, TBR1, NRG3, STAG2, RAI1, PHTF1, GIPC1, AHCYL1, ZMYND11, ZBTB6, ZNF234, ZNF266, ZNF273, SEC24A, SPINT3, FRS3, ZNF275, RUVBL2, ARID5A, USP19, MALT1, JTB, BRD8, PAPOLA, COPS8, RNPS1, PRDX3, OS9, YWHAQ, ASCC3, COPS5, SPINK5, CCDC85B, IL24, VAX1, GTF2A1L, PIM2, ADRM1, WWP1, WWP2, SOX30, UBE2C, WDR5, PRDM7, PRDM5, CDC37, KAT7, GLMN, SOX21, PSIP1, STRAP, ZNF277, MAP4K5, SUPT16H, CHEK2, FZD10, AKAP13 |
1997 | GO:0098662 | 0.03 | 1.48 | 41.51 | 52 | 113 | inorganic cation transmembrane transport | ATP7B, CNGA1, DPP6, EDN3, HTR3A, KCNA1, KCNA2, KCNA3, KCNA4, KCNA10, KCNC1, KCNC2, KCND2, KCND3, KCNE1, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ12, KCNJ13, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN1, KCNN4, KCNQ1, KCNS2, KCNS3, REST, SLC11A1, ABCC8, SLC30A2, SLC30A3, SLC30A4, KCNAB1, KCNK5, KCNAB3, KCNK6, AKAP7, OXSR1, SLC12A6, ABCC9, AKAP9, KCNMB2, WWP2 |
1998 | GO:0044700 | 0.00 | 1.47 | 601.54 | 722 | 1791 | single organism signaling | A2M, AARS, ABCA1, ABCA4, ACADVL, ACTB, ACTG1, ACTL6A, ADD1, ADORA3, APLNR, AGXT, ANGPT2, ANXA6, BIRC5, APLP1, APLP2, APP, KLK3, TRIM23, ARL4D, ARF5, ARF6, ARHGDIB, ARL1, ARR3, ASNA1, ATF4, ATOH1, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATRX, AVPR1B, AVPR2, BAG1, ADGRB1, ADGRB2, BBS2, BBS4, BCL2A1, BCL3, TNFRSF17, OPN1SW, BCR, BNIP3L, BOK, DST, BRCA2, BSG, BTK, BUB1B, CAPN5, DAGLA, CALCR, CASP4, CASP9, CCK, KRIT1, CCNC, CCND3, CCNE1, CCNT1, CCNT2, CD3D, CD3G, CD5, CD6, CD7, CD8B, CD9, TNFRSF8, CD37, ENTPD2, CD53, CD59, CD72, CD79B, CD151, CDA, CDC5L, CDC25C, CDH1, CDH6, CDH17, CDK2, CDK4, CDK6, CDK8, CDK9, CDKN1A, CENPA, CENPE, CENPF, AKR1C4, CLCN6, TPP1, CLPS, CCR3, CCR8, ACKR2, LTB4R, CNGA1, COL4A3, COL15A1, COL16A1, CLDN3, CR2, ATF2, CREBL2, CSH1, CSNK1G3, CSNK2A2, CTLA4, CTSK, CYBB, CYP24A1, DGKA, DGKB, DGKQ, DCC, DCX, DHCR24, DIAPH1, DIAPH2, DMBT1, DOK1, RCAN1, E2F2, E2F4, S1PR3, EIF2S1, EIF4A1, EIF4E, EIF4EBP1, EIF4G1, EIF4G2, ELK1, EP300, STOM, EPHA1, EPHA7, EPHB1, EPHB2, EPHB3, ERG, ESRRG, EXT1, EXT2, EXTL3, EYA2, F2RL2, ACSL1, EFEMP1, FCER1G, FCER2, FCGR1A, FCGR1B, FCGRT, GPC4, FGD1, FLT3LG, FPR3, FRK, FSHB, CENPI, NR5A2, GAST, FUT8, FYB, GABRE, GAS1, GCGR, NR6A1, OPN1MW, GDI1, GDI2, GFRA1, GFRA2, B4GALT1, GH2, GMDS, GNA15, GNAQ, GNAT1, GNAT2, GNAZ, GNG11, GNRH2, GNRHR, GOT1, CCR10, GPR3, GPR4, XCR1, UTS2R, GPR15, GPR17, GPR19, LPAR4, GPR26, GRID1, GRN, GRM8, CXCL1, CXCL3, GRPR, GTF2I, GUCA1A, GUCY1B3, GUCY2C, GUCY2F, GUCY2D, HCK, HDGF, HIP1, HIVEP2, HLA-DQA1, NR4A1, HNF4G, HOXD3, HPGD, PRMT2, HSP90AA1, HSP90AB1, ICAM2, ICAM3, IDE, IFI16, SP110, IFIT1, IFIT3, IFNA5, IFNA13, IFNA17, IFNA21, IFNGR1, IFNW1, IGFALS, IL1R1, IL1RAP, IL10RA, IL12RB2, IL13RA2, IL15RA, IMPA1, INPP1, INPP4A, INSIG1, INSRR, IRF1, IRF2, IRF5, ISG20, ITGA4, ITGA9, ITGAD, ITGAM, ITGAX, ITGB4, CD82, KLRB1, KLRC2, KLRC3, KLRD1, KLC1, KPNA1, KPNA2, KPNA3, KPNA4, KPNA5, KRT18, KRT19, LAMA5, LIMK1, LLGL2, LTBP2, BCAM, TACSTD2, EPCAM, SMAD1, SMAD9, DNAJB9, SCGB2A1, MGAT3, CIITA, FOXO4, PPP1R12A, PPP1R12B, SEPT2, NRTN, NUP88, NUP98, OAS2, OAS3, OMG, OR1D2, OR1F1, OR2C1, OR3A2, OTX2, P2RY2, P2RY4, P2RY6, PCSK6, PRDX1, PDC, PDE3A, PDE4A, PDE4B, PDE7A, PDE8A, PDE1B, PDGFRL, PDK4, ENPP2, PENK, PF4V1, PFKFB1, CDK14, PGAM2, PIGR, PIK3C2B, PIK3C3, PIM1, PI4KA, PPP1R1A, PPP1R2, PPP2R5D, PPP4C, PRCP, PRKAG1, PRKCI, PRKCSH, PTAFR, TAS2R38, PTGDR, PTGER1, PTGER2, PTH2R, PTPN13, PTPRD, PTPRM, RAB4A, RAB5B, RAB6A, RAB13, RAB27A, RAB27B, RABIF, RAB5C, RAC2, RALA, RAN, RANBP1, RANBP2, RANGAP1, RAP1GAP, RAP1GDS1, RAP2A, RAP2B, RARB, RBL1, RBM4, RBP1, RBP2, OPN1LW, RCVRN, PRPH2, RDX, RELB, DPF2, RGR, RLN1, RIT1, RNF6, RPE65, RPS6, RPS6KB2, RPS19, RPS27, RREB1, RS1, CLIP1, RSU1, RXRA, RXRG, S100A1, SORT1, S100A6, S100A11, SAG, TSPAN31, SCTR, SDC2, SDC4, SDF2, SEL1L, SELE, SEMA3F, SGK1, STIL, SIPA1, SKP1, SP1, SP100, SPARC, SPN, SPOCK1, SRMS, SRPK2, TRIM21, TROVE2, SSR1, STAT2, STAT4, STAT5B, STAT6, STK10, STRN, STYX, SULT1A3, TACR3, TAF7, TBL1X, ZEB1, DYNLT1, NR2F1, NR2F2, TSPAN7, NR2C2, HSP90B1, TRAF1, TRHR, TRPC3, TSG101, TUFT1, TNFSF4, TYROBP, UBA7, UBE2D2, SUMO1, UPK1B, SCGB1A1, KDM6A, VAV1, VCAM1, VEGFC, VIL1, VIM, TRPV1, VRK2, LAT2, CORO2A, XPA, ZIC1, ZNF8, ZBTB17, ZNF217, ZP2, IL1R2, NUP214, AAAS, ANP32A, RND2, MADCAM1, NRIP1, CLTCL1, USP9X, SMC1A, USP9Y, HIST1H4I, FZD9, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, OR1A1, OR1D5, OR1E1, OR1E2, OR1G1, OR3A3, SPARCL1, BCAR3, NSMAF, DYRK2, CUL4A, CUL2, CUL1, SORBS2, OGT, PIK3R3, IKBKAP, COPS3, CAMK1, OR6A2, RFXANK, UNC5C, SSNA1, DCHS1, EIF4G3, S1PR4, CTNNAL1, ADAM15, TNFRSF10D, PEX11A, TRIM24, IL18RAP, INPP4B, NRP2, HCAR3, KAT2B, ALDH1A2, TAX1BP1, WASF1, HIST1H3F, RPS6KA4, TRPA1, KALRN, CDKL2, RHBDL1, BAZ1B, TAAR5, UBA3, DOK2, ANGPTL1, DIRAS3, USP8, RGN, ATP6V0D1, SMC3, AIFM1, ARHGEF1, FIBP, RASSF9, ZW10, REPS2, SLC24A1, SLC33A1, AURKB, VAPB, NUMBL, STK17B, STK17A, CYTH3, BCL7B, TAAR2, NREP, COPS2, TRIP10, GLP2R, RAB33A, RAB9A, ARHGAP29, ARHGEF6, AKAP7, IL27RA, THEMIS2, ADAMTS1, BAG3, RAB3D, ATP6V1G1, BCAR1, GTPBP1, GOSR2, CDC42BPB, RNF14, RAB36, AATK, GUCA1C, GNA14, CLCA2, FEZ2, CTR9, RALGPS1, ZNF516, SDC3, TTI1, NUP93, SEMA3E, IFT140, ARHGAP32, SLK, HDAC4, ZFYVE16, RAPGEF5, SNX17, CKAP5, MAML1, TATDN2, SPOCK2, KIAA0141, CUL7, ARHGEF11, ARHGEF17, ELMO1, GAB2, C2CD5, FARP2, TRIL, RHOBTB1, NUAK1, P2RY14, ARHGAP25, OXSR1, NR1I3, NR1D2, CASP8AP2, NR2E3, ABI1, ZBTB33, TOM1L1, GPC6, COL4A3BP, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN2, TSPAN1, ARPC2, SGK2, PREB, FEM1B, ARL4C, ARL4A, PDIA6, ARFRP1, ABI2, FARP1, WASF2, TNK2, RNF41, CALCRL, RCAN2, RAMP2, AKAP8, SIGMAR1, SEMA3A, IFITM3, PGRMC2, RBM14, CDC42EP2, IFI30, SLC9A6, CAP1, CARM1, SEMA6C, SEMA6B, SEMA4B, PRDX4, ARPC1A, ARFGEF2, IFITM2, CDC42EP3, ERLIN1, TXNIP, PDPN, RASL10A, CXCR6, TNFSF13B, EBP, RRH, CNPY3, NRG3, CHL1, NUP50, OR5I1, CCR9, PDE10A, USP20, CD300C, PROKR1, GPR83, RAB10, BRD8, SEC61B, PDIA5, FERMT2, RAB32, COPS5, KIF2C, KDELR3, IFT27, RAB35, RAB31, UPK1A, OGFR, WWP1, ADAMTS13, NUPL2, CIT, BTN3A1, PTPRT, RCAN3, CD160, ZWINT, CDC37, IL1RAPL1, CORO1A, RABL2B, RABL2A, ERLIN2, NUDT4, CHEK2, AKAP13, RASSF8, SEC63 |
1999 | GO:0015711 | 0.00 | 1.47 | 96.49 | 120 | 258 | organic anion transport | ABAT, ABCA1, ABCA2, ABCA4, ACACB, AGTR2, AGXT, AKT2, ALB, ABCD1, ANXA1, APOA1, ARG1, ATP1A2, AVP, BDKRB2, CA2, CA4, CA5A, CACNA1A, CACNB4, CCK, CD36, CFTR, AKR1C4, CPT1B, CPT2, CTNS, ACE, DRD3, FABP6, ACSL1, ACSL3, ACSL4, FOLR3, GLS, GOT2, HBA2, IL1B, KCNJ10, KCNN4, SEPT2, NTRK2, NTSR1, P2RX4, P2RX7, P2RY2, ATP8B1, PRKCD, PSEN1, ABCD3, RHAG, RXRA, SLC1A3, SLC1A6, SLC1A7, SLC2A1, SLC4A1, SLC6A6, SLC6A7, SLC6A11, SLC6A12, SLC6A13, SLC7A1, SLC7A4, SLC10A1, SLC10A2, SLC11A1, SLC16A1, SLC25A1, SLCO2A1, SLCO1A2, SLC22A5, SNAP25, SNCA, STXBP1, SYT1, TRPC4, TRPV1, SLC7A5, SLC10A3, SLC25A12, SLC4A4, SLC5A6, SLC13A2, SLC16A6, SLC16A5, SLC16A4, SLC6A5, SLC16A7, SLC33A1, SLC22A6, SLC9A3R1, SLC22A8, SLC22A13, SLC4A7, SLC4A8, ABCG1, NR1H4, ABCC5, ATP9A, SLC25A13, SLC25A15, SLC35B1, ABCC4, ABCA7, ATP8A1, SLC25A17, ARL6IP5, SLC35A1, SLCO1B1, GIPC1, CPLX1, SLC26A1, SLC22A7, SERINC3, SLC27A5, SLC27A4, SLC27A2, SLC7A9 |
2000 | GO:0006812 | 0.00 | 1.47 | 87.47 | 109 | 238 | cation transport | ABL1, ANXA5, ANXA6, ARG1, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP7B, BAX, BCL2, BMP4, TSPO, CACNA1B, CACNA2D1, CACNB3, CACNB4, CALM1, CALM3, CAMK2A, CASQ1, CD4, CHRNB4, CLCA1, CCR5, CTGF, CYBA, DDIT3, DIAPH1, F2, F2R, FTL, FYN, GAS6, GCG, GIF, GJA4, GPM6A, XCR1, FFAR1, GRIN2A, GSTM2, HRC, HTR2C, ICAM1, IGF1, ITGAV, ITPR1, ITPR2, NTSR1, P2RX3, P2RX5, PAWR, PDE4B, PDE4D, PLN, PRKD1, PTPN6, RCVRN, RYR1, RYR2, RYR3, S100A1, SCO1, CCL21, XCL1, SEMG1, SLC6A7, SLC7A1, SLC11A1, SLN, SPINK1, STC1, TPT1, TRPC1, TRPC3, TRPC4, TRPC5, UCN, TRPV1, WFS1, SLC30A2, SLC30A3, SLC30A4, TUSC3, PICALM, TRPA1, RGN, SLC6A5, SLC22A13, GSTO1, ATG5, PIEZO1, HEPH, COX17, SLC25A15, CALCRL, RAMP2, RAMP3, TRDN, CACNG2, ATP8A1, SLC30A9, SLC25A17, CREB3, CHERP, SERINC3, IL1RAPL1, CORO1A |
2001 | GO:0045936 | 0.00 | 1.47 | 103.97 | 129 | 278 | negative regulation of phosphate metabolic process | ABL1, ADAR, ADARB1, ADRA2A, AHSG, AMBP, ANGPT1, APLP1, BAX, BDKRB2, BMP4, TSPO, CALM1, CALM3, CAV3, CCNB1, CDA, CDKN1A, CDKN2A, CHAD, CISH, CRY2, CRYBA1, DCN, GADD45A, DLG2, DLG3, DRD3, DUSP1, DUSP4, DUSP5, LPAR1, EDNRA, EPHA1, F2RL1, FBLN1, GALR1, GFRA2, GNAQ, SFN, GP1BA, GPS2, RAPGEF1, GRM8, HHEX, HMGCR, FOXA2, HSPB1, IGBP1, IGF1, IGF1R, IGFBP3, IL1B, ILK, INHA, JUN, SMAD3, SMAD6, SMAD7, NTF3, NTRK3, P2RX7, PALM, PARK2, PCP4, PDE4D, PER1, PPP1R1A, PPP2R1A, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCZ, PRPSAP1, PSEN1, PTEN, PTPN1, PTPN6, PTPRJ, PTPRR, RANBP2, RB1, RGS2, SERPINB3, SNCA, SPINK1, STAT3, TAF7, NR2F2, TNFAIP3, TP73, TSC2, TWIST1, AKAP1, CUL3, OGT, DYNLL1, URI1, HDAC3, KAT2B, SOCS3, RGN, LATS1, ITGB1BP1, SOCS6, KLF4, SLIT2, SLC9A3R1, AKAP6, BAG4, GABBR2, HDAC4, PPP1R26, RANBP9, FARP1, CTDSPL, TRIB1, SPRY1, TNIP1, CD2BP2, SEMA4D, HEXIM1, ZMYND11, PRDX3, UBE2C, STRAP |
2002 | GO:0044767 | 0.00 | 1.47 | 423.71 | 516 | 1278 | single-organism developmental process | A2M, ABCA1, ACADVL, ACO1, ACTN1, ADCY6, AHSG, ALAS2, ALDH3A2, ALDOC, ALK, AMELY, AMHR2, ANXA7, APCS, ARAF, ARF1, ARHGDIB, STS, ARSE, ASTN1, BBS1, BCHE, BCL3, TNFRSF17, BLK, BMP3, BMP8B, BNIP3, BRDT, ZFP36L2, BST2, BTD, C1QC, DAGLA, CACNB3, CAMK4, CAMK2A, CAPZB, CASP6, RUNX1T1, CBLB, CBR1, CCK, CD3D, CD3E, CD4, CD8A, CD28, CD80, TNFRSF8, TNFSF8, CD36, CD72, CEBPE, CENPE, CHN1, CHRM1, CHRM3, TBCB, AP2S1, CLC, TPP1, CLPS, CLTA, ACKR2, CNN3, COL4A5, COL6A2, COL9A2, COL9A3, CLDN3, CR2, CREBL2, CRP, CSF2RB, CSNK1D, CSNK2A1, CSNK2A2, CTLA4, CYLC1, CYLC2, CYLD, CYP24A1, DAPK3, DAZ1, BRINP1, DDX1, DDX6, DHX9, DHCR24, DIAPH1, DIAPH2, DLG2, DNM1, DNASE1L2, DNASE1L3, DNASE2, DNMT3B, DPYSL3, RCAN1, EPYC, ECM2, DYRK1A, EBF1, GPR183, S1PR3, PHC1, PHC2, EFNA3, EFNA4, EIF2B1, EIF4G1, ELAVL1, ELAVL3, ELK1, EMP1, EPS8, EYA4, ERF, ETV3, ETV6, EXTL1, EYA3, F2, F2RL1, FANCA, FANCC, FBLN1, FCER1G, FGF5, FGFR4, FGG, FGR, FLG, FRK, GABRA4, GAK, GAS2, BLOC1S1, GDI1, GFRA1, GFRA2, GJB1, GLRA2, GNRH2, GNRHR, GP1BA, GRIN2A, CXCL1, HIST1H1T, HCK, HCLS1, HEXB, HIC1, HIP1, HIVEP2, HMX1, HNRNPC, AGFG1, HSPA8, HSP90AA1, HTR2C, IDH1, IFI16, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IL2RA, IL12B, IL17A, IDO1, INSL4, INSRR, IRF1, ITGA1, ITGA9, ITGAM, ITPR1, KCNJ10, KIF5A, KRT9, LUM, CAPRIN1, MAL, MAP6, MARK3, MATN3, CD46, ATXN3, ALDH6A1, DRG1, SEPT2, SLC11A2, ODF1, OMD, OGN, OMP, OPCML, P2RX5, PA2G4, PEBP1, PAEP, PRDX1, CNTN3, PCOLCE, PCP4, PDE1B, PGK1, PGM3, PHEX, PIM1, PPP2R1B, PPP2R5D, PPP5C, PRKACG, EIF2AK2, PROC, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTGDR, PTPRA, PTPRD, PTPRN, PURA, RAB1A, RAB13, RAC2, RAP2A, RASA2, RDX, RELB, RGS2, RHAG, RPL22, RPL29, RPS3A, RPS4X, RPS4Y1, RPS11, RPS19, S100A4, S100A6, S100A8, S100A9, S100A10, S100A13, SATB1, SERPINB3, SCN2A, SCN3A, SDC2, SDCBP, SDF2, SDHA, TRAPPC2, SFRP4, SRSF4, SGK1, SIAH1, ST6GAL1, SLC2A4, SLC5A3, SMARCD1, SMARCE1, SNAP25, SOS1, SOS2, SOX12, SPAG1, SPAST, SPIB, SPN, SPOCK1, SRMS, SRY, TROVE2, SULT1E1, STRN, SUPV3L1, SUV39H1, TAF4B, DYNLT1, KLF10, TMF1, CLEC3B, TNFRSF1A, TNP2, TPBG, TPD52, TRO, TRPC1, TRPC3, TRPC4, TRPC5, TSG101, TSPY1, TST, TTC3, TNFSF4, TNFRSF4, UPK1B, UCN, UCP1, SCGB1A1, UNG, NR1H2, UPK2, TRPV1, WEE1, XRCC5, ZNF3, ZNF7, ZNF16, ZNF24, ZNF45, ZNF74, RNF112, ZNF217, CSDE1, RNF103, EPM2A, FGF23, SLC7A5, DPF1, NRIP1, SMC1A, HIST1H4I, FZD9, GFI1B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, TAGLN2, SOAT2, DOC2A, FKBP6, CNTNAP1, GAS7, PIR, AP3B1, CDC14A, KLF7, CDK13, PTCH2, AKR1C3, PDE5A, BECN1, PEA15, JRKL, TNK1, TRADD, EDF1, EED, RIPK1, TNFSF9, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, PEX11A, INPP4B, KAT2B, ARHGEF7, VNN2, EIF2B3, BSN, WASF1, RPS6KA4, TNFSF18, KALRN, RNF8, PAPSS1, CLDN1, KRT75, SMC3, AIFM1, ARHGEF1, CBFA2T2, EXO1, ARHGEF2, DDX21, ZMYM6, PDLIM7, BCL7B, GPR55, S1PR2, SNAP29, TAOK2, NRXN2, RECQL4, IL27RA, PSMF1, ADAMTS4, GAL3ST1, TBPL1, BAG5, NRG2, MINPP1, SPAG6, SOX13, TRAF4, ABCG1, FEZ2, ZNF516, RAPGEF5, SPOCK2, SPATA2, ARHGEF11, ZBTB24, GAB2, KIAA0319, PSMD6, FIG4, RNF10, NR1I3, RBX1, DOPEY2, HDAC6, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, ARL4A, AKAP9, RASA4, FARP1, DHRS9, ZNF256, TNK2, RNF41, PSME3, DHRS2, PSMD14, PRG4, TRIB1, ABCC4, SIGMAR1, KATNB1, HMG20A, SPON2, CDC42EP2, FAM3C, GPNMB, BAIAP2, MAD2L2, CAP1, STK25, CHERP, PRDX4, ARPC1A, OLFM4, ARFGEF1, DPYSL4, CDC42EP3, TRIM16, TXNIP, GAS2L1, AVIL, EBP, FUT9, STAG2, CHL1, TOB2, SEPT9, CPLX2, FRS3, ARID5A, MALT1, FERMT2, SLC27A4, CCDC85B, RAB35, UPK1A, WWP1, STMN2, CIT, KIF3A, IL1RAPL1, CORO1A, SOX21, STRAP, ADAMTS7, FZD10, DDX20 |
2003 | GO:1903047 | 0.00 | 1.47 | 169.96 | 210 | 457 | mitotic cell cycle process | ABL1, ACVR1, ANXA1, BIRC5, APP, ATRX, BBS4, BCAT1, CCND1, BCL2, BCL2L1, BID, BMP4, BUB1B, CAMK2A, CAV2, CCNB1, CCNF, CCNG1, CCNG2, CCNH, CD28, CDK11B, CDC20, CDC25A, CDC25C, CDC27, CDC42, CDK3, CDK4, CDK6, CDKN2A, CENPA, CENPE, CENPF, CETN1, CHEK1, CKS1B, ATF2, CSNK1D, CSNK2A1, CSNK2A2, DAPK3, GADD45A, DYNC1H1, DYNC1I2, DNM2, DRD3, DUSP1, E4F1, EDN3, EIF4E, EIF4EBP1, EML1, EP300, EPS8, EREG, ERCC3, EYA1, FGFR3, GOLGA2, HGF, PRMT2, HSP90AA1, IGF1, IGF1R, IGF2, IL1A, IL1B, INS, ITGB1, KIF25, FOXO4, PPP1R12A, PPP1R12B, SEPT2, NUMA1, NUP88, NUP98, ORC2, ORC4, ORC5, PBX1, PCM1, CHMP1A, CDK14, PIM1, PPP2R1A, PPP2R2A, PPP5C, PPP6C, PRCC, PRIM2, PRKAR2B, PRKCQ, PTEN, PTPN6, RAD21, RAD51C, RAD51B, RAN, RANBP2, RDX, RPA2, RPA3, RPL24, RPS3, RPS6KB1, CLIP1, SETMAR, STIL, SKP1, SMARCA4, SMARCD3, AURKA, ADAM17, TAF2, DYNLT3, DYNLT1, TOP2A, TOP2B, TP73, TPD52L1, TTK, TUBA4A, TUBG1, UBE2E2, VRK1, WEE1, XPC, ZNF207, ALMS1, TUBA1A, NUP214, AAAS, HMGA2, CLTCL1, USP9X, SMC1A, CUL4A, CUL3, CUL2, CUL1, PPM1D, DGKZ, CDC14A, RUVBL1, CDK13, TP63, SSNA1, DYNLL1, BECN1, CDC23, RAB11A, BANF1, CDC16, PHOX2B, RNF8, USP8, LATS1, SMC3, CCNB2, CCNE2, CTDP1, ARHGEF2, ZW10, AURKB, KIF3B, RECQL5, MAD2L1BP, NUP155, CEP135, NUP93, DLGAP5, CKAP5, CUL7, GINS1, KLHL21, DCLRE1A, TOM1L1, SMC4, KIF20A, AKAP9, CTDSPL, SPRY1, AKAP8, KATNB1, ANAPC10, TUBGCP3, MAD2L2, SSSCA1, USP16, STAMBP, PDPN, KHDRBS1, DCTN6, STAG2, NUP50, ARPP19, TUBGCP2, JTB, TXNL4A, DBF4, KIF2C, PIM2, PAPD7, UBE2C, NUPL2, CIT, ZWINT |
2004 | GO:1902532 | 0.01 | 1.46 | 64.40 | 80 | 173 | negative regulation of intracellular signal transduction | ABL2, AMBP, BCL2, BCL2L1, BDKRB2, BMP4, CALM1, CALM3, CASQ2, CAV3, CD44, CHAD, CISH, CLU, DCN, DUSP1, DUSP4, DUSP5, DYRK1A, F2RL1, FBLN1, GCG, GP1BA, GPS2, GPX1, GRINA, ARHGAP35, GSTM2, HMGCR, HSPB1, IGBP1, IGF1, IL1B, ING2, INS, ITGA3, ITGB1, ITPR1, OPA1, P2RX7, PARK2, PDE3B, PPP2CB, PPP2R1A, PRKCD, PTPN1, PTPN6, PTPRR, RASA2, RGS2, SERPINB3, SEC14L1, SNAI1, SOD2, SPINK1, TP73, TPT1, VDAC2, WFS1, CUL3, DGKZ, TNK1, URI1, HDAC3, CPNE1, SOCS3, ARHGEF2, ITGB1BP1, SOCS6, SLIT2, GSTO1, BAG5, BCL2L10, RANBP9, TRAP1, RASA4, SPRY1, TRDN, CREB3, IVNS1ABP |
2005 | GO:0007154 | 0.00 | 1.45 | 512.69 | 616 | 1542 | cell communication | AARS, ABCA4, ACADVL, ACTB, ACTG1, ADD1, ADORA3, APLNR, AGXT, ANG, ANGPT2, ANXA6, APLP1, KLK3, TRIM23, ARL4D, ARF5, ARL1, ARR3, ASNA1, ATOH1, ATP2A1, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATRX, AVPR1B, AVPR2, BAG1, ADGRB1, ADGRB2, BBS2, BBS4, BCL2A1, TNFRSF17, OPN1SW, BOK, DST, BRCA2, BSG, BTK, BUB1B, CAPN5, DAGLA, CALCR, CASP4, CASP9, CASQ1, CCK, KRIT1, CCNC, CCND3, CCNT1, CCNT2, CD3D, CD3G, CD5, CD6, CD7, CD8B, CD9, TNFRSF8, CD37, ENTPD2, CD53, CD59, CD72, CD79B, CD151, CDA, CDC5L, CDC25C, CDH1, CDH6, CDH17, CDK2, CDK4, CDK6, CDK8, CDK9, CENPA, CENPE, CENPF, AKR1C4, CLCN6, TPP1, CLPS, CCR3, CCR8, ACKR2, LTB4R, COL4A3, COL15A1, COL16A1, CLDN3, CR2, ATF2, CREBL2, CSH1, CSNK1G3, CTLA4, CYBB, DGKA, DGKB, DGKQ, DCC, DCX, DHCR24, DIAPH1, DIAPH2, DMBT1, DOK1, DPP6, E2F2, E2F4, S1PR1, S1PR3, EIF4A1, EIF4E, EIF4EBP1, EIF4G1, EIF4G2, ELK1, EPHA1, EPHB2, EPHB3, ERG, ESRRG, EXT1, EXT2, EXTL3, EYA2, F2RL2, ACSL1, EFEMP1, FCER1G, FCER2, FCGR1A, FCGR1B, FCGRT, GPC4, FLT3LG, FPR3, FRK, FSHB, CENPI, NR5A2, GAST, FUT8, FYB, GABRE, GCGR, NR6A1, OPN1MW, GFRA1, B4GALT1, GH2, GJB5, GMDS, GNA15, GNAQ, GNAT2, GNAZ, GNG11, GNRH2, GNRHR, GOT1, CCR10, GPR3, GPR4, XCR1, UTS2R, GPR15, GPR17, GPR19, LPAR4, GPR26, GRID1, GRN, GRM8, CXCL1, CXCL3, GRPR, GTF2I, GUCY1B3, GUCY2C, HCK, HDGF, HIP1, HIVEP2, HLA-DQA1, NR4A1, HNF4G, HOXD3, HPGD, HSP90AA1, ICAM2, ICAM3, IDE, SP110, IFIT1, IFIT3, IGFALS, IL1R1, IL1RAP, IL10RA, IL12RB2, IL13RA2, IL15RA, IMPA1, INPP1, INPP4A, INSIG1, INSRR, IRF2, IRF5, ISG20, ITGA4, ITGA9, ITGAD, ITGAM, ITGAX, ITGB4, CD82, KLRB1, KLRC2, KLRC3, KLRD1, KLC1, KPNA1, KPNA2, KPNA3, KPNA4, KPNA5, KRT18, KRT19, LAMA5, LIMK1, LTBP2, BCAM, TACSTD2, EPCAM, SMAD1, SMAD9, DNAJB9, SCGB2A1, MGAT3, CIITA, FOXO4, PPP1R12A, PPP1R12B, SEPT2, NRCAM, NRTN, NUP88, NUP98, OAS2, OAS3, OMG, OR1D2, OR1F1, OR2C1, OR3A2, P2RY2, P2RY4, P2RY6, PDC, PDE3A, PDE4B, PDE7A, PDE8A, PDE1B, PDGFRL, ENPP2, PF4V1, PFKFB1, PGAM2, PIGR, PIK3C2B, PI4KA, PPP1R1A, PPP2R5D, PPP4C, PRKAG1, PRKCI, PRKCSH, PTAFR, TAS2R38, PTGDR, PTGER1, PTGER2, PTH2R, PTPRD, PTPRM, RAB4A, RAB5B, RAB6A, RAB13, RAB27A, RAB27B, RABIF, RAB5C, RALA, RAN, RANBP1, RANBP2, RANGAP1, RAP1GDS1, RAP2B, RARB, RBL1, RBM4, RBP1, RBP2, OPN1LW, PRPH2, RELB, DPF2, RGR, RLN1, RIT1, RPE65, RPS6, RPS6KB2, RPS19, RPS27, RREB1, CLIP1, RSU1, RXRA, RXRG, RYR1, RYR3, S100A1, SORT1, S100A6, S100A11, TSPAN31, SCN1A, SCN2A, SCN3A, SCN7A, SCN8A, SCTR, SDC2, SDC4, SEL1L, SELE, SEMA3F, SGK1, STIL, SKP1, SP1, SPARC, SPN, SPOCK1, SRMS, SRPK2, TRIM21, TROVE2, SSR1, STAT4, STAT5B, STAT6, STK10, STRN, SULT1A3, TACR3, TAF7, TBL1X, NR2F1, NR2F2, TSPAN7, NR2C2, HSP90B1, TRHR, TRPC3, TUFT1, TNFSF4, TYROBP, UBA7, UBE2D2, UPK1B, SCGB1A1, KDM6A, VCAM1, VIL1, VIM, TRPV1, LAT2, CORO2A, XPA, ZNF8, ZNF217, ZP2, IL1R2, NUP214, AAAS, ANP32A, RND2, MADCAM1, NRIP1, CLTCL1, USP9X, SMC1A, USP9Y, HIST1H4I, FZD9, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, OR1A1, OR1D5, OR1E1, OR1E2, OR1G1, OR3A3, SPARCL1, BCAR3, NSMAF, DYRK2, CUL4A, CUL2, CUL1, SORBS2, PIK3R3, IKBKAP, COPS3, CAMK1, OR6A2, RFXANK, UNC5C, SSNA1, DCHS1, EIF4G3, S1PR4, CTNNAL1, ADAM15, TNFRSF10D, PEX11A, IL18RAP, NRP2, HCAR3, KAT2B, ALDH1A2, WASF1, HIST1H3F, RPS6KA4, TRPA1, CDKL2, RHBDL1, TAAR5, UBA3, DOK2, ANGPTL1, DIRAS3, USP8, ATP6V0D1, SMC3, FIBP, RASSF9, ZW10, REPS2, SLC24A1, SLC33A1, AURKB, VAPB, NUMBL, STK17B, STK17A, BCL7B, TAAR2, COPS2, GLP2R, RAB9A, AKAP7, IL27RA, THEMIS2, BAG3, RAB3D, ATP6V1G1, BCAR1, GTPBP1, GOSR2, CDC42BPB, RAB36, AATK, GNA14, CLCA2, CTR9, ZNF516, SDC3, NUP93, SEMA3E, SLK, HDAC4, ZFYVE16, RAPGEF5, SNX17, CKAP5, MAML1, TATDN2, SPOCK2, KIAA0141, CUL7, ELMO1, GAB2, C2CD5, TRIL, NUAK1, P2RY14, OXSR1, NR1I3, NR1D2, CASP8AP2, NR2E3, ABI1, ZBTB33, TOM1L1, GPC6, COL4A3BP, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN2, TSPAN1, ARPC2, SGK2, PREB, ARL4C, ARL4A, PDIA6, ARFRP1, ABI2, WASF2, TNK2, CALCRL, AKAP8, SIGMAR1, SEMA3A, IFITM3, PGRMC2, RBM14, CDC42EP2, IFI30, CAP1, SEMA6C, SEMA6B, SEMA4B, PRDX4, ARPC1A, IFITM2, CDC42EP3, ERLIN1, TXNIP, PDPN, RASL10A, CXCR6, TNFSF13B, EBP, RRH, CNPY3, NRG3, CHL1, NUP50, AHCYL1, OR5I1, CCR9, GJB6, CD300C, PROKR1, GPR83, RAB10, BRD8, SEC61B, PDIA5, FERMT2, RAB32, KIF2C, KDELR3, IFT27, RAB35, RAB31, UPK1A, OGFR, WWP1, ADAMTS13, NUPL2, CIT, BTN3A1, PTPRT, CD160, ZWINT, IL1RAPL1, CORO1A, RABL2B, RABL2A, ERLIN2, NUDT4, CHEK2, RASSF8, SEC63 |
2006 | GO:0055085 | 0.00 | 1.45 | 86.27 | 107 | 237 | transmembrane transport | ABCA2, ABCA3, ABCB7, ABCA4, ADCY3, ADCY5, ADCY6, ADCY9, ADD1, ALB, ABCD1, APOA1, AVP, AVPR2, AZGP1, BCL2, BCL2A1, CA2, CDH17, CTNS, EIF2S1, EIF2S3, FTL, G6PC, SLC37A4, GJA3, GJB1, GNAS, HSPA4, HSPA8, HSP90AA1, INS, MAL, NUP88, NUP98, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX14, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PEX19, ABCD3, ABCD4, PEX5, RANBP2, ABCE1, RTN2, SLC2A1, SLC2A3, SLC2A4, SLC5A2, SLC5A3, SLC6A11, SLC6A12, SLC6A13, SLC10A1, SLC10A2, SLC15A1, SLC15A2, SLC25A1, SLCO2A1, SLCO1A2, TUSC3, NUP214, SLC25A16, AAAS, SLC14A2, SLC10A3, RAB11A, EIF2S2, SLC13A2, SLC6A5, SLC28A1, SLC33A1, SLC22A13, PEX16, ABCG1, NUP155, NUP93, TOMM20, HEPH, C2CD5, SV2B, ABCC5, ABCB6, ABCC4, ABCA7, ABCA10, ABCA9, ABCA8, SLC35A1, SLCO1B1, NUP50, SLC22A7, AFG3L2, SLC27A4, SLC35D2, NUPL2, ABCB8 |
2007 | GO:0006888 | 0.03 | 1.45 | 41.14 | 51 | 110 | ER to Golgi vesicle-mediated transport | ARCN1, AREG, ARF1, BGLAP, CD59, COPA, CSNK1D, CTSZ, DYNC1H1, DYNC1I1, DYNC1I2, F2, F7, F10, GAS1, GAS6, GOLGA2, GOLGB1, GRIA1, INS, INSIG1, LMAN1, PPP6C, PROC, RAB1A, TRAPPC2, SPAST, TRAPPC10, CUL3, USO1, DYNLL1, PROZ, SEC22C, ZW10, VAPB, COPB2, COG1, GOSR1, SEC22B, GOSR2, PREB, SEC24B, COG5, SEC23B, SEC23A, YKT6, DCTN6, SEC24A, KDELR1, TMED2, RAB35 |
2008 | GO:0034765 | 0.02 | 1.45 | 54.86 | 68 | 148 | regulation of ion transmembrane transport | ADRA2A, ATP1A2, FXYD2, HCN2, CACNA1A, CACNA1B, CACNA2D1, CACNB3, CACNB4, CASQ1, CRHBP, CYBA, CYBB, DIAPH1, DRD3, STOM, PTK2B, HRC, KCNA1, KCNA2, KCNA3, KCNA4, KCNA10, KCND2, KCND3, KCNJ1, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ12, KCNJ13, KCNJ14, KCNJ16, KCNS2, KCNS3, PAWR, PDE4B, PDE4D, FXYD3, PLN, PRKCE, PRKD1, PTPN6, SCN1A, SCN2A, SCN3A, SCN7A, SCN8A, SCN10A, SEMG1, SLN, SPINK1, KCNAB1, KCNK5, KCNAB3, SLC9A3R1, NRXN1, KCNK6, ATG5, OXSR1, HCN4, CACNG2, AHCYL1, YWHAQ, WWP2, CORO1A |
2009 | GO:0016050 | 0.02 | 1.45 | 48.53 | 60 | 130 | vesicle organization | ABCA1, ARCN1, AREG, ARF1, BCL2, CD59, AP2S1, CLCN3, COPA, CREB1, CSNK1D, CTSZ, EPS15, F2R, BLOC1S1, GOLGA2, GRIA1, HIP1, AGFG1, INSIG1, LMAN1, P2RX7, CHMP1A, PPP6C, PRKCI, PTPRN, RAB1A, SORT1, S100A10, SDC4, SDCBP, TRAPPC2, SYP, TRAPPC10, TMF1, TSG101, TYRP1, STAM, PICALM, SRPX, CUL3, AP3B1, CADPS, AP1M1, AP3D1, VAPB, COPB2, TBPL1, GOSR2, ZFYVE16, ZEB2, SNAP91, PDCD6IP, PREB, ATP8A1, SEC24B, SEC23A, SEC24A, TMED2, RAB32 |
2010 | GO:0036211 | 0.00 | 1.43 | 819.83 | 963 | 2192 | protein modification process | ABCA1, ABL1, ABL2, ABO, ACP1, ACTL6A, ACVR1, ACVR2A, ACVR2B, ACVRL1, ADAM10, ADAR, ADARB1, ADCY3, ADCY5, ADCY6, ADCY9, ADH5, PARP4, ADRA1B, ADRA2A, ADRB2, AGA, AGTR2, AKT2, ALK, AMBP, AMHR2, ANG, ANGPT1, ANXA1, BIRC2, BIRC3, XIAP, BIRC5, APLP2, APOA1, APP, ARAF, ARCN1, TRIM23, AREG, ARNT, ARR3, ARSA, STS, ARSD, ARSE, ARSF, ART1, ART3, ASL, ATM, ATP6AP1, ATR, AVP, AVPR2, AXL, BACH1, BARD1, BAX, CCND1, BCL2, OPN1SW, BCR, BDKRB2, BGLAP, BHMT, BLK, BMI1, BMP1, BMP3, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, BRCA1, BRCA2, BTG1, BTK, BUB1B, TSPO, C3, CALM1, CALM3, CAMK4, CAMK2A, CANX, CAV2, CAV3, CBFB, CBL, CBLB, CCK, CCNB1, CCNC, CCND3, CCNE1, CCNF, CCNG1, CCNH, CCNT1, CCNT2, CD3E, CD4, CD80, CD36, CD44, CD59, CD81, CDK11B, CDC20, CDC25A, CDC25C, CDC27, CDC42, CDK2, CDK3, CDK4, CDK6, CDK8, CDK9, CDKN1A, CDKN2A, CENPE, CENPF, CGA, CHAD, CHEK1, CHRM1, CHRM3, CHUK, CISH, CKS1B, CKS2, CLU, CLK1, CLK3, CCR5, CNTF, COL3A1, COPA, CREB1, ATF2, CREBL2, CRH, CRKL, CRY1, CRY2, CRYBA1, CSF1R, CSF2RB, CSNK1D, CSNK1G2, CSNK1G3, CSNK2A1, CSNK2A2, CSPG4, CTF1, CTGF, CTH, CTSH, CTSZ, CYLD, DAB2, DAD1, DAPK3, DCN, ACE, DCX, DDB2, GADD45A, DLG2, DLG3, DYNC1H1, DYNC1I1, DYNC1I2, DNMT1, DNMT3B, DPAGT1, DSP, HBEGF, DUSP1, DUSP4, DUSP5, DYRK1A, E4F1, GPR183, LPAR1, EDN3, EDNRA, PHC1, PHC2, EEF2, EFNA1, EFNA5, EGR2, EIF2S1, EPHA2, EIF5A, ELK1, EMP2, EP300, EPHA1, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, ERBB2, EREG, EYA4, ERCC3, ERCC6, ERG, ERN1, ESR1, ETF1, EVPL, EXT1, EXT2, EXTL1, EYA1, EYA2, EYA3, EZH1, F2, F2R, F2RL1, F7, F10, ACSL1, PTK2B, FANCF, FBLN1, EFEMP1, FGA, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, FGG, FGR, FKBP3, FKBP5, FLT1, FLT3, FLT3LG, FLT4, FPR1, FRK, FSHR, FUT6, FUT8, FYB, FYN, GAD1, GAK, B4GALNT1, GALNT1, GAPDH, GAS6, GCG, BLOC1S1, KAT2A, OPN1MW, GDF9, GFI1, GFRA2, GGCX, B4GALT1, GLB1, GMDS, GNAQ, GNG3, GOLGA2, GOLGB1, SFN, GP1BA, GPLD1, GRK6, GPS2, GPX1, GRB2, RAPGEF1, GRIA1, GRIN2A, GRM1, GUCY2C, GUCY2F, GUCY2D, HIST1H1B, HCK, HCLS1, HGF, NRG1, HHEX, UBE2K, HLCS, HMBS, HMGCR, HNRNPC, HPX, HRC, HRG, PRMT2, HES1, HSF4, DNAJB2, HSPB1, HSP90AA1, HSP90AB1, HTR2C, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGBP1, IGF1, IGF1R, IGF2, IGFBP3, IL1A, IL1B, IL2RA, IL12B, IL12RB2, IL13, IL15, IL18, ILF3, ILK, INHA, INS, INSRR, IRAK1, IRAK2, ISL1, ITGA1, ITGA5, ITGAV, ITGB1, JARID2, JUN, KCNE1, KCNH2, KDR, KISS1, KIT, KRAS, LIMK1, LIPE, LMAN1, LTF, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAN2B1, MARK3, MDH2, MAP3K5, MGAT2, MGAT3, KITLG, ATXN3, MAP3K11, PPP1R12A, CNOT4, NRTN, NTF3, NTRK1, NTRK2, NTRK3, NUP88, NUP98, OAS2, TNFRSF11B, OXTR, P2RX7, P2RY1, P4HA1, PEBP1, PRDX1, PAH, PAM, PARK2, PAWR, PCK1, PCNA, PCP4, CDK17, PDE4D, PDE6G, PDE6H, PDK4, ENPP2, PER1, PEX12, CFP, PFN2, CDK14, PGGT1B, PGM3, PHEX, PHF2, PHKA1, PHKA2, PHKB, PHKG1, PIGC, PIK3C3, PIK3CB, PIM1, PPIB, PPID, PPM1A, PPM1B, PPP1R1A, PPP1R2, PPP2CB, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PPP4C, PPP3R1, PPP5C, PPP6C, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PRKCE, PRKCI, PRKD1, PRKCQ, PRKCSH, PRKCZ, MAPK8, EIF2AK2, PRKX, PROC, RELN, PSAP, PSEN1, PSKH1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTGER4, PTK2, PTPN1, PTPN4, PTPN6, PTPN7, PTPN13, PTPRA, PTPRD, PTPRE, PTPRH, PTPRJ, PTPRM, PTPRN, PTPRN2, PTPRR, PTPRS, RAB1A, RAB3B, RAB6A, RABGGTA, RABGGTB, RAC1, RAC2, RAD21, RAD51, RAD52, RAF1, RAG1, RAG2, RANBP2, RANGAP1, RAP2A, RAP2B, RARA, RASA2, RB1, RBBP6, RBM4, OPN1LW, REST, RGR, RGS2, RNF6, RPN2, RPS3, RPS6KA1, RPS6KB1, RPS6KB2, RYK, S100A7, S100A8, S100A9, S100A12, SALL1, SATB1, SBF1, SERPINB3, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SDCBP, SDF2, TRAPPC2, SEL1L, SET, SETMAR, SFPQ, SGK1, SHC1, SHMT2, SIAH1, ST6GAL1, ST8SIA1, STIL, SKP1, SLC11A1, SUMO3, SNCA, SOD1, SOS1, SOX2, SOX9, SP100, UAP1, SPINK1, SPN, SPRR1B, SPRR2A, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3, SREBF1, SRMS, SRPK2, TRIM21, STAT4, AURKA, CDKL5, STK10, STK11, STYX, SUV39H1, XCL2, ADAM17, TAF5, TAF7, TAF10, TBL1X, NR2F2, TRAPPC10, TNFAIP3, TNFRSF1A, TNFRSF1B, TOP1, TOP2A, TOP2B, TP73, TPD52L1, NR2C2, HSP90B1, TRAF2, TSC1, TSC2, TSG101, TTC3, TTK, TWIST1, TNFRSF4, TYRO3, UBB, UBA7, UBE2D2, UBE2E2, UBE2H, UBE2L3, UBE2V2, UBE3A, SUMO1, UCN, USP4, KDM6A, UTY, UVRAG, VEGFB, VEGFC, VRK1, VRK2, VTN, WEE1, WFS1, WHSC1, WNT1, WNT11, XPC, XRCC4, TRIM25, ZNF207, PRDM2, RNF103, FZD5, SCG2, BRPF1, EPM2A, AIMP2, ARHGEF5, TUSC3, NUP214, FGF23, USP5, AAAS, HMGA2, CDK2AP1, GAN, AKAP1, USP11, USP9X, KDM5C, SMC1A, UBL4A, USP9Y, HIST1H4I, BAP1, FZD4, FZD7, FZD8, GFI1B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, BCAR3, DYRK2, CUL4A, CUL3, CUL2, CUL1, TPST2, TPST1, FKBP6, OGT, PPM1D, IKBKG, IKBKAP, HAT1, COPS3, CBX4, CAMK1, MAPKAPK5, CDC14B, CDC14A, STK16, RUVBL1, USO1, CDK13, PDE5A, DYNLL1, PEA15, GALNT4, CDC23, B4GALT4, B4GALT3, B3GALT2, TNK1, URI1, EED, RNGTT, RIPK1, ADAM9, RIPK2, TNFRSF6B, RIOK3, TNFRSF18, TNFRSF10B, TNFRSF10A, DYRK4, TRIM24, CDKL1, DPM2, NRP1, HDAC3, KAT2B, PROZ, CDC16, HERC2, P4HA2, USP13, RPS6KA4, TNFSF18, KALRN, CDKL2, SOCS3, RNF8, BAZ1B, UBA3, DIRAS3, UNC119, USP14, USP2, USP8, RGN, LATS1, SMC3, CCNE2, ATG12, DYRK1B, CTDP1, ARHGEF2, ZW10, AURKB, VAPB, CRLF1, STK17B, STK17A, ITGB1BP1, COPB2, GPR55, S1PR2, SOCS6, KLF4, COPS2, GTF3C4, B4GALT6, B4GALT5, TAOK2, SLIT2, UBE4A, SLC9A3R1, COG1, EIF2AK3, ARHGEF6, PICK1, AKAP6, ATG5, PIGL, PSMF1, GAL3ST1, GDF15, GOSR1, TMEM59, BAG5, BAG4, NRG2, RAB3D, SEC22B, GOSR2, CLOCK, CDC42BPB, RNF14, RNF7, TRAF4, AATK, NUP155, CTR9, TTLL4, KDM4A, NUP93, UBE3C, RAPGEF2, SETD1A, SLK, HDAC4, ATG13, DLGAP5, MAML1, SPOCK2, RNF40, KEAP1, CUL7, RB1CC1, DNAJC6, ZEB2, PPP1R26, PSMD6, SETDB1, NUAK1, KLHL21, SUPT7L, RNF10, OXSR1, USP3, TNFSF15, NR1H4, RBX1, ABI1, HDAC6, GNE, PIGK, TOM1L1, SH2D3C, SH2D3A, RANBP9, UBA2, SAE1, COL4A3BP, SGK2, RAD50, PREB, FEM1B, AKAP9, ABI2, RASA4, ATP6AP2, FARP1, CHST4, SORBS3, TNK2, RNF41, PSME3, TRIM13, PSMD14, CTDSPL, TRIB1, SPRY1, CWC27, SPEG, TRAIP, BCKDK, MARCH6, TNIP1, TMEM5, B3GNT3, TRIM22, ABCA7, HMG20B, ANAPC10, PIAS3, RAPGEF3, SPON1, CD2BP2, UBAC1, ARIH2, SEC24B, RBM14, ZER1, PPIE, MAD2L2, PPIH, COG5, TRIM38, UBE2E3, SEC23A, CRTAP, STK25, CARM1, SEMA4D, ATG7, PRDX4, ARL6IP5, SLC35A1, ARFGEF1, ERN2, USP16, HEXIM1, RBCK1, STAMBP, TRIM16, YKT6, CTCF, DCTN6, FUT9, RRH, USP39, NRG3, STAG2, NUP50, ZMYND11, ARPP19, SEC24A, FRS3, RUVBL2, ARID5A, USP20, USP19, MALT1, JTB, BRD8, COPS8, PRDX3, KDELR1, OS9, TMED2, COPS6, COPS5, IL24, PIM2, WWP1, WWP2, UBE2C, WDR5, ADAMTS13, ADAMTS5, NUPL2, PTPN21, ATE1, PRDM7, PRDM5, CIT, PTPRT, CDC37, KAT7, GLMN, FICD, STRAP, ADAMTS7, MAP4K5, CHEK2, FZD10, AKAP13 |
2011 | GO:0034248 | 0.01 | 1.43 | 81.53 | 100 | 218 | regulation of cellular amide metabolic process | AARS, ACO1, ADAR, AKT2, ANG, APP, ATF4, BCL3, CD28, CDK4, CIRBP, CLU, DAPK3, DAZ1, DDX1, DDX6, DIO2, EEF2, EIF2S1, EIF2B1, EIF4A1, EIF4E, EIF4EBP1, EIF4G1, EIF4G2, EIF5, EIF5A, ELAVL1, EPRS, ERBB2, ETF1, PTK2B, GAPDH, GRB7, HNRNPD, HSPB1, IGF1, IGFBP5, ILF3, EIF3E, CAPRIN1, SMAD1, SMAD3, CNOT2, PA2G4, PER1, PGAM1, PGAM2, PRKAA1, PRKCD, EIF2AK2, PTAFR, PURA, RAN, RARA, RBM4, UPF1, RGS2, RPL38, RPS3, RPS4X, RPS6KA1, RPS6KB1, RPS6KB2, RXRA, S100A9, SRP9, TNFRSF1A, TSC1, UCN, EIF4H, ZFP36, PICALM, NSMAF, MAPKAPK5, EIF4EBP3, EIF3G, EIF3J, EIF4G3, CDC123, EIF2B3, EIF2B2, EIF2B5, RQCD1, CNOT8, QKI, EIF2AK3, EIF5B, EIF4A3, RBM8A, NR1H4, TRAP1, EIF1, EIF1B, ABCA7, PRG3, EIF3M, USP16, IGF2BP3, KHDRBS1 |
2012 | GO:1902582 | 0.00 | 1.43 | 105.10 | 129 | 291 | single-organism intracellular transport | ABCA1, ABCA2, ABL1, ADRB2, ATP1A2, ATP7B, KIF1A, BICD1, VPS51, CALM1, CALM3, CASQ1, CASQ2, CD4, CD63, CDC42, CDX2, CCR5, CYBA, DDIT3, DIAPH1, EDNRA, EIF4E, EMP2, PTK2B, FCER1G, FGR, GLE1, XCR1, GSTM2, HHEX, HIF1A, AGFG1, HRC, HTR2C, IL13, IL13RA2, ITGB1, ITPR1, ITPR2, KIF5A, KIT, KLC1, NTSR1, OPA1, P2RX3, P2RX4, P2RX5, PCM1, CHMP1A, PDE4D, PIK3C3, PLN, PRKCE, PRKCZ, PTPN6, RAB5B, RAB13, RAB5C, RDX, UPF1, RPGR, CLIP1, RYR1, RYR2, RYR3, S100A13, CCL21, XCL1, SEL1L, SRSF1, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SLN, SOD1, STAR, STXBP2, HSP90B1, TRPC1, TRPC3, TRPM2, TSC1, TSG101, UBB, TRPV1, LAT2, ALMS1, TUBA1A, STAM, CLTCL1, PICALM, UXT, EEA1, SSNA1, STX16, STX10, SRSF9, RAB11A, TRPA1, RAB9A, KIF3B, GSTO1, ATG5, VPS26A, ABCG1, GPRASP1, IFT140, SNX17, GAB2, ZC3H11A, SMG7, RBM8A, HDAC6, TOM1, COL4A3BP, ARL4C, DDX39A, STAM2, TRDN, NXF1, RNPS1, RAB32, IFT27, KIF3A, BVES, CORO1A |
2013 | GO:0051234 | 0.00 | 1.42 | 344.16 | 415 | 991 | establishment of localization | ABCA3, ABCB7, ABCA4, ACO1, ACTB, ACTG1, ADCY3, ADCY6, ADCY9, ADD1, PARP4, AGXT, AHSG, AMBP, ANXA6, ANXA11, APLP1, APOH, APRT, AQP5, AQP6, AQP7, ARG1, ARR3, ASGR1, ATF4, ATP1A1, ATP1A3, ATP12A, ATP1A4, ATP1B3, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP4A, ATP4B, ATR, AVPR2, CCND1, BCL2A1, HCN2, BDKRB2, C3, CA2, CA4, CA5A, CACNA2D1, CACNB3, CACNB4, CAV2, CBL, CD5, CD6, CD81, CDH17, CDK2, CDO1, CEBPE, AKR1C4, CHUK, CLCA1, CLCN5, CLCN6, CLCN7, CLCNKA, CLCNKB, CLNS1A, ACKR2, CNGA1, COL3A1, COMT, COX4I1, COX5B, COX6A1, COX6B1, COX7A1, COX7C, COX8A, COX15, CRAT, CREBL2, CRY2, CRYM, CTNS, CXADR, CYB5A, CYBB, DBI, ACE, DPP6, TSC22D3, EIF2S1, EIF2S3, ESR1, FABP2, FABP6, FABP7, ACSL1, ACSL4, FCGR1A, FCGRT, FCN2, FOLR3, FYN, G6PC, SLC37A4, GABRA4, GABRA5, GABRA6, GABRE, GABRG1, GABRR1, GABRR2, GFAP, GIF, GJA3, GJA4, GJB1, GPC3, GLRA2, GM2A, GOT2, GPM6A, UTS2R, GRK6, GRB2, GRIA4, GRID1, GRID2, GRIK3, GRIN2A, GUCA1B, GUCA2B, HBA2, HBM, HBD, HBE1, HBG1, HBQ1, HIP1, HP, HPX, HRH2, HTR3A, ICAM1, INPPL1, ITGAV, KCNA1, KCNA3, KCNA4, KCNA10, KCNC1, KCND2, KCND3, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ12, KCNJ13, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN1, KCNQ1, KCNS2, LCAT, LIMK1, LIPC, LRPAP1, LTF, MAL, MAP6, MEP1B, SEPT2, NTF3, OLR1, ORM2, OSBP, P2RY2, P2RY4, P2RY6, PAWR, SERPINA5, PDE4B, ENPP2, ENPP3, PER1, ATP8B1, PIGR, PIK3CB, FXYD3, PRKAA1, RELN, PTEN, ABCD3, ABCD4, RAC1, RAP1GAP, RARA, RBP1, RBP2, RCVRN, RHAG, RHCE, RHD, ABCE1, RPS6KB1, RXRA, S100A1, S100A6, S100A8, S100A9, SCN1A, SCN2A, SCN3A, SCN4B, SCN5A, SCN7A, SCN8A, SCN10A, SCNN1A, SCNN1B, SCNN1G, SCO1, SEC14L1, SELE, SEMG1, SFRP4, SFTPD, SGK1, SLC2A3, SLC2A4, SLC2A5, SLC4A1, SLC5A2, SLC5A3, SLC5A5, SLC6A6, SLC6A7, SLC7A1, SLC7A4, SLC9A2, SLC9A3, SLC9A5, SLC10A1, SLC10A2, SLC12A2, SLC12A3, SLC13A1, SLC34A1, SLC20A1, SLC25A1, SLCO2A1, SLCO1A2, SLC22A1, SLC22A3, SLC22A5, STAT5B, STC1, SYP, SYPL1, TAF7, SERPINA7, DYNLT3, ICAM5, TMPRSS2, TP73, TPD52, TPT1, CCT3, TRPC4, TRPC5, TUB, TULP1, UBE3A, SUMO1, UPK3A, UQCRC1, UQCRH, VAV1, VDAC2, VTN, WFS1, ZFPL1, SLC30A2, SLC30A3, SLC30A4, LAPTM5, KCNAB1, TUSC3, SLC25A16, SLC7A5, SLC14A2, SLC10A3, DYSF, SRPX, SOAT2, PIK3R3, KHSRP, KCNK5, SLC4A4, PEA15, RIPK1, NRP1, SLC5A6, EIF2S2, CPNE1, KALRN, SLC13A2, CLDN10, RGN, SLC16A6, SLC16A5, SLC16A4, SYNGR3, SLC6A5, SLC28A1, COX7A2L, SLC24A1, SLC16A7, KCNAB3, SLC33A1, PDLIM7, TRIP10, CD163, SLC22A6, SLC22A8, LIPG, SLC22A13, KCNK6, ABCG2, QKI, AKAP7, SLC4A7, SLC4A8, MPDU1, RIN1, CLCA2, CROCC, LAPTM4A, EIF4A3, PIEZO1, CKAP5, HEPH, ELMO1, OSBPL2, SV2B, OXSR1, SLC12A6, KCNE2, ABI1, KCNE3, HCN4, ABCC5, ABCB6, ABCC9, ABCF2, COX17, ARPC5, ARPC4, ARPC3, ARPC1B, TSPAN1, ARPC2, SGK2, AKAP9, G3BP1, WASF2, TNK2, PRG4, SLC35B1, KCNMB2, SIGMAR1, ABCA7, ABCA10, ABCA9, ABCA8, CACNG2, SPON2, VAV3, BAIAP2, SLC30A9, SLC25A17, SLC9A6, FBLN5, ARL6IP5, ARPC1A, SLC35A1, SLC34A2, SLCO1B1, IGF2BP3, EBP, CORIN, ARPP19, SLC26A1, SLC22A7, USP20, CFHR4, SERINC3, UQCR11, SLC27A5, SLC27A4, SLC27A2, STON1, SLC35D2, WWP1, SLC7A9, ABCB8 |
2014 | GO:0043623 | 0.00 | 1.42 | 100.79 | 123 | 270 | cellular protein complex assembly | ABL1, ADD1, ADRB2, ALDOB, ANG, ANGPT1, ARF1, ARF6, ARHGAP6, ARL2, ATP6V0A1, BBS4, CAPG, CAPZA1, CAPZB, CASQ1, CASQ2, CAV3, CD3E, CD36, CENPA, CENPE, CENPF, AP2S1, COX15, CSNK1D, CYBA, DIAPH1, DIAPH2, DNAH5, EFNA5, CTTN, EPS8, EPS15, PTK2B, FGA, FGG, GOLGA2, GRB2, HCK, HCLS1, NRG1, HIP1, UBE2K, ICAM1, INSIG1, TNPO1, IPO5, NUP98, PARK2, PFN1, PFN2, PRKCD, PRKCE, EIF2AK2, PSMD4, PSMD5, PTK2, RAB1A, RAC1, RDX, RGS2, RPS3, CLIP1, SCO1, CCL21, CCL24, SGK1, SNAP25, SNCA, SPAG1, STXBP1, TAZ, TBCA, TBCD, TMOD1, TRAF2, TUBG1, UVRAG, VBP1, VDAC2, VIL1, ZNF207, PICALM, GAS7, CADPS, SYNJ1, WASF1, LATS1, AIFM1, SNAP29, SLIT2, PICK1, BAG4, PDE4DIP, NUP93, TOMM20, SNAP91, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, ABI2, TUBGCP3, SEC24B, CDC42EP2, BAIAP2, ARPC1A, ARFGEF1, CDC42EP3, AVIL, NRG3, TUBGCP2, TMED2, ADRM1, UBE2C, STMN2, TPPP, CORO1A |
2015 | GO:0005975 | 0.00 | 1.42 | 142.15 | 173 | 384 | carbohydrate metabolic process | ABO, PARP4, ALDH2, ALDOB, ALDOC, ARCN1, AREG, ART1, ART3, ATF4, CACNA1A, CANX, CD44, CD59, CGA, CHIT1, CLN5, COPA, CRY1, CSNK1D, VCAN, CSPG4, CTSZ, CYB5A, DAD1, DCN, CYB5R3, DYNC1H1, DYNC1I1, DYNC1I2, DPAGT1, ENO2, ENO3, EXTL1, GPC4, FUT6, FUT8, SLC37A4, GALC, GALE, B4GALNT1, GALNS, GALNT1, GAPDH, GPC3, GM2A, GMDS, GOLGB1, GOT2, GRIA1, GUSB, HEXA, HEXB, HMMR, ONECUT1, IDH3A, IDS, INPPL1, KCNE1, KCNJ11, LDHA, LDHC, LMAN1, LUM, MAN2B1, CHST6, MDH1, MDH2, MGAT2, MGAT3, NUP88, NUP98, OAS2, OMD, OGDH, OGN, OVGP1, PCK2, CFP, PGK1, PGM3, PPP2R5D, PPP6C, PRKACB, PRKACG, PRKCSH, PSEN1, RAB1A, RPN2, SDC2, SDC4, SDF2, TRAPPC2, SEL1L, SGSH, SI, ST6GAL1, ST8SIA1, SLC2A3, SLC2A4, SLC2A5, SLC5A2, SLC9A1, SLC25A1, UAP1, SPAM1, TRAPPC10, UGDH, UGT2B4, UGT2B7, USF1, VEGFB, TUSC3, NUP214, AAAS, PARG, SLC25A12, USO1, DYNLL1, GALNT4, B4GALT4, B4GALT3, B3GALT2, DPM2, PAPSS2, PAPSS1, COPB2, B4GALT6, B4GALT5, COG1, GSTO1, CHST3, GAL3ST1, MPDU1, GOSR1, SEC22B, GOSR2, NUP155, HS2ST1, SDC3, NUP93, HS3ST3B1, HS3ST3A1, HS3ST1, ABCC5, GPC6, PREB, CHST4, SLC25A13, AKR1A1, TMEM5, SPON1, SEC24B, COG5, SEC23A, SLC35A1, YKT6, DCTN6, FUT9, NUP50, SEC24A, SLC26A1, UGT2A1, KDELR1, OS9, TMED2, SDS, SLC35D2, KERA, ADAMTS13, ADAMTS5, NUPL2, ADAMTS7 |
2016 | GO:0051171 | 0.00 | 1.41 | 750.89 | 879 | 2029 | regulation of nitrogen compound metabolic process | ABCA1, ABCA2, ABL1, ACTL6A, ACTN1, ACVR1, ACVR2A, ACVR2B, ACVRL1, ADM, ADRA2A, ADRB2, AEBP1, JAG1, AGTR2, NR0B1, ALK, ALX3, ANXA3, APAF1, BIRC2, XIAP, BIRC5, APLP1, AREG, PHOX2A, ARNT, ARNTL, ASCL1, ASCL2, ASS1, ATM, RERE, ATOH1, ATR, ATRX, AVP, AVPR2, BACH1, BARD1, BAX, CCND1, BCL7A, PRDM1, BMI1, BMP1, BMP3, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, BRCA1, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTG1, BTK, TSPO, CALCR, CALM1, CALM3, CAMK4, CAMK2A, CAT, RUNX2, RUNX1T1, CBFB, CBL, CCNB1, CCNC, CCNE1, CCNH, CCNT1, CCNT2, CCT6A, CD3D, CD80, CD86, TNFSF8, CD36, CD38, CD81, CDA, CDK11B, CDC5L, CDC42, CDH1, CDK2, CDK8, CDK9, CDKN1A, CDKN2A, CDX1, CDX2, CDX4, CEBPE, CENPB, CENPF, CGA, CHD1, CHD2, CHD3, CHD4, CHEK1, CHUK, CLK1, CLK3, COL1A1, CREB1, ATF2, CREBL2, CRH, CRX, CRY1, CRY2, CRYM, CSNK2A1, CSNK2A2, CTH, CTNND2, CYLD, DAB2, DGKQ, DCN, DDIT3, DDX5, DFFA, DHFR, DKC1, DLX5, DLX6, DNM2, DNMT1, DNMT3B, DRD3, DRD5, ARID3A, RCAN1, TSC22D3, DUSP1, DYRK1A, E2F2, E2F4, E2F6, E4F1, EBF1, ECM1, EDA, S1PR1, LPAR1, EDNRA, EFNA1, EGR2, EGR3, EGR4, ELAVL2, ELK1, EMX1, EMX2, EN1, EP300, EPHA5, ERCC1, EREG, EYA4, ERCC3, ERCC4, ERCC6, ERF, ERG, ERN1, ESR1, ESRRG, ETS1, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA1, EYA2, EYA3, EZH1, F2R, F2RL1, FBN1, EFEMP1, FGF4, FGF7, FGFR3, FGFR4, FLI1, AFF2, FRK, FSHB, FSHR, NR5A2, NR5A1, FZD2, GABPA, GALR1, GAS6, GATA4, GATA6, GCG, KAT2A, NR6A1, GDF9, GFI1, GHRH, GHRHR, GPC3, GLP1R, GNAL, GNAS, GPD1, GPS2, ARHGAP35, GRM8, GSC2, GTF2F1, GTF2I, GTF3A, BRF1, GUCA1A, GUCA1B, GUCA2A, GUCA2B, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, H2AFZ, HBE1, HCK, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIF1A, HIP1, HIVEP2, ZBTB48, HLF, HLX, HMGN1, HMGA1, NR4A1, HMX1, HMX2, FOXA2, HNF4G, ONECUT1, HNRNPC, HOXC10, HOXC11, HOXD3, HOXD8, HOXD9, HOXD10, HOXD11, HOXD12, PRMT2, HES1, HSF4, HSPA8, HSP90AA1, HSP90AB1, ICAM1, IFI16, SP110, IFNA2, IFNG, IGBP1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL1B, IL10, IL17A, ILK, ING2, INSIG1, INSL3, IRAK1, IRAK2, IRF1, IRF2, IRF5, ISL1, ITGA3, JARID2, JUN, JUND, KCNK2, KIT, KPNA1, KPNA2, KRAS, AFF3, ABLIM1, LMO1, LTF, LUM, EPCAM, SMAD6, SMAD7, SMAD9, MAZ, MEOX2, KITLG, MGMT, CIITA, ATXN3, AFF1, FOXO4, CITED1, PPP1R12A, TONSL, NRL, YBX1, NTF3, NTRK1, NTRK2, NTRK3, NVL, OAS3, OGG1, SIX6, ORC1, ORC2, OTX1, OTX2, OVOL1, P2RX4, P2RX7, P2RY1, P2RY11, PCSK6, SERPINE1, PALM, PAM, PAWR, PAX3, PAX4, PAX9, PBX1, PCK1, PCNA, CHMP1A, PDE4D, PDE8A, PEX14, PF4, PFDN1, ATP8B1, PFN1, PGR, PHF2, PIM1, PRRX1, PPID, PPM1A, PPP1R8, PPP2R1A, PPP4C, PPP3R1, PRKAG1, PRKAR1A, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK8, RELN, PSEN1, PTEN, PTGER4, PTGIS, PTHLH, PTPN1, RAC1, RAD21, RAD51, RAD52, RAF1, RARB, RB1, RBBP6, RBL1, RBL2, RCVRN, RELB, DPF2, REST, RFX1, RFX2, RFX3, RFXAP, RLF, RNF6, RPA2, RREB1, RRM2, RXRG, RYR2, S100A1, S100A8, S100A11, S100A12, SALL1, SATB1, XCL1, TRAPPC2, SET, SETMAR, SFPQ, SFRP4, SFRP5, SRSF4, SRSF6, SRSF7, SFSWAP, SGK1, SHC1, SIM2, SIX1, SIX3, SLC9A1, SLC11A1, SMARCA1, SMARCA2, SMARCA4, SMARCC2, SMARCD1, SMARCD3, SMARCE1, SNAI1, SNAPC1, SNAPC2, SNAPC3, SNRNP70, SOD2, SON, SOX1, SOX2, SOX3, SOX9, SOX10, SOX11, SOX12, SP1, SP4, SP100, SPIB, SREBF1, SRF, SRPK2, SRY, TRIM21, SSRP1, STAT1, STAT2, STAT3, STAT4, STAT5B, STAT6, SUPT4H1, SUPV3L1, SUV39H1, TAF2, TAF4B, TAF5, TAF6, TAF7, TAF10, TAF13, TAL1, TAL2, TBL1X, TBP, HNF1A, ZEB1, ZNF354A, NR2F1, NR2F2, KLF10, TMF1, TMPO, TNFAIP3, TNNI2, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, CCT3, TRIP6, TSC2, TSG101, TTF1, TULP3, TWIST1, TNFSF4, TNFRSF4, TYMS, UBB, UBE2D2, UBE2L3, UBE2V2, UBE3A, SUMO1, UBTF, UCP1, SCGB1A1, UNG, NR1H2, USF1, VAV1, VIP, VIPR2, TRPV1, WFS1, WHSC1, WNT1, WNT2, WNT11, XRCC5, YY1, ZFP37, ZFPL1, ZIC1, ZIC2, ZNF3, ZNF711, ZNF7, ZNF8, CNBP, ZNF708, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZSCAN21, ZNF41, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF91, ZNF99, ZNF124, ZNF132, ZNF136, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF217, ZNF223, ZNF224, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, ZXDA, PRDM2, CSDE1, FZD5, BRPF1, ARHGEF5, ZNF212, BRD3, CSRP3, FOSL1, FGF23, HMGA2, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, SMC1A, USP9Y, HIST1H4I, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, CUL4A, CUL3, CUL2, FOXN1, KLF11, SMARCA5, OGT, ITGA8, IKBKG, IKBKAP, HAT1, GAS7, CBX4, CAMK1, PIR, BLZF1, KHSRP, STK16, RGS20, RUVBL1, KLF7, CDK13, RFXANK, TP63, CHRD, PDE5A, DYNLL1, SRSF9, TRADD, EDF1, URI1, EED, RIPK1, RIPK2, TRIM24, SAP30, HESX1, CFLAR, HDAC3, TSC22D1, KAT2B, PER3, TAX1BP1, BUD31, CPNE1, PHOX2B, HIST1H3F, HIST1H2AG, USP13, RPS6KA4, TNFSF18, TAF1C, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, USP2, RGN, PDLIM1, SMC3, AIFM1, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, SLC33A1, AURKB, VAPB, CCPG1, ITGB1BP1, ZNF235, KLF4, COPS2, TRIP11, HMGN3, CER1, CIAO1, RECQL5, ZRANB2, HAND1, ZNF264, FHL5, IL27RA, AKAP6, ONECUT2, LITAF, TBPL1, ZNF254, GTPBP1, GABBR2, CLOCK, SOX13, RBM39, AKAP12, RNF14, ABCG1, GUCA1C, ZNF592, CTR9, ZNF516, KDM4A, VGLL4, BZW1, DHX34, ST18, ZNF646, SETD1A, HDAC4, ZFYVE16, BCLAF1, MAML1, RNF40, KEAP1, TSC22D2, RB1CC1, ARHGEF11, ZEB2, ZBTB24, ZNF518A, SETDB1, SUPT7L, RNF10, ZBTB5, NR1I3, NR1D2, RBX1, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, RAD50, PREB, ZNF263, ZNF256, SORBS3, RNF41, CALCRL, TRIM13, OLIG2, TRIB1, ZNF443, DENND4A, SF3B4, IRX5, RAMP2, RAMP3, FSTL3, SAP18, APBB3, TNIP1, IKZF1, TRIM22, HMG20B, HMG20A, KLF2, CITED2, PIAS3, IFITM3, RAPGEF3, RBM14, PPIE, MAD2L2, SLC30A9, TRIM38, CAP1, CREB3, CARM1, SEMA4D, ZNF211, DEAF1, SIVA1, CCT7, CCT4, CCT2, ERN2, ERLIN1, HEXIM1, RBCK1, ARID3B, TRIM16, TXNIP, RAD51AP1, DMRT2, CTCF, CERS1, TBR1, STAG2, RAI1, PHTF1, AHCYL1, ZMYND11, ZBTB6, ZNF234, ZNF266, ZNF273, ZNF275, RUVBL2, ARID5A, MALT1, BRD8, PAPOLA, RNPS1, PRDX3, YWHAQ, ASCC3, COPS5, CCDC85B, VAX1, GTF2A1L, PIM2, WWP1, WWP2, SOX30, WDR5, PRDM7, PRDM5, KAT7, ERLIN2, SOX21, PSIP1, STRAP, ZNF277, SUPT16H, CHEK2, DDX20 |
2017 | GO:0006469 | 0.04 | 1.41 | 46.75 | 57 | 125 | negative regulation of protein kinase activity | ABL1, ADAR, ADARB1, BMP4, CAV3, CDKN1A, CDKN2A, CHAD, CISH, DCN, GADD45A, DUSP1, DUSP4, DUSP5, EPHA1, GNAQ, SFN, GP1BA, GPS2, HHEX, HMGCR, HSPB1, IGF1R, IL1B, ILK, PCP4, PPP1R1A, PPP2R1A, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCD, PSEN1, PTEN, PTPN1, PTPN6, PTPRJ, RB1, RGS2, SERPINB3, TAF7, NR2F2, TNFAIP3, TP73, TSC2, CUL3, KAT2B, SOCS3, RGN, LATS1, ITGB1BP1, SOCS6, TRIB1, SPRY1, HEXIM1, UBE2C |
2018 | GO:0043043 | 0.00 | 1.41 | 129.41 | 157 | 346 | peptide biosynthetic process | AARS, ACO1, AKT2, ANG, APP, ATF4, BCL3, CD28, CDK4, CIRBP, DAPK3, DAZ1, DDX1, DDX6, DIO2, EEF1A2, EEF1B2, EEF2, EIF1AX, EIF2S1, EIF2B1, EIF2S3, EIF4A1, EIF4E, EIF4EBP1, EIF4G1, EIF4G2, EIF5, EIF5A, ELAVL1, EPRS, ERBB2, ETF1, PTK2B, FAU, GAPDH, GGT7, GRB7, HARS, HNRNPD, HSPB1, IGF1, IGFBP5, ILF3, EIF3E, CAPRIN1, RPL10A, CNOT2, PA2G4, PCSK5, PER1, EIF2AK2, PTAFR, PURA, RARA, RBM4, UPF1, RGS2, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL36AL, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS6KA1, RPS6KB1, RPS6KB2, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, RXRA, S100A9, SLC25A1, SOX11, SRP9, SRP14, SRP19, SRP68, SSR1, TARS, TSC1, TUFM, UCN, UCP1, EIF4H, ZFP36, AIMP2, SLC25A16, MAPKAPK5, DENR, SLC25A12, EIF4EBP3, DDX3Y, EIF3G, EIF3J, EIF4G3, CDC123, EIF2B3, EIF2B2, EIF2B5, EIF2S2, RPL14, EIF1AY, RQCD1, CNOT8, RPL23, QKI, EIF2AK3, EEF1E1, GTPBP1, EIF5B, EIF4A3, RBM8A, TRAP1, SLC25A13, SLC25A15, EIF1, EIF1B, TNIP1, PRG3, SLC25A17, EIF3M, USP16, IGF2BP3, KHDRBS1, FARS2, SEC61B, COPS5, RPL35 |
2019 | GO:0044702 | 0.00 | 1.41 | 163.35 | 198 | 444 | single organism reproductive process | ACVR1, ADCY3, ADRB2, AMHR2, BIRC3, AREG, ATM, ATP1A4, AXL, BAD, BBS2, BBS4, CCND1, BMP6, BMPR1A, BOK, BRCA2, BRDT, BTG1, CASP5, CCNB1, CD9, CDC20, CDC25C, CDK2, CLGN, CFTR, CKS2, CLU, COL9A3, CXADR, CYLC1, CYLC2, DAZ1, ACE, DHCR24, DIAPH2, DNM2, DUSP1, PHC2, ERCC1, ERCC4, ETS1, ETV5, FANCA, FANCC, FANCD2, ACSL4, PTK2B, B4GALNT1, GAMT, GATA6, NR6A1, B4GALT1, GLRA1, GOLGA2, GPR3, HIST1H1T, HIST1H1A, HSD17B10, HEXB, HMGCS1, HOXD9, HOXD10, HOXD11, AGFG1, IDH1, IL1A, ING2, INSL3, KRT9, LRMP, SMAD1, CD46, SMCP, NUMA1, ODF1, OR1D2, OVGP1, OVOL1, PAFAH1B2, PAFAH1B3, SERPINA5, PDE3A, PGAM2, PGM3, PPP2R1A, PRKACB, PRKACG, PRKAG1, PRKAR1A, PTN, RAD1, RAD21, RAD23B, RAD51, RAD51C, RAD51B, RAD51D, RGS2, RPS6KB1, RRM1, SALL1, SBF1, SIAH1, SMARCA2, SMARCA4, SOX2, SOX3, SPAG1, SPAG4, SPAM1, SPINK1, SRD5A1, SRY, SSTR2, STAR, AURKA, STYX, TAF4B, TBP, TMF1, TNP2, TOP2A, TOP2B, NR2C2, CCT3, TRPC3, TRPM2, TSPY1, TUBG1, TYRO3, UBB, ZAN, WNT2B, XRCC2, YY1, ZNF35, ZNF148, ZP2, DNALI1, CSDE1, AAAS, USP9X, SMC1A, USP9Y, TPST2, FKBP6, RUVBL1, AKR1C3, PDE5A, DYNLL1, ADAM15, EIF2S2, HERC2, RNF8, RGN, SMC3, FAM50A, EXO1, ZW10, QKI, PICK1, ADAMTS2, GAL3ST1, TBPL1, CLOCK, SPAG6, SPATA2, REC8, BCL2L10, BCL2L11, SMC4, ACTR2, RAD50, IRX5, FSTL3, CITED2, SEMA3A, TUBGCP3, CRTAP, DEAF1, PRDX4, CCT7, CCT4, CCT2, CCT6B, STAG3, STAG2, TOB2, TUBGCP2, ADAM28, PRSS21, PIM2, SOX30, HSF2BP, CIT, DDX20 |
2020 | GO:0009059 | 0.00 | 1.41 | 986.89 | 1138 | 2654 | macromolecule biosynthetic process | AARS, ABCA1, ABCA2, ABL1, ABO, ACO1, ACTL6A, ACTN1, ACVR1, ACVR2A, ACVR2B, ACVRL1, PARP4, ADRA2A, ADRB2, AEBP1, JAG1, AGTR2, NR0B1, AKT2, ALAS2, ALK, ALX3, ANG, ANXA3, BIRC2, XIAP, BIRC5, APOA1, APP, ARCN1, AREG, PHOX2A, ARNT, ARNTL, ART1, ART3, ASCL1, ASCL2, ATF4, ATM, RERE, ATOH1, ATR, ATRX, BACH1, CCND1, BCL2, BCL3, BCL7A, PRDM1, BMI1, BMP1, BMP3, BMP6, BMP8B, BMPR1A, BMPR2, BRCA1, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTG1, BTK, CAMK4, CAMK2A, CANX, CAT, RUNX2, RUNX1T1, CBFB, CBL, CCNC, CCNE1, CCNH, CCNT1, CCNT2, CCT6A, CD3D, CD3E, CD4, CD28, CD80, CD86, TNFRSF8, TNFSF8, CD36, CD38, CD59, CD81, CDK11B, CDC5L, CDC25A, CDC25C, CDC42, CDH1, CDK2, CDK4, CDK8, CDK9, CDKN1A, CDKN2A, CDX1, CDX2, CDX4, CEBPE, CENPB, CENPF, CGA, CHD1, CHD2, CHD3, CHD4, CHEK1, CHUK, CIRBP, CLU, COPA, COX4I1, COX5B, COX6A1, COX6B1, COX7C, COX8A, CREB1, ATF2, CREBL2, CRX, CRY1, CRY2, CRYM, CSNK1D, CSNK2A1, CSNK2A2, CSTF3, CTH, CTNND2, CTSZ, CYLD, DAB2, DAD1, DGKQ, DAPK3, DAZ1, DDIT3, DDX1, DDX5, DDX6, DHFR, DIO2, DKC1, DLX5, DLX6, DYNC1H1, DYNC1I1, DYNC1I2, DNM2, DNMT1, DNMT3B, DNTT, DPAGT1, DRD3, ARID3A, RCAN1, TSC22D3, HBEGF, DUSP1, DUT, E2F2, E2F4, E2F6, E4F1, EBF1, TYMP, ECM1, EDA, S1PR1, EEF1A2, EEF1B2, EEF2, EFNA1, EGR2, EGR3, EGR4, EIF1AX, EIF2S1, EIF2B1, EIF2S3, EIF4A1, EIF4E, EIF4EBP1, EIF4G1, EIF4G2, EIF5, EIF5A, ELAVL2, ELAVL1, ELK1, EMX1, EMX2, EN1, EP300, EPHA5, EPRS, ERBB2, EREG, EYA4, ERCC3, ERCC6, ERF, ERG, ERN1, ESR1, ESRRG, ETF1, ETS1, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA1, EYA2, EYA3, EZH1, F2RL1, PTK2B, FAU, FBN1, EFEMP1, FCER2, FEN1, FGF4, FGF7, FGFR3, FGFR4, FLI1, FRK, FSHB, NR5A2, NR5A1, FUT6, FUT8, FZD2, GABPA, B4GALNT1, GALR1, GALNT1, GAPDH, GAS6, GATA4, GATA6, GCG, KAT2A, NR6A1, GDF9, GFI1, GHSR, GLB1, GLS, GMDS, GOLGA2, GOLGB1, SFN, GPS2, GPX2, GRB7, GRIA1, ARHGAP35, GSC2, GTF2F1, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, GYS2, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, H2AFZ, HARS, HBE1, HCK, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIP1, HIVEP2, ZBTB48, HLF, HLX, HMGN1, HMGA1, NR4A1, HMX1, HMX2, FOXA2, HNF4G, ONECUT1, HNRNPC, HNRNPD, HOXC10, HOXC11, HOXD3, HOXD8, HOXD9, HOXD10, HOXD11, HOXD12, PRMT2, HES1, HSF4, HSPA8, HSPB1, ICAM1, IFI16, SP110, IFNA2, IFNG, IGBP1, IGF1R, IGF2, IGFBP5, RBPJ, IL1A, IL12B, IL15, IL17A, ILF3, ILK, ING2, INHA, INS, INSIG1, EIF3E, IRAK1, IRAK2, IRF1, IRF2, IRF5, ISL1, ITGA3, JARID2, JUN, JUND, KCNE1, KCNK2, KDR, KIT, KRAS, AFF3, LCAT, ABLIM1, LIPC, LMAN1, LMO1, LTF, EPCAM, CAPRIN1, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MEOX2, MGAT2, MGAT3, KITLG, ATXN3, AFF1, FOXO4, CITED1, PPP1R12A, DRG1, RPL10A, TONSL, CNOT2, NRL, YBX1, NTF3, NTRK1, NTRK3, NUP88, NUP98, NVL, OAS2, OGG1, SIX6, ORC1, ORC2, ORC4, ORC5, OTX1, OTX2, OVOL1, P2RY1, PA2G4, PCSK6, PRDX1, SERPINE1, PAM, PARK2, PAWR, PAX3, PAX4, PAX9, PBX1, PCK1, PCNA, CHMP1A, PDE8A, PER1, PEX14, PF4, CFP, PFDN1, ATP8B1, PFN1, PGGT1B, PGM1, PGM3, PGR, PHF2, PHKG1, PIGC, PIM1, PRRX1, PPID, PPM1A, PPM1B, PPP1R8, PPP2R1A, PPP3R1, PPP5C, PPP6C, PRG2, PRIM2, PRKAA1, PRKAG1, PRKAR1A, PRKCD, PRKCI, PRKD1, PRKCQ, PRKCSH, PRKCZ, MAPK8, EIF2AK2, RELN, PSEN1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PTAFR, PTEN, PTGIS, PTHLH, PTMA, PTMS, RAD1, PURA, RAB1A, RAC1, RAD21, RAD51, RAF1, RAN, RANBP2, RARA, RARB, RB1, RBBP6, RBL1, RBL2, RBM4, RBMS1, RELB, UPF1, DPF2, REST, REV3L, RFC3, RFC4, RFC5, RFX1, RFX2, RFX3, RFXAP, RGS2, RGS12, RHEB, RLF, RNF6, RPA2, RPA3, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL36AL, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS6KA1, RPS6KB1, RPS6KB2, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, RREB1, RRM1, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A11, S100A12, SALL1, SATB1, CCL20, CCL21, XCL1, SDF2, TRAPPC2, SEL1L, SET, SETMAR, SFPQ, SFRP4, SFRP5, SRSF1, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SFSWAP, SFTPD, SGK1, SHC1, ST6GAL1, ST8SIA1, SIM2, SIX1, SIX3, SLC2A4, SLC9A1, SLC11A1, SLC25A1, SMARCA1, SMARCA2, SMARCA4, SMARCC2, SMARCD1, SMARCD3, SMARCE1, SNAI1, SNAPC1, SNAPC2, SNAPC3, SNCA, SNRPE, SNRPF, SOD2, SOX1, SOX2, SOX3, SOX9, SOX10, SOX11, SOX12, SP1, SP4, SP100, UAP1, SPIB, SPN, SREBF1, SRF, SRP9, SRP14, SRP19, SRP68, SRY, TRIM21, TROVE2, SSR1, SSRP1, STAT1, STAT2, STAT3, STAT4, STAT5B, STAT6, SUPT4H1, SUV39H1, TAF2, TAF4B, TAF5, TAF6, TAF7, TAF10, TAF13, TAL1, TAL2, TARS, TBL1X, TBP, HNF1A, ZEB1, ZNF354A, NR2F2, KLF10, TRAPPC10, TMF1, TMPO, TNFAIP3, TNFRSF1A, TNNI2, TOP1, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, CCT3, TRIP6, TSC1, TSC2, TSG101, TTF1, TUFM, TULP3, TWIST1, TNFSF4, TNFRSF4, TYMS, U2AF1, UBB, UBA7, UBE2D2, UBE2L3, UBE3A, SUMO1, UBTF, UCP1, SCGB1A1, UGP2, NR1H2, USF1, VAV1, VEGFB, EIF4H, WFS1, WHSC1, WNT1, WNT2, WNT11, XRCC5, YY1, YWHAZ, ZFP36, ZFP37, ZFPL1, ZIC1, ZIC2, ZNF3, ZNF711, ZNF7, ZNF8, CNBP, ZNF708, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZSCAN21, ZNF41, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF91, ZNF99, ZNF124, ZNF132, ZNF136, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF217, ZNF223, ZNF224, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, ZXDA, PRDM2, CSDE1, PAX8, FZD5, BRPF1, EPM2A, AIMP2, ARHGEF5, ZNF212, TUSC3, BRD3, NUP214, SLC25A16, CSRP3, FOSL1, FGF23, AAAS, HMGA2, CDK2AP1, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, SMC1A, USP9Y, HIST1H4I, PICALM, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NSMAF, DYRK2, CUL4A, CUL3, CUL2, FOXN1, KLF11, SMARCA5, OGT, ITGA8, IKBKG, IKBKAP, HAT1, GAS7, CBX4, CAMK1, PIR, BLZF1, MAPKAPK5, DENR, KHSRP, STK16, RGS20, SLC25A12, RUVBL1, KLF7, USO1, CDK13, RFXANK, TP63, EIF4EBP3, CHRD, DDX3Y, DYNLL1, EIF3G, EIF3J, EIF4G3, SRSF9, GALNT4, B3GALT2, TRADD, EDF1, URI1, EED, RNGTT, RIPK1, RIPK2, TRIM24, DPM2, SAP30, HESX1, CFLAR, HDAC3, TSC22D1, KAT2B, PER3, CDC123, TAX1BP1, EIF2B3, EIF2B2, EIF2B5, EIF2S2, BUD31, CPNE1, PHOX2B, HIST1H3F, HIST1H2AG, USP13, RPS6KA4, TNFSF18, TAF1C, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, RPL14, EIF1AY, USP2, RGN, PDLIM1, RQCD1, SMC3, CCNE2, CBFA2T2, ATG12, DYRK1B, CTDP1, COX7A2L, ARHGEF2, DDX21, SLC33A1, AURKB, CCPG1, ITGB1BP1, COPB2, ZNF235, KLF4, COPS2, TRIP11, HMGN3, GTF3C5, GTF3C4, GTF3C3, CNOT8, RPL23, CER1, COG1, CIAO1, RECQL5, RECQL4, ZRANB2, HAND1, ZNF264, QKI, EIF2AK3, FHL5, ATG5, ONECUT2, PIGL, GAL3ST1, LITAF, TBPL1, EEF1E1, GOSR1, TMEM59, ZNF254, SEC22B, GTPBP1, GOSR2, CLOCK, SOX13, RBM39, RNF14, ABCG1, NUP155, ZNF592, CTR9, ZNF516, EIF5B, KDM4A, VGLL4, NUP93, BZW1, ST18, ZNF646, SETD1A, HDAC4, ZFYVE16, KIAA0101, BCLAF1, EIF4A3, MAML1, KEAP1, TSC22D2, RB1CC1, ARHGEF11, GINS1, ZEB2, ZBTB24, ZNF518A, EPM2AIP1, SETDB1, SUPT7L, RNF10, ZBTB5, RBM8A, NR1I3, NR1H4, NR1D2, RBX1, DMTF1, CASP8AP2, NR2E3, ACOT8, ZBTB33, GNE, PIGK, RAD50, PREB, ZNF263, TRAP1, CHST4, SLC25A13, SLC25A15, ZNF256, SORBS3, RNF41, TRIM13, EIF1, OLIG2, PRG4, TRIB1, ZNF443, DENND4A, IRX5, RAMP3, FSTL3, SAP18, EIF1B, APBB3, TNIP1, IKZF1, TMEM5, TRIM22, ABCA7, HMG20B, HMG20A, KLF2, CITED2, PRG3, PIAS3, IFITM3, SPON1, SEC24B, RBM14, PPIE, MAD2L2, SLC30A9, COG5, TRIM38, SLC25A17, EIF3M, SEC23A, CREB3, CARM1, SEMA4D, ZNF211, DEAF1, ATG7, RNASEH2A, SLC35A1, ARFGEF1, SIVA1, CCT7, CCT4, CCT2, SORBS1, ERN2, USP16, ERLIN1, HEXIM1, RBCK1, ARID3B, IVNS1ABP, TRIM16, TXNIP, SPHAR, IGF2BP3, YKT6, DMRT2, KHDRBS1, CTCF, FARS2, RRAGA, DCTN6, FUT9, CERS1, TBR1, STAG2, RAI1, PHTF1, NUP50, ZMYND11, ZBTB6, ZNF234, ZNF266, ZNF273, ZNF275, RUVBL2, ARID5A, MALT1, BRD8, PAPOLA, RNPS1, DBF4, PRDX3, KDELR1, SEC61B, OS9, TMED2, YWHAQ, ASCC3, COPS5, CCDC85B, VAX1, GTF2A1L, PIM2, PAPD7, ADRM1, WWP1, WWP2, SOX30, HSF2BP, WDR5, ADAMTS13, ADAMTS5, NUPL2, PRDM7, PRDM5, KAT7, GLMN, ERLIN2, SOX21, PSIP1, STRAP, ADAMTS7, ZNF277, SUPT16H, CHEK2, DDX20, RPL35 |
2021 | GO:0051259 | 0.01 | 1.40 | 70.88 | 86 | 191 | protein oligomerization | ACACB, ACADL, ACADS, ACHE, ADSL, ALAD, ANXA5, ANXA6, APAF1, ARG1, ASL, CAT, CAV2, ENTPD2, CDA, CRYZ, CTH, DECR1, DNM1, DPAGT1, DPYSL3, STOM, GJA5, GJB1, GLS, GLUL, GOLGA2, GPX3, HSD17B10, HMGCL, HMGCR, HPRT1, HSF4, IGF1R, IMPDH2, IRAK1, KCNA1, KCNA2, KCNA3, KCNA4, KCNA10, KCNC1, KCND2, KCND3, KCNJ2, KCNJ12, KCNS2, KCNS3, LIPC, OAT, OTC, P2RX3, P2RX4, P2RX7, PAM, PLN, RAD51, RPS19, RXRA, RXRG, RYR3, SHMT1, SHMT2, SLC9A1, SLC34A1, SLC22A1, SOD2, SPAST, TRIM21, SYT1, TAF10, TNFAIP3, TP73, CLPP, TP63, TRPA1, SLC22A6, EIF2AK3, KEAP1, AASS, TRIM22, OLFM4, USP16, MALT1, DHRS4, UPK1A |
2022 | GO:0060255 | 0.01 | 1.40 | 71.16 | 87 | 209 | regulation of macromolecule metabolic process | AARS, ACHE, ACO1, APOA1, ARF1, ARR3, C7, CCNG1, CDC25A, CDC25C, CKS1B, CKS2, CTSZ, DDX6, DHX9, DIO2, EEF1A2, EIF2B1, EPHA2, EIF4A1, EIF4G1, EIF4G2, EIF5, EPHB1, ETF1, FGR, FUT8, G6PC, GCGR, GFAP, GHRHR, GNAS, HRC, HSP90AA1, KHK, TNPO1, PRDX1, CFP, PPP1R2, PPP2CB, PPP2R1B, PPP2R2A, PPP2R5D, PRG2, RAC2, RAD23B, RAG2, RPE65, RPL38, SORT1, STYX, TOP1, HSP90B1, UTY, UVRAG, VRK2, EIF4H, YWHAZ, NSMAF, DDX3Y, EIF3G, EIF3J, EIF4G3, DLK1, CDC123, EIF2B2, DIRAS3, CCNE2, LIPG, APBA3, EIF5B, KIAA0141, DDX46, NUAK1, FEM1B, TRAP1, ATP6AP2, EIF1, DDX39A, EIF1B, ZER1, EIF3M, TOB2, ARPP19, SEC24A, CDC37, AKAP13 |
2023 | GO:0022411 | 0.03 | 1.40 | 55.12 | 67 | 150 | cellular component disassembly | ACTL6A, ADRB2, ANXA5, BNIP3L, TSPO, COX8A, CSNK2A2, EIF2S1, CTTN, STOM, FANCC, FANCF, FCGR3B, SLC37A4, GABRA5, BLOC1S1, KAT2A, GOLGA2, HIF1A, KCNK3, KRT15, MDH1, NTHL1, NUP88, NUP98, P2RX5, PARK2, PEX13, SERPINB10, RANBP2, SFRP4, SLC1A3, SLCO1A2, SLC22A3, SNRPD1, SNRPF, SREBF1, STAT2, NR2C2, U2AF1, UBB, VRK1, ZBTB17, ZNF189, FZD5, NUP214, AAAS, CHAF1B, RUVBL1, BECN1, BANF1, CCNB2, ATG12, CHST3, ATG5, NUP155, NUP93, ATG13, PHYHIP, TOMM20, FGFBP1, ATG7, NUP50, HSF2BP, NUPL2, CDC37, ADAMTS7 |
2024 | GO:0006325 | 0.00 | 1.40 | 119.09 | 144 | 320 | chromatin organization | ACTB, ACTL6A, ATM, RERE, CCND1, BMI1, BRCA1, BRCA2, CCNB1, CDK2, CDK4, CDK9, CHD1, CHD2, CHD4, CHEK1, ATF2, DAPK3, DDB2, DNMT1, DNMT3B, PHC1, EP300, EYA4, ESR1, EYA1, EYA2, EYA3, EZH1, GCG, KAT2A, GFI1, GPS2, HIST1H2AE, HIST1H2AD, H2AFZ, HLCS, HMGN1, FOXA2, HNRNPC, PRMT2, HSF4, IL1B, ING2, ISL1, JARID2, PAX3, PER1, PHF2, PPP5C, PRKAA1, PRKCD, PRKD1, MAPK8, RAG1, RAG2, RB1, RBL1, RBL2, REST, SALL1, SATB1, SETMAR, SFPQ, SKP1, SMARCA1, SMARCA2, SNCA, SOX1, SOX2, SREBF1, AURKA, SUPT4H1, SUPV3L1, SUV39H1, TAF5, TAF7, TAF10, TBL1X, TBP, TOP1, TTF1, TWIST1, UBTF, UCN, KDM6A, UTY, VRK1, WHSC1, PRDM2, BRPF1, BRD3, KDM5C, BAP1, GFI1B, HIST1H2AK, HIST2H2AC, OGT, IKBKAP, CBX4, TP63, EED, SAP30, HDAC3, KAT2B, HIST1H2AG, RPS6KA4, TAF1C, TAF1B, TAF1A, AURKB, HMGN3, GTF3C4, ATG5, CHD1L, CLOCK, CTR9, KDM4A, SETD1A, HDAC4, RNF40, SETDB1, SUPT7L, USP3, NR1H4, HDAC6, SAP18, IKZF1, HMG20B, HMG20A, RBM14, CARM1, ATG7, USP16, TRIM16, ZMYND11, RUVBL2, ARID5A, BRD8, WDR5, PRDM7, PRDM5, KAT7, WDHD1 |
2025 | GO:0044712 | 0.01 | 1.39 | 94.94 | 115 | 261 | single-organism catabolic process | ACHE, ACTL6A, ADRA2A, ADRB2, AMBP, ANXA5, AOX1, APOA1, APOH, STS, BLVRA, BLVRB, BNIP2, BNIP3, BNIP3L, TSPO, DAGLA, CDA, CDKN2A, CLPS, COX8A, CSNK2A2, CYP2A6, CYP3A4, ACE, DPEP1, DPYD, TYMP, EIF2S1, CTTN, STOM, FABP2, FABP6, FABP7, FANCC, FANCF, FCGR3B, SLC37A4, GABRA5, GALC, BLOC1S1, KAT2A, GPLD1, DNAJB2, IDH1, IL1B, KCNK3, KRT15, DNAJB9, MDH1, ATXN3, P2RX5, PAFAH1B2, PAFAH1B3, PAFAH2, PARK2, SERPINB10, PIK3C3, PRKACB, PRKACG, PRKCE, PSMC1, PSMC2, PSMC3, PSMC4, SEL1L, SFRP4, SGTA, SLC1A3, SLCO1A2, SLC22A3, SNRPD1, SNRPF, SREBF1, STAT2, NR2C2, HSP90B1, U2AF1, UBB, UGT2B4, WFS1, TRIM25, ZBTB17, ZNF189, RNF103, FZD5, RAB7A, CHAF1B, RUVBL1, HSD17B6, BECN1, USP13, USP14, ATG12, LIPG, CHST3, ATG5, NUP93, ATG13, PHYHIP, IST1, TOMM20, FGFBP1, HDAC6, TRIM13, MARCH6, ATG7, ERLIN1, USP19, SEC61B, OS9, HSF2BP, CDC37, ERLIN2, ADAMTS7 |
2026 | GO:0051056 | 0.02 | 1.39 | 62.09 | 75 | 166 | regulation of small GTPase mediated signal transduction | A2M, ABCA1, ABL2, APOA1, ARF6, ARHGAP4, ARHGAP6, ARHGDIB, BCR, CDC42, CHN1, CHN2, COL3A1, DNM2, LPAR1, F2R, F2RL1, FGD1, GDI1, GDI2, RAPGEF1, ARHGAP35, NRG1, IGF1, ITGA3, ITGB1, KRAS, KITLG, NTRK1, PPP2CB, RELN, RAC1, RAC2, RAC3, RAF1, RAP1GAP, RASA2, RDX, SIPA1, SOS1, SOS2, TSC2, VAV1, ARHGEF5, SHOC2, CUL3, OGT, DGKZ, TNK1, ARHGEF7, KALRN, ARHGEF1, DGKI, ARHGEF2, CYTH3, GPR55, TRIP10, SLIT2, ARHGAP29, ARHGEF6, RALGPS1, ARHGAP32, ARHGEF11, ARHGEF17, FARP2, RHOBTB1, ARHGAP25, RASA4, FARP1, SPRY1, VAV3, ARFGEF2, ARFGEF1, STAMBP, AKAP13 |
2027 | GO:0006310 | 0.04 | 1.39 | 49.64 | 60 | 133 | DNA recombination | ABL1, ACTL6A, ATM, ATR, ATRX, BARD1, BRCA1, BRCA2, CD28, CDK2, CHEK1, ERCC4, IFNG, RBPJ, IL10, KPNA1, KPNA2, TONSL, PPP4C, RAD1, RAD21, RAD52, RAG1, RAG2, SFPQ, STAT6, SUPV3L1, TOP2A, TOP2B, TSN, TNFSF4, UBB, UBE2V2, SUMO1, UNG, WHSC1, XRCC4, XRCC5, YY1, SHFM1, HIST1H4I, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, RUVBL1, HERC2, RNF8, EXO1, RECQL5, RECQL4, IL27RA, REC8, PSMD14, RBM14, RAD51AP1, RUVBL2 |
2028 | GO:0035556 | 0.00 | 1.38 | 104.25 | 126 | 296 | intracellular signal transduction | AGTR2, AKT2, AVP, AVPR2, BAG1, BLK, BMP1, BMP3, BMP6, BMP8B, BTK, CAMK4, CBLB, CD80, CD86, CCR5, CREB1, ATF2, CTSH, DGKA, DGKB, DGKQ, DAPK3, DCX, RCAN1, EIF4EBP1, ELK1, EPHA7, EPHB1, FCGR1A, FYB, GDF9, GNAI1, GNAZ, CXCL1, GUCY2C, GUCY2F, GUCY2D, NR4A1, HRC, INHA, ITGAV, KCNH2, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, FOXO4, NRTN, OXTR, PRDX1, PDE4A, PDE4D, PFKFB1, PIK3C2B, PI4KA, PLN, PPP1R1A, PPP2R5D, PRKACB, PRKACG, PRKAR1A, PRKAR2A, PRKAR2B, PRKCI, PRKCSH, PTAFR, PTPN13, RBM4, RGS12, RPS6, RPS6KA1, RPS6KB1, RPS6KB2, RYR1, RYR3, S100A1, SGK1, SRPK2, STK10, STYX, NR2C2, TSG101, TUFT1, TYRO3, TYROBP, VRK2, LAT2, CORO2A, SCG2, ANP32A, NSMAF, DCHS1, ADAM15, RGS11, INPP4B, RPS6KA4, TRPA1, RGN, LATS1, STK17B, STK17A, AKAP7, GDF15, CDC42BPB, TTI1, SLK, RB1CC1, GAB2, NUAK1, OXSR1, ZBTB33, SH2B3, SGK2, ATP6AP2, RNF41, TRIB1, RCAN2, TRAIP, PRDX4, NRG3, PDE10A, COPS5, RCAN3, NUDT4 |
2029 | GO:0048285 | 0.00 | 1.37 | 124.54 | 149 | 333 | organelle fission | ABL1, ADCY3, BIRC5, ATM, ATRX, BAX, BMP4, BNIP3, BRCA2, BRDT, BUB1B, CAV2, CCNB1, CCNF, CCNG1, CCNG2, CD28, CDK11B, CDC20, CDC25A, CDC25C, CDC27, CDC42, CDK2, CDK3, CENPE, CENPF, CETN1, CHEK1, CKS2, CSNK2A1, CSNK2A2, DAPK3, DCN, DRD3, DUSP1, E4F1, EDN3, EPS8, EREG, ERCC4, FANCA, FANCD2, FGFR3, GOLGA2, GPR3, HGF, IGF1, IGF1R, IGF2, IL1A, IL1B, ING2, INS, KDR, KIF25, PPP1R12A, SEPT2, NUMA1, NUP88, OPA1, PARK2, CHMP1A, PDE3A, PPP2R1A, PPP5C, PRKAR1A, PTEN, RAD1, PEX19, RAD21, RAD51, RAD51C, RAD51B, RAD51D, RAN, RB1, RPL24, RPS3, CLIP1, SMARCA4, AURKA, DYNLT3, DYNLT1, TOP2A, TOP2B, TTK, UBB, VRK1, WEE1, XRCC2, ZNF207, NUP214, HMGA2, CLTCL1, USP9X, SMC1A, CUL3, FKBP6, CDC14A, RUVBL1, CDK13, BECN1, CDC23, RAB11A, PEX11A, CDC16, RNF8, LATS1, SMC3, CCNB2, CTDP1, ARHGEF2, ZW10, AURKB, KIF3B, RECQL5, MAD2L1BP, DLGAP5, CKAP5, CUL7, KLHL21, DCLRE1A, REC8, ACOT8, TOM1L1, SMC4, ACTR2, RAD50, AKAP8, KATNB1, ANAPC10, TUBGCP3, MAD2L2, SSSCA1, USP16, STAG3, STAG2, ARPP19, TUBGCP2, JTB, TXNL4A, KIF2C, PIM2, PAPD7, UBE2C, CIT, ZWINT, CHEK2 |
2030 | GO:1901566 | 0.05 | 1.37 | 49.08 | 59 | 135 | organonitrogen compound biosynthetic process | ACADM, ACHE, AGTR2, ALAD, ALAS1, ALAS2, ALDH9A1, ALDH3A2, APOA1, TSPO, CHAT, CHKB, CKM, COX15, CPOX, CSNK1G2, DBH, DTYMK, ESD, ACSL3, FGF7, B4GALNT1, GSTM1, GSTM2, GSTZ1, HMBS, IDO1, LCAT, SLC11A2, OAZ1, OAZ2, P2RX1, P2RX7, PCYT1A, PRKAA1, PRKCD, PRKD1, QDPR, ST8SIA1, SMS, SNCA, TNFRSF1A, UROS, BBOX1, NSMAF, PDXK, SUCLA2, KYNU, VAPB, GSTO1, GAL3ST1, TBPL1, PTDSS1, ABCB6, COL4A3BP, AKR1A1, CEPT1, PEMT, CERS1 |
2031 | GO:0010564 | 0.03 | 1.36 | 59.24 | 71 | 160 | regulation of cell cycle process | BBS4, BCL2, BID, BMP4, BRCA2, BUB1B, CALM1, CALM3, CAV2, CCNF, CDC5L, CDC20, CDC25C, CDC27, CENPE, CENPF, CHEK1, CRY1, CSNK2A1, CSNK2A2, DAPK3, DUSP1, E4F1, ERCC3, FGFR3, GPR3, PRMT2, NUBP1, OVOL1, CHMP1A, PDE3A, PIK3C3, PIM1, PPP2R1A, PRKAR1A, PRKCQ, PTPN6, RAD1, RPA2, SIX3, SKP1, SMARCA4, SOX9, SOX11, ADAM17, TTK, UVRAG, XPC, ZNF207, SMC1A, CUL1, DGKZ, CDC14A, CDK13, CDC23, CDC16, SMC3, ZW10, MAD2L1BP, CUL7, KLHL21, PDCD6IP, TOM1L1, FEM1B, CTDSPL, ANAPC10, RBM14, MAD2L2, PDPN, CTCF, STAG2 |
2032 | GO:0006811 | 0.04 | 1.36 | 54.11 | 65 | 149 | ion transport | ABCA2, ABCA4, AGXT, ALB, ABCD1, ANXA1, APOA1, ASNA1, AVP, BDKRB2, CA2, CA4, CA5A, CCK, CD36, AKR1C4, CHRM1, CLNS1A, CRY2, CTNS, ACE, FABP6, ACSL1, ACSL3, FOLR3, SLC37A4, GLS, GOT2, HBA2, LTF, SEPT2, NTRK2, P2RY1, P2RY2, P2RY4, P2RY6, PRKCD, ABCD3, RXRA, SLC2A1, SLC6A11, SLC6A12, SLC6A13, SLC25A1, SLCO2A1, SLCO1A2, SNAP25, STXBP1, SYT1, FGF23, SLC10A3, CLDN10, ABCG1, NR1H4, ABCC5, ATP9A, ABCC4, ABCA7, ARL6IP5, SLCO1B1, GIPC1, CPLX1, SLC22A7, SLC27A4, SLC27A2 |
2033 | GO:0048468 | 0.02 | 1.36 | 77.31 | 93 | 219 | cell development | ACTN1, ACVR1, AKT2, ANG, ANGPT2, ATM, AXL, BBS2, BCL2L1, BMP1, BMP3, BMP8B, BRCA2, BTK, CASP9, CBFB, SERPINH1, CD9, CFTR, COL11A1, DIAPH2, EDN3, EDNRA, EIF2B1, ELAVL1, EP300, ERCC1, ERG, EYA1, FANCC, FANCG, FLI1, GATA6, GHRHR, HEXB, AGFG1, HSF4, RBPJ, IL15, ING2, INHA, INS, INSL3, ITGA4, KCNJ10, KDR, LAMA5, CNOT2, PAX3, PIP4K2A, PPP2R1A, PTPN6, RAB1A, RHAG, RPS6KB1, RPS19, S100A4, S100A8, S100A9, CCL21, ST6GAL1, SIX1, SMARCA2, SMARCA4, TAF4B, TAL1, TMF1, TYRO3, WNT11, HMGA2, FZD4, SOX14, ITGA8, ADAM15, ALDH1A2, EIF2B3, EIF2B2, EIF2B5, RNF8, LATS1, QKI, EIF2AK3, GDF15, TBPL1, SPAG6, ZEB2, REC8, ABI1, WASF2, KLF2, DEAF1, FERMT2, DDX20 |
2034 | GO:0030030 | 0.00 | 1.36 | 240.38 | 285 | 653 | cell projection organization | ABL1, ACTB, ACTG1, ADAM10, ADM, ANGPT1, APOA1, APP, ARAF, AREG, RERE, ATOH1, ATP2B2, ADGRB1, BBS1, BBS2, BCL2, KLF5, TSPO, CACNA1A, CACNB3, CACNB4, CALM1, CALM3, CALU, CAMK2A, CAPG, CCK, CD72, CDC20, CDH1, CHN1, CHRNB2, AP2S1, CLU, CLTA, CNP, COL3A1, COL4A3, COL4A5, COL5A2, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2RB, CSNK1D, CSNK2A1, CSNK2A2, CTNNA1, CTNNA2, CYLD, DCX, DHFR, DLG3, DLX5, DNM1, DNAH5, EPYC, HBEGF, ECM2, DUSP5, E2F4, S1PR1, EFNA3, EFNA4, EFNB1, EGR2, EPHA2, EMP1, EMP2, EMP3, EMX1, EPHA1, EPHA5, EPHA8, ERBB2, EREG, ETV4, EXT1, ACSL4, FGD1, FGF3, FGF4, FGF5, FGF7, FGFR3, FGFR4, BLOC1S1, GFRA1, GRB2, GRID2, GRIN2A, ONECUT1, HPRT1, HSPA8, HSP90AA1, HSP90AB1, ICAM1, IL2RA, INPPL1, ISL1, ITGA1, ITGA5, ITGA9, ITGAV, ITGB4, JUN, KIF5A, KRAS, LAMA5, ABLIM1, MAP6, MARK3, KITLG, NUBP1, SEPT2, SLC11A2, NRCAM, NRTN, NTF3, NTF4, NTN3, OGN, OTX2, PEBP1, PCM1, ATP8B1, PRRX1, PPP5C, PRKCZ, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTPRA, PTPRM, RAB5A, RAB13, RAC3, RAF1, RAP2A, RASA2, RB1, RDX, RFX3, RPGR, RPL24, RPS6KA1, RXRA, RYK, S100A6, S100B, SCN5A, SDC2, SDC4, SDCBP, SHC1, SIAH1, STIL, SLIT3, SNAP25, SOD1, SOS1, SOS2, SPAG1, SPAST, TROVE2, AURKA, STRN, STXBP1, CNTN2, TBCE, DYNLT1, TOP2B, TRPC1, TRPC3, TRPC4, TRPC5, TSC1, TULP1, TYROBP, UBB, UCN, WEE1, ZIC2, FGF23, USP9X, PICALM, CUL3, CNTNAP1, ITGA8, GAS7, CDC14A, KLF7, UNC5C, SSNA1, NUMB, DYNLL1, PEA15, NRP2, CPNE1, PHOX2B, WASF1, RPS6KA4, KALRN, ATP6V0D1, S1PR2, KLF4, NREP, SNAP29, SLC9A3R1, NRXN3, ARHGEF6, CHST3, ATG5, ONECUT2, PSMF1, BAG4, NRG2, SPAG6, FEZ2, CROCC, IFT140, ARHGEF11, FARP2, PSMD6, RBX1, ABI1, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN2, NUBP2, AKAP9, RASA4, FARP1, PSME3, PSMD14, ABCC4, SPON2, SEC24B, VAV3, SLC9A6, CAP1, ATG7, ARPC1A, ARFGEF1, DPYSL4, TBR1, CHL1, FRS3, RAB10, AFG3L2, IFT27, RAB35, VAX1, KIF3A, CORO1A |
2035 | GO:0044087 | 0.03 | 1.36 | 63.53 | 76 | 172 | regulation of cellular component biogenesis | ABL1, ACVRL1, ADD1, BIRC2, BLK, BRCA1, KLF5, CAPG, CAPZA1, CAPZB, CHRNB2, CLDN7, CYLD, DAPK3, ACE, EPHA2, EIF4EBP1, EPHA7, EPS8, GFAP, GHSR, RAPGEF1, HCLS1, DNAJB2, HSPA8, HSP90AA1, INS, INSIG1, LCAT, SMAD6, CHMP1A, PEX14, ATP8B1, PPM1A, PRKAA1, PRKCD, PRKCZ, EIF2AK2, PTEN, PTK2, PEX5, RAB5A, RAF1, RAP1GAP, RB1, REST, SELP, SGK1, SIX1, SNAI1, SNCA, STXBP1, TBCD, TMOD1, TNFRSF1A, VDAC2, FZD5, RAB7A, STAM, NSMAF, LATS1, SLIT2, RAB33A, ATG5, BAG5, SNCAIP, FEZ2, RAPGEF2, IFT140, SLK, FARP2, SEC24B, RBM14, ARFGEF1, AVIL, STMN2 |
2036 | GO:0006631 | 0.03 | 1.36 | 66.13 | 79 | 177 | fatty acid metabolic process | ACAA1, ACACB, ACADL, ACADM, ACADS, ACADSB, ACADVL, ACLY, ABCD1, ALOX12, ALOX15B, BRCA1, C3, DAGLA, CBR1, CNR1, CPT1B, CPT2, CRAT, CYP2A6, CYP2A13, CYP2F1, DECR1, DPEP1, ECH1, FAAH, ACSL1, ACSL3, ACSL4, GGT7, GPX1, HPGD, INS, INSIG1, IVD, LIPC, LIPE, FADS3, LTA4H, PAM, PDK4, PEX7, PEX13, PRKAA1, PRKAG1, PRKAR2B, PTGIS, PTGS1, ABCD3, RNPEP, ACSM3, SNCA, SREBF1, STAT5B, STK11, TNFRSF1A, TYRP1, PDHX, ACOX2, ACOX3, AKR1C3, CH25H, FADS2, QKI, EIF2AK3, ACOT8, PRG3, ACAA2, ECI2, SLC25A17, ERLIN1, PDPN, FAXDC2, ACOT2, SLC27A5, SLC27A4, SLC27A2, RPP14, ERLIN2 |
2037 | GO:0044710 | 0.00 | 1.36 | 121.32 | 146 | 373 | single-organism metabolic process | ABCA2, ABCA4, ABO, ACAT2, ADAR, PARP4, AGTR1, ARCN1, AREG, ART1, ART3, BACH1, BARD1, BBS4, OPN1SW, CANX, CCNC, CCNH, CD28, CDC5L, CGA, TPP1, CLN5, COPA, CSNK1D, CTSZ, DAD1, DDX1, DYNC1H1, DYNC1I1, DYNC1I2, EEF1A2, EYA4, ERCC3, ERCC5, FANCA, FANCD2, FANCE, FANCB, FANCG, FGR, GALNT1, GATA6, OPN1MW, GOLGA2, GOLGB1, HMGN1, HMGA1, HPX, IL1RN, IL10, IL15, KCNE1, KPNA2, LMAN1, SMAD3, MGAT3, MGMT, TONSL, PPP4C, PPP6C, PRKCSH, RAD1, RAB1A, RAD21, RAD23B, RAD51C, RAD51B, RAD52, RB1, RBL1, RBL2, OPN1LW, RPN2, SDF2, TRAPPC2, SFTPB, SLC12A1, SUMO3, SSRP1, STAT6, SUPV3L1, NR2F2, TRAPPC10, TOP2A, TOP2B, UBE2V2, SUMO1, UVRAG, TRPV1, XPA, XPC, XRCC2, XRCC4, YY1, ZNF91, SHFM1, TUSC3, SMARCA5, IRS4, PARG, DGKZ, COPS3, CDC14B, USO1, DYNLL1, GALNT4, EDF1, HERC2, EXO1, COPB2, COPS2, COG1, RECQL5, RECQL4, IL27RA, GOSR1, TMEM59, SEC22B, CHD1L, GOSR2, KIAA0391, NR1D2, REC8, PREB, CHST4, TMEM5, SPON1, PPIE, VAV3, SLC30A9, COG5, RNASEH2A, ARFGEF1, RAD51AP1, YKT6, DCTN6, COPS8, KDELR1, TMED2, ASCC3, COPS6, PAPD7, ADAMTS13, ADAMTS5, SUPT16H |
2038 | GO:0010256 | 0.00 | 1.36 | 122.67 | 146 | 328 | endomembrane system organization | ABCA1, AKT2, ARF6, ARL1, ASNA1, ATP1B3, BBS1, BBS2, BCL2L1, BSG, CALCR, CASQ1, CAV2, CAV3, CCNB1, CDC42, CDH1, CLCN3, CLU, CREB1, CSNK1D, DAB2, DNM1, DNM2, DPP6, EPHA2, EMP2, F2R, ACSL3, FCER1G, FLOT2, FYB, GAK, GAS6, BLOC1S1, GOLGA2, GOLGA4, GOLGB1, AGFG1, IFNG, ITGA3, ITGB1, KRT18, LAMA5, LMAN1, NUP88, NUP98, P2RX7, P2RY1, PALM, CHMP1A, ATP8B1, PIK3C3, PPP2R1A, PPP2R2A, PRKCD, PRKCI, PRKD1, PRKCZ, PTEN, RAB1A, RAB5B, RAB13, RAB27A, RAB5C, RAC1, RANBP2, RAP2A, RDX, CLIP1, S100A9, S100A10, SOD1, SPAG4, STXBP1, SURF4, SYP, TMF1, TNFRSF1A, TSC2, TSG101, TUB, TULP1, TULP2, TULP3, SUMO1, VIL1, VRK1, WRB, YWHAZ, NUP214, STAM, AAAS, UBL4A, DYSF, BLZF1, NUMB, VAMP8, STX16, RAB11A, BANF1, LIN7A, SYNJ1, ARHGEF7, AP3D1, SYT7, USP8, CCNB2, ZW10, VAPB, SLC9A3R1, NRXN1, COG1, EIF2AK3, TBPL1, TMEM59, BAG5, BAG4, NUP155, NUP93, RAPGEF2, IST1, CUL7, GOLGA5, DOPEY2, PDCD6IP, COL4A3BP, ARFRP1, STAM2, RAMP2, RAMP3, ZMPSTE24, TRDN, ABCA7, BAIAP2, STK25, ARFGEF2, ARFGEF1, SORBS1, NUP50, VAMP5, RAB10, TMED2, RAB31, RER1, NUPL2 |
2039 | GO:0044085 | 0.00 | 1.35 | 387.30 | 454 | 1054 | cellular component biogenesis | ABCA1, ABL2, ACACB, ACADL, ACADS, ACHE, ACTB, ACTG1, ACTN1, ADAR, ADRB2, ADSL, ALAD, ALDOB, ANG, ANGPT1, ANXA5, ANXA6, APAF1, APCS, BIRC3, BIRC5, APP, AREG, ARG1, ASL, ATP6V0A1, ATRX, BAD, BBS1, BBS2, BCL2, BICD1, DST, BYSL, CACNA1A, CASQ1, CASQ2, CAT, CCNB1, CD3E, CD3G, CD9, ENTPD2, CD59, CD151, CDA, CDH1, CDH3, CDH6, CDH7, CDH8, CDH9, CDH10, CDH12, CDH15, CDK2, CDKN2A, CLGN, CENPA, CENPE, CENPF, CFL2, CHD4, CHRNB4, CIRBP, AP2S1, CLNS1A, COL1A1, COL6A1, COL6A2, COL17A1, COX15, CLDN3, CRYZ, CSNK1D, CTH, CTNNA1, CTSZ, CYBA, DDX1, DDX6, DECR1, DIAPH1, DIAPH2, DKC1, DNM1, DNAH5, DYNC1H1, DPAGT1, E2F4, EIF2S3, EMP1, EMP3, STOM, EPRS, EPS15, FANCA, FANCC, ACSL3, FGA, FGD1, FGG, FLNC, CENPI, GAS6, GJA4, GJA5, GJB1, GLRA1, GLRA2, GLS, GLUL, GOLGA2, GPX3, GRB7, GRIA1, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, HIST1H1A, HSD17B10, HBA2, HBE1, NRG1, HIP1, UBE2K, HMGCL, HMGCR, HMGA1, ONECUT1, HPRT1, AGFG1, HES1, HSF4, HSPA4, IGF1R, IHH, IL1RAP, ILK, IMPDH2, INPPL1, EIF3E, IRAK1, ISG20, ITGA5, ITGB1, ITGB4, KCNA1, KCNA2, KCNA3, KCNA4, KCNA10, KCNC1, KCNC2, KCND2, KCND3, KCNJ2, KCNJ12, KCNS2, KCNS3, KPNA3, TNPO1, IPO5, KRT5, KRT19, LAMA3, LAMA5, LIM2, ABLIM1, LIPC, LMAN1, SMAD1, SMAD7, MYO1B, NUBP1, SEPT2, NRCAM, NUP88, NUP98, NVL, OAT, OTC, OTX2, P2RX1, P2RX3, P2RX4, PA2G4, PAM, PAWR, PCM1, PIK3C3, PLN, PPID, PPP2R1A, PPP2R1B, PPP5C, PPP6C, PRKAR1A, PRKCI, PSEN1, PSMD4, PSMD5, PVR, RAB1A, RAB13, RAC3, RAD51, RAD51C, RAD51B, RAD51D, RAD52, RAN, RAP2A, RFX3, RPGR, RPL3, RPL3L, RPL5, RPL7, RPL10, RPL11, RPL24, RPL34, RPL35A, RPL38, RPS6, RPS19, RPS27, RPS28, RRM1, RRM2, RSU1, RXRA, RXRG, RYK, RYR3, SCO1, SDF2, TRAPPC2, SEMG1, SET, SRSF1, SRSF5, SRSF6, SFSWAP, SH3BGR, SHMT1, SHMT2, SLC2A1, SLC34A1, SLC22A1, SNAP25, SNRPC, SNRPD1, SNRPD2, SNRPE, SNRPF, SOD2, SOX12, SPAG1, SPAST, SRPK2, TRIM21, AURKA, STK11, STRN, STXBP3, SURF6, SUV39H1, SYT1, TAF2, TAF7, TAF10, TAZ, TBCA, TRAPPC10, TMF1, TNFAIP3, TNNT2, TP73, HSP90B1, TRAF1, TRAF2, CCT3, TRIP6, TSPY1, TUBG1, UBB, USP4, UVRAG, VBP1, XRCC2, YWHAZ, ZNF148, ZNF207, CSRP3, HMGA2, CLPP, CHAF1B, HIST1H4I, PICALM, HIST1H2BG, HIST1H2BL, HIST1H2BN, HIST1H2BM, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SRPX, SOAT2, CUL3, SMARCA5, OGT, CNTNAP1, IKBKAP, HAT1, GAS7, CDC14A, PRPF18, DENR, RRP1, RUVBL1, USO1, CADPS, TP63, EIF3G, EIF3J, BECN1, SRSF9, DGAT1, TRADD, RIPK1, RAB11A, LIN7A, CFLAR, HDAC3, SYNJ1, CDC123, ARHGEF7, BSN, HIST1H3F, HIST1H2BJ, H1FX, TRPA1, TAF1B, RPL14, CLDN12, CLDN1, ATP6V0D1, PRPF3, AIFM1, ATG12, SCAF11, ZW10, REPS2, DDX21, AURKB, S1PR2, SNAP29, TAOK2, SLC9A3R2, SLC22A6, SLC9A3R1, KIF3B, ZFYVE9, CIAO1, DDX23, EIF2AK3, ARHGEF6, ONECUT2, TBPL1, SEC22B, GOSR2, PDE4DIP, CEP135, NUP93, EIF4A3, ATG13, IST1, TOMM20, SPOCK2, KEAP1, RB1CC1, KIAA0753, SNAP91, FIG4, REC8, RANBP9, NUBP2, PREB, AKAP9, AASS, FARP1, STAM2, ABCC4, RAMP2, TRIM22, ABCA7, NSA2, CD2BP2, EMG1, VAV3, PPIH, EIF3M, SEC23A, STK25, FBLN5, OLFM4, CCT2, SORBS1, USP16, TBL3, CTCF, CCT6B, USP39, NRG3, STAG3, SEC24A, WDR3, MALT1, DHRS4, TXNL4A, AFG3L2, SF3A3, TMED2, EBNA1BP2, FERMT2, RAB32, UPK1A, ADRM1, UBE2C, KRR1, KIF3A, SLC7A9, PSIP1, STRAP, CHEK2, DDX20, RPL35 |
2040 | GO:0051345 | 0.00 | 1.35 | 145.76 | 173 | 393 | positive regulation of hydrolase activity | AGTR2, AKT2, ALDH1A1, ALOX12, AMPH, APAF1, APP, ARHGAP4, ARHGDIB, BAD, BCR, BID, BNIP2, BOK, CASP1, CASP9, CAV2, CCK, CDKN2A, RCBTB2, CHN1, CHN2, COL4A3, CTGF, CTSH, S1PR1, EIF2B1, EPHA2, EPHA1, ERBB2, F2R, F3, PTK2B, FBLN1, FGD1, GCGR, GDI1, GDI2, GM2A, GNAS, GNAT1, GPLD1, FFAR1, RAPGEF1, ARHGAP35, HIP1, AGFG1, ICAM1, IFI16, IFNG, ITGA1, ITGB1, JUN, LLGL2, SMAD3, MAP3K5, PPP1R12A, SLC11A2, NTF3, NTRK3, P2RX1, PAWR, PCOLCE, PRKD1, MAPK8, PSME1, PSME2, RABIF, RANBP1, RANGAP1, RAP1GAP, RAP1GDS1, RASA2, REST, RGS2, RGS10, RGS12, RGS13, RGS16, RPGR, RSU1, S100A8, S100A9, S100A10, SBF1, SERPINB3, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SEMG1, SIPA1, SNCA, SOS1, SOS2, CDKL5, XCL2, TBCD, TRAF2, TSC1, TSC2, VAV1, WNT11, ARHGEF5, PICALM, BCAR3, RGS20, TRADD, RIPK1, CRADD, TNFSF10, RGS11, TNFRSF10B, TNFRSF10A, CFLAR, ASAP2, ARHGEF7, EIF2B3, EIF2B2, EIF2B5, HERC2, KALRN, AIFM1, RABEP1, ARHGEF1, ARHGEF2, CYTH3, TRIP10, ARHGAP29, EIF2AK3, ARHGEF6, AKAP6, STXBP5L, RIN1, RALGPS1, RAPGEF2, ARHGAP32, ACAP1, RAPGEF5, ARHGEF11, ARHGEF17, FARP2, SGSM2, RABGAP1L, ARHGAP25, TNFSF15, CASP8AP2, PDCD6, BCL2L10, BCL2L11, SH2D3C, SH2D3A, RASA4, FARP1, PSME3, PSMD14, DENND4A, CDC42EP2, VAV3, CREB3, SEMA4D, ARL6IP5, CXCL13, ARFGEF2, ARFGEF1, CDC42EP3, ADRM1, RAPGEF4, FZD10, AKAP13 |
2041 | GO:0006996 | 0.00 | 1.34 | 148.13 | 175 | 409 | organelle organization | ACTB, ALAS1, ARL1, ASNA1, RERE, ATP2A1, ATP2B2, CCND1, BLK, BMI1, CCK, CDK4, CHD1, CHD2, CIRBP, CLU, TPP1, CLN5, DDX1, DDX6, DHX9, DNM1, DYNC1I2, DNM2, TYMP, EYA4, ERCC3, ESR1, ETS1, FANCG, CENPI, GAA, GABPA, GAK, GFER, GOLGB1, GPS2, GRB7, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1T, HIST1H2AE, HIST1H2AD, H2AFZ, HIST1H1A, HEXB, HHEX, HMGN1, HMGCL, FOXA2, HPS1, HSPA9, IDUA, JUN, TNPO1, NUP98, PAX3, ATP8B1, PPID, PPP2CB, PPP2R2A, PRKAG1, PRKAR2B, PSEN1, PURA, RAB5B, RAB27A, RAB5C, RAD23B, RAG2, RANBP2, RBL1, RBL2, RLF, RPL3, RPL3L, RPL5, RPL10, RPL11, RPL38, RPS19, RPS27, SMARCA1, SMARCA2, SOD2, SOX1, SOX2, SRPK2, SUPT4H1, TBP, TOP1, TSPY1, TTF1, TUBA4A, SUMO1, UBTF, WRB, XPC, YY1, TUBA1A, BRD3, AAAS, UBL4A, HIST1H2AK, HIST2H2AC, HIST1H2BG, HIST1H2BL, HIST1H2BN, HIST1H2BM, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, CUL4A, SMARCA5, IKBKAP, COPS3, CBX4, BLZF1, TP63, BANF1, SAP30, ARHGEF7, HIST1H3F, HIST1H2AG, HIST1H2BJ, H1FX, TAF1C, TAF1B, TAF1A, USP8, COPS2, TRIP11, HMGN3, RAB33A, COG1, RECQL4, EIF2AK3, BAG5, CHD1L, NUP155, RB1CC1, GINS1, FIG4, GOLGA5, RBX1, DOPEY2, G3BP1, STAM2, ZMPSTE24, SAP18, IKZF1, HMG20B, HMG20A, STK25, ARFGEF2, EXOC5, YME1L1, NUP50, ZMYND11, RAB10, COPS8, PRDX3, TOMM34, ASCC3, COPS6, COPS5, RAB31, NUPL2, HPS5 |
2042 | GO:0071702 | 0.00 | 1.34 | 391.02 | 456 | 1072 | organic substance transport | ABCA3, ABL1, ABL2, ACHE, ACTL6A, ADAR, ALOX15B, ANG, ANGPT1, APOH, ARCN1, ARF1, ARL4D, ARF5, ARF6, RERE, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, AZGP1, BARD1, BBS1, BBS2, BBS4, BID, BMP4, BMPR1A, BNIP3L, BRCA1, BSG, BTF3, C3, VPS51, CALCR, CAMK4, CANX, CASP1, CASP5, CBLB, CD3G, SCARB2, CD58, CD63, CDC42, CDH1, CDKN1A, CDKN2A, CENPF, CHRM1, AP1S1, AP2S1, CLTA, COL1A1, COPA, CREBL2, CRP, CRY1, CRYM, CSE1L, CSF1R, CSNK2A2, CTSK, DAB2, DMBT1, DNM2, EDNRA, EGR2, EIF4E, EIF5A, CTTN, STOM, EPS15, ERBB2, ESR1, F2R, F2RL1, FBLN1, FAU, FGR, FYB, G6PC, SLC37A4, GAS6, KAT2A, GDF9, GDI1, GDI2, GFER, GIF, GJA5, GJB1, GPC3, GLE1, GM2A, GNAQ, GOLGA4, SFN, GPR26, HCLS1, NRG1, HHEX, HNMT, AGFG1, HES1, HSPA4, HSPA8, HSPA9, HSP90AA1, HSP90AB1, IFIT1, IFNA2, IGF1, RBPJ, IL1A, IL13, IL17A, ITGAV, ITGAX, ITGB1, JUN, KCNE1, KPNA1, KPNA2, KPNA3, KPNA4, KPNA5, TNPO1, IPO5, KRT18, LAMP2, LLGL2, LTBP2, SMAD3, RPL10A, TONSL, SLC11A2, NUP88, NUP98, OAZ1, OAZ2, OGG1, OR1D2, PAEP, PALM, PAM, SERPINA5, PCM1, CHMP1A, PCSK5, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX14, PIK3C3, PPID, PPP3R1, PRKAA1, PRKCI, PRKCZ, PSAP, PTPN1, PEX19, PEX5, RAB4A, RAB5A, RAB5B, RAB6A, RAB13, RAB27A, RAB27B, RABIF, RAB5C, RAC2, RAN, RANBP2, RANGAP1, UPF1, RHCE, RHD, RNASE2, RPGR, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS6KB1, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, CLIP1, RTN2, SORT1, S100A12, S100A13, CX3CL1, SDCBP, SEL1L, SFRP5, SRSF1, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SIX3, SLC2A3, SLC2A4, SLC2A5, SLC5A2, SLC9A1, SP100, SRP9, SRP14, SRP19, SRP68, SSR1, STAT3, STXBP2, STYX, TAF7, SERPINA7, DYNLT1, HSP90B1, TRAF2, TSC1, TSC2, TSG101, TST, TWIST1, TNFSF4, TNFRSF4, U2AF1, UBE2L3, UPK3A, VEGFC, VIL1, YWHAZ, ZIC1, ZBTB17, ZP2, FZD5, SCG2, RAB7A, ARHGEF5, NUP214, STAM, CUBN, AAAS, AKAP1, SLC14A2, CLTCL1, BAP1, FZD4, FZD7, DYRK2, OGT, PIK3R3, CAMK1, AP3B1, BLZF1, KHSRP, RGS20, RUVBL1, USO1, SSNA1, AKR1C3, DYNLL1, VAMP8, STX16, STX11, STX10, BECN1, PEA15, SRSF9, RIPK1, ADAM9, RAB11A, LIN7A, HDAC3, AP1S2, AP1M1, HERC2, AP3D1, SELENBP1, CDKL2, SEMA5A, RPL14, UNC119, ATP6V0D1, SEC22C, RABEP1, SLC28A1, IL1RL1, AP4M1, ARHGEF2, RASSF9, ZW10, ITGB1BP1, COPB2, TRIP11, SNAP29, TAOK2, RPL23, RAB33A, RAB9A, ZFYVE9, COG1, PEX16, QKI, AKAP6, ATG5, GOSR1, BAG4, RAB3D, APBA3, ATP6V1G1, SEC22B, VPS26A, GOSR2, AKAP12, RAB36, NUP155, IPO13, NUP93, TRAM2, IFT140, ACAP1, ZFYVE16, EIF4A3, ATG13, SNX17, CKAP5, TOMM20, KEAP1, C2CD5, ZC3H11A, OSBPL2, SMG7, SNAP91, FAM20B, RBM8A, DOPEY2, HDAC6, PDCD6IP, PDCD6, TOM1L1, TOM1, AP1M2, SAE1, COL4A3BP, KIF20A, PREB, ARFRP1, CALCRL, NUTF2, DDX39A, STAM2, RAMP2, RAMP3, SIGMAR1, APC2, KATNB1, ABCA10, ABCA9, ABCA8, PEMT, ARIH2, SEC24B, TACC3, COG5, NXF1, SEC23B, SEC23A, CREB3, APPBP2, CHERP, ATG7, ARFGEF2, ARFGEF1, SORBS1, TRIM16, TXNIP, EXOC5, IGF2BP3, YKT6, KHDRBS1, TNFSF13B, CCT6B, TRAF3IP2, NUP50, AHCYL1, ARPP19, VAMP5, SEC24A, CFHR4, RAB10, RNPS1, AFG3L2, KDELR1, AP3M2, SEC61B, TOMM34, OS9, TMED2, RAB32, KDELR2, KDELR3, IFT27, RAB35, RAB31, SLC35D2, WWP2, NUPL2, BTN3A1, CDC37, GLMN, AP4S1, NUDT4, RPL35, SEC63 |
2043 | GO:0016570 | 0.03 | 1.33 | 78.81 | 93 | 211 | histone modification | ACTL6A, ATM, BRCA1, BRCA2, CCNB1, CDK2, CDK9, CHEK1, ATF2, DDB2, DNMT1, DNMT3B, PHC1, EP300, EYA1, EYA2, EYA3, EZH1, GCG, KAT2A, GFI1, HIST1H1B, HLCS, PRMT2, IL1B, ISL1, JARID2, PER1, PPP5C, PRKAA1, PRKCD, PRKD1, MAPK8, RAG1, REST, SALL1, SATB1, SET, SETMAR, SFPQ, SKP1, SNCA, SREBF1, AURKA, SUV39H1, TAF5, TAF7, TAF10, TBL1X, TWIST1, UCN, VRK1, WHSC1, PRDM2, BRPF1, HMGA2, BAP1, GFI1B, OGT, HAT1, RUVBL1, EED, HDAC3, KAT2B, RPS6KA4, RNF8, BAZ1B, AURKB, GTF3C4, ATG5, CLOCK, CTR9, SETD1A, HDAC4, RNF40, SETDB1, SUPT7L, USP3, NR1H4, HDAC6, RBM14, CARM1, ATG7, USP16, TRIM16, CTCF, RUVBL2, ARID5A, BRD8, WDR5, PRDM7, PRDM5, KAT7 |
2044 | GO:1903506 | 0.00 | 1.33 | 702.76 | 804 | 1879 | regulation of nucleic acid-templated transcription | ABCA2, ABL1, ACTL6A, ACTN1, ACVR1, ACVR2A, ACVR2B, ACVRL1, ADRB2, AEBP1, JAG1, AGTR2, NR0B1, AKT2, ALK, ALX3, ANXA3, BIRC2, XIAP, BIRC5, APP, PHOX2A, ARNT, ARNTL, ASCL1, ASCL2, ATF4, RERE, ATOH1, ATRX, BACH1, CCND1, BCL3, BCL7A, PRDM1, BMI1, BMP1, BMP3, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, BRCA1, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTG1, BTK, CAMK4, CAMK2A, CAT, RUNX2, RUNX1T1, CBFB, CBL, CCNC, CCNE1, CCNH, CCNT1, CCNT2, CD3D, CD28, CD80, CD86, TNFSF8, CD36, CD38, CD81, CDK11B, CDC5L, CDH1, CDK2, CDK8, CDK9, CDKN2A, CDX1, CDX2, CDX4, CEBPE, CENPB, CENPF, CGA, CHD1, CHD2, CHD3, CHD4, CHEK1, CHUK, CLU, COL1A1, CREB1, ATF2, CREBL2, CRX, CRY1, CRY2, CRYM, CSNK2A1, CSNK2A2, CTH, CTNND2, CYLD, DAB2, DGKQ, DAPK3, DCN, DDIT3, DDX1, DDX5, DHFR, DLX5, DLX6, DNM2, DNMT1, DNMT3B, DRD3, ARID3A, RCAN1, TSC22D3, E2F2, E2F4, E2F6, E4F1, EBF1, ECM1, EDA, S1PR1, EFNA1, EGR2, EGR3, EGR4, ELAVL2, ELK1, EMX1, EMX2, EN1, EP300, EPHA5, ERBB2, EREG, EYA4, ERCC3, ERCC6, ERF, ERG, ERN1, ESR1, ESRRG, ETS1, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA1, EYA2, EYA3, EZH1, F2R, F2RL1, FBN1, EFEMP1, FGF4, FGF7, FGFR3, FLI1, FRK, FSHB, NR5A2, NR5A1, FZD2, GABPA, GALR1, GAS6, GATA4, GATA6, GCG, KAT2A, NR6A1, GDF9, GFI1, GPC3, GPS2, ARHGAP35, GSC2, GTF2F1, GTF2I, GTF3A, BRF1, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, H2AFZ, HBE1, HCK, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIF1A, HIP1, HIVEP2, ZBTB48, HLF, HLX, HMGN1, HMGA1, NR4A1, HMX1, HMX2, FOXA2, HNF4G, ONECUT1, HNRNPD, HOXC10, HOXC11, HOXD3, HOXD8, HOXD9, HOXD10, HOXD11, HOXD12, PRMT2, HES1, HSF4, HSPA8, ICAM1, IFI16, SP110, IFNA2, IFNG, IGBP1, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL1B, IL10, IL17A, ILF3, ILK, ING2, INS, INSIG1, IRAK1, IRAK2, IRF1, IRF2, IRF5, ISL1, ITGA3, JARID2, JUN, JUND, KIT, KRAS, AFF3, ABLIM1, LMO1, LTF, LUM, EPCAM, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MEOX2, CIITA, ATXN3, AFF1, FOXO4, CITED1, PPP1R12A, TONSL, CNOT2, NRL, YBX1, NTF3, NTRK1, NTRK3, OGG1, SIX6, ORC1, ORC2, OTX1, OTX2, OVOL1, P2RY1, PA2G4, PCSK6, SERPINE1, PAM, PARK2, PAWR, PAX3, PAX4, PAX9, PBX1, PCK1, PCNA, CHMP1A, PDE8A, PER1, PEX14, PF4, PFDN1, ATP8B1, PFN1, PGR, PHF2, PIM1, PRRX1, PPID, PPM1A, PPP1R8, PPP2R1A, PPP3R1, PRKAA1, PRKAR1A, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK8, EIF2AK2, RELN, PSEN1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PTAFR, PTEN, PTGIS, PTHLH, PURA, RAD21, RAF1, RAN, RARA, RARB, RB1, RBL1, RBL2, RELB, DPF2, REST, RFX1, RFX2, RFX3, RFXAP, RLF, RNF6, RPS3, RPS6KA1, RREB1, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A12, SALL1, SATB1, XCL1, TRAPPC2, SET, SFPQ, SFRP4, SFRP5, SFSWAP, SGK1, SIM2, SIX1, SIX3, SLC9A1, SLC11A1, SMARCA1, SMARCA2, SMARCA4, SMARCC2, SMARCD1, SMARCD3, SMARCE1, SNAI1, SNAPC1, SNAPC2, SNAPC3, SNCA, SOD2, SOX1, SOX2, SOX3, SOX9, SOX10, SOX11, SOX12, SP1, SP4, SP100, SPIB, SREBF1, SRF, SRY, TRIM21, SSRP1, STAT1, STAT2, STAT3, STAT4, STAT5B, STAT6, SUPT4H1, SUV39H1, TAF2, TAF4B, TAF5, TAF6, TAF7, TAF10, TAF13, TAL1, TAL2, TBL1X, TBP, HNF1A, ZEB1, ZNF354A, NR2F1, NR2F2, KLF10, TMF1, TMPO, TNFAIP3, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TSC2, TSG101, TTF1, TULP3, TWIST1, TNFSF4, TNFRSF4, TYMS, UBB, UBE2D2, UBE2L3, UBE3A, SUMO1, UBTF, UCN, UCP1, SCGB1A1, NR1H2, USF1, VAV1, WFS1, WHSC1, WNT1, WNT2, WNT11, XRCC5, YY1, ZFP36, ZFP37, ZFPL1, ZIC1, ZIC2, ZNF3, ZNF711, ZNF7, ZNF8, CNBP, ZNF708, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZSCAN21, ZNF41, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF91, ZNF99, ZNF124, ZNF132, ZNF136, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF217, ZNF223, ZNF224, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, ZXDA, PRDM2, CSDE1, PAX8, FZD5, BRPF1, ARHGEF5, ZNF212, BRD3, CSRP3, FOSL1, FGF23, HMGA2, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, USP9Y, HIST1H4I, PICALM, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, CUL3, CUL2, FOXN1, KLF11, SMARCA5, OGT, ITGA8, IKBKG, IKBKAP, HAT1, GAS7, CBX4, CAMK1, PIR, BLZF1, KHSRP, STK16, RGS20, RUVBL1, KLF7, CDK13, RFXANK, TP63, CHRD, DYNLL1, TRADD, EDF1, URI1, EED, RIPK1, RIPK2, TRIM24, SAP30, HESX1, CFLAR, HDAC3, TSC22D1, KAT2B, PER3, TAX1BP1, BUD31, CPNE1, PHOX2B, HIST1H3F, HIST1H2AG, USP13, RPS6KA4, TNFSF18, TAF1C, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, USP2, PDLIM1, RQCD1, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, SLC33A1, AURKB, CCPG1, ITGB1BP1, ZNF235, KLF4, COPS2, TRIP11, HMGN3, CNOT8, CER1, CIAO1, RECQL5, ZRANB2, HAND1, ZNF264, EIF2AK3, FHL5, ONECUT2, LITAF, TBPL1, ZNF254, CLOCK, SOX13, RBM39, RNF14, ABCG1, ZNF592, CTR9, ZNF516, KDM4A, VGLL4, BZW1, ST18, ZNF646, SETD1A, HDAC4, ZFYVE16, BCLAF1, MAML1, KEAP1, TSC22D2, RB1CC1, ARHGEF11, ZEB2, ZBTB24, ZNF518A, SETDB1, SUPT7L, RNF10, ZBTB5, NR1I3, NR1H4, NR1D2, RBX1, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, PREB, ZNF263, ZNF256, SORBS3, RNF41, TRIM13, OLIG2, TRIB1, ZNF443, DENND4A, IRX5, RAMP3, FSTL3, SAP18, APBB3, TNIP1, IKZF1, TRIM22, HMG20B, HMG20A, KLF2, CITED2, PIAS3, RAPGEF3, RBM14, PPIE, MAD2L2, SLC30A9, TRIM38, CREB3, CARM1, SEMA4D, ZNF211, DEAF1, SIVA1, ERN2, USP16, ERLIN1, HEXIM1, RBCK1, ARID3B, TRIM16, TXNIP, DMRT2, KHDRBS1, CTCF, TBR1, STAG2, RAI1, PHTF1, ZMYND11, ZBTB6, ZNF234, ZNF266, ZNF273, ZNF275, RUVBL2, ARID5A, MALT1, BRD8, PRDX3, YWHAQ, ASCC3, COPS5, CCDC85B, VAX1, GTF2A1L, PIM2, WWP1, WWP2, SOX30, WDR5, PRDM7, PRDM5, KAT7, ERLIN2, SOX21, PSIP1, STRAP, ZNF277, SUPT16H, CHEK2, DDX20 |
2045 | GO:0048523 | 0.00 | 1.33 | 234.22 | 275 | 688 | negative regulation of cellular process | A2M, ACACB, ACADL, ACADVL, ACVR2B, ADAM10, ADRA1B, AEBP1, APLP1, APLP2, ASS1, RERE, ATP1A1, ATR, BACH1, BCL7A, BMI1, BMP6, KLF5, SERPING1, C3, CASQ1, SERPINH1, CCNC, CCNT1, CD36, CDA, CDH1, CDX2, CDX4, CHD4, CIRBP, CCR5, COL1A1, COL6A3, CRYM, CST6, CYBA, DAPK3, DDX5, DIAPH1, DLG2, HBEGF, E2F6, EIF2S1, SERPINB1, EN1, EP300, EPRS, ERF, ETV6, GALR1, GAPDH, GATA4, NR6A1, GDF9, GFRA2, GNAQ, GOLGA2, XCR1, GRB7, GRM8, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, H2AFZ, HBE1, SERPIND1, HDGF, HMX1, HNRNPD, HOXD8, HOXD9, HRC, HSF4, HTR2C, IDE, EIF3E, IRAK2, IRF2, ITIH1, ITIH3, ITIH4, ITPR2, JUND, KNG1, KIF25, LIMK1, LMO1, CAPRIN1, CIITA, TONSL, ORC2, OVGP1, PEBP1, PAX3, PAX9, SERPINA5, CHMP1A, PDE4D, ATP8B1, PI3, SERPINA4, SERPINB5, SERPINB8, SERPINB10, SERPINI2, PRRX1, PPID, PPP1R1A, PRKAR1B, PRKAR2A, PRKAR2B, PRPSAP1, PTGIS, PURA, PZP, RAN, RANBP2, RBL1, RBM4, RELB, RENBP, UPF1, RFX3, RPS3, RREB1, RYR1, RYR2, RYR3, S100A1, SATB1, SERPINB4, SFPQ, SRSF4, SRSF7, SFSWAP, SIM2, SMARCC2, SMARCE1, SNRNP70, SRP9, SRY, STAT6, SUPT4H1, SUV39H1, TAL1, SERPINA7, TBL1X, TBP, NR2F1, NR2C1, TRO, TRPC1, TTF1, UBTF, USP4, VTN, WHSC1, YY1, ZFP36, ZIC2, ZNF8, ZNF24, ZNF91, ZNF136, ZNF148, ZNF154, ZNF157, ZNF174, ZNF177, ZNF189, ZNF217, ZNF224, AKAP1, NRIP1, USP9X, KDM5C, FZD4, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, SOX14, UXT, ZNF282, DYRK2, HAT1, EIF4EBP3, AKR1C3, DYNLL1, SRSF9, SERPINB7, EED, SAP30, HESX1, PER3, EIF2B3, EIF2B5, HIST1H3F, HIST1H2AG, TRPA1, TAF1C, TAF1B, TAF1A, RNF8, UBA3, USP14, USP2, COPS2, RECQL5, HAND1, QKI, AKAP6, ZNF254, EI24, GABBR2, DHX34, ST18, BCLAF1, RNF40, KEAP1, ZEB2, PPP1R26, SETDB1, FIG4, NR1I3, NR1D2, CASP8AP2, ACOT8, ZBTB33, ZNF263, FARP1, ZNF256, SORBS3, PRG4, RAMP3, SAP18, IKZF1, TRIM22, ABCA7, HMG20B, PRG3, PIAS3, CD2BP2, TACC3, CRTAP, DEAF1, SIVA1, ERN2, ERLIN1, TXNIP, IGF2BP3, CTCF, CERS1, GIPC1, ZNF234, SPINT3, ARID5A, USP19, RNPS1, OS9, SPINK5, WWP1, WWP2, PRDM5, ERLIN2 |
2046 | GO:0007010 | 0.00 | 1.33 | 158.49 | 186 | 428 | cytoskeleton organization | ABL1, ABL2, ACTG1, ACTN1, ADRA2A, ANG, ANXA1, BIRC5, ARHGAP4, ARHGDIB, BBS2, BCL2, BCR, BICD1, BRCA2, BST2, CAPN6, CASQ1, CASQ2, CDC42, CDK2, CENPA, CENPE, CHD3, CHD4, CHEK1, CNN1, CNN2, CNN3, CNP, CSF1R, CSNK1D, CTNNA1, CTSV, CXADR, CYLD, DAPK3, GADD45A, DIAPH1, DIAPH2, DNAH5, DYNC1H1, DPYSL3, EFNA5, EML1, EMP2, EPB41, EPB41L2, EPHA5, EYA1, FGD1, FGF7, GAPDH, GHSR, GOLGA2, CXCL1, HRG, ILK, INPPL1, INSRR, ITGB1, KISS1, KIT, KRAS, KRT13, KRT19, LAMA5, ABLIM1, LLGL2, MAP6, MYO1B, PPP1R12A, NUMA1, PALM, PAM, PAWR, PCM1, CHMP1A, PEX14, PPP2R1A, PRKAR1A, PRKCI, PRKCZ, PYY, PTEN, PTGER4, PTK2, PTPN1, RAB13, RAC2, RAC3, RALA, RAN, RAP2A, S100A8, S100A9, SDCBP, SHC1, STIL, SIPA1, SLC9A1, SLC16A1, FSCN1, SON, SOX9, SPAG1, SPAG4, SRF, SVIL, TACC1, CNTN2, TBCE, DYNLT1, TNNT2, HSP90B1, TSC1, TTK, TUBG1, CLRN1, UVRAG, CORO2A, WEE1, XRCC2, ZNF207, ALMS1, CSRP3, GAN, SMC1A, UXT, CUL3, SORBS2, CNTNAP1, GAS7, CDC14A, DYNLL1, RAB11A, CFLAR, HDAC3, LATS1, SMC3, ZW10, ZMYM6, PDLIM7, S1PR2, TRIP10, TAOK2, SLC9A3R1, KIF3B, NRXN1, NRXN2, CRIPT, BCAR1, CDC42BPB, CEP135, CROCC, SEMA3E, SLK, KIAA0101, CKAP5, CUL7, ARHGEF11, ARHGEF17, ELMO1, KIAA0753, FARP2, CEP350, ABI1, PDCD6IP, RANBP9, KIF20A, AKAP9, SPRY1, TRDN, CORO2B, MAD2L2, TACC3, CAP1, TACC2, SORBS1, DCTN6, KIF2C, TPPP, CAPN10, KPTN, CHEK2, FZD10 |
2047 | GO:0051252 | 0.00 | 1.32 | 728.94 | 831 | 1949 | regulation of RNA metabolic process | ABCA2, ABL1, ACTL6A, ACTN1, ACVR1, ACVR2A, ACVR2B, ACVRL1, ADRB2, AEBP1, JAG1, AGTR2, NR0B1, AKT2, ALK, ALX3, ANXA3, BIRC2, XIAP, BIRC5, APP, PHOX2A, ARNT, ARNTL, ASCL1, ASCL2, ATF4, RERE, ATOH1, ATRX, BACH1, BARD1, CCND1, BCL3, BCL7A, PRDM1, BMI1, BMP1, BMP3, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, BRCA1, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTG1, BTK, CAMK4, CAMK2A, CAT, RUNX2, RUNX1T1, CBFB, CBL, CCNB1, CCNC, CCNE1, CCNH, CCNT1, CCNT2, CD3D, CD28, CD80, CD86, TNFSF8, CD36, CD38, CD81, CDK11B, CDC5L, CDH1, CDK2, CDK8, CDK9, CDKN2A, CDX1, CDX2, CDX4, CEBPE, CENPB, CENPF, CGA, CHD1, CHD2, CHD3, CHD4, CHEK1, CHUK, CLU, CLK1, CLK3, COL1A1, CREB1, ATF2, CREBL2, CRX, CRY1, CRY2, CRYM, CSNK2A1, CSNK2A2, CTH, CTNND2, CYLD, DAB2, DGKQ, DAPK3, DCN, DDIT3, DDX1, DDX5, DHFR, DLX5, DLX6, DNM2, DNMT1, DNMT3B, DRD3, ARID3A, RCAN1, TSC22D3, DYRK1A, E2F2, E2F4, E2F6, E4F1, EBF1, ECM1, EDA, S1PR1, EFNA1, EGR2, EGR3, EGR4, ELAVL2, ELK1, EMX1, EMX2, EN1, EP300, EPHA5, ERBB2, EREG, EYA4, ERCC3, ERCC6, ERF, ERG, ERN1, ESR1, ESRRG, ETS1, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA1, EYA2, EYA3, EZH1, F2R, F2RL1, FBN1, EFEMP1, FGF4, FGF7, FGFR3, FLI1, AFF2, FRK, FSHB, NR5A2, NR5A1, FZD2, GABPA, GALR1, GAS6, GATA4, GATA6, GCG, KAT2A, NR6A1, GDF9, GFI1, GPC3, GPS2, ARHGAP35, GSC2, GTF2F1, GTF2I, GTF3A, BRF1, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, H2AFZ, HBE1, HCK, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIF1A, HIP1, HIVEP2, ZBTB48, HLF, HLX, HMGN1, HMGA1, NR4A1, HMX1, HMX2, FOXA2, HNF4G, ONECUT1, HNRNPD, HOXC10, HOXC11, HOXD3, HOXD8, HOXD9, HOXD10, HOXD11, HOXD12, PRMT2, HES1, HSF4, HSPA8, ICAM1, IFI16, SP110, IFNA2, IFNG, IGBP1, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL1B, IL10, IL17A, ILF3, ILK, ING2, INS, INSIG1, IRAK1, IRAK2, IRF1, IRF2, IRF5, ISL1, ITGA3, JARID2, JUN, JUND, KIT, KRAS, AFF3, ABLIM1, LMO1, LTF, LUM, EPCAM, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MEOX2, CIITA, ATXN3, AFF1, FOXO4, CITED1, PPP1R12A, TONSL, CNOT2, NRL, YBX1, NTF3, NTRK1, NTRK3, OAS3, OGG1, SIX6, ORC1, ORC2, OTX1, OTX2, OVOL1, P2RY1, PA2G4, PCSK6, SERPINE1, PAM, PARK2, PAWR, PAX3, PAX4, PAX9, PBX1, PCK1, PCNA, CHMP1A, PDE8A, PER1, PEX14, PF4, PFDN1, ATP8B1, PFN1, PGR, PHF2, PIM1, PRRX1, PPID, PPM1A, PPP1R8, PPP2R1A, PPP3R1, PRKAA1, PRKAR1A, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK8, EIF2AK2, RELN, PSEN1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PTAFR, PTEN, PTGIS, PTHLH, PURA, RAD21, RAF1, RAN, RARA, RARB, RB1, RBL1, RBL2, RBM4, RELB, UPF1, DPF2, REST, RFX1, RFX2, RFX3, RFXAP, RLF, RNF6, RPS3, RPS6KA1, RREB1, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A12, SALL1, SATB1, XCL1, TRAPPC2, SET, SFPQ, SFRP4, SFRP5, SRSF4, SRSF6, SRSF7, SFSWAP, SGK1, SIM2, SIX1, SIX3, SLC9A1, SLC11A1, SMARCA1, SMARCA2, SMARCA4, SMARCC2, SMARCD1, SMARCD3, SMARCE1, SNAI1, SNAPC1, SNAPC2, SNAPC3, SNCA, SNRNP70, SOD2, SON, SOX1, SOX2, SOX3, SOX9, SOX10, SOX11, SOX12, SP1, SP4, SP100, SPIB, SREBF1, SRF, SRPK2, SRY, TRIM21, SSRP1, STAT1, STAT2, STAT3, STAT4, STAT5B, STAT6, SUPT4H1, SUPV3L1, SUV39H1, TAF2, TAF4B, TAF5, TAF6, TAF7, TAF10, TAF13, TAL1, TAL2, TBL1X, TBP, HNF1A, ZEB1, ZNF354A, NR2F1, NR2F2, KLF10, TMF1, TMPO, TNFAIP3, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TSC2, TSG101, TTF1, TULP3, TWIST1, TNFSF4, TNFRSF4, TYMS, UBB, UBE2D2, UBE2L3, UBE3A, SUMO1, UBTF, UCN, UCP1, SCGB1A1, NR1H2, USF1, VAV1, WFS1, WHSC1, WNT1, WNT2, WNT11, XRCC5, YY1, ZFP36, ZFP37, ZFPL1, ZIC1, ZIC2, ZNF3, ZNF711, ZNF7, ZNF8, CNBP, ZNF708, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZSCAN21, ZNF41, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF91, ZNF99, ZNF124, ZNF132, ZNF136, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF217, ZNF223, ZNF224, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, ZXDA, PRDM2, CSDE1, PAX8, FZD5, BRPF1, ARHGEF5, ZNF212, BRD3, CSRP3, FOSL1, FGF23, HMGA2, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, USP9Y, HIST1H4I, PICALM, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, CUL3, CUL2, FOXN1, KLF11, SMARCA5, OGT, ITGA8, IKBKG, IKBKAP, HAT1, GAS7, CBX4, CAMK1, PIR, BLZF1, KHSRP, STK16, RGS20, RUVBL1, KLF7, CDK13, RFXANK, TP63, CHRD, DYNLL1, SRSF9, TRADD, EDF1, URI1, EED, RIPK1, RIPK2, TRIM24, SAP30, HESX1, CFLAR, HDAC3, TSC22D1, KAT2B, PER3, TAX1BP1, BUD31, CPNE1, PHOX2B, HIST1H3F, HIST1H2AG, USP13, RPS6KA4, TNFSF18, TAF1C, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, USP2, RGN, PDLIM1, RQCD1, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, SLC33A1, AURKB, CCPG1, ITGB1BP1, ZNF235, KLF4, COPS2, TRIP11, HMGN3, CNOT8, CER1, CIAO1, RECQL5, ZRANB2, HAND1, ZNF264, EIF2AK3, FHL5, ONECUT2, LITAF, TBPL1, ZNF254, GTPBP1, CLOCK, SOX13, RBM39, RNF14, ABCG1, ZNF592, CTR9, ZNF516, KDM4A, VGLL4, BZW1, DHX34, ST18, ZNF646, SETD1A, HDAC4, ZFYVE16, BCLAF1, MAML1, RNF40, KEAP1, TSC22D2, RB1CC1, ARHGEF11, ZEB2, ZBTB24, ZNF518A, SETDB1, SUPT7L, RNF10, ZBTB5, RBM8A, NR1I3, NR1H4, NR1D2, RBX1, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, PREB, ZNF263, ZNF256, SORBS3, RNF41, TRIM13, OLIG2, TRIB1, ZNF443, DENND4A, SF3B4, IRX5, RAMP3, FSTL3, SAP18, APBB3, TNIP1, IKZF1, TRIM22, HMG20B, HMG20A, KLF2, CITED2, PIAS3, IFITM3, RAPGEF3, RBM14, PPIE, MAD2L2, SLC30A9, TRIM38, CREB3, CARM1, SEMA4D, ZNF211, DEAF1, SIVA1, ERN2, USP16, ERLIN1, HEXIM1, RBCK1, ARID3B, TRIM16, TXNIP, DMRT2, KHDRBS1, CTCF, TBR1, STAG2, RAI1, PHTF1, AHCYL1, ZMYND11, ZBTB6, ZNF234, ZNF266, ZNF273, ZNF275, RUVBL2, ARID5A, MALT1, BRD8, PAPOLA, RNPS1, PRDX3, YWHAQ, ASCC3, COPS5, CCDC85B, VAX1, GTF2A1L, PIM2, WWP1, WWP2, SOX30, WDR5, PRDM7, PRDM5, KAT7, ERLIN2, SOX21, PSIP1, STRAP, ZNF277, SUPT16H, CHEK2, DDX20 |
2048 | GO:0044711 | 0.00 | 1.32 | 173.26 | 203 | 476 | single-organism biosynthetic process | ABCA1, ADCY3, ADCY5, ADCY6, ADCY9, ADRA2A, ADRB2, ADSL, ADSS, NR0B1, AK1, AK2, AK4, AKT2, ALDH3A2, AMPD1, AMPD2, ANG, APLP1, ARF1, ATM, ATP1A1, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, ATP5O, ATR, AVPR2, C3, CALCR, CALM1, CALM3, CCT6A, CDA, CREB1, CREBL2, CRH, CSNK1G2, CTPS1, DKC1, DRD3, DRD5, DTYMK, DUT, TYMP, LPAR1, EDNRA, EEF2, EIF5A, ESD, ACSL1, ACSL4, FDXR, FSHR, NR5A1, FUT8, B4GALNT1, GALR1, GHRH, GHRHR, GLB1, GLP1R, GMDS, GNAL, GNAS, GPLD1, GRM8, GSTM1, GSTM2, GSTZ1, GUCA1A, GUCA1B, GUCA2A, GUCA2B, GUCY1B3, GUCY2C, GUCY2F, GYS2, GUCY2D, HARS, HEXB, HNRNPC, HSD11B1, HTR2C, IDH1, IGF2, IMPDH1, IMPDH2, INPP4A, INPPL1, INSL3, MAT2A, MGAT2, NTRK1, NTRK2, OAS2, P2RX1, P2RX7, P2RY11, PALM, PBX1, PDC, PEX7, PFAS, PGM3, PHKG1, PIGC, PIK3C2B, PIK3C3, PIK3CB, PI4KA, PIP4K2A, PRKCD, PRKD1, PRKCQ, PRPSAP1, PTEN, PTHLH, RAF1, RCVRN, REV3L, RRM1, RRM2, ST6GAL1, ST8SIA1, SLC2A1, UAP1, SRD5A1, STAT3, TAZ, TNFRSF1A, CCT3, TUFM, TYMS, UBB, UBA7, UPP1, VIP, VIPR2, WFS1, TRIM25, EPM2A, PDHX, PIP5K1B, NSMAF, DYRK2, CUL4A, PIK3R3, AGPS, MAPKAPK5, PDXK, HSD17B6, DGAT1, B3GALT2, SUCLG1, DPM2, INPP4B, SYNJ1, CPNE1, PAPSS2, PAPSS1, AURKB, VAPB, AKAP6, PIGL, GAL3ST1, TBPL1, MPDU1, ATP5J2, GABBR2, AKAP12, GUCA1C, KIAA0101, PTDSS1, EPM2AIP1, FIG4, XYLB, RBX1, GNE, PIGK, COL4A3BP, RAD50, CALCRL, RAMP2, CDIPT, MAD2L2, ATP5H, CAP1, SLC35A1, CCT7, CCT4, CCT2, SORBS1, ATP5L, CERS1, SLC26A1, ACOT2, DDX20 |
2049 | GO:0009966 | 0.02 | 1.32 | 84.72 | 100 | 241 | regulation of signal transduction | A2M, ABCA1, BIRC5, ARF6, ARHGDIB, BCL3, BCR, CNGA1, RCAN1, EP300, EPHA7, EPHB1, FGD1, GAS1, GDI1, GDI2, GFRA2, GNAI1, GNAT1, GNB1, GNGT1, GUCA1A, GUCA1B, GUCY2F, GUCY2D, PRMT2, HSP90AB1, IFNA5, IFNA13, IFNA17, IFNA21, IFNGR1, IFNW1, IRF1, LLGL2, OTX2, PCSK6, PRDX1, PDE4A, PPP1R2, PRCP, PTPN13, RAC2, RAC3, RAP1GAP, RAP2A, RCVRN, RDX, RNF6, RS1, SAG, SDF2, SIPA1, STAT2, STYX, SYP, ZEB1, DYNLT1, TSG101, SUMO1, VAV1, VRK2, ZIC1, OGT, TRIM24, INPP4B, TAX1BP1, KALRN, RGN, ARHGEF1, CYTH3, NREP, TRIP10, ARHGAP29, ARHGEF6, RNF14, GUCA1C, RALGPS1, TTI1, IFT140, ARHGAP32, ARHGEF11, ARHGEF17, FARP2, RHOBTB1, ARHGAP25, FARP1, RNF41, RCAN2, RAMP2, RAMP3, SLC9A6, CARM1, ARFGEF2, PDE10A, USP20, COPS5, RCAN3, CDC37, AKAP13 |
2050 | GO:0051301 | 0.01 | 1.31 | 115.42 | 135 | 310 | cell division | ANXA11, ARF6, ATM, ATRX, BBS4, CCND1, BCL2L1, BMP4, BRCA2, ZFP36L2, BUB1B, CALM1, CALM3, CAV2, CCNB1, CCND3, CCNE1, CCNF, CCNG1, CCNG2, CCNT1, CCNT2, CDC20, CDC25A, CDC25C, CDC27, CDK2, CDK3, CDK4, CDK6, CDKN2A, CENPE, CENPF, CETN1, CHEK1, CKS1B, CKS2, CSNK2A1, CSNK2A2, DAPK3, DIAPH2, DUSP1, E4F1, ETV5, FGFR3, GNAI1, GOLGA2, SFN, GPR3, ING2, KIT, LLGL2, SEPT2, NUMA1, CHMP1A, PDE3A, CDK14, PIK3C3, PIK3CB, SEPT5, PRKAR1A, RAD1, RAD21, RALA, RAN, RPS3, SON, TACC1, DYNLT3, DYNLT1, TOP1, TOP2A, TSG101, TTK, UVRAG, VRK1, WEE1, ZNF207, TUBA1A, HMGA2, USP9X, SMC1A, FZD7, CDC14A, RUVBL1, CDK13, TP63, NUMB, CDC23, RAB11A, CDC123, CDC16, RNF8, USP8, LATS1, SMC3, CCNB2, CCNE2, CTDP1, ARHGEF2, ZW10, NUMBL, RECQL5, BCAR1, MAD2L1BP, CKAP5, IST1, CUL7, ARHGEF11, KLHL21, DCLRE1A, PDCD6IP, TOM1L1, SMC4, ACTR2, KIF20A, KATNB1, ANAPC10, MAD2L2, SSSCA1, USP16, STAMBP, TXNIP, USP39, STAG2, ARPP19, SEPT9, RAB10, JTB, TXNL4A, KIF2C, RAB35, PAPD7, ZWINT, CHEK2 |
2051 | GO:1901137 | 0.02 | 1.31 | 98.45 | 115 | 267 | carbohydrate derivative biosynthetic process | ABO, PARP4, ARCN1, AREG, ART1, ART3, BCL2, BMPR2, CANX, CD59, CDA, CGA, COPA, CSNK1D, CTSZ, DAD1, DYNC1H1, DYNC1I1, DYNC1I2, DPAGT1, HBEGF, DTYMK, DUT, TYMP, FUT6, FUT8, B4GALNT1, GALNT1, GK2, GLB1, GMDS, GOLGA2, GOLGB1, GRIA1, IL15, INS, KCNE1, LIPC, LMAN1, MAT2A, MGAT2, MGAT3, OAS2, PAWR, PDC, CFP, PGM3, PIGC, PPP6C, PRKAA1, PRKCSH, PSEN1, RAB1A, RPN2, RRM1, RRM2, CCL21, SDF2, TRAPPC2, SEL1L, SHMT1, ST6GAL1, ST8SIA1, SLC2A4, SORD, UAP1, TRAPPC10, TYMS, UGP2, VEGFB, TUSC3, OGT, USO1, DYNLL1, GALNT4, B3GALT2, DPM2, KAT2B, COPB2, COG1, PIGL, GAL3ST1, TBPL1, MPDU1, GOSR1, TMEM59, SEC22B, GOSR2, PTDSS1, XYLB, ACOT8, GNE, PIGK, PREB, CHST4, TNIP1, AKR1A1, TMEM5, ABCA7, SPON1, SEC24B, COG5, SEC23A, SLC35A1, ARFGEF1, YKT6, DCTN6, FUT9, SEC24A, KDELR1, OS9, TMED2, ADAMTS13, ADAMTS5, ADAMTS7 |
2052 | GO:0044265 | 0.00 | 1.30 | 214.27 | 248 | 574 | cellular macromolecule catabolic process | AGXT, BIRC2, ARAF, ARNTL, ATM, BNIP3, BNIP3L, ZFP36L2, BUB1B, CAV3, CBL, CCNB1, CCNF, CD81, CDC20, CDC27, CDK2, CENPF, CLU, CSNK1D, CSNK2A1, CSNK2A2, CTSH, CTSK, CTSV, CTSZ, CYLD, DAB2, DDIT3, DDX6, DUSP1, EIF4A1, EIF4E, EIF4G1, ERN1, ETF1, PTK2B, FAP, FAU, FEN1, GPX1, UBE2K, HNRNPD, DNAJB2, HSP90AB1, IDE, EIF3E, SMAD7, DNAJB9, ATXN3, RPL10A, CNOT2, CNOT4, OAS2, PARK2, PCBP2, PPP1R8, PPP2CB, PPP2R1A, PPP2R2A, PSEN1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB5, PSMC1, PSMC2, PSMC3, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSME1, PSME2, PTEN, PTK2, RAD23B, RB1, RBBP6, RDX, UPF1, RNASE2, RNASE6, RNF6, ABCE1, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, SDCBP, SEL1L, SGTA, SIAH1, SKP1, SUMO3, AURKA, SUPV3L1, TBL1X, TMF1, TNFAIP3, HSP90B1, TSG101, TTC3, TTK, UBB, UBA7, UBE2D2, UBE2H, UBE2L3, UBE3A, SUMO1, USP4, WFS1, WNT1, ZFP36, TRIM25, ZNF207, CSDE1, RNF103, RAB7A, USP5, GAN, CLPP, USP11, USP9X, USP9Y, BAP1, CUL4A, CUL3, CUL2, CUL1, COPS3, PRPF18, KHSRP, RNASET2, CDC23, CTSF, RIPK1, CDC16, HERC2, USP13, RNF8, RPL14, USP14, USP2, USP8, RQCD1, ZW10, AURKB, SOCS6, CNOT8, RPL23, UBE4A, PSMF1, BAG5, GTPBP1, CLOCK, RNF14, RNF7, UBE3C, DHX34, EIF4A3, DLGAP5, RNF40, KEAP1, CUL7, PSMD6, SMG7, KLHL21, RBM8A, USP3, RBX1, KCNE2, HDAC6, PDCD6IP, TOM1L1, RNF41, PSME3, TRIM13, PSMD14, TRIB1, ZMPSTE24, MARCH6, ANAPC10, ARIH2, MAD2L2, TRIM38, RNASEH2A, ERN2, USP16, ERLIN1, RBCK1, YME1L1, GIPC1, USP20, USP19, RNPS1, SEC61B, OS9, WWP1, WWP2, UBE2C, ATE1, GLMN, ERLIN2, ADAMTS7, CHEK2, RPL35 |
2053 | GO:0006470 | 0.05 | 1.30 | 69.57 | 81 | 186 | protein dephosphorylation | ACP1, AGTR2, BCL2, CALM1, CALM3, CDC25A, CDC25C, CRY2, DLG2, DLG3, DUSP1, DUSP4, DUSP5, EYA4, EYA1, EYA2, EYA3, GPLD1, IFNG, IGBP1, ITGA1, SMAD3, PPP1R12A, PAWR, PPM1A, PPM1B, PPP1R2, PPP2CB, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PPP4C, PPP3R1, PPP5C, PPP6C, PRKCD, EIF2AK2, PTEN, PTPN1, PTPN4, PTPN6, PTPN7, PTPN13, PTPRA, PTPRD, PTPRE, PTPRH, PTPRJ, PTPRM, PTPRN, PTPRN2, PTPRR, PTPRS, SBF1, SET, STYX, HSP90B1, TSC1, EPM2A, AKAP1, PPM1D, CDC14B, CDC14A, URI1, RNGTT, RGN, CTDP1, AKAP6, BAG4, DLGAP5, DNAJC6, PPP1R26, NUAK1, FARP1, CTDSPL, CD2BP2, SEMA4D, ARPP19, PTPN21, PTPRT |
2054 | GO:0033036 | 0.00 | 1.28 | 204.22 | 235 | 565 | macromolecule localization | ABAT, ABL1, ACHE, ACVR2B, ADCY5, ADRA2A, NR0B1, ALOX15B, ANG, ANXA5, BIRC5, ARF1, ARL4D, ARF5, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, AZGP1, BLK, BTF3, CANX, CASP1, CASP5, CD3G, CD38, CD58, CENPF, CHRM3, CNR1, CSF1R, DHCR24, DMBT1, DNM2, DNMT3B, DSP, EFNA5, EIF4E, EPHA5, EPS15, ERCC3, F2RL1, FBLN1, FBN1, FGA, FGG, FGR, GCG, GDI2, GHSR, GJA5, GLE1, GLP1R, GLUD1, GLUL, GNAS, GNGT1, GPLD1, GPR27, FFAR1, GRIN2A, HIF1A, HMGCR, FOXA2, AGFG1, DNAJB2, IFNA2, RBPJ, IL1A, IL1RN, IL13, IL17A, ISL1, ITPR1, ITPR2, KCNC2, KCNJ11, KCNS3, KIF5A, LAMP2, LLGL2, LTBP1, MAL, ATXN3, SEPT2, SLC11A2, NRCAM, OXCT1, PAEP, PAM, CHMP1A, PCSK5, PDE3B, PDE4C, PFKFB2, PIK3C3, PPID, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PSEN1, PTGER4, PTPRN, PTPRN2, RAB1A, RAB3B, RAB4A, RAB5A, RAB5B, RAB27B, RABIF, RAB5C, RAF1, UPF1, REST, RFX3, S100A12, S100A13, CX3CL1, SRSF1, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SLC2A1, SLC9A2, SLC15A1, SLC15A2, SLC16A1, SNAP25, STXBP2, STXBP3, ABCC8, SYT5, HNF1A, TRAF2, TRPM2, TSC1, TSG101, TST, TWIST1, TNFSF4, TNFRSF4, USH2A, VEGFC, VIP, WHSC1, YY1, SCG2, ARHGEF5, CUBN, AAAS, PICALM, ITGA8, KHSRP, CADPS, SRSF9, ADAM9, SELENBP1, SYT7, UNC119, ATP6V0D1, SEC22C, RABEP1, IL1RL1, HMGN3, SNAP29, CER1, RAB33A, RAB9A, COG1, QKI, AKAP7, ATG5, STXBP5L, GOSR1, RAB3D, APBA3, ATP6V1G1, SEC22B, VPS26A, GOSR2, CLOCK, RAB36, TRAM2, ACAP1, EIF4A3, CKAP5, IST1, C2CD2L, ZC3H11A, SMG7, SNAP91, RABGAP1L, RBM8A, DOPEY2, PDCD6IP, KIF20A, PREB, CALCRL, DDX39A, IKZF1, TRIM22, COG5, NXF1, ATG7, ARFGEF2, ARFGEF1, TRIM16, EXOC5, IGF2BP3, YKT6, KHDRBS1, TNFSF13B, CCT6B, TRAF3IP2, NUP50, CPLX1, RNPS1, RAB32, WWP2, RAPGEF4, BTN3A1, CAPN10, GLMN, AP4S1, NUDT4 |
2055 | GO:0007264 | 0.03 | 1.28 | 95.32 | 110 | 259 | small GTPase mediated signal transduction | ABL1, ACTB, ACTG1, BIRC5, KLK3, TRIM23, ARF1, ARL4D, ARF5, ARL1, ARL2, BUB1B, KRIT1, CDC20, CDC25C, CDH1, CENPA, CENPE, CENPF, CFTR, CTNNA1, CYBA, CYBB, DIAPH1, DIAPH2, CTTN, CENPI, SFN, KIF5A, KLC1, PPP1R12A, PPP1R12B, NUP98, PIK3C3, RAB1A, RAB3B, RAB4A, RAB5A, RAB5B, RAB6A, RAB13, RAB27A, RAB27B, RABIF, RAB5C, RAN, RANBP2, RANGAP1, RAP1GDS1, RHEB, RPS27, CLIP1, SRF, YWHAZ, RAB7A, RND2, HIST1H4I, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, BCAR3, RAB11A, HIST1H3F, DIRAS3, ZW10, AURKB, RAB33A, RAB9A, RAB3D, RAB36, RAPGEF5, CKAP5, ABI1, SH2D3C, SH2D3A, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, ARL4C, ARL4A, ARFRP1, TNK2, BAIAP2, ARPC1A, RASL10A, RAB10, YWHAQ, RAB32, KIF2C, IFT27, RAB35, RAB31, RAPGEF4, CIT, ZWINT, RABL2B, RABL2A |
2056 | GO:0050789 | 0.00 | 1.25 | 458.76 | 508 | 1475 | regulation of biological process | AAMP, ABCA4, ADORA3, APLNR, AGXT, AK1, ALDH3A1, ALDH1A3, ANXA6, KLK3, ARL4D, ARF5, ARG1, STS, ASNA1, ATP1A3, ATP1A4, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP4A, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, AZGP1, BCHE, BCL2A1, TNFRSF17, HCN2, OPN1SW, DST, BSG, CAPN5, DAGLA, CACNA1B, CACNA2D1, CAPN1, CAPN6, CCNF, CCNG2, CD7, CD9, ENTPD2, CD53, CD58, CD70, CD72, ADGRE5, CD151, CDH6, CDH15, CDK3, CENPA, CFL2, AKR1C4, CHRM3, CHRNB4, CLCN5, CLCN6, CLCN7, CLCNKA, CLCNKB, TPP1, CCR3, CCR8, ACKR2, LTB4R, CNN1, CNN2, COL5A2, COL15A1, COMP, CORT, CLDN3, CPS1, CSH1, CSNK1G3, CTSV, CYBB, CYP24A1, DAD1, DGKA, DGKB, BRINP1, DBI, DCX, DIAPH2, DOK1, DPP6, DTNA, ECM2, S1PR3, EFNA3, EFNA4, EMP3, ERCC5, EXT1, EXT2, F2RL2, FABP6, FANCA, FBLN2, GPC4, FPR3, CENPI, GAST, GAA, GABRA6, GABRE, GABRG1, GABRR1, GABRR2, GAK, GAS2, OPN1MW, GFRA1, GH2, GLRA2, GLS, GLUD1, GLUL, GMDS, GNAT2, GNAZ, GNG10, GNG11, GNGT2, GNRH2, GNRHR, GOT1, GPR1, CCR10, GPR4, GPR15, GPR17, GPR19, LPAR4, GPR26, GRIA1, GRIA4, GRID1, GRN, GRIK3, GRPR, GUCY1B3, GUCY2C, HBA2, HNMT, HPGD, HRH2, HSPA9, HTR3A, IFIT3, IGFALS, IL1RAP, IL10RA, IL12RB2, IL15RA, IMPA1, INPP1, INPP4A, INSL4, INSRR, ISG20, ITGA9, ITGAD, ITGAX, ITGB4, CD82, KCNA1, KCNA3, KCNA4, KCNA10, KCNC1, KCNC2, KCND2, KCND3, KCNE1, KCNH2, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ12, KCNJ13, KCNJ14, KCNJ16, KCNK3, KCNS2, KCNS3, KIF5A, KLRC2, KLRC3, KLC1, KPNA3, KPNA4, KPNA5, KRT18, KRT19, LAMA3, LAMA4, LAMA5, LDHA, LIPC, LMAN1, LTBP2, BCAM, DNAJB9, SCGB2A1, MGAT3, NUBP1, NRTN, NTF4, NTN3, OAS2, OMD, OGN, OMP, OR1D2, OR1F1, OR2C1, OR3A2, P2RY4, P2RY6, PAEP, PAFAH2, PCM1, PCSK5, CDK17, PDE4C, PDE7A, PDGFRL, PDYN, PFDN2, VIT, PIK3C2B, PI4KA, SEPT5, PRCC, PRKCSH, PRKX, PYY, TAS2R38, PTGDR, PTGER1, PTGER2, PTGS1, PTH2R, PTPRD, PTPRM, PTPRN, RAB3B, RAB5B, RAB6A, RAB13, RAB27B, RAB5C, RAD51C, RAD51B, RAD51D, RBP1, RBP2, OPN1LW, PRPH2, REG1A, RGR, RLN1, RIT1, RNASE2, RPL24, RPS3A, RPS6, RPS27, RTN2, S100A6, TSPAN31, CLEC11A, SCN2A, SCN3A, SCN4B, SCN7A, SCN8A, SCNN1B, SCTR, SDC2, SEL1L, SRSF5, SHMT2, ST8SIA1, SLC2A1, SLC5A3, SLC8A3, SLC9A3, SLC16A1, SLC34A1, SLC18A1, SNAP25, SPARC, SPAST, SRMS, TROVE2, SSR1, SSTR2, STAU1, STC1, SULT1E1, STRN, STXBP3, SULT1A3, ABCC8, SURF4, SVIL, SYN1, SYT5, TACC1, DYNLT3, TSPAN7, TMPRSS2, TNNC2, TOP2B, TRHR, TRPC4, TSHB, TTC3, TUB, TUFT1, TULP1, UBA7, UBE2E2, UPK1B, USH2A, VIPR1, CORO2A, WEE1, XPA, XPC, XRCC2, RNF112, IL1R2, KCNAB1, TUSC3, CLTCL1, SYN3, EPX, FZD9, OR1A1, OR1D5, OR1E1, OR1E2, OR1G1, OR3A3, SPARCL1, SOAT2, DOC2A, SORBS2, PPM1D, COPS3, API5, CDC14A, OR6A2, UNC5C, SSNA1, DCHS1, KCNK5, STX10, DGAT1, CTNNAL1, TNFRSF10D, PEX11A, IL18RAP, CDKL1, NRP2, HCAR3, SYNJ1, BAIAP3, CDKL2, RHBDL1, TAAR5, DOK2, SYT7, ANGPTL1, USP8, ATP6V0D1, CCNB2, ATG12, SYNGR3, FIBP, RASSF9, REPS2, SLC24A1, KCNAB3, ZMYM6, GPR50, NUMBL, PDLIM7, STK17B, BCL7B, TAAR2, GLP2R, RAB9A, KIF3B, NRXN2, CRIPT, KCNK6, AKAP7, ADAMTS1, GOSR1, TP53I11, RAB3D, ATP6V1G1, GOSR2, CDC42BPB, MAD2L1BP, CYTIP, RAB36, GNA14, CLCA2, SDC3, FRMPD4, KIAA0101, SNX17, CKAP5, TATDN2, SPOCK2, CUL7, DNAJC6, C2CD5, KIAA0319, SNAP91, FIG4, KLHL21, RBM19, FAM20B, P2RY14, DLEC1, KCNE3, ABCC9, GPC6, COL4A3BP, TSPAN2, TSPAN1, ARL4C, ARL4A, PDIA6, ARFRP1, DHRS2, NUTF2, KCNMB2, AKAP8, SIGMAR1, SPEG, KATNB1, ATP8A1, PGRMC2, IFI30, GPNMB, TACC3, PPIH, PROCR, TACC2, IFITM2, PDPN, RASL10A, CXCR6, CGRRF1, EBP, RRH, RBBP9, CHL1, OR5I1, CCR9, GJB6, CPLX2, CPLX1, PROKR1, GPR83, RAB10, SEC61B, PDIA5, FERMT2, RAB32, KIF2C, KDELR3, IFT27, RAB35, RAB31, STON1, UPK1A, ABHD2, RER1, ADAMTS13, CIT, PTPRT, ZWINT, CAPN10, IL1RAPL1, RABL2B, RABL2A, NUDT4, WDHD1, ADAMTS7, RASSF8, SEC63 |
2057 | GO:0009058 | 0.00 | 1.25 | 582.67 | 650 | 1688 | biosynthetic process | AARS, ABCA2, ABL1, ABO, ACO1, ACTL6A, ACTN1, ACVR2B, PARP4, AEBP1, ALDH2, ALX3, BIRC2, XIAP, BIRC5, ARCN1, ART1, ART3, ASCL2, CCND1, BCL2, BCL7A, PRDM1, BMI1, BMP1, BMP8B, ZFP36L2, KLF9, BTF3, BTG1, DAGLA, CACNA1A, CANX, RUNX1T1, CBL, CD36, CD59, CDK11B, CDC5L, CDC25A, CDC25C, CDKN1A, CENPB, CENPF, CHD2, CHD3, CHD4, CKM, COMT, COPA, COX4I1, COX5B, COX6A1, COX6B1, COX7C, COX8A, CRY2, CRYM, CSNK1D, CSNK2A1, CSNK2A2, CSTF3, CTNND2, CTSZ, CYBB, CYLD, DAD1, DGKQ, DAPK3, DBH, DDX1, DDX6, DIO2, DIO3, DLX6, DYNC1H1, DYNC1I1, DYNC1I2, DNMT1, DNMT3B, DNTT, RCAN1, TSC22D3, HBEGF, DUSP1, E2F2, E2F6, E4F1, ECM1, EEF1A2, EEF1B2, EFNA1, EGR3, EGR4, EIF1AX, EIF2S1, EIF2B1, EIF2S3, EIF4A1, EIF4E, EIF4EBP1, EIF4G1, EIF4G2, EIF5, ELAVL2, EMX1, EMX2, EPRS, EYA4, ERF, ERG, ERN1, ETF1, ETV3, EWSR1, EYA2, EYA3, FAU, FBN1, EFEMP1, FGFR3, FRK, FUT6, GAD2, GALNT1, GAS6, GDF9, GHSR, GK2, GOLGB1, SFN, FFAR3, GPS2, GPX2, GRB7, GRIA1, ARHGAP35, GSC2, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, HBE1, HCK, HDGF, HIC1, HIP1, HIVEP2, ZBTB48, HLF, HLX, HMX1, HMX2, HOXC10, HOXD3, HOXD11, HOXD12, HSPA8, SP110, IGFBP5, IL1RAP, IL18, INHA, EIF3E, ITGA3, ITGAV, JARID2, KCNE1, KCNK2, AFF3, LMAN1, CAPRIN1, SMAD6, MAZ, MGAT3, ATXN3, NUBP1, DRG1, RPL10A, TONSL, CNOT2, NTRK3, NUP88, NUP98, OAZ1, OAZ2, OGG1, ORC1, ORC2, ORC4, ORC5, OVOL1, PA2G4, PCSK6, PRDX1, PAM, PAX4, CHMP1A, PCSK5, PDE8A, PEX14, CFP, PFDN1, ATP8B1, PFN1, PGGT1B, PIM1, PPID, PPM1B, PPP1R8, PPP2R1A, PPP5C, PPP6C, PRG2, PRKAR1A, PRKCSH, MAPK8, PTMA, PTMS, RAD1, PURA, PYGL, QDPR, RAB1A, RAD51, RBBP6, RBL2, RBM4, RBMS1, DPF2, RFX1, RFX2, RGS2, RGS12, RHEB, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL36AL, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, RYR2, S100A1, S100A11, SATB1, XCL1, SDF2, TRAPPC2, SEL1L, SET, SETMAR, SFPQ, SFRP4, SFRP5, SRSF1, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SFSWAP, SFTPD, SGK1, SIM2, SLC2A4, SLC22A2, SMARCE1, SMS, SNAPC1, SNAPC2, SNAPC3, SNRPE, SNRPF, SOD2, SOX3, SP4, SPIB, SRP9, SRP14, SRP19, SRP68, TROVE2, SSR1, STAT2, SUV39H1, TAF4B, TAF5, TAF6, TAF10, TAF13, TAL2, TARS, TAT, ZNF354A, KLF10, TRAPPC10, TMF1, TMPO, TNFAIP3, TOP1, NR2C1, TRIP6, TSC1, TSG101, TTF1, TULP3, TNFSF4, TNFRSF4, U2AF1, UBE2D2, UBE2L3, SUMO1, UCP1, SCGB1A1, UGT2B4, UGT2B7, VAV1, VEGFB, EIF4H, WHSC1, XRCC5, YWHAZ, ZFP36, ZFP37, ZFPL1, ZNF3, ZNF7, ZNF8, ZNF708, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZNF41, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF91, ZNF99, ZNF124, ZNF132, ZNF136, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF217, ZNF223, ZNF224, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, PRDM2, CSDE1, AIMP2, ZNF212, TUSC3, BRD3, NUP214, SLC25A16, AAAS, CDK2AP1, ANP32A, ZNF239, DPF1, CHAF1B, USP9X, KDM5C, USP9Y, HIST1H4I, FZD6, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, CUL3, CUL2, FOXN1, KLF11, SMARCA5, IKBKAP, HAT1, GAS7, CBX4, PIR, BLZF1, DENR, KHSRP, RGS20, RUVBL1, USO1, CDK13, EIF4EBP3, CHRD, DDX3Y, DYNLL1, EIF3G, EIF3J, EIF4G3, SRSF9, GALNT4, URI1, EED, RNGTT, SAP30, HESX1, TSC22D1, PER3, CDC123, TAX1BP1, EIF2B3, EIF2B2, EIF2S2, HIST1H3F, HIST1H2AG, USP13, TAF1C, TAF1B, TAF1A, RNF8, UBA3, RPL14, EIF1AY, USP2, PDLIM1, RQCD1, CCNE2, ATG12, COX7A2L, DDX21, SLC33A1, COPB2, ZNF235, COPS2, TRIP11, GTF3C5, GTF3C4, GTF3C3, CNOT8, RPL23, CER1, COG1, CIAO1, RECQL5, RECQL4, ZRANB2, ZNF264, ATG5, LITAF, EEF1E1, GOSR1, TMEM59, ZNF254, SEC22B, GTPBP1, GOSR2, SOX13, RBM39, NUP155, ZNF592, EIF5B, KDM4A, VGLL4, NUP93, BZW1, ST18, ZNF646, SETD1A, ZFYVE16, KEAP1, TSC22D2, RB1CC1, ZBTB24, ZNF518A, SETDB1, SUPT7L, ZBTB5, RBM8A, DMTF1, CASP8AP2, ZBTB33, ABCB6, NUBP2, PREB, ZNF263, TRAP1, CHST4, ZNF256, SORBS3, EIF1, OLIG2, PRG4, TRIB1, ZNF443, DENND4A, IRX5, RAMP3, SAP18, EIF1B, APBB3, TMEM5, ABCA7, HMG20B, HMG20A, PIAS3, IFITM3, SPON1, SEC24B, PPIE, COG5, SLC25A17, EIF3M, SEC23A, CARM1, SEMA4D, ZNF211, ATG7, RNASEH2A, SIVA1, ERN2, HEXIM1, IVNS1ABP, TXNIP, SPHAR, IGF2BP3, YKT6, FARS2, RRAGA, DCTN6, FUT9, PHTF1, NUP50, ZMYND11, ZBTB6, ZNF234, ZNF266, ZNF273, SEC24A, ZNF275, ALDH1L1, BRD8, PAPOLA, RNPS1, DBF4, UGT2A1, KDELR1, SEC61B, OS9, TMED2, YWHAQ, ASCC3, CCDC85B, VAX1, GTF2A1L, PAPD7, ADRM1, WWP1, SOX30, HSF2BP, WDR5, ADAMTS13, ADAMTS5, NUPL2, PRDM7, PRDM5, KAT7, SOX21, STRAP, ADAMTS7, ZNF277, RPL35 |
2058 | GO:0044267 | 0.00 | 1.25 | 506.32 | 567 | 1440 | cellular protein metabolic process | ABCA1, ABCA3, ABO, ACADVL, ACP1, ACTB, ACTL6A, ADAM10, ADD1, ADH5, PARP4, AGA, JAG1, AGXT, AMHR2, ANXA1, APCS, KLK3, ARCN1, TRIM23, AREG, ARNTL, ARSA, STS, ARSD, ARSE, ARSF, ART1, ART3, ASL, ASNA1, ATR, AXL, BACH1, BARD1, BCHE, OPN1SW, BCR, BGLAP, BHMT, BLK, BNIP3, BNIP3L, BRCA2, BTG1, BTK, CAMK4, CANX, CBFB, CBL, CBLB, CCNF, CCT6A, CDK11B, CDK3, CDK6, CDK8, CGA, CHRM1, CHRM3, CHUK, TBCB, CLK1, CLK3, TPP1, CLN5, CCR5, COL3A1, COPA, CREB1, ATF2, CSNK1G2, CSNK1G3, CTH, CTSK, CTSV, CTSZ, CYLD, DAD1, DCX, DDB2, DDIT3, DMBT1, DYNC1H1, DYNC1I1, DYNC1I2, DPAGT1, DSP, E4F1, PHC1, PHC2, EEF1A2, EEF1B2, EGR2, EIF1AX, EIF2S3, ELK1, EPHA5, EPHB2, EPHB3, EYA4, ERCC3, ERG, EVPL, EXT1, EXT2, EXTL1, EXTL3, EYA1, EYA2, EYA3, EZH1, F7, F10, FANCF, FAP, FAU, EFEMP1, FKBP3, FKBP5, FRK, FSHB, FUT6, FUT8, FYB, GAD1, GAK, B4GALNT1, GALNT1, GATA6, BLOC1S1, OPN1MW, GFER, GGCX, B4GALT1, GLB1, GMDS, GOLGB1, GRK6, GRIA1, GUCY2C, GUCY2F, GUCY2D, HARS, HCK, HDGF, HEXB, HLCS, HMBS, HNRNPC, PRMT2, HSF4, HSPA9, IAPP, IGFALS, IGFBP2, IGFBP6, IL12RB2, INSRR, ITGAV, KCNE1, KCNH2, LIPE, LMAN1, SMAD9, MAN2B1, DNAJB9, MDH2, MGAT2, MGAT3, ATXN3, RPL10A, CNOT4, NRTN, NUP88, NUP98, OAS2, OXTR, P4HA1, PAH, PAM, PAPPA, PCBP2, PCK1, PCNA, PCSK5, CDK17, PDK4, PEX12, CFP, PFDN1, PFDN2, CDK14, PGGT1B, PGM3, PHEX, PHF2, PHKA1, PHKA2, PHKB, PHKG1, PIGC, PIK3C3, PPIB, PPID, PPM1A, PPM1B, PPP2CB, PPP4C, PPP3R1, PPP6C, PRKCI, PRKCQ, PRKCSH, PRKX, PROC, PSKH1, PTPN4, PTPN7, PTPN13, PTPRD, PTPRE, PTPRH, PTPRM, PTPRN, PTPRN2, PTPRS, RAB1A, RAB3B, RAB6A, RAB27A, RABGGTA, RABGGTB, RAD21, RAD52, RAG2, RANBP2, RANGAP1, RBBP6, OPN1LW, RGR, RNF6, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL36AL, RPL37, RPL37A, RPL39, RPL36A, RPN2, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, SALL1, SATB1, SBF1, SDF2, TRAPPC2, SEL1L, SETMAR, SFPQ, SFTPB, SFTPD, SGK1, SHMT2, SIAH1, ST6GAL1, ST8SIA1, SLC34A1, SLC25A1, SOX11, SP100, UAP1, SPRR1B, SPRR2A, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3, SRMS, SRP14, SRP19, SRP68, SRPK2, SSR1, STAT4, CDKL5, SULT1A3, SUV39H1, TAF5, TAF10, TARS, TBCA, TBCD, TBCE, TBL1X, TRAPPC10, TOP1, TOP2A, TOP2B, NR2C2, CCT3, TSHB, TTC3, TTF1, TUBA4A, TUBA3C, TUFM, TYRO3, UBA7, UBE2D2, UBE2E2, UBE2H, UBE2V2, UCP1, KDM6A, UTY, VBP1, VRK1, WEE1, WHSC1, XPC, XRCC4, TRIM25, ZBTB17, PRDM2, RNF103, TUBA1A, SCG2, BRPF1, RAB7A, EPM2A, TUSC3, NUP214, SLC25A16, AAAS, HMGA2, GAN, CLPP, USP11, USP9X, KDM5C, SMC1A, UBL4A, USP9Y, HIST1H4I, BAP1, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, DYRK2, CUL4A, CUL2, TPST2, TPST1, FKBP6, PPM1D, HAT1, COPS3, CBX4, CDC14A, DENR, STK16, SLC25A12, RUVBL1, USO1, CDK13, DDX3Y, DYNLL1, GALNT4, B4GALT4, B4GALT3, B3GALT2, TNK1, CTSF, RNGTT, RIOK3, DYRK4, TRIM24, CDKL1, DPM2, PROZ, EIF2S2, HERC2, HIST1H3F, P4HA2, USP13, KALRN, CDKL2, RNF8, BAZ1B, UBA3, RPL14, EIF1AY, USP2, USP8, ATP6V0D1, SMC3, ATG12, DYRK1B, CTDP1, AURKB, STK17B, STK17A, COPB2, COPS2, GTF3C4, B4GALT6, B4GALT5, RPL23, UBE4A, COG1, ARHGEF6, PICK1, PIGL, GAL3ST1, EEF1E1, GOSR1, RAB3D, SEC22B, GTPBP1, GOSR2, CLOCK, CDC42BPB, RNF7, AATK, SNCAIP, NUP155, TTLL4, NUP93, UBE3C, SETD1A, MAML1, TATDN2, TOMM20, SPOCK2, CUL7, DNAJC6, SETDB1, KLHL21, SUPT7L, RNF10, USP3, NR1H4, PDCD6IP, GNE, PIGK, SH2D3C, SH2D3A, UBA2, SAE1, COL4A3BP, SGK2, PREB, PDIA6, ABI2, CHST4, SLC25A13, SLC25A15, TRIM13, ZMPSTE24, CWC27, SPEG, TRAIP, BCKDK, MARCH6, TMEM5, B3GNT3, TRIM22, SPON1, UBAC1, SEC24B, RBM14, PPIE, PPIH, COG5, TRIM38, UBE2E3, SLC25A17, SEC23A, CARM1, PRDX4, SLC35A1, SLC34A2, CCT7, CCT4, CCT2, ERN2, ERLIN1, RBCK1, STAMBP, TRIM16, EXOC5, YKT6, FARS2, DCTN6, FUT9, RRH, USP39, YME1L1, STAG2, NUP50, SEC24A, USP20, BRD8, AFG3L2, KDELR1, SEC61B, PDIA5, OS9, TMED2, CKAP4, COPS6, KDELR3, PIM2, WWP1, WWP2, WDR5, ADAMTS13, ADAMTS5, NUPL2, PTPN21, ATE1, PRDM7, PRDM5, CIT, PTPRT, KAT7, FICD, ERLIN2, ADAMTS7, RPL35, SEC63 |
2059 | GO:0051716 | 0.00 | 1.24 | 546.11 | 607 | 1720 | cellular response to stimulus | A2M, ABAT, ABCA4, ACPP, ACTB, ACTG1, ADORA3, ADRA1B, JAG1, APLNR, AGXT, ALK, ALOX15B, ANXA6, BIRC5, APLP2, KLK3, TRIM23, AREG, ARF1, ARL4D, ARF5, ARF6, ARHGAP6, ARHGDIB, ARL1, ARL2, ARR3, ATOH1, AVP, ADGRB1, ADGRB2, OPN1SW, BCR, BICD1, BLK, DST, BSG, BTK, BUB1B, C3, CAPN5, DAGLA, CACNA1A, CACNB3, CACNB4, CALCR, CASQ1, CBLB, CCK, KRIT1, CCND3, CD3D, CD3E, CD3G, CD4, CD5, CD7, CD8A, CD8B, TNFSF8, CD37, CD38, CD53, CD59, CD72, CD79B, ADGRE5, CD151, CDA, CDC20, CDC25C, CDH3, CDH6, CDH17, CDK4, CENPA, CENPE, CENPF, CGA, CHN1, CHN2, CHRM1, CHRM3, CHRNB2, CHRNB4, CLCN6, CLPS, LTB4R, CNR1, CNR2, COL4A3, COL15A1, CORT, CLDN3, CR2, CREBL2, CRYBA1, CSNK1G2, CSNK1G3, CSNK2A1, CSPG4, CTF1, CTNND2, CYBB, DGKA, DGKB, DGKQ, DBH, DCC, DCX, DFNA5, DHCR24, DIAPH2, DMBT1, DNM1, DOK1, DRD3, RCAN1, DTNA, E2F2, GPR183, S1PR1, S1PR3, EFNA1, EFNA3, EFNA4, EFNB1, EIF2B1, EMP2, EPHA1, EPHA7, EPHA8, EPHB2, EPHB3, EPS8, EPS15, ERG, EVC, EXT1, EXT2, F2R, F2RL2, F10, FBLN1, EFEMP1, FCER2, FCGRT, GPC4, FGG, FGR, FLT3LG, FPR1, FPR3, FRK, CENPI, GAST, FYB, FZD2, GABRA4, GABRA6, GABRE, GABRG1, GABRR1, GABRR2, GALR1, OPN1MW, GDI1, GDI2, GFRA1, GFRA2, B4GALT1, GHRH, GMDS, GNA15, GNAL, GNAQ, GNAT2, GNAZ, GNGT2, GNRH2, GPR1, GPR3, GPR4, UTS2R, GPR15, GPR19, LPAR4, GPR26, FFAR1, GRK6, GRB7, GRIA1, GRIA4, GRID1, GRID2, GRN, GRIK3, ARHGAP35, GRM8, GRPR, GTF2I, GUCY2C, HIP1, HIVEP2, HOXD3, HRC, HRH2, HTR2C, IAPP, ICAM2, ICAM3, SP110, IGFALS, IGFBP3, IGFBP6, IHH, IMPA1, INHA, INPP1, INPP4A, INSL3, INSL4, ITGAD, ITGAM, ITGAV, ITGAX, ITGB4, CD82, KCNN4, KIF5A, KISS1, KLRB1, KLRC2, KLRC3, KLRD1, KLC1, KRT19, LAMA5, LIMK1, LLGL2, LRPAP1, BCAM, TACSTD2, EPCAM, MAL, CD46, MGAT3, PPP1R12A, PPP1R12B, SEPT2, NRTN, NTF3, NTF4, NTSR1, OMP, OR1D2, OR1F1, OR2C1, OR3A2, P2RX1, P2RX3, PDC, PDE4C, PDE6H, PDE7A, PDE8A, PDGFRL, ENPP2, PDYN, PFKFB1, CDK14, PGAM2, PIGR, PIK3C2B, PI4KA, PLN, PPP1R1A, PPP1R2, PPP2R1B, PPP3R1, PRKCSH, RELN, PYY, TAS2R38, PTGER1, PTHLH, PTH2R, PTPN13, PTPRD, PTPRJ, PTPRM, PTPRR, RAB1A, RAB3B, RAB4A, RAB5A, RAB5B, RAB6A, RAB27A, RAB27B, RABIF, RAB5C, RAC3, RANBP1, RAP1GDS1, RAP2B, RBP1, RBP2, OPN1LW, PRPH2, DPF2, RFNG, RGR, RGS2, RGS10, RGS12, RGS13, RGS16, RLN1, RPS27, RREB1, CLIP1, RSU1, S100A1, S100A4, S100A6, S100A11, S100A13, SALL1, TSPAN31, SCTR, SDC2, SDC4, SEC14L1, SELE, SELP, SEMA3F, SFRP5, SH3BGR, SH3BGRL, SH3BP2, SHB, SIAH1, STIL, SIX3, SLC20A1, SOX2, SOX10, SPINK1, SPN, SPOCK1, SRMS, SRPK2, TROVE2, STRN, STYX, TACR3, CNTN2, TBL1X, DYNLT1, TSPAN7, TNFAIP6, TRHR, TRIP6, TRPC3, TSG101, TSHB, TTK, TUFT1, TULP3, TYRO3, TYROBP, UPK1B, UCN, SCGB1A1, KDM6A, VDAC2, VIM, VIP, VIPR1, VIPR2, LAT2, CORO2A, YWHAZ, ZIC1, ZIC2, ZNF217, ZP2, SEMA3B, STAM, ANP32A, RND2, MADCAM1, CLTCL1, FZD6, FZD9, HIST1H3A, HIST1H3E, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, OR1A1, OR1D5, OR1E1, OR1E2, OR1G1, OR3A3, SPARCL1, BCAR3, SORBS2, CNTNAP1, IKBKAP, CAMK1, OR6A2, RFXANK, UNC5C, SSNA1, DCHS1, PTCH2, NUMB, PDE5A, DYNLL1, S1PR4, TNK1, CTNNAL1, HRK, TNFSF10, TNFSF9, ADAM15, RAB11A, RGS11, DLK1, PEX11A, INPP4B, CFLAR, WISP3, WISP1, HCAR3, EIF2B2, AP1M1, WASF1, BAIAP3, AP3D1, HIST1H3F, TRPA1, CDKL2, RHBDL1, TAAR5, DOK2, ANGPTL1, DIRAS3, UNC119, USP8, DGKI, RASSF9, ZW10, REPS2, CRLF1, GPR50, DHRS3, STK17B, STK17A, CYTH3, BCL7B, TAAR2, GPR55, S1PR2, TRIP10, RAB9A, SLC9A3R1, NRXN3, NRXN2, GRAP2, ARHGAP29, THEMIS2, RAB3D, GTPBP1, GABBR2, CDC42BPB, AKAP12, RAB36, RIN1, AATK, GNA14, CLCA2, RALGPS1, ZNF516, SDC3, TTI1, RIMS2, SEMA3E, GPRASP1, IFT140, ARHGAP32, RAPGEF5, SNX17, CKAP5, MAML1, SPOCK2, KIAA0141, ELMO1, GAB2, FARP2, TRIL, RHOBTB1, P2RY14, ARHGAP25, ABI1, ZBTB33, SH2B3, FRAT1, TOM1L1, RANBP9, ABCC9, PDCD7, GPC6, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN2, TSPAN1, ARPC2, SGK2, ARL4C, ARL4A, ARFRP1, G3BP1, ABI2, ATP6AP2, FARP1, WASF2, SORBS3, TNK2, RNF41, RCAN2, STAM2, AKAP8, SIGMAR1, APC2, TNIP1, TRDN, ABCA7, CACNG2, SEMA3A, CDC42EP2, CAP1, SEMA6C, SEMA6B, SEMA4F, SEMA4D, SEMA4B, PRDX4, ARPC1A, OLFM4, ARFGEF2, ARFGEF1, SIVA1, CDC42EP3, HEXIM1, STAMBP, IVNS1ABP, TRIM16, PDPN, RASL10A, KHDRBS1, EBP, RRH, CNPY3, NRG3, GRAP, CHL1, TRAF3IP2, AHCYL1, OR5I1, PDE10A, USP20, CD300C, PROKR1, GPR83, MALT1, BRD8, YWHAQ, RAB32, KIF2C, IFT27, PIM2, UPK1A, OGFR, WWP1, RAPGEF4, ESM1, ADAMTS13, CIT, BTN3A1, PTPRT, RCAN3, CD160, ZWINT, IL1RAPL1, RABL2B, RABL2A, NUDT4, RASSF8 |
2060 | GO:0045184 | 0.00 | 1.24 | 271.65 | 306 | 743 | establishment of protein localization | ABCA1, ACVR2B, ADAR, ADCY5, ADRA2A, ANGPT1, ANXA1, ANXA5, APOA1, ARCN1, ARL4D, ARF5, ARL2, ARNTL, RERE, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, AZGP1, BARD1, BBS4, BCL3, BNIP3L, BRCA2, BTF3, TSPO, VPS51, CACNA1A, CALCR, CANX, CBLB, CD3G, CD36, SCARB2, CD63, CDKN1A, CDKN2A, CENPF, CHRM3, AP1S1, AP2S1, CLU, CLTA, CNR1, COL1A1, COPA, CRP, CSE1L, CYLD, DMBT1, DNM2, DRD3, EFNA5, EGR2, EIF5A, CTTN, EPHA5, EPS15, FBLN1, FYB, GDI2, GFER, GHSR, GJA5, GLE1, GLP1R, GNAQ, GNAS, HIST1H1B, HMGCR, FOXA2, HSPA8, HSPA9, IFIT1, IFNA2, RBPJ, IL1RN, ITPR1, ITPR2, JUN, KCNC2, KCNJ11, KCNS3, KPNA2, KPNA3, KPNA4, KPNA5, TNPO1, LAMP2, LLGL2, LTBP2, TONSL, SLC11A2, NUP88, NUP98, OGG1, OR1D2, PRDX1, PAM, PARK2, CHMP1A, PCSK5, PDE3B, PDE4C, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX14, PIK3C3, PPM1B, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PSEN1, PTPN1, PTPRN, PTPRN2, RAB1A, RAB3B, RAB4A, RAB5A, RAB5B, RAB6A, RAB27A, RAB27B, RABIF, RAB5C, RAF1, RAN, RANBP2, RANGAP1, RAP2A, REST, RFX3, RPGR, RTN2, RYR2, S100A12, S100A13, CX3CL1, SEL1L, SFRP5, SIX3, SLC2A1, SLC11A1, SLC15A1, SLC15A2, SLC16A1, SNAP25, SP100, SREBF1, STAT3, STXBP1, STXBP2, STXBP3, STYX, ABCC8, SYT5, CNTN2, HNF1A, DYNLT1, TNFAIP3, HSP90B1, TRAF2, USH2A, VIP, WHSC1, ZP2, SCG2, RAB7A, NUP214, STAM, CUBN, AAAS, AKAP1, CLTCL1, FZD7, DYRK2, ITGA8, AP3B1, RGS20, USO1, CADPS, SSNA1, AKR1C3, VAMP8, STX16, STX11, STX10, BECN1, LIN7A, AP1S2, AP1M1, HERC2, AP3D1, SELENBP1, SYT7, UNC119, ATP6V0D1, SEC22C, RABEP1, AP4M1, ARHGEF2, RASSF9, ZW10, COPB2, TRIP11, HMGN3, SNAP29, RAB33A, RAB9A, ZFYVE9, COG1, CRIPT, EIF2AK3, PICK1, ATG5, LITAF, GOSR1, BAG4, RAB3D, APBA3, ATP6V1G1, SEC22B, VPS26A, GOSR2, CLOCK, AKAP12, RAB36, ABCG1, NUP155, IPO13, NUP93, TRAM2, RIMS2, IFT140, ACAP1, ZFYVE16, SNX17, IST1, TOMM20, KEAP1, SNAP91, NR1H4, DOPEY2, HDAC6, PDCD6IP, PDCD6, TOM1L1, TOM1, AP1M2, KIF20A, PREB, CALCRL, STAM2, RAMP2, APC2, KATNB1, IKZF1, SEC24B, TACC3, COG5, SEC23B, SEC23A, CREB3, APPBP2, ATG7, ARFGEF2, ARFGEF1, TXNIP, EXOC5, YKT6, TNFSF13B, CCT6B, GIPC1, TRAF3IP2, NUP50, AHCYL1, CPLX1, RUVBL2, AFG3L2, KDELR1, AP3M2, TOMM34, OS9, RAB32, KDELR2, KDELR3, IFT27, RAB35, WWP2, RAPGEF4, NUPL2, BTN3A1, CDC37, AP4S1 |
2061 | GO:1902589 | 0.00 | 1.24 | 376.85 | 422 | 1023 | single-organism organelle organization | ABL1, ABL2, ACTG1, ACTN1, ADD1, ADRA2A, ADRB2, AKT2, ANG, ANXA1, ANXA5, BIRC5, APOA1, ARF6, ARHGAP6, ARHGDIB, ARL2, BAD, BAX, BBS1, BBS2, BBS4, BCL2, BCL2A1, BCL2L1, BCR, BICD1, BID, BMP4, BNIP3, BNIP3L, BST2, BUB1B, TSPO, CAMK2A, CAPG, CAPN6, CAPZA1, CAPZB, CASQ1, CASQ2, CAV2, CAV3, CCNF, CCNG1, CCNG2, CD28, CDK11B, CDC25A, CDC25C, CDC27, CDC42, CDK3, CDKN2A, CENPA, CENPE, CENPF, CETN1, CFL2, CHD3, CHD4, CLCN3, CNN1, CNN2, CNN3, CNP, COX8A, CSF1R, CSNK2A1, CSNK2A2, CTGF, CTNNA1, CTSK, CTSV, CXADR, CYLD, DAPK3, GADD45A, DIAPH1, DIAPH2, DNAH5, DYNC1H1, DPYSL3, DRD3, DUSP1, E2F4, E4F1, S1PR1, LPAR1, EDN3, EFNA5, EIF2S1, EML1, EMP2, CTTN, EPB41, EPB41L2, STOM, EPHA1, EPHA5, EPS8, F2RL1, FANCC, PTK2B, FANCF, FCGR3B, FGD1, FGF7, FGFR3, SLC37A4, GABRA5, GAPDH, BLOC1S1, GHSR, SFN, GRB2, CXCL1, HSD17B10, HARS, HCK, HCLS1, HGF, HIF1A, ONECUT1, HRG, HSPA4, HSP90AA1, ICAM1, IGF1, IGF1R, IGF2, IL1A, ILK, INS, INPPL1, INSRR, ITGB1, KCNK3, KIT, KLC1, KIF25, KRAS, KRT15, KRT19, LAMA5, ABLIM1, LIMK1, LLGL2, LRMP, TACSTD2, SMAD3, MAP6, MDH1, MYO1B, PPP1R12A, NUBP1, SEPT2, NTF3, NTHL1, NTRK3, NUMA1, NUP88, OPA1, P2RX5, PAM, PARK2, PAWR, PCM1, CHMP1A, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX14, PFN1, PFN2, SERPINB10, PIK3C3, PPP3R1, PRKCE, PRKCZ, PTEN, PTGER4, PTK2, PTPN1, PEX19, PEX5, RAB13, RAC1, RAC2, RAC3, RALA, RAN, RAP2A, RB1, RDX, RFX3, RGS2, RPGR, RPL24, RPS3, CLIP1, S100A9, S100A10, CCL21, CCL24, SDC4, SDCBP, SFRP4, SGK1, SHC1, STIL, SLC1A3, SLC9A1, SLC16A1, SLCO1A2, SLC22A3, SNAP25, FSCN1, SNRPD1, SNRPF, SON, SPAG1, SPAG4, SPAST, SRF, STAT2, STAT3, STXBP1, SUPV3L1, SYP, SYT1, SYT4, TAC1, TACC1, CNTN2, TAZ, TBCD, TBCE, DYNLT3, DYNLT1, TMF1, TMOD1, TNNT2, NR2C2, HSP90B1, TSC1, TSG101, TTK, TUBG1, TUFM, U2AF1, CLRN1, UVRAG, VIL1, CORO2A, WEE1, WNT11, YWHAZ, ZIC2, ZBTB17, ZNF189, ZNF207, ALMS1, FZD5, RAB7A, ARHGEF5, NUP214, CSRP3, CHAF1B, CLTCL1, USP9X, DYSF, PICALM, UXT, EEA1, SORBS2, GAS7, CDC14A, DENR, CDK13, SSNA1, DYNLL1, VAMP8, STX16, STX11, STX10, BECN1, CDC23, RAB11A, CFLAR, CDC16, WASF1, SEMA5A, LATS1, ATP6V0D1, SEC22C, AIFM1, CCNB2, ATG12, CTDP1, ARHGEF2, PDLIM7, ITGB1BP1, S1PR2, TRIP10, SNAP29, TAOK2, SLIT2, SLC9A3R1, KIF3B, NRXN1, NRXN2, RECQL5, PEX16, CRIPT, PICK1, CHST3, ONECUT2, TBPL1, GOSR1, BAG4, BCAR1, CDC42BPB, MAD2L1BP, CEP135, NUP93, KIAA0391, CROCC, SEMA3E, IFT140, SLK, KIAA0101, ATG13, DLGAP5, CKAP5, PHYHIP, IST1, TOMM20, CUL7, ARHGEF11, ARHGEF17, ELMO1, C2CD5, KIAA0753, FARP2, CEP350, KLHL21, FGFBP1, ABI1, PDCD6IP, BCL2L11, TOM1L1, RANBP9, COL4A3BP, ARPC5, ARPC4, ARPC3, ARPC1B, ARPC2, KIF20A, AKAP9, ABI2, WASF2, SORBS3, SPRY1, ABCC4, AKAP8, APC2, KATNB1, TRDN, CORO2B, ANAPC10, RAPGEF3, CDC42EP2, ACAA2, VAV3, BAIAP2, MAD2L2, TACC3, CAP1, SSSCA1, ARPC1A, ARFGEF1, SIVA1, TACC2, SORBS1, ERN2, CDC42EP3, GAS2L1, YKT6, DCTN6, AVIL, STAG2, ARPP19, VAMP5, SEPT9, JTB, TXNL4A, AFG3L2, YWHAQ, IMMT, KIF2C, IFT27, PAPD7, UBE2C, STMN2, TPPP, HSF2BP, CIT, KIF3A, ZWINT, CAPN10, KPTN, CDC37, CORO1A, WDHD1, ADAMTS7, CHEK2, FZD10 |
2062 | GO:0030154 | 0.03 | 1.23 | 126.23 | 143 | 372 | cell differentiation | AAMP, ADRB2, APAF1, BIRC2, BCL3, BLK, BNIP3, BRDT, CAT, CD3D, CD3E, CD4, CD8A, CD28, TNFSF8, CDK9, CDX1, CDX4, CENPF, TBCB, COL15A1, CR2, ATF2, CSRP2, CYLC1, CYLC2, CYP24A1, DAZ1, DDX5, DHX9, DHCR7, DTYMK, GPR183, TYMP, EDA, ELAVL3, ELK1, EMP2, ERF, ETV3, ETV6, EXT2, FCER1G, FGR, FLOT2, FLT1, FRK, NR5A1, GAS1, GJB5, GPLD1, HIST1H1T, HSD17B10, HCK, HIP1, HLF, HMGCR, NR4A1, HMX2, HNRNPC, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGF2, IL10, ITGAM, SMAD6, MAL, ALDH6A1, ODF1, PURA, RAG2, RFNG, RGS2, RPL22, RPS3A, RPS11, SATB1, SFRP5, SRSF4, SHB, SIM2, SLC2A4, SOX12, SPIB, SPN, SRD5A1, SRMS, SRPK2, SRY, STAT6, SUV39H1, ADAM17, TNNI3, TNP2, TOP2A, TPD52, TSPY1, UCP1, VCAM1, YY1, ZIC1, ZIC2, ZNF3, KCNAB1, SLC7A5, FKBP6, RGS20, TNK1, DLK1, PEX11A, SAP30, AP1M1, INA, KRT75, DYRK1B, DDX21, BCL7B, GTF3C5, HAND1, SOX13, ZNF516, SPOCK2, SPATA2, ZBTB24, NR1I3, NR1D2, HDAC6, SH2B3, ARL4A, TNK2, APC2, CITED2, GPNMB, VAMP5, CPLX2, ARID5A, MALT1, EDAR, RAB32, GLMN |
2063 | GO:0044238 | 0.00 | 1.22 | 418.99 | 460 | 1312 | primary metabolic process | ABCA3, ABCA4, ACAA1, ACADM, ACADS, ACADSB, ACAT2, ACLY, ACP1, ACTB, ACY1, ADAM10, ADD1, ADH5, AGA, AGXT, ALAS1, ALAS2, ALB, ABCD1, ALDH1A1, ALDH1A3, ALDH9A1, ALDH3A2, ALOX15B, AMHR2, AMT, KLK3, TRIM23, ARG1, ARG2, ARSA, STS, ARSD, ARSE, ARSF, ASL, ASNA1, ASS1, AUH, AXL, BCAT1, BCHE, BCKDHA, OPN1SW, BCR, BGLAP, BLK, BNIP3, BNIP3L, C1QA, C1QB, C1QC, C1S, CAPN5, DAGLA, CAPN1, CAPN6, CASP4, CASP5, CASP6, CBR1, CCBL1, CCNF, CDK3, CDK6, CDO1, CFTR, CHAT, AKR1C4, CHKB, CHRM1, CHRM3, TBCB, CKM, CLCA1, TPP1, CLPS, CCR5, COL3A1, COL11A1, CPA1, CPD, CPT1B, CPT2, CR2, CRAT, CSNK1G2, CSNK1G3, CTRB1, CTSD, CTSE, CTSK, CTSV, CYP2A6, CYP2A13, CYP2F1, CYP3A4, CYP8B1, CYP11B1, CYP24A1, CYP51A1, DBI, DBT, DCX, DECR1, DMBT1, SARDH, DPP4, DPP6, DSP, ECH1, PHC1, PHC2, EEF1B2, EIF1AX, EIF2S3, EPHB2, EPHB3, EVPL, EXTL3, F7, F10, FAAH, FABP2, FABP6, FABP7, ACSL4, FAP, FCN2, FDFT1, FDPS, FDXR, FKBP3, FKBP5, FYB, GAD1, GAD2, GAK, GATM, BLOC1S1, OPN1MW, GFER, GGCX, GGT7, GLDC, GLUD1, GLUL, GP9, GRK6, GPT, GSTZ1, GZMH, HAL, CFHR1, HLCS, HMBS, HMGCL, HMGCS1, HMGCS2, HNMT, HP, HPGD, HSD11B1, HSPA9, IAPP, IGFALS, IGFBP2, IGFBP6, IL1RAP, IL1RN, IL12RB2, IDO1, INPP4A, INSRR, IVD, KCNH2, KLK1, KRT1, LCAT, LIPC, LIPE, FADS3, LTA4H, DNAJB9, MEP1A, MEP1B, NRTN, OAT, OLR1, OTC, OXCT1, OXTR, P4HA1, PAFAH1B2, PAFAH1B3, PAFAH2, PAH, PAPPA, PCSK5, CDK17, PCYT1A, PEPD, PEX7, PEX12, PEX13, PFDN2, CDK14, PGC, PGGT1B, PHEX, PIGC, PIK3C2B, PIK3C3, PI4KA, PIP4K2A, PPIB, PPM1B, PPP2CB, PRCP, PREP, PRKX, PROC, PSKH1, PSPH, PTGS1, PTPN4, PTPN7, PTPN13, PTPRD, PTPRE, PTPRH, PTPRM, PTPRN, PTPRN2, PTPRS, ABCD3, PYCR1, ALDH18A1, QDPR, RAB3B, RAB6A, RAB27A, RABGGTA, RABGGTB, RANGAP1, RBP1, RBP2, OPN1LW, RGR, RNPEP, RPE65, RPL36AL, ACSM3, SBF1, SFTPB, SHMT2, SIAH1, SLC1A3, SLC6A6, SLC7A4, SLC10A1, SLC10A2, SLC12A1, SLC16A1, SLC34A1, SLCO1A2, SMS, SPRR1B, SPRR2A, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3, SRD5A1, SRMS, SRP14, SRP19, SRP68, SSR1, ST14, CDKL5, SUOX, TAT, TBCA, TBCD, TBCE, TMPRSS2, TPSAB1, TSHB, TST, TTC3, TUBA4A, TUBA3C, TUFM, TYR, TYRO3, TYRP1, UBE2E2, UBE2H, KDM6A, UTY, VBP1, TRPV1, VRK1, WEE1, RNF103, TUBA1A, SCG2, CUBN, SLC25A16, GAN, SLC7A5, CLPP, USP11, UBL4A, ACOX2, ACOX3, BAP1, PIP5K1B, BBOX1, SOAT2, TPST2, TPST1, PPM1D, DGKZ, DDO, AGPS, CDC14A, DENR, HSD17B6, ALDH4A1, DGAT1, TNK1, CTSF, ADAM19, ADAM15, RIOK3, DYRK4, PEX11A, CDKL1, INPP4B, GGH, ALDH1A2, PROZ, EIF2S2, P4HA2, KALRN, CDKL2, CH25H, RHBDL1, EIF1AY, USP8, ATP6V0D1, ATG12, PCSK7, DHRS3, NUMBL, STK17B, STK17A, UBE4A, ZFYVE9, TMPRSS11D, FADS2, ARHGEF6, PIGL, ADAMTS4, ADAMTS3, ADAMTS2, ADAMTS1, RAB3D, CDC42BPB, PREPL, PRDX6, RNF7, KLK4, AATK, SNCAIP, CLCA2, TTLL4, UBE3C, ADAMTSL2, SNX17, PTDSS1, TOMM20, SCRN1, SPOCK2, CUL7, DNAJC6, FIG4, KLHL21, JOSD1, HS3ST4, PDCD6IP, PIGK, SH2D3C, SH2D3A, UBA2, SAE1, DPP3, COL4A3BP, SGK2, PDIA6, ABI2, AASS, SLC25A15, DHRS9, DHRS2, GLYAT, ZMPSTE24, SPEG, TRAIP, BCKDK, MARCH6, CEPT1, UBAC1, CDIPT, ACAA2, ECI2, UBE2E3, SLC25A17, PRDX4, SLC34A2, SLCO1B1, STAMBP, PDPN, EXOC5, EBP, RRH, CORIN, YME1L1, CAPN9, FAXDC2, ALDH1L1, ADAM28, USP20, DHRS4, AFG3L2, PRSS21, SEC61B, PDIA5, SERINC3, ACOT2, CKAP4, SLC27A5, SLC27A4, SLC27A2, KLK11, KDELR3, PTPN21, ATE1, HIBADH, CIT, PTPRT, CAPN11, CAPN10, FICD, C14orf1, SEC63 |
2064 | GO:0090304 | 0.00 | 1.20 | 812.77 | 883 | 2216 | nucleic acid metabolic process | AARS, ABCA2, ACTN1, ACVR1, ACVR2A, ACVR2B, ADAR, ADARB1, ADRB2, AEBP1, JAG1, AGTR2, NR0B1, AKT2, ALK, ALX3, ANG, BIRC2, XIAP, BIRC5, APP, PHOX2A, ARNT, ARNTL, ASCL1, ASCL2, ATF4, RERE, ATOH1, AZGP1, CCND1, BCL3, BCL7A, BICD1, PRDM1, BMI1, BMP1, BMP3, BMP8B, BMPR1A, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTG1, BTK, BYSL, CAMK4, CAMK2A, CAT, RUNX2, RUNX1T1, CBFB, CBL, CCNB1, CCNC, CCNT1, CCNT2, CD3D, CD80, CD86, TNFSF8, CD36, CD38, CD81, CDK11B, CDH1, CDK8, CDX1, CDX2, CDX4, CEBPE, CENPB, CGA, CHD1, CHD2, CHD3, CHD4, CHUK, CLU, CLK1, CLK3, CLNS1A, COL1A1, COX4I1, COX5B, COX6A1, COX6B1, COX7C, COX8A, CREB1, ATF2, CREBL2, CRX, CRY1, CRY2, CRYM, CSNK2A1, CSNK2A2, CSTF3, CTH, CTNND2, CYLD, DAB2, DGKQ, DAPK3, DCN, DDIT3, DDX5, DDX6, DHX9, DDX10, DHFR, DLX5, DLX6, DNM2, DRD3, ARID3A, RCAN1, TSC22D3, DYRK1A, E2F2, E2F4, E2F6, EBF1, ECM1, EDA, S1PR1, EFNA1, EGR2, EGR3, EGR4, EIF4A1, EIF4E, EIF4G1, ELAVL2, ELK1, EMX1, EMX2, EN1, EPHA5, EPRS, ERBB2, ERF, ERG, ERN1, ESR1, ESRRG, ETF1, ETS1, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EZH1, F2R, F2RL1, FAU, FBN1, EFEMP1, FGF4, FGF7, FGFR3, FLI1, AFF2, FRK, FSHB, NR5A2, NR5A1, FZD2, GABPA, GALR1, GAS6, GATA4, GATA6, GCG, KAT2A, NR6A1, GDF9, GFI1, GPC3, GLS, SFN, GPS2, GPX2, ARHGAP35, GRSF1, GSC2, GTF2F1, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, H2AFZ, HSD17B10, HARS, HBE1, HCK, HCLS1, HDGF, HEXB, NRG1, HHEX, HIC1, HIF1A, HIP1, HIVEP2, ZBTB48, HLF, HLX, NR4A1, HMX1, HMX2, FOXA2, HNF4G, ONECUT1, HNRNPD, HOXC10, HOXC11, HOXD3, HOXD8, HOXD9, HOXD10, HOXD11, HOXD12, PRMT2, HES1, HSF4, HSPA8, ICAM1, IFI16, SP110, IFNA2, IGBP1, IGF2, IHH, IL1A, IL1B, IL17A, ILF3, ILK, ING2, INSIG1, EIF3E, IRAK1, IRAK2, IRF1, IRF2, IRF5, ISL1, ITGA3, JARID2, JUND, KIT, KRAS, AFF3, ABLIM1, LMO1, LTF, LUM, EPCAM, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MEOX2, CIITA, AFF1, FOXO4, CITED1, PPP1R12A, DRG1, RPL10A, CNOT2, CNOT4, NRL, YBX1, NTF3, NTRK1, NTRK3, NUP88, OAS2, OAS3, SIX6, OTX1, OTX2, OVOL1, P2RY1, PA2G4, PCSK6, PRDX1, SERPINE1, PAM, PARK2, PAWR, PAX3, PAX4, PAX9, PBX1, PCBP2, PCK1, CHMP1A, PDE8A, ENPP2, ENPP3, PER1, PEX14, PF4, PFDN1, ATP8B1, PFN1, PGR, PHF2, PIM1, PRRX1, PPID, PPM1A, PPP1R8, PPP2R2A, PPP3R1, PRKAA1, PRKAG1, PRKAR1A, PRKCI, PRKD1, PRKCZ, EIF2AK2, RELN, PSEN1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PTAFR, PTEN, PTGIS, PTHLH, PTMA, RAF1, RANBP2, RARA, RARB, RB1, RBL1, RBL2, RBM4, RBMS2, RELB, DPF2, REST, RFX1, RFX2, RFX3, RFXAP, RGS12, RHEB, RNASE1, RNASE2, RNASE6, RNF6, ABCE1, RP9, RPL3, RPL3L, RPL4, RPL5, RPL7, RPL10, RPL11, RPL13, RPL22, RPL24, RPL27, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3A, RPS4X, RPS4Y1, RPS6, RPS6KA1, RPS11, RPS19, RPS20, RPS23, RPS25, RPS27, RPS28, RPS29, RREB1, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A12, SALL1, SATB1, XCL1, TRAPPC2, SFRP4, SFRP5, SRSF1, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SFSWAP, SGK1, SIM2, SIX1, SIX3, SLC9A1, SLC11A1, SMARCA2, SMARCA4, SMARCC2, SMARCD1, SMARCD3, SMARCE1, SNAI1, SNAPC1, SNAPC2, SNAPC3, SNCA, SNRNP70, SNRPA1, SNRPC, SNRPD1, SNRPD2, SNRPE, SNRPF, SNRPN, SOD2, SON, SOX1, SOX2, SOX3, SOX9, SOX10, SOX11, SOX12, SP1, SP4, SPIB, SREBF1, SRF, SRPK2, SRY, TRIM21, TROVE2, STAT1, STAT2, STAT3, STAT4, STAT5B, SUPT4H1, SUV39H1, TAF2, TAF4B, TAF5, TAF6, TAF7, TAF10, TAF13, TAL1, TAL2, TARS, TBL1X, TBP, HNF1A, ZEB1, ZNF354A, NR2F1, NR2F2, KLF10, TMF1, TMPO, TNFAIP3, TNFRSF1A, TNNI2, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TSC1, TSC2, TSG101, TULP3, TNFRSF4, U2AF1, UBE2D2, UBE2L3, UBE3A, UBTF, UCP1, SCGB1A1, USP4, NR1H2, USF1, VAV1, WFS1, WNT1, WNT2, WNT11, YWHAZ, ZFP36, ZFP37, ZFPL1, ZIC1, ZIC2, ZNF3, ZNF711, ZNF7, ZNF8, CNBP, ZNF708, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZSCAN21, ZNF41, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF99, ZNF124, ZNF132, ZNF136, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF217, ZNF223, ZNF224, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, ZXDA, PRDM2, CSDE1, PAX8, FZD5, BRPF1, AIMP2, ARHGEF5, ZNF212, BRD3, NUP214, CSRP3, FOSL1, FGF23, AAAS, ANP32A, ZNF239, DPF1, NRIP1, USP9X, RBM10, KDM5C, USP9Y, PICALM, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, SOX14, UXT, ZNF282, CUL3, CUL2, FOXN1, KLF11, OGT, ITGA8, IKBKG, IKBKAP, HAT1, GAS7, CBX4, CAMK1, PIR, BLZF1, PRPF18, RRP1, KHSRP, STK16, RGS20, KLF7, CDK13, RFXANK, TP63, RNASET2, CHRD, DDX3Y, DYNLL1, SRSF9, TRADD, EDF1, URI1, EED, RNGTT, RIPK1, RIPK2, TRIM24, SAP30, HESX1, CFLAR, HDAC3, TSC22D1, KAT2B, PER3, TAX1BP1, BUD31, CPNE1, PHOX2B, HIST1H2AG, USP13, RPS6KA4, TNFSF18, TAF1C, TAF1B, TAF1A, UBA3, RPL14, USP2, PDLIM1, RQCD1, PRPF3, CBFA2T2, DYRK1B, CTDP1, COX7A2L, SCAF11, ARHGEF2, DDX21, SLC33A1, CCPG1, ITGB1BP1, ZNF235, TRIP11, HMGN3, GTF3C5, GTF3C4, GTF3C3, CNOT8, EFTUD2, RPL23, CER1, CIAO1, ZRANB2, SNRNP40, DDX23, HAND1, ZNF264, QKI, EIF2AK3, FHL5, ATG5, ONECUT2, LITAF, TBPL1, EEF1E1, ZNF254, GTPBP1, CLOCK, SOX13, RBM39, RNF14, ABCG1, NUP155, ZNF592, CTR9, ZNF516, VGLL4, NUP93, BZW1, KIAA0391, DHX34, ST18, ZNF646, SETD1A, HDAC4, ZFYVE16, BCLAF1, EIF4A3, MAML1, RNF40, KEAP1, TSC22D2, RB1CC1, ARHGEF11, ZEB2, ZBTB24, ZNF518A, SETDB1, DDX46, SMG7, SUPT7L, RNF10, ZBTB5, RBM8A, EXOG, NR1I3, NR1H4, NR1D2, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, PDCD7, PREB, ZNF263, G3BP1, SUGP2, ZNF256, SORBS3, RNF41, TRIM13, DDX39A, OLIG2, TRIB1, ZNF443, DENND4A, SF3B4, IRX5, RAMP3, FSTL3, CWC27, SAP18, SMNDC1, APBB3, TNIP1, IKZF1, TRIM22, HMG20B, HMG20A, KLF2, CITED2, PIAS3, IFITM3, RAPGEF3, NSA2, CD2BP2, EMG1, PPIH, TRIM38, CREB3, CARM1, SEMA4D, ZNF211, DEAF1, CHERP, ATG7, RPP30, RPP38, SIVA1, ERN2, USP16, TBL3, ERLIN1, HEXIM1, RBCK1, ARID3B, IVNS1ABP, TRIM16, TXNIP, DMRT2, KHDRBS1, FARS2, RRAGA, USP39, TBR1, RAI1, PHTF1, NUP50, AHCYL1, ZMYND11, ZBTB6, ZNF234, ZNF266, WDR4, ZNF273, ZNF275, ARID5A, WDR3, MALT1, BRD8, TXNL4A, PAPOLA, RNPS1, SRSF8, PRDX3, SF3A3, YWHAQ, CCDC85B, SNRNP27, VAX1, GTF2A1L, PIM2, ADRM1, WWP1, WWP2, DUS4L, SOX30, SNRNP35, HSF2BP, WDR5, NUPL2, RPP14, KRR1, PRDM7, PRDM5, CLASRP, ERLIN2, SOX21, PSIP1, WDHD1, STRAP, ZNF277, WBP4, DDX20, RPL35 |
2065 | GO:2000112 | 0.00 | 1.18 | 481.67 | 526 | 1326 | regulation of cellular macromolecule biosynthetic process | AARS, ABCA2, ABL1, ACO1, ACTL6A, ACVR1, ACVR2A, ADRB2, JAG1, AGTR2, AKT2, ALK, ALX3, ANXA3, BIRC2, XIAP, APP, AREG, PHOX2A, ARNT, ATM, ATOH1, BCL2, BMP1, BMP3, BMP8B, BMPR1A, BRDT, ZFP36L2, KLF9, BTF3, BTG1, BTK, CAMK4, CAMK2A, CBFB, CBL, CCNC, CCNE1, CCNH, CCNT1, CCNT2, CCT6A, CD3D, CD28, CD80, CD86, TNFSF8, CD81, CDK11B, CDC5L, CDC42, CDH1, CDK2, CDK4, CDK8, CDK9, CDX1, CEBPE, CENPB, CGA, CHD1, CHD2, CHD3, CHEK1, CHUK, CLU, COL1A1, CREBL2, CRX, CSNK2A1, CSNK2A2, CTH, CTNND2, DGKQ, DAZ1, DCN, DDX1, DDX6, DHFR, DIO2, DLX5, DLX6, DNM2, ARID3A, RCAN1, E2F2, E2F4, EBF1, ECM1, EDA, S1PR1, EEF2, EGR2, EGR3, EGR4, EIF2B1, EIF4A1, EIF4G1, EIF4G2, EIF5, EIF5A, ELAVL2, ELAVL1, ELK1, EMX1, EMX2, EPHA5, ERBB2, EYA4, ERCC3, ERCC6, ERG, ERN1, ESRRG, ETF1, ETS1, ETV4, ETV5, EVX1, EWSR1, EYA1, EYA2, EYA3, EZH1, F2R, F2RL1, FBN1, EFEMP1, FGF4, FGF7, FLI1, FSHB, NR5A2, NR5A1, FZD2, GALR1, GATA4, GCG, KAT2A, GDF9, GPC3, GOLGA2, GSC2, GTF2F1, GTF2I, GTF3A, BRF1, HCK, HEXB, HIP1, HIVEP2, ZBTB48, HLF, HLX, HMGN1, NR4A1, HMX2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD3, HOXD10, HOXD11, HOXD12, HSPB1, ICAM1, SP110, IGF1, IGF2, IHH, IL1A, IL10, IL15, IL17A, ILK, ING2, INS, INSIG1, IRF5, ITGA3, KIT, KRAS, AFF3, ABLIM1, LTF, LUM, EPCAM, SMAD6, SMAD9, MAZ, MEOX2, KITLG, ATXN3, AFF1, FOXO4, PPP1R12A, NRL, NTF3, NTRK1, NTRK3, OGG1, SIX6, ORC1, OTX1, OTX2, P2RY1, PCSK6, SERPINE1, PAM, PCK1, PCNA, PDE8A, PF4, PFDN1, PFN1, PGR, PPP1R8, PPP2R1A, PPP3R1, PRKAA1, PRKAR1A, PRKCI, PRKD1, PRKCZ, MAPK8, RELN, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PTAFR, PTEN, RAC1, RAD21, RAF1, RBBP6, RBL2, DPF2, RFX1, RFX2, RFXAP, RGS2, RLF, RNF6, RPL38, RPS4X, RPS6KA1, RPS6KB1, RPS6KB2, RRM2, RXRG, RYR2, S100A8, S100A9, S100A12, CCL21, TRAPPC2, SFSWAP, SGK1, SHC1, SLC9A1, SLC11A1, SMARCA1, SMARCD1, SMARCD3, SNAPC1, SNAPC2, SNAPC3, SOD2, SOX1, SOX12, SP1, SP4, SPIB, SSRP1, STAT2, STAT4, STAT5B, TAF2, TAF4B, TAF5, TAF6, TAF10, TAF13, TAL2, HNF1A, ZNF354A, TMF1, TMPO, TNFRSF1A, TNNI2, TOP2A, NR2C2, TRAF1, TRAF2, CCT3, TRIP6, TSC2, TULP3, TYMS, UBE2D2, UBE2L3, UBE3A, UCN, UCP1, USF1, VAV1, EIF4H, WNT1, WNT2, ZFP37, ZFPL1, ZIC1, ZNF3, ZNF711, ZNF7, CNBP, ZNF708, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZSCAN21, ZNF41, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF99, ZNF124, ZNF132, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, TRIM25, ZBTB17, ZNF155, VEZF1, ZNF180, ZNF207, ZNF223, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, ZXDA, PRDM2, CSDE1, PAX8, FZD5, BRPF1, ARHGEF5, ZNF212, BRD3, CSRP3, FOSL1, FGF23, ANP32A, ZNF239, DPF1, CHAF1B, USP9Y, PICALM, FZD4, FZD7, DYRK2, CUL2, FOXN1, SMARCA5, OGT, ITGA8, IKBKG, IKBKAP, GAS7, CAMK1, PIR, BLZF1, KHSRP, STK16, RGS20, RUVBL1, KLF7, CDK13, RFXANK, CHRD, DYNLL1, EIF3G, EIF3J, EIF4G3, TRADD, EDF1, RIPK1, RIPK2, CFLAR, TSC22D1, KAT2B, CDC123, EIF2B2, BUD31, CPNE1, PHOX2B, USP13, RPS6KA4, TNFSF18, BAZ1B, PDLIM1, DYRK1B, CTDP1, ARHGEF2, SLC33A1, CCPG1, ITGB1BP1, ZNF235, HMGN3, CER1, CIAO1, ZRANB2, ZNF264, FHL5, ONECUT2, LITAF, TBPL1, SOX13, RBM39, RNF14, ABCG1, ZNF592, ZNF516, EIF5B, VGLL4, BZW1, ZNF646, SETD1A, ZFYVE16, MAML1, TSC22D2, RB1CC1, ARHGEF11, ZBTB24, ZNF518A, EPM2AIP1, SUPT7L, RNF10, ZBTB5, RBM8A, RBX1, DMTF1, CASP8AP2, PREB, TRAP1, RNF41, TRIM13, EIF1, ZNF443, DENND4A, IRX5, FSTL3, SAP18, EIF1B, APBB3, TNIP1, TRIM22, HMG20B, KLF2, PIAS3, RAPGEF3, RBM14, PPIE, SLC30A9, TRIM38, EIF3M, CREB3, CARM1, ZNF211, ARFGEF1, CCT7, SORBS1, USP16, ERLIN1, ARID3B, TRIM16, DMRT2, TBR1, RAI1, PHTF1, ZBTB6, ZNF266, ZNF273, ZNF275, RUVBL2, MALT1, BRD8, PRDX3, ASCC3, COPS5, GTF2A1L, PIM2, SOX30, WDR5, PRDM7, KAT7, ERLIN2, SOX21, PSIP1, ZNF277, SUPT16H |
2066 | GO:0043170 | 0.05 | 1.15 | 240.15 | 260 | 723 | macromolecule metabolic process | ABCA3, ACADVL, ACP1, ACY1, ADD1, ADH5, ADM, AGA, ALB, AMHR2, APOH, KLK3, TRIM23, ARSA, STS, ARSD, ARSE, ARSF, ASL, ASNA1, AXL, BCHE, OPN1SW, BCR, BGLAP, BHMT, BLK, C1QA, C1QB, C1QC, C1S, CAPN5, CALCR, CAPN6, CASP4, CASP5, CASP6, CD9, CDK3, CHRM1, CHRM3, TBCB, CLCA1, CCR5, CPA1, CPD, CR2, CSNK1G2, CSNK1G3, CTRB1, DCX, DMBT1, DNM1, DPP4, DPP6, DSP, PHC1, PHC2, EPHB2, EPHB3, EVPL, F7, F10, FCER1G, FCN2, FKBP3, FKBP5, FYB, GAD1, GAK, BLOC1S1, OPN1MW, GFER, GGCX, GGT7, GLE1, GP9, GRK6, GUCY2C, GUCY2F, GZMH, GUCY2D, CFHR1, HLCS, HMBS, HP, AGFG1, HSPA9, IAPP, IGFALS, IGFBP2, IGFBP6, IL1RAP, IL12RB2, INSRR, KCNH2, KLK1, KRT1, LIPE, LTA4H, MAN2B1, MDH2, MEP1A, MEP1B, NRTN, OLR1, OXTR, P4HA1, PAH, PAPPA, PCSK5, CDK17, PDK4, PEX12, PFDN2, CDK14, PHEX, PIK3C3, PPIB, PRCP, PREP, PRKX, PROC, PSKH1, PTPN4, PTPN7, PTPN13, PTPRD, PTPRE, PTPRH, PTPRM, PTPRN, PTPRN2, PTPRS, RAB3B, RAB5A, RAB6A, RABGGTA, RABGGTB, RANGAP1, OPN1LW, RGR, RNPEP, SBF1, SFTPB, SHMT2, SLC34A1, SPRR1B, SPRR2A, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3, SRMS, ST14, CDKL5, SULT1A3, TBCA, TBCD, TBCE, TMPRSS2, TPSAB1, TSHB, TUBA4A, TUBA3C, TYRO3, UBE2E2, UQCRC1, UQCRC2, VBP1, VRK1, WEE1, TUBA1A, SCG2, CUBN, UBL4A, TPST2, TPST1, PPM1D, CDC14A, TNK1, ADAM19, RIOK3, DYRK4, CDKL1, GGH, PROZ, P4HA2, KALRN, CDKL2, RHBDL1, PAPSS2, PAPSS1, ATP6V0D1, PCSK7, NUMBL, STK17B, STK17A, ZFYVE9, TMPRSS11D, ARHGEF6, ADAMTS4, ADAMTS1, RAB3D, CDC42BPB, PREPL, KLK4, AATK, SNCAIP, CLCA2, TTLL4, ADAMTSL2, TOMM20, SCRN1, SPOCK2, DNAJC6, ZC3H11A, JOSD1, HS3ST4, SH2D3C, SH2D3A, UBA2, SAE1, DPP3, COL4A3BP, SGK2, PDIA6, ABI2, CALCRL, SPEG, TRAIP, BCKDK, UBAC1, UBE2E3, NXF1, PRDX4, ARFGEF2, SLC34A2, STAMBP, EXOC5, RRH, CORIN, CAPN9, SLC26A1, ADAM28, AFG3L2, PRSS21, PDIA5, CKAP4, KLK11, KDELR3, RAB31, PTPN21, CIT, PTPRT, CAPN11, CAPN10, FICD, SEC63 |