| GOBPID | Pvalue | OddsRatio | ExpCount | Count | Size | Term | Genes |
1 | GO:0030199 | 0.00 | Inf | 6.26 | 15 | 15 | collagen fibril organization | ANXA2, SERPINH1, COL1A1, COL2A1, COL3A1, COL5A1, COL5A2, COL11A1, COL12A1, LUM, DDR2, P4HA1, COL14A1, ADAMTS3, ADAMTS2 |
2 | GO:0043279 | 0.00 | Inf | 5.81 | 14 | 14 | response to alkaloid | ADA, BCHE, EDNRA, FGA, HIF1A, IL1B, PPP2R2A, PPP5C, PRKCE, PRKCG, TAC1, UQCRC1, PEA15, TMED10 |
3 | GO:0034698 | 0.00 | Inf | 5.84 | 14 | 14 | response to gonadotropin | ASNS, CTSV, GATA4, GATA6, GJB2, HMGCS1, ICAM1, ITGA3, ITGB1, PAWR, SLC5A5, SRD5A1, STAR, PAX8 |
4 | GO:0030155 | 0.00 | Inf | 5.29 | 13 | 13 | regulation of cell adhesion | S1PR1, ICAM1, LAMA3, LAMA4, LAMA5, PPP1R12A, SERPINI1, PPP2R1A, PRKX, SOX9, SRF, CYTIP, NUAK1 |
5 | GO:0007188 | 0.00 | Inf | 4.98 | 12 | 12 | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | AVPR2, CCR3, CNR1, FPR1, GCG, GCGR, GNAT1, GNAT2, PRKACB, PTGER4, GLP2R, WASF2 |
6 | GO:0033189 | 0.00 | Inf | 5.01 | 12 | 12 | response to vitamin A | ARG1, CAT, DNMT1, DNMT3A, DNMT3B, GATA4, RARA, RXRA, SLC34A1, TSHB, TYMS, ALDH1A2 |
7 | GO:0042476 | 0.00 | Inf | 4.58 | 11 | 11 | odontogenesis | AQP1, AQP5, AQP6, BGLAP, COL1A1, PAM, SDC1, TUFT1, TWIST1, ZNF22, ADAMTS1 |
8 | GO:0032303 | 0.00 | Inf | 4.59 | 11 | 11 | regulation of icosanoid secretion | AGTR2, ACSL4, IL1B, NTSR1, OXT, P2RX4, P2RX7, P2RY2, SYK, CYP4F2, TNFSF11 |
9 | GO:0033197 | 0.00 | Inf | 4.59 | 11 | 11 | response to vitamin E | ADA, ALAD, ARG1, CCND1, CAT, CCNE1, COL1A1, HMGCS1, PAWR, EIF2AK2, BECN1 |
10 | GO:0097296 | 0.00 | Inf | 4.59 | 11 | 11 | activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | BAX, CASP8, CD14, SMAD3, TRAF2, TRADD, RIPK1, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR |
11 | GO:0036092 | 0.00 | Inf | 4.17 | 10 | 10 | phosphatidylinositol-3-phosphate biosynthetic process | ATM, INPP4A, PIK3C2A, PIK3C2B, PIK3C3, PIK3CB, PIK3CG, PIK3R3, INPP4B, FIG4 |
12 | GO:0007187 | 0.00 | Inf | 3.73 | 9 | 9 | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | AGTR2, ANXA1, CCR1, CNR2, GPR1, XCR1, HRH2, SSTR3, VIPR1 |
13 | GO:0050927 | 0.00 | Inf | 3.75 | 9 | 9 | positive regulation of positive chemotaxis | AKT2, S1PR1, F2RL1, F3, F7, ITGA2, KDR, SMAD3, NTRK3 |
14 | GO:0042026 | 0.00 | Inf | 3.76 | 9 | 9 | protein refolding | BAG1, DNAJB2, HSPA6, HSPA8, HSP90AA1, PDCL, SNRNP70, DNAJC7, BAG5 |
15 | GO:0015698 | 0.00 | Inf | 3.33 | 8 | 8 | inorganic anion transport | AQP6, ASNA1, CRY2, ENPP1, SFRP4, SLC5A5, SLC11A1, FGF23 |
16 | GO:0098900 | 0.00 | Inf | 3.33 | 8 | 8 | regulation of action potential | IFNG, KCNJ2, NTSR1, PAWR, PTPN3, SCN5A, SLC9A1, TAC1 |
17 | GO:2000107 | 0.00 | Inf | 3.34 | 8 | 8 | negative regulation of leukocyte apoptotic process | AXL, FCER1G, GAS6, HCLS1, ITPKB, KITLG, CCL21, ST6GAL1 |
18 | GO:0003085 | 0.00 | Inf | 3.34 | 8 | 8 | negative regulation of systemic arterial blood pressure | ADRB2, AGTR2, BBS4, BMPR2, NTSR1, PRCP, SOD2, KCNK6 |
19 | GO:0014002 | 0.00 | Inf | 3.34 | 8 | 8 | astrocyte development | CDK6, GFAP, KRAS, S100A8, S100A9, VIM, EIF2B5, TSPAN2 |
20 | GO:0030656 | 0.00 | Inf | 3.34 | 8 | 8 | regulation of vitamin metabolic process | CYP27B1, GFI1, IFNG, IL1B, SNAI2, SNAI1, VDR, AKR1C3 |
21 | GO:0031581 | 0.00 | Inf | 3.34 | 8 | 8 | hemidesmosome assembly | DST, CD151, COL17A1, ITGA6, ITGB4, KRT5, KRT14, LAMA3 |
22 | GO:0042340 | 0.00 | Inf | 3.34 | 8 | 8 | keratan sulfate catabolic process | GALNS, GLB1, HEXA, HEXB, LUM, OMD, OGN, KERA |
23 | GO:0055093 | 0.00 | Inf | 3.34 | 8 | 8 | response to hyperoxia | BNIP3, CAT, CDK4, CDKN1A, COL1A1, DNMT3B, KCNA5, ATG7 |
24 | GO:0070307 | 0.00 | Inf | 3.34 | 8 | 8 | lens fiber cell development | BFSP1, CRYGB, EPHA2, FGFR3, PROX1, TMOD1, VIM, BFSP2 |
25 | GO:0097421 | 0.00 | Inf | 3.34 | 8 | 8 | liver regeneration | ADRB2, FGA, KLKB1, PTPN3, RAP1A, SRSF5, RGN, RAPGEF3 |
26 | GO:1902991 | 0.00 | Inf | 3.34 | 8 | 8 | regulation of amyloid precursor protein catabolic process | CLU, FLOT2, SORL1, PICALM, HAP1, ABCA7, OLFM1, TMED10 |
27 | GO:2000193 | 0.00 | Inf | 3.34 | 8 | 8 | positive regulation of fatty acid transport | IL1B, NTSR1, OXT, P2RX4, P2RX7, P2RY2, CYP4F2, TNFSF11 |
28 | GO:0022602 | 0.00 | Inf | 2.91 | 7 | 7 | ovulation cycle process | KISS1, PAM, PGR, SLIT3, NRIP1, SLIT2, ADAMTS1 |
29 | GO:0090075 | 0.00 | Inf | 2.92 | 7 | 7 | relaxation of muscle | ADORA1, ATP2A1, P2RY1, PAWR, PRKG1, SLN, SOD1 |
30 | GO:0031000 | 0.00 | Inf | 2.92 | 7 | 7 | response to caffeine | DHODH, DNMT1, DNMT3B, GNAL, IGF1, PRKAA1, SDC2 |
31 | GO:0001553 | 0.00 | Inf | 2.92 | 7 | 7 | luteinization | CAPN5, NR5A1, GDF9, PTPRN, STAT5B, FZD4, SGPL1 |
32 | GO:0006107 | 0.00 | Inf | 2.92 | 7 | 7 | oxaloacetate metabolic process | ACLY, GOT1, GOT2, MDH1, MDH2, PCK1, STAT5B |
33 | GO:0006538 | 0.00 | Inf | 2.92 | 7 | 7 | glutamate catabolic process | GAD1, GAD2, GLUD1, GLUD2, GLUL, GOT1, GOT2 |
34 | GO:0017085 | 0.00 | Inf | 2.92 | 7 | 7 | response to insecticide | CCNB1, CPOX, DDC, FECH, SCN2B, SCN3A, STAR |
35 | GO:0032373 | 0.00 | Inf | 2.92 | 7 | 7 | positive regulation of sterol transport | ABCA1, PTCH1, SCP2, NR1H2, LIPG, ABCG1, ABCA7 |
36 | GO:0033129 | 0.00 | Inf | 2.92 | 7 | 7 | positive regulation of histone phosphorylation | ATM, CCNB1, CDK9, IL1B, MAPK3, RPS6KA4, RPS6KA5 |
37 | GO:0034616 | 0.00 | Inf | 2.92 | 7 | 7 | response to laminar fluid shear stress | ABCA1, ASS1, ETS1, SMAD6, SMAD7, KLF4, KLF2 |
38 | GO:0035025 | 0.00 | Inf | 2.92 | 7 | 7 | positive regulation of Rho protein signal transduction | APOA1, COL3A1, LPAR1, F2R, F2RL1, RAC1, GPR55 |
39 | GO:0035457 | 0.00 | Inf | 2.92 | 7 | 7 | cellular response to interferon-alpha | AXL, ENTPD2, GAS6, GATA3, IFIT3, OAS1, STAR |
40 | GO:0043206 | 0.00 | Inf | 2.92 | 7 | 7 | extracellular fibril organization | COL3A1, COL5A1, ILK, LTBP2, SNCA, ADAMTS3, B4GALT7 |
41 | GO:0043306 | 0.00 | Inf | 2.92 | 7 | 7 | positive regulation of mast cell degranulation | FCER1A, FCER1G, FGR, IL13, SYK, VAMP8, GAB2 |
42 | GO:0043374 | 0.00 | Inf | 2.92 | 7 | 7 | CD8-positive, alpha-beta T cell differentiation | BCL2, TNFSF8, IFNG, IRF1, PAX1, SATB1, EOMES |
43 | GO:0050930 | 0.00 | Inf | 2.92 | 7 | 7 | induction of positive chemotaxis | NTF3, PRKCA, VEGFA, VEGFB, VEGFC, SCG2, CREB3 |
44 | GO:0051597 | 0.00 | Inf | 2.92 | 7 | 7 | response to methylmercury | ALAD, ARG1, CCNE1, CPOX, FECH, HMBS, S100B |
45 | GO:0060442 | 0.00 | Inf | 2.92 | 7 | 7 | branching involved in prostate gland morphogenesis | BMP4, CD44, ESR1, IGF1, RXRA, SHH, FEM1B |
46 | GO:0072012 | 0.00 | Inf | 2.92 | 7 | 7 | glomerulus vasculature development | ACTA2, ANGPT1, ANGPT2, AQP1, BMP4, HES1, SERPINB7 |
47 | GO:0097531 | 0.00 | Inf | 2.92 | 7 | 7 | mast cell migration | KIT, RAC1, RAC2, STAT5B, VEGFA, VEGFB, VEGFC |
48 | GO:0072001 | 0.00 | Inf | 2.48 | 6 | 6 | renal system development | EMX2, ITGA6, ITGB4, TP63, IFT140, SEC63 |
49 | GO:0002455 | 0.01 | Inf | 2.50 | 6 | 6 | humoral immune response mediated by circulating immunoglobulin | BCL3, FCER2, HPX, PTPN6, ZP3, EXO1 |
50 | GO:0003156 | 0.01 | Inf | 2.50 | 6 | 6 | regulation of organ formation | EYA1, HES1, ISL1, SHH, HAND2, CITED2 |
51 | GO:0032964 | 0.01 | Inf | 2.50 | 6 | 6 | collagen biosynthetic process | ARG1, SERPINH1, COL1A1, COL5A1, ADAMTS3, TRAM2 |
52 | GO:0001867 | 0.01 | Inf | 2.50 | 6 | 6 | complement activation, lectin pathway | A2M, SERPING1, FCN1, FCN2, KRT1, FCN3 |
53 | GO:0002863 | 0.01 | Inf | 2.50 | 6 | 6 | positive regulation of inflammatory response to antigenic stimulus | C3, CD28, CNR1, FCER1A, FCER1G, ZP3 |
54 | GO:0006559 | 0.01 | Inf | 2.50 | 6 | 6 | L-phenylalanine catabolic process | CCBL1, GSTZ1, HPD, PAH, QDPR, TAT |
55 | GO:0006782 | 0.01 | Inf | 2.50 | 6 | 6 | protoporphyrinogen IX biosynthetic process | ALAD, ALAS1, ALAS2, CPOX, HMBS, UROS |
56 | GO:0010885 | 0.01 | Inf | 2.50 | 6 | 6 | regulation of cholesterol storage | ABCA1, CD36, SCARB1, NR1H2, ABCG1, EHD1 |
57 | GO:0018119 | 0.01 | Inf | 2.50 | 6 | 6 | peptidyl-cysteine S-nitrosylation | ADH5, ACE, GAPDH, S100A8, S100A9, SNTA1 |
58 | GO:0031284 | 0.01 | Inf | 2.50 | 6 | 6 | positive regulation of guanylate cyclase activity | GUCA1A, GUCA1B, GUCA2A, GUCA2B, RCVRN, GUCA1C |
59 | GO:0032057 | 0.01 | Inf | 2.50 | 6 | 6 | negative regulation of translational initiation in response to stress | ATF4, EIF2S1, EIF2B4, EIF2B3, EIF2B5, EIF2AK3 |
60 | GO:0032099 | 0.01 | Inf | 2.50 | 6 | 6 | negative regulation of appetite | BBS2, BBS4, CCK, GCG, UCN, CARTPT |
61 | GO:0032261 | 0.01 | Inf | 2.50 | 6 | 6 | purine nucleotide salvage | ADA, ADK, AMPD1, AMPD2, APRT, HPRT1 |
62 | GO:0032308 | 0.01 | Inf | 2.50 | 6 | 6 | positive regulation of prostaglandin secretion | IL1B, OXT, P2RX4, P2RX7, P2RY2, TNFSF11 |
63 | GO:0032695 | 0.01 | Inf | 2.50 | 6 | 6 | negative regulation of interleukin-12 production | ACP5, C1QBP, CMKLR1, IL10, TNFRSF9, SLAMF1 |
64 | GO:0032769 | 0.01 | Inf | 2.50 | 6 | 6 | negative regulation of monooxygenase activity | CAV3, CNR1, CNR2, CYP27B1, GFI1, SNCA |
65 | GO:0032909 | 0.01 | Inf | 2.50 | 6 | 6 | regulation of transforming growth factor beta2 production | CDH3, ATF2, GATA6, HIF1A, SMAD3, WNT11 |
66 | GO:0033033 | 0.01 | Inf | 2.50 | 6 | 6 | negative regulation of myeloid cell apoptotic process | APOH, BCL2, FCER1G, ITPKB, KITLG, ST6GAL1 |
67 | GO:0035234 | 0.01 | Inf | 2.50 | 6 | 6 | ectopic germ cell programmed cell death | BAX, CASP5, IL1A, IL1B, KIT, KITLG |
68 | GO:0038180 | 0.01 | Inf | 2.50 | 6 | 6 | nerve growth factor signaling pathway | RAPGEF1, NTRK1, RAP1A, SORT1, RAPGEF2, CORO1A |
69 | GO:0048664 | 0.01 | Inf | 2.50 | 6 | 6 | neuron fate determination | ATOH1, CDC42, HES1, OTX2, PRRX1, WNT1 |
70 | GO:0051481 | 0.01 | Inf | 2.50 | 6 | 6 | negative regulation of cytosolic calcium ion concentration | ATP1A2, GTF2I, HRC, KCNA5, KCNK3, SLC8A1 |
71 | GO:0051901 | 0.01 | Inf | 2.50 | 6 | 6 | positive regulation of mitochondrial depolarization | ALOX12, TSPO, CCK, DCN, KDR, P2RX7 |
72 | GO:0070257 | 0.01 | Inf | 2.50 | 6 | 6 | positive regulation of mucus secretion | CYBA, P2RY2, PRKCE, PTGER4, ATG5, ATG7 |
73 | GO:0071276 | 0.01 | Inf | 2.50 | 6 | 6 | cellular response to cadmium ion | CYP1A2, OGG1, PPP5C, SOD1, STAR, AKR1C3 |
74 | GO:0071313 | 0.01 | Inf | 2.50 | 6 | 6 | cellular response to caffeine | CASQ2, GSTM2, RYR1, RYR2, RYR3, SLC8A1 |
75 | GO:0086016 | 0.01 | Inf | 2.50 | 6 | 6 | AV node cell action potential | CXADR, GJA5, RYR2, SCN4B, SCN5A, SCN10A |
76 | GO:0086067 | 0.01 | Inf | 2.50 | 6 | 6 | AV node cell to bundle of His cell communication | CXADR, GJA5, RYR2, SCN4B, SCN5A, SCN10A |
77 | GO:0090009 | 0.01 | Inf | 2.50 | 6 | 6 | primitive streak formation | ETS2, HHEX, FOXA2, OTX2, SRF, T |
78 | GO:1902221 | 0.01 | Inf | 2.50 | 6 | 6 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process | CCBL1, GSTZ1, HPD, PAH, QDPR, TAT |
79 | GO:2000323 | 0.01 | Inf | 2.50 | 6 | 6 | negative regulation of glucocorticoid receptor signaling pathway | ARNTL, CRY1, CRY2, PER1, PHB, CLOCK |
80 | GO:1903522 | 0.01 | Inf | 2.05 | 5 | 5 | regulation of blood circulation | ADCY6, CRP, HMGCR, P2RY1, P2RY2 |
81 | GO:0031960 | 0.01 | Inf | 2.06 | 5 | 5 | response to corticosteroid | COL1A1, CTGF, AKR1C3, AIFM1, SOX30 |
82 | GO:1903039 | 0.01 | Inf | 2.07 | 5 | 5 | positive regulation of leukocyte cell-cell adhesion | CD44, HAS2, ITGA4, PAWR, PTAFR |
83 | GO:0050870 | 0.01 | Inf | 2.07 | 5 | 5 | positive regulation of T cell activation | FLOT2, TRAF2, TNFSF11, BCL10, MALT1 |
84 | GO:0010863 | 0.01 | Inf | 2.08 | 5 | 5 | positive regulation of phospholipase C activity | ABL2, ESR1, FLT1, KIT, PTAFR |
85 | GO:0044003 | 0.01 | Inf | 2.08 | 5 | 5 | modification by symbiont of host morphology or physiology | ALB, APCS, ITGAV, SERPINB9, TNIP1 |
86 | GO:0003044 | 0.01 | Inf | 2.08 | 5 | 5 | regulation of systemic arterial blood pressure mediated by a chemical signal | ADRA1B, ADRB2, PDE4D, SLC2A5, SOD2 |
87 | GO:0051932 | 0.01 | Inf | 2.08 | 5 | 5 | synaptic transmission, GABAergic | CLCN3, DNM1, GABRB2, RAC1, RAC3 |
88 | GO:0072378 | 0.01 | Inf | 2.08 | 5 | 5 | blood coagulation, fibrin clot formation | F3, F7, FBLN1, FGA, FGG |
89 | GO:0086002 | 0.01 | Inf | 2.08 | 5 | 5 | cardiac muscle cell action potential involved in contraction | KCNA5, KCNJ2, SCN2B, SCN4B, NUP155 |
90 | GO:0035455 | 0.01 | Inf | 2.08 | 5 | 5 | response to interferon-alpha | ADAR, BST2, EIF2AK2, IFITM3, IFITM2 |
91 | GO:0060351 | 0.01 | Inf | 2.08 | 5 | 5 | cartilage development involved in endochondral bone morphogenesis | SERPINH1, COL1A1, COL2A1, HOXD11, SOX9 |
92 | GO:0021602 | 0.01 | Inf | 2.09 | 5 | 5 | cranial nerve morphogenesis | PHOX2A, CHRNB2, HOXD3, ATP8B1, SIX1 |
93 | GO:0043084 | 0.01 | Inf | 2.09 | 5 | 5 | penile erection | ACVR2A, ADA, AVP, CNR1, EDNRA |
94 | GO:0032891 | 0.01 | Inf | 2.09 | 5 | 5 | negative regulation of organic acid transport | ABAT, ADORA1, IL1B, TRH, HRH3 |
95 | GO:0045064 | 0.01 | Inf | 2.09 | 5 | 5 | T-helper 2 cell differentiation | ANXA1, BCL3, GATA3, HLX, BATF |
96 | GO:0002328 | 0.01 | Inf | 2.09 | 5 | 5 | pro-B cell differentiation | FLT3, HES1, SOS1, SOS2, SOX4 |
97 | GO:0003211 | 0.01 | Inf | 2.09 | 5 | 5 | cardiac ventricle formation | SMARCD3, SOX4, SOX11, HAND1, HAND2 |
98 | GO:0003263 | 0.01 | Inf | 2.09 | 5 | 5 | cardioblast proliferation | EYA1, HES1, ISL1, SIX1, HAND2 |
99 | GO:0003266 | 0.01 | Inf | 2.09 | 5 | 5 | regulation of secondary heart field cardioblast proliferation | EYA1, HES1, ISL1, SIX1, HAND2 |
100 | GO:0007021 | 0.01 | Inf | 2.09 | 5 | 5 | tubulin complex assembly | ARL2, CRYAB, TBCA, TBCD, VBP1 |
101 | GO:0007084 | 0.01 | Inf | 2.09 | 5 | 5 | mitotic nuclear envelope reassembly | EMD, PPP2R1A, PPP2R2A, VRK1, BANF1 |
102 | GO:0007185 | 0.01 | Inf | 2.09 | 5 | 5 | transmembrane receptor protein tyrosine phosphatase signaling pathway | PTN, PTPRD, PTPRE, TRIO, PTPRU |
103 | GO:0007341 | 0.01 | Inf | 2.09 | 5 | 5 | penetration of zona pellucida | B4GALT1, HEXB, SMCP, T, TNP2 |
104 | GO:0009629 | 0.01 | Inf | 2.09 | 5 | 5 | response to gravity | BGLAP, CBLB, PTAFR, SPARC, FOSL1 |
105 | GO:0010269 | 0.01 | Inf | 2.09 | 5 | 5 | response to selenium ion | ALAD, ARG1, GIP, GPX1, RXRA |
106 | GO:0010763 | 0.01 | Inf | 2.09 | 5 | 5 | positive regulation of fibroblast migration | DDR2, PRKCE, SLC8A1, ARHGEF7, BAG4 |
107 | GO:0010875 | 0.01 | Inf | 2.09 | 5 | 5 | positive regulation of cholesterol efflux | ABCA1, PTCH1, NR1H2, ABCG1, ABCA7 |
108 | GO:0014012 | 0.01 | Inf | 2.09 | 5 | 5 | peripheral nervous system axon regeneration | APOA1, TSPO, CALU, TNC, CHST3 |
109 | GO:0016540 | 0.01 | Inf | 2.09 | 5 | 5 | protein autoprocessing | CTSE, CTSV, F12, KLK6, TMPRSS2 |
110 | GO:0019373 | 0.01 | Inf | 2.09 | 5 | 5 | epoxygenase P450 pathway | CYP1A2, CYP2A6, CYP2A13, CYP2F1, CYP4F2 |
111 | GO:0021796 | 0.01 | Inf | 2.09 | 5 | 5 | cerebral cortex regionalization | EMX1, EMX2, TRA2B, NR2F1, EOMES |
112 | GO:0032060 | 0.01 | Inf | 2.09 | 5 | 5 | bleb assembly | LPAR1, EMP1, EMP2, EMP3, P2RX7 |
113 | GO:0032222 | 0.01 | Inf | 2.09 | 5 | 5 | regulation of synaptic transmission, cholinergic | ACHE, CACNA1A, IFNG, TAC1, TACR2 |
114 | GO:0032536 | 0.01 | Inf | 2.09 | 5 | 5 | regulation of cell projection size | CNTN2, VIL1, EZR, XK, TWF2 |
115 | GO:0033327 | 0.01 | Inf | 2.09 | 5 | 5 | Leydig cell differentiation | NR0B1, CCND1, HSD17B10, TMF1, SGPL1 |
116 | GO:0033591 | 0.01 | Inf | 2.09 | 5 | 5 | response to L-ascorbic acid | ACP5, CAT, IL1B, ITGA2, SPARC |
117 | GO:0034379 | 0.01 | Inf | 2.09 | 5 | 5 | very-low-density lipoprotein particle assembly | ARF1, ACSL3, FECH, SOAT2, DGAT1 |
118 | GO:0035878 | 0.01 | Inf | 2.09 | 5 | 5 | nail development | ITGA6, ITGB4, KRT84, FZD6, FOXN1 |
119 | GO:0042538 | 0.01 | Inf | 2.09 | 5 | 5 | hyperosmotic salinity response | AQP1, AVP, OXT, SLC12A1, TACR3 |
120 | GO:0042760 | 0.01 | Inf | 2.09 | 5 | 5 | very long-chain fatty acid catabolic process | ACADVL, ABCD1, ABCD3, SLC27A4, SLC27A2 |
121 | GO:0044539 | 0.01 | Inf | 2.09 | 5 | 5 | long-chain fatty acid import | CD36, ACSL1, ACSL3, SLC27A4, SLC27A2 |
122 | GO:0045990 | 0.01 | Inf | 2.09 | 5 | 5 | carbon catabolite regulation of transcription | FOXA2, CHMP1A, SRF, USF1, USF2 |
123 | GO:0046060 | 0.01 | Inf | 2.09 | 5 | 5 | dATP metabolic process | ADA, ADK, AK2, GUK1, NUDT1 |
124 | GO:0046629 | 0.01 | Inf | 2.09 | 5 | 5 | gamma-delta T cell activation | CXADR, EGR3, STAT5B, SYK, SOX13 |
125 | GO:0048050 | 0.01 | Inf | 2.09 | 5 | 5 | post-embryonic eye morphogenesis | BAX, FBN1, EFEMP1, HMGN1, KDR |
126 | GO:0051769 | 0.01 | Inf | 2.09 | 5 | 5 | regulation of nitric-oxide synthase biosynthetic process | FCER2, KDR, PGGT1B, PTGER4, CCL20 |
127 | GO:0051971 | 0.01 | Inf | 2.09 | 5 | 5 | positive regulation of transmission of nerve impulse | CHRNB4, ITGA2, PAWR, TNR, CARTPT |
128 | GO:0060174 | 0.01 | Inf | 2.09 | 5 | 5 | limb bud formation | COL2A1, SHH, SOX4, SOX9, SOX11 |
129 | GO:0060263 | 0.01 | Inf | 2.09 | 5 | 5 | regulation of respiratory burst | APOH, INS, RAC1, RAC2, RPS19 |
130 | GO:0060391 | 0.01 | Inf | 2.09 | 5 | 5 | positive regulation of SMAD protein import into nucleus | BMP4, BMP6, BMPR1A, DAB2, RBPMS |
131 | GO:0060536 | 0.01 | Inf | 2.09 | 5 | 5 | cartilage morphogenesis | SNAI2, SNAI1, STC1, HAND1, HAND2 |
132 | GO:0060558 | 0.01 | Inf | 2.09 | 5 | 5 | regulation of calcidiol 1-monooxygenase activity | CYP27B1, GFI1, IFNG, IL1B, VDR |
133 | GO:0070459 | 0.01 | Inf | 2.09 | 5 | 5 | prolactin secretion | ABAT, ANXA1, ANXA5, TACR2, VIP |
134 | GO:0071321 | 0.01 | Inf | 2.09 | 5 | 5 | cellular response to cGMP | HCN2, PDE3A, SLC6A4, RAPGEF2, HCN4 |
135 | GO:1900376 | 0.01 | Inf | 2.09 | 5 | 5 | regulation of secondary metabolite biosynthetic process | ASIP, CDH3, TYRP1, RAPGEF2, ZEB2 |
136 | GO:1901894 | 0.01 | Inf | 2.09 | 5 | 5 | regulation of calcium-transporting ATPase activity | PLN, RYR2, SLN, SUMO1, RGN |
137 | GO:1901897 | 0.01 | Inf | 2.09 | 5 | 5 | regulation of relaxation of cardiac muscle | CAMK2G, HRC, PDE4B, PDE4D, PLN |
138 | GO:1902337 | 0.01 | Inf | 2.09 | 5 | 5 | regulation of apoptotic process involved in morphogenesis | BAX, B4GALT1, PAX2, VDR, PAX8 |
139 | GO:1902430 | 0.01 | Inf | 2.09 | 5 | 5 | negative regulation of beta-amyloid formation | CLU, SORL1, HAP1, ABCA7, OLFM1 |
140 | GO:1903140 | 0.01 | Inf | 2.09 | 5 | 5 | regulation of establishment of endothelial barrier | S1PR3, IL1B, PROC, TNFRSF1A, S1PR2 |
141 | GO:1903236 | 0.01 | Inf | 2.09 | 5 | 5 | regulation of leukocyte tethering or rolling | ITGA4, PAWR, PTAFR, CCL21, CCL25 |
142 | GO:2000074 | 0.01 | Inf | 2.09 | 5 | 5 | regulation of type B pancreatic cell development | ARNTL, BAD, RFX3, RHEB, CLOCK |
143 | GO:2000188 | 0.01 | Inf | 2.09 | 5 | 5 | regulation of cholesterol homeostasis | ACOX1, FGFR4, NR1H2, NR1D1, SEC24A |
144 | GO:2000271 | 0.01 | Inf | 2.09 | 5 | 5 | positive regulation of fibroblast apoptotic process | BTG1, TP63, STK17B, STK17A, BCL2L11 |
145 | GO:2001054 | 0.01 | Inf | 2.09 | 5 | 5 | negative regulation of mesenchymal cell apoptotic process | HIF1A, PAX2, SHH, SOX9, PAX8 |
146 | GO:0006695 | 0.00 | 25.30 | 7.92 | 18 | 19 | cholesterol biosynthetic process | ACLY, APOA1, APOA4, CFTR, CYP51A1, DHCR24, CYB5R3, FDFT1, FDPS, HMGCR, HMGCS1, HMGCS2, INSIG1, SQLE, CNBP, GGPS1, ACAA2, EBP |
147 | GO:0032374 | 0.00 | 19.62 | 6.26 | 14 | 15 | regulation of cholesterol transport | ABCA1, ABCA2, APOA1, APOA4, APOC2, TSPO, CETP, PTCH1, SCP2, SHH, NR1H2, LIPG, ABCG1, ABCA7 |
148 | GO:0043278 | 0.00 | 19.62 | 6.26 | 14 | 15 | response to morphine | ADA, ADRA1B, CNR1, EDNRA, FGA, IL1B, PENK, PPP2R2A, PPP5C, PRKCE, PRKCG, TAC1, TACR3, PEA15 |
149 | GO:0045653 | 0.00 | 18.21 | 5.84 | 13 | 14 | negative regulation of megakaryocyte differentiation | GABPA, PRMT1, PF4, HIST1H4I, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L |
150 | GO:0071542 | 0.00 | 18.21 | 5.84 | 13 | 14 | dopaminergic neuron differentiation | PHOX2A, EN1, FGF8, HIF1A, FOXA2, OTX2, RAC1, RYK, SHH, VEGFA, WNT1, WNT2, PHOX2B |
151 | GO:0031281 | 0.00 | 16.88 | 10.84 | 24 | 26 | positive regulation of cyclase activity | ADCYAP1R1, ADORA2A, ADRB2, AVPR2, CALCR, CALM3, EDNRA, FSHR, GHRHR, GLP1R, GNAL, GNAS, NTRK1, NTRK2, P2RY11, PRKCA, MAPK3, MAPK8, RAF1, VIP, VIPR2, WFS1, CAP2, CAP1 |
152 | GO:0001991 | 0.00 | 16.80 | 5.43 | 12 | 13 | regulation of systemic arterial blood pressure by circulatory renin-angiotensin | AGTR2, ANPEP, CPA3, CTSG, CTSZ, ACE, ENPEP, F2R, F2RL1, GJA5, PCSK5, ATP6AP2 |
153 | GO:0031290 | 0.00 | 16.80 | 5.43 | 12 | 13 | retinal ganglion cell axon guidance | EFNA5, EPHA7, EPHB1, EPHB3, ISL1, NRCAM, PTPRM, RPL24, SLIT1, VEGFA, SLIT2, SEMA4F |
154 | GO:0090281 | 0.00 | 16.80 | 5.43 | 12 | 13 | negative regulation of calcium ion import | CALM3, CASQ2, GSTM2, NTSR1, PAWR, PLN, SEMG1, SLN, SPINK1, SLC30A1, GSTO1, TRDN |
155 | GO:0001658 | 0.00 | 15.47 | 10.00 | 22 | 24 | branching involved in ureteric bud morphogenesis | BCL2, BMP4, CD44, DLG1, EYA1, FGF1, FGF8, FOXD1, GPC3, HOXD11, ILK, LAMA5, TACSTD2, CITED1, PBX1, PGF, PSPN, PTCH1, SHH, WNT1, DCHS1, SIX2 |
156 | GO:0002076 | 0.00 | 15.40 | 5.01 | 11 | 12 | osteoblast development | ACHE, BGLAP, RUNX2, ESR1, JUND, SMAD3, MEN1, PTHLH, PTH1R, SHH, HDAC4 |
157 | GO:0008045 | 0.00 | 15.40 | 5.01 | 11 | 12 | motor neuron axon guidance | CDK5, CHN1, EGR2, EPHA4, ERBB2, ETV4, FGF8, SEMA3F, SLIT1, SLIT2, SEMA3A |
158 | GO:0030194 | 0.00 | 15.40 | 5.01 | 11 | 12 | positive regulation of blood coagulation | APOH, CD36, F2R, F3, F7, F12, HRG, SERPINE1, S100A9, SELP, USF1 |
159 | GO:0032355 | 0.00 | 14.93 | 28.75 | 63 | 69 | response to estradiol | ADCYAP1R1, AHR, ANXA1, AREG, ASS1, BAD, CCND1, BID, BMP4, BRCA1, BRCA2, C3, CASP8, CASP9, CAT, CCNE1, CD4, CD38, COL1A1, CRYAB, CTGF, CYP1A2, DNMT1, DNMT3A, DNMT3B, DUSP1, EEF2, ETS1, F3, FGA, GJB2, GRN, HIF1A, HMBS, IGF2, IGFBP2, IHH, IL1B, KCNJ11, NRF1, NTS, OGG1, OXT, PAM, PENK, PTCH1, PTN, RARA, RBBP8, SLC6A4, SLC34A1, STAT3, STAT5B, AURKA, TACR3, NR2F2, UCN, PRDM2, ALDH1A2, MBD4, SOCS3, RAMP2, TXNIP |
160 | GO:0044344 | 0.00 | 14.33 | 4.53 | 10 | 11 | cellular response to fibroblast growth factor stimulus | CD44, CDC5L, COL1A1, CPS1, EGR3, SNAI2, SNCA, STAR, ITGB1BP1, CXCL13 |
161 | GO:0002227 | 0.00 | 14.00 | 4.59 | 10 | 11 | innate immune response in mucosa | APOA4, DEFA1, FAU, LTF, RNASE3, RPL39, HIST1H2BG, HIST1H2BF, HIST2H2BE, HIST1H2BJ |
162 | GO:0010881 | 0.00 | 14.00 | 4.59 | 10 | 11 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion | ATP1A2, CALM3, CASQ2, GSTM2, HRC, PLN, PRKACA, RYR2, SLC8A1, GSTO1 |
163 | GO:0015812 | 0.00 | 14.00 | 4.59 | 10 | 11 | gamma-aminobutyric acid transport | ABAT, CACNA1A, CACNB4, NTSR1, P2RX7, SLC6A11, SLC6A12, SLC6A13, TRH, TRPC4 |
164 | GO:0030949 | 0.00 | 14.00 | 4.59 | 10 | 11 | positive regulation of vascular endothelial growth factor receptor signaling pathway | ARNT, FGF9, FLT1, HIF1A, IL1B, ITGA5, PRKCB, VEGFA, VEGFB, VTN |
165 | GO:0060055 | 0.00 | 14.00 | 4.59 | 10 | 11 | angiogenesis involved in wound healing | ETS1, B4GALT1, GPX1, SERPINE1, PIK3CB, PRCP, CX3CL1, SRF, TNFAIP3, VEGFB |
166 | GO:0060307 | 0.00 | 14.00 | 4.59 | 10 | 11 | regulation of ventricular cardiac muscle cell membrane repolarization | CAV3, GJA5, KCNE1, KCNQ1, SCN4B, SCN5A, SNTA1, WDR1, KCNE2, AKAP9 |
167 | GO:0006335 | 0.00 | 13.33 | 8.76 | 19 | 21 | DNA replication-dependent nucleosome assembly | RBBP4, CHAF1B, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HAT1, HIST1H3F |
168 | GO:0007190 | 0.00 | 13.33 | 8.76 | 19 | 21 | activation of adenylate cyclase activity | ADCYAP1R1, ADORA2A, ADRB2, AVPR2, CALM3, EDNRA, FSHR, GHRHR, GLP1R, GNAL, GNAS, NTRK1, NTRK2, P2RY11, PRKCA, RAF1, VIPR2, CAP2, CAP1 |
169 | GO:1903426 | 0.00 | 12.65 | 4.16 | 9 | 10 | regulation of reactive oxygen species biosynthetic process | ACP5, TSPO, IGF1, IL10, PTGIS, SNCA, STAT3, RGN, TRAP1 |
170 | GO:0043500 | 0.00 | 12.65 | 8.34 | 18 | 20 | muscle adaptation | ADK, CAV3, CDK9, CYBA, IGF1, IL1B, P2RX4, PRKCA, RGS2, SLC9A1, TBCE, COL14A1, AKAP1, PDE5A, CTDP1, KLF4, AKAP6, AKAP13 |
171 | GO:0032094 | 0.00 | 12.62 | 4.17 | 9 | 10 | response to food | CLPS, CPS1, GAST, G6PC, GHRH, SLC16A1, SREBF1, BCL10, SOCS3 |
172 | GO:0014821 | 0.00 | 12.59 | 4.17 | 9 | 10 | phasic smooth muscle contraction | DLG1, EDN2, EDN3, EDNRB, GDNF, P2RX3, PTGER4, SSTR2, TACR2 |
173 | GO:0030049 | 0.00 | 12.59 | 4.17 | 9 | 10 | muscle filament sliding | TMOD1, TNNC2, TNNC1, TNNI2, TNNI3, TNNT1, TNNT2, TPM2, VIM |
174 | GO:0035988 | 0.00 | 12.59 | 4.17 | 9 | 10 | chondrocyte proliferation | BMPR2, CTGF, FGFR3, GRN, IHH, LTF, DDR2, STC1, SIX2 |
175 | GO:0043568 | 0.00 | 12.59 | 4.17 | 9 | 10 | positive regulation of insulin-like growth factor receptor signaling pathway | CDH3, GHRH, GHRHR, GHSR, IGF1, IGFBP3, IGFBP5, WNT1, IFT88 |
176 | GO:0071872 | 0.00 | 12.59 | 4.17 | 9 | 10 | cellular response to epinephrine stimulus | KCNQ1, PDE4B, PDE4D, PRKACA, RYR2, SLC9A1, SNCA, SRD5A1, STAR |
177 | GO:0071941 | 0.00 | 12.59 | 4.17 | 9 | 10 | nitrogen cycle metabolic process | ARG1, ARG2, ASL, ASS1, CPS1, OTC, SUOX, NR1H4, SLC25A15 |
178 | GO:0090136 | 0.00 | 12.59 | 4.17 | 9 | 10 | epithelial cell-cell adhesion | CDC42, CTNNA1, IHH, ITGB5, JUP, KIT, SRF, VCL, BVES |
179 | GO:0032570 | 0.00 | 11.92 | 7.93 | 17 | 19 | response to progesterone | ADRB2, BAD, TSPO, C3, CCNE1, CD38, GJB2, JUNB, OXT, PTGER4, PTN, SREBF1, TYMS, FOSL1, SOCS3, RAMP2, TXNIP |
180 | GO:0043434 | 0.00 | 11.73 | 10.99 | 24 | 27 | response to peptide hormone | ANXA1, AREG, STS, BSG, BTG1, CDO1, COL1A1, CTGF, EIF2B1, GIP, GNAI1, JUNB, JUND, LTA4H, OXT, QDPR, SLC2A2, SPARC, TRPV1, EIF2B4, EIF2B3, EIF2B2, EIF2B5, RNF40 |
181 | GO:2000241 | 0.01 | 11.28 | 3.74 | 8 | 9 | regulation of reproductive process | CDC20, CNR1, ESR1, GDF9, B4GALT1, GPR3, RXRA, SPINK1 |
182 | GO:0002444 | 0.01 | 11.23 | 3.75 | 8 | 9 | myeloid leukocyte mediated immunity | KIT, SERPINB9, PIK3CG, S100A13, LAT2, SNAP23, SPON2, CPLX2 |
183 | GO:0014910 | 0.01 | 11.22 | 3.75 | 8 | 9 | regulation of smooth muscle cell migration | ACE, IGFBP3, IGFBP5, ILK, SERPINE1, SORL1, SLIT2, TRIB1 |
184 | GO:0048333 | 0.00 | 11.21 | 7.51 | 16 | 18 | mesodermal cell differentiation | BMP4, BMPR1A, ETV2, EYA1, EYA2, ITGA2, ITGA3, ITGB1, ITGB4, SMAD1, PAX2, TAL1, KDM6A, ITGA8, KLF4, SIX2 |
185 | GO:0060306 | 0.00 | 11.21 | 7.51 | 16 | 18 | regulation of membrane repolarization | CASQ2, CAV3, GJA5, KCNA5, KCNE1, KCNJ2, KCNQ1, SCN4B, SCN5A, SNTA1, AKAP7, AKAP6, WDR1, KCNE2, KCNE3, AKAP9 |
186 | GO:0001702 | 0.01 | 11.21 | 3.75 | 8 | 9 | gastrulation with mouth forming second | ACVR1, ACVR2A, ACVR2B, GATA4, RNF2, UGDH, ZBTB17, CHRD |
187 | GO:0030449 | 0.01 | 11.21 | 3.75 | 8 | 9 | regulation of complement activation | C1QBP, C3, C5, C8B, CFP, PHB, PROS1, VTN |
188 | GO:0019835 | 0.01 | 11.20 | 3.75 | 8 | 9 | cytolysis | ALB, C5, C8B, GPLD1, GZMH, HPRT1, P2RX7, RRAGA |
189 | GO:0003171 | 0.01 | 11.19 | 3.76 | 8 | 9 | atrioventricular valve development | ACVR1, EFNA1, GATA4, GJA5, SOX4, TWIST1, DCHS1, OLFM1 |
190 | GO:0003298 | 0.01 | 11.19 | 3.76 | 8 | 9 | physiological muscle hypertrophy | AGTR2, CAV3, GATA4, COL14A1, SORBS2, CTDP1, AKAP6, PDLIM5 |
191 | GO:0010613 | 0.01 | 11.19 | 3.76 | 8 | 9 | positive regulation of cardiac muscle hypertrophy | ADK, CDK9, IGF1, PRKCA, SLC9A1, TRPC3, PDE5A, AKAP6 |
192 | GO:0023019 | 0.01 | 11.19 | 3.76 | 8 | 9 | signal transduction involved in regulation of gene expression | FGF8, GATA4, FOXA2, EPCAM, SMAD3, P2RY1, T, CER1 |
193 | GO:0030207 | 0.01 | 11.19 | 3.76 | 8 | 9 | chondroitin sulfate catabolic process | VCAN, CSPG4, DCN, HEXA, HEXB, IDS, IDUA, CSPG5 |
194 | GO:0032095 | 0.01 | 11.19 | 3.76 | 8 | 9 | regulation of response to food | BBS2, BBS4, CCK, GCG, GHSR, PRKCG, UCN, CARTPT |
195 | GO:0035994 | 0.01 | 11.19 | 3.76 | 8 | 9 | response to muscle stretch | CAV3, CHUK, JUN, RAF1, RYR2, SLC8A1, SLC9A1, CSRP3 |
196 | GO:0042053 | 0.01 | 11.19 | 3.76 | 8 | 9 | regulation of dopamine metabolic process | ABAT, CHRNB2, COMT, HPRT1, PARK2, PDE1B, SNCA, TACR3 |
197 | GO:0042423 | 0.01 | 11.19 | 3.76 | 8 | 9 | catecholamine biosynthetic process | AGTR2, DAO, DBH, DDC, GATA3, PAH, SNCA, HAND2 |
198 | GO:0042511 | 0.01 | 11.19 | 3.76 | 8 | 9 | positive regulation of tyrosine phosphorylation of Stat1 protein | CD40, FGFR3, HPX, IFNG, KIT, TNFRSF1A, TNFRSF18, TNFSF18 |
199 | GO:0043496 | 0.01 | 11.19 | 3.76 | 8 | 9 | regulation of protein homodimerization activity | BAX, BCL2, NRG1, ISL1, ITGA4, TRAF2, TNFSF18, TRAF4 |
200 | GO:0045540 | 0.01 | 11.19 | 3.76 | 8 | 9 | regulation of cholesterol biosynthetic process | DHCR7, FGF1, PRKAA1, SOD1, SREBF1, ABCG1, ERLIN1, ERLIN2 |
201 | GO:0045603 | 0.01 | 11.19 | 3.76 | 8 | 9 | positive regulation of endothelial cell differentiation | ACVRL1, ALOX12, BMP4, BMP6, BTG1, ETV2, PROC, S1PR2 |
202 | GO:0051580 | 0.01 | 11.19 | 3.76 | 8 | 9 | regulation of neurotransmitter uptake | ATP1A2, GDNF, GFAP, GPM6B, PARK2, RAB3B, SLC18A1, SNCA |
203 | GO:0060037 | 0.01 | 11.19 | 3.76 | 8 | 9 | pharyngeal system development | ACVR1, EYA1, FGF8, GATA3, HES1, ISL1, PTCH1, SIX1 |
204 | GO:0060749 | 0.01 | 11.19 | 3.76 | 8 | 9 | mammary gland alveolus development | AREG, CCND1, CHUK, ESR1, HIF1A, VEGFA, TNFSF11, PHB2 |
205 | GO:0061049 | 0.01 | 11.19 | 3.76 | 8 | 9 | cell growth involved in cardiac muscle cell development | AGTR2, CAV3, GATA4, COL14A1, SORBS2, CTDP1, AKAP6, PDLIM5 |
206 | GO:0097284 | 0.01 | 11.19 | 3.76 | 8 | 9 | hepatocyte apoptotic process | ARF6, BCL2L1, BID, CASP8, DNMT3A, KRT18, PIK3CG, RB1 |
207 | GO:2000136 | 0.01 | 11.19 | 3.76 | 8 | 9 | regulation of cell proliferation involved in heart morphogenesis | BMP4, EYA1, HES1, RBPJ, ISL1, SIX1, SOX9, HAND2 |
208 | GO:0072376 | 0.00 | 10.81 | 10.83 | 23 | 26 | protein activation cascade | C1QA, C1QB, C1QC, C1S, C3, C5, C8B, CD59, CLU, CR1, CR2, CD55, FCN1, FCN2, CFHR1, KRT1, CD46, CFP, PHB, PROS1, VTN, FCN3, VSIG4 |
209 | GO:0071385 | 0.00 | 10.54 | 7.08 | 15 | 17 | cellular response to glucocorticoid stimulus | ACVR1, AHR, ANXA1, ATP2B1, KLF9, FLT3, HMGCS2, ISL1, REST, SGK1, SSTR2, SSTR3, STC1, UBE2L3, AKAP13 |
210 | GO:0060337 | 0.00 | 10.54 | 7.08 | 15 | 17 | type I interferon signaling pathway | BST2, IFI6, IFIT1, IFIT3, IRF1, IRF2, IRF5, ISG20, OAS1, OAS2, OAS3, SP100, OASL, IFITM3, IFITM2 |
211 | GO:0033574 | 0.00 | 10.51 | 7.09 | 15 | 17 | response to testosterone | ADRB2, AVP, BAD, BGLAP, BMP4, TSPO, CDK4, DNMT1, DUSP1, ELK1, HMGCS2, KCNJ11, PLN, PSPH, SRD5A1 |
212 | GO:0048016 | 0.00 | 10.51 | 7.09 | 15 | 17 | inositol phosphate-mediated signaling | RCAN1, EDN2, EDN3, NRG1, HRH1, IGF1, ITPR1, ITPR2, ITPR3, PPP3R1, SLC9A1, SLC12A1, AKAP6, RCAN2, RCAN3 |
213 | GO:1900026 | 0.00 | 10.51 | 7.09 | 15 | 17 | positive regulation of substrate adhesion-dependent cell spreading | APOA1, C1QBP, CDC42, DNM2, FGA, FGG, FLNA, HAS2, RAC1, RAC3, RREB1, S100A10, ARHGEF7, ARPC2, OLFM4 |
214 | GO:0051349 | 0.00 | 10.31 | 10.42 | 22 | 25 | positive regulation of lyase activity | ADCYAP1R1, ADORA2A, ADRB2, AVPR2, CALCR, CALM3, EDNRA, FSHR, GHRHR, GLP1R, GNAL, GNAS, NTRK1, NTRK2, P2RY11, PRKCA, RAF1, VIP, VIPR2, WFS1, CAP2, CAP1 |
215 | GO:0060047 | 0.01 | 10.01 | 3.30 | 7 | 8 | heart contraction | CDC42, ACE, GPX1, RPS6KA2, SGCD, SOD1, ATG5 |
216 | GO:0046394 | 0.01 | 9.95 | 3.31 | 7 | 8 | carboxylic acid biosynthetic process | UGDH, UGP2, UROS, SUCLA2, KYNU, GSTO1, AKR1A1 |
217 | GO:0050880 | 0.01 | 9.93 | 3.31 | 7 | 8 | regulation of blood vessel size | ACTA2, EDNRA, NTS, PIK3C2A, SLC6A4, SLC8A1, ITGB1BP1 |
218 | GO:0042129 | 0.01 | 9.88 | 3.32 | 7 | 8 | regulation of T cell proliferation | CLC, IRF1, LMO1, RAC2, SOS1, SOS2, TNFSF18 |
219 | GO:0071773 | 0.01 | 9.84 | 3.33 | 7 | 8 | cellular response to BMP stimulus | COL2A1, GATA3, KCND3, SPINT1, PHOX2B, SPINT2, ADAMTS7 |
220 | GO:0002705 | 0.01 | 9.83 | 3.33 | 7 | 8 | positive regulation of leukocyte mediated immunity | F2RL1, FGR, IL13, PTAFR, SYK, VAMP8, GAB2 |
221 | GO:0009712 | 0.00 | 9.82 | 10.02 | 21 | 24 | catechol-containing compound metabolic process | ABAT, AGTR2, AOC2, CHRNB2, COMT, DAO, DBH, DDC, GATA3, GRIN2A, HPRT1, PAH, PARK2, PDE1B, SNCB, SNCA, SULT1A1, SULT1A3, TACR3, HAND2, SNCAIP |
222 | GO:0033683 | 0.00 | 9.82 | 10.02 | 21 | 24 | nucleotide-excision repair, DNA incision | DDB1, DDB2, ERCC1, ERCC3, ERCC4, ERCC5, NTHL1, OGG1, RFC1, RFC2, RFC3, RFC4, RFC5, RPA3, RPS27A, UBB, XPA, CUL4B, CUL4A, CHD1L, RBX1 |
223 | GO:0050999 | 0.01 | 9.81 | 3.33 | 7 | 8 | regulation of nitric-oxide synthase activity | ACVR2A, CAV3, CNR1, CNR2, DNM2, HSP90AA1, IL1B |
224 | GO:0042417 | 0.01 | 9.81 | 3.33 | 7 | 8 | dopamine metabolic process | AGTR2, DAO, DBH, DDC, GRIN2A, SNCB, SNCAIP |
225 | GO:0006958 | 0.00 | 9.81 | 6.68 | 14 | 16 | complement activation, classical pathway | C1QBP, SERPING1, C1QA, C1QB, C1QC, C1S, C3, C5, C8B, CLU, CR1, CR2, CD55, CD46 |
226 | GO:0086004 | 0.00 | 9.81 | 6.68 | 14 | 16 | regulation of cardiac muscle cell contraction | ATP1A2, DSC2, DSP, GATA4, GJA5, JUP, KCNJ2, PDE4B, PDE4D, PLN, RYR2, SCN5A, STC1, SUMO1 |
227 | GO:0086091 | 0.00 | 9.81 | 6.68 | 14 | 16 | regulation of heart rate by cardiac conduction | DSC2, DSP, GJA5, JUP, KCNA5, KCNE1, KCNJ2, KCNQ1, SCN2B, SCN4B, SCN5A, KCNE2, HCN4, AKAP9 |
228 | GO:0042730 | 0.01 | 9.81 | 3.34 | 7 | 8 | fibrinolysis | ANXA2, SERPING1, FGA, FGG, GP1BA, KRT1, PROS1 |
229 | GO:0055119 | 0.01 | 9.80 | 3.34 | 7 | 8 | relaxation of cardiac muscle | ATP1A2, GSTM2, KCNJ2, P2RX4, RGS2, SLC8A1, PDE5A |
230 | GO:0010259 | 0.01 | 9.80 | 3.34 | 7 | 8 | multicellular organism aging | CTSV, DDC, ERCC1, NR5A1, WRN, TP63, SEC63 |
231 | GO:0000050 | 0.01 | 9.79 | 3.34 | 7 | 8 | urea cycle | ARG1, ARG2, ASL, ASS1, CPS1, OTC, SLC25A15 |
232 | GO:0001774 | 0.01 | 9.79 | 3.34 | 7 | 8 | microglial cell activation | CLU, CX3CR1, IL13, JUN, CX3CL1, SNCA, TRPV1 |
233 | GO:0002003 | 0.01 | 9.79 | 3.34 | 7 | 8 | angiotensin maturation | ANPEP, CPA3, CTSG, CTSZ, ACE, ENPEP, ATP6AP2 |
234 | GO:0003093 | 0.01 | 9.79 | 3.34 | 7 | 8 | regulation of glomerular filtration | ADORA1, CYBA, EMP2, F2R, F2RL1, GAS6, GJA5 |
235 | GO:0003188 | 0.01 | 9.79 | 3.34 | 7 | 8 | heart valve formation | EFNA1, ERG, GJA5, SOX9, TWIST1, DCHS1, OLFM1 |
236 | GO:0003417 | 0.01 | 9.79 | 3.34 | 7 | 8 | growth plate cartilage development | COL9A1, COMP, RARA, RARB, STC1, CER1, CARM1 |
237 | GO:0007494 | 0.01 | 9.79 | 3.34 | 7 | 8 | midgut development | ASS1, CPS1, EDNRB, HMGCS2, OTC, RXRA, ALDH1A2 |
238 | GO:0009071 | 0.01 | 9.79 | 3.34 | 7 | 8 | serine family amino acid catabolic process | AGXT, AMT, CBS, CDO1, DAO, SHMT1, SDS |
239 | GO:0010224 | 0.01 | 9.79 | 3.34 | 7 | 8 | response to UV-B | BCL2, CDKN1A, ERCC6, HMGN1, IVL, STK11, XPC |
240 | GO:0010523 | 0.01 | 9.79 | 3.34 | 7 | 8 | negative regulation of calcium ion transport into cytosol | BCL2, CALM3, CASQ2, GSTM2, NTSR1, GSTO1, TRDN |
241 | GO:0010669 | 0.01 | 9.79 | 3.34 | 7 | 8 | epithelial structure maintenance | SERPINA3, CXADR, SLC22A5, SOX9, SRF, CROCC, STRAP |
242 | GO:0021794 | 0.01 | 9.79 | 3.34 | 7 | 8 | thalamus development | CHRNB2, OGDH, PTN, SHH, SLC6A4, SRD5A1, OLIG2 |
243 | GO:0030238 | 0.01 | 9.79 | 3.34 | 7 | 8 | male sex determination | NR0B1, FGF9, IGF1R, INSRR, PTGDR, SOX9, SRY |
244 | GO:0032025 | 0.01 | 9.79 | 3.34 | 7 | 8 | response to cobalt ion | ALAD, BNIP3, CASP8, CASP9, HIF1A, HMBS, SERPINF1 |
245 | GO:0033005 | 0.01 | 9.79 | 3.34 | 7 | 8 | positive regulation of mast cell activation | FCER1A, FCER1G, FGR, IL13, SYK, VAMP8, GAB2 |
246 | GO:0033083 | 0.01 | 9.79 | 3.34 | 7 | 8 | regulation of immature T cell proliferation | BMP4, CDKN2A, ERBB2, IHH, IL1B, SHH, RIPK2 |
247 | GO:0042474 | 0.01 | 9.79 | 3.34 | 7 | 8 | middle ear morphogenesis | EYA1, INSIG1, PRRX1, RPL38, SIX1, PRKRA, SIX2 |
248 | GO:0042832 | 0.01 | 9.79 | 3.34 | 7 | 8 | defense response to protozoan | BCL3, CD37, CD40, IFNG, IL10, SLC11A1, BATF |
249 | GO:0045059 | 0.01 | 9.79 | 3.34 | 7 | 8 | positive thymic T cell selection | CD3D, CD74, ITPKB, SHH, SRF, STK11, FOXN1 |
250 | GO:0045188 | 0.01 | 9.79 | 3.34 | 7 | 8 | regulation of circadian sleep/wake cycle, non-REM sleep | ADA, ADORA1, ALB, CHRNB2, GHRHR, KCNA2, PTGER4 |
251 | GO:0045723 | 0.01 | 9.79 | 3.34 | 7 | 8 | positive regulation of fatty acid biosynthetic process | ANXA1, APOA1, APOA4, APOC2, AVP, NR1H2, RGN |
252 | GO:0045821 | 0.01 | 9.79 | 3.34 | 7 | 8 | positive regulation of glycolytic process | ARNT, GPD1, HIF1A, IGF1, INS, P2RX7, PRKAA1 |
253 | GO:0046541 | 0.01 | 9.79 | 3.34 | 7 | 8 | saliva secretion | AQP1, AQP5, CHRM1, CHRM3, KCNN4, TAC1, TRPC1 |
254 | GO:0046689 | 0.01 | 9.79 | 3.34 | 7 | 8 | response to mercury ion | ALAD, ALB, AQP1, BSG, PGAM2, SLC34A1, TAT |
255 | GO:0046716 | 0.01 | 9.79 | 3.34 | 7 | 8 | muscle cell cellular homeostasis | APC, CAV3, CFL2, GAA, HIF1A, SOD1, SRF |
256 | GO:0051194 | 0.01 | 9.79 | 3.34 | 7 | 8 | positive regulation of cofactor metabolic process | ARNT, GPD1, HIF1A, IGF1, INS, P2RX7, PRKAA1 |
257 | GO:0051284 | 0.01 | 9.79 | 3.34 | 7 | 8 | positive regulation of sequestering of calcium ion | CALM3, CASQ2, GSTM2, NTSR1, RYR2, GSTO1, TRDN |
258 | GO:0051482 | 0.01 | 9.79 | 3.34 | 7 | 8 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | S1PR1, LPAR1, EDNRA, F2R, GRM1, HTR2C, KISS1 |
259 | GO:0051917 | 0.01 | 9.79 | 3.34 | 7 | 8 | regulation of fibrinolysis | APOH, F12, FAP, HRG, KLKB1, SERPINE1, USF1 |
260 | GO:0055012 | 0.01 | 9.79 | 3.34 | 7 | 8 | ventricular cardiac muscle cell differentiation | CCNB1, NRG1, PROX1, RARA, RARB, RXRA, ATG5 |
261 | GO:0060056 | 0.01 | 9.79 | 3.34 | 7 | 8 | mammary gland involution | ARG1, BAX, CAPN1, ELF3, B4GALT1, IGFBP5, VDR |
262 | GO:0060177 | 0.01 | 9.79 | 3.34 | 7 | 8 | regulation of angiotensin metabolic process | ANPEP, CPA3, CTSG, CTSZ, ACE, ENPEP, ATP6AP2 |
263 | GO:0060433 | 0.01 | 9.79 | 3.34 | 7 | 8 | bronchus development | BMP4, IL13, SOX9, SRF, TULP3, ADAMTSL2, AGR2 |
264 | GO:0060732 | 0.01 | 9.79 | 3.34 | 7 | 8 | positive regulation of inositol phosphate biosynthetic process | ADCYAP1R1, HRH1, NTSR1, P2RY1, PTAFR, PTH1R, SNCA |
265 | GO:0061437 | 0.01 | 9.79 | 3.34 | 7 | 8 | renal system vasculature development | ACTA2, ANGPT1, ANGPT2, AQP1, BMP4, HES1, SERPINB7 |
266 | GO:0070365 | 0.01 | 9.79 | 3.34 | 7 | 8 | hepatocyte differentiation | ANXA1, BMP4, CPS1, HHEX, ITGA2, PROX1, WNT1 |
267 | GO:0071157 | 0.01 | 9.79 | 3.34 | 7 | 8 | negative regulation of cell cycle arrest | CCND1, CDK4, CDK9, SETMAR, PHOX2B, RASSF1, CHEK2 |
268 | GO:0071361 | 0.01 | 9.79 | 3.34 | 7 | 8 | cellular response to ethanol | ADCY7, DNMT3A, GLRA1, GLRA2, ITPR2, PRKAA1, PRKCE |
269 | GO:0072178 | 0.01 | 9.79 | 3.34 | 7 | 8 | nephric duct morphogenesis | BMP4, EFNB2, EPHA4, EPHA7, GATA3, GPC3, PAX2 |
270 | GO:0086069 | 0.01 | 9.79 | 3.34 | 7 | 8 | bundle of His cell to Purkinje myocyte communication | DSC2, DSP, GJA5, JUP, KCNA5, SCN5A, SCN10A |
271 | GO:0090201 | 0.01 | 9.79 | 3.34 | 7 | 8 | negative regulation of release of cytochrome c from mitochondria | AVP, BCL2L1, GPX1, HGF, IGF1, OPA1, PARK2 |
272 | GO:2000811 | 0.01 | 9.79 | 3.34 | 7 | 8 | negative regulation of anoikis | BCL2, BCL2L1, ITGA5, ITGB1, NTRK2, PDK4, SNAI2 |
273 | GO:0002576 | 0.00 | 9.63 | 19.61 | 41 | 47 | platelet degranulation | A2M, ACTN4, ACTN1, ALB, APOA1, SERPING1, CALM3, CALU, CD9, CD36, CD63, CLU, FCER1G, FGA, FGG, FLNA, GAS6, HGF, HRG, IGF1, IGF2, KNG1, LAMP2, SERPINE1, PF4, PFN1, SRGN, PROS1, SELP, SOD1, SPARC, STXBP1, SYK, TUBA4A, VCL, VEGFA, VEGFB, VEGFC, WDR1, ABCC4, CAP1 |
274 | GO:0072171 | 0.00 | 9.57 | 16.28 | 34 | 39 | mesonephric tubule morphogenesis | AGTR2, BCL2, BMP4, CD44, DLG1, EYA1, FGF1, FGF8, FOXD1, GATA3, GDNF, GPC3, HOXD11, HES1, ILK, LAMA5, TACSTD2, CITED1, PAX2, PBX1, PGF, PSPN, PTCH1, SALL1, SHH, SIX1, SOX9, VEGFA, WNT1, WNT11, WNT2B, PAX8, DCHS1, SIX2 |
275 | GO:0006937 | 0.00 | 9.47 | 19.11 | 40 | 46 | regulation of muscle contraction | ANXA6, CALM3, CASQ2, CAV3, CTGF, DSC2, DSP, GATA4, GJA5, GSTM2, HRC, JUP, KCNA1, KCNJ2, KCNQ1, SMAD7, PPP1R12B, P2RX4, PDE4B, PDE4D, PLN, PRKACA, PRKCA, RYR2, SCN5A, SCN10A, SLC8A1, SLC8A3, SLC9A1, SSTR2, STC1, TNNC2, TNNC1, TNNI2, TNNT2, SUMO1, UCN, GSTO1, HDAC4, HCN4 |
276 | GO:0003091 | 0.00 | 9.35 | 9.60 | 20 | 23 | renal water homeostasis | ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, AQP1, AVP, AVPR2, GNAS, HAS2, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, WFS1, CYP4F2, RAB11A |
277 | GO:0032922 | 0.00 | 9.35 | 9.60 | 20 | 23 | circadian regulation of gene expression | ADK, AHR, ARNTL, ATF4, CRY1, CRY2, CSNK1D, PER1, PPP1CA, RELB, TOP1, NRIP1, OGT, HDAC3, PER3, USP2, NR1D1, CLOCK, CARTPT, RAI1 |
278 | GO:1902041 | 0.00 | 9.12 | 6.25 | 13 | 15 | regulation of extrinsic apoptotic signaling pathway via death domain receptors | ATF3, CASP8, MAL, SP100, TRAF2, TRPS1, MADD, TRADD, RIPK1, TNFSF10, TNFRSF10B, TNFRSF10A, FEM1B |
279 | GO:1903307 | 0.00 | 9.12 | 6.25 | 13 | 15 | positive regulation of regulated secretory pathway | AP1G1, F2RL1, FCER1A, FCER1G, FGR, IL13, PTAFR, RAB3A, RAB27A, SYK, VAMP8, RAB3D, GAB2 |
280 | GO:0010039 | 0.00 | 9.10 | 6.26 | 13 | 15 | response to iron ion | ABAT, ACO1, ALAD, APBB1, CCND1, BCL2, BMP6, C1QA, CCNB1, CPOX, SLC11A2, PAWR, SNCA |
281 | GO:0034199 | 0.00 | 9.10 | 6.26 | 13 | 15 | activation of protein kinase A activity | ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, UCN |
282 | GO:0042776 | 0.00 | 9.10 | 6.26 | 13 | 15 | mitochondrial ATP synthesis coupled proton transport | ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, ATP5J2, ATP5H, ATP5L |
283 | GO:0043555 | 0.00 | 9.10 | 6.26 | 13 | 15 | regulation of translation in response to stress | ATF4, EIF2S1, FECH, PPP1CA, EIF2AK2, DNAJC3, RBM4, RPS6KA1, RPS6KA3, EIF2B4, EIF2B3, EIF2B5, EIF2AK3 |
284 | GO:0051412 | 0.00 | 9.10 | 6.26 | 13 | 15 | response to corticosterone | ATP2B1, BAX, CCND1, CALM3, CCNE1, CDKN1A, JUNB, NTRK3, NTS, PTGS1, STAR, TRH, FOSL1 |
285 | GO:0038083 | 0.00 | 8.88 | 9.18 | 19 | 22 | peptidyl-tyrosine autophosphorylation | ABL2, BLK, BMX, BTK, ACE, FGR, FRK, FYN, HCK, IGF1R, KDR, MAPK3, SRMS, SYK, TYK2, VEGFA, TNK1, AATK, TNK2 |
286 | GO:0010518 | 0.02 | 8.47 | 2.91 | 6 | 7 | positive regulation of phospholipase activity | APOC2, ARF4, ARL1, FGFR3, PDPK1, PRKCZ |
287 | GO:0031016 | 0.00 | 8.45 | 5.82 | 12 | 14 | pancreas development | ACVR2B, APC, HHEX, IGF1, IGF1R, IGF2, IHH, ISL1, PROX1, SHH, IFT88, ALDH1A2 |
288 | GO:0030858 | 0.00 | 8.44 | 5.83 | 12 | 14 | positive regulation of epithelial cell differentiation | APC, BAD, DMBT1, GDNF, IL13, PAX2, RFX3, SOX2, SOX9, PAX8, NUMB, PROM1 |
289 | GO:0035148 | 0.02 | 8.44 | 2.91 | 6 | 7 | tube formation | EDA, SHH, VEGFA, ITGB1BP1, BCL2L11, EDAR |
290 | GO:0001892 | 0.02 | 8.43 | 2.91 | 6 | 7 | embryonic placenta development | ARNT, CSF2, HIF1A, SLC8A1, SP1, SP3 |
291 | GO:0050764 | 0.02 | 8.43 | 2.91 | 6 | 7 | regulation of phagocytosis | BLK, SCARB1, FGR, HCK, PRKCG, SYK |
292 | GO:0006968 | 0.00 | 8.42 | 11.69 | 24 | 28 | cellular defense response | ADORA2A, CD5L, CCR3, CCR5, CX3CR1, ITGB1, KLRC2, KLRC3, LSP1, SPN, TNFRSF4, TYROBP, ZNF148, VEZF1, FOSL1, KLRC4, BECN1, PAGE1, IL1RL2, BCL10, GNLY, CCR9, CD300C, CD160 |
293 | GO:0043299 | 0.02 | 8.42 | 2.91 | 6 | 7 | leukocyte degranulation | ANXA3, HCK, RAB27A, STXBP3, STX11, CORO1A |
294 | GO:1901616 | 0.02 | 8.42 | 2.92 | 6 | 7 | organic hydroxy compound catabolic process | ACADL, COMT, DBH, DIO3, SULT2A1, CYP4F2 |
295 | GO:0010092 | 0.02 | 8.41 | 2.92 | 6 | 7 | specification of organ identity | RBPJ, ISL1, PAX2, SMARCD3, PAX8, TBR1 |
296 | GO:0002089 | 0.00 | 8.40 | 5.84 | 12 | 14 | lens morphogenesis in camera-type eye | SHROOM2, BMP4, CRYGB, EPHA2, FGFR3, MEIS1, PROX1, SIX3, SOX1, SOX2, SOX11, BCAR3 |
297 | GO:0010575 | 0.00 | 8.40 | 5.84 | 12 | 14 | positive regulation of vascular endothelial growth factor production | ARNT, ATF4, BRCA1, C3, C5, FLT4, GATA4, HIF1A, IL1A, IL1B, ISL1, EIF2AK3 |
298 | GO:0045909 | 0.00 | 8.40 | 5.84 | 12 | 14 | positive regulation of vasodilation | ADRB2, AGTR2, ALOX12, CPS1, F2RL1, GJA5, INS, PTAFR, PTPRM, UCN, VIP, KAT2B |
299 | GO:0065005 | 0.00 | 8.40 | 5.84 | 12 | 14 | protein-lipid complex assembly | ABCA1, BIN1, APOA1, APOA4, ARF1, ACSL3, FECH, LCAT, NR1H2, SOAT2, DGAT1, ABCA7 |
300 | GO:0002320 | 0.02 | 8.40 | 2.92 | 6 | 7 | lymphoid progenitor cell differentiation | BCL2, BMP4, GATA3, KIT, SHH, BATF |
301 | GO:0032228 | 0.02 | 8.40 | 2.92 | 6 | 7 | regulation of synaptic transmission, GABAergic | ADORA1, CNR1, CNR2, KRAS, STXBP1, SYN3 |
302 | GO:0060444 | 0.02 | 8.40 | 2.92 | 6 | 7 | branching involved in mammary gland duct morphogenesis | AREG, EPHA2, ESR1, PGR, SLC12A2, VDR |
303 | GO:0001765 | 0.02 | 8.39 | 2.92 | 6 | 7 | membrane raft assembly | ANXA2, CAV2, CAV3, EMP2, FLOT2, S100A10 |
304 | GO:0002726 | 0.02 | 8.39 | 2.92 | 6 | 7 | positive regulation of T cell cytokine production | PRKCZ, XCL1, TRAF2, TNFSF4, FZD5, MALT1 |
305 | GO:0002864 | 0.02 | 8.39 | 2.92 | 6 | 7 | regulation of acute inflammatory response to antigenic stimulus | C3, CNR1, FCER1A, FCER1G, SPN, ZP3 |
306 | GO:0006105 | 0.02 | 8.39 | 2.92 | 6 | 7 | succinate metabolic process | GAD1, GAD2, SDHB, STAT5B, SUCLG1, SUCLA2 |
307 | GO:0007063 | 0.02 | 8.39 | 2.92 | 6 | 7 | regulation of sister chromatid cohesion | ATRX, BUB1, RB1, SFPQ, TNKS, CTCF |
308 | GO:0007350 | 0.02 | 8.39 | 2.92 | 6 | 7 | blastoderm segmentation | HOXD8, PCSK6, SEMA3F, T, FZD5, SEMA3A |
309 | GO:0007501 | 0.02 | 8.39 | 2.92 | 6 | 7 | mesodermal cell fate specification | BMPR1A, ETV2, EYA1, EYA2, PAX2, SIX2 |
310 | GO:0009820 | 0.02 | 8.39 | 2.92 | 6 | 7 | alkaloid metabolic process | BCHE, CYP1A2, CYP3A4, CYP3A5, DDC, PTGIS |
311 | GO:0010640 | 0.02 | 8.39 | 2.92 | 6 | 7 | regulation of platelet-derived growth factor receptor signaling pathway | F3, F7, PTPRJ, SNCA, SLC9A3R1, PHF14 |
312 | GO:0010649 | 0.02 | 8.39 | 2.92 | 6 | 7 | regulation of cell communication by electrical coupling | CALM3, CASQ2, HRC, PDE4D, SLC8A1, TRDN |
313 | GO:0010745 | 0.02 | 8.39 | 2.92 | 6 | 7 | negative regulation of macrophage derived foam cell differentiation | ABCA1, CETP, CRP, ITGAV, NR1H2, ABCG1 |
314 | GO:0010896 | 0.02 | 8.39 | 2.92 | 6 | 7 | regulation of triglyceride catabolic process | APOA1, APOA4, APOC2, APOH, GPLD1, PIK3CG |
315 | GO:0014819 | 0.02 | 8.39 | 2.92 | 6 | 7 | regulation of skeletal muscle contraction | ATP2A1, CAV3, GSTM2, KCNJ2, SLC8A3, GSTO1 |
316 | GO:0019740 | 0.02 | 8.39 | 2.92 | 6 | 7 | nitrogen utilization | BAX, BCL2, RHAG, RHCE, RHD, NR1H4 |
317 | GO:0019755 | 0.02 | 8.39 | 2.92 | 6 | 7 | one-carbon compound transport | AQP1, AQP5, AQP7, RHAG, UPK3A, SLC14A2 |
318 | GO:0021819 | 0.02 | 8.39 | 2.92 | 6 | 7 | layer formation in cerebral cortex | CDK5, DCX, RELN, NR2E1, LRP8, CDK5R2 |
319 | GO:0030953 | 0.02 | 8.39 | 2.92 | 6 | 7 | astral microtubule organization | DLG1, KPNB1, EZR, RAB11A, TACC3, TACC2 |
320 | GO:0031077 | 0.02 | 8.39 | 2.92 | 6 | 7 | post-embryonic camera-type eye development | BAX, HMGN1, KDR, VEGFA, FZD5, KLF4 |
321 | GO:0032530 | 0.02 | 8.39 | 2.92 | 6 | 7 | regulation of microvillus organization | KLF5, ATP8B1, RAP1GAP, VIL1, EZR, TWF2 |
322 | GO:0032928 | 0.02 | 8.39 | 2.92 | 6 | 7 | regulation of superoxide anion generation | ACP5, CRP, CYBA, F2RL1, SOD1, SYK |
323 | GO:0033131 | 0.02 | 8.39 | 2.92 | 6 | 7 | regulation of glucokinase activity | BAD, FOXA2, PARK2, PFKFB2, RANBP2, DUSP12 |
324 | GO:0033631 | 0.02 | 8.39 | 2.92 | 6 | 7 | cell-cell adhesion mediated by integrin | ADA, DPP4, ITGA5, ITGB1, ADAM9, CXCL13 |
325 | GO:0034380 | 0.02 | 8.39 | 2.92 | 6 | 7 | high-density lipoprotein particle assembly | ABCA1, APOA1, APOA4, LCAT, NR1H2, ABCA7 |
326 | GO:0035815 | 0.02 | 8.39 | 2.92 | 6 | 7 | positive regulation of renal sodium excretion | AGTR2, EDNRB, KNG1, OXT, PTGER4, TAC1 |
327 | GO:0042541 | 0.02 | 8.39 | 2.92 | 6 | 7 | hemoglobin biosynthetic process | ALAS2, FECH, HIF1A, PRMT1, INHA, KLF4 |
328 | GO:0043116 | 0.02 | 8.39 | 2.92 | 6 | 7 | negative regulation of vascular permeability | ANGPT1, ARHGAP35, PDE3A, PTPRJ, SLIT2, RAMP2 |
329 | GO:0045589 | 0.02 | 8.39 | 2.92 | 6 | 7 | regulation of regulatory T cell differentiation | CD28, CTLA4, IFNG, IRF1, CD46, TNFSF4 |
330 | GO:0045916 | 0.02 | 8.39 | 2.92 | 6 | 7 | negative regulation of complement activation | A2M, SERPING1, CD59, CR1, CD55, CD46 |
331 | GO:0048642 | 0.02 | 8.39 | 2.92 | 6 | 7 | negative regulation of skeletal muscle tissue development | TSC22D3, NRAS, S100B, TWIST1, USP2, USP19 |
332 | GO:0050667 | 0.02 | 8.39 | 2.92 | 6 | 7 | homocysteine metabolic process | BHMT, CBS, COMT, CPS1, CTH, DPEP1 |
333 | GO:0051589 | 0.02 | 8.39 | 2.92 | 6 | 7 | negative regulation of neurotransmitter transport | GPM6B, PARK2, RAP1A, SLC18A1, SNCA, SLC30A1 |
334 | GO:0051593 | 0.02 | 8.39 | 2.92 | 6 | 7 | response to folic acid | BCHE, EEF2, MGMT, NRF1, OGG1, TYMS |
335 | GO:0051764 | 0.02 | 8.39 | 2.92 | 6 | 7 | actin crosslink formation | ACTN1, DPYSL3, EPS8, FLNA, TNNT2, BAIAP2 |
336 | GO:0060045 | 0.02 | 8.39 | 2.92 | 6 | 7 | positive regulation of cardiac muscle cell proliferation | CCNB1, GATA4, GATA6, NRG1, RBPJ, WNT2 |
337 | GO:0060080 | 0.02 | 8.39 | 2.92 | 6 | 7 | inhibitory postsynaptic potential | ABAT, GLRA1, NTSR1, CX3CL1, RIMS2, UNC13B |
338 | GO:0060253 | 0.02 | 8.39 | 2.92 | 6 | 7 | negative regulation of glial cell proliferation | ASCL2, TSPO, HES1, PTN, SOX11, RNF10 |
339 | GO:0060379 | 0.02 | 8.39 | 2.92 | 6 | 7 | cardiac muscle cell myoblast differentiation | NRG1, RBPJ, ISL1, REST, SRF, T |
340 | GO:0060850 | 0.02 | 8.39 | 2.92 | 6 | 7 | regulation of transcription involved in cell fate commitment | BMP4, ETV2, EVX1, PROX1, SMARCC2, NR2F2 |
341 | GO:0061081 | 0.02 | 8.39 | 2.92 | 6 | 7 | positive regulation of myeloid leukocyte cytokine production involved in immune response | CD36, CD74, FCER1G, SEMA7A, BCL10, SPON2 |
342 | GO:0070669 | 0.02 | 8.39 | 2.92 | 6 | 7 | response to interleukin-2 | CDC5L, IL2RA, IL2RB, IL2RG, CITED1, STAT5B |
343 | GO:0071550 | 0.02 | 8.39 | 2.92 | 6 | 7 | death-inducing signaling complex assembly | CASP8, RAF1, TNFRSF1A, TRAF2, TRADD, RIPK1 |
344 | GO:0080184 | 0.02 | 8.39 | 2.92 | 6 | 7 | response to phenylpropanoid | APOA4, BGLAP, CAT, CD36, FGA, IL1B |
345 | GO:0097067 | 0.02 | 8.39 | 2.92 | 6 | 7 | cellular response to thyroid hormone stimulus | BMP4, KLF9, CTSS, KIT, RDX, GAS2L1 |
346 | GO:2001014 | 0.02 | 8.39 | 2.92 | 6 | 7 | regulation of skeletal muscle cell differentiation | ARNTL, DDX5, GPC1, S100B, SIX1, NR1D2 |
347 | GO:0009725 | 0.00 | 8.32 | 48.24 | 102 | 121 | response to hormone | ABCA2, ACADS, ACAT1, ADCYAP1R1, ADRB2, AGXT, AK2, ALAD, ALDH3A1, ANG, ANXA2, ANXA3, APOA1, AVP, BAD, BAX, BCHE, BCL2, BGLAP, BID, BMP6, BRCA2, TSPO, C3, CA2, CALCR, CASP8, CBLB, CD4, CD38, CDK4, CDKN1A, CRYAB, CTNNA1, CYP1A2, CYP27B1, DHCR24, DNMT1, DNMT3A, DTYMK, EEF2, ETS1, F3, FGA, GATA3, GRN, H3F3B, HCLS1, HPN, IDH1, IHH, IL1RN, KCNJ11, KRT19, LCAT, LDHA, SMAD6, MFGE8, NRF1, NTRK3, OGG1, TNFRSF11B, OXCT1, PAM, PENK, PSPH, PTAFR, PTCH1, PTGS1, PTN, RBBP8, S100B, SDC1, SFRP4, SLC6A4, SLC9A3, SNRPN, SORD, SRF, AURKA, TAC1, TACR3, TAT, TSHB, TYMS, UCN, SCGB1A1, UQCRFS1, TRIM25, PRDM2, FOSL1, ADAM9, RGS9, ALDH1A2, MBD4, ABCG1, PTPRU, CITED2, PIAS3, SLC34A2, TXNIP, SOX30 |
348 | GO:0050679 | 0.00 | 8.03 | 16.63 | 34 | 40 | positive regulation of epithelial cell proliferation | BAD, CCND1, BMPR1A, CDC42, CDH3, DLX5, DLX6, ERBB2, ESR1, EYA1, FGF1, FGF7, FGF9, B4GALT1, GLUL, GRN, HAS2, HPN, IGF1, IHH, REG3A, PAX2, PTN, RREB1, SCN5A, SRSF6, SHH, SOX9, SOX11, TNFAIP3, TWIST1, VEGFC, FZD7, TP63 |
349 | GO:0001704 | 0.00 | 8.00 | 8.31 | 17 | 20 | formation of primary germ layer | COL5A1, COL5A2, COL11A1, COL12A1, DUSP1, DUSP4, DUSP5, GATA4, FOXA2, HSBP1, ITGA4, ITGA5, ITGA7, ITGAV, ITGB5, LAMA3, VTN |
350 | GO:0007202 | 0.00 | 7.97 | 16.69 | 34 | 40 | activation of phospholipase C activity | ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADCYAP1R1, ADRBK1, ANG, ARHGAP6, AVPR1B, CALM3, CAMK4, LPAR1, EDNRA, GNA15, GNAQ, ITPR1, ITPR2, ITPR3, NTRK1, PDE1B, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCE, PRKCG, SELE, S1PR4, GPR55 |
351 | GO:0043113 | 0.00 | 7.95 | 8.34 | 17 | 20 | receptor clustering | CACNA1A, CDK5, DLG1, DLG2, DLG3, FLNA, GLRB, ITGA4, ITGAL, PIGR, RELN, MADCAM1, SSNA1, ITGB1BP1, NRXN1, NRXN2, PICK1 |
352 | GO:0022400 | 0.00 | 7.94 | 8.35 | 17 | 20 | regulation of rhodopsin mediated signaling pathway | CALM3, CNGA1, FNTA, GNAT1, GNB1, GNGT1, GUCA1A, GUCA1B, GUCY2F, GUCY2D, PDE6G, PRKCA, PRKCQ, RCVRN, SAG, RGS9, GUCA1C |
353 | GO:0050690 | 0.00 | 7.94 | 8.35 | 17 | 20 | regulation of defense response to virus by virus | AP2A1, AP2B1, AP1G1, ARF1, CD4, CD28, AP2M1, AP1S1, AP2S1, FYN, HCK, EIF2AK2, RAC1, AP1S2, AP1M1, ELMO1, AP1M2 |
354 | GO:0051930 | 0.00 | 7.94 | 8.35 | 17 | 20 | regulation of sensory perception of pain | ADORA1, ADRA2C, ADRB2, CCK, COMT, EDNRB, F2R, GRIN2A, GRM1, IL10, NTSR1, OXT, P2RX3, PTAFR, SLC9A1, VIP, SCN11A |
355 | GO:2001240 | 0.00 | 7.94 | 8.35 | 17 | 20 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | BCL2, BCL2L1, COL2A1, CSF2, CTNNA1, CX3CR1, EYA1, FYN, IFI6, GDNF, NRG1, IL1A, IL1B, PF4, CX3CL1, SNAI2, RIPK1 |
356 | GO:0048146 | 0.00 | 7.72 | 10.85 | 22 | 26 | positive regulation of fibroblast proliferation | ANXA2, AQP1, BMI1, CCNB1, CD74, CDC6, CDK4, CDK6, CDKN1A, EREG, ESR1, FBLN1, GAS6, IGF1, IL13, JUN, NRAS, DDR2, PTPRZ1, S100A6, WNT1, WNT2 |
357 | GO:0048661 | 0.00 | 7.72 | 10.85 | 22 | 26 | positive regulation of smooth muscle cell proliferation | ALOX12, BMP4, CYBA, HBEGF, S1PR1, EREG, FLT1, HIF1A, HMGCR, IGF1, IL13, IRAK1, ITGA2, JUN, ORC1, PTAFR, CX3CL1, SHC1, SKP2, STAT5B, HDAC4, CALCRL |
358 | GO:1903792 | 0.00 | 7.71 | 5.42 | 11 | 13 | negative regulation of anion transport | ABAT, ADORA1, CNR1, GPM6B, GRK6, IL1B, SFRP4, SLC18A1, SNCA, TRH, HRH3 |
359 | GO:0001829 | 0.00 | 7.70 | 5.43 | 11 | 13 | trophectodermal cell differentiation | ADA, BYSL, CDX2, JUNB, CNOT2, SP1, SP3, SRF, EOMES, CUL3, HAND1 |
360 | GO:0002068 | 0.00 | 7.70 | 5.43 | 11 | 13 | glandular epithelial cell development | ARNTL, BAD, BMP4, BMP6, CDK6, PDPK1, RARA, RARB, RFX3, RHEB, CLOCK |
361 | GO:0003309 | 0.00 | 7.70 | 5.43 | 11 | 13 | type B pancreatic cell differentiation | ARNTL, BAD, BMP4, BMP6, CDK6, GATA6, MEN1, PDPK1, RFX3, RHEB, CLOCK |
362 | GO:0006198 | 0.00 | 7.70 | 5.43 | 11 | 13 | cAMP catabolic process | PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, RAPGEF3, PDE10A |
363 | GO:0007431 | 0.00 | 7.70 | 5.43 | 11 | 13 | salivary gland development | CDC42, CLCN2, EDA, FGF7, FGF8, HGF, LAMA5, SHH, SNAI2, SEMA3A, EDAR |
364 | GO:0007597 | 0.00 | 7.70 | 5.43 | 11 | 13 | blood coagulation, intrinsic pathway | A2M, APOH, SERPINC1, C1QBP, SERPING1, F10, F12, GP1BA, KLKB1, KNG1, PRCP |
365 | GO:0030878 | 0.00 | 7.70 | 5.43 | 11 | 13 | thyroid gland development | FGF8, HHEX, HOXD3, SMAD3, MAPK3, RAF1, RAP1GAP, SHH, SIX1, SRF, PAX8 |
366 | GO:0048745 | 0.00 | 7.70 | 5.43 | 11 | 13 | smooth muscle tissue development | BMP4, COL3A1, DLG1, IHH, PROX1, SHH, SIX1, SOX9, SRF, ITGA8, TP63 |
367 | GO:0090023 | 0.00 | 7.70 | 5.43 | 11 | 13 | positive regulation of neutrophil chemotaxis | C1QBP, CD74, EDNRA, CXCL1, CXCL2, CXCL3, IL1B, RAC1, RAC2, CCL21, XCL1 |
368 | GO:0009889 | 0.04 | 7.69 | 2.37 | 5 | 6 | regulation of biosynthetic process | ITGAV, PGGT1B, RAP1A, STAR, SEC24A |
369 | GO:0048511 | 0.00 | 7.54 | 10.29 | 21 | 25 | rhythmic process | ADRB2, ANXA1, AXL, CDK5, CLU, CSNK2A1, EGR2, ETS1, HAS1, HAS2, HLF, SERPINF1, PTN, SP1, TRPM2, TWIST1, TYRO3, KDM5C, KAT2B, ENOX2, CBX3 |
370 | GO:0001657 | 0.00 | 7.53 | 23.79 | 48 | 57 | ureteric bud development | AGTR2, ARG2, BCL2, BMP4, CAT, CD44, DLG1, EYA1, FGF1, FGF8, FOXD1, GATA3, GDNF, GPC3, HOXD11, HES1, ILK, LAMA5, TACSTD2, EPCAM, SMAD1, SMAD3, SMAD6, SMAD7, CITED1, PAX2, PBX1, PGF, PSPN, PTCH1, RARA, RARB, SALL1, SDC1, SDC4, SHH, SIX1, SOX9, VEGFA, WNT1, WNT11, WNT2B, PAX8, DCHS1, CRLF1, CER1, SLIT2, SIX2 |
371 | GO:0072163 | 0.00 | 7.53 | 23.79 | 48 | 57 | mesonephric epithelium development | AGTR2, ARG2, BCL2, BMP4, CAT, CD44, DLG1, EYA1, FGF1, FGF8, FOXD1, GATA3, GDNF, GPC3, HOXD11, HES1, ILK, LAMA5, TACSTD2, EPCAM, SMAD1, SMAD3, SMAD6, SMAD7, CITED1, PAX2, PBX1, PGF, PSPN, PTCH1, RARA, RARB, SALL1, SDC1, SDC4, SHH, SIX1, SOX9, VEGFA, WNT1, WNT11, WNT2B, PAX8, DCHS1, CRLF1, CER1, SLIT2, SIX2 |
372 | GO:0070098 | 0.00 | 7.50 | 15.86 | 32 | 38 | chemokine-mediated signaling pathway | CCR1, CCR3, CCR5, CCR8, ACKR2, CMKLR1, CX3CR1, ACKR1, CCR10, XCR1, GPR17, CXCL1, CXCL2, CXCL3, HIF1A, PF4, PF4V1, CCL20, CCL21, CCL22, CCL24, CCL25, CXCL6, CXCL5, XCL1, CX3CL1, SLIT3, XCL2, SLIT2, CXCL13, CXCR6, CCR9 |
373 | GO:0010939 | 0.00 | 7.47 | 7.93 | 16 | 19 | regulation of necrotic cell death | SLC25A4, BIRC3, TSPO, CASP8, RPS27A, TRAF2, UBB, UCN, TRADD, RIPK1, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR, ARHGEF2, RBCK1 |
374 | GO:0034694 | 0.00 | 7.47 | 7.93 | 16 | 19 | response to prostaglandin | ADCY6, GNAS, GNB1, HMGCS2, TNC, OXT, P2RY4, P2RY6, PRKAA1, PRKCE, PTGDR, PTGER4, CCL21, TNFSF4, AKR1C3, ADAMTS1 |
375 | GO:0046189 | 0.00 | 7.47 | 7.93 | 16 | 19 | phenol-containing compound biosynthetic process | AGTR2, ASIP, CDH3, CTNS, DAO, DBH, DDC, GATA3, CITED1, PAH, SNCA, TRPC1, TYRP1, HAND2, RAPGEF2, ZEB2 |
376 | GO:0071320 | 0.00 | 7.26 | 15.44 | 31 | 37 | cellular response to cAMP | AQP1, ASS1, HCN2, CFTR, CPS1, GPD1, RAPGEF1, IGFBP5, ITPR2, ITPR3, KCNE1, KCNQ1, PDE4D, PENK, PIK3CG, PTAFR, RAP1A, SLC5A5, SLC8A1, SLC8A3, SRD5A1, STAR, STC1, EZR, AKAP1, AKAP7, AKAP6, RAPGEF2, HCN4, AKAP9, RAPGEF3 |
377 | GO:0060322 | 0.04 | 7.26 | 2.45 | 5 | 6 | head development | DLX6, EDNRA, IHH, IL11RA, ATP6AP2 |
378 | GO:0007159 | 0.00 | 7.21 | 4.92 | 10 | 12 | leukocyte cell-cell adhesion | APOA4, ITGA5, ITGB1, OLR1, SELE, SELP, SELPLG, EZR, MADCAM1, TNIP1 |
379 | GO:0007229 | 0.00 | 7.20 | 25.46 | 51 | 61 | integrin-mediated signaling pathway | ADAM10, APOA1, DST, CD63, CDH17, COL3A1, COL16A1, CTGF, CTNNA1, EMP2, FCER1G, FGR, FLNA, FUT8, HCK, ILK, ITGA6, ITGA1, ITGA2, ITGA3, ITGA4, ITGA5, ITGA7, ITGA9, ITGAD, ITGAE, ITGAL, ITGAM, ITGAV, ITGAX, ITGB1, ITGB4, ITGB5, LAMA5, PRKD1, SYK, TYROBP, VAV1, MADCAM1, CUL3, SEMA7A, ITGA8, ADAM15, ADAM9, ITGB1BP1, ADAMTS1, BCAR1, GAB2, VAV3, FERMT2, ADAMTS13 |
380 | GO:0052548 | 0.05 | 7.12 | 2.48 | 5 | 6 | regulation of endopeptidase activity | EPHA7, MGMT, SOX2, TP63, KIAA0141 |
381 | GO:0051251 | 0.05 | 7.10 | 2.48 | 5 | 6 | positive regulation of lymphocyte activation | AP1G1, AXL, FLT3LG, GAS6, TAC1 |
382 | GO:0009308 | 0.05 | 7.09 | 2.48 | 5 | 6 | amine metabolic process | AOC2, SULT1A1, SULT1C2, AOC3, INMT |
383 | GO:2000377 | 0.00 | 7.07 | 4.98 | 10 | 12 | regulation of reactive oxygen species metabolic process | ARF4, DHFR, PRCP, RAC1, RAC2, SYK, STK17A, COQ7, FBLN5, TUSC2 |
384 | GO:0034332 | 0.00 | 7.05 | 9.98 | 20 | 24 | adherens junction organization | ACTB, ACTG1, ANG, CDC42, CDH1, CDH3, CDH6, CDH7, CDH8, CDH9, CDH10, CDH12, CDH15, CDH17, CTNNA1, CTNND1, DSP, PVR, NUMB, NUMBL |
385 | GO:0090277 | 0.00 | 7.03 | 4.99 | 10 | 12 | positive regulation of peptide hormone secretion | FGA, FGG, GHRH, GHRHR, INS, KISS1, PTGER4, UCN, TNFSF11, ARHGEF7 |
386 | GO:0050918 | 0.00 | 7.03 | 5.00 | 10 | 12 | positive chemotaxis | ANGPT1, ANGPT2, BMP4, FGF7, FGF8, HGF, PTPRJ, SAA4, TSC2, CORO1A |
387 | GO:0050810 | 0.05 | 7.02 | 2.50 | 5 | 6 | regulation of steroid biosynthetic process | TSPO, NR5A1, STAR, VDR, AKR1C3 |
388 | GO:0042089 | 0.05 | 7.02 | 2.50 | 5 | 6 | cytokine biosynthetic process | CEBPE, IL1RAP, IL18, PAWR, PCSK5 |
389 | GO:0033627 | 0.05 | 7.02 | 2.50 | 5 | 6 | cell adhesion mediated by integrin | COL16A1, ICAM1, ITGA6, ITGA2, VTN |
390 | GO:0090303 | 0.00 | 7.02 | 5.00 | 10 | 12 | positive regulation of wound healing | ANXA1, HBEGF, INSL3, REG3A, PRKCE, PTGER4, RREB1, VEGFB, VTN, ARFGEF1 |
391 | GO:1903428 | 0.05 | 7.01 | 2.50 | 5 | 6 | positive regulation of reactive oxygen species biosynthetic process | CLCN3, CYBA, RAB27A, OGT, HDAC4 |
392 | GO:0046902 | 0.05 | 7.01 | 2.50 | 5 | 6 | regulation of mitochondrial membrane permeability | BCL2L1, CAMK2A, CNP, HK2, STAT3 |
393 | GO:0051290 | 0.00 | 7.01 | 10.02 | 20 | 24 | protein heterotetramerization | ANXA2, RRM1, RRM2, S100A10, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HIST1H3F |
394 | GO:0019048 | 0.05 | 7.01 | 2.50 | 5 | 6 | modulation by virus of host morphology or physiology | FBLN1, SMAD3, RXRA, TYMS, RRAGA |
395 | GO:0071312 | 0.00 | 7.01 | 5.00 | 10 | 12 | cellular response to alkaloid | BAD, BCL2L1, DDC, ICAM1, KCNJ11, NTRK1, RAD51, SLC34A1, STAR, TRPV1 |
396 | GO:0009268 | 0.00 | 7.01 | 5.00 | 10 | 12 | response to pH | STS, CA2, CLCN7, GJA3, GPLD1, INSRR, KCNJ8, PAM, ABCC8, TRPV1 |
397 | GO:0030947 | 0.05 | 7.01 | 2.50 | 5 | 6 | regulation of vascular endothelial growth factor receptor signaling pathway | HHEX, PTPN1, VEGFC, FZD4, PDCD6 |
398 | GO:0014808 | 0.00 | 7.00 | 7.51 | 15 | 18 | release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | ATP1A2, CALM3, CASQ2, CCR5, GSTM2, HRC, PDE4D, PLN, PRKACA, RYR1, RYR2, SLC8A1, GSTO1, AKAP6, TRDN |
399 | GO:0045987 | 0.00 | 7.00 | 7.51 | 15 | 18 | positive regulation of smooth muscle contraction | ABAT, ADA, ADRA1B, CHRM3, EDN2, CTTN, F2R, ITGA2, OXT, PAWR, PTAFR, PTGS1, SRF, TACR2, TACR3 |
400 | GO:0006699 | 0.00 | 7.00 | 5.00 | 10 | 12 | bile acid biosynthetic process | AKR1C4, CYP8B1, HSD17B4, SCP2, STAR, ACOX2, CH25H, ACOT8, SLC27A5, SLC27A2 |
401 | GO:0010288 | 0.00 | 7.00 | 5.00 | 10 | 12 | response to lead ion | CAT, CDK4, CPOX, DNMT3A, FECH, PPP5C, QDPR, SLC34A1, SPARC, STAR |
402 | GO:0098751 | 0.05 | 7.00 | 2.50 | 5 | 6 | bone cell development | ANXA2, ATP6AP1, LTF, TYROBP, TNFSF11 |
403 | GO:0030431 | 0.05 | 7.00 | 2.50 | 5 | 6 | sleep | SLC29A1, GRIN2A, IL18, OXT, PTGDR |
404 | GO:0097061 | 0.05 | 7.00 | 2.50 | 5 | 6 | dendritic spine organization | ABL2, ARF1, CTTN, ITGA3, PICK1 |
405 | GO:0010742 | 0.05 | 7.00 | 2.50 | 5 | 6 | macrophage derived foam cell differentiation | ALOX15B, CD36, CSF2, PF4, SOAT2 |
406 | GO:0048569 | 0.05 | 7.00 | 2.50 | 5 | 6 | post-embryonic organ development | ERCC1, FBN1, EFEMP1, LDHA, BCL2L11 |
407 | GO:0031646 | 0.05 | 7.00 | 2.50 | 5 | 6 | positive regulation of neurological system process | HGF, NRG1, P2RX3, PTAFR, RNF10 |
408 | GO:0044346 | 0.05 | 7.00 | 2.50 | 5 | 6 | fibroblast apoptotic process | GAS6, PIK3CG, XRCC2, CUL3, API5 |
409 | GO:0050901 | 0.05 | 7.00 | 2.50 | 5 | 6 | leukocyte tethering or rolling | ITGB1, SELE, SELP, SELPLG, MADCAM1 |
410 | GO:0060561 | 0.05 | 7.00 | 2.50 | 5 | 6 | apoptotic process involved in morphogenesis | CRYAB, PPP2R1B, FZD5, HAND2, BCL2L11 |
411 | GO:0060914 | 0.05 | 7.00 | 2.50 | 5 | 6 | heart formation | BMP4, BMPR1A, RBPJ, SMARCD3, IFT88 |
412 | GO:0001759 | 0.00 | 7.00 | 5.01 | 10 | 12 | organ induction | BMP4, FGF1, FGF3, FGF8, GDNF, HOXC11, HOXD11, SIX1, WNT2, WNT2B |
413 | GO:0003071 | 0.00 | 7.00 | 5.01 | 10 | 12 | renal system process involved in regulation of systemic arterial blood pressure | ADORA1, AGTR2, CYBA, EMP2, F2R, F2RL1, GAS6, GJA5, PCSK5, CYP4F2 |
414 | GO:0006361 | 0.00 | 7.00 | 5.01 | 10 | 12 | transcription initiation from RNA polymerase I promoter | CCNH, ERCC3, MAPK3, TBP, TTF1, UBTF, KAT2B, TAF1C, TAF1B, TAF1A |
415 | GO:0007250 | 0.00 | 7.00 | 5.01 | 10 | 12 | activation of NF-kappaB-inducing kinase activity | CHI3L1, IRAK1, TRAF2, IKBKG, TNFRSF10B, TNFRSF10A, TRAF4, TNFSF15, MALT1, COPS8 |
416 | GO:0010592 | 0.00 | 7.00 | 5.01 | 10 | 12 | positive regulation of lamellipodium assembly | AQP1, DNM2, RAC1, RAC2, CLRN1, WNT1, HDAC4, ARPC2, WASF2, TWF2 |
417 | GO:0014829 | 0.00 | 7.00 | 5.01 | 10 | 12 | vascular smooth muscle contraction | ACTA2, BBS2, CHRM1, CHRM3, EDN2, EDN3, EDNRA, EDNRB, PIK3C2A, SLC8A1 |
418 | GO:0035574 | 0.00 | 7.00 | 5.01 | 10 | 12 | histone H4-K20 demethylation | HIST1H4I, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L |
419 | GO:0035909 | 0.00 | 7.00 | 5.01 | 10 | 12 | aorta morphogenesis | COL3A1, EYA1, FGF8, HES1, RBPJ, PROX1, SIX1, SOX4, SRF, SEC24B |
420 | GO:0036336 | 0.00 | 7.00 | 5.01 | 10 | 12 | dendritic cell migration | C1QBP, CDC42, CCR1, CCR5, EPS8, GAS6, PIK3CG, CCL21, ARHGEF5, TNFSF18 |
421 | GO:0042276 | 0.00 | 7.00 | 5.01 | 10 | 12 | error-prone translesion synthesis | REV3L, RFC1, RFC2, RFC3, RFC4, RFC5, RPA3, RPS27A, UBB, MAD2L2 |
422 | GO:0045606 | 0.00 | 7.00 | 5.01 | 10 | 12 | positive regulation of epidermal cell differentiation | ALOX15B, ATOH1, BMP4, CYP27B1, SFN, PTCH1, SFRP4, VDR, PTCH2, TRIM16 |
423 | GO:0060009 | 0.00 | 7.00 | 5.01 | 10 | 12 | Sertoli cell development | ATRX, ESR1, HSD17B4, ICAM1, NTRK1, RAB13, ARID4A, SDC1, SOX9, AKAP9 |
424 | GO:0060334 | 0.00 | 7.00 | 5.01 | 10 | 12 | regulation of interferon-gamma-mediated signaling pathway | HPX, HSP90AB1, IFNG, IFNGR1, PTPN1, PTPN6, SUMO1, NR1H2, SOCS3, CDC37 |
425 | GO:0071380 | 0.00 | 7.00 | 5.01 | 10 | 12 | cellular response to prostaglandin E stimulus | ADCY6, GNAS, GNB1, P2RY4, P2RY6, PRKAA1, PRKCE, PTGER4, TNFSF4, ADAMTS1 |
426 | GO:0009303 | 0.05 | 7.00 | 2.50 | 5 | 6 | rRNA transcription | ANG, GTF3A, BRF1, SMARCA4, TAF1B |
427 | GO:0014048 | 0.05 | 7.00 | 2.50 | 5 | 6 | regulation of glutamate secretion | AVP, CCK, NTSR1, P2RX7, SNCA |
428 | GO:0032369 | 0.05 | 7.00 | 2.50 | 5 | 6 | negative regulation of lipid transport | APOC2, CRY1, ITGAV, SHH, NR1H2 |
429 | GO:0001547 | 0.05 | 6.99 | 2.50 | 5 | 6 | antral ovarian follicle growth | CCNE1, EREG, ESR1, PTGER4, ZP3 |
430 | GO:0002087 | 0.05 | 6.99 | 2.50 | 5 | 6 | regulation of respiratory gaseous exchange by neurological system process | ADORA1, ATP1A2, GLRA1, GLS, PHOX2B |
431 | GO:0003183 | 0.05 | 6.99 | 2.50 | 5 | 6 | mitral valve morphogenesis | ACVR1, EFNA1, SOX4, TWIST1, DCHS1 |
432 | GO:0003272 | 0.05 | 6.99 | 2.50 | 5 | 6 | endocardial cushion formation | BMPR1A, FGF8, RBPJ, SNAI2, DCHS1 |
433 | GO:0003339 | 0.05 | 6.99 | 2.50 | 5 | 6 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis | GDNF, CITED1, PAX2, SALL1, PAX8 |
434 | GO:0003357 | 0.05 | 6.99 | 2.50 | 5 | 6 | noradrenergic neuron differentiation | PHOX2A, SOX4, SOX11, PHOX2B, HAND2 |
435 | GO:0005984 | 0.05 | 6.99 | 2.50 | 5 | 6 | disaccharide metabolic process | GAA, B4GALT1, IDUA, MGAM, TREH |
436 | GO:0006167 | 0.05 | 6.99 | 2.50 | 5 | 6 | AMP biosynthetic process | ADK, ADSL, ADSS, APRT, PRPS2 |
437 | GO:0006925 | 0.05 | 6.99 | 2.50 | 5 | 6 | inflammatory cell apoptotic process | ANXA1, CDKN2A, IFNG, ITPKB, ST6GAL1 |
438 | GO:0007158 | 0.05 | 6.99 | 2.50 | 5 | 6 | neuron cell-cell adhesion | ASTN1, TNR, NRXN3, NRXN1, NRXN2 |
439 | GO:0007183 | 0.05 | 6.99 | 2.50 | 5 | 6 | SMAD protein complex assembly | SMAD1, SMAD3, SMAD6, PPM1A, ZFYVE9 |
440 | GO:0007263 | 0.05 | 6.99 | 2.50 | 5 | 6 | nitric oxide mediated signal transduction | AGTR2, CD36, FPR1, GUCY1B3, SPINK1 |
441 | GO:0008340 | 0.05 | 6.99 | 2.50 | 5 | 6 | determination of adult lifespan | ATM, GHRHR, IDE, PRDM2, COQ7 |
442 | GO:0009221 | 0.05 | 6.99 | 2.50 | 5 | 6 | pyrimidine deoxyribonucleotide biosynthetic process | DTYMK, DUT, SHMT1, TYMS, TBPL1 |
443 | GO:0010934 | 0.05 | 6.99 | 2.50 | 5 | 6 | macrophage cytokine production | CD36, CD74, GAS6, SEMA7A, SPON2 |
444 | GO:0014041 | 0.05 | 6.99 | 2.50 | 5 | 6 | regulation of neuron maturation | BCL2, EDNRB, OPA1, RAC1, RAC3 |
445 | GO:0014733 | 0.05 | 6.99 | 2.50 | 5 | 6 | regulation of skeletal muscle adaptation | CAMK2G, GTF2I, IGFBP5, TNNC1, TNNT1 |
446 | GO:0014857 | 0.05 | 6.99 | 2.50 | 5 | 6 | regulation of skeletal muscle cell proliferation | ANGPT1, SHH, SIX1, STAT3, CFLAR |
447 | GO:0015886 | 0.05 | 6.99 | 2.50 | 5 | 6 | heme transport | ABCB7, HPX, HRG, ABCG2, ABCB6 |
448 | GO:0016264 | 0.05 | 6.99 | 2.50 | 5 | 6 | gap junction assembly | CTNNA1, ACE, GJA5, GJB1, GJB2 |
449 | GO:0019043 | 0.05 | 6.99 | 2.50 | 5 | 6 | establishment of viral latency | HMGA1, XRCC4, BANF1, CREB3, PSIP1 |
450 | GO:0021554 | 0.05 | 6.99 | 2.50 | 5 | 6 | optic nerve development | CHRNB2, LPAR1, KCNA2, PAX2, RPL24 |
451 | GO:0021604 | 0.05 | 6.99 | 2.50 | 5 | 6 | cranial nerve structural organization | EGR2, KCNA2, PAX2, SEMA3F, SEMA3A |
452 | GO:0021903 | 0.05 | 6.99 | 2.50 | 5 | 6 | rostrocaudal neural tube patterning | EN1, FGF8, HES1, WNT1, ATP6AP2 |
453 | GO:0022027 | 0.05 | 6.99 | 2.50 | 5 | 6 | interkinetic nuclear migration | HHEX, PCM1, TACC1, TACC3, TACC2 |
454 | GO:0023041 | 0.05 | 6.99 | 2.50 | 5 | 6 | neuronal signal transduction | CLU, KCNA1, P2RY11, NRXN1, OLFM1 |
455 | GO:0031340 | 0.05 | 6.99 | 2.50 | 5 | 6 | positive regulation of vesicle fusion | AKT2, ANXA1, ANXA2, SYT1, C2CD5 |
456 | GO:0032230 | 0.05 | 6.99 | 2.50 | 5 | 6 | positive regulation of synaptic transmission, GABAergic | CA2, CA7, PRKCE, TAC1, HAP1 |
457 | GO:0032367 | 0.05 | 6.99 | 2.50 | 5 | 6 | intracellular cholesterol transport | ABCA1, ABCA2, SCP2, STAR, ABCG1 |
458 | GO:0033278 | 0.05 | 6.99 | 2.50 | 5 | 6 | cell proliferation in midbrain | RYK, WNT1, WNT2, FZD3, FZD6 |
459 | GO:0033623 | 0.05 | 6.99 | 2.50 | 5 | 6 | regulation of integrin activation | CDH17, PTGER4, SELP, FARP2, CXCL13 |
460 | GO:0034384 | 0.05 | 6.99 | 2.50 | 5 | 6 | high-density lipoprotein particle clearance | APOA1, APOC2, SCARB1, GPLD1, LIPG |
461 | GO:0035584 | 0.05 | 6.99 | 2.50 | 5 | 6 | calcium-mediated signaling using intracellular calcium source | KDR, NTRK2, PRKACA, RYR2, SELP |
462 | GO:0035646 | 0.05 | 6.99 | 2.50 | 5 | 6 | endosome to melanosome transport | AP1G1, CD63, AP1M1, AP3D1, RAB32 |
463 | GO:0038092 | 0.05 | 6.99 | 2.50 | 5 | 6 | nodal signaling pathway | ACVR1B, SMAD3, SHH, ZIC2, CITED2 |
464 | GO:0040015 | 0.05 | 6.99 | 2.50 | 5 | 6 | negative regulation of multicellular organism growth | ADRB2, BBS2, GNAS, PTCH1, RAI1 |
465 | GO:0042045 | 0.05 | 6.99 | 2.50 | 5 | 6 | epithelial fluid transport | AQP1, CSF2, EDNRB, ITPR1, AHCYL1 |
466 | GO:0042178 | 0.05 | 6.99 | 2.50 | 5 | 6 | xenobiotic catabolic process | CRYZ, ACSL1, GSTM1, GSTM2, GSTO1 |
467 | GO:0042428 | 0.05 | 6.99 | 2.50 | 5 | 6 | serotonin metabolic process | ATP2B2, DDC, GRIN2A, PDE1B, SRD5A1 |
468 | GO:0042447 | 0.05 | 6.99 | 2.50 | 5 | 6 | hormone catabolic process | ACE, DIO3, IDE, UGT2B4, HSD17B6 |
469 | GO:0042473 | 0.05 | 6.99 | 2.50 | 5 | 6 | outer ear morphogenesis | EYA1, MAPK3, SALL1, TWIST1, PRKRA |
470 | GO:0042791 | 0.05 | 6.99 | 2.50 | 5 | 6 | 5S class rRNA transcription from RNA polymerase III type 1 promoter | GTF3C1, GTF3C2, GTF3C5, GTF3C4, GTF3C3 |
471 | GO:0042797 | 0.05 | 6.99 | 2.50 | 5 | 6 | tRNA transcription from RNA polymerase III promoter | GTF3C1, GTF3C2, GTF3C5, GTF3C4, GTF3C3 |
472 | GO:0044126 | 0.05 | 6.99 | 2.50 | 5 | 6 | regulation of growth of symbiont in host | CD36, CTSG, IFNG, IL10, OSBP |
473 | GO:0044144 | 0.05 | 6.99 | 2.50 | 5 | 6 | modulation of growth of symbiont involved in interaction with host | CD36, CTSG, IFNG, IL10, OSBP |
474 | GO:0044793 | 0.05 | 6.99 | 2.50 | 5 | 6 | negative regulation by host of viral process | APCS, LTF, PARK2, VAPB, VAPA |
475 | GO:0044794 | 0.05 | 6.99 | 2.50 | 5 | 6 | positive regulation by host of viral process | CAV2, STOM, PPIB, VAPB, VAPA |
476 | GO:0045019 | 0.05 | 6.99 | 2.50 | 5 | 6 | negative regulation of nitric oxide biosynthetic process | ACP5, TSPO, IL10, PTGIS, RGN |
477 | GO:0045136 | 0.05 | 6.99 | 2.50 | 5 | 6 | development of secondary sexual characteristics | AREG, BAX, B4GALT1, STAT5B, PHB2 |
478 | GO:0045759 | 0.05 | 6.99 | 2.50 | 5 | 6 | negative regulation of action potential | CAV3, CHRNB2, CNR1, CNR2, SUMO1 |
479 | GO:0045764 | 0.05 | 6.99 | 2.50 | 5 | 6 | positive regulation of cellular amino acid metabolic process | COMT, GATA3, HPN, PAX8, NR1H4 |
480 | GO:0046719 | 0.05 | 6.99 | 2.50 | 5 | 6 | regulation by virus of viral protein levels in host cell | DDB1, IFIT1, STAU1, DYNLT1, VAPB |
481 | GO:0048570 | 0.05 | 6.99 | 2.50 | 5 | 6 | notochord morphogenesis | EFNA1, EPHA2, T, KDM6A, WNT11 |
482 | GO:0048757 | 0.05 | 6.99 | 2.50 | 5 | 6 | pigment granule maturation | AP1G1, CD63, AP1M1, AP3D1, RAB32 |
483 | GO:0051712 | 0.05 | 6.99 | 2.50 | 5 | 6 | positive regulation of killing of cells of other organism | BAD, F2RL1, FCER2, IFNG, BCL2L11 |
484 | GO:0060158 | 0.05 | 6.99 | 2.50 | 5 | 6 | phospholipase C-activating dopamine receptor signaling pathway | GNA15, GNAQ, GPR52, SLC9A3R1, GNA14 |
485 | GO:0060281 | 0.05 | 6.99 | 2.50 | 5 | 6 | regulation of oocyte development | IGF1, PDE3A, PPP2R1A, AURKA, PDE5A |
486 | GO:0060315 | 0.05 | 6.99 | 2.50 | 5 | 6 | negative regulation of ryanodine-sensitive calcium-release channel activity | CALM3, CASQ2, GSTM2, GSTO1, TRDN |
487 | GO:0060406 | 0.05 | 6.99 | 2.50 | 5 | 6 | positive regulation of penile erection | EDNRB, OXT, P2RY1, P2RY2, VIP |
488 | GO:0060453 | 0.05 | 6.99 | 2.50 | 5 | 6 | regulation of gastric acid secretion | KCNQ1, OXT, SGK1, UCN, TRPV1 |
489 | GO:0060462 | 0.05 | 6.99 | 2.50 | 5 | 6 | lung lobe development | BMP4, GATA4, IGF1, SHH, SEC24B |
490 | GO:0060546 | 0.05 | 6.99 | 2.50 | 5 | 6 | negative regulation of necroptotic process | SLC25A4, BIRC3, CASP8, ARHGEF2, RBCK1 |
491 | GO:0060836 | 0.05 | 6.99 | 2.50 | 5 | 6 | lymphatic endothelial cell differentiation | ACVR2B, ACVRL1, BMPR2, PROX1, NR2F2 |
492 | GO:0060973 | 0.05 | 6.99 | 2.50 | 5 | 6 | cell migration involved in heart development | SNAI2, TWIST1, DCHS1, HAND2, BVES |
493 | GO:0070886 | 0.05 | 6.99 | 2.50 | 5 | 6 | positive regulation of calcineurin-NFAT signaling cascade | NRG1, IGF1, SLC9A1, SLC12A1, AKAP6 |
494 | GO:0071236 | 0.05 | 6.99 | 2.50 | 5 | 6 | cellular response to antibiotic | HMBS, IL1B, SCN3A, SLC9A1, STAR |
495 | GO:0071285 | 0.05 | 6.99 | 2.50 | 5 | 6 | cellular response to lithium ion | CDH1, NTS, SHH, SLC18A1, XRCC4 |
496 | GO:0071374 | 0.05 | 6.99 | 2.50 | 5 | 6 | cellular response to parathyroid hormone stimulus | SLC34A1, FGF23, KAT2B, ADAMTS1, HDAC4 |
497 | GO:0071801 | 0.05 | 6.99 | 2.50 | 5 | 6 | regulation of podosome assembly | BLK, CSF2, HCK, MAPK8, ARHGEF5 |
498 | GO:0072217 | 0.05 | 6.99 | 2.50 | 5 | 6 | negative regulation of metanephros development | BMP4, CITED1, PAX2, SALL1, PAX8 |
499 | GO:0086015 | 0.05 | 6.99 | 2.50 | 5 | 6 | SA node cell action potential | GJA5, KCNA5, RYR2, SCN5A, HCN4 |
500 | GO:0086070 | 0.05 | 6.99 | 2.50 | 5 | 6 | SA node cell to atrial cardiac muscle cell communication | GJA5, KCNA5, RYR2, SCN5A, HCN4 |
501 | GO:0098739 | 0.05 | 6.99 | 2.50 | 5 | 6 | import across plasma membrane | ATP1A2, FXYD2, SLC2A5, SLC9A1, TRPM2 |
502 | GO:1903624 | 0.05 | 6.99 | 2.50 | 5 | 6 | regulation of DNA catabolic process | BAX, CDKN2A, DFFA, RGN, AIFM1 |
503 | GO:2000020 | 0.05 | 6.99 | 2.50 | 5 | 6 | positive regulation of male gonad development | NR5A1, SOX9, SRY, CITED2, SEMA3A |
504 | GO:2000727 | 0.05 | 6.99 | 2.50 | 5 | 6 | positive regulation of cardiac muscle cell differentiation | BMP4, EFNB2, NRG1, RBPJ, AKAP6 |
505 | GO:2000794 | 0.05 | 6.99 | 2.50 | 5 | 6 | regulation of epithelial cell proliferation involved in lung morphogenesis | CDC42, FGF7, SRSF6, SOX9, WNT2 |
506 | GO:2001223 | 0.05 | 6.99 | 2.50 | 5 | 6 | negative regulation of neuron migration | COL3A1, NRG1, STAT3, OLFM1, NRG3 |
507 | GO:0051270 | 0.00 | 6.96 | 9.36 | 19 | 23 | regulation of cellular component movement | ATP1A2, DSC2, DSP, GATA4, B4GALT1, GJA5, JUP, KCNJ2, PDE4B, PDE4D, PLN, RYR2, SCN5A, TNNC1, TNNT2, SUMO1, DNAH11, HAP1, TBR1 |
508 | GO:0038061 | 0.00 | 6.88 | 19.59 | 39 | 47 | NIK/NF-kappaB signaling | ALK, BIRC3, CHUK, PPP4C, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RELB, RPS27A, SKP1, UBB, CUL1, UBA3, PSMF1, PSMD6, PSME3 |
509 | GO:0042542 | 0.00 | 6.83 | 14.57 | 29 | 35 | response to hydrogen peroxide | ADA, AREG, BAD, BCL2, CAT, COL1A1, CRYAB, DUSP1, EEF2, GJA3, GPX1, HBA1, HBA2, HP, JUN, KCNA5, KPNA4, LDHA, OLR1, PPP2CB, SDC1, SHC1, SLC8A1, SOD1, STAR, FOSL1, ADAM9, TXNIP, PRDX3 |
510 | GO:0031670 | 0.00 | 6.67 | 9.59 | 19 | 23 | cellular response to nutrient | ATP2B1, BGLAP, CCNE1, COL1A1, CYP24A1, CYP27B1, GAS6, TNC, ITGB1, PAWR, PENK, PIM1, PTN, SNAI2, VDR, FGF23, TRIM24, ADAMTS1, NR1H4 |
511 | GO:1901532 | 0.00 | 6.66 | 9.60 | 19 | 23 | regulation of hematopoietic progenitor cell differentiation | GABPA, PRMT1, HES1, KDR, PF4, EIF2AK2, SOS1, SOS2, ZNF16, HIST1H4I, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L |
512 | GO:0030819 | 0.00 | 6.63 | 16.69 | 33 | 40 | positive regulation of cAMP biosynthetic process | ABCA1, ADCY7, ADCYAP1R1, ADORA2A, ADRB2, AVP, AVPR2, CALCR, CALM3, EDNRA, FSHR, GCG, GHRH, GHRHR, GLP1R, GNAL, GNAS, INSL3, NTRK1, NTRK2, P2RY11, PRKCA, PTGER4, PTHLH, RAF1, UCN, VIP, VIPR2, WFS1, CALCRL, RAMP2, CAP2, CAP1 |
513 | GO:0002687 | 0.00 | 6.58 | 7.07 | 14 | 17 | positive regulation of leukocyte migration | ICAM1, ITGA2, ITGA4, KITLG, PAWR, PTAFR, PTGER4, CCL20, CCL24, SELE, SELP, ZP3, MADCAM1, TNFRSF18 |
514 | GO:0032890 | 0.00 | 6.55 | 7.08 | 14 | 17 | regulation of organic acid transport | ARG1, ATP1A2, AVP, CCK, SEPT2, NTSR1, OXT, P2RX4, P2RX7, P2RY2, SNCA, SYK, TNFSF11, SLC38A3 |
515 | GO:0044062 | 0.00 | 6.54 | 7.09 | 14 | 17 | regulation of excretion | ADORA1, AGTR2, ANPEP, AVP, AVPR2, COMT, EDNRB, KNG1, OXT, PTGER4, STC1, TAC1, SLC9A3R1, CORIN |
516 | GO:0046688 | 0.00 | 6.54 | 7.09 | 14 | 17 | response to copper ion | ALDOB, AQP1, ATP5D, ATP7B, BAX, CP, ICAM1, IL1A, LCAT, PAM, S100A13, SNCA, SOD1, SORD |
517 | GO:0071305 | 0.00 | 6.54 | 7.09 | 14 | 17 | cellular response to vitamin D | ATP2B1, BGLAP, CYP24A1, CYP27B1, TNC, ITGB1, PENK, PIM1, PTN, SNAI2, VDR, FGF23, TRIM24, ADAMTS1 |
518 | GO:1901021 | 0.00 | 6.54 | 7.09 | 14 | 17 | positive regulation of calcium ion transmembrane transporter activity | BMP4, CALM3, GSTM2, RYR2, S100A1, SLC9A1, SUMO1, HAP1, RGN, GSTO1, AKAP6, KCNE2, KCNE3, TRDN |
519 | GO:1901522 | 0.00 | 6.54 | 7.09 | 14 | 17 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus | ATF4, RUNX2, DLX5, EP300, HIF1A, FOXA2, RBPJ, SMAD1, RXRA, RXRG, USF1, USF2, VEGFA, CREB3 |
520 | GO:0045669 | 0.00 | 6.46 | 11.69 | 23 | 28 | positive regulation of osteoblast differentiation | ACVR1, ACVR2A, ACVR2B, ATP6AP1, BMP4, BMP6, BMPR1A, BMPR2, RUNX2, DLX5, GNAS, HGF, IGF1, ILK, JUND, LTF, SMAD1, DDR2, PRKD1, PTGER4, SOX11, TP63, PDLIM7 |
521 | GO:0030574 | 0.00 | 6.43 | 16.28 | 32 | 39 | collagen catabolic process | ADAM10, COL1A1, COL2A1, COL3A1, COL4A3, COL4A4, COL4A5, COL4A6, COL5A1, COL5A2, COL6A2, COL6A3, COL9A1, COL9A3, COL10A1, COL11A1, COL12A1, COL16A1, COL17A1, COL19A1, CTSD, CTSK, CTSS, FAP, ITGB1, PEPD, KLK6, COL14A1, ADAM15, ADAM9, ADAMTS3, ADAMTS2 |
522 | GO:0007093 | 0.01 | 6.36 | 4.56 | 9 | 11 | mitotic cell cycle checkpoint | BCL2L1, DLG1, PRCC, RB1, RPL24, SMC1A, MAD2L1BP, KNTC1, ZWINT |
523 | GO:0033002 | 0.00 | 6.35 | 18.33 | 36 | 44 | muscle cell proliferation | ALOX12, ANG, BMP4, COMT, CYBA, HBEGF, S1PR1, EDNRA, EREG, ESR1, FLT1, HIF1A, HMGCR, IFNG, IGF1, IGFBP3, IGFBP5, IL13, ILK, IRAK1, ITGA2, JUN, OGN, ORC1, PTAFR, CX3CL1, SHC1, SKP2, STAT5B, TNFAIP3, VIP, VIPR2, KLF4, HDAC4, CALCRL, TRIB1 |
524 | GO:0035265 | 0.01 | 6.33 | 4.57 | 9 | 11 | organ growth | ACVR2B, ADRA1B, BCL2, ESR1, FGF7, IGF1, SHH, SOX9, UBE3A |
525 | GO:0002755 | 0.00 | 6.32 | 13.77 | 27 | 33 | MyD88-dependent toll-like receptor signaling pathway | BTK, CD14, CD36, CHUK, ATF2, DUSP4, DUSP7, ELK1, IRAK1, IRAK2, IRF1, JUN, PPP2R5D, MAPK3, MAPK8, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, UBB, UBE2V1, CUL1, IKBKG, RIPK2, RPS6KA5, TNIP1 |
526 | GO:0071300 | 0.00 | 6.32 | 13.77 | 27 | 33 | cellular response to retinoic acid | ABCA1, ABL2, AQP1, COL1A1, BRINP1, PHC1, EPHA3, TNC, KRT13, NTRK3, PAX2, SERPINF1, PTK7, RARA, SLC6A4, SOX9, T, WNT2, WNT11, ZNF35, FZD4, FZD7, OGT, ALDH1A2, KLF4, FZD10, TWF2 |
527 | GO:0014896 | 0.00 | 6.32 | 9.17 | 18 | 22 | muscle hypertrophy | ADK, CDK9, CYBA, GATA6, IGF1, IGFBP5, P2RX4, PRKCA, RGS2, RYR2, SLC9A1, TRPC3, CSRP3, AKAP1, PDE5A, KDM4A, HDAC4, AKAP13 |
528 | GO:0003300 | 0.01 | 6.32 | 4.58 | 9 | 11 | cardiac muscle hypertrophy | AGTR2, GATA4, GATA6, RYR2, CSRP3, SORBS2, KDM4A, HDAC4, PDLIM5 |
529 | GO:0034113 | 0.00 | 6.31 | 9.18 | 18 | 22 | heterotypic cell-cell adhesion | APOA1, CD2, CD58, CXADR, DSC2, DSP, IL1RN, ITGA4, ITGA5, ITGA7, ITGAD, ITGAV, ITGAX, ITGB1, JUP, NRCAM, MADCAM1, KLF4 |
530 | GO:0061053 | 0.01 | 6.31 | 4.58 | 9 | 11 | somite development | IHH, PTCH1, RAD51B, RBBP6, SHH, SIX1, SOX11, WNT1, WNT11 |
531 | GO:0001954 | 0.01 | 6.31 | 4.58 | 9 | 11 | positive regulation of cell-matrix adhesion | CD36, CDK6, EMP2, EPHA1, ILK, PRKCZ, CCL21, CCL25, VEGFC |
532 | GO:0001974 | 0.00 | 6.31 | 9.18 | 18 | 22 | blood vessel remodeling | ACVR2B, ACVRL1, ADRA1B, AGTR2, AXL, BAX, BMPR2, DBH, ACE, ERG, FGF8, FLT4, HRG, IGF1, RBPJ, ITGA4, CSRP3, ATG5 |
533 | GO:0002548 | 0.00 | 6.31 | 9.18 | 18 | 22 | monocyte chemotaxis | ANXA1, CCR1, FLT1, SERPINE1, RPS19, S100A12, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, XCL2, TNFSF11, TNFSF18, SLIT2, CREB3 |
534 | GO:0045070 | 0.00 | 6.31 | 9.18 | 18 | 22 | positive regulation of viral genome replication | ADAR, ADARB1, CD28, DDB1, DDX3X, STOM, IFIT1, PPIB, PPID, SRPK2, STAU1, TARBP2, TOP2A, VAPB, VAPA, PPIE, PPIH, TRIM38 |
535 | GO:0072350 | 0.00 | 6.31 | 9.18 | 18 | 22 | tricarboxylic acid metabolic process | ACLY, ACO1, ASS1, DLD, GLUD1, IDH1, IDH3A, MDH1, MDH2, OGDH, SDHB, SDHC, SDHD, SLC34A1, STAT5B, SUCLG2, SUCLG1, SUCLA2 |
536 | GO:0045844 | 0.01 | 6.31 | 4.59 | 9 | 11 | positive regulation of striated muscle tissue development | BMP4, CCNB1, EFNB2, GATA4, GATA6, NRG1, RBPJ, WNT2, AKAP6 |
537 | GO:0019433 | 0.01 | 6.30 | 4.59 | 9 | 11 | triglyceride catabolic process | CPS1, FABP2, FABP6, FABP7, LIPE, PPP1CA, PRKACA, PRKACB, PRKACG |
538 | GO:0002026 | 0.01 | 6.30 | 4.59 | 9 | 11 | regulation of the force of heart contraction | ATP1A2, GAA, IFNG, PLN, PRKCA, RYR2, SLC8A1, SLC9A1, CSRP3 |
539 | GO:0061217 | 0.01 | 6.30 | 4.59 | 9 | 11 | regulation of mesonephros development | AGTR2, GDNF, PAX2, SALL1, SOX9, VEGFA, WNT2B, PAX8, SIX2 |
540 | GO:0006349 | 0.01 | 6.30 | 4.59 | 9 | 11 | regulation of gene expression by genetic imprinting | BRCA1, DNMT3A, DNMT3B, IGF2, KCNQ1, ARID4A, EED, DIRAS3, CTCF |
541 | GO:0006582 | 0.01 | 6.30 | 4.59 | 9 | 11 | melanin metabolic process | ASIP, BCL2, CDH3, CTNS, CITED1, TRPC1, TYRP1, RAPGEF2, ZEB2 |
542 | GO:0010460 | 0.01 | 6.30 | 4.59 | 9 | 11 | positive regulation of heart rate | ADA, ADRA1B, EDN2, EDN3, HRC, KCNQ1, PDE4D, RYR2, TACR3 |
543 | GO:0031639 | 0.01 | 6.30 | 4.59 | 9 | 11 | plasminogen activation | APOH, DHCR24, F12, FGA, FGG, HPN, KLKB1, SERPINE1, CLEC3B |
544 | GO:0031958 | 0.01 | 6.30 | 4.59 | 9 | 11 | corticosteroid receptor signaling pathway | ARNTL, CRY1, CRY2, PER1, PHB, PPP5C, YWHAH, CLOCK, RBM14 |
545 | GO:0045086 | 0.01 | 6.30 | 4.59 | 9 | 11 | positive regulation of interleukin-2 biosynthetic process | CD4, CD28, CD80, CD86, IL1A, IL1B, PRKCQ, STAT5B, GLMN |
546 | GO:0051000 | 0.01 | 6.30 | 4.59 | 9 | 11 | positive regulation of nitric-oxide synthase activity | AGTR2, CALM3, SCARB1, DHFR, ESR1, FCER2, HIF1A, INS, KRAS |
547 | GO:0060231 | 0.01 | 6.30 | 4.59 | 9 | 11 | mesenchymal to epithelial transition | BMP4, GATA3, GDNF, CITED1, PAX2, SALL1, PAX8, FZD7, SIX2 |
548 | GO:0072148 | 0.01 | 6.30 | 4.59 | 9 | 11 | epithelial cell fate commitment | ACVR1, ATOH1, FGFR3, GATA4, HES1, RBPJ, PROX1, RARA, NR2F2 |
549 | GO:0090190 | 0.01 | 6.30 | 4.59 | 9 | 11 | positive regulation of branching involved in ureteric bud morphogenesis | AGTR2, GDNF, PAX2, SALL1, SIX1, SOX9, VEGFA, WNT2B, PAX8 |
550 | GO:0097205 | 0.01 | 6.30 | 4.59 | 9 | 11 | renal filtration | ADORA1, AQP1, EDNRA, EMP2, F2R, F2RL1, GAS6, GJA5, ITGA3 |
551 | GO:1902176 | 0.01 | 6.30 | 4.59 | 9 | 11 | negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | GPX1, HIF1A, HSPB1, INS, PARK2, SOD2, VNN1, BAG5, TRAP1 |
552 | GO:0055117 | 0.00 | 6.19 | 11.25 | 22 | 27 | regulation of cardiac muscle contraction | ADORA1, ADRA1B, CALM3, CASQ2, CAV3, CTGF, GSTM2, HRC, KCNQ1, SMAD7, P2RX4, PIK3CG, PRKACA, RGS2, SCN10A, SLC8A1, SLC9A1, UCN, PDE5A, GSTO1, HDAC4, HCN4 |
553 | GO:0034097 | 0.00 | 6.16 | 14.54 | 29 | 36 | response to cytokine | ACP5, ADAM10, AVPR2, BCL2, BCL2L1, CCNE1, CD14, COL3A1, CYP27B1, ACSL4, GSS, ITIH4, JUN, JUNB, JUND, AFF3, PGGT1B, RARA, SLC11A1, SPARC, SRF, TYMS, SCGB1A1, FOSL1, ADAM9, ALDH1A2, KYNU, TRAFD1, ADAMTS13 |
554 | GO:0033993 | 0.00 | 6.13 | 42.68 | 85 | 106 | response to lipid | ABCA2, ACADS, ADCYAP1R1, ADRB2, AGXT, ALDH3A1, ALDOB, ANXA3, APOA1, APOH, AREG, STS, AVP, BAX, BCHE, CCND1, BCL2, BID, BRCA2, C3, CA2, CALCR, CALM3, CD4, CDK4, CDKN1A, CDO1, CRYAB, CTNNA1, CTSV, DTYMK, EEF2, ETS1, F7, FGA, GATA3, GATA6, GIP, GJB2, GOT1, GRN, IDH1, IGF2, IHH, IL1RN, KCNJ11, KRAS, KRT19, LCAT, LDHA, SMAD6, MFGE8, NTSR1, OGG1, PAM, PLN, PSPH, PTPRN, RBBP8, S100B, SDC1, SHC1, SLC9A3, SLIT3, STAT3, AURKA, TACR3, TAT, TRH, UCN, TRIM25, PRDM2, RAB7A, FOSL1, RGS9, MBD4, SLIT2, ABCG1, PTPRU, RAMP2, CITED2, SPTLC1, SLC34A2, TXNIP, SOX30 |
555 | GO:0007254 | 0.00 | 6.11 | 6.65 | 13 | 16 | JNK cascade | DUSP9, IRAK1, IRAK2, MAPK8, PTGER4, RPS27A, UBB, IKBKG, ARHGEF6, RB1CC1, SH2D3C, SH2D3A, TRIB1 |
556 | GO:0002053 | 0.00 | 6.07 | 6.68 | 13 | 16 | positive regulation of mesenchymal cell proliferation | ARHGAP5, BMPR1A, FGF9, IHH, KDR, PRRX1, SHH, SIX1, SOX9, VEGFA, WNT2, TP63, CHRD |
557 | GO:0002891 | 0.00 | 6.07 | 6.68 | 13 | 16 | positive regulation of immunoglobulin mediated immune response | C3, CD28, CD40, FCER1A, FCER1G, FCER2, HPX, IFNG, XCL1, TNFSF4, UNG, WHSC1, TNFSF13 |
558 | GO:0006099 | 0.00 | 6.07 | 6.68 | 13 | 16 | tricarboxylic acid cycle | ACO1, DLD, IDH1, IDH3A, MDH1, MDH2, OGDH, SDHB, SDHC, SDHD, SUCLG2, SUCLG1, SUCLA2 |
559 | GO:0018146 | 0.00 | 6.07 | 6.68 | 13 | 16 | keratan sulfate biosynthetic process | B4GALT1, LUM, CHST6, OMD, OGN, B4GALT4, B4GALT3, B4GALT6, B4GALT5, B3GNT3, ST3GAL6, SLC35D2, KERA |
560 | GO:0048485 | 0.00 | 6.07 | 6.68 | 13 | 16 | sympathetic nervous system development | PHOX2A, GATA3, GDNF, NTRK1, SEMA3F, SOX4, SOX11, FZD3, TP63, NRP2, PHOX2B, HAND2, SEMA3A |
561 | GO:0048662 | 0.00 | 6.07 | 6.68 | 13 | 16 | negative regulation of smooth muscle cell proliferation | ANG, COMT, ESR1, IFNG, IGFBP3, IGFBP5, ILK, OGN, TNFAIP3, VIP, VIPR2, KLF4, TRIB1 |
562 | GO:0061418 | 0.00 | 6.07 | 6.68 | 13 | 16 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | ARNT, BACH1, EP300, HIF1A, RBPJ, RPS27A, UBB, UBE2D1, UBE2D2, VEGFA, CUL2, RBX1, CITED2 |
563 | GO:0071392 | 0.00 | 6.07 | 6.68 | 13 | 16 | cellular response to estradiol stimulus | ESR1, H2AFZ, IGF1, IL10, ITGA2, PAWR, SRD5A1, SSTR2, SSTR3, NRIP1, AIFM1, RAMP3, RUVBL2 |
564 | GO:0071549 | 0.00 | 6.07 | 6.68 | 13 | 16 | cellular response to dexamethasone stimulus | AGTR2, AQP1, ARG1, ASS1, CASP9, DNMT3B, FECH, HMBS, NTS, SERPINF1, SRD5A1, STAR, CBX3 |
565 | GO:0032970 | 0.00 | 6.02 | 8.71 | 17 | 21 | regulation of actin filament-based process | ATP1A2, DSC2, DSP, GATA4, GJA5, JUP, KCNJ2, PDE4B, PDE4D, PLN, RYR2, SCN5A, STC1, TNNC1, TNNT2, SUMO1, CSRP3 |
566 | GO:0051092 | 0.00 | 6.00 | 26.29 | 51 | 63 | positive regulation of NF-kappaB transcription factor activity | ALK, BTK, CAMK2A, CAT, CD40, CHUK, CLU, CTH, EDA, ICAM1, IL1B, INS, IRAK1, IRAK2, KRAS, LTF, NTRK1, PRKCB, PRKCI, PRKD1, PRKCQ, PRKCZ, EIF2AK2, PSMA6, RPS3, RPS27A, S100A8, S100A9, S100A12, TRAF1, TRAF2, UBB, UBE2V1, TRIM25, IKBKG, TNFSF11, TRADD, RIPK1, RIPK2, CFLAR, BCL10, RPS6KA4, TNFSF18, ARHGEF2, RPS6KA5, CLOCK, TRIM22, TRIM38, RBCK1, MALT1, PRDX3 |
567 | GO:0060688 | 0.00 | 5.97 | 8.75 | 17 | 21 | regulation of morphogenesis of a branching structure | AGTR2, ESR1, FGF7, GDNF, HGF, IL1B, TACSTD2, PAX2, PGF, RXRA, SALL1, SHH, SIX1, SNAI2, VEGFA, PAX8, SIX2 |
568 | GO:0032776 | 0.00 | 5.96 | 8.76 | 17 | 21 | DNA methylation on cytosine | H3F3B, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HIST1H3F |
569 | GO:0045907 | 0.00 | 5.96 | 8.76 | 17 | 21 | positive regulation of vasoconstriction | ADRA1B, ADRA2C, AVP, AVPR1B, AVPR2, CD38, DBH, F2R, FGA, FGG, GJA5, HRH1, HRH2, ICAM1, PTAFR, PTGS1, SHC1 |
570 | GO:0031644 | 0.00 | 5.91 | 10.84 | 21 | 26 | regulation of neurological system process | ADORA1, ADRA2C, ADRB2, AVP, CCK, COMT, EDNRB, F2R, GLRA1, GRIN2A, GRM1, HTR2C, IFNG, IL10, NTSR1, OXT, SLC9A1, VIP, EIF2AK3, FIG4, SCN11A |
571 | GO:0071345 | 0.00 | 5.89 | 6.08 | 12 | 15 | cellular response to cytokine stimulus | CD86, CDC5L, CDK9, DPYSL3, ETV3, HCLS1, HMBS, IL13, ITGA4, PDE1B, IL18RAP, AKAP6 |
572 | GO:0007568 | 0.00 | 5.87 | 40.34 | 78 | 97 | aging | ABAT, ADA, ADRB2, ALDH3A1, ALOX12, APOH, ARG1, ASS1, ATP2B1, ATP5G3, BAX, TSPO, SERPING1, CASP9, CAT, CD86, CLU, CNP, CNR1, COL3A1, CP, CRYAB, CTGF, CTNNA1, DCN, DLD, DNMT1, DNMT3A, EDNRA, EDNRB, EEF2, EIF2S1, F3, GSS, HMGCR, IGF1, IGFBP2, IL1B, IL10, IRAK1, JUN, JUND, KRT14, KRT16, KRT33B, KRT83, NTRK1, NTRK2, OGG1, P2RY1, P2RY2, PAX2, PDE4D, SERPINF1, PENK, PRKCQ, PTGS1, PTH1R, RPN2, RXRA, CX3CL1, SHC1, SNCA, SOD2, SREBF1, STAT3, TACR3, TNFRSF1B, TYMS, MADCAM1, EIF2B5, SOCS3, RGN, AURKB, LITAF, KCNE2, CARM1, GJB6 |
573 | GO:0031100 | 0.00 | 5.86 | 12.92 | 25 | 31 | organ regeneration | ANGPT2, ANXA3, APOA1, APOH, CCND1, CCNE1, CDK4, CDKN1A, EIF4A1, F7, FLT3, GAS6, HGF, HMBS, IGF2R, MKI67, NRF1, PGF, PRPS2, SHC1, TYMS, WNT1, NR0B2, SOCS3, PTPRU |
574 | GO:0000183 | 0.00 | 5.85 | 12.94 | 25 | 31 | chromatin silencing at rDNA | H3F3B, PHF2, SUV39H1, TBP, UBTF, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HIST1H3F, TAF1C, TAF1B, TAF1A, BAZ2A |
575 | GO:0038123 | 0.00 | 5.85 | 12.94 | 25 | 31 | toll-like receptor TLR1:TLR2 signaling pathway | BTK, CD14, CD36, CHUK, ATF2, DUSP4, DUSP7, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK3, MAPK8, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, UBB, UBE2V1, CUL1, IKBKG, RIPK2, RPS6KA5 |
576 | GO:0038124 | 0.00 | 5.85 | 12.94 | 25 | 31 | toll-like receptor TLR6:TLR2 signaling pathway | BTK, CD14, CD36, CHUK, ATF2, DUSP4, DUSP7, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK3, MAPK8, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, UBB, UBE2V1, CUL1, IKBKG, RIPK2, RPS6KA5 |
577 | GO:0030801 | 0.00 | 5.78 | 21.28 | 41 | 51 | positive regulation of cyclic nucleotide metabolic process | ABCA1, ADCY7, ADCYAP1R1, ADORA2A, ADRB2, AVP, AVPR2, CALCR, CALM3, EDNRA, FSHR, GCG, GHRH, GHRHR, GLP1R, GNAL, GNAS, GUCA1A, GUCA1B, GUCA2A, GUCA2B, INSL3, NTRK1, NTRK2, P2RY11, PF4, PRKCA, PTGER4, PTHLH, RAF1, RCVRN, UCN, VIP, VIPR2, WFS1, GUCA1C, CALCRL, RAMP2, RAPGEF3, CAP2, CAP1 |
578 | GO:0051047 | 0.01 | 5.72 | 4.12 | 8 | 10 | positive regulation of secretion | ADORA1, AQP1, ACSL3, P2RX4, S100A8, S100A9, TRPV1, CYP4F2 |
579 | GO:0003018 | 0.02 | 5.68 | 4.14 | 8 | 10 | vascular process in circulatory system | ANGPT1, ARHGAP35, PDE3A, PTPRJ, TACR2, VEGFA, SLIT2, RAMP2 |
580 | GO:0001889 | 0.00 | 5.67 | 22.88 | 44 | 55 | liver development | ACAT1, ADA, AK2, AK4, ALDH9A1, ALDOB, ARF6, ARG1, ASNS, ASS1, CCND1, CCNE1, CEBPG, CP, GATA6, HGF, HLX, HMGCL, HMGCS1, HMGCS2, ONECUT1, HES1, IGF2R, JARID2, JUN, SMAD3, NTS, OTC, PHF2, QDPR, RARA, RXRA, SOX9, SP1, SP3, SRD5A1, STAT5B, IFT88, ALDH1A2, ONECUT2, RB1CC1, CITED2, ATG7, SEC63 |
581 | GO:0070372 | 0.02 | 5.67 | 4.14 | 8 | 10 | regulation of ERK1 and ERK2 cascade | EPHA2, EPHA7, EPHB1, ERBB2, PTPN6, RRAS, STYX, SYK |
582 | GO:0046660 | 0.00 | 5.65 | 27.13 | 52 | 65 | female sex differentiation | ACVR1B, ADCYAP1R1, AHR, AMHR2, ANG, AXL, BAX, BCL2, BCL2L1, BMP4, BRCA2, CAPN5, CCNE1, COL9A3, CTNNA1, EREG, ESR1, FANCA, FANCG, FGF7, CENPI, FSHR, NR5A1, GDF9, ICAM1, IDH1, INHA, KDR, KIT, KITLG, PGR, PTGER4, PTPRN, SLIT3, SOD1, SRD5A1, STAT5B, TYRO3, UBB, UBE3A, VEGFA, ZP3, NRIP1, FZD4, TP63, SGPL1, EIF2B4, EIF2B2, EIF2B5, BMP15, SLIT2, ADAMTS1 |
583 | GO:0022612 | 0.00 | 5.64 | 10.40 | 20 | 25 | gland morphogenesis | BCL2, CD44, CDC42, EDA, FGF7, FGF8, HGF, TNC, IGF1, IGF1R, LAMA5, RXRA, SHH, SNAI2, SOX9, TP63, SLC9A3R1, FEM1B, SEMA3A, EDAR |
584 | GO:0014070 | 0.00 | 5.64 | 61.00 | 119 | 151 | response to organic cyclic compound | ABCA2, ACADS, ACAT1, ACP5, ADCYAP1R1, ADRB2, ANGPT2, ANXA3, APOA1, STS, ATP12A, BID, BMP6, BRCA2, TSPO, C3, CA2, CALCR, CALM3, CALU, CD4, CD38, CDK4, CDKN1A, CDKN2D, CHKA, CCR5, COMT, CRYAB, CTGF, CTSV, CYP1A2, DDX1, DTYMK, EDNRA, EDNRB, ETS1, F3, F7, ACSL1, ACSL3, FGF8, GATA3, GATA4, GATA6, KAT2A, GIP, GJB2, GOT1, GRN, HLCS, ICAM1, IDH1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGFBP2, IHH, IL1RN, KCNJ8, KRAS, KRT19, LCAT, LUM, SMAD6, MFGE8, MKI67, NTRK3, TNFRSF11B, OTC, PAM, PLN, PPP2R2A, PRKACB, PRKAR2B, PRKCE, PRKCG, PRKCQ, MAPK3, PSMB2, PSPH, PTGER4, PTGS1, ABCD3, RBBP8, S100B, SELP, SLC9A3, SLIT3, STAT5B, AURKA, TAC1, TAF2, TAT, TRH, TSHB, UCN, SCGB1A1, TRIM25, PRDM2, PEA15, ADAM9, RIPK2, RGS9, ALDH1A2, MBD4, KYNU, SOCS3, DDX21, SLIT2, PTPRU, RAMP2, CITED2, SLC34A2, TXNIP, SOX30 |
585 | GO:0048013 | 0.00 | 5.64 | 22.95 | 44 | 55 | ephrin receptor signaling pathway | ACTB, ACTG1, ADAM10, AP2A1, AP2B1, CDC42, CHN1, AP2M1, AP2S1, DNM1, EFNA1, EFNA3, EFNA4, EFNA5, EFNB2, EPHA2, EPHA1, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, FYN, RBPJ, LIMK1, NTRK1, NTRK3, RAC1, SDC2, SDCBP, ITSN1, ARHGEF7, KALRN, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, VAV3, ARPC1A |
586 | GO:0051928 | 0.00 | 5.63 | 10.41 | 20 | 25 | positive regulation of calcium ion transport | ATP2B2, TSPO, CAMK2A, CCR1, GCG, FFAR1, RYR2, S100A1, SLC9A1, STC1, SUMO1, UCN, WFS1, ZP3, RGN, KCNE2, KCNE3, RAPGEF3, CREB3, CLDN16 |
587 | GO:0002027 | 0.00 | 5.63 | 8.32 | 16 | 20 | regulation of heart rate | AGTR2, CACNA1E, CALM3, CASQ2, CAV3, OXT, PLN, PRKACA, SCN10A, SLC8A1, SNTA1, SREBF1, TAC1, IRX5, SEMA3A, BVES |
588 | GO:0030593 | 0.00 | 5.63 | 12.50 | 24 | 30 | neutrophil chemotaxis | CXADR, EDN2, EDN3, FCER1G, IFNG, ITGA1, ITGA9, PDE4B, PDE4D, PIK3CG, PRKCA, S100A8, S100A9, S100A12, CCL20, CCL22, CCL24, CCL25, CX3CL1, XCL2, SYK, VAV1, SLIT2, VAV3 |
589 | GO:0007588 | 0.00 | 5.63 | 10.41 | 20 | 25 | excretion | AQP5, AQP6, AQP7, ATP6V1B1, CHRNB2, CHRNB4, CLCN5, CLCNKA, CLCNKB, GUCA2B, SCNN1B, SCNN1G, SCTR, SLC12A1, TACR2, TRPV1, KCNK5, GRHPR, UNC13B, CLDN16 |
590 | GO:0042311 | 0.00 | 5.63 | 8.33 | 16 | 20 | vasodilation | ADCY6, BBS2, BDKRB2, CRP, ACE, EDNRB, GPX1, HMGCR, ITGA1, KCNJ8, KNG1, P2RX4, P2RY1, P2RY2, SOD2, ATG5 |
591 | GO:0001938 | 0.00 | 5.62 | 16.69 | 32 | 40 | positive regulation of endothelial cell proliferation | ACVRL1, ANG, ARG1, ARNT, BMP4, BMP6, BMPR2, CAV2, CCR3, CYBA, ECM1, EGR3, F3, FGFR3, FLT4, HIF1A, NR4A1, JUN, KDR, PGF, PRKCA, PRKD1, PROX1, CCL24, VEGFA, VEGFB, VIP, WNT2, SCG2, TNFSF12, NRP2, PDCD6 |
592 | GO:0001541 | 0.00 | 5.62 | 12.51 | 24 | 30 | ovarian follicle development | AHR, ANG, BAX, BCL2, BCL2L1, BMP4, CAPN5, CTNNA1, FANCG, FGF7, CENPI, FSHR, ICAM1, INHA, KDR, KIT, KITLG, SOD1, UBE3A, VEGFA, EIF2B4, EIF2B2, EIF2B5, BMP15 |
593 | GO:0034134 | 0.00 | 5.62 | 14.61 | 28 | 35 | toll-like receptor 2 signaling pathway | BTK, CD14, CD36, CHUK, ATF2, CYBA, DUSP4, DUSP7, ELK1, F2RL1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK3, MAPK8, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, TNFAIP3, UBB, UBE2V1, CUL1, IKBKG, RIPK2, RPS6KA5 |
594 | GO:0061180 | 0.00 | 5.61 | 6.25 | 12 | 15 | mammary gland epithelium development | AKT2, CAV3, ETV5, HIF1A, MGMT, PGR, PTCH1, PTHLH, SLC12A2, VDR, WNT2, SLIT2 |
595 | GO:0021766 | 0.00 | 5.61 | 12.52 | 24 | 30 | hippocampus development | ANXA3, BBS2, BBS4, CDK5, CDK6, DCX, EMX2, EPHA5, EZH1, KCNA1, OGDH, PROX1, RELN, PTPRZ1, RARA, SRD5A1, SRF, NR2E1, TP73, TSC1, LRP8, USP9X, CDK5R2, ZEB2 |
596 | GO:0006953 | 0.00 | 5.61 | 8.34 | 16 | 20 | acute-phase response | SERPINA3, AHSG, APCS, ASS1, CRP, FGA, HIF1A, HP, INS, ITIH4, ORM2, REG3A, SAA4, STAT3, STAT5B, CD163 |
597 | GO:0050766 | 0.00 | 5.61 | 10.43 | 20 | 25 | positive regulation of phagocytosis | AHSG, C3, CD36, CYBA, DNM2, F2RL1, FCER1G, GAS6, IL1B, ITGA2, ITGAV, MFGE8, PROS1, RAB27A, RAP1A, RAP1GAP, SFTPD, SLC11A1, TULP1, ABCA7 |
598 | GO:0098801 | 0.00 | 5.61 | 6.25 | 12 | 15 | regulation of renal system process | AGTR2, ANPEP, AVP, AVPR2, COMT, EDNRB, KNG1, OXT, PTGER4, STC1, TAC1, CORIN |
599 | GO:0060428 | 0.02 | 5.61 | 4.17 | 8 | 10 | lung epithelium development | BMP4, CDC42, FGF7, FGFR3, SRSF6, SHH, WNT2, ADAMTSL2 |
600 | GO:0019320 | 0.02 | 5.61 | 4.17 | 8 | 10 | hexose catabolic process | FUT6, FUT8, GALE, GALK1, GLB1, KHK, PGM1, FUT9 |
601 | GO:0006383 | 0.00 | 5.61 | 6.26 | 12 | 15 | transcription from RNA polymerase III promoter | BRCA1, ERBB2, GTF3A, BRF1, SNAPC1, SNAPC2, SNAPC3, SNAPC4, TBP, ZNF76, ZNF143, IVNS1ABP |
602 | GO:0034405 | 0.02 | 5.60 | 4.17 | 8 | 10 | response to fluid shear stress | CA2, F3, HAS2, P2RX4, P2RX7, IFT88, HDAC3, CITED2 |
603 | GO:0046579 | 0.02 | 5.60 | 4.17 | 8 | 10 | positive regulation of Ras protein signal transduction | NRG1, IGF1, ITPKB, KRAS, KITLG, NTRK1, SHOC2, DGKI |
604 | GO:0015721 | 0.00 | 5.60 | 8.35 | 16 | 20 | bile acid and bile salt transport | ALB, AKR1C4, FABP6, ATP8B1, RXRA, SLC10A1, SLC10A2, SLCO1A2, SLC10A3, ABCC3, SLC9A3R1, NR1H4, SLCO1B1, STARD10, SLC27A5, SLCO2B1 |
605 | GO:0045429 | 0.00 | 5.60 | 8.35 | 16 | 20 | positive regulation of nitric oxide biosynthetic process | AGTR2, AKT2, ASS1, CLU, DNM2, ESR1, HSP90AA1, HSP90AB1, ICAM1, IFNG, IL1B, INS, P2RX4, TRPV1, KLF4, KLF2 |
606 | GO:0071827 | 0.00 | 5.60 | 8.35 | 16 | 20 | plasma lipoprotein particle organization | ABCA1, APOA1, APOA4, APOC2, ARF1, SCARB1, CETP, ACSL3, FECH, LCAT, NR1H2, SOAT2, DGAT1, LIPG, ABCG1, ABCA7 |
607 | GO:1902932 | 0.02 | 5.60 | 4.17 | 8 | 10 | positive regulation of alcohol biosynthetic process | BMP6, ACSL3, FGF1, IFNG, IL1B, PRKAA1, SREBF1, ABCG1 |
608 | GO:0001945 | 0.02 | 5.60 | 4.17 | 8 | 10 | lymph vessel development | EFNB2, FLT4, KDR, PTPN14, SYK, VEGFA, VEGFC, PDPN |
609 | GO:0030318 | 0.02 | 5.60 | 4.17 | 8 | 10 | melanocyte differentiation | EDN3, EDNRB, KIT, CITED1, RAB27A, SOX10, TYRP1, USP13 |
610 | GO:0003016 | 0.00 | 5.60 | 6.26 | 12 | 15 | respiratory system process | ADH5, ADORA1, ADRB2, ATP1A2, GAA, GLRA1, GLS, RAB3A, TNNC1, KDM6A, PHOX2B, ECEL1 |
611 | GO:0003197 | 0.00 | 5.60 | 6.26 | 12 | 15 | endocardial cushion development | ACVR1, BMP4, BMPR1A, ERG, FGF8, GATA4, RBPJ, ISL1, SNAI2, SOX9, TWIST1, DCHS1 |
612 | GO:0006706 | 0.00 | 5.60 | 6.26 | 12 | 15 | steroid catabolic process | STS, SCARB1, CYP1A2, CYP3A4, CYP24A1, CYP27B1, SULT2A1, UGT2B4, YWHAH, FGF23, HSD17B6, SNX17 |
613 | GO:0099622 | 0.00 | 5.60 | 6.26 | 12 | 15 | cardiac muscle cell membrane repolarization | CAV3, GJA5, KCNA5, KCNE1, KCNJ2, KCNQ1, SCN4B, SCN5A, SNTA1, WDR1, KCNE2, AKAP9 |
614 | GO:0001946 | 0.02 | 5.59 | 4.17 | 8 | 10 | lymphangiogenesis | ACVR2B, ACVRL1, BMPR2, FLT4, PROX1, PTPN14, VEGFC, PDPN |
615 | GO:0002283 | 0.02 | 5.59 | 4.17 | 8 | 10 | neutrophil activation involved in immune response | ANXA3, FCER1G, PTAFR, STXBP2, STXBP3, SYK, TYROBP, STX11 |
616 | GO:0006297 | 0.02 | 5.59 | 4.17 | 8 | 10 | nucleotide-excision repair, DNA gap filling | RFC1, RFC2, RFC3, RFC4, RFC5, RPA3, RPS27A, UBB |
617 | GO:0006362 | 0.02 | 5.59 | 4.17 | 8 | 10 | transcription elongation from RNA polymerase I promoter | CCNH, ERCC3, ERCC6, TBP, UBTF, TAF1C, TAF1B, TAF1A |
618 | GO:0006363 | 0.02 | 5.59 | 4.17 | 8 | 10 | termination of RNA polymerase I transcription | CCNH, ERCC3, TBP, TTF1, UBTF, TAF1C, TAF1B, TAF1A |
619 | GO:0006828 | 0.02 | 5.59 | 4.17 | 8 | 10 | manganese ion transport | SLC11A2, SLC11A1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, ZP3 |
620 | GO:0007096 | 0.02 | 5.59 | 4.17 | 8 | 10 | regulation of exit from mitosis | BIRC5, CDC14A, CDC23, ZW10, MAD2L1BP, KNTC1, UBE2C, PHB2 |
621 | GO:0007625 | 0.02 | 5.59 | 4.17 | 8 | 10 | grooming behavior | APRT, AVP, CTNS, HPRT1, OXT, PPT1, DDO, NRXN1 |
622 | GO:0009886 | 0.02 | 5.59 | 4.17 | 8 | 10 | post-embryonic morphogenesis | ATRX, BAX, FBN1, EFEMP1, GNAS, HMGN1, KDR, BCL2L11 |
623 | GO:0010893 | 0.02 | 5.59 | 4.17 | 8 | 10 | positive regulation of steroid biosynthetic process | BMP6, FGF1, IFNG, IL1B, PRKAA1, SREBF1, NR1D1, ABCG1 |
624 | GO:0015732 | 0.02 | 5.59 | 4.17 | 8 | 10 | prostaglandin transport | ACSL4, IL1B, OXT, P2RX4, P2RX7, P2RY2, TNFSF11, ABCC4 |
625 | GO:0017187 | 0.02 | 5.59 | 4.17 | 8 | 10 | peptidyl-glutamic acid carboxylation | BGLAP, F7, F10, GAS6, GGCX, PROC, PROS1, PROZ |
626 | GO:0030252 | 0.02 | 5.59 | 4.17 | 8 | 10 | growth hormone secretion | GHRH, GHRHR, GHSR, KISS1, CDK16, RAB1A, LTBP4, ARHGEF7 |
627 | GO:0030539 | 0.02 | 5.59 | 4.17 | 8 | 10 | male genitalia development | BMP6, DHCR24, FGF8, GJB2, HSD17B3, SHH, SOX2, SRD5A1 |
628 | GO:0031274 | 0.02 | 5.59 | 4.17 | 8 | 10 | positive regulation of pseudopodium assembly | APC, CDC42, F2RL1, KIT, CCL21, CDC42EP2, CDC42EP3, CDC42EP1 |
629 | GO:0032332 | 0.02 | 5.59 | 4.17 | 8 | 10 | positive regulation of chondrocyte differentiation | ACVRL1, BMP6, RUNX2, HOXD11, IHH, SMAD3, SOX5, SOX9 |
630 | GO:0032780 | 0.02 | 5.59 | 4.17 | 8 | 10 | negative regulation of ATPase activity | CNN3, LTF, OXA1L, PLN, TNNI3, TNNT2, RGN, ABCA7 |
631 | GO:0033540 | 0.02 | 5.59 | 4.17 | 8 | 10 | fatty acid beta-oxidation using acyl-CoA oxidase | ACAA1, ACOX1, ABCD1, HSD17B4, SCP2, ACOX2, ACOX3, ACOT8 |
632 | GO:0034349 | 0.02 | 5.59 | 4.17 | 8 | 10 | glial cell apoptotic process | BAX, BID, CASP9, GAS6, PRKCA, PRKCI, RB1, TRAF2 |
633 | GO:0035809 | 0.02 | 5.59 | 4.17 | 8 | 10 | regulation of urine volume | ADCY6, ADRB2, AVPR2, EDNRB, HAS2, KNG1, OXT, PTGER4 |
634 | GO:0035886 | 0.02 | 5.59 | 4.17 | 8 | 10 | vascular smooth muscle cell differentiation | CTH, GATA6, HES1, SGCB, SMARCA2, SRF, VEGFA, RAMP2 |
635 | GO:0043011 | 0.02 | 5.59 | 4.17 | 8 | 10 | myeloid dendritic cell differentiation | CAMK4, CD86, CSF2, RBPJ, RELB, TNFSF9, DHRS2, BATF |
636 | GO:0044849 | 0.02 | 5.59 | 4.17 | 8 | 10 | estrous cycle | ADRB2, ANXA1, CLU, ETS1, HAS1, HAS2, PTN, TRPM2 |
637 | GO:0045663 | 0.02 | 5.59 | 4.17 | 8 | 10 | positive regulation of myoblast differentiation | BTG1, FLT3LG, IGFBP3, ILK, MAP3K5, NR2C2, CSRP3, TNFSF14 |
638 | GO:0046827 | 0.02 | 5.59 | 4.17 | 8 | 10 | positive regulation of protein export from nucleus | CAMK4, EMD, GAS6, SFN, IL1B, PPM1A, CAMK1, RAPGEF3 |
639 | GO:0048486 | 0.02 | 5.59 | 4.17 | 8 | 10 | parasympathetic nervous system development | PHOX2A, EGR2, GDNF, HES1, SEMA3F, SIX1, PHOX2B, SEMA3A |
640 | GO:0048643 | 0.02 | 5.59 | 4.17 | 8 | 10 | positive regulation of skeletal muscle tissue development | ADRB2, ARNTL, BCL2, GPC1, HMGCR, PRKAA1, SHH, USP2 |
641 | GO:0055062 | 0.02 | 5.59 | 4.17 | 8 | 10 | phosphate ion homeostasis | FGFR4, ENPP1, SFRP4, SLC34A1, FGF23, XPR1, SLC9A3R1, SLC34A2 |
642 | GO:0060421 | 0.02 | 5.59 | 4.17 | 8 | 10 | positive regulation of heart growth | CCNB1, GATA4, GATA6, NRG1, RBPJ, PROX1, WNT2, AKAP6 |
643 | GO:0060670 | 0.02 | 5.59 | 4.17 | 8 | 10 | branching involved in labyrinthine layer morphogenesis | GRB2, IL10, LLGL2, SPINT1, ST14, FZD5, SOCS3, SPINT2 |
644 | GO:0070633 | 0.02 | 5.59 | 4.17 | 8 | 10 | transepithelial transport | AQP1, CXADR, GPLD1, P2RY4, P2RY6, SLC12A2, SLC23A2, CLDN16 |
645 | GO:0070841 | 0.02 | 5.59 | 4.17 | 8 | 10 | inclusion body assembly | CLU, DNAJB2, PARK2, PSMC5, SORL1, BAG5, SNCAIP, HDAC6 |
646 | GO:0071425 | 0.02 | 5.59 | 4.17 | 8 | 10 | hematopoietic stem cell proliferation | ACE, ETV6, KITLG, EIF2AK2, WNT1, WNT2B, PRG4, ARIH2 |
647 | GO:0072576 | 0.02 | 5.59 | 4.17 | 8 | 10 | liver morphogenesis | HPN, IFNG, MKI67, PROX1, PTN, RPS6KA1, TNFAIP3, CUL3 |
648 | GO:0086012 | 0.02 | 5.59 | 4.17 | 8 | 10 | membrane depolarization during cardiac muscle cell action potential | ATP1A2, CAV3, GJA5, KCNJ2, SCN2B, SCN4B, SCN5A, SLC8A1 |
649 | GO:0016259 | 0.00 | 5.52 | 24.62 | 47 | 59 | selenocysteine metabolic process | FAU, RPL10A, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, RPL14, RPL23, RPL35 |
650 | GO:0070252 | 0.00 | 5.47 | 18.36 | 35 | 44 | actin-mediated cell contraction | ATP1A2, CAV3, DSC2, DSP, EMP2, GATA4, GJA5, JUP, KCNA5, KCNE1, KCNJ2, KCNQ1, PDE4B, PDE4D, PLN, RYR2, SCN2B, SCN4B, SCN5A, SLC9A1, SNTA1, STC1, TMOD1, TNNC2, TNNC1, TNNI2, TNNI3, TNNT1, TNNT2, TPM2, SUMO1, VIL1, VIM, NUP155, KCNE2 |
651 | GO:0006366 | 0.00 | 5.39 | 12.80 | 25 | 32 | transcription from RNA polymerase II promoter | BTF3, DTX1, ERCC6, FLNA, HIVEP2, HLF, SNAPC2, SNAPC3, SNAPC4, TMF1, ZNF141, PIR, RNGTT, TRIM24, TSC22D1, TAF1C, TAF1A, DDX21, TRIP11, TRIP4, TBPL1, CREB5, ZNF516, HSF2BP, ECD |
652 | GO:0034146 | 0.00 | 5.38 | 12.10 | 23 | 29 | toll-like receptor 5 signaling pathway | CHUK, ATF2, DUSP4, DUSP7, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK3, MAPK8, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, TNFAIP3, UBB, UBE2V1, CUL1, IKBKG, RIPK2, RPS6KA5 |
653 | GO:0006614 | 0.00 | 5.37 | 30.05 | 57 | 72 | SRP-dependent cotranslational protein targeting to membrane | FAU, RPL10A, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, SRP9, SRP14, SRP19, SRP68, SSR1, SSR3, RPL14, RPL23, SPCS2, SEC61B, RPL35, SEC63 |
654 | GO:0050796 | 0.00 | 5.35 | 25.78 | 49 | 62 | regulation of insulin secretion | ADRA2C, SLC25A4, ARL2, ARNTL, CACNA1A, CHRM3, CNR1, ENSA, GHSR, GLP1R, GNAS, IFNG, IL1B, INS, ITPR1, ITPR2, ITPR3, KCNA5, KCNJ11, KCNS3, PARK2, PCSK1, PDE3B, PDE4C, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, RAP1A, REST, RFX3, SLC2A2, SLC16A1, SNAP25, SREBF1, STXBP1, ABCC8, IQGAP1, SYT7, STXBP5L, CLOCK, CARTPT, SPCS2, RAPGEF3, RAPGEF4 |
655 | GO:0061333 | 0.00 | 5.31 | 17.95 | 34 | 43 | renal tubule morphogenesis | AGTR2, BCL2, BMP4, CD44, DLG1, EYA1, FGF1, FGF8, FOXD1, GATA3, GDNF, GPC3, HOXD11, HES1, ILK, LAMA5, TACSTD2, CITED1, PAX2, PBX1, PGF, PSPN, PTCH1, SALL1, SHH, SIX1, SOX9, VEGFA, WNT1, WNT11, WNT2B, PAX8, DCHS1, SIX2 |
656 | GO:0032496 | 0.00 | 5.31 | 38.99 | 74 | 94 | response to lipopolysaccharide | ACP5, ADH5, ALAD, ATP4B, CASP8, CASP9, TNFRSF8, CHUK, CNP, CNR1, CNR2, COMT, CPS1, CTSG, CYP1A2, CYP27B1, DCN, DNMT1, EDNRA, F2R, F3, CXCL1, CXCL2, CXCL3, IGF1, IL10RA, IL12RB2, IL13, TNFRSF9, IDO1, JUN, JUNB, JUND, KCNJ8, MGST2, CITED1, NRF1, TNFRSF11B, P2RX7, PAWR, PENK, PF4, PF4V1, EIF2AK2, PROS1, PTGER1, PTGER4, RPS6KA3, S100A8, CXCL6, CXCL5, SELE, SELP, SLC11A1, SLPI, SNCA, SPARC, STAT5B, ABCC8, TAC1, TNFRSF1A, TNFRSF4, SCGB1A1, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, SOCS3, NR1H4, IL18BP, CXCL13, GJB6, PRDX3 |
657 | GO:0001508 | 0.00 | 5.30 | 7.89 | 15 | 19 | action potential | CACNB4, CHRNB4, GLRA1, GNAQ, KCNA5, KCNE1, KCNQ1, NRCAM, SNTA1, CNTNAP1, AKAP7, AKAP6, NUP155, KCNE2, HCN4 |
658 | GO:0006940 | 0.00 | 5.27 | 7.91 | 15 | 19 | regulation of smooth muscle contraction | ADORA1, ADRA2C, ADRB2, ATP1A2, CHRM1, CHRNB4, CNN1, FLT1, GHSR, PRKG1, PTGER4, RGS2, SOD1, TNNI3, CALCRL |
659 | GO:0045576 | 0.00 | 5.26 | 7.92 | 15 | 19 | mast cell activation | RHOH, CNR1, CNR2, KIT, PDPK1, PIK3CG, PTPRE, RAC2, S100A12, S100A13, STXBP2, LAT2, SNAP23, CD84, CPLX2 |
660 | GO:0032024 | 0.00 | 5.26 | 7.92 | 15 | 19 | positive regulation of insulin secretion | ABAT, BLK, CD38, GIP, GLUD1, GLUL, FFAR1, ISL1, PFKFB2, PRKCE, SOX4, TRH, TRPM2, NR0B2, CAPN10 |
661 | GO:0050434 | 0.00 | 5.25 | 7.93 | 15 | 19 | positive regulation of viral transcription | CCNH, CCNT1, CDK9, CHD1, EP300, ERCC3, GTF2F1, HPN, JUN, SMARCA4, SP1, SSRP1, SUPT4H1, CTDP1, SUPT16H |
662 | GO:0018130 | 0.01 | 5.25 | 5.06 | 10 | 13 | heterocycle biosynthetic process | CPS1, DDC, IDO1, OAT, PYCR1, ALDH18A1, QDPR, PDXK, ALDH4A1, PRG3 |
663 | GO:0001667 | 0.00 | 5.24 | 11.56 | 22 | 28 | ameboidal-type cell migration | ACVR1B, ARHGAP4, ARHGDIB, C1QBP, FGF8, HAS1, ILK, ITGA4, ITGB4, DDR2, RAC1, SDC4, SLC8A1, T, TNS1, WNT11, ARHGEF7, SGPL1, CER1, BAG4, WASF2, CAP1 |
664 | GO:0032368 | 0.00 | 5.23 | 13.75 | 26 | 33 | regulation of lipid transport | ABCA1, ABCA2, APOA1, APOA4, BMP6, TSPO, CETP, GALR1, GDF9, IL1B, NTSR1, OXT, P2RX4, P2RX7, P2RY2, PARK2, PTCH1, SCP2, SYK, TAC1, TMF1, TNFSF11, LIPG, ABCG1, ABCA7, ATP8A1 |
665 | GO:0046661 | 0.00 | 5.22 | 31.27 | 59 | 75 | male sex differentiation | ACVR2A, NR0B1, AMHR2, ATRX, BAX, CCND1, BCL2, BCL2L1, BIK, BMPR1A, BOK, COL9A3, CTNNA1, CTSV, ERCC1, ESR1, FANCA, FGF9, FSHR, NR5A1, GATA3, GATA4, GATA6, HSD17B10, HMGCS1, HSD17B4, ICAM1, ING2, INHA, INSL3, KIT, MEA1, KITLG, NTRK1, PRKACG, RAB13, RARA, ARID4A, RRM1, SDC1, SOX9, SRY, STAR, STAT5B, TMF1, UBB, WNT2B, CSDE1, UTF1, AKR1C3, ADAM15, SGPL1, EIF2S2, BCL2L11, AKAP9, FSTL3, CITED2, SEMA3A, PRDX4 |
666 | GO:0051384 | 0.00 | 5.22 | 23.23 | 44 | 56 | response to glucocorticoid | ACADS, AGXT, ALAD, ALDH3A1, ALDOB, ANXA3, AREG, BAD, BCHE, BCL2, BGLAP, BMP4, BMP6, C3, CALCR, CDO1, CTSV, DUSP1, GHRHR, GOT1, HIF1A, IGF1, IGFBP2, IL1RN, IL10, KRAS, LCAT, OXT, PAM, RXRA, S100B, SDC1, SHC1, SLC9A3, SLIT3, SPARC, TAT, TYMS, UCN, SCGB1A1, ADAM9, SOCS3, SLIT2, PTPRU |
667 | GO:0046209 | 0.00 | 5.21 | 13.77 | 26 | 33 | nitric oxide metabolic process | ACP5, AGTR2, AKT2, ARG2, ASS1, TSPO, CALM3, CLU, CPS1, DHFR, DNM2, ESR1, HSP90AA1, HSP90AB1, ICAM1, IFNG, IGF1, IL1B, IL10, INS, P2RX4, PTGIS, TRPV1, RGN, KLF4, KLF2 |
668 | GO:0046883 | 0.00 | 5.20 | 26.94 | 51 | 65 | regulation of hormone secretion | SLC25A4, ANXA1, ARL2, ARNTL, CACNA1A, CACNA1E, CHRM3, CNR1, EFNA5, ENSA, EPHA5, GDF9, GLP1R, GNAS, FFAR3, FOXA2, HTR2C, IFNG, ITPR1, ITPR2, ITPR3, KCNA5, KCNS3, PCSK1, CDK16, PDE3B, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, RAP1A, RFX3, SLC2A2, SLC16A1, SNAP25, STXBP1, PAX8, IQGAP1, SYT7, HMGN3, NRXN1, NR1D1, CLOCK, SPCS2, NR1H4, RAPGEF3, RAPGEF4 |
669 | GO:0001505 | 0.01 | 5.19 | 5.81 | 11 | 14 | regulation of neurotransmitter levels | ACHE, ALDH2, ALDH9A1, DAGLA, COMT, GLUL, KCNJ10, PAH, PDE1B, SLC6A4, SLC22A3 |
670 | GO:0060191 | 0.00 | 5.18 | 29.21 | 55 | 70 | regulation of lipase activity | ABL2, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADCYAP1R1, ADRBK1, ANG, ANXA1, APOA1, APOA4, APOC2, APOH, ARF4, ARHGAP6, ARL1, AVPR1B, BICD1, CALM3, CAMK4, LPAR1, EDNRA, ESR1, FGFR3, FLT1, GNA15, GNAQ, ITPR1, ITPR2, ITPR3, KIT, NTRK1, PDE1B, PDPK1, PPT1, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCE, PRKCG, PRKCZ, PTAFR, RGS2, SORT1, SELE, SNCA, NR1H2, S1PR4, GPR55 |
671 | GO:0008585 | 0.01 | 5.17 | 5.82 | 11 | 14 | female gonad development | AMHR2, BRCA2, COL9A3, FANCA, IDH1, PGR, SLIT3, UBB, NRIP1, SLIT2, ADAMTS1 |
672 | GO:0002690 | 0.00 | 5.16 | 17.53 | 33 | 42 | positive regulation of leukocyte chemotaxis | ADAM10, C1QBP, CD74, CCR1, CMKLR1, EDN2, EDN3, EDNRA, F2RL1, F7, GAS6, CXCL1, CXCL2, CXCL3, IL1B, SERPINE1, PF4, PF4V1, RAC1, RAC2, CCL21, CXCL6, CXCL5, XCL1, CX3CL1, VEGFA, VEGFB, VEGFC, TNFSF14, TNFSF18, CXCL14, CREB3, CXCL13 |
673 | GO:0006833 | 0.00 | 5.14 | 11.69 | 22 | 28 | water transport | ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, AQP1, AQP5, AQP6, AQP7, AVP, AVPR2, GNAS, HAS2, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, UPK3A, RAB11A |
674 | GO:0034166 | 0.00 | 5.14 | 11.69 | 22 | 28 | toll-like receptor 10 signaling pathway | CHUK, ATF2, DUSP4, DUSP7, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK3, MAPK8, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, UBB, UBE2V1, CUL1, IKBKG, RIPK2, RPS6KA5 |
675 | GO:0010558 | 0.00 | 5.14 | 7.31 | 14 | 18 | negative regulation of macromolecule biosynthetic process | AP2A1, APBB1, CLTC, GHSR, IL10, INHA, ITGAV, PF4, PGGT1B, PTGER4, RAP1A, SFTPD, PRG4, RAPGEF3 |
676 | GO:0070266 | 0.01 | 5.14 | 5.84 | 11 | 14 | necroptotic process | CYLD, PYGL, RPS27A, TRAF2, UBB, TRADD, RIPK1, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR |
677 | GO:0001958 | 0.01 | 5.13 | 5.84 | 11 | 14 | endochondral ossification | BMP4, BMP6, RUNX2, COL1A1, COL2A1, COL10A1, DLX5, FGFR3, GNAS, INPPL1, PTHLH |
678 | GO:0007274 | 0.01 | 5.13 | 5.84 | 11 | 14 | neuromuscular synaptic transmission | CACNA1A, CHRM1, CHRNB2, CHRNB4, DTNA, EGR3, ETV5, NTF3, P2RX3, RAB3A, STXBP1 |
679 | GO:0009110 | 0.01 | 5.13 | 5.84 | 11 | 14 | vitamin biosynthetic process | CYP3A4, CYP27B1, GFI1, IFNG, IL1B, SNAI2, SNAI1, VDR, RGN, GSTO1, AKR1A1 |
680 | GO:0010922 | 0.01 | 5.13 | 5.84 | 11 | 14 | positive regulation of phosphatase activity | AGTR2, CALM3, GPLD1, IFNG, ITGA1, ITGA2, SMAD3, PPP1R12A, PAWR, RGN, AKAP6 |
681 | GO:0021871 | 0.01 | 5.13 | 5.84 | 11 | 14 | forebrain regionalization | BMP4, EMX1, EMX2, FGF8, TRA2B, SHH, SIX3, NR2F1, WNT1, WNT2B, EOMES |
682 | GO:0032925 | 0.01 | 5.13 | 5.84 | 11 | 14 | regulation of activin receptor signaling pathway | ACVR1, ACVR1B, ACVR2A, ACVR2B, FGF9, SMAD7, MEN1, SHH, ZIC2, CER1, FSTL3 |
683 | GO:0033006 | 0.01 | 5.13 | 5.84 | 11 | 14 | regulation of mast cell activation involved in immune response | FCER1A, FCER1G, FGR, IL13, PDPK1, RAC2, STXBP2, SYK, VAMP8, CD84, GAB2 |
684 | GO:0046697 | 0.01 | 5.13 | 5.84 | 11 | 14 | decidualization | BSG, CTSV, CYP27B1, ESR1, GHSR, GJB2, JUNB, MEN1, PTGIS, STC1, VDR |
685 | GO:0048566 | 0.01 | 5.13 | 5.84 | 11 | 14 | embryonic digestive tract development | ADA, FGF9, GATA4, HLX, IHH, PCSK5, RARB, SALL1, SOX11, ALDH1A2, SIX2 |
686 | GO:0051953 | 0.01 | 5.13 | 5.84 | 11 | 14 | negative regulation of amine transport | ABAT, ADORA1, ADRA2C, AGTR2, CNR1, IL1B, P2RY1, PTGS1, SNCA, TRH, HRH3 |
687 | GO:2001267 | 0.01 | 5.13 | 5.84 | 11 | 14 | regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | BAX, CASP8, CD14, SMAD3, TRAF2, TRADD, RIPK1, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR |
688 | GO:0030810 | 0.00 | 5.12 | 21.28 | 40 | 51 | positive regulation of nucleotide biosynthetic process | ABCA1, ADCY7, ADCYAP1R1, ADORA2A, ADRB2, AVP, AVPR2, CALCR, CALM3, EDNRA, FSHR, GCG, GHRH, GHRHR, GLP1R, GNAL, GNAS, GUCA1A, GUCA1B, GUCA2A, GUCA2B, INSL3, NTRK1, NTRK2, P2RY11, PRKCA, PTGER4, PTHLH, RAF1, RCVRN, STAT3, UCN, VIP, VIPR2, WFS1, GUCA1C, CALCRL, RAMP2, CAP2, CAP1 |
689 | GO:0019222 | 0.03 | 5.11 | 2.97 | 6 | 8 | regulation of metabolic process | HK2, PRCP, STK17A, SMG7, FBLN5, TUSC2 |
690 | GO:0097305 | 0.03 | 5.08 | 3.67 | 7 | 9 | response to alcohol | ACP5, APC, CDKN2D, CCR5, SLIT3, STC1, SLIT2 |
691 | GO:0001659 | 0.00 | 5.05 | 9.60 | 18 | 23 | temperature homeostasis | ABAT, ACADL, ACADVL, ADORA1, ADRB2, CNR1, DBH, EDN2, EDNRB, GPX1, IL1A, IL1B, IL1RN, NTSR1, STAT3, TRPV1, TNFSF11, NR1D1 |
692 | GO:0043525 | 0.00 | 5.05 | 9.60 | 18 | 23 | positive regulation of neuron apoptotic process | ATF4, ATM, BAX, CASP9, CDC42, CDK5, ATF2, EPHA7, FGFR3, ITGA1, JUN, MAP3K11, PARK2, PAWR, SRPK2, AIFM1, HDAC4, BCL2L11 |
693 | GO:0044259 | 0.00 | 5.04 | 26.71 | 50 | 64 | multicellular organismal macromolecule metabolic process | ADAM10, ARG1, BMP4, SERPINH1, COL1A1, COL2A1, COL3A1, COL4A3, COL4A4, COL4A5, COL4A6, COL5A1, COL5A2, COL6A2, COL6A3, COL9A1, COL9A3, COL10A1, COL11A1, COL12A1, COL16A1, COL17A1, COL19A1, CTGF, CTSD, CTSK, CTSS, ACE, ENPEP, F2R, FAP, HIF1A, IHH, ITGA2, ITGB1, CIITA, P2RX7, PEPD, KLK6, RAP1A, UCN, COL14A1, AKR1C3, SERPINB7, ADAM15, ADAM9, ADAMTS3, ADAMTS2, TRAM2, RAPGEF3 |
694 | GO:1901617 | 0.03 | 4.98 | 3.72 | 7 | 9 | organic hydroxy compound biosynthetic process | ACADM, ALDH9A1, ALOX12, LDHC, SHMT1, BBOX1, PDXK |
695 | GO:0042063 | 0.03 | 4.97 | 3.72 | 7 | 9 | gliogenesis | ANXA1, AREG, ASCL2, EEF2, PENK, PTN, RNF10 |
696 | GO:0045137 | 0.00 | 4.96 | 50.50 | 94 | 121 | development of primary sexual characteristics | ACVR1B, ACVR2A, ADCYAP1R1, NR0B1, AHR, AMHR2, ANG, ATRX, BAX, CCND1, BCL2, BCL2L1, BIK, BMP4, BOK, BRCA2, CAPN5, CCNE1, COL9A3, CTNNA1, CTSV, ERCC1, EREG, ESR1, FANCA, FANCG, FGF7, FGF8, FGF9, CENPI, FSHR, NR5A1, GATA3, GATA4, GATA6, GDF9, HSD17B10, HMGCS1, HSD17B4, ICAM1, IDH1, ING2, INHA, INSL3, KDR, KIT, MEA1, KITLG, NTRK1, PGR, PRKACG, PTGER4, PTPRN, RAB13, RARA, ARID4A, RRM1, SALL1, SDC1, SLIT3, SOD1, SOX9, SRD5A1, SRY, STAR, STAT5B, TMF1, TSPY1, UBB, UBE3A, VEGFA, WNT2B, ZP3, CSDE1, NRIP1, FZD4, UTF1, AKR1C3, ADAM15, SGPL1, EIF2B4, EIF2B2, EIF2B5, EIF2S2, BMP15, SLIT2, ADAMTS1, BCL2L11, AKAP9, IRX5, FSTL3, CITED2, SEMA3A, PRDX4 |
697 | GO:0048771 | 0.00 | 4.95 | 11.22 | 21 | 27 | tissue remodeling | ACP5, ADRB2, ANXA1, TPP1, CSPG4, CTSK, EPHA2, F2R, GJA5, HIF1A, IHH, IL1A, LIPA, PTH1R, RAC1, RAC2, SLC34A1, RAB7A, GPR55, RAB3D, RASSF2 |
698 | GO:0071248 | 0.00 | 4.94 | 11.22 | 21 | 27 | cellular response to metal ion | AQP1, ATF4, BMP6, BNIP3, TSPO, CCNB1, CD86, CYP11B1, EIF2S1, GLRA1, GLRA2, HIF1A, KCNA1, KCNK3, PARK2, SERPINF1, SLC34A1, SNCA, BECN1, EIF2AK3, FSTL3 |
699 | GO:0030879 | 0.03 | 4.94 | 3.74 | 7 | 9 | mammary gland development | ARHGAP5, NRG1, IGF1, IGF1R, ITGA2, SOX9, BCL2L11 |
700 | GO:0002224 | 0.03 | 4.93 | 3.74 | 7 | 9 | toll-like receptor signaling pathway | CTSK, CTSS, GFI1, PDPK1, TYRO3, BCL10, CNPY3 |
701 | GO:0006977 | 0.00 | 4.92 | 18.78 | 35 | 45 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | ATM, CDKN1A, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SOX4, UBB, CRADD, PSMF1, PSMD6, PSME3 |
702 | GO:1902400 | 0.00 | 4.92 | 18.78 | 35 | 45 | intracellular signal transduction involved in G1 DNA damage checkpoint | ATM, CDKN1A, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SOX4, UBB, CRADD, PSMF1, PSMD6, PSME3 |
703 | GO:0051952 | 0.00 | 4.92 | 11.25 | 21 | 27 | regulation of amine transport | ADRBK1, ARG1, ATP1A2, AVP, CACNA1A, CCK, CHRNB2, GDNF, FFAR3, KCNA2, SEPT2, NTSR1, OXT, P2RX7, PARK2, PCP4, RAB3B, SLC18A1, TACR2, CARTPT, SLC38A3 |
704 | GO:0060333 | 0.00 | 4.92 | 11.25 | 21 | 27 | interferon-gamma-mediated signaling pathway | CAMK2A, CAMK2G, CD44, FCGR1B, HCK, HLA-DQA1, ICAM1, IRF1, IRF2, IRF5, CIITA, OAS1, OAS2, OAS3, PTAFR, SP100, TRIM25, OASL, TRIM22, IFI30, TRIM38 |
705 | GO:0032870 | 0.00 | 4.92 | 17.34 | 33 | 43 | cellular response to hormone stimulus | ASIP, ASNS, AVPR1B, AVPR2, BBS2, BBS4, AKR1C4, DUSP1, ACSL1, FSHR, GATA4, GATA6, HMGCS1, TNC, IGFBP2, JUN, JUNB, JUND, P2RY4, P2RY6, PGF, PRCP, PRKCE, PTGDR, PTGER4, SLC5A5, SLIT3, TRH, TNFSF4, PAX8, LATS1, SLIT2, RAMP2 |
706 | GO:0032200 | 0.03 | 4.92 | 3.75 | 7 | 9 | telomere organization | H3F3B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H3F |
707 | GO:1902930 | 0.03 | 4.92 | 3.75 | 7 | 9 | regulation of alcohol biosynthetic process | CYP27B1, GFI1, REST, SNAI2, SNAI1, VDR, AKR1C3 |
708 | GO:0010524 | 0.03 | 4.91 | 3.75 | 7 | 9 | positive regulation of calcium ion transport into cytosol | ADCYAP1R1, BMP4, CD4, P2RX3, P2RX4, P2RX7, TRPC3 |
709 | GO:0019731 | 0.00 | 4.91 | 11.27 | 21 | 27 | antibacterial humoral response | ANG, KLK3, DEFA1, DMBT1, FAU, FGA, LTF, PGC, KLK7, RNASE3, RPL39, SEMG1, SLPI, TAC1, VIP, HIST1H2BG, HIST1H2BF, HIST2H2BE, HIST1H2BJ, SPON2, SPINK5 |
710 | GO:0017158 | 0.03 | 4.91 | 3.75 | 7 | 9 | regulation of calcium ion-dependent exocytosis | CACNA1A, B4GALT1, REST, SPINK1, STXBP3, SYT4, DOC2A |
711 | GO:0010611 | 0.03 | 4.90 | 3.75 | 7 | 9 | regulation of cardiac muscle hypertrophy | CAV3, P2RX4, RGS2, COL14A1, AKAP1, CTDP1, AKAP13 |
712 | GO:0071715 | 0.03 | 4.90 | 3.75 | 7 | 9 | icosanoid transport | AGTR2, ANXA1, BDKRB2, ACE, NTSR1, SYK, CYP4F2 |
713 | GO:0002251 | 0.00 | 4.90 | 7.51 | 14 | 18 | organ or tissue specific immune response | APOA4, DEFA1, FAU, FFAR3, LTF, PIGR, RNASE3, RPL39, XCL1, HIST1H2BG, HIST1H2BF, HIST2H2BE, TNFSF13, HIST1H2BJ |
714 | GO:0010165 | 0.00 | 4.90 | 7.51 | 14 | 18 | response to X-ray | ANXA1, CCND1, BRCA2, CDKN1A, DNM2, ERCC1, ERCC6, GATA3, HIF1A, RAD51, TP73, XRCC2, XRCC4, TP63 |
715 | GO:0033081 | 0.00 | 4.90 | 7.51 | 14 | 18 | regulation of T cell differentiation in thymus | ADA, BMP4, CAMK4, CDKN2A, EGR3, ERBB2, IHH, IL1B, SHH, SOD1, SOS1, SOS2, FOXN1, VNN1 |
716 | GO:1902622 | 0.00 | 4.90 | 7.51 | 14 | 18 | regulation of neutrophil migration | C1QBP, CD74, EDNRA, CXCL1, CXCL2, CXCL3, IL1B, PAWR, PTGER4, RAC1, RAC2, CCL21, XCL1, SLIT2 |
717 | GO:0010894 | 0.03 | 4.90 | 3.75 | 7 | 9 | negative regulation of steroid biosynthetic process | INSIG1, PROX1, REST, SOD1, NR1H4, ERLIN1, ERLIN2 |
718 | GO:0086019 | 0.03 | 4.90 | 3.75 | 7 | 9 | cell-cell signaling involved in cardiac conduction | CXADR, KCNA5, KCNQ1, SCN4B, SCN10A, NUP155, HCN4 |
719 | GO:0001660 | 0.03 | 4.89 | 3.76 | 7 | 9 | fever generation | CNR1, EDNRB, IL1A, IL1B, IL1RN, TRPV1, TNFSF11 |
720 | GO:0002070 | 0.03 | 4.89 | 3.76 | 7 | 9 | epithelial cell maturation | CDKN1A, HIF1A, PGR, RFX3, SIX3, TYMS, FEM1B |
721 | GO:0002183 | 0.03 | 4.89 | 3.76 | 7 | 9 | cytoplasmic translational initiation | EIF4EBP1, RBM4, DENR, EIF3A, EIF3D, CDC123, EIF3M |
722 | GO:0002922 | 0.03 | 4.89 | 3.76 | 7 | 9 | positive regulation of humoral immune response | C3, FCER2, HPX, PGC, PHB, KLK7, ZP3 |
723 | GO:0003215 | 0.03 | 4.89 | 3.76 | 7 | 9 | cardiac right ventricle morphogenesis | GATA3, GATA4, ISL1, SMARCD3, SOX4, HAND1, HAND2 |
724 | GO:0009650 | 0.03 | 4.89 | 3.76 | 7 | 9 | UV protection | CAT, ERCC1, ERCC3, ERCC4, ERCC5, FEN1, GPX1 |
725 | GO:0010042 | 0.03 | 4.89 | 3.76 | 7 | 9 | response to manganese ion | ARG1, ATF4, TSPO, EIF2S1, PARK2, ADAM9, EIF2AK3 |
726 | GO:0010447 | 0.03 | 4.89 | 3.76 | 7 | 9 | response to acidic pH | CTSS, GIP, PCK1, SERPINF1, SLC9A1, RAB11B, SLC38A3 |
727 | GO:0010664 | 0.03 | 4.89 | 3.76 | 7 | 9 | negative regulation of striated muscle cell apoptotic process | NRG1, HMGCR, ILK, PDPK1, HAND2, BAG3, RAPGEF3 |
728 | GO:0010738 | 0.03 | 4.89 | 3.76 | 7 | 9 | regulation of protein kinase A signaling | FSHR, PDE4A, AKAP4, AIP, AKAP6, PDE10A, AKAP11 |
729 | GO:0015671 | 0.03 | 4.89 | 3.76 | 7 | 9 | oxygen transport | HBA1, HBA2, HBM, HBD, HBG1, HBG2, HBQ1 |
730 | GO:0030728 | 0.03 | 4.89 | 3.76 | 7 | 9 | ovulation | EREG, HPGD, IL1B, IL1R1, PGR, NRIP1, ADAMTS1 |
731 | GO:0032486 | 0.03 | 4.89 | 3.76 | 7 | 9 | Rap protein signal transduction | RAPGEF1, RAP1A, RAP2A, RAP2B, RDX, RAPGEF2, RAPGEF3 |
732 | GO:0033605 | 0.03 | 4.89 | 3.76 | 7 | 9 | positive regulation of catecholamine secretion | ADRBK1, CHRNB2, GDNF, OXT, PCP4, SLC18A1, CARTPT |
733 | GO:0033700 | 0.03 | 4.89 | 3.76 | 7 | 9 | phospholipid efflux | ABCA1, ABCA2, APOA1, APOA4, APOC2, ABCG1, ABCA7 |
734 | GO:0036499 | 0.03 | 4.89 | 3.76 | 7 | 9 | PERK-mediated unfolded protein response | ASNS, ATF3, ATF4, EIF2S1, PTPN1, EIF2AK3, AGR2 |
735 | GO:0044321 | 0.03 | 4.89 | 3.76 | 7 | 9 | response to leptin | BBS2, BBS4, CCND1, STAR, STAT3, FGF23, NR1D1 |
736 | GO:0045651 | 0.03 | 4.89 | 3.76 | 7 | 9 | positive regulation of macrophage differentiation | CASP8, HCLS1, PF4, PRKCA, RB1, RIPK1, TRIB1 |
737 | GO:0046037 | 0.03 | 4.89 | 3.76 | 7 | 9 | GMP metabolic process | DLG1, DLG2, DLG3, GUK1, HPRT1, IMPDH1, IMPDH2 |
738 | GO:0046385 | 0.03 | 4.89 | 3.76 | 7 | 9 | deoxyribose phosphate biosynthetic process | ADK, DTYMK, DUT, GUK1, SHMT1, TYMS, TBPL1 |
739 | GO:0048169 | 0.03 | 4.89 | 3.76 | 7 | 9 | regulation of long-term neuronal synaptic plasticity | KCNJ10, KIT, KRAS, RAB8A, SNCA, SYP, RAB11A |
740 | GO:0051131 | 0.03 | 4.89 | 3.76 | 7 | 9 | chaperone-mediated protein complex assembly | APCS, CLU, HSPA4, HSP90AA1, HDAC6, CCT2, CCT6B |
741 | GO:0051957 | 0.03 | 4.89 | 3.76 | 7 | 9 | positive regulation of amino acid transport | ABAT, AVP, CCK, NTSR1, P2RX7, TRH, SLC38A3 |
742 | GO:0055098 | 0.03 | 4.89 | 3.76 | 7 | 9 | response to low-density lipoprotein particle | ABCA1, CD9, CD36, F3, FCER1G, ITGB1, SYK |
743 | GO:0060218 | 0.03 | 4.89 | 3.76 | 7 | 9 | hematopoietic stem cell differentiation | CDK6, CHD2, ACE, EIF2AK2, SRF, TAL1, BATF |
744 | GO:0060259 | 0.03 | 4.89 | 3.76 | 7 | 9 | regulation of feeding behavior | CNR1, INS, STAT3, TACR3, TRH, UCN, IFT88 |
745 | GO:0060438 | 0.03 | 4.89 | 3.76 | 7 | 9 | trachea development | BMP4, EDA, MAPK3, RARA, SHH, SOX9, SRF |
746 | GO:0060445 | 0.03 | 4.89 | 3.76 | 7 | 9 | branching involved in salivary gland morphogenesis | FGF7, FGF8, HGF, LAMA5, SHH, SNAI2, SEMA3A |
747 | GO:0060456 | 0.03 | 4.89 | 3.76 | 7 | 9 | positive regulation of digestive system process | AQP1, OXT, PAWR, SLC22A5, TAC1, NR1H2, TRPV1 |
748 | GO:0060572 | 0.03 | 4.89 | 3.76 | 7 | 9 | morphogenesis of an epithelial bud | BMP4, HHEX, PTHLH, SHH, WNT2, WNT2B, TP63 |
749 | GO:0060788 | 0.03 | 4.89 | 3.76 | 7 | 9 | ectodermal placode formation | CDC42, EDA, GNAS, PROX1, SIX1, SOX2, NRG3 |
750 | GO:0070723 | 0.03 | 4.89 | 3.76 | 7 | 9 | response to cholesterol | ABCA1, ACP5, CCR5, GPLD1, HMGCS1, PTCH1, LRP8 |
751 | GO:0071696 | 0.03 | 4.89 | 3.76 | 7 | 9 | ectodermal placode development | CDC42, EDA, GNAS, PROX1, SIX1, SOX2, NRG3 |
752 | GO:0072189 | 0.03 | 4.89 | 3.76 | 7 | 9 | ureter development | BMP4, GATA3, PAX2, SHH, SIX1, SOX9, ALDH1A2 |
753 | GO:0072283 | 0.03 | 4.89 | 3.76 | 7 | 9 | metanephric renal vesicle morphogenesis | BMP4, GDNF, CITED1, PAX2, SALL1, PAX8, SIX2 |
754 | GO:0072574 | 0.03 | 4.89 | 3.76 | 7 | 9 | hepatocyte proliferation | HPN, IFNG, MKI67, PROX1, PTN, RPS6KA1, TNFAIP3 |
755 | GO:0097484 | 0.03 | 4.89 | 3.76 | 7 | 9 | dendrite extension | PARK2, STK11, SYT1, SYT4, CPNE6, RIMS2, SLC9A6 |
756 | GO:0098901 | 0.03 | 4.89 | 3.76 | 7 | 9 | regulation of cardiac muscle cell action potential | CAV3, CXADR, DSC2, DSP, GJA5, JUP, RYR2 |
757 | GO:1900116 | 0.03 | 4.89 | 3.76 | 7 | 9 | extracellular negative regulation of signal transduction | AGTR2, FBN1, LRPAP1, LTBP1, CD46, CER1, IL18BP |
758 | GO:1900409 | 0.03 | 4.89 | 3.76 | 7 | 9 | positive regulation of cellular response to oxidative stress | PARK2, SFPQ, SNCA, SOD1, TRPM2, RGN, HDAC6 |
759 | GO:2000251 | 0.03 | 4.89 | 3.76 | 7 | 9 | positive regulation of actin cytoskeleton reorganization | CDK5, HCK, HCLS1, NTF3, NTRK3, RAPGEF3, BAIAP2 |
760 | GO:0002223 | 0.00 | 4.87 | 33.39 | 62 | 80 | stimulatory C-type lectin receptor signaling pathway | CALM3, CASP8, CHUK, EP300, FCER1G, FYN, ICAM2, IL1B, ITPR1, ITPR2, ITPR3, KRAS, NRAS, PDPK1, PPP3R1, PRKACA, PRKACB, PRKACG, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RAF1, RELB, RPS27A, SKP1, SYK, UBB, UBE2D1, UBE2D2, UBE2V1, CUL1, IKBKG, BCL10, UBA3, RPS6KA5, PSMF1, PSMD6, PSME3, MALT1 |
761 | GO:0008015 | 0.00 | 4.87 | 10.60 | 20 | 26 | blood circulation | ADORA2A, ANGPT1, SERPING1, COL4A3, CYB5R3, RCAN1, E2F4, ELN, EPB41, FLI1, ARHGAP35, GUCY1B3, MEOX2, OLR1, PDE3A, PTPRJ, XCL2, TACR2, VEGFA, SLIT2 |
762 | GO:0045937 | 0.00 | 4.86 | 15.21 | 29 | 38 | positive regulation of phosphate metabolic process | ABCA1, ADORA2A, APOC2, AVPR2, CALCR, ACSL3, GHRH, GHRHR, GLP1R, GNAL, GNAS, GUCA1A, GUCA1B, GUCA2A, GUCA2B, INSL3, P2RY11, PF4, PTHLH, RCVRN, STAT3, VIP, VIPR2, WFS1, GUCA1C, CALCRL, RAMP2, CAP2, CAP1 |
763 | GO:0042493 | 0.00 | 4.85 | 83.26 | 154 | 200 | response to drug | ABAT, ABCA1, ABCA2, ADA, ADCY1, ADCYAP1R1, ADD3, PARP4, AK4, ALAD, ALDH3A1, ALDOB, ANXA1, APC, APOA1, AQP1, ARG1, ASS1, ATP4A, ATR, BAD, BAX, BCHE, CCND1, BCL2, BDKRB2, BGLAP, TSPO, CAT, CCNB1, CCNE1, CD86, CD38, CDH1, CDH3, CDK4, CDK9, CDKN1A, CENPF, CHUK, COL1A1, COMT, CPS1, CYBA, DAD1, DHODH, DNMT1, DNMT3A, DNMT3B, EEF2, EMX1, EMX2, ACSL1, FECH, FGF8, FYN, GABRA4, GAD1, GAD2, GATA3, GATA4, GATA6, GIP, GK, GNAS, GRIN2A, HADHA, HMBS, HMGCS1, HMGCS2, HTR2C, ICAM1, IFNG, IGF2, IGFBP2, IL10, ITGA2, ITGA3, ITGB1, JUN, JUNB, JUND, KCNJ11, KCNK3, LDHA, MGMT, NTRK1, NTS, OGG1, TNFRSF11B, OTC, OXCT1, P2RX7, PAM, PDE3A, ATP8B1, PGF, ABCB1, PRKAR2B, PTCH1, PTGER4, PTN, PTPRM, ABCD3, RAD51, RPN2, SLC6A4, SLC6A11, SLC8A1, SLC9A1, SLC15A2, SLC34A1, SLC18A1, SLC22A1, SLC22A3, SLC22A2, SLC22A5, SMPD1, SNCA, SOD1, SORD, SRD5A1, SREBF1, SRP14, SRP19, SRP68, STAR, STAT3, ABCC8, TOP1, TP73, TYMS, SCGB1A1, UQCRFS1, VEGFB, VEGFC, XPC, LRP8, FOSL1, BCAR3, BECN1, GGH, SOCS3, ABCG2, ATG5, HDAC4, COQ7, CCNO, VAV3, AGPAT2, TXNIP, EBP, PAPD7, SCN11A |
764 | GO:0014823 | 0.00 | 4.81 | 12.94 | 24 | 31 | response to activity | ADSL, AKT2, ALAD, ANGPT2, BGLAP, BMP6, CAT, DNMT1, DNMT3B, HIF1A, IGF1, IL10, ITGA2, ITGB1, NTRK1, OXCT1, OXT, PCK1, PRKAA1, PTN, RYR2, SRD5A1, STAR, UQCRC1 |
765 | GO:0060048 | 0.00 | 4.80 | 9.14 | 17 | 22 | cardiac muscle contraction | ADRBK1, GAA, KCNA5, KCNE1, SCN2B, SCN4B, SRSF1, SNTA1, TAZ, TNNC1, TNNI2, TNNI3, TNNT2, VEGFB, CSRP3, NUP155, KCNE2 |
766 | GO:1901362 | 0.01 | 4.79 | 4.63 | 9 | 12 | organic cyclic compound biosynthetic process | CPS1, IDO1, OAT, PYCR1, ALDH18A1, QDPR, PDXK, ALDH4A1, PRG3 |
767 | GO:0072088 | 0.00 | 4.78 | 18.36 | 34 | 44 | nephron epithelium morphogenesis | AGTR2, BCL2, BMP4, CD44, DLG1, EYA1, FGF1, FGF8, FOXD1, GATA3, GDNF, GPC3, HOXD11, HES1, ILK, LAMA5, TACSTD2, CITED1, PAX2, PBX1, PGF, PSPN, PTCH1, SALL1, SHH, SIX1, SOX9, VEGFA, WNT1, WNT11, WNT2B, PAX8, DCHS1, SIX2 |
768 | GO:0006970 | 0.00 | 4.77 | 9.17 | 17 | 22 | response to osmotic stress | AKT2, AVP, BAX, ATF2, TSC22D3, HIF1A, HSP90AB1, ITGA2, NTS, OXT, PCP4, PDPK1, RAC1, SORD, TACR3, MAP7, TSC22D2 |
769 | GO:0098657 | 0.00 | 4.77 | 9.18 | 17 | 22 | import into cell | GDNF, GFAP, GLUL, GPM6B, ITGA4, KCNJ10, NTSR1, PARK2, PAWR, RAB3B, SLC6A4, SLC8A3, SLC18A1, SLC22A3, SNAP25, SNCA, PICALM |
770 | GO:0003254 | 0.00 | 4.76 | 9.18 | 17 | 22 | regulation of membrane depolarization | ALOX12, BCL2, TSPO, CAV3, CCK, DCN, IFI6, GJA5, KDR, SMAD7, NTSR1, P2RX7, PTPN3, SCN2B, SCN5A, SCN10A, HCN4 |
771 | GO:0007595 | 0.00 | 4.76 | 9.18 | 17 | 22 | lactation | APRT, ATP2B2, ATP7B, CCND1, CDO1, CHUK, DHODH, SLC29A1, GHRHR, HIF1A, HK2, PAM, STAT5B, USF2, VDR, VEGFA, EIF2AK3 |
772 | GO:0021983 | 0.00 | 4.76 | 9.18 | 17 | 22 | pituitary gland development | NR0B1, BMP4, BMPR1A, CDH1, ETS1, FGF8, GHRH, GHRHR, HES1, RBPJ, ISL1, SALL1, SIX3, SOX2, SOX3, SRD5A1, ALDH1A2 |
773 | GO:0033628 | 0.00 | 4.76 | 9.18 | 17 | 22 | regulation of cell adhesion mediated by integrin | ADA, DPP4, EFNA1, EPHA2, EPHA8, HRG, SERPINE1, PDE3B, PIK3CG, PTPN6, RAC3, CCL21, SNAI2, SYK, ADAM9, ITGB1BP1, CXCL13 |
774 | GO:0035094 | 0.00 | 4.76 | 9.18 | 17 | 22 | response to nicotine | ABAT, ATP1A2, AVP, BAD, BCL2, CHRNB2, CHRNB4, CNR1, IGF1, IGF2, IL13, KCNJ11, NTRK1, PENK, SHC1, STAR, RAPGEF3 |
775 | GO:0046638 | 0.00 | 4.76 | 9.18 | 17 | 22 | positive regulation of alpha-beta T cell differentiation | ADA, ANXA1, CD80, CD86, HLX, IFNG, IHH, ITPKB, PRKCZ, RARA, SHH, SYK, TNFSF4, AP3B1, RIPK2, AP3D1, IKZF1 |
776 | GO:0035666 | 0.00 | 4.74 | 14.61 | 27 | 35 | TRIF-dependent toll-like receptor signaling pathway | BIRC3, CASP8, CD14, CHUK, ATF2, DUSP4, DUSP7, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK3, MAPK8, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, UBB, UBE2D1, UBE2D2, CUL1, IKBKG, RIPK1, RIPK2, RPS6KA5 |
777 | GO:0002479 | 0.00 | 4.73 | 20.03 | 37 | 48 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | CD36, CYBA, FCGR1B, ITGAV, ITGB5, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, UBB, PSMF1, PSMD6, PSME3, SEC61B |
778 | GO:0071260 | 0.00 | 4.73 | 20.03 | 37 | 48 | cellular response to mechanical stimulus | AQP1, ATP1A2, BAD, BMP4, BMP6, BNIP3, CASP5, CASP8, TNFRSF8, CD40, COL1A1, CYBA, GADD45A, EDNRA, HIF1A, IGF2, IL1B, IL13, IRF1, ITGA2, ITGB1, KCNJ2, MAPK3, MAPK8, PTGER4, RAC1, SLC9A1, SOX9, TNFRSF1A, CRADD, TNFSF14, TNFRSF10B, TNFRSF10A, BCL10, BAG3, HDAC4, CASP8AP2 |
779 | GO:0030162 | 0.00 | 4.71 | 6.96 | 13 | 17 | regulation of proteolysis | C1QBP, C8B, EPHA7, MGMT, CFP, PRKACB, RFX4, RPS6KA2, SOX2, IFT88, LTBP4, TP63, KIAA0141 |
780 | GO:0007565 | 0.00 | 4.70 | 23.25 | 43 | 56 | female pregnancy | ADRA2C, ADRB2, AMBP, STS, BCL2, BYSL, CD38, COL16A1, COMT, DHODH, ETS1, GIP, GNAS, HPGD, IGF1, IGF2, IGFBP2, IGFBP5, IDO1, INSL4, ITGA2, OVGP1, OXT, PAPPA, PGF, PSG2, PSG3, PSG5, PSG6, PSG9, PSG11, PTGER4, PTHLH, PZP, RARA, RLN1, STAT5B, SULT1E1, UCN, FOSL1, RAMP2, CORIN, SLC38A3 |
781 | GO:0009615 | 0.00 | 4.70 | 17.82 | 33 | 43 | response to virus | ACTA2, BAD, BCL2L1, BCL3, CDK6, CHUK, CLU, DDX1, DDX3X, FGR, GATA3, GTF2F1, HMGA1, HSPB1, IFNGR1, ODC1, PENK, PSMA2, ABCE1, CCL22, XCL1, TPT1, TNFSF4, FOSL1, IKBKG, PRKRA, URI1, BANF1, DDX21, DCLK1, BCL2L11, IVNS1ABP, PIM2 |
782 | GO:0015844 | 0.00 | 4.68 | 16.28 | 30 | 39 | monoamine transport | ABAT, ADRA2C, ADRBK1, AGTR2, CHRNB2, CNR1, FCER1A, FCER1G, GDNF, GPM6B, FFAR3, KCNA2, OXT, P2RY1, PARK2, PCP4, PTGS1, RAB3B, SLC6A2, SLC6A4, SLC18A1, SLC22A1, SLC22A3, SLC22A2, SNCA, SYK, CADPS, PICK1, CARTPT, HRH3 |
783 | GO:0060840 | 0.01 | 4.68 | 5.41 | 10 | 13 | artery development | ACVR2B, ACVRL1, AP2B1, BMPR2, DNM2, LTBP1, SMAD6, SHH, SNX17, RAPGEF3 |
784 | GO:0032602 | 0.01 | 4.67 | 5.42 | 10 | 13 | chemokine production | F2RL1, ACKR1, IL10, IL18, S100A8, S100A9, SNAI2, TNFSF4, KLF4, TUSC2 |
785 | GO:0010107 | 0.00 | 4.67 | 10.85 | 20 | 26 | potassium ion import | ATP1A2, ATP12A, ATP1B3, FXYD2, ATP4A, KCNJ2, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ12, KCNJ13, KCNJ14, KCNJ15, KCNJ16, KCNE2, ABCC9 |
786 | GO:0030850 | 0.00 | 4.67 | 10.85 | 20 | 26 | prostate gland development | AHR, ALOX15B, ANXA1, APC, BMP4, CD44, ESR1, TNC, IGF1, IGF1R, SERPINF1, RARA, RXRA, SHH, SMARCC1, SOX9, STK11, UBE3A, TP63, FEM1B |
787 | GO:0051353 | 0.00 | 4.67 | 10.85 | 20 | 26 | positive regulation of oxidoreductase activity | ABL2, AGTR2, CALM3, SCARB1, CDH3, CYP27B1, DHFR, EDN2, ESR1, FCER2, GDNF, HIF1A, IFNG, IL1B, INS, KRAS, SNCA, VDR, FGF23, RGN |
788 | GO:0006884 | 0.01 | 4.66 | 5.43 | 10 | 13 | cell volume homeostasis | ADD1, AQP1, CLCN3, CLCN6, CLNS1A, E2F4, KCNN4, P2RX7, SLC6A12, SLC12A4 |
789 | GO:0007214 | 0.01 | 4.66 | 5.43 | 10 | 13 | gamma-aminobutyric acid signaling pathway | ATF4, CACNA1A, CACNB4, GABRA4, GABRB2, GABRE, GABRG1, GABRR1, GABRR2, GABBR2 |
790 | GO:0031954 | 0.01 | 4.66 | 5.43 | 10 | 13 | positive regulation of protein autophosphorylation | CALM3, ACE, INS, RAP2A, RAP2B, VEGFA, VEGFC, RASSF2, TOM1L1, RAD50 |
791 | GO:0032365 | 0.01 | 4.66 | 5.43 | 10 | 13 | intracellular lipid transport | ABCA1, ABCA2, SLC25A20, CPT1B, CPT2, PRKAB2, SCP2, STAR, ABCG1, COL4A3BP |
792 | GO:0032735 | 0.01 | 4.66 | 5.43 | 10 | 13 | positive regulation of interleukin-12 production | CD36, CD40, IFNG, IDO1, IRF1, IRF5, ISL1, TNFSF4, TNFSF9, RIPK2 |
793 | GO:0035855 | 0.01 | 4.66 | 5.43 | 10 | 13 | megakaryocyte development | EP300, FLI1, KIT, MEIS1, PIP4K2A, PTPN6, SRF, TAL1, ABI1, WASF2 |
794 | GO:0043691 | 0.01 | 4.66 | 5.43 | 10 | 13 | reverse cholesterol transport | ABCA1, APOA1, APOA4, APOC2, SCARB1, CETP, CLU, LCAT, LIPG, ABCG1 |
795 | GO:0050435 | 0.01 | 4.66 | 5.43 | 10 | 13 | beta-amyloid metabolic process | CLU, ACE, IDE, SORL1, PICALM, BECN1, HAP1, ABCA7, OLFM1, TMED10 |
796 | GO:0071364 | 0.01 | 4.66 | 5.43 | 10 | 13 | cellular response to epidermal growth factor stimulus | COL1A1, PAX2, PDPK1, SNAI2, SOX9, STAT5B, VIL1, BECN1, IQGAP1, BAG4 |
797 | GO:0071599 | 0.01 | 4.66 | 5.43 | 10 | 13 | otic vesicle development | COL2A1, EYA1, FGF3, FGF8, GATA3, PROX1, SIX1, SOX9, PAX8, HESX1 |
798 | GO:0098868 | 0.01 | 4.66 | 5.43 | 10 | 13 | bone growth | COL9A1, COMP, EVC, FGFR3, DDR2, RARA, RARB, STC1, CER1, CARM1 |
799 | GO:0050678 | 0.00 | 4.63 | 7.02 | 13 | 17 | regulation of epithelial cell proliferation | BAX, EDNRA, EDNRB, GPX1, HMGN1, IFNG, TACSTD2, SMAD3, PGR, SIX1, ALDH1A2, NR1D1, DEAF1 |
800 | GO:0046717 | 0.00 | 4.63 | 12.49 | 23 | 30 | acid secretion | ABAT, AGTR2, AGXT, ANXA1, BDKRB2, CACNA1A, CACNB4, ACE, ACSL4, HRH2, KCNQ1, OXT, P2RX4, P2RY2, SGK1, SYK, TRPC4, UCN, CYP4F2, TNFSF11, SLC9A3R1, ABCC4, STARD10 |
801 | GO:0030168 | 0.00 | 4.62 | 45.75 | 84 | 110 | platelet activation | A2M, ACTN4, ACTN1, ADRA2C, ALB, APOA1, AXL, SERPING1, DAGLA, CALM3, CALU, CD9, CD36, ENTPD2, CD40, CD63, CLU, COL1A1, COL3A1, DGKA, DGKB, DGKQ, F2R, FYN, GNA15, GNAI1, GNAI3, GNAQ, GNB1, GP1BA, GRB2, HGF, IGF1, IGF2, ITPR1, ITPR2, ITPR3, KNG1, LAMP2, P2RY1, SERPINE1, PDPK1, PF4, PF4V1, PFN1, SRGN, PRKCB, PRKCE, PRKCG, PRKCZ, MAPK3, PROS1, PTPN1, RAC1, RAC2, RAF1, RAP1A, CX3CL1, SHC1, SOD1, SOS1, SPARC, SRF, TRPC3, TUBA4A, VAV1, VEGFA, VEGFB, VEGFC, YWHAZ, FZD6, DGKE, DGKI, BCAR1, GNA14, WDR1, RASGRP2, ABCC4, RAPGEF3, VAV3, CAP1, PDPN, RAPGEF4, ADAMTS13 |
802 | GO:0002718 | 0.00 | 4.61 | 12.52 | 23 | 30 | regulation of cytokine production involved in immune response | ANGPT1, APOA1, BST2, BTK, CD36, CD74, CLC, F2RL1, FCER1G, FFAR3, IFNA2, IL10, PRKCZ, XCL1, TRAF2, TNFSF4, FZD5, SEMA7A, BCL10, ATG5, TRIL, SPON2, MALT1 |
803 | GO:0003151 | 0.00 | 4.61 | 12.52 | 23 | 30 | outflow tract morphogenesis | ATF2, EYA1, FGF8, GATA6, GJA5, HIF1A, HES1, RBPJ, ILK, ISL1, JUN, RARA, RARB, RYR1, SIX1, SOX11, TWIST1, VEGFA, WNT11, DHRS3, HAND2, CITED2, SEC24B |
804 | GO:1900544 | 0.00 | 4.61 | 26.71 | 49 | 64 | positive regulation of purine nucleotide metabolic process | ABCA1, ADCY7, ADCYAP1R1, ADORA2A, ADRB2, ARNT, AVP, AVPR2, CALCR, CALM3, EDNRA, FSHR, GCG, GHRH, GHRHR, GLP1R, GNAL, GNAS, GPD1, GUCA1A, GUCA1B, GUCA2A, GUCA2B, HIF1A, IGF1, INS, INSL3, NTRK1, NTRK2, P2RX7, P2RY11, PF4, PRKAA1, PRKCA, PTGER4, PTHLH, RAF1, RCVRN, STAT3, UCN, VIP, VIPR2, WFS1, GUCA1C, CALCRL, RAMP2, RAPGEF3, CAP2, CAP1 |
805 | GO:0072413 | 0.00 | 4.60 | 19.61 | 36 | 47 | signal transduction involved in mitotic cell cycle checkpoint | ATM, CDKN1A, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SOX4, UBB, CRADD, PSMF1, PSMD6, PSME3, CHEK2 |
806 | GO:1902402 | 0.00 | 4.60 | 19.61 | 36 | 47 | signal transduction involved in mitotic DNA damage checkpoint | ATM, CDKN1A, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SOX4, UBB, CRADD, PSMF1, PSMD6, PSME3, CHEK2 |
807 | GO:0007044 | 0.00 | 4.57 | 7.08 | 13 | 17 | cell-substrate junction assembly | ACTN1, BCL2, CTTN, ITGA2, ITGA5, LAMA5, PDPK1, TNS1, TRIP6, ARHGEF7, TAOK2, SORBS1, FERMT2 |
808 | GO:0060993 | 0.00 | 4.57 | 14.18 | 26 | 34 | kidney morphogenesis | BCL2, CD44, DLG1, EYA1, FGF1, FGF8, FOXD1, GATA3, GPC3, HOXD11, ILK, LAMA5, TACSTD2, PBX1, PGF, PRKX, PSPN, PTCH1, SHH, SIX1, SOX4, VEGFA, WNT1, WNT11, WNT2B, DCHS1 |
809 | GO:0001707 | 0.00 | 4.57 | 7.08 | 13 | 17 | mesoderm formation | ACVR1, BMPR2, EPHA2, EXT2, SMAD3, PRKAR1A, SNAI1, SRF, T, WNT11, EOMES, CHRD, HAND1 |
810 | GO:0060135 | 0.00 | 4.56 | 14.19 | 26 | 34 | maternal process involved in female pregnancy | ADCY7, ANGPT2, ARG1, PRDM1, BMPR2, BSG, CNR1, CTSV, CYP27B1, ESR1, GHSR, GJB2, HIF1A, IHH, ITGA3, ITGB1, JUNB, MEN1, PAM, PGR, PTGIS, RXRA, STC1, NR2F2, VDR, PRDX3 |
811 | GO:0015872 | 0.00 | 4.55 | 7.09 | 13 | 17 | dopamine transport | ABAT, CHRNB2, CNR1, GDNF, KCNA2, PARK2, PCP4, RAB3B, SLC18A1, SLC22A1, SLC22A3, SLC22A2, SNCA |
812 | GO:0021884 | 0.00 | 4.55 | 7.09 | 13 | 17 | forebrain neuron development | DCX, FGF8, GNAQ, OGDH, RAC1, RAC3, SOX1, CNTN2, UBB, SLIT2, RAPGEF2, SEMA3A, ATG7 |
813 | GO:0042744 | 0.00 | 4.55 | 7.09 | 13 | 17 | hydrogen peroxide catabolic process | APOA4, CAT, GPX1, GPX3, HBA1, HBA2, HP, SNCA, PRDX2, PXDN, EPX, PRDX6, PRDX3 |
814 | GO:0045003 | 0.00 | 4.55 | 7.09 | 13 | 17 | double-strand break repair via synthesis-dependent strand annealing | ATM, BARD1, BRCA1, BRCA2, RAD51, RAD51B, RAD51D, RBBP8, WRN, XRCC2, EXO1, RAD50, RAD51AP1 |
815 | GO:0046685 | 0.00 | 4.55 | 7.09 | 13 | 17 | response to arsenic-containing substance | ALAD, ATF3, ATF4, CDKN1A, CPOX, DDX3X, FECH, HMBS, TNFRSF11B, SERPINF1, RBM4, UROS, GSTO1 |
816 | GO:0055021 | 0.00 | 4.55 | 7.09 | 13 | 17 | regulation of cardiac muscle tissue growth | CAV3, CCNB1, CXADR, GATA4, GATA6, NRG1, RBPJ, KCNK2, TP73, COL14A1, WNT2, CTDP1, AKAP6 |
817 | GO:0060706 | 0.00 | 4.55 | 7.09 | 13 | 17 | cell differentiation involved in embryonic placenta development | ASCL2, PRDM1, CASP8, GJB5, KRT19, SNAI1, ST14, NR2F2, FZD5, EOMES, SOCS3, HAND1, SPINT2 |
818 | GO:0072488 | 0.00 | 4.55 | 7.09 | 13 | 17 | ammonium transmembrane transport | AQP1, SLC25A20, CPT1B, CPT2, PRKAB2, RHAG, RHCE, RHD, SLC12A2, SLC22A1, SLC22A3, SLC22A2, SLC22A5 |
819 | GO:1900408 | 0.00 | 4.55 | 7.09 | 13 | 17 | negative regulation of cellular response to oxidative stress | ATF4, GPX1, HGF, HIF1A, HP, HSPB1, INS, PARK2, PYCR1, SOD2, VNN1, BAG5, TRAP1 |
820 | GO:0006955 | 0.00 | 4.54 | 43.65 | 82 | 110 | immune response | ARHGDIB, AZGP1, BDKRB2, BMP6, BMPR1A, BPI, TNFRSF8, TNFSF8, CD70, ADGRE5, CCR1, CCR5, CCR8, ACKR2, CMKLR1, LTB4R, CNR2, CYP11B1, EDA, ETS1, FCGR3B, GAS6, GEM, CCR10, CXCL1, CXCL2, CXCL3, GZMH, HRH2, IGF1R, IK, IL1A, IL1R1, IL1RN, TNFRSF9, ITGAD, SMAD6, TNFRSF11B, ENPP1, ENPP2, ENPP3, PF4, PF4V1, EXOSC9, PRG2, RGS1, CXCL6, CXCL5, SP2, TNFRSF1A, TNFRSF1B, TNFRSF4, VIPR1, PXDN, IL1R2, IKBKAP, PRKRA, TNFSF11, S1PR4, TNFSF14, TNFSF12, TNFSF10, TNFSF9, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, IL18RAP, IL32, CXCL14, GTPBP1, TNFSF15, COL4A3BP, CHST4, PRG4, PRG3, PROCR, CCR9, IFI44L, IL24, PTGDR2 |
821 | GO:0032869 | 0.00 | 4.52 | 11.92 | 22 | 29 | cellular response to insulin stimulus | ALDOB, APRT, GHRHR, GHSR, GOT1, HIF1A, HMGCS2, IGF1, RAB8A, PRKCI, RAB13, RXRA, SRSF5, SLC2A4, SLC9A1, SRD5A1, STAR, USF1, YWHAG, KAT2B, RAB31, CAPN10 |
822 | GO:0007584 | 0.00 | 4.52 | 20.69 | 38 | 50 | response to nutrient | ABCA1, ADSL, ALB, ALDH3A1, APOA1, ASS1, SERPINC1, BRCA1, BRCA2, CNR1, COX4I1, CP, DAD1, ENSA, ERCC1, ACSL1, ACSL3, ACSL4, GCGR, HMGCL, HMGCR, HMGCS2, IGF1, IGFBP2, LDHA, TNFRSF11B, OXCT1, SLC6A4, SLC8A1, SLC16A1, SSTR2, STAR, SUOX, OGT, HAT1, AKR1C3, LIPG, SLC27A4 |
823 | GO:0008625 | 0.00 | 4.51 | 8.74 | 16 | 21 | extrinsic apoptotic signaling pathway via death domain receptors | BAD, BAX, BCL2, BID, CASP10, DDX3X, TNFRSF9, SORT1, TNFRSF1A, CRADD, TNFRSF18, TNFRSF10D, BAG3, KIAA0141, CASP8AP2, GABARAP |
824 | GO:0006775 | 0.00 | 4.50 | 17.53 | 32 | 42 | fat-soluble vitamin metabolic process | APOA1, APOA4, APOC2, AKR1C4, CLPS, CYP3A4, CYP24A1, CYP27B1, GPC4, GPC5, GFI1, GPC3, GPC1, IFNG, IL1B, RBP1, RBP2, RLBP1, SDC1, SDC2, SDC4, SNAI2, SNAI1, VDR, LRP8, CUBN, FGF23, CYP4F2, AKR1C3, ALDH1A2, SDC3, GPC6 |
825 | GO:0002478 | 0.00 | 4.49 | 20.78 | 38 | 50 | antigen processing and presentation of exogenous peptide antigen | CD36, CYBA, FCGR1B, ITGAV, ITGB5, ABCB1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, UBB, PSMF1, PSMD6, PSME3, SEC61B |
826 | GO:0032881 | 0.00 | 4.48 | 8.76 | 16 | 21 | regulation of polysaccharide metabolic process | ADRA1B, AP2A1, AKT2, CLTC, GCGR, HAS2, IGF1, IGF2, INS, KHK, ENPP1, PPP1CA, PTGER4, DYRK2, EPM2AIP1, SORBS1 |
827 | GO:0090004 | 0.00 | 4.48 | 8.76 | 16 | 21 | positive regulation of establishment of protein localization to plasma membrane | ARF6, DLG1, EPHA2, ACSL3, IFNG, ITGA3, ITGB1, PDPK1, PRKCI, VIL1, EZR, NRXN1, RAMP3, AGR2, SORBS1, RER1 |
828 | GO:0000187 | 0.00 | 4.46 | 20.85 | 38 | 50 | activation of MAPK activity | ADRA2C, ALK, C5, CD74, CSPG4, DUSP5, DUSP7, DUSP9, LPAR1, EFNA1, FPR1, GRM1, HGF, IL1B, IRAK1, IRAK2, ITGA1, KIT, NTF3, NTRK3, P2RX7, PDE6G, PDE6H, PIK3CB, PRKAA1, MAPK3, RPS27A, SHC1, SOD1, TP73, UBB, IKBKG, MAPKAPK5, MADD, PEA15, RIPK2, S1PR2, ERP29 |
829 | GO:0043200 | 0.00 | 4.46 | 10.41 | 19 | 25 | response to amino acid | AARS, ALAD, ALDOB, ARG1, ASNS, BAD, CDO1, CHUK, CPS1, CTGF, GIP, GLRB, GSS, HMBS, ICAM1, PIK3C3, PTGER4, PTN, AIFM1 |
830 | GO:0002791 | 0.00 | 4.45 | 55.09 | 100 | 132 | regulation of peptide secretion | ABAT, ADORA1, ADRA2C, SLC25A4, ANXA5, ARL2, ARNTL, BAD, BLK, CACNA1A, CACNA1E, CD38, CD74, CFTR, CHRM3, CNR1, EFNA5, ENSA, EPHA5, FGA, FGG, GCG, GHRH, GHRHR, GHSR, GIP, GLP1R, GLUD1, GLUL, GNAS, GPLD1, GPR27, FFAR1, FFAR3, HIF1A, HMGCR, FOXA2, HTR2C, IFNG, IL1B, INS, ISL1, ITPR1, ITPR2, ITPR3, KCNA5, KCNJ11, KCNS3, KISS1, OXCT1, PARK2, PCSK1, CDK16, PDE3B, PDE4C, PFKFB2, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCE, PTGER4, RAP1A, REST, RFX3, S100A8, S100A9, SLC2A2, SLC16A1, SNAP25, SOX4, SREBF1, STXBP1, ABCC8, TRH, TRPM2, UCN, VSNL1, PAX8, NR0B2, TNFSF11, IQGAP1, ARHGEF7, SYT7, HMGN3, NRXN1, STXBP5L, NR1D1, CLOCK, CARTPT, SPCS2, C2CD2L, NR1H4, RAPGEF3, RAPGEF4, CAPN10 |
831 | GO:0001990 | 0.00 | 4.44 | 10.43 | 19 | 25 | regulation of systemic arterial blood pressure by hormone | AGTR2, ANPEP, AVPR1B, AVPR2, CPA3, CTSG, CTSZ, CYBA, ACE, EDN2, EDN3, ENPEP, F2R, F2RL1, GJA5, PCSK5, RPS6KA2, ATP6AP2, CORIN |
832 | GO:0097530 | 0.00 | 4.43 | 24.21 | 44 | 58 | granulocyte migration | ANXA1, C1QBP, CD74, CMKLR1, CXADR, EDN2, EDN3, EDNRA, FCER1G, CXCL1, CXCL2, CXCL3, HRH1, IFNG, IL1B, ITGA1, ITGA9, PAWR, PDE4B, PDE4D, PIK3CG, PRKCA, PTGER4, RAC1, RAC2, S100A8, S100A9, S100A12, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, XCL2, SYK, VAV1, VEGFA, SCG2, EPX, TNFSF18, SLIT2, VAV3 |
833 | GO:0009617 | 0.00 | 4.41 | 67.23 | 122 | 162 | response to bacterium | ABCA1, ADH5, ALAD, ARG1, ASS1, ATP4B, AXL, PRDM1, BMP6, BYSL, TSPO, CASP8, CASP9, CD6, CD14, CD80, CD86, TNFRSF8, SCARB1, ENTPD2, CD40, CHUK, CCR5, CNP, CNR1, CNR2, COMT, CPS1, CSF2, CX3CR1, CYP1A2, CYP27B1, CD55, DCN, DNMT1, EDNRA, EDNRB, F2R, F3, GFI1, GPX1, CXCL1, CXCL2, CXCL3, HCK, HIF1A, HMGCS2, ICAM1, IGF1, IL1B, IL10RA, IL12RB2, IL13, TNFRSF9, IL18, IDO1, IRAK1, IRAK2, IRF5, JUN, JUNB, JUND, KCNJ8, CD180, MGST2, CITED1, NRF1, TNFRSF11B, P2RY2, PAWR, PDE4B, PDE4D, PENK, PF4, PF4V1, SERPINB9, PRKCA, PRKCE, MAPK3, MAPK8, EIF2AK2, PROS1, PTAFR, PTGER1, PTGER4, RARA, RPS6KA3, CXCL5, SELE, SNCA, SPARC, STAR, STAT5B, ABCC8, TNFAIP3, TNFRSF1B, TNFSF4, TNFRSF4, SCGB1A1, VIL1, FZD5, OGT, PPM1D, PARG, ADAM9, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, BCL10, SOCS3, LITAF, NR1D1, NR1H4, IL18BP, TRIB1, BAIAP2, GJB6, MALT1, PRDX3, IL24 |
834 | GO:0071377 | 0.00 | 4.41 | 12.10 | 22 | 29 | cellular response to glucagon stimulus | ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ARG1, ASS1, CPS1, GCG, GCGR, GLP1R, GNAS, GNB1, GNB2, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, GLP2R |
835 | GO:0045665 | 0.00 | 4.38 | 15.41 | 28 | 37 | negative regulation of neuron differentiation | CNTF, DDX6, DTX1, EDNRB, EIF4E, FOXA2, HES1, IL1B, ISL1, ITGB1, MEIS1, PBX1, RAP1GAP, REST, SHH, SIX3, SLC6A4, SOX2, SOX3, SOX9, CNTN2, NR2E1, TP73, TTC3, PHOX2B, ZNF536, OLIG2, HMG20A |
836 | GO:0034340 | 0.00 | 4.36 | 17.11 | 31 | 41 | response to type I interferon | ADAR, BST2, IFI6, UBE2K, HSP90AB1, IFIT1, IFIT3, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IRF1, IRF2, IRF5, ISG20, OAS1, OAS2, OAS3, PTPN1, PTPN6, SHMT2, SP100, STAT2, TYK2, OASL, SOCS3, IFITM3, IFITM2, CDC37, USP18 |
837 | GO:0060349 | 0.00 | 4.36 | 17.11 | 31 | 41 | bone morphogenesis | ACP5, BMP4, BMP6, BMPR2, RUNX2, SERPINH1, CDX1, COL1A1, COL2A1, COL9A1, COL10A1, COMP, DLX5, FGFR3, GNAS, HAS2, HOXD11, INPPL1, INSIG1, LTF, PAX1, PTHLH, RARA, RARB, SOX9, STC1, T, TWIST1, DHRS3, CER1, CARM1 |
838 | GO:0010243 | 0.00 | 4.35 | 10.74 | 20 | 27 | response to organonitrogen compound | ADRB2, AGTR2, ATP4B, CCND1, TSPO, CDKN1A, CNR2, DBH, TRDMT1, FLT3, HLCS, HPRT1, IRAK1, ITGA2, MGST2, PDE1B, PTGS1, RANBP2, TP73, KYNU |
839 | GO:0051701 | 0.00 | 4.34 | 28.70 | 52 | 69 | interaction with host | ADRBK1, ANPEP, AXL, CAV2, CD80, CD86, SCARB1, SCARB2, CCR5, CR1, CR2, CXADR, CD55, DPP4, EFNB2, EPS15, FCN1, GAS6, GYPA, ICAM1, IDE, IFIT1, IFNA2, ITGA2, ITGA5, ITGB1, ITGB5, LTF, CD46, PVR, SERPINB3, SELPLG, SLAMF1, SLC10A1, SLC20A2, SLC22A5, DYNLT1, TMPRSS2, TNFRSF4, TYRO3, UVRAG, TRIM25, FCN3, VAMP8, XPR1, IFITM3, TRIM38, SIVA1, IFITM2, WWP1, WWP2, TUSC2 |
840 | GO:0072401 | 0.00 | 4.34 | 20.45 | 37 | 49 | signal transduction involved in DNA integrity checkpoint | ATM, CDC5L, CDKN1A, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SOX4, UBB, CRADD, PSMF1, PSMD6, PSME3, CHEK2 |
841 | GO:0061138 | 0.00 | 4.34 | 30.38 | 55 | 73 | morphogenesis of a branching epithelium | ACVR1, AGTR2, AREG, BAX, BCL2, CAV3, CTSZ, DLG1, EDNRA, EPHA2, ETV4, ETV5, EYA1, FGF1, FOXD1, GDNF, B4GALT1, GPC3, HHEX, FOXA2, HOXD11, TNC, IHH, ILK, KDR, KRAS, TACSTD2, CITED1, PAX2, PBX1, PGF, PGR, PPP1CA, PSPN, PROX1, PTCH1, SALL1, SIX1, SLC12A2, SOX2, SOX9, SOX10, SRF, VDR, VEGFA, WNT1, WNT2, WNT2B, PAX8, TP63, DCHS1, SLIT2, SEMA3E, SIX2, PHB2 |
842 | GO:0071363 | 0.00 | 4.32 | 40.84 | 75 | 101 | cellular response to growth factor stimulus | ADCYAP1R1, ADORA2A, AP2A1, AP2B1, ANGPT2, ARHGAP4, BGLAP, BYSL, CAT, AP2M1, AP2S1, CLU, CLTA, DDC, DTYMK, DUSP4, ECT2, ELK1, EMD, ERN1, FGD1, FLT3, FLT4, GAS1, GAS6, HAS1, HAS2, HGF, HSPB1, HTR3A, IRAK1, KDR, NTRK3, PAX9, PCSK5, PPP2R5D, PRKCI, PRKD1, MAPK8, PTN, RAC1, RALA, RAP1GAP, RPS6KA1, RPS6KA2, RPS6KA3, ITSN1, SMPD2, SOS2, SPARC, SRD5A1, STAT3, TNFRSF1B, TRIO, TWIST1, LRP8, URI1, RIPK1, RIPK2, NRP2, HDAC3, ARHGEF7, KALRN, HAP1, ARHGEF2, RPS6KA5, KLF4, ARHGEF6, BCAR1, ARHGEF17, BCL2L11, RAMP2, VAV3, AKAP13, TWF2 |
843 | GO:0048520 | 0.00 | 4.31 | 30.46 | 55 | 73 | positive regulation of behavior | ADAM10, AKT2, ALB, BMPR2, C1QBP, CD74, CCR1, CMKLR1, S1PR1, LPAR1, EDN2, EDN3, EDNRA, F2RL1, F3, F7, GAS6, GHRH, GHRHR, CXCL1, CXCL2, CXCL3, HSPB1, IL1B, ITGA2, KDR, SMAD3, NTF3, NTRK3, SERPINE1, PENK, PF4, PF4V1, PRKCA, PRKD1, PTGER4, RAC1, RAC2, CCL21, CXCL6, CXCL5, XCL1, CX3CL1, NR2C2, UCN, VEGFA, VEGFB, VEGFC, SCG2, TNFSF14, TNFSF18, SLIT2, CXCL14, CREB3, CXCL13 |
844 | GO:0097191 | 0.00 | 4.27 | 8.27 | 15 | 20 | extrinsic apoptotic signaling pathway | ACVR1B, CD14, CD70, DBH, FGFR3, IFNG, KRT18, SMAD3, P2RX7, PDPK1, TNFRSF1B, TRAF1, PARP2, RNF41, SIVA1 |
845 | GO:0019932 | 0.00 | 4.26 | 16.60 | 30 | 40 | second-messenger-mediated signaling | ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADCYAP1R1, DGKQ, EDNRB, EIF4EBP2, EPHA5, GHRH, GHRHR, GIP, GLP1R, GNAI1, GNAS, PDE3A, PDE3B, PDE4A, PDE7A, PF4, PPP2R1A, PRKG1, RGS2, SOX9, RAPGEF2, RIMS2, RAPGEF3, PDE10A, RAPGEF4 |
846 | GO:0009749 | 0.00 | 4.25 | 13.28 | 24 | 32 | response to glucose | ACVR2B, ANGPT2, COL6A2, CTGF, CTSV, EIF2B1, ENSA, GIP, GLUL, GYS2, KHK, LDHA, PFKFB2, PRKCQ, SLC2A2, SLC8A1, SREBF1, TRH, NR0B2, EIF2B4, EIF2B3, EIF2B2, EIF2B5, TXNIP |
847 | GO:0010001 | 0.00 | 4.25 | 8.29 | 15 | 20 | glial cell differentiation | AKT2, DTX1, EGR2, EMX1, GAP43, GPC1, IGF1, ILK, PAX2, RELN, SOD1, SOX2, SOX4, PHOX2B, PICK1 |
848 | GO:0007623 | 0.00 | 4.25 | 14.95 | 27 | 36 | circadian rhythm | ATP7B, AVP, KLF9, CDK4, CRX, DDC, DDX5, DHX9, DYRK1A, EGR3, EP300, F7, JUN, JUND, NTRK1, NTRK2, NTRK3, SERPINE1, RPS27A, SKP1, SLC6A4, SLC9A3, SREBF1, TYMS, UBB, CUL1, PROKR1 |
849 | GO:0045471 | 0.00 | 4.24 | 30.02 | 54 | 72 | response to ethanol | ABAT, ADCYAP1R1, ALAD, ATP5G3, AVP, BAD, CCND1, BGLAP, CASP8, CAT, CCNE1, CD14, CDO1, CHRNB2, CNR1, DBH, DNMT1, EEF2, EIF4EBP1, EPS8, FECH, FYN, GATA3, GK, GOT2, GRIN2A, HMGCR, HMGCS2, HTR3A, TNC, ICAM1, IGF2, IL1B, IL13, MGMT, NTRK1, NTRK3, OGG1, OXCT1, PENK, RARA, RXRA, S100A8, ST6GAL1, SLC2A4, SOD1, SPARC, STAR, STAT3, STAT5B, TRH, TYMS, GGH, SETDB1 |
850 | GO:0043583 | 0.02 | 4.24 | 4.98 | 9 | 12 | ear development | SHROOM2, BCL2, MAPK3, RPL38, SALL1, TWIST1, PRKRA, BCL2L11, SIX2 |
851 | GO:0022617 | 0.00 | 4.23 | 28.38 | 51 | 68 | extracellular matrix disassembly | A2M, ADAM10, BMP1, BSG, CAPN1, CD44, CDH1, COL1A1, COL2A1, COL3A1, COL4A3, COL4A4, COL4A5, COL4A6, COL5A1, COL5A2, COL6A2, COL6A3, COL9A1, COL9A3, COL10A1, COL11A1, COL12A1, COL16A1, COL17A1, COL19A1, CTSD, CTSG, CTSK, CTSV, CTSS, DCN, DPP4, ELN, ETS1, FAP, FBN1, FGFR4, HPN, KLK2, KLKB1, LAMA3, LAMA5, DDR2, KLK7, TPSAB1, COL14A1, ADAM15, ADAM9, ADAMTS4, ADAMTS5 |
852 | GO:0046718 | 0.00 | 4.23 | 28.38 | 51 | 68 | viral entry into host cell | ADRBK1, ANPEP, APCS, AXL, CAV2, CD4, CD80, CD86, SCARB1, SCARB2, CCR5, CR1, CR2, CXADR, CD55, DPP4, EFNB2, EPS15, FCN1, GAS6, GYPA, ICAM1, IDE, IFNA2, ITGA2, ITGA5, ITGAV, ITGB1, ITGB5, CD46, PVR, SERPINB3, SELPLG, SLAMF1, SLC10A1, SLC20A2, DYNLT1, TMPRSS2, TNFRSF4, TYRO3, UVRAG, TRIM25, FCN3, VAMP8, XPR1, IFITM3, TRIM38, SIVA1, IFITM2, WWP1, WWP2 |
853 | GO:0048813 | 0.00 | 4.23 | 9.98 | 18 | 24 | dendrite morphogenesis | ABL2, RERE, CACNA1A, CACNA1F, CTNNA2, DCX, CELSR2, FYN, HPRT1, ITGB1, MAP6, SLC11A2, RAC1, PICALM, KLF7, DCLK1, FARP1, SEMA3A |
854 | GO:0030282 | 0.00 | 4.22 | 8.32 | 15 | 20 | bone mineralization | ASGR2, FGFR3, GPC3, IGF1, PHEX, PTH1R, PTN, KLF10, CLEC3B, TUFT1, WNT11, CER1, EIF2AK3, MINPP1, GPNMB |
855 | GO:0043154 | 0.00 | 4.22 | 21.70 | 39 | 52 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | AKT2, BIRC3, XIAP, BIRC5, AQP1, AVP, CASP8, CD44, CDKN2D, CRYAB, CSNK2A1, DDX3X, DHCR24, DPEP1, IFI6, GAS6, SFN, GPX1, HGF, PAX2, SERPINB9, RAF1, RAG1, RPS6KA1, RPS6KA3, SIAH2, SNCA, TRAF2, VEGFA, VIL1, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR, KLF4, PRDX3 |
856 | GO:0070555 | 0.01 | 4.22 | 6.66 | 12 | 16 | response to interleukin-1 | AES, ANXA1, CD38, CYBA, ETS1, CITED1, PRKCA, PRKCI, SELE, SNCA, RIPK2, HDAC4 |
857 | GO:0070542 | 0.02 | 4.22 | 4.99 | 9 | 12 | response to fatty acid | ALAD, BAD, CAT, CD36, CTGF, ACSL1, FFAR1, HMGCL, PTGS1 |
858 | GO:0030104 | 0.00 | 4.22 | 18.36 | 33 | 44 | water homeostasis | ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ALOX12, AQP1, AVP, AVPR2, FLG, GHRHR, GNAS, SFN, HAS2, IGF1, KRT1, KRT16, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, SCNN1A, SCNN1B, SCNN1G, SLC6A12, SRF, WFS1, CYP4F2, TP63, RAB11A |
859 | GO:0045582 | 0.01 | 4.21 | 6.66 | 12 | 16 | positive regulation of T cell differentiation | BAD, CD74, EGR3, GATA3, IL1B, IL2RA, CD46, RAG1, STAT5B, TNFSF9, IL1RL2, VNN1 |
860 | GO:0007585 | 0.01 | 4.21 | 6.66 | 12 | 16 | respiratory gaseous exchange | BPGM, CFTR, COX5B, COX15, CSF2RB, EDNRA, ELN, FUT8, SFTPB, SFTPD, TMPRSS11D, TRAF4 |
861 | GO:0031018 | 0.00 | 4.21 | 8.33 | 15 | 20 | endocrine pancreas development | ANXA1, CLU, GIP, FOXA2, HNF4G, ONECUT1, HES1, IAPP, INS, PDE3B, SLC2A2, SOX4, SOX9, EIF2AK3, ONECUT2 |
862 | GO:1903793 | 0.01 | 4.21 | 6.67 | 12 | 16 | positive regulation of anion transport | CFTR, CHRNB2, GDNF, PCP4, PTAFR, RAB3B, SLC34A1, SLC18A1, TACR2, VAMP8, ABCA7, ATP8A1 |
863 | GO:0014047 | 0.01 | 4.21 | 6.67 | 12 | 16 | glutamate secretion | GLS, NTRK2, RAB3A, SLC1A6, SLC1A7, SNAP25, STXBP1, SYT1, TRPV1, UNC13B, GIPC1, CPLX1 |
864 | GO:0061515 | 0.01 | 4.21 | 6.67 | 12 | 16 | myeloid cell development | ANXA2, ATP6AP1, EPB42, LTF, SLC11A2, ARID4A, RHAG, TYROBP, TNFSF11, PTBP3, TSPAN2, KLF2 |
865 | GO:0035249 | 0.02 | 4.21 | 5.00 | 9 | 12 | synaptic transmission, glutamatergic | ADRB2, CACNA1A, CACNB4, CDH8, CDK5, CLCN3, GRID2, PARK2, UNC13B |
866 | GO:0002712 | 0.00 | 4.20 | 10.02 | 18 | 24 | regulation of B cell mediated immunity | BTK, C3, CD28, CD40, CR1, FCER1A, FCER1G, FCER2, HPX, IFNG, IL10, PTPN6, XCL1, TNFSF4, UNG, WHSC1, TNFSF13, IL27RA |
867 | GO:1902743 | 0.00 | 4.20 | 10.02 | 18 | 24 | regulation of lamellipodium organization | AQP1, CAPZB, DNM2, EPHA2, HRG, ENPP2, RAC1, RAC2, RREB1, CLRN1, VIL1, WNT1, ARHGEF7, SLIT2, HDAC4, ARPC2, WASF2, TWF2 |
868 | GO:0042304 | 0.02 | 4.20 | 5.00 | 9 | 12 | regulation of fatty acid biosynthetic process | ACADL, ACADVL, BRCA1, INSIG1, PDK4, PRKAB2, STK11, ERLIN1, ERLIN2 |
869 | GO:0019228 | 0.00 | 4.20 | 8.35 | 15 | 20 | neuronal action potential | DPP6, IFNG, KCNA1, KCNA2, KCND2, P2RX3, P2RX4, PAWR, SCN1A, SCN3A, SCN5A, SCN8A, SCN10A, KCNMB2, SCN11A |
870 | GO:0045581 | 0.00 | 4.20 | 8.35 | 15 | 20 | negative regulation of T cell differentiation | ANXA1, BMP4, CD74, CDKN2A, CTLA4, CYLD, DTX1, ERBB2, HLX, IFNA2, IHH, IRF1, SHH, TNFSF4, TNFSF18 |
871 | GO:0051281 | 0.00 | 4.20 | 8.35 | 15 | 20 | positive regulation of release of sequestered calcium ion into cytosol | BAX, CALM3, EDNRA, F2R, GSTM2, IL13, NTSR1, PDPK1, XCL1, SNCA, TRPC1, HAP1, GSTO1, AKAP6, TRDN |
872 | GO:0071622 | 0.00 | 4.20 | 8.35 | 15 | 20 | regulation of granulocyte chemotaxis | C1QBP, CD74, CMKLR1, EDNRA, CXCL1, CXCL2, CXCL3, IL1B, RAC1, RAC2, CCL21, XCL1, CX3CL1, TNFSF18, SLIT2 |
873 | GO:0001961 | 0.01 | 4.20 | 6.68 | 12 | 16 | positive regulation of cytokine-mediated signaling pathway | AXL, CD74, GAS6, GFI1, HIF1A, UBE2K, HPX, PARK2, TRAF2, RIPK2, CPNE1, AGPAT2 |
874 | GO:0002675 | 0.01 | 4.20 | 6.68 | 12 | 16 | positive regulation of acute inflammatory response | C3, CNR1, F12, FCER1A, FCER1G, FFAR3, IL1B, KLKB1, PIK3CG, TAC1, ZP3, TNFSF11 |
875 | GO:0002828 | 0.01 | 4.20 | 6.68 | 12 | 16 | regulation of type 2 immune response | ANXA1, CD86, CD74, ECM1, HLX, IFNA2, IDO1, PRKCZ, RARA, XCL1, TNFSF4, IL27RA |
876 | GO:0006182 | 0.01 | 4.20 | 6.68 | 12 | 16 | cGMP biosynthetic process | AQP1, GUCA1A, GUCA1B, GUCA2A, GUCA2B, GUCY1B3, GUCY2C, GUCY2F, GUCY2D, HTR2C, RCVRN, GUCA1C |
877 | GO:0038084 | 0.01 | 4.20 | 6.68 | 12 | 16 | vascular endothelial growth factor signaling pathway | CD63, DCN, FLT1, FLT3, FLT4, HRG, HSPB1, KDR, PRKD1, VEGFA, NRP2, ADAMTS3 |
878 | GO:0044364 | 0.01 | 4.20 | 6.68 | 12 | 16 | disruption of cells of other organism | ALB, BAD, CTSG, DEFA1, F2RL1, FCER2, IFNG, P2RX7, S100A12, BCL2L11, GNLY, TUSC2 |
879 | GO:1900740 | 0.01 | 4.20 | 6.68 | 12 | 16 | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | BAD, BCL2, BID, CASP8, SFN, PPP3R1, MAPK8, YWHAG, YWHAH, YWHAZ, DYNLL1, BCL2L11 |
880 | GO:2000144 | 0.01 | 4.20 | 6.68 | 12 | 16 | positive regulation of DNA-templated transcription, initiation | AHR, JUN, PSMC1, PSMC3, PSMC4, PSMC5, SRF, HNF1A, TWIST1, FOSL1, BCLAF1, IKZF1 |
881 | GO:0001783 | 0.02 | 4.20 | 5.01 | 9 | 12 | B cell apoptotic process | ADA, BAX, BTK, CD74, IL10, BCL10, AURKB, BCL2L11, TRAF3IP2 |
882 | GO:0006855 | 0.02 | 4.20 | 5.01 | 9 | 12 | drug transmembrane transport | ATP8B1, ABCB1, SLC18A1, SLC22A1, SLC22A3, SLC22A2, SLC22A5, ABCG2, EBP |
883 | GO:0009263 | 0.02 | 4.20 | 5.01 | 9 | 12 | deoxyribonucleotide biosynthetic process | ADK, DTYMK, DUT, GUK1, RRM1, RRM2, SHMT1, TYMS, TBPL1 |
884 | GO:0014059 | 0.02 | 4.20 | 5.01 | 9 | 12 | regulation of dopamine secretion | ABAT, CHRNB2, CNR1, GDNF, KCNA2, PARK2, PCP4, SLC18A1, SNCA |
885 | GO:0019430 | 0.02 | 4.20 | 5.01 | 9 | 12 | removal of superoxide radicals | APOA4, CD36, DHFR, FANCC, SOD1, SOD2, PRDX2, RGN, FBLN5 |
886 | GO:0021952 | 0.02 | 4.20 | 5.01 | 9 | 12 | central nervous system projection neuron axonogenesis | CHRNB2, DCC, DCX, EPHA4, EPHB1, EPHB3, NR2E1, DCLK1, SLIT2 |
887 | GO:0035116 | 0.02 | 4.20 | 5.01 | 9 | 12 | embryonic hindlimb morphogenesis | ALX3, BMP4, FGF8, GPC3, GNAS, AFF3, RARB, SHH, TWIST1 |
888 | GO:0042136 | 0.02 | 4.20 | 5.01 | 9 | 12 | neurotransmitter biosynthetic process | ACHE, ALDH2, ALDH9A1, DAGLA, COMT, GAD1, GAD2, PAH, SLC22A2 |
889 | GO:0042558 | 0.02 | 4.20 | 5.01 | 9 | 12 | pteridine-containing compound metabolic process | DHFR, SARDH, PAH, QDPR, SHMT1, SHMT2, TYMS, GGH, ALDH1L1 |
890 | GO:0045822 | 0.02 | 4.20 | 5.01 | 9 | 12 | negative regulation of heart contraction | ADORA1, ADRBK1, AGTR2, ATP1A2, PDE4D, PIK3CG, PLN, TAC1, PDE5A |
891 | GO:0048070 | 0.02 | 4.20 | 5.01 | 9 | 12 | regulation of developmental pigmentation | BAX, BCL2, EDN3, GNAQ, IHH, KIT, KITLG, ZEB2, BCL2L11 |
892 | GO:0061037 | 0.02 | 4.20 | 5.01 | 9 | 12 | negative regulation of cartilage development | BMP4, EFEMP1, PTHLH, RARA, RARB, SNAI2, SOX9, WNT11, ADAMTS7 |
893 | GO:0070987 | 0.02 | 4.20 | 5.01 | 9 | 12 | error-free translesion synthesis | RFC1, RFC2, RFC3, RFC4, RFC5, RPA3, RPS27A, UBB, UFD1L |
894 | GO:0071636 | 0.02 | 4.20 | 5.01 | 9 | 12 | positive regulation of transforming growth factor beta production | ATF2, LUM, SMAD3, CD46, XCL1, CX3CL1, WNT11, SERPINB7, ATP6AP2 |
895 | GO:0071731 | 0.02 | 4.20 | 5.01 | 9 | 12 | response to nitric oxide | AQP1, BMP4, DNM2, DPEP1, GUCY1B3, IL1R1, MAPK8, TRAF2, AIFM1 |
896 | GO:0086064 | 0.02 | 4.20 | 5.01 | 9 | 12 | cell communication by electrical coupling involved in cardiac conduction | ATP1A2, CALM3, GJA5, HRC, PDE4D, PRKACA, RYR2, SLC8A1, TRDN |
897 | GO:1901881 | 0.02 | 4.20 | 5.01 | 9 | 12 | positive regulation of protein depolymerization | CFL2, F2RL1, SLN, SPAST, VIL1, SYNJ1, WDR1, KATNB1, STMN2 |
898 | GO:1902259 | 0.02 | 4.20 | 5.01 | 9 | 12 | regulation of delayed rectifier potassium channel activity | KCNE1, KCNQ1, KCNS1, KCNS2, SUMO1, AKAP7, AKAP6, KCNE2, KCNE3 |
899 | GO:1903543 | 0.02 | 4.20 | 5.01 | 9 | 12 | positive regulation of exosomal secretion | IFNG, SDC1, SDC4, SDCBP, TSG101, RAB7A, STAM, PDCD6IP, SNF8 |
900 | GO:0048583 | 0.00 | 4.16 | 7.90 | 15 | 21 | regulation of response to stimulus | ADK, CHRNB2, GABRA4, GTF2I, KCNA2, SCN5A, TACR3, TNNC1, TNNT1, TRH, COL14A1, AKAP1, PER3, CTDP1, HDAC4 |
901 | GO:0046903 | 0.00 | 4.12 | 18.10 | 33 | 45 | secretion | ANPEP, ANXA2, APRT, AQP5, ATP2B2, ATP7B, AVPR2, CCND1, CA2, CDO1, CHRM1, CHUK, COMT, COPA, DHODH, CELSR2, SLC29A1, GUCA1B, GUCA2B, NRG1, HK2, PRKCI, STAT5B, STC1, TP73, TPD52, TRPC1, USF2, VDR, SLC22A6, FBLN5, AGR2, CORIN |
902 | GO:0006521 | 0.00 | 4.11 | 19.60 | 35 | 47 | regulation of cellular amino acid metabolic process | APC, BHMT, INS, OAZ1, OAZ2, ODC1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PSMF1, PSMD6, PSME3 |
903 | GO:1900046 | 0.00 | 4.10 | 19.61 | 35 | 47 | regulation of hemostasis | ABAT, ADRB2, ALOX12, ANXA2, ANXA5, APOH, SERPINC1, SERPING1, CD36, F2R, F2RL1, F3, F7, F12, FAP, FCER1G, FGA, FGG, GP1BA, FOXA2, HRG, KLKB1, KNG1, KRT1, SERPINE1, PRKCA, PRKCQ, PRKG1, PROC, PROS1, S100A9, SELP, SYK, USF1, VTN |
904 | GO:0034284 | 0.00 | 4.10 | 14.52 | 26 | 35 | response to monosaccharide | ACVR2B, ALDOB, ANGPT2, COL6A2, CTGF, CTSV, EIF2B1, ENSA, GIP, GLUL, GYS2, HMGCS2, KHK, LDHA, PFKFB2, PRKCQ, SLC2A2, SLC8A1, SREBF1, TRH, NR0B2, EIF2B4, EIF2B3, EIF2B2, EIF2B5, TXNIP |
905 | GO:0072599 | 0.00 | 4.10 | 32.55 | 58 | 78 | establishment of protein localization to endoplasmic reticulum | FAU, RPL10A, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, RYR2, SRP9, SRP14, SRP19, SRP68, SSR1, SSR3, RPL14, RPL23, SPCS2, SEC61B, RPL35, SEC63 |
906 | GO:0009636 | 0.00 | 4.09 | 25.73 | 46 | 62 | response to toxic substance | AHR, ALAD, ARG1, ASNS, ASS1, BAX, BCL2, CDH1, CDK4, CDKN1A, CHKA, CHUK, CNP, CPS1, CYP2F1, DNMT1, DNMT3A, DNMT3B, ERCC6, GRIA4, GUCY2C, HIF1A, HSPA9, MGMT, PARK2, PENK, MAPK3, EIF2AK2, RAD51, SCN8A, SDC1, SHC1, SLC6A4, SRD5A1, SRF, TYMS, XPA, OGT, AIFM1, SLC22A8, HDAC6, DHRS2, GLYAT, CERS1, ADAMTS13, INMT |
907 | GO:0006959 | 0.00 | 4.09 | 27.46 | 49 | 66 | humoral immune response | A2M, ANG, KLK3, BCL2, BST2, CD28, CD37, CD59, DEFA1, DMBT1, GPR183, FAU, FCN1, FCN2, FGA, GATA3, CFHR1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, RBPJ, KRT1, LTF, CFP, PROS1, PSMB10, RNASE3, RPL39, SEMG1, ST6GAL1, SLPI, TAC1, VIP, VTN, HIST1H2BG, HIST1H2BF, HIST2H2BE, FCN3, HIST1H2BJ, EBI3, SPON2, CXCL13, TRAF3IP2, SPINK5, VSIG4 |
908 | GO:0007492 | 0.00 | 4.07 | 16.28 | 29 | 39 | endoderm development | BMPR1A, COL5A1, COL5A2, COL11A1, COL12A1, DUSP1, DUSP4, DUSP5, EXT1, FGF8, GATA4, GATA6, HHEX, ONECUT1, HOXC11, HSBP1, ITGA4, ITGA5, ITGA7, ITGAV, ITGB5, LAMA3, SMAD3, OTX2, PAX9, PTHLH, SOX2, VTN, EOMES |
909 | GO:0033209 | 0.00 | 4.05 | 33.72 | 60 | 81 | tumor necrosis factor-mediated signaling pathway | TNFRSF17, TNFRSF8, CD40, CD70, EDA, TNFRSF9, KRT18, TNFRSF11B, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RELB, SKP1, SMPD2, TNFRSF1B, TNFSF4, TNFRSF4, NSMAF, CUL1, TNFSF11, TNFSF14, TNFSF13, TNFSF12, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, TNFSF18, UBA3, PSMF1, BAG4, PSMD6, TNFSF15, PSME3, TNFSF13B, EDAR |
910 | GO:0014068 | 0.00 | 4.05 | 14.61 | 26 | 35 | positive regulation of phosphatidylinositol 3-kinase signaling | ANGPT1, CAT, CBL, CD28, DCN, F2R, F2RL1, FGR, FLT1, FLT3, FSHR, FYN, HCLS1, HGF, NRG1, IGF1, INS, KDR, KIT, NTRK2, RELN, PTPN6, SELP, SOX9, UBE3A, BECN1 |
911 | GO:0045761 | 0.00 | 4.05 | 14.61 | 26 | 35 | regulation of adenylate cyclase activity | ADCYAP1R1, ADORA2A, ADRB2, AVPR2, CALCR, CALM3, EDNRA, EDNRB, FSHR, GALR1, GHRHR, GLP1R, GNAI3, GNAL, GNAS, NTRK1, NTRK2, P2RY11, PRKCA, RAF1, VIP, VIPR2, WFS1, GABBR2, CAP2, CAP1 |
912 | GO:0048678 | 0.00 | 4.05 | 14.61 | 26 | 35 | response to axon injury | APOA1, ARF4, ARG1, BAX, BCL2, TSPO, CALU, CTNNA1, DHFR, DPYSL3, EPHA4, FGFR3, GIP, TNC, ISL1, JUN, KCNK2, NTRK1, NTRK3, NTS, RXRA, SOD1, TNR, KLF4, NREP, CHST3 |
913 | GO:0070527 | 0.00 | 4.05 | 14.61 | 26 | 35 | platelet aggregation | ABAT, ACTB, ACTG1, ADRB2, ALOX12, CSRP1, FGA, FGG, FLNA, GAS6, GNAS, HSPB1, ILK, PIK3CB, PIK3CG, PRKCA, PRKCQ, PRKG1, PTPN6, RAP2B, STXBP1, STXBP3, SYK, TYRO3, VCL, FIBP |
914 | GO:0006595 | 0.00 | 4.05 | 25.87 | 46 | 62 | polyamine metabolic process | ARG1, ARG2, ASL, ASS1, CKM, CPS1, DHPS, GAMT, GOT1, OAZ1, OAZ2, ODC1, OTC, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, SAT1, SLC6A8, SMS, PSMF1, PSMD6, SLC25A15, PSME3 |
915 | GO:0048010 | 0.00 | 4.05 | 63.72 | 113 | 153 | vascular endothelial growth factor receptor signaling pathway | ACTB, ACTG1, ANGPT1, AXL, BMPR2, CALM3, CAMK2A, CAMK2G, CDC42, CSF2, CSF2RB, CTNNA1, CTNND1, CYBA, HBEGF, DUSP5, DUSP7, DUSP9, ERBB2, EREG, FGF1, FGF3, FGF6, FGF7, FGF8, FGFR3, FGFR4, FLT4, FYN, GRB2, GRIN2A, NRG1, HSPB1, HSP90AA1, IL2RA, IL2RB, IL2RG, ITGAV, ITPR1, ITPR2, ITPR3, JUP, KDR, KIT, KRAS, MARK3, KITLG, NRAS, PEBP1, PDPK1, PGF, PIK3CB, PPP5C, PRKCA, PRKD1, PRKCZ, MAPK3, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPRA, RAC1, RAF1, RASA2, RPS27A, SHB, SHC1, SOS1, SPTA1, SPTB, UBB, VAV1, FGF23, CUL3, PEA15, NRP2, PSMF1, BCAR1, RAPGEF2, ELMO1, PSMD6, RBX1, ABI1, AKAP9, RASA4, WASF2, PSME3, VAV3, BAIAP2, FRS3 |
916 | GO:0050900 | 0.00 | 4.03 | 25.20 | 45 | 61 | leukocyte migration | ADA, ADORA1, ANGPT1, ANGPT2, ATP1B3, BSG, CD2, CD44, CD48, CD58, COL1A1, DBH, FYN, B4GALT1, GRB2, GRB7, HCK, ITGA6, ITGA3, ITGA5, ITGAL, ITGAM, ITGAV, ITGAX, ITGB1, KRAS, NRAS, OLR1, PIK3CB, PROC, PROS1, PTPN6, SELL, SELPLG, SHC1, SLC16A1, SOS1, SPN, STAT5B, SLC7A5, EPX, CD84, DOK2, PROCR, SLC7A9 |
917 | GO:0010332 | 0.00 | 4.03 | 12.94 | 23 | 31 | response to gamma radiation | ATM, ATR, BAX, BCL2, BCL2L1, BRCA2, CRYAB, CYBA, ELK1, ERCC6, FANCD2, GATA3, GPX1, IL1B, MEN1, PRKAA1, RAD51, TP73, WRN, XRCC2, TP63, SOCS3, CHEK2 |
918 | GO:0071398 | 0.00 | 4.03 | 12.94 | 23 | 31 | cellular response to fatty acid | ADCY6, ASS1, CCNB1, CPS1, GNAS, GNB1, FFAR3, HMGCS2, TNC, IL1B, P2RY4, P2RY6, PDK4, PRKAA1, PRKCE, PTAFR, PTGDR, PTGER4, SREBF1, TNFSF4, AKR1C3, ADAMTS1, NR1H4 |
919 | GO:0008217 | 0.00 | 4.03 | 20.80 | 37 | 50 | regulation of blood pressure | ACTA2, ACVRL1, ANPEP, ATP1A2, AVPR1B, BRS3, CACNA1B, CPA3, CTSG, CTSZ, CYP11B1, ACE, EDN2, EDN3, EDNRA, EDNRB, EMP2, ENPEP, F2R, F2RL1, GAS6, GCGR, NRG1, P2RX4, PCSK5, PTGS1, RPS6KA2, ACSM3, SGK1, SLC2A5, SOD1, TAC1, TNNI3, CYP4F2, ATP6AP2, RAMP2, CORIN |
920 | GO:0019724 | 0.00 | 4.02 | 11.24 | 20 | 27 | B cell mediated immunity | BCL3, C1QBP, SERPING1, C1QA, C1QB, C1QC, C1S, C5, C8B, CD74, CLU, CR2, CD55, ERCC1, CD46, ZP3, BCL10, RNF8, EXO1, BATF |
921 | GO:0046148 | 0.00 | 4.01 | 11.26 | 20 | 27 | pigment biosynthetic process | ALAD, ALAS1, ALAS2, ASIP, TSPO, CDH3, COX15, CPOX, CTNS, FECH, HMBS, CITED1, SLC11A2, SOX2, TRPC1, TYRP1, UROS, AP3D1, RAPGEF2, ZEB2 |
922 | GO:0031663 | 0.00 | 4.01 | 11.27 | 20 | 27 | lipopolysaccharide-mediated signaling pathway | PRDM1, BMP6, CD6, CD14, SCARB1, CD55, HCK, IL1B, IL18, IRAK1, IRAK2, LTF, CD180, PRKCA, PRKCE, MAPK3, PTAFR, TNFAIP3, RIPK2, TRIB1 |
923 | GO:0042130 | 0.00 | 4.01 | 11.27 | 20 | 27 | negative regulation of T cell proliferation | BMP4, CBLB, CDKN2A, DLG1, ERBB2, IHH, IL2RA, IL10, IDO1, PAWR, PRKAR1A, PTPN6, XCL1, SFTPD, SHH, SPN, SCGB1A1, PDE5A, GLMN, VSIG4 |
924 | GO:0051851 | 0.00 | 4.01 | 11.27 | 20 | 27 | modification by host of symbiont morphology or physiology | APCS, AQP1, CAV2, CHD1, CTSG, EP300, STOM, F2RL1, HPN, JUN, LTF, PARK2, PPIB, REST, SMARCA4, SP1, VAPB, VAPA, RAB9A, TUSC2 |
925 | GO:0055081 | 0.00 | 4.01 | 11.27 | 20 | 27 | anion homeostasis | ABCA1, APOA1, CACNA1A, CETP, CPS1, FGFR4, GOT1, INS, OTC, ENPP1, PRKAA1, SFRP4, SLC34A1, FGF23, DGAT1, XPR1, SLC9A3R1, LIPG, ABCG1, SLC34A2 |
926 | GO:0072080 | 0.00 | 4.00 | 20.87 | 37 | 50 | nephron tubule development | ACAT1, AGTR2, AQP1, BCL2, BMP4, CD44, DLG1, EYA1, FGF1, FGF8, FOXD1, GATA3, GDNF, GPC3, HOXD11, HES1, ILK, LAMA5, TACSTD2, CITED1, PAX2, PBX1, PGF, PSPN, PTCH1, SALL1, SHH, SIX1, SOX9, VEGFA, WNT1, WNT11, WNT2B, PAX8, DCHS1, PROM1, SIX2 |
927 | GO:0044409 | 0.00 | 4.00 | 28.80 | 51 | 69 | entry into host | ADRBK1, ANPEP, APCS, AXL, CAV2, CD4, CD80, CD86, SCARB1, SCARB2, CCR5, CR1, CR2, CXADR, CD55, DPP4, EFNB2, EPS15, FCN1, GAS6, GYPA, ICAM1, IDE, IFNA2, ITGA2, ITGA5, ITGAV, ITGB1, ITGB5, CD46, PVR, SERPINB3, SELPLG, SLAMF1, SLC10A1, SLC20A2, DYNLT1, TMPRSS2, TNFRSF4, TYRO3, UVRAG, TRIM25, FCN3, VAMP8, XPR1, IFITM3, TRIM38, SIVA1, IFITM2, WWP1, WWP2 |
928 | GO:0051806 | 0.00 | 4.00 | 28.80 | 51 | 69 | entry into cell of other organism involved in symbiotic interaction | ADRBK1, ANPEP, APCS, AXL, CAV2, CD4, CD80, CD86, SCARB1, SCARB2, CCR5, CR1, CR2, CXADR, CD55, DPP4, EFNB2, EPS15, FCN1, GAS6, GYPA, ICAM1, IDE, IFNA2, ITGA2, ITGA5, ITGAV, ITGB1, ITGB5, CD46, PVR, SERPINB3, SELPLG, SLAMF1, SLC10A1, SLC20A2, DYNLT1, TMPRSS2, TNFRSF4, TYRO3, UVRAG, TRIM25, FCN3, VAMP8, XPR1, IFITM3, TRIM38, SIVA1, IFITM2, WWP1, WWP2 |
929 | GO:0052192 | 0.00 | 4.00 | 28.80 | 51 | 69 | movement in environment of other organism involved in symbiotic interaction | ADRBK1, ANPEP, APCS, AXL, CAV2, CD4, CD80, CD86, SCARB1, SCARB2, CCR5, CR1, CR2, CXADR, CD55, DPP4, EFNB2, EPS15, FCN1, GAS6, GYPA, ICAM1, IDE, IFNA2, ITGA2, ITGA5, ITGAV, ITGB1, ITGB5, CD46, PVR, SERPINB3, SELPLG, SLAMF1, SLC10A1, SLC20A2, DYNLT1, TMPRSS2, TNFRSF4, TYRO3, UVRAG, TRIM25, FCN3, VAMP8, XPR1, IFITM3, TRIM38, SIVA1, IFITM2, WWP1, WWP2 |
930 | GO:0009408 | 0.00 | 3.99 | 9.57 | 17 | 23 | response to heat | CD14, DNMT1, EIF2B1, IGF1, IL1B, IL1R1, P2RX3, PRKCQ, SOD1, TRPV1, EIF2B4, EIF2B3, EIF2B2, EIF2B5, SOCS3, DNAJB4, PSIP1 |
931 | GO:0090257 | 0.00 | 3.99 | 7.85 | 14 | 19 | regulation of muscle system process | ADK, CAMK2G, CDK9, GTF2I, IGF1, IGFBP5, SLN, TRPC3, COL14A1, AKAP1, CTDP1, KLF4, AKAP6, AKAP13 |
932 | GO:0097192 | 0.00 | 3.98 | 9.58 | 17 | 23 | extrinsic apoptotic signaling pathway in absence of ligand | BAD, BAX, BCL2A1, BOK, CASP9, DCC, EYA2, IGF1, ITGAV, KITLG, PPP1CA, PPP2R1A, PPP2R1B, SRPX, BAG3, BCL2L10, BCL2L11 |
933 | GO:0006415 | 0.00 | 3.98 | 27.13 | 48 | 65 | translational termination | EIF5A, FAU, RPL10A, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, RPL14, RPL23, RPL35 |
934 | GO:0071333 | 0.00 | 3.98 | 27.13 | 48 | 65 | cellular response to glucose stimulus | BAD, CACNA1E, CFTR, CYBA, EFNA5, SLC29A1, EPHA5, ERN1, GAS6, GATA4, GCG, GHRHR, GPLD1, GPR27, HIF1A, HMGCR, FOXA2, ICAM1, IGF1, IGF1R, IL1B, IL1R1, KCNJ11, MEN1, OXCT1, PAX2, CDK16, SERPINF1, PRKACA, PRKCE, PTGER4, PTPRN, PTPRN2, RAF1, RAP1A, SMARCA4, SOX4, SRF, STAR, VSNL1, OGT, RAB11B, HMGN3, NRXN1, NR1D1, C2CD2L, NR1H4, GJB6 |
935 | GO:0007267 | 0.00 | 3.98 | 105.58 | 188 | 260 | cell-cell signaling | ACVR2B, ADAM10, ADORA2A, ADRA1B, ADRA2C, AGTR2, SLC25A4, ANXA1, ANXA5, AQP1, AREG, ARL2, ARNTL, ASIP, AVP, BAD, BLK, BMP4, BMP6, BST2, C1QA, CD80, CD86, TNFSF8, SIGLEC6, CD70, ADGRE5, CDC42, CFTR, CGA, CCR1, CCR5, CRY1, CTF1, CTGF, EDN3, EFNA1, EFNA3, EFNA4, EFNA5, EFNB2, ENPEP, ENSA, EPHA5, EREG, FGA, FGF3, FGF6, FGF9, FGF11, FGFR3, FGG, NR5A1, GALR1, GATA3, GATA4, GCG, GDF9, GHRH, GHRHR, GHSR, GJA3, GJA4, GJB1, GJB2, GLP1R, GLUD1, GNAS, GPLD1, GPR27, FFAR1, FFAR3, GRB2, GUCA1B, HIF1A, HMGCR, FOXA2, HES1, IAPP, IFNA2, IHH, IK, IL1B, IL1RN, IL10, IL13, IL18, INHA, INS, INSL3, INSL4, ISL1, ITPR1, ITPR2, NTF4, OXCT1, P2RY1, PCSK1, PCSK5, CDK16, PDE3B, PDE4C, PFKFB2, PGF, PGR, PHEX, PRKACA, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PYY, PTGS1, PTHLH, PTPRN, RAB1A, REST, RFX3, S100A9, SERPINB3, CCL20, CCL21, CCL22, CCL24, CXCL6, CXCL5, XCL1, SHH, SLC2A2, SLC16A1, SOX4, SOX11, SREBF1, SSTR2, SSTR3, STXBP3, HNF1A, KLF10, TMF1, TNFAIP6, TRH, TRPM2, TSHB, VIP, VIPR2, VSNL1, WNT1, WNT2, PAX8, SEMA3B, FGF23, FZD4, LTBP4, NR0B2, TNFSF11, TP63, VAMP8, TNFSF10, TNFSF9, IQGAP1, WISP3, WISP1, ARHGEF7, TNFSF18, SYT7, RAB11B, GPR50, HMGN3, EIF2AK3, STXBP5L, GDF15, CXCL14, NR1D1, CLOCK, SPCS2, C2CD2L, NR1H4, FGFBP1, CHST4, RAPGEF3, SEMA4F, CXCL13, GRAP, RAPGEF4, CAPN10, NUDT3, TUSC2 |
936 | GO:0042593 | 0.00 | 3.98 | 47.58 | 84 | 114 | glucose homeostasis | ADRA1B, BAD, CACNA1E, CAV3, CFTR, CNR1, CRY1, CRY2, CYBA, CYP11B1, DBH, DHPS, EFNA5, SLC29A1, EPHA5, ERN1, FGFR4, G6PC, SLC37A4, GAS6, GATA4, GCG, GCGR, GHRHR, GK, GPLD1, GPR27, FFAR1, HIF1A, HK2, HMGCR, FOXA2, ICAM1, IGF1, IGF1R, IGFBP5, IL1B, IL1R1, INS, KCNJ11, MEN1, OAS1, OXCT1, PAX2, PCK1, CDK16, PDE3B, PDK4, SERPINF1, PRCP, PRKAA1, PRKACA, PRKCE, PTCH1, PTGER4, PTPRN, PTPRN2, PYGL, RAF1, RANBP2, RAP1A, RPS6, SLC2A4, SLC16A1, SMARCA4, SOX4, SRF, STAR, STAT3, STK11, HNF1A, USF1, VSNL1, WFS1, OGT, RAB11B, HMGN3, NRXN1, STXBP5L, NR1D1, CARTPT, C2CD2L, NR1H4, GJB6 |
937 | GO:0006284 | 0.00 | 3.97 | 9.60 | 17 | 23 | base-excision repair | ERCC6, FEN1, HMGA1, NTHL1, OGG1, RFC1, RFC2, RFC3, RFC4, RFC5, RPA3, UNG, WRN, PARG, MBD4, PARP2, CCNO |
938 | GO:0071277 | 0.00 | 3.97 | 9.60 | 17 | 23 | cellular response to calcium ion | ADCY1, DPEP1, ECT2, GPLD1, GUCA1A, JUN, JUNB, JUND, RYR3, SCN5A, SYT1, AKR1C3, IQGAP1, CPNE1, CPNE6, RASA4, RASGRP2 |
939 | GO:1901862 | 0.00 | 3.97 | 9.60 | 17 | 23 | negative regulation of muscle tissue development | BMP4, CAV3, CXADR, TSC22D3, FGF3, FGF8, IGFBP5, KCNK2, NRAS, S100B, SHH, TP73, TWIST1, HDAC3, USP2, CTDP1, USP19 |
940 | GO:0002824 | 0.00 | 3.96 | 17.53 | 31 | 42 | positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | ADA, ANXA1, C3, CD4, CD28, CD80, CD40, FCER1A, FCER1G, FCER2, HLX, HPX, IFNG, IL1B, P2RX7, PRKCQ, PRKCZ, PVR, XCL1, SLC11A1, TRAF2, TNFSF4, UNG, WHSC1, ZP3, FZD5, TNFSF13, RIPK2, IL27RA, TNFSF13B, MALT1 |
941 | GO:0002573 | 0.00 | 3.95 | 7.89 | 14 | 19 | myeloid leukocyte differentiation | BMP4, CASP10, CDC42, CEBPE, F2RL1, GATA3, HHEX, IFI16, KIT, PDE1B, SP3, VEGFA, PIR, TSPAN2 |
942 | GO:0072522 | 0.00 | 3.93 | 34.56 | 61 | 83 | purine-containing compound biosynthetic process | ABCA1, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADCYAP1R1, ADORA2A, ADRB2, AMPD1, AMPD2, APLP1, AQP1, AVP, AVPR2, CALCR, CALM3, LPAR1, EDNRA, EDNRB, FSHR, GALR1, GCG, GHRH, GHRHR, GLP1R, GNAI3, GNAL, GNAS, GRM8, GUCA1A, GUCA1B, GUCA2A, GUCA2B, GUCY1B3, GUCY2C, GUCY2F, GUCY2D, HTR2C, INSL3, NTRK1, NTRK2, OAS1, OAS2, P2RY11, PRKCA, PTGER4, PTHLH, RAF1, RCVRN, UCN, VIP, VIPR2, WFS1, AKAP6, GABBR2, GUCA1C, CALCRL, RAMP2, CAP2, CAP1 |
943 | GO:0006635 | 0.00 | 3.93 | 7.91 | 14 | 19 | fatty acid beta-oxidation | AKT2, CNR1, CPT1B, CPT2, DECR1, ECH1, EHHADH, HADHA, PCCA, ABCD3, TWIST1, ECI2, SLC25A17, SLC27A2 |
944 | GO:0002702 | 0.00 | 3.93 | 7.92 | 14 | 19 | positive regulation of production of molecular mediator of immune response | CD36, CD74, F2RL1, FCER1G, FFAR3, PGC, PRKCZ, KLK7, TRAF2, FZD5, SEMA7A, BCL10, SPON2, MALT1 |
945 | GO:0033273 | 0.00 | 3.93 | 14.12 | 25 | 34 | response to vitamin | ATP2B1, BGLAP, TSPO, CD4, CDKN2D, CYP24A1, CYP27B1, F7, GAS6, HLCS, HMBS, TNC, ITGB1, OTC, PENK, PIM1, PTN, SNAI2, STC1, VDR, FGF23, TRIM24, KYNU, ADAMTS1, SETDB1 |
946 | GO:0060443 | 0.00 | 3.93 | 7.92 | 14 | 19 | mammary gland morphogenesis | AREG, BMP4, CAV3, EPHA2, ESR1, ETV4, ETV5, PGR, PTCH1, PTHLH, SLC12A2, SLIT2, NRG3, PHB2 |
947 | GO:0051591 | 0.00 | 3.93 | 14.13 | 25 | 34 | response to cAMP | AGXT, ALDH3A1, ALDOB, AREG, ATP7B, BSG, CDO1, COL1A1, DUSP1, HMGCS2, JUN, JUNB, JUND, LDHA, CITED1, OXT, PDE3A, PER1, PTPRN, PYGM, SDC1, SPARC, SREBF1, FOSL1, CARM1 |
948 | GO:0008209 | 0.00 | 3.92 | 7.93 | 14 | 19 | androgen metabolic process | SCARB1, AKR1C4, CYP3A4, ESR1, HSD17B3, HSD17B4, SHH, SRD5A1, STAR, UGT2B7, HSD17B6, AKR1C3, SGPL1, DHRS9 |
949 | GO:0009261 | 0.00 | 3.92 | 7.93 | 14 | 19 | ribonucleotide catabolic process | HPRT1, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, PDE5A, ENTPD4, RAPGEF3, PDE10A |
950 | GO:0042982 | 0.00 | 3.92 | 7.93 | 14 | 19 | amyloid precursor protein metabolic process | ACHE, CLU, DHCR24, DLG1, FLOT2, PAWR, KLK6, SORL1, PICALM, HAP1, ABCG1, ABCA7, OLFM1, TMED10 |
951 | GO:0045824 | 0.00 | 3.92 | 7.93 | 14 | 19 | negative regulation of innate immune response | A2M, ADAR, SERPING1, CR1, IFI16, IGF2, INS, SERPINB9, RPS19, SERPINB4, TNFAIP3, TYRO3, NR1H2, TRAFD1 |
952 | GO:0045932 | 0.00 | 3.92 | 7.93 | 14 | 19 | negative regulation of muscle contraction | ADORA1, ADRA2C, ADRB2, ADRBK1, ATP1A2, ATP2A1, PIK3CG, PRKG1, PTGER4, RGS2, SOD1, TNNT1, PDE5A, CALCRL |
953 | GO:0048873 | 0.00 | 3.92 | 7.93 | 14 | 19 | homeostasis of number of cells within a tissue | ADD1, BAX, BCL2, CD7, F2R, FLT3, KRAS, LIPA, P2RX7, RAC1, RAC3, SOX9, COL14A1, CORO1A |
954 | GO:0060795 | 0.00 | 3.92 | 7.93 | 14 | 19 | cell fate commitment involved in formation of primary germ layer | BMP4, BMPR1A, ETS2, ETV2, EYA1, EYA2, GATA6, SMAD1, PAX2, SOX2, EOMES, FZD7, KLF4, SIX2 |
955 | GO:1901985 | 0.00 | 3.92 | 7.93 | 14 | 19 | positive regulation of protein acetylation | BRCA1, KAT2A, IL1B, ISL1, MAPK3, SNAI2, SOX4, CAMK1, KAT2B, RPS6KA4, RPS6KA5, RAPGEF3, RUVBL2, ARID5A |
956 | GO:1903959 | 0.00 | 3.92 | 7.93 | 14 | 19 | regulation of anion transmembrane transport | AKT2, CFTR, CLCN2, CLCN3, CLCN5, CLCN6, CLCN7, CLCNKA, CLCNKB, GRK6, PTAFR, SLC34A1, VDAC2, RIPK1 |
957 | GO:2000352 | 0.00 | 3.92 | 7.93 | 14 | 19 | negative regulation of endothelial cell apoptotic process | ABL2, ANGPT1, KRIT1, FGA, FGG, GAS6, GATA3, ICAM1, IL13, KDR, SERPINE1, TNFAIP3, SCG2, RAMP2 |
958 | GO:2001259 | 0.00 | 3.92 | 7.93 | 14 | 19 | positive regulation of cation channel activity | BMP4, CALM3, CTSS, GSTM2, KCNJ11, NTSR1, S100A1, HAP1, GSTO1, AKAP7, AKAP6, KCNE2, KCNE3, TRDN |
959 | GO:0008584 | 0.00 | 3.91 | 20.39 | 36 | 49 | male gonad development | ACVR2A, AMHR2, BAX, BCL2, BCL2L1, BIK, BOK, COL9A3, CTNNA1, ERCC1, FANCA, FGF9, FSHR, GATA3, GATA6, HMGCS1, ING2, INHA, INSL3, KIT, MEA1, KITLG, PRKACG, RRM1, SRD5A1, STAR, UBB, WNT2B, CSDE1, UTF1, AKR1C3, ADAM15, EIF2S2, BCL2L11, FSTL3, PRDX4 |
960 | GO:0019933 | 0.00 | 3.90 | 14.18 | 25 | 34 | cAMP-mediated signaling | ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADCYAP1R1, DGKQ, EIF4EBP2, EPHA5, GHRH, GHRHR, GLP1R, GNAI1, PDE3A, PDE3B, PDE4A, PDE4D, PDE7A, RGS2, SOX9, AKAP6, RIMS2, RAPGEF3, PDE10A, RAPGEF4 |
961 | GO:0007422 | 0.00 | 3.90 | 14.19 | 25 | 34 | peripheral nervous system development | AKT2, ALDH3A2, ADGRB2, CDK5, EDNRB, EGR2, EGR3, ERBB2, ETV1, GDNF, GPC1, NRG1, ILK, ISL1, NTF3, NTRK2, SERPINI1, SCN8A, SLC5A3, SOD1, SOX10, TBCE, UGT8, HAND2, ONECUT2 |
962 | GO:0055078 | 0.00 | 3.90 | 14.19 | 25 | 34 | sodium ion homeostasis | ADORA1, AGTR2, ANPEP, ATP1A2, ATP12A, ATP1B3, ATP4A, AVP, AVPR2, COMT, EDNRB, KNG1, OXT, PTGER4, SCNN1A, SCNN1B, SCNN1G, SGK1, SLC8A1, SLC9A1, TAC1, UPK3A, CYP4F2, SGK2, CORIN |
963 | GO:0007498 | 0.00 | 3.90 | 26.71 | 47 | 64 | mesoderm development | ACVR1, ACVR2A, ACVR2B, BMP4, BMPR1A, BMPR2, BMX, BTK, EPHA2, ETS2, ETV2, EXT1, EXT2, EYA1, EYA2, FGF8, HCK, ITGA2, ITGA3, ITGB1, ITGB4, SMAD1, SMAD3, OVOL1, PAX2, PRKAR1A, RPL38, SHH, SNAI1, SRF, T, TAL1, TSPY1, KDM6A, VEGFA, WNT11, ZIC2, EOMES, ITGA8, TP63, CHRD, KLF4, CER1, HAND1, IKZF1, CITED2, SIX2 |
964 | GO:0097306 | 0.01 | 3.89 | 6.22 | 11 | 15 | cellular response to alcohol | ABCA1, KLF9, ELK1, GPLD1, HMGCS1, PTAFR, PTCH1, RAD51, LRP8, KLF4, KLF2 |
965 | GO:0016032 | 0.00 | 3.89 | 85.38 | 151 | 209 | viral process | AP2A1, AP2B1, AP1G1, AMBP, BIN1, SLC25A4, ARF1, BAX, BICD1, BNIP3, BNIP3L, BUB1, C1QBP, CAMLG, CASP8, CCNT2, CDC25C, CENPA, AP2M1, AP1S1, AP2S1, CCR3, COPB1, CX3CR1, DDX11, DLG1, DMBT1, DYNC1I2, E4F1, EPHA2, EIF4A1, EIF4A2, EIF4E, EIF4G1, FCGR2B, FDPS, FYN, KAT2A, GFI1, GRB2, HCK, HPX, HSPA8, SP110, IL2RB, IL2RG, KDR, KLC1, TNPO1, IPO5, KRT7, KRT18, KRT19, MAP3K5, MFGE8, MAPK3, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RAB6A, RAC1, RALA, RB1, RBL1, ABCE1, SATB1, SET, SGTA, SHC1, SKP1, STAT2, STAT3, SUV39H1, SYK, TAF2, TAF4B, TAF5, TAF6, TAF13, TBP, TSPAN7, TNFRSF1A, TOP1, TP73, TSC2, UBE3A, SUMO1, UNG, VIM, EIF4H, CUL5, CUL4A, CUL2, CUL1, IKBKG, CDK13, DYNLL1, BECN1, RNGTT, CFLAR, KAT2B, AP1S2, AP1M1, CLDN6, PSMF1, KDM4A, VPRBP, CUL7, ELMO1, PSMD6, RBX1, ACOT8, ABI1, AP1M2, RAD50, ABI2, WASF2, PSME3, TRIM22, NXF1, CARM1, RBCK1, IVNS1ABP, ZMYND11, SRCAP, COPS6, SF3B2, ATF7 |
966 | GO:0043401 | 0.00 | 3.89 | 37.56 | 66 | 90 | steroid hormone mediated signaling pathway | NR0B1, ARNTL, BMP4, BRCA1, CCNE1, CRY1, CRY2, DAB2, DDX5, DEFA1, EP300, ESR1, ESRRG, NR5A1, NR6A1, GHRHR, NR4A1, HNF4G, PRMT2, IGF1, ISL1, SCGB2A1, CNOT2, PER1, PGR, PHB, PPP5C, RAN, RARA, RARB, RB1, RNF6, RXRA, RXRG, SAFB, SGK1, SKP2, SMARCA4, TAF7, NR2F1, NR2F2, NR2E1, NR2C1, NR2C2, UBE3A, NR1H2, VDR, YWHAH, NRIP1, NR0B2, NR1I2, BUD31, RQCD1, TRIP4, NR1D1, CLOCK, NR1I3, NR1H4, NR1D2, NR2E3, HDAC6, PGRMC2, RBM14, CARM1, AKAP13, PHB2 |
967 | GO:0001666 | 0.00 | 3.89 | 34.04 | 60 | 82 | response to hypoxia | ABAT, ACTN4, ADA, ADORA1, ADSL, ALAD, ALAS2, ALDH3A1, ANG, ANGPT2, ASCL2, ATM, CAT, CD38, CHRNB2, CLDN3, CRYAB, DNMT3B, DPP4, EDNRA, ERCC3, ETS1, FLT1, HMBS, IGF1, IL1B, ITGA2, ITPR1, ITPR2, KCNA5, LDHA, SMAD3, SLC11A2, NRF1, P2RX3, PAM, PENK, PGF, PRKCB, PRKCQ, PYGM, RAF1, RYR1, RYR2, SCNN1B, CX3CL1, SDC2, SHC1, SLC6A4, SRF, STAT5B, TRH, TSC2, USF1, BECN1, SOCS3, PDLIM1, RAMP2, TACC3, GPR182 |
968 | GO:0002526 | 0.00 | 3.89 | 12.46 | 22 | 30 | acute inflammatory response | A2M, ACVR1, ADORA1, C1QBP, SERPING1, C5, C8B, CD59, CR1, CD55, F3, B4GALT1, CD46, OGG1, CFP, PHB, PRCP, PROS1, S100A8, TNFSF4, VTN, VNN1 |
969 | GO:0030814 | 0.00 | 3.87 | 25.04 | 44 | 60 | regulation of cAMP metabolic process | ABCA1, ADCY7, ADCYAP1R1, ADORA2A, ADRB2, APLP1, AVP, AVPR2, CALCR, CALM3, LPAR1, EDNRA, EDNRB, FSHR, GALR1, GCG, GHRH, GHRHR, GLP1R, GNAI3, GNAL, GNAS, GRM8, INSL3, NTRK1, NTRK2, P2RY11, PDE4D, PF4, PRKCA, PTGER4, PTHLH, RAF1, UCN, VIP, VIPR2, WFS1, AKAP6, GABBR2, CALCRL, RAMP2, RAPGEF3, CAP2, CAP1 |
970 | GO:0007204 | 0.00 | 3.87 | 49.61 | 87 | 119 | positive regulation of cytosolic calcium ion concentration | ABL2, ADCYAP1R1, ADRA1B, ATP1A2, AVP, AVPR1B, BAX, BCL2, BDKRB2, BMP4, CACNA1A, CALCR, CALM3, CASQ2, CAV3, CD4, CD36, CD38, CD52, CCR1, CCR3, CCR5, CCR8, CYBA, CD55, DIAPH1, S1PR3, EDN2, EDNRB, ESR1, F2RL1, GALR1, GLP1R, GNA15, GNAT2, GNB1, CCR10, XCR1, GSTM2, HRC, IL1B, IL13, ITPR1, ITPR2, ITPR3, KNG1, NTSR1, OXT, P2RX3, P2RX4, P2RX7, P2RY1, P2RY2, P2RY4, PDE4D, PDPK1, PIK3CG, PLN, PRKACA, PRKCE, PRKD1, PTH1R, PTPN6, RYR1, RYR2, RYR3, CCL21, XCL1, SLC8A1, SLC8A3, SNCA, TAC1, TRPC1, TRPC3, TRPM2, TRPV1, S1PR4, HAP1, GSTO1, AKAP6, ATG5, TRDN, CIB2, CHERP, CXCL13, CCR9, CORO1A |
971 | GO:1901655 | 0.01 | 3.87 | 6.24 | 11 | 15 | cellular response to ketone | ADCY1, ADCY3, ATP2B1, KLF9, CDC5L, ELK1, GAS6, GNAI1, AIFM1, KLF4, KLF2 |
972 | GO:0038096 | 0.00 | 3.86 | 18.78 | 33 | 45 | Fc-gamma receptor signaling pathway involved in phagocytosis | ACTB, ACTG1, CD3G, CDC42, FCGR2A, FGR, FYN, GRB2, HCK, HSP90AA1, HSP90AB1, ITPR1, ITPR2, ITPR3, LIMK1, PIK3CB, PRKCE, MAPK3, RAC1, SYK, VAV1, ELMO1, ABI1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, WASF2, VAV3, BAIAP2, ARPC1A |
973 | GO:0051149 | 0.00 | 3.86 | 12.51 | 22 | 30 | positive regulation of muscle cell differentiation | BCL2, BMP4, BNIP2, CAV3, CD53, CDC42, CDH15, CTH, CTNNA1, CTNNA2, EFNB2, NRG1, RBPJ, NTN3, PROX1, RBM4, SHH, SMARCD3, CAMK1, AKAP6, GDF15, EHD1 |
974 | GO:0048608 | 0.00 | 3.86 | 37.99 | 67 | 92 | reproductive structure development | ACVR2A, NR0B1, AMHR2, ATRX, AXL, CCND1, BIK, BMP6, BOK, BRCA2, COL9A3, DHCR24, DLG1, ERCC1, FANCA, FGF8, FGF9, NR5A1, GATA3, GATA4, GATA6, GDF9, HSD17B10, HMGCS1, HSD17B3, HSD17B4, IDH1, ING2, INSL3, MEA1, NTRK1, PGR, PRKACG, PTPRN, RAB13, ARID4A, RRM1, SALL1, SDC1, SLIT3, SOX2, SRD5A1, SRY, STAR, STAT5B, TMF1, TSPY1, TYRO3, UBB, WNT2B, CSDE1, NRIP1, FZD4, UTF1, AKR1C3, ADAM15, SGPL1, EIF2S2, SLIT2, ADAMTS1, BCL2L11, AKAP9, IRX5, FSTL3, CITED2, SEMA3A, PRDX4 |
975 | GO:0045453 | 0.01 | 3.86 | 6.25 | 11 | 15 | bone resorption | ACP5, ADRB2, TPP1, CTSK, IHH, PTH1R, RAC1, RAC2, RAB7A, GPR55, RAB3D |
976 | GO:0008542 | 0.00 | 3.86 | 12.52 | 22 | 30 | visual learning | ABL2, ADRA1B, ATP1A2, CACNA1E, CDK5, CHRNB2, CTNS, DBH, GRIN2A, HIF1A, HMGCR, HRH1, HRH2, ITGB1, KIT, KRAS, NTS, PDE1B, PTPRZ1, SGK1, DEAF1, RGS14 |
977 | GO:0032007 | 0.01 | 3.85 | 6.26 | 11 | 15 | negative regulation of TOR signaling | ARNTL, ATM, CRYBA1, HIF1A, PRKAA1, STK11, TSC1, TSC2, EPM2A, MAPKAPK5, PDCD6 |
978 | GO:0033539 | 0.01 | 3.85 | 6.26 | 11 | 15 | fatty acid beta-oxidation using acyl-CoA dehydrogenase | ACADL, ACADM, ACADS, ACADSB, ACADVL, ACOX1, ETFA, ETFDH, IVD, ACOX2, ACOX3 |
979 | GO:0050873 | 0.01 | 3.85 | 6.26 | 11 | 15 | brown fat cell differentiation | ADRB2, BNIP3, INS, ITGA6, ALDH6A1, RGS2, SLC2A4, UCP1, PEX11A, ZNF516, ARL4A |
980 | GO:0051894 | 0.01 | 3.85 | 6.26 | 11 | 15 | positive regulation of focal adhesion assembly | COL16A1, HRG, KDR, SMAD3, PTPRJ, RAC1, S100A10, SDC4, TSC1, VEGFA, ITGB1BP1 |
981 | GO:0060669 | 0.01 | 3.85 | 6.26 | 11 | 15 | embryonic placenta morphogenesis | GJB5, GRB2, IL10, ITGA4, LLGL2, SPINT1, ST14, FZD5, SOCS3, TRIM28, SPINT2 |
982 | GO:0071470 | 0.01 | 3.85 | 6.26 | 11 | 15 | cellular response to osmotic stress | AQP1, BDKRB2, TSPO, DDX3X, SERPINB6, RELB, SLC2A4, SLC6A12, SLC12A1, ARHGEF2, OXSR1 |
983 | GO:0072132 | 0.01 | 3.85 | 6.26 | 11 | 15 | mesenchyme morphogenesis | ACTA2, BMPR1A, FGF8, RBPJ, ISL1, SMAD3, SNAI2, SOX9, TWIST1, WNT11, DCHS1 |
984 | GO:0086005 | 0.01 | 3.85 | 6.26 | 11 | 15 | ventricular cardiac muscle cell action potential | CAV3, DSC2, DSP, GJA5, JUP, KCNE1, KCNQ1, RYR2, SCN5A, SNTA1, KCNE2 |
985 | GO:0071326 | 0.00 | 3.84 | 27.96 | 49 | 67 | cellular response to monosaccharide stimulus | BAD, CACNA1E, CFTR, CYBA, EFNA5, SLC29A1, EPHA5, ERN1, GAS6, GATA4, GCG, GHRHR, GPLD1, GPR27, HIF1A, HMGCR, FOXA2, ICAM1, IGF1, IGF1R, IL1B, IL1R1, KCNJ11, MEN1, OXCT1, PAX2, CDK16, SERPINF1, PRKACA, PRKCE, PTGER4, PTPRN, PTPRN2, RAF1, RAP1A, SLC2A5, SMARCA4, SOX4, SRF, STAR, VSNL1, OGT, RAB11B, HMGN3, NRXN1, NR1D1, C2CD2L, NR1H4, GJB6 |
986 | GO:0019083 | 0.00 | 3.82 | 35.41 | 62 | 85 | viral transcription | FAU, RPL10A, NUP88, NUP98, RANBP2, REST, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, SP100, TARBP2, USF1, USF2, NUP214, AAAS, RPL14, RPL23, NUP155, NUP93, IFITM3, NUP50, NUPL2, RPL35 |
987 | GO:0052652 | 0.00 | 3.82 | 26.25 | 46 | 63 | cyclic purine nucleotide metabolic process | ABCA1, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADCYAP1R1, ADORA2A, ADRB2, AMPD2, APLP1, AVP, AVPR2, CALCR, CALM3, LPAR1, EDNRA, EDNRB, FSHR, GALR1, GCG, GHRH, GHRHR, GLP1R, GNAI3, GNAL, GNAS, GRM8, INSL3, NTRK1, NTRK2, P2RY11, PRKCA, PTGER4, PTHLH, RAF1, UCN, VIP, VIPR2, WFS1, AKAP6, GABBR2, CALCRL, RAMP2, CAP2, CAP1 |
988 | GO:0071156 | 0.00 | 3.82 | 26.27 | 46 | 63 | regulation of cell cycle arrest | AKT2, BIN1, ATM, BRCA1, CDK5, CDKN1A, CDKN2A, FAP, GATA6, FOXO4, PRKACA, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SOX4, TP73, UBB, RNF112, CRADD, PSMF1, PSMD6, PSME3 |
989 | GO:0048709 | 0.00 | 3.82 | 10.83 | 19 | 26 | oligodendrocyte differentiation | BMP4, BOK, CDK5, CDKN2C, CNP, ERBB2, NRG1, HES1, NTRK2, PTPRJ, PTPRZ1, SLC8A3, SOX5, SOX9, SOX10, TRPC4, VTN, WDR1, TSPAN2 |
990 | GO:0002474 | 0.00 | 3.81 | 26.29 | 46 | 63 | antigen processing and presentation of peptide antigen via MHC class I | AZGP1, CD36, CTSS, CYBA, ACE, FCER1G, FCGR1B, ITGAV, ITGB5, ABCB1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, UBB, PSMF1, PSMD6, PSME3, SEC24B, IFI30, SEC23A, SEC24A, SEC61B |
991 | GO:0021762 | 0.00 | 3.80 | 10.85 | 19 | 26 | substantia nigra development | ACTB, ATP5F1, ATP5J, CALM3, CASP5, CDC42, CNP, COX6B1, FGF9, FGFR3, GLUD1, LDHA, RAD1, S100A1, YWHAH, ZNF148, DYNLL1, INA, SYNGR3 |
992 | GO:0032760 | 0.00 | 3.80 | 10.85 | 19 | 26 | positive regulation of tumor necrosis factor production | CD2, CD14, TNFRSF8, CD36, CLU, CYBA, FCER1G, HSPB1, IFNG, ISL1, PF4, PTAFR, SPN, TWIST1, RIPK1, RIPK2, ARHGEF2, SPON2, ARFGEF2 |
993 | GO:0060416 | 0.00 | 3.80 | 10.85 | 19 | 26 | response to growth hormone | ASS1, CISH, CPS1, CSH1, F7, GH2, HMGCS2, IGFBP5, MAPK3, PTPN1, PTPN6, RBBP4, SLC34A1, SRD5A1, STAR, STAT3, STAT5B, SOCS3, TRIM16 |
994 | GO:0072006 | 0.00 | 3.79 | 20.01 | 35 | 48 | nephron development | ACAT1, ACTA2, ANGPT1, ANGPT2, BCL2, CD44, COL4A3, COL4A4, DLG1, ENPEP, EYA1, FGF1, FGF8, FOXD1, GATA3, GPC3, HOXD11, ILK, ITGA3, LAMA5, TACSTD2, PBX1, PGF, PSPN, PTCH1, SHH, SIX1, VEGFA, WNT1, WNT11, WNT2B, DCHS1, SERPINB7, IQGAP1, PROM1 |
995 | GO:0007193 | 0.00 | 3.79 | 15.44 | 27 | 37 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADORA1, APLP1, CHRM1, CHRM3, CORT, S1PR1, LPAR1, S1PR3, FLNA, GNAI1, GNAI3, GNAL, GNAZ, FFAR3, GRIK3, GRM8, INSL3, P2RY1, RGS1, SSTR2, PTGDR2, HRH3 |
996 | GO:0070911 | 0.00 | 3.79 | 15.44 | 27 | 37 | global genome nucleotide-excision repair | CCNH, DDB1, DDB2, ERCC1, ERCC3, ERCC4, ERCC5, RFC1, RFC2, RFC3, RFC4, RFC5, RPA3, RPS27A, SUMO3, UBB, UBE2V2, SUMO1, XPA, XPC, CUL4B, CUL4A, COPS3, CHD1L, RBX1, COPS8, COPS6 |
997 | GO:0002790 | 0.00 | 3.76 | 11.96 | 21 | 29 | peptide secretion | ABCA1, ACVR2B, ANXA1, AQP1, CAMK2G, EDN3, IL1RN, PTPRN, PTPRN2, RAB1A, RAF1, STXBP3, TACR2, HNF1A, VIP, TRPV1, LTBP4, RAB11B, EIF2AK3, RIMS2, CPLX1 |
998 | GO:0010950 | 0.04 | 3.76 | 4.57 | 8 | 11 | positive regulation of endopeptidase activity | CR1, PSME1, PSME2, SERPINB3, SEMG1, PICALM, PSME3, ADRM1 |
999 | GO:0070848 | 0.02 | 3.75 | 5.61 | 10 | 14 | response to growth factor | ANXA3, EPHA2, TNC, IL1R1, LUM, P2RY1, P2RY2, SOX2, SCGB1A1, HDAC6 |
1000 | GO:0070482 | 0.00 | 3.75 | 36.09 | 63 | 87 | response to oxygen levels | ABAT, ACTN4, ADA, ADORA1, ADSL, ALAD, ALAS2, ALDH3A1, ANG, ANGPT2, ASCL2, ATM, CAT, CD38, CDK4, CDKN1A, CHRNB2, COL1A1, CLDN3, CRYAB, CTGF, DPP4, EDNRA, ERCC3, ETS1, FLT1, HMBS, IGF1, IL1B, ITGA2, ITPR1, ITPR2, KCNA5, LDHA, SMAD3, SLC11A2, NRF1, P2RX3, PAM, PENK, PGF, PRKCB, PRKCQ, PYGM, RAF1, RYR1, RYR2, SCNN1B, CX3CL1, SDC2, SHC1, SLC6A4, SRF, STAT5B, TRH, TSC2, USF1, BECN1, SOCS3, PDLIM1, RAMP2, TACC3, GPR182 |
1001 | GO:0051897 | 0.00 | 3.75 | 18.36 | 32 | 44 | positive regulation of protein kinase B signaling | ANGPT1, AXL, C1QBP, CD28, CHI3L1, HBEGF, F3, F7, F10, GAS6, GATA3, GPX1, HCLS1, NRG1, IGF1, IGF1R, IGF2, IGFBP5, ILK, INS, PIK3CG, PTPRJ, CCL21, ITSN1, VEGFB, ZP3, TNFSF11, AKR1C3, CPNE1, ITGB1BP1, BAG4, ARFGEF1 |
1002 | GO:0002088 | 0.00 | 3.75 | 9.17 | 16 | 22 | lens development in camera-type eye | BFSP1, CDK4, CRYAB, CRYBA1, CTNS, DLG1, GATA3, LIM2, SMAD3, NTRK3, TMOD1, VIM, WNT2, WNT2B, BFSP2, ZEB2 |
1003 | GO:0001822 | 0.00 | 3.74 | 28.64 | 50 | 69 | kidney development | ACVR2B, ALDH9A1, APC, ARG2, ASS1, BAX, BMP6, CA2, CAT, CENPF, CUX1, DCN, ACE, EFNB2, EPHA4, EPHA7, HAS2, HMGCS2, KCNJ8, EPCAM, SMAD1, SMAD3, SMAD6, SMAD7, ODC1, OVOL1, PCSK5, SERPINF1, PROX1, RARA, RARB, SDC1, SDC4, SLC12A1, SLC34A1, SOX11, TP73, TSC1, UPK3A, WFS1, IFT88, ALDH1A2, SGPL1, RGN, CRLF1, CER1, ADAMTS1, BCL2L11, FSTL3, TMED10 |
1004 | GO:0002275 | 0.00 | 3.74 | 9.17 | 16 | 22 | myeloid cell activation involved in immune response | F2RL1, FCER1A, FGR, IL13, KIT, PDPK1, PIK3CG, RAC2, S100A13, SLAMF1, LAT2, VAMP8, SNAP23, CD84, GAB2, CPLX2 |
1005 | GO:1901216 | 0.04 | 3.74 | 4.58 | 8 | 11 | positive regulation of neuron death | BAD, CLU, ELK1, MAP3K5, PTPRZ1, TRPM2, AIMP2, PICALM |
1006 | GO:0030195 | 0.04 | 3.74 | 4.58 | 8 | 11 | negative regulation of blood coagulation | ABAT, ADRB2, ALOX12, ANXA5, KNG1, PRKG1, PROC, VTN |
1007 | GO:0001836 | 0.00 | 3.74 | 9.17 | 16 | 22 | release of cytochrome c from mitochondria | BAD, BAX, BCL2, BCL2A1, BID, BIK, BNIP3, CCK, CLU, IFI6, SFN, JUN, SOD2, HRK, TNFSF10, BCL2L11 |
1008 | GO:0014812 | 0.00 | 3.74 | 13.77 | 24 | 33 | muscle cell migration | AAMP, ANXA1, BCL2, ACE, LPAR1, F3, HAS2, IGF1, IGFBP3, IGFBP5, ILK, ITGA2, P2RY2, P2RY6, SERPINE1, PTGER4, SIX1, SORL1, VTN, ITGB1BP1, SLIT2, HDAC4, TRIB1, RAPGEF3 |
1009 | GO:0032945 | 0.00 | 3.74 | 13.77 | 24 | 33 | negative regulation of mononuclear cell proliferation | ATM, PRDM1, BMP4, CBLB, CDKN2A, CTLA4, DLG1, ERBB2, IHH, IL2RA, IL10, IDO1, PAWR, PRKAR1A, PTPN6, XCL1, SFTPD, SHH, SOX11, SPN, SCGB1A1, PDE5A, GLMN, VSIG4 |
1010 | GO:2000378 | 0.00 | 3.74 | 9.18 | 16 | 22 | negative regulation of reactive oxygen species metabolic process | ACP5, BCL2, BNIP3, BRCA1, TSPO, CRYAB, HIF1A, HK2, IL10, PARK2, PAX2, PTGIS, BECN1, RGN, ATG5, TRAP1 |
1011 | GO:0009653 | 0.00 | 3.74 | 15.44 | 28 | 40 | anatomical structure morphogenesis | AMHR2, BICD1, CST6, S1PR3, EYA4, EYA3, EZH1, F2R, GSC2, HPGD, FOXK2, KRT18, KRT35, PCSK5, PTPRJ, NR2F2, TP73, TPD52, TSHB, ZNF141, CLTCL1, QKI, SOX13, PTBP3, ATP6AP2, AGR2, IGF2BP3, RCAN3 |
1012 | GO:1901016 | 0.04 | 3.74 | 4.59 | 8 | 11 | regulation of potassium ion transmembrane transporter activity | ATP1B3, CASQ2, CAV3, DNM2, OXSR1, AKAP9, RAPGEF3, WWP2 |
1013 | GO:0014855 | 0.00 | 3.73 | 9.18 | 16 | 22 | striated muscle cell proliferation | ANGPT1, CCNB1, CXADR, GATA4, GATA6, NRG1, RBPJ, KCNK2, SMAD1, PRKAR1A, SHH, SIX1, STAT3, TP73, WNT2, CFLAR |
1014 | GO:0046461 | 0.00 | 3.73 | 9.18 | 16 | 22 | neutral lipid catabolic process | APOA1, APOA4, APOC2, APOH, DAGLA, CPS1, FABP2, FABP6, FABP7, GPLD1, LIPE, PIK3CG, PPP1CA, PRKACA, PRKACB, PRKACG |
1015 | GO:0090184 | 0.00 | 3.73 | 9.18 | 16 | 22 | positive regulation of kidney development | AGTR2, BMP4, EDNRA, FOXD1, GATA3, GDNF, PAX2, SALL1, SHH, SIX1, SOX9, VEGFA, WNT2B, PAX8, SERPINB7, PROM1 |
1016 | GO:1904377 | 0.00 | 3.73 | 9.18 | 16 | 22 | positive regulation of protein localization to cell periphery | ARF6, DLG1, EPHA2, ACSL3, IFNG, ITGA3, ITGB1, PDPK1, PRKCI, VIL1, EZR, NRXN1, RAMP3, AGR2, SORBS1, RER1 |
1017 | GO:0009084 | 0.04 | 3.73 | 4.59 | 8 | 11 | glutamine family amino acid biosynthetic process | GLS, GLUD1, GLUD2, GLUL, OAT, PYCR1, ALDH18A1, ALDH4A1 |
1018 | GO:0006309 | 0.04 | 3.73 | 4.59 | 8 | 11 | apoptotic DNA fragmentation | BAX, CDKN2A, DFFA, DFFB, DNASE1L3, KPNA1, KPNB1, AIFM1 |
1019 | GO:0007213 | 0.04 | 3.73 | 4.59 | 8 | 11 | G-protein coupled acetylcholine receptor signaling pathway | ADRBK1, CHRM1, CHRM3, GNA15, GNAQ, GNB1, RGS10, HRH3 |
1020 | GO:0010665 | 0.04 | 3.73 | 4.59 | 8 | 11 | regulation of cardiac muscle cell apoptotic process | BNIP3, CAMK2A, NRG1, HMGCR, ILK, PDPK1, HAND2, RAPGEF3 |
1021 | GO:0018298 | 0.04 | 3.73 | 4.59 | 8 | 11 | protein-chromophore linkage | AMBP, OPN1SW, CRY1, CRY2, OPN1MW, OPN1LW, RGR, RRH |
1022 | GO:0031268 | 0.04 | 3.73 | 4.59 | 8 | 11 | pseudopodium organization | APC, CDC42, F2RL1, KIT, CCL21, CDC42EP2, CDC42EP3, CDC42EP1 |
1023 | GO:0032462 | 0.04 | 3.73 | 4.59 | 8 | 11 | regulation of protein homooligomerization | BID, BIK, CLU, CLDN7, PEX14, PEX5, HRK, BCL2L11 |
1024 | GO:0034047 | 0.04 | 3.73 | 4.59 | 8 | 11 | regulation of protein phosphatase type 2A activity | ENSA, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, EIF2AK2, SET, ARPP19 |
1025 | GO:0036065 | 0.04 | 3.73 | 4.59 | 8 | 11 | fucosylation | FUT6, FUT8, CFP, SPON1, FUT9, ADAMTS13, ADAMTS5, ADAMTS7 |
1026 | GO:0036109 | 0.04 | 3.73 | 4.59 | 8 | 11 | alpha-linolenic acid metabolic process | ACAA1, ACOX1, ABCD1, ACSL1, HSD17B4, SCP2, FADS2, ACOT8 |
1027 | GO:0043576 | 0.04 | 3.73 | 4.59 | 8 | 11 | regulation of respiratory gaseous exchange | ADORA1, PHOX2A, ATP1A2, GLRA1, GLS, NTSR1, SLC5A3, PHOX2B |
1028 | GO:0055026 | 0.04 | 3.73 | 4.59 | 8 | 11 | negative regulation of cardiac muscle tissue development | CAV3, CXADR, FGF3, FGF8, KCNK2, TP73, HDAC3, CTDP1 |
1029 | GO:0060143 | 0.04 | 3.73 | 4.59 | 8 | 11 | positive regulation of syncytium formation by plasma membrane fusion | CD53, FLT3LG, CAMK1, TNFSF14, ADAM9, GDF15, RAPGEF3, EHD1 |
1030 | GO:0070242 | 0.04 | 3.73 | 4.59 | 8 | 11 | thymocyte apoptotic process | ADA, BAX, BMP4, CASP8, DFFA, HIF1A, RAG1, BCL2L11 |
1031 | GO:0070293 | 0.04 | 3.73 | 4.59 | 8 | 11 | renal absorption | AQP1, GAS6, HAS2, KCNQ1, SGK1, HNF1A, AKR1C3, SLC9A3R1 |
1032 | GO:0070498 | 0.04 | 3.73 | 4.59 | 8 | 11 | interleukin-1-mediated signaling pathway | IL1R1, IL1RN, IRAK1, IRAK2, MAPK3, IL1RL2, RPS6KA4, RPS6KA5 |
1033 | GO:0070875 | 0.04 | 3.73 | 4.59 | 8 | 11 | positive regulation of glycogen metabolic process | ADRA1B, AKT2, IGF1, IGF2, INS, DYRK2, EPM2AIP1, SORBS1 |
1034 | GO:2000300 | 0.04 | 3.73 | 4.59 | 8 | 11 | regulation of synaptic vesicle exocytosis | PFN2, SEPT5, RAB3A, RAP1A, STXBP1, SYN1, RIMS3, UNC13B |
1035 | GO:2000482 | 0.04 | 3.73 | 4.59 | 8 | 11 | regulation of interleukin-8 secretion | ANXA1, ANXA4, CD2, CD58, CRP, F2R, F2RL1, FCN1 |
1036 | GO:0007603 | 0.00 | 3.73 | 25.87 | 45 | 62 | phototransduction, visible light | ABCA4, APOA1, APOA4, APOC2, OPN1SW, CALM3, AKR1C4, CHRM1, CLPS, CNGA1, GPC4, GPC5, FNTA, OPN1MW, GPC3, GNAQ, GNAT1, GNB1, GNGT1, GPC1, GUCA1A, GUCA1B, GUCY2F, GUCY2D, PDE6G, PRKCA, PRKCQ, RBP1, RBP2, OPN1LW, RCVRN, RLBP1, RS1, SAG, SDC1, SDC2, SDC4, LRP8, AKR1C3, RGS9, SLC24A1, DHRS3, GUCA1C, SDC3, GPC6 |
1037 | GO:0051403 | 0.00 | 3.72 | 12.03 | 21 | 29 | stress-activated MAPK cascade | CAV3, CHUK, ATF2, CRYAB, DLG1, DUSP4, DUSP7, ELK1, HGF, JUN, PPP2R5D, MAPK3, RBM4, RPS6KA1, RPS6KA2, RPS6KA3, SKP1, NR2C2, EZR, CUL1, RPS6KA5 |
1038 | GO:0051223 | 0.00 | 3.71 | 33.75 | 59 | 82 | regulation of protein transport | ADRA2C, SLC25A4, ARL2, ARNTL, BNIP3L, CACNA1A, CACNA1E, CD40, CDKN2A, CHRM3, CNR1, CRP, EFNA5, ENSA, EPHA5, GJA5, GLP1R, GNAS, FOXA2, ITPR1, ITPR2, ITPR3, KCNA5, KCNS3, LLGL2, RAB8A, PAM, PCSK1, CDK16, PDE3B, PIK3C3, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PTPN1, PTPN14, RAP1A, RFX3, SLC2A2, SLC16A1, SNAP25, STXBP1, TRAF2, RAB11A, IQGAP1, SYT7, HMGN3, NRXN1, ATG5, NR1D1, CLOCK, CARTPT, SPCS2, RAPGEF4 |
1039 | GO:0036498 | 0.00 | 3.70 | 16.69 | 29 | 40 | IRE1-mediated unfolded protein response | ACADVL, ADD1, ASNA1, BAX, TPP1, DDX11, ERN1, EXTL3, HDGF, DNAJB9, DNAJC3, PTPN1, SHC1, SSR1, SULT1A3, WFS1, ZBTB17, ATP6V0D1, GOSR2, CUL7, BCL2L11, CTDSP2, PREB, PDIA6, AGR2, SEC61B, PDIA5, KDELR3, SEC63 |
1040 | GO:0006413 | 0.00 | 3.70 | 29.90 | 52 | 72 | translational initiation | EIF1AX, EIF4E, FAU, RPL10A, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, DDX3Y, EIF2S2, RPL14, EIF1AY, RPL23, RPL35 |
1041 | GO:0050878 | 0.00 | 3.70 | 153.67 | 264 | 370 | regulation of body fluid levels | A2M, ACTB, ACTG1, ACTN4, ACTN1, ADA, ADCY1, ADCY3, ADCY7, ADCY9, ADORA1, ADORA2A, ADRA2C, ALB, ANGPT1, ANGPT2, APOA1, APRT, AQP1, AQP5, ATP1B3, ATP2A1, ATP2B1, ATP2B2, ATP7B, AVP, AXL, CCND1, BSG, C1QBP, C3, DAGLA, CALM3, CALU, CAPZA1, CAPZB, CD2, CD9, ENTPD1, ENTPD2, CD40, CD44, CD48, CD58, CD59, CD63, CD74, CDC42, CDK5, CDO1, CENPE, CHRM1, CHRM3, CHUK, CLU, COL1A1, COL3A1, COPA, CSRP1, CXADR, CYBA, DGKA, DGKB, DGKQ, DHODH, CELSR2, EMP2, SLC29A1, EPHB2, F10, FBLN1, FGR, FLG, FLI1, FLNA, FYN, GAS6, GATA3, GATA4, GATA6, GGCX, GHRHR, GJA5, GNA15, GNAI1, GNAI3, GNAQ, GNAS, GNB1, SFN, GRB2, GRB7, GUCA1B, GUCA2B, GUCY1B3, H3F3B, HBD, HBG1, HBG2, SERPIND1, HGF, HIF1A, HK2, HSPB1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IGF1, IGF2, ILK, ITGA6, IRF1, IRF2, ITGA1, ITGA2, ITGA3, ITGA4, ITGA5, ITGAL, ITGAM, ITGAV, ITGAX, ITGB1, ITPR1, ITPR2, ITPR3, KCNN4, KIF5A, KLC1, KRAS, KRT16, LAMP2, LMAN1, NRAS, OLR1, P2RY1, P2RY2, PAM, SERPINA5, PDE3A, PDE3B, PDE1B, PDPK1, PF4, PF4V1, PFN1, PIK3CB, PIK3CG, PRCP, SRGN, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCB, PRKCE, PRKCG, PRKCZ, MAPK3, PTPN1, PTPN6, RAB27A, RAC1, RAC2, RAD51B, RAF1, RAP1A, RAP2B, SCNN1A, SCNN1B, SCNN1G, CX3CL1, SELE, SELL, SELPLG, SHC1, SHH, SLC8A1, SLC8A3, SLC16A1, SLC22A2, SOD1, SOS1, SPARC, SPN, SRF, STAT5B, STXBP1, STXBP3, TAC1, TP73, TRPC1, TRPC3, TUBA4A, TYRO3, UCN, NR1H2, USF2, VAV1, VCL, VDR, VEGFA, VEGFB, VEGFC, VIP, WEE1, WFS1, YWHAZ, LRP8, MAFK, SLC7A5, AKAP1, FZD6, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, DGKE, CYP4F2, AP3B1, TP63, PDE5A, VAMP8, RAB11A, CD84, PROZ, HIST1H3F, DOK2, PAPSS2, FIBP, DGKI, KIF3B, EIF2AK3, ATG5, BCAR1, GNA14, WDR1, SH2B3, RASGRP2, KCNMB2, ABCC4, HMG20B, RAPGEF3, VAV3, CAP1, ATG7, PROCR, AGR2, SH2B2, PDPN, PDE10A, EHD1, RAPGEF4, ADAMTS13, KIF3A, SLC7A9, AKAP10, HPS5 |
1042 | GO:0007611 | 0.01 | 3.69 | 7.45 | 13 | 18 | learning or memory | STS, DBI, EGR2, AFF2, GLP1R, GM2A, MAN2B1, SLC11A2, NTRK1, PRKAR1B, PRKCG, VIP, FZD9 |
1043 | GO:0000060 | 0.00 | 3.68 | 12.10 | 21 | 29 | protein import into nucleus, translocation | ARNTL, BCL3, BRCA1, CDKN1A, GAS6, HSP90AB1, IFNG, IGF1, KPNB1, TNPO1, IPO5, OGG1, OR1D2, RAN, SIX3, SLC11A1, AKR1C3, CEP57, NUTF2, SEC61B, PHB2 |
1044 | GO:0060401 | 0.00 | 3.67 | 30.05 | 52 | 72 | cytosolic calcium ion transport | ADCYAP1R1, ATP1A2, BAX, BCL2, BMP4, CALM3, CASQ2, CD4, CCR5, CTGF, CYBA, DIAPH1, EDNRA, F2R, XCR1, GSTM2, HRC, HTR2C, IL13, ITPR1, ITPR2, ITPR3, NTSR1, P2RX3, P2RX4, P2RX7, PDE4D, PDPK1, PLN, PRKACA, PRKCE, PRKD1, PTPN6, RYR1, RYR2, RYR3, CCL21, XCL1, SLC8A1, SLC8A3, SNCA, TRPC1, TRPC3, TRPM2, TRPV1, HAP1, GSTO1, AKAP6, ATG5, TRDN, CHERP, CORO1A |
1045 | GO:0048066 | 0.01 | 3.65 | 7.50 | 13 | 18 | developmental pigmentation | AP1G1, CD63, EDNRB, CITED1, RAB27A, SOX10, TYRP1, ZIC2, AP1M1, AP3D1, USP13, ATP6AP2, RAB32 |
1046 | GO:0042886 | 0.00 | 3.64 | 85.55 | 147 | 205 | amide transport | ABAT, ABCA1, ACVR2B, ADORA1, ADRA2C, SLC25A4, ANXA1, ANXA5, AQP1, AQP7, ARL2, ARNTL, BAD, BCL3, BLK, CA2, CACNA1A, CACNA1E, CAMK2G, CD38, CD74, CDH17, CFTR, CHRM3, CNR1, CYLD, EDA, EDN3, EFNA5, ENSA, EPHA5, FGA, FGG, FOLR3, GCG, GHRH, GHRHR, GHSR, GIP, GLP1R, GLUD1, GLUL, GNAS, GPLD1, GPR27, FFAR1, FFAR3, HIF1A, HMGCR, FOXA2, HTR2C, IFNG, IL1B, IL1RN, IL10, IL18, INS, ISL1, ITPR1, ITPR2, ITPR3, KCNA5, KCNJ11, KCNS3, KISS1, OXCT1, PARK2, PCSK1, CDK16, PDE3B, PDE4C, PFKFB2, PPM1A, PPM1B, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCE, PRKCQ, PTGER4, PTPRN, PTPRN2, RAB1A, RAF1, RAP1A, REST, RFX3, S100A8, S100A9, SLC2A2, SLC15A1, SLC15A2, SLC16A1, SNAP25, SOX4, SREBF1, STXBP1, STXBP3, ABCC8, TACR2, HNF1A, TRH, TRIP6, TRPM2, UCN, UPK3A, VIP, TRPV1, VSNL1, PAX8, SLC14A2, LTBP4, NR0B2, TNFSF11, TNFSF14, IL18R1, IQGAP1, ARHGEF7, SLC5A6, SYT7, RAB11B, HMGN3, SLC9A3R1, NRXN1, EIF2AK3, STXBP5L, LITAF, NR1D1, CLOCK, CARTPT, RIMS2, SPCS2, C2CD2L, NR1H4, COL4A3BP, RAPGEF3, RBCK1, CPLX1, EDAR, SLC38A3, RAPGEF4, CAPN10 |
1047 | GO:0007205 | 0.01 | 3.64 | 7.51 | 13 | 18 | protein kinase C-activating G-protein coupled receptor signaling pathway | CCK, CHRM1, CISH, DGKA, DGKB, DGKQ, EDNRA, F2R, GAP43, GRM1, DGKE, DGKI, PICK1 |
1048 | GO:0014003 | 0.01 | 3.64 | 7.51 | 13 | 18 | oligodendrocyte development | CD9, CLU, LPAR1, EIF2B1, FGFR3, KCNJ10, SHH, SOX11, CNTN2, EIF2B4, EIF2B3, EIF2B2, EIF2B5 |
1049 | GO:0032467 | 0.01 | 3.64 | 7.51 | 13 | 18 | positive regulation of cytokinesis | CDC6, CDC42, ECT2, OPN1MW, PRKCE, OPN1LW, SPAST, SVIL, CUL3, AURKB, KIF3B, GIPC1, CIT |
1050 | GO:0040018 | 0.01 | 3.64 | 7.51 | 13 | 18 | positive regulation of multicellular organism growth | BBS2, BBS4, BCL2, DIO3, GHRH, GHRHR, GHSR, IGF2, PPIB, STAT5B, VIL1, EZR, IKZF1 |
1051 | GO:0044091 | 0.01 | 3.64 | 7.51 | 13 | 18 | membrane biogenesis | ANXA2, CAV2, CAV3, EMP2, FLOT2, PTPRD, PEX19, S100A10, PEX11A, NRXN1, NRXN2, PEX16, IL1RAPL1 |
1052 | GO:0050775 | 0.01 | 3.64 | 7.51 | 13 | 18 | positive regulation of dendrite morphogenesis | CUX1, EPHA4, ILK, CAPRIN1, RELN, PTPRD, SGK1, CDKL5, LRP8, NUMBL, CUL7, BAIAP2, IL1RAPL1 |
1053 | GO:0051204 | 0.01 | 3.64 | 7.51 | 13 | 18 | protein insertion into mitochondrial membrane | BAD, BAX, BCL2, BID, CASP8, SFN, PPP3R1, MAPK8, YWHAG, YWHAH, YWHAZ, DYNLL1, BCL2L11 |
1054 | GO:0070423 | 0.01 | 3.64 | 7.51 | 13 | 18 | nucleotide-binding oligomerization domain containing signaling pathway | BIRC3, XIAP, CASP8, CHUK, CYLD, IRAK1, IRAK2, RPS27A, TNFAIP3, UBB, UBE2V1, IKBKG, RIPK2 |
1055 | GO:0071396 | 0.02 | 3.64 | 5.71 | 10 | 14 | cellular response to lipid | ADCY1, ADCY3, ALOX12, BAD, LPAR1, GNAI1, GPLD1, HMGCS1, PTCH1, LRP8 |
1056 | GO:0071356 | 0.00 | 3.63 | 16.12 | 28 | 39 | cellular response to tumor necrosis factor | ASS1, BRCA1, ENTPD2, CD58, CHI3L1, COL1A1, CYBA, GATA3, KAT2A, GPD1, HAS2, ICAM1, KCNJ11, NTRK2, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, XCL2, TRPV1, ARHGEF2, HDAC4, IL18BP, KLF2, ADAMTS7 |
1057 | GO:0043410 | 0.00 | 3.63 | 11.44 | 20 | 28 | positive regulation of MAPK cascade | ADRA1B, ADRB2, CAV2, EPHA8, IGF1, IGF1R, IGF2, IGFBP3, INS, ITGB1, KISS1, NTRK2, TNFRSF11B, PRKCE, RYK, SOX2, TNFRSF1B, TNFRSF4, TNFRSF6B, SORBS3 |
1058 | GO:0007160 | 0.00 | 3.63 | 23.70 | 41 | 57 | cell-matrix adhesion | CD44, CD63, CDK5, CDKN2A, COL3A1, COL17A1, CTGF, ECM2, EDA, FGA, FGG, ONECUT1, HOXD3, ITGA6, ITGA1, ITGA3, ITGA4, ITGA7, ITGAL, ITGAV, ITGB1, ITGB4, ITGB5, BCAM, SERPINE1, PIK3CB, SIGLEC1, SRF, CNTN2, VCL, VTN, MADCAM1, ITGA8, ADAM15, ADAM9, SGCE, ONECUT2, SEMA3E, BCL2L11, FBLN5, ADAMTS13 |
1059 | GO:0001503 | 0.00 | 3.63 | 19.00 | 33 | 46 | ossification | ACP5, ATP6V1B1, BMP1, BMP8B, COL2A1, COL5A2, COL10A1, COL11A1, CTGF, CTSK, EGR2, EXT1, EXT2, GPLD1, IGF2, INPPL1, OXT, PBX1, MAPK8, RPL38, RYR1, SORT1, SLC34A1, SP1, SP3, SPARC, STC1, TAC1, TNFSF11, DCHS1, DHRS3, FSTL3, SIX2 |
1060 | GO:0008361 | 0.00 | 3.63 | 10.40 | 18 | 25 | regulation of cell size | ARHGAP5, ATP2B2, CAV3, CDK4, HIF1A, HSP90AB1, RAC1, RDX, TP73, TSC1, UCN, VAV1, XK, OGT, SLC9A3R1, RB1CC1, RAPGEF3, VAV3 |
1061 | GO:0030324 | 0.00 | 3.62 | 26.62 | 46 | 64 | lung development | ACVR2B, ADA, ARG1, BMPR1A, BMPR2, CHI3L1, CP, CTGF, CUX1, CYP1A2, DHCR7, EDN2, EIF4E, EIF4EBP1, EP300, FGF1, FGF9, GPC3, HMGCS2, HES1, HSD11B1, IGFBP5, ITGA3, KDR, LAMA5, LIPA, PGR, PPP1CA, PROX1, PTHLH, PTK7, PTN, RAB3A, SFTPD, SP1, SP3, SPARC, SREBF1, VEGFA, WNT11, IFT88, ALDH1A2, ADAMTS2, PHF14, FSTL3, PDPN |
1062 | GO:0045682 | 0.00 | 3.60 | 10.43 | 18 | 25 | regulation of epidermis development | ALOX15B, ATOH1, BMP4, CDH3, CYP27B1, SFN, HES1, KRT84, REG3A, PTCH1, SFRP4, SRSF6, VDR, FOXN1, TP63, PTCH2, TRADD, TRIM16 |
1063 | GO:0048260 | 0.00 | 3.60 | 10.43 | 18 | 25 | positive regulation of receptor-mediated endocytosis | ANGPT1, BICD1, CAV3, CBL, CD63, DAB2, HIP1, NTF3, SERPINE1, PPT1, CCL21, SELE, SFRP4, SYK, VEGFA, VTN, SYNJ1, PICK1 |
1064 | GO:0046879 | 0.00 | 3.58 | 11.53 | 20 | 28 | hormone secretion | ACVR2B, AGTR2, AQP1, CAMK2G, GATA3, IL1RN, PTPRN, PTPRN2, RAB1A, RAF1, STXBP3, HNF1A, VIP, FZD4, LTBP4, SNAP23, RAB11B, EIF2AK3, RIMS2, CPLX1 |
1065 | GO:0034162 | 0.00 | 3.58 | 13.35 | 23 | 32 | toll-like receptor 9 signaling pathway | CHUK, ATF2, DUSP4, DUSP7, ELK1, IRAK1, IRAK2, JUN, PIK3C3, PPP2R5D, MAPK3, MAPK8, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, UBB, UBE2V1, CUL1, IKBKG, RIPK2, RPS6KA5 |
1066 | GO:2001244 | 0.00 | 3.58 | 13.35 | 23 | 32 | positive regulation of intrinsic apoptotic signaling pathway | BAD, BAX, BCL2, BCL2L1, BID, BUB1, CLU, DFNA5, PARK2, RPS3, S100A8, S100A9, SFPQ, SIAH1, SOD1, TP73, UBB, PRKRA, SLC9A3R1, EIF2AK3, BCLAF1, BCL2L11, SERINC3 |
1067 | GO:0009605 | 0.00 | 3.57 | 191.09 | 331 | 485 | response to external stimulus | ABL2, ACADS, ACAT1, ACTB, ACTG1, ADSL, AES, ALB, ALDH3A1, ALDH1A3, ALDOB, ANGPT1, SHROOM2, ASGR1, ATF3, ATF4, ATOH1, ATP2B1, BCHE, CCND1, BRCA1, BRCA2, CACNA1A, CACNA1S, CAMK2A, CAMK2G, CAT, CBS, CCNE1, CD63, CD72, CDC42, CDK5, CDKN1A, CDKN2D, CHN1, CLTA, CCR3, CCR8, ACKR2, COL2A1, COL4A3, COL4A4, COL4A5, COL5A1, COL5A2, COL6A2, COL6A3, COL9A1, COL9A3, COX4I1, CP, CRY1, CRY2, CSF2RB, CSNK2A1, CTSV, CYP24A1, DAD1, DCC, DCX, DHODH, DLG1, DLG3, DLX5, DNM1, DNMT3A, DNMT3B, DPYSL3, DSC2, HBEGF, DUSP5, DUSP7, DUSP9, TYMP, EEF2, EFNA1, EFNA3, EFNA4, EFNA5, EGR2, EGR3, EPHA2, ENSA, EPHA1, EPHA3, EPHA5, EPHA7, EPHA8, EPHB2, EPHB3, ERBB2, ERCC1, EREG, ETV4, EXT1, ACSL1, ACSL3, ACSL4, FGF3, FGF6, FGF8, FGF9, FGFR3, FGFR4, FLT1, FPR1, FPR2, FPR3, GAST, G6PC, GAP43, GCGR, GDNF, GFRA1, GHRH, GIP, GLUL, CCR10, XCR1, GRB2, ARHGAP35, GSS, SERPIND1, HGF, HLCS, HMBS, HMGCL, HMGCS1, NR4A1, HRH1, HSPA8, HSP90AA1, HSP90AB1, HTR2C, IL2RB, IL2RG, INHA, ITGA6, ITGA1, ITGA5, ITGA9, ITGAV, KIF5A, KRAS, LDHA, ABLIM1, LIMK1, LSP1, MARK3, KITLG, MGMT, NUDT1, NRAS, NRCAM, NRTN, NTN3, OGG1, OPHN1, OR1D2, OTC, OTX2, OXCT1, PEBP1, PAX2, PCK1, CHMP1A, ENPP2, PIK3C3, PIK3CB, PIM1, PPP1CA, PPP5C, PRKAA1, PSPN, PROX1, RELN, PSMA1, PSMA4, PSMA5, PSMA7, PSMB1, PSMB2, PSMB5, PSMB7, PYY, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTN, PTPRA, PTPRJ, PTPRM, RAB13, RALA, RASA2, RBM4, RHAG, RHCE, RHD, RNASE2, RPL24, RPS6KA1, RPS6KA2, RPS27A, RRAS, RXRA, RYK, SAA4, SATB1, SCN5A, CCL25, SDCBP, ITSN1, SHC1, SHH, SIAH1, SIAH2, SIPA1, SKP2, SLC6A4, SLC16A1, SLC34A1, SLC22A3, SLIT1, SLIT3, SOD1, SORD, SOS1, SOS2, SPTA1, SPTB, SRD5A1, SRF, SSTR2, SSTR3, STC1, SUOX, CNTN2, KLF10, TRIO, TRPC1, TRPC4, TRPC5, TSC2, TSHB, TYMS, TYROBP, UBB, UPP1, USF2, VAV1, VDR, EZR, WNT11, WNT2B, WRN, ZFP36, FZD3, ARHGEF5, FGF23, SOX14, CUL3, CNTNAP1, HAT1, KLF7, UNC5C, NUMB, PEA15, NRP2, ALDH1A2, ARHGEF7, KYNU, AP3D1, RPS6KA4, KALRN, USP2, AIFM1, RPS6KA5, NRXN3, LIPG, EIF2AK3, PICK1, PSMF1, ADAMTS1, BCAR1, RAPGEF2, FARP2, PSMD6, SETDB1, RBX1, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, PSME3, VAV3, CAP2, CAP1, ARPC1A, DPYSL4, GAS2L1, CXCR6, RRAGA, NRG3, CHL1, CCR9, FRS3, RAB32, SLC38A3, SLC27A4, VAX1, CORO1A, PTGDR2 |
1068 | GO:0031623 | 0.00 | 3.57 | 19.20 | 33 | 46 | receptor internalization | ACHE, ADRBK1, ADRBK2, ANGPT1, ANXA2, ARF1, CALCR, CAV3, CD9, CD36, CD63, CLTC, DNM1, DNM2, FCER1G, GRB2, GRIA1, ITGB1, NTF3, SDCBP, SELE, SFRP4, SNCA, SYK, CNTN2, VEGFA, EZR, PICALM, PICK1, CALCRL, RAMP2, RAMP3, RAB31 |
1069 | GO:0031571 | 0.00 | 3.56 | 22.12 | 38 | 53 | mitotic G1 DNA damage checkpoint | ATM, CCND1, CDKN1A, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SOX4, TP73, UBB, TP63, CRADD, PSMF1, PSMD6, PSME3 |
1070 | GO:0034142 | 0.00 | 3.56 | 22.12 | 38 | 53 | toll-like receptor 4 signaling pathway | BIRC3, BTK, CASP8, CD14, CD36, CHUK, ATF2, DUSP4, DUSP7, ELK1, F2RL1, IRAK1, IRAK2, ITGAM, JUN, LTF, PPP2R5D, PRKCE, MAPK3, MAPK8, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, TNFAIP3, UBB, UBE2D1, UBE2D2, UBE2V1, CUL1, IKBKG, RIPK1, RIPK2, RPS6KA5, NR1D1, TRIL, NR1H4 |
1071 | GO:0035051 | 0.00 | 3.56 | 25.04 | 43 | 60 | cardiocyte differentiation | ACVR1, AGTR2, BMP4, CAV3, CCNB1, CXADR, EFNB2, GATA4, GATA6, KAT2A, NRG1, HES1, RBPJ, ISL1, ITGB1, MAPK3, PROX1, RARA, RARB, REST, RXRA, SGCB, SLC8A1, SLC9A1, SRF, T, TSC1, TWIST1, COL14A1, VEGFA, CSRP3, IFT88, EOMES, SORBS2, HDAC3, CTDP1, HAND2, AKAP6, ATG5, SPEG, ATG7, PDLIM5, BVES |
1072 | GO:0071560 | 0.01 | 3.54 | 8.71 | 15 | 21 | cellular response to transforming growth factor beta stimulus | ARG1, COL1A1, CX3CR1, DNMT1, FYN, PDE3A, PENK, XCL1, SOX5, SOX9, STAR, CLEC3B, WNT2, STK16, RAPGEF3 |
1073 | GO:0044070 | 0.02 | 3.53 | 5.81 | 10 | 14 | regulation of anion transport | ARG1, ATP1A2, CA2, CA7, CACNA1A, SEPT2, STC1, SYK, RAB11B, AHCYL1 |
1074 | GO:0044419 | 0.00 | 3.53 | 160.78 | 273 | 389 | interspecies interaction between organisms | ADAR, ADARB1, AP2A1, AP2B1, AP1G1, AMBP, BIN1, SLC25A4, AQP1, ARF1, BAX, BCL2, BICD1, BNIP3, BNIP3L, BST2, BUB1, C1QBP, CAMLG, CASP8, CCNH, CCNT1, CCNT2, CD28, CD36, CDC25C, CDK9, CENPA, CHD1, AP2M1, AP1S1, AP2S1, CCR3, COPB1, CTSG, CX3CR1, DDB1, DDX3X, DDX5, DDX6, DDX11, DLG1, DMBT1, DYNC1I2, E4F1, EPHA2, EIF4A1, EIF4A2, EIF4E, EIF4G1, EP300, STOM, ERCC3, F2RL1, FAU, FCGR2B, FDPS, FYN, KAT2A, GFI1, GPX1, GRB2, GTF2F1, HCK, HMGA1, HPN, HPX, HSPA8, HSP90AB1, IFI16, SP110, IFNG, IL2RB, IL2RG, IL10, ISG20, JUN, KDR, KLC1, TNPO1, IPO5, KRT7, KRT18, KRT19, MAP3K5, MFGE8, RPL10A, OAS1, OAS3, OSBP, CHMP1A, PCSK5, PPIB, PPID, MAPK3, PROX1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RAB1A, RAB6A, RAC1, RALA, RAN, RB1, RBL1, REST, ABCE1, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, SATB1, SET, SGTA, SHC1, SKP1, SLPI, SMARCA4, SP1, SP100, SRPK2, SSRP1, STAT2, STAT3, STAU1, SUPT4H1, SUV39H1, SYK, TAF2, TAF4B, TAF5, TAF6, TAF13, TARBP2, TBP, TSPAN7, TNFRSF1A, TOP1, TOP2A, TP73, TSC2, TSG101, UBB, UBE3A, SUMO1, UNG, USF1, USF2, VIM, EIF4H, XRCC4, RAB7A, CUL5, CUL4A, CUL2, CUL1, IKBKG, CDK13, OASL, DYNLL1, BECN1, RNGTT, BANF1, CFLAR, KAT2B, AP1S2, AP1M1, PGLYRP1, RPL14, CLDN6, CTDP1, RPL23, RAB9A, ATG5, PSMF1, KDM4A, USP6NL, VPRBP, IST1, CUL7, ELMO1, PSMD6, RBX1, ACOT8, ABI1, PDCD6IP, AP1M2, RAD50, ABI2, TRIM28, WASF2, ALYREF, PSME3, TRIM22, PPIE, PPIH, NXF1, CREB3, CARM1, RBCK1, IVNS1ABP, CXCR6, ZMYND11, SRCAP, COPS6, SF3B2, ATF7, PSIP1, SUPT16H, RPL35, SNF8 |
1075 | GO:1903524 | 0.02 | 3.52 | 5.82 | 10 | 14 | positive regulation of blood circulation | ADA, CTGF, EDN2, EDN3, HRC, KCNQ1, PDE4D, RGS2, RYR2, TACR3 |
1076 | GO:0010634 | 0.00 | 3.52 | 11.66 | 20 | 28 | positive regulation of epithelial cell migration | AQP1, HBEGF, FGF7, HAS2, HIF1A, IFNG, INSL3, ITGA2, ITGA3, JUN, ENPP2, PFN1, PRKCE, RREB1, SOX9, TAC1, VIL1, ADAM9, RAB11A, HDAC6 |
1077 | GO:0006367 | 0.00 | 3.52 | 55.09 | 94 | 132 | transcription initiation from RNA polymerase II promoter | NR0B1, AHR, RUNX2, CCNC, CCNH, CCNT1, CCNT2, CDK8, CDK9, COX4I1, COX5B, COX6A1, COX6B1, COX7B, COX7C, COX8A, CTGF, E2F2, E2F4, E2F5, ERCC3, ESR1, ESRRG, NR5A1, NR6A1, GLS, SFN, GPX2, GTF2F1, GTF2I, NR4A1, HNF4G, RBPJ, JUNB, SMAD3, SMAD7, MAZ, MEN1, SERPINE1, PGR, PPM1A, PRKAA1, PRKAB2, PSMC1, PSMC3, PSMC4, PSMC5, RARA, RARB, RBL1, RHEB, RPS27A, RXRA, RXRG, SP1, SRF, TAF2, TAF4B, TAF5, TAF6, TAF7, TAF13, TBP, HNF1A, PRDX2, NR2F1, NR2E1, NR2C1, NR2C2, TSC1, TSC2, UBB, UBE2D1, NR1H2, VDR, YWHAG, YWHAH, YWHAZ, ZNF45, USP9X, NR0B2, TP63, KAT2B, NR1I2, COX7A2L, COX5A, NR1D1, NR1I3, NR1H4, NR1D2, NR2E3, TRIM28, IKZF1, RRAGA |
1078 | GO:1901568 | 0.00 | 3.51 | 17.53 | 30 | 42 | fatty acid derivative metabolic process | ACOX1, ALOX12, ALOX15B, ANXA1, AVP, DAGLA, CD74, CYP1A2, CYP2A6, CYP2A13, CYP2F1, DPEP1, EDN2, FAAH, FCER1A, GGT7, GPX1, HPGD, LTA4H, MGST2, MAPK3, PTGIS, PTGS1, RNPEP, SYK, TNFRSF1A, CYP4F2, AKR1C3, PRG3, PDPN |
1079 | GO:0035019 | 0.00 | 3.51 | 11.68 | 20 | 28 | somatic stem cell population maintenance | APC, ASCL2, BCL9, ZFP36L2, CDX2, EPHA1, FGFR3, HES1, RBPJ, KIT, PBX1, RAF1, SOX2, SOX4, SOX9, STAT3, KLF10, NR2E1, CUL4A, KLF4 |
1080 | GO:0006283 | 0.00 | 3.51 | 14.61 | 25 | 35 | transcription-coupled nucleotide-excision repair | CCNH, DDB1, EP300, ERCC1, ERCC3, ERCC4, ERCC5, ERCC6, HMGN1, RFC1, RFC2, RFC3, RFC4, RFC5, RPA3, RPS27A, UBB, XPA, CUL4B, CUL4A, COPS3, RBX1, PPIE, COPS8, COPS6 |
1081 | GO:1904035 | 0.00 | 3.51 | 14.61 | 25 | 35 | regulation of epithelial cell apoptotic process | ABL2, ANGPT1, BMP4, KRIT1, CD40, EIF2S1, FGA, FGG, GAS6, GATA3, ICAM1, IGF1, IL13, KDR, SERPINE1, SERPINB13, PRKCI, SORT1, SFRP4, TNFAIP3, WFS1, SCG2, AKR1C3, RAMP2, CAPN10 |
1082 | GO:0010035 | 0.00 | 3.51 | 54.77 | 94 | 133 | response to inorganic substance | ABAT, ACO1, ACP5, ALB, ALDOB, ANXA11, APBB1, APOA4, ASS1, ATP12A, ATP5D, ATP7B, BAX, CCND1, BGLAP, BSG, C1QA, C3, CA2, CALM3, CASP8, CASP9, CASQ2, CD9, CD14, CD36, ENTPD6, CDK4, CLU, CP, CPOX, CPS1, ATF2, DHFR, DNMT3A, DTYMK, EEF1A2, ERCC6, FANCC, FECH, FGA, FGG, GDI1, GSS, HMGCS1, HMGCS2, ICAM1, IGFBP2, IL1A, IL1B, ITPR3, KHK, KRT14, LCAT, LTA4H, SLC11A2, NTRK1, TNFRSF11B, OTC, P2RX7, PAM, PAWR, PENK, PGAM2, PLN, PTCH1, QDPR, RYR2, S100A8, S100A13, SIPA1, SOD2, SORD, SPARC, ABCC8, TAT, PRDX2, TNNC1, TNNT2, TRPC1, TRPC3, TSHB, SCGB1A1, SLC30A1, SLC30A2, FGF23, SLC14A2, GGH, RGN, PDCD6, SLC25A13, KCNMB2, FBLN5, AHCYL1 |
1083 | GO:0007618 | 0.00 | 3.50 | 11.69 | 20 | 28 | mating | ABAT, ACVR2A, ADA, APLP2, AVP, CNR1, EDNRA, EDNRB, GRN, HEXB, OXT, P2RY1, P2RY2, PI3, SEMG1, SLC6A4, TAC1, VIP, DDO, EDDM3A |
1084 | GO:0031102 | 0.00 | 3.50 | 11.69 | 20 | 28 | neuron projection regeneration | APOA1, APOA4, BCL2, TSPO, CALU, CTNNA1, DHFR, EPHA4, GFAP, HGF, TNC, ISL1, JUN, NTRK3, PRRX1, RXRA, TNR, KLF4, NREP, CHST3 |
1085 | GO:0051084 | 0.00 | 3.50 | 11.69 | 20 | 28 | 'de novo' posttranslational protein folding | ACTB, CD74, TBCB, HSPA8, PFDN1, PFDN2, TBCA, TBCD, TBCE, CCT3, TUBA4A, TUBA3C, VBP1, TUBA1A, SEP15, TUBA1B, CCT7, CCT4, CCT2, CCT8 |
1086 | GO:0043303 | 0.02 | 3.50 | 5.84 | 10 | 14 | mast cell degranulation | KIT, PDPK1, PIK3CG, RAC2, S100A13, STXBP2, LAT2, SNAP23, CD84, CPLX2 |
1087 | GO:0042770 | 0.00 | 3.50 | 36.31 | 62 | 87 | signal transduction in response to DNA damage | ATM, ATR, ATRX, BCL3, BID, BRCA1, BRCA2, CASP9, CD44, CD74, CDC5L, CDKN1A, CDKN2A, GADD45A, DDX5, DYRK1A, GRB2, HIC1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SNAI2, SNAI1, SOX4, SP100, TP73, TWIST1, UBB, WNT1, SMC1A, TP63, CRADD, PSMF1, PSMD6, PSME3, MAD2L2, BATF, CHEK2 |
1088 | GO:0046928 | 0.02 | 3.50 | 5.84 | 10 | 14 | regulation of neurotransmitter secretion | CACNA1A, CAMK2A, CHRNB4, NTRK2, PARK2, PTGER4, SNCA, TACR2, SLC30A1, SNCAIP |
1089 | GO:0009083 | 0.01 | 3.50 | 8.76 | 15 | 21 | branched-chain amino acid catabolic process | ACADSB, ACAT1, ALDH9A1, AUH, BCAT1, BCAT2, BCKDHA, DLD, HSD17B10, HMGCL, IVD, ALDH6A1, SHMT1, BBOX1, BCKDK |
1090 | GO:0032720 | 0.01 | 3.50 | 8.76 | 15 | 21 | negative regulation of tumor necrosis factor production | ACP5, AXL, BCL3, BPI, TSPO, GAS6, GHSR, IL10, PTGER4, RARA, SLAMF1, TNFAIP3, TWIST1, NR1H4, GPNMB |
1091 | GO:0035987 | 0.01 | 3.50 | 8.76 | 15 | 21 | endodermal cell differentiation | COL5A1, COL5A2, COL11A1, COL12A1, GATA6, HSBP1, ITGA4, ITGA5, ITGA7, ITGAV, ITGB5, LAMA3, SOX2, VTN, EOMES |
1092 | GO:0043471 | 0.01 | 3.50 | 8.76 | 15 | 21 | regulation of cellular carbohydrate catabolic process | ADRA1B, ARNT, BPGM, GPD1, HIF1A, IGF1, INS, P2RX7, PGAM2, PPP1CA, PRKAA1, STAT3, OGT, HDAC4, ECD |
1093 | GO:0060338 | 0.01 | 3.50 | 8.76 | 15 | 21 | regulation of type I interferon-mediated signaling pathway | ADAR, UBE2K, HSP90AB1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, PTPN1, PTPN6, STAT2, TYK2, SOCS3, CDC37, USP18 |
1094 | GO:0000722 | 0.02 | 3.50 | 5.84 | 10 | 14 | telomere maintenance via recombination | FEN1, PRIM1, PRIM2, RAD51, RFC1, RFC2, RFC3, RFC4, RFC5, RPA3 |
1095 | GO:0002052 | 0.02 | 3.50 | 5.84 | 10 | 14 | positive regulation of neuroblast proliferation | CX3CR1, HIF1A, CX3CL1, SHH, SMARCD3, SOX2, SOX10, VEGFA, VEGFC, FZD3 |
1096 | GO:0006691 | 0.02 | 3.50 | 5.84 | 10 | 14 | leukotriene metabolic process | ALOX12, DPEP1, FCER1A, GGT7, LTA4H, MGST2, RNPEP, SYK, CYP4F2, PRG3 |
1097 | GO:0015874 | 0.02 | 3.50 | 5.84 | 10 | 14 | norepinephrine transport | ADRA2C, AGTR2, FFAR3, OXT, P2RY1, PTGS1, SLC6A2, SLC22A1, SNCA, HRH3 |
1098 | GO:0031641 | 0.02 | 3.50 | 5.84 | 10 | 14 | regulation of myelination | DLG1, HGF, NRG1, IFNG, RARA, RARB, RXRA, EIF2AK3, FIG4, RNF10 |
1099 | GO:0035162 | 0.02 | 3.50 | 5.84 | 10 | 14 | embryonic hemopoiesis | FLT3LG, GATA3, HIF1A, KDR, KIT, KITLG, PBX1, TAL1, VEGFA, SH2B3 |
1100 | GO:0050996 | 0.02 | 3.50 | 5.84 | 10 | 14 | positive regulation of lipid catabolic process | ADRB2, AKT2, APOA1, APOA4, APOC2, APOH, IL1B, PRKCE, TWIST1, SPTLC1 |
1101 | GO:0071353 | 0.02 | 3.50 | 5.84 | 10 | 14 | cellular response to interleukin-4 | ALAD, ARG1, GATA3, HSP90AB1, IL2RG, IMPDH2, XCL1, TUBA1B, IL24, CORO1A |
1102 | GO:0085029 | 0.02 | 3.50 | 5.84 | 10 | 14 | extracellular matrix assembly | GAS6, GPM6B, HAS1, HAS2, HAS3, IHH, SMAD3, SOX9, RAMP2, FBLN5 |
1103 | GO:0030802 | 0.00 | 3.48 | 27.54 | 47 | 66 | regulation of cyclic nucleotide biosynthetic process | ABCA1, ADCY7, ADCYAP1R1, ADORA2A, ADRB2, APLP1, AVP, AVPR2, CALCR, CALM3, LPAR1, EDNRA, EDNRB, FSHR, GALR1, GCG, GHRH, GHRHR, GLP1R, GNAI3, GNAL, GNAS, GRM8, GUCA1A, GUCA1B, GUCA2A, GUCA2B, INSL3, NTRK1, NTRK2, P2RY11, PRKCA, PTGER4, PTHLH, RAF1, RCVRN, UCN, VIP, VIPR2, WFS1, AKAP6, GABBR2, GUCA1C, CALCRL, RAMP2, CAP2, CAP1 |
1104 | GO:0006446 | 0.00 | 3.48 | 24.62 | 42 | 59 | regulation of translational initiation | ATF4, DAZ1, DDX1, DDX3X, EIF2S1, EIF2B1, EIF4A1, EIF4A2, EIF4B, EIF4EBP1, EIF4EBP2, EIF4G1, EIF4G2, EIF5, FECH, HSPB1, EIF3E, PPP1CA, EIF2AK2, DNAJC3, RARA, RBM4, RPS6KB2, RXRA, EIF4H, EIF3A, EIF3B, EIF3D, EIF3F, EIF3G, EIF3J, EIF2B4, EIF2B3, EIF2B2, EIF2B5, EIF2AK3, EIF5B, CTIF, EIF1, EIF1B, EIF3M, KHDRBS1 |
1105 | GO:0060759 | 0.00 | 3.47 | 34.64 | 59 | 83 | regulation of response to cytokine stimulus | ADAR, AES, ANGPT1, BIRC3, APOA1, AXL, CASP8, CD74, CHUK, CYLD, ECM1, F2RL1, GAS6, GFI1, HIF1A, UBE2K, HPX, HSP90AB1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNGR1, IL1RN, IRAK1, IRAK2, PARK2, PTPN1, PTPN6, RPS27A, SLIT3, STAT2, SYK, TNFAIP3, TNFRSF1A, TRAF1, TRAF2, TYK2, UBB, SUMO1, NR1H2, PXDN, IKBKG, MADD, TRADD, RIPK1, RIPK2, TAX1BP1, CPNE1, SOCS3, KLF4, SLIT2, TRAIP, AGPAT2, RBCK1, CDC37, USP18 |
1106 | GO:0030218 | 0.00 | 3.47 | 21.70 | 37 | 52 | erythrocyte differentiation | ACVR1B, ACVR2A, ADAR, ADD1, ALAS2, ARNT, BMP4, CDK6, CEBPG, DNASE2, EPB42, ETS1, ETV2, FECH, GATA3, HCLS1, HIF1A, PRMT1, INHA, KIT, SLC11A2, RB1, ARID4A, RHAG, RPS19, SP1, SP3, SRF, STAT5B, TAL1, VEGFA, ZNF16, PTBP3, IKZF1, KLF2, GAS2L1, KLF1 |
1107 | GO:0006935 | 0.00 | 3.47 | 153.82 | 260 | 372 | chemotaxis | ABL2, ACTB, ACTG1, AP2A1, AP2B1, ANXA1, ATOH1, CACNA1S, CACNB4, CALM3, CAMK2A, CAMK2G, CD72, CDC42, CDK5, CHN1, AP2M1, AP2S1, CLTA, CCR3, CCR5, CCR8, ACKR2, COL2A1, COL3A1, COL4A3, COL4A4, COL4A5, COL5A1, COL5A2, COL6A2, COL6A3, COL9A1, COL9A3, CSF2, CSF2RB, CSNK2A1, CSNK2A2, CX3CR1, CXADR, DCC, DCX, DEFA1, DLG1, DLG3, DLX5, DNM1, DPYSL3, HBEGF, DUSP5, DUSP7, DUSP9, TYMP, EDNRB, EFNA1, EFNA3, EFNA4, EGR2, EGR3, EPHA2, EPHA1, EPHA3, EPHA4, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, ERBB2, EREG, ETV1, ETV4, EXT1, FCER1G, FGF3, FGF6, FGF9, FGFR3, FGFR4, FLT1, FPR1, FPR2, FPR3, FYN, GAP43, GATA3, GDNF, GFRA1, GPC1, CCR10, XCR1, GRB2, GRIN2A, ARHGAP35, SERPIND1, NR4A1, HRH1, HSPA8, HSP90AA1, HSP90AB1, IFNG, IL2RA, IL2RB, IL2RG, IL10, ISL1, ITGA1, ITGA5, ITGA9, ITGB1, KIF5A, KIT, KRAS, ABLIM1, LIMK1, LSP1, MARK3, KITLG, NRAS, NRCAM, NRTN, NTRK1, NTN3, OPHN1, OR1D2, OTX2, PEBP1, PDE4B, PDE4D, ENPP2, PIK3CB, PIK3CG, PPP5C, PRKCQ, MAPK3, PSPN, RELN, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTAFR, PTPRA, PTPRM, RAB13, RAF1, RALA, RASA2, RNASE2, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS19, RPS27A, RRAS, S100A8, S100A9, S100A12, SCN5A, CCL20, CCL22, CCL24, CCL25, SDC2, SDCBP, SFTPD, ITSN1, SHC1, SHH, SIAH1, SIAH2, SOS1, SOS2, SPN, SPTA1, SPTB, XCL2, SYK, CNTN2, TNR, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, VAV1, EZR, FZD3, ARHGEF5, FOSL1, FGF23, CUL3, SEMA7A, CNTNAP1, TNFSF11, KLF7, UNC5C, NUMB, PEA15, NRP2, ARHGEF7, RPS6KA4, KALRN, RPS6KA5, NRXN3, NRXN1, PSMF1, BCAR1, FEZ2, RAPGEF2, FARP2, PSMD6, RBX1, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, PSME3, SPON2, VAV3, CAP2, CAP1, ARPC1A, DPYSL4, CXCR6, CHL1, CCR9, FRS3, VAX1, PTGDR2 |
1108 | GO:0051592 | 0.00 | 3.46 | 15.83 | 27 | 38 | response to calcium ion | ANXA5, ANXA11, BAD, CCND1, CALM3, CASQ2, ENTPD6, DUSP1, FGA, FGG, GDI1, ITPR3, P2RX7, PENK, RYR2, SDC1, SPARC, TNNT2, TRPC1, TRPC3, TSHB, ADAM9, PDCD6, SLC25A13, KCNMB2, TXNIP, AHCYL1 |
1109 | GO:0006091 | 0.01 | 3.45 | 6.98 | 12 | 17 | generation of precursor metabolites and energy | ACOX1, AQP7, ASIP, AVP, RUNX1T1, COX6A2, COX7A1, FDXR, FECH, NRF1, XYLB, COX17 |
1110 | GO:0034110 | 0.00 | 3.45 | 44.09 | 75 | 106 | regulation of homotypic cell-cell adhesion | ADA, ADK, BAD, CAMK4, CD2, CD3D, CD3G, CD4, CD5, CD6, CD28, CD80, CD86, CD44, CD59, CDC42, CLC, CD55, DHPS, DPP4, EFNB2, EGR3, FLOT2, FYN, GATA3, GRB2, HAS2, HLA-DQA1, HES1, IFNG, IGF1, IGF2, IGFBP2, IL1B, IL18, ITGAL, ITPKB, LMO1, CD46, PDPK1, PRKCA, PRKCQ, PRKCZ, RAC1, RAC2, RAG1, RARA, CCL21, SOD1, SOS1, SOS2, SPTA1, STAT5B, SYK, TRAF2, VAV1, ZP3, FOXN1, AP3B1, TNFSF11, TNFSF14, TNFSF9, RIPK2, IL1RL2, VNN1, BCL10, AP3D1, SOX13, EBI3, IKZF1, TNFSF13B, MALT1, SPINK5, HHLA2, CORO1A |
1111 | GO:0038095 | 0.00 | 3.44 | 69.69 | 118 | 167 | Fc-epsilon receptor signaling pathway | ANGPT1, BAD, BTK, CALM3, CAMK2A, CAMK2G, CASP9, CD28, CD80, CD86, CDKN1A, CHUK, CSF2, CSF2RB, HBEGF, DUSP5, DUSP7, DUSP9, ERBB2, EREG, FCER1A, FCER1G, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FYN, GRB2, GRIN2A, NRG1, NR4A1, IL2RA, IL2RB, IL2RG, ITPR1, ITPR2, ITPR3, JUN, KIT, KRAS, MARK3, KITLG, FOXO4, NRAS, PEBP1, PDPK1, PIK3CB, PPP3R1, PPP5C, PRKCQ, MAPK3, MAPK8, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPRA, RAC1, RAF1, RASA2, RPS6KB2, RPS27A, SHC1, SKP1, SOS1, SPTA1, SPTB, SYK, TSC2, UBB, UBE2D1, UBE2D2, UBE2V1, VAV1, LAT2, FGF23, CUL3, CUL1, IKBKG, PEA15, BCL10, PSMF1, RAPGEF2, GAB2, PSMD6, RBX1, AKAP9, RASA4, PSME3, VAV3, FRS3, MALT1 |
1112 | GO:0008285 | 0.00 | 3.43 | 107.06 | 181 | 258 | negative regulation of cell proliferation | ADARB1, ADORA1, AGTR2, ALOX15B, ATM, AZGP1, BAX, BCHE, BCL2, BDKRB2, PRDM1, BMPR2, BTG1, CBLB, CD9, TNFRSF8, CD37, CDC6, CDKN1A, CDKN2A, CDKN2C, CDKN2D, COL4A3, CTLA4, CTNNA1, CXADR, CYP27B1, DFNA5, DHCR24, DLG3, EMD, EMP3, ERBB2, ETS1, ETV3, F2R, FABP6, FABP7, FAP, FBLN1, FGFR3, FLT3, FRK, GAS8, B4GALT1, GPLD1, RAPGEF1, CXCL1, HIST1H2AE, HMGA1, HRG, IFIT3, IGF1, IGFBP6, RBPJ, IHH, IL1A, IL1B, IL2RA, IL10, TNFRSF9, IDO1, ING1, ING2, INPPL1, INSL3, IRF1, ITGA1, ITGB1, JARID2, JUN, KCNK2, KISS1, SMAD1, SMAD3, SMAD6, FOXO4, NTRK1, OVOL1, PAWR, PHB, PRKAR1A, PRKCA, EIF2AK2, PROX1, PTHLH, PTH1R, PTPN6, PTPN14, PTPRJ, PTPRZ1, RAF1, RARA, RARB, RBBP4, REST, RPS6KA2, RXRA, S100A11, XCL1, SFRP4, SFRP5, SFTPD, SHH, SLC6A4, SLIT3, SMARCA2, SOD2, SOX4, SPINT1, SPN, SRF, SSTR2, SSTR3, STAT3, STRN, TAF6, KLF10, NR2E1, TP73, TSC1, TSC2, TSG101, SCGB1A1, VEGFC, WNT11, FZD5, AIMP2, FOSL1, CUL5, BAP1, SRPX, CUL4A, CUL2, CUL1, KLF11, PPM1D, PRKRA, PDE5A, BECN1, TRIM24, KAT2B, ALDH1A2, PHOX2B, IL1RL1, ITGB1BP1, CNOT8, CER1, SLIT2, SLC9A3R1, ADAMTS1, TP53I11, PHF14, RAPGEF2, HDAC4, DLEC1, FGFBP1, NR2E3, ABI1, PTPRU, RNF41, DHRS2, SPEG, IFI30, GPNMB, CHERP, PRDX4, SPINT2, CGRRF1, CGREF1, GJB6, COPS8, IL24, VAX1, PIM2, TMEM115, GLMN, WDR6, PTGDR2, B4GALT7, VSIG4 |
1113 | GO:0044706 | 0.01 | 3.42 | 7.01 | 12 | 17 | multi-multicellular organism process | ACVR2A, ARNTL, AVP, DBH, EDNRA, GNAQ, PTAFR, SEMG1, SLC6A4, TAC1, DDO, EDDM3A |
1114 | GO:0051781 | 0.00 | 3.42 | 20.00 | 34 | 48 | positive regulation of cell division | APC, BIRC5, CAT, CD28, EDN3, EREG, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, IGF1, IGF1R, IGF2, IL1A, IL1B, INS, YBX1, PGF, PTN, RB1, SHH, AURKA, TAL1, VEGFA, VEGFB, VEGFC, ZNF16, BECN1, ITGB1BP1, DLGAP5, UBE2C, PHB2 |
1115 | GO:0033138 | 0.00 | 3.41 | 20.03 | 34 | 48 | positive regulation of peptidyl-serine phosphorylation | AKT2, ANGPT1, AVP, BCL2, CD44, CDC42, CREBL2, GAS6, GCG, HCLS1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, NTF3, NTRK2, NTRK3, PFN2, PRKD1, RAF1, SNCA, UCN, VEGFA, BCAR3, CAMK1, RIPK2, LATS1, BAG4, AKAP9, RAPGEF3, MAD2L2 |
1116 | GO:0003206 | 0.00 | 3.41 | 10.00 | 17 | 24 | cardiac chamber morphogenesis | CAV3, COL11A1, DSP, GATA3, NRG1, HIF1A, RBPJ, RXRA, RYR2, SMARCD3, SRF, TNNC1, TNNI3, TNNT2, WNT2, HAND2, ADAMTS1 |
1117 | GO:0000186 | 0.00 | 3.41 | 56.76 | 96 | 136 | activation of MAPKK activity | ADORA1, ANGPT1, BMP4, CALM3, CAMK2A, CAMK2G, CSF2, CSF2RB, HBEGF, DUSP5, DUSP7, DUSP9, ERBB2, EREG, ERCC6, F2R, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FLT1, FYN, GRB2, RAPGEF1, GRIN2A, GRM1, NRG1, IL2RA, IL2RB, IL2RG, KIT, KRAS, MARK3, MAP3K5, KITLG, MAP3K11, NRAS, NTRK1, PEBP1, PPP5C, MAPK3, EIF2AK2, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPRA, RAF1, RAP1A, RASA2, RPS27A, SHC1, SOS1, SPTA1, SPTB, UBB, FGF23, CUL3, PEA15, ADAM9, TAOK2, PSMF1, CARTPT, RAPGEF2, PSMD6, RBX1, AKAP9, RASA4, PSME3, FRS3 |
1118 | GO:0010862 | 0.00 | 3.40 | 10.02 | 17 | 24 | positive regulation of pathway-restricted SMAD protein phosphorylation | ACVR1, ACVR1B, ACVR2A, ACVRL1, BMP1, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, DAB2, GDF9, INHA, SDCBP, BMP15, GDF15, RBPMS |
1119 | GO:0034394 | 0.00 | 3.40 | 10.02 | 17 | 24 | protein localization to cell surface | ANGPT1, ARF6, CAV3, EMP2, FCN1, FGF7, FLNA, GPM6B, NRG1, USP4, VCL, WNT11, KCNAB2, RAB11B, PIGK, PTPRU, FBLN5 |
1120 | GO:0042326 | 0.01 | 3.40 | 7.04 | 12 | 17 | negative regulation of phosphorylation | AHSG, RHOH, FOXA2, INHA, PRPSAP1, RANBP2, ATXN7, STAT3, DYNLL1, RUBCN, HDAC4, PRDX3 |
1121 | GO:0051437 | 0.00 | 3.39 | 24.21 | 41 | 58 | positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition | CCNB1, CDC20, CDC27, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SKP1, UBB, UBE2D1, CUL1, CDC23, CDC16, PSMF1, PSMD6, PSME3, ANAPC10, UBE2C |
1122 | GO:0042475 | 0.00 | 3.39 | 17.11 | 29 | 41 | odontogenesis of dentin-containing tooth | ACVR2B, AMBN, BAX, BMP4, BMPR1A, BSG, CA2, RUNX2, CHUK, ATF2, CTNNA1, DLX3, EDA, FGF8, TNC, ITGA6, ITGB4, LAMA5, TNFRSF11B, SCN5A, SCN10A, SHH, SLC34A1, IFT88, TP63, HAND1, HAND2, BCL2L11, EDAR |
1123 | GO:0031145 | 0.00 | 3.38 | 28.38 | 48 | 68 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | BUB1B, CCNB1, CDC20, CDC27, MAD2L1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SKP1, SKP2, AURKA, UBB, UBE2D1, CUL1, CDC23, CDC16, BUB3, AURKB, PSMF1, PSMD6, PSME3, ANAPC10, MAD2L2, UBE2C |
1124 | GO:1903169 | 0.02 | 3.38 | 7.07 | 12 | 17 | regulation of calcium ion transmembrane transport | BMP4, CACNB4, CAV3, PDE4B, PIK3CG, S100A1, SLC9A1, SUMO1, RGN, KCNE2, KCNE3, RAPGEF3 |
1125 | GO:0050818 | 0.00 | 3.37 | 21.28 | 36 | 51 | regulation of coagulation | ABAT, ADRB2, ALOX12, ANXA2, ANXA5, APOH, SERPINC1, SERPING1, CD36, F2R, F2RL1, F3, F7, F12, FAP, FCER1G, FGA, FGG, GP1BA, FOXA2, HRG, KLKB1, KNG1, KRT1, SERPINE1, PRKCA, PRKCQ, PRKG1, PROC, PROS1, S100A9, SELP, SYK, USF1, VTN, PROCR |
1126 | GO:0000184 | 0.00 | 3.37 | 32.55 | 55 | 78 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | EIF4G1, FAU, EIF3E, RPL10A, PPP2R1A, PPP2R2A, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, RPL14, RPL23, DHX34, CTIF, SMG7, RNPS1, RPL35 |
1127 | GO:0002286 | 0.02 | 3.37 | 7.08 | 12 | 17 | T cell activation involved in immune response | F2RL1, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, ITGAL, RAB27A, SLC11A1, STX11 |
1128 | GO:0031295 | 0.00 | 3.37 | 14.19 | 24 | 34 | T cell costimulation | CD3D, CD3G, CD4, CD5, CD28, CD80, CD86, CDC42, CTLA4, DPP4, EFNB2, FYN, GRB2, HLA-DQA1, PDPK1, PTPN6, RAC1, CCL21, SPN, TNFSF4, VAV1, TNFSF14, TNFSF13B, HHLA2 |
1129 | GO:0033692 | 0.00 | 3.37 | 14.19 | 24 | 34 | cellular polysaccharide biosynthetic process | AKT2, EXT1, EXT2, GYS2, HAS1, HAS2, HAS3, IGF1, IGF2, INS, ENPP1, PGM1, PHKG1, PPP1CA, PPP1R3C, RPS27A, UBB, UGP2, EPM2A, DYRK2, NR1D1, EPM2AIP1, B3GNT3, SORBS1 |
1130 | GO:0050432 | 0.02 | 3.36 | 7.09 | 12 | 17 | catecholamine secretion | ABAT, ADRA2C, AGTR2, CNR1, FFAR3, KCNA2, P2RY1, PARK2, PTGS1, SNCA, CADPS, HRH3 |
1131 | GO:1902656 | 0.00 | 3.36 | 25.46 | 43 | 61 | calcium ion import into cytosol | ATP1A2, BAX, CALM3, CASQ2, CCR5, CYBA, DIAPH1, EDNRA, F2R, XCR1, GSTM2, HRC, HTR2C, IL13, ITPR1, ITPR2, ITPR3, NTSR1, P2RX7, PDE4D, PDPK1, PLN, PRKACA, PRKCE, PRKD1, PTPN6, RYR1, RYR2, RYR3, CCL21, XCL1, SLC8A1, SNCA, TRPC1, TRPM2, TRPV1, HAP1, GSTO1, AKAP6, ATG5, TRDN, CHERP, CORO1A |
1132 | GO:0001964 | 0.02 | 3.36 | 7.09 | 12 | 17 | startle response | CTNNA2, FABP7, GLRA1, GLRB, GRID2, GRIN2A, NRG1, KCNA1, PARK2, PENK, UCN, NRXN1 |
1133 | GO:0002639 | 0.02 | 3.36 | 7.09 | 12 | 17 | positive regulation of immunoglobulin production | CD28, CD37, CD40, HPX, IFNG, IL13, XCL1, TNFSF4, TNFRSF4, UNG, WHSC1, TNFSF13 |
1134 | GO:0014911 | 0.02 | 3.36 | 7.09 | 12 | 17 | positive regulation of smooth muscle cell migration | BCL2, LPAR1, F3, HAS2, IGF1, ITGA2, P2RY2, P2RY6, PTGER4, VTN, HDAC4, RAPGEF3 |
1135 | GO:0030811 | 0.02 | 3.36 | 7.09 | 12 | 17 | regulation of nucleotide catabolic process | ARNT, GPD1, HIF1A, IGF1, INS, P2RX7, PRKAA1, STAT3, OGT, HDAC4, RAPGEF3, ECD |
1136 | GO:0043094 | 0.02 | 3.36 | 7.09 | 12 | 17 | cellular metabolic compound salvage | ADA, ADK, AMPD1, AMPD2, APRT, BHMT, CDA, TYMP, GOT1, HPRT1, UPP1, PDXK |
1137 | GO:0048025 | 0.02 | 3.36 | 7.09 | 12 | 17 | negative regulation of mRNA splicing, via spliceosome | C1QBP, DYRK1A, PTBP1, SRSF4, SRSF6, SRSF7, SFSWAP, SRSF9, PTBP3, SAP18, SRSF10, RNPS1 |
1138 | GO:2000516 | 0.02 | 3.36 | 7.09 | 12 | 17 | positive regulation of CD4-positive, alpha-beta T cell activation | ANXA1, CD80, CD86, CD55, HLX, IFNG, PRKCQ, PRKCZ, RARA, XCL1, TNFSF4, RIPK2 |
1139 | GO:0050852 | 0.00 | 3.36 | 33.77 | 57 | 81 | T cell receptor signaling pathway | CACNB4, CD3D, CD3G, CD4, CD28, CHUK, FYB, FYN, GATA3, HLA-DQA1, PDE4B, PDE4D, PDPK1, PIK3CB, PRKCQ, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SKP1, STK11, UBB, UBE2D1, UBE2D2, UBE2V1, CUL1, IKBKG, RIPK2, THEMIS2, PSMF1, BCAR1, PSMD6, PSME3, RBCK1 |
1140 | GO:0051436 | 0.00 | 3.36 | 29.63 | 50 | 71 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | APC, ATM, BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, DUSP1, MAD2L1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, UBB, UBE2D1, ZNF207, CDC23, CDC16, ZW10, BUB3, PSMF1, PSMD6, PSME3, ANAPC10, MAD2L2, UBE2C |
1141 | GO:0044724 | 0.00 | 3.35 | 22.49 | 38 | 54 | single-organism carbohydrate catabolic process | ALDOB, ALDOC, ARNT, BAD, BPGM, ENO2, FUT6, FUT8, GALE, GALK1, GAPDH, GLB1, GM2A, GPD1, HEXB, HIF1A, HK2, IGF1, KHK, LDHA, OGDH, P2RX7, PFKFB2, PFKFB4, PGAM2, PGK1, PGK2, PPP2R5D, PRKAA1, RPE, STAT3, OGT, HDAC4, XYLB, AKR1A1, FUT9, TREH, ECD |
1142 | GO:0033077 | 0.00 | 3.34 | 11.25 | 19 | 27 | T cell differentiation in thymus | APC, BCL2, ZFP36L2, CD3D, CD28, CD74, CDK6, GATA3, ITPKB, RAG1, RAG2, SPN, SRF, STAT5B, STK11, WNT1, FZD5, FZD7, FZD8 |
1143 | GO:0071417 | 0.00 | 3.33 | 126.54 | 212 | 306 | cellular response to organonitrogen compound | ADCY1, ADCY3, ADCY7, ADCY9, AHSG, AKT2, ALDOB, ANGPT1, ANXA5, APRT, ARG1, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, CALM3, CAMK2A, CAMK2G, CASP4, CAV2, CDC5L, CDC6, CISH, AP3S1, CSF2, CSF2RB, CSH1, CYP11B1, DIAPH1, HBEGF, DUSP5, DUSP7, DUSP9, EIF4B, EIF4E, EIF4EBP1, EIF4EBP2, EIF4G1, ERBB2, EREG, FBN1, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FYN, GABRB2, GCG, GCGR, GH2, GHRHR, GHSR, GLP1R, GNB2, GNRHR, GOT1, GPLD1, FFAR3, GRB2, GRIN2A, NRG1, HIF1A, HMBS, NR4A1, HRH1, IDE, IGF1, IGF1R, IGF2, IL1B, IL2RA, IL2RB, IL2RG, INS, KIT, KRAS, MARK3, RAB8A, MEN1, KITLG, FOXO4, NRAS, YBX1, P2RX4, P2RY2, P2RY11, PEBP1, PDE3B, PDK4, ENPP1, PDPK1, PIK3C2A, PIK3C3, PIK3CB, PPM1A, PPP5C, PRKAA1, PRKAB2, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCB, PRKCI, PRKCQ, PRKCZ, MAPK3, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN1, PTPN6, PTPRA, PTPRE, RAB13, RAF1, RASA2, RHEB, RPS6, RPS27A, RXRA, SRSF5, SHC1, SHMT1, SLC2A4, SMARCC1, SOD1, SOS1, SOX9, SPTA1, SPTB, SREBF1, SSTR2, SSTR3, STAT3, STAT5B, STK11, KLF10, TSC1, TSC2, UBB, UROS, USF1, WNT1, YWHAG, FGF23, CUL3, IRS4, OGT, PIK3R3, PEA15, RIPK2, KAT2B, ATP6V0E1, SOCS3, ATP6V0D1, IL1RL1, ARHGEF2, ATP6V1F, KLF4, GLP2R, SLIT2, PSMF1, ATP6V1G1, BCAR1, C2CD5, PSMD6, NR1H4, RBX1, RASA4, PSME3, KLF2, BAIAP2, CIB2, SORBS1, SH2B2, KLF1, FRS3, RAB31, CAPN10 |
1144 | GO:0051602 | 0.00 | 3.33 | 11.27 | 19 | 27 | response to electrical stimulus | ADSS, CD14, DCX, EEF1A2, GNAT1, GRM1, HIF1A, IGF1, KCNJ3, NRF1, NTRK1, OXT, P2RX7, RAB3A, REST, S100A13, SLC9A1, TACR2, GJB6 |
1145 | GO:0032388 | 0.00 | 3.32 | 16.57 | 28 | 40 | positive regulation of intracellular transport | AKT2, BAD, BCL2, BID, CASP8, CDC42, CDK5, CHRM1, DNM1, STOM, ERBB2, OAZ1, OAZ2, PCM1, MAPK8, SCP2, YWHAG, YWHAH, YWHAZ, DYNLL1, SYNJ1, ITGB1BP1, C2CD5, BCL2L11, UNC13B, SIVA1, EHD1, CAPN10 |
1146 | GO:0000082 | 0.00 | 3.32 | 29.06 | 49 | 70 | G1/S transition of mitotic cell cycle | ACVR1, ACVR1B, BACH1, BCAT1, BID, CAMK2A, CAMK2G, CCNB1, CCNE1, CCNH, CDK3, CDK4, CDK6, CDKN2A, CDKN2C, CDKN2D, CKS1B, DHFR, E2F4, EIF4E, EIF4EBP1, GFI1, ITGB1, ORC1, ORC2, ORC5, PIM1, PPP6C, PRIM1, PRIM2, PTPN6, RBBP8, RPA3, RRM2, SKP1, SKP2, TYMS, WEE1, CUL5, CUL3, CUL2, CUL1, KLF11, LATS1, CCNE2, PDPN, DBF4, PIM2, ECD |
1147 | GO:0070301 | 0.00 | 3.32 | 15.44 | 26 | 37 | cellular response to hydrogen peroxide | ANXA1, AQP1, ARG1, BNIP3, ECT2, ETS1, F3, HGF, HIF1A, MAP3K5, PAX2, PPP5C, PRKAA1, MAPK8, PYCR1, RPS3, TNFAIP3, IL18RAP, AIFM1, KLF4, HDAC6, IL18BP, TRAP1, KLF2, STK25, ZNF277 |
1148 | GO:0019058 | 0.00 | 3.31 | 46.24 | 78 | 112 | viral life cycle | DDX6, FAU, HSP90AB1, KPNA1, KPNB1, KPNA4, KPNA5, RPL10A, NUP88, NUP98, CHMP1A, PCSK5, RAB1A, RAN, RANBP2, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, UBB, USF1, USF2, RAB7A, NUP214, AAAS, RPL14, RPL23, ATG5, NUP155, NUP93, USP6NL, IST1, PDCD6IP, ALYREF, ATG7, CXCR6, NUP50, CPSF4, NUPL2, RPL35 |
1149 | GO:0046364 | 0.00 | 3.31 | 23.79 | 40 | 57 | monosaccharide biosynthetic process | ALDOB, ALDOC, ATF3, ATF4, BPGM, CRY1, SLC25A10, ENO2, G6PC, GAPDH, GCG, KAT2A, GOT1, GOT2, GPD1, GPD2, INS, MDH1, MDH2, PCK1, PCK2, PGAM2, PGD, PGK1, PGM1, PRKACA, PRKACB, PRKACG, RANBP2, SLC25A1, SORD, OGT, KAT2B, RGN, GSTO1, NR1D1, SLC25A13, AKR1A1, ARPP19, SDS |
1150 | GO:0048871 | 0.00 | 3.31 | 21.89 | 37 | 53 | multicellular organismal homeostasis | ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ALOX12, AMPD2, AQP1, AVP, AVPR2, BMP6, CD36, FLG, SFN, HAS2, KRT16, SLC11A2, PRCP, PRKAA1, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, RHAG, SCNN1A, SCNN1B, SCNN1G, SLC11A1, UBB, WFS1, CYP4F2, TP63, RAB11A, NR1D2 |
1151 | GO:0051240 | 0.00 | 3.31 | 83.05 | 141 | 206 | positive regulation of multicellular organismal process | ABAT, ACVR1, ACVR1B, ACVR2A, ACVR2B, ACVRL1, ADK, ALB, ANGPT2, APOC2, APOH, ARNTL, ATP2A1, ATP6AP1, AXL, BAD, BAX, CCND1, PRDM1, BMP1, BMPR1A, BTG1, BTK, CA2, CASP8, RUNX2, CBLB, CCNB1, CDC42, CDK9, CHI3L1, CHRM3, CCR1, CCR3, COL1A1, CTH, CYP27B1, DAB2, DLX5, ECM1, EFNB2, EGR3, CTTN, EPHA1, ERG, F3, F7, F12, FLT1, FLT3LG, GALR1, GAS6, GATA6, B4GALT1, GNAS, SFN, GPC1, GPM6B, HCLS1, HLX, HMGCR, HPN, HRG, PRMT1, RBPJ, IHH, IL2RA, INHA, ITGA5, ITPKB, JUND, KISS1, LTF, SMAD1, KITLG, DDR2, PDE3A, PENK, PGF, PRKAA1, PRKCB, MAPK8, PTCH1, PTGIS, RAG1, RAG2, RB1, RFX3, RPS19, RRAS, S100A9, SERPINB3, CCL24, SDCBP, SELP, SFRP4, SRSF6, SLC8A1, SLC9A1, SNAI1, SOX5, AURKA, TACR2, TAL1, KLF10, NR2E1, TNFAIP3, TRPC3, UNG, USF1, VDR, VEGFB, WHSC1, ZIC2, ZNF16, FOXN1, OGT, AP3B1, TNFSF11, TP63, PTCH2, PDE5A, VAMP8, TRADD, TNFSF13, TNFSF12, VNN1, AP3D1, USP2, PDLIM7, LIPG, GSTO1, HAND2, AKAP6, ZEB2, TRIB1, RAMP2, TRDN, ABCA7, RAPGEF3, OLFM1 |
1152 | GO:0045785 | 0.00 | 3.31 | 58.94 | 99 | 142 | positive regulation of cell adhesion | ADA, ADK, ALOX12, ANGPT1, ANXA1, APC, BAD, CD3D, CD3G, CD4, CD5, CD6, CD28, CD80, CD86, CD44, CD59, CD63, CD74, CTLA4, CD55, DHPS, DPP4, EFNB2, EGR3, ERBB2, FLOT2, FYN, GATA3, GRB2, NRG1, HLA-DQA1, HLX, FOXA2, HES1, IFNG, IGF1, IGF2, IGFBP2, IHH, IL1B, IL2RA, IL18, ITGA6, ITGA2, ITGA4, ITGAL, ITGAV, ITPKB, SMAD7, CD46, PAWR, PDPK1, PRKCA, PRKCQ, PTAFR, PTGER4, PTPN6, RAG1, RAP1GAP, RARA, XCL1, CX3CL1, SELP, SHH, SOX2, SPN, SPTA1, STAT5B, SYK, TRAF2, TNFSF4, VAV1, ZP3, AP3B1, TNFSF11, CHRD, TNFSF14, TNFSF9, ADAM9, RIPK2, TNFRSF18, IL1RL2, VNN1, BCL10, AP3D1, TNFSF18, CYTH3, BAG4, EBI3, FSTL3, IKZF1, CITED2, VAV3, CXCL13, TNFSF13B, MALT1, HHLA2, CORO1A |
1153 | GO:0001894 | 0.01 | 3.30 | 8.29 | 14 | 20 | tissue homeostasis | BARD1, COL2A1, COL9A1, CTGF, FGF7, GNAS, ITGB1, KDR, P2RX4, PTHLH, SFTPD, STK11, VEGFA, CUBN |
1154 | GO:0043406 | 0.01 | 3.30 | 8.29 | 14 | 20 | positive regulation of MAP kinase activity | CD40, EDN3, ERBB2, FGF1, FLT1, FLT3, ILK, KRAS, KITLG, PIK3CG, S100A12, TPD52L1, VEGFA, PDE5A |
1155 | GO:1901701 | 0.00 | 3.29 | 131.59 | 221 | 323 | cellular response to oxygen-containing compound | ADCY9, AHSG, AKT2, ALDOB, ANGPT1, ANXA5, APLP1, APRT, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, BAD, CACNA1E, CALM3, CAMK2A, CAMK2G, CASP4, CAV2, CDC6, AKR1C4, CISH, AP3S1, CSF2RB, CSH1, CYP11B1, HBEGF, DUSP5, DUSP7, DUSP9, LPAR1, EFNA5, EIF4B, EIF4E, EIF4EBP1, EIF4EBP2, EIF4G1, SLC29A1, EPHA5, ERBB2, EREG, ERN1, FBN1, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FYN, GATA4, GCG, GCGR, GH2, GHRHR, GHSR, GLP1R, GNB2, GNRHR, GOT1, GPR27, GRB2, GRIN2A, NRG1, HMGCR, NR4A1, FOXA2, IDE, IGF1R, IGF2, IL1R1, IL2RA, IL2RB, IL2RG, INS, KCNJ11, KIT, KRAS, MARK3, RAB8A, MEN1, KITLG, FOXO4, NRAS, YBX1, OXCT1, P2RX4, P2RY11, PEBP1, PARK2, CDK16, PDE3B, ENPP1, PDPK1, PIK3C2A, PIK3C3, PIK3CB, PPM1A, PRKAB2, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCB, PRKCI, PRKCQ, PRKCZ, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN1, PTPN6, PTPRA, PTPRE, PTPRN, PTPRN2, RAB13, RAF1, RASA2, RHEB, RPS6, RPS6KA2, RPS27A, RXRA, RYR2, RYR3, SRSF5, SHC1, SHMT1, SIPA1, SLC2A4, SLC2A5, SLC9A1, SMARCA4, SMARCC1, SNCA, SOS1, SOX4, SPTA1, SPTB, SRF, STAT3, STAT5B, STK11, KLF10, TSC1, TSC2, UBB, USF1, TRPV1, VSNL1, WNT1, YWHAG, ZNF16, CUL3, IRS4, PIK3R3, PEA15, KAT2B, ATP6V0E1, SOCS3, ATP6V0D1, IL1RL1, ARHGEF2, RAB11B, ATP6V1F, HMGN3, GLP2R, SLIT2, NRXN1, PSMF1, ATP6V1G1, BCAR1, C2CD5, C2CD2L, PSMD6, RBX1, RASA4, PSME3, CALCRL, BAIAP2, CIB2, SORBS1, SH2B2, KLF1, CERS1, GJB6, FRS3, RAB31, CAPN10, CHEK2 |
1156 | GO:0031668 | 0.00 | 3.29 | 47.16 | 79 | 113 | cellular response to extracellular stimulus | AES, ALB, ALDOB, ASGR1, ASNS, ATF3, ATF4, ATP2B1, AXL, BCL2, BGLAP, BMPR2, CBS, CCNE1, CDKN1A, COL1A1, COMT, CTSV, CYP24A1, CYP27B1, DSC2, EIF2S1, GAS6, GLUL, FOXA2, HSPA8, TNC, ICAM1, IFI16, ITGA6, ITGB1, JUN, LDHA, NUDT1, P2RX7, PAWR, PCK1, CHMP1A, PDK4, PENK, PIK3C3, PIM1, PRKAA1, EIF2AK2, PTN, RHAG, RHCE, RHD, SIPA1, SKP2, SNAI2, SRD5A1, SREBF1, SRF, KLF10, TSC1, UPP1, USF1, USF2, VDR, WNT2B, WRN, FOSL1, FGF23, PPM1D, AKR1C3, BECN1, TRIM24, AIFM1, EIF2AK3, PICK1, ATG5, ADAMTS1, CARTPT, NR1H4, ATG7, GAS2L1, RRAGA, SLC38A3 |
1157 | GO:0031326 | 0.00 | 3.29 | 33.87 | 58 | 85 | regulation of cellular biosynthetic process | ABCA1, ACTN4, ACTN1, ADCY7, ADCYAP1R1, ADORA2A, ASIP, ASS1, AVPR2, C3, CALCR, CALM3, SCARB1, CDH3, DLD, DTX1, ACSL3, FSHR, GHRH, GHRHR, GLP1R, GNAL, GNAS, GPLD1, FFAR3, GUCA1A, GUCA1B, GUCA2A, GUCA2B, HPN, HRH1, HSP90AA1, HSP90AB1, HTR2C, IDH1, INSL3, NTRK2, NTSR1, P2RX4, P2RY11, PTGER4, PTH1R, RCVRN, SMPD2, TYRP1, VIP, VIPR2, TRPV1, PDHX, NSMAF, AIP, TRIP11, GUCA1C, CALCRL, RAMP2, CAP2, CAP1, ARPP19 |
1158 | GO:0042060 | 0.00 | 3.28 | 18.20 | 31 | 45 | wound healing | ACVRL1, AQP1, BMP4, CAV3, SCARB1, CDH3, COL5A1, DCN, DSP, ELK3, ERBB2, EREG, FGF7, NRG1, TNC, IL1B, INS, ITGA9, P2RY2, PTK7, S100A8, SCNN1B, CCL20, SDC1, SDC2, SDC4, SLC11A1, SPRR3, DYSF, SYT7, IL24 |
1159 | GO:1904064 | 0.01 | 3.28 | 8.32 | 14 | 20 | positive regulation of cation transmembrane transport | ACTN4, ARF1, BAX, EDNRA, F2R, IL13, PDPK1, RYR2, XCL1, SLC9A1, SNCA, TRPC1, SUMO1, RGN |
1160 | GO:0048011 | 0.00 | 3.28 | 98.49 | 164 | 236 | neurotrophin TRK receptor signaling pathway | ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADCYAP1R1, ADORA2A, ADRBK1, AP2A1, AP2B1, AGTR2, ANGPT1, ARHGAP4, BAD, CALM3, CAMK4, CAMK2A, CAMK2G, CASP9, CD28, CD80, CD86, CDKN1A, CHUK, AP2M1, AP2S1, CLTA, CSF2, CSF2RB, HBEGF, DUSP4, DUSP5, DUSP7, DUSP9, ECT2, ELK1, ERBB2, EREG, FGD1, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FYN, GRB2, RAPGEF1, GRIN2A, NRG1, NR4A1, IL2RA, IL2RB, IL2RG, IRAK1, ITPR1, ITPR2, ITPR3, KIT, KRAS, MARK3, KITLG, FOXO4, NRAS, NTRK1, NTRK2, PEBP1, PCSK6, PCSK5, PDE1B, PDPK1, PIK3CB, PPP2R5D, PPP5C, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCE, PRKCG, PRKCI, MAPK3, MAPK8, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPRA, RAC1, RAF1, RALA, RAP1A, RASA2, RPS6KA1, RPS6KA2, RPS6KA3, RPS6KB2, RPS27A, SORT1, ITSN1, SHC1, SMPD2, SOS1, SOS2, SPTA1, SPTB, STAT3, TRIO, TSC2, UBB, VAV1, FGF23, CUL3, PEA15, RIPK2, HDAC3, ARHGEF7, KALRN, HAP1, ARHGEF2, RPS6KA5, ARHGEF6, PSMF1, BCAR1, RAPGEF2, ARHGEF17, PSMD6, RBX1, BCL2L11, AKAP9, RASA4, PSME3, VAV3, SLC9A6, FRS3, AKAP13 |
1161 | GO:0019229 | 0.01 | 3.28 | 8.33 | 14 | 20 | regulation of vasoconstriction | ATP1A2, BDKRB2, BMPR2, CHRM1, CHRM3, ACE, EDN2, EDN3, HIF1A, KCNA5, PRKCQ, CX3CL1, SNTA1, KCNMB2 |
1162 | GO:0033555 | 0.01 | 3.28 | 8.33 | 14 | 20 | multicellular organismal response to stress | ACP5, ADCYAP1R1, BCL2, CCK, DBI, DPP4, EIF4E, EIF4G1, HMGCS2, HTR2C, IDO1, PENK, NR2E1, DEAF1 |
1163 | GO:0009060 | 0.01 | 3.28 | 8.33 | 14 | 20 | aerobic respiration | ADSL, BNIP3, CAT, COX4I1, BLOC1S1, HIF1A, OXA1L, SURF1, UCN, UQCRB, UQCRC1, UQCRC2, UQCRH, SLC25A14 |
1164 | GO:0030500 | 0.01 | 3.27 | 8.34 | 14 | 20 | regulation of bone mineralization | AHSG, BGLAP, CCR1, CYP27B1, ECM1, S1PR1, HIF1A, DDR2, OMD, ENPP1, SRGN, SOX9, TWIST1, FGF23 |
1165 | GO:1903530 | 0.04 | 3.27 | 5.30 | 9 | 13 | regulation of secretion by cell | CD40, CRP, GJA5, KCNA2, LLGL2, PAM, PIK3C3, TRAF2, ATG5 |
1166 | GO:1990090 | 0.01 | 3.27 | 8.34 | 14 | 20 | cellular response to nerve growth factor stimulus | APC, CDC5L, CSNK1D, DNMT1, EEF2, KAT2A, NTRK2, NTS, RPS3, TAC1, TRPV1, EHD1, RAB35, STMN2 |
1167 | GO:0097006 | 0.00 | 3.27 | 12.52 | 21 | 30 | regulation of plasma lipoprotein particle levels | ABCA1, APOA1, APOA4, APOC2, ARF1, CD36, SCARB1, CETP, ACSL3, FECH, GPLD1, LCAT, LRPAP1, NR1H2, SOAT2, DGAT1, LIPG, ABCG1, NR1H4, ABCA7, EHD1 |
1168 | GO:2001238 | 0.00 | 3.27 | 12.52 | 21 | 30 | positive regulation of extrinsic apoptotic signaling pathway | AGTR2, ATF3, BAX, BID, CASP8, CTNNA1, CYLD, MAL, PPP1CA, PPP2R1A, PPP2R1B, SIGLEC1, TRAF2, TRPS1, SRPX, PEA15, RIPK1, TNFSF12, TNFSF10, BCL10, RBCK1 |
1169 | GO:0030521 | 0.01 | 3.27 | 8.34 | 14 | 20 | androgen receptor signaling pathway | BRCA1, CCNE1, DDX5, EP300, PRMT2, SCGB2A1, RAN, RB1, RNF6, UBE3A, NRIP1, BUD31, NR1I3, HDAC6 |
1170 | GO:0072521 | 0.00 | 3.27 | 14.81 | 25 | 36 | purine-containing compound metabolic process | AOX1, ATP2B2, CACNB4, CAT, DPYD, G6PC, GPX1, IL1B, NUDT1, OGG1, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, PF4, VEGFA, PDE5A, ABCG2, RAPGEF3, PDE10A |
1171 | GO:0001975 | 0.01 | 3.27 | 8.35 | 14 | 20 | response to amphetamine | ADRA1B, CALM3, CNR2, DBH, TRDMT1, GNAL, GRIN2A, HPRT1, ICAM1, NTS, OXT, PDE1B, RANBP2, SOD1 |
1172 | GO:0006271 | 0.01 | 3.27 | 8.35 | 14 | 20 | DNA strand elongation involved in DNA replication | FEN1, PRIM1, PRIM2, RFC1, RFC2, RFC3, RFC4, RFC5, RPA3, CDC45, GINS1, PARP2, PARP3, RNASEH2A |
1173 | GO:0033014 | 0.01 | 3.27 | 8.35 | 14 | 20 | tetrapyrrole biosynthetic process | ALAD, ALAS1, ALAS2, TSPO, COX15, CPOX, FECH, HMBS, SLC11A2, SPTA1, SPTB, UROS, SUCLA2, ABCB6 |
1174 | GO:0040019 | 0.01 | 3.27 | 8.35 | 14 | 20 | positive regulation of embryonic development | GATA3, GDNF, FOXA2, HES1, IGF1, OTX2, SHH, SIX1, NR2C2, WNT1, WNT2, WNT2B, RBM19, DMRT2 |
1175 | GO:0042168 | 0.01 | 3.27 | 8.35 | 14 | 20 | heme metabolic process | ALAD, ALAS1, ALAS2, AMBP, BLVRA, BLVRB, TSPO, COX15, CPOX, FECH, HMBS, HPX, SLC11A2, UROS |
1176 | GO:0043300 | 0.01 | 3.27 | 8.35 | 14 | 20 | regulation of leukocyte degranulation | AP1G1, F2RL1, FCER1A, FCER1G, FGR, IL13, PDPK1, PTAFR, RAC2, STXBP2, SYK, VAMP8, CD84, GAB2 |
1177 | GO:0045124 | 0.01 | 3.27 | 8.35 | 14 | 20 | regulation of bone resorption | ATP6AP1, BGLAP, CA2, CD38, S1PR1, IAPP, TNFRSF11B, P2RX7, PDK4, PTGER4, SYK, TNFAIP3, TNFSF11, CARTPT |
1178 | GO:0038093 | 0.00 | 3.26 | 14.83 | 25 | 36 | Fc receptor signaling pathway | ACTB, ACTG1, CD3G, CDC42, FCGR1B, FCGR2A, FCGRT, FGR, HCK, HSP90AA1, HSP90AB1, LIMK1, PIGR, PRKCE, ELMO1, ABI1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, WASF2, BAIAP2, ARPC1A |
1179 | GO:0072329 | 0.00 | 3.26 | 26.29 | 44 | 63 | monocarboxylic acid catabolic process | ABAT, ACAA1, ACADL, ACADM, ACADS, ACADSB, ACADVL, ACOX1, AGXT, AKT2, ABCD1, CNR1, CPT1B, CPT2, DECR1, ECH1, EHHADH, ETFA, ETFDH, FAAH, GOT2, HADHA, HSD17B4, IDUA, IVD, LIPE, PCCA, ABCD3, SCP2, SORD, SULT2A1, TWIST1, ACOX2, ACOX3, CYP4F2, ALDH4A1, XYLB, ACOT8, AKR1A1, ECI2, SLC25A17, SLC27A4, SLC27A2, ACOT7 |
1180 | GO:0050867 | 0.00 | 3.26 | 61.76 | 103 | 148 | positive regulation of cell activation | ADA, ADK, AP1G1, ANXA1, AXL, BAD, BCL2, PRDM1, BTK, CD2, CD3D, CD3G, CD4, CD5, CD6, CD28, CD80, CD86, CD38, CD40, CD59, CD74, CDC42, CDKN1A, CHRNB2, CTGF, CTLA4, CD55, DHPS, DPP4, GPR183, EFNB2, EGR3, F2RL1, FCER1A, FCER1G, FGR, FLOT2, FLT3LG, FYN, GAS6, GATA3, GRB2, HLA-DQA1, HLX, HES1, IFNG, IGF1, IGF2, IGFBP2, IHH, IL1B, IL2RA, IL13, IL18, ITGAL, ITPKB, CD46, PDPK1, PRKCQ, PRKCZ, PTAFR, PTPN6, RAC1, RAG1, RARA, RPS6KA1, CCL21, XCL1, SELP, SHH, SPN, SPTA1, STAT5B, SYK, TAC1, TRAF2, TNFSF4, TNFRSF4, UNG, VAV1, WHSC1, ZP3, AP3B1, TNFSF11, VAMP8, TNFSF14, TNFSF13, TNFSF9, RIPK2, IL1RL2, VNN1, BCL10, AP3D1, IL1RL1, GAB2, EBI3, IKZF1, VAV3, TNFSF13B, MALT1, HHLA2, CORO1A |
1181 | GO:0072091 | 0.00 | 3.25 | 22.12 | 37 | 53 | regulation of stem cell proliferation | ARHGAP5, BMP4, BMPR1A, CTNNA1, CX3CR1, ACE, FBLN1, FGF9, HIF1A, IHH, KDR, EPCAM, KITLG, OVOL1, PRRX1, EIF2AK2, PTN, CX3CL1, SHH, SIX1, SIX3, SNAI2, SMARCD3, SOX2, SOX9, SOX10, SOX11, NR2E1, VEGFA, VEGFC, WNT2, WNT11, FZD3, TP63, CHRD, PHF14, VAX1 |
1182 | GO:1903555 | 0.00 | 3.25 | 22.12 | 37 | 53 | regulation of tumor necrosis factor superfamily cytokine production | ACP5, ANGPT1, AXL, BCL3, BPI, TSPO, CD2, CD14, CD86, TNFRSF8, CD36, CLU, CYBA, FCER1G, GAS6, GHSR, HSPB1, IFNG, IL10, ISL1, LTF, PF4, PTAFR, PTGER4, RARA, SLAMF1, SPN, TNFAIP3, TWIST1, ZFP36, RIPK1, RIPK2, ARHGEF2, NR1H4, SPON2, GPNMB, ARFGEF2 |
1183 | GO:0042552 | 0.00 | 3.25 | 17.93 | 30 | 43 | myelination | AKT2, CD9, CLU, LPAR1, EGR2, ERBB2, FGFR3, GPC1, HEXB, ILK, KCNJ10, MAL, NTF3, KLK6, SCN8A, SLC8A3, SOD1, CNTN2, TSC1, UGT8, XK, ATRN, CNTNAP1, EIF2B4, EIF2B2, EIF2B5, QKI, GAL3ST1, TSPAN2, OLIG2 |
1184 | GO:0050778 | 0.00 | 3.24 | 17.17 | 29 | 42 | positive regulation of immune response | ANXA1, CD80, CD40, CD74, CTSG, FFAR3, HLX, HRG, IFNG, IL13, IDO1, P2RX7, PRKCZ, PTAFR, RARA, XCL1, SLC11A1, TRAF2, TNFSF4, UNG, WHSC1, FZD5, SEMA7A, VAMP8, TNFSF13, IL27RA, GAB2, SPON2, TNFSF13B |
1185 | GO:0007411 | 0.00 | 3.24 | 128.53 | 213 | 309 | axon guidance | ABL2, ACTB, ACTG1, ADAM10, AP2A1, AP2B1, ANGPT1, ATOH1, BMPR2, CACNA1S, CACNB4, CALM3, CAMK2A, CAMK2G, CD72, CDC42, AP2M1, AP2S1, CLTA, COL2A1, COL3A1, COL4A3, COL4A4, COL4A5, COL5A1, COL5A2, COL6A2, COL6A3, COL9A1, COL9A3, CSF2, CSF2RB, CSNK2A1, CSNK2A2, DCX, DLG1, DLG3, DLX5, DNM1, DPYSL3, HBEGF, DUSP5, DUSP7, DUSP9, EFNA1, EFNA3, EFNA4, EFNB2, EPHA2, EPHA1, EPHA3, EPHA5, EPHA8, EPHB2, EREG, ETV1, EXT1, FGF1, FGF3, FGF6, FGF7, FGF9, FGFR3, FGFR4, FYN, GAP43, GATA3, GDNF, GFRA1, GPC1, GRB2, GRIN2A, ARHGAP35, NRG1, HSPA8, HSP90AA1, HSP90AB1, IL2RA, IL2RB, IL2RG, ITGA1, ITGA2, ITGA5, ITGA9, ITGAV, ITGB1, KIF5A, KIT, KRAS, ABLIM1, LIMK1, MARK3, KITLG, NRAS, NRTN, NTF3, NTRK1, NTN3, OPHN1, OTX2, PEBP1, PPP5C, PRKCQ, MAPK3, PSPN, RELN, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPRA, RAC1, RAC2, RAF1, RASA2, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RRAS, RYK, SCN5A, SDC2, SDCBP, ITSN1, SHC1, SHH, SIAH1, SIAH2, SLIT3, SOS1, SOS2, SPTA1, SPTB, CNTN2, TNR, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, EZR, SEMA3B, FZD3, FGF23, CUL3, SEMA7A, CNTNAP1, KLF7, UNC5C, NUMB, PEA15, NRP2, ARHGEF7, RPS6KA4, KALRN, RPS6KA5, NRXN3, NRXN1, PSMF1, FEZ2, RAPGEF2, SEMA3E, FARP2, PSMD6, RBX1, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, PSME3, SPON2, VAV3, CAP2, CAP1, SEMA6C, SEMA6B, SEMA4B, ARPC1A, DPYSL4, TBR1, CHL1, FRS3, VAX1 |
1186 | GO:0045815 | 0.00 | 3.24 | 17.95 | 30 | 43 | positive regulation of gene expression, epigenetic | ACTB, EP300, ERCC6, KAT2A, H3F3B, HMGA1, PHF2, TBP, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, KAT2B, HIST1H3F, TAF1C, TAF1B, TAF1A, BAZ1B, DDX21 |
1187 | GO:1903779 | 0.00 | 3.24 | 17.95 | 30 | 43 | regulation of cardiac conduction | ATP1A2, ATP1B3, FXYD2, ATP2A1, ATP2B1, ATP2B2, CALM3, CASQ2, CXADR, GJA5, HRC, ITPR1, ITPR2, ITPR3, KCNJ11, PDE4D, FXYD3, PLN, PRKACA, RYR1, RYR2, RYR3, SLC8A1, SLC8A3, TNNI3, TRPC1, ABCC9, TRDN, CORIN, AHCYL1 |
1188 | GO:0051352 | 0.00 | 3.23 | 32.97 | 55 | 79 | negative regulation of ligase activity | APC, ATM, BUB1, BUB1B, CCNB1, CDC20, CDC27, CDKN2A, CENPF, DUSP1, LIMK1, MAD2L1, SMAD7, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, UBB, UBE2D1, ZNF207, CDC23, CDC16, RGN, ZW10, BUB3, PSMF1, BAG5, PSMD6, PSME3, ANAPC10, MAD2L2, UBE2C |
1189 | GO:0071453 | 0.00 | 3.23 | 32.97 | 55 | 79 | cellular response to oxygen levels | ADRB2, AQP1, ARNT, BACH1, BAD, BCL2, BDKRB2, BNIP3, BNIP3L, CCNB1, CLCA1, DNMT3A, DNMT3B, LPAR1, EIF4EBP1, SLC29A1, EP300, GATA6, GNB1, GNGT1, HIF1A, ICAM1, RBPJ, IRAK1, KCND2, KCNK2, KCNK3, PRKAA1, PRKCE, PTGIS, PTN, RPS27A, S100B, SLC2A4, SLC8A1, SLC8A3, SLC9A1, STC1, SUV39H1, TRPC1, TSC1, TWIST1, UBB, UBE2D1, UBE2D2, VEGFA, CUL2, OGT, AIFM1, PICK1, RBX1, CITED2, ACAA2, ATG7, USP19 |
1190 | GO:0006112 | 0.00 | 3.23 | 43.82 | 73 | 105 | energy reserve metabolic process | ACLY, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADRA1B, ADRA2C, AKT2, SLC25A4, ARL2, CACNA1A, CACNA1E, CALM3, CHRM3, CPS1, G6PC, GAA, GCG, GCGR, GLP1R, GNAS, GNB1, GNB2, FFAR1, GYS2, IGF1, IGF2, INS, ITPR1, ITPR2, ITPR3, KCNJ11, KCNS3, KHK, ENPP1, PGM1, PHKA2, PHKG1, PPP1CA, PPP1R1A, PPP1R2, PPP1R3C, PPP2R5D, PRKAB2, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PYGL, PYGM, RAP1A, RPS27A, SLC2A2, SNAP25, STK11, STXBP1, ABCC8, UBB, UGP2, EPM2A, DYRK2, IQGAP1, STBD1, NR1D1, EPM2AIP1, RAPGEF3, SORBS1, RAPGEF4 |
1191 | GO:0019886 | 0.00 | 3.23 | 23.37 | 39 | 56 | antigen processing and presentation of exogenous peptide antigen via MHC class II | AP2A1, AP2B1, AP1G1, ARF1, CD74, CENPE, AP2M1, AP1S1, AP2S1, CLTA, CLTC, CTSD, CTSE, CTSV, CTSS, DYNC1H1, DYNC1I1, DYNC1I2, DNM2, FCER1G, HLA-DQA1, KIF5A, KLC1, RAB7A, DYNLL1, CTSF, AP1S2, AP1M1, KIF3B, AP1M2, ACTR1B, ACTR1A, SEC24B, IFI30, SEC23A, DCTN6, SEC24A, KIF3A, DCTN3 |
1192 | GO:0010803 | 0.00 | 3.22 | 13.77 | 23 | 33 | regulation of tumor necrosis factor-mediated signaling pathway | BIRC3, APOA1, CASP8, CHUK, CYLD, F2RL1, GAS6, PARK2, RPS27A, SYK, TNFAIP3, TNFRSF1A, TRAF1, TRAF2, UBB, IKBKG, MADD, TRADD, RIPK1, TAX1BP1, CPNE1, TRAIP, RBCK1 |
1193 | GO:0032943 | 0.00 | 3.22 | 20.30 | 34 | 49 | mononuclear cell proliferation | AHR, BAX, CCND3, CD151, CLC, CR2, ACE, FLT3, FYN, HPRT1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IMPDH1, IMPDH2, IRF1, ITGAD, LMO1, CD180, P2RX7, PIK3CG, PSMB10, RAC2, RAG2, SATB1, SLC11A1, SOS1, SOS2, TNFSF14, TNFSF18, MALT1 |
1194 | GO:0002262 | 0.00 | 3.22 | 28.80 | 48 | 69 | myeloid cell homeostasis | ACVR1B, ACVR2A, ADAR, ADD1, ALAS2, ANXA1, ARNT, AXL, BAX, BMP4, CDK6, CEBPG, DNASE2, EPB42, ETS1, ETV2, FANCC, FCER1G, FECH, GATA3, HCLS1, HIF1A, PRMT1, IFNG, INHA, ITPKB, KIT, KITLG, SLC11A2, PDE4B, RB1, ARID4A, RHAG, RPS19, SOD1, SP1, SP3, SRF, STAT5B, TAL1, VEGFA, ZNF16, PTBP3, BCL2L11, IKZF1, KLF2, GAS2L1, KLF1 |
1195 | GO:0050821 | 0.00 | 3.22 | 28.80 | 48 | 69 | protein stabilization | APOA1, ATP1B3, CDKN2A, CLU, CREBL2, DSC3, EP300, FLNA, FLOT2, GAPDH, GNAQ, HIST1H1B, IGF1, LAMP2, SMAD3, SMAD7, PARK2, PEX6, PFN1, PFN2, PHB, PPIB, PEX19, SEL1L, SOX4, STXBP1, CCT3, TSC1, SUMO1, WFS1, ZNF207, USP13, USP2, BAG3, RASSF2, TSPAN1, IFI30, CRTAP, CCT7, CCT4, CCT2, CCT8, USP19, PIM2, CDC37, RASSF1, CHEK2, PHB2 |
1196 | GO:1900371 | 0.00 | 3.22 | 28.80 | 48 | 69 | regulation of purine nucleotide biosynthetic process | ABCA1, ADCY7, ADCYAP1R1, ADORA2A, ADRB2, APLP1, AVP, AVPR2, CALCR, CALM3, LPAR1, EDNRA, EDNRB, FSHR, GALR1, GCG, GHRH, GHRHR, GLP1R, GNAI3, GNAL, GNAS, GRM8, GUCA1A, GUCA1B, GUCA2A, GUCA2B, INSL3, NTRK1, NTRK2, P2RY11, PRKCA, PTGER4, PTHLH, RAF1, RCVRN, STAT3, UCN, VIP, VIPR2, WFS1, AKAP6, GABBR2, GUCA1C, CALCRL, RAMP2, CAP2, CAP1 |
1197 | GO:0051336 | 0.00 | 3.22 | 19.57 | 33 | 48 | regulation of hydrolase activity | EFNA5, ENSA, EPHA3, EPHA4, EPHA5, EPHA7, EPHB3, MGMT, NTRK2, OAS1, OAS3, PPP1R2, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PRKG1, EIF2AK2, SET, SLN, SNRNP70, SOD1, SOX2, DYNLT1, TNNC1, TPM2, TP63, CCPG1, ITGB1BP1, KIAA0141, NUAK1, ARPP19, BVES |
1198 | GO:0008286 | 0.00 | 3.22 | 77.11 | 128 | 185 | insulin receptor signaling pathway | AKT2, ANGPT1, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, CALM3, CAMK2A, CAMK2G, CAV2, AP3S1, CSF2, CSF2RB, HBEGF, DUSP5, DUSP7, DUSP9, EIF4B, EIF4E, EIF4EBP1, EIF4EBP2, EIF4G1, ERBB2, EREG, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FYN, GPLD1, GRB2, GRIN2A, NRG1, IDE, IGF1R, IGF2, IL2RA, IL2RB, IL2RG, INS, KIT, KRAS, MARK3, KITLG, FOXO4, NRAS, PEBP1, PDE3B, PDK4, PDPK1, PIK3C2A, PIK3C3, PIK3CB, PPM1A, PPP5C, PRKAA1, PRKAB2, MAPK3, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPRA, RAF1, RASA2, RHEB, RPS6, RPS27A, SHC1, SMARCC1, SOS1, SPTA1, SPTB, SREBF1, STK11, UBB, FGF23, CUL3, IRS4, OGT, PIK3R3, PEA15, ATP6V0E1, ATP6V0D1, ATP6V1F, PSMF1, ATP6V1G1, BCAR1, RAPGEF2, C2CD5, PSMD6, RBX1, AKAP9, RASA4, PSME3, BAIAP2, SORBS1, SH2B2, RRAGA, FRS3 |
1199 | GO:0010676 | 0.01 | 3.21 | 9.58 | 16 | 23 | positive regulation of cellular carbohydrate metabolic process | ADRA1B, AKT2, BAD, GCG, KAT2A, GPLD1, IGF2, PFKFB2, PRKCE, DYRK2, KAT2B, RGN, EPM2AIP1, SORBS1, ARPP19, DUSP12 |
1200 | GO:0098754 | 0.00 | 3.21 | 19.20 | 32 | 46 | detoxification | ALB, APOA4, CAT, CD36, DHFR, FANCC, GPX1, GPX2, GPX3, GPX7, GSTM1, GSTM2, GSTZ1, HBA1, HBA2, HP, MGST2, PTGS1, S100A9, SEPW1, SOD1, SOD2, PRDX2, SLC30A1, PXDN, EPX, RGN, GSTO1, PRDX6, FBLN5, PRDX4, PRDX3 |
1201 | GO:0040017 | 0.00 | 3.21 | 99.74 | 165 | 239 | positive regulation of locomotion | AAMP, ACP5, ACTN4, ACVR1, ACVR1B, ADAM10, AKT2, ALOX12, ANGPT1, ANXA3, APC, AQP1, ARHGAP5, BCL2, BMP4, BMPR2, C1QBP, SCARB1, CD74, CGA, CCR1, CMKLR1, COL1A1, CLDN7, DAB2, DIAPH1, HBEGF, S1PR1, LPAR1, EDN2, EDN3, EDNRA, EPHA1, ETS1, F2R, F2RL1, F3, F7, F10, FBLN1, FGF1, FGF7, FGR, FLT1, FLT4, GAS6, GATA3, GPLD1, GRB7, CXCL1, CXCL2, CXCL3, HAS2, HGF, HIF1A, ONECUT1, HSPB1, ICAM1, IFNG, IGF1, IGF1R, IL1B, ILK, INS, INSL3, ITGA2, ITGA3, ITGA4, ITGA5, ITGAV, ITGB1, JUN, KDR, KIT, EPCAM, SMAD3, KITLG, NTF3, NTRK3, DDR2, P2RY2, P2RY6, SERPINE1, PAWR, ENPP2, PF4, PF4V1, PFN1, PRKCA, PRKCE, PRKD1, PROX1, RELN, PTAFR, PTGER4, PTPRZ1, RAC1, RAC2, RDX, RREB1, SERPINB3, CCL20, CCL21, CCL24, CXCL6, CXCL5, XCL1, CX3CL1, SDCBP, SELE, SELP, SEMA3F, SLC8A1, SNAI2, SNAI1, SOX9, SPARC, TAC1, TMPRSS2, TRIP6, TWIST1, VEGFA, VEGFB, VEGFC, VIL1, VTN, WNT11, ZP3, PTP4A1, SCG2, SEMA3B, MADCAM1, SEMA7A, IKBKAP, NUMB, TNFSF14, ADAM9, RAB11A, TNFRSF18, NRP2, ARHGEF7, TNFSF18, ITGB1BP1, SLIT2, ONECUT2, BAG4, CXCL14, BCAR1, RAPGEF2, SEMA3E, HDAC4, HDAC6, PDCD6, SEMA3A, ATP8A1, RAPGEF3, TRIM38, CREB3, SEMA6C, SEMA6B, SEMA4F, SEMA4B, CXCL13, BVES, CORO1A |
1202 | GO:0007272 | 0.00 | 3.20 | 24.62 | 41 | 59 | ensheathment of neurons | AKT2, CD9, CLU, DLG1, LPAR1, EGR2, ERBB2, FGFR3, GPC1, HEXB, HGF, NRG1, IFNG, ILK, KCNJ10, MAL, NTF3, CLDN11, KLK6, RARA, RARB, RXRA, SCN8A, SLC8A3, SOD1, CNTN2, TSC1, UGT8, XK, ATRN, CNTNAP1, EIF2B4, EIF2B2, EIF2B5, QKI, EIF2AK3, GAL3ST1, FIG4, RNF10, TSPAN2, OLIG2 |
1203 | GO:0070374 | 0.00 | 3.20 | 35.47 | 59 | 85 | positive regulation of ERK1 and ERK2 cascade | ABL2, ANGPT1, ATP6AP1, BMP4, C3, CD36, CD44, CD74, CHI3L1, CCR1, CTGF, GPR183, EDNRA, ESR1, F2R, F2RL1, FGA, FGF1, FGF8, FGFR3, FGFR4, FGG, FLT4, FSHR, GAS6, GCG, HMGCR, HTR2C, ICAM1, IL1A, IL1B, JUN, KDR, NTRK1, P2RY1, PHB, PRKCA, PRKCZ, MAPK3, RAP1A, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SLAMF1, XCL2, VEGFA, VEGFB, FGF23, SEMA7A, TNFSF11, RIPK2, GPR55, RAPGEF2, ABCA7, PHB2 |
1204 | GO:0050896 | 0.00 | 3.20 | 81.51 | 148 | 251 | response to stimulus | SERPINA3, ACHE, ACO1, ACP2, ACTN1, ADD3, AK4, ALDH3A2, AMPD1, ANXA11, AOX1, ATP12A, ATP1B3, ATP4A, ATP5D, ATP5G3, BBS1, CA6, CACNA1B, CAPZB, SERPINH1, CD5L, ENTPD1, ENTPD6, CD48, CNGA2, CPOX, CRX, CSRP1, CST1, DBI, DSP, ELF3, EMX1, EMX2, ETFDH, GAD1, GAD2, GGCX, GJA4, GOT2, GPX2, GPX3, GPX7, GYS2, HBA1, HBA2, HBD, HBG1, HBG2, HPS1, HSPA4, ITIH4, AFF3, LAMP2, LIPA, LMAN1, LUM, NRL, OLR1, ORM2, SERPINA5, ATP8B1, PFKFB2, PFN1, PGGT1B, ABCB1, PPT1, PSG3, PTPN12, ABCD3, RNASE6, RNF2, RPN2, S100P, SCN2B, SCN8A, SCNN1A, SCNN1D, SCNN1G, SEPP1, SEPW1, SLC6A2, SLC6A11, SLC15A2, SLC22A1, SLC22A2, SLC22A5, SPRR3, SQLE, SRP14, SRP19, SRP68, STXBP1, TAF2, TNNT2, TOP1, TPSAB1, TUBA4A, USH2A, CLRN1, VCL, WEE1, ZNF148, VEZF1, SLC30A1, SLC30A2, MANF, MAFK, SLC7A5, SLC10A3, DYSF, KLRC4, BFSP2, ATRN, FOXN1, TPST1, AP3B1, PAGE1, PROZ, SYT7, CD163, KIF3B, SLC22A8, ABCG2, TP53I11, PRDX6, RNF7, WDR1, SLC23A2, SLC25A13, EIF1, ZNF443, KCNMB2, ABCC4, IRX5, HMG20B, CGRRF1, CGREF1, UGT2A1, ABHD2, KERA, KIF3A, SLC7A9, INMT, HPS5, SP140, SCN11A |
1205 | GO:0007157 | 0.01 | 3.20 | 9.60 | 16 | 23 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | CD6, CXADR, GRID2, ICAM1, ITGA4, ITGA5, ITGAL, CD200, REG3A, PTPRD, PVR, SELE, SELP, DCHS1, NRXN1, IL1RAPL1 |
1206 | GO:0045104 | 0.01 | 3.20 | 9.60 | 16 | 23 | intermediate filament cytoskeleton organization | DST, DSP, GFAP, AGFG1, KRT6A, KRT14, KRT16, KRT18, ATXN3, PRPH, RAF1, SHH, SOD1, VIM, BFSP2, INA |
1207 | GO:0048265 | 0.01 | 3.20 | 9.60 | 16 | 23 | response to pain | TSPO, CACNA1A, CACNA1B, CACNA1E, COMT, DBH, EDNRB, GJA4, NTRK1, P2RX3, PRKCG, RELN, SLC6A2, TAC1, UCN, TRPV1 |
1208 | GO:0071869 | 0.01 | 3.20 | 9.60 | 16 | 23 | response to catecholamine | ADCY6, APLP1, DNM2, GNAS, GNB1, KCNQ1, PARK2, PDE4B, PDE4D, PENK, PRKACA, RYR2, SLC9A1, SNCA, SRD5A1, STAR |
1209 | GO:1903201 | 0.01 | 3.20 | 9.60 | 16 | 23 | regulation of oxidative stress-induced cell death | ATF4, GPX1, HGF, HIF1A, HSPB1, INS, PARK2, PYCR1, SFPQ, SOD1, SOD2, TRPM2, VNN1, BAG5, HDAC6, TRAP1 |
1210 | GO:0051272 | 0.00 | 3.19 | 99.32 | 164 | 238 | positive regulation of cellular component movement | AAMP, ACP5, ACTN4, ACVR1, ACVR1B, ADAM10, AKT2, ALOX12, ANGPT1, ANXA3, APC, AQP1, ARHGAP5, BCL2, BMP4, BMPR2, C1QBP, SCARB1, CD74, CGA, CCR1, CMKLR1, COL1A1, CLDN7, DAB2, DIAPH1, HBEGF, S1PR1, LPAR1, EDN2, EDN3, EDNRA, EPHA1, ETS1, F2R, F2RL1, F3, F7, F10, FBLN1, FGF1, FGF7, FGR, FLT1, FLT4, GAS6, GATA3, GPLD1, GRB7, CXCL1, CXCL2, CXCL3, HAS2, HGF, HIF1A, ONECUT1, HSPB1, ICAM1, IFNG, IGF1, IGF1R, IL1B, ILK, INS, INSL3, ITGA2, ITGA3, ITGA4, ITGA5, ITGAV, ITGB1, JUN, KDR, KIT, EPCAM, SMAD3, KITLG, NTF3, NTRK3, DDR2, P2RY2, P2RY6, SERPINE1, PAWR, ENPP2, PF4, PF4V1, PFN1, PRKCA, PRKCE, PRKD1, PROX1, RELN, PTAFR, PTGER4, PTPRZ1, RAC1, RAC2, RDX, RPS19, RREB1, SERPINB3, CCL20, CCL21, CCL24, CXCL6, CXCL5, XCL1, CX3CL1, SDCBP, SELE, SELP, SEMA3F, SLC8A1, SNAI2, SNAI1, SOX9, SPARC, STAT5B, TAC1, TRIP6, TWIST1, VEGFA, VEGFB, VEGFC, VIL1, VTN, WNT11, ZP3, PTP4A1, SEMA3B, MADCAM1, SEMA7A, IKBKAP, NUMB, TNFSF14, ADAM9, RAB11A, TNFRSF18, NRP2, ARHGEF7, TNFSF18, ITGB1BP1, CHST3, ONECUT2, BAG4, CXCL14, BCAR1, RAPGEF2, SEMA3E, HDAC4, HDAC6, PDCD6, SEMA3A, ATP8A1, RAPGEF3, CREB3, SEMA6C, SEMA6B, SEMA4F, SEMA4B, CXCL13, PDPN, CORO1A |
1211 | GO:0010043 | 0.00 | 3.19 | 15.02 | 25 | 36 | response to zinc ion | ACP5, ALAD, ALDOB, ARG1, ASS1, ATP7B, BGLAP, TSPO, CA2, CPS1, GLRA1, GLRA2, HMBS, KCNK3, KHK, KRT14, LTA4H, OTC, P2RX7, PLN, S100A8, ABCC8, SLC30A1, SLC30A2, GGH |
1212 | GO:0033143 | 0.00 | 3.19 | 15.02 | 25 | 36 | regulation of intracellular steroid hormone receptor signaling pathway | NR0B1, ARNTL, BRCA1, CRY1, CRY2, DAB2, DDX5, EP300, GHRHR, PRMT2, IGF1, ISL1, CNOT2, PER1, PHB, PPP5C, RNF6, SKP2, SMARCA4, BUD31, RQCD1, CLOCK, HDAC6, CARM1, PHB2 |
1213 | GO:0097285 | 0.00 | 3.18 | 18.52 | 31 | 45 | cell-type specific apoptotic process | ABL2, ARF6, BMPR2, KRIT1, CD40, COL4A3, DNMT3A, E2F2, EIF2S1, FAP, FGA, FGG, ICAM1, IL13, KDR, KRT18, SERPINE1, PAX2, SERPINB13, RYR2, SORT1, SFRP4, SHH, SIX3, SOX9, TNFAIP3, PAX8, SCG2, AKR1C3, RAMP2, CAPN10 |
1214 | GO:0071383 | 0.00 | 3.18 | 22.78 | 38 | 55 | cellular response to steroid hormone stimulus | ACVR1, AGTR2, AHR, ANXA1, AQP1, ARG1, ASS1, ATP1A2, ATP2B1, KLF9, CASP9, DNMT3B, ELK1, FECH, FLT3, H2AFZ, HMBS, HMGCS2, IL10, ITGA2, NTS, PAWR, SERPINF1, SERPINB9, REST, SRD5A1, SSTR2, SSTR3, STAR, STC1, UBE2L3, AKR1C3, URI1, TRIM24, AIFM1, RAMP3, RUVBL2, CBX3 |
1215 | GO:0071241 | 0.04 | 3.18 | 5.39 | 9 | 13 | cellular response to inorganic substance | ATRX, BAD, DNM2, GUCY1B3, MAPK8, RAD51, TRAF2, TNFSF4, AIFM1 |
1216 | GO:0009891 | 0.00 | 3.18 | 27.15 | 46 | 68 | positive regulation of biosynthetic process | ABCA1, ADCY7, ADORA2A, ANXA1, APOA1, APOA4, APOC2, ASIP, AVP, AVPR2, CALCR, CALM3, SCARB1, CDH3, EDNRA, FSHR, GHRH, GHRHR, GLP1R, GNAL, GNAS, GPLD1, GUCA1A, GUCA1B, GUCA2A, GUCA2B, HTR2C, INSL3, NTRK2, P2RY11, PRKCA, PTHLH, RCVRN, SMPD2, TYRP1, VIP, VIPR2, WFS1, NSMAF, RGN, GUCA1C, CALCRL, RAMP2, CAP2, CAP1, ARPP19 |
1217 | GO:0070509 | 0.04 | 3.18 | 5.40 | 9 | 13 | calcium ion import | ATP2A1, CAV3, CDK5, GCG, SLC8A3, STC1, TRPC4, UCN, ZP3 |
1218 | GO:0033238 | 0.04 | 3.17 | 5.40 | 9 | 13 | regulation of cellular amine metabolic process | ABAT, SCARB1, CHRNB2, ACSL3, HPRT1, PARK2, PDE1B, SNCA, TACR3 |
1219 | GO:0034767 | 0.04 | 3.17 | 5.40 | 9 | 13 | positive regulation of ion transmembrane transport | CFTR, GCG, P2RX7, RELN, PTAFR, SLC34A1, STC1, UCN, ZP3 |
1220 | GO:0006333 | 0.04 | 3.16 | 5.41 | 9 | 13 | chromatin assembly or disassembly | CHD3, SMARCA4, SMARCC1, SMARCC2, SMARCD3, SMARCE1, TAL1, BAZ1B, SUPT16H |
1221 | GO:0071887 | 0.00 | 3.16 | 10.83 | 18 | 26 | leukocyte apoptotic process | ANXA1, BAX, BTK, CASP8, CD3G, CDKN2A, CLC, DFFA, IFNG, IL2RA, IL10, P2RX7, SIGLEC1, RIPK1, RAPGEF2, BCL2L11, SIVA1, TRAF3IP2 |
1222 | GO:0044273 | 0.04 | 3.16 | 5.41 | 9 | 13 | sulfur compound catabolic process | AGXT, CBS, CDO1, SLC25A10, CTH, GPC1, SUOX, TST, ACOT7 |
1223 | GO:0046634 | 0.00 | 3.16 | 16.28 | 27 | 39 | regulation of alpha-beta T cell activation | ADA, ANXA1, CBLB, CD28, CD80, CD86, CD55, GATA3, HLX, IFNG, IHH, IL18, IRF1, ITPKB, PRKCQ, PRKCZ, RARA, XCL1, SHH, SYK, TNFSF4, AP3B1, RIPK2, AP3D1, TNFSF18, EBI3, IKZF1 |
1224 | GO:0007179 | 0.00 | 3.16 | 22.90 | 38 | 55 | transforming growth factor beta receptor signaling pathway | ACVR1, ACVRL1, AMHR2, BMPR1A, CAV3, CBL, CCNC, CCNT1, CCNT2, CDK8, CDK9, COL3A1, E2F4, E2F5, FNTA, FUT8, GDF9, HPGD, ITGA3, ITGB5, JUN, JUNB, LTBP2, SMAD1, SERPINE1, PRKCZ, RBL1, SOX11, SP1, KLF10, UBE2D1, USP9X, USP9Y, LTBP4, ADAM9, NREP, GDF15, FERMT2 |
1225 | GO:0010631 | 0.00 | 3.15 | 12.02 | 20 | 29 | epithelial cell migration | APOA1, DPP4, EFNB2, EGR3, FAP, GPX1, NR4A1, ITGB1, KIT, KRT2, KRT16, PRKX, RAB13, S100A2, S100P, SRF, SCG2, TNFSF12, ZEB2, GIPC1 |
1226 | GO:0032330 | 0.04 | 3.15 | 5.42 | 9 | 13 | regulation of chondrocyte differentiation | BMP4, CTGF, EFEMP1, PTHLH, RARB, SNAI2, TRPS1, SIX2, ADAMTS7 |
1227 | GO:0005978 | 0.00 | 3.15 | 10.85 | 18 | 26 | glycogen biosynthetic process | AKT2, GYS2, IGF1, IGF2, INS, ENPP1, PGM1, PHKG1, PPP1CA, PPP1R3C, RPS27A, UBB, UGP2, EPM2A, DYRK2, NR1D1, EPM2AIP1, SORBS1 |
1228 | GO:0006369 | 0.00 | 3.15 | 10.85 | 18 | 26 | termination of RNA polymerase II transcription | CSTF3, MAZ, SRSF1, SRSF2, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SNRPE, SNRPF, U2AF1, TTF2, SRSF9, DHX38, ALYREF, PAPOLA, RNPS1 |
1229 | GO:0045840 | 0.00 | 3.15 | 10.85 | 18 | 26 | positive regulation of mitotic nuclear division | BIRC5, CD28, EDN3, EREG, FGF8, IGF1, IGF1R, IGF2, IL1A, IL1B, INS, RB1, AURKA, CUL3, BECN1, DLGAP5, UBE2C, PHB2 |
1230 | GO:0051496 | 0.00 | 3.15 | 10.85 | 18 | 26 | positive regulation of stress fiber assembly | APOA1, CTGF, LPAR1, EPHA1, LIMK1, SMAD3, PFN2, PRKCQ, RAC1, S100A10, SDC4, TAC1, WNT11, ARHGEF5, ITGB1BP1, BAG4, SORBS3, RAPGEF3 |
1231 | GO:2000273 | 0.00 | 3.15 | 10.85 | 18 | 26 | positive regulation of receptor activity | ADORA1, ADRA2C, ANXA2, CALM3, CDK5, CFTR, EREG, GSTM2, IGF2, PRKCE, RELN, BUD31, HAP1, BAZ1B, GSTO1, AKAP6, SRA1, TRDN |
1232 | GO:0070231 | 0.04 | 3.15 | 5.42 | 9 | 13 | T cell apoptotic process | CLC, TSC22D3, IL2RA, IDO1, PRKCQ, SIGLEC1, RIPK1, BCL10, SIVA1 |
1233 | GO:0061028 | 0.04 | 3.15 | 5.42 | 9 | 13 | establishment of endothelial barrier | F2RL1, RAPGEF1, ICAM1, PDE4D, RAP1A, RDX, EZR, RAPGEF2, RAPGEF3 |
1234 | GO:0001101 | 0.02 | 3.15 | 6.59 | 11 | 16 | response to acid chemical | CD9, AKR1C4, ATF2, HIF1A, HLCS, NTRK1, OTC, SHMT1, SIPA1, SCGB1A1, SLC14A2 |
1235 | GO:0007413 | 0.04 | 3.15 | 5.43 | 9 | 13 | axonal fasciculation | CNR1, EPHA3, EPHA4, EPHB2, EPHB3, NRCAM, PTPRZ1, CNTN2, SEMA3A |
1236 | GO:0009954 | 0.04 | 3.15 | 5.43 | 9 | 13 | proximal/distal pattern formation | APC, EN1, HOXC10, HOXC11, HOXD11, PBX1, SIX3, TP63, ALDH1A2 |
1237 | GO:0010470 | 0.04 | 3.15 | 5.43 | 9 | 13 | regulation of gastrulation | APOA1, BMPR1A, COL5A1, COL5A2, FOXA2, IL1RN, OTX2, FZD7, KLF4 |
1238 | GO:0030511 | 0.04 | 3.15 | 5.43 | 9 | 13 | positive regulation of transforming growth factor beta receptor signaling pathway | DAB2, ING2, MEN1, CITED1, SDCBP, STK11, ITGA8, CITED2, GIPC1 |
1239 | GO:0030866 | 0.04 | 3.15 | 5.43 | 9 | 13 | cortical actin cytoskeleton organization | ARF6, CDK5, DLG1, EPB41, EPB41L2, LLGL2, RAB13, VIL1, EZR |
1240 | GO:0032201 | 0.04 | 3.15 | 5.43 | 9 | 13 | telomere maintenance via semi-conservative replication | FEN1, PRIM1, PRIM2, RFC1, RFC2, RFC3, RFC4, RFC5, RPA3 |
1241 | GO:0032401 | 0.04 | 3.15 | 5.43 | 9 | 13 | establishment of melanosome localization | SHROOM2, BBS2, BBS4, CDH3, RAB1A, RAB27A, RAB27B, RAB11A, RAB11B |
1242 | GO:0032732 | 0.04 | 3.15 | 5.43 | 9 | 13 | positive regulation of interleukin-1 production | CASP5, HSPB1, IFI16, IFNG, ISL1, SMAD3, P2RX7, CCL20, TRIM16 |
1243 | GO:0035774 | 0.04 | 3.15 | 5.43 | 9 | 13 | positive regulation of insulin secretion involved in cellular response to glucose stimulus | BAD, CFTR, GCG, GPLD1, GPR27, HIF1A, OXCT1, VSNL1, C2CD2L |
1244 | GO:0042346 | 0.04 | 3.15 | 5.43 | 9 | 13 | positive regulation of NF-kappaB import into nucleus | EDA, IL1B, IL18, PRKCQ, TRIP6, TNFSF14, IL18R1, RBCK1, EDAR |
1245 | GO:0042481 | 0.04 | 3.15 | 5.43 | 9 | 13 | regulation of odontogenesis | APC, BMP4, RUNX2, EDNRA, FGF8, TNFRSF11B, PAX9, SHH, IFT88 |
1246 | GO:0042501 | 0.04 | 3.15 | 5.43 | 9 | 13 | serine phosphorylation of STAT protein | CDK5, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IL24 |
1247 | GO:0042749 | 0.04 | 3.15 | 5.43 | 9 | 13 | regulation of circadian sleep/wake cycle | ADA, ADORA1, ALB, CHRNB2, GHRH, GHRHR, KCNA2, PTGER4, PER3 |
1248 | GO:0043574 | 0.04 | 3.15 | 5.43 | 9 | 13 | peroxisomal transport | ABCD1, PEX1, PEX6, PEX10, PEX12, PEX14, PEX19, PEX5, PEX16 |
1249 | GO:0045956 | 0.04 | 3.15 | 5.43 | 9 | 13 | positive regulation of calcium ion-dependent exocytosis | ARF1, CDK5, GLRA1, STXBP1, SYT1, ZP3, CDK5R2, SYT7, UNC13B |
1250 | GO:0045992 | 0.04 | 3.15 | 5.43 | 9 | 13 | negative regulation of embryonic development | BMP4, COL5A1, COL5A2, GATA3, PRKACB, SNAI1, TULP3, FZD3, FZD7 |
1251 | GO:0046487 | 0.04 | 3.15 | 5.43 | 9 | 13 | glyoxylate metabolic process | AGXT, AMT, BCKDHA, DAO, DLD, IDH1, OGDH, PDHX, GRHPR |
1252 | GO:0060397 | 0.04 | 3.15 | 5.43 | 9 | 13 | JAK-STAT cascade involved in growth hormone signaling pathway | CISH, CSH1, GH2, MAPK3, PTPN1, PTPN6, STAT3, STAT5B, SOCS3 |
1253 | GO:0071354 | 0.04 | 3.15 | 5.43 | 9 | 13 | cellular response to interleukin-6 | ENTPD2, FGA, GFI1, PHB, PTGIS, SELPLG, STAT3, FGF23, ST3GAL6 |
1254 | GO:0090313 | 0.04 | 3.15 | 5.43 | 9 | 13 | regulation of protein targeting to membrane | AKT2, CDK5, STOM, ERBB2, GDI1, KCNE1, OGT, ITGB1BP1, C2CD5 |
1255 | GO:1900087 | 0.04 | 3.15 | 5.43 | 9 | 13 | positive regulation of G1/S transition of mitotic cell cycle | ANXA1, CDC6, DDX3X, KCNA5, RDX, UBE2E2, CDC45, CUL4B, CUL4A |
1256 | GO:1902170 | 0.04 | 3.15 | 5.43 | 9 | 13 | cellular response to reactive nitrogen species | AQP1, DNM2, DPEP1, GUCY1B3, HIF1A, MAP3K5, MAPK8, TRAF2, AIFM1 |
1257 | GO:1903170 | 0.04 | 3.15 | 5.43 | 9 | 13 | negative regulation of calcium ion transmembrane transport | ATP1A2, CALM3, CASQ2, GSTM2, NTSR1, PLN, SLN, GSTO1, TRDN |
1258 | GO:1903037 | 0.02 | 3.14 | 6.61 | 11 | 16 | regulation of leukocyte cell-cell adhesion | CAMK4, CD2, CLC, LMO1, RAC2, SOD1, SOS1, SOS2, FOXN1, SOX13, SPINK5 |
1259 | GO:1903317 | 0.00 | 3.13 | 17.53 | 29 | 42 | regulation of protein maturation | A2M, BIRC3, XIAP, BIRC5, C1QBP, SERPING1, C3, C5, C8B, CD59, CR1, CD55, F12, GAS1, HPN, KLKB1, CD46, SERPINE1, CFP, PHB, PRKACB, PROS1, RFX4, RPS6KA2, CNTN2, CLEC3B, VTN, IFT88, TMEM59 |
1260 | GO:0006874 | 0.00 | 3.13 | 78.46 | 129 | 188 | cellular calcium ion homeostasis | ABL2, ADCYAP1R1, ADRA1B, ANXA6, ATP1A2, ATP2A1, ATP2B1, ATP2B2, ATP7B, AVP, AVPR1B, BAX, BCL2, BDKRB2, BMP4, CACNA1A, CACNA1F, CACNB4, CALCR, CALM3, CASQ2, CAV3, CD4, CD36, CD38, CD40, CD52, CCR1, CCR3, CCR5, CCR8, CYBA, CD55, DIAPH1, S1PR1, LPAR1, S1PR3, EDN2, EDN3, EDNRA, EDNRB, ESR1, F2R, F2RL1, GALR1, GLP1R, GNA15, GNAT2, GNB1, CCR10, XCR1, GRINA, GRM1, GSTM2, GTF2I, HEXB, HRC, HTR2C, IL1B, IL13, ITGB1, ITPR1, ITPR2, ITPR3, KCNA5, KCNK3, KISS1, KNG1, NTSR1, OXT, P2RX3, P2RX4, P2RX7, P2RY1, P2RY2, P2RY4, PDE4D, PDPK1, PIK3CB, PIK3CG, PLN, PRKACA, PRKCA, PRKCB, PRKCE, PRKD1, PTH1R, PTPN6, PYGM, RAP1GDS1, RYR1, RYR2, RYR3, CCL21, XCL1, SLC8A1, SLC8A3, SNCA, STC1, TAC1, TNNI3, TPT1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, VDR, TRPV1, WFS1, XK, SLC30A1, CSRP3, S1PR4, INPP4B, HAP1, RGN, SLC24A1, VAPB, GSTO1, AKAP6, ATG5, TRDN, CIB2, CHERP, CXCL13, SCGN, CCR9, CORO1A |
1261 | GO:0008219 | 0.02 | 3.12 | 7.04 | 12 | 18 | cell death | PARP4, BRINP1, EIF4G2, EMP1, EMP2, EMP3, MEOX2, OLR1, KLK6, VAPA, SNCAIP, DPYSL4 |
1262 | GO:0007566 | 0.00 | 3.11 | 12.10 | 20 | 29 | embryo implantation | ACVR1B, ARHGDIB, BSG, C1QBP, EMP2, FBLN1, GRN, IL1B, IL11RA, ITGB4, PCSK5, PTGIS, RPL29, RXRA, SOD1, STC1, TRO, SCGB1A1, RECK, TRIM28 |
1263 | GO:0023051 | 0.00 | 3.11 | 31.65 | 54 | 82 | regulation of signaling | ACHE, ARF1, BCHE, CA2, CA7, CAMLG, CDC20, CHRNB2, CHRNB4, CNR2, DBI, DBN1, EGR2, EIF4EBP2, GFAP, GLRA1, GPM6B, GRIA1, GRIK3, HRH1, HRH2, ITGA2, KCNJ10, RAB8A, OXT, PFN2, SEPT5, PTN, RAB3A, RAB3B, RARA, SLC6A4, SLC18A1, SRF, STAR, STAU1, SYN1, SYT1, NR2E1, TNR, SLC30A1, LRP8, SYN3, RAB11A, SYNJ1, RAB11B, PICK1, RIN1, SNCAIP, RIMS3, BAIAP2, CSPG5, CPLX2, BVES |
1264 | GO:1901342 | 0.00 | 3.10 | 34.56 | 57 | 83 | regulation of vasculature development | ACVRL1, ALOX12, ANXA3, AQP1, BRCA1, BTG1, C3, C5, CHI3L1, CCR3, CTH, ECM1, EFNA1, EPHA2, EMP2, EPHA1, ERBB2, ETS1, F3, FGF1, FLT1, GATA4, GATA6, HGF, HIF1A, HSPB1, IL1A, IL1B, ISL1, ITGA5, KDR, KRT1, NTRK1, ENPP2, PGF, PRKCA, PRKCB, PRKD1, PTGIS, RAP1A, RRAS, CCL24, CX3CL1, SP100, NR2E1, TNFAIP3, TWIST1, VEGFA, VEGFB, VEGFC, SERPINB7, TNFSF12, RAPGEF2, PDCD6, RAMP2, RAPGEF3, CXCL13 |
1265 | GO:0031346 | 0.00 | 3.10 | 14.49 | 24 | 35 | positive regulation of cell projection organization | AQP1, BBS4, DNM2, EFEMP1, KAT2A, GPM6A, ITGA2, P2RX7, ENPP2, PFN1, PRKCQ, RAC1, RAC2, RALA, RREB1, CLRN1, VIL1, WNT1, ARHGEF7, HAP1, HDAC4, ARPC2, WASF2, SEPT9 |
1266 | GO:1903035 | 0.00 | 3.10 | 13.31 | 22 | 32 | negative regulation of response to wounding | ABAT, ALOX12, ANXA2, ANXA5, APOH, SERPING1, EPHA4, F12, FAP, FGA, FGG, GP1BA, HMGCR, HRG, KLKB1, KNG1, SERPINE1, PRKG1, PROS1, TNR, USF1, VTN |
1267 | GO:0061351 | 0.00 | 3.10 | 13.32 | 22 | 32 | neural precursor cell proliferation | RERE, DAGLA, DBN1, EML1, EMX2, EPHB1, FABP7, FGF8, GRN, HHEX, KCNA1, PCM1, RRM1, SOX5, TACC1, IFT88, FZD9, NUMB, NUMBL, ZEB2, TACC3, TACC2 |
1268 | GO:1900182 | 0.03 | 3.10 | 6.65 | 11 | 16 | positive regulation of protein localization to nucleus | CDKN2A, FYN, INS, STK11, CCT3, OGT, EIF2AK3, CCT7, CCT4, CCT2, CCT8 |
1269 | GO:0044774 | 0.00 | 3.10 | 26.71 | 44 | 64 | mitotic DNA integrity checkpoint | ATM, CCND1, CDKN1A, ATF2, FOXO4, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SETMAR, SOX4, TOP2A, TP73, UBB, XPC, TP63, CRADD, PSMF1, PSMD6, PSME3, CHEK2 |
1270 | GO:0046777 | 0.00 | 3.09 | 37.01 | 61 | 89 | protein autophosphorylation | ACVR1B, ALK, ATM, ATR, CAMK4, CAMK2A, CAMK2G, CDK5, CLK3, CSNK1G2, DCX, DYRK1A, EIF2S1, EPHA1, EPHA4, EPHA7, EPHA8, EPHB1, EPHB3, ERBB2, ERN1, FGFR3, FGFR4, FLT1, FLT3, FLT4, INSRR, IRAK1, JUN, KIT, MAP3K11, NTRK1, NTRK2, NTRK3, DDR2, ENPP1, PDPK1, PIM1, PRKCA, PRKCG, PRKD1, EIF2AK2, PRKX, AURKA, CDKL5, STK10, STK11, TYRO3, VRK1, MAPKAPK5, STK16, RIPK1, TRIM24, AURKB, STK17B, EIF2AK3, SLK, TRIM28, STK25, PIM2, CHEK2 |
1271 | GO:0008306 | 0.03 | 3.09 | 6.66 | 11 | 16 | associative learning | ADCY3, ADRB2, PPT1, RELN, SNAP25, SRF, TAC1, TNR, UCN, RIN1, TBR1 |
1272 | GO:0030038 | 0.00 | 3.09 | 20.03 | 33 | 48 | contractile actin filament bundle assembly | APOA1, ARHGAP6, BBS4, CTGF, S1PR1, LPAR1, EPHA1, ITGB5, LIMK1, TACSTD2, SMAD3, PFN1, PFN2, PRKCQ, PTGER4, RAC1, S100A10, SDC4, SLC9A1, SRF, TAC1, TSC1, WNT11, ALMS1, ARHGEF5, CUL3, ITGB1BP1, BAG4, WASF2, SORBS3, RAPGEF3, SORBS1, SYNPO |
1273 | GO:0008206 | 0.03 | 3.09 | 6.66 | 11 | 16 | bile acid metabolic process | ACAA1, ALB, FABP6, ATP8B1, RXRA, SLC10A1, SLC10A2, SLCO1A2, SULT2A1, ABCC3, SLCO1B1 |
1274 | GO:0002260 | 0.03 | 3.09 | 6.67 | 11 | 16 | lymphocyte homeostasis | ADA, TNFRSF17, CD74, HIF1A, SOS1, SOS2, SPTA1, TNFAIP3, IKBKG, BCL10, TNFSF13B |
1275 | GO:0006898 | 0.00 | 3.08 | 31.53 | 52 | 76 | receptor-mediated endocytosis | ADRB2, ALB, AMBP, APOA1, APOC2, ARF6, ASGR1, ASGR2, CAV2, CD5, CD5L, CD6, CD14, SCARB1, CETP, AP1S1, ACKR2, COL1A1, COL3A1, DMBT1, CTTN, EPS15, FTL, HBA1, HBA2, HP, HPX, HSP90AA1, IGF2R, LRP3, LRPAP1, OLR1, ENPP1, ENPP2, ENPP3, PI4KB, MAPK3, RAC1, SFTPD, SLC9A3, SORL1, SPARC, TMPRSS2, LRP8, CUBN, CLTCL1, PDLIM7, CD163, SNX17, PRG4, RABEPK, CAP1 |
1276 | GO:0030212 | 0.03 | 3.08 | 6.67 | 11 | 16 | hyaluronan metabolic process | CD44, HEXA, HEXB, HGF, ITIH1, ITIH2, ITIH3, ITIH4, MKI67, PIM1, SLC9A1 |
1277 | GO:0048538 | 0.00 | 3.08 | 13.35 | 22 | 32 | thymus development | APC, BCL2, CACNB4, EPHB3, FGF3, GATA3, HES1, JARID2, PAX1, PBX1, MAPK3, RAF1, RAG1, SHH, SIX1, SOD1, SRF, FOXN1, CCNB2, HAND2, BCL2L11, IKZF1 |
1278 | GO:0001709 | 0.03 | 3.08 | 6.67 | 11 | 16 | cell fate determination | BMP4, GATA3, GATA6, ISL1, NTF3, NTF4, PAX2, PROX1, PTCH1, PTCH2, KLF4 |
1279 | GO:0043277 | 0.03 | 3.08 | 6.67 | 11 | 16 | apoptotic cell clearance | AXL, CD36, SCARB1, FCN1, FCN2, GAS6, RAC1, RARA, TYRO3, FCN3, BECN1 |
1280 | GO:0006911 | 0.03 | 3.08 | 6.68 | 11 | 16 | phagocytosis, engulfment | ABCA1, CD36, CLCN3, F2RL1, FCER1G, ITGA2, MFGE8, RAC1, BECN1, ELMO1, ABCA7 |
1281 | GO:0008207 | 0.03 | 3.08 | 6.68 | 11 | 16 | C21-steroid hormone metabolic process | BMP6, CYP11B1, FDXR, REST, SCP2, SRD5A1, STAR, STAT5B, AKR1C3, DHRS9, DHRS2 |
1282 | GO:0010559 | 0.03 | 3.08 | 6.68 | 11 | 16 | regulation of glycoprotein biosynthetic process | BCL2, HBEGF, GOLGA2, IGF1, PAWR, CCL21, KAT2B, TMEM59, ACOT8, ABCA7, ARFGEF1 |
1283 | GO:0017144 | 0.03 | 3.08 | 6.68 | 11 | 16 | drug metabolic process | BCHE, CYP1A2, CYP2A6, CYP3A4, CYP3A5, DPEP1, FMO3, GUK1, PCK1, CYP4F2, NR1I2 |
1284 | GO:0032026 | 0.03 | 3.08 | 6.68 | 11 | 16 | response to magnesium ion | CCND1, BMP6, C3, CD14, ENTPD6, KCNA1, TNFRSF11B, RYR3, SLC34A1, SNCA, FGF23 |
1285 | GO:0035066 | 0.03 | 3.08 | 6.68 | 11 | 16 | positive regulation of histone acetylation | BRCA1, KAT2A, IL1B, ISL1, MAPK3, SNAI2, KAT2B, RPS6KA4, RPS6KA5, RUVBL2, ARID5A |
1286 | GO:0036230 | 0.03 | 3.08 | 6.68 | 11 | 16 | granulocyte activation | ANXA3, ACKR2, F2RL1, FCER1G, PTAFR, STXBP2, STXBP3, SYK, TYROBP, STX11, PRG3 |
1287 | GO:0045214 | 0.03 | 3.08 | 6.68 | 11 | 16 | sarcomere organization | ACTG1, CASQ2, CAV3, CFL2, ITGB1, KRT19, PRKAR1A, PROX1, SRF, TNNT2, WDR1 |
1288 | GO:0050802 | 0.03 | 3.08 | 6.68 | 11 | 16 | circadian sleep/wake cycle, sleep | ADA, ADORA1, ALB, CHRNB2, GHRH, GHRHR, KCNA2, PTGER4, SRD5A1, STAR, PER3 |
1289 | GO:0072210 | 0.03 | 3.08 | 6.68 | 11 | 16 | metanephric nephron development | AGTR2, AQP1, BMP4, GDNF, HES1, CITED1, PAX2, SALL1, SOX9, PAX8, SIX2 |
1290 | GO:1900117 | 0.03 | 3.08 | 6.68 | 11 | 16 | regulation of execution phase of apoptosis | BAX, BCL2L1, BOK, CDKN2A, DFFA, FAP, GCG, PTGIS, RPS3, FZD3, AIFM1 |
1291 | GO:1901381 | 0.03 | 3.08 | 6.68 | 11 | 16 | positive regulation of potassium ion transmembrane transport | ATP1B3, DNM2, DPP6, EDN3, KCNE1, KCNJ2, KCNQ1, AKAP7, AKAP6, AKAP9, RAPGEF3 |
1292 | GO:0002429 | 0.00 | 3.07 | 77.62 | 127 | 186 | immune response-activating cell surface receptor signaling pathway | ACTB, ACTG1, ADA, BAX, BCL2, BLK, BTK, CACNA1F, CACNB4, CALM3, CASP8, CBLB, CD3D, CD3G, CD4, CD28, CD38, CD79B, CDC42, CHUK, CR1, CR2, CTLA4, ELF1, EP300, FCER1G, FCGR2A, FCN1, FGR, FYB, FYN, GATA3, GPLD1, GRB2, HCK, HLA-DQA1, HSP90AA1, HSP90AB1, ICAM2, IL1B, ITPR1, ITPR2, ITPR3, KCNN4, KRAS, LIMK1, NRAS, PAWR, PDE4B, PDE4D, PDPK1, PIK3CB, PPP3R1, PRKACA, PRKACB, PRKACG, PRKCB, PRKCE, PRKCQ, MAPK3, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN6, PTPRJ, RAC1, RAF1, RELB, RPS27A, SKP1, STK11, SYK, UBB, UBE2D1, UBE2D2, UBE2V1, VAV1, EZR, LAT2, CUL1, IKBKG, RIPK2, BCL10, UBA3, RPS6KA5, THEMIS2, PSMF1, BCAR1, ELMO1, PSMD6, ABI1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, WASF2, PSME3, VAV3, BAIAP2, ARPC1A, RBCK1, MALT1 |
1293 | GO:0048639 | 0.00 | 3.07 | 14.57 | 24 | 35 | positive regulation of developmental growth | ADRB2, C3, CCNB1, EFNA5, FGF8, GATA4, GATA6, HLX, IGF1, RBPJ, PARK2, PROX1, PTGER4, RAG2, SYT1, SYT4, WNT2, ZP3, RND2, CPNE6, AKAP6, RIMS2, IST1, AGR2 |
1294 | GO:0008543 | 0.00 | 3.07 | 78.88 | 129 | 189 | fibroblast growth factor receptor signaling pathway | ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADRBK1, ANGPT1, BAD, CALM3, CAMK4, CAMK2A, CAMK2G, CASP9, RUNX2, CBL, CD28, CD80, CD86, CDKN1A, CHUK, CSF2, CSF2RB, CTGF, HBEGF, DUSP5, DUSP7, DUSP9, ERBB2, EREG, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FYN, GATA3, GPC1, GRB2, GRIN2A, NRG1, NR4A1, IL2RA, IL2RB, IL2RG, ITPR1, ITPR2, ITPR3, KIT, KRAS, MARK3, KITLG, FOXO4, NRAS, OTX2, PEBP1, PDE1B, PDPK1, PIK3CB, PPP2CB, PPP2R1A, PPP5C, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCE, PRKCG, MAPK3, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPRA, RAF1, RASA2, RPS6KB2, RPS27A, SHC1, SOS1, SPTA1, SPTB, TSC2, UBB, VAV1, SHOC2, FGF23, CUL3, PEA15, IQGAP1, FIBP, PSMF1, RAPGEF2, CEP57, PSMD6, RBX1, FGFBP1, AKAP9, RASA4, PSME3, FRS3 |
1295 | GO:0022407 | 0.01 | 3.07 | 9.06 | 15 | 22 | regulation of cell-cell adhesion | EFNA5, CELSR2, EPHA7, EPHB3, FGA, FGG, FOXA2, ITGA6, SMAD7, RAP1GAP, CX3CL1, SOX2, FSTL3, CITED2, CXCL13 |
1296 | GO:0051098 | 0.02 | 3.07 | 7.87 | 13 | 19 | regulation of binding | ANGPT1, APLP2, ATR, BCL2, BCL3, CDC42, EPHA4, NRG1, SMAD3, PRKACA, SMARCD3, CCPG1, HDAC4 |
1297 | GO:0032868 | 0.01 | 3.07 | 10.25 | 17 | 25 | response to insulin | CAT, CRY1, EGR2, HADHA, IL10, INPPL1, KHK, CITED1, OTC, PCK1, PLN, PTPRN, SORT1, STXBP3, ABCC8, GGH, EPM2AIP1 |
1298 | GO:0051239 | 0.00 | 3.07 | 58.33 | 99 | 152 | regulation of multicellular organismal process | ANXA6, APOA4, ATP1B3, FXYD2, ATP2B1, ATP2B2, BDKRB2, CACNA1B, CACNA1E, CACNA1F, CACNA1S, CACNA2D1, CACNB4, CACNG1, CALM3, CAMK2G, CASQ2, CCK, CHRM1, CNN1, DSC2, DSP, EGR2, ELAVL1, ELF1, ACKR1, GAA, GAMT, GLP1R, GRIN2A, GRM1, GSTM2, HTR2C, ITPR1, ITPR2, ITPR3, JUP, KCNA1, KCNA5, KCND2, KCND3, KCNE1, KCNJ2, KCNJ11, KCNJ12, KCNJ14, KCNK3, LCAT, PPP1R12B, CNOT2, OVGP1, PER1, FXYD3, PRKACA, RYR1, RYR3, S100A1, SCN2B, SCN4B, SCN5A, SCN10A, SLC8A3, SLN, SNTA1, SP4, SREBF1, SSTR2, TNNC2, TNNC1, TNNI2, TNNI3, TNNT2, TRPC1, SUMO1, ZFP36, CSRP3, ATRN, IQGAP1, SGPL1, DHRS3, SLC9A3R1, KCNK6, LITAF, NUP155, TRIL, KCNE2, HCN4, ABCC9, AKAP9, KCNMB2, IRX5, CACNG2, TRIM38, IGF2BP3, CORIN, AHCYL1, BVES, AKAP13, SCN11A |
1299 | GO:0070663 | 0.00 | 3.07 | 47.58 | 78 | 114 | regulation of leukocyte proliferation | ADA, ADK, AHR, ANXA1, ATM, BCL2, PRDM1, BMP4, CBLB, CD4, CD6, CD28, CD80, CD86, CD38, CD40, CD59, CD74, CDKN1A, CDKN2A, CHRNB2, CLC, CTLA4, CD55, DHPS, DLG1, GPR183, ERBB2, HES1, IFNG, IGF1, IGF2, IGFBP2, IHH, IL1B, IL2RA, IL10, IL13, IL18, IDO1, IRF1, ITGAL, LMO1, CD46, KITLG, PAWR, PRKAR1A, PRKCQ, PTPN6, RAC2, XCL1, SFTPD, SHH, ST6GAL1, SOS1, SOS2, SOX11, SPN, SPTA1, STAT5B, SYK, TAC1, TNFAIP3, TNFSF4, TNFRSF4, SCGB1A1, ZP3, PDE5A, TNFSF9, RIPK2, TNFSF18, EBI3, VAV3, TNFSF13B, GLMN, HHLA2, CORO1A, VSIG4 |
1300 | GO:0048598 | 0.00 | 3.06 | 28.49 | 47 | 69 | embryonic morphogenesis | ACVR2A, ACVR2B, APOA1, BMPR2, COL5A1, COL5A2, COL12A1, DLD, DUSP1, DUSP4, DUSP5, ETS2, ETV2, EXT1, EXT2, EYA2, FLT1, GATA6, FOXA2, HSBP1, IL1RN, ITGA2, ITGA3, ITGA5, ITGA7, ITGAV, ITGB1, ITGB4, ITGB5, LAMA3, SMAD1, PRKAR1A, RNF2, SNAI1, TAL1, UGDH, VTN, ZBTB17, EOMES, FZD7, CUL3, CHRD, LATS1, KLF4, CER1, ARFRP1, MAB21L2 |
1301 | GO:0043627 | 0.00 | 3.06 | 18.16 | 30 | 44 | response to estrogen | ADRB2, APOA1, AQP1, STS, BGLAP, CA2, CTNNA1, CYP27B1, DTYMK, EP300, F7, GATA3, GATA4, GATA6, GHRHR, KRT19, LDHA, SMAD6, MFGE8, CITED1, TNFRSF11B, SERPINB9, PTPRN, STAR, TSHB, TRIM25, RGS9, TRIM24, CITED2, SLC34A2 |
1302 | GO:0044033 | 0.00 | 3.06 | 50.08 | 82 | 120 | multi-organism metabolic process | CCNH, CCNT1, CDK9, CHD1, EP300, ERCC3, FAU, GTF2F1, HPN, JUN, RPL10A, NUP88, NUP98, RANBP2, REST, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, SMARCA4, SP1, SP100, SSRP1, SUPT4H1, TARBP2, TOP2A, TSG101, UBB, USF1, USF2, NUP214, AAAS, RPL14, CTDP1, RPL23, ATG5, NUP155, NUP93, IFITM3, ATG7, NUP50, NUPL2, SUPT16H, RPL35 |
1303 | GO:0060548 | 0.00 | 3.05 | 170.78 | 277 | 412 | negative regulation of cell death | ABL2, ACVR1, ADA, ADAR, ADCYAP1R1, ADORA1, AKT2, ALB, ALOX12, SLC25A4, ANXA1, ANXA4, ANXA5, APC, BIRC3, XIAP, BIRC5, APOH, AQP1, ARF4, ASNS, ATOH1, AVP, BAG1, BARD1, BCL2A1, BCL3, BDKRB2, BLK, BMP4, BNIP2, BNIP3, BNIP3L, BRCA1, CASP8, CAT, CBL, KRIT1, CD38, CD44, CD59, CD74, CDKN1A, CDKN2D, CLU, COL2A1, COMP, CLDN7, CRYAB, CSNK2A1, CTGF, CTH, CTNNA1, CX3CR1, DAB2, DAD1, DDB1, DDX3X, DFFA, DHCR24, DPEP1, TSC22D3, DUSP1, EDNRA, EDNRB, EGR3, CTTN, ERCC5, EYA1, FCER1G, FGA, FGG, FLNA, FLT4, IFI6, GAS6, GATA3, GATA6, GCG, SFN, GPX1, GRINA, HCK, HCLS1, HGF, NRG1, HMGCR, HPN, HSPA9, HSPB1, ICAM1, IFIT3, IGF1R, IHH, IL1A, IL1B, IL2RB, IL10, IDO1, ING2, INS, INSL3, IRAK1, ITGA6, ITGA5, ITGAV, ITGB1, ITPKB, KDR, KIT, KRT18, LTF, EPCAM, MAD2L1, SMAD3, SMAD6, KITLG, MGMT, YBX1, NTRK3, NTSR1, OGG1, OPA1, PA2G4, PAFAH2, SERPINE1, PDE3A, PDK4, PDPK1, SERPINB9, SERPINB13, PIM1, PIK3CG, PRKAA1, PRKCA, PRKD1, PRKCQ, PRKCZ, MAPK8, EIF2AK2, DNAJC3, PROC, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN1, PYCR1, RAF1, RAG1, RARA, RARB, RPS3A, RPS6KA1, RPS6KA3, RPS27A, CCL21, CX3CL1, SRSF6, SGK1, SHH, SIAH2, ST6GAL1, STIL, SLC9A1, SNAI2, SNAI1, SON, SOX4, SOX9, SOX10, SOX11, STAT5B, AURKA, SUPV3L1, NR2E1, TMF1, TNFAIP3, TPT1, TWIST1, UBB, UNG, VDAC2, VEGFA, VIL1, VIP, WNT1, WNT11, YWHAZ, ZNF16, PAX8, SCG2, FZD3, OGT, CBX4, API5, MADD, TP63, BECN1, PEA15, TRADD, URI1, RIPK1, TNFSF14, TNFSF10, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, CFLAR, WISP3, WISP1, HDAC3, TSC22D1, VNN1, TAX1BP1, BCL10, TNFSF18, SOCS3, RGN, ARHGEF2, AURKB, KLF4, EIF2AK3, HAND2, ATG5, PSMF1, BAG5, BAG4, BAG3, RB1CC1, PSMD6, AREL1, NR1H4, BCL2L10, TRAP1, PSME3, DHRS2, RAMP2, CITED2, RAPGEF3, ACAA2, CREB3, ATG7, AGR2, RBCK1, IVNS1ABP, ZMYND11, PROKR1, MALT1, PRDX3, PIM2, PHB2 |
1304 | GO:0042127 | 0.00 | 3.04 | 32.79 | 55 | 83 | regulation of cell proliferation | ABL2, XIAP, FXYD2, BID, BLK, BMX, BRCA1, BTK, DBH, DHCR7, DNMT1, E2F4, FANCA, FGR, FYN, CXCL2, CXCL3, GRPR, GUCY2C, HHEX, INHA, JUNB, JUND, JUP, LAMA5, TNFRSF11B, SERPINE1, PF4, PF4V1, PTGS1, RPA3, SAT1, CXCL6, SGK1, SRMS, TAL1, TNFRSF1A, TNFRSF1B, TYK2, TNK1, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, ARHGEF2, NUAK1, SGK2, TNK2, PRG4, CREB3, CXCL13, TXNIP, RBBP9, JTB |
1305 | GO:0006757 | 0.00 | 3.04 | 15.86 | 26 | 38 | ATP generation from ADP | ALDOB, ALDOC, ARNT, BPGM, ENO2, GAPDH, GPD1, HIF1A, HK2, IGF1, INS, LDHA, OGDH, P2RX7, PFKFB2, PFKFB4, PGAM2, PGK1, PGK2, PGM1, PPP2R5D, PRKAA1, STAT3, OGT, HDAC4, ECD |
1306 | GO:0009887 | 0.00 | 3.04 | 35.10 | 58 | 86 | organ morphogenesis | AES, APLP1, BMP1, CDX2, CDX4, CRX, CTGF, DCN, E2F4, E2F5, EFNB2, ELN, EP300, EREG, ERG, FGD1, FGF6, FLI1, GAA, GAMT, GATA6, GJA5, HCCS, HOXD8, IDUA, IGF2, ITGA2, ITGAX, JUN, ABLIM1, NTF4, SIX6, P2RX7, RFNG, RYR1, SFTPB, SLC8A1, SLIT3, SMARCC1, SMARCD3, SOX3, SYK, TRPS1, VEGFC, WHSC1, CUL1, FOXN1, TNFSF11, ADAM15, ALDH1A2, SGPL1, BAZ1B, ONECUT2, IFT140, COL4A3BP, OLFM1, TBR1, TREH |
1307 | GO:0015909 | 0.02 | 3.04 | 7.92 | 13 | 19 | long-chain fatty acid transport | AKT2, ABCD1, ANXA1, BDKRB2, SLC25A20, CPT1B, CPT2, ACE, NTSR1, PRKAB2, ABCD3, SYK, SLC27A5 |
1308 | GO:0055088 | 0.00 | 3.03 | 25.04 | 41 | 60 | lipid homeostasis | ABCA1, ABCA2, ACADL, ACADM, ACADS, ACADSB, ACADVL, ACOX1, APOA1, APOA4, APOC2, ASGR2, CAV3, SCARB1, CETP, ETFA, FGFR4, G6PC, GIP, GOT1, HPN, INS, IVD, LCAT, PRKAA1, ACSM3, NR1H2, USF1, USF2, ACOX2, ACOX3, SOAT2, DGAT1, LIPG, NR1D1, ABCG1, NR1H4, NR1D2, COL4A3BP, SEC24A, EHD1 |
1309 | GO:0055082 | 0.00 | 3.03 | 27.88 | 46 | 68 | cellular chemical homeostasis | BAD, CACNA1E, EFNA5, SLC29A1, EPHA5, ERN1, GAS6, GATA4, GCG, GHRHR, GPLD1, GPR27, HK2, HMGCR, FOXA2, ICAM1, IGF1, IGF1R, IL1R1, KCNJ11, MEN1, OXCT1, PAX2, CDK16, SERPINF1, PTGER4, PTPRN, PTPRN2, RAF1, RANBP2, RAP1A, SLC6A12, SMARCA4, SOX4, SRF, STAR, VSNL1, OGT, RAB11B, HMGN3, NRXN1, NR1D1, CARTPT, C2CD2L, NR1H4, GJB6 |
1310 | GO:0005980 | 0.02 | 3.03 | 7.93 | 13 | 19 | glycogen catabolic process | ADRA1B, CALM3, CPS1, G6PC, GAA, INS, PGM1, PHKA2, PHKG1, PPP1CA, PYGL, PYGM, STBD1 |
1311 | GO:0015985 | 0.02 | 3.03 | 7.93 | 13 | 19 | energy coupled proton transport, down electrochemical gradient | ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, ATP5J2, ATP5H, ATP5L |
1312 | GO:0030501 | 0.02 | 3.03 | 7.93 | 13 | 19 | positive regulation of bone mineralization | ACVR1, ACVR2A, ACVR2B, ADRB2, BMP4, BMP6, BMPR1A, BMPR2, GPM6B, LTF, SMAD3, P2RX7, SLC8A1 |
1313 | GO:0032722 | 0.02 | 3.03 | 7.93 | 13 | 19 | positive regulation of chemokine production | ALOX15B, C5, CD74, DDX3X, FFAR3, HIF1A, IFNG, IL1B, P2RY2, EIF2AK2, TWIST1, RIPK2, IL1RL1 |
1314 | GO:0042246 | 0.02 | 3.03 | 7.93 | 13 | 19 | tissue regeneration | ANXA1, BCL9, CCNB1, GAP43, GPX1, IGF1, PRKCQ, KLK6, PTPN12, SOX2, FZD7, ADAM15, CFLAR |
1315 | GO:0055010 | 0.02 | 3.03 | 7.93 | 13 | 19 | ventricular cardiac muscle tissue morphogenesis | COL11A1, DSP, NRG1, RBPJ, ISL1, SMAD7, PROX1, RXRA, RYR2, TNNC1, TNNI3, TNNT2, HAND1 |
1316 | GO:0060487 | 0.02 | 3.03 | 7.93 | 13 | 19 | lung epithelial cell differentiation | EYA1, GATA6, FOXA2, IGF1, RBPJ, IL13, LTA4H, NUMA1, SOX9, AIMP2, NUMB, KLF2, AGR2 |
1317 | GO:0030198 | 0.00 | 3.03 | 48.84 | 80 | 118 | extracellular matrix organization | ABL2, ACTN1, APLP2, BCL3, BMP4, DST, CD36, CD151, COMP, VCAN, CTGF, ECM2, ELF3, FBLN1, EFEMP1, FGA, FGG, GFAP, B4GALT1, GPX1, HSPA8, HSP90AB1, TNC, ICAM1, ICAM2, ICAM4, ILK, ITGA6, ITGA1, ITGA2, ITGA3, ITGA4, ITGA5, ITGA7, ITGA9, ITGAD, ITGAE, ITGAL, ITGAM, ITGAV, ITGAX, ITGB1, ITGB4, ITGB5, KDR, LAMA4, LTBP1, LTBP2, MATN3, MFAP3, TNFRSF11B, SERPINE1, VIT, PPIB, PRKCA, SDC1, SDC2, SDC4, SNCA, SPARC, SPINT1, NR2E1, TNR, VTN, PXDN, MADCAM1, LTBP4, RECK, ITGA8, RIPK1, NRXN1, SDC3, ADAMTSL2, SPOCK2, CRTAP, PRDX4, SPINT2, SPINK5, EMILIN1, B4GALT7 |
1318 | GO:0043066 | 0.00 | 3.02 | 129.00 | 210 | 313 | negative regulation of apoptotic process | ABL2, ACVR1, ADAR, ADORA1, ALB, ALOX12, ANXA1, ANXA4, ANXA5, APC, ARF4, ASNS, ATOH1, BAD, BAG1, BARD1, BCL2A1, BCL3, BDKRB2, BLK, BNIP2, BNIP3, BNIP3L, BRCA1, CAT, CBL, KRIT1, CD38, CD59, CDKN1A, CLU, COL2A1, COMP, CLDN7, CSF2, CTH, CTNNA1, CX3CR1, DAB2, DAD1, DDB1, DFFA, DUSP1, EDNRA, EDNRB, EGR3, CTTN, ERCC5, EYA1, FGA, FGG, FLNA, FLT4, GATA3, GATA6, GCG, GRINA, HCK, NRG1, HMGCR, HPN, HSPA9, HSPB1, ICAM1, IFIT3, IGF1, IGF1R, IHH, IL1A, IL1B, IL2RB, IL10, IL13, ING2, INS, INSL3, IRAK1, ITGA6, ITGAV, KDR, KRT18, LTF, EPCAM, MAD2L1, SMAD3, SMAD6, YBX1, NTSR1, OGG1, OPA1, PA2G4, PAFAH2, SERPINE1, PDE3A, PDPK1, PF4, SERPINB13, PIM1, PIK3CG, PRKAA1, PRKCA, PRKCZ, MAPK8, EIF2AK2, DNAJC3, PROC, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN1, RARA, RARB, RPS3A, RPS27A, CX3CL1, SGK1, STIL, SLC9A1, SNAI1, SON, SOX10, STAT3, STAT5B, AURKA, SUPV3L1, NR2E1, TMF1, TNFAIP3, TPT1, TWIST1, UBB, UCN, UNG, VDAC2, VIP, WNT1, WNT11, YWHAZ, ZNF16, SCG2, FZD3, CBX4, API5, MADD, TP63, BECN1, PEA15, URI1, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10D, HDAC3, TSC22D1, VNN1, TAX1BP1, TNFSF18, SOCS3, RGN, ARHGEF2, EIF2AK3, HAND2, ATG5, PSMF1, BAG5, BAG4, BAG3, RB1CC1, PSMD6, AREL1, NR1H4, BCL2L10, TRAP1, PSME3, DHRS2, RAMP2, CITED2, RAPGEF3, ACAA2, CREB3, ATG7, IVNS1ABP, ZMYND11, PROKR1, MALT1, PIM2, PHB2 |
1319 | GO:0051291 | 0.00 | 3.02 | 18.31 | 30 | 44 | protein heterooligomerization | ACVRL1, BIRC3, CASP8, CHRNB2, CHRNB4, COL1A1, COL6A2, CLDN3, CTNNA1, GLRA1, GLRB, HBA1, HBA2, IDE, ILK, ITPR3, JUP, PPP5C, PRKAA1, PRKCZ, SEMG1, STXBP3, TNNT2, TRAF2, TSC1, OGT, TRADD, RIPK1, BCL10, SEPT9 |
1320 | GO:0034329 | 0.00 | 3.02 | 31.16 | 51 | 75 | cell junction assembly | ACTB, ACTG1, ACTN4, ANG, APC, ARL2, CD9, CDH1, CDH3, CDH6, CDH7, CDH8, CDH9, CDH10, CDH12, CDH15, CDH17, CLDN3, CTNNA1, CTNND1, ACE, DLG1, ECT2, FLNA, FLNC, GJA4, GJA5, GJB1, GJB2, RAPGEF1, ILK, ITGB1, LIM2, PRKACA, PRKCA, PRKCI, PVR, RAB13, RAP1A, RSU1, SNAI2, SNAI1, SRF, STRN, UGT8, WNT11, FZD5, CNTNAP1, CLDN12, ARHGEF6, RAPGEF2 |
1321 | GO:0007596 | 0.00 | 3.01 | 67.73 | 111 | 165 | blood coagulation | ADORA2A, ANGPT1, ANGPT2, ATP1B3, ATP2A1, ATP2B1, ATP2B2, BSG, C3, CAPZA1, CAPZB, CD2, ENTPD1, CD44, CD48, CD58, CD59, CD74, CDC42, CDK5, CENPE, CXADR, F2RL1, FGR, GATA3, GATA4, GATA6, GGCX, GRB7, GUCY1B3, H3F3B, HBD, HBG1, HBG2, SERPIND1, FOXA2, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, ITGA6, IRF1, IRF2, ITGA1, ITGA2, ITGA3, ITGA4, ITGA5, ITGAL, ITGAM, ITGAV, ITGAX, ITGB1, KIF5A, KLC1, KRAS, LMAN1, NRAS, OLR1, SERPINA5, PDE3A, PDE3B, PDE1B, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, RAB27A, RAD51B, SELE, SELL, SELPLG, SHH, SLC8A1, SLC8A3, SLC16A1, SPN, WEE1, LRP8, MAFK, SLC7A5, AKAP1, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, CYP4F2, AP3B1, PDE5A, CD84, PROZ, HIST1H3F, DOK2, PAPSS2, KIF3B, SH2B3, KCNMB2, HMG20B, PROCR, SH2B2, PDE10A, EHD1, KIF3A, SLC7A9, AKAP10, HPS5 |
1322 | GO:0034138 | 0.00 | 3.01 | 18.36 | 30 | 44 | toll-like receptor 3 signaling pathway | BIRC3, CASP8, CD14, CD86, CHUK, ATF2, DUSP4, DUSP7, ELK1, F2RL1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK3, MAPK8, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, TNFAIP3, UBB, UBE2D1, UBE2D2, CUL1, IKBKG, RIPK1, RIPK2, RPS6KA5 |
1323 | GO:0045766 | 0.00 | 3.01 | 28.80 | 47 | 69 | positive regulation of angiogenesis | ACVRL1, ALOX12, ANGPT2, ANXA3, AQP1, BRCA1, BTG1, C3, C5, CHI3L1, CCR3, CX3CR1, ECM1, EPHA1, ETS1, F3, FGF1, FLT1, GATA4, GATA6, HGF, HIF1A, HSPB1, IL1A, IL1B, ISL1, ITGA5, KDR, NTRK1, SERPINE1, PGF, PRKCA, PRKCB, PRKD1, PTGIS, RRAS, CCL24, CX3CL1, NR2E1, TWIST1, VEGFA, VEGFB, VEGFC, TNFSF12, PDCD6, RAMP2, RAPGEF3 |
1324 | GO:0050670 | 0.01 | 3.01 | 10.37 | 17 | 25 | regulation of lymphocyte proliferation | ADA, AHR, ATM, BCL2, PRDM1, CD38, CD40, CD74, CDKN1A, CHRNB2, CTLA4, GPR183, IL13, SOX11, TAC1, TNFRSF4, VAV3 |
1325 | GO:0035637 | 0.00 | 3.01 | 32.44 | 53 | 78 | multicellular organismal signaling | ATP1A2, ATP1B3, FXYD2, ATP2A1, ATP2B1, ATP2B2, CACNA1F, CACNA1S, CACNA2D1, CACNG1, CALM3, CASQ2, CXADR, DSC2, DSP, GJA5, HRC, ITPR1, ITPR2, ITPR3, JUP, KCNA5, KCND3, KCNE1, KCNJ2, KCNJ11, KCNJ12, KCNJ14, KCNK3, KCNQ1, PDE4D, FXYD3, PLN, PRKACA, RYR1, RYR2, RYR3, SCN2B, SCN4B, SLC8A1, SLC8A3, SLC9A1, TNNI3, TRPC1, KCNK6, NUP155, KCNE2, HCN4, ABCC9, AKAP9, TRDN, CORIN, AHCYL1 |
1326 | GO:2000026 | 0.00 | 3.00 | 60.39 | 100 | 151 | regulation of multicellular organismal development | ACVR1, ACVR2B, AHSG, APOA1, ARHGDIB, CCND1, BMP1, BRCA2, C1QBP, CBLB, CCNB1, CD40, CDX1, CDX2, CENPF, CLC, COL1A1, COL5A1, COL5A2, CTGF, CXADR, DDX5, DMBT1, TSC22D3, E4F1, S1PR1, S1PR3, EFNB2, ETV2, FOXD1, NR5A1, GDF9, GNAQ, GPC1, GPM6B, GPX1, HMGCR, IL1RN, IL10, IL13, IDO1, KCNK2, LAMA3, LAMA4, LAMA5, SMAD1, SMAD3, SMAD7, NRAS, DDR2, OMD, OTX2, P2RX7, ENPP1, SRGN, PRKAA1, MAPK8, PRKX, PROC, PTHLH, RFX3, RREB1, S100B, SERPINB3, SDCBP, SFRP5, SLC8A1, SNAI1, SRY, TNFRSF1A, NR2C2, TRPS1, COL14A1, UNG, WHSC1, WNT1, ZIC2, ZP3, FGF23, TNFSF13, HDAC3, PROM1, USP2, RGN, CTDP1, S1PR2, IL27RA, AKAP6, CLOCK, PHF14, HDAC4, ZEB2, RBM19, NR1D2, MAD2L2, DEAF1, DMRT2, USP19, STRAP, ADAMTS7 |
1327 | GO:0006734 | 0.01 | 3.00 | 9.18 | 15 | 22 | NADH metabolic process | ALDOB, ALDOC, ENO2, GAPDH, GPD1, HK2, LDHA, MDH1, MDH2, OGDH, PFKFB2, PFKFB4, PGAM2, PGK1, PPP2R5D |
1328 | GO:0009409 | 0.01 | 3.00 | 9.18 | 15 | 22 | response to cold | ADRB2, ATP2B1, CASP8, CDH8, CIRBP, GK, HSP90AA1, IMPDH1, P2RX3, PRKAA1, DNAJC3, RBM3, TRH, EIF2AK3, ZNF516 |
1329 | GO:0018149 | 0.01 | 3.00 | 9.18 | 15 | 22 | peptide cross-linking | ANXA1, COL3A1, DCN, DSP, EPB42, IVL, SPRR1B, SPRR2A, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3, SPOCK2, ABCA7 |
1330 | GO:0046173 | 0.01 | 3.00 | 9.18 | 15 | 22 | polyol biosynthetic process | ADCYAP1R1, CYP3A4, CYP27B1, GOT1, HRH1, IMPA1, IMPA2, NTSR1, P2RY1, PCK1, PTAFR, PTH1R, SCP2, SNCA, SPTLC1 |
1331 | GO:0048635 | 0.01 | 3.00 | 9.18 | 15 | 22 | negative regulation of muscle organ development | BMP4, CAV3, CXADR, TSC22D3, FGF3, FGF8, KCNK2, NRAS, S100B, TP73, TWIST1, HDAC3, USP2, CTDP1, USP19 |
1332 | GO:0060976 | 0.01 | 3.00 | 9.18 | 15 | 22 | coronary vasculature development | AP2B1, PRDM1, DNM2, GATA6, GPC3, LTBP1, SMAD6, PCSK5, PTK7, SRF, VEGFA, VEGFB, HAND2, SNX17, SEC24B |
1333 | GO:0071868 | 0.01 | 3.00 | 9.18 | 15 | 22 | cellular response to monoamine stimulus | ADCY6, APLP1, DNM2, GNAS, GNB1, KCNQ1, PARK2, PDE4B, PDE4D, PRKACA, RYR2, SLC9A1, SNCA, SRD5A1, STAR |
1334 | GO:1901028 | 0.01 | 3.00 | 9.18 | 15 | 22 | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | BAD, BAX, BCL2, BID, CASP8, SFN, PPP3R1, MAPK8, YWHAG, YWHAH, YWHAZ, DYNLL1, BCL2L11, ACAA2, SIVA1 |
1335 | GO:0006073 | 0.00 | 3.00 | 19.61 | 32 | 47 | cellular glucan metabolic process | ADRA1B, AKT2, CALM3, CPS1, G6PC, GAA, GCGR, GYS2, IGF1, IGF2, INS, KHK, ENPP1, PGM1, PHKA2, PHKG1, PPP1CA, PPP1R1A, PPP1R2, PPP1R3C, PYGL, PYGM, RPS27A, UBB, UGP2, EPM2A, DYRK2, MGAM, STBD1, NR1D1, EPM2AIP1, SORBS1 |
1336 | GO:0051099 | 0.01 | 2.99 | 10.41 | 17 | 25 | positive regulation of binding | ANXA2, CDK9, CEBPG, GATA3, KAT2A, HES1, IGF1, ISL1, PARK2, RARA, S100A10, TWIST1, EDF1, KAT2B, KLF4, HAND2, RAPGEF3 |
1337 | GO:1903038 | 0.00 | 2.98 | 20.87 | 34 | 50 | negative regulation of leukocyte cell-cell adhesion | ANXA1, ASS1, BMP4, CBLB, CD74, CDKN2A, CTLA4, CYLD, DLG1, DTX1, ERBB2, HLX, IFNA2, IHH, IL2RA, IL10, IDO1, IRF1, PAWR, PRKAR1A, PTPN6, CCL21, CCL25, XCL1, SFTPD, SHH, SPN, TNFSF4, SCGB1A1, PDE5A, TNFSF18, SOCS6, GLMN, VSIG4 |
1338 | GO:0006936 | 0.00 | 2.98 | 33.04 | 54 | 80 | muscle contraction | ACTA2, ANXA1, ANXA2, ARG2, BBS2, BDKRB2, CACNA1S, CACNG1, CHRNB2, CHUK, LTB4R, CRYAB, DLG1, DTNA, EDN3, EDNRA, EDNRB, EEF2, EMD, GAA, GAMT, GDNF, GLRA1, HSBP1, ITGA1, ITGB5, KCNA5, KCNE1, KCNJ12, KNG1, P2RX3, PGAM2, PIK3C2A, RYR1, SCN2B, SCN4B, SRSF1, SLC6A8, SNTA1, SNTB1, TAZ, VCL, VEGFB, VIPR1, TRPV1, CSRP3, DYSF, STBD1, NUP155, KCNE2, COL4A3BP, SORBS3, TRDN, SORBS1 |
1339 | GO:0090090 | 0.00 | 2.98 | 35.06 | 57 | 84 | negative regulation of canonical Wnt signaling pathway | AES, APC, CTNND1, CYLD, DAB2, RAPGEF1, IGFBP2, IGFBP6, ISL1, PARK2, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SFRP4, SFRP5, SHH, SIAH2, SNAI2, SOX2, SOX9, SOX10, UBB, WNT11, FZD6, CUL3, LATS1, PSMF1, PSMD6, RBX1, G3BP1, PSME3, APC2, MAD2L2 |
1340 | GO:0016444 | 0.01 | 2.98 | 10.43 | 17 | 25 | somatic cell DNA recombination | ATM, CD28, CD40, ERCC1, IFNG, IL10, RAG1, RAG2, TNFSF4, UNG, WHSC1, TNFSF13, RNF8, EXO1, IL27RA, VPRBP, BATF |
1341 | GO:1903707 | 0.00 | 2.97 | 11.65 | 19 | 28 | negative regulation of hemopoiesis | CDK6, GABPA, PRMT1, HES1, ITPKB, MEIS1, PF4, STAT5B, HIST1H4I, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, GAS2L1 |
1342 | GO:0007173 | 0.00 | 2.97 | 95.99 | 155 | 230 | epidermal growth factor receptor signaling pathway | ABL2, ADAM10, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADORA1, ADRA2C, ADRBK1, AP2A1, AP2B1, ANGPT1, APLP2, AREG, ARF4, BAD, CALM3, CAMK4, CAMK2A, CAMK2G, CAMLG, CASP9, CBL, CD28, CD80, CD86, CDC42, CDKN1A, CHUK, AP2M1, AP2S1, CLTA, CSF2, CSF2RB, HBEGF, DUSP5, DUSP7, DUSP9, EPS8, EPS15, ERBB2, EREG, ESR1, EFEMP1, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FYN, GRB2, GRB7, GRIN2A, NRG1, NR4A1, IL2RA, IL2RB, IL2RG, ITGA1, ITPR1, ITPR2, ITPR3, KIT, KRAS, MARK3, KITLG, FOXO4, NRAS, PEBP1, PDE6G, PDE6H, PDE1B, PDPK1, PIGR, PIK3C2A, PIK3CB, PPP5C, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCE, PRKCG, MAPK3, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPRA, PTPRJ, RAF1, RASA2, RPS6KB2, RPS27A, SHC1, SOS1, SOX9, SPTA1, SPTB, TSC2, UBB, VAV1, VIL1, RAB7A, STAM, FGF23, CUL3, PEA15, IQGAP1, ARHGEF7, HAP1, REPS2, RPS6KA5, PSMF1, BCAR1, RAPGEF2, RASSF2, PSMD6, RBX1, AKAP9, RASA4, PSME3, STAM2, AGR2, FRS3 |
1343 | GO:0048546 | 0.00 | 2.96 | 11.69 | 19 | 28 | digestive tract morphogenesis | ACVR2B, BCL2, BMP4, EPHB3, FGFR3, GATA4, HIF1A, HLX, IHH, SMAD3, SFRP5, SHH, SOX10, SOX11, TP73, WNT11, TP63, AGR2, SIX2 |
1344 | GO:1902110 | 0.00 | 2.96 | 11.69 | 19 | 28 | positive regulation of mitochondrial membrane permeability involved in apoptotic process | BAD, BAX, BCL2, BID, BNIP3, BNIP3L, CASP8, ATF2, EYA2, SFN, PPP3R1, MAPK8, YWHAG, YWHAH, YWHAZ, DYNLL1, BCL2L11, ACAA2, SIVA1 |
1345 | GO:0031397 | 0.00 | 2.95 | 42.57 | 69 | 102 | negative regulation of protein ubiquitination | APC, ATM, BUB1, BUB1B, TSPO, CCNB1, CDC20, CDC27, CDK5, CDKN2A, CENPF, CRY1, DUSP1, FYN, LIMK1, MAD2L1, SMAD7, PRKCE, PRKCG, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS3, RPS27A, SOX4, TNFAIP3, UBB, UBE2D1, USP4, WNT1, ZNF207, OGT, CDC23, CDC16, ZW10, BUB3, TRIP12, ATG5, PSMF1, BAG5, PSMD6, PSME3, ANAPC10, MAD2L2, UBE2C, GLMN |
1346 | GO:0009952 | 0.00 | 2.95 | 14.13 | 23 | 34 | anterior/posterior pattern specification | ACVR2A, ACVR2B, APC, BMPR2, CELSR2, EMX2, GATA4, GRSF1, HOXC10, HOXC11, HOXD3, HOXD4, HOXD11, OTX1, PBX1, PCSK5, SIX3, NR2F2, TULP3, WNT2, WNT2B, IFT88, ALDH1A2 |
1347 | GO:0045597 | 0.00 | 2.95 | 18.26 | 30 | 45 | positive regulation of cell differentiation | ARNTL, KLF5, CCNE1, CD36, CDX2, CLU, CMKLR1, CREBL2, CSF2, CTGF, EDN3, FGFR3, GATA4, GATA6, GFI1, GPC1, HTR2C, INS, JUNB, KDR, TACSTD2, PA2G4, RPS6KA1, RPS6KA3, SNAI2, SULT1E1, EOMES, SOCS3, RAMP2, CARM1 |
1348 | GO:2000242 | 0.00 | 2.94 | 12.94 | 21 | 31 | negative regulation of reproductive process | ADA, APC, ARHGDIB, BMP4, DUSP1, NR5A1, IGF1, OVGP1, OVOL1, SERPINF1, PRKACB, PRKAR1A, RAD1, RPS6KA2, SNAI1, STK11, ZP2, ZP3, TPST2, PRDX4, PTGDR2 |
1349 | GO:1903532 | 0.00 | 2.94 | 20.27 | 33 | 49 | positive regulation of secretion by cell | AP1G1, ATP6AP1, AVP, CCK, CDK5, FCER1A, FCER1G, GLRA1, NTSR1, SEPT5, PTAFR, RAB3A, RAB27A, RAB27B, SDC1, SDC4, SDCBP, SNCA, STXBP1, SYT1, TACR2, TSG101, ZP3, RAB7A, STAM, CDK5R2, SYT7, RAB9A, RAB3D, GAB2, PDCD6IP, UNC13B, SNF8 |
1350 | GO:0019882 | 0.00 | 2.94 | 35.75 | 58 | 86 | antigen processing and presentation | AZGP1, CD1B, CD8A, CD36, CYBA, ACE, FCGR1B, FCGRT, ICAM1, IFNG, ITGAV, ITGB5, ABCB1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RAB3B, RAB4A, RAB6A, RAB27A, RELB, RPS27A, CCL21, SLC11A1, UBB, KDM5D, AP3B1, AP3D1, RAB33A, PSMF1, PSMD6, PSME3, SEC61B, RAB32, RAB35 |
1351 | GO:0043524 | 0.00 | 2.94 | 29.63 | 48 | 71 | negative regulation of neuron apoptotic process | AARS, ANGPT1, AXL, BAX, BCL2, BCL2L1, CACNA1A, CNTF, F2R, FGF8, FYN, GABRB2, GDNF, HIF1A, HSP90AB1, ILK, ISL1, JUN, KRAS, CITED1, NTF3, NTF4, NTRK1, NTRK2, PARK2, PCP4, PPT1, PRKCG, PRKCI, SET, ITSN1, SIX1, SNCB, SNCA, SOD1, SOD2, STAR, STXBP1, PRDX2, TP73, TYRO3, VEGFB, WFS1, XRCC2, CRLF1, STAMBP, CHL1, CORO1A |
1352 | GO:1903076 | 0.00 | 2.93 | 14.19 | 23 | 34 | regulation of protein localization to plasma membrane | ARF6, BCL2L1, AP2M1, CLTC, DAB2, DLG1, EPHA2, ACSL3, IFNG, ITGA3, ITGB1, PDPK1, PRKCI, VIL1, EZR, NUMB, VAMP8, NRXN1, TMEM59, RAMP3, AGR2, SORBS1, RER1 |
1353 | GO:0010720 | 0.00 | 2.93 | 65.54 | 106 | 158 | positive regulation of cell development | ABL2, ADRA2C, BIN1, APBB1, ARF1, ATOH1, ATP6AP1, BAD, BAX, BCL2, BMP4, BMP6, TSPO, CNR1, CRX, CX3CR1, BRINP1, DNMT3B, DPYSL3, ECT2, LPAR1, EIF4G1, EPHA3, ETV5, FYN, GFAP, B4GALT1, RAPGEF1, GRN, ARHGAP35, HGF, HIF1A, FOXA2, HOXD3, HOXD11, HES1, IFNG, IL1B, ITGA3, ITGB1, KIT, NRCAM, NTF3, NTRK1, OPA1, P2RY2, PARK2, PCP4, PDE3A, SERPINF1, PRKCI, PRKD1, PROC, PROX1, PTK7, PTN, PTPRZ1, RAP1A, RARA, RARB, RFX3, RHEB, SALL1, CX3CL1, SHH, SMARCD3, SOX2, SOX10, SOX11, SPINT1, STAR, AURKA, SYT1, SYT4, TP73, VDR, VEGFC, WNT2, XRCC2, RNF112, FZD3, SF3A2, CAMK1, TNFSF11, NUMB, PDE5A, KAT2B, CPNE1, PHOX2B, HAP1, CBFA2T2, S1PR2, CPNE6, AKAP6, ADAMTS1, RAPGEF2, RIMS2, FIG4, OLIG2, TRIB1, KATNB1, HMG20B, SEMA3A, RGS14, AVIL, STMN2 |
1354 | GO:0009057 | 0.00 | 2.93 | 44.96 | 73 | 109 | macromolecule catabolic process | AMBP, BARD1, CAPN1, CBLB, CD44, CDC42, CDK5, TPP1, CLN5, VCAN, CSPG4, CTSD, CTSE, DCN, ACE, ENPEP, GPC4, GPC5, FLNA, FYN, GALNS, GPC3, GLB1, GPLD1, GRIN2A, HEXA, HEXB, NRG1, IDS, IDUA, IFNG, IL1B, IL10, LUM, SMAD3, OAZ1, OAZ2, ODC1, OMD, OGN, OVGP1, P2RX7, PGA5, PGC, PHB, PTPN1, PTPN3, SDC1, SDC2, SDC4, SGSH, SLC9A1, SORL1, SOX9, TNFRSF1B, TRAF2, UVRAG, VIP, BECN1, TNFSF12, ADAM9, TRIM24, PGLYRP1, SEC22B, SDC3, GPRASP1, GPC6, PRSS16, APC2, ATG7, CSPG5, KERA, LYPLA2 |
1355 | GO:0070486 | 0.00 | 2.93 | 101.41 | 163 | 243 | leukocyte aggregation | ABL2, ADA, ADK, ANXA1, APC, RHOH, BAD, BAX, BCL2, BCL3, BMP4, BMX, ZFP36L2, CAMK4, CASP8, RUNX2, CBLB, CCND3, CD2, CD3D, CD3G, CD4, CD5, CD6, CD7, CD8A, CD28, CD80, CD86, TNFSF8, CD44, CD59, CD74, CD151, CDC42, CDK6, CDKN2A, CLC, CTLA4, CXADR, CYLD, CD55, DHPS, DLG1, DPP4, DTX1, EFNB2, EGR3, ERBB2, F2RL1, FCER1G, FLOT2, FLT3, FYN, GATA3, GRB2, HAS2, HLA-DQA1, HLX, HES1, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF2, IGFBP2, IHH, IL1B, IL2RA, IL10, IL18, IDO1, INS, IRF1, ITGAD, ITGAL, ITPKB, KIT, LMO1, SMAD3, CD46, P2RX7, PAWR, PAX1, PDPK1, PIK3CG, PRKAR1A, PRKCQ, PRKCZ, PSMB10, PTGER4, PTPN6, RAB27A, RAC1, RAC2, RAG1, RAG2, RARA, RELB, RPL22, S100A8, S100A9, SATB1, CCL21, XCL1, SFTPD, SHH, SLC11A1, SOD1, SOS1, SOS2, SOX4, SP3, SPN, SPTA1, SRF, STAT5B, STK10, STK11, SYK, TRAF2, TSC1, TNFSF4, TNFRSF4, SCGB1A1, VAV1, WNT1, ZP3, FZD5, EOMES, FZD7, FZD8, FOXN1, AP3B1, TNFSF11, PDE5A, STX11, TNFSF14, TNFSF9, RIPK2, IL1RL2, IL18R1, VNN1, BCL10, AP3D1, TNFSF18, SOCS6, SOX13, EBI3, IKZF1, BATF, TNFSF13B, MALT1, SPINK5, GLMN, HHLA2, CORO1A, VSIG4 |
1356 | GO:0002065 | 0.00 | 2.93 | 33.39 | 54 | 80 | columnar/cuboidal epithelial cell differentiation | ARNTL, ATOH1, ATP2B2, BAD, BCL2, PRDM1, BMP4, BMP6, KLF5, CDK6, CDKN1A, CDX2, CUX1, DLX3, EDN3, EDNRB, EMX1, FGF8, GATA4, GATA6, GFI1, GNAQ, HIF1A, HES1, RBPJ, IL13, KIT, MEN1, KITLG, CITED1, PDPK1, PROX1, RAB27A, RAC1, RARA, RARB, RFX3, RHEB, RXRA, SOD1, SOX4, SOX10, SOX11, TYMS, TYRP1, CLRN1, WNT11, TP63, USP13, SLC9A3R1, CLOCK, ZEB2, SEC24B, AGR2 |
1357 | GO:0032508 | 0.00 | 2.92 | 15.44 | 25 | 37 | DNA duplex unwinding | ANXA1, ATRX, CHD1, CHD2, CHD3, CHD4, DDX1, DDX3X, DHX9, DDX11, ERCC3, HMGA1, PURA, RAD51, SUPV3L1, WRN, CDC45, RECQL5, RECQL4, CHD1L, GINS1, RAD50, G3BP1, RUVBL2, ASCC3 |
1358 | GO:0019233 | 0.00 | 2.92 | 17.90 | 29 | 43 | sensory perception of pain | AQP1, CACNA1E, CDK5, CHRNB2, CNR1, CNR2, DLG2, EDNRA, EPHB1, FYN, GIP, IAPP, ITGA2, KCNA1, KCNA2, KCND2, NTRK1, P2RX4, P2RX7, P2RY1, P2RY2, PAWR, PENK, MAPK3, PTGS1, SCN3A, SCN10A, TAC1, TRPV1 |
1359 | GO:0050920 | 0.00 | 2.91 | 39.65 | 64 | 95 | regulation of chemotaxis | ADAM10, AKT2, ANGPT2, BMPR2, C1QBP, C5, CD74, CCR1, CMKLR1, S1PR1, LPAR1, EDN2, EDN3, EDNRA, EFNB2, F2RL1, F3, F7, FGF1, GAS6, CXCL1, CXCL2, CXCL3, HRG, HSPB1, IL1B, ITGA2, KDR, SMAD3, NTF3, NTRK3, SERPINE1, PF4, PF4V1, PRKCA, PRKD1, RAC1, RAC2, CCL21, CXCL6, CXCL5, XCL1, CX3CL1, SEMA3F, ST6GAL1, VEGFA, VEGFB, VEGFC, SCG2, SEMA3B, TNFSF14, TNFSF18, USP14, SLIT2, CXCL14, SEMA3E, SEMA3A, CREB3, SEMA6C, SEMA6B, SEMA4F, SEMA4B, CXCL13, TBR1 |
1360 | GO:0006879 | 0.00 | 2.91 | 16.69 | 27 | 40 | cellular iron ion homeostasis | ABCB7, ACO1, ALAS2, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, BMP6, CP, FTL, HIF1A, HPX, IREB2, LTF, NUBP1, SLC11A2, SLC11A1, SOD1, ATP6V0E1, ATP6V0D1, ATP6V1F, ABCG2, ATP6V1G1, HEPH, ABCB6 |
1361 | GO:0007189 | 0.00 | 2.91 | 17.95 | 29 | 43 | adenylate cyclase-activating G-protein coupled receptor signaling pathway | ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADORA2A, ADRA1B, ADRA2C, ADRB2, CALCR, FSHR, GALR1, GHRH, GHRHR, GNAL, GNAQ, GNAS, GNB1, GPR3, GPR26, PDE4D, PTHLH, PTH1R, VIP, S1PR4, GPR52, SLC9A3R1, RAPGEF2, CALCRL |
1362 | GO:0032411 | 0.00 | 2.91 | 17.95 | 29 | 43 | positive regulation of transporter activity | ACTN4, ATP1B3, BMP4, CALM3, CFTR, CTSS, DNM2, GSTM2, KCNJ11, NTSR1, RELN, PTAFR, RYR2, S100A1, SGK1, SLC9A1, SUMO1, HAP1, RGN, SYNGR3, GSTO1, AKAP7, AKAP6, KCNE2, KCNE3, SGK2, AKAP9, TRDN, RAPGEF3 |
1363 | GO:0002252 | 0.00 | 2.90 | 27.05 | 44 | 66 | immune effector process | ACTB, ACTG1, ADA, CD3G, CDC42, CRP, CX3CR1, GPR183, FCGR2A, FCN1, FCN2, GRB2, CFHR1, HSP90AA1, HSP90AB1, ITGAL, ITPR1, ITPR2, ITPR3, KRT1, LIMK1, CD180, PIK3CB, PRKCE, MAPK3, PTGER4, RELB, SLAMF1, TSC1, TYROBP, EOMES, IL18R1, ABI1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, WASF2, VAV3, BAIAP2, ARPC1A, VSIG4 |
1364 | GO:0090130 | 0.00 | 2.90 | 58.43 | 94 | 140 | tissue migration | AAMP, ACTA2, ACVRL1, AGTR2, ALOX12, ANGPT1, ANGPT2, ANXA3, APOA1, APOH, AQP1, BMP4, BMPR2, KRIT1, SCARB1, CD63, DCN, DPP4, HBEGF, EFNA1, EFNB2, EGR3, EPHA2, EMP2, ETS1, FAP, FGF1, FGF7, FGF8, FLT4, GATA3, GPLD1, GPX1, HAS2, HIF1A, NR4A1, HRG, HSPB1, IFNG, INSL3, ITGA2, ITGA3, ITGB1, JUN, KDR, KIT, KRT2, KRT16, TACSTD2, ENPP2, PDPK1, SERPINF1, PFN1, PFN2, PRCP, PRKCA, PRKCE, PRKD1, PRKX, PROX1, PTPRM, PTPRR, RAB13, RREB1, S100A2, S100P, SOX9, SP100, SPARC, SRF, STC1, T, TAC1, NR2F2, NR2E1, VEGFA, VEGFC, VIL1, SCG2, TNFSF12, ADAM9, RAB11A, NRP2, ITGB1BP1, KLF4, SLIT2, BCAR1, ZEB2, HDAC6, PDCD6, SEMA3A, CXCL13, GIPC1, STRAP |
1365 | GO:0022414 | 0.00 | 2.90 | 26.32 | 43 | 65 | reproductive process | ABAT, ADRA2C, AMBP, APLP2, STS, BYSL, CD38, COL16A1, DHODH, DLG1, GIP, GNAS, IGF2, IGFBP2, IGFBP5, IDO1, INSL4, INSRR, ITGA2, PAPPA, PBX1, PGF, PI3, PSG2, PSG3, PSG5, PSG6, PSG9, PSG11, PTGDR, PTHLH, PZP, RLN1, SEPP1, STAT3, SULT1E1, UCN, EIF4H, RQCD1, RAMP2, DMRT2, CORIN, SLC38A3 |
1366 | GO:0048706 | 0.00 | 2.89 | 21.70 | 35 | 52 | embryonic skeletal system development | ACVR2A, ALX3, BMP4, RUNX2, COL1A1, COL2A1, COL11A1, DLG1, EXT1, EYA1, FGF9, GNAS, HOXC11, HOXD3, HOXD4, HOXD11, IHH, SMAD3, PBX1, PCSK5, PRRX1, SHH, SIX1, SOX11, SP1, SP3, T, TULP3, TWIST1, WNT11, DLK1, IRX5, DEAF1, DMRT2, SIX2 |
1367 | GO:0010817 | 0.00 | 2.89 | 13.53 | 22 | 33 | regulation of hormone levels | ACVR2B, AGTR2, AQP1, BCAT2, CAMK2G, IL1RN, PTPRN, PTPRN2, RAB1A, RAF1, SLC22A1, STXBP3, SERPINA7, HNF1A, VIP, FZD4, LTBP4, SNAP23, RAB11B, EIF2AK3, RIMS2, CPLX1 |
1368 | GO:0061564 | 0.00 | 2.88 | 182.62 | 290 | 438 | axon development | ABL2, ACTB, ACTG1, ADAM10, ADCY1, AP2A1, AP2B1, ANGPT1, APBB1, APC, APOA1, ARHGAP4, ATOH1, BCL2, BMPR2, TSPO, CACNA1A, CACNA1F, CACNA1S, CACNB4, CALM3, CALU, CAMK2A, CAMK2G, CCK, CD72, CDC42, CDK5, CHN1, CHRNB2, AP2M1, AP2S1, CLTA, CNP, COL2A1, COL3A1, COL4A3, COL4A4, COL4A5, COL5A1, COL5A2, COL6A2, COL6A3, COL9A1, COL9A3, CSF2, CSF2RB, CSNK2A1, CSNK2A2, CTNNA1, CTNNA2, DCC, DCX, DHFR, DLG1, DLG3, DLX5, DNM1, DNM2, DPYSL3, HBEGF, ECM2, DUSP5, DUSP7, DUSP9, EFNA1, EFNA3, EFNA4, EFNA5, EFNB2, EGR2, EPHA2, CTTN, EPHA1, EPHA5, EPHA7, EPHA8, EPHB1, ERBB2, EREG, ETV1, ETV4, EXT1, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FYN, GAP43, GATA3, GDI1, GDNF, GFRA1, GOLGA4, GPC1, GRB2, GRIN2A, ARHGAP35, NRG1, HSPA8, HSP90AA1, HSP90AB1, TNC, IL2RA, IL2RB, IL2RG, ILK, ISL1, ITGA1, ITGA2, ITGA5, ITGA9, ITGAV, ITGB1, JUN, KIF5A, KIT, KRAS, ABLIM1, LIMK1, MARK3, RAB8A, KITLG, NRAS, NRTN, NTF3, NTRK1, NTRK2, NTRK3, NTN3, OGN, OPHN1, OTX2, PEBP1, PAX2, PPP5C, PRKCQ, MAPK3, PSPN, RELN, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPRA, PTPRM, RAB3A, RAC1, RAC2, RAF1, RASA2, RNF6, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RRAS, RXRA, RYK, S100A6, S100B, SCN5A, SDC2, SDCBP, SEMA3F, ITSN1, SHC1, SHH, SIAH1, SIAH2, SLIT1, SLIT3, SOS1, SOS2, SPAST, SPTA1, SPTB, SRF, CDKL5, STK11, STXBP1, TBCE, NR2E1, TNR, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, VCL, VEGFA, EZR, XK, SEMA3B, FZD3, FGF23, RND2, USP9X, PICALM, CUL3, SEMA7A, CNTNAP1, KLF7, UNC5C, NUMB, PEA15, RAB11A, NRP2, ARHGEF7, PHOX2B, RPS6KA4, KALRN, DCLK1, RPS6KA5, NUMBL, KLF4, NREP, SLIT2, NRXN3, NRXN1, CHST3, PSMF1, AATK, FEZ2, RAPGEF2, SEMA3E, IST1, FARP2, PSMD6, RBX1, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN2, ARPC2, AKAP9, RASA4, PSME3, SPON2, OLFM1, VAV3, BAIAP2, SLC9A6, CAP2, CAP1, STK25, SEMA6C, SEMA6B, SEMA4F, SEMA4B, ATG7, ARPC1A, DPYSL4, TBR1, CHL1, FRS3, VAX1, TWF2 |
1369 | GO:2001056 | 0.00 | 2.88 | 26.71 | 43 | 64 | positive regulation of cysteine-type endopeptidase activity | ALOX12, BAD, BAX, BID, BOK, CASP8, CASP9, CCK, CD14, CDKN2A, COL4A3, CTGF, DDX3X, F2R, F3, HIP1, IFI16, SMAD3, MAP3K5, SLC11A2, PAWR, REST, RPS3, S100A8, S100A9, SNCA, TRAF2, TRADD, RIPK1, CRADD, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR, BCL10, AIFM1, EIF2AK3, TNFSF15, CASP8AP2, PDCD6, BCL2L10, BCL2L11, ARL6IP5 |
1370 | GO:0006518 | 0.00 | 2.87 | 22.25 | 36 | 54 | peptide metabolic process | AEBP1, ANPEP, BGLAP, CGA, TPP1, CLN5, CPA3, CPD, CTNS, CTSG, CTSZ, DPEP1, ENPEP, F7, F10, GAS6, GPX1, GSTM1, GSTM2, GSTZ1, IDH1, LTA4H, PCSK6, PAM, PROC, PROS1, RNPEP, SOD1, TSHB, XPNPEP1, PROZ, PCSK7, GSTO1, ATP6AP2, CORIN, ADAMTS13 |
1371 | GO:0070489 | 0.00 | 2.87 | 98.91 | 158 | 237 | T cell aggregation | ABL2, ADA, ADK, ANXA1, APC, RHOH, BAD, BAX, BCL2, BCL3, BMP4, BMX, ZFP36L2, CAMK4, CASP8, RUNX2, CBLB, CCND3, CD2, CD3D, CD3G, CD4, CD5, CD6, CD7, CD8A, CD28, CD80, CD86, TNFSF8, CD59, CD74, CD151, CDC42, CDK6, CDKN2A, CLC, CTLA4, CXADR, CYLD, CD55, DHPS, DLG1, DPP4, DTX1, EFNB2, EGR3, ERBB2, F2RL1, FCER1G, FLOT2, FLT3, FYN, GATA3, GRB2, HLA-DQA1, HLX, HES1, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF2, IGFBP2, IHH, IL1B, IL2RA, IL10, IL18, IDO1, INS, IRF1, ITGAD, ITGAL, ITPKB, KIT, LMO1, SMAD3, CD46, P2RX7, PAWR, PAX1, PDPK1, PIK3CG, PRKAR1A, PRKCQ, PRKCZ, PSMB10, PTGER4, PTPN6, RAB27A, RAC1, RAC2, RAG1, RAG2, RARA, RELB, RPL22, SATB1, CCL21, XCL1, SFTPD, SHH, SLC11A1, SOD1, SOS1, SOS2, SOX4, SP3, SPN, SPTA1, SRF, STAT5B, STK11, SYK, TRAF2, TSC1, TNFSF4, TNFRSF4, SCGB1A1, VAV1, WNT1, ZP3, FZD5, EOMES, FZD7, FZD8, FOXN1, AP3B1, TNFSF11, PDE5A, STX11, TNFSF14, TNFSF9, RIPK2, IL1RL2, IL18R1, VNN1, BCL10, AP3D1, TNFSF18, SOCS6, SOX13, EBI3, IKZF1, BATF, TNFSF13B, MALT1, SPINK5, GLMN, HHLA2, CORO1A, VSIG4 |
1372 | GO:0009583 | 0.00 | 2.87 | 35.47 | 57 | 85 | detection of light stimulus | ABCA4, APOA1, APOA4, APOC2, OPN1SW, CACNA1F, CACNB4, CALM3, AKR1C4, CHRM1, CLPS, CNGA1, FECH, GPC4, GPC5, FNTA, OPN1MW, GPC3, GNAQ, GNAT1, GNAT2, GNB1, GNGT1, GNGT2, GPC1, GUCA1A, GUCA1B, GUCY2F, GUCY2D, PDC, PDE6G, PRKCA, PRKCQ, RBP1, RBP2, OPN1LW, RCVRN, RGR, RLBP1, RS1, SAG, SDC1, SDC2, SDC4, ELOVL4, TRPC3, TULP1, LRP8, AKR1C3, RGS9, SLC24A1, DHRS3, GUCA1C, SDC3, NR2E3, GPC6, RRH |
1373 | GO:0045619 | 0.00 | 2.87 | 35.47 | 57 | 85 | regulation of lymphocyte differentiation | ADA, ANXA1, AXL, BAD, PRDM1, BMP4, BTK, CAMK4, CD2, CD28, CD80, CD86, CD74, CDKN2A, CTLA4, CYLD, DTX1, EGR3, ERBB2, FLT3, FLT3LG, GAS6, GATA3, HLX, IFNA2, IFNG, IHH, IL1B, IL2RA, INHA, IRF1, ITPKB, CD46, PRKCZ, PTPN6, RAG1, RARA, SHH, SOD1, SOS1, SOS2, STAT5B, SYK, TNFSF4, FOXN1, AP3B1, TNFSF9, RIPK2, IL1RL2, VNN1, AP3D1, PGLYRP1, TNFSF18, SOX13, RNF41, IKZF1, SPINK5 |
1374 | GO:0017157 | 0.00 | 2.87 | 40.48 | 65 | 97 | regulation of exocytosis | AP1G1, ANXA1, ARF1, ATP6AP1, CACNA1A, CDK5, CFTR, F2RL1, FCER1A, FCER1G, FGA, FGG, FGR, B4GALT1, GLRA1, IFNG, IL13, PDPK1, PFN2, SEPT5, PTAFR, RAB3A, RAB3B, RAB27A, RAB27B, RAC2, RALA, RAP1A, REST, SDC1, SDC4, SDCBP, SNCA, SPINK1, STXBP1, STXBP2, STXBP3, SYK, SYN1, SYT1, SYT4, TSG101, VSNL1, ZP3, RAB7A, STAM, DOC2A, VAMP8, CD84, CDK5R2, HAP1, SYT7, RAB9A, STXBP5L, RAB3D, RIMS2, RIMS3, GAB2, PDCD6IP, UNC13B, CPLX2, CPLX1, RAPGEF4, IL1RAPL1, SNF8 |
1375 | GO:0072358 | 0.00 | 2.87 | 99.71 | 160 | 242 | cardiovascular system development | AAMP, ACTA2, ACVRL1, ADRB2, AHR, ALOX12, ANG, ANGPT1, ANGPT2, ANPEP, ANXA2, ANXA3, APOH, KLK3, AQP1, ADGRB2, BAX, BMPR2, BRCA1, KLF5, BTG1, C3, C5, KRIT1, CDX2, CDX4, CHI3L1, CCR3, COL1A1, COL4A3, CSPG4, CTGF, CTH, CX3CR1, DCN, DHCR7, DLX3, TYMP, ECM1, EGR3, EPHA2, ELK3, EMP2, ENPEP, EPHA1, EPHB1, EPHB2, EPHB3, EREG, ETS1, ETV2, F3, FAP, FGF1, FGF6, FGF9, FLT1, FLT4, B4GALT1, GJA4, GPLD1, GPX1, RAPGEF1, GTF2I, HGF, NR4A1, HPGD, HRG, HSPB1, IGF1, IL1A, IL1B, IL18, ITGA5, ITGA7, ITGAV, JUNB, KCNQ1, KDR, KRT1, LAMA5, LLGL2, MEIS1, MEOX2, MFGE8, FOXO4, CITED1, NRCAM, NTRK1, NTRK2, SERPINE1, PDE3B, ENPP2, SERPINF1, PF4, PGF, PIK3CB, PIK3CG, PRRX1, PRCP, PRKCA, PRKCB, PRKD1, PRKX, PTGER4, PTGIS, PTPN14, PTPRB, PTPRM, RAP1A, RRAS, SAT1, CCL24, CX3CL1, SHB, SMARCA2, SP2, SP100, SPINT1, SRPK2, STK11, SYK, TAL1, NR2F2, NR2E1, TNFAIP2, TNFAIP3, VEGFC, VEZF1, FZD5, SCG2, FOSL1, FZD4, FZD8, RECK, FOXN1, SERPINB7, TNFSF12, NRP2, SGPL1, SOCS3, ITGB1BP1, KLF4, SLIT2, NRXN3, NRXN1, QKI, EIF2AK3, RAPGEF2, SEMA3E, CUL7, PDCD6, WASF2, RAPGEF3, VAV3, CXCL13, PDPN, SPINK5, ESM1, GLMN |
1376 | GO:0009416 | 0.00 | 2.86 | 37.28 | 60 | 90 | response to light stimulus | ABL2, ADRA1B, ASNS, ATP1A2, CCND1, BCL2, BCL3, BRCA2, CACNA1E, CAT, CDK5, CDKN2D, CHRNB2, CIRBP, CLU, CTNS, DBH, DNM2, DUSP1, ELK1, ERCC1, ERCC3, ERCC5, ERCC6, FEN1, GPX1, GRIN2A, HMGN1, HMGCR, HMGCS1, HRH1, HRH2, ITGB1, IVL, JUNB, JUND, KIT, KRAS, MEN1, NTRK2, NTS, OGG1, PDE1B, PER1, SERPINB13, PPP1CA, PRKAA1, MAPK8, PTPRZ1, RBM4, SGK1, USF1, WRN, XPA, COPS3, USP2, CLOCK, KIAA0101, DEAF1, RGS14 |
1377 | GO:0002758 | 0.00 | 2.85 | 67.61 | 108 | 162 | innate immune response-activating signal transduction | BIRC3, XIAP, BTK, C1QBP, CALM3, CASP8, CD14, CD86, CD36, CHUK, ATF2, CTSK, CTSS, CYBA, CYLD, DMBT1, DUSP4, DUSP7, ELK1, EP300, F2RL1, FCER1G, FCN1, FYN, GFI1, HCK, ICAM2, IL1B, IRAK1, IRAK2, IRF1, ITGAM, ITPR1, ITPR2, ITPR3, JUN, KRAS, LTF, NRAS, PDPK1, PIK3C3, PPP2R5D, PPP3R1, PRKACA, PRKACB, PRKACG, PRKCE, MAPK3, MAPK8, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RAF1, RELB, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SEC14L1, SKP1, SYK, TNFAIP3, TYRO3, UBB, UBE2D1, UBE2D2, UBE2V1, CUL1, IKBKG, RIPK1, RIPK2, BCL10, PGLYRP1, UBA3, RPS6KA5, PSMF1, NR1D1, PUM1, PSMD6, TRIL, NR1H4, PSME3, TNIP1, CNPY3, MALT1 |
1378 | GO:0000302 | 0.04 | 2.84 | 6.21 | 10 | 15 | response to reactive oxygen species | ALDH3A2, ERCC6, GPX2, GPX3, GPX7, IL1B, PTPRN, SNCA, SCGB1A1, PRDX6 |
1379 | GO:1901987 | 0.03 | 2.83 | 7.46 | 12 | 18 | regulation of cell cycle phase transition | CDKN2A, CENPE, DDB1, ERCC3, PRKCQ, SIX3, SKP1, XPC, CUL1, CDC14A, MAD2L1BP, KNTC1 |
1380 | GO:0006612 | 0.00 | 2.83 | 42.53 | 68 | 102 | protein targeting to membrane | ADORA1, ANXA2, BSG, FAU, GAS6, RPL10A, PRKCI, PTCH1, PEX19, PEX5, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, SDCBP, SRP9, SRP14, SRP19, SRP68, SSR1, SSR3, RPL14, TAOK2, RPL23, PEX16, SPCS2, SEC61B, RPL35, SEC63 |
1381 | GO:0010632 | 0.00 | 2.83 | 17.45 | 28 | 42 | regulation of epithelial cell migration | ACVRL1, AGTR2, ANGPT2, APOH, KRIT1, CD63, DCN, EFNA1, EPHA2, EMP2, FGF1, HRG, TACSTD2, PDPK1, SERPINF1, PFN2, PRCP, PTPRM, PTPRR, SP100, STC1, NR2F2, NR2E1, KLF4, SLIT2, SEMA3A, CXCL13, STRAP |
1382 | GO:0002253 | 0.00 | 2.83 | 119.77 | 190 | 287 | activation of immune response | A2M, ACTB, ACTG1, ADA, BIRC3, XIAP, BAX, BCL2, BLK, BTK, C1QBP, SERPING1, C1QA, C1QB, C1QC, C1S, C3, C5, C8B, CACNA1F, CACNB4, CALM3, CASP8, CBLB, CD3D, CD3G, CD4, CD14, CD28, CD86, CD36, CD38, CD59, CD79B, CDC42, CHUK, CLU, CR1, CR2, ATF2, CTLA4, CTSK, CTSS, CYBA, CYLD, CD55, DMBT1, DUSP4, DUSP7, ELF1, ELK1, EP300, F2RL1, FCER1G, FCGR2A, FCN1, FCN2, FGR, FYB, FYN, GATA3, GFI1, GPLD1, GRB2, HCK, CFHR1, HLA-DQA1, HSP90AA1, HSP90AB1, ICAM2, IFI16, IL1B, IRAK1, IRAK2, IRF1, ITGAM, ITPR1, ITPR2, ITPR3, JUN, KCNN4, KRAS, KRT1, LIMK1, LTF, CD46, NRAS, PAWR, PDE4B, PDE4D, PDPK1, CFP, PHB, PIK3C3, PIK3CB, PPP2R5D, PPP3R1, PRKACA, PRKACB, PRKACG, PRKCB, PRKCE, PRKCQ, MAPK3, MAPK8, PROS1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN6, PTPRJ, RAC1, RAF1, RELB, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SEC14L1, SKP1, STK11, SYK, TNFAIP3, TYRO3, UBB, UBE2D1, UBE2D2, UBE2V1, VAV1, EZR, VTN, LAT2, CUL1, IKBKG, FCN3, RIPK1, RIPK2, BCL10, PGLYRP1, UBA3, RPS6KA5, THEMIS2, PSMF1, BCAR1, NR1D1, PUM1, ELMO1, PSMD6, TRIL, NR1H4, ABI1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, WASF2, PSME3, TNIP1, VAV3, BAIAP2, ARPC1A, RBCK1, CNPY3, MALT1, VSIG4 |
1383 | GO:0050731 | 0.00 | 2.82 | 26.23 | 42 | 63 | positive regulation of peptidyl-tyrosine phosphorylation | ADORA1, ADRA2C, ANGPT1, CCK, CD4, CD80, CD36, CD44, CD74, CSPG4, ACE, EFNA1, EFNA5, EREG, ERCC6, FCER1A, FGF7, GAS6, HGF, NRG1, ICAM1, IGF2, INS, ITGA5, ITGB1, KITLG, NTF3, ENPP2, RELN, PTPN1, PTPRZ1, STK11, SYK, VEGFA, VEGFB, VEGFC, VTN, LRP8, RIPK2, ARHGEF2, ABI1, TNK2 |
1384 | GO:0071222 | 0.00 | 2.82 | 23.73 | 38 | 57 | cellular response to lipopolysaccharide | ABCA1, ARG1, ASS1, AXL, BYSL, TSPO, CD80, CD86, CD36, ENTPD2, CD40, CEBPE, CCR5, CSF2, CX3CR1, EDNRB, GFI1, HIF1A, HMGCS2, ICAM1, IFNG, IL10, P2RY2, SERPINE1, PDE4B, PDE4D, MAPK8, RARA, CCL20, STAR, TNFRSF1B, TNFSF4, OGT, ADAM9, LITAF, NR1D1, SPON2, IL24 |
1385 | GO:1901215 | 0.03 | 2.82 | 7.48 | 12 | 18 | negative regulation of neuron death | ATF4, CDK5, ESR1, IGF1, IL13, SERPINF1, PPP5C, SORL1, STAT3, TRAF2, UCN, IKBKG |
1386 | GO:0035821 | 0.00 | 2.82 | 27.50 | 44 | 66 | modification of morphology or physiology of other organism | APCS, AQP1, BCL2L1, CAV2, CD4, CHD1, EP300, STOM, FBLN1, HPN, ITGAV, JUN, KPNA1, KPNB1, KPNA4, KPNA5, LTF, SMAD3, NTRK3, NUP88, NUP98, PARK2, SERPINB9, PPIB, EIF2AK2, RANBP2, REST, RXRA, SMARCA4, SP1, TYMS, NUP214, AAAS, VAPB, VAPA, RAB9A, NUP155, NUP93, TNIP1, ATG7, RRAGA, NUP50, CPSF4, NUPL2 |
1387 | GO:0046887 | 0.04 | 2.82 | 6.23 | 10 | 15 | positive regulation of hormone secretion | BMP6, EDN3, GALR1, INHA, P2RY1, SOX11, TAC1, TMF1, VAMP8, CARTPT |
1388 | GO:0032526 | 0.01 | 2.82 | 9.98 | 16 | 24 | response to retinoic acid | BMP4, BMP6, CD38, CDKN2D, DUSP1, IGF2R, IGFBP2, OXT, PTCH1, RNF2, RXRA, SOX2, SP100, SREBF1, SLC10A3, TRIM16 |
1389 | GO:0008637 | 0.00 | 2.82 | 12.49 | 20 | 30 | apoptotic mitochondrial changes | SLC25A4, ATP2A1, BNIP3L, CAMK2A, CASP8, CDKN2A, ATF2, EYA2, HK2, PPP2CB, PPP3R1, MAPK8, YWHAG, YWHAH, YWHAZ, DYNLL1, ACAA2, SIVA1, JTB, PIM2 |
1390 | GO:0051209 | 0.04 | 2.81 | 6.24 | 10 | 15 | release of sequestered calcium ion into cytosol | XCR1, HTR2C, ITPR1, ITPR2, ITPR3, P2RX7, RYR3, CCL21, TRPV1, CHERP |
1391 | GO:2001237 | 0.04 | 2.81 | 6.24 | 10 | 15 | negative regulation of extrinsic apoptotic signaling pathway | ACVR1, CTTN, IGF1, ITGA6, ITGAV, SIAH2, SCG2, RB1CC1, PSME3, ZMYND11 |
1392 | GO:0042327 | 0.00 | 2.81 | 238.06 | 373 | 571 | positive regulation of phosphorylation | ABL2, ACVR1, ACVR1B, ACVR2A, ACVR2B, ACVRL1, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADORA1, ADRA1B, ADRA2C, ADRB2, AKT2, ALK, ANG, ANGPT1, ANXA2, AREG, ATM, ATP6AP1, AVP, BAD, BAX, CCND1, BCL2, BMP1, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, C3, C5, CALM3, CAMK2A, CAMK2G, CAV2, CCK, CCNB1, CCNC, CCND3, CCNH, CCNT1, CCNT2, CD4, CD80, CD36, CD40, CD44, CD74, CDC6, CDC42, CDK5, CDK9, CDKN1A, CENPE, CHI3L1, CLU, CCR1, CNTF, CREBL2, CSF2, CSF2RB, CSNK1D, CSPG4, CTF1, CTGF, DAB2, ACE, GADD45A, DLG1, HBEGF, DUSP5, DUSP7, DUSP9, GPR183, ECT2, LPAR1, EDN3, EDNRA, EDNRB, EEF1A2, EFNA1, EFNA5, EMP2, EPHA4, EPHA7, EPHA8, ERBB2, EREG, ERCC6, ERN1, ESR1, F2R, F2RL1, ACSL1, FCER1A, FGA, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FGG, FGR, FLT1, FLT3, FLT3LG, FLT4, FPR1, FSHR, FYN, GAS6, GCG, GDF9, GRB2, RAPGEF1, GRIN2A, GRM1, HCLS1, HGF, NRG1, UBE2K, HMGCR, HPX, PRMT1, HES1, HSP90AB1, HTR2C, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1R, IGF2, IGFBP3, IL1A, IL1B, IL2RA, IL2RB, IL2RG, IL13, IL18, ILK, INHA, IRAK1, ITGA6, IRAK2, ISL1, ITGA1, ITGA5, ITGB1, JUN, KDR, KISS1, KIT, KRAS, LTF, MARK3, MAP3K5, KITLG, MAP3K11, NRAS, NTF3, NTRK1, NTRK2, NTRK3, DDR2, TNFRSF11B, P2RY1, PEBP1, PDE6G, PDE6H, ENPP2, PDPK1, PFKFB2, PFN2, PHB, PIK3CB, PIM1, PIK3CG, PPP5C, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCE, PRKD1, PRKCZ, MAPK3, EIF2AK2, PROX1, RELN, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTGER4, PTPN1, PTPRA, PTPRZ1, RAC1, RAF1, RAP1A, RAP2A, RAP2B, RASA2, RPS3, RPS27A, RYK, S100A12, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SDCBP, ITSN1, SHC1, STIL, SLAMF1, SLC11A1, SNCA, SOD1, SOS1, SOX2, SOX9, SPN, SPTA1, SPTB, STK10, STK11, XCL2, SYK, TNFRSF1A, TNFRSF1B, TP73, TPD52L1, TRAF2, TNFRSF4, UBB, UCN, VEGFA, VEGFB, VEGFC, VTN, WNT1, WNT11, ZNF16, ZP3, LRP8, FZD5, ARHGEF5, FGF23, CDK2AP1, FZD4, FZD7, FZD8, BCAR3, CUL3, OGT, SEMA7A, IKBKG, CAMK1, MAPKAPK5, MADD, TNFSF11, PDE5A, PEA15, RIPK1, ADAM9, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10B, TNFRSF10A, IQGAP1, HDAC3, BCL10, CDK5R2, RPS6KA4, TNFSF18, LATS1, ARHGEF2, BMP15, VAPB, CRLF1, RPS6KA5, ITGB1BP1, GPR55, S1PR2, TAOK2, PSMF1, GDF15, BAG4, CARTPT, TRAF4, RAPGEF2, SLK, RASSF2, RB1CC1, ZEB2, PSMD6, OXSR1, TNFSF15, RBX1, ABI1, TOM1L1, RAD50, AKAP9, RASA4, SORBS3, TNK2, PSME3, ABCA7, RAPGEF3, VAV3, MAD2L2, STK25, ARL6IP5, NRG3, FRS3, MALT1, JTB, COPS8, ERP29, IL24, RBPMS, GLMN, MAP4K5, CHEK2, FZD10, DUSP12, PHB2 |
1393 | GO:0051282 | 0.03 | 2.81 | 7.49 | 12 | 18 | regulation of sequestering of calcium ion | CCR5, XCR1, HTR2C, ITPR1, ITPR2, ITPR3, P2RX7, RYR1, RYR3, CCL21, TRPV1, CHERP |
1394 | GO:0071214 | 0.00 | 2.81 | 43.16 | 69 | 104 | cellular response to abiotic stimulus | ADSS, ATF4, ATM, ATR, BAX, BCL2L1, CALM3, CASP9, CDKN1A, CNGA1, CRY1, CRY2, CRYAB, DDB1, DDB2, DNM2, ECT2, EIF2S1, ELK1, EP300, ERCC4, FNTA, GATA3, GNAT1, GNB1, GNGT1, GPLD1, GRB2, GRM1, GUCA1A, GUCA1B, GUCY2F, GUCY2D, IFI16, IGF1, INSRR, MGMT, PCK1, PDE6G, PPID, PRKCA, PRKCQ, PTAFR, PTN, RAD1, RAD51, RCVRN, REST, RPGR, RS1, SAG, SIPA1, SNAI2, STK11, TP73, WRN, XPC, CUL4B, TP63, RGS9, SLC24A1, AURKB, RAB11B, CLOCK, GUCA1C, RAD51AP1, CERS1, RUVBL2, SLC38A3 |
1395 | GO:0002819 | 0.00 | 2.81 | 26.29 | 42 | 63 | regulation of adaptive immune response | ADA, ANXA1, BTK, C3, CD4, CD28, CD80, CD40, CLC, CR1, FCER1A, FCER1G, FCER2, HLX, HPX, IFNA2, IFNG, IL1B, IL10, IRF1, P2RX7, PRKCQ, PRKCZ, PTPN6, PVR, XCL1, SLC11A1, SPN, TNFAIP3, TRAF2, TNFSF4, UNG, WHSC1, ZP3, FZD5, TNFSF13, RIPK2, TNFSF18, IL1RL1, IL27RA, TNFSF13B, MALT1 |
1396 | GO:0022904 | 0.00 | 2.81 | 26.29 | 42 | 63 | respiratory electron transport chain | ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, COX4I1, COX5B, COX6A1, COX6B1, COX7B, COX7C, COX8A, COX15, DLD, ETFA, ETFDH, GPD1, SDHB, SDHC, SDHD, SNCA, TAZ, UCP1, UQCRB, UQCRC1, UQCRC2, UQCRFS1, UQCRH, SLC25A14, COX7A2L, COX5A, ATP5J2, SLC25A13, COQ7, ATP5H, ATP5L, UQCR11 |
1397 | GO:0016202 | 0.00 | 2.81 | 12.49 | 20 | 30 | regulation of striated muscle tissue development | CAV3, CENPF, CXADR, DDX5, TSC22D3, FGF3, FGF8, KCNK2, SMAD3, NRAS, S100B, SIX1, TP73, TWIST1, COL14A1, HDAC3, CTDP1, HDAC4, NR1D2, USP19 |
1398 | GO:0030183 | 0.00 | 2.81 | 25.04 | 40 | 60 | B cell differentiation | ADA, ATM, BAD, BAX, BCL2, BCL3, PRDM1, BTK, CEBPG, CR2, GPR183, EP300, FLT3, HHEX, ONECUT1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, RBPJ, IL10, INHA, ITGA4, ITGB1, KIT, NTRK1, PTPN6, RAG1, RAG2, SP3, STAT5B, SYK, TPD52, FZD9, VPRBP, HDAC4, IKZF1, MALT1 |
1399 | GO:0019226 | 0.04 | 2.81 | 6.25 | 10 | 15 | transmission of nerve impulse | AVP, CACNA1A, CACNA1E, CACNB4, S1PR1, GLRA1, NRCAM, SOD1, CNTNAP1, CACNG2 |
1400 | GO:0002062 | 0.02 | 2.81 | 8.75 | 14 | 21 | chondrocyte differentiation | BMPR1A, BMPR2, SERPINH1, COL2A1, COL9A1, COL11A1, FGF9, FGFR3, GPLD1, PRKCA, PTH1R, WNT2B, EIF2AK3, ARID5A |
1401 | GO:0042990 | 0.00 | 2.81 | 20.03 | 32 | 48 | regulation of transcription factor import into nucleus | AGTR2, BCL3, CD36, CDH1, CYLD, EDA, FLNA, HCLS1, IL1B, IL10, IL18, SMAD3, TONSL, PPM1A, PPM1B, PPP3R1, PRKCQ, SLC9A1, TRIP6, AKAP1, DYRK2, TNFSF14, IL18R1, HDAC3, AKAP6, LITAF, TRIM28, TACC3, CREB3, CHERP, RBCK1, EDAR |
1402 | GO:0098869 | 0.00 | 2.81 | 12.51 | 20 | 30 | cellular oxidant detoxification | ALB, CAT, GPX1, GPX2, GPX3, GPX7, GSTZ1, HBA1, HBA2, HP, MGST2, PTGS1, S100A9, SEPW1, PXDN, EPX, GSTO1, PRDX6, PRDX4, PRDX3 |
1403 | GO:0006305 | 0.00 | 2.81 | 18.78 | 30 | 45 | DNA alkylation | ATRX, BRCA1, DNMT1, TRDMT1, DNMT3A, DNMT3B, GNAS, H3F3B, MGMT, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, FKBP6, HIST1H3F, PICK1, TRIM28, CTCF, BAZ2A |
1404 | GO:0045776 | 0.03 | 2.80 | 7.50 | 12 | 18 | negative regulation of blood pressure | ABAT, ADORA1, BDKRB2, CNR1, GJA5, FFAR3, GUCA2B, OXT, PTAFR, RNPEP, UCN, VEGFC |
1405 | GO:0042632 | 0.01 | 2.80 | 10.01 | 16 | 24 | cholesterol homeostasis | ABCA1, ABCA2, APOA1, APOA4, APOC2, CAV3, SCARB1, CETP, G6PC, HPN, LCAT, ACSM3, SOAT2, LIPG, ABCG1, EHD1 |
1406 | GO:0048844 | 0.05 | 2.80 | 6.25 | 10 | 15 | artery morphogenesis | PRDM1, BMP4, GJA5, HPGD, SMAD7, PRRX1, PTGER4, VEGFA, WNT11, HAND2 |
1407 | GO:0060419 | 0.03 | 2.80 | 7.50 | 12 | 18 | heart growth | AGTR2, CAV3, CXADR, S1PR1, KCNK2, SMAD1, PRKAR1A, TP73, COL14A1, SORBS2, CTDP1, PDLIM5 |
1408 | GO:0034103 | 0.00 | 2.80 | 13.77 | 22 | 33 | regulation of tissue remodeling | ATP6AP1, BAX, BGLAP, CA2, CD38, S1PR1, ERG, FLT4, B4GALT1, HRG, IAPP, IL18, TNFRSF11B, P2RX7, PDK4, PTGER4, SYK, TNFAIP3, VDR, TNFSF11, INPP4B, CARTPT |
1409 | GO:0070059 | 0.00 | 2.80 | 13.77 | 22 | 33 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | ATF4, ATP2A1, BAX, BCL2, CASP4, ERN1, GRINA, UBE2K, ITPR1, MAP3K5, OPA1, PARK2, PTPN1, TRAF2, WFS1, TNFRSF10B, AIFM1, EIF2AK3, BCL2L11, CREB3, SERINC3, ERP29 |
1410 | GO:0035794 | 0.01 | 2.80 | 12.52 | 20 | 30 | positive regulation of mitochondrial membrane permeability | BAD, BAX, BCL2, BID, BNIP3, BNIP3L, CASP8, ATF2, EYA2, SFN, PPP3R1, MAPK8, SLC9A1, YWHAG, YWHAH, YWHAZ, DYNLL1, BCL2L11, ACAA2, SIVA1 |
1411 | GO:0043507 | 0.05 | 2.80 | 6.25 | 10 | 15 | positive regulation of JUN kinase activity | EPHA4, IL1B, RPS3, TRAF2, FZD5, ARHGEF5, FZD4, FZD8, ZEB2, FZD10 |
1412 | GO:0046686 | 0.05 | 2.80 | 6.25 | 10 | 15 | response to cadmium ion | ALAD, ARG1, CAT, DTYMK, GSS, MAPK8, SLC34A1, SORD, SPARC, SLC30A1 |
1413 | GO:0014015 | 0.03 | 2.80 | 7.51 | 12 | 18 | positive regulation of gliogenesis | BIN1, HES1, IL1B, NTF3, PTPRZ1, RHEB, SHH, SOX10, SPINT1, TP73, RNF112, OLIG2 |
1414 | GO:0010812 | 0.01 | 2.80 | 11.27 | 18 | 27 | negative regulation of cell-substrate adhesion | ACTN4, ACVRL1, ANGPT2, ARHGAP6, CDKN2A, COL1A1, FBLN1, TACSTD2, MEN1, SERPINE1, PTPRZ1, TBCD, WNT1, FZD4, FZD7, ADAM15, ITGB1BP1, SEMA3E |
1415 | GO:0046503 | 0.01 | 2.80 | 11.27 | 18 | 27 | glycerolipid catabolic process | APOA1, APOA4, APOC2, APOH, DAGLA, SCARB1, CPS1, FABP2, FABP6, FABP7, GPLD1, LIPE, ENPP2, PIK3CG, PPP1CA, PRKACA, PRKACB, PRKACG |
1416 | GO:0046677 | 0.05 | 2.80 | 6.26 | 10 | 15 | response to antibiotic | CASP8, CASP9, ETS1, HSP90AA1, CIITA, PPP2CB, SOD1, UQCRFS1, UROS, AOC3 |
1417 | GO:0033598 | 0.05 | 2.80 | 6.26 | 10 | 15 | mammary gland epithelial cell proliferation | AREG, BAX, CCND1, CHUK, EPHA2, ESR1, GPX1, RREB1, TNFSF11, DEAF1 |
1418 | GO:0010596 | 0.01 | 2.80 | 10.02 | 16 | 24 | negative regulation of endothelial cell migration | ACVRL1, AGTR2, ANGPT2, APOH, KRIT1, DCN, HRG, SERPINF1, PTPRM, SP100, STC1, NR2F2, ITGB1BP1, KLF4, SLIT2, CXCL13 |
1419 | GO:0042220 | 0.01 | 2.80 | 10.02 | 16 | 24 | response to cocaine | ABAT, ADRA1B, BAX, CDK5, CHRNB2, CNR1, DNM2, DNMT3A, DNMT3B, HTR3A, NTS, OXT, SMPD1, SNCA, TACR3, EFTUD2 |
1420 | GO:0043029 | 0.01 | 2.80 | 10.02 | 16 | 24 | T cell homeostasis | BAX, BCL2, CACNA1F, TSC22D3, IL2RA, LMO1, P2RX7, RAG1, STAT5B, FOXN1, TNFSF14, CCNB2, CHST3, BCL2L11, SIVA1, CORO1A |
1421 | GO:0046456 | 0.01 | 2.80 | 10.02 | 16 | 24 | icosanoid biosynthetic process | ALOX12, ANXA1, AVP, CD74, EDN2, FCER1A, GGT7, HPGD, LTA4H, MGST2, PTGIS, PTGS1, RNPEP, SYK, AKR1C3, PRG3 |
1422 | GO:0002886 | 0.02 | 2.80 | 8.76 | 14 | 21 | regulation of myeloid leukocyte mediated immunity | C3, F2RL1, FCER1A, FCER1G, FGR, IL13, PDPK1, PTAFR, RAC2, STXBP2, SYK, VAMP8, CD84, GAB2 |
1423 | GO:0007339 | 0.02 | 2.80 | 8.76 | 14 | 21 | binding of sperm to zona pellucida | CLGN, B4GALT1, HIST1H1T, OVGP1, SPAM1, TNP2, CCT3, ZAN, ZP2, ZP3, CCT7, CCT4, CCT2, CCT8 |
1424 | GO:0008347 | 0.02 | 2.80 | 8.76 | 14 | 21 | glial cell migration | TSPO, CDK5, VCAN, CSPG4, DCX, EPHA4, EFEMP1, HEXB, P2RY1, RELN, PTPRZ1, NR2E1, LRP8, CDK5R2 |
1425 | GO:0032651 | 0.02 | 2.80 | 8.76 | 14 | 21 | regulation of interleukin-1 beta production | ACP5, APOA1, CASP5, S1PR3, F2R, GHSR, HSPB1, IFI16, IFNG, ISL1, SMAD3, P2RX7, TNFAIP3, TRIM16 |
1426 | GO:0033572 | 0.02 | 2.80 | 8.76 | 14 | 21 | transferrin transport | ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, CLTC, DNM2, SLC11A2, ATP6V0E1, ATP6V0D1, RAB11B, ATP6V1F, ATP6V1G1 |
1427 | GO:0042769 | 0.02 | 2.80 | 8.76 | 14 | 21 | DNA damage response, detection of DNA damage | DDB1, RFC1, RFC2, RFC3, RFC4, RFC5, RPA3, RPS3, RPS27A, SOX4, UBB, CUL4B, CUL4A, RBX1 |
1428 | GO:0051966 | 0.02 | 2.80 | 8.76 | 14 | 21 | regulation of synaptic transmission, glutamatergic | ADORA1, ATP1A2, CNR1, GLUL, GRIK3, NTRK1, NTRK2, OPHN1, RELN, SYT1, TNR, UCN, DGKI, NRXN1 |
1429 | GO:0060324 | 0.02 | 2.80 | 8.76 | 14 | 21 | face development | ALDH1A3, BBS4, COL1A1, DLX5, ITGA4, PAX9, MAPK3, RAF1, RARA, RRAS, SOX3, SRF, ALDH1A2, SGPL1 |
1430 | GO:0001662 | 0.03 | 2.80 | 7.51 | 12 | 18 | behavioral fear response | BCL2, CACNA1E, CCK, DBI, DPP4, EIF4E, EIF4G1, HTR2C, PENK, NR2E1, UCN, DEAF1 |
1431 | GO:0002042 | 0.03 | 2.80 | 7.51 | 12 | 18 | cell migration involved in sprouting angiogenesis | EFNB2, EGR3, GPLD1, NR4A1, ITGB1, KDR, SRF, NR2E1, VEGFA, ITGB1BP1, KLF4, SLIT2 |
1432 | GO:0006007 | 0.03 | 2.80 | 7.51 | 12 | 18 | glucose catabolic process | ALDOB, ALDOC, BAD, ENO2, GAPDH, HK2, LDHA, PFKFB2, PFKFB4, PGAM2, PGK1, PPP2R5D |
1433 | GO:0007616 | 0.03 | 2.80 | 7.51 | 12 | 18 | long-term memory | ADCY1, CAMK4, CTNS, GRIA1, NTF4, NTRK2, PRKCZ, RELN, SGK1, SRF, TAC1, RGS14 |
1434 | GO:0008299 | 0.03 | 2.80 | 7.51 | 12 | 18 | isoprenoid biosynthetic process | ALDH1A3, DPAGT1, FDFT1, FDPS, HMGCR, HMGCS1, HMGCS2, RBP1, AKR1C3, ALDH1A2, GGPS1, DHRS9 |
1435 | GO:0014888 | 0.03 | 2.80 | 7.51 | 12 | 18 | striated muscle adaptation | CACNA1S, CAMK2G, GATA4, GATA6, GTF2I, IGFBP5, TNNC1, TNNT1, TRPC3, CFLAR, KDM4A, HDAC4 |
1436 | GO:0030857 | 0.03 | 2.80 | 7.51 | 12 | 18 | negative regulation of epithelial cell differentiation | ACVRL1, CCND1, S1PR3, HES1, IFNG, IL13, CITED1, REG3A, SALL1, SRSF6, SOX9, TP63 |
1437 | GO:0044246 | 0.03 | 2.80 | 7.51 | 12 | 18 | regulation of multicellular organismal metabolic process | BMP4, CTGF, F2R, FAP, IHH, ITGA2, ITGB1, CIITA, RAP1A, UCN, SERPINB7, RAPGEF3 |
1438 | GO:0045744 | 0.03 | 2.80 | 7.51 | 12 | 18 | negative regulation of G-protein coupled receptor protein signaling pathway | ADA, ADRB2, ADRBK1, BICD1, CRY1, DNM1, DNM2, GRK6, RGS2, RGS13, SNCA, GPRASP1 |
1439 | GO:0046794 | 0.03 | 2.80 | 7.51 | 12 | 18 | transport of virus | BST2, CAV2, EPS15, IFIT1, KPNA1, KPNB1, RAN, RPS27A, DYNLT1, TSG101, UBB, ALYREF |
1440 | GO:0050974 | 0.03 | 2.80 | 7.51 | 12 | 18 | detection of mechanical stimulus involved in sensory perception | ATP2B2, COL11A1, FYN, HPN, IGF1, ITGA2, KCNA1, KIT, NTRK1, PAWR, SLC12A2, SOX2 |
1441 | GO:1902042 | 0.03 | 2.80 | 7.51 | 12 | 18 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | BRCA1, FGA, FGG, GPX1, HGF, ICAM1, SERPINE1, RAF1, TNFAIP3, PEA15, CFLAR, ARHGEF2 |
1442 | GO:1902579 | 0.03 | 2.80 | 7.51 | 12 | 18 | multi-organism localization | BST2, CAV2, EPS15, IFIT1, KPNA1, KPNB1, RAN, RPS27A, DYNLT1, TSG101, UBB, ALYREF |
1443 | GO:0000303 | 0.05 | 2.80 | 6.26 | 10 | 15 | response to superoxide | APOA4, CD36, DHFR, ERCC6, FANCC, SOD1, SOD2, PRDX2, RGN, FBLN5 |
1444 | GO:0001731 | 0.05 | 2.80 | 6.26 | 10 | 15 | formation of translation preinitiation complex | EIF2S3, EIF3E, DENR, EIF3A, EIF3B, EIF3D, EIF3F, EIF3G, EIF3J, EIF3M |
1445 | GO:0002446 | 0.05 | 2.80 | 6.26 | 10 | 15 | neutrophil mediated immunity | ANXA3, CTSG, ACE, F2RL1, PTAFR, STXBP2, STXBP3, SYK, STX11, TUSC2 |
1446 | GO:0003338 | 0.05 | 2.80 | 6.26 | 10 | 15 | metanephros morphogenesis | AGTR2, BMP4, GDNF, HES1, CITED1, PAX2, SALL1, SOX9, PAX8, SIX2 |
1447 | GO:0007257 | 0.05 | 2.80 | 6.26 | 10 | 15 | activation of JUN kinase activity | ERCC6, ERN1, FCER1A, MAP3K5, MAP3K11, PTPN1, SYK, TNFSF11, RIPK1, MAP4K5 |
1448 | GO:0007520 | 0.05 | 2.80 | 6.26 | 10 | 15 | myoblast fusion | CACNA1S, CAV3, CD53, FLT3LG, WNT1, TNFSF14, CFLAR, DYRK1B, GDF15, EHD1 |
1449 | GO:0010543 | 0.05 | 2.80 | 6.26 | 10 | 15 | regulation of platelet activation | ABAT, ADRB2, ALOX12, FCER1G, HRG, PRKCA, PRKCQ, PRKG1, SELP, SYK |
1450 | GO:0016601 | 0.05 | 2.80 | 6.26 | 10 | 15 | Rac protein signal transduction | ARF6, DNM2, EPS8, KRAS, OGT, WASF1, ELMO1, FARP2, ABI2, WASF2 |
1451 | GO:0031112 | 0.05 | 2.80 | 6.26 | 10 | 15 | positive regulation of microtubule polymerization or depolymerization | APC, ARL2, CAV3, RGS2, RPS3, CLIP1, SPAST, KATNB1, TUBGCP3, STMN2 |
1452 | GO:0032965 | 0.05 | 2.80 | 6.26 | 10 | 15 | regulation of collagen biosynthetic process | BMP4, CTGF, F2R, IHH, ITGA2, CIITA, RAP1A, UCN, SERPINB7, RAPGEF3 |
1453 | GO:0035767 | 0.05 | 2.80 | 6.26 | 10 | 15 | endothelial cell chemotaxis | EGR3, FGF1, NR4A1, HRG, HSPB1, KDR, PRKD1, RAB13, VEGFA, CXCL13 |
1454 | GO:0050427 | 0.05 | 2.80 | 6.26 | 10 | 15 | 3'-phosphoadenosine 5'-phosphosulfate metabolic process | ENPP1, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, SULT2A1, PAPSS2, PAPSS1, SLC26A1 |
1455 | GO:0050892 | 0.05 | 2.80 | 6.26 | 10 | 15 | intestinal absorption | ACO1, APOA1, APOA4, CD36, SCARB1, KCNQ1, VDR, VIL1, EZR, SOAT2 |
1456 | GO:0061615 | 0.05 | 2.80 | 6.26 | 10 | 15 | glycolytic process through fructose-6-phosphate | ALDOB, ALDOC, ENO2, GAPDH, HK2, PFKFB2, PFKFB4, PGAM2, PGK1, PPP2R5D |
1457 | GO:0061621 | 0.05 | 2.80 | 6.26 | 10 | 15 | canonical glycolysis | ALDOB, ALDOC, ENO2, GAPDH, HK2, PFKFB2, PFKFB4, PGAM2, PGK1, PPP2R5D |
1458 | GO:0070229 | 0.05 | 2.80 | 6.26 | 10 | 15 | negative regulation of lymphocyte apoptotic process | ADA, BMP4, CD74, TSC22D3, HIF1A, IDO1, PRKCQ, RAG1, BCL10, AURKB |
1459 | GO:0032103 | 0.00 | 2.80 | 39.50 | 63 | 95 | positive regulation of response to external stimulus | ADAM10, ADRB2, AKT2, APOH, BMP6, BMPR2, BNIP3, BNIP3L, C1QBP, CD74, CCR1, CMKLR1, CYBA, CYP27B1, DCN, S1PR1, LPAR1, EDN2, EDN3, F2RL1, F3, F7, GAS6, GHSR, CXCL1, CXCL2, CXCL3, HIF1A, HRG, HSPB1, KDR, CD180, SMAD3, NTF3, NTRK3, PAFAH1B2, PF4, PF4V1, PGC, PIP4K2A, PRKD1, KLK7, RAC1, RAC2, CCL21, CXCL6, CXCL5, USF1, VEGFA, VEGFB, VEGFC, SCG2, EPM2A, BECN1, TNFSF14, SLIT2, ATG5, CXCL14, PUM1, CREB3, ATG7, SPTLC1, CXCL13 |
1460 | GO:0007050 | 0.00 | 2.79 | 30.69 | 49 | 74 | cell cycle arrest | APBB1, APC, BARD1, DST, CDK6, CDKN2C, CDKN2D, BRINP1, GADD45A, DHCR24, DUSP1, E4F1, EIF4G2, ERN1, GAS1, GAS2, GAS6, IFNG, IFNW1, ILK, INHA, IRF1, SMAD3, PA2G4, PPM1A, PPM1G, PRKAA1, PRKAB2, RB1, RHEB, SOX2, STK11, TSC1, TSC2, TSG101, CUL5, CUL4A, CUL3, CUL2, CUL1, CDC14A, KAT2B, CDC123, GAS2L1, KHDRBS1, CGRRF1, CGREF1, RRAGA, WDR6 |
1461 | GO:0030522 | 0.00 | 2.79 | 65.52 | 104 | 157 | intracellular receptor signaling pathway | ACTN4, NR0B1, AHR, ALOX15B, BIRC3, XIAP, ARNT, ARNTL, BCL2, BCL2L1, BRCA1, C1QBP, CASP8, CCNE1, CHUK, CRY1, CRY2, CYLD, CYP24A1, CYP27B1, DAB2, DDX5, DEFA1, EP300, ESR1, ESRRG, FLT1, NR5A1, NR6A1, GHRHR, NR4A1, HNF4G, PRMT2, HSP90AB1, IGF1, IRAK1, IRAK2, ISL1, SCGB2A1, CNOT2, P2RX7, PER1, PGR, PHB, PIM1, PPP5C, PRCP, PTGIS, RAN, RARA, RARB, RB1, RNF6, RPS27A, RXRA, RXRG, SAFB, SEC14L1, SKP2, SNAI2, SMARCA4, SP100, STAT3, TAF7, NR2F1, NR2F2, TNFAIP3, NR2C1, TWIST1, UBB, UBE2V1, UBE3A, NR1H2, VDR, YWHAH, NRIP1, IKBKG, AKR1C3, RIPK2, TRIM24, ALDH1A2, NR1I2, BUD31, PSTPIP1, RQCD1, DHRS3, TRIP4, NR1D1, CLOCK, PUM1, ZNF536, NR1I3, NR1H4, NR1D2, NR2E3, HDAC6, CITED2, RBM14, CARM1, TRIM16, TXNIP, STARD10, BRD8, PHB2 |
1462 | GO:0009152 | 0.00 | 2.79 | 35.77 | 57 | 86 | purine ribonucleotide biosynthetic process | ABCA1, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADCYAP1R1, ADORA2A, ADRB2, AK2, AK4, AMPD1, AMPD2, APLP1, AVP, AVPR2, CALCR, CALM3, LPAR1, EDNRA, EDNRB, FSHR, GALR1, GCG, GHRH, GHRHR, GLP1R, GNAI3, GNAL, GNAS, GRM8, GUK1, HPRT1, IMPDH1, IMPDH2, INSL3, NTRK1, NTRK2, P2RY11, PRKCA, PTGER4, PTHLH, RAF1, UCN, VIP, VIPR2, WFS1, PAPSS2, PAPSS1, AKAP6, GABBR2, CALCRL, RAMP2, CAP2, CAP1, SLC26A1, ACOT7 |
1463 | GO:0090068 | 0.00 | 2.78 | 31.99 | 51 | 77 | positive regulation of cell cycle process | ATM, ATRX, BRCA1, CCNB1, CDKN1A, CDKN2A, CTGF, FAP, GATA6, MAD2L1, FOXO4, ORC1, PRKACA, PROX1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SFPQ, SOX4, TP73, UBB, RNF112, CRADD, PSMF1, PSMD6, PSME3, USP19 |
1464 | GO:0045860 | 0.00 | 2.78 | 80.52 | 128 | 195 | positive regulation of protein kinase activity | ACVR2B, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADORA1, ADRB2, ANG, ANGPT1, BAX, BMP4, CAMK2A, CAMK2G, CD4, CDK5, CDKN1A, CENPE, CLU, CSF2, CSF2RB, ACE, DLG1, HBEGF, ECT2, EFNA5, EMP2, EREG, F2R, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FYN, GAS6, GCG, GRB2, RAPGEF1, GRIN2A, NRG1, IL2RA, IL2RB, IL2RG, INS, MARK3, NRAS, NTRK1, DDR2, PEBP1, PDPK1, PPP5C, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCZ, EIF2AK2, RELN, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPRA, RAF1, RAP1A, RASA2, CCL21, SDC4, SLC11A1, SOS1, SPTA1, SPTB, STK10, STK11, UCN, WNT11, ZP3, LRP8, FGF23, CUL3, ADAM9, VAPB, ITGB1BP1, TAOK2, PSMF1, CARTPT, SLK, RASSF2, PSMD6, OXSR1, RBX1, ABI1, TOM1L1, AKAP9, RASA4, PSME3, STK25, NRG3, FRS3, JTB |
1465 | GO:1901615 | 0.00 | 2.78 | 15.59 | 25 | 38 | organic hydroxy compound metabolic process | ABAT, AOC2, ATP2B2, BCL2, CHRNB2, CRYM, DIO1, DIO2, GRIN2A, HIF1A, HPN, HPRT1, LDHA, PARK2, PDE1B, PFKFB2, SLC5A5, SLC22A5, SNCB, SRD5A1, SULT1A1, SULT1A3, TACR3, PAX8, SNCAIP |
1466 | GO:1904589 | 0.00 | 2.78 | 38.39 | 61 | 92 | regulation of protein import | AGTR2, ANGPT1, BCL3, BMP4, BMP6, BMPR1A, BRCA1, CD36, CDH1, CDKN1A, CYLD, DAB2, ECT2, EDA, EMD, FLNA, GAS6, GNAQ, HCLS1, HSPA8, HSP90AB1, IGF1, IL1B, IL10, IL18, JUP, KPNA1, IPO5, SMAD3, TONSL, OGG1, PPM1A, PPM1B, PPP3R1, PRKCQ, SFRP5, SHH, SLC9A1, SNAI2, TRIP6, ZIC1, ARHGEF5, AKAP1, FZD7, DYRK2, TNFSF14, IL18R1, HDAC3, SLC9A3R1, AKAP6, CABP1, LITAF, TRIM28, NUTF2, APC2, TACC3, CREB3, CHERP, RBCK1, EDAR, RBPMS |
1467 | GO:0006954 | 0.00 | 2.77 | 64.71 | 103 | 157 | inflammatory response | ADORA2A, PARP4, AGTR2, AOX1, AXL, BMP6, CAMK4, CD5L, CD14, TNFRSF8, CD40, ADGRE5, CDO1, CHI3L1, CHUK, CCR1, CCR3, CCR5, ACKR2, LTB4R, CYBA, ECM1, S1PR3, ELF3, F2RL1, FPR2, ACKR1, XCR1, CXCL1, CXCL2, CXCL3, HRH1, IFI16, IFNA2, RBPJ, IL1RAP, IL13, TNFRSF9, IRAK2, ITGAL, KIT, KNG1, KRT16, LIPA, LTA4H, CD180, SMAD1, NTRK2, OLR1, TNFRSF11B, P2RX7, PF4, PF4V1, PIK3CB, PRKD1, PRKCQ, PRKCZ, PTAFR, PTGDR, PTGS1, RAC1, RELB, RXRA, CCL20, CCL21, CCL22, CCL25, CXCL6, CXCL5, SDC1, SELP, SLC11A1, SIGLEC1, SP100, SYK, TP73, TNFRSF4, UCN, SCG2, ATRN, TPST1, IKBKG, AOC3, RIPK2, TNFRSF6B, SNAP23, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, IL18RAP, RPS6KA4, PSTPIP1, RPS6KA5, THEMIS2, HDAC4, TRIL, TSPAN2, CHST4, CXCL13, CXCR6, IL24, TUSC2 |
1468 | GO:0001568 | 0.00 | 2.75 | 108.41 | 171 | 261 | blood vessel development | AAMP, ACVR1, ADRB2, AHR, ALOX12, ANG, ANPEP, ANXA2, ANXA3, APOH, KLK3, ADGRB2, BAX, BRCA1, KLF5, BTG1, C3, C5, CASP8, KRIT1, CDC42, CDX2, CDX4, CHI3L1, CCR3, COL1A1, COL4A3, COL5A1, CSPG4, CTGF, CX3CR1, DCN, DHCR7, DLX3, TYMP, ECM1, S1PR1, EDNRA, EFNA1, EFNB2, EGR3, EPHA2, ELK3, EMP2, ENPEP, EPHA1, EPHB1, EPHB2, EPHB3, ERBB2, EREG, ETS1, ETV2, F3, FAP, FGF1, FGF6, FGF9, FLT1, FLT4, GATA4, B4GALT1, GJA4, GPLD1, GPX1, RAPGEF1, GTF2I, HAS2, HGF, HHEX, HIF1A, NR4A1, HRG, HSPB1, IHH, IL1A, IL1B, IL18, ISL1, ITGA5, ITGA7, ITGAV, ITGB1, JUN, JUNB, KDR, KRT1, LAMA5, LLGL2, MEIS1, MEOX2, MFGE8, FOXO4, CITED1, NRCAM, NTRK1, NTRK2, SERPINE1, PDE3B, ENPP2, SERPINF1, PF4, PGF, PIK3CB, PIK3CG, PRCP, PRKCA, PRKCB, PRKD1, PRKX, PTGIS, PTN, PTPRB, PTPRJ, PTPRM, RAP1A, RRAS, SAT1, CCL24, CX3CL1, SHB, SHC1, SP100, SPARC, SPINT1, SRPK2, SYK, T, TAL1, NR2F2, NR2E1, TNFAIP2, TNFAIP3, TNNI3, TWIST1, VEGFC, WNT2, VEZF1, FZD5, SCG2, FOSL1, FZD4, FZD8, RECK, FOXN1, TNFSF12, ADAM15, NRP2, ALDH1A2, SGPL1, SOCS3, ITGB1BP1, KLF4, SLIT2, NRXN3, NRXN1, HAND1, QKI, EIF2AK3, RAPGEF2, SEMA3E, CUL7, PDCD6, WASF2, CALCRL, RAMP2, VAV3, CXCL13, SPINK5, ESM1, GLMN |
1469 | GO:1903706 | 0.00 | 2.75 | 19.47 | 31 | 47 | regulation of hemopoiesis | ADA, AXL, BAD, PRDM1, BTK, CD2, CD28, CD80, CD86, ACE, EGR3, FLT3LG, GAS6, GATA3, IL1B, IL2RA, CD46, PRKCZ, PTPN6, RAG1, SOD1, SYK, FOXN1, AP3B1, TNFSF9, RIPK2, IL1RL2, VNN1, AP3D1, SOX13, SPINK5 |
1470 | GO:0007417 | 0.00 | 2.75 | 18.71 | 30 | 46 | central nervous system development | ACVR1B, ADORA2A, ALDH3A2, BTD, TPP1, COL2A1, COX7B, VCAN, ATN1, RCAN1, GABRA4, JARID2, MAL, NRCAM, PAM, PARK2, PCP4, SERPINI1, PSPN, KLK6, RPS6KA3, SEMA3F, SIX1, UGT8, RNF103, PAX8, JRKL, VNN2, VNN1, WWP1 |
1471 | GO:0001501 | 0.00 | 2.75 | 83.59 | 132 | 201 | skeletal system development | ACP2, ACP5, ACVR2B, ACVRL1, AEBP1, AES, AHSG, ANXA2, ARSE, ATP6AP1, BBS2, BGLAP, BMP1, BMP6, BMP8B, BMPR1A, BMPR2, CACNA1S, SERPINH1, CD44, CDX1, CHAD, CHI3L1, CMKLR1, COL3A1, COL5A2, COL9A1, COL10A1, COL12A1, COL19A1, COMP, VCAN, CTGF, DLX5, DLX6, EPHA2, EN1, EP300, ESR1, ETS2, EVC, EXTL1, FBN1, EFEMP1, FGF6, FGF8, FGFR3, FLI1, GJA5, GNAQ, GPLD1, HAS2, HEXB, HIF1A, HOXC10, HOXD8, IDUA, IGF1, IGF2, INHA, INPPL1, INSIG1, KIT, LTF, LUM, SMAD1, MATN3, MEIS1, TNFRSF11B, P2RX7, PAX1, PHEX, PIP4K2A, PPIB, PRKCA, MAPK3, PTGER4, PTHLH, PTH1R, PTPN6, RARA, RARB, RPL38, RPS6KA3, RYR1, SNAI2, SNAI1, SOX4, SOX5, SOX9, SPARC, SRD5A1, SRF, STC1, TAL1, KLF10, CLEC3B, TRPS1, TYMS, TYROBP, UFD1L, VDR, WHSC1, WNT1, WNT2B, PRKRA, TNFSF11, TP63, DCHS1, CHRD, SGPL1, PAPSS2, PAPSS1, RGN, DHRS3, CER1, HAND1, EIF2AK3, HAND2, ADAMTS4, IFT140, HDAC4, RASSF2, SETDB1, ABI1, WASF2, LRRC17, CARM1, EBP, RAI1, ARID5A, ADAMTS7 |
1472 | GO:0050727 | 0.00 | 2.74 | 18.24 | 29 | 44 | regulation of inflammatory response | A2M, AHSG, ANXA1, BIRC3, XIAP, C1QBP, SERPING1, C5, C8B, CASP4, CASP5, CD59, CR1, CD55, EDNRB, HCK, IL1R1, CD46, PER1, CFP, PHB, PROS1, PSMA6, SELE, SCGB1A1, VTN, SEMA7A, IL1RL2, NR1D2 |
1473 | GO:0002504 | 0.00 | 2.74 | 24.62 | 39 | 59 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | AP2A1, AP2B1, AP1G1, ARF1, CD74, CENPE, AP2M1, AP1S1, AP2S1, CLTA, CLTC, CTSD, CTSE, CTSV, CTSS, DYNC1H1, DYNC1I1, DYNC1I2, DNM2, FCER1G, HLA-DQA1, KIF5A, KLC1, RAB7A, DYNLL1, CTSF, AP1S2, AP1M1, KIF3B, AP1M2, ACTR1B, ACTR1A, SEC24B, IFI30, SEC23A, DCTN6, SEC24A, KIF3A, DCTN3 |
1474 | GO:0031638 | 0.00 | 2.74 | 22.09 | 35 | 53 | zymogen activation | BAD, BAX, BID, BOK, CASP8, CASP9, CCK, CD14, CDKN2A, COL4A3, F2R, F3, HIP1, IFI16, SMAD3, SLC11A2, PAWR, S100A8, S100A9, SNCA, TRAF2, TRADD, RIPK1, CRADD, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR, AIFM1, EIF2AK3, TNFSF15, CASP8AP2, PDCD6, BCL2L10, BCL2L11 |
1475 | GO:0032845 | 0.00 | 2.73 | 37.94 | 60 | 91 | negative regulation of homeostatic process | ADA, ADORA1, ANPEP, ATM, ATP1A2, AVPR2, BAX, CD38, CD74, CCR5, COMT, CYBA, DIAPH1, TSC22D3, EDNRA, ERCC1, ERCC4, F2R, FCER1G, XCR1, HMGCR, HRC, HTR2C, IAPP, IL13, ITPKB, ITPR1, ITPR2, ITPR3, KITLG, TNFRSF11B, P2RX7, PDE4D, PDPK1, PLN, PRKACA, PRKCE, PRKD1, PTPN6, RYR1, RYR2, RYR3, CCL21, XCL1, SLC8A1, SNCA, STAT5B, TNFAIP3, TRPC1, TRPV1, TNKS, BCL10, HAP1, AKAP6, ATG5, CARTPT, RAD50, CHERP, GAS2L1, CORO1A |
1476 | GO:0007420 | 0.00 | 2.73 | 52.31 | 83 | 127 | brain development | ACAT1, ACTB, AK2, AK4, SHROOM2, ARF4, ATM, ATP2B1, ATP5F1, ATP5J, BID, BMPR2, BOK, BRCA1, BRCA2, BYSL, CALM3, CASP5, CD9, CDC42, CENPF, CLN5, COX6B1, CTNS, CTNND1, DNMT1, S1PR1, CELSR2, EML1, EPHA7, ACSL3, FGF9, AFF2, GLUD1, H3F3B, HMGCS1, HMGCS2, HMX2, IGF1R, KCNK3, LDHA, MEN1, CITED1, NTF3, OXCT1, PAFAH1B2, PAFAH1B3, PPT1, PTCH1, RAD1, QARS, S100A1, SEPP1, SLC6A11, SMARCA1, STAR, STXBP3, SYT1, SYT4, TULP3, UBE3A, WNT2, WRN, YWHAH, ZIC1, ZIC2, ZNF148, ITGA8, UNC5C, DYNLL1, ATP6V0D1, INA, SYNGR3, BAG3, AATK, SNPH, BCL2L11, ABCB6, COX17, TSPAN2, RAPGEF3, SLC38A3, VAX1 |
1477 | GO:0031347 | 0.00 | 2.73 | 114.93 | 181 | 278 | regulation of defense response | ADAR, AP2A1, AP2B1, AP1G1, ANXA5, ARF1, BTK, CA7, CALM3, CASP8, CD4, CD14, CD86, CD36, CD37, CHUK, AP2M1, AP1S1, AP2S1, COX8A, CPA3, CLDN7, ATF2, CTSK, CYBA, CYLD, COCH, DMBT1, DUSP4, DUSP7, EIF2S1, ELK1, EP300, STOM, EREG, F2RL1, FCGR3B, FCN1, FGF7, FGR, FYN, SLC37A4, GFI1, UBE2K, HPX, HSP90AB1, ICAM2, IFI16, IFIT1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNGR1, IGF2, IRAK1, IRAK2, IRF1, ITGAM, ITPR1, ITPR2, ITPR3, JUN, KCNQ1, KRAS, LTF, MDH1, NRAS, NTHL1, PDK4, PDPK1, PENK, PGC, SERPINB9, SERPINB10, PIK3C3, PPM1B, PPP2R5D, PPP3R1, PRKACA, PRKACB, PRKACG, PRKCE, MAPK3, MAPK8, EIF2AK2, KLK7, PSMA1, PSMA2, PSMA4, PSMA5, PSMA7, PSMB1, PSMB2, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN1, PTPN6, PVR, RAC1, RAF1, RELB, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SERPINB4, SCN1A, SEC14L1, SKP1, SNRPD1, STAT2, SYK, TARBP2, TYK2, UBB, UBE2D1, UBE2D2, UBE2V1, SUMO1, UCN, NR1H2, VAV1, ZNF189, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, CUL1, IKBKG, RIPK1, RIPK2, AP1S2, AP1M1, BCL10, HIST1H3F, UBA3, RPS6KA5, CHST3, PSMF1, NR1D1, NUP93, PUM1, PHYHIP, IST1, ELMO1, PSMD6, TRIL, NR1H4, FGFBP1, AP1M2, PSME3, TRIM38, CREB3, CSPG5, CNPY3, TRAF3IP2, MALT1, TRAFD1, SPINK5, CDC37, USP18 |
1478 | GO:0006090 | 0.00 | 2.73 | 22.12 | 35 | 53 | pyruvate metabolic process | AGXT, ALDOB, ALDOC, ARNT, BPGM, BSG, DLD, ENO2, GAPDH, GPD1, HIF1A, HK2, IGF1, INS, LDHA, LDHC, OGDH, P2RX7, PCK1, PDK4, PFKFB2, PFKFB4, PGAM2, PGK1, PGK2, PGM1, PPP2R5D, PRKAA1, SLC16A1, STAT3, PDHX, OGT, HDAC4, SDS, ECD |
1479 | GO:0044707 | 0.00 | 2.73 | 54.61 | 93 | 162 | single-multicellular organism process | A2M, ACTN4, SERPINC1, BRS3, CAPZA1, CAPZB, ENTPD1, ENTPD2, CD48, CD59, COL4A6, COL16A1, COL17A1, CSRP1, CTSD, CTSS, DGKA, DGKB, DGKQ, EPS8, F10, G6PC, GGCX, GNA15, GNAI1, GNAI3, GRB7, GSTM2, GUCY1B3, HBD, HBG1, HBG2, SERPIND1, IRF2, ITGAL, ITGAM, KLC1, KRT14, KRT33B, KRT83, LAMP2, LMAN1, OLR1, SERPINA5, PEPD, PF4V1, PTPN1, RAB27A, RAP2B, RBM4, SELE, SELL, SELPLG, SEMG1, SLC16A1, SNCA, SNRPE, TARBP2, HNF1A, TNNC2, TNNI2, TRH, TUBA4A, VAV1, XPA, YWHAZ, SMC1A, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, DGKE, SNAP23, PROZ, HIST1H3F, DOK2, SMC3, FIBP, SLC22A6, GNA14, TRAM2, RASGRP2, ABCC4, SH2B2, STAG2, PDE10A, RAPGEF4, ADAMTS13, KIF3A, SLC7A9, AKAP10, HPS5 |
1480 | GO:0006094 | 0.00 | 2.72 | 19.60 | 31 | 47 | gluconeogenesis | ALDOB, ALDOC, ATF3, ATF4, BPGM, CRY1, SLC25A10, ENO2, G6PC, GAPDH, GOT1, GOT2, GPD1, GPD2, INS, MDH1, MDH2, PCK1, PCK2, PGAM2, PGK1, PGM1, PRKACA, PRKACB, PRKACG, RANBP2, SLC25A1, OGT, SLC25A13, ARPP19, SDS |
1481 | GO:0090263 | 0.00 | 2.72 | 34.22 | 54 | 82 | positive regulation of canonical Wnt signaling pathway | APC, XIAP, ARNTL, COL1A1, CSNK1D, CSNK1G2, DLX5, EDA, FGF9, FGFR3, RBPJ, ILK, JUP, SMAD3, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SFRP4, SOX4, UBB, WNT1, WNT2, WNT2B, FZD5, TNKS, PSMF1, USP34, PSMD6, FRAT1, PSME3 |
1482 | GO:0009314 | 0.00 | 2.72 | 30.87 | 49 | 75 | response to radiation | ALAD, ANGPT2, ANXA1, ATM, BCL2L1, BRCA1, COL3A1, CRYAB, CYBA, GADD45A, DNMT1, DNMT3A, DNMT3B, ECT2, EYA1, EYA3, FANCD2, FANCG, GATA3, GRB2, ICAM1, IFI16, IGF2, IL1B, IL1R1, JUN, KRT13, KRT14, MGMT, NTRK1, PENK, PGM1, RAD1, RAD51, RAD51B, RAD51D, RRM1, SNAI2, STAR, XRCC2, XRCC4, SMC1A, PPM1D, MBD4, SOCS3, RNF8, BRE, RAD51AP1, CHEK2 |
1483 | GO:0042307 | 0.00 | 2.72 | 18.35 | 29 | 44 | positive regulation of protein import into nucleus | BRCA1, CDH1, ECT2, EDA, FLNA, HCLS1, HSP90AB1, IGF1, IL1B, IL18, JUP, KPNA1, IPO5, SMAD3, PPP3R1, PRKCQ, SHH, SLC9A1, TRIP6, ZIC1, TNFSF14, IL18R1, HDAC3, AKAP6, TRIM28, NUTF2, CHERP, RBCK1, EDAR |
1484 | GO:0043086 | 0.00 | 2.71 | 25.76 | 41 | 63 | negative regulation of catalytic activity | ANXA2, ANXA3, ANXA4, ANXA5, APOC2, CALU, CNR1, CNR2, CYP27B1, EDNRB, ENSA, GALR1, GFI1, GNAI3, HP, IL13, INS, CD46, PPP1R12A, OAZ1, OAZ2, PDC, PDE6G, PDE6H, PPP1R2, PPP1R8, PTN, ABCE1, SAG, SET, SLN, SNCB, SCGB1A1, CABP1, APBA3, GABBR2, PHACTR2, HDAC6, FRY, TXNIP, ARPP19 |
1485 | GO:0010976 | 0.00 | 2.71 | 45.07 | 71 | 108 | positive regulation of neuron projection development | ABL2, APBB1, ARF1, BMP4, BMPR2, CNR1, CUX1, DPYSL3, LPAR1, EFNA5, EPHA3, EPHA4, FYN, GOLGA4, RAPGEF1, GRN, ARHGAP35, HGF, NRG1, ILK, ITGA3, ITGB1, LIMK1, CAPRIN1, NTRK1, NTRK2, NTRK3, OPA1, P2RY2, PARK2, PCP4, SERPINF1, PRKCI, PRKD1, RELN, PTK7, PTN, PTPRD, PTPRZ1, RAP1A, SGK1, SRF, CDKL5, STK11, SYT1, SYT4, VEGFA, LRP8, RND2, SF3A2, SEMA7A, CAMK1, RAB11A, KAT2B, CBFA2T2, NUMBL, SLIT2, CPNE6, ADAMTS1, RAPGEF2, RIMS2, IST1, CUL7, FIG4, KATNB1, BAIAP2, STK25, AVIL, STMN2, IL1RAPL1, TWF2 |
1486 | GO:0071407 | 0.00 | 2.71 | 42.24 | 67 | 103 | cellular response to organic cyclic compound | ABCA1, ADAR, ADCY1, ADCY3, ADCY6, AKT2, APLP1, BAD, BYSL, CASP8, CASQ2, CCNB1, CDC5L, COL1A1, CYBA, DIAPH1, DNM2, FGA, GABRB2, GNAI1, GNAS, GNB1, GPLD1, GSTM2, HIF1A, HMGCS1, HRH1, HSP90AB1, IFIT1, IL1B, IL18, KCNJ11, SMAD1, SMAD3, MGMT, NTRK1, P2RX4, P2RX7, P2RY1, P2RY2, P2RY6, P2RY11, PARK2, PDE4B, PRKACA, PTCH1, RAD51, RBM3, RYR1, RYR2, RYR3, SHMT1, SLC9A1, SLC16A1, SLC34A1, SNCA, SOD1, STAT3, TARBP2, TMF1, TRPV1, LRP8, PRKRA, KLF4, KLF2, CIB2, CHEK2 |
1487 | GO:1902107 | 0.00 | 2.71 | 31.72 | 50 | 76 | positive regulation of leukocyte differentiation | ADA, ANXA1, ATP6AP1, AXL, BAD, PRDM1, BTK, CA2, CASP8, CD80, CD86, CD74, CCR1, EGR3, FLT3LG, GAS6, GATA3, GNAS, HCLS1, HLX, IFNG, IHH, IL1B, IL2RA, ITPKB, JUN, CD46, KITLG, PF4, PRKCA, PRKCZ, RAG1, RARA, RB1, SHH, STAT5B, SYK, KLF10, TNFSF4, OGT, AP3B1, TNFSF11, RIPK1, TNFSF9, RIPK2, IL1RL2, VNN1, AP3D1, TRIB1, IKZF1 |
1488 | GO:0051289 | 0.00 | 2.70 | 17.11 | 27 | 41 | protein homotetramerization | ACADL, ACADS, CAT, CDA, CRYZ, CTH, DECR1, DHPS, GLS, GOLGA2, GPX3, HSD17B10, HPRT1, IDE, IMPDH2, KCNJ2, KCNJ12, PEX14, PEX5, RXRA, RXRG, RYR3, SHMT1, SHMT2, SOD2, TP63, USP16 |
1489 | GO:0006816 | 0.01 | 2.70 | 11.99 | 19 | 29 | calcium ion transport | ADRB2, ANXA6, CAMK2G, CHRNB2, CLCA1, CYP27B1, FYN, GJA4, ICAM1, IGF1, KCNN4, PRKCB, RCVRN, TPT1, VDR, CD84, CALCRL, RAMP2, RAMP3 |
1490 | GO:0002521 | 0.00 | 2.70 | 40.48 | 64 | 98 | leukocyte differentiation | ABL2, RHOH, ATM, BAX, BCL2, BCL3, BMX, ZFP36L2, RUNX2, CBFB, CD2, CD3D, CD4, CD8A, CD28, TNFSF8, CDK6, CEBPG, CR2, GPR183, EP300, FCER1G, ONECUT1, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IL10, ITGA4, ITGB1, NTRK1, PAX1, PTGER4, PTPN6, RAG2, RPL22, RRAS, SATB1, SOD1, SOS1, SOS2, SOX4, SPN, SRF, STK11, TPD52, TSC1, TYRO3, WNT1, FZD5, EOMES, FZD7, FZD8, FZD9, FOXN1, IL18R1, SOX13, VPRBP, HDAC4, RNF41, MALT1, SPINK5, TUSC2 |
1491 | GO:0008203 | 0.00 | 2.70 | 14.55 | 23 | 35 | cholesterol metabolic process | ABCA1, ACADL, ACADVL, APOF, APLP2, CAT, SCARB1, CETP, CYP11B1, FDXR, FECH, LCAT, LIPE, RXRA, SORL1, STAR, TNFSF4, CUBN, NR0B2, SOAT2, CH25H, SNX17, NR1H4 |
1492 | GO:0032946 | 0.00 | 2.70 | 30.46 | 48 | 73 | positive regulation of mononuclear cell proliferation | ADA, ADK, ANXA1, BCL2, CD4, CD6, CD28, CD80, CD86, CD38, CD40, CD59, CD74, CDKN1A, CHRNB2, CD55, DHPS, GPR183, HES1, IFNG, IGF1, IGF2, IGFBP2, IL1B, IL2RA, IL13, IL18, ITGAL, CD46, PRKCQ, XCL1, SHH, ST6GAL1, SPN, SPTA1, STAT5B, SYK, TAC1, TNFSF4, TNFRSF4, ZP3, TNFSF9, RIPK2, EBI3, VAV3, TNFSF13B, HHLA2, CORO1A |
1493 | GO:0001890 | 0.00 | 2.70 | 14.56 | 23 | 35 | placenta development | ADA, ANG, BMPR2, BSG, CTSV, CYP27B1, DCN, DLX3, ESR1, ETV2, GHSR, GJB2, HSP90AB1, MEN1, SERPINE1, PTGIS, RXRA, SOD1, STC1, VDR, FOSL1, CUL7, PRDX3 |
1494 | GO:0090596 | 0.00 | 2.70 | 25.33 | 40 | 61 | sensory organ morphogenesis | ATOH1, ATP2B2, ATP6V1B1, COL2A1, COL11A1, DLX5, DLX6, EPHB2, EYA1, FGF3, FGF8, FGF9, GATA3, GFI1, HMX2, HPN, INSIG1, KRT13, OTX1, PRRX1, MAPK3, PTK7, RAC1, RPL38, SALL1, SIX1, SOD1, CLRN1, WNT1, ZIC1, PAX8, FZD3, FZD6, ITGA8, PRKRA, HESX1, SLC9A3R1, SEC24B, SIX2, GJB6 |
1495 | GO:0045787 | 0.01 | 2.70 | 10.73 | 17 | 26 | positive regulation of cell cycle | CCNC, CCND3, CCNH, CCNT1, CCNT2, OVOL1, PGGT1B, PIM1, RARA, STIL, SLC6A4, SRPK2, NR2E1, FOSL1, CCPG1, BCL2L11, CITED2 |
1496 | GO:0009112 | 0.00 | 2.70 | 15.86 | 25 | 38 | nucleobase metabolic process | ADA, ADK, ADSL, ADSS, AMPD1, AMPD2, AOX1, APRT, CAT, CDA, CPS1, DHODH, DPYD, DUT, TYMP, GPX1, HPRT1, IL1B, IMPDH1, IMPDH2, ALDH6A1, RRM1, SHMT1, TYMS, UPP1 |
1497 | GO:0006921 | 0.00 | 2.69 | 14.61 | 23 | 35 | cellular component disassembly involved in execution phase of apoptosis | ADD1, APC, BAX, BMX, CASP6, CASP8, CDH1, CDKN2A, DFFA, DFFB, DNASE1L3, DSP, FNTA, GAS2, KPNA1, KPNB1, PRKCQ, SATB1, TOP2A, VIM, AIFM1, ERN2, CAPN10 |
1498 | GO:0006952 | 0.00 | 2.68 | 29.79 | 48 | 76 | defense response | ANXA3, KLK3, BCL3, BNIP3, BNIP3L, BPI, CACNA1E, CAMLG, CCK, CD8A, TNFSF8, CD48, CD74, CEBPE, CTSG, CXADR, DBI, DPP4, EIF4E, EIF4G1, HRG, HTR2C, IFNW1, KCNJ8, KCNN4, P2RY11, PRG2, DNAJC3, PSG3, RAB1A, RNASE6, SEMG1, NR2E1, TMF1, TPSAB1, EPX, FOXN1, IL32, SOCS6, IL27RA, ADAMTS4, ABCC9, DEAF1, ATG7, BATF, IFI44L, ADAMTS5, SP140 |
1499 | GO:1901292 | 0.00 | 2.68 | 25.46 | 40 | 61 | nucleoside phosphate catabolic process | ADA, ARNT, CAT, ENTPD2, CNP, DUT, GPD1, GPX1, HIF1A, HPRT1, IGF1, INS, NUDT1, NTHL1, OGG1, P2RX7, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, ENPP1, ENPP3, PRKAA1, STAT3, UNG, UPP1, OGT, PDE5A, MBD4, ENTPD4, HDAC4, RAPGEF3, PDE10A, NUDT3, ECD |
1500 | GO:0030217 | 0.01 | 2.68 | 10.77 | 17 | 26 | T cell differentiation | ABL2, RHOH, BMX, RUNX2, CD2, CD4, CD8A, TNFSF8, FLT3, KIT, PAX1, RPL22, SATB1, SOX4, SP3, SOX13, SPINK5 |
1501 | GO:0009187 | 0.00 | 2.68 | 21.59 | 34 | 52 | cyclic nucleotide metabolic process | ADCY1, ADCY3, ADCY6, ADCY9, AMPD2, APLP1, AQP1, ATP2B2, CACNB4, CNP, LPAR1, EDNRB, GALR1, GNAI3, GRM8, GUCY1B3, GUCY2C, GUCY2F, GUCY2D, HTR2C, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, VEGFA, PDE5A, AKAP6, GABBR2, PDE10A |
1502 | GO:0006301 | 0.01 | 2.67 | 13.35 | 21 | 32 | postreplication repair | BRCA1, DDB1, REV3L, RFC1, RFC2, RFC3, RFC4, RFC5, RPA3, RPS27A, UBB, UBA7, UBE2V1, UBE2V2, UFD1L, TRIM25, CUL4B, CUL4A, KIAA0101, RBX1, MAD2L2 |
1503 | GO:0060425 | 0.01 | 2.67 | 13.35 | 21 | 32 | lung morphogenesis | BMP4, CDC42, CTSZ, FGF7, FGF8, GATA4, HHEX, FOXA2, TNC, IGF1, KRAS, MAPK3, SRSF6, SHH, SOX2, SOX9, SOX11, SRF, WNT2, WNT2B, SEC24B |
1504 | GO:0071479 | 0.01 | 2.67 | 13.35 | 21 | 32 | cellular response to ionizing radiation | ATM, ATR, BCL2L1, CDKN1A, CRYAB, CYBA, GADD45A, DNM2, ECT2, ELK1, GATA3, GRB2, IFI16, ITGB1, MGMT, RAD1, RAD51, SNAI2, WRN, CLOCK, RAD51AP1 |
1505 | GO:0015850 | 0.00 | 2.67 | 31.16 | 49 | 75 | organic hydroxy compound transport | ABAT, ADRA2C, ADRBK1, AGTR2, AQP1, AQP5, AQP6, AQP7, BMP6, SLC25A20, CHRNB2, CNR1, CPT1B, CPT2, FCER1A, FCER1G, GALR1, GDNF, GPM6B, FFAR3, KCNA2, OXT, P2RY1, PARK2, PCP4, PRKAB2, PTGS1, RAB3B, SEC14L1, SLC5A3, SLC6A2, SLC6A4, SLC16A1, SLC18A1, SLC22A1, SLC22A3, SLC22A2, SLC22A5, SNCA, SYK, TAC1, TMF1, CADPS, SLC16A6, SLC16A5, SLC16A4, SLC16A7, CARTPT, HRH3 |
1506 | GO:0040011 | 0.00 | 2.67 | 260.59 | 404 | 643 | locomotion | ABL2, ACTB, ACTG1, ADCY3, AP2A1, AP2B1, ANG, ANXA1, ANXA5, APOA1, SHROOM2, ARF4, ASTN1, RERE, ATOH1, ATP1A2, ATP1B3, ATP2B2, BAX, BBS2, BBS4, DST, BSG, BTG1, TSPO, CACNA1E, CACNA1S, CACNB4, CALM3, CAMK2A, CAMK2G, CCK, CD2, CD44, CD48, CD58, CD72, CD151, CDC42, CDK5, CDK6, CHN1, CHRM1, AP2M1, AP2S1, CLTA, CCR3, CCR8, ACKR2, COL2A1, COL4A3, COL4A4, COL4A5, COL5A1, COL5A2, COL6A2, COL6A3, COL9A1, COL9A3, CSF2, CSF2RB, CSNK2A1, CSNK2A2, VCAN, CSPG4, CTGF, CTNNA2, DBH, DCC, ACE, DCX, DEFA1, DLG1, DLG3, DLX5, DNM1, DNAH5, DNAH8, DUSP5, DUSP7, DUSP9, TYMP, ECM1, EDNRB, EFNA1, EFNA3, EFNA4, EFNA5, CELSR2, EGR2, EGR3, EPHA2, EMP2, CTTN, EMX2, ENPEP, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPS8, ERBB2, EREG, ERG, ETV1, ETV4, EXT1, FAP, EFEMP1, FCER1G, FGF3, FGF6, FGF8, FGF9, FGFR3, FGFR4, FPR1, FPR2, FPR3, FUT8, FYN, GAP43, GAS8, GDNF, GFRA1, B4GALT1, GPC1, GPM6A, CCR10, XCR1, GPR15, GPX1, GRB2, GRIN2A, ARHGAP35, HIST1H1T, SERPIND1, HCK, HEXB, NR4A1, HRH1, HES1, HSPA8, HSP90AA1, HSP90AB1, IL2RA, IL2RB, IL2RG, IL10, ING2, ITGA6, ISL1, ITGA1, ITGA7, ITGA9, ITGAL, ITGAM, ITGAX, ITGB4, JUP, KIF5A, KRAS, KRT2, LAMA3, LAMA4, LAMA5, LDHC, ABLIM1, LIMK1, LSP1, MARK3, SMCP, NRAS, NRCAM, NRTN, NTRK1, NTRK2, NTN3, OGDH, OLR1, OPHN1, OR1D2, OTX2, P2RY1, PEBP1, PCM1, PDE4B, PDE4D, PDPK1, PGK2, PIK3C2A, PIK3C2B, PIK3CB, PIK3CG, PPP5C, PRCP, PRKCI, PRKCQ, PRKCZ, PRKG1, MAPK3, PRKX, PSPN, PROC, PROS1, PSG2, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTK7, PTPN6, PTPRA, RAB1A, RAB13, RAF1, RALA, RASA2, RFX3, RNASE2, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS19, RPS27A, RYK, S100A2, S100A8, S100A9, S100A12, S100P, SAA4, SCN5A, SCNN1B, CCL22, SDC1, SDC2, SDC4, SELL, SFTPD, SGK1, ITSN1, SHC1, SIAH1, SIAH2, SIX1, SIX3, SLC9A1, SLC16A1, SLIT1, SLIT3, SNCA, SORD, SORL1, SOS1, SOS2, SOX1, SOX10, SPN, SPTA1, SPTB, SRMS, STAT5B, CDKL5, STK10, XCL2, SYK, T, CNTN2, NR2F1, NR2E1, TMF1, TNP2, TNR, TNS1, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TSC2, TYK2, TYROBP, UBB, CLRN1, VAV1, EZR, LRP8, FZD3, ARHGEF5, FOSL1, CUL5, FGF23, SLC7A5, USP9X, USP9Y, EPX, FZD4, SOX14, CUL3, FOXN1, SORBS2, CDC42BPA, CNTNAP1, TNFSF11, KLF7, DNAH17, UNC5C, DCHS1, PEA15, DNAH11, TNFSF12, CD84, AKAP4, SGPL1, PHOX2B, CDK5R2, RPS6KA4, KALRN, DOK2, PSTPIP2, PSTPIP1, USP14, DCLK1, RPS6KA5, TAOK2, CER1, NRXN3, NRXN1, HAND2, PSMF1, CDC42BPB, FEZ2, SDC3, SLK, ZEB2, ELMO1, GAB2, FARP2, KIAA0319, PSMD6, RBX1, RANBP9, GPC6, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN1, ARPC2, AKAP9, ABI2, RASA4, WASF2, TNK2, PSME3, RCAN2, APC2, SPON2, VAV3, CAP2, CAP1, PROCR, ARPC1A, DPYSL4, PDPN, CXCR6, TBR1, SIX2, CHL1, GIPC1, CCR9, FRS3, VAX1, SLC7A9, PTGDR2 |
1507 | GO:0051241 | 0.00 | 2.67 | 103.18 | 162 | 252 | negative regulation of multicellular organismal process | ABAT, ACVRL1, ADA, ADCY6, AGTR2, ALOX12, ANPEP, ANXA2, ANXA5, APC, APOC2, ARF6, ARHGAP4, ARHGDIB, ASCL2, AVP, AVPR2, BMPR1A, BMPR2, SERPING1, CD86, CD38, CD63, CDK5, CHAD, CNTF, COL3A1, COMT, CRP, CRY1, CTNNA1, CYBA, DCC, DDX6, DPYSL3, LPAR1, EDNRB, EFNA1, EIF4E, EPHA4, EPHA7, F2R, F12, FAP, FGA, FGFR3, FGG, NR5A1, GAK, GDI1, GFAP, GFI1, GJA5, GLRA1, GP1BA, NRG1, HMGCR, FOXA2, HPN, IAPP, IGF1, IL1B, INS, ISL1, ITGB1, KLKB1, KNG1, KRT1, LRPAP1, TACSTD2, SMAD7, CIITA, NTRK3, TNFRSF11B, OXT, P2RX4, P2RX7, REG3A, PAX2, PBX1, PCM1, PDE4B, PDE4D, PFN2, PLN, PROC, PROS1, PTPRR, PTPRZ1, RAP1A, RAP1GAP, REST, RFX4, RNF6, RPS19, SALL1, SEMA3F, SFRP5, SRSF6, SIX1, SIX3, SLC6A4, SLIT1, SORL1, SOX3, SOX11, SP100, SRF, STAT3, STC1, STK11, TAC1, TACR2, CNTN2, DYNLT1, NR2F2, NR2E1, TNR, TTC3, UCN, USF1, VIM, VTN, YWHAH, PAX8, SEMA3B, AKAP1, TP63, PHOX2B, RGN, CBFA2T2, ARHGEF2, SLIT2, EIF2AK3, BAG5, AATK, PHF14, RAPGEF2, ZNF536, KIAA0319, FIG4, RNF10, OLIG2, HMG20A, SEMA3A, RAPGEF3, OLFM1, MAD2L2, CARM1, SEMA6C, SEMA6B, SEMA4F, SEMA4B, PROCR, PRDX4, CXCL13, NRG3, VAX1, STMN2, CIT, STRAP, PTGDR2 |
1508 | GO:0071456 | 0.00 | 2.67 | 22.91 | 36 | 55 | cellular response to hypoxia | ADRB2, AQP1, BAD, BCL2, BDKRB2, BNIP3, BNIP3L, CCNB1, CLCA1, DNMT3A, EIF4EBP1, SLC29A1, GATA6, GNB1, GNGT1, ICAM1, IRAK1, KCND2, KCNK2, KCNK3, PRKAA1, PRKCE, PTGIS, PTN, S100B, SLC2A4, SLC8A1, SLC8A3, SLC9A1, STC1, SUV39H1, TRPC1, TWIST1, OGT, ACAA2, USP19 |
1509 | GO:0051146 | 0.00 | 2.67 | 32.50 | 51 | 78 | striated muscle cell differentiation | ACTG1, ACVR1, AGTR2, BCL9, CACNA1S, CACNB4, CASQ2, CAV2, CCNB1, CFL2, CHUK, CXADR, FLNC, GATA4, GATA6, KAT2A, GPX1, IGF1, IGF2, IGFBP5, ITGB1, KRAS, KRT19, PRKAR1A, RARA, RARB, RB1, RXRA, RYR1, SORT1, SDC1, SGCB, SLC8A1, SLC9A1, SRF, TMOD1, TNNT2, TSC1, VEGFA, WNT1, XK, CSRP3, IFT88, SORBS2, DYRK1B, ATG5, WDR1, SPEG, ATG7, PDLIM5, BVES |
1510 | GO:0043207 | 0.00 | 2.66 | 202.82 | 313 | 486 | response to external biotic stimulus | ABCA1, ACP5, ACTA2, ADAR, ADARB1, ADH5, AP2A1, AP2B1, AP1G1, ALAD, ANG, ANXA3, ANXA5, BIRC3, KLK3, ARF1, ARG1, ASS1, ATP4B, AXL, BAD, BCL2, BCL2L1, BCL3, PRDM1, BMP6, BNIP3, BNIP3L, BPI, BST2, BYSL, TSPO, C1QBP, CA7, CASP8, CASP9, CD4, CD6, CD8A, CD14, CD28, CD80, CD86, TNFRSF8, TNFSF8, CD36, SCARB1, CD37, ENTPD2, CD40, CDK6, CEBPE, CHUK, AP2M1, AP1S1, AP2S1, CLU, CCR5, CNP, CNR1, CNR2, COMT, COX8A, CPA3, CLDN7, CPS1, CRP, CSF2, CTSG, CX3CR1, CXADR, CYBA, CYP1A2, CYP27B1, CD55, DCN, DDX1, DDX3X, DEFA1, COCH, DMBT1, DNMT1, EDNRA, EDNRB, EIF2S1, STOM, F2R, F2RL1, F3, FAU, FCER1G, FCGR3B, FCN2, FGA, FGF7, FGR, FYN, SLC37A4, GATA3, GFI1, GPX1, CXCL1, CXCL2, CXCL3, GTF2F1, HCK, HIF1A, HMGCS2, HMGA1, HP, HRG, HSPB1, ICAM1, IFI16, IFIT1, IFIT3, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNGR1, IFNW1, IGF1, RBPJ, IL1B, IL2RA, IL10, IL10RA, IL12RB2, IL13, TNFRSF9, IL18, IDO1, IRAK1, IRAK2, IRF1, IRF5, ISG20, JUN, JUNB, JUND, KCNJ8, KCNQ1, LTF, CD180, SMAD3, MDH1, MGST2, CITED1, NRF1, NTHL1, OAS1, OAS2, OAS3, ODC1, TNFRSF11B, P2RX7, P2RY2, SERPINE1, PAWR, PDE4B, PDE4D, PDK4, PENK, PF4, PF4V1, CFP, PGC, SERPINB9, SERPINB10, PPM1B, PRG2, PRKCA, PRKCE, MAPK3, MAPK8, EIF2AK2, DNAJC3, PROS1, KLK7, PSMA2, PTAFR, PTGER1, PTGER4, RAB1A, RAC1, RARA, RNASE3, ABCE1, RPL39, RPS6KA3, S100A8, S100A9, S100A12, SCN1A, CCL20, CCL22, CXCL6, CXCL5, XCL1, SEC14L1, SELE, SELP, SEMG1, SFTPD, SLC11A1, SLPI, SNCA, SNRPD1, SPARC, SPN, STAR, STAT2, STAT5B, ABCC8, SYK, TAC1, TARBP2, TMF1, TNFAIP3, TNFRSF1A, TNFRSF1B, TPT1, TNFSF4, TNFRSF4, SCGB1A1, VIL1, VIP, TRIM25, ZNF189, FZD5, FOSL1, CHAF1B, EPX, HIST1H2BG, HIST1H2BF, HIST2H2BE, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, OGT, PPM1D, PARG, IKBKG, FCN3, PRKRA, OASL, BECN1, URI1, ADAM9, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, BANF1, AP1S2, AP1M1, BCL10, HIST1H3F, HIST1H2BJ, PGLYRP1, SOCS3, DDX21, DCLK1, IL27RA, CHST3, ATG5, ADAMTS4, LITAF, NR1D1, NUP93, PUM1, PHYHIP, IST1, ELMO1, NR1H4, FGFBP1, BCL2L11, AP1M2, ABCC9, IL18BP, TRIB1, TRIM22, IFITM3, SPON2, BAIAP2, TRIM38, CREB3, ATG7, BATF, CXCL13, GNLY, IFITM2, IVNS1ABP, CSPG5, TRAF3IP2, GJB6, MALT1, PRDX3, SERINC3, IFI44L, SPINK5, IL24, PIM2, ADAMTS5, CD160, TUSC2 |
1511 | GO:0001525 | 0.00 | 2.66 | 49.70 | 78 | 120 | angiogenesis | AAMP, ACVR1, ANG, ANGPT1, ANPEP, ANXA2, BAX, BMP4, KLF5, CASP8, CDC42, CSPG4, CTGF, TYMP, S1PR1, EDNRA, EFNA1, EFNB2, EGR3, EPHA2, ELK3, EMP2, ENPEP, EPHB1, EPHB2, EPHB3, ERBB2, EREG, FAP, FGF6, FGF8, FGF9, FLT4, GJA5, GPLD1, NR4A1, RBPJ, IHH, IL18, ITGAV, ITGB1, JUN, KRT1, LAMA5, MEIS1, MEOX2, MFGE8, NRCAM, ENPP2, PIK3CG, PRKX, PTPRB, SAT1, SHB, SHC1, SHH, SP100, SRPK2, SYK, TAL1, TNFAIP2, VEZF1, FZD5, SCG2, FZD8, ADAM15, NRP2, SLIT2, NRXN3, NRXN1, HAND1, EIF2AK3, HAND2, WASF2, CALCRL, VAV3, CXCL13, ESM1 |
1512 | GO:0060411 | 0.01 | 2.66 | 12.10 | 19 | 29 | cardiac septum morphogenesis | ACVR1, FGF8, GATA4, GATA6, GJA5, HES1, ISL1, SMAD7, PROX1, RARA, RARB, SOX4, SOX11, WHSC1, WNT11, IFT88, DHRS3, HAND1, CITED2 |
1513 | GO:0007169 | 0.00 | 2.66 | 53.63 | 85 | 133 | transmembrane receptor protein tyrosine kinase signaling pathway | ABL2, ADORA1, ADRA2C, ADRB2, ALK, ANGPT2, APLP2, AREG, ARF4, BDKRB2, BLK, BMX, BTK, CAMLG, CD4, CD7, CD8A, CDH3, CSH1, CSPG4, DOK1, EPS8, EPS15, ESR1, F3, F7, EFEMP1, FGR, FRK, GFRA1, GH2, GHRH, GHRHR, GHSR, GRB7, HCK, HGF, IGF1, IGF2R, IGFBP2, IGFBP3, IGFBP5, IGFBP6, INSRR, ITGA1, NRTN, NTF3, NTF4, DDR2, PDE6G, PDE6H, PDGFRL, PIGR, PTPN6, PTPRJ, PTPRR, ATXN7, SNCA, SOX9, SRMS, STAT5B, SYK, TYK2, VIL1, WNT1, RAB7A, STAM, IFT88, TNK1, SGPL1, DOK2, ANGPTL1, REPS2, SLC9A3R1, EIF2AK3, PHF14, RASSF2, GAB2, TNK2, STAM2, AGR2, TXNIP, RGS14, NRG3, ESM1 |
1514 | GO:1904951 | 0.03 | 2.66 | 8.24 | 13 | 20 | positive regulation of establishment of protein localization | BCL2, BID, CASP8, MAPK8, YWHAG, YWHAH, YWHAZ, DYNLL1, BCL2L11, CCT7, CCT4, CCT2, CCT8 |
1515 | GO:0042100 | 0.01 | 2.65 | 10.84 | 17 | 26 | B cell proliferation | AHR, ATM, BAX, PRDM1, CDKN2A, CR2, CTLA4, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IL10, CD180, PAWR, RAG2 |
1516 | GO:1902106 | 0.01 | 2.65 | 10.84 | 17 | 26 | negative regulation of leukocyte differentiation | ANXA1, BMP4, CD74, CDKN2A, CTLA4, CYLD, DTX1, ERBB2, FLT3, HLX, IFNA2, IHH, IRF1, SHH, TNFSF4, PGLYRP1, TNFSF18 |
1517 | GO:2000145 | 0.00 | 2.65 | 162.34 | 251 | 389 | regulation of cell motility | AAMP, ABL2, ACP5, ACTN4, ACVR1, ACVR1B, ACVRL1, ADA, ADAM10, ADARB1, ADORA1, AGTR2, AKT2, ALOX12, ALOX15B, ANGPT1, ANGPT2, ANXA1, ANXA3, ANXA5, APC, APOH, AQP1, ARHGAP4, ARHGAP5, ARHGDIB, BBS2, BBS4, BCL2, BMP4, BMPR2, BST2, C1QBP, C5, KRIT1, SCARB1, CD63, CD74, CDK5, CDK6, CGA, CCR1, CMKLR1, COL1A1, COL3A1, CLDN7, CTNNA1, CX3CR1, DAB2, DCN, ACE, DIAPH1, DPEP1, DPYSL3, HBEGF, ECM1, S1PR1, LPAR1, EDN2, EDN3, EDNRA, EFNA1, EPHA2, EMP2, EPHA1, ETS1, F2R, F2RL1, F3, F7, F10, FBLN1, EFEMP1, FGF1, FGF7, FGR, FLT1, FLT4, GAS6, GATA3, GPLD1, GRB7, CXCL1, CXCL2, CXCL3, HAS1, HAS2, HGF, NRG1, HIF1A, ONECUT1, HRG, HSPB1, ICAM1, IFNG, IGF1, IGF1R, IGFBP3, IGFBP5, IL1B, ILK, INS, INSL3, ITGA2, ITGA3, ITGA4, ITGA5, ITGAV, ITGB1, JUN, KDR, KIT, KRT16, LAMA3, LAMA4, LAMA5, TACSTD2, EPCAM, SMAD3, SMAD7, KITLG, NTF3, NTRK3, DDR2, P2RY2, P2RY6, SERPINE1, PAWR, ENPP2, PDPK1, SERPINF1, PF4, PF4V1, PFN1, PFN2, PRCP, PRKCA, PRKCE, PRKD1, PRKX, PROX1, RELN, PTAFR, PTGER4, PTN, PTPRJ, PTPRM, PTPRR, PTPRZ1, RAC1, RAC2, RAF1, RAP2A, RAP2B, RDX, RRAS, RREB1, SERPINB3, CCL20, CCL21, CCL24, CCL25, CXCL6, CXCL5, XCL1, CX3CL1, SDC4, SDCBP, SELE, SELP, SEMA3F, SEMG1, SGK1, SHH, SLC8A1, SNAI2, SNAI1, SORL1, SOX9, SP100, SPARC, SRF, STAT3, STC1, STK10, TAC1, NR2F2, NR2E1, TRIP6, TWIST1, VCL, VEGFA, VEGFB, VEGFC, VIL1, VTN, WNT11, ZP3, PTP4A1, SEMA3B, MADCAM1, SOX14, RECK, SEMA7A, IKBKAP, UNC5C, CHRD, NUMB, TNFSF14, ADAM15, ADAM9, RAB11A, TNFRSF18, NRP2, ARHGEF7, TNFSF18, RGN, ITGB1BP1, KLF4, SLIT2, SLC9A3R1, ONECUT2, BAG4, CXCL14, BCAR1, RAPGEF2, SEMA3E, SLK, HDAC4, HDAC6, PDCD6, PTPRU, RNF41, TRIB1, CITED2, SEMA3A, ATP8A1, RAPGEF3, OLFM1, CREB3, SEMA6C, SEMA6B, SEMA4F, SEMA4B, CXCL13, SPINT2, NRG3, IL24, ABHD2, CORO1A, STRAP |
1518 | GO:0001932 | 0.00 | 2.65 | 229.98 | 354 | 555 | regulation of protein phosphorylation | ABL2, ACVR1, ACVR1B, ACVR2A, ACVR2B, ACVRL1, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADORA1, ADRA1B, ADRA2C, ADRB2, AKT2, ALK, ANG, ANXA2, APLP2, APOA1, ARR3, ATM, ATP6AP1, AVP, CCND1, BCL2, BMP1, BMP6, BMP8B, BMPR1A, BMPR2, C3, C5, CAMK2A, CAMK2G, CAV2, CCK, CCNC, CCND3, CCNE1, CCNH, CCNT1, CCNT2, CD4, CD80, CD36, CD40, CD44, CD74, CDC6, CDC25C, CDC42, CDK4, CDK5, CDK9, CENPE, CHI3L1, CKS1B, CLU, CCR1, CNTF, CREBL2, CSF2, CSF2RB, CSNK1D, CSPG4, CTF1, CTGF, DAB2, ACE, HBEGF, GPR183, ECT2, LPAR1, EDN3, EDNRA, EDNRB, EFNA1, EFNA5, EPHA2, EMP2, EPHA4, EPHA7, EPHA8, EPHB1, ERBB2, EREG, ERCC6, ERN1, ESR1, F2R, ACSL1, FCER1A, FECH, FGA, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FGG, FGR, FLT1, FLT3, FLT3LG, FLT4, FPR1, FSHR, FYN, GAS6, GCG, GDF9, GRB2, GRIN2A, GRM1, HCLS1, HGF, NRG1, UBE2K, HPX, HRC, HRG, PRMT1, HES1, HSP90AB1, HTR2C, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF2, IL1A, IL2RA, IL2RB, IL2RG, IL13, IL18, INHA, INS, IRAK1, IRAK2, ISL1, ITGA1, ITGA5, ITGB1, ITPKB, KDR, KISS1, KIT, KRAS, LTF, MARK3, MAP3K5, KITLG, MAP3K11, NRAS, NTRK1, NTRK2, DDR2, TNFRSF11B, P2RY1, PEBP1, PDE6G, PDE6H, ENPP2, PFN2, PIK3CB, PIM1, PIK3CG, PRKAA1, PRKAB2, PRKACA, PRKACB, PRKACG, PRKCE, PRKD1, MAPK3, EIF2AK2, PROX1, RELN, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTGER4, PTPRA, PTPRZ1, RAC1, RAC2, RAD51, RAF1, RAP1A, RAP2A, RAP2B, RASA2, RPS3, RPS27A, RRAS, RYK, S100A12, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SDCBP, SHC1, STIL, SLAMF1, SLC11A1, SOD1, SOS1, SOX2, SOX9, SPN, SPTA1, SPTB, STK10, STK11, STYX, XCL2, SYK, TNFRSF1A, TNFRSF1B, TPD52L1, TRAF2, TSC1, TSG101, TNFRSF4, UBB, UCN, UVRAG, VEGFA, VEGFB, VEGFC, VTN, WNT1, WNT11, ZP3, LRP8, FZD5, ARHGEF5, FGF23, CDK2AP1, FZD4, FZD7, FZD8, BCAR3, SEMA7A, IKBKG, IKBKAP, CAMK1, MAPKAPK5, MADD, TNFSF11, PDE5A, PEA15, RIPK1, ADAM9, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10B, TNFRSF10A, IQGAP1, CDK5R2, RPS6KA4, TNFSF18, DIRAS3, CCNE2, ARHGEF2, BMP15, VAPB, CRLF1, RPS6KA5, GPR55, S1PR2, TAOK2, EIF2AK3, PSMF1, GDF15, BAG4, CARTPT, TRAF4, RAPGEF2, SLK, RB1CC1, ZEB2, PSMD6, OXSR1, TNFSF15, RBX1, ABI1, TOM1L1, RAD50, AKAP9, RASA4, ATP6AP2, SORBS3, TNK2, RNF41, PSME3, ABCA7, RAPGEF3, MAD2L2, STK25, ARL6IP5, NRG3, FRS3, MALT1, JTB, COPS8, ERP29, IL24, RBPMS, CDC37, MAP4K5, CHEK2, FZD10, AKAP13, PHB2 |
1519 | GO:2000058 | 0.00 | 2.65 | 30.05 | 47 | 72 | regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process | CAV3, CCNB1, CDC20, CDC27, CDKN2A, CLU, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SKP1, SUMO3, UBB, UBE2D1, UBE3A, WNT1, CUL1, CDC23, CDC16, PSMF1, PSMD6, PSME3, ANAPC10, UBE2C |
1520 | GO:0051196 | 0.01 | 2.64 | 10.85 | 17 | 26 | regulation of coenzyme metabolic process | ARNT, BPGM, DLD, GPD1, HIF1A, IGF1, INS, P2RX7, PDK4, PGAM2, PRKAA1, SNCA, STAT3, PDHX, OGT, HDAC4, ECD |
1521 | GO:0030073 | 0.03 | 2.64 | 8.26 | 13 | 20 | insulin secretion | ACVR2B, ANXA1, CAMK2G, IL1RN, PTPRN, PTPRN2, RAF1, STXBP3, HNF1A, RAB11B, EIF2AK3, RIMS2, CPLX1 |
1522 | GO:0042594 | 0.02 | 2.64 | 9.57 | 15 | 23 | response to starvation | ACADS, ACAT1, ADSL, ALDOB, CPS1, DHODH, GCG, GCGR, GIP, HMGCL, HMGCS2, OXCT1, SSTR2, SSTR3, ZFP36 |
1523 | GO:0045862 | 0.00 | 2.64 | 41.57 | 65 | 100 | positive regulation of proteolysis | ALOX12, BAD, BAX, BID, BOK, C3, CASP8, CASP9, CCK, CD14, CDKN2A, COL4A3, CR1, CTGF, DDX3X, F2R, F3, F12, FBLN1, FGFR4, GPLD1, HIP1, HPN, IFI16, IFNG, IL1B, KLKB1, SMAD3, MAP3K5, SLC11A2, PAWR, PCOLCE, PHB, REST, RPS3, S100A8, S100A9, SERPINB3, SEMG1, SNCA, CNTN2, CLEC3B, TNFRSF1B, TRAF2, PICALM, OGT, TRADD, RIPK1, CRADD, TNFSF10, ADAM9, TNFRSF10B, TNFRSF10A, CFLAR, BCL10, AIFM1, EIF2AK3, IST1, TNFSF15, CASP8AP2, PDCD6, BCL2L10, BCL2L11, ARL6IP5, ADRM1 |
1524 | GO:0018108 | 0.00 | 2.64 | 30.61 | 48 | 74 | peptidyl-tyrosine phosphorylation | ALK, APLP2, AXL, CLK3, DYRK1A, EPHA2, EPHA1, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, ERBB2, F2R, EFEMP1, FGFR4, FLT1, FLT4, HRG, IL12RB2, INSRR, MAP3K11, NTRK1, NTRK2, NTRK3, DDR2, PPP2R1A, PRKCA, PRKCE, PRKCZ, EIF2AK2, PTK7, PTPN6, RAP2B, RYK, SHC1, SPINK1, TYRO3, WEE1, DYRK2, STK16, DYRK4, BAZ1B, DYRK1B, ABI2 |
1525 | GO:0006140 | 0.00 | 2.64 | 35.84 | 56 | 86 | regulation of nucleotide metabolic process | ABCA1, ADCY7, ADCYAP1R1, ADORA2A, ADRB2, APLP1, AVP, AVPR2, BPGM, TSPO, CALCR, CALM3, CDA, LPAR1, EDNRA, EDNRB, FSHR, GALR1, GCG, GHRH, GHRHR, GLP1R, GNAI3, GNAL, GNAS, GRM8, GUCA1A, GUCA1B, GUCA2A, GUCA2B, INSL3, NTRK1, NTRK2, P2RY11, PDE4D, PF4, PGAM2, PRKCA, PTGER4, PTHLH, RAF1, RCVRN, SNCA, UCN, VEGFA, VIP, VIPR2, WFS1, PDE5A, AKAP6, GABBR2, GUCA1C, CALCRL, RAMP2, CAP2, CAP1 |
1526 | GO:0060070 | 0.00 | 2.64 | 16.58 | 26 | 40 | canonical Wnt signaling pathway | CCND1, BCL9, CDC42, CDH3, CTNND2, EMD, FGF8, GATA3, GATA4, PPP1CA, PTK7, RYK, RYR2, SDC1, STK11, T, TBL1X, KDM6A, FZD3, FZD4, FZD7, FZD8, FZD9, KLF4, PTPRU, FZD10 |
1527 | GO:0016337 | 0.00 | 2.64 | 22.81 | 36 | 56 | single organismal cell-cell adhesion | ACTB, ACTG1, CDH3, CDH7, CDH9, CDH10, COL19A1, CSRP1, CTNNA2, CTNND1, CTNND2, FLNA, GAS6, GNAS, RAPGEF1, HSPB1, ICAM2, ICAM4, ILK, PIK3CB, RAP2B, SHC1, SIGLEC1, SOX9, STXBP1, STXBP3, ICAM5, CRISP2, TYRO3, COL14A1, ZAN, ITGA8, FIBP, SLIT2, PTPRU, PDPN |
1528 | GO:0051279 | 0.02 | 2.63 | 9.58 | 15 | 23 | regulation of release of sequestered calcium ion into cytosol | ATP1A2, CASQ2, CYBA, DIAPH1, HRC, PDE4D, PLN, PRKACA, PRKCE, PRKD1, PTPN6, RYR2, SLC8A1, ATG5, CORO1A |
1529 | GO:0009127 | 0.00 | 2.63 | 19.20 | 30 | 46 | purine nucleoside monophosphate biosynthetic process | ADA, ADK, ADSL, ADSS, AK2, AK4, AMPD1, AMPD2, APRT, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, HPRT1, IMPDH1, IMPDH2, LDHC, PRPS2, STAT3, SURF1, ATP5J2, SLC25A13, ATP5H, ATP5L |
1530 | GO:0015918 | 0.02 | 2.63 | 9.59 | 15 | 23 | sterol transport | ABCA2, APOA1, APOA4, APOC2, TSPO, CD36, SCARB1, CETP, CFTR, CLU, LCAT, OSBP, SHH, STAR, SOAT2 |
1531 | GO:0001656 | 0.02 | 2.63 | 9.59 | 15 | 23 | metanephros development | ACAT1, BCL2, EYA1, FBN1, FGF8, FOXD1, GATA3, GPC3, HOXC11, HOXD11, PTCH1, SHH, SIX1, ITGA8, SLIT2 |
1532 | GO:0048667 | 0.00 | 2.63 | 171.04 | 264 | 412 | cell morphogenesis involved in neuron differentiation | ACTB, ACTG1, ADAM10, ADCY1, AP2A1, AP2B1, ANGPT1, APBB1, APC, ARHGAP4, ATOH1, ATP2B2, BCL2, BMPR2, CACNA1S, CACNB4, CALM3, CAMK2A, CAMK2G, CCK, CD72, CDC42, CHN1, AP2M1, AP2S1, CLTA, CNP, COL2A1, COL3A1, COL4A3, COL4A4, COL4A5, COL5A1, COL5A2, COL6A2, COL6A3, COL9A1, COL9A3, CSF2, CSF2RB, CSNK2A1, CSNK2A2, DCC, DLG1, DLG3, DLX5, DNM1, DNM2, DPYSL3, HBEGF, ECM2, DUSP5, DUSP7, DUSP9, EFNA3, EFNA4, EFNA5, EFNB2, EGR2, EPHA2, CTTN, EPHA1, EPHA3, EPHA5, EPHA7, EPHA8, ERBB2, EREG, ETV1, ETV4, EXT1, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, GAP43, GATA3, GDI1, GDNF, GFRA1, GOLGA4, GPC1, GRB2, GRIN2A, ARHGAP35, NRG1, HES1, HSPA8, HSP90AA1, HSP90AB1, IL2RA, IL2RB, IL2RG, ISL1, ITGA1, ITGA2, ITGA5, ITGA9, ITGAV, KIF5A, KIT, KRAS, ABLIM1, LIMK1, MARK3, RAB8A, KITLG, NRAS, NRCAM, NRTN, NTF3, NTRK1, NTRK2, NTRK3, NTN3, OGN, OPHN1, OTX2, PEBP1, PAX2, PPP5C, PRKCQ, MAPK3, PSPN, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPRA, PTPRM, RAB3A, RAC2, RAF1, RASA2, RB1, RNF6, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RRAS, RYK, S100A6, S100B, SCN5A, SDCBP, SEMA3F, ITSN1, SHC1, SHH, SIAH1, SIAH2, SLIT1, SLIT3, SOD1, SOS1, SOS2, SPAST, SPTA1, SPTB, SRF, STXBP1, CNTN2, TBCE, TNR, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, CLRN1, VCL, VEGFA, EZR, XK, SEMA3B, FZD3, FGF23, RND2, USP9X, CUL3, SEMA7A, CNTNAP1, UNC5C, NUMB, PEA15, RAB11A, NRP2, ARHGEF7, PHOX2B, RPS6KA4, KALRN, RPS6KA5, SLIT2, SLC9A3R1, NRXN3, NRXN1, PSMF1, AATK, FEZ2, SEMA3E, IST1, FARP2, PSMD6, RBX1, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, PSME3, SPON2, SEC24B, OLFM1, VAV3, SLC9A6, CAP2, CAP1, STK25, SEMA6C, SEMA6B, SEMA4F, SEMA4B, ATG7, ARPC1A, DPYSL4, TBR1, CHL1, FRS3, VAX1, TWF2 |
1533 | GO:0042098 | 0.03 | 2.63 | 8.30 | 13 | 20 | T cell proliferation | BAX, CCND3, CD151, FYN, ITGAD, P2RX7, PIK3CG, PSMB10, SATB1, SLC11A1, TNFRSF4, TNFSF14, MALT1 |
1534 | GO:0045089 | 0.00 | 2.62 | 75.95 | 118 | 182 | positive regulation of innate immune response | AP1G1, BIRC3, XIAP, BTK, C1QBP, CALM3, CASP8, CD14, CD86, CD36, CHUK, ATF2, CTSK, CTSS, CYBA, CYLD, COCH, DMBT1, DUSP4, DUSP7, ELK1, EP300, EREG, F2RL1, FCER1G, FCN1, FYN, GFI1, HCK, UBE2K, HPX, ICAM2, IFI16, IL1B, IRAK1, IRAK2, IRF1, ITGAM, ITPR1, ITPR2, ITPR3, JUN, KRAS, LTF, NRAS, PDPK1, PIK3C3, PPP2R5D, PPP3R1, PRKACA, PRKACB, PRKACG, PRKCE, MAPK3, MAPK8, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PVR, RAF1, RELB, RPS6KA1, RPS6KA2, RPS6KA3, RPS19, RPS27A, SEC14L1, SKP1, STAT5B, SYK, TNFAIP3, TYRO3, UBB, UBE2D1, UBE2D2, UBE2V1, VAV1, CUL1, IKBKG, RIPK1, RIPK2, BCL10, PGLYRP1, UBA3, RPS6KA5, PSMF1, NR1D1, PUM1, PSMD6, TRIL, NR1H4, PSME3, TNIP1, CNPY3, MALT1 |
1535 | GO:0042088 | 0.02 | 2.62 | 9.60 | 15 | 23 | T-helper 1 type immune response | ANXA1, BCL3, CD80, HLX, IL18, RELB, XCL1, SLC11A1, TNFSF4, RIPK2, IL18R1, IL1RL1, IL27RA, IL18BP, EBI3 |
1536 | GO:2000027 | 0.00 | 2.62 | 23.68 | 37 | 57 | regulation of organ morphogenesis | ABL2, AGTR2, BAX, BCL2, BMPR1A, CHAD, CNTF, DAB2, CELSR2, ESR1, GPC4, GATA3, B4GALT1, HGF, HPN, IFNG, RBPJ, TACSTD2, PTK7, PTN, RAC1, RXRA, RYK, SNAI2, TNFAIP3, TWIST1, VDR, VEGFA, WNT11, FZD3, FZD6, FZD7, NUMB, GPC6, SEC24B, CARM1, SIX2 |
1537 | GO:0072507 | 0.00 | 2.62 | 90.98 | 141 | 218 | divalent inorganic cation homeostasis | ABL2, ADCYAP1R1, ADRA1B, ANXA6, ATP1A2, ATP2A1, ATP2B1, ATP2B2, ATP6V1B1, ATP7B, AVP, AVPR1B, BAX, BCL2, BDKRB2, BMP4, CACNA1A, CACNA1F, CACNB4, CALCR, CALM3, CASQ2, CAV3, CD4, CD36, CD38, CD40, CD52, CCR1, CCR3, CCR5, CCR8, CYBA, CYP27B1, CD55, DIAPH1, S1PR1, LPAR1, S1PR3, EDN2, EDN3, EDNRA, EDNRB, ESR1, F2R, F2RL1, GALR1, GLP1R, GNA15, GNAT2, GNB1, CCR10, XCR1, GRINA, GRM1, GSTM2, GTF2I, HEXB, HRC, HTR2C, IL1B, IL13, ITGB1, ITPR1, ITPR2, ITPR3, KCNA1, KCNA5, KCNK3, KDR, KISS1, KNG1, NTSR1, OXT, P2RX3, P2RX4, P2RX7, P2RY1, P2RY2, P2RY4, PARK2, PDE4D, PDPK1, PIK3CB, PIK3CG, PLN, PRKACA, PRKCA, PRKCB, PRKCE, PRKD1, PTH1R, PTPN6, PYGM, RAP1GDS1, RYR1, RYR2, RYR3, S100A8, S100A9, CCL21, XCL1, SLC8A1, SLC8A3, SLC11A1, SNCA, STC1, TAC1, TNNI3, TPT1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, VDR, TRPV1, WFS1, XK, SLC30A1, SLC30A2, CSRP3, TNFSF11, S1PR4, TRIM24, INPP4B, AP3D1, HAP1, RGN, SLC24A1, VAPB, GSTO1, AKAP6, ATG5, TRDN, CIB2, CHERP, CXCL13, SCGN, CCR9, CORO1A |
1538 | GO:0018105 | 0.00 | 2.62 | 30.76 | 48 | 74 | peptidyl-serine phosphorylation | ADRBK1, ATM, ATR, BAX, BDKRB2, CAMK4, CAMK2A, CCNB1, CSNK1D, CSNK1G2, CSNK1G3, DCX, DYRK1A, ERN1, HRC, ILK, SMAD7, PDE4D, PDPK1, PRKAA1, PRKACA, PRKCA, PRKCB, PRKCE, PRKCG, PRKCI, PRKCQ, PRKCZ, MAPK3, MAPK8, PRKX, RPS6KA2, SGK1, AURKA, SYK, VRK1, OGT, MAPKAPK5, TNKS, RIPK1, RPS6KA4, AURKB, RPS6KA5, EIF2AK3, RASSF2, SGK2, CHEK2, STK38 |
1539 | GO:0071346 | 0.03 | 2.62 | 8.31 | 13 | 20 | cellular response to interferon-gamma | ASS1, CD58, EPRS, GAPDH, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, STAR, XCL2 |
1540 | GO:0043433 | 0.00 | 2.62 | 33.39 | 52 | 80 | negative regulation of sequence-specific DNA binding transcription factor activity | NR0B1, ANXA4, CAT, CDKN2A, CEBPG, CMKLR1, CYLD, ESR1, FLNA, GAS6, GFI1, FOXA2, PRMT2, IGF1R, IRAK1, IRAK2, SMAD7, MEN1, PBX1, PEX14, PIM1, PROX1, PTCH1, PTGIS, PTHLH, RB1, RNF2, XCL1, SFRP4, SFRP5, SP100, TNFAIP3, TWIST1, TNFSF4, TNFRSF4, SUMO1, WFS1, FZD6, NR0B2, HDAC3, TAX1BP1, KLF4, HAND1, HAND2, HDAC4, TRIB1, MAD2L2, SIVA1, RBCK1, ZNF234, WWP2, PHB2 |
1541 | GO:0002694 | 0.00 | 2.61 | 95.57 | 148 | 229 | regulation of leukocyte activation | ADA, ADK, AP1G1, AHR, ANXA1, ATM, AXL, BAD, BCL2, PRDM1, BMP4, BPI, BTK, CAMK4, CBLB, CD2, CD3D, CD3G, CD4, CD5, CD6, CD28, CD80, CD86, CD37, CD38, CD40, CD59, CD74, CDC42, CDKN1A, CDKN2A, CHRNB2, CLC, CNR1, CNR2, CTLA4, CYLD, CD55, DHPS, DLG1, DPP4, DTX1, GPR183, EFNB2, EGR3, ERBB2, F2RL1, FCER1A, FCER1G, FGR, FLOT2, FLT3, FLT3LG, FYN, GAS6, GATA3, GRB2, HLA-DQA1, HLX, HES1, IFNA2, IFNG, IGF1, IGF2, IGFBP2, IHH, IL1B, IL2RA, IL10, IL13, IL18, IDO1, INHA, IRF1, ITGAL, ITPKB, LMO1, CD46, PAWR, PDPK1, PRKAR1A, PRKCQ, PRKCZ, PTAFR, PTPN6, PTPRE, RAC1, RAC2, RAG1, RARA, CCL21, XCL1, SFTPD, SHH, SNCA, SOD1, SOS1, SOS2, SOX11, SPN, SPTA1, STAT5B, STXBP2, SYK, TAC1, TNFAIP3, TRAF2, TNFSF4, TNFRSF4, TYRO3, SCGB1A1, UNG, VAV1, WHSC1, ZP3, FOXN1, AP3B1, TNFSF11, PDE5A, VAMP8, TNFSF14, TNFSF13, TNFSF9, RIPK2, IL1RL2, CD84, VNN1, BCL10, AP3D1, PGLYRP1, TNFSF18, IL1RL1, SOCS6, IL27RA, SOX13, GAB2, EBI3, RNF41, IKZF1, VAV3, TNFSF13B, MALT1, SPINK5, GLMN, HHLA2, CORO1A, VSIG4 |
1542 | GO:0071216 | 0.00 | 2.61 | 40.48 | 63 | 97 | cellular response to biotic stimulus | ABCA1, ARG1, ASS1, AXL, PRDM1, BMP6, BYSL, TSPO, CD6, CD14, CD80, CD86, CD36, SCARB1, ENTPD2, CD40, CEBPE, CCR5, CSF2, CX3CR1, CD55, EDNRB, GFI1, HCK, HIF1A, HMGCS2, ICAM1, IFNG, IL1B, IL10, IL18, IRAK1, IRAK2, LTF, CD180, P2RY2, SERPINE1, PDE4B, PDE4D, PRKCA, PRKCE, MAPK3, MAPK8, PTAFR, RARA, CCL20, STAR, SYK, TNFAIP3, TNFRSF1B, TNFSF4, WFS1, FZD5, OGT, ADAM9, RIPK2, EIF2AK3, LITAF, NR1D1, TRIB1, SPON2, TXNIP, IL24 |
1543 | GO:0046390 | 0.00 | 2.61 | 60.51 | 94 | 145 | ribose phosphate biosynthetic process | ABCA1, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADCYAP1R1, ADK, ADORA2A, ADRB2, ADSL, ADSS, AK2, AK4, AMPD1, AMPD2, APLP1, APRT, AQP1, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, AVP, AVPR2, CALCR, CALM3, DHODH, LPAR1, EDNRA, EDNRB, FSHR, GALR1, GCG, GHRH, GHRHR, GLP1R, GNAI3, GNAL, GNAS, GRM8, GUCA1A, GUCA1B, GUCA2A, GUCA2B, GUCY1B3, GUCY2C, GUCY2F, GUK1, GUCY2D, HPRT1, HTR2C, IMPDH1, IMPDH2, INSL3, LDHC, NTRK1, NTRK2, P2RY11, PRKCA, PRPS2, PTGER4, PTHLH, PYGL, RAF1, RCVRN, STAT3, SURF1, UCN, UPP1, VIP, VIPR2, WFS1, PAPSS2, PAPSS1, AKAP6, ATP5J2, GABBR2, GUCA1C, SLC25A13, CALCRL, RAMP2, ATP5H, CAP2, CAP1, ATP5L, SLC26A1, ACOT7 |
1544 | GO:0002703 | 0.03 | 2.61 | 8.32 | 13 | 20 | regulation of leukocyte mediated immunity | BST2, BTK, CLC, CR1, ICAM1, IFNA2, IGF2, IL10, SERPINB9, PTPN6, SERPINB4, SPN, IL27RA |
1545 | GO:2000379 | 0.03 | 2.61 | 8.32 | 13 | 20 | positive regulation of reactive oxygen species metabolic process | TSPO, CD36, CDKN1A, CRP, GADD45A, F2RL1, GRB2, SNCA, SOD1, AKR1C3, RIPK1, RGN, RNF41 |
1546 | GO:0099536 | 0.00 | 2.61 | 169.85 | 261 | 407 | synaptic signaling | ABAT, ACHE, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADORA1, ADRB2, AP2A1, AP2B1, ALDH2, AMPH, ARF1, ATP1A2, ATP2B2, BCHE, HCN2, TSPO, CA2, CA7, CACNA1A, CACNA1B, CACNA1E, CACNB4, CALM3, CAMK4, CAMK2A, CAMK2G, CD38, CDC20, CDH8, CDK5, CHRM1, CHRM3, CHRNB2, CHRNB4, AP2M1, AP2S1, CLCN3, CNP, CNR1, CNR2, COMT, CORT, CTNND2, CX3CR1, DBH, DBI, DBN1, DLG1, DLG2, DLG3, DNM1, DTNA, EGR2, EGR3, EIF4EBP2, SLC29A1, ETV5, FNTA, GABRA4, GABRB2, GABRG1, GABRR1, GABRR2, GAD1, GAD2, GDNF, GFAP, GIP, GLRA1, GLRA2, GLRB, GLS, GLUL, GNAI1, GNAI3, GNAL, GNB1, GNB2, GNGT1, GNGT2, GPM6B, GPR1, GRIA1, GRIA4, GRID2, GRIK3, GRIN2A, GRM1, HRH1, HRH2, HSPA8, HTR2C, HTR3A, IFNG, ITPR3, KCNA1, KCNA2, KCNA3, KCNA4, KCNA5, KCNA10, KCND2, KCND3, KCNJ2, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ12, KCNJ14, KCNJ15, KCNJ16, KCNK2, KCNK3, KCNN1, KCNN4, KCNQ1, KCNS1, KCNS2, KCNS3, KIF5A, KISS1, KIT, KRAS, RAB8A, ATXN3, NTF3, NTRK1, NTRK2, NTSR1, OMP, OPHN1, OXT, P2RX3, P2RX4, P2RX7, P2RY11, PARK2, PCDH8, PDPK1, PDYN, PFN2, SEPT5, PPT1, PRKACB, PRKCA, PRKCB, PRKCE, PRKCG, PRKCZ, RELN, PTGER4, PTN, PTPRN2, RAB3A, RAB3B, RAC1, RAC3, RAF1, RAP1A, RARA, RPS6KA1, RPS6KA2, RPS6KA3, RRAS, S100B, SCN2B, CX3CL1, SDCBP, SLC1A6, SLC1A7, SLC6A2, SLC6A4, SLC6A11, SLC6A12, SLC6A13, SLC8A3, SLC12A4, SLC18A1, SLC22A2, SNAP25, SNCB, SNCA, SRF, STAR, STAU1, STXBP1, ABCC8, SYN1, SYP, SYPL1, SYT1, SYT4, TAC1, TACR2, CNTN2, NR2E1, TNR, UCN, VIPR1, YWHAG, YWHAH, SLC30A1, LRP8, SYN3, DOC2A, KCNAB2, CADPS, STX11, RAB11A, SNAP23, LIN7A, SYNJ1, BSN, HAP1, USP14, SLC6A5, DGKI, KCNAB3, GPR52, S1PR2, SNAP29, CPNE6, NRXN3, NRXN1, NRXN2, KCNK6, PICK1, APBA3, GABBR2, CARTPT, RIN1, SNCAIP, RAPGEF2, RIMS2, SNPH, RIMS3, SNAP91, HCN4, ABCC9, AKAP9, KCNMB2, CACNG2, BAIAP2, UNC13B, RGS14, CSPG5, GIPC1, CPLX2, CPLX1, CACFD1, GPR176, PTGDR2, HRH3, GABARAP |
1547 | GO:0031667 | 0.01 | 2.61 | 11.46 | 18 | 28 | response to nutrient levels | AKT2, CYBA, GSS, HTR2C, ICAM1, IGF2, NTRK1, PAX2, PROX1, PYY, PSPH, SLC22A3, SOD1, SORD, TRPV1, WNT11, AIFM1, SLIT2 |
1548 | GO:0002274 | 0.00 | 2.61 | 15.38 | 24 | 37 | myeloid leukocyte activation | ADAM10, BPI, CAMK4, CD2, CD86, CD37, CD74, CLU, CSF2, EDN2, FLT3LG, RBPJ, IL10, JUN, RELB, CX3CL1, SLC11A1, SNCA, TRPV1, TNFSF9, ADAM9, IL1RL1, DHRS2, BATF |
1549 | GO:0090066 | 0.00 | 2.60 | 112.68 | 174 | 270 | regulation of anatomical structure size | ACTA2, ADCY6, ADD1, ADORA1, ADRA1B, ADRA2C, ADRB2, AGTR2, ALOX12, SHROOM2, AQP1, ARF1, ARF6, ARHGAP4, ARHGAP5, ATP1A2, ATP2B2, AVP, AVPR1B, AVPR2, BBS2, BBS4, BDKRB2, BMPR2, CAPZA1, CAPZB, CAV3, CD38, CDK4, CDK5, CFL2, CHRM1, CHRM3, CLCN3, CLCN6, CLNS1A, CPS1, CRP, DBH, DCC, ACE, DLG1, DNM2, E2F4, EDN2, EDN3, EDNRA, EDNRB, EFNA5, CTTN, EPHA7, EPS8, F2R, F2RL1, FGA, FGG, GJA5, GOLGA4, GPX1, GRB2, HCK, HCLS1, NRG1, HIF1A, HMGCR, HRH1, HRH2, HSP90AB1, ICAM1, ILK, INS, ITGA1, KCNA5, KCNJ8, KCNN4, KNG1, LIMK1, NRCAM, NTRK3, NTS, P2RX4, P2RX7, P2RY1, P2RY2, PAX2, PFN1, PFN2, PIK3C2A, PRKCE, PRKCQ, PRKG1, PTAFR, PTGS1, PTPRM, RAB3B, RAC1, RDX, RGS2, RNF6, CCL21, CCL24, CX3CL1, SEMA3F, SHC1, SLC6A4, SLC6A12, SLC8A1, SLC12A4, SNTA1, SOD1, SOD2, SPTA1, SPTB, SRF, CDKL5, CNTN2, TMOD1, TNR, TP73, TSC1, UCN, VAV1, VEGFA, VIL1, EZR, VIP, XK, SEMA3B, RND2, OGT, SEMA7A, RAB11A, PEX11A, KAT2B, WASF1, LATS1, ITGB1BP1, SLIT2, SLC9A3R1, PICK1, ATG5, BAG4, GMFG, AATK, SEMA3E, IST1, RB1CC1, WDR1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, ABI2, KCNMB2, SEMA3A, RAPGEF3, CDC42EP2, OLFM1, VAV3, BAIAP2, SEMA6C, SEMA6B, SEMA4F, SEMA4B, ARPC1A, ARFGEF1, CDC42EP3, AVIL, CDC42EP1, CORO1A, SNF8, TWF2 |
1550 | GO:0055013 | 0.03 | 2.60 | 8.34 | 13 | 20 | cardiac muscle cell development | BMP4, CCNB1, CXADR, PROX1, SGCB, SLC8A1, SRF, VEGFA, CSRP3, ATG5, SPEG, ATG7, BVES |
1551 | GO:0007268 | 0.00 | 2.60 | 101.24 | 157 | 245 | synaptic transmission | ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADRB2, AP2A1, AP2B1, ALDH2, AMPH, ATP1A2, ATP2B2, HCN2, TSPO, CACNA1E, CACNB4, CALM3, CAMK4, CAMK2G, CDC20, CDH8, CHRM3, AP2M1, AP2S1, CLCN3, CNP, CNR1, COMT, CORT, CTNND2, DBH, DBN1, DLG1, DLG2, DLG3, EGR2, EIF4EBP2, SLC29A1, FNTA, GABRA4, GABRB2, GABRG1, GABRR1, GABRR2, GDNF, GLRA1, GLRA2, GLRB, GNAI3, GNAL, GNB1, GNB2, GNGT1, GNGT2, GPR1, GRIA4, GRID2, GRM1, HRH1, HRH2, HTR2C, HTR3A, KCNA1, KCNA2, KCNA3, KCNA4, KCNA5, KCNA10, KCND2, KCND3, KCNJ2, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ12, KCNJ14, KCNJ15, KCNJ16, KCNK2, KCNK3, KCNN1, KCNN4, KCNQ1, KCNS1, KCNS2, KCNS3, KIF5A, KIT, KRAS, RAB8A, ATXN3, OMP, OPHN1, P2RX4, P2RY11, PCDH8, PDPK1, PDYN, PRKACB, PRKCA, PRKCB, PRKCG, RAC1, RAC3, RAF1, RARA, RPS6KA1, RPS6KA2, RPS6KA3, RRAS, SCN2B, CX3CL1, SDCBP, SLC6A2, SLC12A4, SNCB, STAR, ABCC8, SYP, SYPL1, CNTN2, UCN, VIPR1, YWHAG, YWHAH, LRP8, KCNAB2, RAB11A, BSN, USP14, SLC6A5, KCNAB3, GPR52, CPNE6, KCNK6, APBA3, GABBR2, CARTPT, RIN1, RAPGEF2, SNAP91, HCN4, ABCC9, AKAP9, KCNMB2, CACNG2, BAIAP2, CSPG5, GIPC1, CACFD1, GPR176, PTGDR2, GABARAP |
1552 | GO:0050850 | 0.03 | 2.60 | 8.34 | 13 | 20 | positive regulation of calcium-mediated signaling | ADA, CALM3, CD4, CD8A, FCER1A, GSTM2, ITGAL, P2RX3, P2RX4, SYK, HAP1, GSTO1, TRDN |
1553 | GO:0002208 | 0.03 | 2.60 | 8.35 | 13 | 20 | somatic diversification of immunoglobulins involved in immune response | CD28, CD40, ERCC1, IFNG, IL10, TNFSF4, UNG, WHSC1, TNFSF13, RNF8, EXO1, IL27RA, BATF |
1554 | GO:0007628 | 0.03 | 2.60 | 8.35 | 13 | 20 | adult walking behavior | CACNA1A, CACNB4, CTNS, EPHA4, GLRA1, GLRB, KCNJ10, SCN1A, SCN8A, CNTN2, TRH, ZIC1, ATG7 |
1555 | GO:0010837 | 0.03 | 2.60 | 8.35 | 13 | 20 | regulation of keratinocyte proliferation | KLF9, CDH3, CTSV, EFNB2, FGF7, SFN, HAS2, REG3A, PRKD1, SRSF6, SNAI2, VDR, TP63 |
1556 | GO:0016447 | 0.03 | 2.60 | 8.35 | 13 | 20 | somatic recombination of immunoglobulin gene segments | CD28, CD40, ERCC1, IFNG, IL10, TNFSF4, UNG, WHSC1, TNFSF13, RNF8, EXO1, IL27RA, BATF |
1557 | GO:0045190 | 0.03 | 2.60 | 8.35 | 13 | 20 | isotype switching | CD28, CD40, ERCC1, IFNG, IL10, TNFSF4, UNG, WHSC1, TNFSF13, RNF8, EXO1, IL27RA, BATF |
1558 | GO:0045777 | 0.03 | 2.60 | 8.35 | 13 | 20 | positive regulation of blood pressure | ADH5, ADORA1, ADRA1B, ADRB2, AVP, AVPR2, CNR1, CYBA, GLP1R, OXT, PDE4D, TACR3, CARTPT |
1559 | GO:0051220 | 0.03 | 2.60 | 8.35 | 13 | 20 | cytoplasmic sequestering of protein | TSPO, FLNA, HK2, IL10, TONSL, TRIP6, TNFSF14, LATS1, TACC3, CREB3, KDELR1, OS9, KDELR3 |
1560 | GO:0043281 | 0.00 | 2.60 | 21.18 | 33 | 51 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | ALOX12, BAD, BID, BOK, CASP9, CCK, CDKN2A, COL4A3, CTGF, EPHA7, F2R, F3, HIP1, MAP3K5, MGMT, SLC11A2, REST, RPS3, S100A8, S100A9, SOX2, TP63, CRADD, BCL10, AIFM1, EIF2AK3, KIAA0141, TNFSF15, CASP8AP2, PDCD6, BCL2L10, BCL2L11, ARL6IP5 |
1561 | GO:0007162 | 0.05 | 2.59 | 7.05 | 11 | 17 | negative regulation of cell adhesion | ACP5, ADAM10, ANGPT1, ARHGDIB, ARHGDIG, CLDN7, HRG, TNC, KNG1, PDE3B, SIPA1 |
1562 | GO:0010646 | 0.00 | 2.59 | 46.42 | 74 | 120 | regulation of cell communication | ACHE, ACTL6A, ARF1, ATP1A2, ATP2B2, BCHE, BNIP3L, TSPO, CA2, CA7, CDC20, CHRNB2, CHRNB4, CNR2, CSNK2A2, CTSK, CXADR, DBI, DBN1, EGR2, EIF4EBP2, KAT2A, GFAP, GJA5, GLRA1, GPM6B, GRIA1, GRIK3, HRH1, HRH2, ITGA2, KCNJ10, RAB8A, OXT, PAFAH1B2, PFN2, PIP4K2A, SEPT5, PTN, RAB3A, RAB3B, RARA, RPL28, RYR2, SLC6A4, SLC8A3, SLC18A1, SRF, STAR, STAU1, SYN1, SYT1, NR2E1, TNR, U2AF1, ZBTB17, SLC30A1, LRP8, SYN3, RAB11A, SYNJ1, RAB33A, PICK1, ATG5, RIN1, SNCAIP, FEZ2, RUBCN, RIMS3, BAIAP2, ATG7, SPTLC1, CSPG5, CPLX2 |
1563 | GO:0006303 | 0.00 | 2.59 | 15.44 | 24 | 37 | double-strand break repair via nonhomologous end joining | ATM, BARD1, BRCA1, SETMAR, UBE2V2, SUMO1, UVRAG, WHSC1, XRCC4, HIST1H4I, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HERC2, RNF8, BRE, DCLRE1A, RAD50 |
1564 | GO:0046034 | 0.05 | 2.59 | 7.06 | 11 | 17 | ATP metabolic process | AK4, AMPD2, ATP1A2, ATP6V1A, ATP6V1B1, ATP6V1B2, BAD, TSPO, CTNS, GUK1, HSPA8 |
1565 | GO:0002764 | 0.00 | 2.58 | 145.23 | 223 | 348 | immune response-regulating signaling pathway | ACTB, ACTG1, ADA, ANGPT1, BIRC3, XIAP, BAD, BAX, BCL2, BLK, BTK, C1QBP, CACNA1F, CACNB4, CALM3, CAMK2A, CAMK2G, CASP8, CASP9, CBLB, CD3D, CD3G, CD4, CD14, CD28, CD80, CD86, CD36, CD38, CD40, CD79B, CDC42, CDKN1A, CHUK, CR1, CR2, ATF2, CSF2, CSF2RB, CTLA4, CTSK, CTSS, CYBA, CYLD, DMBT1, HBEGF, DUSP4, DUSP5, DUSP7, DUSP9, ELF1, ELK1, EP300, ERBB2, EREG, F2RL1, FCER1A, FCER1G, FCGR1B, FCGR2A, FCGRT, FCN1, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FGR, FYB, FYN, GATA3, GFI1, GPLD1, GRB2, GRIN2A, HCK, NRG1, HLA-DQA1, NR4A1, HSP90AA1, HSP90AB1, ICAM2, IL1B, IL2RA, IL2RB, IL2RG, IRAK1, IRAK2, IRF1, ITGAM, ITPR1, ITPR2, ITPR3, JUN, KCNN4, KIT, KRAS, LIMK1, LTF, MARK3, KITLG, FOXO4, NRAS, PEBP1, PAWR, PDE4B, PDE4D, PDPK1, PIGR, PIK3C3, PIK3CB, PPP2R5D, PPP3R1, PPP5C, PRKACA, PRKACB, PRKACG, PRKCB, PRKCE, PRKCQ, MAPK3, MAPK8, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN6, PTPRA, PTPRJ, RAC1, RAF1, RASA2, RELB, RPS6KA1, RPS6KA2, RPS6KA3, RPS6KB2, RPS27A, SEC14L1, SHC1, SKP1, SOS1, SPTA1, SPTB, STK11, SYK, TNFAIP3, TSC2, TYRO3, UBB, UBE2D1, UBE2D2, UBE2V1, VAV1, EZR, LAT2, FGF23, CUL3, CUL1, IKBKG, PEA15, RIPK1, RIPK2, BCL10, PGLYRP1, UBA3, RPS6KA5, THEMIS2, PSMF1, BCAR1, NR1D1, RAPGEF2, PUM1, ELMO1, GAB2, PSMD6, TRIL, NR1H4, RBX1, ABI1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, WASF2, PSME3, TNIP1, VAV3, BAIAP2, ARPC1A, RBCK1, CNPY3, FRS3, MALT1 |
1566 | GO:0030336 | 0.00 | 2.58 | 41.29 | 64 | 99 | negative regulation of cell migration | ACVRL1, ADA, ADARB1, ADORA1, AGTR2, ALOX15B, ANGPT2, APOH, ARHGAP4, ARHGDIB, BCL2, BST2, C5, KRIT1, CD63, CX3CR1, DCN, DPEP1, DPYSL3, EPHA1, HAS1, HRG, IGFBP3, IGFBP5, ILK, KRT16, TACSTD2, SMAD7, SERPINE1, SERPINF1, PFN2, PTGER4, PTN, PTPRJ, PTPRM, PTPRR, RAP2A, RAP2B, RRAS, CCL21, CCL25, SHH, SP100, SRF, STC1, NR2F2, VCL, WNT11, RECK, CHRD, ADAM15, ITGB1BP1, KLF4, SLIT2, SLC9A3R1, PTPRU, RNF41, TRIB1, CITED2, SEMA3A, CXCL13, IL24, ABHD2, STRAP |
1567 | GO:0022408 | 0.05 | 2.58 | 7.07 | 11 | 17 | negative regulation of cell-cell adhesion | ABL2, APOA1, CDH1, IL1RN, EPCAM, SNAI2, TNR, WNT1, KLF4, MAD2L2, SPINT2 |
1568 | GO:0051674 | 0.00 | 2.58 | 302.15 | 457 | 724 | localization of cell | AAMP, ABL2, ACP5, ACTN4, ACVR1, ACVR1B, ACVRL1, ADA, ADAM10, ADARB1, ADCY3, ADORA1, AGTR2, AKT2, ALOX12, ALOX15B, ANG, ANGPT1, ANGPT2, ANXA1, ANXA3, ANXA5, APC, APOA1, APOH, SHROOM2, AQP1, ARF4, ARHGAP4, ARHGAP5, ARHGDIB, ASTN1, RERE, ATOH1, ATP1B3, AXL, BAX, BBS2, BBS4, BCL2, BMP4, BMPR2, DST, BSG, BST2, BTG1, TSPO, C1QBP, C5, CACNA1E, CCK, KRIT1, CD2, SCARB1, CD44, CD48, CD58, CD63, CD74, CD151, CDC42, CDK5, CDK6, CGA, CCR1, CCR5, CMKLR1, COL1A1, COL3A1, COL5A1, CLDN7, VCAN, CSPG4, CTGF, CTNNA1, CTNNA2, CX3CR1, CXADR, DAB2, DBH, DCC, DCN, ACE, DCX, DIAPH1, DNAH5, DNAH8, DPEP1, DPP4, DPYSL3, HBEGF, ECM1, S1PR1, LPAR1, EDN2, EDN3, EDNRA, EDNRB, EFNA1, EFNB2, CELSR2, EGR3, EPHA2, EMP2, CTTN, EMX2, ENPEP, EPHA1, EPHA3, EPHA4, EPHA8, EPHB1, EPHB3, EPS8, ERG, ETS1, F2R, F2RL1, F3, F7, F10, FAP, FBLN1, EFEMP1, FCER1G, FGF1, FGF7, FGF8, FGFR4, FGR, FLT1, FLT4, FUT8, FYN, GAS6, GAS8, GATA3, GDNF, B4GALT1, GPLD1, GPM6A, GPR15, GPX1, GRB2, GRB7, CXCL1, CXCL2, CXCL3, HIST1H1T, HAS1, HAS2, HCK, HEXB, HGF, NRG1, HIF1A, NR4A1, ONECUT1, HRH1, HRG, HES1, HSPB1, ICAM1, IFNG, IGF1, IGF1R, IGFBP3, IGFBP5, IL1B, IL10, ILK, ING2, INS, INSL3, ITGA6, ISL1, ITGA1, ITGA2, ITGA3, ITGA4, ITGA5, ITGA7, ITGA9, ITGAL, ITGAM, ITGAV, ITGAX, ITGB1, ITGB4, JUN, JUP, KDR, KIT, KRAS, KRT2, KRT16, LAMA3, LAMA4, LAMA5, LDHC, TACSTD2, EPCAM, SMAD3, SMAD7, SMCP, KITLG, NRAS, NRCAM, NRTN, NTF3, NTRK2, NTRK3, DDR2, OGDH, OLR1, OPHN1, P2RY1, P2RY2, P2RY6, SERPINE1, PAWR, PCM1, PDE4B, PDE4D, ENPP2, PDPK1, SERPINF1, PF4, PF4V1, PFN1, PFN2, PGK2, PIK3C2A, PIK3C2B, PIK3CB, PIK3CG, PRCP, PRKCA, PRKCE, PRKCI, PRKD1, PRKCQ, PRKCZ, PRKG1, PRKX, PROC, PROS1, PROX1, RELN, PSG2, PTAFR, PTGER4, PTK7, PTN, PTPN6, PTPRJ, PTPRM, PTPRR, PTPRZ1, RAB1A, RAB13, RAC1, RAC2, RAF1, RAP2A, RAP2B, RDX, RFX3, RPS19, RRAS, RREB1, S100A2, S100A8, S100A9, S100A12, S100P, SAA4, SERPINB3, SCNN1B, CCL20, CCL21, CCL22, CCL24, CCL25, CXCL6, CXCL5, XCL1, CX3CL1, SDC1, SDC2, SDC4, SDCBP, SELE, SELL, SELP, SELPLG, SEMA3F, SEMG1, SFTPD, SGK1, SHC1, SHH, SIX1, SIX3, SLC8A1, SLC9A1, SLC16A1, SNAI2, SNAI1, SORD, SORL1, SOS1, SOX1, SOX9, SOX10, SP100, SPARC, SPN, SRF, SRMS, STAT3, STAT5B, STC1, CDKL5, STK10, XCL2, SYK, T, TAC1, CNTN2, NR2F1, NR2F2, NR2E1, TMF1, TNP2, TNR, TNS1, TRIP6, TWIST1, TYK2, TYRO3, CLRN1, VAV1, VCL, VEGFA, VEGFB, VEGFC, VIL1, VTN, WNT11, ZP3, PTP4A1, LRP8, SCG2, SEMA3B, FZD3, ARHGEF5, CUL5, SLC7A5, MADCAM1, USP9X, USP9Y, EPX, SOX14, RECK, CUL3, FOXN1, SORBS2, CDC42BPA, SEMA7A, IKBKAP, TNFSF11, DNAH17, UNC5C, DCHS1, CHRD, NUMB, DNAH11, TNFSF14, TNFSF12, ADAM15, ADAM9, RAB11A, TNFRSF18, NRP2, CD84, AKAP4, ARHGEF7, SGPL1, PHOX2B, CDK5R2, TNFSF18, DOK2, PSTPIP2, PSTPIP1, RGN, DCLK1, ITGB1BP1, KLF4, TAOK2, CER1, SLIT2, SLC9A3R1, HAND2, ONECUT2, BAG4, CXCL14, BCAR1, CDC42BPB, SDC3, RAPGEF2, SEMA3E, SLK, HDAC4, ZEB2, ELMO1, GAB2, KIAA0319, HDAC6, PDCD6, PTPRU, GPC6, ARPC5, TSPAN1, ABI2, WASF2, TNK2, RNF41, TRIB1, APC2, CITED2, SEMA3A, ATP8A1, RAPGEF3, OLFM1, VAV3, CAP1, CREB3, SEMA6C, SEMA6B, SEMA4F, SEMA4B, PROCR, CXCL13, PDPN, SPINT2, NRG3, SIX2, CHL1, GIPC1, IL24, VAX1, ABHD2, SLC7A9, BVES, CORO1A, STRAP |
1569 | GO:0071482 | 0.00 | 2.58 | 28.38 | 44 | 68 | cellular response to light stimulus | AQP1, ATF4, ATR, BAX, CALM3, CASP9, CDKN1A, CNGA1, CRY1, CRY2, DDB1, DDB2, EIF2S1, EP300, ERCC4, FNTA, GNAT1, GNB1, GNGT1, GUCA1A, GUCA1B, GUCY2F, GUCY2D, HIF1A, PDE6G, PPID, PRKCA, PRKCQ, PTN, RCVRN, RPGR, RS1, SAG, STK11, TP73, XPC, CUL4B, TP63, RGS9, SLC24A1, AURKB, GUCA1C, CERS1, RUVBL2 |
1570 | GO:2000134 | 0.00 | 2.58 | 28.38 | 44 | 68 | negative regulation of G1/S transition of mitotic cell cycle | ATM, CCND1, BCL2, CDKN1A, PRMT2, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RB1, RPS27A, SMARCA4, SOX4, TP73, UBB, TP63, CRADD, PSMF1, PSMD6, CTDSP2, PSME3, CTDSPL |
1571 | GO:0071347 | 0.01 | 2.57 | 14.18 | 22 | 34 | cellular response to interleukin-1 | BYSL, CHI3L1, HAS2, HIF1A, HSPA9, ICAM1, P2RY2, PAWR, PPP4C, PTGER4, PTGIS, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SOX9, XCL2, KLF2, ADAMTS7 |
1572 | GO:0051492 | 0.05 | 2.57 | 7.08 | 11 | 17 | regulation of stress fiber assembly | ARHGAP6, BBS4, S1PR1, TACSTD2, PFN1, PTGER4, SLC9A1, TSC1, ALMS1, WASF2, SYNPO |
1573 | GO:0051668 | 0.05 | 2.57 | 7.08 | 11 | 17 | localization within membrane | ARF1, CD2, COPA, COPB1, MAL, PRKCI, RAC1, RALA, COPB2, ATP8A1, COPE |
1574 | GO:0009948 | 0.05 | 2.57 | 7.08 | 11 | 17 | anterior/posterior axis specification | BMP4, CDX1, CDX2, CDX4, GPC3, RNF2, SHH, AURKA, KDM6A, CER1, SIX2 |
1575 | GO:2000243 | 0.05 | 2.57 | 7.09 | 11 | 17 | positive regulation of reproductive process | ACVR1B, C1QBP, GLRA1, OVOL1, PDE3A, PTAFR, PTGER4, SHH, AURKA, ZP3, PDE5A |
1576 | GO:0043647 | 0.01 | 2.57 | 14.19 | 22 | 34 | inositol phosphate metabolic process | ADCYAP1R1, CALM3, HRH1, IMPA1, IMPA2, INPP1, INPP4A, INPPL1, ITPKB, NTSR1, OCRL, P2RY1, PTAFR, PTH1R, SCP2, SNCA, INPP4B, SYNJ1, MINPP1, PPIP5K1, IP6K1, NUDT3 |
1577 | GO:0046164 | 0.01 | 2.57 | 14.19 | 22 | 34 | alcohol catabolic process | ALDH2, ALDH1B1, ALDH3B2, SCARB1, CYP24A1, CYP27B1, GK, GK2, GPD2, IMPA1, IMPA2, INPP1, NTSR1, ENPP2, SMPD1, SORD, FGF23, AKR1C3, SYNJ1, SNX17, SMPDL3A, NUDT3 |
1578 | GO:0019439 | 0.01 | 2.57 | 11.56 | 18 | 28 | aromatic compound catabolic process | AMBP, AOX1, BLVRA, BLVRB, CCBL1, COMT, CYP2A6, DBH, DIO3, GSTZ1, HAL, HPD, IDO1, PAH, QDPR, TAT, KYNU, ALDH1L1 |
1579 | GO:0061178 | 0.05 | 2.57 | 7.09 | 11 | 17 | regulation of insulin secretion involved in cellular response to glucose stimulus | CACNA1E, EFNA5, EPHA5, HMGCR, FOXA2, CDK16, PRKCE, HMGN3, NRXN1, NR1D1, NR1H4 |
1580 | GO:0009612 | 0.00 | 2.57 | 30.29 | 47 | 73 | response to mechanical stimulus | ANGPT2, ASNS, ATP2B2, BGLAP, CCNB1, ENTPD2, CHI3L1, CLCN6, COL3A1, COL11A1, DCN, ETS1, ETV1, F3, FYN, GATA4, GFI1, HPN, TNC, IGF1, IGFBP2, JUNB, JUND, JUP, KCNA1, KCNA5, KCNK2, KIT, NTRK1, NTRK2, P2RX3, P2RX7, P2RY1, PAWR, EIF2AK2, PSPH, PTCH1, SLC12A2, SMPD2, SOX2, UCN, XPA, XPC, FOSL1, NRXN1, NRXN2, TXNIP |
1581 | GO:0000715 | 0.05 | 2.56 | 7.09 | 11 | 17 | nucleotide-excision repair, DNA damage recognition | DDB1, DDB2, RPS27A, UBB, XPC, CUL4B, CUL4A, COPS3, RBX1, COPS8, COPS6 |
1582 | GO:0003401 | 0.05 | 2.56 | 7.09 | 11 | 17 | axis elongation | AREG, BMP4, ESR1, FGF1, TNC, PTK7, SHH, SIX1, SOX9, WNT11, TRIM28 |
1583 | GO:0006693 | 0.05 | 2.56 | 7.09 | 11 | 17 | prostaglandin metabolic process | ACOX1, ANXA1, AVP, CD74, EDN2, HPGD, PTGIS, PTGS1, TNFRSF1A, AKR1C3, PDPN |
1584 | GO:0043267 | 0.05 | 2.56 | 7.09 | 11 | 17 | negative regulation of potassium ion transport | ATF4, CASQ2, CAV3, KCNA5, KCNE1, KCNQ1, SUMO1, VIP, OXSR1, KCNE2, KCNE3 |
1585 | GO:0043516 | 0.05 | 2.56 | 7.09 | 11 | 17 | regulation of DNA damage response, signal transduction by p53 class mediator | ATM, ATR, CD44, CD74, CDKN2A, DDX5, DYRK1A, HIC1, SNAI2, SNAI1, TWIST1 |
1586 | GO:0045879 | 0.05 | 2.56 | 7.09 | 11 | 17 | negative regulation of smoothened signaling pathway | RUNX2, FGFR3, GPC3, PRKACB, PTCH1, RB1, RFX4, SALL1, TULP3, PTCH2, CHRD |
1587 | GO:0050856 | 0.05 | 2.56 | 7.09 | 11 | 17 | regulation of T cell receptor signaling pathway | ADA, CACNA1F, CBLB, ELF1, KCNN4, PAWR, PTPN6, PTPRJ, EZR, BCL10, MALT1 |
1588 | GO:0010959 | 0.00 | 2.55 | 57.03 | 88 | 137 | regulation of metal ion transport | ACTN4, ADCYAP1R1, ARF1, ATP1A2, FXYD2, ATP2B2, BAX, BCL2, BMP4, TSPO, CACNA1B, CACNA2D1, CACNB4, CALM3, CAMK2A, CAMK2G, CD4, CD63, CCR1, CYBA, DIAPH1, EDNRA, STOM, F2R, GCG, FFAR1, GSTM2, HRC, ICAM1, IGF1, IL13, NTSR1, P2RX3, P2RX4, P2RX7, PAWR, PDE4B, PDE4D, PDPK1, PER1, PIK3C2A, PIK3CG, FXYD3, PLN, PRKACA, PRKCE, PRKD1, PRSS8, PTPN3, PTPN6, RCVRN, RYR2, S100A1, SCN2B, SCN4B, SCN5A, SCNN1B, XCL1, SEMG1, SGK1, SLC8A1, SLC9A1, SLC9A3, SLN, SNCA, SNTA1, SPINK1, STC1, TRPC1, TRPC3, TRPC4, UCN, WFS1, YWHAH, SLC30A1, ZP3, CD84, HAP1, RGN, SLC9A3R1, GSTO1, ATG5, SGK2, TRDN, CREB3, CLDN16, AHCYL1, CORO1A |
1589 | GO:0044282 | 0.00 | 2.55 | 76.63 | 118 | 184 | small molecule catabolic process | ABAT, ACAA1, ACADL, ACADM, ACADS, ACADSB, ACADVL, ACAT1, ACOX1, ADH5, AGXT, AKT2, ABCD1, ALDH9A1, ALDOB, ALDOC, AMT, ARG1, ASL, ASPA, ALDH7A1, AUH, BAD, BCAT1, BCAT2, BCKDHA, CBS, CCBL1, CDO1, CNR1, CPT1B, CPT2, CRYM, SLC25A10, CTH, DAO, DECR1, DLD, ECH1, EHHADH, ENO2, ESD, ETFA, ETFDH, FAAH, FUT6, FUT8, GAD1, GAD2, GALE, GALK1, GAPDH, GLB1, GLS, GLUD1, GLUD2, GLUL, GOT1, GOT2, GPT, GSTZ1, HSD17B10, HADHA, HAL, HK2, HMGCL, HPD, HSD17B4, IDUA, IDO1, IVD, KHK, LDHA, LIPE, ALDH6A1, NUDT1, OAT, OGDH, OTC, OXCT1, PAH, PCCA, PFKFB2, PFKFB4, PGAM2, PGK1, PGM1, PPP2R5D, ABCD3, QDPR, RPE, SCP2, SHMT1, SUOX, SULT2A1, TAT, TST, TWIST1, ACOX2, ACOX3, BBOX1, DDO, CYP4F2, ALDH4A1, KYNU, XYLB, ACOT8, AASS, BCKDK, AKR1A1, ECI2, SLC25A17, FUT9, ALDH1L1, SDS, SLC27A4, SLC27A2, ACOT7 |
1590 | GO:0006909 | 0.01 | 2.55 | 11.60 | 18 | 28 | phagocytosis | ABL2, ADORA1, ADORA2A, ANXA1, ANXA3, ANXA11, CD14, CEBPE, CRP, P2RX7, SLAMF1, ICAM5, RAB7A, SRPX, RUBCN, SPON2, CORO1A, TUSC2 |
1591 | GO:0046683 | 0.01 | 2.55 | 11.60 | 18 | 28 | response to organophosphorus | DGKQ, LPAR1, IL1B, KCNJ11, P2RX3, P2RX4, P2RX7, P2RY11, RFC3, RYR3, SELL, SLC6A4, SOD1, TRPC3, TYMS, TRPV1, CIB2, TRIM16 |
1592 | GO:0035690 | 0.01 | 2.55 | 12.94 | 20 | 31 | cellular response to drug | CD69, DDC, DPEP1, GAS6, GPLD1, HIF1A, IL1B, KCNQ1, PDE4A, PDE4B, QDPR, RAP1A, RAP2A, REST, EIF2B5, EFTUD2, KCNE2, RAPGEF3, CERS1, CHEK2 |
1593 | GO:0010942 | 0.00 | 2.55 | 127.30 | 195 | 306 | positive regulation of cell death | ADRB2, AES, AGTR2, ALDH1A3, ALOX12, BIN1, ANXA1, ANXA5, APBB1, APC, ARHGAP4, ATF3, BARD1, BCL2, BCL2A1, BCL2L1, BID, BIK, BMP4, BNIP3, BNIP3L, BOK, BTG1, BUB1, TSPO, C1QBP, CAMK2A, CASP8, CCK, CD14, TNFRSF8, CD40, CDK4, CDKN1A, CDKN2A, CNR1, COL4A3, CRYBA1, CTGF, CTLA4, CTNNA1, CYLD, GADD45A, DDX3X, DFFA, DFNA5, DHODH, DNM2, DNMT3A, DUSP1, ECT2, LPAR1, EEF1A2, EIF2S1, ERCC3, F2R, F3, FAP, FGD1, B4GALT1, SFN, GPLD1, GRIN2A, HBA1, HBA2, HIF1A, HIP1, HMGCR, HP, HRG, PRMT2, IFNG, IGF2R, IGFBP3, IL1B, IL10, IDO1, ING2, ITGA6, IRF5, ITGB1, KCNK2, KNG1, LDHA, SMAD3, MAL, SLC11A2, NTRK1, NTRK3, NTSR1, P2RX7, PPID, PPP1CA, PPP2R1A, PPP2R1B, PPP3R1, PRKCI, MAPK8, EIF2AK2, PTGIS, PTN, RAC1, RARB, REST, RPS3, RPS6, RPS6KA2, RPS27A, RXRA, SORT1, S100A8, S100A9, S100B, SFPQ, SFRP4, ITSN1, SIAH1, SLC9A1, SMPD1, SIGLEC1, SNCA, SOD1, SOS1, SOS2, SOX4, TOP2A, TP73, TPD52L1, TRAF2, TRIO, TRPS1, UBB, VAV1, VDR, TRPV1, WNT11, YWHAG, YWHAH, YWHAZ, FOSL1, SRPX, NSMAF, KLF11, PRKRA, TP63, UNC5C, AKR1C3, DYNLL1, PEA15, TRADD, RIPK1, CRADD, HRK, TNFSF12, TNFSF10, RIPK2, TNFRSF10B, TNFRSF10A, CFLAR, TSC22D1, ALDH1A2, ARHGEF7, BCL10, KALRN, LATS1, ARHGEF2, STK17B, STK17A, SLIT2, SLC9A3R1, EIF2AK3, ARHGEF6, RAPGEF2, RASSF2, BCLAF1, ARHGEF17, TNFSF15, CASP8AP2, HDAC6, PDCD6, BCL2L10, SAP18, KATNB1, VAV3, ATG7, ARL6IP5, SIVA1, RBCK1, TXNIP, RRAGA, RNPS1, SERINC3, CAPN10, CHEK2, AKAP13 |
1594 | GO:0015980 | 0.00 | 2.54 | 41.41 | 64 | 100 | energy derivation by oxidation of organic compounds | ACADVL, ACO1, ADSL, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, BAX, BNIP3, CAT, COX4I1, COX5B, COX6A1, COX6B1, COX7B, COX7C, COX8A, COX15, CYP1A2, DLD, ETFA, ETFDH, BLOC1S1, GPD1, HIF1A, IDH1, IDH3A, LDHA, MDH1, MDH2, OGDH, OXA1L, SDHB, SDHC, SDHD, SNCA, SURF1, TAZ, UCN, UCP1, UQCRB, UQCRC1, UQCRC2, UQCRFS1, UQCRH, SUCLG2, SUCLG1, SUCLA2, SLC25A14, COX7A2L, COX5A, ATP5J2, TRAP1, SLC25A13, COQ7, ATP5H, ATP5L, UQCR11 |
1595 | GO:0010033 | 0.00 | 2.53 | 18.46 | 30 | 51 | response to organic substance | ACP2, ALB, AMPD1, ATRX, DAGLA, COL6A2, ENSA, ERCC1, GLUL, GPX3, GYS2, KCNA5, PFKFB2, S100P, SEL1L, SGTA, SLC6A12, SQLE, RNF103, FZD5, BCL10, USP13, USP14, GPR55, MARCH6, ERLIN1, USP19, MALT1, OS9, ERLIN2 |
1596 | GO:0045931 | 0.00 | 2.53 | 17.49 | 27 | 42 | positive regulation of mitotic cell cycle | ANXA1, ASNS, CCND1, BRCA2, CCNB1, CDC6, CDK4, DDX3X, EIF4E, EIF4EBP1, HES1, KCNA5, MAD2L1, PBX1, PRKCA, RAD51B, RDX, SMARCD3, STAT5B, TAL1, UBE2E2, CDC45, CUL4B, CUL4A, RAB11A, PHOX2B, USP2 |
1597 | GO:1901606 | 0.00 | 2.53 | 23.35 | 36 | 56 | alpha-amino acid catabolic process | ARG1, ASL, ASPA, ALDH7A1, AUH, BCAT2, CCBL1, CRYM, DLD, GAD1, GAD2, GLS, GLUD1, GLUD2, GLUL, GOT1, GOT2, GPT, GSTZ1, HAL, HMGCL, HPD, IDO1, IVD, ALDH6A1, OAT, OGDH, OTC, PAH, QDPR, TAT, DDO, ALDH4A1, KYNU, AASS, ALDH1L1 |
1598 | GO:0044281 | 0.00 | 2.53 | 231.69 | 355 | 582 | small molecule metabolic process | AARS, ABCB7, ACO1, ACP5, ACY1, ADRA2C, ALAD, ALAS1, ALAS2, ALB, ALDH3A1, ANGPT1, SLC25A4, AOC2, APC, ARF1, ARG2, ARL2, ARSA, STS, ARSD, ARSE, ARSF, BLVRA, BLVRB, BMP1, BNIP2, BSG, BTD, C3, DAGLA, CA1, CA2, CA4, CA5A, CA6, CA7, CACNA1E, SLC25A20, CD36, CD44, CHRM3, CKM, CLPS, COMT, COX5B, COX6A1, COX6B1, COX7B, COX7C, CPOX, CSNK1G2, CTGF, CYP1A2, CYP2A6, CYP2A13, CYP2F1, CYP3A5, DARS, DBH, DDC, DIO1, DIO2, DIO3, SARDH, DNM2, DPEP1, EPRS, EXT1, EXT2, EXTL1, EXTL2, EXTL3, FABP2, FABP6, FABP7, ACSL1, ACSL4, FAU, GPC4, GPC5, FMO3, KDSR, GALC, GALNS, GATA3, GHSR, GIF, GPC3, GM2A, GNB1, GNB2, GPC1, FFAR1, GSS, GSTM1, GSTM2, HARS, HAS1, HAS3, HBA1, HBA2, HEXA, HEXB, HLCS, HMBS, HPN, HSD11B1, HSP90AA1, IDH3A, IDS, ITPR1, ITPR2, ITPR3, KCNS3, KPNB1, LUM, CHST6, NUBP1, RPL10A, NUP88, NUP98, OAZ1, OAZ2, ODC1, OMD, OGN, P4HA1, PAM, PEPD, ATP8B1, ABCB1, PIK3C2A, PIK3C2B, PIK3C3, PIK3CB, PIK3CG, PI4KA, PI4KB, PIP4K2A, PPT1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKD1, MAPK3, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, QARS, RAN, RAP1A, RBP2, RHAG, RLBP1, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS28, RPS29, SAT1, SDC1, SDC2, SDC4, SDHB, SDHD, SGSH, SI, ST6GAL1, SLC2A2, SLC2A4, SLC2A5, SLC4A1, SLC5A5, SLC6A6, SLC6A8, SLC7A4, SLC9A1, SLC10A1, SLC10A2, SLC16A1, SLCO1A2, SLC22A1, SLC22A3, SLC22A2, SLC22A5, SMARCD3, SMS, SNAP25, SP1, SRD5A1, STAT5B, STXBP1, ABCC8, TARS, TBL1X, TNFRSF1A, TPMT, TYRP1, UCP1, UQCRFS1, LRP8, PAX8, AIMP2, NUP214, SLC25A16, AAAS, SLC7A5, PIP5K1B, PIK3R3, AGPS, PDXK, AOC3, B4GALT4, B4GALT3, ABCC3, PEX11A, SUCLG2, CES2, IQGAP1, GGH, HDAC3, VNN2, VNN1, SGPL1, SLC5A6, CPNE1, MGAM, P4HA2, SLC25A14, RPL14, COX7A2L, VAPB, VAPA, B4GALT6, B4GALT5, RPL23, CPNE6, GRHPR, LIPG, CIAO1, ABCG2, EIF2AK3, CHST3, PSMF1, NUP155, HS2ST1, SDC3, NUP93, PTDSS1, SPOCK2, PSMD6, FIG4, HS3ST4, HS3ST3B1, HS3ST3A1, HS3ST1, GNE, ABCC5, GPC6, COL4A3BP, NUBP2, SLC25A15, PSME3, GLYAT, B3GNT3, ST3GAL6, SEC24B, SEC23A, CRTAP, CARM1, ATG7, PRDX4, AGPAT2, SLCO1B1, PDPN, FARS2, CERS1, NUP50, SEC24A, SERINC3, ACOT2, UQCR11, SLC35D2, RAPGEF4, KERA, NUPL2, RPP14, TREH, INMT, RPL35, CA5B, B4GALT7, LYPLA2, CTRC |
1599 | GO:0048812 | 0.00 | 2.53 | 179.34 | 273 | 432 | neuron projection morphogenesis | ACTB, ACTG1, ADAM10, ADCY1, AP2A1, AP2B1, ANGPT1, APBB1, APC, ARHGAP4, ATOH1, BCL2, BMPR2, CACNA1S, CACNB4, CALM3, CAMK2A, CAMK2G, CCK, CD72, CDC42, CHN1, AP2M1, AP2S1, CLU, CLTA, CNP, COL2A1, COL3A1, COL4A3, COL4A4, COL4A5, COL5A1, COL5A2, COL6A2, COL6A3, COL9A1, COL9A3, CSF2, CSF2RB, CSNK2A1, CSNK2A2, DCC, DLG1, DLG3, DLX5, DNM1, DNM2, DPYSL3, HBEGF, ECM2, DUSP5, DUSP7, DUSP9, EFNA3, EFNA4, EFNA5, EFNB2, EGR2, EPHA2, EMX1, CTTN, EPHA1, EPHA3, EPHA5, EPHA7, EPHA8, ERBB2, EREG, ETV1, ETV4, EXT1, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, GAP43, GATA3, GDI1, GDNF, GFRA1, GOLGA4, GPC1, GPM6A, GRB2, GRIN2A, ARHGAP35, NRG1, HSPA8, HSP90AA1, HSP90AB1, IL2RA, IL2RB, IL2RG, ISL1, ITGA1, ITGA2, ITGA5, ITGA9, ITGAV, KIF5A, KIT, KRAS, ABLIM1, LIMK1, MARK3, RAB8A, KITLG, NRAS, NRCAM, NRTN, NTF3, NTF4, NTRK1, NTRK2, NTRK3, NTN3, OGN, OPHN1, OTX2, PEBP1, PARK2, PAX2, PPP5C, PRKCQ, PRKCZ, MAPK3, PSPN, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPRA, PTPRM, RAB3A, RAC2, RAF1, RASA2, RNF6, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RRAS, RYK, S100A6, S100B, SCN5A, SDCBP, SEMA3F, ITSN1, SHC1, SHH, SIAH1, SIAH2, SLIT1, SLIT3, SOS1, SOS2, SPAST, SPTA1, SPTB, SRF, AURKA, STXBP1, SYT1, SYT4, CNTN2, TBCE, DYNLT1, TNR, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, UGT8, VCL, VEGFA, EZR, WEE1, XK, SEMA3B, FZD3, FGF23, RND2, USP9X, CUL3, SEMA7A, CNTNAP1, UNC5C, NUMB, PEA15, RAB11A, IQGAP1, NRP2, ARHGEF7, CPNE1, PHOX2B, RPS6KA4, KALRN, RPS6KA5, SLIT2, CPNE6, NRXN3, NRXN1, PSMF1, AATK, FEZ2, RIMS2, SEMA3E, IST1, FARP2, PSMD6, RBX1, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, PSME3, SPON2, OLFM1, VAV3, SLC9A6, CAP2, CAP1, STK25, SEMA6C, SEMA6B, SEMA4F, SEMA4B, ATG7, ARPC1A, DPYSL4, TBR1, CHL1, FRS3, VAX1, TWF2 |
1600 | GO:0043255 | 0.00 | 2.52 | 17.53 | 27 | 42 | regulation of carbohydrate biosynthetic process | ADCYAP1R1, AP2A1, AKT2, CLTC, GCG, KAT2A, HAS2, HRH1, IGF1, IGF2, INS, NTSR1, P2RY1, ENPP1, PPP1CA, PTAFR, PTGER4, PTH1R, RANBP2, SNCA, DYRK2, OGT, KAT2B, NR1D1, EPM2AIP1, SORBS1, ARPP19 |
1601 | GO:0002200 | 0.01 | 2.52 | 11.69 | 18 | 28 | somatic diversification of immune receptors | ADAR, ATM, CD28, CD40, ERCC1, IFNG, IL10, RAG1, RAG2, TNFSF4, UNG, WHSC1, TNFSF13, RNF8, EXO1, IL27RA, VPRBP, BATF |
1602 | GO:0006195 | 0.01 | 2.52 | 11.69 | 18 | 28 | purine nucleotide catabolic process | ADA, CAT, GPX1, HPRT1, NUDT1, OGG1, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, PDE5A, RAPGEF3, PDE10A |
1603 | GO:0060711 | 0.01 | 2.52 | 11.69 | 18 | 28 | labyrinthine layer development | CASP8, CDX2, CDX4, GJB5, GRB2, HES1, RBPJ, IL10, ITGA4, JUNB, LLGL2, CITED1, SPINT1, ST14, WNT2, FZD5, SOCS3, SPINT2 |
1604 | GO:0007612 | 0.00 | 2.52 | 16.22 | 25 | 39 | learning | AMPH, ARF4, BCHE, COMT, CTNND2, FYN, JUN, NTRK2, NTSR1, PARK2, PRKAR2B, PTGS1, PTN, SLC8A3, TACR2, CNTN2, EPM2A, FOSL1, AAAS, DGKI, GPR52, NRXN3, NRXN1, NRXN2, ATP8A1 |
1605 | GO:1901652 | 0.04 | 2.52 | 7.70 | 12 | 19 | response to peptide | AVPR1B, AVPR2, CASP4, IRF5, KLF10, TNFAIP3, RIPK2, IL1RL1, ARHGEF2, KLF4, KLF2, KLF1 |
1606 | GO:0051347 | 0.00 | 2.52 | 171.94 | 261 | 412 | positive regulation of transferase activity | ACVR2B, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADORA1, ADRA2C, ADRB2, ALK, ANG, ANGPT1, BAD, BAX, CCND1, BMI1, BMP4, C5, CALM3, CAMK2A, CAMK2G, CCNB1, CCNC, CCND3, CCNH, CCNT1, CCNT2, CD4, CD40, CD74, CDC6, CDC20, CDC27, CDC42, CDK5, CDKN1A, CENPE, CHI3L1, CLU, CSF2, CSF2RB, CSPG4, ACE, GADD45A, DLG1, HBEGF, DUSP5, DUSP7, DUSP9, ECT2, LPAR1, EDN3, EEF1A2, EFNA1, EFNA5, EMP2, EPHA4, EPHA8, ERBB2, EREG, ERCC6, ERN1, F2R, ACSL1, FCER1A, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FGR, FLT1, FLT3, FPR1, FYN, GAS6, GCG, GRB2, RAPGEF1, GRIN2A, GRM1, HGF, NRG1, HSP90AB1, IGF2, IL1B, IL2RA, IL2RB, IL2RG, ILK, INS, IRAK1, IRAK2, ITGA1, KIT, KRAS, LTF, MARK3, MAP3K5, KITLG, MAP3K11, NRAS, NTF3, NTRK1, NTRK3, DDR2, NVL, P2RX7, PEBP1, PDE6G, PDE6H, PDPK1, PFKFB2, PIK3CB, PIM1, PIK3CG, PPP5C, PRKAA1, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCQ, PRKCZ, MAPK3, EIF2AK2, PROX1, RELN, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN1, PTPRA, RAC1, RAF1, RAP1A, RASA2, RPS2, RPS3, RPS27A, S100A12, CCL21, SDC4, SHC1, STIL, SKP1, SLC11A1, SNCA, SOD1, SORL1, SOS1, SPTA1, SPTB, STK10, STK11, SYK, TP73, TPD52L1, TRAF2, UBB, UBE2D1, UBE2L3, UCN, VEGFA, WNT11, ZNF16, ZP3, LRP8, FZD5, ARHGEF5, FGF23, FZD4, FZD8, CUL3, CUL1, IKBKG, CAMK1, MAPKAPK5, CDC14B, MADD, TNFSF11, PDE5A, TNKS, PEA15, CDC23, RIPK1, ADAM9, RIPK2, TNFRSF10B, TNFRSF10A, IQGAP1, CDC16, CDK5R2, AURKB, VAPB, ITGB1BP1, S1PR2, KLF4, TAOK2, PSMF1, CARTPT, TRAF4, RAPGEF2, SLK, RASSF2, ZEB2, EPM2AIP1, PSMD6, OXSR1, TNFSF15, RBX1, ABI1, TOM1L1, RAD50, AKAP9, RASA4, PSME3, ANAPC10, VAV3, STK25, CCT4, CCT2, NRG3, FRS3, MALT1, JTB, COPS8, ERP29, UBE2C, MAP4K5, FZD10, DUSP12 |
1607 | GO:1901565 | 0.00 | 2.52 | 92.23 | 141 | 221 | organonitrogen compound catabolic process | ABAT, ACADL, ACADSB, ACAT1, ADA, AGXT, ALDH9A1, AMBP, AMT, ANPEP, AOX1, ARG1, ASL, ASPA, ALDH7A1, AUH, BCAT1, BCAT2, BCKDHA, BHMT, BLVRA, BLVRB, CAT, CBS, CCBL1, SCARB1, CD44, CDA, CDO1, TPP1, COMT, CRYM, VCAN, CSPG4, SLC25A10, CTH, CYP3A4, CYP3A5, DAO, DBH, DCN, ACE, DHPS, DIO3, DLD, DPYD, DUT, TYMP, ENPEP, GPC4, GPC5, GAD1, GAD2, GALC, GALNS, GPC3, GLB1, GLS, GLUD1, GLUD2, GLUL, GM2A, GOT1, GOT2, GPC1, GPT, GPX1, GSTZ1, HSD17B10, HAL, HEXA, HEXB, HMGCL, HPD, HPRT1, IDE, IDS, IDUA, IDO1, IVD, LTA4H, LUM, ALDH6A1, NUDT1, NTHL1, OAT, OMD, OGDH, OGG1, OGN, OTC, OVGP1, PAH, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, ENPP2, PPT1, QDPR, RNPEP, SAT1, SDC1, SDC2, SDC4, SGSH, SHMT1, SLC9A1, SMPD1, SUOX, TAT, TST, UNG, UPP1, XPNPEP1, BBOX1, DDO, PDE5A, ALDH4A1, SGPL1, MBD4, KYNU, PGLYRP1, ENTPD4, SDC3, GPC6, AASS, BCKDK, RAPGEF3, CSPG5, ALDH1L1, PDE10A, SMPDL3A, SDS, KERA, ADAMTS13 |
1608 | GO:0048738 | 0.00 | 2.52 | 32.52 | 50 | 78 | cardiac muscle tissue development | ACVR1, AGTR2, BMP4, CCNB1, CDC42, COL11A1, DSP, S1PR1, EFNB2, GATA4, GATA6, KAT2A, GJA5, NRG1, RBPJ, ISL1, ITGB1, SMAD1, SMAD7, PLN, PRKAR1A, PROX1, RARA, RARB, RXRA, RYR2, SGCB, SGCD, SLC8A1, SLC9A1, SRF, TAZ, TNNC1, TNNI3, TNNT2, TSC1, COL14A1, VEGFA, WNT2, CSRP3, IFT88, SORBS2, ALDH1A2, HAND1, AKAP6, ATG5, SPEG, ATG7, PDLIM5, BVES |
1609 | GO:0009179 | 0.00 | 2.51 | 22.12 | 34 | 53 | purine ribonucleoside diphosphate metabolic process | AK2, AK4, ALDOB, ALDOC, ARNT, BAD, BPGM, ENTPD2, DLG1, DLG2, DLG3, ENO2, GAPDH, GPD1, GUK1, HIF1A, HK2, IGF1, INS, LDHA, OGDH, P2RX7, PFKFB2, PFKFB4, PGAM2, PGK1, PGK2, PGM1, PPP2R5D, PRKAA1, STAT3, OGT, HDAC4, ECD |
1610 | GO:0006721 | 0.00 | 2.51 | 26.71 | 41 | 64 | terpenoid metabolic process | ABCA4, ADH5, ALDH1A1, ALDH1A3, ALDH3A2, APOA1, APOA4, APOC2, OPN1SW, AKR1C4, CLPS, CYP1A2, CYP3A4, FDFT1, FDPS, GPC4, GPC5, OPN1MW, GPC3, GPC1, IL1B, PDE3A, RBP1, RBP2, OPN1LW, RLBP1, SDC1, SDC2, SDC4, SLC12A1, SRD5A1, STAR, LRP8, AKR1C3, DGAT1, ALDH1A2, DHRS3, GGPS1, SDC3, GPC6, DHRS9 |
1611 | GO:0051238 | 0.00 | 2.50 | 31.30 | 48 | 75 | sequestering of metal ion | ATP1A2, ATP7B, BAX, CALM3, CASQ2, CCR5, CYBA, DIAPH1, EDNRA, F2R, XCR1, GSTM2, HRC, HTR2C, IL13, ITPR1, ITPR2, ITPR3, NTSR1, P2RX7, PDE4D, PDPK1, PLN, PRKACA, PRKCE, PRKD1, PTPN6, RYR1, RYR2, RYR3, S100A8, S100A9, CCL21, XCL1, SLC8A1, SNCA, TRPC1, TRPV1, SLC30A1, SLC30A2, AP3D1, HAP1, GSTO1, AKAP6, ATG5, TRDN, CHERP, CORO1A |
1612 | GO:0051170 | 0.00 | 2.50 | 63.43 | 97 | 152 | nuclear import | ADAR, AGTR2, ANGPT1, ARNTL, RERE, BCL3, BMP4, BMP6, BMPR1A, BRCA1, CBLB, CD36, CDH1, CDKN1A, CYLD, DAB2, ECT2, EDA, EMD, F2R, FGF9, FLNA, FYB, GAS6, GNAQ, HCLS1, HES1, HSP90AB1, IFNG, IGF1, IL1B, IL10, IL18, JUN, JUP, KPNA1, KPNB1, KPNA4, KPNA5, TNPO1, IPO5, SMAD3, TONSL, NUP88, NUP98, OGG1, OR1D2, PPM1A, PPM1B, PPP3R1, PRKCQ, MAPK3, RAN, RANBP2, SFRP5, SHH, SIX3, SLC9A1, SLC11A1, SNAI2, STAT3, SYK, TRIP6, TRPS1, TSC2, ZIC1, NUP214, AKAP1, FZD7, DYRK2, AKR1C3, TNFSF14, IL18R1, HDAC3, RPL23, SLC9A3R1, ZFYVE9, AKAP6, CABP1, LITAF, NUP155, IPO13, NUP93, CEP57, TRIM28, NUTF2, APC2, TACC3, CREB3, CHERP, RBCK1, TXNIP, SIX2, EDAR, SEC61B, RBPMS, PHB2 |
1613 | GO:0034614 | 0.02 | 2.50 | 10.40 | 16 | 25 | cellular response to reactive oxygen species | APOA4, CD36, DHFR, DNM2, DPEP1, FANCC, GUCY1B3, SLC8A1, SOD1, SOD2, PRDX2, TRAF2, AKR1C3, RGN, FBLN5, PRDX3 |
1614 | GO:0071900 | 0.00 | 2.50 | 65.14 | 100 | 158 | regulation of protein serine/threonine kinase activity | ADORA1, ANGPT1, BMP4, CAMK2A, CAMK2G, CAV3, CSF2, CSF2RB, HBEGF, DUSP1, DUSP4, EREG, F2R, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FYN, GPS2, GRB2, RAPGEF1, GRIN2A, NRG1, HMGCR, HSPB1, IGF1R, IL2RA, IL2RB, IL2RG, MARK3, NRAS, NTRK1, PEBP1, PPP2R1A, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, EIF2AK2, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN6, PTPRA, PTPRJ, RAF1, RAP1A, RASA2, RGS2, SERPINB3, SMPD1, SORL1, SOS1, SPTA1, SPTB, TSG101, UVRAG, YWHAG, FGF23, ADAM9, TAOK2, PSMF1, CARTPT, PSMD6, RBX1, AKAP9, RASA4, PSME3, TRIB1, RGS14, FRS3, STK38 |
1615 | GO:0048524 | 0.00 | 2.50 | 20.85 | 32 | 50 | positive regulation of viral process | ADAR, ADARB1, CCNH, CCNT1, CD28, CDK9, CHD1, DDB1, DDX3X, EP300, ERCC3, GTF2F1, HPN, IFIT1, JUN, PPID, SMARCA4, SP1, SRPK2, SSRP1, STAU1, SUPT4H1, TARBP2, TMPRSS2, TOP2A, TSG101, RAB7A, CTDP1, PPIE, PPIH, TRIM38, SUPT16H |
1616 | GO:0008283 | 0.00 | 2.50 | 74.85 | 117 | 192 | cell proliferation | ACHE, ACVR2A, ADRA1B, ALK, AMBN, BIN1, APOA1, BCAT1, TNFRSF17, BOK, ZFP36L2, BST2, BUB1, BUB1B, BYSL, CD5, TNFSF8, SCARB1, CD70, CDC25C, CDC27, CDK3, CDK5, CDK9, CENPF, CHRM3, CHUK, CKS1B, CSPG4, DAB2, DMBT1, DTYMK, E4F1, EEF2, EPHA2, ELN, EMP1, ENPEP, EPS8, EPS15, ERCC1, ERG, ERN1, GPC4, GCG, KAT2A, NR6A1, GNAT1, GNB1, HDGF, HLCS, IFI16, IL15RA, INSIG1, INSL4, IRF2, ISG20, ITPKB, KRT2, KRT16, LIPA, MKI67, MAP3K11, CITED1, PA2G4, PAX1, PENK, PIK3CB, PIM1, PPP1R8, PRKX, PYY, RAC1, REG1B, RPL23A, RPS6KA1, RPS27, SETMAR, STIL, SIPA1, SP2, STAT4, TSPY1, TYMS, UBE2L3, UBE2V2, MIA, PICALM, FOXN1, BLZF1, CDC14A, PDXK, CREG1, CDC16, EIF2S2, USP13, AURKB, LIPG, BCAR1, DLGAP5, GINS1, SETDB1, SRA1, COL4A3BP, TSPAN1, TRAIP, APC2, CITED2, RAPGEF3, PDPN, KHDRBS1, YME1L1, ZMYND11, ASCC3, CD160, ECD, TUSC2 |
1617 | GO:0009144 | 0.00 | 2.49 | 34.59 | 53 | 83 | purine nucleoside triphosphate metabolic process | ADA, AK2, AK4, ALDOB, ALDOC, AMPD2, ARNT, ATP1A2, ATP6V1A, ATP6V1B1, ATP6V1B2, BAD, BPGM, TSPO, COX4I1, COX8A, COX15, CTNS, DLD, ENO2, GAPDH, GNAI3, GPD1, GUK1, HIF1A, HK2, HSPA8, IGF1, INS, LDHA, NUDT1, OGDH, P2RX7, PFKFB2, PFKFB4, PGAM2, PGK1, PGK2, PGM1, PPP2R5D, PRKAA1, SDHC, SNCA, TAZ, UQCRB, UQCRC1, UQCRC2, UQCRH, OGT, COX5A, HDAC4, COQ7, ECD |
1618 | GO:0048708 | 0.02 | 2.49 | 10.42 | 16 | 25 | astrocyte differentiation | ABL2, BIN1, EPHA4, FGFR3, HMBS, HES1, IL1B, NTRK3, MAPK3, S100B, SHH, SOX9, STAT3, TAL1, CNTN2, NR2E1 |
1619 | GO:0032880 | 0.00 | 2.49 | 99.45 | 152 | 241 | regulation of protein localization | ABAT, ABL2, ACHE, ADRA2C, ALOX15B, ANG, SLC25A4, ANXA1, ANXA4, ANXA5, APBB1, APOA1, ARF1, ARHGDIG, ARL2, ARNTL, BLK, C5, CACNA1A, CACNA1E, CASP5, CD2, CD14, CD38, CD40, CD58, CFTR, CHRM3, CNR1, CRP, EFNA5, CELSR2, ENSA, EPHA5, F2R, F2RL1, FBLN1, FCN1, FGA, FGG, FGR, GATA3, GCG, GHSR, GIP, GJA5, GLP1R, GLUD1, GLUL, GNAS, GPLD1, GPR27, FFAR1, HIF1A, HMGCR, FOXA2, DNAJB2, HSPA8, IFNA2, IL1A, IL13, TNFRSF9, ISL1, ITPR1, ITPR2, ITPR3, KCNA5, KCNJ11, KCNN4, KCNS3, LLGL2, RAB8A, SEPT2, OXCT1, P2RX7, PAEP, PAM, PCSK1, CDK16, PDE3B, PDE4C, SLC26A4, PFKFB2, PIK3C3, PPID, SRGN, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCE, PRKCZ, PTCH1, PTGER4, RAP1A, REST, RFX3, CX3CL1, SIX1, SLC2A2, SLC16A1, SNAP25, STXBP1, ABCC8, SYK, TRAF2, TRH, TRPM2, TSG101, TWIST1, TNFSF4, TNFRSF4, SUMO1, NR1H2, VEGFC, VIP, VSNL1, WHSC1, ARHGEF5, PICALM, NR0B2, STX10, ADAM9, RAB11A, IQGAP1, SYT7, IL1RL1, HMGN3, RAB9A, ATG5, STXBP5L, NR1D1, CLOCK, CARTPT, KIAA0586, SPCS2, C2CD2L, RABGAP1L, NR1H4, HDAC6, TRIM22, TRIM16, SEC24A, ERP29, WWP2, RAPGEF4, CAPN10, GLMN |
1620 | GO:0006873 | 0.00 | 2.49 | 123.11 | 187 | 295 | cellular ion homeostasis | ABCB7, ABL2, ACO1, ADCYAP1R1, ADRA1B, AGTR2, ALAS2, ANXA6, APLP2, ARF1, ATP1A2, ATP12A, ATP1B3, ATP2A1, ATP2B1, ATP2B2, ATP4A, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, ATP7B, AVP, AVPR1B, BAX, BCL2, BDKRB2, BMP4, BMP6, CA2, CA7, CACNA1A, CACNA1F, CACNB4, CALCR, CALM3, CASQ2, CAV3, CD4, CD36, CD38, CD40, CD52, CFTR, CLCN3, CLN5, CCR1, CCR3, CCR5, CCR8, CP, CYBA, CD55, DIAPH1, S1PR1, LPAR1, S1PR3, EDN2, EDN3, EDNRA, EDNRB, ESR1, F2R, F2RL1, FTL, GALR1, GLP1R, GNA15, GNAT2, GNB1, CCR10, XCR1, GRINA, GRM1, GSTM2, GTF2I, HEXB, HIF1A, HPX, HRC, HTR2C, IL1B, IL13, IREB2, ITGB1, ITPR1, ITPR2, ITPR3, KCNA5, KCNJ2, KCNK3, KISS1, KNG1, LTF, NUBP1, SLC11A2, NTSR1, OXT, P2RX3, P2RX4, P2RX7, P2RY1, P2RY2, P2RY4, PDE4D, ENPP1, PDPK1, SLC26A4, PIK3CB, PIK3CG, PLN, PPT1, PRKACA, PRKCA, PRKCB, PRKCE, PRKD1, PTH1R, PTPN6, PYGM, RAP1GDS1, RHAG, RYR1, RYR2, RYR3, S100A8, S100A9, CCL21, XCL1, SGK1, SLC4A1, SLC8A1, SLC8A3, SLC9A1, SLC11A1, SNCA, SOD1, STC1, TAC1, TNNI3, TPT1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, VDR, TRPV1, WFS1, XK, SLC30A1, SLC30A2, RAB7A, CSRP3, FGF23, S1PR4, INPP4B, AP3D1, ATP6V0E1, HAP1, RGN, ATP6V0D1, SLC24A1, XPR1, VAPB, ATP6V1F, SLC9A3R1, ABCG2, GSTO1, AKAP6, ATG5, ATP6V1G1, HEPH, ABCB6, SGK2, TRDN, CIB2, CHERP, CXCL13, SLC34A2, SCGN, CLDN16, CCR9, SLC26A1, CORO1A |
1621 | GO:0006928 | 0.00 | 2.49 | 276.35 | 417 | 681 | movement of cell or subcellular component | ACTB, ACTG1, ADCY3, AP2A1, AP2B1, ANG, APOA1, SHROOM2, ARF4, ARF6, ASTN1, RERE, ATOH1, ATP1B3, KIF1A, AXL, BAX, BICD1, DST, BSG, BTG1, TSPO, CACNA1E, CACNA1S, CACNB4, CALM3, CAMK2A, CAMK2G, CAPZA1, CAPZB, CAV3, CCK, CD2, CD9, CD44, CD48, CD58, CD72, ADGRE5, CD151, CDC42, CENPE, CHN1, AP2M1, AP2S1, AP3S1, CLTA, CCR5, LTB4R, COL2A1, COL4A3, COL4A4, COL4A5, COL5A1, COL5A2, COL6A2, COL6A3, COL9A1, COL9A3, CSF2, CSF2RB, CSNK2A1, CSNK2A2, VCAN, CSPG4, CTGF, CTNNA2, CXADR, DBH, DCC, DCX, DLG1, DLG3, DLX5, DNM1, DNAH5, DNAH8, DYNC1H1, DYNC1I1, DYNC1I2, DPP4, DUSP5, DUSP7, DUSP9, EDNRB, EFNA3, EFNA4, EFNA5, EFNB2, CELSR2, EGR2, EGR3, CTTN, EMX2, ENPEP, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPS8, ERBB2, EREG, ERG, ETV1, ETV4, EXT1, FAP, FCER1G, FGF3, FGF6, FGF8, FGF9, FGFR3, FGFR4, FPR1, FPR2, FPR3, FUT8, FYN, GAP43, GAS8, BLOC1S1, GDNF, GFRA1, GPC1, GPM6A, GPR15, GPX1, GRB2, GRIN2A, ARHGAP35, HIST1H1T, HCK, HEXB, NR4A1, HRH1, HES1, HSPA8, HSP90AA1, HSP90AB1, IL2RA, IL2RB, IL2RG, IL10, IL13, ING2, ITGA6, ISL1, ITGA1, ITGA7, ITGA9, ITGAL, ITGAM, ITGAX, ITGB4, KCNA5, KCNE1, KCNQ1, KIF5A, KLC1, KIF25, KPNB1, KRAS, KRT2, LDHC, ABLIM1, LIMK1, LSP1, MARK3, SMCP, MYO1B, NRAS, NRCAM, NRTN, NTRK1, NTRK2, NTN3, OGDH, OLR1, OPA1, OPHN1, OR1D2, OTX2, P2RY1, PEBP1, PCM1, PEX14, PGK2, PIK3C2A, PIK3C2B, PIK3CB, PIK3CG, PPP5C, PRKCI, PRKCQ, PRKCZ, PRKG1, MAPK3, PSPN, PROC, PROS1, PSG2, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PYY, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTK7, PTPN6, PTPRA, RAB1A, RAB6A, RAB13, RASA2, RFX3, RPGR, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RYK, S100A2, S100A8, S100A9, S100A12, S100P, SAA4, SCN2B, SCN4B, SCNN1B, CCL22, SDC1, SDC2, SELL, SELPLG, SFTPD, ITSN1, SHC1, SIAH1, SIAH2, SIX1, SIX3, SLC9A1, SLC16A1, SLIT1, SLIT3, SNTA1, SOD1, SORD, SOS1, SOS2, SOX1, SOX10, SPG7, SPN, SPTA1, SPTB, SRMS, CDKL5, XCL2, SYK, T, CNTN2, NR2F1, TMF1, TMOD1, TNNC2, TNNI2, TNNI3, TNNT1, TNP2, TNR, TNS1, TPM2, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TYK2, TYRO3, TYROBP, UBB, CLRN1, VAV1, EZR, VIM, DNALI1, LRP8, SCG2, FZD3, ARHGEF5, CUL5, FGF23, SLC7A5, USP9X, USP9Y, EPX, UXT, CUL3, FOXN1, SORBS2, CDC42BPA, OFD1, CNTNAP1, AP3B1, TNFSF11, KLF7, DNAH17, SSNA1, DCHS1, DYNLL1, PEA15, TNFSF12, CD84, AKAP4, VNN2, VNN1, SGPL1, PHOX2B, WASF1, CDK5R2, AP3D1, RPS6KA4, KALRN, DOK2, PSTPIP2, PSTPIP1, DCLK1, RPS6KA5, TAOK2, CER1, NRXN3, KIF3B, NRXN1, HAND2, PSMF1, CDC42BPB, NUP155, FEZ2, SDC3, IFT140, DLGAP5, ZEB2, ELMO1, GAB2, FARP2, KIAA0319, PSMD6, RBX1, KCNE2, ABI1, RANBP9, GPC6, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN1, ARPC2, KIF20A, AKAP9, ABI2, RASA4, WASF2, CHST4, TNK2, PSME3, AP3S2, APC2, KATNB1, SPON2, VAV3, CAP2, CAP1, PROCR, ARPC1A, DPYSL4, SIX2, CHL1, GIPC1, FRS3, AP3M2, IFT27, VAX1, KIF3A, KPTN, SLC7A9, BVES |
1622 | GO:0046822 | 0.00 | 2.49 | 48.41 | 74 | 116 | regulation of nucleocytoplasmic transport | AGTR2, ANGPT1, BARD1, BCL3, BMP4, BMP6, BMPR1A, BRCA1, CAMK4, CD36, CDH1, CDK5, CDKN1A, CDKN2A, CYLD, DAB2, ECT2, EDA, EMD, FLNA, GAS6, GNAQ, SFN, HCLS1, HSP90AB1, IGF1, IL1B, IL10, IL18, JUP, KPNA1, IPO5, SMAD3, PPP1R12A, TONSL, OGG1, PPM1A, PPM1B, PPP3R1, PRKCQ, PTPN14, RBM4, SFRP5, SHH, SLC9A1, SNAI2, SOX4, SP100, TRIP6, ZIC1, AAAS, AKAP1, FZD7, DYRK2, CAMK1, TNFSF14, IL18R1, INPP4B, HDAC3, SLC9A3R1, AKAP6, CABP1, LITAF, TRIM28, NUTF2, APC2, RAPGEF3, TACC3, CREB3, CHERP, RBCK1, KHDRBS1, EDAR, RBPMS |
1623 | GO:0009994 | 0.02 | 2.49 | 10.43 | 16 | 25 | oocyte differentiation | ANG, ATM, BCL2, BRCA2, CCNB1, EREG, GDF9, IGF1, INSL3, PDE3A, PPP2R1A, RPS6KA2, AURKA, ZP3, PDE5A, KIAA0196 |
1624 | GO:0048854 | 0.02 | 2.49 | 10.43 | 16 | 25 | brain morphogenesis | BBS2, BBS4, CTNNA2, EMX1, FGF8, HHEX, OTX1, OTX2, PAX2, SLC6A4, SLIT1, SOX2, FZD3, IFT88, FZD6, HESX1 |
1625 | GO:0001816 | 0.01 | 2.49 | 12.32 | 19 | 30 | cytokine production | AVPR2, CLC, CD55, DBH, DLG1, S1PR3, ELF1, KIT, LIPA, PER1, PIK3CG, ZFP36, EOMES, IQGAP1, ADAMTS3, LITAF, TRIL, TRIM38, BATF |
1626 | GO:0045446 | 0.01 | 2.49 | 15.00 | 23 | 36 | endothelial cell differentiation | ACVR1, S1PR1, S1PR3, F2RL1, GPX1, RAPGEF1, NRG1, ICAM1, RBPJ, IL1B, KDR, LAMA5, PDE4D, PTN, RAP1A, RDX, STC1, TNFRSF1A, EZR, VEZF1, EDF1, RAPGEF2, RAPGEF3 |
1627 | GO:0012501 | 0.00 | 2.48 | 428.33 | 632 | 1027 | programmed cell death | AARS, ABL2, ACTN4, ACTN1, ACVR1, ACVR1B, ADA, ADAR, ADD1, ADORA1, ADORA2A, ADRB2, AES, AGTR2, AHR, AKT2, ALB, ALDH1A3, ALK, ALOX12, ALOX15B, ALX3, BIN1, ANGPT1, SLC25A4, ANXA1, ANXA4, ANXA5, ANXA6, APBB1, APC, BIRC3, XIAP, BIRC5, APLP1, APOH, AQP1, ARF4, ARF6, ARHGAP4, ASNS, ATF3, ATF4, ATM, ATOH1, ATP2A1, AVP, AXL, BAD, BAG1, BARD1, BAX, BCL2, BCL2A1, BCL2L1, BCL3, BDKRB2, BID, BIK, BLK, BMP1, BMP4, BMP6, BMP8B, BMPR2, BMX, BNIP2, BNIP3L, BOK, BRCA1, BRCA2, BTG1, BTK, BUB1, BUB1B, TSPO, C1QBP, CACNA1A, CAMK2A, CASP4, CASP5, CASP6, CASP8, CASP9, CASP10, CAT, CBL, CCK, KRIT1, CD2, CD3G, CD5, CD5L, CD14, CD28, TNFRSF8, TNFSF8, CD38, CD40, CD44, CD59, CD70, CD74, CDC42, CDH1, CDK4, CDK5, CDKN1A, CDKN2A, CHI3L1, CLC, CLU, CNR1, CNTF, COL2A1, COL4A3, COMP, CLDN7, ATF2, CRYAB, CRYBA1, CSF2, CSNK2A1, CSNK2A2, CTGF, CTH, CTLA4, CTNNA1, CX3CR1, CYLD, DAB2, DAD1, DBH, DCC, DDB1, GADD45A, DDX3X, DDX5, DFFA, DFFB, DFNA5, DHCR24, DHODH, DNASE1L3, DNASE2, DNM2, DNMT3A, DPEP1, ATN1, TSC22D3, DSP, DUSP1, E2F2, ECT2, LPAR1, EDNRA, EDNRB, EEF1A2, EGR3, EIF2S1, EPHA2, EIF5A, CTTN, EP300, EPHA7, ERCC3, ERCC5, ERCC6, ERN1, ESR1, ETS1, EYA1, EYA2, F2R, F3, FAP, FCER1G, FGA, FGD1, FGF8, FGFR3, FGG, FLNA, FLT3, FLT4, FNTA, FYN, IFI6, GABRB2, GAPDH, GAS1, GAS2, GAS6, GATA3, GATA6, GCG, GDF9, GDNF, B4GALT1, GNB1, GNGT1, SFN, GPLD1, GPX1, GRID2, GRIN2A, GRINA, GZMH, HCK, HCLS1, HGF, NRG1, HIC1, HIF1A, HIP1, UBE2K, HK2, HMGCR, HPN, HRG, PRMT2, HSPA9, HSPB1, HSP90AB1, IAPP, ICAM1, IFI16, IFIT3, IFNA2, IFNG, IGF1, IGF1R, IGF2R, IGFBP3, IHH, IL1A, IL1B, IL2RA, IL2RB, IL10, IL13, TNFRSF9, ILK, IDO1, ING2, INHA, INS, INSL3, IRAK1, ITGA6, IRF1, IRF5, ISL1, ITGA1, ITGA5, ITGAV, ITGB1, ITPKB, ITPR1, JUN, KDR, KIT, KNG1, KPNA1, KPNB1, KRAS, KRT18, LDHA, LTF, EPCAM, MAD2L1, SMAD3, SMAD6, MAL, MAP3K5, KITLG, MGMT, MAP3K11, CITED1, SLC11A2, YBX1, NTF3, NTF4, NTRK1, NTRK2, NTRK3, NTSR1, OGG1, OPA1, TNFRSF11B, P2RX4, P2RX7, PA2G4, PAEP, PAFAH2, SERPINE1, PARK2, PAWR, PAX2, PCP4, PDE3A, PDE1B, PDK4, PDPK1, PEG3, PF4, PHB, SERPINB9, SERPINB13, PIM1, PIK3CG, PPID, PPP1CA, PPP2CB, PPP2R1A, PPP2R1B, PPP3R1, PPT1, SRGN, PRKAA1, PRKCA, PRKCB, PRKCE, PRKCG, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK3, MAPK8, EIF2AK2, DNAJC3, PROC, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTGIS, PTN, PTPN1, PTPN6, PTPRH, PYGL, RAC1, RAF1, RAG1, RARA, RARB, RB1, DPF2, REST, RPS3, RPS3A, RPS6, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RXRA, RYR2, SORT1, S100A8, S100A9, S100B, SATB1, CCL21, CX3CL1, SET, SFPQ, SFRP4, SFRP5, SGK1, ITSN1, SHB, SHH, SIAH1, SIAH2, ST6GAL1, STIL, SIX1, SIX3, SKP2, SLC9A1, SLIT3, SNAI2, SMPD1, SMPD2, SIGLEC1, SNAI1, SNCB, SNCA, SOD1, SOD2, SON, SOS1, SOS2, SOX2, SOX4, SOX9, SOX10, SP100, SPN, SRPK2, SSTR3, STAR, STAT3, STAT5B, AURKA, STK10, STK11, STXBP1, SUPV3L1, PRDX2, NR2E1, TMF1, TNFAIP3, TNFRSF1A, TNFRSF1B, TOP1, TOP2A, TP73, TPD52L1, TPT1, TRAF1, TRAF2, TRIO, TRPS1, TWIST1, TNFRSF4, TYRO3, UBB, UCN, UNG, VAV1, VDAC2, VDR, VEGFA, VEGFB, VIL1, VIM, VIP, TRPV1, WFS1, WNT11, WRN, XPA, XRCC2, YWHAG, YWHAH, YWHAZ, ZNF16, PAX8, FZD5, SCG2, AIMP2, FZD3, FOSL1, CUL5, DPF1, SRPX, NSMAF, DYRK2, CUL4A, CUL3, CUL2, CUL1, KLF11, OGT, IKBKG, CBX4, API5, MADD, PRKRA, TP63, UNC5C, AKR1C3, DYNLL1, BECN1, PEA15, TRADD, URI1, RIPK1, CRADD, HRK, TNFSF14, TNFSF12, TNFSF10, TNFSF9, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, TRIM24, CFLAR, HDAC3, TSC22D1, ALDH1A2, ARHGEF7, VNN1, SGPL1, TAX1BP1, BCL10, TNFSF18, KALRN, SOCS3, RGN, LATS1, AIFM1, RABEP1, ARHGEF2, BMP15, AURKB, CRLF1, STK17B, STK17A, BCL7C, BCL7B, KLF4, TAOK2, SLIT2, SLC9A3R1, EIF2AK3, ARHGEF6, HAND2, ATG5, PSMF1, LITAF, GDF15, BAG5, BAG4, BAG3, EI24, BCAR1, BRE, TRAF4, AATK, RAPGEF2, SLK, HDAC4, RASSF2, BCLAF1, KIAA0141, RB1CC1, ARHGEF17, ELMO1, PSMD6, AREL1, OXSR1, TNFSF15, NR1H4, CASP8AP2, SRA1, HDAC6, PDCD6IP, PDCD6, BCL2L10, BCL2L11, PARP2, SGK2, FEM1B, TRAP1, RNF41, PSME3, DHRS2, ZNF443, RAMP2, SIGMAR1, SAP18, SMNDC1, TRAIP, CITED2, SEMA3A, RAPGEF3, ACAA2, VAV3, CREB3, STK25, UNC13B, ATG7, ARL6IP5, SIVA1, ERN2, RBCK1, STAMBP, IVNS1ABP, TXNIP, RRAGA, CHL1, TRAF3IP2, ZMYND11, GJB6, PROKR1, MALT1, JTB, EDAR, RNPS1, PRDX3, SERINC3, ERP29, IL24, PIM2, CAPN10, CORO1A, MAP4K5, CHEK2, AKAP13, PHB2, GABARAP |
1628 | GO:0010595 | 0.01 | 2.48 | 15.02 | 23 | 36 | positive regulation of endothelial cell migration | AAMP, ALOX12, ANGPT1, ANXA3, BMP4, BMPR2, SCARB1, ETS1, FLT4, GATA3, GPLD1, HSPB1, KDR, PRKCA, PRKD1, PROX1, SPARC, VEGFA, VEGFC, NRP2, ITGB1BP1, BCAR1, PDCD6 |
1629 | GO:0032663 | 0.01 | 2.48 | 15.02 | 23 | 36 | regulation of interleukin-2 production | ABL2, ANXA1, CD4, CD28, CD80, CD86, GATA3, IL1A, IL1B, PDE4B, PDE4D, PRKCQ, XCL1, SFTPD, STAT5B, TNFAIP3, TRAF2, TNFSF4, EZR, RIPK2, MALT1, GLMN, VSIG4 |
1630 | GO:0043170 | 0.03 | 2.48 | 8.13 | 13 | 22 | macromolecule metabolic process | CALCR, CAMLG, CD9, DNM1, FCER1G, GLE1, AGFG1, SLC2A4, RAB11B, CALCRL, NXF1, ARFGEF2, RAB31 |
1631 | GO:0051050 | 0.00 | 2.48 | 44.82 | 69 | 110 | positive regulation of transport | ABCA1, ADRB2, AHSG, ANGPT1, ATP2B2, AXL, BICD1, TSPO, C3, CA2, CAMK2A, CAV3, CBL, CD36, CD63, CDH3, CCR1, CREBL2, DLG1, DPP6, GPC3, FFAR3, HIP1, ITGA2, ITGAV, ITGB1, KCNE1, KCNJ2, KCNQ1, MFGE8, NTF3, SERPINE1, PARK2, PPT1, PRKCI, PROS1, PRSS8, PTCH1, RAB3B, RAP1A, RAP1GAP, SCN4B, SCN5A, CCL21, SELE, SFRP4, SFTPD, SLC11A1, SLC34A1, STC1, ABCC8, TULP1, VEGFA, VTN, WFS1, CLTCL1, PIK3R3, LIPG, PICK1, ABCG1, TSPAN1, ABCA7, ATP8A1, CREB3, SORBS1, CLDN16, AHCYL1, ARPP19, SLC38A3 |
1632 | GO:0006414 | 0.00 | 2.48 | 37.98 | 58 | 91 | translational elongation | AARS, DIO2, EEF1A2, EEF1B2, EEF2, EIF5A, FAU, RPL10A, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, SRP9, TUFM, RPL14, RPL23, GTPBP1, TSFM, USP16, RPL35 |
1633 | GO:2001233 | 0.00 | 2.48 | 43.15 | 66 | 104 | regulation of apoptotic signaling pathway | ACVR1, AVP, BDKRB2, BRCA1, CD44, CD74, CDKN2D, COL2A1, CSF2, CTH, CX3CR1, DBH, DDX3X, CTTN, EYA1, FGA, FGG, FYN, IFI6, GCG, GDNF, GPX1, GRINA, HGF, NRG1, HIF1A, HSPB1, ICAM1, IGF1, IL1A, IL1B, ING2, INS, ITGA6, ITGAV, OPA1, SERPINE1, PF4, PTPN1, RAF1, CX3CL1, SIAH2, SNAI2, SNAI1, SOD2, SP100, TNFAIP3, TPT1, TRAF1, VDAC2, WFS1, SCG2, MADD, URI1, VNN1, ARHGEF2, BAG5, RB1CC1, BCL2L10, FEM1B, TRAP1, PSME3, CREB3, IVNS1ABP, ZMYND11, ERP29 |
1634 | GO:0015718 | 0.00 | 2.47 | 22.87 | 35 | 55 | monocarboxylic acid transport | AGTR2, AKT2, ABCD1, ANXA1, BDKRB2, SLC25A20, CD36, CPT1B, CPT2, ACE, ACSL1, ACSL3, ACSL4, GOT2, IL1B, OXT, P2RX4, P2RY2, PRKAB2, ABCD3, SLC16A1, SLC22A5, SYK, CYP4F2, TNFSF11, SLC5A6, SLC16A6, SLC16A5, SLC16A4, SLC16A7, SLC22A13, ABCC4, SLC25A17, SLC27A4, SLC27A2 |
1635 | GO:0071375 | 0.02 | 2.47 | 11.04 | 17 | 27 | cellular response to peptide hormone stimulus | ANXA5, CDC5L, CDC6, CSH1, CYP11B1, FBN1, GH2, GNRHR, NR4A1, MEN1, PTPN6, SSTR2, SSTR3, STAT3, STAT5B, WNT1, AKAP1 |
1636 | GO:0002683 | 0.00 | 2.46 | 24.81 | 38 | 60 | negative regulation of immune system process | ADA, ADORA1, ATM, AXL, PRDM1, BPI, C5, CBLB, CD86, CD37, CNR1, CNR2, DLG1, TSC22D3, ELF1, F2RL1, FCER1G, IDO1, KITLG, PAWR, PDPK1, PRKAR1A, PTGER4, PTPRJ, CCL21, CCL25, SFTPD, SOX9, SOX11, SCGB1A1, EZR, PDE5A, BCL10, SOCS6, SLIT2, NR1D1, GLMN, VSIG4 |
1637 | GO:0008544 | 0.00 | 2.46 | 55.81 | 85 | 134 | epidermis development | AARS, ACVR1B, ALDH3A2, ANXA1, APC, STS, ATP2B2, BCL2, CDC42, COL17A1, CST6, CTGF, CTSV, CUX1, DBI, DNASE1L2, DSP, EDA, EPHA2, ELF3, EMP1, EREG, ERCC3, FGF7, FLG, FLOT2, GFI1, GJB5, GNAS, IGF1R, IGFBP5, RBPJ, IVL, KRTAP5-9, KRT2, KRT5, KRT14, KRT15, KRT16, KRT31, KRT32, KRT34, KRT83, LAMA3, LAMA5, NTF3, NTF4, OVOL1, PPL, KLK7, PTHLH, RAC1, RBP2, SATB1, SHH, SNAI1, SOD1, SOX9, SPRR1B, SPRR2A, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3, ST14, TSG101, USH2A, CLRN1, FZD3, IFT88, MADCAM1, FZD6, AKR1C3, ADAM9, SCEL, LATS1, KLF4, SLC9A3R1, SEC24B, AGPAT2, TXNIP, EDAR, SPINK5, SOX21 |
1638 | GO:0010565 | 0.00 | 2.46 | 21.59 | 33 | 52 | regulation of cellular ketone metabolic process | ACADL, ACADVL, AKT2, ANXA1, APOA1, APOA4, APOC2, AVP, BMP6, BRCA1, CNR1, DLD, GCG, KAT2A, GHSR, GK, INSIG1, PDK4, PRKAB2, PRKCE, REST, SNCA, SREBF1, STK11, TWIST1, NR1H2, PDHX, AKR1C3, KAT2B, RGN, EIF2AK3, ERLIN1, ERLIN2 |
1639 | GO:0034605 | 0.03 | 2.46 | 9.16 | 14 | 22 | cellular response to heat | CDKN1A, CETN1, DHX9, EIF2S1, FGF1, HSPA6, IL1A, IRAK1, ATXN3, MKI67, STAC, HDAC6, PDCD6, ARPP21 |
1640 | GO:0042308 | 0.01 | 2.45 | 13.77 | 21 | 33 | negative regulation of protein import into nucleus | ANGPT1, CD36, CYLD, EMD, GAS6, IL10, TONSL, PPM1A, PPM1B, SFRP5, SNAI2, TRIP6, AKAP1, DYRK2, TNFSF14, SLC9A3R1, CABP1, LITAF, APC2, TACC3, CREB3 |
1641 | GO:0043620 | 0.01 | 2.45 | 13.77 | 21 | 33 | regulation of DNA-templated transcription in response to stress | ARNT, ATF3, ATF4, BACH1, EP300, HIF1A, RBPJ, JUN, RPS6KA1, RPS6KA3, RPS27A, UBB, UBE2D1, UBE2D2, VEGFA, CUL2, BCLAF1, RBX1, KLF2, CITED2, RGS14 |
1642 | GO:0000272 | 0.03 | 2.45 | 9.18 | 14 | 22 | polysaccharide catabolic process | ADRA1B, CALM3, CPS1, G6PC, GAA, INS, PGM1, PHKA2, PHKG1, PPP1CA, PYGL, PYGM, MGAM, STBD1 |
1643 | GO:0009394 | 0.03 | 2.45 | 9.18 | 14 | 22 | 2'-deoxyribonucleotide metabolic process | ADA, ADK, AK2, DTYMK, DUT, GUK1, NUDT1, NTHL1, OGG1, SHMT1, TYMS, UNG, MBD4, TBPL1 |
1644 | GO:0035315 | 0.03 | 2.45 | 9.18 | 14 | 22 | hair cell differentiation | ATOH1, ATP2B2, CUX1, ERCC3, GFI1, HES1, RBPJ, RAC1, SOD1, USH2A, CLRN1, SLC9A3R1, SEC24B, SPINK5 |
1645 | GO:0046326 | 0.03 | 2.45 | 9.18 | 14 | 22 | positive regulation of glucose import | AKT2, CREBL2, GPC3, FFAR3, IGF1, INS, PRKCI, PRKCZ, RAP1A, CLTCL1, PIK3R3, SORBS1, ARPP19, CAPN10 |
1646 | GO:0046627 | 0.03 | 2.45 | 9.18 | 14 | 22 | negative regulation of insulin receptor signaling pathway | AHSG, CISH, IL1B, YBX1, ENPP1, PRKCA, PRKCB, PRKCQ, PRKCZ, PTPN1, PTPRE, TSC1, TSC2, SOCS3 |
1647 | GO:0048512 | 0.03 | 2.45 | 9.18 | 14 | 22 | circadian behavior | ADA, ADORA1, ALB, CHRNB2, GHRH, GHRHR, KCNA2, KCND2, PTGER4, SIX3, SRD5A1, STAR, PER3, USP2 |
1648 | GO:0043549 | 0.00 | 2.45 | 200.04 | 300 | 480 | regulation of kinase activity | ACVR2B, ADAR, ADARB1, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADORA1, ADRA2C, ADRB2, ALK, ANG, ANGPT1, APC, APLP2, BAD, BAX, CCND1, BMP4, C5, CALM3, CAMK2A, CAMK2G, CAV3, CCNC, CCND3, CCNE1, CCNH, CCNT1, CCNT2, CD4, CD40, CD74, CDC6, CDC25C, CDK4, CDK5, CDKN1A, CDKN2A, CDKN2C, CDKN2D, CENPE, CHAD, CHI3L1, CISH, CKS1B, CLU, CSF2, CSF2RB, CSPG4, DCN, ACE, GADD45A, DLG1, HBEGF, DUSP1, DUSP4, DUSP5, DUSP7, DUSP9, ECT2, LPAR1, EDN3, EFNA1, EFNA5, EMP2, EPHA1, EPHA4, ERBB2, EREG, ERCC6, ERN1, F2R, ACSL1, FCER1A, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR4, FPR1, FYN, GAS6, GCG, GNAQ, SFN, GP1BA, GPS2, GRB2, RAPGEF1, GRIN2A, GRM1, HGF, NRG1, HHEX, HMGCR, FOXA2, HSPB1, HSP90AB1, IGF1R, IGF2, IL1B, IL2RA, IL2RB, IL2RG, ILK, INS, IRAK1, IRAK2, ITGA1, KRAS, LTF, MARK3, MAP3K5, MEN1, KITLG, MAP3K11, NRAS, NTF3, NTRK1, NTRK3, DDR2, P2RX7, PEBP1, PARK2, PCP4, PDE6G, PDE6H, PDPK1, PFKFB2, PIK3CB, PIM1, PIK3CG, PPP1R1A, PPP2R1A, PPP5C, PRKAA1, PRKAB2, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCZ, MAPK3, EIF2AK2, DNAJC3, PROX1, PRPSAP1, RELN, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN1, PTPN6, PTPRA, PTPRJ, RAC2, RAF1, RANBP2, RAP1A, RAP2B, RASA2, RGS2, RPS3, RPS27A, S100A12, SERPINB3, SDC4, SHC1, STIL, SLC11A1, SMPD1, SNCA, SOD1, SORL1, SOS1, SPTA1, SPTB, STK10, STK11, SYK, TAF7, TARBP2, NR2F2, TNFAIP3, TP73, TPD52L1, TRAF2, TSC1, TSC2, TSG101, TNFRSF4, UBB, UCN, UVRAG, VEGFA, WNT11, YWHAG, ZNF16, ZP3, LRP8, FZD5, ARHGEF5, FGF23, FZD4, FZD8, CUL3, IKBKG, IKBKAP, CAMK1, MAPKAPK5, MADD, TNFSF11, PDE5A, PEA15, RIPK1, ADAM9, RIPK2, TNFRSF10B, TNFRSF10A, IQGAP1, KAT2B, CDK5R2, SOCS3, DIRAS3, RGN, LATS1, CCNE2, VAPB, ITGB1BP1, S1PR2, SOCS6, TAOK2, SLC9A3R1, PSMF1, GMFG, CARTPT, TRAF4, RAPGEF2, SLK, RASSF2, ZEB2, PSMD6, OXSR1, TNFSF15, RBX1, ABI1, TOM1L1, RAD50, AKAP9, RASA4, PSME3, TRIB1, STK25, HEXIM1, RGS14, NRG3, FRS3, MALT1, JTB, COPS8, PRDX3, ERP29, UBE2C, CDC37, MAP4K5, FZD10, AKAP13, DUSP12, STK38 |
1649 | GO:0006805 | 0.00 | 2.44 | 34.20 | 52 | 82 | xenobiotic metabolic process | ACY1, ADH1B, ADH5, AHR, ALDH1A1, ALDH2, ALDH3A1, ALDH1B1, AOC2, COMT, CYP1A2, CYP2A6, CYP2A13, CYP2F1, CYP3A4, CYP3A5, CYP8B1, CYP11B1, CYP24A1, CYP27B1, CYP51A1, DPEP1, ESD, FDXR, FMO3, GSS, GSTZ1, MGST2, PTGIS, PTGS1, S100A12, STAR, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, SULT2A1, TPMT, UGDH, UGP2, UGT2B4, CYP4F2, AOC3, CES2, NR1I2, AIP, PAPSS2, PAPSS1, GLYAT, AKR1A1, SLC26A1 |
1650 | GO:0045926 | 0.01 | 2.44 | 12.46 | 19 | 30 | negative regulation of growth | ADRB2, ALOX15B, BBS2, BMP4, CD36, CTSG, CXADR, FGFR3, GPC3, GNAS, HIF1A, IFNG, IGFBP5, IL10, KCNK2, PTCH1, SLC6A4, TP73, RAI1 |
1651 | GO:0009161 | 0.00 | 2.44 | 32.88 | 50 | 79 | ribonucleoside monophosphate metabolic process | ALDOB, ALDOC, ARNT, ATP1A2, ATP6V1A, ATP6V1B1, ATP6V1B2, BAD, BPGM, TSPO, COX4I1, COX8A, COX15, CTNS, DLD, DLG1, DLG2, DLG3, ENO2, GAPDH, GPD1, GUK1, HIF1A, HK2, HSPA8, IGF1, INS, LDHA, OGDH, P2RX7, PFKFB2, PFKFB4, PGAM2, PGK1, PGK2, PGM1, PPP2R5D, PRKAA1, SDHC, SNCA, TAZ, UQCRB, UQCRC1, UQCRC2, UQCRH, OGT, COX5A, HDAC4, COQ7, ECD |
1652 | GO:0030307 | 0.00 | 2.43 | 25.01 | 38 | 60 | positive regulation of cell growth | ADAM10, ALOX12, AVP, BCL2, CD38, CDC42, CSNK2A1, CYBA, DDX3X, HBEGF, EFNA5, ERBB2, EXTL3, ACSL4, SFN, HIST1H1B, H3F3B, HPN, IGF1, INS, PARK2, EXOSC9, RPS6KA1, RPS6KA3, S100A8, S100A9, SDCBP, SGK1, SLC9A1, SUPV3L1, SYT1, SYT4, UCN, RND2, CPNE6, AKAP6, RIMS2, IST1 |
1653 | GO:0022603 | 0.00 | 2.43 | 54.43 | 83 | 133 | regulation of anatomical structure morphogenesis | ACVRL1, ADA, ADRB2, ALOX12, ANGPT2, ANXA3, APOH, KLK3, AQP1, ADGRB2, BNIP3, BRCA1, BTG1, C3, C5, KRIT1, CD36, CD53, CDX1, CDX2, CHI3L1, CCR3, COL4A3, CX3CR1, DCN, DHODH, ECM1, EPHA2, EMP2, EPHA1, ERBB2, ERG, ETS1, F3, FLT1, FLT3LG, FLT4, GATA4, GATA6, GTF2I, HHEX, HIF1A, HRG, HSPB1, IL1A, ITGA5, KRT1, FOXO4, NTRK1, OPA1, SERPINE1, PDE3B, SERPINF1, PF4, PRKCA, PRKCB, PRKD1, PROX1, PTGER4, PTGIS, PTPRM, RAP1A, RRAS, CX3CL1, SFRP5, SP100, VEGFB, VEGFC, CAMK1, TNFSF14, TNFSF13, TNFSF12, ADAM9, CFLAR, GDF15, PDCD6, RAMP2, RAPGEF3, CXCL13, DMRT2, TNFSF13B, EHD1, SPINK5 |
1654 | GO:0048872 | 0.01 | 2.43 | 15.76 | 24 | 38 | homeostasis of number of cells | ADA, TNFRSF17, CACNA1F, CD74, TSC22D3, EMX1, IL2RA, LMO1, RAG1, SLC22A5, SOS1, SOS2, SPTA1, TNFAIP3, IFT88, FOXN1, IKBKG, TNFSF14, BCL10, CCNB2, CHST3, RASSF2, SIVA1, TNFSF13B |
1655 | GO:0010810 | 0.05 | 2.43 | 7.87 | 12 | 19 | regulation of cell-substrate adhesion | BCL2, EFNA5, EPHA3, GPM6B, ONECUT1, ATXN3, PIK3CB, RAC2, ST6GAL1, SLC9A1, ONECUT2, SLK |
1656 | GO:0071822 | 0.00 | 2.42 | 51.56 | 79 | 128 | protein complex subunit organization | BNIP3, CHD3, DYNC1H1, DSP, EIF5A, EML1, FAU, AGFG1, KRT14, RPL10A, PCM1, PPP1CA, RAN, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, SHH, STIL, SLN, VIM, IFT88, SMC1A, RPL14, PRC1, SMC3, RPL23, CRIPT, SLK, CKAP5, IST1, DNAJC6, PARP3, SMC4, APC2, KATNB1, TRDN, TACC3, TACC2, GAS2L1, RGS14, DCTN6, RPL35 |
1657 | GO:1901361 | 0.01 | 2.42 | 14.42 | 22 | 35 | organic cyclic compound catabolic process | AMBP, AOX1, BLVRA, BLVRB, CCBL1, COMT, CYP2A6, DAO, DBH, DIO3, GOT2, GSTZ1, HAL, HPD, IDO1, ALDH6A1, PAH, QDPR, TAT, ALDH4A1, KYNU, ALDH1L1 |
1658 | GO:0009966 | 0.00 | 2.42 | 29.05 | 45 | 74 | regulation of signal transduction | ANXA2, BIRC5, CACNA1F, CNGA1, CD55, DTX1, STOM, FNTA, GAS1, GNAT1, GNB1, GNGT1, GUCA1A, GUCA1B, GUCY2F, GUCY2D, HSP90AB1, IFNGR1, IRF1, LLGL2, OTX2, PDCL, PPP1R2, PRCP, RCVRN, RS1, SAG, STAT2, SYP, DYNLT1, TYK2, SUMO1, ZIC1, TAX1BP1, BAZ1B, GUCA1C, IFT140, KCNE2, SRA1, RAMP2, RAMP3, CACNG2, SLC9A6, CDC37, USP18 |
1659 | GO:0048584 | 0.01 | 2.42 | 14.77 | 23 | 38 | positive regulation of response to stimulus | APBB1, BRCA1, CEBPG, EYA3, HMGA1, INSL3, KCNK2, MGMT, ATXN3, REG3A, PRKCG, RREB1, SETMAR, SGTA, SNCA, TRPC3, TRPM2, PIK3R3, USP13, RNF8, RGN, BRE, TRIM28 |
1660 | GO:0031401 | 0.00 | 2.42 | 277.08 | 411 | 665 | positive regulation of protein modification process | ABL2, ACVR1, ACVR1B, ACVR2A, ACVR2B, ACVRL1, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADORA1, ADRA1B, ADRA2C, ADRB2, AGTR2, AKT2, ALK, ANG, ANGPT1, ANXA2, BIRC3, XIAP, ARNT, ATM, ATP6AP1, AVP, AVPR2, BAX, CCND1, BCL2, BMI1, BMP1, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, C3, C5, CALM3, CAMK2A, CAMK2G, CAV2, CAV3, CCK, CCNB1, CCNC, CCND3, CCNH, CCNT1, CCNT2, CD4, CD80, CD36, CD40, CD44, CD74, CDC6, CDC20, CDC27, CDC42, CDK5, CDK9, CDKN1A, CDKN2A, CENPE, CHI3L1, CLU, CCR1, CNTF, CREBL2, CSF2, CSF2RB, CSNK1D, CSPG4, CTF1, CTGF, DAB2, ACE, GADD45A, DLG1, DNMT1, DNMT3B, HBEGF, DUSP5, DUSP7, DUSP9, DYRK1A, GPR183, ECT2, LPAR1, EDN3, EDNRA, EDNRB, EFNA1, EFNA5, EMP2, EPHA4, EPHA7, EPHA8, ERBB2, EREG, ERCC6, ERN1, ESR1, F2R, F2RL1, ACSL1, FCER1A, FGA, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FGG, FLT1, FLT3, FLT3LG, FLT4, FNTA, FPR1, FSHR, FYN, GAS6, GCG, GDF9, GOLGA2, GPLD1, GRB2, RAPGEF1, GRIN2A, GRM1, HIST1H1B, HCLS1, HGF, NRG1, UBE2K, HMGCR, HPX, PRMT1, HES1, DNAJB2, HSP90AB1, HTR2C, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF1R, IGF2, IGFBP3, IL1A, IL2RA, IL2RB, IL2RG, IL13, IL18, ILK, INHA, INS, IRAK1, IRAK2, ITGA1, ITGA2, ITGA5, ITGB1, JARID2, JUN, KDR, KISS1, KIT, KRAS, LTF, SMAD3, SMAD7, MARK3, MAP3K5, KITLG, MAP3K11, PPP1R12A, NRAS, NTF3, NTRK1, NTRK2, NTRK3, DDR2, TNFRSF11B, P2RX7, P2RY1, PEBP1, PARK2, PAWR, PDE6G, PDE6H, ENPP2, PDPK1, PFN2, PHB, PIK3CB, PIM1, PIK3CG, PPP1R7, PPP5C, PRKAA1, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCE, PRKD1, PRKCZ, EIF2AK2, PROX1, RELN, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTGER4, PTPN1, PTPRA, PTPRZ1, RAC1, RAF1, RAP1A, RAP2A, RAP2B, RASA2, RPS3, RPS27A, RYK, S100A12, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SDCBP, SHC1, STIL, SKP1, SKP2, SLAMF1, SLC11A1, SMPD1, SUMO3, SNCA, SOD1, SOS1, SOX2, SOX9, SPN, SPTA1, SPTB, SREBF1, STK10, STK11, XCL2, SYK, TNFRSF1A, TNFRSF1B, TP73, TPD52L1, TRAF2, TNFRSF4, UBB, UBE2D1, UBE2L3, UBE3A, UCN, VEGFA, VEGFB, VEGFC, VTN, WFS1, WNT1, WNT11, ZP3, LRP8, FZD5, AIMP2, ARHGEF5, FGF23, CDK2AP1, SYMPK, FZD4, FZD7, FZD8, BCAR3, CUL3, CUL1, OGT, SEMA7A, IKBKG, MAPKAPK5, CDC14B, MADD, TNFSF11, PDE5A, PEA15, CDC23, EED, RIPK1, ADAM9, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10B, TNFRSF10A, IQGAP1, HDAC3, CDC16, BCL10, CDK5R2, TNFSF18, RGN, LATS1, ARHGEF2, BMP15, VAPB, CRLF1, ITGB1BP1, GPR55, S1PR2, TAOK2, AKAP6, PSMF1, GDF15, BAG4, CARTPT, TRAF4, RAPGEF2, SLK, HDAC4, RASSF2, RNF40, RB1CC1, ZEB2, PSMD6, OXSR1, TNFSF15, RBX1, ABI1, TOM1L1, RAD50, AKAP9, RASA4, SORBS3, TNK2, PSME3, ABCA7, ANAPC10, PIAS3, MAD2L2, STK25, ATG7, ARL6IP5, ARFGEF1, NRG3, FRS3, MALT1, JTB, COPS8, ERP29, IL24, RBPMS, UBE2C, MAP4K5, RASSF1, CHEK2, FZD10, PHB2 |
1661 | GO:0044242 | 0.00 | 2.42 | 31.66 | 48 | 76 | cellular lipid catabolic process | ACAA1, ACADL, ACADM, ACADS, ACADSB, ACADVL, ACOX1, ADRB2, AKT2, ABCD1, CNR1, CPT1B, CPT2, DECR1, ECH1, EHHADH, ETFA, ETFDH, FAAH, GALC, GM2A, HADHA, HEXB, HSD17B4, IDH1, IVD, PCCA, PPT1, ABCD3, SCP2, SMPD1, TWIST1, RAB7A, ACOX2, ACOX3, CYP4F2, AKR1C3, SGPL1, LIPG, PRDX6, ACOT8, ECI2, SLC25A17, SPTLC1, SMPDL3A, SLC27A4, SLC27A2, ACOT7 |
1662 | GO:1902305 | 0.01 | 2.42 | 12.52 | 19 | 30 | regulation of sodium ion transmembrane transport | ACTN4, ARF1, ATP1A2, ATP1B3, FXYD2, CAV3, DLG1, DNM2, STOM, FXYD3, PRKCE, PTPN3, SCN2B, SCN4B, SCN5A, SLC9A1, SNTA1, YWHAH, SLC9A3R1 |
1663 | GO:1903146 | 0.01 | 2.42 | 12.52 | 19 | 30 | regulation of mitophagy | ACTL6A, ADRB2, BNIP3L, TSPO, CSNK2A2, CTSK, CTTN, KAT2A, HIF1A, PARK2, RPL28, SREBF1, U2AF1, ZBTB17, FZD5, BECN1, ATG5, HDAC6, ATG7 |
1664 | GO:0072089 | 0.05 | 2.42 | 7.89 | 12 | 19 | stem cell proliferation | DAGLA, EML1, FGF7, GPC3, KCNA1, ABCB1, SOX5, FZD9, NUMB, NUMBL, HAND2, SIX2 |
1665 | GO:0042692 | 0.02 | 2.42 | 11.17 | 17 | 27 | muscle cell differentiation | BIN1, CDK9, CSRP2, DTYMK, EDNRB, FGF6, FLOT2, HMGCR, ISL1, NTF3, REST, SIX1, SMARCA2, T, ITGA8, QKI, GLMN |
1666 | GO:0033047 | 0.00 | 2.42 | 20.45 | 31 | 49 | regulation of mitotic sister chromatid segregation | APC, ATM, ATRX, BUB1, BUB1B, CCNB1, CDC6, CDC20, CDC27, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, MAD2L1, RB1, UBE2D1, ZNF207, CUL3, TNKS, BECN1, CDC23, CDC16, ZW10, BUB3, DLGAP5, ANAPC10, MAD2L2, PTTG2, UBE2C, CIT |
1667 | GO:0009410 | 0.00 | 2.42 | 39.65 | 60 | 95 | response to xenobiotic stimulus | ACY1, ADH1B, ADH5, AHR, ALDH1A1, ALDH2, ALDH3A1, ALDH1B1, AOC2, COMT, CRYZ, CYP1A2, CYP2A6, CYP2A13, CYP2F1, CYP3A4, CYP3A5, CYP8B1, CYP11B1, CYP24A1, CYP27B1, CYP51A1, DPEP1, ESD, ACSL1, FDXR, FMO3, GPX1, GSS, GSTM1, GSTM2, GSTZ1, MGST2, PTGIS, PTGS1, RB1, S100A12, STAR, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, SULT2A1, TPMT, SCGB1A1, UGDH, UGP2, UGT2B4, CYP4F2, AOC3, CES2, NR1I2, AIP, PAPSS2, PAPSS1, GSTO1, GLYAT, AKR1A1, SLC26A1 |
1668 | GO:0007269 | 0.00 | 2.42 | 23.74 | 36 | 57 | neurotransmitter secretion | ABAT, CACNA1B, CDK5, GAD1, GAD2, GLS, HSPA8, P2RX7, PPT1, PTPRN2, SLC1A6, SLC1A7, SLC6A11, SLC6A12, SLC6A13, SLC22A2, SNAP25, SYT1, SYT4, SYN3, DOC2A, CADPS, STX11, SNAP23, LIN7A, SYNJ1, DGKI, SNAP29, NRXN3, NRXN1, NRXN2, RIMS2, SNPH, CPLX2, CPLX1, HRH3 |
1669 | GO:0030335 | 0.00 | 2.41 | 37.53 | 57 | 91 | positive regulation of cell migration | ACP5, ACTN4, ACVR1, ACVR1B, AKT2, APC, ARHGAP5, CGA, COL1A1, DAB2, DIAPH1, S1PR1, EPHA1, F2R, F10, FBLN1, FGF1, FGR, FLT1, GRB7, HGF, ONECUT1, IGF1R, ILK, INS, ITGA5, ITGAV, ITGB1, KIT, SMAD3, NTF3, NTRK3, RELN, PTPRZ1, RDX, SERPINB3, SDCBP, SEMA3F, SNAI2, SNAI1, TRIP6, WNT11, PTP4A1, SEMA3B, SEMA7A, IKBKAP, NUMB, ONECUT2, RAPGEF2, SEMA3E, SEMA3A, ATP8A1, SEMA6C, SEMA6B, SEMA4F, SEMA4B, CORO1A |
1670 | GO:0021537 | 0.00 | 2.41 | 38.34 | 58 | 92 | telencephalon development | ALDH1A3, ANXA3, AQP1, ATOH1, AVPR2, BAD, BAX, BBS2, BBS4, BMP4, CDK6, COL3A1, DBI, DNAH5, LPAR1, EMX1, EMX2, EPHA5, EPHB2, EPHB3, EXT1, EZH1, FGF8, KAT2A, HIF1A, HPRT1, HES1, KCNA1, NTRK2, PROX1, PTPRZ1, RARA, RARB, RFX4, RYK, SALL1, SCN5A, TRA2B, SHH, SIX3, SLC8A1, SLC8A3, SOX2, SRD5A1, TACC1, NR2F1, TP73, TSC1, IFT88, USP9X, EOMES, SEMA7A, NUMB, NUMBL, ZEB2, TACC3, ATG7, TACC2 |
1671 | GO:0009888 | 0.00 | 2.41 | 57.39 | 88 | 144 | tissue development | ADA, ADRB2, AHSG, AMBN, AMELY, ASCL2, ASGR2, ATF3, BGLAP, CACNA1S, CACNB4, CAV2, CDK5, CENPF, CCR1, COL19A1, CXADR, DCN, DDX5, DHCR24, TSC22D3, ECM1, EEF2, EGR2, EMD, NR5A1, GAA, GAS6, GPC1, GPM6B, HLF, HLX, HMGCR, ITGA6, ITGAM, KCNK2, KRT6B, LTF, NRAS, DDR2, OMD, OGDH, P2RX7, ENPP1, PHEX, PLN, SRGN, PRKAA1, RB1, RYR1, S100B, SGCB, SGCD, SLC9A1, SVIL, TAZ, KLF10, CLEC3B, TP73, TUFT1, COL14A1, XK, ZBTB17, CSRP3, FGF23, SORBS2, SAP30, NRP2, HDAC3, USP2, CTDP1, ITGB1BP1, GTF3C5, AKAP6, ATG5, MINPP1, HDAC4, NR1D2, LRRC17, SPEG, HMG20B, GPNMB, ATG7, PDLIM5, VAMP5, USP19, VAX1, BVES |
1672 | GO:0051341 | 0.05 | 2.41 | 7.91 | 12 | 19 | regulation of oxidoreductase activity | ACVR2A, CAV3, CNR1, CNR2, DNM2, GFI1, HP, HSP90AA1, IL13, OXA1L, PARK2, HDAC6 |
1673 | GO:0008630 | 0.00 | 2.41 | 23.79 | 36 | 57 | intrinsic apoptotic signaling pathway in response to DNA damage | ATM, BAD, BAX, BCL2, BCL2A1, BCL2L1, BCL3, BOK, BRCA1, BRCA2, CASP9, CD44, CD74, CDKN1A, CDKN2D, CLU, EPHA2, EP300, ERCC6, SFN, HIC1, IFI16, ING2, RPS3, SNAI2, SNAI1, TNFRSF1A, TNFRSF1B, TP73, TPT1, XPA, DYRK2, TP63, BCL2L10, BCL2L11, CHEK2 |
1674 | GO:0034111 | 0.00 | 2.41 | 23.79 | 36 | 57 | negative regulation of homotypic cell-cell adhesion | ABAT, ADRB2, ALOX12, ANXA1, BMP4, CBLB, CD74, CDKN2A, CTLA4, CYLD, DLG1, DTX1, ERBB2, HLX, IFNA2, IHH, IL2RA, IL10, IDO1, IRF1, PAWR, PRKAR1A, PRKG1, PTPN6, RDX, XCL1, SFTPD, SHH, SPN, TNFSF4, SCGB1A1, PDE5A, TNFSF18, SOCS6, GLMN, VSIG4 |
1675 | GO:0042752 | 0.01 | 2.41 | 15.84 | 24 | 38 | regulation of circadian rhythm | ADCY1, ARNTL, CHRM1, CRY1, CRY2, CSNK1D, GNAQ, PER1, PPP1CA, PRKAA1, PRKCG, MAPK8, PROX1, RBM4, SFPQ, SUV39H1, KLF10, TOP2A, UBE3A, SOX14, USP2, NR1D1, CLOCK, NR1D2 |
1676 | GO:0002708 | 0.01 | 2.40 | 15.86 | 24 | 38 | positive regulation of lymphocyte mediated immunity | AP1G1, C3, CD28, CD40, FCER1A, FCER1G, FCER2, HPX, IFNG, IL1B, P2RX7, PRKCZ, PVR, XCL1, STAT5B, TRAF2, TNFSF4, UNG, VAV1, WHSC1, ZP3, FZD5, TNFSF13, MALT1 |
1677 | GO:0050871 | 0.05 | 2.40 | 7.92 | 12 | 19 | positive regulation of B cell activation | BAD, PRDM1, BTK, CD28, IFNG, STAT5B, SYK, TNFSF4, UNG, WHSC1, TNFSF13, IKZF1 |
1678 | GO:0086010 | 0.05 | 2.40 | 7.92 | 12 | 19 | membrane depolarization during action potential | CACNA1A, CACNA1B, CACNA1E, CACNA1F, CACNA1S, PTPN3, SCN1A, SCN3A, SCN8A, SCN10A, YWHAH, SCN11A |
1679 | GO:0019369 | 0.05 | 2.40 | 7.92 | 12 | 19 | arachidonic acid metabolic process | ALOX12, ALOX15B, DAGLA, DPEP1, FAAH, GPX1, HPGD, LTA4H, MAPK3, PTGIS, PTGS1, AKR1C3 |
1680 | GO:0002762 | 0.05 | 2.40 | 7.93 | 12 | 19 | negative regulation of myeloid leukocyte differentiation | APCS, C1QC, INHA, LTF, RARA, CUL4A, INPP4B, GPR55, CARTPT, TRIB1, LRRC17, FSTL3 |
1681 | GO:0006929 | 0.05 | 2.40 | 7.93 | 12 | 19 | substrate-dependent cell migration | ABL2, CTTN, EPHA8, FBLN1, ITGA2, OPHN1, SDCBP, SNAI2, VEGFC, ITGB1BP1, SLIT2, SEMA3A |
1682 | GO:0010765 | 0.05 | 2.40 | 7.93 | 12 | 19 | positive regulation of sodium ion transport | ACTN4, ADRB2, ARF1, ATP1B3, DNM2, PRSS8, SCN4B, SCN5A, SGK1, SLC9A1, SGK2, AHCYL1 |
1683 | GO:0030890 | 0.05 | 2.40 | 7.93 | 12 | 19 | positive regulation of B cell proliferation | ADA, BCL2, CD38, CD40, CD74, CDKN1A, CHRNB2, GPR183, IL13, TNFRSF4, VAV3, TNFSF13B |
1684 | GO:0042462 | 0.05 | 2.40 | 7.93 | 12 | 19 | eye photoreceptor cell development | BBS4, PRDM1, GNAT1, GNAT2, GNGT1, NRL, NTRK2, PRKCI, RPGR, TULP1, VEGFA, NR2E3 |
1685 | GO:0045736 | 0.05 | 2.40 | 7.93 | 12 | 19 | negative regulation of cyclin-dependent protein serine/threonine kinase activity | APC, CDKN1A, CDKN2A, HHEX, MEN1, NR2F2, TNFAIP3, CUL3, KAT2B, LATS1, HEXIM1, UBE2C |
1686 | GO:0045773 | 0.05 | 2.40 | 7.93 | 12 | 19 | positive regulation of axon extension | BMPR2, GOLGA4, NRG1, ILK, LIMK1, NTRK3, SRF, CDKL5, VEGFA, SEMA7A, RAB11A, TWF2 |
1687 | GO:0060997 | 0.05 | 2.40 | 7.93 | 12 | 19 | dendritic spine morphogenesis | CDK5, CTNND2, EFNA1, EPHA4, EPHB1, EPHB2, EPHB3, CAPRIN1, RELN, LRP8, BAIAP2, PDLIM5 |
1688 | GO:0061005 | 0.05 | 2.40 | 7.93 | 12 | 19 | cell differentiation involved in kidney development | ACTA2, BMP4, GATA3, HES1, PAX2, PRKX, PTCH1, SHH, PAX8, IQGAP1, PROM1, SIX2 |
1689 | GO:1903900 | 0.00 | 2.39 | 40.48 | 61 | 97 | regulation of viral life cycle | ADAR, ADARB1, APCS, BCL2, BST2, CAV2, CCNH, CCNT1, CD28, CDK9, CHD1, DDB1, DDX3X, DDX5, EP300, STOM, ERCC3, FCN1, GTF2F1, HPN, IFI16, IFIT1, IFNA2, ISG20, JUN, LTF, OAS1, OAS3, PARK2, PPIB, PPID, EIF2AK2, PROX1, REST, SLPI, SMARCA4, SP1, SP100, SRPK2, SSRP1, STAU1, SUPT4H1, TARBP2, TMPRSS2, TOP2A, TSG101, TRIM25, FCN3, OASL, CTDP1, VAPB, VAPA, TRIM28, TNIP1, IFITM3, PPIE, PPIH, TRIM38, IFITM2, SUPT16H, SNF8 |
1690 | GO:0040013 | 0.00 | 2.39 | 60.51 | 91 | 145 | negative regulation of locomotion | ACVRL1, ADA, ADARB1, ADORA1, AGTR2, ALOX15B, ANGPT2, APCS, APOH, ARHGAP4, ARHGDIB, BCL2, BST2, C5, KRIT1, CD63, COL3A1, CTNNA1, CX3CR1, DCN, DPEP1, DPYSL3, EPHA1, FBLN1, FCN1, GATA3, HAS1, NRG1, HRG, IFNA2, IGFBP3, IGFBP5, ILK, ITGAV, KRT16, TACSTD2, SMAD7, SERPINE1, SERPINF1, PFN2, PTGER4, PTN, PTPRJ, PTPRM, PTPRR, RAP2A, RAP2B, RRAS, CCL21, CCL25, SEMA3F, SEMG1, SHH, ST6GAL1, SP100, SRF, STAT3, STC1, NR2F2, VCL, WNT11, TRIM25, SEMA3B, RECK, FCN3, CHRD, ADAM15, RGN, ITGB1BP1, KLF4, SLIT2, SLC9A3R1, SEMA3E, PTPRU, RNF41, TRIB1, CITED2, SEMA3A, IFITM3, OLFM1, SEMA6C, SEMA6B, SEMA4F, SEMA4B, CXCL13, IFITM2, SPINT2, NRG3, IL24, ABHD2, STRAP |
1691 | GO:0034333 | 0.00 | 2.39 | 22.54 | 34 | 54 | adherens junction assembly | ACTN1, ACVRL1, ARHGAP6, BCL2, COL16A1, EFNA5, CTTN, EPHA3, GPM6B, HRG, ITGA2, JUP, KDR, LAMA5, SMAD3, SMAD7, PDPK1, PTPRJ, RAC1, S100A10, SDC4, SLC9A1, TBCD, TRIP6, TSC1, VCL, VEGFA, ARHGEF7, ITGB1BP1, TAOK2, SLK, RAMP2, SORBS1, FERMT2 |
1692 | GO:0042472 | 0.00 | 2.38 | 25.87 | 39 | 62 | inner ear morphogenesis | ALDH1A3, ATOH1, ATP2B2, ATP6V1B1, COL2A1, COL11A1, DLX5, DLX6, EPHB2, EYA1, FGF3, FGF8, FGF9, GATA3, GFI1, HMX2, HPN, INSIG1, OTX1, OTX2, PAX2, PRRX1, PROX1, PTK7, RAC1, SIX1, SOD1, SOX2, SOX9, CLRN1, WNT1, ZIC1, PAX8, FZD3, FZD6, ITGA8, HESX1, SLC9A3R1, SEC24B |
1693 | GO:0048699 | 0.00 | 2.38 | 330.99 | 486 | 797 | generation of neurons | ABL2, ACTB, ACTG1, ADAM10, ADCY1, ADCY6, ADRA2C, AP2A1, AP2B1, ALK, BIN1, ANGPT1, APBB1, APC, APOA1, APOA4, AREG, ARF1, ARF4, ARF6, ARHGAP4, PHOX2A, ARNTL, ASCL2, RERE, ATP2B2, BCHE, BCL2, PRDM1, BMP4, BMP6, BMPR1A, BMPR2, BYSL, TSPO, DAGLA, CACNA1A, CACNA1F, CACNA1S, CACNB4, CALM3, CALU, CAMK2A, CAMK2G, RUNX2, CD72, CDC20, CDC42, CDH1, CDK6, CHN1, CHRNB2, AP2M1, AP2S1, CLU, CLN5, CLTA, CNP, CNR1, CNTF, COL2A1, COL4A3, COL4A4, COL4A5, COL5A1, COL5A2, COL6A2, COL6A3, COL9A1, COL9A3, CRX, CSF2, CSF2RB, CSNK2A1, CSNK2A2, CTF1, CTNNA1, CTNNA2, CTNND2, CUX1, CX3CR1, BRINP1, DBN1, DDX6, DFNA5, DHFR, DLG1, DLG3, DLX5, DNM1, DNM2, DNMT1, DNMT3A, DNMT3B, DPYSL3, HBEGF, DTX1, ECM2, DUSP5, DUSP7, DUSP9, ECT2, S1PR1, LPAR1, EDN3, EDNRB, EFNA1, EFNA3, EFNA4, EFNA5, EFNB2, EGR2, EPHA2, EIF4E, EIF4G1, EML1, EMX1, CTTN, EMX2, EN1, EPHA1, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, ERBB2, EREG, ERCC3, ETV1, ETV4, ETV5, EVX1, EXT1, EYA1, ACSL4, EFEMP1, FGF1, FGF3, FGF6, FGF7, FGF9, FGFR3, FGFR4, GABRB2, GAK, GAP43, BLOC1S1, GDI1, GDNF, GFAP, GFI1, GFRA1, GNAT1, GNAT2, GNGT1, GOLGA4, GPC1, GRB2, RAPGEF1, GRID2, GRN, GRIN2A, ARHGAP35, HGF, HIF1A, FOXA2, HOXC10, HOXD3, HPRT1, PRMT1, HSPA8, HSP90AA1, HSP90AB1, TNC, IFNG, RBPJ, IHH, IL1B, IL2RA, IL2RB, IL2RG, ILK, ISL1, ITGA1, ITGA2, ITGA5, ITGA9, ITGAV, ITGB1, JUN, KCNA1, KIF5A, KIT, KRAS, ABLIM1, LIMK1, CAPRIN1, MAP6, MARK3, MEIS1, RAB8A, KITLG, SEPT2, SLC11A2, NRAS, NRL, NRTN, NTF3, NTF4, NTRK1, NTN3, OGN, OPA1, OPCML, OPHN1, OTX2, P2RY2, PEBP1, PARK2, PAX2, PBX1, PCP4, CDK16, SERPINF1, ATP8B1, PRRX1, PPP5C, PPT1, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK3, PSPN, KLK6, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTCH1, PTK7, PTN, PTPRA, PTPRD, PTPRM, PTPRR, RAB3A, RAB13, RAC2, RAF1, RAP1A, RAP1GAP, RAP2A, RARA, RARB, RASA2, RB1, REST, RHEB, RNF6, RPGR, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RRAS, RXRA, RYK, S100A6, S100B, SCN5A, CX3CL1, SDC2, SDC4, SDCBP, SEMA3F, SGK1, ITSN1, SHC1, SHH, SIAH1, SIAH2, SIX1, SIX3, SLC6A4, SLIT1, SLIT3, SMARCA1, SMARCD3, SNAP25, SOD1, SORL1, SOS1, SOS2, SOX3, SOX4, SOX5, SOX9, SOX10, SOX11, SPAST, SPINT1, SPTA1, SPTB, STAR, AURKA, STK11, STRN, STXBP1, SYT1, SYT4, TAL1, TBCE, DYNLT1, TNR, TP73, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TTC3, TULP1, TULP3, TYROBP, UCN, UGT8, USH2A, CLRN1, VCL, VEGFA, VEGFC, EZR, VIM, WEE1, WNT1, WNT2, WNT11, WNT2B, XK, XRCC2, YWHAG, YWHAH, RNF112, LRP8, FZD5, SEMA3B, FGF23, IFT88, RND2, SF3A2, PICALM, EOMES, FZD4, FZD7, FZD8, FZD9, CUL4B, CUL3, SEMA7A, CNTNAP1, CAMK1, KLF7, UNC5C, BECN1, PEA15, RAB11A, IQGAP1, NRP2, PROM1, KAT2B, ALDH1A2, ARHGEF7, CPNE1, RPS6KA4, KALRN, HAP1, AIFM1, CBFA2T2, ARHGEF2, VAPA, RPS6KA5, KLF4, NREP, CPNE6, SLC9A3R1, NRXN3, NRXN1, PICK1, HAND2, CHST3, ONECUT2, PSMF1, ADAMTS1, BAG5, AATK, FEZ2, RIMS2, SEMA3E, IFT140, ZNF536, SNPH, IST1, CUL7, FARP2, PSMD6, FIG4, RNF10, WDR1, RBX1, NR2E3, RANBP9, PQBP1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN2, ARPC2, FRY, AKAP9, RASA4, FARP1, PSME3, OLIG2, IRX5, KATNB1, IKZF1, HMG20B, HMG20A, SPON2, SEC24B, VAV3, BAIAP2, SLC9A6, CAP2, CAP1, STK25, CARM1, SEMA6C, SEMA6B, SEMA4F, SEMA4B, ARPC1A, ARFGEF1, DPYSL4, PDLIM5, RGS14, AVIL, FRS3, EHD1, SPINK5, RAB35, STMN2, CIT, IL1RAPL1, FZD10, TWF2 |
1694 | GO:0002287 | 0.02 | 2.38 | 11.27 | 17 | 27 | alpha-beta T cell activation involved in immune response | ANXA1, BCL3, CD80, CD86, GATA3, HLX, IFNG, PRKCZ, PTGER4, RARA, RELB, TNFSF4, EOMES, RIPK2, IL18R1, TNFSF18, BATF |
1695 | GO:0010657 | 0.02 | 2.38 | 11.27 | 17 | 27 | muscle cell apoptotic process | ALOX12, APOH, BNIP3, CAMK2A, CDKN2A, GNB1, GNGT1, NRG1, HMGCR, IFNG, IGF1, ILK, PDPK1, RPS6KA2, HAND2, BAG3, RAPGEF3 |
1696 | GO:0015701 | 0.02 | 2.38 | 11.27 | 17 | 27 | bicarbonate transport | AQP1, CA1, CA2, CA4, CA5A, CA6, CA7, CFTR, HBA1, HBA2, SLC26A4, RHAG, SLC4A1, SLC4A4, SLC4A8, SLC26A1, CA5B |
1697 | GO:0045685 | 0.02 | 2.38 | 11.27 | 17 | 27 | regulation of glial cell differentiation | BIN1, BMP4, EPHA4, FGFR3, HES1, IL1B, NTF3, NTRK3, RHEB, SHH, SPINT1, CNTN2, NR2E1, TP73, RNF112, WDR1, OLIG2 |
1698 | GO:0050710 | 0.02 | 2.38 | 11.27 | 17 | 27 | negative regulation of cytokine secretion | ANGPT1, ANXA1, ANXA4, APOA1, F2RL1, FBLN1, GAS6, IFNA2, IL10, TNFRSF9, SRGN, PTGER4, CX3CL1, TNFSF4, TNFRSF4, EZR, NR1H4 |
1699 | GO:0071230 | 0.02 | 2.38 | 11.27 | 17 | 27 | cellular response to amino acid stimulus | ASS1, BCL2L1, COL1A1, COL3A1, COL5A2, COL16A1, CYBA, DNMT1, DNMT3A, DNMT3B, GLRA1, GLRA2, HMGCS2, IPO5, NTRK2, RAPGEF3, RRAGA |
1700 | GO:1903312 | 0.02 | 2.38 | 11.27 | 17 | 27 | negative regulation of mRNA metabolic process | BARD1, C1QBP, CCNT1, CDK9, DYRK1A, PTBP1, SRSF4, SRSF6, SRSF7, SFSWAP, SRSF9, DHX34, RNF40, PTBP3, SAP18, SRSF10, RNPS1 |
1701 | GO:0051271 | 0.00 | 2.38 | 55.92 | 84 | 134 | negative regulation of cellular component movement | ACTN4, ACTN1, ACVRL1, ADA, ADARB1, ADORA1, AGTR2, ALOX15B, ANGPT2, APOH, ARHGAP4, ARHGDIB, BCL2, BST2, C5, KRIT1, CD63, COL3A1, CTNNA1, CX3CR1, DCN, DPEP1, DPYSL3, EPHA1, FBLN1, GATA3, HAS1, NRG1, HRG, IGFBP3, IGFBP5, ILK, KRT16, TACSTD2, SMAD7, SERPINE1, SERPINF1, PFN2, PTGER4, PTN, PTPRJ, PTPRM, PTPRR, RAP2A, RAP2B, RRAS, CCL21, CCL25, SEMA3F, SEMG1, SHH, SP100, SRF, STAT3, STC1, NR2F2, VCL, WNT11, SEMA3B, RECK, CHRD, ADAM15, RGN, ITGB1BP1, KLF4, SLIT2, SLC9A3R1, SEMA3E, PTPRU, RNF41, TRIB1, CITED2, SEMA3A, OLFM1, SEMA6C, SEMA6B, SEMA4F, SEMA4B, CXCL13, SPINT2, NRG3, IL24, ABHD2, STRAP |
1702 | GO:0045087 | 0.00 | 2.37 | 138.05 | 207 | 337 | innate immune response | ABL2, ACTB, ACTG1, ADARB1, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADRBK1, ANG, ANGPT1, ANXA1, APCS, ART1, ASS1, AXL, BAD, BCL2, BCL2L1, BLK, BMX, C1QA, C1QB, C1QC, C1S, C3, C5, C8B, CAMK4, CAMK2A, CAMK2G, CAPZA1, CASP9, CASP10, CD3G, CD4, CD6, CD28, CD80, CD44, CD58, CD59, CDC42, CDKN1A, CEBPG, CLU, CR2, CSF2, CSF2RB, CYP27B1, CD55, DDX3X, DHX9, HBEGF, DUSP5, DUSP9, EPRS, ERBB2, F12, FCER1A, FCGR1B, FCGR2A, FGA, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FGR, FRK, GAPDH, GATA3, GRB2, GRIN2A, NRG1, HLA-DQA1, NR4A1, HSP90AA1, ICAM1, IFNG, IFNGR1, IL1RAP, IL2RA, IL2RB, IL2RG, KIT, KLRC2, KLRD1, KRT16, LIMK1, CD180, MARK3, CD46, MAP3K5, KITLG, CIITA, FOXO4, CITED1, P2RX7, PEBP1, PDE1B, CFP, PIK3CB, PIK3CG, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCG, PRKD1, PRKCQ, PRKCSH, EIF2AK2, PROS1, PTAFR, PTPRA, RAB27A, RAC1, RASA2, RPS6KB2, S100A8, S100A9, S100A12, S100B, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SFTPD, SHC1, SLAMF1, SLC11A1, SLPI, SNCA, SOS1, SPTA1, SPTB, SRMS, SRPK2, STAR, XCL2, TAC1, TRAF2, TSC2, TYROBP, UBA7, SUMO1, VIP, VTN, LAT2, TRIM25, FGF23, CUL3, STX11, PEA15, TNK1, ADAM15, IL1RL2, CD84, VNN1, TAX1BP1, KYNU, PSTPIP1, ARHGEF2, ATG5, RAPGEF2, TBKBP1, ELMO1, GAB2, RBX1, ABI1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, TRIM28, RASA4, WASF2, TNK2, CRISP3, TRIM22, SPON2, IFI30, VAV3, BAIAP2, CLEC10A, TRIM38, ARPC1A, TXNIP, FRS3, SERINC3, ADAMTS13, CORO1A, TREX1, VSIG4 |
1703 | GO:0007626 | 0.00 | 2.37 | 24.55 | 37 | 59 | locomotory behavior | ABAT, ADRA1B, ALDH1A3, APLP2, ASTN1, ATP2B2, AVP, CACNA1B, CACNA1E, CHRNB2, CHRNB4, DBH, DPP4, ETV5, GAA, GRM1, HEXB, NRG1, HPRT1, HTR2C, IDO1, KCND2, MEIS1, PDE1B, PENK, PRKCE, SEPP1, SNAP25, SOD1, STRN, TAL1, TNR, FZD4, USP2, FIG4, RCAN2, C1QL1 |
1704 | GO:0046620 | 0.01 | 2.37 | 14.61 | 22 | 35 | regulation of organ growth | CAV3, CCNB1, CXADR, FGF8, GATA4, GATA6, NRG1, HLX, RBPJ, KCNK2, PROX1, RAG2, SLC6A4, SOD1, TP73, COL14A1, WNT2, LATS1, CTDP1, AKAP6, BCL2L11, CARM1 |
1705 | GO:0050805 | 0.01 | 2.37 | 14.61 | 22 | 35 | negative regulation of synaptic transmission | ACHE, ADORA1, ARF1, BCHE, CD38, CNR2, GNAI1, GPM6B, GRIA1, GRIK3, PARK2, RAP1A, SLC6A4, SLC18A1, SNCA, SRF, STXBP1, TNR, SLC30A1, DGKI, S1PR2, PICK1 |
1706 | GO:1900076 | 0.01 | 2.37 | 14.61 | 22 | 35 | regulation of cellular response to insulin stimulus | AHSG, AKT2, CISH, GPLD1, FFAR3, IGF2, IL1B, INS, YBX1, ENPP1, PRKAA1, PRKCA, PRKCB, PRKCQ, PRKCZ, PTPN1, PTPRE, TSC1, TSC2, OGT, PIK3R3, SOCS3 |
1707 | GO:0031532 | 0.00 | 2.37 | 17.93 | 27 | 43 | actin cytoskeleton reorganization | ABL2, ANXA1, CTSV, CXADR, S1PR1, CTTN, EPS8, FGF7, FLNA, INSRR, KIT, PRKCZ, PTK7, PTPN1, RALA, RAP2A, S100A9, SHC1, EZR, CDC42BPA, S1PR2, GMFG, CDC42BPB, SEMA3E, FARP2, FRY, CAPN10 |
1708 | GO:0021675 | 0.00 | 2.37 | 17.95 | 27 | 43 | nerve development | PHOX2A, CHRNB2, CTSV, LPAR1, EGR2, FGFR3, GABRB2, HOXD3, HES1, ILK, ISL1, KCNA2, NRTN, NTF3, NTF4, NTRK1, PAX2, ATP8B1, PRKCG, RPL24, SALL1, SEMA3F, SIX1, NRP2, PHOX2B, SEMA3A, UNC13B |
1709 | GO:0045666 | 0.01 | 2.36 | 16.58 | 25 | 40 | positive regulation of neuron differentiation | ADRA2C, ATOH1, BCL2, BMP6, CRX, BRINP1, DNMT3B, ECT2, EIF4G1, ETV5, FOXA2, HOXD3, IFNG, NRCAM, PROX1, RARA, RARB, SALL1, SOX2, SOX11, WNT2, RNF112, CPNE1, PHOX2B, HMG20B |
1710 | GO:1903844 | 0.00 | 2.36 | 21.28 | 32 | 51 | regulation of cellular response to transforming growth factor beta stimulus | CAV2, CAV3, DAB2, DNM2, FBN1, ONECUT1, ING2, ITGA3, LTBP1, SMAD3, SMAD6, SMAD7, MEN1, CITED1, PDPK1, PPM1A, PPP1CA, RPS27A, SDCBP, SOX11, STK11, UBB, WNT1, LTBP4, ITGA8, NREP, ZFYVE9, ONECUT2, ADAMTSL2, CITED2, GIPC1, STRAP |
1711 | GO:0030855 | 0.00 | 2.36 | 43.06 | 65 | 105 | epithelial cell differentiation | ACADVL, AKT2, ALDOC, ANXA4, CAPN5, CASP6, CD63, CDH3, TPP1, CNN3, DAB2, DLX5, DLX6, DSP, ELF3, EREG, ERCC3, FLG, IVL, JUN, KRT2, KRT4, KRT14, KRT16, KRT84, SMAD3, MGMT, NTRK3, PGK1, PPL, PRKX, PTHLH, PTK7, SIX1, SPRR1B, SPRR2A, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3, STAT5B, TAGLN, TSG101, TST, UPK1B, UPK2, UPK3A, USH2A, VEGFA, VIL1, MADCAM1, TAGLN2, FOXN1, AKR1C3, ADAM9, SCEL, LATS1, CBFA2T2, KLF4, DHRS9, CCNO, TXNIP, SPINK5, UPK1A |
1712 | GO:0032984 | 0.00 | 2.36 | 63.43 | 95 | 152 | macromolecular complex disassembly | ADD1, APC, SHROOM2, BNIP3, CAPZA1, CAPZB, CCNB1, CFL2, EIF5A, EPS8, F2RL1, FAU, NRG1, HMGA1, HSPA8, KLC1, RPL10A, CHMP1A, PEX14, PPP1CA, RDX, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, SET, SGK1, SLN, SMARCA4, SMARCC1, SMARCC2, SMARCD3, SMARCE1, SPAST, SPTA1, SPTB, AURKA, TMOD1, VIL1, DENR, SYNJ1, RPL14, ARHGEF2, AURKB, RPL23, IST1, DNAJC6, WDR1, HDAC6, APC2, KATNB1, GAS2L1, AVIL, STMN2, SUPT16H, RPL35, TWF2 |
1713 | GO:0030595 | 0.01 | 2.36 | 16.60 | 25 | 40 | leukocyte chemotaxis | C5, CCR5, CX3CR1, CXADR, EDNRB, FCER1G, HRH1, IFNG, IL10, ITGA1, ITGA9, KIT, PDE4B, PDE4D, PIK3CG, PRKCA, S100A8, S100A9, SFTPD, SYK, VAV1, SCG2, ARHGEF5, VAV3, CORO1A |
1714 | GO:0050768 | 0.03 | 2.36 | 9.96 | 15 | 24 | negative regulation of neurogenesis | ASCL2, BMP4, BMPR1A, TSPO, CTNNA1, FGFR3, NTRK3, PCM1, PTN, SORL1, SOX11, DYNLT1, ARHGEF2, RNF10, VAX1 |
1715 | GO:0009126 | 0.00 | 2.36 | 33.29 | 50 | 80 | purine nucleoside monophosphate metabolic process | ALDOB, ALDOC, ARNT, ATP1A2, ATP6V1A, ATP6V1B1, ATP6V1B2, BAD, BPGM, TSPO, COX4I1, COX8A, COX15, CTNS, DLD, DLG1, DLG2, DLG3, ENO2, GAPDH, GPD1, GUK1, HIF1A, HK2, HSPA8, IGF1, INS, LDHA, OGDH, P2RX7, PFKFB2, PFKFB4, PGAM2, PGK1, PGK2, PGM1, PPP2R5D, PRKAA1, SDHC, SNCA, TAZ, UQCRB, UQCRC1, UQCRC2, UQCRH, OGT, COX5A, HDAC4, COQ7, ECD |
1716 | GO:0006836 | 0.03 | 2.35 | 9.96 | 15 | 24 | neurotransmitter transport | ATP1A2, DDC, GDNF, GFAP, GLUL, KCNJ10, RAB3B, SLC6A4, SLC6A6, SLC6A7, SLC6A8, SLC22A1, SLC22A3, SLC6A5, SV2B |
1717 | GO:0010629 | 0.00 | 2.35 | 53.05 | 80 | 130 | negative regulation of gene expression | A2M, ACVR1B, AKT2, ANG, BIRC3, XIAP, ATF4, BARD1, BBS2, BBS4, SERPING1, CCNB1, CCNT1, CD28, CD59, CDC42, CDK9, CDKN1A, CIRBP, CCR1, CR1, CRYAB, CTGF, CD55, DDX3X, DYRK1A, EIF2S1, EIF4E, EIF4EBP1, EIF4EBP2, EPRS, FLOT2, FYN, GAPDH, GAS1, GRB7, IGFBP5, INPPL1, EIF3E, IREB2, CAPRIN1, CD46, SERPINE1, SERPINF1, PGR, EIF2AK2, PTBP1, RPS3, RPS26, SRSF4, SRSF6, SRSF7, SFSWAP, SLIT3, SRP9, TMF1, TSC1, UCN, VEGFB, PICALM, SRSF9, EIF2B4, EIF2B3, EIF2B5, CPNE1, HAP1, SLIT2, QKI, EIF2AK3, TMEM59, RNF40, PTBP3, PRG3, IFITM3, OLFM1, GAS2L1, IGF2BP3, SRSF10, RNPS1, ERP29 |
1718 | GO:0006022 | 0.00 | 2.35 | 46.74 | 70 | 112 | aminoglycan metabolic process | AP2A1, ANGPT1, CD44, CLTC, VCAN, CSPG4, DCN, EXT1, EXT2, EXTL1, EXTL2, EXTL3, GPC4, GPC5, GALNS, B4GALT1, GPC3, GLB1, GPC1, HAS1, HAS2, HAS3, HEXA, HEXB, HGF, IDS, IDUA, IGF1, IL1B, ITIH1, ITIH2, ITIH3, ITIH4, LUM, CHST6, MKI67, OMD, OGN, OVGP1, PIM1, PTGER4, SDC1, SDC2, SDC4, SGSH, SLC9A1, UGDH, B4GALT4, B4GALT3, PGLYRP1, PAPSS2, PAPSS1, B4GALT6, B4GALT5, CHST3, HS2ST1, SDC3, SPOCK2, HS3ST3B1, HS3ST3A1, HS3ST1, ABCC5, GPC6, B3GNT3, ST3GAL6, CSPG5, SLC26A1, SLC35D2, KERA, B4GALT7 |
1719 | GO:0048469 | 0.00 | 2.35 | 30.00 | 45 | 72 | cell maturation | ABL2, ANG, AXL, BCL2, BFSP1, BRCA2, BTK, RUNX2, CBFB, CCNB1, CFTR, CLN5, DLD, EDNRB, EPHA8, EREG, GATA3, GHRHR, GNAQ, HES1, IHH, INSL3, KDR, NRCAM, OPA1, PDE3A, PPP2R1A, PRKACA, PTH1R, RAC1, RAC3, RB1, RPS6KA2, CCL21, SOX10, AURKA, CNTN2, VEGFA, FZD5, BFSP2, PICK1, FARP2, KIAA0196, IRX5, TUSC2 |
1720 | GO:0048167 | 0.00 | 2.35 | 36.72 | 55 | 88 | regulation of synaptic plasticity | ADORA1, ARF1, ATP2B2, CAMK2A, CD38, CDC20, CDK5, CTNND2, CX3CR1, DBI, DBN1, EGR2, EIF4EBP2, GFAP, GIP, GRIA1, GRIN2A, HRH1, HRH2, ITPR3, KCNJ10, KIT, KRAS, RAB8A, NTRK2, P2RX3, PRKCZ, RELN, PTN, RAB3A, RARA, S100B, SLC8A3, SNAP25, SNCA, SRF, STAR, STAU1, STXBP1, SYP, CNTN2, NR2E1, TNR, YWHAG, YWHAH, RAB11A, DGKI, PICK1, RIN1, RAPGEF2, BAIAP2, UNC13B, RGS14, GIPC1, CPLX2 |
1721 | GO:0034446 | 0.01 | 2.34 | 13.33 | 20 | 32 | substrate adhesion-dependent cell spreading | ACTN4, AXL, EFNA1, EPHA1, EPHB3, FBLN1, ILK, ITGA4, ITGAV, LAMA5, TACSTD2, RAB1A, ST6GAL1, TYRO3, FZD4, FZD7, ITGA8, ITGB1BP1, FERMT2, BVES |
1722 | GO:0050886 | 0.03 | 2.34 | 9.99 | 15 | 24 | endocrine process | AQP1, BMP6, CRY1, GALR1, GATA3, GDF9, IL1B, INHA, KISS1, KRAS, TAC1, TACR2, TMF1, UCN, FZD4 |
1723 | GO:0009199 | 0.00 | 2.34 | 45.49 | 68 | 109 | ribonucleoside triphosphate metabolic process | AK2, AK4, ALDOB, ALDOC, AMPD2, ARNT, ATP1A2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP5O, BAD, BPGM, TSPO, COX4I1, COX8A, COX15, CTNS, DLD, ENO2, GAPDH, GNAI3, GPD1, GUK1, HIF1A, HK2, HSPA8, IGF1, INS, LDHA, LDHC, OGDH, P2RX7, PFKFB2, PFKFB4, PGAM2, PGK1, PGK2, PGM1, PPP2R5D, PRKAA1, SDHC, SNCA, STAT3, SURF1, TAZ, UQCRB, UQCRC1, UQCRC2, UQCRH, OGT, COX5A, ATP5J2, HDAC4, SLC25A13, COQ7, ATP5H, ATP5L, ECD |
1724 | GO:0042102 | 0.00 | 2.34 | 23.37 | 35 | 56 | positive regulation of T cell proliferation | ADK, ANXA1, CD4, CD6, CD28, CD80, CD86, CD59, CD55, DHPS, HES1, IFNG, IGF1, IGF2, IGFBP2, IL1B, IL2RA, IL18, ITGAL, CD46, PRKCQ, XCL1, SHH, SPN, SPTA1, STAT5B, SYK, TNFSF4, ZP3, TNFSF9, RIPK2, EBI3, TNFSF13B, HHLA2, CORO1A |
1725 | GO:0046939 | 0.00 | 2.34 | 20.03 | 30 | 48 | nucleotide phosphorylation | AK2, AK4, ALDOB, ALDOC, ARNT, BPGM, DTYMK, ENO2, GAPDH, GPD1, GUK1, HIF1A, HK2, IGF1, INS, LDHA, OGDH, P2RX7, PFKFB2, PFKFB4, PGAM2, PGK1, PGK2, PGM1, PPP2R5D, PRKAA1, STAT3, OGT, HDAC4, ECD |
1726 | GO:0042531 | 0.03 | 2.34 | 10.00 | 15 | 24 | positive regulation of tyrosine phosphorylation of STAT protein | CNTF, CSF2, CTF1, FLT3, FYN, HCLS1, HES1, IFNA2, IGF1, IL13, IL18, ISL1, PTGER4, CRLF1, IL24 |
1727 | GO:0009967 | 0.00 | 2.34 | 286.37 | 420 | 693 | positive regulation of signal transduction | ABAT, ABL2, ACTN4, ACVR1, ACVR1B, ACVR2A, ACVR2B, ACVRL1, ADA, ADORA1, ADRA1B, ADRA2C, ADRB2, AKT2, ALK, ALOX15B, ANGPT1, APC, BIRC3, XIAP, APOA1, ARHGAP4, ARHGAP6, ARNTL, ATM, ATP6AP1, ATR, BMP1, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, BST2, C1QBP, C3, C5, CALM3, CAMK2A, CAMK2G, CASP10, CAT, CAV2, CBL, CD4, CD8A, CD28, CD80, CD36, CD40, CD44, CD63, CDC42, CDKN2A, CFTR, CHI3L1, CHN1, CHN2, CHUK, CCR1, CNTF, COL1A1, COL3A1, CSF2, CSF2RB, CSNK1D, CSNK1G2, CSNK2A1, CSPG4, CTF1, CTGF, CTH, CYBA, CYP27B1, DAB2, DCN, GADD45A, DDX5, DLX5, HBEGF, DUSP5, DUSP7, DUSP9, GPR183, ECM1, ECT2, EDA, LPAR1, EDN3, EDNRA, EFNA1, EMP2, EPHA4, EPHA8, EPS8, ERBB2, EREG, ERCC6, ERN1, ESR1, EVC, EYA1, F2R, F2RL1, F3, F7, F10, FCER1A, FGA, FGF1, FGF3, FGF6, FGF7, FGF8, FGFR3, FGFR4, FGG, FGR, FOXD1, FLNA, FLT3, FLT4, FPR1, FSHR, FYN, GATA3, GATA4, GATA6, GCG, GDF9, GIP, GPC3, GNAS, GPR27, GPX1, GRB2, GRB7, RAPGEF1, GRIN2A, GRM1, GSTM2, HCLS1, HGF, NRG1, HHEX, HIC1, HMGCR, FOXA2, PRMT1, HES1, HTR2C, ICAM1, IFNA2, IFNG, IGF1R, IGF2, RBPJ, IHH, IL1A, IL2RA, IL2RB, IL2RG, IL10, IL13, IL18, ILK, ING2, INHA, INS, IRAK1, IRAK2, ISL1, ITGA1, ITGAL, ITGB1, ITPKB, JUN, JUP, KCNN4, KDR, KISS1, KIT, KRAS, LTF, CD180, MARK3, MAP3K5, MEN1, KITLG, MAP3K11, CITED1, NRAS, NTF3, NTRK1, NTRK2, NTRK3, NTSR1, TNFRSF11B, P2RX3, P2RX4, P2RX7, P2RY1, PEBP1, PDE6G, PDE6H, PF4, PHB, PIK3CB, PIK3CG, PRRX1, PPM1A, PPP5C, PRKAA1, PRKCA, PRKCE, PRKD1, PRKCQ, PRKCZ, MAPK3, EIF2AK2, RELN, KLK6, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTGER4, PTGIS, PTPN1, PTPN6, PTPRA, PTPRJ, RAC1, RAF1, RAP1A, RASA2, RFNG, RHEB, RPS27A, RYK, S100A4, S100A12, S100A13, S100B, SALL1, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDCBP, SELP, SFRP4, SH3BGR, SH3BGRL, SH3BP2, ITSN1, SHB, SHC1, SHH, SKP2, SLA, SLAMF1, SLC9A1, SLC12A1, SLC20A1, SMARCA4, SOS1, SOS2, SOX2, SOX4, SOX9, SOX11, SPTA1, SPTB, STAT3, STK11, XCL2, SYK, CNTN2, TNFRSF1A, TNFRSF1B, NR2C1, TRIP6, TNFRSF4, UBE2V1, UBE3A, WNT2, WNT11, WNT2B, ZIC2, TRIM25, ZP3, FZD5, ARHGEF5, STAM, SHOC2, FGF23, FZD4, FZD7, FZD8, CUL3, IRS4, SEMA7A, CNTNAP1, ITGA8, IKBKG, MAPKAPK5, MADD, TNFSF11, AKR1C3, PDE5A, TNKS, BECN1, TNFSF14, ADAM9, TNFRSF6B, TNFRSF18, IL18R1, HDAC3, BUD31, TNFSF18, HAP1, DGKI, BMP15, VAPA, CRLF1, ITGB1BP1, GPR55, S1PR2, TAOK2, NRXN1, GSTO1, HAND2, AKAP6, PSMF1, ADAMTS3, LITAF, GDF15, BAG4, CARTPT, TRAF4, RAPGEF2, PUM1, RIMS2, USP34, RASSF2, ZEB2, PSMD6, TNFSF15, RBX1, FGFBP1, HDAC6, SH2B3, FRAT1, SH2D3C, SH2D3A, AKAP9, RASA4, ATP6AP2, SORBS3, PSME3, TRDN, TRIM22, ABCA7, CITED2, VAV3, TRIM38, STK25, UNC13B, ARL6IP5, AGR2, ARFGEF1, SORBS1, SH2B2, HEXIM1, TRIM16, KHDRBS1, RRAGA, GRAP, GIPC1, TRAF3IP2, STARD10, FRS3, MALT1, EDAR, COPS8, ERP29, IL24, RBPMS, PIM2, ESM1, MAP4K5, FZD10, PTGDR2, PHB2 |
1728 | GO:0043065 | 0.00 | 2.33 | 84.40 | 126 | 204 | positive regulation of apoptotic process | ADRB2, AES, ALDH1A3, ALOX12, BIN1, ANXA1, ANXA5, APBB1, APC, ARHGAP4, BARD1, BCL2A1, BMP4, BNIP3L, BOK, TSPO, C1QBP, CAMK2A, CCK, TNFRSF8, CD40, CDK4, CDKN2A, CNR1, COL4A3, CRYBA1, CTGF, CTLA4, GADD45A, DDX3X, DFFA, DHODH, DNM2, DUSP1, ECT2, LPAR1, EEF1A2, EIF2S1, ERCC3, F2R, F3, FAP, FGD1, B4GALT1, GPLD1, GRIN2A, HIF1A, HIP1, HMGCR, HRG, PRMT2, IFNG, IGF2R, IGFBP3, IL1B, IL10, IDO1, ING2, ITGA6, IRF5, ITGB1, KNG1, LDHA, MAP3K5, SLC11A2, NTRK3, NTSR1, P2RX7, PPID, PRKCI, EIF2AK2, PTGIS, PTN, RAC1, RARB, REST, RPS6, RPS6KA2, RPS27A, RXRA, SORT1, S100B, SFRP4, ITSN1, SLC9A1, SMPD1, SNCA, SOS1, SOS2, SOX4, TOP2A, TRIO, VAV1, VDR, TRPV1, WNT11, FOSL1, NSMAF, KLF11, UNC5C, AKR1C3, RIPK2, TSC22D1, ALDH1A2, ARHGEF7, KALRN, LATS1, ARHGEF2, SLIT2, ARHGEF6, RAPGEF2, RASSF2, ARHGEF17, TNFSF15, CASP8AP2, PDCD6, BCL2L10, SAP18, VAV3, ATG7, ARL6IP5, TXNIP, RNPS1, CAPN10, CHEK2, AKAP13 |
1729 | GO:0015991 | 0.03 | 2.33 | 10.02 | 15 | 24 | ATP hydrolysis coupled proton transport | ATP1A2, ATP12A, ATP4A, ATP5G1, ATP5G2, ATP5G3, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, ATP6V0E1, ATP6V0D1, ATP6V1F |
1730 | GO:0032781 | 0.03 | 2.33 | 10.02 | 15 | 24 | positive regulation of ATPase activity | ADRB2, ALDOB, ATP1B3, DNM2, PFN1, PFN2, RAB3A, RAB4A, RYR2, SETMAR, TNNT2, SUMO1, RGN, ABCA7, RAPGEF3 |
1731 | GO:0035306 | 0.03 | 2.33 | 10.02 | 15 | 24 | positive regulation of dephosphorylation | ADORA1, AGTR2, CALM3, GPLD1, IFNG, ITGA1, ITGA2, SMAD3, PPP1R12A, PAWR, PPP1R7, SMPD1, SYMPK, RGN, AKAP6 |
1732 | GO:0051148 | 0.03 | 2.33 | 10.02 | 15 | 24 | negative regulation of muscle cell differentiation | BMP4, CAV3, EREG, IL18, FOXO4, YBX1, PTBP1, SHH, SOX9, CSRP3, CFLAR, HDAC3, CTDP1, CXCL14, HDAC4 |
1733 | GO:1901222 | 0.03 | 2.33 | 10.02 | 15 | 24 | regulation of NIK/NF-kappaB signaling | ACTN4, CHI3L1, IRAK1, EIF2AK2, RPS3, TRAF2, IKBKG, TNFRSF10B, TNFRSF10A, CPNE1, TRAF4, RASSF2, TNFSF15, MALT1, COPS8 |
1734 | GO:0007167 | 0.00 | 2.33 | 61.50 | 93 | 154 | enzyme linked receptor protein signaling pathway | ACVR1, ACVR1B, ACVR2A, ACVR2B, ACVRL1, AMHR2, XIAP, BMP1, BMP4, BMP6, BMP8B, BMPR1A, CAV3, CCNC, CCNT1, CCNT2, CDK8, CDK9, COL3A1, CTF1, DAB2, DLX5, DNM2, E2F4, E2F5, ETV2, FBN1, FOXD1, FNTA, FUT8, GAS6, GATA4, GATA6, GDF9, GPC3, GUCA1B, GUCY2C, GUCY2F, GUCY2D, ONECUT1, HPGD, HES1, ILK, ING2, INHA, ITGA3, ITGB5, JUN, JUNB, LTBP1, LTBP2, SMAD1, SMAD3, SMAD6, SMAD7, MEN1, CITED1, SERPINE1, PPP1CA, RBL1, RYR2, SHH, SOX11, SP1, T, KLF10, TRPS1, UBE2D1, VIM, ZIC2, ZNF8, USP9X, USP9Y, LTBP4, ITGA8, CHRD, ADAM9, AKAP4, BMP15, NREP, CER1, ZFYVE9, ONECUT2, GDF15, ADAMTSL2, ZFYVE16, FSTL3, CITED2, RBM14, GIPC1, FERMT2, RBPMS, STRAP |
1735 | GO:0048592 | 0.00 | 2.33 | 25.42 | 38 | 61 | eye morphogenesis | SHROOM2, AQP1, AQP5, BBS4, BCL2, PRDM1, BMP4, CNTF, COL5A1, COL5A2, CRYGB, EPHA2, FGFR3, GNAT1, GNAT2, GNGT1, MEIS1, NRL, NTRK2, OTX2, PRKCI, PTN, PTPRM, RPGR, RS1, SOX1, SOX2, SOX9, STAT3, TULP1, VEGFA, WNT2, WNT2B, BCAR3, PROM1, NR2E3, IRX5, IKZF1 |
1736 | GO:0014074 | 0.02 | 2.33 | 11.99 | 18 | 29 | response to purine-containing compound | ADSS, CCNE1, DGKQ, HIF1A, HMGCS1, IL1B, KCNJ11, P2RX3, P2RX4, P2RX7, P2RY2, P2RY11, SELL, SLC6A4, SOD1, TRPC3, TRPV1, CIB2 |
1737 | GO:0010770 | 0.00 | 2.32 | 18.71 | 28 | 45 | positive regulation of cell morphogenesis involved in differentiation | BMPR2, COL1A1, DAB2, EFNA5, GDNF, GOLGA4, NRG1, LIMK1, SMAD3, NTRK2, NTRK3, PAX2, SERPINB3, SDCBP, SNAI1, SRF, STK11, TWIST1, VEGFA, PAX8, RND2, SEMA7A, RAB11A, SLIT2, IST1, OLFM1, STK25, TWF2 |
1738 | GO:0051247 | 0.00 | 2.32 | 300.80 | 439 | 725 | positive regulation of protein metabolic process | ABL2, ACVR1, ACVR1B, ACVR2A, ACVR2B, ACVRL1, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADORA1, ADRA1B, ADRA2C, ADRB2, AGTR2, AKT2, ALK, ALOX12, ANG, ANGPT1, ANXA2, BIRC3, XIAP, ARNT, ATM, ATP6AP1, AVP, AVPR2, BAD, BAX, CCND1, BCL2, BCL3, BID, BMI1, BMP1, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, BOK, BRCA1, C1QBP, C3, C5, CALM3, CAMK2A, CAMK2G, CASP8, CASP9, CAV2, CCK, CCNC, CCND3, CCNH, CCNT1, CCNT2, CD4, CD14, CD28, CD80, CD86, TNFRSF8, CD36, CD40, CD44, CD74, CDC6, CDC42, CDK4, CDK5, CDK9, CDKN1A, CDKN2A, CEBPG, CENPE, CHI3L1, CIRBP, CCR1, CNTF, COL4A3, CR1, CREBL2, CSF2, CSF2RB, CSPG4, CTF1, CTGF, DAZ1, ACE, GADD45A, DDX3X, DLG1, DNMT1, DNMT3B, HBEGF, DUSP5, DUSP7, DUSP9, DYRK1A, GPR183, ECT2, LPAR1, EDN3, EDNRA, EDNRB, EEF2, EFNA1, EFNA5, EIF5A, ELAVL1, EMP2, EPHA4, EPHA7, EPHA8, ERBB2, EREG, ERCC6, ERN1, ESR1, F2R, F2RL1, F3, F12, ACSL1, FBLN1, FCER1A, FGA, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FGG, FLT1, FLT3, FLT3LG, FLT4, FNTA, FPR1, FSHR, FYN, GAS6, GCG, KAT2A, GDF9, GOLGA2, GRB2, RAPGEF1, GRIN2A, GRM1, HIST1H1B, HCLS1, HGF, NRG1, HIP1, UBE2K, HMGCR, HPN, HPX, PRMT1, HES1, HSPB1, HSP90AB1, HTR2C, ICAM1, IFI16, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGF1, IGF1R, IGF2, IGFBP3, IL1A, IL2RA, IL2RB, IL2RG, IL13, IL18, ILK, INHA, INS, IRAK1, IRAK2, IRF1, ISL1, ITGA1, ITGA2, ITGA5, ITGB1, JARID2, JUN, KDR, KISS1, KIT, KLKB1, KRAS, LTF, SMAD3, MARK3, MAP3K5, KITLG, MAP3K11, PPP1R12A, SLC11A2, NRAS, NTF3, NTRK1, NTRK2, NTRK3, DDR2, TNFRSF11B, P2RX7, P2RY1, PEBP1, PAWR, PCOLCE, PDE6G, PDE6H, ENPP2, PDPK1, PFN2, PHB, PIK3CB, PIM1, PIK3CG, PPP1R7, PPP5C, PRKAA1, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCE, PRKD1, PRKCQ, PRKCZ, MAPK3, MAPK8, EIF2AK2, DNAJC3, PROX1, RELN, PTAFR, PTGER4, PTPN1, PTPRA, PTPRZ1, RAB1A, RAC1, RAF1, RAP1A, RAP2A, RAP2B, RASA2, RBM3, REST, RPS3, RPS4X, RPS6KB2, RXRA, RYK, S100A8, S100A9, S100A12, SERPINB3, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SDCBP, SEMG1, SHC1, STIL, SKP2, SLAMF1, SLC11A1, SNAI2, SMPD1, SNCA, SOD1, SOS1, SOX2, SOX4, SPN, SPTA1, SPTB, SREBF1, STAT5B, STK10, STK11, XCL2, SYK, TARBP2, CNTN2, CLEC3B, TNFRSF1A, TP73, TPD52L1, TRAF2, TNFRSF4, UBE2L3, UBE3A, UCN, NR1H2, VEGFA, VEGFB, VEGFC, VTN, WFS1, WNT1, WNT11, ZP3, LRP8, FZD5, AIMP2, ARHGEF5, FGF23, CDK2AP1, SYMPK, PICALM, FZD4, FZD7, FZD8, BCAR3, OGT, SEMA7A, IKBKG, CAMK1, MAPKAPK5, CDC14B, MADD, TNFSF11, PDE5A, PEA15, TRADD, EED, RIPK1, CRADD, TNFSF10, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10B, TNFRSF10A, IQGAP1, CFLAR, HDAC3, KAT2B, EIF2B5, BCL10, CDK5R2, RPS6KA4, TNFSF18, LATS1, AIFM1, ARHGEF2, BMP15, VAPB, CRLF1, RPS6KA5, ITGB1BP1, GPR55, S1PR2, KLF4, TAOK2, EIF2AK3, AKAP6, GDF15, BAG4, CARTPT, TRAF4, RAPGEF2, SLK, HDAC4, RASSF2, IST1, RB1CC1, ZEB2, OXSR1, TNFSF15, RBX1, CASP8AP2, ABI1, PDCD6, BCL2L10, BCL2L11, TOM1L1, RAD50, AKAP9, EBI3, RASA4, SORBS3, TNK2, ABCA7, KLF2, PRG3, PIAS3, RAPGEF3, MAD2L2, STK25, ARL6IP5, ARFGEF1, USP16, KHDRBS1, NRG3, FRS3, RUVBL2, ARID5A, MALT1, JTB, COPS8, ERP29, IL24, RBPMS, ADRM1, GLMN, MAP4K5, RASSF1, CHEK2, FZD10, PHB2 |
1739 | GO:0008284 | 0.00 | 2.32 | 127.13 | 189 | 309 | positive regulation of cell proliferation | ADA, ADAM10, ADK, ADRB2, AGTR2, ALDH3A1, ANXA1, BIRC5, AREG, ARHGAP5, STS, ATF3, AVP, AVPR2, BCL2, BCL2L1, CAPN1, CAV3, RUNX2, CCK, CD4, CD6, CD28, CD80, CD86, CD38, CD40, CD59, CDC20, CDX2, CGA, CHRM1, CHRNB2, CLU, CNTF, CLDN7, CSF2, CSNK2A1, CTF1, CTGF, CX3CR1, CD55, DHPS, DLG1, DPP4, GPR183, S1PR3, EDN2, EDN3, EDNRA, EDNRB, EGR4, EIF5A, EMP2, EPHA1, ETS1, F2R, EFEMP1, FGF3, FGF6, FGF8, FGFR4, FLT3, FLT3LG, GDF9, GDNF, GHRH, GHRHR, HCK, HCLS1, HGF, HLX, HMX2, HOXC10, HES1, TNC, IFNG, IGF1R, IGF2, IGFBP2, IL1B, IL2RA, IL12RB2, IL18, ILK, INS, INSL3, ISL1, ITGAL, ITGAV, ITGB1, KCNA5, KIT, KRAS, LTF, EPCAM, CD46, MFGE8, KITLG, YBX1, NTF3, NTRK2, NTRK3, ODC1, PBX1, PGGT1B, PRRX1, PRKAA1, PRKCQ, PRKCZ, PTGER4, PTHLH, PTH1R, PTPN6, PURA, RAC2, RAD51B, RARA, RARB, REG1A, RPS4X, RSU1, S100A13, S100B, TSPAN31, SERPINB3, CLEC11A, CXCL5, XCL1, SDCBP, SHMT2, ST6GAL1, SIX1, SLAMF1, SMARCD3, SOX2, SOX4, SOX10, SPN, SPTA1, SRPK2, SSR1, STAT3, SYK, T, TAC1, NR2E1, TNFSF4, TNFRSF4, VIPR1, CNBP, ZNF16, ZP3, FZD3, FOSL1, CUL4A, CUL3, CDK13, AKR1C3, CHRD, SERPINB7, TNFSF13, TNFSF9, RIPK2, TSC22D1, ALDH1A2, CDC123, PRC1, CCPG1, CRLF1, ITGB1BP1, S1PR2, CNOT8, GLP2R, CIAO1, GAB2, FGFBP1, EBI3, VAV3, CARM1, MAB21L2, STAMBP, TNFSF13B, SIX2, PRDX3, IL24, ESM1, HHLA2, CORO1A |
1740 | GO:0030216 | 0.00 | 2.32 | 25.46 | 38 | 61 | keratinocyte differentiation | ALOX15B, ANXA1, CDC42, CDH3, CYP27B1, DNASE1L2, DSP, EPHA2, EREG, FLG, SFN, RBPJ, IVL, KRT2, KRT16, KRT84, REG3A, PPL, SRSF6, SPRR1B, SPRR2A, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3, ST14, TSG101, VDR, MADCAM1, FOXN1, TP63, AKR1C3, ADAM9, SCEL, LATS1, TRIM16, TXNIP |
1741 | GO:0019693 | 0.00 | 2.32 | 50.87 | 76 | 123 | ribose phosphate metabolic process | ALDOB, ALDOC, ARNT, ATP1A2, ATP2B2, ATP6V1A, ATP6V1B1, ATP6V1B2, BAD, BPGM, TSPO, CACNB4, COX4I1, COX8A, COX15, CTNS, DLD, DLG1, DLG2, DLG3, ENO2, GAPDH, GPD1, HIF1A, HK2, HMGCR, HSPA8, IGF1, INS, LDHA, OGDH, P2RX7, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, ENPP1, PF4, PFKFB2, PFKFB4, PGAM2, PGD, PGK1, PGK2, PGM1, PPP2R5D, PRKAA1, RPE, SDHC, SNCA, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, SULT2A1, TAZ, UQCRB, UQCRC1, UQCRC2, UQCRH, VEGFA, OGT, PDE5A, COX5A, ENTPD4, HDAC4, COQ7, RAPGEF3, PDE10A, ECD |
1742 | GO:0097190 | 0.00 | 2.32 | 48.08 | 72 | 117 | apoptotic signaling pathway | ADORA1, ANXA6, XIAP, ARHGAP4, ATF4, ATM, ATP2A1, BCL3, BNIP3L, BRCA2, BTK, CASP4, CD5, CD28, TNFRSF8, CD38, CD40, CDKN1A, DDX5, E2F2, ECT2, EPHA2, EP300, ERCC6, ERN1, FGD1, HIC1, HIP1, UBE2K, IFI16, ITPR1, MAP3K5, TNFRSF11B, P2RX4, PAWR, SRGN, PRKCA, PTGIS, RAC1, DPF2, RPS27A, ITSN1, SHH, SMPD2, SOS1, SOS2, SPN, SSTR3, STK11, TRIO, TNFRSF4, VAV1, XPA, CUL5, DYRK2, CUL4A, CUL3, CUL2, CUL1, TNFRSF6B, ARHGEF7, SGPL1, KALRN, AIFM1, ARHGEF6, ARHGEF17, PDCD6, VAV3, STK25, ARL6IP5, CHEK2, AKAP13 |
1743 | GO:0016331 | 0.00 | 2.32 | 37.56 | 56 | 90 | morphogenesis of embryonic epithelium | ALDH1A3, BBS4, BMP4, CASP8, FGF8, GATA3, KAT2A, GDNF, ARHGAP35, GRSF1, HHEX, HIF1A, LAMA5, LLGL2, OPA1, PAX2, PCDH8, PFN1, PRKACB, PTCH1, PTK7, RALA, RARA, SALL1, SDC4, SHH, STIL, SIX1, SOX4, SOX9, SOX11, SPINT1, ST14, T, TSC1, TSC2, TULP3, TWIST1, KDM6A, VEGFC, WNT2, WNT2B, ZIC2, PAX8, FZD3, FZD6, TP63, ALDH1A2, BCL10, HAND1, ZEB2, COQ7, SEC24B, DEAF1, SPINT2, GLMN |
1744 | GO:0051495 | 0.01 | 2.32 | 15.38 | 23 | 37 | positive regulation of cytoskeleton organization | APOA1, CCNB1, CFL2, CTGF, LPAR1, EPHA1, F2RL1, LIMK1, SMAD3, P2RX7, PFDN2, PRKCQ, PROX1, S100A10, SDC4, TAC1, WNT11, ARHGEF5, BECN1, ITGB1BP1, WDR1, SORBS3, SYNPO |
1745 | GO:0042035 | 0.00 | 2.32 | 22.12 | 33 | 53 | regulation of cytokine biosynthetic process | BCL3, CD4, CD28, CD80, CD86, TNFRSF8, CEBPG, EREG, FCER1A, GATA3, GHSR, HSPB1, IFNG, IL1A, IL1B, IL10, INHA, IRF1, PRG2, PRKCQ, PTAFR, CCL20, SFTPD, SPN, STAT5B, SYK, BCL10, KLF4, EBI3, PRG4, PRG3, IGF2BP3, GLMN |
1746 | GO:0002440 | 0.01 | 2.31 | 15.40 | 23 | 37 | production of molecular mediator of immune response | ANGPT1, APOA1, KLK3, BST2, BTK, CLC, CD55, DLG1, ERCC1, GAS6, IFNA2, IL10, KIT, SLC11A1, RNF8, EXO1, IL27RA, ATG5, TRIL, BATF, TNFSF13B, TRAF3IP2, SPINK5 |
1747 | GO:2001243 | 0.01 | 2.31 | 15.42 | 23 | 37 | negative regulation of intrinsic apoptotic signaling pathway | BCL2, BCL2L1, BDKRB2, CD44, CD74, CDKN2D, CLU, DDX3X, GCG, GRINA, ING2, OPA1, PTPN1, SNAI2, SNAI1, TPT1, VDAC2, WFS1, URI1, ARHGEF2, BCL2L10, CREB3, IVNS1ABP |
1748 | GO:0001708 | 0.01 | 2.30 | 15.43 | 23 | 37 | cell fate specification | APC, ATOH1, EVX1, GFI1, FOXA2, HOXC10, RBPJ, IHH, ISL1, ITGB1, NTRK3, OTX2, PTCH1, SHH, SIX1, SOX1, SOX2, SOX9, EOMES, FZD7, PTCH2, OLIG2, APC2 |
1749 | GO:0046165 | 0.00 | 2.30 | 20.78 | 31 | 50 | alcohol biosynthetic process | ACHE, ACLY, APOA1, APOA4, CFTR, CHKA, CHKB, CYP11B1, CYP51A1, DHCR24, CYB5R3, DPAGT1, FDFT1, FDPS, FGF7, HMGCR, HMGCS1, HMGCS2, HSD17B3, INSIG1, LCAT, PCYT1A, SQLE, STAR, CNBP, CH25H, GGPS1, CEPT1, ACAA2, EBP, C14orf1 |
1750 | GO:0032874 | 0.00 | 2.30 | 27.54 | 41 | 66 | positive regulation of stress-activated MAPK cascade | CDC42, CTGF, GADD45A, EPHA4, ERCC6, ERN1, F2RL1, FCER1A, FLT4, HMGCR, PRMT1, IL1A, IL1B, MAP3K5, MAP3K11, EIF2AK2, PTPN1, RPS3, CCL21, SDCBP, SLAMF1, SYK, TPD52L1, TRAF2, VEGFA, FZD5, ARHGEF5, FZD4, FZD7, FZD8, TNFSF11, RIPK1, RIPK2, TAOK2, TRAF4, RASSF2, ZEB2, STK25, ARL6IP5, MAP4K5, FZD10 |
1751 | GO:1902600 | 0.00 | 2.30 | 24.17 | 36 | 58 | hydrogen ion transmembrane transport | ATP1A2, ATP12A, ATP4A, ATP4B, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, COX4I1, COX5B, COX6A1, COX6A2, COX6B1, COX7A1, COX7B, COX7C, COX8A, COX15, SLC11A2, SLC9A1, SLC9A3, SLC9A5, SURF1, UQCRC1, UQCRFS1, UQCRH, ATP6V0E1, ATP6V0D1, COX7A2L, ATP6V1F, COX5A, ATP6V1G1, SLC9A6, UQCR11 |
1752 | GO:0030900 | 0.00 | 2.30 | 28.16 | 42 | 68 | forebrain development | NR0B1, APLP2, ATRX, AXL, BMPR1A, CDH1, CHRNB2, CNP, ETS1, FABP7, FGFR3, FYN, GHRH, GHRHR, ARHGAP35, HHEX, RBPJ, ISL1, KRAS, OTX1, OTX2, PCDH9, PCM1, PRKG1, PTN, RRM1, STIL, SLC6A4, SLIT1, SOX3, SSTR2, SSTR3, NR2F2, TYRO3, OGT, CHRD, HESX1, ALDH1A2, HAP1, DCLK1, OLIG2, IKZF1 |
1753 | GO:0007399 | 0.00 | 2.30 | 210.81 | 312 | 527 | nervous system development | ACHE, ACTG1, ADAM10, ADCY1, ADORA1, AP2A1, AP2B1, ALK, ANGPT1, ANXA1, APC, APLP1, APOA1, APOA4, AREG, ASTN1, BCHE, PRDM1, DAGLA, CACNA1F, CACNA1S, CACNB4, CALU, CAMK2A, CAMK2G, CASP8, RUNX2, CCK, CD72, CHRM1, CHRM3, TBCB, AP2M1, AP2S1, CLTA, COL4A3, COL4A4, COL4A5, COL5A1, COL5A2, COL6A2, COL6A3, COL9A1, COL9A3, CSF2, CSF2RB, CSNK2A1, CSNK2A2, CSPG4, CTF1, CTNND2, DFNA5, DHFR, DLG2, DLG3, DLX5, DLX6, DNM1, DNMT3A, HBEGF, ECM2, DUSP5, DUSP7, DUSP9, DYRK1A, EDN3, EDNRA, EEF2, EFNA3, EFNA4, EFNB2, EPHA2, ELAVL3, EP300, EPHA1, EPHA8, EREG, ERCC3, ETV4, ACSL4, FGF1, FGF3, FGF6, FGF7, FGF11, FGFR4, GAP43, GAS6, BLOC1S1, GFRA1, GJB1, GLRB, GNAT1, GNAT2, GNGT1, GPM6A, GPM6B, GRB2, GRIN2A, CXCL1, GSS, HLX, PRMT1, HSPA8, HSP90AA1, HSP90AB1, TNC, IHH, IL2RA, IL2RB, IL2RG, INHA, ITGA1, ITGA2, ITGA5, ITGA9, ITGAV, JUN, KIF5A, ABLIM1, LLGL2, MAP6, MARK3, RAB8A, KITLG, ATXN3, SEPT2, SLC11A2, NRAS, NRL, NTN3, OGN, OMP, OPCML, OPHN1, P2RY1, PEBP1, CNTN3, CDK16, PENK, PFN1, PPP2R5D, PPP5C, PRKCQ, PRKCZ, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPRA, PTPRM, PTPRR, PURA, RAB3A, RAB13, RAC2, RAF1, RALA, RASA2, RB1, RFNG, RPGR, RPS6KA1, RPS6KA2, RPS27A, RRAS, S100A6, SCN2B, SCN3A, SDC4, SDCBP, ITSN1, SHC1, SIAH1, SIAH2, SMARCA2, SMARCA4, SMARCC1, SMARCE1, SMPD1, SOS1, SOS2, SPAST, SPG7, SPTA1, SPTB, ST14, AURKA, STRN, STXBP1, T, TRIO, TRPC1, TRPC3, TRPC5, TSC2, TULP1, TWIST1, TYROBP, UCN, USH2A, CLRN1, KDM6A, VCL, EZR, WEE1, WNT11, FZD5, EPM2A, MAFK, FGF23, SLC7A5, DPF1, PICALM, FZD7, FZD8, FZD9, DOC2A, CUL4B, CUL3, KLF7, TP63, DCHS1, BECN1, PEA15, RGS9, IQGAP1, PROM1, ARHGEF7, BCL10, BSN, RPS6KA4, KALRN, AIFM1, VAPA, RPS6KA5, CER1, SLC9A3R1, NRXN2, PICK1, CHST3, PSMF1, FEZ2, IFT140, HDAC4, RAPGEF5, SPOCK2, FARP2, PSMD6, RBX1, NR2E3, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, FRY, AKAP9, RASA4, ATP6AP2, FARP1, PSME3, COQ7, IRX5, SIGMAR1, SPON2, VAV3, SLC9A6, CAP2, CAP1, DEAF1, CHERP, ARPC1A, ARFGEF1, DPYSL4, MAB21L2, TRIM3, SPINT2, CSPG5, FUT9, CHL1, CPLX2, FRS3, EHD1, SPINK5, RAB35, GLMN, FZD10 |
1754 | GO:0007200 | 0.02 | 2.30 | 12.08 | 18 | 29 | phospholipase C-activating G-protein coupled receptor signaling pathway | ADRA1B, BICD1, CHRM1, CHRM3, LTB4R, EDNRB, ESR1, FPR1, GNB1, GPR27, HRH1, P2RY1, P2RY2, P2RY4, P2RY6, P2RY11, PTH1R, HRH3 |
1755 | GO:0050728 | 0.00 | 2.30 | 24.21 | 36 | 58 | negative regulation of inflammatory response | ACP5, ADA, ADORA1, ADRB2, APCS, APOA1, SERPINC1, CNR2, CX3CR1, ETS1, GATA3, GHSR, GPX1, IL2RA, IL10, INS, ISL1, KRT1, SMAD3, SERPINF1, PROC, PSMB4, PTGER4, PTGIS, RPS19, SPN, TNFAIP3, TNFAIP6, TNFRSF1A, TNFRSF1B, TYRO3, PGLYRP1, SOCS3, KLF4, SLIT2, CALCRL |
1756 | GO:0008344 | 0.02 | 2.30 | 12.09 | 18 | 29 | adult locomotory behavior | ATP1A2, CLCN3, CNP, DNM1, EPS8, GDNF, GIP, FOXA2, NTF4, NTSR1, PARK2, PPT1, SNCA, TBCE, TMOD1, TSC1, PUM1, CHL1 |
1757 | GO:0061448 | 0.00 | 2.29 | 43.78 | 65 | 105 | connective tissue development | ACAT1, ACTA2, ACVRL1, BBS2, BBS4, BMP1, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, RUNX2, SERPINH1, CD44, CHI3L1, COL1A1, COL2A1, COL5A1, COL10A1, COL11A1, ATF2, CTGF, EVC, EFEMP1, FGF6, FGF9, FGFR3, FOXD1, GNAS, GPLD1, HIF1A, HMGCS2, FOXA2, HOXD3, HOXD11, IGF1, IHH, LUM, SMAD1, SMAD3, OXCT1, PRRX1, PRKCA, MAPK3, PTHLH, PTH1R, SNAI2, SNAI1, SOX5, SOX9, SRF, TRPS1, TYMS, UBB, WNT11, WNT2B, SERPINB7, DYRK1B, HAND1, EIF2AK3, HAND2, ZNF516, SIX2, ARID5A, ADAMTS7 |
1758 | GO:0051650 | 0.00 | 2.29 | 26.22 | 39 | 63 | establishment of vesicle localization | AMPH, SHROOM2, BBS2, BBS4, CACNA1A, CDH3, CDK5, DNM1, DNM2, GRN, ITGA4, OPHN1, P2RX7, PARK2, PFN2, RAB3A, RAB27A, RAB27B, RAP1A, ITSN1, SNAP25, SNCA, STXBP1, SYN1, SYT1, DOC2A, IKBKG, CADPS, STX11, RAB11A, LIN7A, SYNJ1, RAB11B, RIMS2, SNPH, RIMS3, UNC13B, CPLX2, CPLX1 |
1759 | GO:0051130 | 0.00 | 2.29 | 44.81 | 67 | 110 | positive regulation of cellular component organization | ACTN4, AHSG, ANGPT1, APOC2, AXL, ADGRB2, BICD1, C3, CBL, CD14, CD63, CDC20, CLU, COL16A1, CYBA, EPHA2, EIF5A, STOM, EPHB1, EPHB2, EPHB3, ERBB2, ACSL3, FCER1G, GAS6, GPC3, GPX1, HAS3, HIP1, HRG, IFNG, ITGAV, MFGE8, DDR2, OXT, SERPINE1, PDPK1, PPT1, PROS1, PTPRJ, RAB27A, RAP1GAP, SELE, SFRP4, SFTPD, SLC11A1, SLN, SNCA, SOX9, SYK, TPBG, TSC1, TULP1, NR1H2, EZR, VTN, SYNJ1, NRXN3, NRXN1, FRMPD4, TSPAN1, RAMP3, ABCA7, ATP8A1, AGR2, SORBS1, RER1 |
1760 | GO:0050919 | 0.02 | 2.29 | 12.10 | 18 | 29 | negative chemotaxis | APOA1, EFNA5, EPHA7, NRG1, ITGAV, RYK, SEMA3F, SLIT1, SLIT3, SEMA3B, SLIT2, SEMA3E, SEMA3A, SEMA6C, SEMA6B, SEMA4F, SEMA4B, NRG3 |
1761 | GO:0071695 | 0.02 | 2.29 | 12.10 | 18 | 29 | anatomical structure maturation | ACVRL1, RERE, CACNA1A, CDH3, S1PR1, FGFR3, GATA3, IGF1, RBPJ, LTF, PAX2, RYR1, WNT1, RECK, DCHS1, ALDH1A2, CDK5R2, SPINK5 |
1762 | GO:0010811 | 0.05 | 2.29 | 8.73 | 13 | 21 | positive regulation of cell-substrate adhesion | ARL2, ECM2, FBLN1, ITGA3, ITGA5, ITGB1, VIT, PRKCE, PTN, RSU1, VTN, SPOCK2, AGR2 |
1763 | GO:0001935 | 0.05 | 2.29 | 8.73 | 13 | 21 | endothelial cell proliferation | APOA1, APOH, KRIT1, SCARB1, DLG1, ERN1, PIK3CB, PRKX, PTPRM, SPARC, NR2F2, ALDH1A2, ITGB1BP1 |
1764 | GO:0060538 | 0.00 | 2.29 | 35.06 | 52 | 84 | skeletal muscle organ development | ADRB2, ARNTL, ASS1, ATF3, BCL2, BCL9, KLF5, CACNA1S, CAV2, CDK5, COL19A1, DCN, DDX5, TSC22D3, EEF2, EGR2, EMD, EP300, GPC1, GPX1, HLF, HLX, HMGCR, IGFBP5, MEOX2, NRAS, PRKAA1, RB1, RYR1, S100B, SHH, SIX1, SOX11, SVIL, TAZ, NR2F2, TWIST1, XK, CSRP3, EOMES, SAP30, CFLAR, PHOX2B, USP2, GTF3C5, HDAC4, NR1D2, HMG20B, VAMP5, USP19, VAX1, BVES |
1765 | GO:0043903 | 0.00 | 2.29 | 45.88 | 68 | 110 | regulation of symbiosis, encompassing mutualism through parasitism | ADAR, ADARB1, APCS, BAD, BCL2, BST2, CAV2, CCNH, CCNT1, CD28, CDK9, CHD1, DDB1, DDX3X, DDX5, EP300, STOM, ERCC3, F2RL1, FBLN1, FCN1, GTF2F1, HPN, IFI16, IFIT1, IFNA2, ISG20, ITGAV, JUN, LTF, OAS1, OAS3, PARK2, PPIB, PPID, EIF2AK2, PROX1, REST, SLPI, SMARCA4, SP1, SP100, SRPK2, SSRP1, STAU1, SUPT4H1, TARBP2, DYNLT1, TMPRSS2, TOP2A, TSG101, TRIM25, RAB7A, FCN3, OASL, CTDP1, VAPB, VAPA, BCL2L11, TRIM28, TNIP1, IFITM3, PPIE, PPIH, TRIM38, IFITM2, SUPT16H, SNF8 |
1766 | GO:0007517 | 0.00 | 2.29 | 19.48 | 29 | 47 | muscle organ development | ACHE, AEBP1, CCNB1, CENPF, CHD2, COL6A3, CRYAB, CTF1, HBEGF, EFNB2, EGR3, ETV1, EVC, GATA4, GATA6, IGF1, ITGA7, LAMA5, SMAD3, FOXO4, SCN8A, SGCB, SGCD, TAGLN, COL14A1, SGCE, AKAP6, FAM65B, SPEG |
1767 | GO:0010951 | 0.00 | 2.28 | 62.18 | 92 | 149 | negative regulation of endopeptidase activity | A2M, SERPINA3, AHSG, AKT2, AMBP, BIRC3, XIAP, BIRC5, APLP2, AQP1, SERPINC1, AVP, BST2, SERPING1, C3, C5, CASP8, SERPINH1, CD44, CDKN2D, COL4A3, COL6A3, CR1, CRYAB, CSNK2A1, CST1, CST6, DDX3X, DHCR24, DPEP1, SERPINB1, IFI6, GAS6, SFN, GPX1, SERPIND1, HGF, HRG, IFI16, ITIH1, ITIH2, ITIH3, ITIH4, KNG1, PEBP1, SERPINE1, PAX2, SERPINA5, SERPINF1, PI3, SERPINB6, SERPINB8, SERPINB9, SERPINB10, SERPINI1, SERPINB13, PROS1, PZP, RAF1, RAG1, RPS6KA1, RPS6KA3, SERPINB3, SERPINB4, SIAH2, SLPI, SNCA, SORL1, SPINK1, SPINT1, SERPINA7, TRAF2, VEGFA, VIL1, VTN, PICALM, RECK, SERPINB7, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR, USP14, KLF4, PSMF1, SPINT2, SPINT3, PRDX3, SPINK5 |
1768 | GO:0051962 | 0.00 | 2.28 | 90.14 | 133 | 216 | positive regulation of nervous system development | ABL2, ADRA2C, BIN1, APBB1, ARF1, ATOH1, ADGRB2, BCL2, BMP4, BMP6, BMPR2, TSPO, CDC20, CNR1, CRX, CUX1, CX3CR1, BRINP1, DNMT3B, DPYSL3, ECT2, LPAR1, EFNA5, EIF4G1, EPHA3, EPHA4, EPHB1, EPHB2, EPHB3, ETV5, FYN, GFAP, GOLGA4, RAPGEF1, GRN, ARHGAP35, HGF, NRG1, HIF1A, FOXA2, HOXD3, HES1, IFNG, IGF1, IL1B, ILK, ITGA3, ITGB1, KIT, LIMK1, CAPRIN1, NRCAM, NTF3, NTRK1, NTRK2, NTRK3, OPA1, OXT, P2RY2, PARK2, PAX2, PCP4, SERPINF1, PRKCI, PRKD1, PROX1, RELN, PTK7, PTN, PTPRD, PTPRZ1, RAP1A, RARA, RARB, RHEB, SALL1, CX3CL1, SGK1, SHH, SMARCD3, SOX2, SOX10, SOX11, SPINT1, SRF, STAR, CDKL5, STK11, SYT1, SYT4, TP73, TPBG, VEGFA, VEGFC, WNT2, XRCC2, RNF112, LRP8, FZD3, RND2, SF3A2, SEMA7A, CAMK1, NUMB, RAB11A, KAT2B, CPNE1, PHOX2B, HAP1, CBFA2T2, NUMBL, SLIT2, CPNE6, NRXN3, NRXN1, ADAMTS1, RAPGEF2, RIMS2, IST1, CUL7, FIG4, RNF10, OLIG2, KATNB1, HMG20B, SEMA3A, BAIAP2, STK25, RGS14, AVIL, STMN2, IL1RAPL1, TWF2 |
1769 | GO:0002520 | 0.00 | 2.28 | 173.32 | 254 | 416 | immune system development | ABL2, ACP5, ACTN1, ACVR1B, ACVR2A, ADA, ADD1, ALAS2, ANGPT1, ANXA1, ANXA2, APC, APCS, RHOH, ARNT, ATP6AP1, AXL, BAD, BAX, BCL2, BCL3, BGLAP, PRDM1, BMI1, BMP4, BMX, BRCA2, ZFP36L2, BTK, C1QC, C3, CA2, CACNB4, CAMK4, CASP8, CASP9, CASP10, RUNX2, CBFB, CBLB, CD2, CD3D, CD4, CD8A, CD80, CD86, TNFSF8, CD74, CDC42, CDK6, CDKN2A, CEBPE, CEBPG, CHD2, CHUK, CLC, CCR1, CR2, CSF2, CTLA4, CYLD, ACE, DNASE2, DTX1, GPR183, EEF2, EGR3, EPHA2, EML1, EP300, EPB42, EPHB3, ERBB2, ETS1, ETV2, ETV6, F2RL1, FCER1G, FECH, FGF3, FLI1, FLT3, FLT3LG, FSHR, GABPA, GAS6, GATA3, GFI1, GPC3, GNAS, HCLS1, HHEX, HIF1A, HLX, ONECUT1, PRMT1, HES1, IFI16, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, RBPJ, IHH, IL1B, IL2RA, IDO1, INHA, IRF1, ITGA4, ITGB1, ITPKB, JARID2, JUN, JUNB, KDR, KIT, LTF, SMAD3, CD46, MEIS1, KITLG, SLC11A2, NTRK1, PAX1, PBX1, PDE1B, PF4, PIP4K2A, PRKCA, PRKCZ, MAPK3, EIF2AK2, PRKX, PTGER4, PTPN6, PTPRZ1, RAF1, RARA, RB1, ARID4A, RELB, REST, RHAG, RPL22, RPS19, RRAS, SATB1, SRSF4, SHH, SIX1, SLC8A3, SOD1, SOS1, SOS2, SOX4, SP1, SP3, SPN, SPTA1, SPTB, SRF, STAT5B, STK11, SYK, TAL1, TAZ, KLF10, TNFAIP3, TOP2A, TPD52, TSC1, TYRO3, TYROBP, VEGFA, WNT1, WNT2B, ZNF16, FZD5, HIST1H4I, PICALM, EOMES, FZD7, FZD8, FZD9, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, FOXN1, OGT, KCNAB2, PIR, AP3B1, TNFSF11, CDK13, RIPK1, TNFSF9, RIPK2, IL1RL2, IL18R1, INPP4B, ARHGEF7, VNN1, SGPL1, AP3D1, PGLYRP1, TNFSF18, KRT75, CCNB2, GPR55, KLF4, HAND2, SOX13, CARTPT, HDAC4, RASSF2, ZBTB24, GAB2, FARP2, PTBP3, ABI1, BCL2L11, SH2B3, TSPAN2, WASF2, RNF41, DHRS2, PRG4, TRIB1, LRRC17, FSTL3, IKZF1, KLF2, CITED2, ARIH2, TACC3, CXCL13, GAS2L1, KLF1, EBP, MALT1, PRDX3, SPINK5, BVES, TUSC2 |
1770 | GO:0006027 | 0.05 | 2.28 | 8.75 | 13 | 21 | glycosaminoglycan catabolic process | CD44, GPC4, GPC5, GPC3, GPC1, SDC1, SDC2, SDC4, SGSH, SLC9A1, PGLYRP1, SDC3, GPC6 |
1771 | GO:0048814 | 0.05 | 2.28 | 8.75 | 13 | 21 | regulation of dendrite morphogenesis | CDK5, CHRNB2, EFNA1, PTPRZ1, RAP2A, SDC2, STK11, NR2E1, YWHAH, RAPGEF2, PQBP1, PDLIM5, CIT |
1772 | GO:0071310 | 0.00 | 2.28 | 41.84 | 64 | 111 | cellular response to organic substance | AARS, ACADVL, ADD1, ASNA1, ATF3, ATF4, BAX, CCND1, BCL2, CACNA1E, CD9, TPP1, CTH, DDX11, EFNA5, EGR2, EIF2S1, SLC29A1, EPHA5, EXTL3, FCER1G, GPR27, HDGF, HMGCR, FOXA2, DNAJB9, ATXN3, OXCT1, CDK16, EIF2AK2, DNAJC3, PTPRN2, SLC2A5, SOX4, SRF, SSR1, SULT1A3, ABCC8, SYP, UFD1L, VSNL1, WFS1, ZNF16, ZBTB17, VAPB, RAB11B, HMGN3, NRXN1, EIF2AK3, GOSR2, CUL7, C2CD2L, CTDSP2, PREB, PDIA6, CALCRL, CREB3, AGR2, CERS1, GJB6, SEC61B, PDIA5, KDELR3, SEC63 |
1773 | GO:1901343 | 0.01 | 2.28 | 17.53 | 26 | 42 | negative regulation of vasculature development | ADRB2, ANGPT2, APOH, KLK3, ADGRB2, BMP4, KRIT1, COL4A3, CX3CR1, DCN, GTF2I, HHEX, HRG, FOXO4, SERPINE1, PDE3B, SERPINF1, PF4, PTGER4, PTN, PTPRM, SPARC, ITGB1BP1, KLF4, SEMA3E, SPINK5 |
1774 | GO:0070887 | 0.00 | 2.28 | 53.48 | 82 | 144 | cellular response to chemical stimulus | ACY1, ADAM10, ADH1B, ADH5, ALDH1A1, ALDH2, ALDH3A1, ALDH1B1, AOC2, C1QBP, C5, COMT, CRYZ, CXADR, CYP2A6, CYP2A13, CYP2F1, CYP3A4, CYP3A5, CYP8B1, CYP51A1, DDX3X, EDN3, EDNRA, EPHA2, EPHB1, ESD, ETV5, F7, FDXR, FMO3, GJB2, GPX1, GSS, GSTM1, GSTZ1, HP, ITGA1, ITGA9, MGST2, SLC11A2, PCP4, PTGS1, RAC2, RPS19, RYK, S100A8, S100A9, S100A12, SAA4, SCN3A, SFPQ, SFTPD, STAU1, SULT1E1, SULT1A1, SULT1C2, SULT2B1, SULT2A1, TPMT, TRPM2, UGDH, UGP2, UGT2B4, SCG2, ARHGEF5, CYP4F2, AOC3, CES2, VNN1, AIP, PAPSS2, PAPSS1, GSTO1, BAG5, CXCL14, DHRS2, COQ7, GLYAT, AKR1A1, ARL6IP5, SLC26A1 |
1775 | GO:0007586 | 0.00 | 2.27 | 28.35 | 42 | 68 | digestion | SERPINA3, AQP1, AQP5, CHRM1, CHRM3, CLPS, COPA, CTSE, ACE, ENPEP, FABP2, GALR1, GHSR, HRH2, HTR3A, KCNN4, MEP1A, OXT, P2RX7, PAWR, PGA5, PGC, PYY, SCTR, SGK1, SI, SLC15A1, SLC22A5, SOX9, SSTR2, SULT2A1, TAC1, TRPC1, UCN, NR1H2, VIPR1, TRPV1, MGAM, LIPG, CAPN9, STRAP, TREH |
1776 | GO:0031057 | 0.05 | 2.27 | 8.76 | 13 | 21 | negative regulation of histone modification | BRCA1, DNMT1, DNMT3B, JARID2, SET, SNCA, TAF7, TWIST1, UCN, TRIP12, ATG5, KDM4A, ATG7 |
1777 | GO:0048048 | 0.05 | 2.27 | 8.76 | 13 | 21 | embryonic eye morphogenesis | ALDH1A3, FBN1, EFEMP1, IHH, PAX2, PROX1, RARB, SIX3, SOX11, SP1, SP3, TWIST1, FZD5 |
1778 | GO:0099518 | 0.05 | 2.27 | 8.76 | 13 | 21 | vesicle cytoskeletal trafficking | ACTN4, AP3S1, DYNC1I1, BLOC1S1, PRKCZ, RAB1A, AP3B1, AP3D1, HAP1, KIF3B, AP3S2, AP3M2, KIF3A |
1779 | GO:0007601 | 0.00 | 2.27 | 55.50 | 82 | 133 | visual perception | ABCA4, AOC2, ARR3, BBS1, BBS2, BBS4, OPN1SW, CACNA1F, CACNB4, CDH3, CHRNB2, CNGA1, COL1A1, COL2A1, COL11A1, CRX, CRYBA1, CRYBA4, CRYGB, CRYZ, EYA4, EYA3, EFEMP1, GABRR2, OPN1MW, GJA3, GLRA1, GLRB, GNAT1, GNAT2, GRM8, GUCA1A, GUCA1B, GUCY2F, GUCY2D, HPS1, IMPG1, KCNJ10, ABLIM1, LUM, TACSTD2, NRL, OAT, OPA1, SIX6, PAX2, PDCL, PDC, PDE6G, PDE6H, PPT1, RABGGTA, RABGGTB, OPN1LW, RCVRN, PRPH2, RGR, RGS16, RLBP1, RPGR, RS1, SAG, ATXN7, SFRP5, SIX3, NR2E1, TULP1, TULP2, USH2A, CLRN1, WFS1, ZIC2, SOX14, BFSP2, RGS9, SLC24A1, DHRS3, GUCA1C, NR2E3, IRX5, RRH, KERA |
1780 | GO:0048513 | 0.00 | 2.27 | 185.26 | 276 | 479 | animal organ development | ACTN1, ACVR2A, ACVRL1, ADAR, ADD1, AHR, AHSG, AKT2, ALAS2, ALDOB, AMELY, AMHR2, ANXA2, APCS, APRT, ARF6, ARHGAP5, RHOH, ASGR2, ASNS, ATP6AP1, ATP7B, BCL2L1, BCL3, BFSP1, BIK, BMI1, BMP8B, BMX, ZFP36L2, BTK, TSPO, C1QB, C1QC, CAPN5, CACNA1F, CACNB4, CAMK4, CASP9, CASP10, CBFB, CD2, CD3D, CD4, CD8A, CD28, CD80, CD86, TNFSF8, CD74, CDKN2A, CDO1, CEBPE, CEBPG, CLCN2, CCR1, COL9A3, CPS1, CR2, CRYBA1, CRYBA4, CTLA4, CYLD, DFNA5, DHODH, DNASE2, DTX1, GPR183, ECM1, SLC29A1, EPB42, ERCC3, ETV6, F2RL1, FANCA, FANCG, FCER1G, FECH, FLT3LG, CENPI, FSHR, NR5A1, GABPA, GABRB2, GDF9, GNB1, GPD2, GPLD1, GPM6A, GPM6B, HSD17B10, HCLS1, HK2, HMGCL, HRH2, PRMT1, HSD17B3, HSD17B4, ICAM1, IDH1, IFI16, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IL1B, IL2RA, IMPDH1, IMPDH2, ING2, INHA, INSL3, IRF1, ITPKB, JARID2, KCNQ1, KIT, LIM2, LUM, CD46, MEA1, MGMT, SLC11A2, NTRK1, DDR2, NTS, OMD, OTC, PDE1B, ENPP1, PF4, ATP8B1, PHEX, PHF2, PIP4K2A, PPIB, SRGN, PRKACG, PRKCA, PRKCZ, EIF2AK2, PTGER4, PTH1R, PTPN6, PTPRN, QDPR, RAB13, RAG1, RAG2, RAP1GAP, ARID4A, RBBP6, RCN1, PRPH2, RELB, RHAG, RPL22, RPL24, RPS19, RRAS, RREB1, SATB1, SRSF4, SMARCA4, SOS1, SOS2, SOX5, SP2, SPN, SPTA1, SPTB, SRY, STAT5B, STK11, KLF10, TMF1, TMOD1, CLEC3B, TOP2A, TPD52, TNFSF4, TYROBP, USF2, USH2A, VIM, ZNF16, ZP3, CSDE1, FGF23, NRIP1, HIST1H4I, PICALM, FZD8, FZD9, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, BFSP2, UTF1, CUL4A, KCNAB2, PIR, AP3B1, CDK13, RIPK1, TNFSF9, RIPK2, IL1RL2, IL18R1, INPP4B, LIN7A, NRP2, ARHGEF7, VNN1, EIF2B4, EIF2B2, EIF2B5, EIF2S2, AP3D1, PGLYRP1, TNFSF18, PAPSS2, KRT75, CCNB2, DYRK1B, BMP15, ITGB1BP1, GPR55, CXCL14, MINPP1, SOX13, CARTPT, TRAF4, IQCB1, ZNF516, VPRBP, RASSF2, ZBTB24, GAB2, FARP2, SETDB1, PTBP3, KCNE2, ABI1, SH2B3, AKAP9, WASF2, RNF41, DHRS2, PRG4, TRIB1, LRRC17, ARIH2, GPNMB, DEAF1, BATF, PRDX4, CXCL13, MAB21L2, GAS2L1, KLF1, EBP, ARID5A, MALT1, KERA, ADAMTS7, SEC63, TUSC2 |
1781 | GO:0031330 | 0.00 | 2.27 | 19.56 | 29 | 47 | negative regulation of cellular catabolic process | ADRA1B, BCL2, BCL2L1, TSPO, CNR1, DFFA, GATA4, GOLGA2, GPLD1, HGF, HP, IL10, INS, KIF25, PIK3CG, PTPN3, SNCA, SNRNP70, STAT3, TSC1, RGN, FEZ2, KDM4A, DHX34, RUBCN, HDAC4, ATG7, RRAGA, WDR6 |
1782 | GO:1901575 | 0.00 | 2.27 | 55.59 | 83 | 138 | organic substance catabolic process | ACAA1, ACADM, ACADS, ACADVL, ACHE, ACOX1, ADH5, ADORA1, ADRB2, AKT2, ABCD1, ALDOB, ALDOC, APOA1, APOA4, APOC2, APOH, BAD, BNIP2, BPGM, DAGLA, CLPS, CNR1, CPT1B, CPT2, DECR1, ECH1, EHHADH, ENO2, ESD, ETFA, ETFDH, FAAH, FABP2, FABP6, FABP7, FUT6, FUT8, GALE, GALK1, GAPDH, HADHA, HK2, HSD17B4, IDH1, KHK, LDHA, LIPA, LIPE, OXCT1, PAFAH1B2, PAFAH1B3, PAFAH2, PCCA, PFKFB2, PFKFB4, PGAM2, PGK1, PGK2, PIK3CG, PPP2R5D, PRKACB, PRKACG, PRKCE, ABCD3, RPE, SCP2, TWIST1, ACOX2, ACOX3, LIPG, PRDX6, XYLB, ACOT8, AKR1A1, ECI2, SLC25A17, SPTLC1, FUT9, SLC27A4, SLC27A2, TREH, ACOT7 |
1783 | GO:0031324 | 0.00 | 2.27 | 83.14 | 124 | 208 | negative regulation of cellular metabolic process | A2M, SERPINA3, APCS, BIRC3, XIAP, APLP2, APOA4, AQP1, SERPINC1, AVP, BST2, SERPING1, C3, C5, CASP8, SERPINH1, CCNC, CD44, CD59, CLU, COL4A3, COL6A3, COMT, CR1, CST1, CST6, CD55, DHCR24, DPEP1, ECM1, SERPINB1, FYN, IFI6, GAS1, GPC3, GPX1, SERPIND1, HRG, DNAJB2, IDE, ITGAV, ITIH1, ITIH2, ITIH3, ITIH4, KNG1, LIMK1, CD46, PEBP1, SERPINE1, PDCL, SERPINA5, SERPINF1, PI3, SERPINB6, SERPINB8, SERPINB9, SERPINB10, SERPINI1, SERPINB13, PRKCE, PROS1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC4, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PZP, RAF1, RAG1, RPS6KA1, RPS6KA3, SERPINB4, SLPI, SNTA1, SOX4, SPINT1, SERPINA7, TRAF2, UCN, USP4, VIL1, VTN, PICALM, RECK, SERPINB7, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR, PSMD6, FRY, PSME3, HMG20B, PIAS3, OLFM1, CRTAP, SPINT2, PTTG2, SPINT3, SPINK5, GLMN |
1784 | GO:0035725 | 0.00 | 2.27 | 19.58 | 29 | 47 | sodium ion transmembrane transport | SHROOM2, ATP12A, ATP4A, HCN2, SCN1A, SCN3A, SCN8A, SCN10A, SCNN1A, SCNN1B, SCNN1D, SCNN1G, SLC5A5, SLC8A1, SLC8A3, SLC9A3, SLC9A5, SLC12A3, SLC13A1, SLC20A1, SLC20A2, TRAPPC10, TRPM2, SLC4A4, SLC24A1, HCN4, SLC9A6, SLC34A2, SCN11A |
1785 | GO:0046649 | 0.00 | 2.26 | 63.53 | 94 | 154 | lymphocyte activation | ABL2, AHR, APC, RHOH, BAX, BCL3, BMX, ZFP36L2, BST2, CAMK4, CASP8, RUNX2, CBFB, CCND3, CD2, CD7, CD8A, TNFSF8, CD151, CDK6, CEBPG, CLC, CR2, CXADR, EP300, EPHB1, ERCC1, F2RL1, FCER1G, HHEX, ONECUT1, HPRT1, ICAM1, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, RBPJ, IL2RB, IMPDH1, IMPDH2, INS, ITGA4, ITGAD, ITGB1, KIT, LMO1, CD180, SMAD3, NTRK1, P2RX7, PAX1, PIK3CG, PRKCB, PSMB10, PTGER4, RAB27A, RAC2, RAG2, RELB, RPL22, SATB1, SLAMF1, SLC11A1, SOD1, SOS1, SOS2, SOX4, SP3, SRF, STK11, TPD52, TSC1, LAT2, WNT1, FZD5, EOMES, FZD7, FZD8, FZD9, FOXN1, STX11, IL18R1, RNF8, EXO1, IL27RA, SOX13, VPRBP, HDAC4, RNF41, BATF, SPINK5, TUSC2 |
1786 | GO:0032092 | 0.01 | 2.26 | 14.19 | 21 | 34 | positive regulation of protein binding | ABL2, ADD1, BMP4, KRIT1, CDK5, EP300, EPB41, GCG, HSP90AB1, ITGA2, MEN1, RAN, RFNG, SPTA1, TRAF2, VTN, ARHGEF7, TNFSF18, EIF2AK3, TRAF4, RAPGEF2 |
1787 | GO:0035567 | 0.01 | 2.26 | 14.19 | 21 | 34 | non-canonical Wnt signaling pathway | ABL2, CDC42, CSNK1D, DAB2, CELSR2, GPC4, PTK7, RAC1, RYK, SFRP4, SFRP5, WNT11, FZD5, FZD3, FZD4, FZD6, FZD7, FZD8, FZD9, GPC6, FZD10 |
1788 | GO:0043297 | 0.01 | 2.26 | 14.19 | 21 | 34 | apical junction assembly | ACTN4, APC, ARL2, CLDN3, CTNNA1, DLG1, ECT2, ITGB1, PRKACA, PRKCI, RAB13, SNAI2, SNAI1, SRF, STRN, TBCD, VCL, WNT11, FZD5, CLDN12, RAMP2 |
1789 | GO:0046530 | 0.01 | 2.26 | 14.19 | 21 | 34 | photoreceptor cell differentiation | BBS4, PRDM1, CNTF, CRX, GNAT1, GNAT2, GNGT1, IHH, NRL, NTRK2, OTX2, PRKCI, PTN, RPGR, SOX9, STAT3, TULP1, VEGFA, PROM1, IFT140, NR2E3 |
1790 | GO:0046888 | 0.01 | 2.26 | 14.19 | 21 | 34 | negative regulation of hormone secretion | ADORA1, ADRA2C, ANXA5, CRY1, GHSR, HMGCR, IL1B, INHA, KCNJ11, PARK2, PDE4C, PTGS1, REST, SREBF1, ABCC8, TACR2, UCN, VSNL1, FGF23, STXBP5L, CARTPT |
1791 | GO:0045740 | 0.00 | 2.26 | 19.61 | 29 | 47 | positive regulation of DNA replication | AREG, ATM, ATR, ATRX, BMP4, BMP6, CDC42, CSF2, EREG, IGF1, IGF1R, INS, JUN, KITLG, NVL, PRKCQ, MAPK3, RAC1, SHC1, CCT3, UCN, MAPKAPK5, TNKS, AURKB, KLF4, CCT7, CCT4, CCT2, CCT8 |
1792 | GO:0071897 | 0.00 | 2.26 | 30.46 | 45 | 73 | DNA biosynthetic process | ACVRL1, BMPR2, CDKN1A, CDKN2D, CENPF, CTGF, DDB1, DNTT, DUSP1, FGFR4, HGF, KCNK2, MEN1, NVL, PHB, PRKCQ, MAPK3, REV3L, RFC1, RFC2, RFC3, RFC4, RFC5, RPA3, RPS27A, TYMS, UBB, UBA7, UFD1L, WRN, TRIM25, CUL4B, CUL4A, MAPKAPK5, TNKS, RGN, AURKB, KLF4, KIAA0101, RBX1, MAD2L2, CCT4, CCT2, CERS1, PAPD7 |
1793 | GO:0008016 | 0.02 | 2.26 | 12.80 | 19 | 31 | regulation of heart contraction | CACNA1B, CACNA1F, CACNA1S, CACNA2D1, CACNB4, CACNG1, HBEGF, GLP1R, KCND2, KCND3, KCNJ12, KCNJ14, KCNK3, S100A1, SP4, TNNT2, KCNK6, NUP155, CACNG2 |
1794 | GO:0048588 | 0.00 | 2.25 | 40.02 | 59 | 96 | developmental cell growth | ARHGAP4, BMPR2, CDK5, DCC, DCX, DNM2, EFNA5, EMX1, CTTN, EPHA7, GDF9, GOLGA4, NRG1, PRMT2, ILK, ITGB1, LIMK1, NRCAM, NTRK3, PARK2, PRKCZ, RNF6, SEMA3F, SLIT1, SLIT3, SOX9, SRF, AURKA, CDKL5, STK11, SYT1, SYT4, TNR, VCL, VEGFA, SEMA3B, RND2, USP9X, SEMA7A, RAB11A, IQGAP1, NRP2, CPNE1, DCLK1, SLIT2, CPNE6, AATK, RIMS2, SEMA3E, IST1, SEMA3A, ARIH2, OLFM1, SLC9A6, SEMA6C, SEMA6B, SEMA4F, SEMA4B, TWF2 |
1795 | GO:1903649 | 0.02 | 2.25 | 12.83 | 19 | 31 | regulation of cytoplasmic transport | ATP1A2, BNIP3L, CYBA, DIAPH1, GAS1, HRC, PARK2, PDE4D, PRKACA, PRKCE, PRKD1, MAPK3, PTPN6, RYR2, SLC8A1, SREBF1, ATG5, SEC24B, CORO1A |
1796 | GO:0051100 | 0.03 | 2.25 | 10.83 | 16 | 26 | negative regulation of binding | IFI16, JUN, P2RY1, PLN, PEX19, RAP1GAP, SLN, SOX11, SP100, SUMO1, TNKS, CPNE1, BTAF1, HAND1, HAND2, MAD2L2 |
1797 | GO:0010721 | 0.02 | 2.25 | 12.84 | 19 | 31 | negative regulation of cell development | ACTN4, BCL2, CAV3, S1PR3, FBLN1, HPN, IGF1, LTF, TACSTD2, SMAD7, CITED1, PAX2, SALL1, TRPV1, PAX8, CTDP1, ITGB1BP1, MAD2L2, STRAP |
1798 | GO:0043534 | 0.03 | 2.24 | 10.84 | 16 | 26 | blood vessel endothelial cell migration | ACVRL1, AGTR2, ANGPT1, ANGPT2, APOA1, SCARB1, EFNA1, EPHA2, EMP2, GPX1, HRG, HSPB1, PRCP, PRKCA, PRKD1, VEGFC |
1799 | GO:0016525 | 0.01 | 2.24 | 16.28 | 24 | 39 | negative regulation of angiogenesis | ADRB2, ANGPT2, APOH, KLK3, ADGRB2, KRIT1, COL4A3, CX3CR1, DCN, GTF2I, HHEX, HRG, FOXO4, SERPINE1, PDE3B, SERPINF1, PF4, PTN, PTPRM, SPARC, ITGB1BP1, KLF4, SEMA3E, SPINK5 |
1800 | GO:0032091 | 0.01 | 2.24 | 16.28 | 24 | 39 | negative regulation of protein binding | ADRB2, AES, ANXA2, BAX, DAB2, GOLGA2, IFIT1, IL10, ISL1, ITGA4, LRPAP1, PEX14, PPP1CA, MAPK3, MAPK8, SLPI, SORL1, AURKA, CAMK1, ADAM15, AURKB, ITGB1BP1, CARM1, RUVBL2 |
1801 | GO:0033046 | 0.01 | 2.24 | 16.28 | 24 | 39 | negative regulation of sister chromatid segregation | APC, ATM, ATRX, BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DUSP1, MAD2L1, UBE2D1, ZNF207, TNKS, CDC23, CDC16, ZW10, BUB3, ANAPC10, MAD2L2, PTTG2, UBE2C |
1802 | GO:1901989 | 0.01 | 2.24 | 16.28 | 24 | 39 | positive regulation of cell cycle phase transition | ANXA1, BIRC5, CCND1, CDC6, CDK4, DDX3X, KCNA5, PBX1, RAD51B, RB1, RDX, SMARCD3, UBE2E2, ZNF16, CDC45, CUL4B, CUL4A, CUL3, TP63, RAB11A, PHOX2B, DLGAP5, UBE2C, PHB2 |
1803 | GO:0002294 | 0.03 | 2.24 | 10.85 | 16 | 26 | CD4-positive, alpha-beta T cell differentiation involved in immune response | ANXA1, BCL3, CD80, CD86, GATA3, HLX, IFNG, PRKCZ, PTGER4, RARA, RELB, TNFSF4, RIPK2, IL18R1, TNFSF18, BATF |
1804 | GO:0044786 | 0.03 | 2.24 | 10.85 | 16 | 26 | cell cycle DNA replication | ATRX, FEN1, PRIM1, PRIM2, RFC1, RFC2, RFC3, RFC4, RFC5, RPA3, SMC1A, CDC45, SMC3, GINS1, STAG2, CHEK2 |
1805 | GO:0060395 | 0.03 | 2.24 | 10.85 | 16 | 26 | SMAD protein signal transduction | BMP1, BMP4, BMP6, BMP8B, GATA4, GDF9, INHA, JUN, SMAD1, SMAD3, CITED1, T, VIM, BMP15, GDF15, RBM14 |
1806 | GO:0090102 | 0.03 | 2.24 | 10.85 | 16 | 26 | cochlea development | ATP2B2, EYA1, FGFR3, GABRB2, HPN, HES1, KCNK2, KCNK3, NTRK3, PAX2, PTK7, RAC1, SIX1, SOX9, IFT88, DCHS1 |
1807 | GO:0009719 | 0.00 | 2.24 | 80.02 | 120 | 207 | response to endogenous stimulus | ABCA1, ACVR2A, ACVR2B, ACVRL1, ADRBK1, AMHR2, APC, XIAP, BMP1, BMP8B, BMPR1A, BMPR2, CAMK4, CAV3, RUNX2, CBL, CCNC, CCNT1, CCNT2, CD9, CD28, CD80, CD86, CD36, CD44, CDK8, CDK9, COL2A1, CSNK1D, CX3CR1, DLX5, E2F4, E2F5, EGR3, ETV2, FCER1G, FOXD1, FNTA, FUT8, KAT2A, GDF9, GPC3, GPC1, HAS1, HAS2, ONECUT1, HPGD, HES1, RBPJ, IL1R1, ILK, ING2, ITGB5, ITPR1, KCND3, LTBP1, LTBP2, SMAD1, SMAD3, SMAD7, OTX2, PCSK6, SERPINE1, PAX2, PPP1CA, PPP2CB, PPP2R1A, RAP1GAP, RBL1, RPS3, RPS6KB2, XCL1, SDCBP, SNAI2, SOX5, SOX11, SP1, SPINT1, SYK, T, CLEC3B, UBE2D1, VAV1, VIL1, WNT2, ZNF8, SHOC2, USP9X, USP9Y, LTBP4, ITGA8, STK16, CHRD, BECN1, IQGAP1, PHOX2B, FIBP, BMP15, ITGB1BP1, NREP, CER1, ZFYVE9, ONECUT2, GDF15, BAG4, CEP57, ADAMTSL2, ZFYVE16, FGFBP1, FSTL3, CXCL13, SPINT2, GIPC1, EHD1, FERMT2, RAB35, STMN2, CORO1A, STRAP, ADAMTS7 |
1808 | GO:0001775 | 0.00 | 2.23 | 74.49 | 110 | 183 | cell activation | ABL2, ADAM10, AHR, ANXA3, APC, RHOH, BAX, BCL3, BMX, ZFP36L2, BST2, CAMK4, CASP8, RUNX2, CBFB, CCND3, CD7, CD8A, TNFSF8, CD151, CDK6, CEBPG, CLC, ACKR2, CR2, CSF2, CX3CR1, CXADR, EDN2, EP300, EPHB1, ERCC1, HHEX, ONECUT1, HPRT1, ICAM1, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, RBPJ, IL2RB, IMPDH1, IMPDH2, INS, ITGA4, ITGAD, ITGB1, JUN, KIT, KRT2, LMO1, CD180, SMAD3, NTRK1, P2RX4, P2RX7, PAX1, PSMB10, PTGER4, PTPRE, RAB27A, RAG2, RELB, RPL22, S100A12, S100A13, SATB1, SELPLG, SLAMF1, SLC11A1, SNCA, SOS2, SOX4, SP3, STK11, STXBP2, TPD52, TSC1, TYROBP, TRPV1, LAT2, WNT1, ZNF3, ZP2, FZD5, EOMES, FZD7, FZD8, FZD9, FOXN1, TPST2, STX11, ADAM9, SNAP23, IL18R1, RNF8, EXO1, IL27RA, SOX13, VPRBP, HDAC4, RNF41, DHRS2, PRG3, BATF, CPLX2, SPINK5, TUSC2 |
1809 | GO:0008652 | 0.00 | 2.23 | 23.79 | 35 | 57 | cellular amino acid biosynthetic process | ABAT, AGXT, ASL, ASNS, ASPA, ASS1, BCAT1, BCAT2, BHMT, CBS, CCBL1, CDO1, CPS1, CTH, DHFR, DHPS, DPYD, GAD1, GAMT, GLS, GLUD1, GLUD2, GLUL, GOT1, GOT2, GPT, OAT, OTC, PAH, PSPH, PYCR1, ALDH18A1, SHMT1, SHMT2, ALDH4A1 |
1810 | GO:0048565 | 0.02 | 2.23 | 12.89 | 19 | 31 | digestive tract development | PRDM1, KLF5, CCNB1, CDKN1A, CDX2, COL3A1, GATA3, GATA6, HRH2, HES1, ITGA6, ITGB4, KIT, NTS, RB1, TRPS1, TYMS, DCHS1, NR1H4 |
1811 | GO:0032989 | 0.04 | 2.23 | 10.07 | 15 | 25 | cellular component morphogenesis | CASQ2, CAV3, CD9, CFL2, AGFG1, KRT19, PRKAR1A, TMF1, TMOD1, TNNT2, CSRP3, CFLAR, TBPL1, FIG4, WDR1 |
1812 | GO:0030902 | 0.00 | 2.23 | 31.30 | 46 | 75 | hindbrain development | AARS, ABAT, ABL2, AGTR2, PHOX2A, RERE, ATP2B2, BCL2, CACNA1A, CDK5, CTNNA2, LPAR1, EGR2, EN1, KAT2A, GRID2, FOXA2, HES1, IGF1, ITGB1, SMAD1, OGDH, OTX1, OTX2, PROX1, PTN, RFX4, SCN5A, SHH, SLC6A4, SSTR2, SSTR3, NR2C2, WNT1, CUL5, USP9X, FZD4, ATRN, ALDH1A2, PHOX2B, CDK5R2, HAP1, NRXN1, SEC24B, ATG7, TBR1 |
1813 | GO:0035295 | 0.00 | 2.23 | 108.72 | 159 | 262 | tube development | ACAT1, ACVR1, ACVRL1, AGTR2, AQP1, AREG, ARG1, ARG2, ATRX, BAX, BBS4, BMPR1A, BMPR2, CASP8, CAT, CAV3, CD44, CDC42, CHI3L1, CP, CTGF, CTSZ, CUX1, CYP1A2, DHCR7, DLG1, EDA, EDN2, EDNRA, EFNB2, EPHA2, EIF4E, EIF4EBP1, EN1, EP300, EPHA4, EPHA7, ESR1, ETV4, ETV5, EYA1, FGF1, FGF3, FGF7, FGF8, FOXD1, KAT2A, GDNF, B4GALT1, GJA5, GPC3, ARHGAP35, HHEX, FOXA2, HOXD11, HSD11B1, TNC, IGF1, IGFBP5, RBPJ, IL13, ILK, ING2, ITGA3, KDR, KRAS, LAMA5, LIPA, LTA4H, TACSTD2, EPCAM, SMAD1, SMAD6, SMAD7, CITED1, NUMA1, OPA1, PBX1, PFN1, PGF, PGR, PPP1CA, PRKACB, MAPK3, PRKX, PSPN, PROX1, PTCH1, PTHLH, PTK7, PTN, RAB3A, RALA, RARA, RYR2, SDC1, SDC4, SRSF6, SFTPD, STIL, SLC8A1, SLC12A2, SOX2, SOX4, SP1, SP3, SPARC, SPINT1, SREBF1, SRF, ST14, T, TSC1, TSC2, TULP3, TWIST1, UBB, KDM6A, VDR, VEGFA, WNT1, WNT2, WNT2B, ZIC2, PAX8, AIMP2, FZD3, IFT88, FZD6, CHRD, NUMB, PROM1, BCL10, CRLF1, ITGB1BP1, CER1, SLIT2, HAND1, HAND2, ADAMTS2, TRAF4, PHF14, ADAMTSL2, SEMA3E, IFT140, ZEB2, BCL2L11, ATP6AP2, COQ7, FSTL3, KLF2, CITED2, SEC24B, DEAF1, PDPN, SPINT2, EDAR, GLMN, PHB2 |
1814 | GO:0065004 | 0.00 | 2.22 | 40.90 | 60 | 98 | protein-DNA complex assembly | AHR, ATRX, CENPA, CENPE, CENPF, CENPI, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, H3F3B, HIST1H1A, PSMC1, PSMC3, PSMC4, PSMC5, RAD51, RAD51B, RAD51D, RB1, RBBP4, SET, SOX9, SOX12, TAF2, TAF7, TSPY1, XRCC2, CHAF1B, HIST1H4I, CDC45, HIST1H2BG, HIST1H2BL, HIST1H2BM, HIST1H2BF, HIST1H2BH, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HAT1, HIST1H3F, HIST1H2BJ, H1FX, TAF1B, IKZF1, OIP5 |
1815 | GO:0048015 | 0.00 | 2.22 | 22.44 | 33 | 54 | phosphatidylinositol-mediated signaling | BAD, CASP9, CD80, CD86, CDKN1A, CHUK, HBEGF, EREG, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, GRB2, NR4A1, KITLG, FOXO4, NTRK1, PDPK1, PIK3C3, PI4KA, PI4KB, PTAFR, RPS6KB2, VAV1, EZR, ZP3, FGF23, OGT, GAB2 |
1816 | GO:0006636 | 0.02 | 2.22 | 12.94 | 19 | 31 | unsaturated fatty acid biosynthetic process | ALOX12, ALOX15B, ANXA1, AVP, CD74, EDN2, FCER1A, GGT7, HPGD, FADS3, LTA4H, MGST2, PTGIS, PTGS1, RNPEP, SYK, AKR1C3, FADS2, PRG3 |
1817 | GO:1903513 | 0.02 | 2.22 | 12.94 | 19 | 31 | endoplasmic reticulum to cytosol transport | ATP1A2, CALM3, CASQ2, CCR5, GSTM2, HRC, PDE4D, PLN, PRKACA, RYR1, RYR2, SEL1L, SLC8A1, UFD1L, GSTO1, AKAP6, TRDN, SEC61B, OS9 |
1818 | GO:2000756 | 0.02 | 2.22 | 12.94 | 19 | 31 | regulation of peptidyl-lysine acetylation | BRCA1, KAT2A, IL1B, ISL1, MAPK3, SET, SNAI2, SNCA, SOX4, TAF7, TWIST1, KAT2B, RPS6KA4, RPS6KA5, ATG5, ATG7, CTCF, RUVBL2, ARID5A |
1819 | GO:0044728 | 0.00 | 2.21 | 20.45 | 30 | 49 | DNA methylation or demethylation | ATRX, BRCA1, DNMT1, TRDMT1, DNMT3A, DNMT3B, GNAS, H3F3B, MGMT, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, FKBP6, HIST1H3F, PICK1, TRIM28, CTCF, BAZ2A |
1820 | GO:0030100 | 0.00 | 2.21 | 34.11 | 50 | 82 | regulation of endocytosis | ABL2, ACTN4, BIN1, ANGPT1, ANXA2, APOC2, ARF1, ARF6, AXL, BICD1, CAV3, CBL, CD14, CD63, AP2S1, DAB2, GPC3, HIP1, ITGB1, NTF3, OPHN1, SERPINE1, PIK3CB, PPT1, PRKD1, PTPN1, RAB4A, RAB5C, RAC1, CCL21, SDCBP, SELE, SFRP4, SNCA, TSC2, TSG101, NR1H2, VEGFA, VTN, PICALM, SYNJ1, PICK1, RUBCN, ZFYVE16, SNX17, DNAJC6, SNAP91, TSPAN1, TNK2, STON1 |
1821 | GO:0045935 | 0.00 | 2.21 | 327.40 | 468 | 788 | positive regulation of nucleobase-containing compound metabolic process | ABCA1, ACVR1, ACVR1B, ACVR2A, ACVRL1, ADCY7, ADCYAP1R1, ADORA2A, ADRB2, AGTR2, AHR, AKT2, ALK, ARF4, PHOX2A, ARNT, ARNTL, ATF3, ATF4, RERE, ATOH1, AVP, AVPR2, BACH1, BCL3, BCL9, BMPR1A, BMPR2, BRCA2, BRDT, ZFP36L2, KLF5, BTK, CALCR, CALM3, CAMK4, CAMK2A, CAT, RUNX2, CBFB, CCNB1, CCNC, CCNE1, CCNH, CCNT1, CCNT2, CD3D, CD80, CD86, TNFSF8, CD38, CDH1, CDK8, CDK9, CDKN2A, CDX1, CDX2, CDX4, CEBPE, CGA, CHD1, CHUK, CLU, COL1A1, ATF2, CREBL2, CRX, CTH, CUX1, DAB2, DCN, DDX3X, DDX5, DLX3, DLX5, DNM2, ARID3A, E2F4, E2F5, EBF1, EDA, S1PR1, EDNRA, EGR2, ELF1, ELF3, ELK1, ELK3, EN1, EP300, EPHA5, ERBB2, ERCC3, ERCC6, ERN1, ESR1, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV4, ETV5, ETV6, EVX1, EZH1, F2R, F2RL1, FGF1, FGF7, FLI1, FSHR, NR5A1, GABPA, GALR1, GATA3, GATA4, GATA6, GCG, KAT2A, NR6A1, GDNF, GHRH, GHRHR, GLP1R, GNAL, GNAS, GPD1, GTF2F1, GUCA1A, GUCA1B, GUCA2A, GUCA2B, H2AFZ, HAS3, HCLS1, HEXB, NRG1, HHEX, HIF1A, HMGN1, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HOXC11, HOXD8, HPN, PRMT2, HES1, HSPA8, ICAM1, IFI16, IFNA2, IGF2, RBPJ, IHH, IL1A, IL1B, IL10, FOXK2, ILK, ING2, INSIG1, INSL3, IRAK1, ITGA6, IRAK2, IRF1, IRF2, IRF5, ISL1, JUNB, JUND, JUP, KIT, KRAS, ABLIM1, LMO1, LTF, LUM, EPCAM, SMAD1, SMAD3, SMAD7, MEIS1, MEN1, MEOX2, CIITA, AFF1, FOXO4, CITED1, PPP1R12A, NRF1, NRL, YBX1, NTF3, NTRK1, NTRK2, DDR2, SIX6, OTX1, OTX2, P2RX7, P2RY1, P2RY11, SERPINE1, PARK2, PAX1, PAX2, PAX9, PBX1, PCK1, PER1, PF4, PGR, PHB, PHF2, PRRX1, PPM1A, PPP3R1, PRKAA1, PRKCA, PRKCB, PRKCI, PRKD1, PRKCZ, EIF2AK2, PROX1, RELN, PSMA6, PSMC1, PSMC3, PSMC4, PSMC5, PTCH1, PTGER4, PTHLH, PTPN1, RAF1, RAN, RARA, RARB, RB1, ARID4A, RBL1, RCVRN, RELB, REST, RFX3, RFX4, RFXAP, RNF6, RPS6KA1, RPS6KA3, RPS27A, RREB1, RXRA, RXRG, S100A8, S100A9, S100A12, SAFB, SALL1, ATXN7, TRA2B, SHH, SIX1, SIX3, SLC9A1, SLC11A1, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCC2, SMARCD3, SNAI1, SNRNP70, SOX1, SOX2, SOX4, SOX5, SOX9, SOX10, SOX11, SOX12, SP1, SP3, SP100, SREBF1, SRF, SRY, SSRP1, STAT3, STAT4, STAT5B, SUPT4H1, SUPV3L1, T, TAF2, TAF7, TAL1, TBL1X, TBP, HNF1A, NR2F2, NR2E1, TNFRSF1A, TNNI2, TP73, NR2C2, TRAF1, TRAF2, TRPS1, TSC2, TWIST1, UBB, UBE2V1, UBE3A, UBTF, NR1H2, USF1, USF2, VDR, VEGFA, VIP, VIPR2, WFS1, WNT1, WNT2, WNT11, YWHAH, ZFP36, ZIC1, ZIC2, ZNF711, CNBP, ZSCAN21, TRIM25, ZNF148, ZBTB17, ZP3, ZXDA, LRP8, PAX8, FZD5, BRPF1, MAFK, ARHGEF5, CSRP3, FOSL1, FGF23, NRIP1, PICALM, EOMES, FZD4, FZD7, FZD8, UTF1, OGT, ITGA8, IKBKG, CAMK1, STK16, TNFSF11, KLF7, RFXANK, TP63, TRADD, EDF1, RIPK1, RIPK2, TRIM24, CFLAR, HDAC3, KAT2B, NR1I2, BUD31, BCL10, PHOX2B, FUBP3, RPS6KA4, TNFSF18, BAZ1B, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, VAPB, CCPG1, RPS6KA5, ITGB1BP1, HMGN3, TRIP4, CNOT8, HAND1, EIF2AK3, FHL5, HAND2, ONECUT2, GTPBP1, NR1D1, CLOCK, CREB5, GUCA1C, ZNF516, HDAC4, BCLAF1, SERTAD2, ZEB2, RNF10, NR1I3, NR1H4, NR1D2, NR2E3, YAF2, CEBPZ, ALYREF, RNF41, CALCRL, COQ7, SF3B4, RAMP2, FSTL3, STAG1, TNIP1, IKZF1, TRIM22, KLF2, CITED2, RAPGEF3, RBM14, MAD2L2, SLC30A9, TRIM38, CAP2, CAP1, CREB3, DEAF1, BATF, USP16, ERLIN1, RBCK1, ARID3B, TRIM16, DMRT2, KLF1, CTCF, TBR1, STAG2, SIX2, RAI1, RUVBL2, ARID5A, MALT1, PRDX3, SLC38A3, PIM2, WWP2, ERLIN2, PSIP1, SUPT16H, CHEK2, KLF12, PHB2 |
1822 | GO:0006919 | 0.01 | 2.21 | 15.00 | 22 | 36 | activation of cysteine-type endopeptidase activity involved in apoptotic process | BAD, BID, BOK, CASP9, CCK, CDKN2A, COL4A3, F2R, F3, HIP1, SLC11A2, S100A8, S100A9, SNCA, CRADD, AIFM1, EIF2AK3, TNFSF15, CASP8AP2, PDCD6, BCL2L10, BCL2L11 |
1823 | GO:0051094 | 0.00 | 2.21 | 37.85 | 56 | 94 | positive regulation of developmental process | ANGPT2, ANXA3, AQP1, CCND1, BMP1, BNIP3, BRCA1, C5, CBLB, CD28, CD40, CDKN2A, CHI3L1, CCR3, DCN, ECM1, EPHA1, F3, FGF7, FLT1, GPM6B, HMGCR, HMGA1, HPN, HSPB1, IL1A, IDO1, ISL1, ITGA5, P2RX7, SERPINE1, ENPP2, PGF, PRKAA1, PRKCB, MAPK8, PTGIS, RRAS, CCL24, SRSF6, SLC8A1, NR2E1, TNFAIP3, UNG, VEGFB, WHSC1, ZIC2, FOXN1, TRADD, TNFSF13, TNFSF12, USP2, HAND2, PDCD6, TNFSF13B, SEPT9 |
1824 | GO:0034440 | 0.00 | 2.20 | 22.54 | 33 | 54 | lipid oxidation | ACAA1, ACADL, ACADM, ACADS, ACADSB, ACADVL, ACOX1, AKT2, ABCD1, ALOX12, CNR1, CPT1B, CPT2, DECR1, ECH1, EHHADH, ETFA, ETFDH, HADHA, HSD17B4, IVD, PCCA, PDK4, PRKAA1, ABCD3, SCP2, TWIST1, ACOX2, ACOX3, ACOT8, ECI2, SLC25A17, SLC27A2 |
1825 | GO:0060491 | 0.00 | 2.20 | 32.13 | 47 | 77 | regulation of cell projection assembly | APC, AQP1, ARF6, BBS4, KLF5, CAPZB, CDC42, CYLD, DNM2, DPYSL3, EPHA2, F2RL1, GAP43, GPM6A, HRG, ICAM1, KIT, TACSTD2, ODF2, P2RX7, ATP8B1, PFN1, PFN2, PRKCQ, RAC1, RAC2, RALA, RAP1GAP, RDX, CCL21, SRF, CLRN1, WNT1, IFT88, HAP1, SLIT2, NRXN1, ATG5, IFT140, HDAC4, ARPC2, WASF2, CDC42EP2, CDC42EP3, SEPT9, CDC42EP1, TWF2 |
1826 | GO:0051402 | 0.05 | 2.20 | 9.53 | 14 | 23 | neuron apoptotic process | BID, BNIP3, BOK, ATN1, ESR1, GAPDH, GATA3, GPX1, GRID2, RB1, SIAH1, TP63, AATK, SIGMAR1 |
1827 | GO:0021872 | 0.01 | 2.20 | 15.02 | 22 | 36 | forebrain generation of neurons | DCX, FGF8, GNAQ, HES1, OGDH, PROX1, RAC1, RAC3, SALL1, SMARCC2, SOX1, SOX2, CNTN2, NR2E1, UBB, NUMB, NUMBL, SLIT2, RAPGEF2, SEMA3A, ATG7, TBR1 |
1828 | GO:0042633 | 0.00 | 2.20 | 24.62 | 36 | 59 | hair cycle | AARS, ACVR1B, APC, ARNTL, BCL2, CDC42, CDH3, CTSV, DBI, DNASE1L2, EDA, FGF7, GNAS, IGFBP5, RBPJ, KRT14, KRT16, KRT33B, KRT83, KRT84, LAMA5, PER1, SHH, SNAI1, SNRPE, SOX9, FZD3, FZD6, FOXN1, TP63, PTCH2, TRADD, CLOCK, EDAR, SPINK5, SOX21 |
1829 | GO:0050729 | 0.01 | 2.20 | 17.08 | 25 | 41 | positive regulation of inflammatory response | CD6, CTSS, EDNRA, IL18, IDO1, ITGA2, SERPINE1, PRKCA, PTGER4, RPS19, S100A8, S100A9, S100A12, CCL24, XCL1, CX3CL1, STAT5B, XCL2, TNFRSF1A, TNFSF4, VAMP8, TNFSF18, IL1RL1, CLOCK, TNIP1 |
1830 | GO:0002376 | 0.02 | 2.19 | 13.26 | 20 | 35 | immune system process | ADSS, AHR, CCND3, CD5L, CD151, EPHB1, HP, HPRT1, IMPDH1, IMPDH2, INPPL1, LMO1, LRMP, ORM2, PTPRE, TRPV1, ZNF3, ADAM9, RUBCN, SIVA1 |
1831 | GO:0043488 | 0.00 | 2.19 | 38.39 | 56 | 92 | regulation of mRNA stability | ZFP36L2, CIRBP, DHX9, EIF4G1, ELAVL1, GDNF, HSPA8, HSPB1, TNPO1, YBX1, EXOSC9, PRKCA, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SET, SLC11A1, UBB, SCGB1A1, VIP, YWHAZ, ZFP36, NUP214, ANP32A, KHSRP, TNFSF13, QKI, PSMF1, PUM1, PSMD6, PSME3, EXOSC8 |
1832 | GO:0005976 | 0.05 | 2.19 | 9.57 | 14 | 23 | polysaccharide metabolic process | EXT1, EXT2, GYS2, HAS1, HAS3, PPP1R1A, PPP1R2, PPP1R3C, RPS27A, UBB, UGP2, EPM2A, NR1D1, B3GNT3 |
1833 | GO:0015696 | 0.05 | 2.19 | 9.57 | 14 | 23 | ammonium transport | ADA, CACNA1A, EDNRA, FCER1A, FCER1G, GPM6B, SEC14L1, SLC6A4, SYK, TACR2, TAF7, VAMP8, SNAP23, HRH3 |
1834 | GO:0045814 | 0.00 | 2.18 | 30.88 | 45 | 74 | negative regulation of gene expression, epigenetic | CCNH, DNMT1, DNMT3A, DNMT3B, ERCC3, HIST1H2AE, HIST1H2AD, H2AFZ, H3F3B, HMGA1, JARID2, PHF2, RBBP4, SUV39H1, TBP, TTF1, UBTF, HIST1H4I, CDC45, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HAT1, EED, SAP30, HIST1H3F, HIST1H2AG, TAF1C, TAF1B, TAF1A, SAP18, BAZ2A |
1835 | GO:0051351 | 0.00 | 2.18 | 30.88 | 45 | 74 | positive regulation of ligase activity | BMI1, CCNB1, CDC20, CDC27, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SKP1, UBB, UBE2D1, UBE2L3, XRCC4, CUL1, CDC14B, CDC23, CDC16, PSMF1, PSMD6, PSME3, ANAPC10, UBE2C |
1836 | GO:0055001 | 0.00 | 2.18 | 30.88 | 45 | 74 | muscle cell development | ACTG1, AGTR2, BCL2, BMP4, CACNA1S, CACNB4, CASQ2, CAV2, CAV3, CCNB1, CFL2, CXADR, FLNC, GATA4, GPX1, HES1, IGF1, ITGB1, KRT19, PRKAR1A, PROX1, RYR1, SDC1, SGCB, SGCD, SLC8A1, SRF, TMOD1, TNNT2, COL14A1, VEGFA, XK, CSRP3, SORBS2, CFLAR, CTDP1, AKAP6, ATG5, HDAC4, WDR1, RAMP2, SPEG, ATG7, PDLIM5, BVES |
1837 | GO:0048839 | 0.03 | 2.18 | 11.64 | 17 | 28 | inner ear development | BMP4, C1QB, CUX1, DFNA5, IGF1, RBPJ, KCNQ1, ATP8B1, SDC4, SHH, SPARC, USH2A, LIN7A, PHOX2B, ATG5, CXCL14, GJB6 |
1838 | GO:0001558 | 0.01 | 2.18 | 17.78 | 26 | 43 | regulation of cell growth | FXYD2, CISH, CTGF, IGFBP2, IGFBP3, IGFBP5, IGFBP6, PRKCQ, TSG101, COL14A1, BAP1, LTBP4, BLZF1, URI1, WISP3, WISP1, TAOK2, BCAR1, SGK2, RASGRP2, MAD2L2, CREB3, FBLN5, NRG3, OGFR, ESM1 |
1839 | GO:0072593 | 0.01 | 2.18 | 15.73 | 23 | 38 | reactive oxygen species metabolic process | ALOX12, AOX1, APOA4, CAT, CTGF, CYP1A2, FANCC, GPX1, GPX3, HBA1, HBA2, P2RX7, PDK4, SFTPD, SOD2, PRDX2, VAV1, PXDN, EPX, PRDX6, PRG3, PRDX4, PRDX3 |
1840 | GO:0045861 | 0.00 | 2.18 | 95.99 | 139 | 230 | negative regulation of proteolysis | A2M, SERPINA3, AHSG, AKT2, AMBP, APC, BIRC3, XIAP, BIRC5, APLP2, AQP1, SERPINC1, ATM, AVP, BST2, BUB1, BUB1B, SERPING1, C3, C5, CASP8, SERPINH1, CCNB1, CD44, CD59, CDC20, CDC27, CDK5, CDKN2A, CDKN2D, CENPF, COL4A3, COL6A3, CR1, CRYAB, CSNK2A1, CSNK2A2, CST1, CST6, CD55, DDX3X, DHCR24, DPEP1, DUSP1, ECM1, SERPINB1, IFI6, GAS1, GAS6, GPC3, SFN, GPX1, SERPIND1, HGF, HRG, DNAJB2, HSP90AB1, IDE, IFI16, IL10, INS, ITIH1, ITIH2, ITIH3, ITIH4, KNG1, MAD2L1, CD46, OPHN1, PEBP1, SERPINE1, PAX2, SERPINA5, SERPINF1, PI3, SERPINB6, SERPINB8, SERPINB9, SERPINB10, SERPINI1, SERPINB13, PRKCG, PROS1, PTPN3, PZP, RAF1, RAG1, RPS6KA1, RPS6KA3, SERPINB3, SERPINB4, SDCBP, SHH, SIAH2, SLPI, SMARCC1, SNCA, SORL1, SPINK1, SPINT1, SERPINA7, TRAF2, UBE2D1, NR1H2, VEGFA, VIL1, VTN, WNT1, ZNF207, PICALM, RECK, CDC23, SERPINB7, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR, CDC16, USP14, ZW10, BUB3, KLF4, PSMF1, TMEM59, BAG5, HDAC6, ANAPC10, MAD2L2, SPINT2, PTTG2, GIPC1, SPINT3, USP19, PRDX3, SPINK5, UBE2C |
1841 | GO:0002684 | 0.00 | 2.17 | 42.95 | 63 | 106 | positive regulation of immune system process | ACVR1B, ACVR2A, ADK, ARNT, ATP6AP1, AXL, BAD, PRDM1, CA2, CD2, CD5, CD6, CD37, CDKN1A, CHRNB2, DHPS, DPP4, GPR183, EFNB2, EGR3, ETS1, FLOT2, FLT3LG, GNAS, HCLS1, HIF1A, PRMT1, HES1, IGF1, IGF2, IGFBP2, IHH, IL2RA, IL18, ITGAL, ITPKB, ABCB1, PRKCA, RAG1, RB1, SHH, SPN, SPTA1, STXBP2, TAC1, TAL1, KLF10, TNFRSF4, ZNF16, OGT, AP3B1, TNFSF11, TNFSF9, IL1RL2, CD84, VNN1, AP3D1, IL1RL1, EBI3, TRIB1, IKZF1, HHLA2, CORO1A |
1842 | GO:0042445 | 0.00 | 2.17 | 41.29 | 60 | 99 | hormone metabolic process | ALDH1A1, ALDH1A3, ALDH9A1, ANPEP, ARNT, BMP6, CACNA1A, SCARB1, CGA, AKR1C4, COMT, CPA3, CRYM, CTSG, CTSZ, CYP3A4, CYP11B1, DIO1, DIO2, ENPEP, ESR1, FDXR, NR5A1, GATA3, GHRHR, FFAR3, HIF1A, HPN, HSD17B3, HSD17B4, IL1B, PCSK6, PCSK1, PCSK5, KLK6, RBP1, REST, SAFB, SCP2, SHH, SLC5A5, SRD5A1, STAR, STAT5B, SULT1E1, SULT1A1, TSHB, UGT2B7, PAX8, DDO, AKR1C3, DGAT1, ALDH1A2, SGPL1, PCSK7, DHRS3, ATP6AP2, DHRS9, DHRS2, CORIN |
1843 | GO:0043266 | 0.03 | 2.17 | 11.67 | 17 | 28 | regulation of potassium ion transport | ADORA1, ADRB2, ATP1B3, DLG1, DNM2, DPP6, EDN3, KCNJ2, KCNS1, KCNS2, ABCC8, KCNAB2, AKAP7, AKAP6, AKAP9, RAPGEF3, WWP2 |
1844 | GO:0006611 | 0.03 | 2.17 | 11.67 | 17 | 28 | protein export from nucleus | ADAR, BARD1, CDK5, CDKN2A, EGR2, EIF5A, HSPA9, NUP88, PTPN14, RAN, SOX4, SP100, STYX, NUP214, NUTF2, AHCYL1, NUPL2 |
1845 | GO:1902806 | 0.00 | 2.17 | 41.32 | 60 | 99 | regulation of cell cycle G1/S phase transition | ANXA1, ATM, CCND1, BCL2, BID, CDC6, CDKN1A, DDX3X, PRMT2, KCNA5, MEN1, PIM1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN6, RB1, RDX, RPS27A, SMARCA4, SOX4, TP73, UBB, UBE2E2, CDC45, CUL4B, CUL4A, TP63, CRADD, PSMF1, PSMD6, CTDSP2, PSME3, CTDSPL, PDPN, ECD, PHB2 |
1846 | GO:0006754 | 0.03 | 2.16 | 11.69 | 17 | 28 | ATP biosynthetic process | ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, LDHC, STAT3, SURF1, ATP5J2, SLC25A13, ATP5H, ATP5L |
1847 | GO:0022029 | 0.03 | 2.16 | 11.69 | 17 | 28 | telencephalon cell migration | CDK5, CX3CR1, DCX, NRG1, OGDH, RELN, RAC1, SRF, CNTN2, NR2E1, TNR, LRP8, CUL5, CDK5R2, SLIT2, SEMA3A, NRG3 |
1848 | GO:0043550 | 0.03 | 2.16 | 11.69 | 17 | 28 | regulation of lipid kinase activity | CDC42, EEF1A2, EPHA8, FGFR3, FGR, FLT1, FLT3, KIT, RAC1, RB1, RBL1, RBL2, CCL21, PIK3R3, KLF4, RUBCN, VAV3 |
1849 | GO:0050881 | 0.03 | 2.16 | 11.69 | 17 | 28 | musculoskeletal movement | ADRB2, ATP2A1, CACNA1A, CAV3, CHUK, EEF2, GAA, GSTM2, ITPR1, KCNJ2, SLC8A3, TNNC2, TNNC1, TNNI2, TNNI3, TNNT1, GSTO1 |
1850 | GO:0001649 | 0.01 | 2.16 | 17.85 | 26 | 43 | osteoblast differentiation | ADAR, CAT, CBFB, CLTC, COL1A1, VCAN, CYP24A1, DHX9, EPHA2, FGF9, HSD17B4, TNC, IGFBP3, IHH, JUNB, PCP4, PENK, PHB, RPS11, SNAI1, WNT11, SEMA7A, DDX21, NR1I3, ALYREF, GPNMB |
1851 | GO:0019722 | 0.01 | 2.16 | 15.82 | 23 | 38 | calcium-mediated signaling | ATP1A2, BTK, CASQ2, CCR5, CMKLR1, RCAN1, EDN2, HRC, ITPR1, P2RY11, PDE4D, PDPK1, PLN, PPP3R1, SELE, SLC8A1, LAT2, RGN, EIF2AK3, HDAC4, RCAN2, RCAN3, PTGDR2 |
1852 | GO:0002292 | 0.02 | 2.15 | 13.77 | 20 | 33 | T cell differentiation involved in immune response | ANXA1, BCL3, CD80, CD86, FCER1G, GATA3, HLX, IFNG, CD46, PRKCZ, PTGER4, RARA, RELB, TSC1, TNFSF4, EOMES, RIPK2, IL18R1, TNFSF18, BATF |
1853 | GO:0048278 | 0.02 | 2.15 | 13.77 | 20 | 33 | vesicle docking | CAV2, CFTR, RAB8A, RAB13, SNAP25, STXBP1, STXBP2, STXBP3, SYT1, USO1, STX16, STX11, STX10, SNPH, STX6, RABEPK, UNC13B, EXOC5, CPLX2, BVES |
1854 | GO:0051153 | 0.02 | 2.15 | 13.77 | 20 | 33 | regulation of striated muscle cell differentiation | BCL2, BMP4, CAV3, CD53, EFNB2, FLT3LG, NRG1, RBPJ, YBX1, PROX1, SHH, COL14A1, TNFSF14, CFLAR, HDAC3, CTDP1, AKAP6, GDF15, HDAC4, EHD1 |
1855 | GO:0072384 | 0.02 | 2.15 | 13.77 | 20 | 33 | organelle transport along microtubule | BICD1, CDC42, AP3S1, DYNC1I1, BLOC1S1, HIF1A, OPA1, PEX14, PRKCZ, RAB1A, RAB6A, UBB, UXT, AP3B1, AP3D1, HAP1, KIF3B, AP3S2, AP3M2, KIF3A |
1856 | GO:0032386 | 0.02 | 2.15 | 14.40 | 21 | 35 | regulation of intracellular transport | ABCA2, BST2, CRYAB, GDI1, KCNE1, PFN2, SEPT5, PTPN1, RAB3A, RAP1A, STXBP1, STXBP2, SYN1, TNNC1, TNNT2, OGT, CD84, RAB11B, GOSR1, RIMS3, BVES |
1857 | GO:0061041 | 0.01 | 2.15 | 19.97 | 29 | 48 | regulation of wound healing | ABAT, ADRB2, ALOX12, ANXA2, ANXA5, APCS, SERPINC1, SERPING1, F2RL1, FAP, FCER1G, FGA, FGG, GP1BA, HMGCR, FOXA2, KLKB1, KNG1, KRT1, SMAD3, PRKCA, PRKCQ, PRKG1, PROC, PROS1, SRSF6, SYK, TNFAIP3, VIL1 |
1858 | GO:0050777 | 0.01 | 2.15 | 17.92 | 26 | 43 | negative regulation of immune response | AMBP, ANGPT1, ANXA1, APOA1, BST2, CD59, COL3A1, CD55, GPX1, HLX, IFNA2, IL2RA, IL10, CD46, PSMB4, PTPN6, XCL1, SPN, TNFSF4, CD84, PGLYRP1, TNFSF18, IL1RL1, IL27RA, OLFM4, SPINK5 |
1859 | GO:0046395 | 0.00 | 2.15 | 34.48 | 50 | 83 | carboxylic acid catabolic process | ACAT1, ALDH9A1, AMT, ARG1, ASL, ASPA, ALDH7A1, AUH, BCAT1, BCAT2, BCKDHA, CBS, CCBL1, CDO1, CRYM, SLC25A10, CTH, DAO, DLD, GAD1, GAD2, GLS, GLUD1, GLUD2, GLUL, GOT1, GPT, GSTZ1, HSD17B10, HAL, HMGCL, HPD, IDO1, ALDH6A1, OAT, OGDH, OTC, PAH, QDPR, SHMT1, SUOX, TAT, TST, BBOX1, DDO, KYNU, AASS, BCKDK, ALDH1L1, SDS |
1860 | GO:0001895 | 0.01 | 2.15 | 15.86 | 23 | 38 | retina homeostasis | ABCA4, ACTB, ACTG1, ALB, AZGP1, BBS1, BBS2, BBS4, CDH3, CLCN3, ERCC6, HSPB1, KRT1, LTF, PIGR, SOD1, TULP1, USH2A, CLRN1, PROM1, IQCB1, CROCC, CIB2 |
1861 | GO:0030279 | 0.01 | 2.15 | 15.86 | 23 | 38 | negative regulation of ossification | ADRB2, AHSG, AREG, BCL2, CDK6, CCR1, ECM1, HIF1A, IGFBP5, RBPJ, SMAD3, MEN1, CITED1, P2RY2, SRGN, PTCH1, SOX2, SOX9, TWIST1, FGF23, CHRD, HAND2, HDAC4 |
1862 | GO:0060021 | 0.01 | 2.15 | 15.86 | 23 | 38 | palate development | ACVR2B, BMPR1A, COL2A1, DLG1, DLX5, DLX6, EPHB2, EPHB3, INSIG1, MEOX2, PRRX1, SHH, SNAI2, SNAI1, SOX11, TWIST1, SUMO1, WNT11, IFT88, SGPL1, DHRS3, HAND2, VAX1 |
1863 | GO:0043900 | 0.00 | 2.15 | 49.65 | 72 | 120 | regulation of multi-organism process | ACVR1B, AP2A1, AP2B1, AP1G1, ANXA5, BIRC3, ARF1, BMP6, CA7, CD4, CD37, AP2M1, AP1S1, AP2S1, CNR1, COX8A, CPA3, CLDN7, CYBA, CD55, EDNRB, EIF2S1, FCER2, FCGR3B, FGF7, FYN, SLC37A4, B4GALT1, GLRA1, HCK, KCNQ1, CD180, MDH1, NTHL1, OXT, P2RX7, P2RY1, P2RY2, PDK4, PGC, SERPINB10, PRKCA, KLK7, PTAFR, RAC1, SCN1A, SNRPD1, SPINK1, SPN, STAT2, VIP, ZNF189, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, AP1S2, AP1M1, HIST1H3F, CHST3, NUP93, PUM1, PHYHIP, IST1, ELMO1, FGFBP1, AP1M2, CREB3, CSPG5, TRAF3IP2 |
1864 | GO:0005996 | 0.00 | 2.15 | 44.88 | 65 | 108 | monosaccharide metabolic process | ADRA1B, AKT2, BAD, BRS3, CACNA1A, CALM3, CYB5R3, FUT6, FUT8, SLC37A4, GAA, GALE, GALK1, GALK2, GCGR, B4GALT1, GLB1, GPLD1, GYS2, HK2, FOXA2, ONECUT1, IGF1, IGF2, IGFBP3, IGFBP5, INPPL1, KCNJ11, KHK, LDHA, MAN2B1, OAS1, PARK2, PDK4, ENPP1, PFKFB2, PFKFB4, PHKA2, PHKG1, PPP1CA, PPP1R3C, PPP2R5D, PRKAA1, PRKCE, PYGL, PYGM, RPE, RPS27A, SLC2A3, UBB, UGDH, UGP2, UGT2B4, UGT2B7, UGT8, USF1, EPM2A, DYRK2, EPM2AIP1, XYLB, SLC23A2, SORBS1, FUT9, UGT2A1, DUSP12 |
1865 | GO:0044248 | 0.00 | 2.14 | 65.92 | 96 | 163 | cellular catabolic process | ABAT, ABL2, ACAT1, ACHE, ACTL6A, ADH5, ALDH9A1, AMT, ANPEP, ARG1, ASL, ASPA, ALDH7A1, AUH, BCAT1, BCAT2, BCKDHA, BHMT, BNIP2, BPGM, CALM3, CAPN1, CDK5, TPP1, CRYM, CYP1A2, CYP3A4, CYP3A5, CYP24A1, CYP27B1, DAO, ACE, DLD, DPEP1, EEF1A2, CTTN, ENPEP, ESD, G6PC, GAA, GAD1, GAD2, KAT2A, GFAP, GK, GK2, GLS, GLUD1, GLUD2, GLUL, GOT1, GOT2, GPD2, GPT, HSD17B10, HMGCL, IFI16, LTA4H, ALDH6A1, OAT, OGDH, OTC, OXCT1, PGAM2, PGM1, PHKA2, PHKG1, PYGL, PYGM, RNPEP, SHMT1, SORD, SREBF1, SULT2A1, U2AF1, XPNPEP1, ZBTB17, FZD5, FGF23, IFT88, BBOX1, DDO, ALDH4A1, NR1I2, MGAM, STBD1, RAB33A, GPRASP1, RB1CC1, XYLB, AASS, BCKDK, AKR1A1, SDS, ADAMTS13, TREH |
1866 | GO:0030071 | 0.01 | 2.14 | 17.95 | 26 | 43 | regulation of mitotic metaphase/anaphase transition | APC, ATM, BUB1, BUB1B, CCNB1, CDC6, CDC20, CDC27, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, MAD2L1, RB1, UBE2D1, ZNF207, CUL3, CDC23, CDC16, ZW10, BUB3, DLGAP5, ANAPC10, MAD2L2, UBE2C |
1867 | GO:2000177 | 0.01 | 2.14 | 17.95 | 26 | 43 | regulation of neural precursor cell proliferation | CTNNA1, CX3CR1, EMX1, RAPGEF1, HIF1A, IGF1, IL1B, ILK, PROX1, PTPRZ1, RSU1, SALL1, CX3CL1, SHH, SIX3, SLC6A4, SMARCD3, SOX2, SOX10, SPINT1, NR2E1, VEGFA, VEGFC, FZD3, SPINT2, VAX1 |
1868 | GO:0002064 | 0.00 | 2.14 | 40.76 | 59 | 98 | epithelial cell development | ACTA2, ARNTL, ATP2B2, BAD, PRDM1, BMP4, BMP6, KLF5, CDC42, CDK6, CLDN3, DNASE1L2, E2F4, S1PR3, F2RL1, GATA3, GDNF, B4GALT1, SFN, GPX1, RAPGEF1, ONECUT1, HRH2, IHH, IL1B, CITED1, PAX2, PDE4D, PDPK1, PROC, RAC1, RAP1A, RARA, RARB, RDX, RHEB, SALL1, SOD1, ST14, STC1, TNFRSF1A, CLRN1, EZR, VEZF1, PAX8, IFT88, FZD7, TP63, IQGAP1, BMP15, S1PR2, SLC9A3R1, ONECUT2, CLOCK, RAPGEF2, RAPGEF3, SEC24B, SPINT2, SIX2 |
1869 | GO:0032940 | 0.00 | 2.14 | 68.83 | 100 | 169 | secretion by cell | A2M, ABCA1, ACTN4, ACTN1, ACVR2B, ALB, ANXA3, AQP1, ARL4D, AXL, SERPING1, CACNA1B, CALM3, CALU, CAMK2G, CD9, CD36, CD63, CHI3L1, CLU, CCR1, CTGF, FGF7, FLNA, GAD1, GAD2, GCGR, HCK, HGF, HRG, HSPA8, IGF2, RBPJ, IL1RN, KIT, KNG1, LAMP2, LTBP2, RAB8A, PCSK6, SERPINE1, PCSK5, PF4, PFN1, PIK3C2A, PIK3CG, PPT1, PROS1, PTPRN, PTPRN2, RAB1A, RAB13, RAF1, S100A12, S100A13, SELP, SLC6A11, SLC6A12, SLC6A13, SLC22A2, SOD1, SPARC, HNF1A, TNFAIP2, TUBA4A, TYRO3, VCL, VEGFA, VEGFB, VIP, LAT2, SCG2, SYN3, FZD4, LTBP4, STX11, RAB11A, SNAP23, LIN7A, SYNJ1, DGKI, RAB11B, SNAP29, NRXN3, NRXN2, EIF2AK3, SNPH, SCRN1, WDR1, RABEPK, ABCC4, CAP1, ARFGEF2, ARFGEF1, EXOC5, TNFSF13B, TRAF3IP2, TMED10, RAB31, CORO1A |
1870 | GO:0009792 | 0.00 | 2.14 | 126.79 | 182 | 304 | embryo development ending in birth or egg hatching | ACVR1, ACVR1B, ACVR2A, ACVRL1, ADA, ADAM10, ADAR, ADD1, ALX3, ANGPT1, ARNT, ASCL2, ATM, BBS4, BCL2L1, PRDM1, BMP4, BMPR1A, BRCA1, BRCA2, BTF3, BYSL, C5, CASP8, RUNX2, CCNB1, CDX1, CDX2, CDX4, COL1A1, COL2A1, COL11A1, CSF2, DAD1, DDX5, DLG1, DMBT1, DSC3, EDNRA, EPHA2, ELF3, EMX1, EN1, EP300, ETV2, EVX1, EXT1, EYA1, FGF8, FGF9, FUT8, GABPA, GATA3, GATA4, GATA6, KAT2A, GJB5, GNAS, GRB2, GRN, ARHGAP35, HHEX, HIF1A, FOXA2, HOXC11, HOXD3, HOXD4, HOXD11, HES1, IGF1, RBPJ, IHH, IL10, INSL3, ISL1, ITGA4, ITGB1, KRT19, LLGL2, SMAD3, MEOX2, CITED1, CNOT2, YBX1, OCRL, OPA1, OTX2, P2RY2, PAX1, PAX2, PBX1, PCDH8, PCSK5, PFN1, PRRX1, PRKACB, PROX1, PSMC3, PSMC4, PTCH1, PTK7, PTPRR, RAD51B, RALA, RARA, RBBP6, RBBP8, RCN1, RXRA, SALL1, SDC4, SRSF1, SHH, STIL, SIX1, SLC8A1, SNAI1, SOX4, SOX5, SOX10, SOX11, SP2, SPINT1, SRF, ST14, T, NR2F2, TSC1, TSC2, TULP3, TWIST1, KDM6A, VEGFA, WNT1, WNT2, WNT11, XRCC2, ZIC2, SLC30A1, ZP3, FZD5, FZD3, FOSL1, USP9X, EOMES, FZD6, CUL4A, CUL3, COPS3, DCHS1, CHRD, DLK1, ALDH1A2, EIF2S2, BCL10, SOCS3, LATS1, CCNB2, SLIT2, HAND1, HAND2, APBA3, IFT140, GINS1, ZEB2, SETDB1, ABI1, BCL2L11, COL4A3BP, TRIM28, ATP6AP2, COQ7, IRX5, SPEG, KLF2, SEC24B, DEAF1, SLC34A2, SPINT2, DMRT2, SIX2, GLMN |
1871 | GO:0045834 | 0.00 | 2.14 | 24.18 | 35 | 58 | positive regulation of lipid metabolic process | ANXA1, AVP, BMP6, SCARB1, CDC42, CREBL2, EEF1A2, EPHA8, ACSL3, FGF1, FGFR3, FGR, FLT1, FLT3, GHSR, GPLD1, HTR2C, IFNG, INS, KIT, PRKAA1, RAC1, SCP2, CCL21, SMPD2, SREBF1, TNFRSF1A, NR1H2, ZP3, NSMAF, RGN, NR1D1, ABCG1, VAV3, SORBS1 |
1872 | GO:0009156 | 0.00 | 2.14 | 22.12 | 32 | 53 | ribonucleoside monophosphate biosynthetic process | ADA, ADK, ADSL, ADSS, AK2, AK4, AMPD1, AMPD2, APRT, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, DHODH, HPRT1, IMPDH1, IMPDH2, LDHC, PRPS2, STAT3, SURF1, UPP1, ATP5J2, SLC25A13, ATP5H, ATP5L |
1873 | GO:0048863 | 0.00 | 2.14 | 63.80 | 92 | 153 | stem cell differentiation | A2M, ACVR1, BCHE, BCL2, BMP4, BMPR1A, ZFP36L2, RUNX2, COL1A1, DAB2, EDN3, EDNRA, EDNRB, EFNA1, ELAVL1, EPHA3, ERG, ETV4, FGF8, FLNA, GATA4, GATA6, GDNF, GPM6A, HAS2, HGF, NRG1, HHEX, HIF1A, FOXA2, HOXD4, HPN, HES1, RBPJ, ISL1, JARID2, KIT, LAMA5, TACSTD2, EPCAM, SMAD3, SMAD7, KITLG, FOXO4, CNOT2, NRTN, NTF4, PAX2, MAPK3, PSMD11, REST, S100A4, SERPINB3, SDCBP, SEMA3F, SHH, SIX3, SNAI2, SNAI1, SOX2, SOX5, SOX9, SOX10, SOX11, T, TWIST1, WNT2, WNT11, PAX8, SEMA3B, EOMES, SEMA7A, TP63, ADAM15, ALDH1A2, PHOX2B, HAND2, PUM1, SEMA3E, CUL7, ZEB2, TRIM28, SEMA3A, OLFM1, MAD2L2, SEMA6C, SEMA6B, SEMA4F, SEMA4B, SIX2, SOX21, STRAP |
1874 | GO:0043436 | 0.00 | 2.14 | 27.35 | 40 | 68 | oxoacid metabolic process | ANGPT1, BNIP2, EXT1, EXT2, EXTL1, EXTL2, EXTL3, GPC4, GPC5, GALNS, B4GALT1, GPC3, GLB1, GPC1, HEXA, HEXB, IDS, LUM, CHST6, OMD, OGN, SDC1, SDC2, SDC4, B4GALT4, B4GALT3, B4GALT6, B4GALT5, CHST3, MINPP1, SDC3, SPOCK2, HS3ST4, HS3ST3B1, GPC6, B3GNT3, ST3GAL6, SLC35D2, KERA, B4GALT7 |
1875 | GO:0007265 | 0.00 | 2.14 | 97.28 | 140 | 234 | Ras protein signal transduction | ABCA1, ABL2, ANGPT1, ARHGAP4, ARHGAP5, ARHGAP6, ARHGDIB, ARHGDIG, CALM3, CAMK2A, CAMK2G, CDKN1A, CDKN2A, CHUK, CSF2, CSF2RB, DHCR24, DOK1, HBEGF, DUSP5, DUSP7, DUSP9, ECT2, EDNRA, ERBB2, EREG, FGD1, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FYN, GDI1, GNB1, GRB2, GRIN2A, ARHGAP35, IL2RA, IL2RB, IL2RG, ITGA3, ITGB1, KIT, KPNB1, LIMK1, MARK3, NRAS, PEBP1, PPP2CB, PPP5C, MAPK3, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPRA, RAF1, RALA, RASA2, RB1, RPS27A, RRAS, RREB1, RSU1, SDCBP, ITSN1, SHC1, SOS1, SOS2, SPTA1, SPTB, TRIO, UBB, VAV1, ARHGEF5, FGF23, CUL3, MAPKAPK5, MADD, RFXANK, PEA15, TNK1, CTNNAL1, ARHGEF7, KALRN, DOK2, ARHGEF2, CYTH3, CYTH2, ARHGAP29, ARHGEF6, PSMF1, AATK, ARHGEF17, PSMD6, DENND4B, RBX1, AKAP9, G3BP1, RASA4, FARP1, PSME3, RASGRP2, CDC42EP2, VAV3, ARFGEF2, ARFGEF1, CDC42EP3, STAMBP, GRAP, FRS3, CDC42EP1, RASSF1, AKAP13 |
1876 | GO:0003231 | 0.00 | 2.14 | 24.21 | 35 | 58 | cardiac ventricle development | AP2B1, PRDM1, COL11A1, DNM2, DSP, GATA3, GATA4, GJA5, NRG1, HIF1A, HES1, RBPJ, ISL1, KCNK2, LTBP1, SMAD6, SMAD7, PROX1, PTK7, RXRA, RYR2, SALL1, SCN5A, SMARCD3, SOX4, SOX11, TNNC1, TNNI3, TNNT2, WHSC1, WNT11, TRIP11, HAND1, HAND2, CITED2 |
1877 | GO:0014706 | 0.00 | 2.13 | 22.77 | 33 | 55 | striated muscle tissue development | ATF3, BCL9, KLF5, CACNA1S, CAV2, CDK5, COL19A1, DCN, EEF2, EGR2, EMD, EP300, EYA1, EYA2, GPX1, HLF, HLX, IGFBP5, MEOX2, RB1, RYR1, SOX11, SVIL, NR2F2, XK, EOMES, SAP30, CFLAR, PHOX2B, GTF3C5, HMG20B, VAMP5, VAX1 |
1878 | GO:0071902 | 0.02 | 2.13 | 14.48 | 21 | 35 | positive regulation of protein serine/threonine kinase activity | CCND1, CALM3, CCNC, CCND3, CCNH, CCNT1, CCNT2, CDC6, GADD45A, ACSL1, HSP90AB1, IGF2, LTF, PIM1, PROX1, STIL, SNCA, CAMK1, IQGAP1, CDK5R2, RAPGEF2 |
1879 | GO:0046328 | 0.00 | 2.13 | 32.55 | 47 | 78 | regulation of JNK cascade | AMBP, CDC42, CTGF, GADD45A, EPHA4, EPHB1, ERCC6, ERN1, F2RL1, FCER1A, FLT4, GPS2, IGF1R, IL1A, IL1B, MAP3K5, MEN1, MAP3K11, PARK2, PER1, PTPN1, RAP2A, RPS3, SERPINB3, CCL21, SDCBP, SLAMF1, SYK, TP73, TPD52L1, TRAF2, FZD5, ARHGEF5, FZD4, FZD7, FZD8, TNFSF11, RIPK1, RIPK2, HDAC3, TAOK2, TRAF4, RASSF2, ZEB2, ZMYND11, MAP4K5, FZD10 |
1880 | GO:0055086 | 0.00 | 2.13 | 134.05 | 192 | 322 | nucleobase-containing small molecule metabolic process | ABCA1, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADCYAP1R1, ADORA2A, ADRB2, AK2, AK4, ALDOB, ALDOC, APLP1, AQP1, ARNT, ATP1A2, ATP2B2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP5O, AVP, AVPR2, BAD, BPGM, TSPO, CACNB4, CALCR, CALM3, ENTPD2, CNP, COX4I1, COX8A, COX15, CTNS, DHFR, DLD, DLG1, DLG2, DLG3, DNMT1, DNMT3A, DNMT3B, DTYMK, LPAR1, EDNRA, EDNRB, ENO2, FSHR, GALR1, GAMT, GAPDH, GARS, GCG, GHRH, GHRHR, GLP1R, GNAI3, GNAL, GNAS, GPD1, GRM8, GUCA1A, GUCA1B, GUCA2A, GUCA2B, GUCY1B3, GUCY2C, GUCY2F, GUK1, GUCY2D, HIF1A, HK2, HMGCR, HSPA8, HTR2C, IDH1, IGF1, INS, INSL3, LDHA, LDHC, MDH1, MDH2, NUDT1, NTHL1, NTRK1, NTRK2, OAS1, OAS2, OGDH, OGG1, P2RX7, P2RY11, PDCL, PDC, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, ENPP1, ENPP3, PF4, PFKFB2, PFKFB4, PGAM2, PGD, PGK1, PGK2, PGM1, PPP2R5D, PRKAA1, PRKCA, PRPS2, PRPSAP1, PTGDR, PTGER4, PTGIS, PTHLH, RAF1, RCVRN, RPE, RRM2, SDHC, SNCA, STAT3, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, SULT2A1, SURF1, TAZ, UCN, UNG, UQCRB, UQCRC1, UQCRC2, UQCRH, VEGFA, VIP, VIPR2, WFS1, PDHX, OGT, KCNAB2, PDE5A, SUCLG1, MBD4, KYNU, PAPSS2, PAPSS1, COX5A, AKAP6, TBPL1, TP53I3, ATP5J2, GABBR2, ENTPD4, GUCA1C, HDAC4, SLC25A13, CALCRL, COQ7, RAMP2, RAPGEF3, ATP5H, CAP2, CAP1, ATP5L, AHCYL1, PDE10A, SLC26A1, NUDT3, ECD, ACOT7 |
1881 | GO:1901605 | 0.00 | 2.12 | 54.81 | 79 | 132 | alpha-amino acid metabolic process | ADSS, APC, ARG2, ASNS, ASS1, CKM, DHFR, DHPS, SARDH, DNMT1, DNMT3A, DNMT3B, FAU, GAMT, RPL10A, ODC1, P4HA1, PSPH, PYCR1, ALDH18A1, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, SHMT2, SLC6A8, SMS, STAT5B, TYMS, GGH, P4HA2, RPL14, RPL23, PTDSS1, NR1H4, GLYAT, CRTAP, PRDX4, AHCYL1, SERINC3, RPL35 |
1882 | GO:0045944 | 0.00 | 2.12 | 210.37 | 299 | 505 | positive regulation of transcription from RNA polymerase II promoter | ACVR1, ACVR1B, ACVR2A, ACVRL1, ADRB2, AHR, AKT2, APBB1, ARF4, PHOX2A, ARNT, ARNTL, ATF3, RERE, ATOH1, ATRX, BACH1, BCL3, BCL9, BMP4, BMP6, BMPR1A, BMPR2, BRCA1, KLF5, CBFB, CCNC, CCNH, CCNT1, CCNT2, CD3D, CD28, TNFSF8, CD40, CDK8, CDK9, CDKN2A, CDX1, CDX4, CEBPE, CEBPG, CGA, CHUK, ATF2, CRX, CUX1, DCN, DDX3X, DDX5, DLX3, ARID3A, E2F4, E2F5, EBF1, S1PR1, EGR2, ELF1, ELF3, ELK1, ELK3, EN1, ERCC3, ESR1, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV4, ETV5, ETV6, EVX1, EYA1, EZH1, F2RL1, FGF1, FLI1, NR5A1, GABPA, GALR1, GATA3, GATA4, GATA6, GCG, KAT2A, NR6A1, GDNF, GTF2F1, H2AFZ, HCLS1, HEXB, HGF, NRG1, HHEX, HMGA1, NR4A1, ONECUT1, HOXC11, HOXD8, HES1, IFI16, IFNG, IGF1, IGF2, IHH, IL1A, IL1B, IL10, FOXK2, INSIG1, ITGA6, IRF1, IRF2, IRF5, ISL1, JUN, JUNB, JUND, ABLIM1, LMO1, LUM, EPCAM, SMAD3, SMAD7, MEIS1, MEN1, MEOX2, CIITA, FOXO4, CITED1, PPP1R12A, NRF1, NRL, YBX1, NTF3, SIX6, OTX1, OTX2, P2RY1, SERPINE1, PARK2, PAX1, PAX2, PAX9, PBX1, PCK1, PER1, PF4, PGR, PRRX1, PPP3R1, PRKD1, MAPK3, PROX1, PSMC1, PSMC3, PSMC4, PSMC5, RAF1, RARA, RARB, RB1, ARID4A, RBL1, RELB, REST, RFX3, RFX4, RPS6KA1, RPS6KA3, RPS27A, SAFB, SALL1, ATXN7, SHH, SIX1, SIX3, SLC9A1, SLC11A1, SMARCA2, SMARCA4, SMARCC1, SOX1, SOX2, SOX4, SOX5, SOX9, SOX10, SOX11, SOX12, SP1, SP3, SREBF1, SRF, STAT3, STAT4, STAT5B, SUPT4H1, T, TAF2, TAF7, TAL1, TBL1X, HNF1A, NR2E1, TNFRSF1A, TOP2A, TP73, NR2C2, TRPS1, TSC2, TWIST1, UBB, UBE3A, UCN, NR1H2, VDR, WNT1, WNT2, ZIC1, CNBP, ZSCAN21, ZNF148, PAX8, FZD5, MAFK, CSRP3, FOSL1, NRIP1, EOMES, FZD8, UTF1, OGT, ITGA8, IKBKG, CAMK1, STK16, TNFSF11, RFXANK, TP63, TNKS, RIPK1, RIPK2, HDAC3, KAT2B, NR1I2, BUD31, PHOX2B, FUBP3, RPS6KA4, CBFA2T2, ARHGEF2, CCPG1, RPS6KA5, ITGB1BP1, KLF4, HMGN3, HAND1, EIF2AK3, FHL5, HAND2, ONECUT2, CLOCK, HDAC4, ZEB2, RNF10, NR1I3, NR1H4, NR2E3, CEBPZ, TRIM28, COQ7, FSTL3, STAG1, TNIP1, IKZF1, KLF2, CITED2, RAPGEF3, RBM14, SLC30A9, BATF, USP16, ERLIN1, RBCK1, ARID3B, DMRT2, CTCF, TBR1, STAG2, SIX2, RAI1, RUVBL2, ARID5A, SLC38A3, WWP2, ERLIN2, PSIP1, KLF12 |
1883 | GO:0044772 | 0.01 | 2.12 | 21.40 | 31 | 52 | mitotic cell cycle phase transition | APC, BUB1, BUB1B, CDC20, CDC27, CENPE, CSNK2A1, CSNK2A2, DDB1, DUSP1, EPS8, ERCC3, MAD2L1, RPL24, UBE2D1, XPC, ZNF207, CDC14A, CDC23, CDC16, CTDP1, ZW10, BUB3, MAD2L1BP, KNTC1, DLGAP5, ANAPC10, MAD2L2, UBE2C, CIT, PHB2 |
1884 | GO:0006694 | 0.01 | 2.12 | 18.69 | 27 | 45 | steroid biosynthetic process | ACLY, NR0B1, APOA1, APOA4, SCARB1, CFTR, CYP11B1, CYP51A1, DHCR24, CYB5R3, FDFT1, FDPS, FDXR, HMGCR, HMGCS1, HMGCS2, HSD11B1, HSD17B3, PBX1, SQLE, SRD5A1, CNBP, HSD17B6, GGPS1, ACAA2, EBP, C14orf1 |
1885 | GO:0040008 | 0.00 | 2.12 | 36.64 | 53 | 89 | regulation of growth | ACTL6A, AES, BBS4, C3, CCNB1, DIO3, E4F1, FGF8, GAMT, GAP43, GAS6, GATA4, GATA6, GHRH, GHRHR, GHSR, HLX, IGF2, RBPJ, IHH, ING2, PPIB, PROX1, PTGER4, RAG2, SHC1, SIX1, SOD1, STAT3, STAT5B, VIL1, EZR, WFS1, WNT2, WRN, ZP3, ATRN, CREG1, HDAC3, SGPL1, SOCS3, LATS1, SOCS6, VPRBP, BCL2L11, IKZF1, UBE2E3, ENOX2, CARM1, AGR2, CSPG5, RUVBL2, BRD8 |
1886 | GO:0007275 | 0.00 | 2.12 | 490.82 | 686 | 1281 | multicellular organism development | AAMP, AARS, ABAT, ACHE, ACP2, ACP5, ACTA2, ACTB, ACTG1, ACTL6A, ACTN1, ADCY1, ADORA1, ADORA2A, ADRA1B, ADRBK1, AP2A1, AP2B1, AEBP1, AES, AK2, AK4, AKT2, ALAS2, ALDH9A1, ALDH3A2, ALDOB, ALK, AMBN, AMELY, ANPEP, ANXA2, APLP1, APLP2, APOA4, APRT, SHROOM2, AQP5, AQP6, ARF4, ARHGAP5, RHOH, PHOX2A, STS, ARSE, ASGR2, ASNS, ASTN1, ATF3, RERE, ATP2B1, ATP5F1, ATP5J, ATP7B, ATR, AVPR2, BBS2, BCHE, BCL3, BCL9, TNFRSF17, BFSP1, BID, BMP8B, BMX, ZFP36L2, BST2, BTD, C1QB, DAGLA, CACNA1F, CACNA1S, CACNB4, CALM3, CALU, CAMK2A, CAMK2G, CAPN1, CASP5, CASP9, CASP10, CAV2, CBFB, SERPINH1, CCIN, CCK, CD3D, CD4, CD8A, CD9, TNFRSF8, TNFSF8, CD72, CDH1, CDK4, CDKN2C, CDO1, CEBPE, CEBPG, CENPE, CHD2, CHRM1, CHRM3, CHUK, TBCB, AP2M1, AP2S1, CLCN2, CLU, TPP1, CLN5, CLTA, ACKR2, CMKLR1, CNP, COL4A4, COL4A5, COL6A2, COL6A3, COL9A1, COL10A1, COL19A1, COX6B1, COX7B, CR2, ATF2, CRYAB, CRYBA1, CRYBA4, CRYGB, CSF2RB, CSNK2A1, CSNK2A2, VCAN, CSPG4, CSRP2, CTF1, CTNNA2, CTNS, CTNND1, CTNND2, CYLC1, DAZ1, DBI, DCX, DDX1, DFNA5, DHFR, DHODH, DIAPH2, DLG2, DLG3, DLX3, DNM1, DNASE1L2, DNASE2, DNMT1, ATN1, RCAN1, DSP, HBEGF, ECM2, DUSP7, DUSP9, DYRK1A, E2F4, E2F5, EBF1, GPR183, TYMP, EDN3, PHC1, PHC2, EEF2, EFNA3, EFNA4, EIF2B1, EIF4A1, ELAVL1, ELAVL3, ELK3, ELN, EML1, EMD, EMP1, ENPEP, SLC29A1, EPB42, EPHA5, EPHA8, EYA4, ERG, ETV1, ETV6, EVC, EXTL1, EYA3, EZH1, F2RL1, F7, FABP7, ACSL3, FAP, FCER1G, FECH, FGA, FGD1, FGF6, FGF11, FGFR4, FLG, FLI1, FLII, FLNA, FLT4, AFF2, GAA, GABRA4, GABRB2, GAP43, BLOC1S1, GFRA1, GHRH, GIP, GJA4, GJB1, GLRA2, GLRB, GLUD1, GNAT1, GNAT2, GNB1, GNGT1, GNRH2, GNRHR, GPD2, GPLD1, GPM6A, GRIN2A, CXCL1, GSS, HIST1H1T, H3F3B, HAS2, HCCS, HEXB, HIC1, HIVEP2, HK2, HLF, HMBS, HMGCL, NR4A1, HMX1, HNF4G, ONECUT1, HPGD, HPRT1, AGFG1, HSPA8, HSP90AA1, HSP90AB1, IAPP, IFI16, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGF2, IL2RB, IL2RG, TNFRSF9, IL18, IMPDH1, IMPDH2, INS, INSL4, ITGA1, ITGA9, ITGAX, IVL, JARID2, JUP, KCNA1, KCNA2, KCNJ8, KCNJ10, KCNK3, KCNQ1, KIF5A, KLKB1, KRT2, KRT13, KRT16, LDHA, LIM2, ABLIM1, LTBP1, LUM, MAL, MAP6, MARK3, MATN3, RAB8A, MEN1, MFGE8, MGMT, ATXN3, MKI67, DRG1, SEPT2, SLC11A2, NRF1, NRL, NRTN, NTN3, ODC1, ODF1, ODF2, OGDH, OGN, OMP, OPCML, OPHN1, SIX6, CLDN11, OVOL1, OXCT1, P2RY1, PEBP1, PAEP, PAFAH1B2, PAFAH1B3, CNTN3, PCDH9, PCOLCE, CDK16, PDE1B, PDPK1, PENK, ATP8B1, PHEX, PHF2, SERPINI1, PIM1, PIK3CG, PIP4K2A, PLN, PPIB, PPL, PPP2R5D, PPP5C, PPT1, PRCP, PRKCG, PRKCQ, PRKG1, PRM2, PRPS2, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTH1R, PTPN3, PTPN14, PTPRA, PTPRB, PTPRJ, RAD1, PURA, QARS, QDPR, RAC2, RAF1, RAG2, RASA2, PRPH2, RELB, RHAG, RPGR, RPL22, RPL24, RPS4X, RPS4Y1, RPS6KA1, RPS6KA2, RPS6KA3, RPS19, RPS27A, RS1, RYR1, S100A1, SORT1, S100A4, S100A6, S100A8, S100A9, SAT1, SATB1, SCN2B, SCN3A, SCN5A, SCN8A, SCN10A, SRSF4, SRSF5, SFTPB, SGCB, SGCD, ITSN1, SHB, SHC1, SIAH1, SIAH2, SLC2A2, SLC5A3, SLC6A11, SLC8A3, SLC9A1, SLC12A1, SLC34A1, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCC2, SMARCE1, SMPD1, SOX12, SPAST, SPG7, SPN, SPRR1B, SPRR2A, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3, SPTA1, SPTB, SRPK2, SSTR2, SSTR3, STRN, STXBP1, STXBP3, SVIL, TACC1, TAGLN, TAZ, TMOD1, CLEC3B, TNFAIP2, TNFRSF1B, TNNC1, TNNI3, TNNT2, TNP2, TPD52, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TSG101, TUFT1, TULP1, TNFRSF4, UCN, UFD1L, UGT8, UPK2, UPK3A, USF2, USH2A, VCL, EZR, WEE1, WFS1, ZFX, ZNF3, ZNF7, ZNF22, ZNF45, ZNF74, ZNF148, VEZF1, PTP4A1, RNF103, SCG2, EPM2A, MAFK, CSRP3, CUL5, SLC7A5, MADCAM1, DPF1, PICALM, FZD8, FZD9, BCAR3, BFSP2, LTBP4, NR0B2, DOC2A, CUL4B, CUL1, ATRN, SORBS2, CNTNAP1, KCNAB2, PIR, KLF7, CDK13, UNC5C, DYNLL1, BECN1, PEA15, JRKL, EDF1, EED, ADAM19, ADAM9, TNFRSF6B, TNFRSF18, RGS9, TNFRSF10D, TNFRSF10B, TNFRSF10A, CREG1, IL18R1, CDKL1, SAP30, LIN7A, IQGAP1, NRP2, CFLAR, ARHGEF7, VNN2, EIF2B3, SGCE, BSN, CDK5R2, RPS6KA4, KALRN, RNF8, BAZ1B, PAPSS2, PAPSS1, ATP6V0D1, INA, KRT75, AIFM1, SYNGR3, DYRK1B, EXO1, DCLK1, ZMYM6, AURKB, VAPA, DHRS3, RPS6KA5, PDLIM7, TRIP11, GTF3C5, NRXN2, RECQL4, QKI, CHST3, ATG5, ONECUT2, PSMF1, ADAMTS4, GAL3ST1, BAG3, CXCL14, MINPP1, FEZ2, IQCB1, ZNF516, UTP14C, VPRBP, FAM65B, SNPH, RAPGEF5, SNX17, SPOCK2, RB1CC1, SPATA2, ZBTB24, GAB2, FARP2, PSMD6, RBX1, DOPEY2, PTBP3, KCNE2, NR2E3, RANBP9, ABCB6, COX17, PTPRU, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN2, ARPC2, FEM1B, FRY, RASA4, FARP1, WASF2, PSME3, DHRS2, CALCRL, PRG4, SIGMAR1, SPON2, ARIH2, FAM3C, VAV3, GPNMB, TACC3, SLC9A6, CAP2, CAP1, UNC13B, CHERP, BATF, ARPC1A, ARFGEF1, DPYSL4, TACC2, TRIM3, HEXIM1, TXNIP, KLF1, CSPG5, EBP, FUT9, RAI1, CHL1, VAMP5, CPLX2, FRS3, ARID5A, MALT1, PRDX3, EHD1, TMED10, SLC38A3, SLC27A4, RAB35, WWP1, KERA, ESM1, BVES, SOX21, TREH, FZD10, TUSC2 |
1887 | GO:0048729 | 0.00 | 2.11 | 124.55 | 178 | 299 | tissue morphogenesis | ABL2, ACVR1, ACVRL1, AGTR2, ALDH1A3, AREG, BAX, BBS4, BCL2, BMP4, BMPR2, CA2, CASP8, CAV3, CD44, CDC42, CHUK, COL3A1, COL5A1, COL11A1, CTSV, CTSZ, DAB2, DLG1, DLG3, DSP, HBEGF, S1PR1, EDNRA, EFNB2, CELSR2, EPHA2, EPHA4, EPHA7, ESR1, ETV2, ETV4, ETV5, EXT2, EYA1, EYA2, GPC4, FGF1, FGF3, FGF7, FGFR3, FOXD1, GATA3, GATA4, KAT2A, GDNF, B4GALT1, GPC3, GNAT2, GRB2, ARHGAP35, GRSF1, HGF, NRG1, HHEX, HIF1A, FOXA2, HOXD11, HES1, TNC, IGF1, IGF1R, IGFBP5, IHH, IL10, ILK, ITGA2, ITGA3, ITGA5, ITGB1, ITGB4, KDR, KRAS, KRT16, LAMA5, LLGL2, TACSTD2, SMAD1, SMAD7, CITED1, OPA1, PAX2, PBX1, PCDH8, PFN1, PGF, PGR, PPP1CA, PRKACB, PRKAR1A, PRKX, PSPN, PROX1, PTCH1, PTHLH, PTK7, PTN, PTPRM, RAC1, RALA, RARA, RPGR, RREB1, RS1, RXRA, RYK, RYR2, SALL1, SCNN1B, SDC4, SHH, STIL, SIX1, SIX3, SLC12A2, SOX2, SOX4, SOX10, SOX11, SPINT1, SRF, ST14, T, TAL1, TNNC1, TNNI3, TNNT2, TSC1, TSC2, TULP3, KDM6A, VCL, VDR, VEGFA, VEGFC, WNT1, WNT2, WNT2B, ZIC2, PAX8, FZD5, FZD3, EOMES, FZD6, FZD7, FOXN1, ITGA8, TP63, CHRD, NUMB, HESX1, PROM1, ALDH1A2, BCL10, SOCS3, KLF4, SLIT2, SLC9A3R1, SEMA3E, ZEB2, GPC6, FEM1B, TRIM28, COQ7, IRX5, IKZF1, SEMA3A, SEC24B, DEAF1, SPINT2, SIX2, GLMN, PHB2 |
1888 | GO:0030029 | 0.00 | 2.11 | 69.54 | 100 | 168 | actin filament-based process | ACTG1, ACTN4, ACTN1, ANG, ANXA1, AQP1, RND3, ARHGDIB, BCL2, CASQ2, CDC42, CNN1, CNN3, CTNNA1, CXADR, DBN1, DIAPH1, DIAPH2, DPYSL3, EMP2, EPB41, EPB41L2, FGD1, FGF7, FLII, FLNA, GHSR, CXCL1, INPPL1, INSRR, ITGB1, ITGB5, KCNA5, KCNE1, KCNQ1, KIT, KRAS, KRT19, LLGL2, ATXN3, MYO1B, OPHN1, PAWR, PDPK1, PRKAR1A, PRKCI, PRKCZ, PRKG1, PTK7, PTPN1, RAB13, RAC2, RAC3, RALA, RAN, RAP2A, S100A9, SCN2B, SCN4B, SDCBP, SELE, SHC1, SNTA1, SRF, TNNC2, TNNI2, TNNI3, TNNT1, TPM2, CLRN1, EZR, VIM, CORO2A, CUL3, SORBS2, CDC42BPA, DYNLL1, CFLAR, ARHGEF2, PDLIM7, CYTH2, S1PR2, TRIP10, TAOK2, SLC9A3R1, BCAR1, CDC42BPB, NUP155, ARHGEF17, ELMO1, FARP2, KCNE2, ABI1, FRY, CORO2B, MAD2L2, CAP1, SORBS1, CAPN10, KPTN |
1889 | GO:0001701 | 0.00 | 2.11 | 42.37 | 61 | 102 | in utero embryonic development | ACVR1, ACVR1B, ACVRL1, ADAM10, ADAR, ADD1, ANGPT1, BCL2L1, BMPR1A, BTF3, C5, CCNB1, DDX5, DSC3, EDNRA, EMX1, FUT8, GABPA, GATA3, GATA4, GATA6, KAT2A, HHEX, FOXA2, IHH, INSL3, ITGB1, SMAD3, YBX1, OCRL, P2RY2, PTCH1, PTPRR, RBBP6, RCN1, RXRA, SRSF1, STIL, SOX5, SOX10, SP2, TWIST1, KDM6A, VEGFA, XRCC2, SLC30A1, FOSL1, USP9X, CUL4A, COPS3, EIF2S2, CCNB2, SLIT2, HAND2, APBA3, BCL2L11, COL4A3BP, COQ7, SPEG, KLF2, SLC34A2 |
1890 | GO:0051896 | 0.05 | 2.11 | 10.40 | 15 | 25 | regulation of protein kinase B signaling | CAV3, CRYBA1, DLG1, EPHA2, RAPGEF1, NTRK2, RRAS, SFRP5, STK11, TSC2, INPP4B, KLF4, SLC9A3R1, PDCD6, RNF41 |
1891 | GO:0045667 | 0.03 | 2.11 | 12.48 | 18 | 30 | regulation of osteoblast differentiation | APC, AREG, CDK6, DDX5, IGFBP5, SMAD3, MEN1, CITED1, PRKACA, PTCH1, SNAI2, SOX2, TWIST1, FGF23, CHRD, HAND2, HDAC4, RASSF2 |
1892 | GO:0002761 | 0.01 | 2.11 | 16.68 | 24 | 40 | regulation of myeloid leukocyte differentiation | APC, ATP6AP1, BGLAP, CA2, CAMK4, CASP8, CCR1, FSHR, GNAS, HCLS1, IFNG, JUN, KITLG, PF4, PRKCA, RB1, TAL1, KLF10, TYROBP, OGT, TNFSF11, RIPK1, RASSF2, IKZF1 |
1893 | GO:1903363 | 0.00 | 2.10 | 25.04 | 36 | 60 | negative regulation of cellular protein catabolic process | ANXA2, APC, ATM, BUB1, BUB1B, CCNB1, CDC20, CDC27, CDKN2A, CENPF, CSNK2A1, CSNK2A2, DUSP1, HSP90AB1, MAD2L1, OPHN1, PRKCG, SDCBP, SHH, SMARCC1, UBE2D1, WNT1, ZNF207, CDC23, CDC16, USP14, ZW10, BUB3, PSMF1, BAG5, RGP1, ANAPC10, MAD2L2, GIPC1, USP19, UBE2C |
1894 | GO:0014033 | 0.00 | 2.10 | 22.95 | 33 | 55 | neural crest cell differentiation | ACVR1, BMPR1A, EDN3, EDNRA, EDNRB, GDNF, NRG1, HIF1A, HES1, ISL1, LAMA5, KITLG, NRTN, MAPK3, SEMA3F, SHH, SNAI2, SOX9, SOX10, SOX11, TWIST1, SEMA3B, SEMA7A, ALDH1A2, PHOX2B, HAND2, SEMA3E, ZEB2, SEMA3A, SEMA6C, SEMA6B, SEMA4F, SEMA4B |
1895 | GO:0007569 | 0.01 | 2.10 | 16.68 | 24 | 40 | cell aging | ARNTL, ATM, ATR, BCL2, BGLAP, BMPR1A, BRCA2, CDK6, CDKN1A, CDKN2A, HSD17B10, HMGA1, ICAM1, ILK, ING2, OPA1, SERPINE1, SOD1, SRF, TWIST1, WNT1, MAPKAPK5, NUAK1, ZNF277 |
1896 | GO:0001942 | 0.01 | 2.10 | 18.78 | 27 | 45 | hair follicle development | AARS, ACVR1B, APC, BCL2, CDC42, CDH3, CTSV, DBI, DNASE1L2, EDA, FGF7, GNAS, IGFBP5, RBPJ, KRT84, LAMA5, SHH, SNAI1, SOX9, FZD3, FZD6, FOXN1, TP63, TRADD, EDAR, SPINK5, SOX21 |
1897 | GO:0022404 | 0.01 | 2.10 | 18.78 | 27 | 45 | molting cycle process | AARS, ACVR1B, APC, BCL2, CDC42, CDH3, CTSV, DBI, DNASE1L2, EDA, FGF7, GNAS, IGFBP5, RBPJ, KRT84, LAMA5, SHH, SNAI1, SOX9, FZD3, FZD6, FOXN1, TP63, TRADD, EDAR, SPINK5, SOX21 |
1898 | GO:0035914 | 0.05 | 2.10 | 10.42 | 15 | 25 | skeletal muscle cell differentiation | ATF3, BCL9, KLF5, EEF2, EGR2, EMD, HLF, RB1, SOX11, EOMES, SAP30, PHOX2B, GTF3C5, HMG20B, VAX1 |
1899 | GO:0002456 | 0.01 | 2.10 | 16.69 | 24 | 40 | T cell mediated immunity | CD8A, CLC, CD55, DLG1, EMP2, GATA3, ICAM1, IFNA2, IL1B, CD46, P2RX7, PRKCZ, PVR, RAB27A, XCL1, SLC11A1, SPN, TRAF2, TNFSF4, ZP3, FZD5, KDM5D, STX11, MALT1 |
1900 | GO:0019054 | 0.01 | 2.10 | 16.69 | 24 | 40 | modulation by virus of host process | BAD, BCL2L1, CD4, KPNA1, KPNB1, KPNA4, KPNA5, NTRK3, NUP88, NUP98, PARK2, EIF2AK2, RANBP2, NUP214, AAAS, VAPB, VAPA, NUP155, NUP93, BCL2L11, ATG7, NUP50, CPSF4, NUPL2 |
1901 | GO:0042490 | 0.01 | 2.10 | 16.69 | 24 | 40 | mechanoreceptor differentiation | ATOH1, ATP2B2, BMP4, CUX1, DFNA5, FGFR3, GABRB2, GFI1, HES1, RBPJ, NTF3, NTF4, NTRK1, NTRK2, NTRK3, ATP8B1, RAC1, SDC4, SOD1, USH2A, CLRN1, IFT88, SLC9A3R1, SEC24B |
1902 | GO:0009145 | 0.03 | 2.10 | 12.52 | 18 | 30 | purine nucleoside triphosphate biosynthetic process | ADK, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, LDHC, STAT3, SURF1, ATP5J2, SLC25A13, ATP5H, ATP5L |
1903 | GO:0030512 | 0.03 | 2.10 | 12.52 | 18 | 30 | negative regulation of transforming growth factor beta receptor signaling pathway | CAV2, DNM2, FBN1, ONECUT1, LTBP1, SMAD3, SMAD6, SMAD7, PDPK1, PPM1A, PPP1CA, RPS27A, UBB, WNT1, ZFYVE9, ONECUT2, ADAMTSL2, STRAP |
1904 | GO:0032413 | 0.03 | 2.10 | 12.52 | 18 | 30 | negative regulation of ion transmembrane transporter activity | ATP1A2, CALM3, CASQ2, CAV3, GRK6, GSTM2, KCNE1, KCNQ1, PLN, PRKCE, SLN, SUMO1, SLC9A3R1, GSTO1, OXSR1, KCNE2, KCNE3, TRDN |
1905 | GO:0070302 | 0.00 | 2.09 | 40.48 | 58 | 97 | regulation of stress-activated protein kinase signaling cascade | AMBP, CAV3, CDC42, CTGF, GADD45A, DLG1, EPHA4, EPHB1, ERCC6, ERN1, F2RL1, FCER1A, FLT4, GPS2, HGF, HMGCR, PRMT1, IGF1R, IL1A, IL1B, MAP3K5, MEN1, MAP3K11, PARK2, PER1, MAPK3, EIF2AK2, PTPN1, RAP2A, RPS3, SERPINB3, CCL21, SDCBP, SLAMF1, SYK, TP73, TPD52L1, TRAF2, VEGFA, EZR, FZD5, ARHGEF5, FZD4, FZD7, FZD8, TNFSF11, RIPK1, RIPK2, HDAC3, TAOK2, TRAF4, RASSF2, ZEB2, STK25, ARL6IP5, ZMYND11, MAP4K5, FZD10 |
1906 | GO:0043588 | 0.00 | 2.09 | 27.87 | 40 | 67 | skin development | AARS, ACVR1B, ALOX12, APC, STS, BCL2, COL1A1, COL3A1, COL5A1, COL5A2, CTSV, DBI, DHCR24, EDA, FGF7, GNAS, IGFBP5, ITGA6, ITGA2, ITGA3, ITGB4, JUP, KRT1, LAMA5, OVOL1, RYR1, SHH, SNAI1, SOX9, SRF, FZD3, FZD6, PTCH2, TRADD, ADAMTS2, ABCB6, EDAR, SLC27A4, SPINK5, SOX21 |
1907 | GO:0002443 | 0.01 | 2.09 | 21.57 | 31 | 52 | leukocyte mediated immunity | BCL3, C1QBP, SERPING1, C1QA, C1QB, C1QC, C1S, C5, C8B, CD8A, CD74, CEBPG, CLU, CR2, CD55, DBH, DLG1, EMP2, ERCC1, GATA3, KLRC2, KLRD1, CD46, RAB27A, SLC11A1, KDM5D, BCL10, RNF8, EXO1, BATF, CORO1A |
1908 | GO:0045664 | 0.01 | 2.09 | 22.21 | 32 | 54 | regulation of neuron differentiation | BIN1, CACNA1A, CDC20, CHN1, CHRNB2, DBN1, DNM2, CTTN, EPHB3, EYA1, GATA3, GRID2, NTF3, NTF4, PRRX1, KLK6, RAP2A, SDC2, SIX1, SLIT1, SLIT3, SNAP25, SOX5, XK, YWHAG, EOMES, KLF4, NREP, PQBP1, OLFM1, PDLIM5, TBR1 |
1909 | GO:0072511 | 0.00 | 2.08 | 90.56 | 129 | 217 | divalent inorganic cation transport | ADCYAP1R1, ADRB2, ANXA5, ANXA6, ATP1A2, ATP2A1, ATP2B1, ATP2B2, BAX, BCL2, BMP4, TSPO, CACNA1A, CACNA1B, CACNA1E, CACNA1F, CACNA1S, CACNA2D1, CACNB4, CACNG1, CALM3, CAMK2A, CAMK2G, CASQ2, CAV3, CD4, CDK5, CHRNB2, CLCA1, CCR1, CCR5, CTGF, CYBA, CYP27B1, DIAPH1, EDNRA, F2R, FYN, GAS6, GCG, GIF, GJA4, GPM6A, XCR1, FFAR1, GRIN2A, GSTM2, HRC, HTR2C, ICAM1, IGF1, IL13, ITGAV, ITPR1, ITPR2, ITPR3, KCNJ2, KCNN4, SLC11A2, NTSR1, P2RX3, P2RX4, P2RX7, PAWR, PDE4B, PDE4D, PDPK1, PIK3C2A, PIK3CG, PLN, PRKACA, PRKCB, PRKCE, PRKD1, PTPN6, RCVRN, RYR1, RYR2, RYR3, S100A1, CCL21, XCL1, SEMG1, SLC8A1, SLC8A3, SLC9A1, SLC11A1, SLN, SNCA, SPINK1, STC1, TPT1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, SUMO1, UCN, VDR, TRPV1, WFS1, SLC30A1, SLC30A2, ZP3, TUSC3, CUL5, CD84, HAP1, RGN, SLC24A1, GSTO1, AKAP6, ATG5, KCNE2, KCNE3, CALCRL, RAMP2, RAMP3, TRDN, CACNG2, RAPGEF3, SLC30A9, CREB3, CHERP, CLDN16, CACFD1, IL1RAPL1, CORO1A |
1910 | GO:0060560 | 0.00 | 2.08 | 41.27 | 59 | 99 | developmental growth involved in morphogenesis | ARHGAP4, BMPR2, CDK5, DCC, DCX, DNM2, S1PR1, EFNA5, EMX1, CTTN, EPHA7, GOLGA4, NRG1, ILK, ITGB1, LIMK1, NRCAM, NTRK3, PARK2, PRKCZ, PTHLH, RNF6, SALL1, SEMA3F, SLC12A2, SLIT1, SLIT3, SRF, AURKA, CDKL5, STK11, SYT1, SYT4, TNR, VCL, VEGFA, SEMA3B, RND2, USP9X, SEMA7A, RAB11A, IQGAP1, NRP2, CPNE1, DCLK1, SLIT2, CPNE6, AATK, RIMS2, SEMA3E, IST1, SEMA3A, OLFM1, SLC9A6, SEMA6C, SEMA6B, SEMA4F, SEMA4B, TWF2 |
1911 | GO:1902680 | 0.00 | 2.08 | 303.66 | 425 | 729 | positive regulation of RNA biosynthetic process | ACVR1, ACVR1B, ACVR2A, ACVRL1, ADRB2, AGTR2, AHR, AKT2, ALK, ANXA3, APBB1, ARF4, PHOX2A, ARNT, ARNTL, ATF3, ATF4, RERE, ATOH1, ATRX, BACH1, BCL3, BCL9, BMP4, BMP6, BMPR1A, BMPR2, BRCA1, BRCA2, BRDT, KLF5, BTK, CAMK4, CAMK2A, CAT, RUNX2, CBFB, CCNC, CCNE1, CCNT2, CD3D, CD28, CD80, CD86, TNFSF8, CD38, CD40, CDH1, CDK8, CDKN2A, CDX1, CDX2, CDX4, CEBPE, CEBPG, CGA, CHUK, CLU, COL1A1, ATF2, CREBL2, CRX, CTH, CUX1, DAB2, DCN, DDX3X, DDX5, DLX3, DLX5, DNM2, ARID3A, E2F4, E2F5, EBF1, EDA, S1PR1, EGR2, ELF1, ELF3, ELK1, ELK3, EN1, EPHA5, ERBB2, ERCC6, ESR1, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV4, ETV5, ETV6, EVX1, EYA1, EZH1, F2R, F2RL1, FGF1, FGF7, FLI1, NR5A1, GABPA, GALR1, GATA3, GATA4, GATA6, GCG, KAT2A, NR6A1, GDNF, H2AFZ, HAS3, HCLS1, HEXB, HGF, NRG1, HHEX, HIF1A, HMGN1, HMGA1, NR4A1, FOXA2, HNF4G, ONECUT1, HOXC11, HOXD8, PRMT2, HES1, ICAM1, IFI16, IFNA2, IFNG, IGF1, IGF2, RBPJ, IHH, IL1A, IL1B, IL10, FOXK2, ILK, ING2, INS, INSIG1, IRAK1, ITGA6, IRAK2, IRF1, IRF2, IRF5, ISL1, JUNB, JUND, JUP, KIT, KRAS, ABLIM1, LMO1, LTF, LUM, EPCAM, SMAD1, SMAD3, SMAD7, MEIS1, MEN1, MEOX2, CIITA, AFF1, FOXO4, CITED1, PPP1R12A, NRF1, NRL, YBX1, NTF3, NTRK1, DDR2, SIX6, OTX1, OTX2, P2RY1, SERPINE1, PARK2, PAX1, PAX2, PAX9, PBX1, PCK1, PER1, PF4, PGR, PHB, PHF2, PRRX1, PPM1A, PPP3R1, PRKCB, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK3, EIF2AK2, PROX1, RELN, PSMA6, PSMC1, PSMC3, PSMC4, PSMC5, PTCH1, RAF1, RAN, RARA, RARB, RB1, ARID4A, RBL1, RELB, REST, RFX3, RFX4, RFXAP, RNF6, RPS3, RPS6KA1, RPS6KA3, RPS27A, RREB1, RXRA, RXRG, S100A8, S100A9, S100A12, SAFB, SALL1, ATXN7, SHH, SIX1, SIX3, SLC9A1, SLC11A1, SMARCA1, SMARCA2, SMARCC1, SMARCC2, SMARCD3, SNAI1, SOX1, SOX2, SOX4, SOX5, SOX9, SOX10, SOX11, SOX12, SP3, SP100, SREBF1, SRF, SRY, STAT3, STAT4, STAT5B, T, TAF2, TAF7, TAL1, TBL1X, TBP, HNF1A, NR2F2, NR2E1, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C2, TRAF1, TRAF2, TRPS1, TSC2, TWIST1, UBB, UBE2V1, UBE3A, UBTF, UCN, NR1H2, USF1, USF2, VDR, VEGFA, WNT1, WNT2, WNT11, YWHAH, ZIC1, ZIC2, ZNF711, CNBP, ZSCAN21, TRIM25, ZNF148, ZBTB17, ZP3, ZXDA, LRP8, PAX8, FZD5, BRPF1, MAFK, ARHGEF5, CSRP3, FOSL1, FGF23, NRIP1, PICALM, EOMES, FZD4, FZD7, FZD8, UTF1, OGT, ITGA8, IKBKG, CAMK1, STK16, TNFSF11, KLF7, RFXANK, TP63, TNKS, TRADD, EDF1, RIPK1, RIPK2, TRIM24, CFLAR, HDAC3, KAT2B, NR1I2, BUD31, BCL10, PHOX2B, FUBP3, RPS6KA4, TNFSF18, BAZ1B, CBFA2T2, DYRK1B, ARHGEF2, CCPG1, RPS6KA5, ITGB1BP1, KLF4, HMGN3, TRIP4, HAND1, EIF2AK3, FHL5, HAND2, ONECUT2, NR1D1, CLOCK, CREB5, ZNF516, HDAC4, BCLAF1, SERTAD2, ZEB2, RNF10, NR1I3, NR1H4, NR1D2, NR2E3, YAF2, CEBPZ, TRIM28, ALYREF, RNF41, COQ7, FSTL3, STAG1, TNIP1, IKZF1, TRIM22, KLF2, CITED2, RAPGEF3, RBM14, MAD2L2, SLC30A9, TRIM38, CREB3, DEAF1, BATF, USP16, ERLIN1, RBCK1, ARID3B, TRIM16, DMRT2, KLF1, CTCF, TBR1, STAG2, SIX2, RAI1, RUVBL2, ARID5A, MALT1, PRDX3, SLC38A3, PIM2, WWP2, ERLIN2, PSIP1, CHEK2, KLF12, PHB2 |
1912 | GO:0048489 | 0.00 | 2.08 | 27.96 | 40 | 67 | synaptic vesicle transport | AMPH, ARF1, CACNA1A, CDK5, AP3S1, DNM1, DNM2, BLOC1S1, GRN, OPHN1, P2RX7, PARK2, PFN2, SEPT5, RAB3A, RAB27A, RAP1A, ITSN1, SNAP25, SNCA, STXBP1, SYN1, SYT1, DOC2A, AP3B1, CADPS, STX11, SNAP23, LIN7A, SYNJ1, AP3D1, SNAP29, RIMS2, SNPH, RIMS3, AP3S2, UNC13B, CPLX2, CPLX1, AP3M2 |
1913 | GO:0051250 | 0.00 | 2.08 | 27.96 | 40 | 67 | negative regulation of lymphocyte activation | ANXA1, ATM, AXL, PRDM1, BMP4, CBLB, CD74, CDKN2A, CTLA4, CYLD, DLG1, DTX1, ERBB2, FLT3, HLX, IFNA2, IHH, IL2RA, IL10, IDO1, INHA, IRF1, PAWR, PRKAR1A, PTPN6, XCL1, SFTPD, SHH, SOX11, SPN, TNFAIP3, TNFSF4, TYRO3, SCGB1A1, PDE5A, PGLYRP1, TNFSF18, SOCS6, GLMN, VSIG4 |
1914 | GO:0031400 | 0.00 | 2.08 | 53.83 | 77 | 130 | negative regulation of protein modification process | ATM, BUB1, BUB1B, TSPO, CDC20, CDC27, CDK5, CENPF, CRY1, CRY2, DLG2, DLG3, FYN, HPN, DNAJB2, LIMK1, MAD2L1, PRKCE, PRKCG, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS3, RPS27A, SNTA1, SOX4, UBB, UBE2D1, USP4, WNT1, ZNF207, AKAP1, CDC23, URI1, CDC16, ZW10, BUB3, PSMF1, TMEM59, BAG5, BAG4, SFI1, PPP1R26, PSMD6, FRY, FARP1, PSME3, HMG20B, ANAPC10, PIAS3, CD2BP2, MAD2L2, CRTAP, GLMN |
1915 | GO:0010628 | 0.00 | 2.08 | 58.90 | 85 | 147 | positive regulation of gene expression | ACTA2, ADAR, ALOX12, AVP, AVPR2, PRDM1, C1QBP, C3, CCNB1, CD44, CDC42, CDH3, CDK4, CDK6, CIRBP, CNTF, CRP, CSF2, CTGF, DAZ1, DNMT1, DNMT3B, EEF2, EIF5A, ELAVL1, ERN1, F12, FBLN1, FGF8, FGF9, FGFR4, FOXD1, GAS6, HMX2, HOXD3, HSPA8, TNC, IL18, ITGA2, ITGA3, KLKB1, CD46, NTRK2, NTRK3, P2RX7, SERPINB9, PIK3CB, PRKAA1, MAPK8, DNAJC3, PTAFR, PTGER4, RAB27A, RBM3, RDX, RPS4X, RPS6KA2, RPS6KB2, SFRP4, TRA2B, SLC6A4, SNRNP70, SRPK2, STAR, TARBP2, CNTN2, CLEC3B, KDM6A, EZR, VIM, ZFP36, NR0B2, ALDH1A2, EIF2B5, QKI, RIMS2, SF3B4, RAMP2, PIAS3, OLFM1, AGR2, KHDRBS1, EDAR, ERP29, SNF8 |
1916 | GO:0002697 | 0.00 | 2.08 | 46.82 | 67 | 113 | regulation of immune effector process | AP2A1, AP2B1, ANXA5, BIRC3, ARF1, CA7, CD4, CD80, CD86, CD36, CD37, CD74, AP2M1, AP1S1, AP2S1, COX8A, CPA3, CLDN7, EIF2S1, STOM, FCGR3B, FGF7, FYN, SLC37A4, FFAR3, HCK, KCNQ1, MDH1, NTHL1, PDK4, PGC, SERPINB10, KLK7, RAC1, RARA, SCN1A, SNRPD1, STAT2, TNFAIP3, TNFRSF4, ZNF189, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, SEMA7A, RIPK2, AP1S2, AP1M1, BCL10, HIST1H3F, CHST3, ATG5, NUP93, PUM1, PHYHIP, IST1, ELMO1, TRIL, FGFBP1, AP1M2, SPON2, CREB3, CSPG5, TRAF3IP2 |
1917 | GO:0009132 | 0.00 | 2.08 | 25.87 | 37 | 62 | nucleoside diphosphate metabolic process | AK2, AK4, ALDOB, ALDOC, ARNT, BAD, BPGM, ENTPD2, DLG1, DLG2, DLG3, DTYMK, ENO2, GAPDH, GPD1, GUK1, HIF1A, HK2, IGF1, INS, LDHA, OGDH, P2RX7, PFKFB2, PFKFB4, PGAM2, PGK1, PGK2, PGM1, PPP2R5D, PRKAA1, RRM2, STAT3, OGT, ENTPD4, HDAC4, ECD |
1918 | GO:0051983 | 0.00 | 2.08 | 25.87 | 37 | 62 | regulation of chromosome segregation | APC, ATM, ATRX, BUB1, BUB1B, CCNB1, CDC6, CDC20, CDC27, CDC42, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, ECT2, MAD2L1, RB1, SFPQ, UBE2D1, ZNF207, CUL3, TNKS, BECN1, CDC23, CDC16, ZW10, BUB3, AURKB, PUM1, DLGAP5, ANAPC10, MAD2L2, CTCF, PTTG2, UBE2C, CIT |
1919 | GO:0043123 | 0.00 | 2.07 | 37.11 | 53 | 89 | positive regulation of I-kappaB kinase/NF-kappaB signaling | ABL2, BIRC3, BST2, CASP8, CASP10, CD36, CD40, CHUK, CTH, ECM1, ECT2, LPAR1, F2R, F2RL1, FLNA, FYN, IL1A, IRAK1, LTF, PARK2, PPM1A, PPP5C, PRKCB, PRKCE, PRKD1, RPS27A, S100A4, S100A12, S100A13, S100B, CCL21, SLC20A1, TNFRSF1A, TRAF2, UBB, UBE2V1, TRIM25, IKBKG, TNFSF11, TRADD, RIPK1, TNFSF10, RIPK2, TNFRSF10B, CFLAR, BCL10, VAPA, LITAF, TRIM22, TRIM38, TRAF3IP2, MALT1, PIM2 |
1920 | GO:0006109 | 0.01 | 2.07 | 17.48 | 25 | 42 | regulation of carbohydrate metabolic process | ARNT, BAD, BPGM, GOLGA2, GPD1, GPLD1, HIF1A, FOXA2, IGFBP3, IGFBP5, P2RX7, PARK2, PDK4, PFKFB2, PGAM2, PRKAA1, PRKCE, STAT3, RGN, TMEM59, HDAC4, NR1H4, ARFGEF1, DUSP12, ECD |
1921 | GO:0043901 | 0.00 | 2.07 | 37.14 | 53 | 89 | negative regulation of multi-organism process | ADA, ADAR, APCS, ARHGDIB, PRDM1, BST2, C1QBP, CD36, CTSG, FBLN1, FCN1, IFI16, IFIT1, IFNA2, IFNG, IGF1, IL2RA, IL10, ISG20, ITGAV, JUN, LTF, OAS1, OAS3, OVGP1, PARK2, PPM1B, EIF2AK2, PROX1, REST, SEC14L1, SLPI, SP100, SRPK2, TARBP2, TNFAIP3, TRIM25, ZP2, ZP3, TPST2, FCN3, OASL, VAPB, VAPA, TRIM28, TRIB1, TNIP1, IFITM3, TRIM38, PRDX4, IFITM2, SPINK5, PTGDR2 |
1922 | GO:0001837 | 0.01 | 2.07 | 21.70 | 31 | 52 | epithelial to mesenchymal transition | COL1A1, DAB2, EFNA1, EPHA3, ERG, FGF8, FLNA, HAS2, HGF, HIF1A, FOXA2, HPN, RBPJ, SMAD3, SMAD7, S100A4, SERPINB3, SDCBP, SNAI2, SNAI1, SOX9, TWIST1, WNT2, WNT11, EOMES, ADAM15, CUL7, TRIM28, OLFM1, MAD2L2, STRAP |
1923 | GO:0034763 | 0.01 | 2.07 | 19.61 | 28 | 47 | negative regulation of transmembrane transport | AKT2, ATP1A2, CALM3, CASQ2, CAV3, GRK6, GSTM2, KCNE1, KCNQ1, NTSR1, OAZ1, OAZ2, PAWR, PIK3C2A, PLN, PRKCE, SEMG1, SLN, SPINK1, TWIST1, SUMO1, SLC30A1, SLC9A3R1, GSTO1, OXSR1, KCNE2, KCNE3, TRDN |
1924 | GO:0007155 | 0.00 | 2.06 | 169.85 | 241 | 418 | cell adhesion | ACHE, ACTB, ACTG1, ACTN1, AMBN, AMBP, APLP1, APOA4, ARF6, RND3, ARHGAP5, RHOH, ASTN1, ATP4B, AXL, AZGP1, BAX, BCL3, BGLAP, BMX, DST, ZFP36L2, BYSL, CASP8, RUNX2, CCND3, CD7, CD8A, CD9, TNFSF8, SIGLEC6, SCARB1, SCARB2, ENTPD1, CD58, CD72, ADGRE5, CD151, CDH3, CDH6, CDH7, CDH8, CDH9, CDH10, CDH12, CDH15, CDH17, CDK5, CCR1, CCR3, CCR8, COL3A1, COL4A3, COL4A6, COL5A1, COL6A2, COL6A3, COL12A1, COL17A1, COL19A1, COMP, CLDN3, VCAN, CSRP1, CTGF, CTNNA1, CTNNA2, CTNND1, CTNND2, CX3CR1, CXADR, DSC2, DSC3, DSP, EDA, ADGRE1, CTTN, EPHA4, EPHB1, F2RL1, FAP, FCER1G, FLT3, FPR2, GAS6, B4GALT1, GNAS, GP1BA, RAPGEF1, GRID2, HAS1, HAS3, HCK, HOXD3, HSPB1, ICAM2, ICAM4, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, INS, INPPL1, ITGA1, ITGA7, ITGA9, ITGAD, ITGAE, ITGAM, ITGAX, ITGB4, ITGB5, JUP, KIT, LPP, BCAM, SMAD6, MFGE8, KITLG, CD200, NRCAM, DDR2, OMD, OLR1, OPCML, CLDN11, P2RX7, CNTN3, REG3A, PAX1, PCDHGC3, PCDH7, PCDH8, PCDH9, PGM5, RELN, PSMB10, PTK7, PTPRD, PTPRM, PVR, RAB1A, RAB27A, RAG2, RAP2B, PRPH2, RELB, RPL22, RS1, S100A8, S100A9, SATB1, SELE, SELL, SELPLG, SHC1, SLAMF1, SLC11A1, SIGLEC1, SOX4, SP3, SPAM1, SPG7, STK10, STK11, STXBP1, STXBP3, CNTN2, ICAM5, TNFAIP6, TPBG, CRISP2, TRIP6, TRO, TNFRSF4, TYRO3, COL14A1, VCL, EZR, ZAN, FZD5, MADCAM1, SYMPK, EOMES, FZD8, SRPX, SORBS2, CNTNAP1, ITGA8, AOC3, DCHS1, STX11, CTNNAL1, SIGLEC5, IL18R1, NRP2, CD84, WISP3, WISP1, SGCE, PSTPIP1, CLDN12, CLDN8, CLDN6, FIBP, IL32, TAOK2, SLIT2, ITGBL1, NRXN3, NRXN1, NRXN2, THEMIS2, BCAR1, SDC3, FARP2, BCL2L11, GNE, TROAP, PTPRU, CHST4, SORBS3, CD96, EFS, TNIP1, SPON2, SPON1, GPNMB, FBLN5, BATF, SORBS1, PDPN, CGREF1, CLDN16, CHL1, FERMT2, ADAMTS13, EMILIN1, IL1RAPL1, BVES |
1925 | GO:1904894 | 0.01 | 2.06 | 17.53 | 25 | 42 | positive regulation of STAT cascade | CD40, CNTF, CSF2, CTF1, F2R, FGFR3, FLT3, FYN, HCLS1, HPX, HES1, IFNA2, IFNG, IGF1, IL10, IL13, IL18, ISL1, KIT, PTGER4, TNFRSF1A, TNFRSF18, TNFSF18, CRLF1, IL24 |
1926 | GO:0016485 | 0.00 | 2.06 | 47.74 | 68 | 115 | protein processing | A2M, ADAM10, AEBP1, ANPEP, BIRC3, XIAP, BIRC5, BGLAP, C1QBP, SERPING1, C3, C5, C8B, CD59, CGA, CLN5, CPA3, CPD, CR1, CTSG, CTSS, CTSZ, CD55, ACE, ENPEP, F7, F10, GAS1, GAS6, GZMH, IDE, IHH, CD46, P2RX7, PCSK6, PCSK1, PCSK5, CFP, PHB, PIK3C3, SRGN, PRKACB, PROC, PROS1, PTCH1, PTHLH, RFX4, RPS6KA2, RPS27A, SHH, CNTN2, TSG101, TSHB, UBB, UQCRC1, UQCRC2, VTN, IFT88, PROZ, RHBDL1, PCSK7, ADAMTS3, ADAMTS2, TMEM59, SPCS2, ATP6AP2, CORIN, ADAMTS13 |
1927 | GO:0030308 | 0.00 | 2.06 | 40.06 | 57 | 96 | negative regulation of cell growth | ACVR1B, ACVRL1, AGTR2, APBB1, ARHGAP4, BCL2, BMPR2, BST2, BTG1, CAV3, CDA, CDK5, CDKN1A, CDKN2A, CDKN2C, CDKN2D, CRYAB, CYP27B1, DCC, DDX3X, EPHA7, GDF9, HRG, ING1, SMAD3, ENPP1, PHB, PPP2R1A, PPT1, PTPRJ, RNF6, SEMA3F, SIPA1, SLIT3, SMARCA2, SMARCA4, STK11, TNR, TRO, WNT11, SEMA3B, TNK1, ADAM15, CTDP1, SLIT2, EI24, AATK, SEMA3E, SERTAD2, SEMA3A, SEMA6C, SEMA6B, SEMA4F, SEMA4B, GAS2L1, CGREF1, CCDC85B |
1928 | GO:0009267 | 0.00 | 2.06 | 28.80 | 41 | 69 | cellular response to starvation | ALB, ASNS, ATF3, ATF4, BCL2, BMPR2, CDKN1A, COMT, CTSV, DSC2, EIF2S1, GAS6, GLUL, HSPA8, IFI16, JUN, PCK1, PDK4, PIK3C3, PRKAA1, EIF2AK2, RHAG, RHCE, RHD, SRD5A1, SREBF1, KLF10, UPP1, WNT2B, WRN, PPM1D, AKR1C3, BECN1, EIF2AK3, PICK1, ATG5, CARTPT, ATG7, GAS2L1, RRAGA, SLC38A3 |
1929 | GO:0018107 | 0.02 | 2.05 | 15.44 | 22 | 37 | peptidyl-threonine phosphorylation | ACVR1, ACVR1B, ADRBK1, BCL2, CALM3, CDK5, CHI3L1, DYRK1A, GCG, UBE2K, SMAD7, PDPK1, PRKCA, PRKCB, MAPK8, VRK1, OGT, TNKS, RIPK2, S1PR2, VPRBP, OXSR1 |
1930 | GO:2000816 | 0.02 | 2.05 | 15.44 | 22 | 37 | negative regulation of mitotic sister chromatid separation | APC, ATM, BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DUSP1, MAD2L1, UBE2D1, ZNF207, CDC23, CDC16, ZW10, BUB3, ANAPC10, MAD2L2, PTTG2, UBE2C |
1931 | GO:0033059 | 0.03 | 2.05 | 13.35 | 19 | 32 | cellular pigmentation | AP1G1, SHROOM2, BBS2, BBS4, BCL2, CD63, CDH3, BLOC1S1, RAB1A, RAB27A, RAB27B, TYRP1, AP3B1, RAB11A, AP1M1, AP3D1, RAB11B, ZEB2, RAB32 |
1932 | GO:0014065 | 0.05 | 2.05 | 11.23 | 16 | 27 | phosphatidylinositol 3-kinase signaling | C1QBP, CRYBA1, ERBB2, GATA3, IGF1R, PIK3C2A, PIK3C2B, PIK3CB, PIK3CG, PTPN13, TSC2, TWIST1, TYRO3, KLF4, SLC9A3R1, STAMBP |
1933 | GO:0051438 | 0.00 | 2.04 | 42.98 | 61 | 103 | regulation of ubiquitin-protein transferase activity | APC, ATM, BMI1, BUB1, BUB1B, CCNB1, CDC20, CDC27, CDKN2A, CENPF, DUSP1, LIMK1, MAD2L1, SMAD7, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SKP1, UBB, UBE2D1, UBE2L3, ZNF207, CUL1, CDC14B, CDC23, CDC16, ZW10, BUB3, PSMF1, BAG5, PSMD6, FEM1B, PSME3, ANAPC10, ZER1, MAD2L2, UBE2C |
1934 | GO:0051783 | 0.00 | 2.04 | 42.98 | 61 | 103 | regulation of nuclear division | APC, BIRC5, ATM, ATRX, BMP4, BUB1, BUB1B, CAV2, CCNB1, CD28, CDC6, CDC20, CDC25C, CDC27, CDC42, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, EDN3, EREG, FGF8, FGFR3, GPR3, IGF1, IGF1R, IGF2, IL1A, IL1B, INS, MAD2L1, CHMP1A, PDE3A, PRKAR1A, RAD1, RB1, RPS6KA2, AURKA, UBE2D1, ZNF207, CUL3, CDC14A, CDK13, TNKS, BECN1, CDC23, CDC16, ZW10, BUB3, MAD2L1BP, KNTC1, DLGAP5, CUL7, TOM1L1, ANAPC10, MAD2L2, PTTG2, UBE2C, CIT, PHB2 |
1935 | GO:0009628 | 0.00 | 2.04 | 34.79 | 50 | 87 | response to abiotic stimulus | ATP2B1, BAG1, CAMK2A, CAMK2G, CD9, CDH8, CETN1, DHX9, EIF2B1, FGF1, GK, HMGCS2, HSBP1, HSPA6, HSPA8, HSP90AA1, IL1A, IMPDH1, ATXN3, MKI67, NUP88, NUP98, DNAJC3, RANBP2, RBM3, RPA3, SOD1, STAC, DNAJC7, NUP214, AAAS, SLC14A2, SNN, EIF2B4, EIF2B3, EIF2B2, EIF2B5, EIF2AK3, BAG5, BAG4, NUP155, ZNF516, NUP93, HDAC6, PDCD6, NUP50, ARPP21, DNAJB4, NUPL2, PSIP1 |
1936 | GO:0031325 | 0.00 | 2.04 | 205.34 | 291 | 521 | positive regulation of cellular metabolic process | ABAT, ABL2, ACLY, ACVR2B, ADCY1, ADCY3, ADCY6, ADCY9, ADORA1, ADRA2C, ALOX12, ANG, ANGPT1, ANXA1, ANXA2, BIRC3, XIAP, ASIP, ATP6AP1, CCND1, BCL2, BID, BMI1, BMP1, BMP8B, BOK, C1QBP, C3, C5, CAMK2G, CASP8, CASP9, CAV2, CCK, CCND3, CD4, CD14, TNFRSF8, SCARB1, CD44, CD63, CD74, CDC6, CDH3, CDK4, CDK5, CENPE, CHI3L1, CIRBP, CCR1, CNTF, COL4A3, COMT, CR1, CSF2RB, CSPG4, CTF1, CTGF, DAZ1, ACE, DLG1, DNMT1, DNMT3B, HBEGF, DUSP5, DUSP7, DUSP9, DYRK1A, GPR183, ECT2, LPAR1, EDN3, EDNRB, EEF1A2, EEF2, EFNA1, EFNA5, EIF5A, ELAVL1, EMP2, EPHA4, EPHA7, EPHA8, F3, F12, ACSL1, ACSL3, FBLN1, FCER1A, FGA, FGF3, FGF6, FGF8, FGF9, FGFR3, FGG, FGR, FLT1, FLT3, FLT3LG, FLT4, FNTA, FPR1, FYN, GAS6, GDF9, GHSR, GOLGA2, RAPGEF1, GRIN2A, GRM1, HIST1H1B, HIP1, UBE2K, HMGCR, HPRT1, HPX, PRMT1, HSPB1, HTR2C, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGFBP3, IL2RA, IL2RB, IL2RG, IL13, IL18, INHA, ITGA1, ITGA2, ITGA5, ITGB1, JARID2, KISS1, KLKB1, MARK3, MAP3K5, MAP3K11, SLC11A2, NRAS, NTRK3, TNFRSF11B, PEBP1, PAWR, PCOLCE, PDE6G, PDE6H, ENPP2, PDPK1, PFN2, PIM1, PIK3CG, PPP1R7, PPP5C, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, DNAJC3, PTPRA, PTPRZ1, RAB1A, RAP1A, RAP2A, RAP2B, RASA2, RBM3, RPS4X, RPS6KB2, RYK, SERPINB3, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SDCBP, SELE, SEMG1, SFRP4, ITSN1, STIL, SKP2, SLAMF1, SNAI2, SMPD1, SMPD2, SOS1, SPN, SPTA1, SPTB, STK10, XCL2, SYK, TARBP2, CNTN2, NR2F1, CLEC3B, TPD52L1, TNFRSF4, TYRP1, UBE2L3, VEGFB, VEGFC, VTN, ZNF16, AIMP2, CDK2AP1, SYMPK, BCAR3, NSMAF, SEMA7A, CDC14B, MADD, PDE5A, PEA15, EED, CRADD, TNFSF10, TNFRSF6B, TNFRSF18, TNFRSF10B, TNFRSF10A, IQGAP1, EIF2B5, CDK5R2, LATS1, AIFM1, BMP15, CRLF1, GPR55, S1PR2, TAOK2, PICK1, AKAP6, GDF15, BAG4, CARTPT, TRAF4, RAPGEF2, SLK, RASSF2, IST1, RB1CC1, OXSR1, TNFSF15, RBX1, CASP8AP2, ABI1, HDAC6, PDCD6, BCL2L10, BCL2L11, TOM1L1, AKAP9, EBI3, RASA4, SORBS3, TNK2, RAMP3, ABCA7, PRG3, PIAS3, VAV3, STK25, ARL6IP5, ARFGEF1, KHDRBS1, NRG3, FRS3, JTB, COPS8, ERP29, IL24, RBPMS, ADRM1, GLMN, BVES, MAP4K5, RASSF1, FZD10 |
1937 | GO:0006006 | 0.02 | 2.04 | 16.17 | 23 | 39 | glucose metabolic process | BRS3, CACNA1A, CALM3, SLC37A4, GAA, GYS2, ONECUT1, INPPL1, KCNJ11, OAS1, PHKA2, PHKG1, PPP1R3C, PRKAA1, PYGL, PYGM, RPS27A, SORD, UBB, UGP2, USF1, EPM2A, AKR1A1 |
1938 | GO:0072331 | 0.00 | 2.03 | 45.91 | 65 | 110 | signal transduction by p53 class mediator | ATM, ATR, ATRX, BAX, BCL3, BDKRB2, BOK, BRCA1, BRCA2, CD44, CD74, CDKN1A, CDKN2A, DDX5, DYRK1A, E2F2, EP300, HIC1, IFI16, ING2, PARK2, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SNAI2, SNAI1, SOX4, SP100, STK11, TP73, TWIST1, UBB, DYRK2, TP63, CRADD, TRIM24, PSMF1, PSMD6, PSME3, BATF, HEXIM1 |
1939 | GO:0051348 | 0.00 | 2.03 | 89.31 | 126 | 214 | negative regulation of transferase activity | ADAR, ADARB1, APC, ATM, BMP4, BUB1, BUB1B, CAV3, CCNB1, CDC20, CDC27, CDKN1A, CDKN2A, CDKN2C, CDKN2D, CENPF, CHAD, CISH, DCN, GADD45A, DUSP1, DUSP4, DUSP5, DUSP7, DUSP9, EIF4A2, EPHA1, GNAQ, SFN, GP1BA, GPS2, HHEX, HMGCR, FOXA2, HSPB1, IGF1R, IL1B, ILK, LIMK1, MAD2L1, SMAD7, MEN1, PARK2, PCP4, PDPK1, PPP1R1A, PPP2R1A, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, DNAJC3, PRPSAP1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN1, PTPN6, PTPRJ, RANBP2, RB1, RGS2, RPS27A, SERPINB3, SMPD1, SORL1, TAF7, TARBP2, NR2F2, TNFAIP3, TP73, TSC2, UBB, UBE2D1, YWHAG, ZNF207, CUL3, CDC23, KAT2B, CDC16, SOCS3, RGN, LATS1, ZW10, BUB3, ITGB1BP1, SOCS6, PSMF1, BAG5, GMFG, RUBCN, PSMD6, PSME3, TRIB1, ANAPC10, MAD2L2, HEXIM1, RGS14, CERS1, PRDX3, UBE2C, STK38 |
1940 | GO:0009150 | 0.04 | 2.03 | 11.92 | 17 | 29 | purine ribonucleotide metabolic process | ATP2B2, CACNB4, HMGCR, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE8A, PDE1B, PF4, VEGFA, PDE5A, RAPGEF3, PDE10A |
1941 | GO:0045185 | 0.01 | 2.03 | 20.45 | 29 | 49 | maintenance of protein location | ARL2, BBS4, BCL3, TSPO, CD4, DBN1, FBN1, FLNA, NR5A1, HK2, IL10, JUP, LTBP1, TONSL, SRGN, SORL1, SPAG4, TRIP6, EZR, TNFSF14, LATS1, CER1, SUPT7L, TACC3, CREB3, KDELR1, OS9, KDELR3, TWF2 |
1942 | GO:0031032 | 0.00 | 2.03 | 27.51 | 39 | 66 | actomyosin structure organization | APOA1, ARHGAP6, BBS4, CNN1, CNN3, CTGF, S1PR1, LPAR1, EPHA1, ITGB5, LIMK1, TACSTD2, SMAD3, PFN1, PFN2, PRKCQ, PTGER4, RAC1, S100A10, SDC4, SLC9A1, TAC1, TMOD1, TSC1, WNT11, ALMS1, ARHGEF5, CSRP3, CUL3, CDC42BPA, CFLAR, ITGB1BP1, BAG4, CDC42BPB, WASF2, SORBS3, RAPGEF3, SORBS1, SYNPO |
1943 | GO:0006979 | 0.00 | 2.03 | 38.04 | 54 | 92 | response to oxidative stress | ALAD, ARNT, ARNTL, ATF4, BTG1, CD38, CHUK, DHCR24, ERCC1, ERCC3, ETFDH, ETV5, FGF8, FUT8, GJB2, GSS, HSPB1, IDH1, INS, KRT1, MGMT, NUDT1, SLC11A2, OGG1, PARK2, PENK, PRKD1, PSMB5, PTGS1, SEPP1, SFPQ, STAU1, TAT, TRPM2, UCN, WRN, XPA, PXDN, EPX, ATRN, PRKRA, KAT2B, VNN1, PDLIM1, BAG5, OXSR1, SLC23A2, SGK2, DHRS2, COQ7, RCAN2, ARL6IP5, RGS14, PSIP1 |
1944 | GO:0043648 | 0.01 | 2.03 | 18.33 | 26 | 44 | dicarboxylic acid metabolic process | ADSS, APC, ASPA, ASS1, DHFR, DLD, GLS, GLUD1, GLUD2, GLUL, HAL, IDH1, OAT, OGDH, ALDH18A1, SHMT1, SHMT2, STAR, TAT, DDO, ALDH4A1, KYNU, GRHPR, NR1H4, ACOT8, ALDH1L1 |
1945 | GO:0008202 | 0.01 | 2.03 | 19.00 | 27 | 46 | steroid metabolic process | ABCA1, ACADL, ACADVL, APOF, APLP2, CAT, CETP, COMT, CYP2A6, CYP3A5, FECH, G6PC, FOXA2, LCAT, LIPA, LIPE, SORL1, SULT1E1, SULT1A1, SULT1A3, SULT2B1, TNFSF4, CUBN, NR0B2, SOAT2, NR1I2, DHRS4 |
1946 | GO:0050790 | 0.00 | 2.03 | 146.94 | 208 | 367 | regulation of catalytic activity | ACVR2B, ADORA1, ADORA2A, ADRA2C, ALK, ANGPT1, ARF1, AVPR2, CCND1, BCL2, BMI1, CALCR, CAMK2A, CAMK2G, KRIT1, CCNC, CCND3, CCNE1, CCNH, CCNT1, CCNT2, CD4, CD74, CDC6, CDC25C, CDC42, CDK4, CDK5, CENPE, CHI3L1, CKS1B, CLU, CLPS, CSF2, CSF2RB, CSPG4, ACE, DLG1, RCAN1, HBEGF, EDN3, EEF1A2, EFNA1, EMP2, EPHA8, EREG, ERCC6, ACSL1, FCER1A, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR4, FGR, FLT3, FPR1, FSHR, FYN, GCG, GHRHR, GLP1R, GNAL, GRB2, GRIN2A, GRM1, CXCL1, GTF2F1, GUCA1A, GUCA1B, GUCA2A, GUCA2B, NRG1, HSP90AB1, IGF2, IGFBP3, IL2RA, IL2RB, IL2RG, IRAK1, IRAK2, MARK3, KITLG, MGST2, MAP3K11, PPP1R12B, SEPT2, NRAS, DDR2, NVL, P2RX7, P2RY11, PFKFB2, PIK3CB, PIM1, PIK3CG, FXYD3, PPP1R3C, PPP1R7, PPP5C, PRKAA1, PRKAB2, PRKCQ, MAPK3, PROX1, RELN, PTPRA, RAC1, RAC2, RAP2B, RBL1, RBL2, RCVRN, RFC1, RPS2, S100A12, SDC4, SFTPB, SGK1, SHC1, STIL, SKP1, SLAMF1, SLC11A1, SPTA1, SPTB, STK10, STK11, SYK, TPD52L1, TSG101, TNFRSF4, UBE2L3, UCN, UVRAG, VIP, VIPR2, WFS1, XRCC4, ZNF16, ZP3, LRP8, FZD5, SHOC2, FZD4, FZD8, NSMAF, CUL1, OGT, PIK3R3, IKBKG, IKBKAP, CAMK1, MAPKAPK5, CDC14B, PRKRA, TNFSF11, PDE5A, DYNLL1, TNKS, BECN1, PEA15, ADAM9, RIPK2, CDK5R2, DIRAS3, CCNE2, AURKB, S1PR2, GTF3C4, TAOK2, SLC9A3R1, BAG3, CARTPT, TRAF4, GUCA1C, SLK, RASSF2, ZEB2, EPM2AIP1, OXSR1, RBX1, ABI1, TOM1L1, UBA2, RAD50, FEM1B, AKAP9, RCAN2, ZER1, CAP2, CAP1, STK25, CCT4, CCT2, NRG3, FRS3, MALT1, JTB, COPS8, DBF4, ERP29, RCAN3, CDC37, MAP4K5, DUSP12 |
1947 | GO:0001824 | 0.01 | 2.02 | 18.36 | 26 | 44 | blastocyst development | ADA, BRCA2, BYSL, CDX2, DAD1, DMBT1, ELF3, ETV2, GRN, IGF1, JUNB, CNOT2, PSMC3, PSMC4, RAD51B, RBBP8, SP1, SP3, SRF, ZP3, EOMES, CUL3, LATS1, HAND1, GINS1, SETDB1 |
1948 | GO:1900034 | 0.01 | 2.02 | 18.36 | 26 | 44 | regulation of cellular response to heat | ATM, ATR, BAG1, CAMK2A, CAMK2G, CRYAB, EP300, HSBP1, HSPA8, HSP90AA1, HSP90AB1, NUP88, NUP98, MAPK3, RANBP2, RPA3, DNAJC7, NUP214, AAAS, BAG5, BAG4, BAG3, NUP155, NUP93, NUP50, NUPL2 |
1949 | GO:2000021 | 0.03 | 2.02 | 14.09 | 20 | 34 | regulation of ion homeostasis | ADCYAP1R1, ADORA1, AGTR2, ANPEP, AVPR2, BMP4, CD4, COMT, EDNRB, KNG1, OXT, P2RX3, P2RX4, PTGER4, TAC1, TRPC3, SLC30A1, SLC30A2, AP3D1, CORIN |
1950 | GO:0009582 | 0.03 | 2.02 | 14.11 | 20 | 34 | detection of abiotic stimulus | ADORA1, ATP2B2, CAV3, COL11A1, EPHB1, FYN, HPN, IGF1, ITGA2, JUP, KCNA1, KIT, NTRK1, NTSR1, PAWR, SLC12A2, SOX2, TAC1, TRPV1, CSRP3 |
1951 | GO:0072330 | 0.00 | 2.02 | 42.48 | 60 | 102 | monocarboxylic acid biosynthetic process | ABAT, ACADL, ACADM, ACADVL, ACLY, AGXT, ALDH1A3, ALDH9A1, ALOX12, ALOX15B, ANXA1, APOA1, APOA4, APOC2, AVP, BRCA1, CD74, VCAN, CSPG4, DCN, EDN2, ACSL3, FCER1A, GAD1, GGT7, HPGD, IDO1, INSIG1, LDHC, FADS3, LTA4H, MGST2, PDK4, PRKAA1, PRKAB2, PTGIS, PTGS1, ABCD3, RBP1, RNPEP, ACSM3, SHMT1, ELOVL4, STK11, SYK, NR1H2, BBOX1, AKR1C3, ALDH1A2, RGN, FADS2, QKI, DHRS9, PRG3, ERLIN1, CSPG5, FAXDC2, SDS, ERLIN2, ACOT7 |
1952 | GO:0009119 | 0.00 | 2.02 | 47.47 | 67 | 114 | ribonucleoside metabolic process | ALDOB, ALDOC, AMPD2, ARNT, ATP1A2, ATP6V1A, ATP6V1B1, ATP6V1B2, BAD, BPGM, TSPO, CDA, COX4I1, COX8A, COX15, CTNS, DLD, DLG1, DLG2, DLG3, DNMT1, DNMT3A, DNMT3B, ENO2, GAMT, GAPDH, GNAI3, GPD1, HIF1A, HK2, HMGCR, HSPA8, IGF1, INS, LDHA, OGDH, P2RX7, ENPP1, PFKFB2, PFKFB4, PGAM2, PGK1, PGK2, PGM1, PPP2R5D, PRKAA1, PTGDR, SDHC, SNCA, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, SULT2A1, TAZ, UQCRB, UQCRC1, UQCRC2, UQCRH, OGT, COX5A, ENTPD4, HDAC4, COQ7, AHCYL1, ECD |
1953 | GO:2001235 | 0.03 | 2.02 | 14.13 | 20 | 34 | positive regulation of apoptotic signaling pathway | BIK, BNIP3, CD14, SFN, SMAD3, PPP3R1, MAPK8, TPD52L1, YWHAG, YWHAH, YWHAZ, TP63, DYNLL1, TRADD, CRADD, HRK, TNFRSF10B, TNFRSF10A, CFLAR, SIVA1 |
1954 | GO:0032846 | 0.00 | 2.01 | 26.17 | 37 | 63 | positive regulation of homeostatic process | ABAT, ACOX1, ACVR1B, ACVR2A, ANXA1, ARNT, ATM, ATP6AP1, ATR, ATRX, AVP, CA2, CA7, CNR1, ERCC1, ETS1, PRMT1, IL1B, PRKCQ, MAPK3, SLC22A5, SMARCA4, SYK, TAL1, CCT3, ZNF16, SLC30A2, MAPKAPK5, TNFSF11, TNKS, AURKB, RAD50, CCT7, CCT4, CCT2, CCT8, SEC24A |
1955 | GO:0050776 | 0.00 | 2.01 | 26.67 | 38 | 66 | regulation of immune response | CD8A, CD37, CDH1, COL1A1, COL2A1, COL17A1, CXADR, FCGR2B, ICAM1, ICAM4, IFNA5, IFNA13, IFNA17, IFNA21, IFNGR1, ITGA4, ITGAL, ITGB1, KLRB1, KLRD1, SMAD3, CD200, PTPN1, SELL, SFTPD, STAT2, TYK2, TYROBP, SUMO1, MADCAM1, SOCS3, CLEC2B, CD96, CXCL13, CD300C, CD160, CDC37, USP18 |
1956 | GO:0014031 | 0.01 | 2.01 | 21.23 | 30 | 51 | mesenchymal cell development | ACVR1, BCL2, BMPR1A, EDN3, EDNRA, EDNRB, GDNF, NRG1, HES1, ISL1, LAMA5, KITLG, NRTN, MAPK3, SEMA3F, SHH, SOX10, SOX11, SEMA3B, SEMA7A, ALDH1A2, PHOX2B, HAND2, SEMA3E, ZEB2, SEMA3A, SEMA6C, SEMA6B, SEMA4F, SEMA4B |
1957 | GO:0006818 | 0.00 | 2.01 | 42.57 | 60 | 102 | hydrogen transport | ACTN4, ATP1A2, ATP12A, ATP4A, ATP4B, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, ATP5O, COX4I1, COX5B, COX6A1, COX6A2, COX6B1, COX7A1, COX7B, COX7C, COX8A, COX15, IL13, SLC11A2, SLC9A1, SLC9A3, SLC9A5, SLC15A1, SLC15A2, SURF1, TWIST1, UCP1, UQCRC1, UQCRFS1, UQCRH, ATP6V0E1, SLC25A14, ATP6V0D1, COX7A2L, ATP6V1F, SLC9A3R1, COX5A, ATP6V1G1, ATP5J2, SLC23A2, RAPGEF3, ATP5H, SLC9A6, SLC35A1, ATP5L, UQCR11 |
1958 | GO:0031334 | 0.00 | 2.01 | 40.42 | 57 | 97 | positive regulation of protein complex assembly | APC, ARF1, ARF6, ARL2, BAX, BID, BIK, CAV3, CCK, CD36, CDH17, CSF2, DLG1, CTTN, GRB2, HCK, ICAM1, IDE, PFN1, PFN2, PRKCE, MAPK8, RAC1, RGS2, RPS3, CLIP1, CCL21, CCL24, TAL1, SUMO1, VEGFA, VIL1, ARHGEF5, HRK, WASF1, PICK1, BAG4, GMFG, HDAC6, BCL2L11, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, ABI2, TUBGCP3, CDC42EP2, BAIAP2, UNC13B, ARPC1A, CXCL13, CDC42EP3, TPPP, CDC42EP1, CORO1A |
1959 | GO:0044262 | 0.00 | 2.00 | 46.12 | 65 | 111 | cellular carbohydrate metabolic process | BPGM, CALM3, CPS1, EXT1, EXT2, G6PC, GALK1, GALK2, GCGR, GK, GK2, GLB1, GOLGA2, GOT1, GPD2, GYS2, HAS1, HAS2, HAS3, HK2, FOXA2, IDH1, IGFBP3, IGFBP5, IMPA1, IMPA2, INPP1, KHK, PARK2, PCK1, PDK4, ENPP1, PFKFB4, PGAM2, PGD, PGM1, PHKA2, PHKG1, PPP1CA, PPP1R1A, PPP1R2, PPP1R3C, PYGL, PYGM, RANBP2, RPE, RPS27A, SLC5A3, SORD, STAT3, UBB, UGP2, EPM2A, OGT, SYNJ1, STBD1, TMEM59, NR1D1, PPIP5K1, HDAC4, XYLB, GNE, B3GNT3, ARFGEF1, ECD |
1960 | GO:0009611 | 0.00 | 2.00 | 39.33 | 56 | 98 | response to wounding | ACHE, AHSG, BIRC3, XIAP, DST, C5, C8B, CASP4, CASP5, CD6, CD28, CCR1, CNR1, CR1, CTGF, CTSS, CD55, EDNRA, EDNRB, FCER1A, GFAP, FFAR3, GRIN2A, HCK, IL1R1, IL18, IDO1, ITGB4, CD46, PAWR, PER1, CFP, PHB, PSMA6, S100A12, SCN3A, CCL24, XCL1, SRSF5, STAT5B, XCL2, TAC1, TNFSF4, SCGB1A1, WNT1, ZP3, SEMA7A, TNFSF11, VAMP8, IL1RL2, TNFSF18, IL1RL1, CLOCK, NR1D2, TNIP1, ABHD2 |
1961 | GO:0000079 | 0.03 | 2.00 | 14.17 | 20 | 34 | regulation of cyclin-dependent protein serine/threonine kinase activity | CCND1, CCNC, CCND3, CCNH, CCNT1, CCNT2, CDC6, CDC25C, CDKN2C, CDKN2D, CKS1B, GADD45A, SFN, PIM1, PROX1, STIL, CDK5R2, DIRAS3, CCNE2, CDC37 |
1962 | GO:0001523 | 0.01 | 2.00 | 21.28 | 30 | 51 | retinoid metabolic process | ABCA4, ADH5, ALDH1A1, ALDH1A3, APOA1, APOA4, APOC2, OPN1SW, AKR1C4, CLPS, GPC4, GPC5, OPN1MW, GPC3, GPC1, RBP1, RBP2, OPN1LW, RLBP1, SDC1, SDC2, SDC4, LRP8, AKR1C3, DGAT1, ALDH1A2, DHRS3, SDC3, GPC6, DHRS9 |
1963 | GO:0051651 | 0.01 | 2.00 | 21.28 | 30 | 51 | maintenance of location in cell | ALB, ARL2, ATP2A1, BBS4, BCL3, TSPO, CD4, DBN1, FLNA, NR5A1, GAA, HK2, IL10, JUP, TONSL, SRGN, SORL1, SPAG4, TRIP6, UVRAG, EZR, TNFSF14, LATS1, SUPT7L, TACC3, CREB3, KDELR1, OS9, KDELR3, TWF2 |
1964 | GO:0061572 | 0.00 | 2.00 | 33.39 | 47 | 80 | actin filament bundle organization | ABL2, ACTN4, ACTN1, ADD1, APOA1, ARHGAP6, BBS4, CDC42, CTGF, DPYSL3, S1PR1, LPAR1, EPHA1, EPS8, ITGB5, LIMK1, TACSTD2, SMAD3, MYO1B, PARK2, PAWR, PFN1, PFN2, PRKCQ, PTGER4, RAC1, RDX, S100A10, SDC4, SLC9A1, SRF, TAC1, TSC1, VIL1, EZR, WNT11, ALMS1, ARHGEF5, CUL3, ITGB1BP1, BAG4, WASF2, SORBS3, RAPGEF3, BAIAP2, SORBS1, SYNPO |
1965 | GO:0032637 | 0.03 | 2.00 | 14.19 | 20 | 34 | interleukin-8 production | ANXA1, ANXA4, BCL3, BPI, CD2, CD58, CHI3L1, CRP, F2R, F2RL1, FCN1, IL1B, IL10, SERPINE1, PTGER4, RAB1A, RIPK1, BCL10, KLF4, PRG3 |
1966 | GO:0042278 | 0.00 | 2.00 | 46.23 | 65 | 111 | purine nucleoside metabolic process | ALDOB, ALDOC, AMPD2, ARNT, ATP1A2, ATP6V1A, ATP6V1B1, ATP6V1B2, BAD, BPGM, TSPO, COX4I1, COX8A, COX15, CTNS, DLD, DLG1, DLG2, DLG3, DNMT1, DNMT3A, DNMT3B, ENO2, GAMT, GAPDH, GNAI3, GPD1, HIF1A, HK2, HMGCR, HSPA8, IGF1, INS, LDHA, OGDH, P2RX7, ENPP1, PFKFB2, PFKFB4, PGAM2, PGK1, PGK2, PGM1, PPP2R5D, PRKAA1, PTGDR, SDHC, SNCA, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, SULT2A1, TAZ, UQCRB, UQCRC1, UQCRC2, UQCRH, OGT, COX5A, HDAC4, COQ7, AHCYL1, ECD |
1967 | GO:0001841 | 0.00 | 2.00 | 26.29 | 37 | 63 | neural tube formation | BBS4, BMP4, CASP8, KAT2A, ARHGAP35, HIF1A, OPA1, PAX2, PFN1, PRKACB, PTCH1, PTK7, RALA, RARA, SALL1, SDC4, STIL, SOX4, SOX11, SPINT1, ST14, T, TSC1, TSC2, TULP3, TWIST1, KDM6A, ZIC2, FZD3, FZD6, BCL10, ZEB2, COQ7, SEC24B, DEAF1, SPINT2, GLMN |
1968 | GO:0046496 | 0.00 | 2.00 | 26.29 | 37 | 63 | nicotinamide nucleotide metabolic process | ALDOB, ALDOC, ARNT, BPGM, DLD, ENO2, GAPDH, GPD1, HIF1A, HK2, IDH1, IGF1, INS, LDHA, MDH1, MDH2, OGDH, P2RX7, PFKFB2, PFKFB4, PGAM2, PGD, PGK1, PGK2, PGM1, PPP2R5D, PRKAA1, PTGIS, RPE, STAT3, PDHX, OGT, KCNAB2, KYNU, TP53I3, HDAC4, ECD |
1969 | GO:1903510 | 0.01 | 2.00 | 24.15 | 34 | 58 | mucopolysaccharide metabolic process | ANGPT1, VCAN, CSPG4, DCN, GPC4, GPC5, GALNS, B4GALT1, GPC3, GLB1, GPC1, IDS, IDUA, LUM, CHST6, OMD, OGN, SDC1, SDC2, SDC4, B4GALT4, B4GALT3, B4GALT6, B4GALT5, CHST3, SDC3, SPOCK2, GPC6, B3GNT3, ST3GAL6, CSPG5, SLC35D2, KERA, B4GALT7 |
1970 | GO:0045637 | 0.05 | 1.99 | 12.06 | 17 | 29 | regulation of myeloid cell differentiation | CDK6, GABPA, ITPKB, MEIS1, STAT5B, HIST1H4I, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, RNF41, GAS2L1 |
1971 | GO:0006906 | 0.01 | 1.99 | 19.18 | 27 | 46 | vesicle fusion | CAV2, GNAI3, LRMP, RAB8A, RAB3A, SLAMF1, SNAP25, STXBP1, SYT4, UVRAG, RAB7A, DYSF, EEA1, USO1, VAMP8, STX16, STX11, STX10, SNAP23, SEC22C, SNAP29, GOSR1, SEC22B, STX6, VAV3, VAMP5, CORO1A |
1972 | GO:0045839 | 0.01 | 1.99 | 19.20 | 27 | 46 | negative regulation of mitotic nuclear division | APC, ATM, ATRX, BMP4, BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DUSP1, FGFR3, MAD2L1, UBE2D1, ZNF207, TNKS, CDC23, CDC16, ZW10, BUB3, TOM1L1, ANAPC10, MAD2L2, PTTG2, UBE2C |
1973 | GO:0098660 | 0.00 | 1.99 | 159.54 | 222 | 383 | inorganic ion transmembrane transport | ACTN4, ANXA5, SHROOM2, AQP1, ARF1, ATP1A2, ATP12A, ATP1B3, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP4A, ATP4B, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, ATP5O, ATP7B, BAX, HCN2, BMP4, CACNA1A, CACNA1B, CACNA1E, CACNA1F, CACNA1S, CACNA2D1, CACNB4, CACNG1, SLC25A20, CALM3, CASQ2, CAV3, CCR5, CNGA1, CNGA2, COX4I1, COX5B, COX6A1, COX6A2, COX6B1, COX7A1, COX7B, COX7C, COX8A, COX15, CPT1B, CPT2, CYBA, DIAPH1, DLG1, DNM2, DPP6, EDN3, EDNRA, STOM, F2R, GAS6, GPM6A, XCR1, GRIN2A, GSTM2, HPN, HRC, HTR2C, HTR3A, IL13, ITGAV, ITPR1, ITPR2, ITPR3, KCNA1, KCNA2, KCNA3, KCNA4, KCNA5, KCNA10, KCND2, KCND3, KCNE1, KCNJ2, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ12, KCNJ13, KCNJ14, KCNJ15, KCNJ16, KCNK2, KCNK3, KCNN1, KCNN4, KCNQ1, KCNS1, KCNS2, KCNS3, SLC11A2, NTSR1, P2RX7, PDE4B, PDE4D, PDPK1, PIK3C2A, PIK3CG, PLN, PRKAB2, PRKACA, PRKCE, PRKD1, PTPN3, PTPN6, REST, RHAG, RHCE, RHD, RYR1, RYR2, RYR3, S100A1, SCN1A, SCN2B, SCN3A, SCN4B, SCN5A, SCN8A, SCN10A, SCNN1A, SCNN1B, SCNN1D, SCNN1G, CCL21, XCL1, SLC5A5, SLC8A1, SLC8A3, SLC9A1, SLC9A3, SLC9A5, SLC11A1, SLC22A1, SLC22A3, SLC22A2, SLC22A5, SLN, SNCA, SNTA1, ABCC8, SURF1, TRAPPC10, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, SUMO1, UQCRC1, UQCRFS1, UQCRH, TRPV1, YWHAH, SLC30A1, SLC30A2, ZP3, CUL5, KCNAB2, KCNK5, SLC4A4, ATP6V0E1, HAP1, RGN, ATP6V0D1, COX7A2L, SLC24A1, KCNAB3, ATP6V1F, SLC9A3R1, COX5A, KCNK6, GSTO1, AKAP7, AKAP6, ATG5, ATP6V1G1, ATP5J2, OXSR1, KCNE2, KCNE3, HCN4, ABCC9, AKAP9, KCNMB2, TRDN, CACNG2, RAPGEF3, ATP5H, SLC9A6, CHERP, ATP5L, UQCR11, WWP2, CACFD1, IL1RAPL1, CORO1A, SCN11A |
1974 | GO:0000086 | 0.00 | 1.98 | 49.24 | 69 | 118 | G2/M transition of mitotic cell cycle | BIRC5, ATM, BACH1, CCND1, CCNB1, CCNH, CDC25C, CDK4, CDKN1A, CDKN2A, CENPF, CSNK1D, GADD45A, DYNC1H1, DYNC1I2, DNM2, ENSA, EP300, HSP90AA1, RAB8A, FOXO4, PPP1R12A, PPP1R12B, NUMA1, ODF2, PBX1, PCM1, ABCB1, PPP2R1A, PPP2R2A, PRKACA, PRKAR2B, PRKCQ, RAD51B, RBBP4, RPS27A, SKP1, SKP2, SMARCD3, AURKA, TAF2, TPD52L1, TUBA4A, UBB, WEE1, YWHAG, ALMS1, TUBA1A, CUL1, OFD1, PPM1D, SSNA1, DYNLL1, RAB11A, PHOX2B, LATS1, CCNB2, CEP135, CEP57, CCP110, CKAP5, SFI1, ACTR1A, AKAP9, TUBGCP3, KHDRBS1, ARPP19, CHEK2, DCTN3 |
1975 | GO:0000077 | 0.00 | 1.98 | 39.23 | 55 | 94 | DNA damage checkpoint | ATM, ATR, CCND1, BRCA1, CDC5L, CDKN1A, ATF2, CRY1, FOXO4, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RAD1, RBBP8, RPS27A, SOX4, TP73, UBB, XPC, CUL4A, CDC14B, TP63, PEA15, CRADD, TAOK2, PSMF1, CLOCK, BRE, PSMD6, FEM1B, PSME3, CHEK2 |
1976 | GO:0006119 | 0.05 | 1.98 | 12.10 | 17 | 29 | oxidative phosphorylation | AK2, ATP5C1, ATP5D, COX4I1, COX8A, COX15, DLD, SDHC, SNCA, SURF1, TAZ, UQCRB, UQCRC1, UQCRC2, UQCRH, COX5A, COQ7 |
1977 | GO:0009620 | 0.05 | 1.98 | 12.10 | 17 | 29 | response to fungus | ANG, CD86, CTSG, DEFA1, HRG, LTF, S100A8, S100A9, S100A12, SYK, TAC1, VIP, BCL10, ATG5, SPON2, GNLY, MALT1 |
1978 | GO:0048644 | 0.05 | 1.98 | 12.10 | 17 | 29 | muscle organ morphogenesis | CNTF, COL3A1, COL11A1, DSP, S1PR1, NRG1, RBPJ, ISL1, SMAD7, PROX1, RXRA, RYR2, TNNC1, TNNI3, TNNT2, WNT2, HAND1 |
1979 | GO:0070373 | 0.05 | 1.98 | 12.10 | 17 | 29 | negative regulation of ERK1 and ERK2 cascade | ATF3, CRYBA1, DLG1, DUSP1, FBLN1, RAPGEF1, IGF1, PHB, PTPN1, PTPRR, EZR, ITGB1BP1, KLF4, SLC9A3R1, RANBP9, TNIP1, RGS14 |
1980 | GO:0001755 | 0.02 | 1.98 | 17.11 | 24 | 41 | neural crest cell migration | ACVR1, EDN3, EDNRB, GDNF, HIF1A, ISL1, LAMA5, KITLG, NRTN, SEMA3F, SHH, SOX10, TWIST1, SEMA3B, SEMA7A, PHOX2B, HAND2, SEMA3E, ZEB2, SEMA3A, SEMA6C, SEMA6B, SEMA4F, SEMA4B |
1981 | GO:0022898 | 0.00 | 1.98 | 42.15 | 59 | 101 | regulation of transmembrane transporter activity | ACTN4, ATP1A2, ATP1B3, FXYD2, BCL2, BMP4, CACNB4, CALM3, CASQ2, CAV3, CFTR, CTSS, DNM2, STOM, GRK6, GSTM2, HRC, INS, KCNE1, KCNJ11, KCNQ1, KCNS1, KCNS2, NTSR1, PDE4B, PDE4D, FXYD3, PLN, PRKACA, PRKCE, RELN, PTAFR, PTPN3, RYR2, S100A1, SCN2B, SCN4B, SLC9A1, SLN, TWIST1, SUMO1, YWHAH, RIPK1, HAP1, RGN, SLC9A3R1, NRXN1, GSTO1, AKAP7, AKAP6, OXSR1, KCNE2, KCNE3, AKAP9, TRDN, CACNG2, RAPGEF3, AHCYL1, WWP2 |
1982 | GO:1903050 | 0.01 | 1.98 | 19.95 | 28 | 48 | regulation of proteolysis involved in cellular protein catabolic process | APC, ATM, BUB1, BUB1B, CENPF, CSNK2A1, CSNK2A2, DUSP1, GPX1, UBE2K, HSP90AB1, MAD2L1, OPHN1, PRKACA, PRKCG, SDCBP, SHH, SMARCC1, TMF1, ZNF207, USP14, ZW10, BUB3, BAG5, MAD2L2, GIPC1, USP19, GLMN |
1983 | GO:0099504 | 0.01 | 1.98 | 22.12 | 31 | 53 | synaptic vesicle cycle | AMPH, CACNA1A, CDK5, CLCN3, DDC, DNM1, GRN, OPHN1, P2RX7, PFN2, SEPT5, RAB3A, RAP1A, ITSN1, SNAP25, SNCA, STXBP1, SYN1, SYT1, DOC2A, CADPS, STX11, SNAP23, SYNJ1, SNAP29, RIMS2, SNPH, RIMS3, UNC13B, CPLX2, CPLX1 |
1984 | GO:0042742 | 0.01 | 1.97 | 24.97 | 35 | 60 | defense response to bacterium | ANXA3, BCL3, BPI, CD4, CEBPE, CYBA, COCH, F2RL1, FCER1G, HP, IFNG, RBPJ, IL10, SERPINE1, CFP, PRG2, RAB1A, S100A8, S100A9, S100A12, CCL20, CXCL6, SELP, SFTPD, SLC11A1, SPN, SYK, TMF1, TNFRSF1A, ADAMTS4, CXCL13, GNLY, ADAMTS5, CD160, TUSC2 |
1985 | GO:0051129 | 0.00 | 1.97 | 67.23 | 94 | 162 | negative regulation of cellular component organization | ACTN4, ACVRL1, ADCY6, ANXA2, APOA1, APOC2, ARF6, ARHGAP4, CDC42, CDK5, AP2M1, CLU, CLTC, CLDN7, DAB2, DCC, ACE, DDX3X, DFFA, DNM2, DPP4, DPYSL3, LPAR1, EFNA1, EIF4EBP1, EPHA4, EPHA7, FAP, FBLN1, EFEMP1, GAK, GDI1, GFAP, GFI1, FOXA2, HPN, HRG, DNAJB2, HSPA8, INS, ITGA3, ITGB1, KCNE1, SMAD6, SMAD7, CITED1, PEX14, PPM1A, PRKD1, PRKCZ, PTGER4, PTN, PTPRZ1, PEX5, RAC1, RAF1, RAP1GAP, RNF6, SALL1, CCL21, SDCBP, SEMA3F, SLIT1, SLN, SORL1, TNR, TTC3, NR1H2, VDAC2, VIM, YWHAH, SEMA3B, PICALM, OGT, NUMB, CFLAR, CBFA2T2, ITGB1BP1, NRXN1, TMEM59, BAG5, AATK, RAPGEF2, SEMA3E, KIAA0319, SEMA3A, RAPGEF3, CARM1, SEMA6C, SEMA6B, SEMA4F, SEMA4B, CIT, STRAP |
1986 | GO:0060627 | 0.03 | 1.97 | 15.65 | 22 | 38 | regulation of vesicle-mediated transport | AKT2, DNM1, ACSL3, GAS1, INSIG1, PARK2, PRKAA1, MAPK3, RDX, SLAMF1, SORL1, UVRAG, EZR, RAB11A, USP6, RAB11B, GOSR1, C2CD5, SEC24B, EHD1, BVES, CORO1A |
1987 | GO:0050680 | 0.01 | 1.97 | 25.02 | 35 | 60 | negative regulation of epithelial cell proliferation | ACVRL1, APC, APOH, BMP4, KLF9, CAV2, KRIT1, CDK6, ATF2, CTSV, DLG1, EFNB2, EREG, GPC3, SFN, HPN, KRT4, MEN1, SERPINF1, PTCH1, PTN, PTPRM, RAP1GAP, RB1, SNAI2, SOX2, SOX9, SPARC, STK11, NR2F2, VDR, SCG2, IFT88, RGN, STRAP |
1988 | GO:0001570 | 0.03 | 1.96 | 15.02 | 21 | 36 | vasculogenesis | EPHA2, EMP2, HAS2, HHEX, JUNB, KDR, CITED1, NTRK2, PTPRJ, RAP1A, SHH, T, TNNI3, VEGFA, FZD4, SGPL1, QKI, RAPGEF2, CUL7, RAMP2, GLMN |
1989 | GO:0071174 | 0.03 | 1.96 | 15.02 | 21 | 36 | mitotic spindle checkpoint | APC, ATM, BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DUSP1, MAD2L1, UBE2D1, ZNF207, CDC23, CDC16, ZW10, BUB3, ANAPC10, MAD2L2, UBE2C |
1990 | GO:1902100 | 0.03 | 1.96 | 15.02 | 21 | 36 | negative regulation of metaphase/anaphase transition of cell cycle | APC, ATM, BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DUSP1, MAD2L1, UBE2D1, ZNF207, CDC23, CDC16, ZW10, BUB3, ANAPC10, MAD2L2, UBE2C |
1991 | GO:0009968 | 0.00 | 1.96 | 115.76 | 161 | 281 | negative regulation of signal transduction | ACVR1, ADAR, AP2A1, AP2B1, AES, NR0B1, AMHR2, APOA1, AVP, BAX, CCND1, PRDM1, BRCA1, CAV2, CBL, CBLB, CDC42, AP2M1, AP2S1, CLTA, COL2A1, CRY2, CSF2, CTH, CTNNA1, CTNND1, CX3CR1, DAB2, ECM1, ELF1, CTTN, EPS15, EYA1, FGA, FGF9, FGG, FYN, IFI6, GAS6, GATA3, GDNF, GPC1, GRB2, HGF, NRG1, HHEX, HIC1, ONECUT1, HRG, ICAM1, IGFBP2, IGFBP3, IGFBP5, IGFBP6, IHH, IL1A, IL1RN, ITGA6, ISL1, ITGA1, ITGAV, LTF, SMAD3, SMAD6, SMAD7, CITED1, CNOT2, SERPINE1, PAWR, PDPK1, PF4, PPP1CA, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RAF1, RFNG, RGS1, RGS10, RGS16, RPS27A, ATXN7, CX3CL1, SFRP4, SHH, SIAH2, SIX3, SLAMF1, SLIT3, SMARCA4, SOX2, SOX9, SOX10, TYRO3, UBB, NR1H2, WNT1, WNT11, PXDN, SCG2, RAB7A, STAM, FZD6, MADD, NUMB, PEA15, RGS11, RGS9, DLK1, CFLAR, ARHGEF7, LATS1, RQCD1, DHRS3, S1PR2, ZFYVE9, ONECUT2, PSMF1, NR1D1, CLOCK, PHF14, ADAMTSL2, ZNF536, RB1CC1, PSMD6, RBX1, HMGXB4, G3BP1, PSME3, TRIB1, STAM2, FSTL3, TRAIP, APC2, ACAA2, MAD2L2, STRAP, PHB2 |
1992 | GO:1903531 | 0.01 | 1.96 | 22.90 | 32 | 55 | negative regulation of secretion by cell | ABAT, AGTR2, ANGPT1, ANXA1, ANXA4, APOA1, CNR1, F2R, F2RL1, FBLN1, GAS6, IFNA2, IL10, TNFRSF9, INS, P2RY1, SRGN, PTGER4, RAP1A, CX3CL1, SNCA, STXBP3, SYT4, TNFSF4, TNFRSF4, EZR, SLC30A1, VAMP8, CD84, NR1H4, ERP29, IL1RAPL1 |
1993 | GO:0090150 | 0.00 | 1.96 | 42.24 | 59 | 102 | establishment of protein localization to membrane | ARF6, ASNA1, BAD, BAX, BBS1, BBS2, BCL2, BCL2L1, BID, CASP8, CAV3, CDH1, DLG1, EPHA2, ACSL3, FLOT2, GOLGA4, SFN, HSPA4, HSP90AA1, IFNG, ITGA3, ITGB1, JUP, KRT18, LAMA5, OXA1L, PDPK1, PPP3R1, MAPK8, RAB13, RDX, CLIP1, S100A10, SLC12A1, TNFRSF1A, TSC2, VIL1, EZR, WRB, YWHAG, YWHAH, YWHAZ, UBL4A, BLZF1, DYNLL1, RAB11A, RAB11B, SLC9A3R1, NRXN1, TMEM59, BCL2L11, ARFRP1, RAMP3, AGR2, SORBS1, VAMP5, RAB31, RER1 |
1994 | GO:0072524 | 0.00 | 1.95 | 27.96 | 39 | 67 | pyridine-containing compound metabolic process | ALDOB, ALDOC, AOX1, ARNT, BPGM, DLD, ENO2, GAPDH, GPD1, HIF1A, HK2, IDH1, IGF1, INS, LDHA, MDH1, MDH2, OGDH, P2RX7, PFKFB2, PFKFB4, PGAM2, PGD, PGK1, PGK2, PGM1, PPP2R5D, PRKAA1, PTGIS, RPE, STAT3, PDHX, OGT, KCNAB2, PDXK, KYNU, TP53I3, HDAC4, ECD |
1995 | GO:0098727 | 0.00 | 1.95 | 27.96 | 39 | 67 | maintenance of cell number | APC, ASCL2, BCL9, BMPR1A, ZFP36L2, CDX2, DDX6, EIF4E, ELAVL1, EPHA1, FGFR3, HES1, IGF1, RBPJ, KIT, CNOT2, PAX2, PBX1, PCM1, PRRX1, PROX1, RAF1, SALL1, SOX2, SOX4, SOX9, STAT3, TAL1, KLF10, NR2E1, PAX8, SMC1A, EOMES, FZD7, CUL4A, SMC3, KLF4, STAG2, SIX2 |
1996 | GO:0007346 | 0.00 | 1.95 | 88.50 | 123 | 213 | regulation of mitotic cell cycle | APC, ATM, ATRX, BCL2, BCL2L1, BID, BMP4, BUB1, BUB1B, CAV2, CDC20, CDC25C, CDC27, CDC42, CDKN1A, CDKN2A, CENPE, CENPF, ATF2, CSNK2A1, CSNK2A2, CYLD, BRINP1, DDB1, DLG1, DUSP1, E4F1, ERCC3, FGFR3, GAS1, PRMT2, SMAD3, FOXO4, OVOL1, CHMP1A, PIM1, PRCC, PRKCQ, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTCH1, PTPN3, PTPN6, RPA3, RPL24, RPS27A, SDCBP, SETMAR, SKP1, SMARCA4, SOX4, STK10, DYNLT3, TOP2A, TP73, UBB, UBE2D1, XPC, ZNF207, FZD3, SMC1A, CUL1, CDC14A, CDK13, TP63, TNKS, CDC23, CRADD, HDAC3, CDC123, CDC16, ZW10, BUB3, TAOK2, SLC9A3R1, PSMF1, MAD2L1BP, KNTC1, SLK, CUL7, PSMD6, OXSR1, PARP3, TOM1L1, CTDSP2, RAD50, PSME3, CTDSPL, ANAPC10, MAD2L2, STK25, PDPN, PTTG2, PIM2, CIT, ZWINT, MAP4K5, CHEK2, ECD |
1997 | GO:0030111 | 0.00 | 1.95 | 70.53 | 98 | 169 | regulation of Wnt signaling pathway | ABL2, AES, APC, XIAP, ARNTL, CCND1, COL1A1, CSNK1D, CSNK1G2, CSNK2A1, CTNND1, CTNND2, CYLD, DAB2, DLX5, EDA, EMD, FGF9, FGFR3, RAPGEF1, HHEX, HIC1, IGFBP2, IGFBP6, RBPJ, ILK, ISL1, ITGA3, JUP, SMAD3, CITED1, PARK2, PPM1A, PPP1CA, PPP2R1A, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SALL1, SFRP4, SFRP5, SHH, SIAH2, SIX3, SNAI2, SMARCA4, SOX2, SOX4, SOX9, SOX10, STK11, TSC2, UBB, WNT1, WNT2, WNT11, WNT2B, FZD5, FZD6, CUL3, TNKS, LATS1, PSMF1, USP34, ZEB2, PSMD6, RBX1, FRAT1, HMGXB4, G3BP1, ATP6AP2, PSME3, APC2, MAD2L2 |
1998 | GO:0050714 | 0.00 | 1.95 | 33.71 | 47 | 81 | positive regulation of protein secretion | ABL2, ACHE, AGTR2, ALOX15B, ANG, APBB1, ARF1, BMP6, C5, CASP5, CD2, CD14, CD58, F2R, F2RL1, FCN1, FGA, FGG, FGR, GATA3, IFNG, IGF1, IL1A, IL1B, IL10, IL13, INS, KCNN4, P2RX7, PAEP, PPID, PRKCQ, PRKCZ, PTGER4, SYK, TWIST1, TNFSF4, TNFRSF4, NR1H2, VEGFC, EZR, ADAM9, IL1RL1, STXBP5L, TRIM16, SEC24A, GLMN |
1999 | GO:0001843 | 0.01 | 1.95 | 22.95 | 32 | 55 | neural tube closure | BBS4, BMP4, KAT2A, ARHGAP35, OPA1, PAX2, PFN1, PRKACB, PTCH1, PTK7, RALA, RARA, SALL1, SDC4, STIL, SPINT1, ST14, T, TSC1, TSC2, TULP3, TWIST1, KDM6A, ZIC2, FZD3, FZD6, BCL10, ZEB2, SEC24B, DEAF1, SPINT2, GLMN |
2000 | GO:0098792 | 0.01 | 1.95 | 22.95 | 32 | 55 | xenophagy | ANXA5, CA7, COX8A, CPA3, CLDN7, EIF2S1, STOM, FCGR3B, FGF7, SLC37A4, KCNQ1, MDH1, NTHL1, PDK4, SERPINB10, SCN1A, SNRPD1, STAT2, ZNF189, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H3F, CHST3, NUP93, PHYHIP, IST1, FGFBP1, CSPG5 |
2001 | GO:0010906 | 0.02 | 1.95 | 17.93 | 25 | 43 | regulation of glucose metabolic process | ADRA1B, AKT2, BPGM, GCG, GCGR, KAT2A, GPLD1, IGF1, IGF2, IGFBP3, IGFBP5, INS, KHK, PDK4, ENPP1, PGAM2, PPP1CA, DYRK2, OGT, KAT2B, RGN, NR1D1, EPM2AIP1, SORBS1, ARPP19 |
2002 | GO:0072175 | 0.00 | 1.95 | 30.88 | 43 | 74 | epithelial tube formation | BBS4, BMP4, CASP8, GATA3, KAT2A, GDNF, ARHGAP35, HIF1A, OPA1, PAX2, PFN1, PRKACB, PTCH1, PTK7, RALA, RARA, SALL1, SDC4, STIL, SIX1, SOX4, SOX9, SOX11, SPINT1, ST14, T, TSC1, TSC2, TULP3, TWIST1, KDM6A, ZIC2, PAX8, FZD3, FZD6, BCL10, HAND1, ZEB2, COQ7, SEC24B, DEAF1, SPINT2, GLMN |
2003 | GO:0071103 | 0.00 | 1.95 | 57.59 | 80 | 138 | DNA conformation change | ANXA1, ATRX, CCNB1, CDKN2A, CENPA, CHD1, CHD2, CHD3, CHD4, DDX1, DDX3X, DHX9, DDX11, DFFB, ERCC3, CENPI, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, H3F3B, HIST1H1A, HHEX, HMGA1, CHMP1A, PRM2, PURA, RAD51, RBBP4, SET, SOX9, SUPV3L1, TOP1, TOP2A, TSPY1, WRN, CHAF1B, HIST1H4I, CDC45, HIST1H2BG, HIST1H2BL, HIST1H2BM, HIST1H2BF, HIST1H2BH, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HAT1, HIST1H3F, HIST1H2BJ, H1FX, AIFM1, RECQL5, RECQL4, CHD1L, GINS1, SMC4, RAD50, G3BP1, ERN2, CTCF, RUVBL2, ASCC3, PAPD7, BAZ2A, OIP5 |
2004 | GO:0015672 | 0.00 | 1.94 | 128.04 | 177 | 308 | monovalent inorganic cation transport | ACTN4, ADORA1, ADRB2, SHROOM2, ARF1, ATF4, ATP1A2, ATP12A, ATP1B3, FXYD2, ATP4A, ATP4B, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, ATP5O, HCN2, CASQ2, CAV3, CD63, CNGA1, CNGA2, COX4I1, COX5B, COX6A1, COX6A2, COX6B1, COX7A1, COX7B, COX7C, COX8A, COX15, DLG1, DNM2, DPP6, EDN3, STOM, GJA5, HPN, HTR3A, IL13, KCNA1, KCNA3, KCNA4, KCNA5, KCNA10, KCND2, KCND3, KCNE1, KCNJ2, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ12, KCNJ13, KCNJ14, KCNJ15, KCNJ16, KCNK2, KCNK3, KCNN1, KCNN4, KCNQ1, KCNS1, KCNS2, KCNS3, SLC11A2, P2RX4, P2RX7, PER1, FXYD3, PRKCE, PRSS8, PTPN3, REST, SCN1A, SCN2B, SCN3A, SCN4B, SCN5A, SCN8A, SCN10A, SCNN1A, SCNN1B, SCNN1D, SCNN1G, SGK1, SLC5A2, SLC5A3, SLC5A5, SLC6A8, SLC8A1, SLC8A3, SLC9A1, SLC9A3, SLC9A5, SLC10A1, SLC10A2, SLC12A1, SLC12A3, SLC12A4, SLC13A1, SLC15A1, SLC15A2, SLC34A1, SLC20A1, SLC20A2, SNTA1, ABCC8, SURF1, TRAPPC10, TRPM2, TSC1, TWIST1, SUMO1, UCP1, UQCRC1, UQCRFS1, UQCRH, VIP, YWHAH, KCNAB2, KCNK5, SLC4A4, SLC5A6, ATP6V0E1, SLC25A14, SLC13A2, ATP6V0D1, COX7A2L, SLC24A1, KCNAB3, ATP6V1F, SLC9A3R1, COX5A, KCNK6, AKAP7, AKAP6, SLC4A8, ATP6V1G1, ATP5J2, OXSR1, SLC23A2, KCNE2, KCNE3, HCN4, ABCC9, SGK2, AKAP9, KCNMB2, RAPGEF3, ATP5H, SLC9A6, SLC35A1, SLC34A2, ATP5L, AHCYL1, UQCR11, SLC38A3, WWP2, SCN11A |
2005 | GO:0048041 | 0.05 | 1.94 | 12.92 | 18 | 31 | focal adhesion assembly | ACTN1, ACVRL1, ARHGAP6, BCL2, EFNA5, CTTN, EPHA3, GPM6B, ITGA2, LAMA5, PDPK1, SLC9A1, TRIP6, ARHGEF7, TAOK2, SLK, SORBS1, FERMT2 |
2006 | GO:0002250 | 0.00 | 1.94 | 45.30 | 63 | 109 | adaptive immune response | BCL3, TNFRSF17, C1QBP, SERPING1, C1QA, C1QB, C1QC, C1S, C5, C8B, CAMK4, CD1B, CD6, CD7, CD8A, CD86, CD74, CD79B, CLU, CR2, CTLA4, CTSS, CD55, DLG1, GPR183, EMP2, ADGRE1, ERCC1, FCGR1B, FGA, FYN, GATA3, ICAM1, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IL18, CD46, PIK3CB, PIK3CG, PRKCB, RAB27A, RAG1, RELB, SLAMF1, SYK, TSC1, LAT2, KDM5D, EOMES, STX11, IL18R1, CD84, BCL10, RNF8, EXO1, IL18BP, EBI3, CLEC10A, BATF, CXCL13 |
2007 | GO:0007605 | 0.00 | 1.94 | 33.80 | 47 | 81 | sensory perception of sound | ATP2B2, ALDH7A1, ATP6V1B1, CDKN2D, CHRNB2, COL1A1, COL2A1, COL4A3, COL11A1, CRYM, DFNA5, COCH, DIAPH1, DNM1, EYA4, EYA1, GABRB2, GJB2, GPX1, HEXB, HPN, ICAM1, KCNE1, KCNQ1, KIT, SLC26A4, ATP8B1, SERPINB6, RPL38, SCN8A, SIX1, SLC12A2, SNAI2, SOD1, SOX2, TBL1X, ZNF354A, UCN, USH2A, CLRN1, WFS1, FZD4, SLC9A3R1, FAM65B, WDR1, GJB6, KPTN |
2008 | GO:0033554 | 0.00 | 1.94 | 61.39 | 86 | 153 | cellular response to stress | ANXA1, ANXA5, ARG1, ASS1, BMP4, C5, CA2, CA7, CAPS, CBS, CHUK, COX8A, DNM2, DNMT3B, DPEP1, DUSP4, DUSP7, DUSP9, ECT2, ELK1, STOM, ETS1, ETV5, F3, FCGR3B, SLC37A4, BLOC1S1, GJB2, GSTM1, GSTM2, GUCY1B3, HAS2, HK2, INSIG1, IRAK2, KRT15, MDH1, SLC11A2, PAX2, PENK, PGK2, SERPINB10, PPP2R5D, PRKD1, PRKG1, PTGER4, RPS6KA2, SFRP4, SIPA1, SKP1, SLCO1A2, SLC22A3, SNRPD1, SNRPF, SRF, STAT2, STAU1, STK10, PRDX2, TNFAIP3, NR2C2, ZNF189, CUL1, MAPKAPK5, PRKRA, IL18RAP, KAT2B, RPS6KA5, ARHGEF6, SLK, RIMS3, PHYHIP, IST1, RB1CC1, FGFBP1, SH2D3C, SH2D3A, IL18BP, DHRS2, TRIB1, COQ7, CSPG5, PRDX3, HSF2BP, CDC37, ADAMTS7 |
2009 | GO:0097659 | 0.00 | 1.94 | 34.23 | 48 | 85 | nucleic acid-templated transcription | ANG, COX4I1, COX5B, COX6A1, COX6B1, COX7B, COX7C, COX8A, CSTF3, CTGF, GLS, SFN, GPX2, GTF3C1, GTF3C2, DRG1, PPP5C, PRKAB2, PTMA, RHEB, SRSF1, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SNRPE, SNRPF, PRDX2, TSC1, U2AF1, YWHAG, YWHAZ, SRSF9, RNGTT, COX7A2L, DDX21, GTF3C5, GTF3C4, GTF3C3, COX5A, DHX38, IVNS1ABP, RRAGA, PAPOLA, RNPS1, ADRM1, HSF2BP |
2010 | GO:0000245 | 0.05 | 1.94 | 12.94 | 18 | 31 | spliceosomal complex assembly | DDX1, SRSF1, SRSF5, SRSF6, SFSWAP, SNRPC, SNRPD1, SNRPD2, SNRPE, SRPK2, SF3A2, SRSF9, SCAF11, USP39, SRSF10, TXNL4A, SF3A3, PSIP1 |
2011 | GO:0001756 | 0.05 | 1.94 | 12.94 | 18 | 31 | somitogenesis | ATM, BMPR1A, CDX1, CDX2, EP300, KAT2A, FOXA2, SMAD3, MEOX2, OTX2, PAX1, PCDH8, T, KDM6A, XRCC2, ZEB2, ABI1, DMRT2 |
2012 | GO:0090109 | 0.05 | 1.94 | 12.94 | 18 | 31 | regulation of cell-substrate junction assembly | ACVRL1, ARHGAP6, COL16A1, EFNA5, EPHA3, GPM6B, HRG, KDR, SMAD3, PTPRJ, RAC1, S100A10, SDC4, SLC9A1, TSC1, VEGFA, ITGB1BP1, SLK |
2013 | GO:0098771 | 0.00 | 1.93 | 53.93 | 75 | 131 | inorganic ion homeostasis | ABCB7, ACO1, ADORA1, AGTR2, ALAS2, ANPEP, XIAP, APLP2, ARF1, ATP12A, ATP1B3, ATP4A, ATP6V1A, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, AVPR2, BMP6, CA2, CA7, CFTR, CLCN3, CLN5, COMT, CP, EPB42, FECH, FGFR4, FTL, HIF1A, HPX, IREB2, KCNJ2, KCNJ10, LTF, NUBP1, SLC11A2, OTC, PDK4, ENPP1, SLC26A4, PPT1, PTGER4, RHAG, SCNN1A, SCNN1B, SCNN1G, SFRP4, SGK1, SLC9A1, SLC9A3, SLC9A5, SLC34A1, SOD1, UPK3A, RAB7A, FGF23, PICALM, CYP4F2, ATP6V0E1, ATP6V0D1, XPR1, ATP6V1F, SLC9A3R1, ABCG2, ATP6V1G1, HEPH, ABCB6, SGK2, SLC9A6, SLC34A2, CLDN16, CORIN, SLC26A1 |
2014 | GO:0045596 | 0.00 | 1.93 | 36.63 | 51 | 89 | negative regulation of cell differentiation | NR0B1, AREG, ARNTL, ZFP36L2, RUNX1T1, CDK6, COL5A1, COL5A2, GABPA, GATA3, PRMT1, IAPP, IGFBP5, RBPJ, INSIG1, ITPKB, KRAS, SMAD3, MEN1, ENPP1, PF4, PTCH1, PTHLH, RARB, SORT1, S100B, SNAI2, SNAI1, STAT5B, TWIST1, USH2A, WNT1, FGF23, HIST1H4I, FZD7, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CHRD, HAND2, IQCB1, GAS2L1, SIX2, CCDC85B, ADAMTS7 |
2015 | GO:0002366 | 0.00 | 1.93 | 32.45 | 45 | 78 | leukocyte activation involved in immune response | ADA, AP1G1, ANXA1, BCL3, CD28, CD80, CD86, CD40, GPR183, ERCC1, GATA3, HLX, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IL10, ITGAL, CD180, CD46, PRKCZ, PTGER4, RAB27A, RARA, RELB, SLC11A1, TSC1, TNFSF4, UNG, WHSC1, EOMES, TNFSF13, RIPK2, IL18R1, PGLYRP1, TNFSF18, RNF8, EXO1, IL27RA, BATF, CORO1A |
2016 | GO:0050830 | 0.03 | 1.93 | 15.86 | 22 | 38 | defense response to Gram-positive bacterium | ACP5, ANG, TNFSF8, CD36, CRP, CTSG, DEFA1, FAU, FCN2, FGR, P2RX7, RNASE3, RPL39, TAC1, VIP, HIST1H2BG, HIST1H2BF, HIST2H2BE, RIPK2, HIST1H2BJ, PGLYRP1, IL27RA |
2017 | GO:0072583 | 0.03 | 1.93 | 15.86 | 22 | 38 | clathrin-mediated endocytosis | AP2A1, AP2B1, AMPH, CDK5, AP2M1, AP2S1, CLTA, DAB2, DNM1, GRN, HIP1, ITGA4, OPHN1, PIK3CB, ITSN1, SNCA, SYT1, PICALM, SYNJ1, DNAJC6, SNAP91, TNK2 |
2018 | GO:0090114 | 0.03 | 1.93 | 15.86 | 22 | 38 | COPII-coated vesicle budding | AREG, CD59, CSNK1D, CTSZ, GOLGA2, GRIA1, INSIG1, LMAN1, PPP6C, RAB1A, TRAPPC10, CUL3, USO1, VAPB, VAPA, SEC22B, GOSR2, PREB, SEC24B, SEC23A, SEC24A, TMED10 |
2019 | GO:0050806 | 0.01 | 1.92 | 26.69 | 37 | 64 | positive regulation of synaptic transmission | ABAT, ADORA1, CHRNB2, CX3CR1, DBI, DNM1, GFAP, GIP, GLUL, GRIN2A, IFNG, ITPR3, KISS1, NTRK1, NTRK2, NTSR1, OXT, PARK2, PRKCZ, RELN, PTGER4, PTN, RAB3B, S100B, SLC8A3, SNAP25, SNCA, STAU1, SYT1, TACR2, NR2E1, TNR, SYNJ1, NRXN1, RIMS2, UNC13B, RGS14 |
2020 | GO:0009791 | 0.02 | 1.92 | 18.75 | 26 | 45 | post-embryonic development | ACO1, ACVR2B, BCL2, PRDM1, BMP4, CLPS, CYP1A2, DHCR7, EMX1, ERCC1, FLT3, GATA3, GNAQ, IGF2R, INPPL1, ITPR1, LLGL2, RAB3A, SEPP1, SLC8A1, TBCE, TP73, USP9X, DLK1, SGPL1, ATG7 |
2021 | GO:0051248 | 0.00 | 1.92 | 269.18 | 366 | 645 | negative regulation of protein metabolic process | A2M, SERPINA3, ADAR, ADARB1, AHSG, AKT2, AMBP, ANG, ANGPT1, ANXA2, APBB1, APC, APCS, BIRC3, XIAP, BIRC5, APLP2, APOA4, AQP1, SERPINC1, ATF3, ATF4, ATM, AVP, BAX, BCL3, BDKRB2, BMP4, BRCA1, BST2, BUB1, BUB1B, TSPO, SERPING1, C3, C5, CALM3, CASP8, CAV3, SERPINH1, CCNB1, CD44, CD59, CDC20, CDC27, CDK5, CDKN1A, CDKN2A, CDKN2C, CDKN2D, CENPF, CHAD, CIRBP, CISH, CLU, COL4A3, COL6A3, CR1, CRY1, CRY2, CRYAB, CRYBA1, CSNK2A1, CSNK2A2, CST1, CST6, CD55, DCN, GADD45A, DDX3X, DHCR24, DLG1, DLG2, DLG3, DNMT1, DNMT3B, DPEP1, HBEGF, DUSP1, DUSP4, DUSP5, DUSP7, DUSP9, ECM1, EDNRB, EIF2S1, EIF4E, EIF4EBP1, EIF4EBP2, SERPINB1, EPHA1, EPRS, F2RL1, FBLN1, FGA, FLNA, FLOT2, FYN, IFI6, GAPDH, GAS1, GAS6, GHSR, GPC3, GNAQ, SFN, GP1BA, GPS2, GPX1, GRB7, RAPGEF1, GRIN2A, SERPIND1, HGF, NRG1, HHEX, HMGCR, HPN, HRG, DNAJB2, HSPB1, HSP90AB1, IDE, IFI16, IGF1, IGF1R, IGFBP3, IGFBP5, IL1B, IL10, ILK, INHA, INS, EIF3E, IREB2, ITGAV, ITIH1, ITIH2, ITIH3, ITIH4, JARID2, JUN, KNG1, LIMK1, CAPRIN1, MAD2L1, SMAD1, SMAD3, SMAD6, SMAD7, CD46, MEN1, CNOT2, NTF3, NTRK3, OPHN1, P2RX7, PEBP1, SERPINE1, PARK2, PAX2, PDCL, SERPINA5, PCP4, PDE4D, ENPP1, PDPK1, SERPINF1, PER1, PHB, PI3, SERPINB6, SERPINB8, SERPINB9, SERPINB10, SERPINI1, SERPINB13, PPP1R1A, PPP2R1A, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCE, PRKCG, PRKCZ, EIF2AK2, DNAJC3, PROS1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN1, PTPN3, PTPN6, PTPRJ, PTPRR, PURA, PZP, RAF1, RAG1, RAN, RARA, RB1, RBM3, RBM4, RGS2, RPS3, RPS6KA1, RPS6KA3, RPS27A, SERPINB3, SERPINB4, SDCBP, SET, SFTPD, SHH, SIAH2, SLPI, SMARCC1, SMPD1, SNCA, SNRNP70, SNTA1, SORL1, SOX4, SPINK1, SPINT1, SRP9, TAF7, TARBP2, SERPINA7, NR2F2, TNFAIP3, TP73, TRAF2, TSC1, TSC2, TWIST1, UBB, UBE2D1, UCN, USP4, NR1H2, VEGFA, VIL1, EZR, VTN, WNT1, YWHAG, ZFP36, ZNF207, AKAP1, PICALM, RECK, CUL3, OGT, PRKRA, CDC23, SERPINB7, TRADD, URI1, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, CFLAR, HDAC3, KAT2B, CDC16, EIF2B4, EIF2B3, EIF2B5, HAP1, SOCS3, USP14, RGN, LATS1, RQCD1, ZW10, BUB3, ITGB1BP1, SOCS6, KLF4, TRIP12, CNOT8, SLIT2, SLC9A3R1, QKI, EIF2AK3, ATG5, PSMF1, TMEM59, BAG5, BAG4, GMFG, KDM4A, PUM1, RASSF2, SFI1, RGP1, PPP1R26, PSMD6, ACOT8, HDAC6, RANBP9, CTDSP2, FRY, FARP1, PSME3, PRG4, CTDSPL, TRIB1, TNIP1, ABCA7, HMG20B, ANAPC10, PRG3, PIAS3, CD2BP2, OLFM1, MAD2L2, CRTAP, ATG7, HEXIM1, RGS14, IGF2BP3, SPINT2, PTTG2, GIPC1, ZMYND11, SPINT3, USP19, PRDX3, OS9, SPINK5, UBE2C, GLMN, STRAP, STK38 |
2022 | GO:0007015 | 0.00 | 1.92 | 44.06 | 61 | 106 | actin filament organization | ANG, SHROOM2, ARF1, ARF6, BCL2, CAPZA1, CAPZB, CAV3, CFL2, CTNNA1, DBN1, DIAPH1, DIAPH2, DLG1, EMP2, CTTN, F2RL1, GHSR, GRB2, HCK, HCLS1, ICAM1, INPPL1, PRKCE, PRKCI, PROX1, RAC2, CCL21, CCL24, SPTA1, SPTB, TMOD1, CLRN1, SORBS2, WASF1, LATS1, ARHGEF2, SLIT2, PICK1, GMFG, BCAR1, WDR1, ABI1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, FRY, ABI2, CDC42EP2, MAD2L2, ARPC1A, ARFGEF1, CDC42EP3, AVIL, KPTN, CDC42EP1, CORO1A, TWF2 |
2023 | GO:0022604 | 0.00 | 1.92 | 115.60 | 159 | 277 | regulation of cell morphogenesis | ACTN4, ANXA1, APOA1, ARHGAP4, BBS4, BMPR2, C1QBP, CACNA1A, CAPZB, CDC42, CDK5, CHN1, CHRNB2, COL1A1, CUX1, CYLD, DAB2, DCC, COCH, DIAPH1, DLG1, DNM2, LPAR1, EFNA1, EFNA5, CTTN, EPB42, EPHA3, EPHA4, EPHA7, EPHB3, EPS8, FBLN1, FGA, FGD1, FGG, FGR, FLNA, FYN, GAS2, GDI1, GDNF, GOLGA4, ARHGAP35, HAS2, HCK, HEXB, NRG1, FOXA2, HPN, ICAM1, ILK, ITGA7, KDR, KIT, LIMK1, TACSTD2, CAPRIN1, SMAD3, SMAD7, CITED1, NRCAM, NTRK2, NTRK3, ODF2, PARK2, PAX2, ENPP2, RELN, PTN, PTPRD, PTPRZ1, RAC1, RAC3, RAP2A, RDX, RNF6, RREB1, S100A10, S100A13, S100B, SALL1, SERPINB3, CCL24, SDC2, SDCBP, SEMA3F, SGK1, ST6GAL1, SLIT1, SLIT3, SNAI1, SPARC, SPTA1, SRF, CDKL5, STK11, SYT1, SYT4, CNTN2, NR2E1, TNR, TTC3, TWIST1, VEGFA, VIL1, EZR, XK, YWHAH, LRP8, PAX8, SEMA3B, IFT88, RND2, SEMA7A, RAB11A, ARHGEF7, HAP1, ZMYM6, NUMBL, ITGB1BP1, TAOK2, SLIT2, CPNE6, SLC9A3R1, ATG5, AATK, RAPGEF2, RIMS2, SEMA3E, IFT140, IST1, CUL7, PQBP1, ARPC2, SEMA3A, CDC42EP2, OLFM1, BAIAP2, MAD2L2, STK25, SEMA6C, SEMA6B, SEMA4F, SEMA4B, OLFM4, CDC42EP3, PDLIM5, PDPN, TBR1, SEPT9, FERMT2, CIT, CDC42EP1, IL1RAPL1, BVES, CORO1A, STRAP, TWF2 |
2024 | GO:0007292 | 0.02 | 1.92 | 18.76 | 26 | 45 | female gamete generation | ANG, ATM, BCL2, BRCA2, CCNB1, DIAPH2, ERCC1, FSHR, GDF9, HEXB, IGF1, IHH, INSL3, PDE3A, PPP2R1A, RPS6KA2, AURKA, TAF4B, ZP3, FOSL1, USP9X, PDE5A, DYNLL1, BMP15, KIAA0196, BCL2L10 |
2025 | GO:0009581 | 0.05 | 1.92 | 13.69 | 19 | 33 | detection of external stimulus | ADORA1, ATP2B2, CAV3, COL11A1, EPHB1, FYN, HPN, IGF1, ITGA2, JUP, KCNA1, KIT, NTRK1, NTSR1, PAWR, SLC12A2, SOX2, TRPV1, CSRP3 |
2026 | GO:0051093 | 0.01 | 1.92 | 20.82 | 29 | 51 | negative regulation of developmental process | AHSG, APC, ARHGDIB, BBS2, BNIP3, CD86, CDH3, CHAD, CCR1, ECM1, NR5A1, GAS6, GNAS, HIF1A, TNFRSF11B, PARK2, SRGN, RFX4, SFRP5, SIX1, SLIT1, STK11, RGN, CER1, EIF2AK3, PHF14, FIG4, RAPGEF3, RAI1 |
2027 | GO:1901988 | 0.00 | 1.92 | 35.42 | 49 | 85 | negative regulation of cell cycle phase transition | CCND1, BCL2, CDC5L, CDKN1A, PRMT2, MEN1, FOXO4, OVOL1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RB1, RPS27A, SMARCA4, SOX4, SOX11, TP73, UBB, TP63, CRADD, PSMF1, PSMD6, CTDSP2, PSME3, CTDSPL, CHEK2 |
2028 | GO:0045639 | 0.02 | 1.92 | 18.78 | 26 | 45 | positive regulation of myeloid cell differentiation | ACVR1B, ACVR2A, ARNT, ATP6AP1, CA2, CASP8, CCR1, ETS1, GNAS, HCLS1, HIF1A, PRMT1, IFNG, JUN, KITLG, PF4, PRKCA, RB1, TAL1, KLF10, ZNF16, OGT, TNFSF11, RIPK1, TRIB1, IKZF1 |
2029 | GO:0060041 | 0.00 | 1.91 | 32.55 | 45 | 78 | retina development in camera-type eye | ACHE, ACTL6A, ACVR2B, ACVRL1, APC, ATP2B1, BAX, BMP4, BMPR2, CACNA1F, CLCN2, CRX, GNAT1, GNAT2, GNB1, GPM6A, HIF1A, IHH, IMPDH1, IMPDH2, NTRK2, PAX2, SERPINF1, PROX1, PTN, PTPRM, RARB, PRPH2, RPGR, RPL24, RRM1, RS1, SIX3, SMARCA4, SMARCD3, SOX2, SOX9, NR2E1, TULP1, FZD4, PROM1, IFT140, NR2E3, IRX5, IKZF1 |
2030 | GO:0050866 | 0.00 | 1.91 | 35.47 | 49 | 85 | negative regulation of cell activation | ABAT, ADRB2, ALOX12, ANXA1, ATM, AXL, PRDM1, BMP4, BPI, CBLB, CD37, CD74, CDKN2A, CNR1, CNR2, CTLA4, CYLD, DLG1, DTX1, ERBB2, FLT3, HLX, IFNA2, IHH, IL2RA, IL10, IDO1, INHA, IRF1, PAWR, PRKAR1A, PRKG1, PTPN6, XCL1, SFTPD, SHH, SOX11, SPN, TNFAIP3, TNFSF4, TYRO3, SCGB1A1, PDE5A, CD84, PGLYRP1, TNFSF18, SOCS6, GLMN, VSIG4 |
2031 | GO:0051960 | 0.00 | 1.91 | 70.94 | 98 | 172 | regulation of nervous system development | ADCY6, ARF6, ARHGAP4, ARNTL, ASCL2, BMPR1A, CACNA1A, CDK5, CHN1, CHRNB2, CNTF, COL3A1, CTNNA1, DBN1, DCC, DDX6, DNM2, DTX1, EDNRB, EFNA1, EIF4E, EMX1, CTTN, EPHA7, EYA1, EFEMP1, FGFR3, GAK, GATA3, GDI1, GFI1, GHSR, GRID2, ISL1, MEIS1, NTF4, PBX1, PCM1, PRRX1, PRKACB, KLK6, RAC1, RAC3, RAP1GAP, RAP2A, REST, RFX4, RNF6, SDC2, SEMA3F, SIX1, SIX3, SLC6A4, SLIT1, SLIT3, SNAP25, SORL1, SOX3, SOX5, SOX9, STAT3, CNTN2, DYNLT1, NR2E1, TNR, TTC3, TULP3, VIM, XK, YWHAG, YWHAH, SEMA3B, EOMES, SOX14, CHRD, ARHGEF2, KLF4, NREP, BAG5, AATK, SEMA3E, ZNF536, KIAA0319, WDR1, PQBP1, HMG20A, SEC24B, OLFM1, CARM1, SEMA6C, SEMA6B, SEMA4F, SEMA4B, PDLIM5, TBR1, NRG3, VAX1, CIT |
2032 | GO:0048736 | 0.00 | 1.91 | 38.39 | 53 | 92 | appendage development | ALX3, ATRX, BAX, BMP4, BMPR1A, BMPR2, RUNX2, COL2A1, COMP, DLX5, DLX6, EN1, FGF8, FGF9, GJA5, GPC3, GNAQ, GNAS, HOXC10, HOXC11, HOXD11, IDUA, IHH, ITGA6, ITGB4, KRT84, AFF3, MEOX2, PAM, PBX1, PCSK5, PRRX1, PTCH1, RARA, RARB, SALL1, SHH, SOX4, SOX9, SOX11, NR2F2, TULP3, TWIST1, ZNF141, IFT88, FZD6, RECK, FOXN1, TP63, ALDH1A2, HAND2, IFT140, BCL2L11 |
2033 | GO:0032268 | 0.00 | 1.91 | 576.33 | 763 | 1381 | regulation of cellular protein metabolic process | A2M, SERPINA3, AARS, ABL2, ACO1, ACVR1, ACVR1B, ACVR2A, ACVR2B, ACVRL1, ADAR, ADARB1, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADORA1, ADRA1B, ADRA2C, ADRB2, AGTR2, AHSG, AKT2, ALK, ALOX12, AMBP, ANG, ANGPT1, ANXA2, APC, BIRC3, XIAP, BIRC5, APLP2, APOA1, AQP1, ARNT, ARR3, SERPINC1, ATF3, ATF4, ATM, ATP6AP1, AVP, AVPR2, BAD, BAX, CCND1, BCL2, BCL3, BDKRB2, BID, BMI1, BMP1, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, BOK, BRCA1, BST2, BUB1, BUB1B, TSPO, C1QBP, SERPING1, C3, C5, CALM3, CAMK2A, CAMK2G, CASP8, CASP9, CAV2, CAV3, SERPINH1, CCK, CCNB1, CCNC, CCND3, CCNE1, CCNH, CCNT1, CCNT2, CD4, CD14, CD28, CD80, CD36, CD40, CD44, CD59, CD74, CDC6, CDC20, CDC25C, CDC27, CDC42, CDK4, CDK5, CDK9, CDKN1A, CDKN2A, CDKN2C, CDKN2D, CENPE, CENPF, CHAD, CHI3L1, CIRBP, CISH, CKS1B, CLU, CCR1, CNTF, COL4A3, COL6A3, CR1, CREBL2, CRY1, CRY2, CRYAB, CRYBA1, CSF2, CSF2RB, CSNK1D, CSNK2A1, CSNK2A2, CSPG4, CST1, CST6, CTF1, CTGF, DAB2, CD55, DAZ1, DCN, ACE, GADD45A, DDX1, DDX3X, DDX6, DHCR24, DIO2, DLG1, DLG2, DLG3, DNMT1, DNMT3B, DPEP1, HBEGF, DUSP1, DUSP4, DUSP5, DUSP7, DUSP9, DYRK1A, GPR183, ECM1, ECT2, LPAR1, EDN3, EDNRA, EDNRB, EEF2, EFNA1, EFNA5, EIF2S1, EIF2B1, EPHA2, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4EBP1, EIF4EBP2, EIF4G1, EIF4G2, EIF5, EIF5A, SERPINB1, ELAVL1, EMP2, ENSA, EP300, EPHA1, EPHA4, EPHA7, EPHA8, EPHB1, EPRS, ERBB2, EREG, ERCC6, ERN1, ESR1, F2R, F2RL1, F3, F12, ACSL1, FBLN1, FCER1A, FECH, FGA, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FGG, FGR, FLT1, FLT3, FLT3LG, FLT4, FNTA, FPR1, FSHR, FYN, IFI6, GAPDH, GAS1, GAS6, GATA3, GCG, KAT2A, GDF9, GFI1, GPC3, GNAQ, GOLGA2, SFN, GP1BA, GPLD1, GPS2, GPX1, GRB2, GRB7, RAPGEF1, GRIN2A, GRM1, HIST1H1B, SERPIND1, HCLS1, HGF, NRG1, HHEX, HIP1, UBE2K, HMGCR, HPN, HPX, HRC, HRG, PRMT1, HES1, DNAJB2, HSPB1, HSP90AA1, HSP90AB1, HTR2C, ICAM1, IDE, IFI16, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF1R, IGF2, IGFBP3, IGFBP5, IL1A, IL1B, IL2RA, IL2RB, IL2RG, IL10, IL13, IL18, ILK, INHA, INS, EIF3E, IRAK1, IRAK2, IREB2, ISL1, ITGA1, ITGA2, ITGA5, ITGB1, ITIH1, ITIH2, ITIH3, ITIH4, ITPKB, JARID2, JUN, KDR, KISS1, KIT, KLKB1, KNG1, KRAS, LIMK1, LTF, CAPRIN1, MAD2L1, SMAD1, SMAD3, SMAD6, SMAD7, MARK3, CD46, MAP3K5, MEN1, KITLG, MAP3K11, PPP1R12A, CNOT2, SLC11A2, NRAS, NTF3, NTRK1, NTRK2, NTRK3, DDR2, TNFRSF11B, OPHN1, P2RX7, P2RY1, PA2G4, PEBP1, SERPINE1, PARK2, PAWR, PAX2, PDCL, SERPINA5, PCOLCE, PCP4, PDE4D, PDE6G, PDE6H, ENPP1, ENPP2, PDPK1, SERPINF1, PER1, PFN2, PHB, PI3, SERPINB6, SERPINB8, SERPINB9, SERPINB10, SERPINI1, SERPINB13, PIK3CB, PIM1, PIK3CG, PPP1CA, PPP1R1A, PPP1R2, PPP1R7, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PPP5C, PRKAA1, PRKAB2, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCE, PRKCG, PRKD1, PRKCZ, MAPK3, MAPK8, EIF2AK2, DNAJC3, PROS1, PROX1, RELN, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTAFR, PTGER4, PTPN1, PTPN3, PTPN6, PTPRA, PTPRJ, PTPRR, PTPRZ1, PURA, PZP, RAC1, RAC2, RAD51, RAF1, RAG1, RAN, RAP1A, RAP2A, RAP2B, RARA, RASA2, RB1, RBM3, RBM4, RDX, REST, RGS2, RPL38, RPS3, RPS4X, RPS6KA1, RPS6KA3, RPS6KB2, RPS27A, RRAS, RXRA, RYK, S100A8, S100A9, S100A12, SERPINB3, SERPINB4, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SDCBP, SEMG1, SET, SGTA, SHC1, SHH, SIAH2, STIL, SKP1, SKP2, SLAMF1, SLC11A1, SLPI, SNAI2, SMARCC1, SMPD1, SUMO3, SNCA, SNRNP70, SNTA1, SOD1, SORL1, SOS1, SOX2, SOX4, SOX9, SPINK1, SPINT1, SPN, SPTA1, SPTB, SREBF1, SRP9, AURKA, STK10, STK11, STYX, XCL2, SYK, TAF7, TARBP2, CNTN2, SERPINA7, NR2F2, TMF1, CLEC3B, TNFAIP3, TNFRSF1A, TNFRSF1B, TP73, TPD52L1, TRAF2, TRPS1, TSC1, TSC2, TSG101, TWIST1, TNFRSF4, UBB, UBE2D1, UBE2L3, UBE3A, SUMO1, UCN, USP4, NR1H2, UVRAG, VEGFA, VEGFB, VEGFC, VIL1, EZR, VTN, EIF4H, WFS1, WNT1, WNT11, YWHAG, ZFP36, ZNF207, ZP3, LRP8, FZD5, AIMP2, ARHGEF5, FGF23, USP5, CDK2AP1, AKAP1, SYMPK, PICALM, FZD4, FZD7, FZD8, BCAR3, RECK, CUL3, CUL1, OGT, SEMA7A, IKBKG, IKBKAP, CAMK1, MAPKAPK5, CDC14B, MADD, PRKRA, TNFSF11, PDE5A, EIF3A, EIF3B, EIF3D, EIF3F, EIF3G, EIF3J, PEA15, CDC23, SERPINB7, TRADD, URI1, EED, RIPK1, CRADD, TNFSF14, TNFSF10, ADAM9, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10B, TNFRSF10A, IQGAP1, CFLAR, HDAC3, KAT2B, CDC123, CDC16, EIF2B4, EIF2B3, EIF2B2, EIF2B5, BCL10, CDK5R2, RPS6KA4, TNFSF18, HAP1, SOCS3, DIRAS3, USP14, RGN, LATS1, RQCD1, AIFM1, CCNE2, ARHGEF2, ZW10, BUB3, BMP15, VAPB, CRLF1, RPS6KA5, ITGB1BP1, GPR55, S1PR2, SOCS6, KLF4, TRIP12, CNOT8, TAOK2, SLIT2, SLC9A3R1, QKI, EIF2AK3, AKAP6, ATG5, PSMF1, GDF15, TMEM59, BAG5, BAG4, GMFG, CARTPT, TRAF4, EIF5B, KDM4A, RAPGEF2, PUM1, SLK, HDAC4, RASSF2, DLGAP5, IST1, RNF40, CTIF, SFI1, RB1CC1, RGP1, ZEB2, PPP1R26, PSMD6, NUAK1, OXSR1, TNFSF15, RBX1, KCNE2, CASP8AP2, ABI1, HDAC6, PDCD6, BCL2L10, BCL2L11, TOM1L1, RANBP9, CTDSP2, RAD50, FEM1B, FRY, TRAP1, AKAP9, RASA4, ATP6AP2, FARP1, SORBS3, TNK2, RNF41, PSME3, EIF1, CTDSPL, TRIB1, EIF1B, TNIP1, ABCA7, HMG20B, ANAPC10, PRG3, PIAS3, RAPGEF3, CD2BP2, ARIH2, ZER1, MAD2L2, EIF3M, CRTAP, STK25, ATG7, ARL6IP5, ARFGEF1, USP16, HEXIM1, RGS14, IGF2BP3, SPINT2, KHDRBS1, CTCF, NRG3, PTTG2, GIPC1, ZMYND11, ARPP19, SPINT3, FRS3, RUVBL2, ARID5A, USP19, MALT1, JTB, COPS8, PRDX3, ERP29, SPINK5, IL24, RBPMS, ADRM1, UBE2C, CDC37, GLMN, STRAP, MAP4K5, RASSF1, CHEK2, FZD10, AKAP13, STK38, PHB2 |
2034 | GO:0006826 | 0.05 | 1.90 | 13.77 | 19 | 33 | iron ion transport | ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, CLTC, DNM2, FTL, IREB2, SLC11A2, SLC11A1, PICALM, ATP6V0E1, ATP6V0D1, RAB11B, ATP6V1F, ATP6V1G1, HEPH |
2035 | GO:0019915 | 0.05 | 1.90 | 13.77 | 19 | 33 | lipid storage | ABCA1, APOA1, C3, CD36, SCARB1, CRP, CRY1, B4GALNT1, GM2A, HEXB, IL1B, ITGAV, ENPP1, STAT5B, NR1H2, NRIP1, DGAT1, ABCG1, EHD1 |
2036 | GO:0045071 | 0.05 | 1.90 | 13.77 | 19 | 33 | negative regulation of viral genome replication | ADAR, BST2, IFI16, IFIT1, ISG20, LTF, OAS1, OAS3, PARK2, EIF2AK2, PROX1, SLPI, SRPK2, OASL, VAPB, VAPA, TNIP1, IFITM3, IFITM2 |
2037 | GO:0051881 | 0.05 | 1.90 | 13.77 | 19 | 33 | regulation of mitochondrial membrane potential | ALOX12, BAD, BAX, BCL2, BCL2L1, TSPO, CCK, CDKN2A, DCN, IFI6, KDR, P2RX7, PARK2, PYCR1, SOD1, UBB, ARL6IP5, PRDX3, TUSC2 |
2038 | GO:1903391 | 0.05 | 1.90 | 13.77 | 19 | 33 | regulation of adherens junction organization | ACVRL1, ARHGAP6, COL16A1, EFNA5, EPHA3, GPM6B, HRG, KDR, SMAD3, PTPRJ, RAC1, RDX, S100A10, SDC4, SLC9A1, TSC1, VEGFA, ITGB1BP1, SLK |
2039 | GO:0006368 | 0.03 | 1.89 | 16.69 | 23 | 40 | transcription elongation from RNA polymerase II promoter | CCNH, CCNT1, CCNT2, CDK9, ERCC3, GTF2F1, SHH, SSRP1, SUPT4H1, TAF2, TAF4B, TAF5, TAF6, TAF13, TBP, IKBKAP, RNF8, CTDP1, RECQL5, IKZF1, ZMYND11, ADRM1, SUPT16H |
2040 | GO:1902531 | 0.00 | 1.89 | 229.36 | 312 | 559 | regulation of intracellular signal transduction | A2M, ABCA1, ADA, ADORA1, ADRA1B, ADRA2C, ADRB2, ALK, BIRC3, XIAP, APOA1, ARF6, ARHGAP4, ARHGAP5, ARHGAP6, ARHGDIB, ARHGDIG, ATP6AP1, ATR, BAD, BAX, BCL3, BID, BMP1, BMP6, BMP8B, BST2, BUB1, C3, C5, CAMK2A, CAMK2G, CASP10, CAT, CAV2, CBL, CD4, CD8A, CD36, CD40, CDK5, CDKN2A, CHN1, CHN2, CHUK, CCR1, CMKLR1, CNTF, COL3A1, CSF2, CSF2RB, CSPG4, CTF1, CTH, DDX5, DFNA5, DNM2, RCAN1, GPR183, ECM1, ECT2, EDA, LPAR1, EDN3, EDNRA, EFNA1, EPHA7, EPHA8, ERBB2, EREG, F2R, FGA, FGD1, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FGG, FGR, FLNA, FLT1, FLT3, FPR1, FYN, GDF9, GDI1, GDI2, GIP, GNAI1, GNAS, GRB2, GRIN2A, GRM1, HIC1, HPX, HRC, HES1, HTR2C, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGFBP3, IL2RA, IL2RB, IL2RG, IL13, IL18, INHA, IRAK2, ISL1, ITGA1, ITGAL, ITPKB, JUN, KDR, KISS1, KIT, KRAS, LTF, MARK3, KITLG, NRAS, NTF3, NTRK1, NTRK3, OCRL, TNFRSF11B, OPHN1, P2RX3, P2RX4, P2RY1, PEBP1, PDE4D, PDE6G, PDE6H, PDPK1, PF4, PIK3CB, PLN, PPP5C, PRKACA, PRKCB, PRKCE, PRKD1, PRKCQ, PRKCZ, RELN, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTGER4, PTPN13, PTPRA, RAC1, RAC2, RAC3, RAF1, RAP1A, RAP1GAP, RDX, RHEB, RPS27A, RYK, S100A4, S100A8, S100A9, S100A12, S100A13, S100B, CCL20, CCL22, CCL24, CCL25, XCL1, CX3CL1, SELP, SFPQ, SHC1, SIAH1, SIPA1, SLC9A1, SLC12A1, SLC20A1, SOD1, SOS1, SOS2, SOX2, SOX9, SOX11, SPTA1, SPTB, STYX, XCL2, TNFRSF1A, TNFRSF1B, TRIO, TSG101, TNFRSF4, UBB, UBE2V1, UBE3A, VAV1, WNT11, TRIM25, SHOC2, FGF23, OGT, SEMA7A, MADD, PRKRA, PDE5A, BECN1, PEA15, TRADD, TNFSF10, ADAM9, TNFRSF6B, TNFRSF18, TRIM24, IL18R1, CFLAR, ARHGEF7, BCL10, TNFSF18, KALRN, HAP1, RGN, DGKI, BMP15, VAPA, CRLF1, CYTH3, CYTH2, GPR55, S1PR2, TRIP10, ARHGAP29, EIF2AK3, ARHGEF6, PSMF1, GDF15, CARTPT, TTI1, RAPGEF2, PUM1, BCLAF1, ARHGEF17, FARP2, PSMD6, RHOBTB1, DENND4B, ARHGAP25, RBX1, BCL2L11, AKAP9, ATP6AP2, FARP1, SORBS3, PSME3, TRIB1, RCAN2, TRIM22, ABCA7, VAV3, TRIM38, ARFGEF2, SH2B2, HEXIM1, RBCK1, RRAGA, TRAF3IP2, FRS3, EDAR, SERINC3, ERP29, IL24, PIM2, RCAN3, AKAP13, PHB2 |
2041 | GO:0030316 | 0.02 | 1.89 | 19.61 | 27 | 47 | osteoclast differentiation | ACP5, ANXA2, APC, ATP6AP1, BGLAP, CA2, CAMK4, CHUK, CCR1, EPHA2, FSHR, GPC3, GNAS, IFNG, JUNB, LTF, KLF10, TYROBP, TNFSF11, INPP4B, GPR55, CARTPT, RASSF2, GAB2, FARP2, LRRC17, FSTL3 |
2042 | GO:0006901 | 0.01 | 1.89 | 22.54 | 31 | 54 | vesicle coating | AP2B1, AREG, ARF1, CD59, AP2S1, COPA, COPB1, CSNK1D, CTSZ, EPS15, GOLGA2, GRIA1, HIP1, LMAN1, PIK3C2A, PPP6C, RAB1A, TRAPPC10, PICALM, CUL3, USO1, COPB2, SEC22B, GOSR2, SNAP91, PREB, SEC24B, SEC23A, SEC24A, TMED10, COPE |
2043 | GO:0032990 | 0.00 | 1.89 | 274.18 | 370 | 657 | cell part morphogenesis | ABL2, ACTB, ACTG1, ADAM10, ADCY1, AP2A1, AP2B1, ANGPT1, APBB1, APC, ARHGAP4, RERE, ATOH1, BAX, BBS1, BBS2, BBS4, BCL2, BCL2L1, BMPR2, CACNA1A, CACNA1F, CACNA1S, CACNB4, CALM3, CAMK2A, CAMK2G, CCK, CD72, CDC42, CDK5, CHN1, CHRNB2, AP2M1, AP2S1, CLU, CLTA, CNP, COL2A1, COL3A1, COL4A3, COL4A4, COL4A5, COL5A1, COL5A2, COL6A2, COL6A3, COL9A1, COL9A3, CSF2, CSF2RB, CSNK1D, CSNK2A1, CSNK2A2, CTNNA2, CTNND2, CUX1, CYLD, DCC, DCX, DLG1, DLG3, DLX5, DNM1, DNAH5, DNM2, DPYSL3, HBEGF, ECM2, DUSP5, DUSP7, DUSP9, E2F4, EFNA1, EFNA3, EFNA4, EFNA5, EFNB2, CELSR2, EGR2, EPHA2, EMX1, CTTN, EPHA1, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, ERBB2, EREG, ETV1, ETV4, EXT1, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FLNA, FYN, GAP43, GATA3, GDI1, GDNF, GFRA1, GOLGA4, GPC1, GPM6A, GRB2, GRIN2A, ARHGAP35, NRG1, ONECUT1, HPRT1, HSPA8, HSP90AA1, HSP90AB1, IL2RA, IL2RB, IL2RG, ILK, ISL1, ITGA1, ITGA2, ITGA5, ITGA9, ITGAV, ITGB1, KIF5A, KIT, KRAS, LAMA5, ABLIM1, LIMK1, CAPRIN1, MAP6, MARK3, RAB8A, KITLG, SEPT2, SLC11A2, NRAS, NRCAM, NRTN, NTF3, NTF4, NTRK1, NTRK2, NTRK3, NTN3, OCRL, ODF2, OGN, OPHN1, OTX2, PEBP1, PARK2, PAX2, PCM1, ENPP2, PPP5C, PRKCQ, PRKCZ, MAPK3, PSPN, RELN, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPRA, PTPRD, PTPRM, PTPRZ1, RAB3A, RAC1, RAC2, RAF1, RAP2A, RASA2, RFX3, RFX4, RNF6, RPGR, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RRAS, RREB1, RYK, S100A6, S100B, SCN5A, SDC2, SDCBP, SEMA3F, SGK1, ITSN1, SHC1, SHH, SIAH1, SIAH2, STIL, SLIT1, SLIT3, SOS1, SOS2, SPAG1, SPAST, SPTA1, SPTB, SRF, AURKA, CDKL5, STK11, STXBP1, SUPV3L1, SYT1, SYT4, CNTN2, TBCE, DYNLT1, NR2E1, TNR, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, UGT8, VCL, VEGFA, VIL1, EZR, WEE1, XK, YWHAH, LRP8, SEMA3B, FZD3, FGF23, IFT88, RND2, USP9X, PICALM, CUL3, OFD1, SEMA7A, CNTNAP1, CDC14A, KLF7, UNC5C, NUMB, DYNLL1, PEA15, RAB11A, IQGAP1, NRP2, AKAP4, ARHGEF7, CPNE1, PHOX2B, WASF1, RPS6KA4, KALRN, HAP1, ATP6V0D1, DCLK1, RPS6KA5, NUMBL, SNAP29, SLIT2, CPNE6, NRXN3, NRXN1, ATG5, ONECUT2, PSMF1, AATK, FEZ2, IQCB1, RAPGEF2, RIMS2, SEMA3E, IFT140, KIAA0586, IST1, CUL7, FARP2, PSMD6, RBX1, ABI1, RANBP9, PQBP1, COL4A3BP, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, FARP1, WASF2, PSME3, COQ7, ABCC4, CCNO, SEMA3A, SPON2, OLFM1, VAV3, BAIAP2, SLC9A6, CAP2, CAP1, STK25, SEMA6C, SEMA6B, SEMA4F, SEMA4B, ATG7, ARPC1A, DPYSL4, PDLIM5, AVIL, TBR1, CHL1, SEPT9, FRS3, EHD1, VAX1, CIT, KIF3A, IL1RAPL1, TWF2 |
2044 | GO:1901564 | 0.03 | 1.89 | 16.45 | 23 | 42 | organonitrogen compound metabolic process | ACP5, ARSA, STS, ARSD, ARSE, ARSF, BAX, BTD, GIF, GRIN2A, HLCS, HPX, KIT, PCCA, PPP2R1A, SFTPB, SLC34A1, SLC22A5, SNCB, SRD5A1, CUBN, SNCAIP, CTRC |
2045 | GO:0048878 | 0.00 | 1.89 | 47.72 | 66 | 118 | chemical homeostasis | ADORA1, ANPEP, XIAP, TSPO, CCK, CNR1, COMT, CPS1, CRY1, CRY2, CYP11B1, CYP27B1, DBH, DCN, DHPS, EPB42, FECH, FGF7, IFI6, SLC37A4, GCGR, GJA5, GK, FFAR1, IDUA, IGFBP5, KCNA1, KCNJ10, KDR, SMAD7, OAS1, OTC, PARK2, PCK1, PDE3B, PDK4, PRCP, PTCH1, PTHLH, PTPN3, PYGL, RPS6, SCN2B, SCN5A, SCN10A, SFRP4, SFTPD, SLC2A4, SLC9A3, SLC9A5, SLC12A1, SLC16A1, SLC34A1, SOD2, STAT3, STK11, HNF1A, UPK3A, VEGFA, PICALM, TNFSF11, TRIM24, STXBP5L, HCN4, SLC9A6, CORIN |
2046 | GO:0034620 | 0.00 | 1.89 | 31.30 | 43 | 75 | cellular response to unfolded protein | AARS, ACADVL, ADD1, ASNA1, ASNS, ATF3, ATF4, BAX, CCND1, TPP1, CTH, DDX11, EIF2S1, EP300, ERN1, EXTL3, HDGF, IFNG, DNAJB9, PARK2, EIF2AK2, DNAJC3, PTPN1, SHC1, SSR1, SULT1A3, WFS1, ZBTB17, ATP6V0D1, VAPB, EIF2AK3, GOSR2, CUL7, BCL2L11, CTDSP2, PREB, PDIA6, CREB3, AGR2, SEC61B, PDIA5, KDELR3, SEC63 |
2047 | GO:0051172 | 0.00 | 1.88 | 33.30 | 46 | 82 | negative regulation of nitrogen compound metabolic process | ACP5, ADAR, AP2A1, ANG, ATF4, CIRBP, CLU, CLTC, COMT, DDX3X, EIF2S1, EIF4E, EIF4EBP1, EIF4EBP2, EPRS, GAPDH, GRB7, IGFBP5, IL10, EIF3E, IREB2, CAPRIN1, SMAD1, PRKAA1, EIF2AK2, RAN, RBM3, RBM4, SORL1, SRP9, TARBP2, TSC1, PRKRA, EIF2B4, EIF2B3, EIF2B5, HAP1, RQCD1, CNOT8, QKI, EIF2AK3, PUM1, ABCA7, PRG3, OLFM1, IGF2BP3 |
2048 | GO:0031327 | 0.03 | 1.88 | 16.63 | 23 | 41 | negative regulation of cellular biosynthetic process | ACADL, ACADVL, APLP1, CACNA1A, LPAR1, EDNRA, GALR1, GHSR, GNAI3, GRM8, INHA, INS, INSIG1, PRKAA1, PRKCA, SFTPD, AKR1C3, AKAP6, GABBR2, RAPGEF2, PRG4, ERLIN1, ERLIN2 |
2049 | GO:0006024 | 0.02 | 1.88 | 20.39 | 28 | 49 | glycosaminoglycan biosynthetic process | ANGPT1, VCAN, CSPG4, DCN, EXT1, EXT2, EXTL1, EXTL2, EXTL3, GPC4, GPC5, GPC3, GPC1, HEXA, IGF1, SDC1, SDC2, SDC4, UGDH, CHST3, HS2ST1, SDC3, HS3ST3B1, HS3ST3A1, HS3ST1, GPC6, CSPG5, B4GALT7 |
2050 | GO:0044802 | 0.00 | 1.87 | 185.85 | 252 | 447 | single-organism membrane organization | ABCA1, ABCA4, ADORA1, AREG, ARF1, ARF6, ASNA1, ATP1B3, BAD, BBS1, BBS2, BCL2, BCL2L1, BID, BNIP3L, BSG, CACNA1A, CALCR, CAMK2A, CASP8, CCNB1, CD59, CDH1, CDK5, AP2M1, CLU, CLTC, CNP, COL5A1, COPA, COPB1, ATF2, CSNK1D, CTSZ, DAB2, DLG2, DLG3, DNM2, DPP6, EPHA2, EMD, STOM, ERBB2, ETV5, EYA2, ACSL3, FAU, FCER1G, FLNA, FNTA, FYB, GAS6, GDI1, GDNF, GLRB, GOLGA2, GOLGA4, SFN, GRIA1, HK2, HSPA4, HSP90AA1, IFNG, INSIG1, ITGA3, ITGA4, ITGAL, ITGB1, JUP, KCNE1, KCNN4, KRT18, LAMA5, LMAN1, RPL10A, NRCAM, NUP88, NUP98, OXA1L, P2RX7, P2RY1, PDPK1, ATP8B1, PIGR, PPP2R1A, PPP2R2A, PPP3R1, PPP6C, PRKCA, PRKCB, PRKCI, PRKCZ, MAPK8, RELN, PTCH1, PTN, PTPRD, PEX19, PEX5, RAB1A, RAB13, RAC1, RANBP2, RAP2A, RDX, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, CLIP1, S100A9, SCP2, SDCBP, SLC9A1, SLC12A1, SNCA, SOD1, SPAG4, SPTA1, SPTB, SRP9, SRP14, SRP19, SRP68, SSR1, SSR3, STAT3, SYP, CNTN2, TAZ, TRAPPC10, TNFRSF1A, TSC2, TULP1, TULP2, TULP3, SUMO1, VIL1, EZR, VRK1, WRB, YWHAG, YWHAH, YWHAZ, NUP214, AAAS, MADCAM1, UBL4A, CUL3, OGT, BLZF1, SSNA1, NUMB, DYNLL1, RAB11A, BANF1, LIN7A, SYNJ1, AP3D1, RPL14, MAP7, SYT7, CCNB2, VAPB, VAPA, RAB11B, ITGB1BP1, COPB2, TAOK2, RPL23, SLC9A3R1, NRXN1, NRXN2, PEX16, CRIPT, PICK1, TMEM59, BAG4, GOSR2, NUP155, NUP93, RAPGEF2, SPCS2, TOMM20, BCL2L11, ATP9A, PREB, ARFRP1, RAMP2, RAMP3, TRDN, ABCA7, ATP8A1, SEC24B, ACAA2, BAIAP2, SEC23A, ATG7, AGR2, SIVA1, SORBS1, NUP50, SEC24A, SEC61B, TMED10, FERMT2, RAB31, RER1, NUPL2, IL1RAPL1, RPL35, SEC63, COPE |
2051 | GO:0034728 | 0.00 | 1.87 | 37.98 | 52 | 91 | nucleosome organization | ATRX, BRDT, CENPA, CENPI, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, H3F3B, HIST1H1A, HMGA1, RBBP4, SET, SMARCA4, SMARCC1, SMARCC2, SMARCD3, SMARCE1, SOX9, TSPY1, CHAF1B, HIST1H4I, HIST1H2BG, HIST1H2BL, HIST1H2BM, HIST1H2BF, HIST1H2BH, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HAT1, HIST1H3F, HIST1H2BJ, H1FX, RNF8, CTCF, SUPT16H, OIP5 |
2052 | GO:0051051 | 0.01 | 1.87 | 30.59 | 42 | 74 | negative regulation of transport | ADA, ANPEP, ANXA2, ARF6, ATF4, AVPR2, BCL2, BST2, CD74, COMT, CRYAB, ESR1, NRG1, ICAM1, INHA, INSIG1, KCNA5, OXT, ENPP1, PRKAA1, PRKCA, PRKCB, PRKD1, RAC1, SDCBP, SFRP4, STC1, STXBP3, SYT4, TACR2, UCN, VIP, FGF23, PICALM, VAMP8, PEA15, CD84, CARTPT, RUBCN, ACAA2, IL1RAPL1, CORO1A |
2053 | GO:0002698 | 0.02 | 1.87 | 20.43 | 28 | 49 | negative regulation of immune effector process | ANGPT1, ANXA1, APOA1, BST2, C1QBP, HLX, IFIT1, IFNA2, IGF2, IL2RA, IL10, INS, SERPINB9, PPM1B, EIF2AK2, PTPN6, RPS19, SERPINB4, XCL1, SEC14L1, SPN, TARBP2, TNFSF4, CD84, PGLYRP1, TNFSF18, TRIM38, SPINK5 |
2054 | GO:0051346 | 0.00 | 1.87 | 95.47 | 130 | 229 | negative regulation of hydrolase activity | A2M, SERPINA3, AHSG, AKT2, AMBP, ANXA1, APCS, BIRC3, XIAP, BIRC5, APLP2, APOA1, AQP1, RHOH, ARL2, SERPINC1, AVP, BBS4, BICD1, BST2, SERPING1, C3, C5, CASP8, SERPINH1, CD44, CDKN2D, COL4A3, COL6A3, CR1, CRY2, CRYAB, CSNK2A1, CST1, CST6, DDX3X, DHCR24, DLG2, DLG3, DPEP1, ECM1, SERPINB1, IFI6, GAS6, GPC3, GNAT1, SFN, GPS2, GPX1, SERPIND1, HGF, HPN, HRG, IFI16, IFIT1, ITIH1, ITIH2, ITIH3, ITIH4, KNG1, IPO5, PEBP1, SERPINE1, PAX2, SERPINA5, SERPINF1, PI3, SERPINB6, SERPINB8, SERPINB9, SERPINB10, SERPINI1, SERPINB13, PRKCZ, PROS1, PTPRN2, PZP, RAF1, RAG1, RDX, RGS2, RPS6KA1, RPS6KA3, SORT1, SERPINB3, SERPINB4, SIAH2, SLPI, SNCA, SORL1, SPINK1, SPINT1, SERPINA7, TRAF2, VEGFA, VIL1, VTN, PICALM, RECK, SERPINB7, TRADD, URI1, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, IQGAP1, CFLAR, AIP, USP14, DGKI, KLF4, SLIT2, PSMF1, BAG4, SFI1, PPP1R26, RASA4, FARP1, TNK2, CD2BP2, ARFGEF1, SPINT2, PTTG2, SPINT3, PRDX3, SPINK5, FICD, FZD10 |
2055 | GO:0072676 | 0.05 | 1.87 | 14.61 | 20 | 35 | lymphocyte migration | ADAM10, ECM1, S1PR1, GAS6, GATA3, GPR15, ITGA4, PIK3CG, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, STK10, XCL2, TNFSF14, CXCL14, CXCL13 |
2056 | GO:1903725 | 0.05 | 1.87 | 14.61 | 20 | 35 | regulation of phospholipid metabolic process | APOC2, ARF1, SCARB1, CDC42, EPHA8, ACSL3, FGFR3, FGR, FLT1, FLT3, HTR2C, IDH1, KIT, RAC1, CCL21, ZP3, PIK3R3, KLF4, RUBCN, VAV3 |
2057 | GO:0051224 | 0.00 | 1.87 | 44.65 | 61 | 107 | negative regulation of protein transport | ANGPT1, ANXA1, ANXA4, ANXA5, APOA1, BARD1, CD36, CDK5, CYLD, EMD, F2R, F2RL1, FBLN1, GAS6, GDI1, GHSR, HMGCR, IFNA2, IL1B, IL10, TNFRSF9, INS, KCNE1, KCNJ11, TONSL, PARK2, PDE4C, PPM1A, PPM1B, SRGN, PTGER4, REST, CX3CL1, SFRP5, SNAI2, SOX4, SP100, SREBF1, ABCC8, TRIP6, TNFSF4, TNFRSF4, EZR, VSNL1, AKAP1, DYRK2, OGT, TNFSF14, ITGB1BP1, SLC9A3R1, CABP1, STXBP5L, LITAF, BAG4, NR1H4, APC2, TACC3, CREB3, OS9, ERP29, WWP2 |
2058 | GO:0050770 | 0.00 | 1.86 | 35.89 | 49 | 86 | regulation of axonogenesis | ARHGAP4, BMPR2, CACNA1A, CDK5, CHN1, DCC, DNM2, EFNA1, EFNA5, CTTN, EPHA4, EPHA7, EPHB3, GDI1, GOLGA4, NRG1, ILK, LIMK1, NRCAM, NTRK2, NTRK3, RNF6, SEMA3F, SLIT1, SLIT3, SRF, CDKL5, STK11, CNTN2, TNR, VEGFA, XK, SEMA3B, RND2, SEMA7A, RAB11A, SLIT2, AATK, SEMA3E, IST1, SEMA3A, OLFM1, STK25, SEMA6C, SEMA6B, SEMA4F, SEMA4B, TBR1, TWF2 |
2059 | GO:1902578 | 0.00 | 1.85 | 661.56 | 861 | 1640 | single-organism localization | A2M, ABAT, ABCA1, ABCA2, ABCB7, ABCA4, ABL2, ACHE, ACO1, ACTB, ACTG1, ACTN1, ACVR2B, ADA, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADCYAP1R1, ADD1, ADD3, ADORA2A, ADRA2C, ADRB2, ADRBK1, ADRBK2, AP2A1, AP1G1, AGXT, AHSG, ABCD1, ALOX15B, ANG, ANPEP, SLC25A4, ANXA1, ANXA3, ANXA4, ANXA5, ANXA6, ANXA11, APOF, APBB1, APOA1, APOA4, APOC2, APOH, APRT, SHROOM2, AQP1, AQP5, AQP6, AQP7, ARF4, ARL4D, ARG1, ARL1, ATF4, ATP1A2, ATP12A, FXYD2, ATP2B1, ATP2B2, ATP4A, ATP4B, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, ATP5O, ATP7B, KIF1A, AVP, AVPR2, AXL, AZGP1, BARD1, CCND1, BCL2A1, HCN2, BDKRB2, BGLAP, BLK, BNIP3, SERPING1, C3, C5, VPS51, CA1, CA2, CA4, CA5A, CA6, CA7, CACNA1B, CACNA1E, CACNA1F, CACNA1S, CACNA2D1, CACNB4, CACNG1, SLC25A20, CALM3, CALU, CAMK4, CAMK2A, CAMK2G, CASP5, CASQ2, CCK, CD3G, CD9, CD14, SCARB1, CD38, CD40, CD58, CD63, CD74, CDH17, CDO1, CDX2, CEBPE, CETP, CFTR, AKR1C4, CHI3L1, CHKA, CHRM1, CHRM3, CHRNB2, CHRNB4, CHUK, AP1S1, CLCA1, CLCN2, CLCN3, CLCN5, CLCN6, CLCN7, CLCNKA, CLCNKB, CLU, CLNS1A, CLTA, CCR1, CCR5, CNGA1, CNGA2, CNP, CNR1, COMT, COX4I1, COX5B, COX6A1, COX6A2, COX6B1, COX7A1, COX7B, COX7C, COX8A, COX15, CP, CPT1B, CPT2, ATF2, CREBL2, CRP, CRY1, CRY2, CRYM, CSF2, SLC25A10, CTGF, CTNS, CTSS, CUX1, CXADR, CYBA, CYP27B1, CD55, ACE, DDC, DHODH, DIAPH1, DYNC1I2, TSC22D3, EDN3, EDNRA, EDNRB, EFNA5, CELSR2, EGR2, EIF2S1, EIF2S3, EIF4E, EIF5A, ENSA, SLC29A1, EPHA5, EPS15, ESR1, EYA2, F2RL1, F7, F10, FABP6, ACSL1, ACSL4, FBLN1, FCGR2A, FCGRT, FCN1, FCN2, FGA, FGF7, FGG, FOLR3, FTL, FYN, G6PC, SLC37A4, GABRA4, GABRB2, GABRE, GABRG1, GABRR1, GABRR2, GAD1, GAD2, GALR1, GAS1, GATA3, GCG, GCGR, GDF9, GDNF, GFAP, B4GALT1, GHRH, GHRHR, GHSR, GIF, GIP, GJA3, GJA4, GJA5, GJB1, GJB2, GPC3, GLE1, GLP1R, GLRA1, GLRA2, GLS, GLUD1, GLUL, GM2A, GNAS, GOLGA3, GOLGB1, GOT2, GPLD1, GPM6A, GPM6B, XCR1, GPR27, FFAR1, FFAR3, GRK6, GRB2, GRIA4, GRID1, GRID2, GRIK3, GRIN2A, GSTM2, GUCA1B, GUCA2B, GUK1, HAS2, HBA1, HBA2, HBM, HBD, HBG1, HBG2, HBQ1, HCK, HGF, HHEX, HMGCR, FOXA2, HPN, HPX, AGFG1, HRC, HRG, HRH2, HTR2C, HTR3A, ICAM1, IFNA2, IGF2, RBPJ, IL1A, IL1RN, TNFRSF9, INHA, INS, IREB2, ISL1, ITGA2, ITGAV, ITPR1, ITPR2, ITPR3, KCNA1, KCNA2, KCNA3, KCNA4, KCNA5, KCNA10, KCND2, KCND3, KCNJ2, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ12, KCNJ13, KCNJ14, KCNJ15, KCNJ16, KCNK2, KCNK3, KCNN1, KCNN4, KCNQ1, KCNS1, KCNS2, KCNS3, KIF5A, KISS1, KNG1, KLC1, LAMP2, LCAT, LIMK1, LTBP2, LTF, MFGE8, MYO1B, SEPT2, SLC11A2, NTF3, NTRK2, NTSR1, OAZ1, OAZ2, OSBP, OXCT1, OXT, P2RX3, P2RX4, P2RY2, P2RY4, P2RY6, PCSK6, PAEP, SERPINE1, PAM, PAWR, SERPINA5, PCM1, PCP4, PCSK1, PCSK5, CDK16, PDE3B, PDE4B, PDE4C, PDE4D, ENPP1, SLC26A4, PER1, PF4, ATP8B1, PFKFB2, PFN1, ABCB1, PIK3C2A, PIK3C3, PIK3CB, FXYD3, PLN, PPID, PPT1, PRKAA1, PRKAB2, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCB, PRKCE, PRKCG, PRKD1, PROC, PROS1, PRSS8, PTAFR, PTGER4, PTGS1, PTPN3, PTPN6, PTPN14, PTPRN, PTPRN2, ABCD3, RAB3B, RAB5C, RAF1, RALA, RAP1GAP, RARA, RCVRN, REST, RFX3, RHAG, RHCE, RHD, ABCE1, RPGR, RTN2, RXRA, RYR1, RYR2, RYR3, S100A1, SORT1, S100A6, S100A8, S100A9, S100A12, SCN1A, SCN2B, SCN3A, SCN4B, SCN5A, SCN8A, SCN10A, SCNN1A, SCNN1B, SCNN1D, SCNN1G, CCL21, XCL1, CX3CL1, SDC1, SDC4, SEC14L1, SEL1L, SELE, SELP, SEMG1, SFRP4, SRSF1, SRSF2, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SFTPD, SGK1, SLAMF1, SLC1A6, SLC1A7, SLC2A2, SLC2A3, SLC2A4, SLC2A5, SLC4A1, SLC5A2, SLC5A3, SLC5A5, SLC6A2, SLC6A4, SLC6A6, SLC6A7, SLC6A8, SLC6A11, SLC6A12, SLC6A13, SLC7A1, SLC7A4, SLC8A1, SLC8A3, SLC9A3, SLC9A5, SLC10A1, SLC10A2, SLC12A2, SLC12A3, SLC12A4, SLC13A1, SLC15A1, SLC15A2, SLC16A1, SLC34A1, SLC18A1, SLC20A1, SLC20A2, SLC25A1, SLCO1A2, SLC22A1, SLC22A3, SLC22A2, SLC22A5, SLN, SNTA1, SOD1, SOX4, SOX11, SP100, SPARC, SPAST, SPG7, SPINK1, SPTA1, SPTB, STAR, STAT5B, STC1, STXBP3, STYX, ABCC8, SURF1, SYT4, TAC1, TACR2, TAF7, CNTN2, SERPINA7, HNF1A, ICAM5, TMF1, TNFAIP2, TP73, TPD52, TPT1, TRAF2, TRH, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, TSC1, TSG101, TST, TUBA4A, TWIST1, TNFSF4, TNFRSF4, TYRO3, UBE3A, UCN, UCP1, UFD1L, NR1H2, UPK3A, UQCRC1, UQCRFS1, UQCRH, USF2, VAV1, VCL, VDAC2, VDR, VEGFA, VEGFB, VEGFC, VIP, TRPV1, VSNL1, WFS1, WRN, XK, SLC30A1, SLC30A2, ZP3, BSND, ALMS1, TUBA1A, PAX8, SCG2, ARHGEF5, TUSC3, STAM, CUBN, SLC25A16, CUL5, FGF23, AAAS, SLC7A5, SLC14A2, CLTCL1, SYN3, SLC10A3, PICALM, FZD4, SRPX, EEA1, LTBP4, NR0B2, SOAT2, PIK3R3, KCNAB2, CYP4F2, CAMK1, FCN3, TNFSF11, KCNK5, SLC4A4, STX16, STX10, PEA15, SRSF9, ABCC3, RIPK1, ADAM9, IQGAP1, NR1I2, PROZ, ARHGEF7, SLC5A6, EIF2S2, AP1S2, AP1M1, CDK5R2, ATP6V0E1, SLC25A14, SLC13A2, SYT7, RGN, ATP6V0D1, SEC22C, SLC16A6, SLC16A5, SLC16A4, SLC6A5, DGKI, COX7A2L, IL1RL1, AP4M1, RASSF9, SLC24A1, SLC16A7, KCNAB3, DCLK1, CYTH3, ATP6V1F, HMGN3, SLC22A6, RAB9A, NRXN3, SLC22A8, COX5A, COG1, LIPG, SLC22A14, SLC22A13, KCNK6, ABCG2, GSTO1, EIF2AK3, AKAP7, ATG5, SLC4A8, STXBP5L, GOSR1, RAB3D, ATP6V1G1, ATP5J2, VPS26A, NR1D1, CLOCK, CARTPT, ABCG1, SNCAIP, CLINT1, PUM1, RUBCN, USP6NL, GPRASP1, IFT140, SNX17, DHX38, SCRN1, RGP1, DNAJC6, HEPH, ELMO1, C2CD2L, OSBPL2, SMG7, SV2B, SGSM2, OXSR1, WDR1, GOLGA5, SLC23A2, NR1H4, DOPEY2, KCNE2, ABI1, KCNE3, HDAC6, PDCD6IP, HCN4, HMGXB4, TOM1, AP1M2, ABCC5, ABCB6, ABCC9, COX17, SCAMP2, ATP9A, COL4A3BP, ARPC5, ARPC4, ARPC3, ARPC1B, ARPC2, SGK2, ARL4C, AKAP9, WASF2, SLC25A13, SLC25A15, ALYREF, CALCRL, DDX39A, STX6, SLC35B1, KCNMB2, RABEPK, STAM2, ABCC4, SIGMAR1, TRDN, ABCA7, ABCA10, ABCA9, ABCA8, CACNG2, TUBA1B, RAPGEF3, SPON2, ACAA2, VAV3, BAIAP2, SLC30A9, COG5, ATP5H, SLC25A17, SLC9A6, NXF1, SEC23B, CAP1, FBLN5, ATG7, ARL6IP5, ARPC1A, SLC35A1, ARFGEF2, ARFGEF1, SLC34A2, SIVA1, SLCO1B1, TRIM16, ATP5L, EXOC5, DCTN6, TNFSF13B, EBP, CLDN16, CORIN, AP4B1, GIPC1, TRAF3IP2, NUP50, AHCYL1, SRSF10, ARPP19, STARD10, SLC26A1, SLC22A7, CFHR4, RNPS1, EHD1, SERINC3, ERP29, UQCR11, RAB32, SLC38A3, SLC27A5, SLC27A4, SLC27A2, IFT27, RAB35, SLC35D2, WWP1, WWP2, RAPGEF4, TMEM115, CACFD1, NUPL2, CAPN10, SLC7A9, CDC37, IL1RAPL1, GLMN, BVES, CORO1A, AP4S1, ABCB8, PRAF2, CA5B, HRH3, DCTN3, XPOT, DDX19B, SCN11A, SLCO2B1, TMC6, TUSC2, GABARAP |
2060 | GO:0007613 | 0.02 | 1.85 | 21.26 | 29 | 51 | memory | CHRNB2, CNR1, COMT, CX3CR1, DBH, EIF4EBP2, FEN1, GIP, GRIN2A, HRH1, HRH2, IGF1, IGF2, IL1B, ITGA3, ITGA5, ITPR3, KCNK2, OXT, SERPINF1, PTGS1, S100B, SLC6A4, SLC8A3, ITGA8, KAT2B, RIN1, RCAN2, ABCA7 |
2061 | GO:0031497 | 0.00 | 1.85 | 33.80 | 46 | 81 | chromatin assembly | ATRX, CDKN2A, CENPA, CENPI, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, H3F3B, HIST1H1A, HMGA1, RBBP4, SET, SOX9, TSPY1, CHAF1B, HIST1H4I, HIST1H2BG, HIST1H2BL, HIST1H2BM, HIST1H2BF, HIST1H2BH, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HAT1, HIST1H3F, HIST1H2BJ, H1FX, CTCF, BAZ2A, OIP5 |
2062 | GO:0032102 | 0.00 | 1.84 | 44.10 | 60 | 106 | negative regulation of response to external stimulus | ABAT, ALOX12, ANGPT2, ANXA2, ANXA5, APOH, BBS2, BBS4, PRDM1, TSPO, C1QBP, SERPING1, C5, CCK, CTNNA2, EPHA4, F12, FABP7, FAP, FGA, FGG, GCG, GP1BA, GRID2, HMGCR, HRG, IFIT1, KLKB1, KNG1, LTF, SERPINE1, PPM1B, PRKG1, EIF2AK2, PROS1, SEC14L1, SEMA3F, ST6GAL1, SNAI2, TARBP2, TNR, TSC1, UCN, USF1, VTN, SEMA3B, NRXN1, CARTPT, FEZ2, RUBCN, SEMA3E, TRIB1, SEMA3A, TRIM38, SEMA6C, SEMA6B, SEMA4F, SEMA4B, CXCL13, SPINK5 |
2063 | GO:1901700 | 0.03 | 1.84 | 16.57 | 23 | 43 | response to oxygen-containing compound | ACVR2B, ANGPT2, APOH, ATP1A2, DAGLA, CD9, COL6A2, ATF2, CTSV, DGKQ, ENSA, ERCC1, GLUL, GYS2, HLCS, P2RX3, PFKFB2, SELL, TRPC3, TRPM2, SLC14A2, NR0B2, GPR55 |
2064 | GO:0006892 | 0.01 | 1.84 | 27.96 | 38 | 67 | post-Golgi vesicle-mediated transport | AP2A1, AP1G1, ARF1, BBS1, BBS2, AP1S1, CLTA, CLTC, DNM2, EPS15, ACSL3, FTL, BLOC1S1, GOLGA4, HSPA8, KRT18, MYO1B, SORT1, SORL1, BLZF1, VAMP8, SNAP23, AP1S2, AP1M1, AP4M1, CLINT1, PUM1, DNAJC6, DOPEY2, AP1M2, SCAMP2, ARFRP1, ARFGEF2, EXOC5, AP4B1, VAMP5, RAB31, AP4S1 |
2065 | GO:0032272 | 0.05 | 1.84 | 15.44 | 21 | 37 | negative regulation of protein polymerization | ADD1, BBS4, CAPZA1, CAPZB, EPS8, PFN1, PFN2, RDX, SGK1, SNCA, SPTA1, SPTB, TBCD, TMOD1, VDAC2, VIL1, SLIT2, ARFGEF1, AVIL, STMN2, TWF2 |
2066 | GO:0001654 | 0.00 | 1.84 | 41.94 | 57 | 101 | eye development | ACHE, ACTL6A, ACVR2B, ACVRL1, APC, ATP2B1, BFSP1, BMP6, BMPR2, CACNA1F, CACNA1S, CDK4, CLCN2, CRX, CRYAB, CRYBA1, CRYBA4, CTNS, DLG1, FGF9, GATA3, GNB1, GPD2, GPM6A, ARHGAP35, HIF1A, IMPDH1, IMPDH2, JUN, LIM2, SMAD3, NTRK3, SERPINF1, RARA, RCN1, PRPH2, RPL24, RRM1, RXRA, SHH, SMARCA4, SMARCD3, SRF, NR2E1, TMOD1, TULP3, VIM, IFT88, FZD4, BFSP2, ALDH1A2, KLF4, IFT140, ZEB2, MAB21L2, VAX1, KERA |
2067 | GO:0048523 | 0.00 | 1.83 | 73.68 | 102 | 197 | negative regulation of cellular process | ACHE, ADRBK1, AP2A1, AP2B1, AMHR2, ARF1, BICD1, AP2S1, CLTA, CCR5, CTNND1, CYBA, DIAPH1, DNM1, EPHA2, ELF1, EPS15, FBN1, FCN1, GLRA1, GNAI1, GPC1, GPM6B, XCR1, GRB2, GRIA1, GRIK3, ONECUT1, HRC, HTR2C, IFIT1, IGFBP2, ISG20, ITPR1, ITPR2, ITPR3, LRPAP1, LTBP1, OAS1, OAS3, OVGP1, PPM1B, PPP1CA, PPP2CB, PRKCB, PTPRE, RASA2, RFNG, RFX4, RGS1, RGS10, RGS13, RGS16, RYR1, RYR2, RYR3, SEC14L1, SLAMF1, SLC8A1, SLC18A1, SRPK2, TRIP6, TRPC1, TULP3, TRIM25, PXDN, RAB7A, EPM2A, STAM, DYRK2, MAPKAPK5, OASL, PTCH2, RGS11, RGS9, DLK1, ARHGEF7, CPNE1, DGKI, VAPB, VAPA, DHRS3, S1PR2, ZFYVE9, CABP1, ONECUT2, LITAF, ADAMTSL2, GPRASP1, FIG4, RBX1, PDCD6, HMGXB4, IL18BP, G3BP1, RASA4, STAM2, TRAIP, TACC3, OLFM4, IFITM2, OS9 |
2068 | GO:0071804 | 0.00 | 1.83 | 47.99 | 65 | 115 | cellular potassium ion transport | AQP1, ATP1A2, ATP12A, ATP1B3, FXYD2, ATP4A, HCN2, CASQ2, CAV3, CNGA1, CNGA2, DNM2, DPP6, EDN3, HPN, HTR3A, KCNA1, KCNA2, KCNA3, KCNA4, KCNA5, KCNA10, KCND2, KCND3, KCNE1, KCNJ2, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ12, KCNJ13, KCNJ14, KCNJ15, KCNJ16, KCNK2, KCNK3, KCNN1, KCNN4, KCNQ1, KCNS1, KCNS2, KCNS3, REST, SLC12A4, ABCC8, SUMO1, KCNAB2, KCNK5, KCNAB3, KCNK6, AKAP7, AKAP6, OXSR1, KCNE2, KCNE3, HCN4, ABCC9, AKAP9, KCNMB2, RAPGEF3, WWP2 |
2069 | GO:0006875 | 0.01 | 1.83 | 30.87 | 42 | 75 | cellular metal ion homeostasis | ABCB7, ACO1, AGTR2, ALAS2, APLP2, ARF1, ATP12A, ATP1B3, ATP4A, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, BMP6, CP, FTL, HIF1A, HPX, IREB2, KCNJ2, LTF, NUBP1, SLC11A2, S100A8, S100A9, SGK1, SLC9A1, SLC11A1, SOD1, SLC30A2, AP3D1, ATP6V0E1, ATP6V0D1, ATP6V1F, ABCG2, ATP6V1G1, HEPH, ABCB6, SGK2, CLDN16 |
2070 | GO:0048562 | 0.00 | 1.83 | 48.74 | 66 | 117 | embryonic organ morphogenesis | ACVR1, ALX3, ATOH1, ATP2B2, ATP6V1B1, BBS4, BMP4, RUNX2, COL2A1, COL11A1, DLG1, DLX5, DLX6, EPHB2, EYA1, FGF3, FGF8, FGF9, GATA3, GATA4, GFI1, GNAS, HIF1A, HLX, HMX2, HOXC11, HOXD3, HOXD4, HOXD11, HPN, HES1, INSIG1, SMAD3, OTX1, OTX2, PRRX1, MAPK3, PTK7, RAC1, RPL38, RYR2, SALL1, SHH, STIL, SIX1, SOD1, SOX2, SOX9, SRF, TULP3, CLRN1, WNT1, ZIC1, PAX8, FZD3, FZD6, ITGA8, PRKRA, HESX1, SLC9A3R1, HAND1, HAND2, IRX5, SEC24B, SIX2, GJB6 |
2071 | GO:0060562 | 0.01 | 1.82 | 26.52 | 36 | 64 | epithelial tube morphogenesis | ACVR1, ACVRL1, AREG, BAX, CAV3, CTSZ, EDNRA, EPHA2, ESR1, ETV4, ETV5, GATA4, B4GALT1, HHEX, FOXA2, TNC, IGF1, RBPJ, IHH, KDR, KRAS, SMAD3, PGR, PPP1CA, PRKX, PTHLH, RYR2, SLC12A2, SOX2, SRF, VDR, WNT2, SLIT2, HAND2, SEMA3E, PHB2 |
2072 | GO:0035335 | 0.01 | 1.82 | 28.80 | 39 | 69 | peptidyl-tyrosine dephosphorylation | ACP1, CDC25C, DUSP1, DUSP4, DUSP5, DUSP7, DUSP9, EYA4, EYA1, EYA2, EYA3, PTPN1, PTPN3, PTPN4, PTPN6, PTPN7, PTPN12, PTPN13, PTPN14, PTPRA, PTPRB, PTPRD, PTPRE, PTPRH, PTPRJ, PTPRM, PTPRN2, PTPRR, PTPRZ1, TPTE, PTP4A1, EPM2A, CDC14B, CDC14A, RNGTT, DNAJC6, PTPRU, PTPN21, DUSP12 |
2073 | GO:0044093 | 0.00 | 1.82 | 330.40 | 439 | 804 | positive regulation of molecular function | ACVR2B, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADCYAP1R1, ADORA2A, ADRB2, ADRBK1, AGTR2, AKT2, ALDH1A1, ALDOB, ALOX12, AMPH, ANG, ANGPT1, APOA1, APOA4, APOC2, APOH, ARF1, ARF4, ARHGAP4, ARHGAP5, ARHGAP6, ARHGDIB, ARHGDIG, ARL1, AVPR1B, AVPR2, BAD, BAX, CCND1, BCL2, BID, BMI1, BNIP2, BOK, C5, CALCR, CAMK4, CAMK2G, CASP8, CASP9, CAV2, CCK, CCNB1, CCNC, CCND3, CCNH, CCNT1, CCNT2, CD4, CD14, SCARB1, CD74, CDC6, CDC20, CDC27, CDC42, CDH3, CDKN1A, CDKN2A, CENPE, RCBTB2, CHI3L1, CHN1, CHN2, CLPS, COL4A3, CR1, CSF2, CSF2RB, CSPG4, CTGF, CYP27B1, ACE, GADD45A, DDX3X, DHFR, DLG1, HBEGF, DUSP5, DUSP7, DUSP9, ECT2, S1PR1, LPAR1, EDN2, EDN3, EDNRA, EEF1A2, EFNA1, EFNA5, EIF2B1, EPHA2, EMP2, EPHA1, EPHA4, EPHA8, ERBB2, ERCC6, ERN1, F2R, F3, ACSL1, FBLN1, FCER1A, FCER2, FGD1, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FGR, FLT1, FLT3, FNTA, FPR1, FSHR, FYN, GAS6, GCGR, GDI1, GDI2, GDNF, GHRHR, GLP1R, GM2A, GNA15, GNAL, GNAQ, GNAS, GNAT1, GPLD1, FFAR1, GRB2, RAPGEF1, GRIN2A, ARHGAP35, GRM1, CXCL1, GTF2F1, GUCA1A, GUCA1B, GUCA2A, GUCA2B, HGF, NRG1, HIF1A, HIP1, AGFG1, AGFG2, IFI16, IFNG, IGFBP3, IL2RA, IL2RB, IL2RG, ILK, ITGA6, ITGA1, ITGB1, ITPR1, ITPR2, ITPR3, JUN, LLGL2, SMAD3, MARK3, MAP3K5, KITLG, MGST2, MAP3K11, PPP1R12A, PPP1R12B, SLC11A2, NRAS, NTF3, NTRK2, NTRK3, NVL, OCRL, OPHN1, P2RX7, P2RY11, PEBP1, PAWR, PCOLCE, PDE6G, PDE6H, PDE1B, PDPK1, PFKFB2, PFN1, PFN2, PIK3CB, PIM1, PIK3CG, PPP5C, PRKAA1, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCG, MAPK3, MAPK8, PROX1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN1, PTPRA, RAB3A, RAB4A, RABIF, RAC1, RAF1, RAP1A, RAP1GAP, RAP1GDS1, RASA2, RCVRN, REST, RFC1, RGS1, RGS2, RGS10, RGS13, RGS16, RPGR, RPS2, RSU1, SBF1, SERPINB3, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SELE, SEMG1, SETMAR, SFTPB, ITSN1, SHC1, STIL, SIPA1, SKP1, SLC11A1, SNCA, SOD1, SORL1, SOS1, SOS2, SPTB, CDKL5, STK10, STK11, XCL2, SYK, TBCD, TNNT2, TP73, TPD52L1, TRIO, TSC1, TSC2, UBE2D1, UBE2L3, UCN, NR1H2, VAV1, VDR, VIP, VIPR2, WFS1, WNT11, WRN, XRCC4, ZNF16, ZP3, FZD5, FGF23, PICALM, FZD8, BCAR3, NSMAF, CUL3, CUL1, OGT, CAMK1, MAPKAPK5, CDC14B, MADD, PRKRA, PDE5A, TNKS, PEA15, CDC23, S1PR4, CRADD, TNFSF10, ADAM9, RGS11, RGS9, TNFRSF10B, TNFRSF10A, IQGAP1, ASAP2, CDC16, EIF2B4, EIF2B3, EIF2B2, EIF2B5, HERC2, CDK5R2, KALRN, RQCD1, AIFM1, RABEP1, AURKB, VAPB, CYTH3, CYTH2, ITGB1BP1, GPR55, S1PR2, TRIP10, GTF3C4, TAOK2, ARHGAP29, ARHGEF6, PSMF1, STXBP5L, GMFG, CARTPT, RIN1, GUCA1C, USP6NL, ACAP1, SLK, RASSF2, RAPGEF5, RGP1, ARHGEF17, ZEB2, EPM2AIP1, FARP2, PSMD6, SGSM2, DENND4B, RABGAP1L, ARHGAP25, OXSR1, TNFSF15, RBX1, CASP8AP2, ABI1, PDCD6, BCL2L10, BCL2L11, TOM1L1, SH2D3C, SH2D3A, UBA2, RAD50, RASA4, FARP1, PSME3, RASGRP2, DENND4A, ABCA7, ANAPC10, CDC42EP2, VAV3, CAP2, CAP1, CREB3, STK25, ARL6IP5, CXCL13, ARFGEF2, ARFGEF1, CCT4, CCT2, CDC42EP3, RGS14, NRG3, FRS3, JTB, COPS8, DBF4, ERP29, ADAP1, ADRM1, UBE2C, RAPGEF4, CDC42EP1, MAP4K5, FZD10, AKAP13, DUSP12 |
2074 | GO:0021987 | 0.03 | 1.82 | 19.18 | 26 | 46 | cerebral cortex development | ATOH1, BAD, BAX, BBS2, BBS4, CDK5, COL3A1, CX3CR1, DCX, HIF1A, NTRK2, RELN, RAC1, SOX2, SRD5A1, TACC1, NR2E1, TSC1, LRP8, CUL5, CDK5R2, SLIT2, SEMA3A, TACC3, ATG7, TACC2 |
2075 | GO:0055080 | 0.00 | 1.82 | 49.40 | 67 | 120 | cation homeostasis | ABCB7, ACO1, ADORA1, AGTR2, ALAS2, ANPEP, XIAP, APLP2, ARF1, ATP12A, ATP1B3, ATP4A, ATP6V1A, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, AVPR2, BMP6, CA2, CA7, CFTR, CLCN3, CLN5, COMT, CP, EPB42, FECH, FTL, HIF1A, HPX, IREB2, KCNJ2, KCNJ10, LTF, NUBP1, SLC11A2, OTC, PDK4, SLC26A4, PPT1, PTGER4, RHAG, SCNN1A, SCNN1B, SCNN1G, SGK1, SLC9A1, SLC9A3, SLC9A5, SOD1, UPK3A, RAB7A, PICALM, CYP4F2, ATP6V0E1, ATP6V0D1, ATP6V1F, ABCG2, ATP6V1G1, HEPH, ABCB6, SGK2, SLC9A6, CLDN16, CORIN, SLC26A1 |
2076 | GO:0051091 | 0.03 | 1.82 | 19.90 | 27 | 48 | positive regulation of sequence-specific DNA binding transcription factor activity | ANXA3, CEBPG, ATF2, EP300, EPHA5, ESR1, IL10, JUP, KIT, DDR2, RELN, SHH, SMARCA4, SP100, SRF, VEGFA, WNT1, WNT2, ZIC2, LRP8, ARHGEF5, FOSL1, FZD4, BUD31, HDAC4, RNF41, PHB2 |
2077 | GO:0021549 | 0.03 | 1.82 | 19.20 | 26 | 46 | cerebellum development | AARS, ABAT, ABL2, AGTR2, RERE, ATP2B2, CACNA1A, CDK5, LPAR1, GRID2, OGDH, PROX1, PTN, RFX4, SCN5A, SSTR2, SSTR3, NR2C2, WNT1, USP9X, FZD4, ATRN, CDK5R2, HAP1, NRXN1, ATG7 |
2078 | GO:0033365 | 0.00 | 1.82 | 218.68 | 292 | 524 | protein localization to organelle | ACTL6A, ADAR, AGTR2, ANGPT1, ARF4, ARF6, ARL1, ARL2, ARNTL, ASNA1, RERE, ATR, ATRX, BAD, BAX, BBS1, BBS2, BBS4, BCL2, BCL3, BICD1, BID, BMP4, BMP6, BMPR1A, BNIP3L, BRCA1, BRCA2, BUB1B, TSPO, CASP8, CBLB, CD36, SCARB2, CDH1, CDKN1A, CDKN2A, CENPA, COL1A1, CSNK1D, CSNK2A2, CTSK, CYLD, DAB2, DDX1, DDX3X, DHX9, DIAPH1, ECT2, EDA, EMD, F2R, FAU, FGF9, FLNA, NR5A1, FYB, FYN, GAS6, KAT2A, GFER, GNAQ, GOLGA1, GOLGA4, SFN, GPR26, HIST1H1B, HCLS1, NRG1, HHEX, HK2, HES1, HSPA4, HSPA8, HSPA9, HSP90AA1, HSP90AB1, IFNG, IGF1, IL1B, IL10, IL18, INS, ITGAX, JUN, JUP, KPNA1, KPNB1, KPNA4, KPNA5, TNPO1, IPO5, SMAD3, RPL10A, TONSL, NRAS, YBX1, NUP88, NUP98, OGG1, OR1D2, PARK2, PCM1, PEX1, PEX6, PEX10, PEX12, PEX14, PPM1A, PPM1B, PPP3R1, SRGN, PRKCQ, MAPK3, MAPK8, PSMB7, PSMD8, PEX19, PEX5, RAB6A, RAC2, RAN, RANBP2, RB1, RDX, RNASE2, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, RYR2, SFRP5, SHH, STIL, SIX1, SIX3, SLC9A1, SLC11A1, SNAI2, SUMO3, SORL1, SOX9, SREBF1, SRP9, SRP14, SRP19, SRP68, SSR1, SSR3, STAT3, AURKA, STK11, SYK, TNFAIP3, CCT3, TRIP6, TRPS1, TSC2, TULP1, TULP2, TULP3, U2AF1, UBE2L3, SUMO1, VEGFA, EZR, WRB, YWHAG, YWHAH, YWHAZ, ZIC1, ZBTB17, FZD5, RAB7A, NUP214, CSRP3, AKAP1, UBL4A, BAP1, FZD7, DYRK2, OGT, AP3B1, AKR1C3, DYNLL1, TNKS, BECN1, TNFSF14, RAB11A, IL18R1, HDAC3, AP3D1, RPL14, AIP, ZW10, AURKB, VAPA, TRIP11, RPL23, SLC9A3R1, ZFYVE9, PEX16, CRIPT, EIF2AK3, AKAP6, CABP1, LITAF, BAG4, NUP155, IPO13, NUP93, CROCC, CEP57, IFT140, ZFYVE16, SPCS2, TOMM20, KIAA0753, SUPT7L, FAM20B, BCL2L11, PARP3, ARFRP1, TRIM28, NUTF2, APC2, ABCA7, ARIH2, TOMM40, TACC3, CREB3, CHERP, CCT7, CCT4, CCT2, RBCK1, TXNIP, CCT8, SIX2, RUVBL2, EDAR, EHD1, KDELR1, SEC61B, TOMM34, OS9, KDELR3, RAB35, RBPMS, RPL35, SEC63, SNF8, PHB2 |
2079 | GO:0031344 | 0.00 | 1.82 | 38.36 | 52 | 93 | regulation of cell projection organization | ADCY6, ARHGAP4, CACNA1A, CDC20, CDK5, CHN1, CHRNB2, DBN1, DCC, EFNA1, CTTN, EPHA7, EPHB3, GAK, GATA3, GDI1, GFAP, GFI1, GRID2, NRCAM, PRRX1, KLK6, RAP2A, RNF6, SDC2, SEMA3F, SLIT1, SLIT3, SNAP25, CNTN2, NR2E1, TNR, VIM, XK, YWHAH, SEMA3B, KLF4, BAG5, AATK, SEMA3E, KIAA0319, PQBP1, SEMA3A, OLFM1, CARM1, SEMA6C, SEMA6B, SEMA4F, SEMA4B, PDLIM5, TBR1, CIT |
2080 | GO:0061387 | 0.01 | 1.82 | 25.87 | 35 | 62 | regulation of extent of cell growth | ARHGAP4, BMPR2, CDK5, DCC, DNM2, EFNA5, CTTN, EPHA7, GOLGA4, NRG1, ILK, LIMK1, NRCAM, NTRK3, RNF6, SEMA3F, SRF, CDKL5, TNR, VEGFA, SEMA3B, RND2, SEMA7A, RAB11A, SLIT2, AATK, SEMA3E, IST1, SEMA3A, OLFM1, SEMA6C, SEMA6B, SEMA4F, SEMA4B, TWF2 |
2081 | GO:0044283 | 0.00 | 1.82 | 71.03 | 96 | 172 | small molecule biosynthetic process | ABAT, ACADL, ACADM, ACADVL, ACAT1, AGXT, ALDH1A3, ALDH9A1, ALOX12, ALOX15B, ANXA1, APOC2, ASL, ASNS, ASPA, ASS1, AVP, BCAT1, BCAT2, BHMT, BRCA1, CBS, CCBL1, CD74, CDO1, AKR1C4, CPS1, VCAN, CSPG4, CTH, CYP8B1, DCN, DHFR, DHPS, DPYD, EDN2, FCER1A, FGFR4, GAD1, GAMT, GGT7, GLS, GLUD1, GLUD2, GLUL, GPT, HMGCL, HPGD, HSD17B4, IDO1, LDHC, FADS3, LTA4H, MGST2, OAT, OTC, PAH, PDK4, PRKAB2, PROX1, PSPH, PTGIS, PTGS1, ABCD3, PYCR1, ALDH18A1, RBP1, RNPEP, ACSM3, SHMT1, SHMT2, ELOVL4, STK11, SYK, UGDH, UGP2, NR1H2, UROS, ACOX2, BBOX1, ALDH4A1, SUCLA2, ALDH1A2, KYNU, FADS2, QKI, NR1H4, ACOT8, DHRS9, COQ7, PRG3, CSPG5, FAXDC2, SLC27A5, SLC27A2, ACOT7 |
2082 | GO:0030509 | 0.01 | 1.82 | 32.55 | 44 | 78 | BMP signaling pathway | ACVR1, ACVR2A, ACVR2B, ACVRL1, XIAP, BMP1, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, RUNX2, DLX5, ETV2, FBN1, FGF8, FOXD1, GATA4, GATA6, GDF9, GPC3, HES1, RBPJ, ILK, ITGA3, SMAD1, SMAD6, SMAD7, PCSK6, PPM1A, MAPK3, RYR2, SOX11, T, UBE2D1, WNT1, ZNF8, USP9X, USP9Y, CHRD, BMP15, CER1, ZFYVE16, FSTL3 |
2083 | GO:0006402 | 0.00 | 1.81 | 56.34 | 76 | 135 | mRNA catabolic process | ATM, ZFP36L2, DDX6, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4G1, ERN1, FAU, EIF3E, RPL10A, CNOT2, CNOT4, EXOSC9, PPP2R1A, PPP2R2A, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, SUPV3L1, ZFP36, CSDE1, PRPF18, KHSRP, RPL14, RQCD1, CNOT8, RPL23, GTPBP1, DHX34, CTIF, SMG7, PAN2, RNPS1, RPL35, EXOSC8 |
2084 | GO:0016482 | 0.00 | 1.81 | 141.34 | 190 | 344 | cytoplasmic transport | ADRB2, AP2A1, AP1G1, AREG, ARF4, ARL1, BBS1, BBS2, BGLAP, BID, TSPO, VPS51, SCARB2, CD59, CD63, CDX2, AP1S1, CLTC, COPA, COPB1, CSNK1D, CTSZ, CD55, DYNC1H1, DYNC1I1, DYNC1I2, DNM2, EMP2, EPS15, F7, F10, FAU, GFER, GOLGA1, GOLGA2, GOLGA4, GOLGB1, XCR1, GRIA1, HSPA4, HSPA8, HSP90AA1, HTR2C, INS, ITPR1, ITPR2, ITPR3, KRT18, LMAN1, RPL10A, PEX1, PEX6, PEX10, PEX12, PEX14, PIK3C3, PPP6C, PROC, PROS1, PEX19, PEX5, RAB1A, RAB6A, RAB13, RAB5C, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS29, RYR3, SORT1, CCL21, SLC8A3, SPAST, SPTA1, SPTB, SRP9, SRP14, SRP19, SRP68, SSR1, SSR3, TRAPPC10, TRPM2, TSG101, TST, TRPV1, RAB7A, CLTCL1, EEA1, CUL3, AP3B1, BLZF1, USO1, DYNLL1, STX16, STX10, BECN1, RAB11A, PROZ, AP1M1, AP3D1, RPL14, AIP, SEC22C, AP4M1, ZW10, VAPB, VAPA, RAB11B, COPB2, TRIP11, RAB9A, COG1, PEX16, GOSR1, SEC22B, VPS26A, GOSR2, USP6NL, GPRASP1, ZFYVE16, SNX17, SPCS2, TOMM20, RGP1, SGSM2, DOPEY2, HMGXB4, ACTR2, PREB, ARFRP1, STX6, TOMM40, COG5, SEC23B, SEC23A, ARFGEF2, DCTN6, VAMP5, SEC24A, KDELR1, TOMM34, TMED10, RAB32, RAB35, RAB31, TMEM115, RPL35, SEC63, DCTN3, SNF8, COPE |
2085 | GO:0010508 | 0.05 | 1.81 | 16.28 | 22 | 39 | positive regulation of autophagy | ADRB2, BAD, BNIP3, BNIP3L, DCN, HIF1A, IFNG, KDR, PAFAH1B2, PIK3CB, PIP4K2A, PRKAA1, STK11, UVRAG, EPM2A, BECN1, ATG5, TMEM59, TRIM22, ATG7, SPTLC1, PIM2 |
2086 | GO:0043407 | 0.05 | 1.81 | 16.28 | 22 | 39 | negative regulation of MAP kinase activity | BMP4, CAV3, DUSP1, DUSP4, DUSP5, DUSP7, DUSP9, GPS2, HMGCR, IL1B, PPP2R1A, PRKCA, PTPN1, PTPN6, PTPRJ, RGS2, SERPINB3, SMPD1, SORL1, TP73, RGS14, STK38 |
2087 | GO:0021510 | 0.02 | 1.81 | 22.95 | 31 | 55 | spinal cord development | ACTL6A, PHOX2A, CACNA1A, DCC, EVX1, GLRA2, HOXC10, ISL1, PROX1, RELN, PTCH1, PTN, RFX4, RNF2, SHH, SOX1, SOX4, SOX11, SOX12, SRD5A1, TAL1, TULP3, WNT1, ZIC1, IFT88, CHRD, EED, SLIT2, BAG3, OLIG2, RAPGEF3 |
2088 | GO:0000902 | 0.00 | 1.81 | 237.95 | 317 | 577 | cell morphogenesis | ABL2, ACTB, ACTG1, ACTN1, ADAM10, ADCY1, ADD1, AP2A1, AP2B1, ANGPT1, APBB1, APC, RERE, ATOH1, ATP2B2, AXL, BBS1, BBS2, BCL2, BMP4, CACNA1F, CACNA1S, CACNB4, CALM3, CAMK2A, CAMK2G, CASP9, CCK, CD72, AP2M1, AP2S1, CLU, CLTA, CNP, COL2A1, COL3A1, COL4A3, COL4A4, COL4A5, COL5A1, COL5A2, COL6A2, COL6A3, COL9A1, COL9A3, CLDN3, CRYGB, CSF2, CSF2RB, CSNK1D, CSNK2A1, CSNK2A2, CTNNA2, CTNND2, DCX, DLG3, DLX5, DNM1, DNAH5, DPYSL3, HBEGF, ECM2, DUSP5, DUSP7, DUSP9, E2F4, ECT2, EFNA3, EFNA4, EFNB2, CELSR2, EGR2, EPHA2, EMX1, EP300, EPHA1, EPHA5, EPHA8, EPHB1, EPHB2, ERBB2, EREG, ERG, ETV1, ETV4, EXT1, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, GAP43, GATA3, GFRA1, GP1BA, GPC1, GPM6A, GRB2, GRIN2A, HGF, HIF1A, ONECUT1, HPRT1, HRH2, HES1, HSPA8, HSP90AA1, HSP90AB1, IDUA, RBPJ, IHH, IL2RA, IL2RB, IL2RG, ISL1, ITGA1, ITGA2, ITGA4, ITGA5, ITGA9, ITGAV, ITGB1, KIF5A, KRAS, LAMA5, ABLIM1, LIPA, MAP6, MARK3, RAB8A, KITLG, SEPT2, SLC11A2, NRAS, NRTN, NTF3, NTF4, NTRK1, NTN3, OCRL, OGN, OPHN1, OTX2, P2RX7, PEBP1, PCM1, PPP5C, PRKCQ, PRKCZ, MAPK3, PSPN, PROX1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN6, PTPRA, PTPRM, RAB1A, RAB3A, RAC2, RAF1, RASA2, RB1, RFX3, RFX4, RPGR, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RRAS, RYK, S100A4, S100A6, SCN5A, ITSN1, SHC1, SHH, SIAH1, SIAH2, STIL, SNAI2, SOD1, SOS1, SOS2, SOX9, SPAG1, SPAST, SPTB, ST14, STC1, AURKA, STXBP1, TAL1, TBCE, DYNLT1, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TYRO3, TYROBP, UBB, UGT8, UPK3A, CLRN1, VCL, VDR, WEE1, WNT2, WNT11, FZD3, FGF23, USP9X, PICALM, EOMES, FZD4, FZD7, CUL3, OFD1, CNTNAP1, ITGA8, CDC14A, KLF7, UNC5C, NUMB, DYNLL1, PEA15, ADAM15, IQGAP1, NRP2, AKAP4, CPNE1, PHOX2B, WASF1, RPS6KA4, KALRN, LATS1, ATP6V0D1, ARHGEF2, DCLK1, RPS6KA5, SNAP29, NRXN3, NRXN1, ONECUT2, PSMF1, FEZ2, IQCB1, KIAA0586, FARP2, PSMD6, RBX1, ABI1, RANBP9, COL4A3BP, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, FRY, AKAP9, TRIM28, RASA4, FARP1, WASF2, PSME3, ABCC4, CCNO, KLF2, SPON2, SEC24B, VAV3, SLC9A6, CAP2, CAP1, ATG7, ARPC1A, DPYSL4, SPINT2, AVIL, SIX2, CHL1, FRS3, EHD1, VAX1, KIF3A |
2089 | GO:0006631 | 0.00 | 1.81 | 78.88 | 106 | 189 | fatty acid metabolic process | ACAA1, ACADL, ACADM, ACADS, ACADSB, ACADVL, ACLY, ACOX1, AKT2, ABCD1, ALOX12, ALOX15B, ANXA1, APOA1, APOA4, APOC2, AVP, BRCA1, C3, DAGLA, CD74, CNR1, CPT1B, CPT2, CYP1A2, CYP2A6, CYP2A13, CYP2F1, DECR1, DLD, DPEP1, ECH1, EDN2, EHHADH, ETFA, ETFDH, FAAH, ACSL1, ACSL3, ACSL4, FCER1A, GGT7, GHSR, GK, GPX1, HADHA, HPGD, HSD17B4, INS, INSIG1, IVD, LIPA, LIPE, FADS3, LTA4H, MGST2, PAM, PCCA, PDK4, PRKAA1, PRKAB2, PRKAR2B, MAPK3, PTGIS, PTGS1, ABCD3, RNPEP, ACSM3, SCP2, SNCA, SREBF1, STAT5B, ELOVL4, STK11, SYK, TNFRSF1A, TWIST1, TYRP1, NR1H2, PDHX, ACOX2, ACOX3, CYP4F2, AKR1C3, SGPL1, CH25H, RGN, FADS2, QKI, EIF2AK3, ACOT8, PRG3, ACAA2, ECI2, SLC25A17, ERLIN1, PDPN, FAXDC2, ACOT2, SLC27A5, SLC27A4, SLC27A2, RPP14, ERLIN2, LYPLA2, ACOT7 |
2090 | GO:0048675 | 0.03 | 1.80 | 20.01 | 27 | 48 | axon extension | ARHGAP4, CDK5, DCX, DNM2, CTTN, ITGB1, NRCAM, RNF6, SEMA3F, SLIT1, SLIT3, TNR, VCL, SEMA3B, USP9X, NRP2, DCLK1, SLIT2, AATK, SEMA3E, SEMA3A, OLFM1, SLC9A6, SEMA6C, SEMA6B, SEMA4F, SEMA4B |
2091 | GO:0019752 | 0.00 | 1.80 | 58.33 | 79 | 144 | carboxylic acid metabolic process | ALB, ALDOB, ALDOC, ARNT, BPGM, BSG, BTD, C3, DAGLA, CYP1A2, CYP2A6, CYP2A13, CYP2F1, CYB5R3, ENO2, FABP6, ACSL1, ACSL4, GAPDH, GHSR, GK, GPD1, GPX1, HIF1A, HK2, HLCS, IGF1, LDHA, LIPA, P2RX7, PAM, ATP8B1, PFKFB2, PFKFB4, PGAM2, PGD, PGK1, PGK2, PGM1, PPP2R5D, PRKAR2B, PRKCE, MAPK3, RXRA, ST6GAL1, SLC2A3, SLC10A1, SLC10A2, SLC16A1, SLCO1A2, SLC22A5, SNCA, SREBF1, STAT3, TNFRSF1A, TYRP1, UGT2B4, UGT2B7, UGT8, SLC25A16, PDHX, OGT, ABCC3, VNN2, VNN1, SGPL1, SLC5A6, EIF2AK3, HDAC4, SLC23A2, GNE, ACAA2, SLCO1B1, PDPN, UGT2A1, ACOT2, RPP14, LYPLA2, ECD |
2092 | GO:0008037 | 0.01 | 1.80 | 30.46 | 41 | 73 | cell recognition | CD5, CD6, CD36, SCARB1, CLGN, CNR1, VCAN, DLG1, EPHA3, EPHA4, EPHB1, EPHB2, EPHB3, FCN1, FCN2, GAP43, B4GALT1, HIST1H1T, LAMA5, MFGE8, CD200, NRCAM, OPCML, OVGP1, PTPRZ1, PVR, CCL21, SPAM1, CNTN2, TNP2, CCT3, TULP1, ZAN, ZP2, ZP3, FCN3, SEMA3A, CCT7, CCT4, CCT2, CCT8 |
2093 | GO:0060429 | 0.00 | 1.79 | 65.13 | 88 | 161 | epithelium development | ABL2, ACAT1, AGTR2, ALDH1A3, AQP1, ARG2, BBS4, CA2, CASP8, CAT, CD44, COL5A1, CTSZ, DLG1, DLG3, HBEGF, EDNRA, EFNB2, CELSR2, EN1, EPHA4, EPHA7, GPC4, FGF1, FOXD1, GJA4, GJA5, GPC3, GRB2, ARHGAP35, GRSF1, HGF, HOXD11, TNC, IL10, ILK, ITGA5, KRAS, LLGL2, TACSTD2, EPCAM, SMAD1, SMAD6, SMAD7, OPA1, PBX1, PFN1, PGF, PPP1CA, PRKACB, PSPN, RALA, RYK, RYR2, SCNN1B, SDC4, STIL, SLC8A1, SNAI2, SPINT1, SRF, TSC1, TSC2, TULP3, TWIST1, VCL, VEGFC, WNT2B, ZIC2, FZD5, DCHS1, CHRD, ALDH1A2, BCL10, SOCS3, CRLF1, CER1, HAND1, HAND2, SEMA3E, IFT140, GPC6, TRIM28, ATP6AP2, COQ7, CITED2, SEMA3A, GLMN |
2094 | GO:0051649 | 0.00 | 1.79 | 354.96 | 469 | 884 | establishment of localization in cell | ABCA2, ACTL6A, ADAR, ADCYAP1R1, ADRB2, AP2A1, AP2B1, AKT2, ABCD1, ANXA2, BIRC5, ARF4, ARL1, ATM, RERE, ATP1A2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, ATP7B, KIF1A, BARD1, BBS1, BCL2L1, BCL3, BGLAP, BICD1, BMP4, BMPR1A, BNIP3, BNIP3L, BRCA1, BRCA2, BSG, BST2, TSPO, VPS51, CACNG1, SLC25A20, CAMK4, CASQ2, CBLB, CCNB1, CD4, SCARB2, CD74, CDC42, CDH1, CDKN1A, CDKN2A, CDX2, CENPA, CENPE, CENPF, CHRM1, AP2M1, AP1S1, AP2S1, CLTA, CLTC, CCR5, CNP, CPT1B, CPT2, ATF2, CRYAB, CSNK2A2, SLC25A10, CTSK, CUX1, CYBA, CYLD, DAB2, CD55, DIAPH1, DLG1, DYNC1H1, DYNC1I2, ECT2, EDA, EDNRA, EGR2, EIF4E, EIF5A, EMD, EMP2, CTTN, STOM, EPS15, ERBB2, EYA1, EYA2, F7, F10, ACSL3, FAU, FGF9, FTL, FYB, GAS1, KAT2A, GDI1, GEM, GFER, GLE1, GNAQ, GOLGA1, GOLGA3, GOLGA4, GOLGB1, GPM6B, XCR1, GPR26, GSTM2, HCLS1, NRG1, HHEX, HK2, AGFG1, HRC, HES1, HSPA4, HSPA9, HSP90AA1, HSP90AB1, IFIT1, IL18, INSIG1, ITGAX, ITGB1, JUN, JUP, KCNE1, KCNJ10, KIF5A, KLC1, KPNA1, KPNB1, KPNA4, KPNA5, TNPO1, IPO5, KRT18, SMAD3, MYO1B, CITED1, PPP1R12A, RPL10A, TONSL, NUMA1, NUP88, NUP98, OAZ1, OAZ2, OGG1, OPA1, OR1D2, P2RX3, P2RX4, PCM1, CHMP1A, PDE4D, PEX1, PEX6, PEX10, PEX12, PEX14, PLN, PPM1A, PPM1B, PRKAB2, PRKCI, PRKD1, MAPK3, PROC, PSMB7, PSMD8, PTCH1, PTPN1, PTPN6, PTPN14, PEX19, PEX5, RAB6A, RAB5C, RAN, RANBP2, RB1, RBM4, RDX, RNASE2, RPGR, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, CLIP1, RTN2, RYR1, RYR2, RYR3, SORT1, SCP2, CCL21, XCL1, SEL1L, SET, SFRP5, SRSF1, SRSF2, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SHH, SIX3, SLC6A4, SLC8A1, SLC8A3, SLC9A1, SLC11A1, SLIT1, SLN, SNAI2, SORL1, SP100, SPAST, SPG7, SPTA1, SPTB, SRP9, SRP14, SRP19, SRP68, SSR1, SSR3, STAR, STAT3, STYX, DYNLT1, TNNC1, TNNT2, TRIP6, TRPC1, TRPC3, TRPS1, TSC1, TSC2, TST, U2AF1, UBB, UBE2L3, UCP1, UFD1L, UVRAG, WRN, ZIC1, ZBTB17, ZP2, ALMS1, TUBA1A, FZD5, NUP214, AAAS, ANP32A, AKAP1, CLTCL1, PICALM, BAP1, FZD7, UXT, EEA1, DYRK2, OGT, CDC42BPA, CAMK1, BLZF1, SSNA1, AKR1C3, STX16, STX10, BECN1, SRSF9, CDC23, TNFSF14, IL18R1, INPP4B, HDAC3, PROZ, AP1S2, AP1M1, HERC2, SLC25A14, RPL14, AIP, SEC22C, AP4M1, ARHGEF2, RASSF9, ZW10, DCLK1, VAPB, VAPA, CYTH3, ITGB1BP1, TRIP11, TAOK2, RPL23, SLC9A3R1, ZFYVE9, COG1, PEX16, GSTO1, PICK1, AKAP6, CABP1, LITAF, BAG4, ATP5J2, VPS26A, ABCG1, NUP155, IPO13, CLINT1, NUP93, PUM1, CEP57, USP6NL, GPRASP1, IFT140, ZFYVE16, SNX17, DHX38, DLGAP5, TOMM20, RGP1, DNAJC6, C2CD5, SMG7, SGSM2, FAM20B, GOLGA5, DOPEY2, HDAC6, PDCD6, TOM1L1, HMGXB4, TOM1, SCAMP2, ATP9A, COL4A3BP, ACTR2, ARL4C, ARFRP1, TRIM28, SLC25A13, SLC25A15, ALYREF, NUTF2, DDX39A, STX6, STAM2, RAMP2, RAMP3, APC2, KATNB1, TRDN, TUBA1B, ATP8A1, ARIH2, ACAA2, TOMM40, TACC3, COG5, ATP5H, NXF1, SEC23B, CREB3, STK25, APPBP2, CHERP, SIVA1, RBCK1, TXNIP, ATP5L, RGS14, KHDRBS1, DCTN6, CSPG5, AP4B1, SIX2, NUP50, AHCYL1, SRSF10, VAMP5, MALT1, EDAR, RNPS1, EHD1, KDELR1, SEC61B, TOMM34, OS9, RAB32, IFT27, RAB35, RBPMS, TMEM115, RER1, NUPL2, ZWINT, CDC37, BVES, AP4S1, AKAP13, RPL35, SEC63, DCTN3, XPOT, DDX19B, PHB2, GABARAP |
2095 | GO:0051304 | 0.02 | 1.79 | 23.79 | 32 | 57 | chromosome separation | APC, ATM, BUB1, BUB1B, CCNB1, CDC6, CDC20, CDC27, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, ERCC4, MAD2L1, PPP2R1A, RB1, TOP2A, UBE2D1, ZNF207, CUL3, CDC23, CDC16, ZW10, BUB3, RECQL5, DLGAP5, ANAPC10, MAD2L2, PTTG2, UBE2C, CIT |
2096 | GO:0051054 | 0.03 | 1.79 | 20.81 | 28 | 50 | positive regulation of DNA metabolic process | ANXA3, APBB1, BAX, BRCA1, CD28, CD40, CEBPG, ERCC1, EYA1, EYA3, FGFR4, HGF, IFNG, MGMT, PRKCG, RAD51, RPS3, SETMAR, TOP2A, TNFSF4, UNG, WHSC1, TNFSF13, RNF8, BRE, PARP3, RAD50, TRIM28 |
2097 | GO:0016043 | 0.00 | 1.79 | 55.15 | 76 | 151 | cellular component organization | ACVR1B, AGTR2, ALOX12, APLP2, ARHGAP5, FXYD2, BCL3, BTG1, CD38, CDKN1A, CDKN2C, CDKN2D, CISH, CLCN6, COMP, VCAN, CYP27B1, ELF3, EXTL3, GDF9, B4GALT1, ICAM2, ICAM4, IGFBP2, IGFBP3, IGFBP5, IGFBP6, ITGAD, ITGAE, ITGAM, LAMA4, LTBP1, LTBP2, MATN3, MFAP3, TNFRSF11B, ENPP1, VIT, PIK3CB, EXOSC9, PPIB, PRKCG, RAB3B, SLC6A12, SLC12A4, SPINT1, TRO, VAV1, PXDN, LTBP4, RECK, TNK1, URI1, WISP3, WISP1, CLDN6, AKAP6, EI24, SDC3, ADAMTSL2, SNX17, SERTAD2, SGK2, TNK2, RASGRP2, CREB3, CRTAP, PRDX4, CGREF1, SPINK5, CCDC85B, STON1, OGFR, ESM1, EMILIN1, B4GALT7 |
2098 | GO:0019216 | 0.01 | 1.79 | 31.99 | 43 | 77 | regulation of lipid metabolic process | SERPINA3, ACADL, ACADVL, ADORA1, BBS4, BRCA1, TSPO, C3, CCNC, CNR1, CYP27B1, DHCR7, DLD, ESR1, FGFR4, NR5A1, GFI1, GK, FOXA2, INSIG1, PDE3B, PDK4, PIK3CG, PRKAB2, PROX1, REST, SNAI2, SNAI1, SNCA, SOD1, STAR, STAT5B, STK11, VDR, PDHX, IRS4, AKR1C3, EDF1, EIF2AK3, NR1H4, NR1D2, ERLIN1, ERLIN2 |
2099 | GO:0006520 | 0.02 | 1.79 | 22.98 | 31 | 56 | cellular amino acid metabolic process | AARS, ACADSB, ACAT1, ACY1, ALDH9A1, ATF4, BCKDHA, CACNA1A, SLC25A10, CTNS, DARS, DDC, EPRS, GARS, GSS, HSD17B10, HARS, PEPD, QARS, SLC6A6, SLC7A4, SUOX, TARS, TST, AIMP2, SLC7A5, BBOX1, SLC25A15, BCKDK, ATG7, FARS2 |
2100 | GO:0034655 | 0.00 | 1.79 | 76.91 | 103 | 185 | nucleobase-containing compound catabolic process | ATM, BAX, ZFP36L2, CDA, CDKN2A, DDX6, DFFA, DFFB, DNASE1L1, DNASE1L2, DNASE1L3, DNASE2, DPYD, TYMP, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4G1, ERN1, FAU, FEN1, EIF3E, ISG20, KPNA1, KPNB1, RPL10A, CNOT2, CNOT4, OAS2, EXOSC9, PPP1R8, PPP2R1A, PPP2R2A, RNASE2, RNASE3, RNASE6, ABCE1, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, SETMAR, SUPV3L1, ZFP36, CSDE1, PRPF18, KHSRP, RNASET2, RPL14, RGN, RQCD1, AIFM1, CNOT8, RPL23, GTPBP1, DHX34, CTIF, SMG7, PAN2, RNASEH2A, ERN2, RNPS1, RPL35, EXOSC8 |
2101 | GO:0098779 | 0.01 | 1.79 | 31.30 | 42 | 75 | mitophagy in response to mitochondrial depolarization | ADRB2, ANXA5, C5, CA7, CAPS, COX8A, EIF2S1, STOM, FANCC, FCGR3B, SLC37A4, BLOC1S1, HK2, KCNK3, KRT15, MDH1, NTHL1, PARK2, PGK2, SERPINB10, PRKG1, SFRP4, SLCO1A2, SLC22A3, SNRPD1, SNRPF, STAT2, NR2C2, ZNF189, CHAF1B, BECN1, CHST3, NUP93, RIMS3, PHYHIP, IST1, FGFBP1, HDAC6, CSPG5, HSF2BP, CDC37, ADAMTS7 |
2102 | GO:0048666 | 0.00 | 1.78 | 92.19 | 124 | 228 | neuron development | ADCY6, ALK, APOA1, APOA4, AREG, ARF1, ARF4, ARF6, BBS4, PRDM1, BMP4, TSPO, CALU, CDC20, CDH1, CLU, CLN5, CNR1, CNTF, CTF1, CTNNA1, DBN1, DHFR, LPAR1, EDNRB, EMX1, EN1, ACSL4, EFEMP1, GABRB2, GAK, BLOC1S1, GFAP, GFI1, GNAQ, GNAT1, GNAT2, GNGT1, GPM6A, RAPGEF1, GRID2, GRN, HGF, PRMT1, TNC, IHH, ITGA3, JUN, SEPT2, NRL, NTF4, OGDH, OPA1, OPCML, P2RY2, PARK2, PCP4, CDK16, SERPINF1, ATP8B1, PRRX1, PPT1, PRKCI, PRKD1, PRKCZ, PRKG1, KLK6, PTK7, PTN, RAB13, RAC3, RAP1A, RPGR, RXRA, SDC4, SNAP25, SOX1, SOX3, AURKA, STRN, SYT1, SYT4, DYNLT1, TP73, TULP1, UCN, UGT8, VIM, WEE1, WNT1, IFT88, SF3A2, CUL4B, CAMK1, BECN1, IQGAP1, KAT2B, CPNE1, CBFA2T2, VAPA, KLF4, NREP, CPNE6, PICK1, HAND2, CHST3, ONECUT2, ADAMTS1, BAG5, RIMS2, IFT140, KIAA0319, FIG4, NR2E3, TSPAN2, FRY, IRX5, KATNB1, CARM1, ARFGEF1, AVIL, EHD1, RAB35, STMN2 |
2103 | GO:0032435 | 0.03 | 1.78 | 20.87 | 28 | 50 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | APC, ATM, BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DUSP1, HSP90AB1, MAD2L1, SDCBP, SHH, SMARCC1, UBE2D1, ZNF207, CDC23, CDC16, USP14, ZW10, BUB3, BAG5, ANAPC10, MAD2L2, GIPC1, UBE2C |
2104 | GO:0032675 | 0.03 | 1.78 | 20.87 | 28 | 50 | regulation of interleukin-6 production | BPI, CD36, CYBA, EREG, F2R, F2RL1, FCER1G, GAS6, GHSR, IFNG, IL1B, IL10, ISL1, P2RX7, PAEP, PTAFR, SLAMF1, TNFAIP3, TWIST1, TNFSF4, UCN, TNFSF9, RIPK2, IL1RL2, ARHGEF2, PRG4, KLF2, SPON2 |
2105 | GO:0016477 | 0.00 | 1.78 | 47.36 | 64 | 118 | cell migration | ANG, SHROOM2, ARF4, RERE, BTG1, CD151, COL5A1, CTGF, CTNNA2, EMX2, ENPEP, EPHA3, EPHB1, EPHB3, ERG, FGFR4, FUT8, HES1, ITGA7, JUP, LAMA3, LAMA4, OGDH, PIK3C2A, PIK3C2B, PRKCI, PRKCQ, PRKCZ, PSG2, PTK7, RAB1A, SAA4, SCNN1B, SDC1, SDC2, SGK1, SIX3, SLC9A1, SRMS, TNR, TYK2, TYRO3, CUL5, USP9Y, CUL3, FOXN1, SORBS2, CDC42BPA, UNC5C, PSTPIP2, PSTPIP1, TAOK2, CDC42BPB, SDC3, SLK, ELMO1, GAB2, GPC6, ARPC5, TSPAN1, ABI2, TNK2, APC2, SIX2 |
2106 | GO:0009894 | 0.00 | 1.78 | 68.67 | 92 | 166 | regulation of catabolic process | ABL2, ACTL6A, ADORA1, ADRA1B, ADRB2, AKT2, APOA1, APOA4, APOC2, APOH, ARNT, BAD, BAX, BCL2, BCL2L1, BNIP3, BNIP3L, BPGM, ZFP36L2, TSPO, SCARB1, CNR1, CTSK, DCN, DFFA, EEF1A2, CTTN, ERN1, FAP, GATA4, KAT2A, GFAP, GOLGA2, GPD1, HGF, HIF1A, HP, IDH1, IFI16, IGF1, ITGB1, KDR, KIF25, P2RX7, PAFAH1B2, PDE3B, PGAM2, PIK3CB, PIK3CG, PIP4K2A, PPP1CA, PRKAA1, PRKCE, PTPN1, RPL28, SNCA, SNRNP70, SREBF1, STAT3, STK11, SUPV3L1, TSC1, TWIST1, U2AF1, UVRAG, ZFP36, ZBTB17, FZD5, EPM2A, IFT88, OGT, BECN1, AIFM1, CNOT8, RAB33A, ATG5, TMEM59, GTPBP1, FEZ2, KDM4A, DHX34, RUBCN, HDAC4, RB1CC1, HDAC6, TRIM22, RAPGEF3, SPTLC1, RRAGA, PIM2, WDR6, ECD |
2107 | GO:0051782 | 0.02 | 1.78 | 24.62 | 33 | 59 | negative regulation of cell division | APC, ATM, ATRX, BMP4, BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DUSP1, FGFR3, MAD2L1, PRKAR1A, PTCH1, RAD1, RPS6KA2, UBE2D1, ZNF207, TNKS, CDC23, CDC16, ZW10, BUB3, AURKB, TOM1L1, ANAPC10, MAD2L2, TXNIP, PTTG2, UBE2C |
2108 | GO:0044763 | 0.00 | 1.78 | 218.54 | 288 | 732 | single-organism cellular process | ABO, ACTA2, ACY1, ALDH3A1, ALDH9A1, AMT, ANPEP, APCS, ARG1, ARG2, PHOX2A, ART1, ASCL2, ASL, ASPA, ASS1, ALDH7A1, AUH, BCAT2, BCKDHA, BFSP1, BHMT, BTD, BYSL, C1QC, CA1, CA4, CA5A, CA6, RUNX1T1, SERPINH1, CCIN, CCBL1, CDH7, CDH9, CDH10, CDH12, CDH15, CDO1, CD52, CDX1, CDX4, CEBPE, CHD2, TBCB, CKM, CLN5, CLNS1A, CRX, CRYGB, CRYM, CSRP2, CYLC1, CYP8B1, DAO, DARS, DAZ1, DDC, DDX1, DDX6, DHX9, COCH, DHCR7, CYB5R3, DLX3, DLX6, SARDH, DNASE1L2, EEF2, EIF2B1, ELAVL1, ELAVL3, ELF3, EN1, EPB42, EPRS, EYA4, ESD, ETS2, ETV3, ETV6, EVX1, EXTL1, EXTL2, FANCE, FLG, FLI1, FLNC, FUT6, GABPA, GALK1, GALNS, GALNT1, GIF, GLUD2, GOLGB1, GOT2, GPT, GSS, GSTM1, GSTZ1, HAL, HAS3, HLF, HMGN1, HMX2, HOXC10, HOXD4, HOXD11, HPD, HSBP1, DNAJB2, ICAM4, IDS, FOXK2, IREB2, STT3A, IVL, KRT4, KRT5, KRT84, LIM2, LUM, MATN3, CHST6, MEA1, MEIS1, MFAP3, MGAT2, MGAT5, NRL, OAT, ODC1, ODF1, OMD, OTC, P4HA1, PAH, REG3A, PEPD, CFP, VIT, EXOSC9, PPIB, PPL, PPP1R7, PSPH, PTBP1, PURA, ALDH18A1, QARS, QDPR, REV3L, SRSF4, SGCB, SGCD, SGTA, SHMT2, SMARCA1, SMARCA2, SMS, SUMO3, SOX3, SOX5, SOX12, SPIB, SPINT1, SPRR1B, SPRR2A, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3, SRY, SSRP1, ST14, SUOX, TAF4B, TAGLN, TARS, TAT, TRO, TSPY1, TST, TTC3, TUBA3C, UBE2V2, UFD1L, UGDH, UGT2B4, UPK2, UPK3A, USH2A, VBP1, XRCC4, ZNF91, VEZF1, RNF103, SHFM1, CUBN, TAGLN2, BBOX1, PARG, DDO, PIR, PDXK, DDX3Y, ALDH4A1, GALNT4, B4GALT3, B3GALT2, EDF1, RIOK3, SCEL, SAP30, GGH, PROM1, EIF2B3, HERC2, P4HA2, USP13, CLDN12, CLDN6, KRT75, DYRK1B, DDX21, ZMYM6, GTF3C5, B4GALT6, B4GALT5, GRHPR, COG1, CIAO1, RECQL4, HAND1, ADAMTS2, CHD1L, FAM65B, SERTAD2, SPATA2, ZBTB24, XYLB, HS3ST4, HS3ST3B1, PTBP3, TRIM28, AASS, ALYREF, LRRC17, GLYAT, IRX5, SPEG, BCKDK, MARCH6, B3GNT3, HMG20A, KLF2, SPON1, ARIH2, PPIE, GPNMB, COG5, CRTAP, ENOX2, CIB2, DEAF1, RNASEH2A, SCGN, RAD51AP1, KLF1, FARS2, FUT9, ALDH1L1, DHRS4, UGT2A1, ASCC3, COPS6, SDS, CCDC85B, TMEM115, KERA, EMILIN1, SOX21, CA5B, TREX1, B4GALT7, CTRC |
2109 | GO:0051640 | 0.00 | 1.77 | 102.08 | 136 | 245 | organelle localization | ACTN4, ALB, AMPH, BIRC5, SHROOM2, AREG, ARF1, ATM, ATP2A1, ATP6AP1, BBS2, BBS4, BRCA2, CACNA1A, CAV3, CCNB1, CD59, CDH3, CDK5, CENPA, CENPE, CENPF, COPA, COPB1, CSNK1D, CTSZ, DLG1, DNM1, DYNC1H1, DNM2, EYA1, FCER1A, FCER1G, FGR, KAT2A, GEM, GOLGA2, GRIA1, GRN, HHEX, IL13, ITGA4, KIT, KPNB1, LLGL2, LMAN1, LRMP, MAP6, NUBP1, NUMA1, NUP88, OPHN1, P2RX7, PARK2, PCM1, CHMP1A, PDPK1, PEX1, PFN2, PIK3CG, SEPT5, PPP6C, RAB3A, RAB27A, RAB27B, RAC2, RAN, RAP1A, RB1, S100A13, ITSN1, SLIT1, SNAP25, SNCA, AURKA, STK11, STXBP1, STXBP2, SYK, SYN1, SYT1, TACC1, DYNLT1, TRAPPC10, UVRAG, EZR, LAT2, YWHAZ, DOC2A, CUL3, OGT, CDC42BPA, IKBKG, USO1, CADPS, VAMP8, STX11, BECN1, CDC23, RAB11A, SNAP23, LIN7A, CD84, SYNJ1, ARHGEF2, ZW10, RAB11B, COPB2, SNAP29, SLC9A3R1, NRXN1, GOSR1, SEC22B, GOSR2, CROCC, RIMS2, SNPH, RIMS3, DLGAP5, GAB2, HDAC6, AP1M2, ACTR2, PREB, KATNB1, SEC24B, TACC3, SEC23A, STK25, UNC13B, TACC2, SEC24A, CPLX2, CPLX1, TMED10, COPE |
2110 | GO:0060255 | 0.00 | 1.77 | 484.13 | 625 | 1207 | regulation of macromolecule metabolic process | A2M, SERPINA3, AARS, ABL2, ACHE, ACO1, ACTA2, ACTB, ADAR, ADARB1, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADK, ADORA1, ADRA2C, AHSG, ALOX12, AMBP, ANG, ANGPT1, ANPEP, ANXA2, APC, APCS, BIRC3, APLP2, APOA1, APOA4, AQP1, AREG, ARF1, ARR3, SERPINC1, ATM, ATP6AP1, ATR, AVP, AVPR2, BAD, BAX, BBS2, BBS4, BCL2, BDKRB2, BID, BOK, BST2, BUB1, BUB1B, TSPO, SERPING1, C3, C5, C8B, CALM3, CAMK2G, CASP8, CASP9, CAV2, CAV3, CBLB, SERPINH1, CCK, CCND3, CD4, CD14, TNFRSF8, CD44, CD59, CD63, CD74, CDC20, CDC25C, CDC27, CDC42, CDH3, CDK4, CDK6, CDKN1A, CDKN2C, CDKN2D, CENPE, CHAD, CHI3L1, CIRBP, CISH, CKS1B, CCR1, CNTF, COL2A1, COL4A3, COL6A3, CPA3, CR1, CRP, CRYAB, CRYBA1, CSF2, CSF2RB, CSNK1D, CSPG4, CST1, CST6, CTF1, CTGF, CTSG, CTSZ, CYP1A2, CD55, DAZ1, ACE, GADD45A, DDX6, DHX9, DFFA, DHCR24, DIO2, DLG2, DLG3, DPEP1, HBEGF, DUSP1, DUSP4, DUSP5, DUSP7, DUSP9, GPR183, ECT2, LPAR1, EDN3, EDNRA, EEF1A2, EEF2, EFNA5, EIF2S1, EIF2B1, EPHA2, EIF4A1, EIF4B, EIF4E, EIF4EBP1, EIF4EBP2, EIF4G1, EIF4G2, EIF5, EIF5A, SERPINB1, ELAVL1, EMP2, ENPEP, ENSA, EPHA1, EPHA4, EPHA7, EPHA8, EPHB1, EPRS, ERCC1, ERCC4, F3, F12, ACSL1, FAP, FBLN1, FCER1A, FCER2, FECH, FGA, FGF3, FGF6, FGFR4, FGG, FGR, FLOT2, FLT1, FLT3, FLT3LG, FLT4, FNTA, FPR1, FSHR, FUT8, FYN, IFI6, G6PC, GAPDH, GAS1, GFAP, GHRHR, GHSR, GNAQ, GNAS, GOLGA2, SFN, GP1BA, GPLD1, GPX1, GRB2, GRB7, RAPGEF1, GRIN2A, GRM1, SERPIND1, UBE2K, HMGCR, HPX, HRC, HRG, DNAJB2, HSPB1, HSP90AA1, HSP90AB1, HTR2C, TNC, IDE, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGFBP3, IGFBP5, IL2RA, IL2RB, IL2RG, IL13, IL18, INHA, INPPL1, EIF3E, IREB2, ITGA1, ITGA2, ITGA5, ITGAV, ITGB1, ITIH1, ITIH2, ITIH3, ITIH4, ITPKB, KCNK2, KCNQ1, KDR, KISS1, KLKB1, KNG1, KPNA1, TNPO1, LIMK1, CAPRIN1, MAD2L1, MARK3, CD46, MAP3K5, KITLG, MGMT, MAP3K11, SLC11A2, NRAS, NTRK2, NUP88, NUP98, NVL, OAZ1, OAZ2, ODC1, TNFRSF11B, OPHN1, PEBP1, PDCL, SERPINA5, PCOLCE, PCP4, PDE4D, PDE6G, PDE6H, ENPP2, SERPINF1, CFP, PFN2, PGGT1B, PI3, SERPINB6, SERPINB8, SERPINB9, SERPINB10, SERPINI1, SERPINB13, PIK3CB, PIK3CG, EXOSC9, PPP1R1A, PPP1R2, PPP1R7, PPP2CB, PPP2R1B, PPP2R2A, PPP2R5D, PPP4C, PPP5C, PRG2, PRKAB2, PRKACA, PRKACB, PRKACG, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCE, PRKCG, DNAJC3, PROS1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN1, PTPN3, PTPN6, PTPRA, PTPRJ, PTPRR, PTPRZ1, PZP, RAB1A, RAB27A, RAC1, RAC2, RAD51, RAG1, RAG2, RANBP2, RAP1A, RAP2A, RAP2B, RASA2, RBBP6, RBM3, RDX, RGS2, RPL38, RPS4X, RPS6KA2, RPS6KB2, RRAS, RYK, SORT1, S100A11, SERPINB3, SERPINB4, CCL20, CCL21, CCL22, CCL24, CCL25, CX3CL1, SDC4, SDCBP, SELE, SEMG1, SETMAR, SFTPD, SGTA, SHC1, STIL, SKP1, SKP2, SLAMF1, SLC6A4, SLIT3, SLPI, SMPD1, SMPD2, SUMO3, SNTA1, SOD1, SORL1, SOS1, SPINK1, SPINT1, SPN, SPTA1, SPTB, SRP9, STAR, AURKA, STK10, STK11, STYX, XCL2, CNTN2, SERPINA7, CLEC3B, TNFRSF1B, TOP1, TPD52L1, CCT3, TSN, TSC1, UBE2V2, UNG, USP4, KDM6A, UVRAG, VEGFB, VEGFC, VIL1, VIM, VIP, VTN, EIF4H, YWHAG, YWHAZ, RAB7A, AIMP2, NUP214, USP5, AAAS, CDK2AP1, IFT88, AKAP1, SYMPK, SMC1A, BCAR3, LTBP4, RECK, NSMAF, CUL4B, CUL4A, CUL1, FKBP6, SEMA7A, MAPKAPK5, CDC14B, MADD, PRKRA, DDX3Y, PDE5A, EIF3A, EIF3B, EIF3D, EIF3F, EIF3G, EIF3J, PEA15, CDC23, SERPINB7, CRADD, TNFSF14, TNFSF13, TNFSF12, TNFSF10, ADAM9, TNFRSF6B, TNFRSF18, DLK1, TNFRSF10B, TNFRSF10A, IQGAP1, ALDH1A2, CDC123, CDC16, EIF2B4, EIF2B3, EIF2B2, EIF2B5, CDK5R2, HAP1, SOCS3, DIRAS3, USP14, LATS1, SMC3, AIFM1, CCNE2, ZW10, BUB3, DDX21, VAPB, CRLF1, GPR55, S1PR2, SOCS6, TRIP12, TAOK2, SLIT2, SLC9A3R1, LIPG, QKI, PICK1, IL27RA, AKAP6, ATG5, PSMF1, GDF15, TMEM59, BAG5, BAG4, GMFG, APBA3, SEC22B, BRE, CARTPT, TRAF4, NUP155, EIF5B, NUP93, RAPGEF2, PUM1, RIMS2, SLK, RASSF2, DLGAP5, IST1, CTIF, KIAA0141, SFI1, RGP1, PPP1R26, PSMD6, DDX46, NUAK1, OXSR1, TNFSF15, KCNE2, ACOT8, ABI1, PDCD6, BCL2L10, BCL2L11, PARP3, TOM1L1, RANBP9, CTDSP2, RAD50, FEM1B, FRY, TRAP1, AKAP9, EBI3, RASA4, ATP6AP2, FARP1, TNK2, PSME3, EIF1, DDX39A, PRG4, CTDSPL, RAMP2, EIF1B, APC2, ABCA7, ANAPC10, PRG3, CD2BP2, ARIH2, OLFM1, ZER1, EIF3M, CRTAP, STK25, ATG7, ARL6IP5, AGR2, ARFGEF1, CCT7, CCT4, CCT2, GAS2L1, RAD51AP1, IGF2BP3, SPINT2, CCT8, CERS1, NRG3, GIPC1, NUP50, ARPP19, SEC24A, SPINT3, FRS3, USP19, JTB, EDAR, COPS8, OS9, ERP29, TMED10, SPINK5, IL24, ADRM1, UBE2C, NUPL2, CDC37, GLMN, BVES, MAP4K5, RASSF1, FZD10, AKAP13, STK38, EXOSC8 |
2111 | GO:0001818 | 0.01 | 1.77 | 36.65 | 49 | 88 | negative regulation of cytokine production | AXL, BCL3, BPI, BST2, BTK, TSPO, CDH3, CRYBA1, CYLD, GATA3, GATA6, GHSR, IFNG, IL13, IDO1, INHA, LTF, PPM1B, PRG2, RAC1, RARA, RELB, RPS27A, XCL1, SFTPD, SLC11A1, TNFAIP3, TWIST1, UBB, UBA7, SCGB1A1, WNT11, TRIM25, EPX, CD84, TAX1BP1, RPS6KA4, PGLYRP1, IL1RL1, RPS6KA5, KLF4, ATG5, NUTF2, PRG4, TRAIP, KLF2, GPNMB, VSIG4, TUSC2 |
2112 | GO:1903533 | 0.00 | 1.77 | 62.96 | 84 | 151 | regulation of protein targeting | ACTL6A, AGTR2, ANGPT1, BCL3, BMP4, BMP6, BMPR1A, BNIP3L, BRCA1, CD36, CDH1, CDKN1A, CDKN2A, CSNK2A2, CTSK, CYLD, DAB2, ECT2, EDA, EMD, FLNA, GAS6, KAT2A, GNAQ, GPR26, HCLS1, NRG1, HES1, HSP90AB1, IGF1, IL1B, IL10, IL18, ITGAX, JUP, KPNA1, IPO5, SMAD3, TONSL, OGG1, PARK2, PPM1A, PPM1B, PPP3R1, PRKCQ, PSMB7, PSMD8, RAC2, RNASE2, RPL28, SFRP5, SHH, SLC9A1, SNAI2, SREBF1, TRIP6, U2AF1, UBE2L3, ZIC1, ZBTB17, FZD5, AKAP1, BAP1, FZD7, DYRK2, TNFSF14, IL18R1, HDAC3, SLC9A3R1, AKAP6, CABP1, LITAF, BAG4, FAM20B, TRIM28, NUTF2, APC2, ARIH2, TACC3, CREB3, CHERP, RBCK1, EDAR, RBPMS |
2113 | GO:0045216 | 0.03 | 1.77 | 22.41 | 30 | 54 | cell-cell junction organization | ACTN4, APC, SHROOM2, ARL2, CD9, CLDN3, CXADR, ACE, DLG1, ECT2, GJA4, GJA5, GJB1, GJB2, ITGB1, LIM2, PRKACA, PRKCA, PRKCI, RAB13, SNAI2, SNAI1, SRF, STRN, UGT8, WNT11, FZD5, CNTNAP1, CLDN12, CLDN6 |
2114 | GO:1901566 | 0.00 | 1.77 | 79.13 | 106 | 195 | organonitrogen compound biosynthetic process | ACADM, ACHE, AP2A1, ALDH9A1, ALDH3A2, ANGPT1, APOA1, ALDH7A1, CDA, CHKA, CHKB, CKM, CLTC, CSNK1G2, VCAN, CSPG4, DCN, DHODH, DTYMK, DUT, TYMP, ESD, EXT1, EXT2, EXTL1, EXTL2, EXTL3, ACSL3, GPC4, FGF7, GPC5, KDSR, B4GALNT1, B4GALT1, GPC3, GPC1, GSTM1, GSTM2, GSTZ1, HAS1, HAS2, HAS3, HEXA, IL1B, IDO1, LCAT, LUM, CHST6, OAZ1, OAZ2, ODC1, OMD, OGN, P2RX7, PDCL, PCYT1A, PDC, PRKAA1, PRKD1, QDPR, SAT1, SDC1, SDC2, SDC4, SMPD1, SMPD2, SMS, TNFRSF1A, TYMS, UGDH, UGT8, UPP1, BBOX1, NSMAF, PDXK, B4GALT4, B4GALT3, SGPL1, KYNU, VAPB, VAPA, B4GALT6, B4GALT5, GSTO1, CHST3, GAL3ST1, TBPL1, HS2ST1, SDC3, PTDSS1, HS3ST3B1, HS3ST3A1, HS3ST1, ABCC5, GPC6, COL4A3BP, AKR1A1, B3GNT3, CEPT1, ST3GAL6, SPTLC1, CSPG5, CERS1, SLC35D2, KERA, B4GALT7 |
2115 | GO:0051607 | 0.00 | 1.77 | 78.88 | 105 | 189 | defense response to virus | ADAR, ADARB1, AP2A1, AP2B1, AP1G1, ANXA5, BIRC3, ARF1, BCL2, BNIP3, BNIP3L, BST2, C1QBP, CA7, CD4, CD8A, CD28, CD86, CD37, CD40, AP2M1, AP1S1, AP2S1, COX8A, CPA3, CLDN7, CXADR, DEFA1, DMBT1, EIF2S1, STOM, F2RL1, FCGR3B, FGF7, FYN, SLC37A4, HCK, IFI16, IFIT1, IFIT3, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IL2RA, IRF1, IRF5, ISG20, KCNJ8, KCNQ1, MDH1, NTHL1, OAS1, OAS2, OAS3, PDK4, SERPINB10, PPM1B, EIF2AK2, DNAJC3, RAC1, SCN1A, SEC14L1, SNRPD1, SPN, STAT2, TARBP2, TNFAIP3, TRIM25, ZNF189, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, FCN3, OASL, BECN1, AP1S2, AP1M1, HIST1H3F, CHST3, NUP93, PUM1, PHYHIP, IST1, ELMO1, FGFBP1, AP1M2, ABCC9, TRIM22, IFITM3, SPON2, TRIM38, CREB3, ATG7, IFITM2, CSPG5, TRAF3IP2, SERINC3, IFI44L |
2116 | GO:1900180 | 0.04 | 1.76 | 18.69 | 25 | 45 | regulation of protein localization to nucleus | AGTR2, ANGPT1, BCL3, CD36, CDKN1A, CYLD, EMD, GAS6, GNAQ, IL10, TONSL, OGG1, PPM1A, PPM1B, SFRP5, SNAI2, AKAP1, FZD7, DYRK2, SLC9A3R1, CABP1, LITAF, APC2, TACC3, CREB3 |
2117 | GO:0051704 | 0.00 | 1.76 | 224.55 | 299 | 572 | multi-organism process | ABAT, ABCA1, ACOX1, ACP5, ACTA2, ACVR1, ADCY3, ADCYAP1R1, ADH5, NR0B1, ALAD, ANG, ANXA3, APLP2, KLK3, ASS1, ATM, ATP4B, ATRX, BBS2, BBS4, BCL3, BIK, BMP4, BPI, BRCA2, BRDT, BTG1, TSPO, CASP9, CCIN, CCNB1, CD6, CD8A, CD9, CD14, TNFRSF8, TNFSF8, ENTPD2, CD40, CDK6, CLGN, CEBPE, CFTR, CHRNB2, CHUK, CLU, CNP, CNR2, CPS1, CRP, CSF2, CYLC1, CYP1A2, DAZ1, DCN, ACE, DDX1, COCH, DIAPH2, DLD, DNM2, DNMT1, DNMT3A, PHC2, CELSR2, EIF4EBP2, ERCC1, EREG, ETV5, F2R, F3, FANCC, FANCD2, FANCG, FCER1G, FCN2, FGA, FGR, FSHR, B4GALNT1, GAMT, GATA3, GATA4, NR6A1, GDF9, GLRB, GLS, GRID1, CXCL1, CXCL2, CXCL3, HIST1H1T, HIST1H1A, HMGCS2, HOXD11, HP, AGFG1, HRG, HSPB1, IFIT3, IFNA5, IFNA13, IFNA17, IFNA21, IFNGR1, IFNW1, IGF2R, RBPJ, IL1R1, IL10RA, IL12RB2, IL13, TNFRSF9, IL18, ING2, INSL3, IRAK1, IRAK2, IRF1, IRF5, JUND, KCNJ8, KIT, KRAS, LIMK2, LRMP, SMAD1, MEA1, MGST2, CITED1, NRF1, OAS2, ODC1, ODF1, ODF2, TNFRSF11B, OR1D2, CLDN11, OVOL1, PAFAH1B2, PAFAH1B3, SERPINE1, PAWR, SERPINA5, CDK16, PDE4B, PDE4D, PENK, PF4, PF4V1, CFP, PGAM2, PI3, PRG2, PRKACA, PRKACG, PRKCE, MAPK8, DNAJC3, PRM2, PROS1, PTGER1, ARID4A, RGS2, RNASE3, RNF2, RPS6KA2, RPS6KA3, S100A8, S100A9, SBF1, CCL20, CCL22, CXCL6, CXCL5, XCL1, SELE, SELP, SEPP1, SFTPD, SIAH1, SLC11A1, SMARCA2, SNCA, SOX3, SOX9, SPAG1, SPAG4, SPAM1, SPARC, SSTR2, SSTR3, STAR, STK11, STYX, ABCC8, NR2E1, TMF1, TNFRSF1B, TPT1, NR2C2, CCT3, TRPC3, TSPY1, TNFSF4, VIL1, ZAN, ZNF35, ZNF148, DNALI1, FZD5, IFT88, NRIP1, USP9X, USP9Y, EPX, HIST1H2BG, HIST1H2BF, HIST2H2BE, FKBP6, OGT, PPM1D, PARG, PRKRA, TP63, URI1, ADAM9, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, AKAP4, SGPL1, EIF2S2, BCL10, HERC2, HIST1H2BJ, SOCS3, RNF8, RGN, FAM50A, DDX21, DCLK1, BMP15, NRXN3, NRXN1, NRXN2, QKI, PICK1, HAND2, IL27RA, ADAMTS4, ADAMTS2, ADAMTS1, GAL3ST1, LITAF, TBPL1, NR1D1, CLOCK, SPAG6, CEP57, UTP14C, SPATA2, KIAA0196, NR1H4, BCL2L10, ABCC9, IL18BP, AKAP9, FSTL3, SPON2, TUBGCP3, BAIAP2, CRTAP, DEAF1, BATF, CXCL13, CCT7, CCT4, CCT2, CCT6B, CCT8, GJB6, ADAM28, MALT1, PRSS21, SERINC3, IFI44L, CCNI, IL24, PIM2, SOX30, HSF2BP, ADAMTS5, CIT, CD160 |
2118 | GO:0048856 | 0.00 | 1.76 | 64.82 | 89 | 182 | anatomical structure development | ACP2, ADORA1, ADORA2A, ARSE, ASTN1, BCHE, BNIP2, BTD, DAGLA, CBLB, CD40, CDH15, CDK9, CDKN2C, CHRM1, CHRM3, TBCB, CLC, CMKLR1, COX7B, CSRP2, CTH, DLG2, ATN1, RCAN1, DTYMK, DYRK1A, ELAVL3, EXTL1, FGF11, GABRA4, GJB1, GLRB, CXCL1, GSS, IGFBP3, IDO1, MAL, MATN3, MAP3K5, ATXN3, OMP, CLDN11, P2RY1, CNTN3, PENK, SERPINI1, PPP2R5D, PTBP1, PURA, RBM4, SORT1, SCN2B, SCN3A, SLC5A3, SMARCE1, SMPD1, SPG7, TPBG, UFD1L, UNG, RNF103, EPM2A, MAFK, SLC7A5, DPF1, DOC2A, JRKL, RGS9, VNN2, BSN, PAPSS1, AIFM1, EXO1, NRXN2, IL27RA, ADAMTS4, GAL3ST1, RAPGEF5, SPOCK2, SIGMAR1, CHERP, TRIM3, CSPG5, FUT9, RAI1, CPLX2, WWP1, FZD10 |
2119 | GO:1902679 | 0.00 | 1.75 | 268.76 | 352 | 644 | negative regulation of RNA biosynthetic process | ACVR2B, AEBP1, AES, NR0B1, AHR, ANXA4, BIRC5, ARNTL, ASCL2, ATF3, RERE, ATRX, BACH1, CCND1, BCL3, BCL7A, PRDM1, BMI1, BMP4, BMP6, BRCA1, KLF5, C1QBP, CAT, RUNX2, RUNX1T1, CD36, CD38, CDK5, CDKN2A, CDX2, CDX4, CEBPG, CENPF, CHD4, CMKLR1, ATF2, CRY1, CRY2, CRYM, CUX1, CYLD, DAB2, DDX5, DLG1, DNMT1, DNMT3A, DNMT3B, ATN1, TSC22D3, E4F1, EDNRB, EFNA1, EIF4A2, ELF3, ELK3, EN1, EP300, EREG, ESR1, ETS2, ETV3, ETV6, FGF9, FGFR3, FOXD1, FLNA, FRK, GABPA, GAS6, GATA3, GATA6, NR6A1, GFI1, GPS2, ARHGAP35, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, H2AFZ, H3F3B, HCLS1, HDGF, NRG1, HHEX, HIC1, HIF1A, HMGA1, HMX1, FOXA2, HOXD8, PRMT2, HES1, HSBP1, HSPA8, IFI16, IFNA2, IFNG, IGF1R, RBPJ, IL1B, IRAK1, IRAK2, IRF1, IRF2, ISL1, JARID2, JUN, JUNB, JUND, LMO1, SMAD3, SMAD7, MEN1, CIITA, CITED1, TONSL, CNOT2, YBX1, ORC2, OVOL1, PA2G4, PARK2, PAWR, PAX2, PAX9, PBX1, CHMP1A, PEG3, PER1, PEX14, ATP8B1, PHB, PHF2, PIM1, PRRX1, PPID, PPM1A, PROX1, PSMC3, PSMC5, PTCH1, PTGIS, PTHLH, PURA, RARA, RARB, RB1, ARID4A, RBBP8, RBL1, RELB, REST, RFX3, RNF2, RPS27A, RREB1, RXRA, S100A1, SALL1, SATB1, XCL1, SET, SFPQ, SFRP4, SFRP5, SRSF2, SHH, SIAH2, SIX1, SIX3, SNAI2, SMARCA2, SMARCA4, SMARCC2, SMARCE1, SNAI1, SNCA, SOX2, SOX3, SOX5, SOX9, SOX10, SOX11, SP3, SP100, SREBF1, SRF, SRY, STAT3, SUPT4H1, SUV39H1, T, TAF7, TAL1, TBL1X, TBP, NR2F1, NR2F2, KLF10, NR2E1, TNFAIP3, TP73, NR2C1, TRPS1, TSG101, TWIST1, TNFSF4, TNFRSF4, UBB, UBE2D1, SUMO1, UBTF, SCGB1A1, NR1H2, VDR, VEGFA, EZR, WFS1, WHSC1, WNT11, ZFP36, ZIC2, ZNF8, ZNF91, ZNF136, ZNF148, ZNF157, ZNF174, ZNF189, ZNF224, ZP3, LRP8, NRIP1, USP9X, KDM5C, HIST1H4I, CDC45, EOMES, FZD6, FZD8, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NR0B2, CUL3, KLF11, HAT1, CBX4, FCN3, TP63, URI1, EED, CREG1, TRIM24, SAP30, HESX1, HDAC3, NR1I2, PER3, TAX1BP1, HIST1H3F, HIST1H2AG, TAF1C, TAF1B, TAF1A, RNF8, UBA3, BTAF1, USP2, RGN, CBFA2T2, AURKB, RPS6KA5, KLF4, RECQL5, HAND1, HAND2, ZNF254, CIR1, NR1D1, CLOCK, PHF14, KDM4A, ST18, VPRBP, ZNF536, HDAC4, BCLAF1, ZEB2, SETDB1, NR1I3, NR1H4, NR1D2, CASP8AP2, NR2E3, HDAC6, ZNF263, YAF2, TRIM28, SORBS3, OLIG2, TRIB1, COQ7, RAMP3, SAP18, IKZF1, TRIM22, HMG20A, CITED2, IFITM3, MAD2L2, DEAF1, SIVA1, ERN2, HEXIM1, RBCK1, TXNIP, KHDRBS1, CTCF, ZMYND11, ZNF234, ARID5A, CCDC85B, ATF7, VAX1, WWP1, WWP2, STRAP, BAZ2A, KLF12, PHB2, CBX3 |
2120 | GO:0009165 | 0.00 | 1.75 | 43.55 | 58 | 105 | nucleotide biosynthetic process | ADA, ADCY1, ADCY3, ADCY6, ADCY9, ADSL, ADSS, AK2, AK4, AMPD1, AMPD2, APLP1, APRT, AQP1, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, DHFR, DHODH, LPAR1, EDNRB, GALR1, GARS, GNAI3, GRM8, GUCY1B3, GUCY2C, GUCY2F, GUCY2D, HPRT1, HTR2C, IMPDH1, IMPDH2, LDHC, OAS1, OAS2, PRPS2, PRPSAP1, SURF1, UPP1, KYNU, PAPSS2, PAPSS1, AKAP6, ATP5J2, GABBR2, SLC25A13, ATP5H, ATP5L, SLC26A1, ACOT7 |
2121 | GO:0043933 | 0.00 | 1.75 | 49.10 | 66 | 124 | macromolecular complex subunit organization | ABCA1, ADAR, BIN1, APOA4, APOC2, ATR, BICD1, C1QBP, SCARB1, CETP, CIRBP, CLNS1A, DDX1, DDX6, EIF2S3, ACSL3, FECH, GRB7, EIF3E, LCAT, CNOT2, RAD51B, RAD51D, SRSF1, SRSF5, SRSF6, SFSWAP, SNRPC, SNRPD1, SNRPD2, SNRPE, SNRPF, SOX12, SRPK2, TAF2, TARBP2, USP4, NR1H2, XRCC2, SF3A2, SOAT2, PRPF18, EIF3A, EIF3B, EIF3D, EIF3F, EIF3G, EIF3J, SRSF9, DGAT1, CDC123, PRPF3, SCAF11, LIPG, ABCG1, PAN2, ABCA7, CD2BP2, EIF3M, USP39, SRSF10, TXNL4A, SF3A3, PSIP1, STRAP, ATXN2L |
2122 | GO:0045732 | 0.00 | 1.75 | 66.36 | 88 | 159 | positive regulation of protein catabolic process | APC, BARD1, CAV3, CBLB, CCNB1, CDC20, CDC27, CLU, CSNK1D, CSNK2A1, DAB2, GPC3, GPLD1, DNAJB2, IFNG, IL1B, SMAD7, ATXN3, OAZ1, OAZ2, PARK2, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RB1, RDX, RPS27A, SGTA, SKP1, SUMO3, SORL1, SOX9, AURKA, TNFAIP3, TNFRSF1B, UBB, UBE2D1, SUMO1, EZR, VIP, RAB7A, USP5, CUL4B, CUL3, CUL1, CDC23, TNFSF12, ADAM9, CDC16, USP13, RGN, PSMF1, SEC22B, DLGAP5, RNF40, PSMD6, KCNE2, PSME3, TRIB1, APC2, ANAPC10, ARIH2, ATG7, UBE2C, SNF8 |
2123 | GO:0031398 | 0.00 | 1.75 | 50.50 | 67 | 121 | positive regulation of protein ubiquitination | ADRB2, ANGPT1, BIRC3, XIAP, AVPR2, BMI1, BRCA1, CAV3, CCNB1, CDC20, CDC27, CDK9, CLU, FGFR3, DNAJB2, SMAD7, PARK2, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS27A, SKP1, SKP2, SUMO3, UBB, UBE2D1, UBE2L3, UBE3A, WFS1, AIMP2, CUL1, CDC14B, CDC23, RIPK2, CDC16, BCL10, PSMF1, RNF40, PSMD6, PSME3, ANAPC10, MALT1, UBE2C, RASSF1 |
2124 | GO:0045934 | 0.00 | 1.74 | 309.24 | 403 | 741 | negative regulation of nucleobase-containing compound metabolic process | ACVR2B, ACVRL1, AEBP1, AES, NR0B1, AHR, AKT2, ANXA4, BIRC5, APLP1, ARNTL, ASCL2, ATF3, ATM, RERE, ATR, ATRX, BACH1, BARD1, CCND1, BCL3, BCL7A, PRDM1, BMI1, BMP4, BMP6, BMPR2, BRCA1, BRCA2, KLF5, TSPO, C1QBP, CAT, RUNX2, RUNX1T1, CCNT1, CD36, CD38, CDA, CDC6, CDK5, CDK9, CDKN2A, CDX2, CDX4, CEBPG, CENPF, CHD4, CMKLR1, ATF2, CRY1, CRY2, CRYM, CUX1, CYLD, DAB2, DDX5, DFFA, DLG1, DNMT1, DNMT3A, DNMT3B, ATN1, TSC22D3, DUSP1, DYRK1A, E4F1, LPAR1, EDNRA, EDNRB, EFNA1, EIF4A2, ELF3, ELK3, EN1, EP300, ERCC1, EREG, ERCC4, ESR1, ETS2, ETV3, ETV6, FGF9, FGFR3, FOXD1, FLNA, FRK, GABPA, GALR1, GAS6, GATA3, GATA6, NR6A1, GFI1, GNAI3, GPS2, ARHGAP35, GRM8, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, H2AFZ, H3F3B, HCLS1, HDGF, NRG1, HHEX, HIC1, HIF1A, HMGA1, HMX1, FOXA2, HOXD8, PRMT2, HES1, HSBP1, HSPA8, IFI16, IFNA2, IFNG, IGF1R, RBPJ, IL1B, IRAK1, IRAK2, IRF1, IRF2, ISL1, JARID2, JUN, JUNB, JUND, KCNK2, LMO1, SMAD3, SMAD7, MEN1, CIITA, CITED1, TONSL, CNOT2, YBX1, OGG1, ORC2, OVOL1, PA2G4, PARK2, PAWR, PAX2, PAX9, PBX1, CHMP1A, PEG3, PER1, PEX14, ATP8B1, PHB, PHF2, PIM1, PRRX1, PPID, PPM1A, PRKCA, PROX1, PSMC3, PSMC5, PTBP1, PTCH1, PTGIS, PTHLH, PURA, RARA, RARB, RB1, ARID4A, RBBP8, RBL1, RELB, REST, RFX3, RNF2, RPS3, RPS26, RPS27A, RREB1, RXRA, S100A1, S100A11, SALL1, SATB1, XCL1, SET, SFPQ, SFRP4, SFRP5, SRSF2, SRSF4, SRSF6, SRSF7, SFSWAP, SHH, SIAH2, SIX1, SIX3, SNAI2, SMARCA2, SMARCA4, SMARCC2, SMARCE1, SNAI1, SNCA, SOX2, SOX3, SOX5, SOX9, SOX10, SOX11, SP3, SP100, SREBF1, SRF, SRY, STAT3, SUPT4H1, SUV39H1, T, TAF7, TAL1, TBL1X, TBP, NR2F1, NR2F2, KLF10, NR2E1, TNFAIP3, TP73, NR2C1, TRPS1, TSG101, TTF1, TWIST1, TNFSF4, TNFRSF4, UBB, UBE2D1, SUMO1, UBTF, SCGB1A1, NR1H2, VDR, VEGFA, EZR, WFS1, WHSC1, WNT11, ZFP36, ZIC2, ZNF8, ZNF91, ZNF136, ZNF148, ZNF157, ZNF174, ZNF189, ZNF224, ZP3, LRP8, NRIP1, USP9X, KDM5C, SMC1A, HIST1H4I, CDC45, EOMES, FZD6, FZD8, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NR0B2, CUL3, KLF11, HAT1, CBX4, FCN3, TP63, TNKS, SRSF9, URI1, EED, CREG1, TRIM24, SAP30, HESX1, HDAC3, NR1I2, PER3, TAX1BP1, HIST1H3F, HIST1H2AG, TAF1C, TAF1B, TAF1A, RNF8, UBA3, BTAF1, USP2, RGN, SMC3, CBFA2T2, AURKB, RPS6KA5, KLF4, TRIP12, RECQL5, HAND1, HAND2, AKAP6, ZNF254, CIR1, GABBR2, NR1D1, CLOCK, PHF14, KDM4A, DHX34, ST18, VPRBP, ZNF536, HDAC4, BCLAF1, RNF40, ZEB2, SETDB1, NR1I3, NR1H4, NR1D2, PTBP3, CASP8AP2, NR2E3, HDAC6, RAD50, ZNF263, YAF2, TRIM28, SORBS3, OLIG2, TRIB1, COQ7, RAMP3, SAP18, IKZF1, TRIM22, HMG20A, CITED2, IFITM3, MAD2L2, DEAF1, SIVA1, ERN2, HEXIM1, RBCK1, TXNIP, KHDRBS1, CTCF, CERS1, STAG2, ZMYND11, SRSF10, ZNF234, ARID5A, RNPS1, CCDC85B, ATF7, VAX1, WWP1, WWP2, STRAP, BAZ2A, CHEK2, KLF12, PHB2, CBX3 |
2125 | GO:0006811 | 0.00 | 1.74 | 220.77 | 290 | 537 | ion transport | ACTN4, ADA, ADCYAP1R1, ADRB2, ANXA5, ANXA6, SHROOM2, AQP5, AQP7, ARF1, ATF4, ATP12A, ATP1B3, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP4A, ATP4B, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, ATP5O, ATP7B, BAX, BCL2, HCN2, BMP4, CACNA1B, CACNA1E, CACNA1F, CACNA1S, CACNA2D1, CACNG1, CALM3, CAMK2A, CAMK2G, CASQ2, CAV3, CD4, CD63, CDK5, CHRM1, CHRNB4, CLTC, CCR1, CCR5, CNGA1, CNGA2, COX4I1, COX5B, COX6A1, COX6A2, COX6B1, COX7A1, COX7B, COX7C, COX8A, COX15, CP, CTGF, CTSS, CYBA, CYP27B1, DIAPH1, DLG1, DNM2, DPP6, TSC22D3, EDN3, EDNRA, STOM, F2R, FCER1A, FCER1G, FTL, FYN, GAS6, GCG, GIF, GJA4, GJA5, GPM6A, XCR1, FFAR1, GRIA1, GRIA4, GRID1, GRID2, GRIK3, GRIN2A, GSTM2, HPN, HRC, HTR2C, HTR3A, ICAM1, IGF1, IL13, IREB2, ITGAV, ITPR1, ITPR2, ITPR3, KCNA1, KCNA3, KCNA4, KCNA5, KCNA10, KCND2, KCND3, KCNE1, KCNJ2, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ11, KCNJ12, KCNJ13, KCNJ14, KCNJ15, KCNJ16, KCNK2, KCNK3, KCNN1, KCNQ1, KCNS1, KCNS2, KCNS3, LTF, SLC11A2, P2RX3, P2RY1, PAWR, PDE4B, PDE4D, PDPK1, PER1, PIK3C2A, PIK3CG, PLN, PRKACA, PRKCB, PRKCE, PRKD1, RELN, PRSS8, PTPN3, PTPN6, RAF1, RCVRN, REST, RHCE, RHD, RPS27A, RYR1, RYR2, RYR3, S100A1, S100A6, SCN1A, SCN2B, SCN3A, SCN4B, SCN5A, SCN8A, SCN10A, SCNN1A, SCNN1B, SCNN1D, SCNN1G, CCL21, XCL1, SEC14L1, SEMG1, SGK1, SLC5A2, SLC5A3, SLC6A4, SLC8A1, SLC8A3, SLC9A1, SLC9A3, SLC9A5, SLC15A1, SLC15A2, SLC22A1, SLC22A3, SLC22A2, SLN, SNTA1, SPINK1, ABCC8, SURF1, TAF7, TRAPPC10, TPT1, TRPC1, TRPC3, TRPC5, TRPM2, TSC1, TWIST1, UBB, SUMO1, UCN, UCP1, UQCRC1, UQCRFS1, UQCRH, VDR, VIP, WFS1, YWHAH, SLC30A1, SLC30A2, ZP3, TUSC3, CUL5, PICALM, KCNAB2, KCNK5, SNAP23, CD84, ATP6V0E1, HAP1, SLC25A14, RGN, ATP6V0D1, COX7A2L, SLC24A1, KCNAB3, ATP6V1F, COX5A, NRXN1, SLC22A14, KCNK6, GSTO1, AKAP7, AKAP6, ATG5, ATP6V1G1, ATP5J2, HEPH, OXSR1, WDR1, KCNE2, KCNE3, HCN4, ABCC9, COX17, SGK2, AKAP9, CALCRL, KCNMB2, RAMP2, RAMP3, TRDN, CACNG2, RAPGEF3, TOMM40, SLC30A9, ATP5H, SLC9A6, CREB3, CHERP, ATP5L, CLDN16, UQCR11, WWP1, WWP2, CACFD1, IL1RAPL1, CORO1A, SCN11A, TMC6 |
2126 | GO:1903320 | 0.00 | 1.74 | 80.13 | 106 | 192 | regulation of protein modification by small protein conjugation or removal | ADRB2, ANGPT1, APC, BIRC3, XIAP, ARNT, ATM, AVPR2, BMI1, BRCA1, BUB1, BUB1B, TSPO, CAV3, CCNB1, CDC20, CDC27, CDK5, CDK9, CDKN2A, CENPF, CLU, CRY1, DUSP1, FGFR3, FYN, DNAJB2, HSP90AA1, HSP90AB1, LIMK1, MAD2L1, SMAD7, PARK2, PRKCE, PRKCG, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RPS3, RPS27A, SIAH2, SKP1, SKP2, SUMO3, SOX4, TNFAIP3, UBB, UBE2D1, UBE2L3, UBE3A, USP4, WFS1, WNT1, ZNF207, AIMP2, CUL1, OGT, CDC14B, CDC23, RIPK2, CDC16, BCL10, ZW10, BUB3, TRIP12, ATG5, PSMF1, BAG5, HDAC4, RNF40, PSMD6, FEM1B, PSME3, HMG20B, ANAPC10, PIAS3, ZER1, MAD2L2, ATG7, MALT1, UBE2C, GLMN, RASSF1 |
2127 | GO:0030838 | 0.03 | 1.74 | 23.37 | 31 | 56 | positive regulation of actin filament polymerization | ARF1, ARF6, DLG1, CTTN, GRB2, HCK, ICAM1, PFN1, PFN2, PRKCE, RAC1, CCL21, CCL24, VIL1, WASF1, PICK1, BAG4, GMFG, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, ABI2, CDC42EP2, BAIAP2, ARPC1A, CDC42EP3, CDC42EP1, CORO1A |
2128 | GO:1901657 | 0.00 | 1.74 | 52.86 | 70 | 127 | glycosyl compound metabolic process | ALDOB, ALDOC, AMPD2, ARNT, ATP1A2, ATP6V1A, ATP6V1B1, ATP6V1B2, BAD, BPGM, TSPO, AKR1C4, COX4I1, COX8A, COX15, CTNS, DLD, DLG1, DLG2, DLG3, DNMT1, DNMT3A, DNMT3B, DPYD, ENO2, GAMT, GAPDH, GNAI3, GPD1, HIF1A, HK2, HMGCR, HSPA8, IGF1, INS, LDHA, OGDH, P2RX7, ENPP1, PFKFB2, PFKFB4, PGAM2, PGK1, PGK2, PGM1, PPP2R5D, PRKAA1, PTGDR, SDHC, SLC34A1, SNCA, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, SULT2A1, TAZ, UQCRB, UQCRC1, UQCRC2, UQCRH, OGT, AKR1C3, COX5A, ENTPD4, HDAC4, COQ7, AHCYL1, ECD |
2129 | GO:0035966 | 0.00 | 1.73 | 43.82 | 58 | 105 | response to topologically incorrect protein | AARS, ACADVL, ADD1, ASNA1, ASNS, ATF3, ATF4, BAX, CCND1, SERPINH1, CLU, TPP1, CTH, DDX11, EIF2S1, EP300, ERN1, EXTL3, F12, HDGF, DNAJB2, HSPA4, HSPA6, HSPA8, HSPB1, HSP90AA1, HSP90AB1, IFNG, DNAJB9, ATXN3, PARK2, EIF2AK2, DNAJC3, PTPN1, SHC1, SSR1, SULT1A3, UFD1L, WFS1, ZBTB17, MANF, ATP6V0D1, VAPB, EIF2AK3, GOSR2, CUL7, HDAC6, BCL2L11, CTDSP2, PREB, PDIA6, CREB3, AGR2, SEC61B, PDIA5, KDELR3, DNAJB4, SEC63 |
2130 | GO:0007389 | 0.00 | 1.73 | 91.81 | 121 | 220 | pattern specification process | ACVR1, ACVR2A, ACVR2B, ALX3, APC, ATM, BAX, BBS4, BMI1, BMP4, BMPR1A, BMPR2, CDX1, CDX2, CDX4, DNAH5, EDNRA, CELSR2, EGR2, EMX1, EMX2, EN1, EP300, ETS2, EVX1, EYA1, FGF1, FGF3, FGF8, FOXD1, GATA4, KAT2A, GDNF, GPC3, GRSF1, HHEX, HIF1A, FOXA2, HOXC10, HOXC11, HOXD3, HOXD4, HOXD8, HOXD11, HES1, RBPJ, IHH, ISL1, SMAD1, SMAD3, SMAD6, MEOX2, CITED1, NTF4, OTX1, OTX2, PCSK6, PAX1, PAX2, PBX1, PCDH8, PCSK5, PRKACB, MAPK8, RELN, PSKH1, PTCH1, RFNG, RFX3, RFX4, RNF2, SEMA3F, TRA2B, SHH, STIL, SIX1, SIX3, SMARCD3, SNAI1, SOX1, SRF, STC1, AURKA, T, NR2F1, NR2F2, TULP3, KDM6A, VEGFA, WNT1, WNT2, WNT2B, XRCC2, ZIC1, ZIC2, PAX8, FZD5, IFT88, EOMES, OFD1, TP63, CHRD, DNAH11, ALDH1A2, CER1, KIF3B, HAND1, HAND2, SEMA3E, IFT140, ZEB2, ABI1, FRAT1, ATP6AP2, APC2, CITED2, SEMA3A, DMRT2, TBR1, NRG3, SIX2 |
2131 | GO:0007507 | 0.00 | 1.73 | 56.73 | 75 | 137 | heart development | ACVR2B, ADRA1B, ADRBK1, ATM, BBS4, CASP8, COL2A1, COL3A1, COL5A1, ATF2, VCAN, DNAH5, EDNRA, EFNA1, EP300, ERBB2, EYA1, FBN1, GAA, GATA3, GNAQ, HAS2, HHEX, HIF1A, IHH, ILK, ITGA3, ITGA4, JUN, KCNJ8, SMAD3, NTRK3, OXCT1, OXT, PAM, PSKH1, PTCH1, PTN, PTPRJ, RAF1, RPS6KA2, RYR1, SALL1, SCN5A, SHC1, SHH, STIL, SIX1, SMARCD3, SNAI1, SOX4, SOX11, SPARC, TRPS1, TSC2, KDM6A, WHSC1, WNT11, DNAH11, ADAM19, ADAM15, CDKL1, BAZ1B, DHRS3, TRIP11, ADAMTS1, IFT140, RB1CC1, COX17, COL4A3BP, CALCRL, RAMP2, CITED2, OLFM1, HEXIM1 |
2132 | GO:0044700 | 0.00 | 1.72 | 1089.16 | 1332 | 2760 | single organism signaling | A2M, AARS, ABCA1, ABCA4, ABL2, ACADVL, ACTB, ACTG1, ACTN4, ACTL6A, ACVR1, ACVR1B, ACVR2A, ACVRL1, ADA, ADAR, ADCYAP1R1, ADD1, ADRBK1, ADRBK2, AES, AGXT, NR0B1, AHR, AHSG, AKT2, ALK, ALOX15B, AMBP, AMHR2, ANGPT1, ANGPT2, ANXA2, ANXA4, ANXA6, APBB1, APC, BIRC3, XIAP, BIRC5, APLP1, APLP2, APOA1, APOA4, APOC2, KLK3, ARF4, ARL4D, ARF5, ARF6, RND3, ARHGAP4, ARHGAP5, ARHGAP6, ARHGDIB, ARHGDIG, RHOH, ARL1, ARNT, ARR3, ASGR2, ASNA1, ASNS, ATF3, ATF4, ATM, ATOH1, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, ATR, ATRX, AVPR1B, AVPR2, AXL, BAG1, ADGRB2, BAX, BBS2, BBS4, CCND1, BCL2, BCL2A1, BCL2L1, BCL3, BCL9, TNFRSF17, OPN1SW, BDKRB2, BICD1, BID, BIK, PRDM1, BMP1, BMP8B, BMPR1A, BMPR2, BMX, BNIP3, BNIP3L, BOK, DST, BRCA1, BRCA2, BRS3, BSG, BTK, BUB1, BUB1B, C1QBP, C3, CAPN5, C5, DAGLA, CALCR, CAMLG, CAPS, CASP4, CASP8, CASP9, CASP10, CAT, CAV2, CAV3, RUNX2, CBL, CBLB, CCK, KRIT1, CCNC, CCND3, CCNE1, CCNT1, CCNT2, CD2, CD3D, CD3G, CD4, CD5, CD6, CD7, CD8A, CD9, CD14, CD28, TNFRSF8, CD36, SCARB1, CD37, ENTPD2, CD40, CD44, CD53, CD59, CD63, CD69, CD72, CD74, CD79B, CD151, CDA, CDC5L, CDC25C, CDH1, CDH3, CDH6, CDH17, CDK4, CDK6, CDK8, CDK9, CDKN1A, CDKN2A, CDKN2D, CENPA, CENPE, CENPF, CHAD, AKR1C4, CHI3L1, CHKA, CHN1, CHN2, CHUK, CISH, AP3S1, CLCN6, CLU, TPP1, CLPS, CLTA, CCR3, CCR8, ACKR2, CMKLR1, LTB4R, CNGA1, CNTF, COL1A1, COL2A1, COL3A1, COL4A3, COL16A1, CLDN3, CR1, CR2, ATF2, CREBL2, CRY2, CRYAB, CRYBA1, CSF2, CSF2RB, CSH1, CSNK1D, CSNK1G2, CSNK1G3, CSNK2A1, CSNK2A2, CSPG4, CTH, CTLA4, CTNNA1, CTNND1, CTSK, CTSS, CYBA, CYLD, CYP24A1, CYP27B1, DAB2, CD55, DGKA, DGKB, DGKQ, DCC, DCN, DCX, DDB1, GADD45A, DDX3X, DDX5, DDX11, DEFA1, DFNA5, DHCR24, DIAPH1, DIAPH2, DLX5, DMBT1, DNM2, DOK1, RCAN1, HBEGF, DTX1, DUSP1, DUSP4, DUSP5, DUSP7, DUSP9, DYRK1A, E2F2, E2F4, E2F5, GPR183, ECM1, ECT2, EDA, LPAR1, S1PR3, EDN2, EDNRA, EDNRB, CELSR2, EIF2S1, EPHA2, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4EBP1, EIF4G1, EIF4G2, ELF1, ELK1, ELK3, EMD, EMP2, ADGRE1, CTTN, EP300, STOM, EPHA1, EPHA3, EPHA4, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, EPS8, EPS15, ERBB2, ERCC6, ERG, ERN1, ESR1, ESRRG, ETV2, EVC, EXT1, EXT2, EXTL3, EYA1, EYA2, F2R, F2RL1, F3, F7, F10, ACSL1, FBLN1, FBN1, EFEMP1, FCER1A, FCER1G, FCER2, FCGR1B, FCGR2A, FCGR2B, FCGRT, FCN1, GPC4, FGD1, FGF1, FGF8, GPC5, FGFR4, FGR, FOXD1, FLNA, FLT1, FLT3, FLT3LG, FLT4, FPR1, FPR2, FPR3, FRK, CENPI, FSHR, GAST, FUT8, ACKR1, FYB, FYN, IFI6, GABRE, GAP43, GAS1, GAS6, GATA6, GCGR, NR6A1, OPN1MW, GDI1, GDI2, GEM, GFI1, GFRA1, B4GALT1, GH2, GPC3, GMDS, GNA15, GNAQ, GNAT1, GNAT2, GNAZ, GNRH2, GNRHR, GOT1, SFN, GP1BA, GPC1, CCR10, GPR3, GPR4, XCR1, GPR15, GPR17, GPR25, GPR26, GRK6, GPS2, GPX1, GRB7, RAPGEF1, GRID1, GRN, GRINA, ARHGAP35, GRM8, CXCL1, CXCL2, CXCL3, GRPR, GSTM2, GTF2I, GUCA1A, GUCY1B3, GUCY2C, GUCY2F, GUCY2D, H3F3B, HCK, HCLS1, HDGF, NRG1, HHEX, HIC1, HIP1, UBE2K, HIVEP2, HLA-DQA1, NR4A1, HNF4G, ONECUT1, HOXD3, HPGD, HPX, HRG, PRMT2, PRMT1, HSPB1, HSP90AA1, HSP90AB1, ICAM1, ICAM2, IDE, IFI16, SP110, IFIT1, IFIT3, IFNA5, IFNA13, IFNA17, IFNA21, IFNGR1, IFNW1, IGF1, IGF1R, IGF2, IGF2R, IGFBP2, IGFBP3, IGFBP5, IGFBP6, RBPJ, IL1A, IL1R1, IL1RAP, IL2RA, IL2RB, IL2RG, IL10RA, IL11RA, IL12RB2, IL15RA, TNFRSF9, ILK, IMPA1, IMPA2, INCENP, ING2, INPP1, INPP4A, INSIG1, INSRR, IRAK1, ITGA6, IRAK2, IRF1, IRF2, IRF5, ISG20, ITGA1, ITGA3, ITGA4, ITGA5, ITGA7, ITGA9, ITGAD, ITGAE, ITGAL, ITGAM, ITGAV, ITGAX, ITGB1, ITGB4, ITGB5, ITPKB, JUN, JUNB, CD82, KDR, KLK2, KLRB1, KLRC2, KLRC3, KLRD1, KLC1, KPNA1, KPNB1, KPNA4, KPNA5, KRT18, KRT19, LAMA5, LIMK1, LLGL2, LRPAP1, LSP1, LTBP1, LTBP2, LTF, BCAM, CD180, TACSTD2, EPCAM, MAD2L1, SMAD1, SMAD3, SMAD6, SMAD7, MAL, MARK3, CD46, DNAJB9, MAP3K5, MEN1, SCGB2A1, KITLG, CIITA, MAP3K11, FOXO4, CITED1, PPP1R12A, PPP1R12B, SEPT2, CNOT2, NRAS, NRTN, YBX1, NTRK3, DDR2, NTS, NUP88, NUP98, OAS1, OAS2, OAS3, OCRL, OPA1, TNFRSF11B, OR1D2, OR1F1, OR2C1, OR3A1, OR3A2, OTX2, P2RY2, P2RY4, P2RY6, PEBP1, PCSK6, SERPINE1, PAX2, PDCL, PDC, PDE3A, PDE4A, PDE4B, PDE6G, PDE6H, PDE7A, PDE8A, PDE1B, PDGFRL, PDK4, ENPP1, ENPP2, PENK, PER1, PF4, PF4V1, PGAM2, PHB, PIGR, PIK3C2A, PIK3C2B, PIK3C3, PIK3CB, PIM1, PIK3CG, PI4KA, PI4KB, PRRX1, PPM1A, PPM1B, PPP1CA, PPP1R1A, PPP1R2, PPP2CB, PPP2R1A, PPP2R1B, PPP2R5D, PPP4C, PPP3R1, PPP5C, PRCP, SRGN, PRKAA1, PRKAB2, PRKCI, PRKD1, PRKCQ, PRKCSH, PRKG1, MAPK3, MAPK8, EIF2AK2, DNAJC3, KLK6, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTAFR, TAS2R38, PTCH1, PTGDR, PTGER1, PTGIS, PTH1R, PTH2R, PTK7, PTPN1, PTPN6, PTPN13, PTPRA, PTPRD, PTPRE, PTPRJ, PTPRM, PTPRR, RAB4A, RAB6A, RAB13, RAB27A, RAB27B, RABIF, RAB5C, RAC2, RALA, RAN, RANBP2, RAP1GAP, RAP1GDS1, RAP2A, RAP2B, RARB, RASA2, RB1, RBL1, RBM4, RBP1, RBP2, OPN1LW, RCVRN, PRPH2, RDX, RELB, DPF2, RFNG, RFX4, RGR, RGS1, RGS2, RGS10, RGS13, RGS16, RHEB, RLN1, RLBP1, RNF6, RPS3, RPS6, RPS6KB2, RPS19, RPS27, RPS27A, RREB1, RS1, CLIP1, RSU1, RXRA, RXRG, RYK, S100A1, SORT1, S100A4, S100A6, S100A8, S100A11, S100A12, S100A13, SAFB, SAG, SALL1, TSPAN31, ATXN7, SCTR, CCL25, SDC1, SDC2, SDC4, SEC14L1, SEL1L, SELE, SELP, SEMA3F, SFPQ, SFRP4, SFRP5, SGK1, SH3BGR, SH3BGRL, SH3BP2, ITSN1, SHB, SHC1, SIAH1, SIAH2, STIL, SIPA1, SIX3, SKP1, SKP2, SLA, SLAMF1, SLC12A1, SLC20A1, SLIT1, SLIT3, SNAI2, SMARCA4, SMARCC1, SMPD1, SMPD2, SIGLEC1, SNAI1, SOD2, SORL1, SOS1, SOS2, SOX2, SOX9, SOX10, SP1, SP100, SPARC, SPINK1, SPN, SPTA1, SPTB, SRMS, SRPK2, SSR1, STAC, STAT2, STAT3, STAT4, STAT5B, STK10, STK11, STRN, STYX, SULT1A3, XCL2, SYK, T, TACR3, TAF7, TBL1X, DYNLT1, NR2F1, NR2F2, TSPAN7, TNFAIP3, TNFRSF1A, TNFRSF1B, TP73, TPD52L1, TPT1, TPTE, NR2C1, NR2C2, TRAF1, TRAF2, TRHR, TRIO, TRIP6, TRPC3, TRPS1, TSC1, TSC2, TSG101, TUFT1, TULP3, TWIST1, TNFSF4, TNFRSF4, TYK2, TYRO3, TYROBP, UBB, UBA7, UBE2D1, UBE2D2, UBE2V1, UBE3A, SUMO1, UPK1B, SCGB1A1, NR1H2, KDM6A, VAV1, VDAC2, VDR, VEGFA, VEGFB, VEGFC, VIL1, EZR, VIM, TRPV1, VTN, LAT2, CORO2A, WFS1, WNT11, XPA, YWHAZ, ZIC1, ZIC2, ZNF8, TRIM25, ZBTB17, ZP2, ZP3, PXDN, IL1R2, FZD5, SCG2, RAB7A, EPM2A, FZD3, ARHGEF5, NUP214, STAM, SHOC2, CUL5, AAAS, IFT88, ANP32A, RND2, MADCAM1, NRIP1, CLTCL1, USP9X, SMC1A, USP9Y, HIST1H4I, FZD6, FZD7, FZD8, FZD9, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, OR1A1, OR1E1, OR1E2, OR1G1, OR3A3, SPARCL1, SRPX, BCAR3, NSMAF, DYRK2, CUL4A, CUL3, CUL2, CUL1, SORBS2, IRS4, OGT, CDC42BPA, SEMA7A, PIK3R3, ITGA8, IKBKG, IKBKAP, DGKE, COPS3, CAMK1, MAPKAPK5, MADD, PRKRA, OR6A2, RFXANK, UNC5C, SSNA1, OASL, DCHS1, PTCH2, AKR1C3, CHRD, NUMB, PDE5A, DYNLL1, TNKS, BECN1, PEA15, S1PR4, TNK1, TRADD, URI1, CTNNAL1, RIPK1, CRADD, HRK, TNFSF14, TNFSF13, TNFSF12, ADAM15, ADAM9, RIPK2, TNFRSF6B, TNFRSF18, RGS11, RGS9, DLK1, TNFRSF10D, TNFRSF10B, TNFRSF10A, PEX11A, TRIM24, IL18RAP, IL1RL2, IL18R1, INPP4B, NRP2, CFLAR, HDAC3, HCAR3, KAT2B, AKAP4, ALDH1A2, NR1I2, VNN1, SGPL1, TAX1BP1, BUD31, CPNE1, BCL10, WASF1, HIST1H3F, RPS6KA4, ATP6V0E1, PGLYRP1, KALRN, SOCS3, RHBDL1, BAZ1B, TAAR5, UBA3, DOK2, AIP, PSTPIP1, PRC1, ANGPTL1, DIRAS3, RGN, LATS1, ATP6V0D1, RQCD1, SMC3, AIFM1, FIBP, IL1RL1, ARHGEF2, RASSF9, ZW10, BUB3, REPS2, SLC24A1, DCLK1, BMP15, AURKB, XPR1, VAPB, VAPA, CRLF1, DHRS3, RPS6KA5, NUMBL, STK17B, STK17A, CYTH3, CYTH2, ITGB1BP1, BCL7B, TAAR2, GPR55, ATP6V1F, SOCS6, KLF4, NREP, TRIP10, TRIP4, GLP2R, TAOK2, CER1, SLIT2, RAB33A, RAB9A, SLC9A3R1, ZFYVE9, ARHGAP29, ECEL1, GSTO1, ARHGEF6, HAND2, AKAP7, IL27RA, AKAP6, THEMIS2, ONECUT2, PSMF1, ADAMTS3, ADAMTS1, LITAF, BAG5, BAG4, BAG3, RAB3D, ATP6V1G1, BCAR1, GTPBP1, GOSR2, BRE, CDC42BPB, RAB36, TRAF4, AATK, GUCA1C, GNA14, FEZ2, ZNF516, SDC3, TTI1, PHF14, NUP93, PUM1, CEP57, ADAMTSL2, SEMA3E, KNTC1, USP34, GPRASP1, IFT140, ZNF536, SLK, HDAC4, ZFYVE16, RASSF2, RAPGEF5, BCLAF1, SNX17, KIAA0586, CKAP5, SPOCK2, KIAA0141, CUL7, RB1CC1, ARHGEF17, ZEB2, ELMO1, GAB2, C2CD5, FARP2, PSMD6, TRIL, RHOBTB1, NUAK1, DENND4B, P2RY14, ARHGAP25, OXSR1, TNFSF15, NR1I3, NR1D2, RBX1, CASP8AP2, NR2E3, ABI1, SRA1, HDAC6, PDCD6, BCL2L10, BCL2L11, SH2B3, FRAT1, PARP2, TOM1L1, HMGXB4, SH2D3C, SH2D3A, RANBP9, IL18BP, PTPRU, GPC6, COL4A3BP, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN2, TSPAN1, CTDSP2, ARPC2, SGK2, PREB, FEM1B, ARL4C, ARL4A, PDIA6, TRAP1, ARFRP1, G3BP1, EBI3, ABI2, RASA4, ATP6AP2, FARP1, WASF2, SORBS3, TNK2, RNF41, PSME3, CALCRL, TRIB1, RCAN2, RASGRP2, STAM2, RAMP2, RAMP3, AKAP8, FSTL3, EFS, SIGMAR1, TRAIP, APC2, TNIP1, TRIM22, ABCA7, CITED2, SEMA3A, IFITM3, PGRMC2, RBM14, CDC42EP2, IFI30, OLFM1, ACAA2, VAV3, MAD2L2, TRIM38, SLC9A6, CAP2, CAP1, CREB3, STK25, CARM1, SEMA6C, SEMA6B, SEMA4B, BATF, PRDX4, ARL6IP5, AGR2, ARPC1A, AGPAT2, OLFM4, ARFGEF2, ARFGEF1, SIVA1, SORBS1, IFITM2, CDC42EP3, SH2B2, ERLIN1, HEXIM1, RBCK1, STAMBP, IVNS1ABP, TRIM16, TXNIP, PDPN, RASL10A, KHDRBS1, CXCR6, RRAGA, TNFSF13B, EBP, RRH, CNPY3, NRG3, CHL1, TRAF3IP2, NUP50, ZMYND11, OR5I1, CCR9, STARD10, FRS3, PDE10A, CD300C, PROKR1, MALT1, BRD8, EDAR, COPS8, SEC61B, PDIA5, SERINC3, ERP29, RAB40B, FERMT2, RAB32, IL24, KDELR3, IFT27, RAB35, RBPMS, RAB31, ADAP1, PIM2, UPK1A, OGFR, WWP1, ESM1, ADAMTS13, NUPL2, CIT, RCAN3, CD160, ZWINT, CDC42EP1, CDC37, IL1RAPL1, BVES, CORO1A, RABL2B, RABL2A, ERLIN2, STRAP, MAP4K5, RASSF1, CHEK2, FZD10, AKAP13, AKAP11, AKAP10, RASSF8, SEC63, NXPH4, NXPH3, GPR45, USP18, GPR182, STK38, PHB2 |
2133 | GO:0031331 | 0.00 | 1.72 | 67.50 | 89 | 162 | positive regulation of cellular catabolic process | ADRA1B, AKT2, APOA1, APOA4, APOC2, APOH, ARNT, BAX, ZFP36L2, CAV3, CCNB1, CDC20, CDC27, CLU, CSNK1D, DAB2, GPD1, GPLD1, DNAJB2, IGF1, IL1B, INS, SMAD7, P2RX7, PARK2, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPN1, RB1, RDX, RPS27A, SGTA, SKP1, SUMO3, SNCA, AURKA, SUPV3L1, TNFAIP3, TNFRSF1B, TWIST1, UBB, UBE2D1, SUMO1, EZR, ZFP36, USP5, CUL3, CUL1, CDC23, ADAM9, CDC16, RGN, CNOT8, PSMF1, GTPBP1, DLGAP5, RNF40, PSMD6, KCNE2, PSME3, TRIB1, ANAPC10, RAPGEF3, ARIH2, UBE2C |
2134 | GO:0009790 | 0.04 | 1.72 | 19.57 | 26 | 48 | embryo development | DNMT3A, E4F1, ERCC1, ERCC3, FLT3LG, GAMT, NRG1, HOXD8, KDR, KIT, LAMA4, SMAD6, KITLG, PCSK6, PIK3CB, SEMA3F, TOP1, TOP2A, SCEL, TRIP12, PICK1, SH2B3, FRAT1, CITED2, SEMA3A, RAI2 |
2135 | GO:0002831 | 0.00 | 1.72 | 58.43 | 77 | 140 | regulation of response to biotic stimulus | AP2A1, AP2B1, AP1G1, ANXA5, BIRC3, ARF1, PRDM1, BMP6, C1QBP, CA7, CD4, CD28, CD37, AP2M1, AP1S1, AP2S1, COX8A, CPA3, CLDN7, CYBA, CD55, EIF2S1, STOM, F2RL1, FCGR3B, FGF7, FYN, SLC37A4, HCK, HRG, IFIT1, IL2RA, KCNQ1, LTF, CD180, MDH1, NTHL1, PDK4, PGC, SERPINB10, PPM1B, PRKCA, EIF2AK2, KLK7, PVR, RAC1, SCN1A, SEC14L1, SNRPD1, SPN, STAT2, TARBP2, TNFAIP3, ZNF189, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, AP1S2, AP1M1, HIST1H3F, CHST3, NUP93, PUM1, PHYHIP, IST1, ELMO1, FGFBP1, AP1M2, TRIB1, TRIM38, CREB3, CSPG5, TRAF3IP2, SPINK5 |
2136 | GO:0009117 | 0.01 | 1.72 | 37.01 | 49 | 90 | nucleotide metabolic process | ATP1A2, ATP6V1A, ATP6V1B1, ATP6V1B2, BAD, CAT, COX4I1, COX8A, COX15, CTNS, DLD, DLG1, DLG2, DLG3, TYMP, GPX1, HMGCR, HSPA8, IDH1, MDH1, MDH2, NUDT1, NTHL1, OGG1, ENPP1, PGD, PTGIS, RPE, SDHC, SULT1E1, SULT1A1, SULT1A3, SULT1C2, SULT2B1, SULT2A1, TAZ, UNG, UQCRB, UQCRC1, UQCRC2, UQCRH, PDHX, KCNAB2, MBD4, COX5A, TP53I3, ENTPD4, COQ7, NUDT3 |
2137 | GO:0044710 | 0.00 | 1.72 | 258.16 | 340 | 691 | single-organism metabolic process | SERPINA3, ABCA2, ABCA4, ABL2, ABO, ACAT2, ACVR1, ACVR1B, ACVR2A, ACVR2B, ACVRL1, ADAR, PARP4, ALK, AMHR2, AREG, ARF4, ARL1, ART1, ATP6AP1, BACH1, BARD1, BBS4, BCL2, OPN1SW, BMP8B, BMPR1A, BMPR2, CAMK2A, CAMK2G, CAV2, CCNC, CCNH, CDC5L, CDC42, CDKN2D, CD52, CEBPG, CGA, CHI3L1, CHUK, TPP1, CLN5, CCR1, CCR5, COPA, COPB1, CRYAB, CRYBA1, CSF2, CSF2RB, CSNK1D, CTSZ, DAD1, GADD45A, DDX1, DYNC1H1, DYNC1I1, DYNC1I2, HBEGF, DUSP1, DUSP4, DUSP5, DUSP7, DUSP9, GPR183, EDN3, EEF1A2, EFNA1, EPHA2, ELK1, EPHA4, EPHA7, EPHA8, EPHB1, ERBB2, EREG, EYA4, ERCC3, ERCC5, ERCC6, ERN1, ESR1, F2RL1, FANCA, FANCD2, FANCE, FANCG, FGF3, FGF6, FGF8, FGF9, FGFR3, FGR, FLT1, FLT3, FLT4, FPR1, FYN, GALNT1, GAS6, GATA6, OPN1MW, GDF9, GOLGA2, GOLGB1, GPS2, RAPGEF1, GRIN2A, GRM1, HCK, HGF, NRG1, HMGN1, HMGA1, HPX, ICAM1, IGF1R, IL1A, IL1RN, IL2RA, IL2RB, IL2RG, IL18, ILK, INHA, IRAK1, IRAK2, ITGA1, ITGAV, STT3A, JUN, KCNE1, KDR, KISS1, KIT, KRAS, LMAN1, SMAD1, SMAD3, MARK3, MAP3K5, MGAT5, KITLG, MGMT, MAP3K11, TONSL, NRAS, NRTN, NTRK3, TNFRSF11B, PEBP1, PDE6G, PDE6H, PPP2R1A, PPP4C, PPP6C, PRKCG, PRKCSH, PRKCZ, EIF2AK2, DNAJC3, PTPN1, PTPN6, PTPRA, PTPRJ, PTPRR, RAD1, RAB1A, RAC1, RAC2, RAD51B, RAP2A, RASA2, RB1, RBBP8, RBL1, RBL2, RBM3, RBM4, OPN1LW, RGS2, RPN2, RPS6KA1, RPS6KA2, RPS6KA3, RRAS, RYK, S100A12, SERPINB3, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SFTPB, SHC1, SHH, SLAMF1, SLC11A1, SLC12A1, SUMO3, SOS1, SOX9, SPTA1, SPTB, SSRP1, STK10, STYX, SUPV3L1, XCL2, TARBP2, NR2F2, TRAPPC10, TNFRSF1B, TOP2A, TP73, TPD52L1, TRAF2, TSG101, TNFRSF4, TYRO3, UBE2V1, UBE2V2, SUMO1, UVRAG, VEGFB, TRPV1, XPA, XPC, XRCC2, XRCC4, ZNF91, SCG2, SHFM1, ARHGEF5, TUSC3, FZD4, FZD7, FZD8, CUL3, CUL1, IRS4, SEMA7A, PARG, IKBKG, COPS3, CDC14B, MADD, PRKRA, TNFSF11, USO1, DYNLL1, PEA15, GALNT4, EDF1, RIPK1, RIPK2, TNFRSF6B, NR1I2, HERC2, BMP15, ITGB1BP1, COPB2, GPR55, S1PR2, KLF4, TAOK2, SLC9A3R1, COG1, RECQL5, RECQL4, ARHGEF6, GDF15, GOSR1, TMEM59, SEC22B, CHD1L, GOSR2, BRE, CARTPT, TRAF4, KIAA0391, RUBCN, SLK, RASSF2, RB1CC1, OXSR1, NR1D2, PARP2, SH2D3C, SH2D3A, RANBP9, PREB, AKAP9, TRIM28, RASA4, ATP6AP2, CHST4, SORBS3, ALYREF, RNF41, TRIB1, CCNO, TNIP1, ABCA7, SPON1, PPIE, VAV3, SLC30A9, COG5, STK25, RNASEH2A, ARL6IP5, ARFGEF1, RAD51AP1, RGS14, DCTN6, ZMYND11, FRS3, COPS8, KDELR1, ERP29, TMED10, ASCC3, COPS6, PAPD7, TMEM115, ADAMTS13, ADAMTS5, MAP4K5, SUPT16H, FZD10, DCTN3, TREX1, COPE, STK38, PHB2 |
2138 | GO:0098655 | 0.00 | 1.72 | 155.84 | 204 | 375 | cation transmembrane transport | ANXA5, SHROOM2, AQP1, ATP1A2, ATP12A, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP4A, ATP4B, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, ATP5O, ATP7B, HCN2, CACNA1A, CACNA1B, CACNA1E, CACNA1F, CACNA1S, CACNA2D1, CACNB4, CACNG1, SLC25A20, CASQ2, CAV3, CHRNB2, CHRNB4, CCR5, CNGA1, CNGA2, COX4I1, COX5B, COX6A1, COX6A2, COX6B1, COX7A1, COX7B, COX7C, COX8A, COX15, CPT1B, CPT2, CYBA, DIAPH1, DLG1, STOM, GAS6, GPM6A, XCR1, GRIN2A, HPN, HRC, HTR2C, HTR3A, ITGAV, ITPR1, ITPR2, ITPR3, KCNA1, KCNA2, KCNA3, KCNA4, KCNA5, KCNA10, KCND2, KCND3, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ12, KCNJ13, KCNJ14, KCNJ15, KCNJ16, KCNK2, KCNK3, KCNN1, KCNN4, KCNS1, KCNS2, KCNS3, SLC11A2, P2RX3, P2RX4, P2RX7, PDE4B, PDE4D, PIK3C2A, PIK3CG, FXYD3, PLN, PRKAB2, PRKACA, PRKCE, PRKD1, PTPN3, PTPN6, REST, RHAG, RHCE, RHD, RYR1, RYR3, SCN1A, SCN2B, SCN3A, SCN4B, SCN5A, SCN8A, SCN10A, SCNN1A, SCNN1B, SCNN1D, SCNN1G, CCL21, SLC5A5, SLC6A7, SLC7A1, SLC8A1, SLC8A3, SLC9A3, SLC9A5, SLC11A1, SLC12A2, SLC12A3, SLC12A4, SLC13A1, SLC20A1, SLC20A2, SLC22A1, SLC22A3, SLC22A2, SLC22A5, SLN, SNTA1, ABCC8, SURF1, TRAPPC10, TRPC3, TRPC4, TRPC5, TRPM2, UQCRC1, UQCRFS1, UQCRH, TRPV1, YWHAH, SLC30A1, SLC30A2, ZP3, CUL5, KCNAB2, KCNK5, SLC4A4, ATP6V0E1, ATP6V0D1, COX7A2L, SLC24A1, KCNAB3, ATP6V1F, SLC9A3R1, COX5A, KCNK6, ATG5, ATP6V1G1, ATP5J2, OXSR1, HCN4, ABCC9, SLC25A15, KCNMB2, CACNG2, ATP8A1, SLC30A9, ATP5H, SLC9A6, CHERP, SLC34A2, ATP5L, UQCR11, SLC38A3, WWP2, CACFD1, IL1RAPL1, CORO1A, SCN11A |
2139 | GO:1903052 | 0.00 | 1.71 | 46.32 | 61 | 111 | positive regulation of proteolysis involved in cellular protein catabolic process | CAV3, CCNB1, CDC20, CDC27, CLU, CSNK1D, DAB2, DNAJB2, SMAD7, PARK2, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RB1, RPS27A, SGTA, SKP1, SUMO3, AURKA, UBB, UBE2D1, SUMO1, USP5, CUL3, CUL1, CDC23, CDC16, RGN, PSMF1, DLGAP5, RNF40, PSMD6, KCNE2, PSME3, TRIB1, ANAPC10, ARIH2, UBE2C |
2140 | GO:0042451 | 0.03 | 1.71 | 25.04 | 33 | 60 | purine nucleoside biosynthetic process | ADA, ADK, ADSL, ADSS, AK2, AK4, APRT, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, GUK1, HPRT1, IMPDH1, IMPDH2, LDHC, PRPS2, STAT3, SURF1, PAPSS2, PAPSS1, ATP5J2, SLC25A13, ATP5H, ATP5L, SLC26A1, ACOT7 |
2141 | GO:1903828 | 0.02 | 1.71 | 29.63 | 39 | 71 | negative regulation of cellular protein localization | ANGPT1, BARD1, BCL2L1, CAV3, CD36, CDK5, AP2M1, CLTC, CYLD, DAB2, EMD, GAS6, GDI1, GPM6B, IL10, KCNE1, TONSL, PPM1A, PPM1B, SFRP5, SNAI2, SOX4, SP100, TRIP6, AKAP1, DYRK2, OGT, NUMB, TNFSF14, ITGB1BP1, SLC9A3R1, CABP1, LITAF, TMEM59, BAG4, APC2, TACC3, CREB3, OS9 |
2142 | GO:0032956 | 0.00 | 1.71 | 70.11 | 92 | 168 | regulation of actin cytoskeleton organization | ABL2, ADD1, APOA1, SHROOM2, ARF1, ARF6, ARHGAP6, BBS4, BST2, CAPZA1, CAPZB, CAV3, CDK5, CFL2, CTGF, CTSV, DLG1, S1PR1, LPAR1, EFNA5, CTTN, EPHA1, EPHA3, EPHA5, EPS8, F2RL1, GPM6B, GRB2, HCK, HCLS1, HRG, ICAM1, ILK, LIMK1, TACSTD2, SMAD3, NTF3, NTRK3, PAM, PARK2, PFN1, PFN2, PRKCE, PRKCQ, PROX1, PTGER4, RAC1, RDX, S100A10, CCL21, CCL24, SDC4, SLC9A1, SPTA1, SPTB, TAC1, TMOD1, TSC1, VIL1, WNT11, ALMS1, ARHGEF5, WASF1, LATS1, ITGB1BP1, SLIT2, PICK1, BAG4, GMFG, SEMA3E, WDR1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, ABI2, WASF2, SORBS3, RAPGEF3, CDC42EP2, BAIAP2, ARPC1A, ARFGEF1, CDC42EP3, AVIL, CDC42EP1, CORO1A, FZD10, TWF2, SYNPO |
2143 | GO:0048519 | 0.01 | 1.70 | 36.33 | 49 | 99 | negative regulation of biological process | ANXA3, ARL2, CALU, CCK, CCNH, CD28, CNN3, CTNNA2, ENSA, ERCC3, FLOT2, GNAT1, GRID2, GRIN2A, IPO5, PPP1R12A, NUP88, NUP98, OXA1L, PDC, PDE6G, PDE6H, PGGT1B, PGR, PPP1R2, PPP1R8, PTPRN2, ABCE1, SAG, TNFAIP6, TNFRSF1A, TNFRSF1B, TNNI3, TNNT2, TSN, NUP214, AAAS, FKBP6, AIP, APBA3, NUP155, NUP93, PHACTR2, TNK2, NUP50, ARPP19, NUPL2, FICD, FZD10 |
2144 | GO:0090092 | 0.01 | 1.70 | 39.59 | 52 | 95 | regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | ACVRL1, XIAP, BMP1, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, CAV2, CAV3, DAB2, DNM2, FBN1, FOXD1, GATA4, GATA6, GDF9, GPC3, ONECUT1, HES1, RBPJ, ILK, ING2, INHA, ITGA3, LTBP1, SMAD3, SMAD6, CITED1, PCSK6, PDPK1, PPM1A, PPP1CA, RPS27A, SDCBP, SOX11, STK11, UBB, WNT1, LTBP4, ITGA8, CHRD, BMP15, NREP, ZFYVE9, ONECUT2, GDF15, ADAMTSL2, CITED2, GIPC1, RBPMS, STRAP |
2145 | GO:0001764 | 0.02 | 1.70 | 30.44 | 40 | 73 | neuron migration | ASTN1, ATOH1, AXL, BAX, BBS4, CCK, CDK5, DCC, DCX, CELSR2, FYN, GAS6, GATA3, GPM6A, ITGA3, NRCAM, NTRK2, NTRK3, PCM1, PRKG1, RELN, PTPRZ1, SOX1, SRF, CDKL5, CNTN2, NR2F1, NR2F2, TWIST1, FZD3, USP9X, SOX14, PHOX2B, CDK5R2, DCLK1, RAPGEF2, KIAA0319, SEMA3A, CHL1, VAX1 |
2146 | GO:0006821 | 0.03 | 1.70 | 25.87 | 34 | 62 | chloride transport | TSPO, CA2, CA7, CFTR, CLCA1, CLCN2, CLCN3, CLCN5, CLCN6, CLCN7, CLCNKA, CLCNKB, CLNS1A, GABRA4, GABRB2, GABRE, GABRG1, GABRR1, GABRR2, GLRA1, GLRA2, GLRB, P2RY4, P2RY6, SLC26A4, FXYD3, PTAFR, SLC4A1, SLC12A1, SLC12A2, SLC12A3, SLC12A4, BSND, SLC26A1 |
2147 | GO:0051049 | 0.00 | 1.70 | 52.82 | 70 | 133 | regulation of transport | FXYD2, ATP4A, HCN2, CA7, CACNA1B, CACNA1F, CACNA1S, CACNA2D1, CACNB4, CACNG1, CAMK2G, CHRNB4, CLCN2, CLCN3, CLCN5, CLCN6, CLCN7, CLCNKA, CLCNKB, CRY2, GFAP, HTR2C, KCNA1, KCNA3, KCNA4, KCNA10, KCND2, KCND3, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ12, KCNJ13, KCNJ14, KCNJ15, KCNJ16, KCNS1, KCNS2, NTRK2, PDE4B, PER1, PIK3CG, FXYD3, PTPN3, RCVRN, SCN1A, SCN2B, SCN3A, SCN8A, SCN10A, SCNN1B, SLC9A3, SNTA1, TRPC4, VDAC2, PAX8, KCNAB2, KCNK5, RIPK1, KCNAB3, KCNK6, SNCAIP, WDR1, HCN4, CACNG2, CORIN, SCN11A |
2148 | GO:0006475 | 0.02 | 1.70 | 30.46 | 40 | 73 | internal protein amino acid acetylation | ACTL6A, APBB1, ASL, BRCA1, BRCA2, ATF2, EHHADH, EP300, KAT2A, IL1B, ISL1, MDH2, PCK1, PER1, MAPK3, SET, SNAI2, SNCA, TAF5, TAF7, TWIST1, BRPF1, OGT, HAT1, KAT2B, RPS6KA4, RPS6KA5, GTF3C4, ATG5, CLOCK, SUPT7L, ATG7, TRIM16, TAF6L, CTCF, SRCAP, RUVBL2, ARID5A, BRD8, WDR5 |
2149 | GO:0010608 | 0.00 | 1.70 | 117.27 | 153 | 281 | posttranscriptional regulation of gene expression | AARS, ACO1, ADAR, AKT2, ANG, ATF4, BCL3, ZFP36L2, C1QBP, CD28, CDK4, CIRBP, DAZ1, DDX1, DDX3X, DDX6, DHX9, DIO2, EEF2, EIF2S1, EIF2B1, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4EBP1, EIF4EBP2, EIF4G1, EIF4G2, EIF5, EIF5A, ELAVL1, EPRS, ERBB2, FECH, GAPDH, GDNF, GRB7, HSPA8, HSPB1, IGF1, IGFBP5, EIF3E, IREB2, ITGA2, TNPO1, CAPRIN1, SMAD1, SMAD3, CNOT2, YBX1, PA2G4, PER1, EXOSC9, PPP1CA, PRKCA, MAPK3, EIF2AK2, DNAJC3, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTAFR, PURA, RAN, RARA, RBM3, RBM4, RGS2, RPL38, RPS3, RPS4X, RPS6KA1, RPS6KA3, RPS6KB2, RPS27A, RXRA, S100A9, SET, SLC11A1, SOX4, SRP9, TARBP2, TNFRSF1B, TSC1, UBB, UCN, SCGB1A1, VIP, EIF4H, YWHAZ, ZFP36, NUP214, ANP32A, MAPKAPK5, KHSRP, PRKRA, EIF3A, EIF3B, EIF3D, EIF3F, EIF3G, EIF3J, TNFSF13, CDC123, EIF2B4, EIF2B3, EIF2B2, EIF2B5, HAP1, RQCD1, CNOT8, QKI, EIF2AK3, PSMF1, EIF5B, PUM1, CTIF, PSMD6, TRAP1, PSME3, EIF1, EIF1B, PRG3, EIF3M, USP16, IGF2BP3, KHDRBS1, CDC37, EXOSC8 |
2150 | GO:0045595 | 0.00 | 1.70 | 43.07 | 57 | 108 | regulation of cell differentiation | CACNA1A, CD2, CD28, CDC20, CDK9, CHN1, CHRNB2, DBN1, ELAVL1, EMP2, EMX1, CTTN, EPHB3, EYA1, FGF9, FLOT2, GNAQ, GRID2, KRT84, CNOT2, NTF4, PRRX1, PPP2R1A, PRKX, KLK6, PTPN6, RAF1, RAP2A, RPS19, SDC2, ST6GAL1, SLIT1, SLIT3, SNAP25, SOD1, TNFRSF1A, COL14A1, XK, YWHAG, IFT88, SOX14, LTBP4, FOXN1, KLF4, NREP, NR1D1, CLOCK, SOX13, SPOCK2, WDR1, PTBP3, HDAC6, PQBP1, APC2, PDLIM5, TBR1, SPINK5 |
2151 | GO:0080134 | 0.04 | 1.70 | 20.37 | 27 | 51 | regulation of response to stress | ABAT, ALOX12, ANXA2, APOH, HBEGF, F2R, F3, F7, FAP, FGA, FGG, GP1BA, FOXA2, HRG, INSL3, KNG1, REG3A, PRKCQ, PRKG1, RREB1, SELP, SRSF6, TRPC3, USF1, VEGFB, VIL1, ARFGEF1 |
2152 | GO:1903650 | 0.04 | 1.70 | 22.10 | 29 | 53 | negative regulation of cytoplasmic transport | ANGPT1, BARD1, CD36, CDK5, CYLD, EMD, GAS6, IL10, INSIG1, TONSL, PLN, PPM1A, PPM1B, SFRP5, SNAI2, SOX4, SP100, TRIP6, AKAP1, DYRK2, TNFSF14, SLC9A3R1, CABP1, LITAF, BAG4, APC2, TACC3, CREB3, OS9 |
2153 | GO:1901184 | 0.04 | 1.69 | 22.12 | 29 | 53 | regulation of ERBB signaling pathway | ADORA1, ADRA2C, AP2A1, AP2B1, APLP2, CBL, CDC42, AP2M1, AP2S1, CLTA, EPS15, EREG, ESR1, GRB2, RBPJ, ITGA1, PDE6G, PDE6H, PTPRJ, RPS27A, SHC1, SOS1, UBB, RAB7A, STAM, ARHGEF7, HAP1, STAM2, AGR2 |
2154 | GO:0006605 | 0.00 | 1.69 | 56.41 | 74 | 137 | protein targeting | ADAR, ARNTL, RERE, BID, TSPO, CBLB, SCARB2, F2R, FGF9, FYB, GFER, GOLGA1, GOLGA4, HSPA4, HSPA8, HSPA9, HSP90AA1, IFNG, JUN, KPNB1, KPNA4, KPNA5, TNPO1, LTBP2, NUP88, NUP98, OR1D2, PEX1, PEX6, PEX10, PEX12, PEX14, MAPK3, RAB6A, RAB27A, RAN, RANBP2, SIX3, SLC11A1, SORL1, STAT3, SYK, TRPS1, TSC2, YWHAG, YWHAZ, RAB7A, NUP214, AP3B1, AKR1C3, BECN1, AIP, RASSF9, TRIP11, ZFYVE9, PICK1, NUP155, IPO13, NUP93, CEP57, ZFYVE16, TOMM20, AP1M2, KATNB1, TOMM40, TXNIP, SIX2, GIPC1, TOMM34, OS9, CDC37, SNF8, PHB2, GABARAP |
2155 | GO:0006338 | 0.01 | 1.69 | 35.89 | 47 | 86 | chromatin remodeling | ACTB, ACTL6A, RERE, ATRX, BRDT, CDKN2A, CENPA, CHD4, ESR1, CENPI, KAT2A, HMGA1, RB1, RBBP4, SATB1, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCC2, SMARCD3, SMARCE1, SOX9, SUPT4H1, TOP1, TTF1, HIST1H4I, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, TP63, KAT2B, RNF8, BAZ1B, CHD1L, HDAC4, TAF6L, RUVBL2, BAZ2A, CBX3, OIP5 |
2156 | GO:1901659 | 0.02 | 1.69 | 31.30 | 41 | 75 | glycosyl compound biosynthetic process | ADA, ADK, ADSL, ADSS, AK2, AK4, APRT, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, CDA, DHODH, DUT, TYMP, GUK1, HPRT1, IMPDH1, IMPDH2, LDHC, PDCL, PDC, PRPS2, STAT3, SURF1, TYMS, UPP1, PAPSS2, PAPSS1, ATP5J2, SLC25A13, ATP5H, ATP5L, SLC26A1, ACOT7 |
2157 | GO:0018193 | 0.00 | 1.69 | 311.33 | 400 | 746 | peptidyl-amino acid modification | ABL2, ACTL6A, ACVR1, ACVR1B, ADH5, ADORA1, ADRA2C, ADRBK1, AKT2, ALK, ANGPT1, APBB1, BIRC5, APLP2, APOA1, AREG, ARF4, ARNT, ATM, ATR, AVP, AXL, BAX, BCL2, BDKRB2, BGLAP, BLK, BMI1, BMX, BRCA1, BRCA2, BTK, CALM3, CAMK4, CAMK2A, CCK, CCNB1, CD4, CD80, CD36, CD40, CD44, CD59, CD74, CDC42, CDK5, CDKN2A, CGA, CHI3L1, CLK3, CNTF, COPA, COPB1, ATF2, CREBL2, CSF2, CSNK1D, CSNK1G2, CSNK1G3, CSPG4, CTF1, CTH, CTSZ, DAD1, CD55, DCN, ACE, DCX, DHPS, DYNC1H1, DYNC1I1, DYNC1I2, DNMT1, DNMT3B, DPAGT1, DYRK1A, PHC1, PHC2, EEF2, EFNA1, EFNA5, EGR2, EPHA2, EIF5A, EP300, EPHA1, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, ERBB2, EREG, ERCC6, ERN1, EYA1, EZH1, F2R, F7, F10, EFEMP1, FCER1A, FGF7, FGFR3, FGFR4, FGR, FKBP3, FKBP5, FLT1, FLT3, FLT4, FRK, FUT8, FYN, GALNT1, GAPDH, GAS6, GATA3, GCG, BLOC1S1, KAT2A, GFI1, GGCX, B4GALT1, GLB1, GMDS, GOLGA2, GOLGB1, GRIA1, HIST1H1B, HCK, HCLS1, HGF, NRG1, UBE2K, HMBS, HPX, HRC, HRG, PRMT2, PRMT1, HES1, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF1R, IGF2, IL1B, IL12RB2, IL13, IL18, ILK, INCENP, INS, INSRR, ISL1, ITGA5, ITGB1, STT3A, IVL, JARID2, KDR, KIT, LMAN1, SMAD7, MEN1, MGAT2, MGAT5, KITLG, MAP3K11, NTF3, NTRK1, NTRK2, NTRK3, DDR2, NUP88, NUP98, P4HA1, PDE4D, ENPP2, PDPK1, PER1, PFN2, PPIB, PPIC, PPID, PPP2R1A, PPP6C, PRKAA1, PRKACA, PRKCA, PRKCB, PRKCE, PRKCG, PRKCI, PRKD1, PRKCQ, PRKCSH, PRKCZ, MAPK3, MAPK8, EIF2AK2, PRKX, PROC, PROS1, RELN, PTGER4, PTK7, PTPN1, PTPN6, PTPRZ1, RAB1A, RAB3B, RAB6A, RAF1, RANBP2, RAP2B, ARID4A, RNF2, RPN2, RPS6KA2, RYK, S100A8, S100A9, SEL1L, SET, SETMAR, SGK1, SHC1, ST6GAL1, SNAI2, SUMO3, SNCA, SNTA1, SOX4, SP3, SP100, UAP1, SPINK1, SPTA1, SPTB, SRMS, AURKA, STK11, SUV39H1, SYK, TAF5, TAF7, TRAPPC10, TNFRSF1A, TOP1, TOP2A, TWIST1, TYK2, TYRO3, SUMO1, UCN, KDM6A, VEGFA, VEGFB, VEGFC, VRK1, VTN, WEE1, WHSC1, WRN, XPC, XRCC4, PRDM2, LRP8, BRPF1, TUSC3, NUP214, AAAS, SMC1A, BCAR3, DYRK2, TPST2, TPST1, FKBP6, OGT, HAT1, CBX4, CAMK1, MAPKAPK5, STK16, USO1, DYNLL1, TNKS, B4GALT4, B4GALT3, TNK1, EED, RIPK1, RIPK2, TNFRSF18, DYRK4, KAT2B, PROZ, HERC2, P4HA2, RPS6KA4, TNFSF18, BAZ1B, LATS1, SMC3, DYRK1B, ARHGEF2, AURKB, CRLF1, RPS6KA5, COPB2, S1PR2, GTF3C4, B4GALT6, B4GALT5, COG1, EIF2AK3, ATG5, GOSR1, BAG4, RAB3D, SEC22B, GOSR2, CLOCK, AATK, NUP155, TTLL4, KDM4A, NUP93, VPRBP, SETD1A, HDAC4, RASSF2, SPOCK2, SETDB1, SUPT7L, OXSR1, NR1H4, ABI1, HDAC6, GNE, UBA2, SGK2, PREB, AKAP9, ABI2, TRIM28, TNK2, STAG1, CWC27, HMG20B, PIAS3, ST3GAL6, RAPGEF3, SEC24B, PPIE, MAD2L2, PPIH, COG5, SEC23A, CRTAP, CARM1, ATG7, SLC35A1, TRIM16, TAF6L, CTCF, DCTN6, STAG2, NUP50, SEC24A, SRCAP, RUVBL2, ARID5A, BRD8, PRDX3, KDELR1, OS9, TMED10, IL24, TMEM115, WDR5, NUPL2, PRDM7, BAZ2A, CHEK2, DCTN3, COPE, FKBP9, STK38 |
2158 | GO:0060485 | 0.00 | 1.69 | 46.66 | 61 | 112 | mesenchyme development | BCL2, COL1A1, DAB2, EDN3, EDNRA, EDNRB, EFNA1, EPHA3, FGF9, FLNA, GDNF, HAS2, HGF, NRG1, HIF1A, FOXA2, HPN, HES1, LAMA5, SMAD7, KITLG, NRTN, PAX1, PAX2, MAPK3, PTK7, REST, S100A4, SERPINB3, SDCBP, SEMA3F, SHH, SIX1, SNAI1, SOX10, SOX11, TSPY1, WNT2, ZIC2, SEMA3B, EOMES, SEMA7A, ADAM15, ALDH1A2, PHOX2B, HAND1, HAND2, SEMA3E, CUL7, ZEB2, TRIM28, CITED2, SEMA3A, OLFM1, MAD2L2, SEMA6C, SEMA6B, SEMA4F, SEMA4B, SIX2, STRAP |
2159 | GO:0006357 | 0.00 | 1.68 | 51.74 | 68 | 128 | regulation of transcription from RNA polymerase II promoter | ABCA2, ACTL6A, ANXA4, KLF9, CCNE1, CDC6, CHD1, CHD2, CHD3, DGKQ, DHFR, ECM1, ERG, GSC2, HMGN1, HNF4G, MAZ, ORC1, PAM, PFN1, PRKAR1A, PRKCB, PTAFR, PURA, RBL2, RFX2, RRM2, SMARCD3, SMARCE1, SOD2, SP2, SP4, SPIB, STAT2, TAF13, TARBP1, ZNF354A, TYMS, UBE2D2, UCP1, ZIC2, ZNF76, ZNF143, VEZF1, ZNF212, BRD3, CDC45, CUL2, FOXN1, IKBKAP, BLZF1, KLF7, CDK13, CREG1, CTDP1, CIAO1, LITAF, CIR1, ZNF518A, RBX1, SAP18, DEAF1, TAF6L, SRCAP, BRD8, SOX30, SOX21, SNF8 |
2160 | GO:0051222 | 0.00 | 1.68 | 55.15 | 72 | 133 | positive regulation of protein transport | ACTL6A, AKT2, BMP4, BMPR1A, BRCA1, CAMK4, CDC42, CDH1, CDK5, CHRM1, CSNK2A2, CTSK, DAB2, ECT2, EDA, EMD, STOM, ERBB2, ACSL3, FLNA, GAS6, KAT2A, SFN, GPR26, HCLS1, NRG1, HES1, HSP90AB1, IL18, ITGAX, JUP, KPNA1, IPO5, SMAD3, OAZ1, OAZ2, PCM1, PPM1A, PPP3R1, PSMB7, PSMD8, RAC2, RNASE2, RPL28, SHH, SLC9A1, SORL1, TRIP6, TSG101, U2AF1, UBE2L3, ZIC1, ZBTB17, FZD5, ARHGEF5, BAP1, CAMK1, TNFSF14, IL18R1, HDAC3, ITGB1BP1, AKAP6, C2CD5, FAM20B, TRIM28, NUTF2, RAPGEF3, ARIH2, CHERP, RBCK1, EDAR, RBPMS |
2161 | GO:0042176 | 0.01 | 1.68 | 34.44 | 45 | 83 | regulation of protein catabolic process | ANXA2, ARNTL, ATM, BUB1, BUB1B, CDC42, CDKN2A, CENPF, CSNK2A2, DUSP1, FLNA, FYN, GPX1, GRIN2A, NRG1, UBE2K, HSP90AB1, IL10, INS, MAD2L1, SMAD3, ODC1, OPHN1, PHB, PRKACA, PRKCG, PTPN3, SDCBP, SHH, SMARCC1, TMF1, UBE3A, WNT1, ZNF207, USP14, ZW10, BUB3, BAG5, RGP1, MAD2L2, GIPC1, USP19, OS9, GLMN, CHEK2 |
2162 | GO:0000122 | 0.00 | 1.68 | 160.67 | 208 | 385 | negative regulation of transcription from RNA polymerase II promoter | ACVR2B, AEBP1, AES, NR0B1, AHR, ASCL2, ATF3, RERE, ATRX, BACH1, CCND1, PRDM1, BMI1, BMP4, BMP6, KLF5, C1QBP, CD36, CDX2, CDX4, CHD4, ATF2, CRY1, CRY2, CRYM, CUX1, DDX5, DLG1, DNMT1, DNMT3A, DNMT3B, ATN1, TSC22D3, E4F1, EDNRB, EFNA1, EN1, EP300, ETS2, ETV3, ETV6, FGF9, FGFR3, FRK, GABPA, GATA3, GATA6, NR6A1, GFI1, GPS2, ARHGAP35, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HCLS1, HDGF, HHEX, HIC1, HIF1A, HMX1, FOXA2, HOXD8, HES1, HSBP1, IFI16, IFNG, RBPJ, IL1B, IRF2, ISL1, JARID2, JUN, JUNB, JUND, LMO1, SMAD3, SMAD7, MEN1, CIITA, CNOT2, YBX1, ORC2, OVOL1, PARK2, PAWR, PEG3, PER1, PHB, PRRX1, PPID, PPM1A, PROX1, PTCH1, RARA, RARB, RB1, RBBP8, RBL1, RELB, REST, RNF2, RPS27A, RREB1, RXRA, S100A1, SALL1, SATB1, SFPQ, SHH, SIX1, SNAI2, SMARCA2, SMARCA4, SMARCC2, SNAI1, SNCA, SOX2, SOX3, SOX11, SP3, SP100, SREBF1, SRF, SRY, STAT3, SUPT4H1, SUV39H1, T, TAF7, TAL1, TBL1X, NR2F1, NR2F2, KLF10, NR2E1, TP73, NR2C1, TRPS1, TWIST1, UBB, UBE2D1, SCGB1A1, NR1H2, VDR, VEGFA, EZR, WFS1, WHSC1, ZFP36, ZNF8, ZNF136, ZNF148, ZNF157, ZNF174, ZNF189, LRP8, NRIP1, USP9X, EOMES, FZD8, SOX14, UXT, NR0B2, CUL3, KLF11, CBX4, TP63, URI1, EED, SAP30, HDAC3, PER3, RNF8, USP2, AURKB, KLF4, RECQL5, HAND1, ZNF254, NR1D1, PHF14, ST18, VPRBP, ZNF536, HDAC4, ZEB2, SETDB1, NR1H4, NR2E3, TRIM28, SORBS3, OLIG2, COQ7, IKZF1, HMG20A, CITED2, MAD2L2, HEXIM1, TXNIP, CTCF, ZMYND11, ZNF234, ATF7, VAX1, WWP2, STRAP, KLF12 |
2163 | GO:0006469 | 0.00 | 1.68 | 52.17 | 68 | 125 | negative regulation of protein kinase activity | ADAR, ADARB1, APC, BMP4, CAV3, CDKN1A, CDKN2A, CDKN2C, CDKN2D, CHAD, CISH, DCN, GADD45A, DUSP1, DUSP4, DUSP5, DUSP7, DUSP9, EPHA1, GNAQ, SFN, GP1BA, GPS2, HHEX, HMGCR, HSPB1, IGF1R, IL1B, ILK, MEN1, PCP4, PDPK1, PPP1R1A, PPP2R1A, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, DNAJC3, PTPN1, PTPN6, PTPRJ, RB1, RGS2, SERPINB3, SMPD1, SORL1, TAF7, TARBP2, NR2F2, TNFAIP3, TP73, TSC2, YWHAG, CUL3, KAT2B, SOCS3, RGN, LATS1, ITGB1BP1, SOCS6, GMFG, TRIB1, HEXIM1, RGS14, UBE2C, STK38 |
2164 | GO:0010876 | 0.00 | 1.67 | 63.76 | 83 | 153 | lipid localization | ABCA2, ABCA4, AGTR2, AKT2, ALB, ABCD1, ANXA1, APOF, APOA4, APOC2, APOH, BDKRB2, BMP6, TSPO, VPS51, SLC25A20, CETP, CFTR, AKR1C4, CHKA, CLU, CPT1B, CPT2, ACE, FABP6, ACSL1, ACSL3, ACSL4, GALR1, GDF9, GOT2, KCNN4, LCAT, NTSR1, OSBP, OXT, P2RX4, P2RX7, P2RY2, PARK2, SERPINA5, ATP8B1, PRKAB2, PTCH1, ABCD3, RXRA, SCP2, SHH, SLC10A1, SLC10A2, SLCO1A2, SORL1, STAR, SYK, TAC1, TMF1, SLC10A3, FZD4, SOAT2, CYP4F2, TNFSF11, ABCC3, SLC9A3R1, LIPG, OSBPL2, NR1H4, ATP9A, COL4A3BP, ABCC4, SIGMAR1, ABCA7, ABCA10, ABCA9, ABCA8, ATP8A1, SLC25A17, SLCO1B1, STARD10, CFHR4, SLC27A5, SLC27A4, SLC27A2, SLCO2B1 |
2165 | GO:0001933 | 0.01 | 1.67 | 34.49 | 45 | 83 | negative regulation of protein phosphorylation | AMBP, ANGPT1, ATF3, BAX, BDKRB2, CALM3, CCNB1, CRYBA1, DLG1, F2RL1, FBLN1, RAPGEF1, IGF1, IGFBP3, JUN, SMAD3, SMAD6, SMAD7, NTF3, NTRK3, P2RX7, PARK2, PDE4D, ENPP1, PER1, PHB, PPP5C, PRKCZ, PTPRR, SNCA, SPINK1, TWIST1, EZR, OGT, HDAC3, KLF4, SLIT2, SLC9A3R1, RASSF2, RANBP9, CTDSP2, CTDSPL, TNIP1, ZMYND11, STRAP |
2166 | GO:0006066 | 0.01 | 1.67 | 36.02 | 47 | 87 | alcohol metabolic process | ABCA1, ACADL, ACADVL, ADH1B, ADH5, ALDH1A1, ALDH1A3, ALDH3A2, APOF, APLP2, ALDH7A1, BCHE, CALM3, CAT, CETP, CYP8B1, DBI, FDXR, FECH, GALK1, GPLD1, IGF1, INPP4A, INPPL1, ITPKB, LIPA, LIPE, OCRL, RXRA, SLC5A3, SLC34A1, SMPD2, SORL1, TNFSF4, CUBN, NR0B2, SOAT2, DGAT1, INPP4B, ALDH1A2, DHRS3, MINPP1, PPIP5K1, IP6K1, NR1H4, DHRS9, DHRS4 |
2167 | GO:0035108 | 0.02 | 1.67 | 29.19 | 38 | 70 | limb morphogenesis | ALX3, ATRX, BAX, BMP4, BMPR1A, RUNX2, DLX5, DLX6, EN1, FGF8, FGF9, GJA5, GPC3, GNAQ, GNAS, HOXC10, HOXC11, HOXD11, IDUA, IHH, AFF3, PBX1, PCSK5, PRRX1, PTCH1, RARB, SALL1, TULP3, TWIST1, ZNF141, IFT88, FZD6, RECK, TP63, ALDH1A2, HAND2, IFT140, BCL2L11 |
2168 | GO:2000113 | 0.01 | 1.67 | 43.65 | 57 | 107 | negative regulation of cellular macromolecule biosynthetic process | ACVRL1, ADAR, ANG, ATF4, ATR, BMPR2, BRCA2, CDC6, CIRBP, DDX3X, HBEGF, DUSP1, EIF2S1, EIF4E, EIF4EBP1, EIF4EBP2, EPRS, GAPDH, GRB7, IGFBP5, EIF3E, IREB2, KCNK2, CAPRIN1, SMAD1, ENPP1, EIF2AK2, RAN, RBM3, RBM4, RPS3, S100A11, SRP9, TARBP2, TSC1, TTF1, SMC1A, PRKRA, EIF2B4, EIF2B3, EIF2B5, HAP1, RGN, RQCD1, SMC3, CNOT8, QKI, EIF2AK3, TMEM59, PUM1, ACOT8, ABCA7, PRG3, IGF2BP3, CERS1, STAG2, CHEK2 |
2169 | GO:0008645 | 0.01 | 1.66 | 39.23 | 51 | 94 | hexose transport | AKT2, C3, CREBL2, EDNRA, ESR1, G6PC, SLC37A4, GIP, GPC3, FFAR3, NRG1, HK2, IGF1, IL1B, INS, NUP88, NUP98, ENPP1, PRKAA1, PRKCA, PRKCB, PRKCI, PRKCZ, RANBP2, RAP1A, RTN2, SORT1, SLC2A2, SLC2A3, SLC2A4, SLC2A5, SLC5A2, STXBP3, HNF1A, TSC1, TSC2, VIL1, EZR, NUP214, AAAS, CLTCL1, PIK3R3, PEA15, NUP155, NUP93, C2CD5, SORBS1, NUP50, ARPP19, NUPL2, CAPN10 |
2170 | GO:0032649 | 0.04 | 1.66 | 24.62 | 32 | 59 | regulation of interferon-gamma production | ABL2, AXL, BCL3, C1QBP, CD2, CD14, CEBPG, GAS6, GATA3, IL1B, IL10, IL12RB2, IL18, INHA, ISL1, PDE4B, PDE4D, RARA, XCL1, SLC11A1, TNFSF4, SCGB1A1, ZP3, FZD5, TNFSF9, RIPK2, IL18R1, PGLYRP1, IL1RL1, IL27RA, NR1H4, EBI3 |
2171 | GO:0010941 | 0.01 | 1.66 | 40.39 | 53 | 102 | regulation of cell death | ACTN4, ACTN1, ALK, ALX3, BMP1, BMP6, BMP8B, BTK, CASP4, CASP5, CASP10, CD3G, DBH, DCC, EPHB1, ETS1, FLT3, GAS1, GDF9, GRID2, TNFRSF9, ING1, INHA, JUNB, JUND, TNFRSF11B, PHB, SKP2, SOX2, SP100, STK10, TNFRSF1A, TNFRSF1B, TRAF1, TSC1, TNFRSF4, WRN, TRIM24, BMP15, TAOK2, GDF15, BCAR1, TRAF4, SLK, KIAA0141, OXSR1, SRA1, SGK2, FEM1B, SIGMAR1, STK25, ERP29, MAP4K5 |
2172 | GO:0043043 | 0.00 | 1.66 | 144.40 | 186 | 346 | peptide biosynthetic process | AARS, ACO1, AKT2, ANG, SLC25A4, ATF4, BCL3, C1QBP, SLC25A20, CD28, CDK4, CIRBP, SLC25A10, DARS, DAZ1, DDX1, DDX3X, DDX6, DHPS, DIO2, EEF1A2, EEF1B2, EEF2, EIF1AX, EIF2S1, EIF2B1, EIF2S3, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4EBP1, EIF4EBP2, EIF4G1, EIF4G2, EIF5, EIF5A, ELAVL1, EPRS, ERBB2, FAU, FECH, GAPDH, GARS, GGT7, GRB7, GSS, HARS, HSPB1, IGF1, IGFBP5, EIF3E, IREB2, ITGA2, CAPRIN1, MGST2, RPL10A, CNOT2, PA2G4, PCSK1, PCSK5, PER1, PPP1CA, MAPK3, EIF2AK2, DNAJC3, PTAFR, PURA, QARS, RARA, RBM3, RBM4, RGS2, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL36AL, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS6KA1, RPS6KA3, RPS6KB2, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, RXRA, S100A9, SLC25A1, SOX4, SOX11, SRP9, SRP14, SRP19, SRP68, SSR1, SSR3, TARBP2, TARS, TSC1, TUFM, UCN, UCP1, EIF4H, ZFP36, AIMP2, SLC25A16, MAPKAPK5, DENR, DDX3Y, EIF3A, EIF3B, EIF3D, EIF3F, EIF3G, EIF3J, CDC123, EIF2B4, EIF2B3, EIF2B2, EIF2B5, EIF2S2, HAP1, SLC25A14, RPL14, EIF1AY, RQCD1, CNOT8, RPL23, QKI, EIF2AK3, GTPBP1, EIF5B, PUM1, SPCS2, CTIF, TSFM, TRAP1, SLC25A13, SLC25A15, EIF1, EIF1B, TNIP1, PRG3, SLC25A17, EIF3M, USP16, IGF2BP3, KHDRBS1, FARS2, SEC61B, RPL35 |
2173 | GO:0032101 | 0.00 | 1.65 | 53.12 | 69 | 130 | regulation of response to external stimulus | ACTL6A, AP2A1, AP2B1, AP1G1, ARF1, CA7, CD4, CD36, CD37, AP2M1, AP1S1, AP2S1, COX8A, CPA3, CLDN7, CSNK2A2, CTSK, EIF2S1, CTTN, STOM, ERN1, F2R, FCGR3B, FGF7, FYN, SLC37A4, KAT2A, FOXA2, KCNQ1, MDH1, NTHL1, PARK2, PDK4, SERPINB10, PRKCG, RPL28, SCN1A, SELP, SNRPD1, SREBF1, STAT2, SYK, U2AF1, ZBTB17, ZNF189, FZD5, RAB7A, IFT88, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, TRIM24, AP1S2, AP1M1, HIST1H3F, RAB33A, CHST3, NUP93, PHYHIP, IST1, ELMO1, FGFBP1, HDAC6, AP1M2, CSPG5, TRAF3IP2 |
2174 | GO:0030030 | 0.00 | 1.65 | 242.78 | 311 | 591 | cell projection organization | ACTB, ACTG1, ADAM10, ADCY1, AP2A1, AP2B1, ANGPT1, APOA1, APOA4, AREG, ARF4, RERE, ATOH1, ATP2B2, BBS1, BBS2, BCL2, TSPO, CACNA1F, CACNA1S, CACNB4, CALM3, CALU, CAMK2A, CAMK2G, CCK, CD72, CDH1, AP2M1, AP2S1, CLU, CLTA, CNP, COL2A1, COL3A1, COL4A3, COL4A4, COL4A5, COL5A1, COL5A2, COL6A2, COL6A3, COL9A1, COL9A3, CSF2, CSF2RB, CSNK1D, CSNK2A1, CSNK2A2, CTNNA1, CTNNA2, DCX, DHFR, DLG1, DLG3, DLX5, DNM1, DNAH5, HBEGF, ECM2, DUSP5, DUSP7, DUSP9, E2F4, E2F5, S1PR1, EFNA3, EFNA4, EFNB2, CELSR2, EGR2, EMP1, EMP2, EMP3, EMX1, EPHA1, EPHA5, EPHA8, ERBB2, EREG, ETV1, ETV4, EXT1, ACSL4, FGD1, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FLNA, BLOC1S1, GDNF, GFRA1, GPC1, GRB2, GRIN2A, ONECUT1, HPRT1, PRMT1, HSPA8, HSP90AA1, HSP90AB1, TNC, IL2RA, IL2RB, IL2RG, INPPL1, ITGA6, ISL1, ITGA1, ITGA5, ITGA9, ITGAV, ITGB4, JUN, KIF5A, KRAS, LAMA5, ABLIM1, MAP6, MARK3, RAB8A, KITLG, NUBP1, SEPT2, SLC11A2, NRAS, NRTN, NTF3, NTF4, NTN3, OCRL, OGN, OPHN1, OTX2, PEBP1, PAX2, PCM1, CDK16, PPP5C, PRKCZ, PRKG1, MAPK3, PSPN, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTPRA, PTPRM, RAB3A, RAB13, RAC3, RAF1, RASA2, RB1, RFX3, RFX4, RPGR, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RRAS, RXRA, RYK, S100A6, S100B, SCN5A, SDC4, SDCBP, ITSN1, SHC1, SHH, SIAH1, SIAH2, STIL, SOD1, SOS1, SOS2, SPAG1, SPAST, SPTA1, SPTB, AURKA, STRN, STXBP1, TBCE, DYNLT1, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TSC1, TULP1, TYROBP, UBB, UCN, UGT8, VCL, WEE1, ZIC2, FZD3, FGF23, USP9X, PICALM, CUL4B, CUL3, OFD1, CNTNAP1, ITGA8, CDC14A, KLF7, UNC5C, SSNA1, NUMB, DYNLL1, PEA15, IQGAP1, NRP2, AKAP4, CPNE1, PHOX2B, WASF1, RPS6KA4, KALRN, ATP6V0D1, DCLK1, VAPA, RPS6KA5, S1PR2, NREP, SNAP29, SLC9A3R1, NRXN3, ARHGEF6, CHST3, ONECUT2, PSMF1, BAG4, SPAG6, FEZ2, IQCB1, CROCC, CCP110, KIAA0586, FARP2, PSMD6, RBX1, ABI1, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN2, NUBP2, FRY, AKAP9, RASA4, FARP1, PSME3, ABCC4, CCNO, SPON2, SEC24B, VAV3, SLC9A6, CAP2, CAP1, ATG7, ARPC1A, ARFGEF1, DPYSL4, CHL1, FRS3, EHD1, IFT27, RAB35, VAX1, KIF3A, CORO1A |
2175 | GO:0006606 | 0.05 | 1.64 | 22.37 | 29 | 54 | protein import into nucleus | ADAR, AGTR2, RERE, CBLB, F2R, FGF9, FYB, GNAQ, HES1, JUN, KPNA4, KPNA5, NUP88, NUP98, MAPK3, RANBP2, STAT3, SYK, TRPS1, TSC2, NUP214, FZD7, RPL23, ZFYVE9, NUP155, IPO13, NUP93, TXNIP, SIX2 |
2176 | GO:0044708 | 0.02 | 1.64 | 30.08 | 39 | 73 | single-organism behavior | ABAT, AGTR2, BBS2, BBS4, BRS3, TSPO, CACNA1A, CACNB4, CHRNB4, CLCN3, CNP, DNM1, EPHA4, EPS8, ETV1, GDNF, GFI1, GHSR, GLRA1, GLRB, FOXA2, KCND2, KCNJ10, P2RX3, PRKCE, SCN1A, SCN8A, SNCA, TBCE, TMOD1, TRH, TSC1, TRPV1, ZIC1, USP2, CARTPT, PUM1, ATG7, CHL1 |
2177 | GO:0007163 | 0.01 | 1.64 | 37.14 | 48 | 89 | establishment or maintenance of cell polarity | APC, AQP1, ARF4, ARF6, DST, KRIT1, CD3G, CDC42, CDX2, CENPA, CTNNA1, DLG1, DLG3, EPHB1, EYA1, FLOT2, GATA3, IGF1, ILK, LLGL2, NUMA1, PRKCI, PRKCZ, PTK7, CCL21, SFRP5, SHH, SLC9A1, SPN, STK11, DYNLT1, WEE1, WNT11, LIN7A, MAP7, ARHGEF2, ZW10, CYTH3, SLC9A3R1, CDC42BPB, CKAP5, ACTR2, RNF41, CAP2, CAP1, STK25, ARFGEF1, SPINT2 |
2178 | GO:0035113 | 0.03 | 1.64 | 26.29 | 34 | 63 | embryonic appendage morphogenesis | ALX3, BAX, BMP4, BMPR1A, RUNX2, DLX5, DLX6, EN1, FGF8, FGF9, GJA5, GPC3, GNAQ, GNAS, HOXC10, HOXC11, HOXD11, IHH, AFF3, PBX1, PRRX1, PTCH1, RARB, SALL1, SHH, TULP3, TWIST1, IFT88, FZD6, RECK, TP63, ALDH1A2, HAND2, BCL2L11 |
2179 | GO:1902580 | 0.00 | 1.64 | 180.83 | 232 | 441 | single-organism cellular localization | ACTL6A, ADORA1, AKT2, ALB, ANXA2, ARF6, ASNA1, ATM, ATP1B3, ATP2A1, BAD, BAX, BBS1, BBS2, BBS4, BCL2, BCL2L1, BID, BNIP3L, BRCA2, BSG, TSPO, CALCR, CASP8, CAV3, CCNB1, CD2, SCARB2, CDH3, CDKN2A, CENPA, CENPE, AP2M1, CLTC, COPA, COPB1, CSNK2A2, CTSK, DLG1, DLG2, DLG3, DYNC1H1, DPP6, EPHA2, EMP2, STOM, ERBB2, ETV5, EYA1, ACSL3, FAU, FLOT2, FNTA, KAT2A, GDI1, GFER, GLRB, GOLGA1, GOLGA4, SFN, GPR26, NRG1, HSPA4, HSPA8, HSPA9, HSP90AA1, ITGA3, ITGA4, ITGAL, ITGAX, ITGB1, KCNE1, KRT18, LAMA5, LLGL2, MAL, RAB8A, RPL10A, NUMA1, OXA1L, P2RY1, CHMP1A, PEX1, PEX6, PEX10, PEX12, PIGR, PRKCI, MAPK8, RELN, PSMB7, PSMD8, PTCH1, PTN, PEX19, PEX5, RAB13, RAB27B, RAC1, RAP2A, RB1, RDX, RNASE2, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, CLIP1, S100A10, SCP2, SDCBP, SLC12A1, SORL1, SREBF1, SRP9, SRP14, SRP19, SRP68, SSR1, SSR3, DYNLT1, TNFRSF1A, TULP1, TULP2, TULP3, U2AF1, UBE2L3, SUMO1, UVRAG, VIL1, EZR, WRB, YWHAG, YWHAH, YWHAZ, ZBTB17, FZD5, RAB7A, MADCAM1, UBL4A, BAP1, OGT, BLZF1, SSNA1, NUMB, DYNLL1, BECN1, CDC23, RAB11A, RPL14, AIP, MAP7, ARHGEF2, ZW10, RAB11B, ITGB1BP1, COPB2, TRIP11, TAOK2, NRXN1, NRXN2, PEX16, CRIPT, PICK1, TMEM59, BAG4, RAPGEF2, ZFYVE16, DLGAP5, SPCS2, TOMM20, C2CD5, FAM20B, BCL2L11, ACTR2, ARFRP1, RAMP2, RAMP3, KATNB1, ATP8A1, ARIH2, TOMM40, AGR2, SORBS1, VAMP5, TOMM34, FERMT2, RAB31, RER1, RPL35, SEC63, SNF8, COPE |
2180 | GO:0061024 | 0.00 | 1.64 | 51.00 | 66 | 125 | membrane organization | ACTB, ACTG1, AP2B1, AP1G1, ARF4, CALM3, CD36, AP1S1, AP2S1, CLCN3, CLTA, CD55, DHCR24, DYNC1H1, DYNC1I1, DYNC1I2, EPS15, F2RL1, FTL, BLOC1S1, GJB1, GJB2, GOLGB1, HIP1, HSPA8, INS, ITGA2, MFGE8, CHMP1A, PIK3C2A, PRKAB2, RAB4A, RABIF, RALA, SGCD, SLC2A4, STXBP3, UBB, UPK2, STAM, PICALM, BECN1, AP1S2, AP1M1, RABEP1, AP4M1, KIF3B, COG1, CLINT1, PUM1, DNAJC6, ELMO1, SNAP91, PDCD6IP, AP1M2, STAM2, COG5, EXOC5, DCTN6, AP4B1, KDELR1, TMEM115, KIF3A, AP4S1, DCTN3, SNF8 |
2181 | GO:0010827 | 0.03 | 1.63 | 27.13 | 35 | 65 | regulation of glucose transport | AKT2, C3, CREBL2, ESR1, GIP, GPC3, FFAR3, HK2, IGF1, IL1B, INS, NUP88, NUP98, ENPP1, PRKAA1, PRKCA, PRKCB, PRKCI, PRKCZ, RANBP2, RAP1A, RTN2, NUP214, AAAS, CLTCL1, PIK3R3, PEA15, NUP155, NUP93, C2CD5, SORBS1, NUP50, ARPP19, NUPL2, CAPN10 |
2182 | GO:0008064 | 0.01 | 1.63 | 38.81 | 50 | 93 | regulation of actin polymerization or depolymerization | ADD1, SHROOM2, ARF1, ARF6, BBS4, CAPZA1, CAPZB, CFL2, DLG1, CTTN, EPS8, F2RL1, GRB2, HCK, HCLS1, ICAM1, PFN1, PFN2, PRKCE, RAC1, RDX, CCL21, CCL24, SPTA1, SPTB, TMOD1, VIL1, WASF1, LATS1, SLIT2, PICK1, BAG4, GMFG, WDR1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, ABI2, CDC42EP2, BAIAP2, ARPC1A, ARFGEF1, CDC42EP3, AVIL, CDC42EP1, CORO1A, TWF2 |
2183 | GO:0044106 | 0.03 | 1.63 | 29.46 | 38 | 71 | cellular amine metabolic process | ACHE, APOA1, APOA4, ARG1, ARG2, ASL, ASS1, ALDH7A1, BCHE, CCBL1, CETP, CHKA, CHKB, CKM, CPS1, DBI, DDC, DHPS, FGF7, GAMT, GOT1, GPLD1, IDO1, LCAT, OTC, PCYT1A, ENPP2, SAT1, SLC6A8, SMPD1, SMPD2, SMS, TRH, KYNU, SLC25A15, CEPT1, PRG3, SMPDL3A |
2184 | GO:0090287 | 0.05 | 1.63 | 23.25 | 30 | 56 | regulation of cellular response to growth factor stimulus | ACVR2A, ACVRL1, AGTR2, XIAP, BMP4, BMPR2, RUNX2, CD63, DCN, FGF1, FOXD1, GATA3, GATA4, GATA6, GPC3, GPC1, HRG, HES1, RBPJ, ILK, OTX2, PCSK6, CHRD, CER1, SLIT2, ADAMTS3, FGFBP1, FSTL3, SLC9A6, CXCL13 |
2185 | GO:0044801 | 0.02 | 1.62 | 34.22 | 44 | 82 | single-organism membrane fusion | ADRB2, AKT2, ANXA1, ANXA2, BAX, BCL2A1, BNIP3, CAV2, CD9, GNAI3, LRMP, RAB8A, OPA1, PARK2, SERPINA5, RAB3A, SLAMF1, SNAP25, SPAM1, STXBP1, SYT1, SYT4, TSG101, UVRAG, RAB7A, DYSF, EEA1, TPST2, USO1, VAMP8, STX16, STX11, STX10, SNAP23, SEC22C, SNAP29, GOSR1, SEC22B, RUBCN, C2CD5, STX6, VAV3, VAMP5, CORO1A |
2186 | GO:0042455 | 0.03 | 1.62 | 28.80 | 37 | 69 | ribonucleoside biosynthetic process | ADA, ADK, ADSL, ADSS, AK2, AK4, APRT, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, DHODH, GUK1, HPRT1, IMPDH1, IMPDH2, LDHC, PDCL, PDC, PRPS2, STAT3, SURF1, UPP1, PAPSS2, PAPSS1, ATP5J2, SLC25A13, ATP5H, ATP5L, SLC26A1, ACOT7 |
2187 | GO:0006903 | 0.05 | 1.62 | 23.37 | 30 | 56 | vesicle targeting | AREG, ARF1, CD59, COPA, COPB1, CSNK1D, CTSZ, GOLGA2, GRIA1, LMAN1, LRMP, SEPT5, PPP6C, RAB1A, TRAPPC10, CUL3, USO1, SNAP23, COPB2, SNAP29, GOSR1, SEC22B, GOSR2, AP1M2, PREB, SEC24B, SEC23A, SEC24A, TMED10, COPE |
2188 | GO:0010563 | 0.00 | 1.61 | 116.02 | 148 | 278 | negative regulation of phosphorus metabolic process | ADAR, ADARB1, AHSG, AMBP, ANGPT1, APC, APLP1, RHOH, ATF3, BAX, BDKRB2, BMP4, TSPO, CALM3, CAV3, CCNB1, CDA, CDKN1A, CDKN2A, CDKN2C, CDKN2D, CHAD, CISH, CRY2, CRYBA1, DCN, GADD45A, DLG1, DLG2, DLG3, DUSP1, DUSP4, DUSP5, DUSP7, DUSP9, LPAR1, EDNRA, EDNRB, EPHA1, F2RL1, FBLN1, GALR1, GNAI3, GNAQ, SFN, GP1BA, GPS2, RAPGEF1, GRM8, HHEX, HMGCR, FOXA2, HPN, HSPB1, IGF1, IGF1R, IGFBP3, IL1B, ILK, INHA, JUN, SMAD3, SMAD6, SMAD7, MEN1, NTF3, NTRK3, P2RX7, PARK2, PCP4, PDE4D, ENPP1, PDPK1, PER1, PHB, PPP1R1A, PPP2R1A, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCZ, DNAJC3, PRPSAP1, PTPN1, PTPN6, PTPRJ, PTPRR, RANBP2, RB1, RGS2, ATXN7, SERPINB3, SMPD1, SNCA, SORL1, SPINK1, STAT3, TAF7, TARBP2, NR2F2, TNFAIP3, TP73, TSC2, TWIST1, EZR, YWHAG, AKAP1, CUL3, OGT, DYNLL1, URI1, IQGAP1, HDAC3, KAT2B, SOCS3, RGN, LATS1, ITGB1BP1, SOCS6, KLF4, SLIT2, SLC9A3R1, AKAP6, BAG4, GMFG, GABBR2, RUBCN, HDAC4, RASSF2, SFI1, PPP1R26, RANBP9, CTDSP2, FARP1, CTDSPL, TRIB1, TNIP1, CD2BP2, HEXIM1, RGS14, ZMYND11, PRDX3, UBE2C, STRAP, STK38 |
2189 | GO:0000723 | 0.05 | 1.61 | 24.18 | 31 | 58 | telomere maintenance | ATM, ATR, ATRX, ERCC1, ERCC4, PRKCQ, MAPK3, RAD51D, SP100, CCT3, WRN, HIST1H4I, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, MAPKAPK5, TNKS, AURKB, DCLRE1A, PARP3, RAD50, CCT7, CCT4, CCT2, CCT8 |
2190 | GO:1903651 | 0.01 | 1.61 | 50.78 | 65 | 122 | positive regulation of cytoplasmic transport | ACTL6A, ARF1, BMP6, BMPR1A, BRCA1, CAMK4, CDH1, CSNK2A2, CTSK, DAB2, ECT2, EDA, EMD, ACSL3, FLNA, GAS6, KAT2A, SFN, GPR26, HCLS1, NRG1, HES1, HSP90AB1, IGF1, IL1B, IL18, ITGAX, JUP, KPNA1, IPO5, SMAD3, PPM1A, PPP3R1, PRKCQ, PSMB7, PSMD8, RAC2, RDX, RNASE2, RPL28, SHH, SLC9A1, SORL1, TRIP6, U2AF1, UBE2L3, EZR, ZIC1, ZBTB17, FZD5, BAP1, CAMK1, TNFSF14, IL18R1, HDAC3, FAM20B, TRIM28, NUTF2, RAPGEF3, ARIH2, CHERP, RBCK1, KHDRBS1, EDAR, RBPMS |
2191 | GO:0030001 | 0.00 | 1.61 | 114.35 | 146 | 277 | metal ion transport | ANXA5, ANXA6, SHROOM2, AQP1, ATP12A, ATP2A1, ATP2B1, ATP4A, ATP4B, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, ATP7B, HCN2, CACNA1A, CACNA1E, CACNA1F, CACNA1S, CACNG1, CDK5, CHRNB2, CLCA1, CLTC, CCR5, CNGA1, CNGA2, CP, CTGF, CYP27B1, FTL, FYN, GAS6, GIF, GJA4, GJA5, GPM6A, XCR1, GRIN2A, HPN, HTR2C, HTR3A, IREB2, ITGAV, ITPR1, ITPR2, ITPR3, KCNA1, KCNA2, KCNA3, KCNA4, KCNA10, KCND2, KCND3, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ12, KCNJ13, KCNJ14, KCNJ15, KCNJ16, KCNK2, KCNK3, KCNN1, KCNN4, KCNS3, SLC11A2, PRKCB, REST, RYR1, RYR3, SCN1A, SCN3A, SCN8A, SCN10A, SCNN1A, SCNN1D, SCNN1G, CCL21, SLC5A2, SLC5A3, SLC5A5, SLC6A8, SLC8A3, SLC9A5, SLC10A1, SLC10A2, SLC11A1, SLC12A1, SLC12A2, SLC12A3, SLC12A4, SLC13A1, SLC34A1, SLC20A1, SLC20A2, SLC22A5, TRAPPC10, TPT1, TRPC5, TRPM2, TSC1, VDR, TRPV1, SLC30A2, TUSC3, CUL5, PICALM, KCNK5, SLC4A4, SLC5A6, ATP6V0E1, SLC13A2, ATP6V0D1, SLC24A1, KCNAB3, RAB11B, ATP6V1F, KCNK6, SLC4A8, ATP6V1G1, HEPH, SLC23A2, HCN4, ABCC9, COX17, CALCRL, KCNMB2, RAMP2, RAMP3, CACNG2, SLC30A9, SLC9A6, CHERP, SLC34A2, SLC38A3, CACFD1, IL1RAPL1, SCN11A |
2192 | GO:0043624 | 0.04 | 1.61 | 25.73 | 33 | 62 | cellular protein complex disassembly | ADD1, APC, SHROOM2, CAPZA1, CAPZB, CCNB1, CFL2, EPS8, F2RL1, NRG1, HSPA8, PEX14, RDX, SGK1, SLN, SPAST, SPTA1, SPTB, AURKA, TMOD1, VIL1, SYNJ1, ARHGEF2, AURKB, DNAJC6, WDR1, HDAC6, APC2, KATNB1, GAS2L1, AVIL, STMN2, TWF2 |
2193 | GO:0006733 | 0.03 | 1.61 | 30.46 | 39 | 73 | oxidoreduction coenzyme metabolic process | ALDOB, ALDOC, ARNT, BPGM, DLD, ENO2, GAPDH, GPD1, HIF1A, HK2, HMGCR, IDH1, IGF1, INS, LDHA, MDH1, MDH2, OGDH, P2RX7, PFKFB2, PFKFB4, PGAM2, PGD, PGK1, PGK2, PGM1, PPP2R5D, PRKAA1, PTGIS, RPE, STAT3, PDHX, OGT, KCNAB2, KYNU, TP53I3, HDAC4, COQ7, ECD |
2194 | GO:0006639 | 0.02 | 1.60 | 37.56 | 48 | 90 | acylglycerol metabolic process | ACLY, ANG, APOA1, APOA4, APOC2, APOH, C3, DAGLA, CAT, CAV3, CCNC, SCARB1, CETP, CPS1, DBI, ESR1, FABP2, FABP6, FABP7, ACSL1, ACSL3, ACSL4, G6PC, GK, GK2, GPD1, GPLD1, GPX1, INSIG1, LIPE, PCK1, PIK3CG, PPP1CA, PPT1, PRKACA, PRKACB, PRKACG, SLC25A1, SREBF1, ELOVL4, NR1H2, DGAT1, RGN, ACOT8, AGPAT2, ACOT2, SLC27A5, ACOT7 |
2195 | GO:0007166 | 0.00 | 1.60 | 160.25 | 206 | 420 | cell surface receptor signaling pathway | ABAT, ABCA1, ADA, AES, ANXA1, APC, ARNTL, ASGR2, BAG1, ADGRB2, BCL9, BSG, TSPO, C5, CACNA1F, CACNB4, CALCR, CBLB, CCNE1, CD2, CD3D, CD3G, CD9, CD36, CD37, CD38, CD53, CD59, CD79B, ADGRE5, CD151, CDA, CDK5, CHRNB2, CHRNB4, COL1A1, COL4A3, CR1, CR2, CSNK1D, CSNK1G2, CSNK1G3, CSNK2A1, CSNK2A2, CTLA4, CTNND2, DDB1, EDN3, EDNRB, CELSR2, ELF1, EMD, ADGRE1, SLC29A1, EVC, FCER1A, FCGR2A, FCGRT, FCN1, GPC4, FYB, GABRA4, GAS1, GCGR, GEM, GLP1R, GLRA1, GLRA2, GNAQ, GRK6, GRIA1, GRIA4, GRID1, GRID2, GRIK3, GRM1, GRM8, HIC1, PRMT1, ICAM2, IHH, ISL1, ITPKB, CD82, KCNN4, KLRB1, KLRD1, TACSTD2, SEPT2, NTSR1, P2RX3, P2RX4, P2RY1, P2RY2, P2RY4, P2RY6, P2RY11, PAWR, PDE4B, PDE4D, PRRX1, PPP3R1, RELN, PTCH1, PTH1R, PTH2R, PTK7, RB1, PRPH2, RFX4, RYK, SAG, SALL1, TSPAN31, SCTR, SDC1, SEMA3F, SFRP4, SFRP5, STIL, SIX3, SLAMF1, SLIT1, SMARCA4, SOX4, SOX10, SPN, STRN, TACR2, CNTN2, TSPAN7, TULP3, UBE2D2, UBE2V1, UPK1B, KDM6A, EZR, VIPR1, VIPR2, TRPV1, LAT2, WNT2, WNT11, WNT2B, ZIC1, FZD5, SEMA3B, FZD3, FZD6, FZD7, FZD8, FZD9, DYRK2, UNC5C, SSNA1, PTCH2, TNKS, IL18RAP, WISP1, LATS1, DGKI, GPR50, BCL7B, S1PR2, KLF4, GLP2R, NRXN1, HAND2, THEMIS2, RIMS2, SEMA3E, USP34, IFT140, KIAA0586, ZEB2, FARP2, P2RY14, FRAT1, HMGXB4, GPC6, TSPAN2, TSPAN1, G3BP1, ATP6AP2, CALCRL, APC2, ABCA7, CACNG2, SEMA3A, MAD2L2, UNC13B, SEMA6C, SEMA6B, SEMA4F, SEMA4B, KHDRBS1, PROKR1, MALT1, BRD8, IFT27, ADAP1, UPK1A, CD160, CORO1A, FZD10, GPR182 |
2196 | GO:0098661 | 0.05 | 1.60 | 25.04 | 32 | 60 | inorganic anion transmembrane transport | CFTR, CLCA1, CLCN2, CLCN3, CLCN5, CLCN7, CLCNKA, CLCNKB, GABRA4, GABRB2, GABRE, GABRG1, GABRR1, GABRR2, GLRA1, GLRA2, GLRB, SLC26A4, FXYD3, PTAFR, SLC4A1, SLC12A1, SLC12A2, SLC12A3, SLC12A4, SLC13A1, SLC34A1, SLC20A1, SLC20A2, BSND, SLC34A2, SLC26A1 |
2197 | GO:0001819 | 0.00 | 1.60 | 62.70 | 80 | 151 | positive regulation of cytokine production | ABL2, AGTR2, ANXA1, BIRC3, BCL3, C1QBP, CD2, CD4, CD6, CD14, CD28, CD80, CD86, TNFRSF8, CD58, CEBPG, CHUK, CLU, CSF2, CYBA, DHX9, EP300, EREG, F2R, F2RL1, FCER1A, FCER1G, FCN1, FGR, GATA3, IL10, IL12RB2, IL13, IL18, INS, IRAK1, PAEP, SERPINE1, PDE4B, PDE4D, PF4, PRG2, PRKCQ, PRKCZ, PTAFR, PTGER4, RARA, RPS27A, SEC14L1, SLC11A1, SOD1, SPN, STAT5B, SYK, TMF1, TRAF2, UBB, UCN, ZP3, FZD5, EPX, SEMA7A, IKBKG, RIPK1, IL1RL2, IL18R1, BCL10, ARHGEF2, IL27RA, PUM1, EBI3, PRG3, SPON2, AGPAT2, ARFGEF2, MALT1, GLMN, HHLA2, TREX1, TUSC2 |
2198 | GO:0050663 | 0.04 | 1.60 | 25.84 | 33 | 62 | cytokine secretion | ABCA1, ABL2, AGTR2, ALOX15B, C5, CASP5, CD2, CD14, CD36, CD58, CHI3L1, CRP, F2R, FCN1, FGR, GATA3, IFNG, RBPJ, IL1A, IL1B, INS, P2RX7, PAEP, PRKCZ, RAB1A, S100A12, S100A13, SYK, TWIST1, IL1RL1, ATG5, TRIM16, GLMN |
2199 | GO:0044087 | 0.00 | 1.59 | 62.76 | 80 | 152 | regulation of cellular component biogenesis | ACVRL1, ADD1, ARHGAP6, BLK, BRCA1, CAPZA1, CHRNB2, CLDN7, ACE, DDX3X, S1PR1, EIF4EBP1, EPHA3, EPHA7, EPS8, GFAP, GHSR, GPM6B, RAPGEF1, HCLS1, DNAJB2, HSPA8, HSP90AA1, INS, INSIG1, LCAT, SMAD6, PARK2, CHMP1A, PEX14, PPM1A, PRKAA1, PRKACA, PRKCZ, EIF2AK2, PTGER4, PEX5, RAF1, RAP1A, RB1, REST, SELP, SGK1, SIX1, SLC9A1, SLIT1, SNAI2, SMPD2, SNAI1, SNCA, SORL1, SPTA1, SPTB, STXBP1, TBCD, TMOD1, TNFRSF1A, VDAC2, EZR, ALMS1, FZD5, RAB7A, STAM, NSMAF, LATS1, RAB33A, BAG5, SNCAIP, FEZ2, RAPGEF2, SLK, FARP2, SEC24B, RBM14, ARFGEF1, PDLIM5, AVIL, STMN2, SNF8, ATXN2L |
2200 | GO:0051494 | 0.03 | 1.59 | 32.97 | 42 | 79 | negative regulation of cytoskeleton organization | ADD1, APC, SHROOM2, ARHGAP6, BBS4, BRCA1, CAPZA1, CAPZB, CAV3, CCNB1, S1PR1, EPS8, TACSTD2, NUBP1, PARK2, PFN1, PFN2, RDX, SGK1, SNCA, SPTA1, SPTB, AURKA, TBCD, TMOD1, VIL1, ARHGEF2, AURKB, SLIT2, PICK1, GMFG, HDAC6, WASF2, APC2, KATNB1, RBM14, ARFGEF1, GAS2L1, AVIL, STMN2, CORO1A, TWF2 |
2201 | GO:0033036 | 0.00 | 1.58 | 601.15 | 738 | 1450 | macromolecule localization | ABAT, ABL2, ACHE, ACTN4, ACTL6A, ACVR2B, ADAR, ADORA1, ADRA2C, AP2A1, AP2B1, AP1G1, NR0B1, ALOX15B, ANG, ANGPT1, SLC25A4, ANXA2, ANXA4, ANXA5, APBB1, APC, BIRC5, SHROOM2, ARF1, ARF4, ARL4D, ARF5, ARF6, ARHGDIG, ARL1, ARL2, ARNTL, ASNA1, ATM, RERE, ATP1B3, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, ATR, ATRX, AZGP1, BAD, BARD1, BAX, BBS1, BBS2, BBS4, BCL2, BCL2L1, BCL3, BICD1, BID, BLK, BMP4, BMPR1A, BNIP3L, BRCA1, BRCA2, BSG, BTF3, BUB1B, C5, CACNA1A, CACNA1E, CALCR, CAMK4, CAMK2G, CASP5, CASP8, CAV3, CBLB, CCNB1, CD2, CD3G, CD4, CD14, SCARB2, CD38, CD40, CD58, CD63, CD74, CDC42, CDH1, CDK5, CDKN1A, CDKN2A, CENPA, CENPF, CHI3L1, CHRM1, CHRM3, AP2M1, AP1S1, AP2S1, AP3S1, CLTA, CLTC, CNR1, COL1A1, COPA, COPB1, CSNK1D, CSNK2A2, CTNNA1, CTSK, CYLD, DAB2, DBN1, DDX1, DDX3X, DHX9, DHCR24, DIAPH1, DLG1, DLG2, DLG3, DMBT1, DNM2, DNMT3B, DPP6, DSP, ECT2, EDA, EFNA5, CELSR2, EGR2, EPHA2, EIF4E, EIF5A, EMD, EMP2, CTTN, ENSA, STOM, EPHA5, EPS15, ERBB2, ERCC3, ETV5, EYA1, F2R, F2RL1, FBLN1, FAU, FBN1, FCER1G, FCN1, FGA, FGF7, FGF9, FGG, FGR, FLNA, FLOT2, FNTA, NR5A1, FYB, FYN, GAS6, GAS8, GATA3, GCG, KAT2A, GDI1, GDI2, GFER, GHSR, GIP, GJA5, GLE1, GLP1R, GLRB, GLUD1, GLUL, GNAQ, GNAS, GNGT1, GOLGA1, GOLGA4, SFN, GPLD1, GPM6B, GPR26, GPR27, FFAR1, GRID2, GRIN2A, GUK1, HIST1H1B, HCLS1, NRG1, HHEX, HIF1A, HK2, HMGCR, FOXA2, AGFG1, HES1, DNAJB2, HSPA4, HSPA8, HSPA9, HSP90AA1, HSP90AB1, IFIT1, IFNA2, IFNG, IGF1, RBPJ, IL1A, IL1RN, IL10, IL13, TNFRSF9, IL18, INS, ISL1, ITGA2, ITGA3, ITGA4, ITGAL, ITGAX, ITGB1, ITPR1, ITPR2, ITPR3, JUN, JUP, KCNA1, KCNA5, KCNE1, KCNJ11, KCNS3, KIF5A, KPNA1, KPNB1, KPNA4, KPNA5, TNPO1, IPO5, KRT18, LAMA5, LAMP2, LLGL2, LTBP1, LTBP2, SMAD3, SMAD7, MAL, RAB8A, ATXN3, NUBP1, SEPT2, RPL10A, TONSL, SLC11A2, NRAS, NRCAM, YBX1, NUP88, NUP98, OAZ1, OAZ2, OGG1, OR1D2, OXA1L, OXCT1, P2RY1, PAEP, PAM, PCM1, CHMP1A, PCSK1, PCSK5, CDK16, PDE3B, PDE4C, PDPK1, SLC26A4, PEX1, PEX6, PEX10, PEX12, PEX14, PFKFB2, PIGR, PIK3C3, PPID, PPM1A, PPM1B, PPP3R1, PPT1, SRGN, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCB, PRKCE, PRKCI, PRKCQ, PRKCZ, MAPK3, MAPK8, RELN, PSMB7, PSMD8, PTGER4, PTN, PTPN1, PTPN14, PTPRN, PTPRN2, PEX19, PEX5, RAB1A, RAB3A, RAB3B, RAB4A, RAB6A, RAB13, RAB27A, RAB27B, RABIF, RAB5C, RAC1, RAC2, RAF1, RAN, RANBP2, RAP1A, RAP2A, RB1, RDX, REST, RFX3, RNASE2, RPGR, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, CLIP1, RTN2, RYR2, S100A10, S100A12, S100A13, CX3CL1, SDCBP, SEL1L, SFRP5, SRSF1, SRSF2, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, STIL, SIX1, SIX3, SLC2A2, SLC9A1, SLC11A1, SLC12A1, SLC15A1, SLC15A2, SLC16A1, SNAI2, SUMO3, SNAP25, SOX4, SOX9, SP100, SPAG4, SREBF1, SRP9, SRP14, SRP19, SRP68, SSR1, SSR3, STAT3, STAU1, AURKA, STK11, STXBP1, STXBP2, STXBP3, STYX, ABCC8, TACR2, CNTN2, HNF1A, DYNLT1, TNFAIP2, TNFAIP3, TNFRSF1A, TRAF2, TRH, CCT3, TRIP6, TRPM2, TRPS1, TSC1, TSC2, TSG101, TST, TULP1, TULP2, TULP3, TWIST1, TNFSF4, TNFRSF4, U2AF1, UBE2L3, SUMO1, UFD1L, UGT8, USP4, USH2A, VCL, VEGFA, VEGFC, VIL1, EZR, VIP, VSNL1, WHSC1, WNT11, WRB, YWHAG, YWHAH, YWHAZ, ZIC1, ZBTB17, ZP2, ZP3, FZD5, SCG2, RAB7A, ARHGEF5, NUP214, STAM, CUBN, CSRP3, AAAS, IFT88, AKAP1, MADCAM1, CLTCL1, UBL4A, PICALM, BAP1, FZD7, NR0B2, DYRK2, OGT, CNTNAP1, KCNAB2, ITGA8, CAMK1, AP3B1, BLZF1, PRPF18, KHSRP, USO1, CADPS, SSNA1, AKR1C3, NUMB, DYNLL1, TNKS, VAMP8, STX16, STX11, STX10, BECN1, SRSF9, TNFSF14, ADAM9, RAB11A, SNAP23, IL18R1, LIN7A, IQGAP1, HDAC3, AKAP4, AP1S2, AP1M1, HERC2, AP3D1, SELENBP1, ATP6V0E1, HAP1, RPL14, AIP, MAP7, SYT7, LATS1, ATP6V0D1, SEC22C, RABEP1, IL1RL1, AP4M1, ARHGEF2, RASSF9, ZW10, AURKB, VAPA, RAB11B, ITGB1BP1, COPB2, ATP6V1F, TRIP11, HMGN3, SNAP29, TAOK2, RPL23, CER1, RAB33A, RAB9A, ZFYVE9, NRXN1, NRXN2, COG1, PEX16, CRIPT, QKI, EIF2AK3, PICK1, AKAP7, AKAP6, ATG5, CABP1, STXBP5L, LITAF, GOSR1, TMEM59, BAG4, RAB3D, APBA3, ATP6V1G1, SEC22B, VPS26A, GOSR2, NR1D1, CLOCK, CARTPT, RAB36, NUP155, IPO13, NUP93, RAPGEF2, CROCC, TRAM2, RIMS2, CEP57, IFT140, ACAP1, ZFYVE16, SNX17, DHX38, KIAA0586, SPCS2, CKAP5, IST1, TOMM20, C2CD5, KIAA0753, C2CD2L, SMG7, SNAP91, KIAA0196, RABGAP1L, SUPT7L, FAM20B, DOPEY2, HDAC6, PDCD6IP, PDCD6, BCL2L11, PIGK, PARP3, TOM1L1, TOM1, AP1M2, SCAMP2, PTPRU, KIF20A, PREB, ARFRP1, TRIM28, ALYREF, CALCRL, NUTF2, DDX39A, STX6, AP3S2, STAM2, RAMP2, RAMP3, APC2, KATNB1, IKZF1, TRIM22, RAPGEF3, ARIH2, SEC24B, TOMM40, TACC3, COG5, NXF1, SEC23B, SEC23A, CREB3, APPBP2, FBLN5, CHERP, ATG7, AGR2, ARFGEF2, ARFGEF1, CCT7, CCT4, CCT2, SORBS1, TRIM3, RBCK1, TRIM16, TXNIP, EXOC5, IGF2BP3, KHDRBS1, RRAGA, TNFSF13B, CCT6B, CCT8, AP4B1, SIX2, GIPC1, TRAF3IP2, NUP50, AHCYL1, SRSF10, VAMP5, SEC24A, CPLX1, RUVBL2, EDAR, RNPS1, KDELR1, AP3M2, SEC61B, TOMM34, OS9, ERP29, RAB40B, TMED10, FERMT2, RAB32, KDELR3, IFT27, RAB35, RBPMS, RAB31, WWP2, RAPGEF4, TMEM115, RER1, NUPL2, CAPN10, CDC37, GLMN, WDR45, AP4S1, AKAP10, RPL35, PRAF2, SEC63, XPOT, SNF8, DDX19B, COPE, DDX42, PHB2, GABARAP, TWF2 |
2202 | GO:0032107 | 0.04 | 1.58 | 28.35 | 36 | 68 | regulation of response to nutrient levels | ACTL6A, ADRB2, BNIP3, BNIP3L, TSPO, CSNK2A2, CTSK, CYP27B1, DCN, CTTN, ERN1, KAT2A, HIF1A, KDR, PAFAH1B2, PARK2, PIP4K2A, RPL28, SNAI2, SREBF1, TSC1, U2AF1, ZBTB17, FZD5, RAB7A, EPM2A, IFT88, BECN1, TRIM24, RAB33A, ATG5, FEZ2, RUBCN, HDAC6, ATG7, SPTLC1 |
2203 | GO:0070588 | 0.04 | 1.58 | 29.92 | 38 | 72 | calcium ion transmembrane transport | ANXA5, ATP2A1, ATP2B1, ATP2B2, CACNA1A, CACNA1B, CACNA1E, CACNA1F, CACNA1S, CACNA2D1, CACNG1, CCR5, GAS6, GPM6A, XCR1, GRIN2A, HTR2C, ITGAV, ITPR1, ITPR2, ITPR3, P2RX7, RYR1, RYR3, CCL21, SLC8A3, TRPC3, TRPC4, TRPC5, TRPM2, TRPV1, ZP3, CUL5, SLC24A1, CACNG2, CHERP, CACFD1, IL1RAPL1 |
2204 | GO:0034248 | 0.00 | 1.58 | 90.98 | 115 | 218 | regulation of cellular amide metabolic process | AARS, ACO1, ADAR, AKT2, ANG, ATF4, BCL3, BPGM, C1QBP, CD28, CDK4, CIRBP, CLU, DAZ1, DDX1, DDX3X, DDX6, DIO2, EEF2, EIF2S1, EIF2B1, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4EBP1, EIF4EBP2, EIF4G1, EIF4G2, EIF5, EIF5A, ELAVL1, EPRS, ERBB2, FECH, GAPDH, GRB7, HSPB1, IGF1, IGFBP5, EIF3E, IREB2, ITGA2, CAPRIN1, SMAD1, SMAD3, CNOT2, PA2G4, PER1, PGAM2, PPP1CA, PRKAA1, MAPK3, EIF2AK2, DNAJC3, PTAFR, PURA, RAN, RARA, RBM3, RBM4, RGS2, RPL38, RPS3, RPS4X, RPS6KA1, RPS6KA3, RPS6KB2, RXRA, S100A9, SMPD2, SORL1, SOX4, SRP9, TARBP2, TNFRSF1A, TSC1, UCN, EIF4H, ZFP36, PICALM, NSMAF, MAPKAPK5, PRKRA, EIF3A, EIF3B, EIF3D, EIF3F, EIF3G, EIF3J, CDC123, EIF2B4, EIF2B3, EIF2B2, EIF2B5, HAP1, RQCD1, CNOT8, QKI, EIF2AK3, EIF5B, PUM1, CTIF, NR1H4, TRAP1, EIF1, EIF1B, ABCA7, PRG3, OLFM1, EIF3M, USP16, IGF2BP3, KHDRBS1, TMED10 |
2205 | GO:0048589 | 0.02 | 1.58 | 35.40 | 45 | 86 | developmental growth | ADD1, ATRX, BMPR1A, BRCA2, CDC42, DHCR7, DMBT1, EN1, ERCC1, ERCC6, G6PC, GAMT, GAS1, GATA3, KAT2A, GNAS, GPD2, HHEX, HOXD11, IGFBP5, IHH, LLGL2, SMAD3, PDE4D, PTCH1, RAD51B, RBBP6, STIL, SOX10, SP2, STAT3, TARBP2, TBCE, TYMS, KDM6A, EIF4H, XPA, XRCC2, ATRN, HDAC3, SGPL1, GINS1, SETDB1, KLF2, RAI1 |
2206 | GO:0080135 | 0.00 | 1.57 | 79.80 | 101 | 193 | regulation of cellular response to stress | ACTL6A, ADRB2, APBB1, ARNTL, BAX, BCL2L1, BDKRB2, BMPR1A, BNIP3, BNIP3L, BRCA1, TSPO, CASP9, CD44, CD74, CDK6, CDK9, CDKN2A, CDKN2D, CEBPG, CLU, CRY1, CSNK2A2, CTSK, DCN, DDX5, DYRK1A, CTTN, EYA1, EYA3, FECH, KAT2A, GRINA, HIC1, HMGA1, ING2, KCNK2, KDR, MGMT, ATXN3, NTRK3, OGG1, OPA1, PAFAH1B2, PIP4K2A, PRRX1, PPP4C, PRKCG, DNAJC3, RAD51, RPL28, SETMAR, SGTA, SNAI2, SNAI1, SREBF1, TNR, TPT1, TSC1, TWIST1, U2AF1, UBE2V1, UBE2V2, WFS1, WHSC1, ZBTB17, RAB7A, EPM2A, IFT88, CUL4A, OGT, TP63, BECN1, USP13, RNF8, USP14, ARHGEF2, KLF4, TRIP12, RAB33A, EIF2AK3, ATG5, BRE, FEZ2, RUBCN, BCLAF1, NUAK1, BCL2L11, FEM1B, TRIM28, CREB3, ATG7, AGR2, SPTLC1, RAD51AP1, USP19, SERINC3, OS9, ERP29, ZNF277, CHEK2 |
2207 | GO:0042981 | 0.03 | 1.57 | 32.12 | 41 | 81 | regulation of apoptotic process | ACTN4, ACTN1, ALK, ALX3, BMP1, BMP6, BMP8B, BTK, CASP4, CASP5, CASP10, CD3G, ESR1, ETS1, FLT3, GAS1, GDF9, GRID2, TNFRSF9, INHA, TNFRSF11B, PHB, SKP2, STK10, TNFRSF1A, TNFRSF1B, TNFRSF4, WRN, TRIM24, BMP15, TAOK2, GDF15, BCAR1, TRAF4, SLK, OXSR1, SRA1, SGK2, SIGMAR1, STK25, MAP4K5 |
2208 | GO:0051345 | 0.00 | 1.56 | 186.07 | 233 | 447 | positive regulation of hydrolase activity | ABL2, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADCYAP1R1, ADRBK1, AKT2, ALDH1A1, ALOX12, AMPH, ANG, APOA1, APOA4, APOC2, APOH, ARF4, ARHGAP4, ARHGAP5, ARHGAP6, ARHGDIB, ARHGDIG, ARL1, AVPR1B, BAD, BAX, BID, BNIP2, BOK, CAMK4, CASP8, CASP9, CAV2, CCK, CD14, CD40, CDKN2A, RCBTB2, CHN1, CHN2, COL4A3, CR1, CTGF, DDX3X, ECT2, S1PR1, LPAR1, EDNRA, EIF2B1, EPHA2, EPHA1, ERBB2, ERN1, ESR1, F2R, F3, FBLN1, FGD1, FGFR3, FLT1, FNTA, GCGR, GDI1, GDI2, GM2A, GNA15, GNAQ, GNAS, GNAT1, FFAR1, RAPGEF1, ARHGAP35, HIP1, AGFG1, AGFG2, ICAM1, IFI16, ITGA6, ITGB1, ITPR1, ITPR2, ITPR3, JUN, KIT, LLGL2, MAP3K5, SLC11A2, NTF3, NTRK1, NTRK3, OCRL, OPHN1, PCOLCE, PDE1B, PDPK1, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCE, PRKCG, PRKD1, PRKCZ, MAPK8, PSME1, PSME2, PTAFR, PTPN1, RABIF, RAP1A, RAP1GAP, RAP1GDS1, RASA2, REST, RGS1, RGS2, RGS10, RGS13, RGS16, RPGR, RPS3, RSU1, S100A8, S100A9, S100A10, SBF1, SERPINB3, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SELE, SEMG1, ITSN1, SIPA1, SNCA, SOS1, SOS2, CDKL5, XCL2, TBCD, TRAF2, TRIO, TSC1, TSC2, NR1H2, VAV1, VEGFA, WNT11, WRN, ARHGEF5, PICALM, BCAR3, MADD, S1PR4, TRADD, RIPK1, CRADD, TNFSF10, RGS11, RGS9, TNFRSF10B, TNFRSF10A, IQGAP1, CFLAR, ASAP2, ARHGEF7, EIF2B4, EIF2B3, EIF2B2, EIF2B5, BCL10, HERC2, KALRN, AIFM1, RABEP1, ARHGEF2, VAPB, CYTH3, CYTH2, GPR55, TRIP10, ARHGAP29, EIF2AK3, ARHGEF6, STXBP5L, RIN1, RAPGEF2, USP6NL, ACAP1, RAPGEF5, RGP1, ARHGEF17, FARP2, SGSM2, DENND4B, RABGAP1L, ARHGAP25, TNFSF15, CASP8AP2, PDCD6, BCL2L10, BCL2L11, SH2D3C, SH2D3A, RASA4, FARP1, PSME3, RASGRP2, DENND4A, CDC42EP2, VAV3, CREB3, ARL6IP5, CXCL13, ARFGEF2, ARFGEF1, CDC42EP3, RGS14, ADAP1, ADRM1, RAPGEF4, CDC42EP1, FZD10, AKAP13 |
2209 | GO:0032502 | 0.00 | 1.56 | 102.50 | 132 | 291 | developmental process | A2M, ACO1, ADCYAP1R1, AP1G1, ALDH3A1, ATP5G3, ATR, TNFRSF17, BLK, BRDT, BST2, SERPING1, CCIN, TNFRSF8, CENPE, CLCN3, CLPS, CLTC, ACKR2, COMT, CYLC1, CYP24A1, DAZ1, DDC, DDX1, DHX9, EBF1, PHC1, PHC2, EIF2S1, ELF1, ELK1, ERCC6, ETV3, FLII, FRK, G6PC, GAS1, GNRH2, GNRHR, HIST1H1T, HIC1, HIP1, HIVEP2, HMX1, IDE, IGFBP2, TNFRSF9, INSL4, INSRR, IRAK1, ITPR1, KRT33B, ALDH6A1, DRG1, ODF1, OGG1, PAEP, PCOLCE, PHB, PIM1, PTGDR, PTGS1, RGS2, RPL29, RPN2, RPS3A, RPS4X, RPS4Y1, RPS11, SLC2A4, SNCA, SOD2, SPIB, SRMS, SUV39H1, SYP, TACR3, TNFRSF1B, TNP2, TRO, TNFRSF4, TYK2, UBE2V1, UCP1, SCGB1A1, EIF4H, XPA, ZFX, ZNF3, ZNF7, ZNF45, ZNF74, PRDM2, PTP4A1, LTBP4, SOAT2, FKBP6, MAPKAPK5, TNK1, TNFRSF6B, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, PEX11A, CREG1, AP1M1, RQCD1, DDX21, AURKB, BCL7B, KIF3B, RECQL4, LITAF, NR1D1, PUM1, UTP14C, SPATA2, NUAK1, NR1I3, DOPEY2, SRA1, HDAC6, ARL4A, TNK2, ALYREF, APC2, FAM3C, RAB32, ZNF277, CHEK2 |
2210 | GO:0042592 | 0.02 | 1.56 | 35.34 | 45 | 89 | homeostatic process | ANG, APC, KRIT1, CFL2, CLCN6, CLNS1A, DLD, E2F4, FEN1, GAA, IDE, KCNN4, SMAD1, PRIM1, PRIM2, RAD51, RAD51D, RAG2, RFC1, RFC2, RFC3, RFC4, RFC5, RPA3, SLC12A4, SP100, TYRO3, WRN, TUSC3, HIST1H4I, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, AIFM1, DCLRE1A, PARP3, PDIA6, PRDX4, PDIA5 |
2211 | GO:0045892 | 0.00 | 1.56 | 79.21 | 100 | 193 | negative regulation of transcription, DNA-templated | BIRC5, ARNTL, BCL3, BCL7A, BRCA1, RUNX2, RUNX1T1, CD38, CDK5, CENPF, DAB2, ELF3, ELK3, EREG, FOXD1, HIST1H2AE, HIST1H2AD, H2AFZ, H3F3B, NRG1, HMGA1, HSPA8, IFNA2, IRF1, CITED1, PA2G4, PAX2, PAX9, CHMP1A, ATP8B1, PHF2, PSMC5, PURA, ARID4A, RFX3, SET, SIX3, SMARCE1, SOX5, SOX9, SOX10, TBP, TSG101, UBTF, WNT11, ZIC2, ZNF91, ZNF224, ZP3, KDM5C, HIST1H4I, CDC45, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, ZNF282, HAT1, TRIM24, HESX1, NR1I2, HIST1H3F, HIST1H2AG, TAF1C, TAF1B, TAF1A, UBA3, BTAF1, CBFA2T2, RPS6KA5, CIR1, CLOCK, KDM4A, BCLAF1, NR1I3, NR1D2, HDAC6, ZNF263, YAF2, RAMP3, DEAF1, ERN2, KHDRBS1, ARID5A, CCDC85B, WWP1, BAZ2A, CBX3 |
2212 | GO:0048193 | 0.01 | 1.56 | 58.69 | 74 | 141 | Golgi vesicle transport | AREG, ARF4, ARL1, BGLAP, CD59, COPA, COPB1, CSNK1D, CTSZ, CUX1, CD55, DYNC1H1, DYNC1I1, DYNC1I2, F7, F10, GAS1, GAS6, GOLGA1, GOLGA2, GOLGA3, GOLGB1, GRIA1, INS, INSIG1, LMAN1, RAB8A, PPP6C, PRKCI, PRKD1, PROC, PROS1, RAB1A, RAB6A, SPAST, SPTA1, SPTB, TRAPPC10, UVRAG, CUL3, USO1, DYNLL1, PROZ, SEC22C, ZW10, VAPB, VAPA, CYTH3, COPB2, TRIP11, COG1, PICK1, GOSR1, SEC22B, GOSR2, SGSM2, GOLGA5, ATP9A, PREB, STX6, ATP8A1, SEC24B, COG5, SEC23B, SEC23A, DCTN6, SEC24A, KDELR1, TMED10, RAB35, TMEM115, RER1, DCTN3, COPE |
2213 | GO:0009058 | 0.00 | 1.56 | 182.36 | 230 | 478 | biosynthetic process | ABO, PARP4, ALDH2, SLC25A4, ART1, DAGLA, SLC25A20, CD59, CDC25C, CDKN2D, CKM, COMT, COPA, COPB1, COX4I1, COX5B, COX6A1, COX6B1, COX7B, COX7C, COX8A, CSNK1D, CSTF3, CTSZ, DAD1, CD55, DAO, DARS, DBH, DDC, DIO1, DIO3, DYNC1H1, DYNC1I1, DYNC1I2, DNTT, EEF1A2, EEF1B2, EIF1AX, EIF2S3, FAU, FUT6, GAD2, GALNT1, GK2, GOLGB1, SFN, GPX2, GRIA1, GTF3C1, GTF3C2, IL1RAP, IL18, STT3A, KCNE1, LMAN1, MGAT5, NUBP1, DRG1, RPL10A, NUP88, NUP98, OAZ1, OAZ2, ORC5, PCSK1, PCSK5, CFP, PPM1B, PPP5C, PPP6C, PRKCSH, PTMA, RAD1, PYGL, QARS, QDPR, RAB1A, RAD51, RBMS1, RHEB, RPL3L, RPL4, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL36AL, RPL37, RPL37A, RPL39, RPL36A, RPN2, RPS2, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS28, RPS29, SAT1, SEL1L, SETMAR, SRSF1, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SLC2A4, SLC22A2, SMS, SNRPE, SNRPF, SPTA1, SPTB, SRP14, SRP19, SRP68, SSR1, SSR3, TARS, TAT, PRDX2, TRAPPC10, TOP1, U2AF1, UGT2B4, UGT2B7, VEGFB, WRN, YWHAG, YWHAZ, AIMP2, TUSC3, NUP214, SLC25A16, AAAS, CDK2AP1, DENR, USO1, DDX3Y, SRSF9, GALNT4, RNGTT, EIF2S2, SLC25A14, RPL14, EIF1AY, CCNE2, COX7A2L, DDX21, COPB2, GTF3C5, GTF3C4, GTF3C3, RPL23, COX5A, COG1, RECQL4, ATG5, GOSR1, SEC22B, GTPBP1, GOSR2, NUP155, NUP93, DHX38, SPCS2, PARP2, PARP3, ABCB6, NUBP2, CHST4, SPON1, SEC24B, COG5, SLC25A17, SEC23A, ATG7, RNASEH2A, IVNS1ABP, SPHAR, FARS2, RRAGA, DCTN6, FUT9, NUP50, ALDH1L1, PAPOLA, RNPS1, DBF4, UGT2A1, KDELR1, SEC61B, OS9, TMED10, PAPD7, ADRM1, TMEM115, HSF2BP, ADAMTS13, ADAMTS5, NUPL2, WDR45, ADAMTS7, RPL35, DCTN3, TREX1, COPE |
2214 | GO:0003008 | 0.00 | 1.56 | 407.91 | 504 | 986 | system process | SERPINA3, AARS, ABAT, ABCA4, ABL2, ACO1, ACTA2, ACVRL1, ADA, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADK, ADORA2A, ADRA1B, ADRA2C, ADRBK1, ALDH1A3, ALOX12, AMPH, ANGPT1, ANXA1, ANXA2, ANXA6, AOC2, APLP2, APOA1, APOA4, ARF4, ARG2, ARR3, STS, ATP1B3, FXYD2, ATP2A1, ATP2B1, ATP2B2, ALDH7A1, AZGP1, BBS1, BBS2, BBS4, BCHE, BCL2, OPN1SW, BDKRB2, BMP4, BMPR2, BRS3, SERPING1, CA6, CACNA1A, CACNA1B, CACNA1E, CACNA1F, CACNA1S, CACNA2D1, CACNB4, CACNG1, CALM3, CAMK4, CAMK2G, CASQ2, CAV3, CCK, CD36, SCARB1, CD38, CDC42, CDH3, CDK5, CDK9, CDKN2D, CHRM1, CHRM3, CHUK, TPP1, LTB4R, CNGA1, CNGA2, CNN1, CNR1, CNR2, COL1A1, COL2A1, COL4A3, COL11A1, COPA, CPS1, CRP, CRX, CRYAB, CRYBA1, CRYBA4, CRYGB, CRYM, CRYZ, CST1, CTGF, CTNNA2, CTNS, CTNND2, CX3CR1, CXADR, CYP11B1, DBH, DBI, DFNA5, COCH, CYB5R3, DIAPH1, DLG1, DLG2, DNM1, DPP6, DSC2, RCAN1, DSP, DTNA, HBEGF, E2F4, S1PR1, EDNRA, EEF2, EGR2, EIF4EBP2, ELN, EMD, EMP2, CTTN, EPB41, EPHB1, EYA4, EYA1, EYA3, FABP7, EFEMP1, FEN1, FGA, FGG, FLI1, FLT1, AFF2, FYN, GABRB2, GABRR2, GAMT, GAS6, GATA4, GATA6, GCGR, OPN1MW, GDNF, GHSR, GIP, GJA3, GJB2, GLP1R, GLRB, GM2A, GNAL, GNAS, GNAT1, GNAT2, GNB1, FFAR3, GPX1, GRIA1, GRID2, GRIN2A, ARHGAP35, GRM1, GRM8, GSTM2, GTF2I, GUCA1A, GUCA1B, GUCY1B3, GUCY2F, GUCY2D, HAS2, HEXB, HGF, NRG1, HIF1A, HMGCR, HOXC10, HPN, HPS1, HRH1, HRC, HRH2, HSBP1, HTR2C, IAPP, ICAM1, IFNG, IGF1, IGF2, IGFBP5, IL10, IMPG1, INS, ITGA1, ITGA2, ITGA3, ITGA5, ITGB1, ITGB5, ITPR1, ITPR2, ITPR3, JUN, JUP, KCNA1, KCNA2, KCNA5, KCND2, KCND3, KCNE1, KCNJ2, KCNJ8, KCNJ10, KCNJ11, KCNJ12, KCNJ14, KCNK2, KCNK3, KCNN4, KCNQ1, KIT, ABLIM1, LUM, TACSTD2, SMAD7, MAN2B1, MEOX2, PPP1R12B, SLC11A2, NRCAM, NRL, NTF4, NTRK1, NTRK2, NTS, NTSR1, OAT, OLR1, OMP, OPA1, SIX6, OR1D2, OR1F1, OR2C1, OR3A1, OR3A2, P2RX3, P2RX4, P2RX7, P2RY1, P2RY2, PARK2, PAWR, PAX2, PDCL, PDC, PDE3A, PDE4A, PDE4B, PDE4D, PDE6G, PDE6H, PDE1B, SLC26A4, SERPINF1, PENK, ATP8B1, PGAM2, SERPINB6, PIGR, PIK3C2A, PIK3CG, FXYD3, PLN, PPT1, PRCP, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCG, PRKCQ, PRKCZ, PRKG1, MAPK3, RELN, PTAFR, TAS2R38, PTGS1, PTN, PTPRJ, PTPRM, PTPRZ1, RABGGTA, RABGGTB, RAC3, OPN1LW, RCVRN, PRPH2, RGR, RGS2, RGS16, RLBP1, RNPEP, RP9, RPGR, RPL38, RS1, RYR1, RYR2, RYR3, S100A1, S100B, SAG, ACSM3, ATXN7, SCN1A, SCN2B, SCN3A, SCN4B, SCN5A, SCN8A, SCN10A, SCNN1A, SCNN1D, CX3CL1, SFRP5, SRSF1, SGCD, SGK1, SHC1, SIX1, SIX3, SLC2A5, SLC6A4, SLC6A8, SLC8A1, SLC8A3, SLC9A1, SLC12A2, SLC22A5, SLN, SNAI2, SNAP25, SNTA1, SNTB1, SOD1, SOD2, SOX2, SOX9, SP4, SREBF1, SRF, SSTR2, XCL2, TACR3, CNTN2, TAZ, TBCE, TBL1X, HNF1A, ZNF354A, NR2E1, TMOD1, TNNC2, TNNI2, TNNI3, TNNT1, TNNT2, TNR, TPM2, TRPC1, TRPC3, TULP1, TULP2, SUMO1, COL14A1, NR1H2, USH2A, CLRN1, VCL, VDR, VEGFA, VEGFB, VEGFC, VIL1, EZR, VIM, VIP, VIPR1, WFS1, ZIC2, EPM2A, TUSC3, CSRP3, FOSL1, AAAS, AKAP1, DYSF, FZD9, OR1A1, OR1E1, OR1E2, OR1G1, OR3A3, SOX14, BFSP2, SOAT2, SORBS2, CNTNAP1, KCNAB2, ITGA8, CYP4F2, OR6A2, AKR1C3, PDE5A, RAB11A, RGS9, CFLAR, KAT2B, STBD1, TAAR5, CTDP1, DGKI, SLC24A1, DHRS3, ITGB1BP1, GPR52, KLF4, SLIT2, SLC22A6, NRXN3, NRXN1, NRXN2, KCNK6, GSTO1, EIF2AK3, AKAP6, ATG5, IGDCC3, CARTPT, RIN1, GUCA1C, NUP155, KDM4A, FAM65B, HDAC4, FIG4, RNF10, WDR1, DOPEY2, KCNE2, NR2E3, HCN4, ABCC9, COL4A3BP, AKAP9, SORBS3, CALCRL, RCAN2, KCNMB2, IRX5, RAMP2, RAMP3, TRDN, ABCA7, CACNG2, SEMA3A, ATP8A1, DEAF1, ATG7, SORBS1, PDLIM5, RGS14, RRH, TBR1, CHL1, AHCYL1, OR5I1, GJB6, UGT2A1, KERA, KPTN, BVES, STRAP, AKAP13, HRH3, SCN11A |
2215 | GO:0048284 | 0.04 | 1.56 | 31.72 | 40 | 76 | organelle fusion | ADRB2, AKT2, ANXA1, ANXA2, BAX, BCL2A1, BNIP3, CAV2, GNAI3, LRMP, RAB8A, OPA1, PARK2, RAB3A, SLAMF1, SNAP25, STXBP1, SYT1, SYT4, TSG101, UVRAG, RAB7A, DYSF, EEA1, USO1, VAMP8, STX16, STX11, STX10, SNAP23, SEC22C, SNAP29, GOSR1, SEC22B, RUBCN, C2CD5, STX6, VAV3, VAMP5, CORO1A |
2216 | GO:0048609 | 0.00 | 1.56 | 146.78 | 184 | 354 | multicellular organismal reproductive process | ACOX1, ACVR1, ADCYAP1R1, ADRB2, NR0B1, AHR, ANG, ANXA1, BIRC3, ARNTL, ATM, ATRX, AXL, BAD, BAX, BBS2, BBS4, BCL2, BCL2L1, BIK, BMP4, BRCA2, BRDT, BTG1, CAPN5, CCIN, CCNB1, CCNE1, CDC25C, CFTR, CLU, COMT, CTNNA1, CXADR, CYLC1, DAZ1, DBH, ACE, DIAPH2, DLD, DNM2, DNMT3A, PHC2, CELSR2, ERCC1, ETS1, ETV5, FANCC, FANCD2, FANCG, FGF7, CENPI, FSHR, NR5A1, B4GALNT1, GAMT, GATA4, NR6A1, GDF9, GHRHR, GNAQ, GRN, HIST1H1T, HIST1H1A, HAS1, HAS2, AGFG1, ICAM1, IGF1, IGF2R, ING2, INHA, INSL3, KDR, KISS1, KIT, LIMK2, SMAD1, MEA1, KITLG, ODF1, ODF2, CLDN11, OVOL1, PAFAH1B2, PAFAH1B3, SERPINA5, CDK16, PDE3A, SERPINF1, PGAM2, PPP2R1A, PRKACA, PRKACG, PRM2, PTAFR, PTGER4, PTN, PTPRN, RARA, ARID4A, RGS2, RNF2, RPS6KA2, SBF1, SEMG1, SIAH1, SLC6A4, SLIT3, SMARCA2, SMARCA4, SOD1, SOX3, SOX9, SPAG4, SSTR2, SSTR3, STAT5B, AURKA, STK11, STYX, TAC1, TAF4B, TARBP2, TBP, TMF1, NR2C2, TRPM2, TSPY1, TYRO3, UBE3A, VEGFA, ZNF35, ZNF148, ZP3, FOSL1, IFT88, USP9X, USP9Y, FZD4, FKBP6, DDO, TP63, PDE5A, DYNLL1, SGPL1, EIF2B4, EIF2B2, EIF2B5, EIF2S2, HERC2, RNF8, RGN, FAM50A, BMP15, SLIT2, QKI, PICK1, ADAMTS2, GAL3ST1, TBPL1, CLOCK, SPAG6, PUM1, CEP57, UTP14C, SPATA2, KIAA0196, BCL2L10, BCL2L11, AKAP9, FSTL3, CRTAP, DEAF1, PRDX4, CCT6B, ADAM28, EDDM3A, PRSS21, CCNI, SOX30, HSF2BP, CIT, PTGDR2 |
2217 | GO:0006913 | 0.04 | 1.56 | 28.50 | 36 | 69 | nucleocytoplasmic transport | EGR2, EIF4E, EIF5A, GLE1, HHEX, AGFG1, HSPA9, CITED1, RPS28, SET, SRSF1, SRSF2, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, STYX, TSC1, U2AF1, ANP32A, SRSF9, DHX38, SMG7, ALYREF, DDX39A, NXF1, RGS14, AHCYL1, SRSF10, MALT1, RNPS1, NUPL2, AKAP13, XPOT, DDX19B |
2218 | GO:1901136 | 0.03 | 1.55 | 33.33 | 42 | 80 | carbohydrate derivative catabolic process | ADA, CD44, CDA, VCAN, CSPG4, DCN, DPYD, DUT, TYMP, GPC4, GPC5, GALC, GALNS, GPC3, GLB1, GM2A, GPC1, GPD1, HEXA, HEXB, IDS, IDUA, LUM, NUDT1, NTHL1, OMD, OGG1, OGN, OVGP1, SDC1, SDC2, SDC4, SGSH, SLC9A1, UNG, UPP1, MBD4, PGLYRP1, SDC3, GPC6, CSPG5, KERA |
2219 | GO:0045786 | 0.01 | 1.55 | 51.56 | 65 | 125 | negative regulation of cell cycle | ALOX15B, ATRX, BCL2, BCL2L1, BMP4, BUB1, BUB1B, CCNB1, CDC5L, CDC20, CDC27, CENPF, ATF2, CSNK2A1, CSNK2A2, DLG1, ETS1, FGFR3, GATA3, NR4A1, HPGD, PRMT2, MAD2L1, NUBP1, OVOL1, PRCC, PRKACB, PRKAR1A, PTPN3, RAD1, RPL24, RPS6KA2, SIPA1, SMARCA4, SOX11, TAF6, TOP2A, UBE2D1, XPC, ZBTB17, ZNF207, FZD3, SMC1A, TP63, TNKS, CDC23, HDAC3, CDC16, SMC3, ZW10, BUB3, AURKB, SLC9A3R1, MAD2L1BP, KNTC1, TOM1L1, CTDSP2, CTDSPL, ANAPC10, RBM14, MAD2L2, CREB3, STAG2, PTTG2, ZWINT |
2220 | GO:0030097 | 0.02 | 1.54 | 38.88 | 49 | 95 | hemopoiesis | ACTN1, ADAR, ADD1, ALAS2, ANGPT1, BMI1, BRCA2, CASP9, DNASE2, EEF2, EML1, EPB42, ERCC1, ETV2, FECH, FLI1, GFI1, SLC11A2, PIP4K2A, PRKX, PTPRZ1, ARID4A, REST, RHAG, RPS19, SRSF4, SLC8A3, SP1, SPTA1, SPTB, TAZ, TOP2A, PICALM, KCNAB2, CDK13, ARHGEF7, SGPL1, KRT75, KLF4, ZBTB24, PTBP3, ABI1, WASF2, KLF2, TACC3, KLF1, EBP, PRDX3, BVES |
2221 | GO:2001252 | 0.03 | 1.54 | 35.06 | 44 | 84 | positive regulation of chromosome organization | ATM, ATR, ATRX, BRCA1, CCNB1, CDK9, DNMT1, DNMT3B, ERCC1, GCG, KAT2A, HIST1H1B, IL1B, ISL1, JARID2, PRKD1, PRKCQ, MAPK3, RB1, SFPQ, SNAI2, SREBF1, TAL1, CCT3, VEGFA, CUL3, OGT, MAPKAPK5, TNKS, BECN1, EED, KAT2B, RPS6KA4, AURKB, RPS6KA5, DLGAP5, RNF40, RAD50, CCT7, CCT4, CCT2, CCT8, RUVBL2, ARID5A |
2222 | GO:0010639 | 0.01 | 1.54 | 47.04 | 59 | 113 | negative regulation of organelle organization | ATM, ATRX, AVP, BCL2L1, BMP4, BNIP3, BUB1, BUB1B, TSPO, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DNMT1, DNMT3B, DUSP1, ERCC1, ERCC4, FGFR3, GPX1, HGF, HMGA1, IGF1, INSIG1, JARID2, MAD2L1, OPA1, PHF2, PRKAR1A, RAD1, RPS6KA2, SET, SETMAR, SYT4, TAF7, TWIST1, UBE2D1, UCN, ZNF207, TNKS, CDC23, CDC16, ZW10, BUB3, TRIP12, ATG5, BAG4, FEZ2, KDM4A, RUBCN, TOM1L1, RAD50, ANAPC10, ACAA2, MAD2L2, ATG7, PTTG2, UBE2C |
2223 | GO:0072659 | 0.03 | 1.54 | 37.47 | 47 | 90 | protein localization to plasma membrane | AKT2, ANXA2, ATP1B3, BBS1, BBS2, BSG, CALCR, CAV3, CDH1, DPP6, EMP2, FCER1G, FLOT2, FYB, GAS6, GOLGA4, JUP, KRT18, LAMA5, RAB8A, P2RY1, PRKCZ, PTCH1, RAB13, RAC1, RAP2A, RDX, CLIP1, S100A10, SCP2, STXBP1, TNFRSF1A, TSC2, TULP1, TULP2, TULP3, BLZF1, RAB11A, LIN7A, MAP7, SLC9A3R1, BAG4, RAPGEF2, ARFRP1, RAMP2, VAMP5, RAB31 |
2224 | GO:0055085 | 0.00 | 1.54 | 324.06 | 400 | 780 | transmembrane transport | ABCA1, ABCA2, ABCB7, ABCA4, ACTN4, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADD1, ADD3, ALB, ABCD1, SLC25A4, ANXA5, ANXA6, APOA1, SHROOM2, AQP5, AQP6, AQP7, ARF1, ATP12A, ATP1B3, ATP2A1, ATP2B1, ATP2B2, ATP4A, ATP4B, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, ATP5O, ATP7B, AVP, AVPR2, AZGP1, BAX, BCL2, BCL2A1, HCN2, BMP4, CA2, CACNA1A, CACNA1B, CACNA1E, CACNA1F, CACNA1S, CACNA2D1, CACNB4, CACNG1, SLC25A20, SCARB1, CDH17, CFTR, CHRNB2, CHRNB4, CLCA1, CLCN2, CLCN3, CLCN5, CLCN6, CLCN7, CLCNKA, CLCNKB, CCR5, CNGA1, CNGA2, COX4I1, COX5B, COX6A1, COX6A2, COX6B1, COX7A1, COX7B, COX7C, COX8A, COX15, CP, CPT1B, CPT2, SLC25A10, CTNS, CTSS, CYBA, DIAPH1, DLG1, DNM2, DPP6, TSC22D3, EDN3, EDNRA, EIF2S1, EIF2S3, SLC29A1, STOM, F2R, FTL, G6PC, SLC37A4, GABRA4, GABRB2, GABRE, GABRG1, GABRR1, GABRR2, GAS6, GCG, GJA3, GJA5, GJB1, GJB2, GLRA1, GLRA2, GLRB, GNAS, GPM6A, XCR1, GRIA1, GRIA4, GRID1, GRID2, GRIK3, GRIN2A, HK2, HPN, HRC, HSPA4, HSPA8, HSP90AA1, HTR2C, HTR3A, IL13, INS, ITGAV, ITPR2, ITPR3, KCNA1, KCNA2, KCNA3, KCNA4, KCNA5, KCNA10, KCND2, KCND3, KCNJ2, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ12, KCNJ13, KCNJ14, KCNJ15, KCNJ16, KCNK2, KCNK3, KCNN1, KCNN4, KCNS1, KCNS2, KCNS3, MAL, SLC11A2, NUP88, NUP98, P2RX3, P2RX4, P2RX7, PDE4B, PDE4D, PDPK1, SLC26A4, PEX1, PEX6, PEX10, PEX12, PEX14, PIK3CG, FXYD3, PRKAB2, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKD1, RELN, PTAFR, PTPN3, PTPN6, PEX19, ABCD3, PEX5, RAF1, RANBP2, REST, RHAG, RHCE, RHD, ABCE1, RPS27A, RTN2, RYR1, RYR2, RYR3, S100A1, S100A6, SCN1A, SCN2B, SCN3A, SCN4B, SCN5A, SCN8A, SCN10A, SCNN1A, SCNN1B, SCNN1D, SCNN1G, CCL21, XCL1, SGK1, SLC1A6, SLC1A7, SLC2A2, SLC2A3, SLC2A4, SLC4A1, SLC5A2, SLC5A3, SLC5A5, SLC6A2, SLC6A4, SLC6A6, SLC6A7, SLC6A8, SLC6A11, SLC6A12, SLC6A13, SLC7A1, SLC7A4, SLC8A1, SLC8A3, SLC9A3, SLC9A5, SLC10A1, SLC10A2, SLC11A1, SLC12A1, SLC12A2, SLC12A3, SLC12A4, SLC13A1, SLC15A1, SLC15A2, SLC16A1, SLC34A1, SLC20A1, SLC20A2, SLC25A1, SLCO1A2, SNCA, SNTA1, STC1, ABCC8, SURF1, TRAPPC10, TRPC1, TRPC3, TRPC4, TRPC5, UBB, UCN, UQCRC1, UQCRFS1, UQCRH, VDAC2, TRPV1, YWHAH, SLC30A2, ZP3, BSND, TUSC3, NUP214, SLC25A16, CUL5, AAAS, SLC7A5, SLC14A2, SLC10A3, KCNAB2, KCNK5, SLC4A4, ABCC3, RIPK1, RAB11A, SLC5A6, EIF2S2, ATP6V0E1, HAP1, SLC13A2, RGN, ATP6V0D1, SLC16A6, SLC16A5, SLC16A4, SLC6A5, COX7A2L, SLC24A1, SLC16A7, KCNAB3, ATP6V1F, SLC22A6, SLC22A8, COX5A, NRXN1, SLC22A14, SLC22A13, PEX16, KCNK6, AKAP7, AKAP6, ATG5, SLC4A8, ATP6V1G1, ATP5J2, ABCG1, NUP155, NUP93, TOMM20, HEPH, C2CD5, SV2B, WDR1, SLC23A2, HCN4, ABCC5, ABCB6, ABCC9, SGK2, AKAP9, SLC25A13, SLC25A15, SLC35B1, KCNMB2, ABCC4, ABCA7, ABCA10, ABCA9, ABCA8, CACNG2, ATP8A1, RAPGEF3, TOMM40, SLC30A9, ATP5H, SLC25A17, SLC9A6, CHERP, SLC35A1, SLC34A2, SLCO1B1, ATP5L, CLDN16, NUP50, SLC26A1, SLC22A7, UQCR11, SLC38A3, SLC27A5, SLC27A4, SLC35D2, WWP1, WWP2, CACFD1, NUPL2, SLC7A9, IL1RAPL1, CORO1A, ABCB8, SCN11A, SLCO2B1 |
2225 | GO:0051259 | 0.00 | 1.54 | 86.30 | 108 | 208 | protein oligomerization | ACADL, ACADS, ACAT1, ACHE, ADSL, ALAD, ANXA5, ANXA6, ARG1, ASL, BAX, BID, BIK, CAMK2G, CAT, CAV2, CCK, ENTPD2, CDA, CLU, CLDN7, CRYAB, CRYZ, CTH, DECR1, DHPS, DNM1, DPAGT1, DPYSL3, ECT2, STOM, GJA5, GJB1, GLS, GLUL, GOLGA2, GPX3, HSD17B10, HMGCL, HMGCR, HPRT1, IGF1R, TNFRSF9, IMPDH2, INS, IRAK1, KCNA1, KCNA2, KCNA3, KCNA4, KCNA5, KCNA10, KCND2, KCND3, KCNJ2, KCNJ12, KCNS1, KCNS2, KCNS3, OAS1, OAT, OTC, OXA1L, P2RX3, P2RX4, P2RX7, PAM, PEX14, PLN, PEX5, RAD51, RPS19, RXRA, RXRG, RYR3, SHMT1, SHMT2, SLC6A4, SLC9A1, SLC34A1, SLC22A1, SOD2, SORL1, SPAST, SYT1, TNFAIP3, TP73, CLPP, TNFSF11, TP63, HRK, SLC22A6, GRHPR, EIF2AK3, CEP57, BCL2L11, TRIM28, AASS, TRIM22, OLFM1, OLFM4, USP16, MALT1, DHRS4, EHD1, TMED10, UPK1A, CPSF6 |
2226 | GO:0034654 | 0.00 | 1.54 | 906.25 | 1081 | 2180 | nucleobase-containing compound biosynthetic process | ABCA1, ABCA2, ACTN4, ACTL6A, ACTN1, ACVR1, ACVR1B, ACVR2A, ACVR2B, ADA, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADCYAP1R1, ADK, ADORA2A, ADRB2, ADSL, ADSS, AEBP1, AES, AGTR2, NR0B1, AHR, AK2, AK4, AKT2, ALK, ALX3, AMPD1, AMPD2, ANG, ANXA3, ANXA4, APBB1, XIAP, BIRC5, APLP1, APRT, AQP1, ARF4, RHOH, PHOX2A, ARNT, ARNTL, ASCL2, ATF3, ATF4, RERE, ATOH1, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, ATRX, AVP, AVPR2, BACH1, CCND1, BCL3, BCL7A, BCL9, PRDM1, BMI1, BMP1, BMP4, BMP6, BMP8B, BMPR1A, BRCA1, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTG1, BTK, C1QBP, CALCR, CALM3, CAMK4, CAMK2A, CAT, RUNX2, RUNX1T1, CBFB, CBL, CCNC, CCNE1, CCNH, CCNT1, CCNT2, CD3D, CD28, CD80, CD86, TNFSF8, CD36, CD38, CD40, CDA, CDC5L, CDC6, CDH1, CDK5, CDK8, CDK9, CDKN2A, CDX1, CDX2, CDX4, CEBPE, CEBPG, CENPB, CGA, CHD1, CHD2, CHD3, CHD4, CHUK, CLU, CMKLR1, COL1A1, COX4I1, COX5B, COX6A1, COX6B1, COX7B, COX7C, COX8A, ATF2, CREBL2, CRX, CRY1, CRY2, CRYM, CSNK2A1, CSNK2A2, CSTF3, CTH, CTNND1, CTNND2, CUX1, CYLD, DAB2, DGKQ, DCN, DDX1, DDX3X, DDX5, DHFR, DHODH, DLG1, DLX3, DLX5, DLX6, DNM2, DNMT1, DNMT3A, DNMT3B, ARID3A, ATN1, RCAN1, TSC22D3, DTX1, DTYMK, DUT, E2F2, E2F4, E2F5, E4F1, EBF1, TYMP, ECM1, EDA, S1PR1, LPAR1, EDNRA, EDNRB, EFNA1, CELSR2, EGR2, EGR3, EGR4, EIF4A2, ELAVL2, ELF1, ELF3, ELK1, ELK3, EMX1, EMX2, EN1, EP300, EPHA5, ERBB2, EREG, EYA4, ERCC3, ERCC6, ERG, ERN1, ESR1, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA1, EYA2, EYA3, EZH1, F2R, F2RL1, FAU, FBN1, EFEMP1, FGF1, FGF7, FGF8, FGF9, FGFR3, FOXD1, FLI1, FLII, FLNA, FRK, FSHR, NR5A1, GABPA, GALR1, GARS, GAS6, GATA3, GATA4, GATA6, GCG, KAT2A, NR6A1, GDF9, GDNF, GFI1, GHRH, GHRHR, GPC3, GLP1R, GLS, GMDS, GNAI3, GNAL, GNAS, SFN, GPS2, GPX2, ARHGAP35, GRM8, GSC2, GTF2F1, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, GUCA1A, GUCA1B, GUCA2A, GUCA2B, GUCY1B3, GUCY2C, GUCY2F, GUK1, GUCY2D, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, H2AFZ, H3F3B, HAS3, HCK, HCLS1, HDGF, HEXB, NRG1, HHEX, HIC1, HIF1A, HIP1, HIVEP2, HLF, HLX, HMGN1, HMGA1, NR4A1, HMX1, HMX2, FOXA2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD3, HOXD4, HOXD8, HOXD11, HPN, HPRT1, PRMT2, PRMT1, HES1, HSBP1, HSPA8, HTR2C, ICAM1, IFI16, SP110, IFNA2, IFNG, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL1B, IL10, FOXK2, ILK, IMPDH1, IMPDH2, ING2, INS, INSIG1, INSL3, IRAK1, ITGA6, IRAK2, IRF1, IRF2, IRF5, ISL1, ITGA3, JARID2, JUN, JUNB, JUND, JUP, KIT, KRAS, AFF3, LDHC, ABLIM1, LMO1, LTF, LUM, EPCAM, SMAD1, SMAD3, SMAD6, SMAD7, MAZ, MEIS1, MEOX2, CIITA, ATXN3, AFF1, FOXO4, CITED1, PPP1R12A, DRG1, RPL10A, TONSL, CNOT2, NRF1, NRL, YBX1, NTF3, NTRK1, NTRK2, NTRK3, DDR2, NUP88, NUP98, OAS1, OAS2, OGG1, SIX6, ORC1, ORC2, OTX1, OTX2, OVOL1, P2RY1, P2RY11, PA2G4, PCSK6, SERPINE1, PAM, PARK2, PAWR, PAX1, PAX2, PDCL, PAX9, PBX1, PCK1, CHMP1A, PDC, PDE8A, PDPK1, PEG3, PER1, PEX14, PF4, PFDN1, ATP8B1, PFN1, PGR, PHF2, PIM1, PRRX1, PPID, PPM1A, PPP1R8, PPP2R1A, PPP3R1, PPP5C, PRIM1, PRIM2, PRKAA1, PRKAB2, PRKAR1A, PRKCA, PRKCB, PRKCI, PRKD1, PRKCZ, MAPK8, EIF2AK2, PROX1, PRPS2, PRPSAP1, RELN, PSMA6, PSMC1, PSMC3, PSMC4, PSMC5, PTAFR, PTCH1, PTGER4, PTGIS, PTHLH, PTMA, PTPN14, PURA, RAF1, RAN, RANBP2, RARA, RARB, RB1, ARID4A, RBBP4, RBBP8, RBL1, RBL2, RCVRN, RELB, DPF2, REST, RFX2, RFX3, RFX4, RFXAP, RHEB, RNF2, RNF6, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS6KA1, RPS6KA3, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS28, RPS29, RREB1, RRM1, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A12, SAFB, SALL1, SATB1, ATXN7, XCL1, SET, SFPQ, SFRP4, SFRP5, SRSF1, SRSF2, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SFSWAP, SGK1, SHH, SHMT1, SIAH2, SIX1, SIX3, SLC9A1, SLC11A1, SNAI2, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCC2, SMARCD3, SMARCE1, SNAI1, SNAPC1, SNAPC2, SNAPC3, SNAPC4, SNCA, SNRPE, SNRPF, SOD2, SOX1, SOX2, SOX3, SOX4, SOX5, SOX9, SOX10, SOX11, SOX12, SP1, SP2, SP3, SP4, SP100, UAP1, SPIB, SREBF1, SRF, SRY, SSRP1, STAT2, STAT3, STAT4, STAT5B, SUPT4H1, SURF1, SUV39H1, SYK, T, TAF2, TAF4B, TAF5, TAF6, TAF7, TAF13, TAL1, TARBP1, TARBP2, TBL1X, TBP, HNF1A, ZNF354A, PRDX2, NR2F1, NR2F2, KLF10, NR2E1, TMF1, TMPO, TNFAIP3, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TRPS1, TSC1, TSC2, TSG101, TTF1, TULP3, TWIST1, TNFSF4, TNFRSF4, U2AF1, UBE2D1, UBE2D2, UBE2L3, UBE2V1, UBE3A, SUMO1, UBTF, UCN, UCP1, SCGB1A1, UGDH, UGP2, NR1H2, UPP1, USF1, USF2, VAV1, VDR, VEGFA, EZR, VIP, VIPR2, WFS1, WHSC1, WNT1, WNT2, WNT11, YWHAG, YWHAH, YWHAZ, ZFP36, ZFP37, ZFPL1, ZFX, ZIC1, ZIC2, ZNF3, ZNF711, ZNF7, ZNF8, CNBP, ZNF14, ZNF708, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF80, ZNF84, ZNF221, ZNF90, ZNF91, ZNF124, ZNF132, ZNF133, ZNF134, ZNF136, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, ZNF148, ZBTB17, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF180, ZNF189, ZNF207, ZNF214, ZNF223, ZNF224, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, ZP3, ZXDA, PRDM2, LRP8, CSDE1, PAX8, FZD5, BRPF1, MAFK, ARHGEF5, ZNF212, BRD3, NUP214, CSRP3, FOSL1, FGF23, AAAS, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, USP9Y, HIST1H4I, PICALM, CDC45, EOMES, FZD4, FZD6, FZD7, FZD8, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NR0B2, UTF1, CUL3, CUL2, FOXN1, TTF2, KLF11, OGT, ITGA8, IKBKG, IKBKAP, HAT1, CBX4, CAMK1, PIR, FCN3, BLZF1, KHSRP, STK16, TNFSF11, KLF7, CDK13, RFXANK, TP63, CHRD, DYNLL1, SRSF9, TRADD, EDF1, URI1, EED, RNGTT, RIPK1, RIPK2, SUCLG1, CREG1, TRIM24, SAP30, HESX1, CFLAR, HDAC3, TSC22D1, KAT2B, NR1I2, PER3, TAX1BP1, BUD31, CPNE1, BCL10, PHOX2B, FUBP3, KYNU, HIST1H3F, HIST1H2AG, USP13, RPS6KA4, TNFSF18, TAF1C, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, BTAF1, RPL14, AIP, PAPSS2, PAPSS1, USP2, PDLIM1, RQCD1, CBFA2T2, DYRK1B, CTDP1, COX7A2L, ARHGEF2, DDX21, BMP15, CCPG1, RPS6KA5, ITGB1BP1, ZNF235, TRIP11, HMGN3, TRIP4, GTF3C5, GTF3C4, GTF3C3, CNOT8, RPL23, CER1, COX5A, CIAO1, RECQL5, ZRANB2, HAND1, EIF2AK3, FHL5, HAND2, AKAP6, ATG5, ONECUT2, LITAF, TBPL1, ZNF254, CIR1, ATP5J2, GABBR2, NR1D1, CLOCK, SOX13, RBM39, CREB5, ABCG1, GUCA1C, NUP155, ZNF516, SAFB2, PHF14, KDM4A, VGLL4, NUP93, BZW1, ST18, ZNF646, VPRBP, USP34, SETD1A, ZNF536, HDAC4, ZFYVE16, BCLAF1, DHX38, SERTAD2, TSC22D2, RB1CC1, ZEB2, ZBTB24, ZNF518A, SETDB1, SUPT7L, RNF10, ZBTB5, NR1I3, NR1H4, NR1D2, DMTF1, CASP8AP2, NR2E3, SRA1, HDAC6, PQBP1, TSFM, PREB, ZNF263, YAF2, CEBPZ, TRIM28, SLC25A13, ZNF197, SORBS3, ALYREF, RNF41, CALCRL, OLIG2, TRIB1, ZNF443, COQ7, DENND4A, IRX5, RAMP2, RAMP3, FSTL3, STAG1, SAP18, APBB3, TNIP1, IKZF1, PCGF3, TRIM22, HMG20B, HMG20A, KLF2, CITED2, PIAS3, IFITM3, RAPGEF3, RBM14, PPIE, SLC30A9, TRIM38, ATP5H, CAP2, CAP1, CREB3, CARM1, ZNF211, DEAF1, ATG7, BATF, SIVA1, ERN2, USP16, ERLIN1, HEXIM1, RBCK1, ARID3B, IVNS1ABP, TRIM16, TXNIP, TAF6L, ATP5L, RGS14, DMRT2, KHDRBS1, KLF1, CTCF, RRAGA, TBR1, STAG2, SIX2, RAI1, PTTG2, PHTF1, NUP50, ZMYND11, SRSF10, ZBTB6, ZNF234, ZNF266, ZNF275, SRCAP, RUVBL2, SLC26A1, ARID5A, MALT1, BRD8, PAPOLA, RNPS1, PRDX3, ASCC3, SLC38A3, CCDC85B, ATF7, VAX1, RBPMS, PIM2, ADRM1, WWP1, WWP2, SOX30, HSF2BP, WDR5, NUPL2, PRDM7, ERLIN2, SOX21, PSIP1, STRAP, BAZ2A, ZNF277, SUPT16H, CHEK2, RPL35, SP140, SNF8, KLF12, KLF8, ECD, PHB2, ACOT7, CBX3 |
2227 | GO:0010638 | 0.01 | 1.54 | 55.87 | 70 | 135 | positive regulation of organelle organization | ACTL6A, ADRB2, BIRC5, BAD, BAX, BBS4, BCL2, BID, BIK, BNIP3, C1QBP, CASP8, CD28, CSF2, CSNK2A2, CTSK, DCN, EDN3, EREG, FGF8, SFN, GPR26, NRG1, HIF1A, HES1, IGF1, IGF1R, IGF2, IL1A, INS, ITGAX, KDR, LMAN1, CNOT2, OPA1, PARK2, PIP4K2A, PPP3R1, MAPK8, PSMB7, PSMD8, RAC2, RNASE2, RPL28, SDC1, SDCBP, AURKA, TSG101, U2AF1, UBE2L3, YWHAG, YWHAH, YWHAZ, ZBTB17, FZD5, BAP1, DYNLL1, HRK, TNFSF10, HAP1, ATG5, FAM20B, PAN2, PDCD6IP, BCL2L11, ARIH2, SIVA1, SEPT9, UBE2C, PHB2 |
2228 | GO:0000725 | 0.03 | 1.54 | 36.72 | 46 | 88 | recombinational repair | ATM, ATR, BARD1, BRCA1, BRCA2, ERCC1, ERCC4, FEN1, TONSL, PPP4C, RAD1, RAD51, RAD51B, RAD51D, RBBP8, RFC2, RFC3, RFC4, RFC5, RPA3, RPS27A, SFPQ, UBB, UBE2V2, SUMO1, WHSC1, WRN, XRCC2, SHFM1, HIST1H4I, CDC45, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HERC2, RNF8, EXO1, BRE, RAD50, RAD51AP1 |
2229 | GO:1902582 | 0.00 | 1.53 | 131.22 | 164 | 325 | single-organism intracellular transport | ACTN4, ADCYAP1R1, ADRB2, ATP1A2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, ATP7B, KIF1A, BAD, BAX, BCL2, BCL2L1, BICD1, BNIP3, VPS51, CACNG1, CALM3, CAMK2A, CASP8, CASQ2, CD4, CD63, CDC42, CDX2, CCR5, CNP, ATF2, SLC25A10, CYBA, DIAPH1, EDNRA, EIF4E, EMP2, EYA2, GLE1, XCR1, GSTM2, HHEX, HIF1A, HK2, AGFG1, HRC, HTR2C, ITGB1, ITPR1, ITPR2, ITPR3, KIF5A, KLC1, NTSR1, OPA1, P2RX3, P2RX4, PCM1, CHMP1A, PDE4D, PIK3C3, PLN, PRKACA, PRKCE, PRKCZ, MAPK8, PTPN6, RAB13, RAB5C, RDX, RPGR, CLIP1, RTN2, RYR1, RYR2, RYR3, CCL21, XCL1, SEL1L, SRSF1, SRSF2, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SLC8A1, SLC8A3, SLN, SOD1, SPG7, TRPC1, TRPC3, TRPM2, TSC1, TSG101, TST, UBB, UCP1, UFD1L, EZR, TRPV1, WRN, YWHAH, ALMS1, TUBA1A, STAM, CLTCL1, PICALM, UXT, EEA1, SSNA1, STX16, STX10, SRSF9, RAB11A, HAP1, SLC25A14, DCLK1, RAB11B, RAB9A, KIF3B, GSTO1, ATG5, ATP5J2, VPS26A, USP6NL, GPRASP1, IFT140, SNX17, DHX38, RGP1, SMG7, HDAC6, BCL2L11, HMGXB4, TOM1, ARL4C, SLC25A13, SLC25A15, ALYREF, DDX39A, STAM2, TRDN, TUBA1B, ACAA2, ATP5H, NXF1, SIVA1, ATP5L, SRSF10, RNPS1, EHD1, RAB32, IFT27, KIF3A, BVES, CORO1A, XPOT, DDX19B |
2230 | GO:0016192 | 0.00 | 1.53 | 133.85 | 167 | 328 | vesicle-mediated transport | A2M, ABCA1, ACHE, ACTB, ACTG1, ACTN1, ADORA1, ADORA2A, ADRB2, ADRBK1, ADRBK2, AP2B1, ALB, AMBP, ANXA3, ANXA11, APLP1, APOA1, ARF5, ARR3, ASGR1, ASGR2, BCL2L1, SERPING1, VPS51, CALCR, CALM3, CALU, CD3G, CD5, CD5L, CD6, CD9, CDC42, CEBPE, CETP, AP2M1, CLCN3, CLCN5, CLU, CCR1, ACKR2, COL1A1, COL3A1, CRP, DMBT1, EMP2, CTTN, FCGR2A, FCGRT, FCN1, FCN2, FLNA, FYN, GCGR, GDI2, GRB2, HBA1, HBA2, HGF, HP, HPX, HRG, HSP90AA1, HSP90AB1, IGF1, IGF2, IGF2R, INPPL1, ITGA4, ITPR1, ITPR2, ITPR3, KIT, KNG1, LAMP2, LIMK1, LLGL2, LRP3, LRPAP1, OLR1, CHMP1A, CDK16, ENPP1, ENPP2, ENPP3, PF4, PFN1, PIGR, PIK3C2A, PIK3C3, PIK3CG, PI4KB, SRGN, PRKCE, PTPRN2, RARA, S100A10, S100A13, SELP, SHH, SLC9A3, SIGLEC1, SOD1, SPARC, SYP, CNTN2, ICAM5, TMPRSS2, TNFAIP2, TUBA4A, TYRO3, UBE3A, VAV1, VCL, VEGFB, VEGFC, LAT2, ZFPL1, LRP8, CUBN, CLTCL1, SRPX, FCN3, BECN1, CPNE1, KALRN, PSTPIP1, RABEP1, PDLIM7, CYTH2, TRIP10, CD163, CPNE6, ZFYVE9, VPS26A, RIN1, USP6NL, SCRN1, RGP1, ELMO1, WDR1, ABI1, TOM1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, KIF20A, ACTR1A, ARL4C, WASF2, CALCRL, PRG4, ABCC4, RAMP2, RAMP3, SPON2, BAIAP2, CLEC10A, CAP1, ARPC1A, ARFGEF1, KDELR3, TUSC2 |
2231 | GO:0032271 | 0.05 | 1.53 | 30.42 | 38 | 73 | regulation of protein polymerization | APC, ARF1, ARF6, ARL2, CAV3, DLG1, CTTN, GRB2, HCK, HCLS1, ICAM1, PRKCE, RAC1, RGS2, RPS3, CLIP1, CCL21, CCL24, WASF1, LATS1, PICK1, BAG4, GMFG, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, ABI2, TUBGCP3, CDC42EP2, BAIAP2, ARPC1A, CDC42EP3, TPPP, CDC42EP1, CORO1A |
2232 | GO:0080090 | 0.00 | 1.53 | 1189.05 | 1389 | 2898 | regulation of primary metabolic process | A2M, AARS, ABAT, ABCA1, ABCA2, ABL2, ACO1, ACTN4, ACTL6A, ACTN1, ACVR1, ACVR1B, ACVR2A, ACVR2B, ACVRL1, ADAR, ADARB1, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADORA2A, ADRA2C, AEBP1, AES, AGTR2, NR0B1, AHR, AHSG, ALK, ALOX12, ALX3, AMBP, ANG, ANGPT1, ANPEP, ANXA2, ANXA3, ANXA4, APBB1, APCS, BIRC3, XIAP, BIRC5, APLP1, APLP2, AQP1, AREG, ARF4, RHOH, PHOX2A, ARNTL, ARR3, ASCL2, SERPINC1, ATF3, ATF4, ATM, RERE, ATOH1, ATP6AP1, ATR, ATRX, AVPR2, BACH1, BARD1, BAX, CCND1, BCL2, BCL3, BCL7A, BCL9, BDKRB2, BID, PRDM1, BMI1, BMP1, BMP4, BMP8B, BMPR1A, BMPR2, BOK, BRCA2, BRDT, ZFP36L2, BST2, KLF9, KLF5, BTF3, BTG1, BTK, BUB1, BUB1B, C1QBP, SERPING1, C5, C8B, CALCR, CALM3, CAMK4, CAMK2A, CAMK2G, CASP8, CASP9, CAT, CAV2, CAV3, RUNX2, RUNX1T1, CBFB, CBL, CBLB, SERPINH1, CCK, CCNB1, CCND3, CCNE1, CCNH, CCNT1, CCNT2, CD3D, CD4, CD14, CD28, CD80, CD86, TNFRSF8, TNFSF8, CD36, CD38, CD40, CD44, CD59, CD74, CDA, CDC5L, CDC6, CDC20, CDC25C, CDC27, CDH1, CDK4, CDK5, CDK8, CDK9, CDKN1A, CDKN2A, CDKN2C, CDKN2D, CDX1, CDX2, CDX4, CEBPE, CEBPG, CENPB, CENPE, CENPF, CGA, CHAD, CHD1, CHD2, CHD3, CHD4, CHI3L1, CHRNB2, CHUK, CIRBP, CISH, CKS1B, CLU, CLK3, CCR1, CMKLR1, CNTF, COL1A1, COL4A3, COL6A3, CPA3, CR1, ATF2, CRX, CRY1, CRY2, CRYAB, CRYBA1, CRYM, CSF2, CSF2RB, CSNK1D, CSNK2A1, CSNK2A2, CSPG4, CST1, CST6, CTF1, CTGF, CTH, CTNND1, CTNND2, CTSG, CTSZ, CUX1, CYLD, DAB2, CD55, DGKQ, DAZ1, DCN, ACE, GADD45A, DDX1, DDX3X, DDX5, DDX6, DFFA, DHCR24, DHFR, DIO2, DLG1, DLG2, DLG3, DLX3, DLX5, DLX6, DNM2, DNMT1, DNMT3A, DNMT3B, DPEP1, ARID3A, ATN1, RCAN1, TSC22D3, HBEGF, DTX1, DUSP1, DUSP4, DUSP5, DUSP7, DUSP9, DYRK1A, E2F2, E2F4, E2F5, E4F1, EBF1, GPR183, ECM1, ECT2, EDA, S1PR1, LPAR1, EDN3, EDNRA, EDNRB, EEF2, EFNA1, EFNA5, CELSR2, EGR2, EGR3, EGR4, EIF2S1, EIF2B1, EPHA2, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4EBP1, EIF4EBP2, EIF4G1, EIF4G2, EIF5, EIF5A, SERPINB1, ELAVL2, ELAVL1, ELF1, ELF3, ELK1, ELK3, EMP2, EMX1, EMX2, EN1, ENPEP, ENSA, EP300, EPHA1, EPHA4, EPHA5, EPHA7, EPHB1, EPRS, ERBB2, ERCC1, EREG, EYA4, ERCC3, ERCC4, ERCC6, ERG, ERN1, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA1, EYA2, EYA3, EZH1, F2R, F2RL1, F3, F12, ACSL1, FBLN1, FBN1, EFEMP1, FCER1A, FECH, FGA, FGF3, FGF6, FGF7, FGF8, FGF9, FGG, FOXD1, FLI1, FLII, FLNA, FLOT2, FLT3LG, FLT4, AFF2, FNTA, FPR1, FRK, FSHR, FYN, IFI6, GABPA, GALR1, GAPDH, GAS1, GAS6, GATA4, GATA6, NR6A1, GDF9, GDNF, GFAP, GHRH, GHRHR, GPC3, GLP1R, GNAI3, GNAL, GNAQ, GNAS, SFN, GP1BA, GPS2, GPX1, GRB2, GRB7, RAPGEF1, GRIN2A, ARHGAP35, GRM1, GRM8, GSC2, GTF2F1, GTF2I, GTF3A, BRF1, GUCA1A, GUCA1B, GUCA2A, GUCA2B, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, H2AFZ, H3F3B, HAS3, SERPIND1, HCK, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIP1, UBE2K, HIVEP2, HLF, HLX, HMGN1, HMGCR, HMGA1, NR4A1, HMX1, HMX2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD3, HOXD4, HOXD8, HOXD11, HPRT1, HPX, HRC, HRG, PRMT2, PRMT1, HES1, HSBP1, DNAJB2, HSPA8, HSPB1, HSP90AA1, HSP90AB1, ICAM1, IDE, IFI16, SP110, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGF1R, RBPJ, IHH, IL1A, IL2RA, IL2RB, IL2RG, IL10, IL13, IL18, FOXK2, ILK, ING2, INHA, INSL3, EIF3E, IRAK1, ITGA6, IRAK2, IREB2, IRF1, IRF2, IRF5, ISL1, ITGA1, ITGA2, ITGA3, ITGA5, ITGAV, ITGB1, ITIH1, ITIH2, ITIH3, ITIH4, ITPKB, JARID2, JUN, JUNB, JUND, JUP, KCNK2, KDR, KISS1, KLKB1, KNG1, KPNA1, KRAS, AFF3, ABLIM1, LIMK1, LMO1, LTF, LUM, EPCAM, CAPRIN1, MAD2L1, SMAD1, SMAD3, SMAD6, SMAD7, MARK3, MAZ, CD46, MEIS1, MAP3K5, MEN1, MEOX2, KITLG, MGMT, CIITA, ATXN3, MAP3K11, AFF1, FOXO4, CITED1, PPP1R12A, TONSL, CNOT2, SLC11A2, NRAS, NRF1, NRL, YBX1, NTF3, NTRK1, NTRK2, NTRK3, DDR2, NVL, OAS1, OAS3, OGG1, TNFRSF11B, OPHN1, SIX6, ORC1, ORC2, OTX1, OTX2, OVOL1, P2RY11, PA2G4, PEBP1, PCSK6, SERPINE1, PAM, PAWR, PAX1, PAX2, PDCL, PAX9, PBX1, SERPINA5, PCK1, PCOLCE, CHMP1A, PCP4, PDE4D, PDE6G, PDE6H, PDE8A, PDE1B, ENPP2, PDPK1, SERPINF1, PEG3, PER1, PEX14, PF4, CFP, PFDN1, ATP8B1, PFN1, PFN2, PGR, PHB, PHF2, PI3, SERPINB6, SERPINB8, SERPINB9, SERPINB10, SERPINI1, SERPINB13, PIK3CB, PIM1, PRRX1, PPID, PPM1A, PPP1R1A, PPP1R2, PPP1R7, PPP1R8, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PPP4C, PPP3R1, PPP5C, PRG2, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCB, PRKCG, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK3, MAPK8, EIF2AK2, DNAJC3, PROS1, RELN, PTBP1, PTCH1, PTGIS, PTHLH, PTPN1, PTPN3, PTPN6, PTPN14, PTPRA, PTPRJ, PTPRR, PTPRZ1, PURA, PZP, RAB1A, RAC2, RAD51, RAF1, RAG1, RAN, RAP1A, RAP2A, RAP2B, RARA, RARB, RASA2, ARID4A, RBBP4, RBBP6, RBBP8, RBM3, RBM4, RCVRN, RDX, RELB, DPF2, RFC1, RFX2, RFX3, RFX4, RFXAP, RGS2, RNF2, RNF6, RPL6, RPL38, RPS3, RPS4X, RPS6KA1, RPS6KA2, RPS6KA3, RPS6KB2, RPS26, RPS27A, RRAS, RREB1, RRM2, RXRA, RXRG, RYK, RYR2, S100A1, S100A8, S100A9, S100A11, S100A12, SAFB, SALL1, SATB1, ATXN7, SERPINB3, SERPINB4, CCL20, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SDCBP, SEMG1, SET, SETMAR, SFPQ, SFRP4, SFRP5, SRSF2, SRSF4, SRSF6, SRSF7, SFSWAP, TRA2B, SFTPD, SGK1, SGTA, SHC1, SHH, SIAH2, STIL, SIX1, SIX3, SKP1, SKP2, SLAMF1, SLC9A1, SLC11A1, SLPI, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCC2, SMARCD3, SMARCE1, SMPD1, SUMO3, SNAPC1, SNAPC2, SNAPC3, SNAPC4, SNRNP70, SNTA1, SOD2, SON, SORL1, SOS1, SOX1, SOX2, SOX3, SOX4, SOX5, SOX9, SOX10, SOX11, SOX12, SP1, SP2, SP3, SP4, SP100, SPIB, SPINK1, SPINT1, SPN, SPTA1, SPTB, SRF, SRP9, SRPK2, SRY, SSRP1, STAT2, STAT4, AURKA, STK10, STYX, SUPT4H1, SUPV3L1, SUV39H1, XCL2, SYK, T, TACR3, TAF2, TAF4B, TAF5, TAF6, TAF7, TAF13, TAL1, TARBP1, TARBP2, CNTN2, SERPINA7, TBL1X, TBP, HNF1A, ZNF354A, NR2F1, NR2F2, KLF10, NR2E1, TMF1, TMPO, CLEC3B, TNFAIP3, TNFRSF1B, TNNI2, TOP2A, TP73, TPD52L1, NR2C1, NR2C2, TRAF1, TRAF2, CCT3, TRIP6, TRPS1, TSC1, TSC2, TSG101, TTF1, TULP3, TNFSF4, TNFRSF4, TYMS, UBB, UBE2D1, UBE2D2, UBE2L3, UBE2V1, UBE2V2, UBE3A, SUMO1, UBTF, UCN, UCP1, SCGB1A1, UNG, USP4, USF1, USF2, UVRAG, VAV1, VEGFA, VEGFB, VEGFC, VIL1, EZR, VIP, VIPR2, VTN, EIF4H, WFS1, WHSC1, WNT1, WNT2, WNT11, YWHAG, YWHAH, ZFP36, ZFP37, ZFPL1, ZFX, ZIC1, ZIC2, ZNF3, ZNF711, ZNF7, ZNF8, CNBP, ZNF14, ZNF708, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF80, ZNF84, ZNF221, ZNF90, ZNF91, ZNF124, ZNF132, ZNF133, ZNF134, ZNF136, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, TRIM25, ZNF148, ZBTB17, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF180, ZNF189, ZNF207, ZNF214, ZNF223, ZNF224, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, ZXDA, PRDM2, LRP8, CSDE1, FZD5, BRPF1, RAB7A, AIMP2, MAFK, ARHGEF5, ZNF212, BRD3, CSRP3, FOSL1, FGF23, USP5, CDK2AP1, IFT88, ANP32A, AKAP1, ZNF239, SYMPK, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, SMC1A, USP9Y, HIST1H4I, PICALM, CDC45, EOMES, FZD4, FZD6, FZD7, FZD8, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, BCAR3, LTBP4, ZNF282, NR0B2, UTF1, RECK, CUL4B, CUL4A, CUL3, CUL2, CUL1, FOXN1, TTF2, KLF11, SEMA7A, ITGA8, IKBKG, IKBKAP, HAT1, CBX4, CAMK1, PIR, FCN3, BLZF1, MAPKAPK5, CDC14B, MADD, KHSRP, PRKRA, STK16, TNFSF11, KLF7, CDK13, RFXANK, TP63, CHRD, PDE5A, DYNLL1, TNKS, EIF3A, EIF3B, EIF3D, EIF3F, EIF3G, EIF3J, PEA15, SRSF9, CDC23, SERPINB7, TRADD, URI1, EED, RIPK1, CRADD, TNFSF14, TNFSF13, TNFSF12, TNFSF10, ADAM9, RIPK2, TNFRSF6B, TNFRSF18, TNFRSF10B, TNFRSF10A, CREG1, TRIM24, SAP30, HESX1, IQGAP1, CFLAR, HDAC3, TSC22D1, NR1I2, PER3, CDC123, CDC16, TAX1BP1, EIF2B4, EIF2B3, EIF2B2, EIF2B5, BUD31, CPNE1, BCL10, PHOX2B, FUBP3, CDK5R2, HIST1H3F, HIST1H2AG, USP13, RPS6KA4, TNFSF18, HAP1, TAF1C, TAF1B, TAF1A, SOCS3, RNF8, BAZ1B, UBA3, BTAF1, AIP, DIRAS3, USP14, USP2, LATS1, PDLIM1, RQCD1, SMC3, AIFM1, CCNE2, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, ZW10, BUB3, BMP15, AURKB, VAPB, CCPG1, CRLF1, RPS6KA5, ITGB1BP1, GPR55, S1PR2, SOCS6, ZNF235, TRIP12, TRIP11, HMGN3, TRIP4, CNOT8, TAOK2, CER1, SLIT2, SLC9A3R1, LIPG, CIAO1, RECQL5, ZRANB2, HAND1, QKI, FHL5, HAND2, IL27RA, AKAP6, ATG5, ONECUT2, LITAF, GDF15, TBPL1, BAG5, BAG4, ZNF254, GMFG, CIR1, SEC22B, GTPBP1, GABBR2, CLOCK, BRE, SOX13, RBM39, CREB5, WTAP, CARTPT, TRAF4, GUCA1C, ZNF516, SAFB2, EIF5B, PHF14, KDM4A, VGLL4, BZW1, RAPGEF2, PUM1, DHX34, ST18, ZNF646, VPRBP, USP34, SETD1A, ZNF536, SLK, ZFYVE16, RASSF2, BCLAF1, DLGAP5, SERTAD2, IST1, RNF40, CTIF, KIAA0141, SFI1, TSC22D2, RB1CC1, RGP1, ZEB2, ZBTB24, ZNF518A, PPP1R26, SETDB1, NUAK1, SUPT7L, RNF10, ZBTB5, OXSR1, TNFSF15, NR1I3, RBX1, DMTF1, PTBP3, KCNE2, CASP8AP2, NR2E3, ACOT8, ABI1, SRA1, HDAC6, PDCD6, BCL2L10, BCL2L11, PARP3, TOM1L1, RANBP9, PQBP1, TSFM, CTDSP2, RAD50, PREB, FEM1B, ZNF263, FRY, TRAP1, YAF2, AKAP9, EBI3, CEBPZ, TRIM28, RASA4, ATP6AP2, FARP1, ZNF197, SORBS3, TNK2, ALYREF, RNF41, CALCRL, EIF1, OLIG2, PRG4, CTDSPL, TRIB1, ZNF443, COQ7, DENND4A, SF3B4, IRX5, RAMP2, RAMP3, FSTL3, STAG1, SAP18, EIF1B, APC2, APBB3, TNIP1, IKZF1, PCGF3, TRIM22, ABCA7, HMG20B, HMG20A, KLF2, CITED2, ANAPC10, PRG3, PIAS3, IFITM3, RAPGEF3, CD2BP2, ARIH2, RBM14, OLFM1, ZER1, PPIE, MAD2L2, SLC30A9, TRIM38, EIF3M, CAP2, CAP1, CREB3, CRTAP, STK25, CARM1, ZNF211, DEAF1, ATG7, BATF, ARL6IP5, SIVA1, CCT7, CCT4, CCT2, ERN2, USP16, HEXIM1, RBCK1, ARID3B, TRIM16, TXNIP, TAF6L, RAD51AP1, RGS14, IGF2BP3, SPINT2, DMRT2, KHDRBS1, KLF1, CTCF, CCT8, CERS1, TBR1, NRG3, STAG2, SIX2, RAI1, PTTG2, PHTF1, GIPC1, AHCYL1, ZMYND11, SRSF10, ZBTB6, ZNF234, ZNF266, SEC24A, SPINT3, FRS3, ZNF275, SRCAP, RUVBL2, ARID5A, USP19, MALT1, CPSF4, JTB, BRD8, PAPOLA, COPS8, RNPS1, PRDX3, OS9, ERP29, TMED10, ASCC3, SLC38A3, SPINK5, CCDC85B, IL24, ATF7, VAX1, RBPMS, PIM2, ADRM1, WWP1, WWP2, SOX30, UBE2C, WDR5, PRDM7, CDC37, GLMN, SOX21, PSIP1, STRAP, BAZ2A, ZNF277, MAP4K5, RASSF1, SUPT16H, CHEK2, FZD10, AKAP13, SP140, SNF8, KLF12, KLF8, STK38, PHB2, CBX3 |
2233 | GO:0010977 | 0.05 | 1.52 | 29.63 | 37 | 71 | negative regulation of neuron projection development | ADCY6, ARF6, ARHGAP4, CDK5, DCC, DPYSL3, LPAR1, EFNA1, EPHA4, EPHA7, EFEMP1, GAK, GDI1, GFAP, GFI1, PTPRZ1, RNF6, SEMA3F, TNR, VIM, YWHAH, SEMA3B, CBFA2T2, SLIT2, BAG5, AATK, RAPGEF2, SEMA3E, KIAA0319, SEMA3A, CARM1, SEMA6C, SEMA6B, SEMA4F, SEMA4B, STMN2, CIT |
2234 | GO:0065008 | 0.00 | 1.52 | 156.55 | 197 | 420 | regulation of biological quality | AARS, ADGRB2, BCL3, HCN2, BID, BNIP3, BNIP3L, ZFP36L2, CACNA1S, CASP8, CDC20, CDKN2A, CHRNB2, CIRBP, CNGA1, CNGA2, CNP, CNR2, ATF2, CREBL2, CTNNA2, CTNND2, CX3CR1, DBI, DBN1, DHX9, COCH, DPP6, DSC3, EGR2, EIF4EBP2, EIF4G1, ELAVL1, EPHB1, EPHB3, ETV5, EYA2, FBN1, FGD1, FLOT2, B4GALNT1, GAPDH, GAS2, KAT2A, GLRA1, GLRB, GM2A, GPR26, GRIA1, GRID2, GRIK3, GRIN2A, ARHGAP35, HIST1H1B, UBE2K, IL10, ITGA7, KCNA2, KCND2, KCND3, KCNK2, TNPO1, LTBP1, RAB8A, TONSL, YBX1, NTRK1, PAWR, PEX6, ATP8B1, PHB, EXOSC9, PPP3R1, MAPK8, RELN, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PYY, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTN, PTPRJ, PEX19, PYCR1, RARA, RPS27A, S100A13, S100B, SCN1A, SCN3A, SCN8A, SEL1L, SET, SIAH1, SIX1, SLIT1, SORL1, SPAG4, AURKA, SYP, NR2E1, TNFRSF1B, TNNC1, TNNT2, TPBG, TRIP6, SUMO1, SCGB1A1, USP4, UVRAG, YWHAG, YWHAH, ZFP36, ZNF207, ANP32A, NRIP1, CNTNAP1, CAMK1, KHSRP, KCNK5, DYNLL1, TNFSF13, HDAC3, USP13, USP2, S1PR2, TAOK2, CER1, CRIPT, QKI, AKAP7, PSMF1, BAG3, RIN1, RAPGEF2, PUM1, FRMPD4, PSMD6, SUPT7L, USP3, KCNE3, HDAC6, ATP9A, TSPAN1, PSME3, ABCA7, CACNG2, ATP8A1, PIAS3, TMEM147, IFI30, ACAA2, TACC3, CREB3, CRTAP, ARL6IP5, PDLIM5, RGS14, GIPC1, USP19, PRDX3, KDELR1, OS9, FERMT2, KDELR3, PIM2, WWP2, UBE2C, CACFD1, CDC37, RASSF1, CHEK2, SCN11A, PHB2, EXOSC8 |
2235 | GO:0007259 | 0.05 | 1.52 | 31.27 | 39 | 75 | JAK-STAT cascade | CD40, CHAD, CNTF, CSF2, CTF1, DCN, F2R, FGFR3, FLT3, FYN, GP1BA, HCLS1, HPX, HES1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IL10, IL13, IL18, ISL1, KIT, PPP2R1A, PTGER4, STAT2, STAT4, TNFRSF1A, TNFRSF18, TNFSF18, CRLF1, SOCS6, SH2B2, STAMBP, IL24 |
2236 | GO:0006810 | 0.00 | 1.52 | 167.29 | 209 | 440 | transport | ACO1, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADD1, ADD3, PARP4, ANXA6, APRT, SHROOM2, ASNA1, ATP12A, ATP2A1, ATP2B1, ATP4B, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5O, ATP7B, KIF1A, CCND1, BCL2A1, BNIP3, CDO1, CDX2, CHUK, CLCA1, CLNS1A, CCR5, CNGA1, CNGA2, CNP, COX4I1, COX5B, COX6A1, COX6A2, COX6B1, COX7A1, COX7B, COX7C, COX8A, COX15, CP, ATF2, CSF2, CTGF, CXADR, CYP27B1, DBI, DHODH, TSC22D3, CELSR2, EIF2S1, EIF2S3, EYA2, FABP2, FABP7, FGF7, GABRA4, GABRB2, GABRE, GABRG1, GABRR1, GABRR2, GAD1, GAD2, GJA3, GJA4, GJB2, GLRA2, GLRB, GPM6A, XCR1, GRIA4, GRID1, GRID2, GRIK3, GRIN2A, GUCA1B, GUCA2B, HAS2, HBM, HBD, HBG1, HBG2, HBQ1, HPN, HRH2, HTR3A, IREB2, KCNK2, KCNK3, KCNN1, KIF5A, KLC1, LTF, MAL, MAP6, CITED1, OPA1, ORM2, P2RY4, P2RY6, PCSK6, ABCB1, RBP1, RBP2, RLBP1, ABCE1, RYR1, RYR3, S100A6, SCNN1A, SCNN1D, SCNN1G, SET, SLC5A5, SLC9A5, SLC12A1, SLC12A3, SLC12A4, SLC13A1, SLC20A1, SLC20A2, SPG7, STAT5B, SURF1, SYPL1, DYNLT3, TP73, TPD52, TPT1, CCT3, TRPC5, UBB, UCP1, UQCRC1, UQCRFS1, UQCRH, USF2, VDR, WRN, SLC30A2, LAPTM5, BSND, ALMS1, TUBA1A, TUSC3, SLC25A16, CUL5, ANP32A, SYN3, UBL4A, UXT, NR1I2, EIF2S2, SLC25A14, DGKI, COX7A2L, SLC24A1, DCLK1, TRIP4, NRXN3, KIF3B, COX5A, NRXN2, MPDU1, ATP5J2, GPRASP1, HEPH, SV2B, HMGXB4, ABCC9, ABCF2, COX17, G3BP1, KCNMB2, TUBA1B, SLC30A9, ATP5H, SLC9A6, FBLN5, AGR2, SLC34A2, CCT7, CCT4, CCT2, ATP5L, RGS14, CSPG5, EBP, CCT8, MALT1, UQCR11, WWP1, CACFD1, KIF3A, ABCB8, AKAP13, TMC6 |
2237 | GO:0046942 | 0.03 | 1.52 | 37.72 | 47 | 91 | carboxylic acid transport | ADORA1, AGXT, ARG1, ATP1A2, AVP, CCK, SLC25A10, CTNS, FOLR3, GLS, KCNJ10, SEPT2, NTRK2, SLC26A4, RAB3A, SLC1A6, SLC1A7, SLC6A6, SLC6A7, SLC6A8, SLC7A1, SLC7A4, SLC11A1, SLC25A1, SNAP25, SNCA, STXBP1, SYT1, TRPV1, XK, SLC7A5, SLC13A2, SLC6A5, SLC22A6, SLC23A2, SLC25A13, SLC25A15, UNC13B, ARL6IP5, GIPC1, CPLX1, SLC26A1, SERINC3, SLC38A3, SLC7A9, PRAF2, HRH3 |
2238 | GO:0006796 | 0.00 | 1.51 | 209.31 | 260 | 536 | phosphate-containing compound metabolic process | ACHE, ACP1, ACP2, ACP5, ACYP1, ACYP2, ADA, ADAM10, ADRBK1, ADRBK2, ALPI, ALPP, ALPPL2, AMHR2, BIRC5, APOA4, ATR, AXL, BLK, BMX, BTK, BUB1, BUB1B, CAMK4, CAT, ENTPD2, CDK3, CDK6, CDK8, CETP, CHKA, CHKB, CHUK, CKM, CLK3, CCR5, CNP, CPS1, ATF2, CRY1, CRYAB, CSNK1G2, CSNK1G3, CSNK2A1, CSNK2A2, CTSG, DGKA, DGKB, DGKQ, DBI, DCX, DHFR, DTYMK, DUT, DYRK1A, TYMP, EIF2S1, ELK1, EPHA3, EPHA5, EPHB2, EPHB3, EYA4, ERCC3, ERG, EYA1, EYA2, EYA3, EFEMP1, FDFT1, FDPS, FRK, FYB, G6PC, GAK, GALK1, GALK2, GARS, GATA6, GK, GK2, GPD2, GRK6, GPX1, HADHA, HCK, HEXB, IL12RB2, INSRR, ITGAV, KHK, LCAT, LIMK1, LIMK2, LIPE, SMAD1, MDH1, MDH2, CIITA, NUDT1, NRTN, NTHL1, OAS1, OAS2, OGG1, CDK16, PCYT1A, PDK4, ENPP3, PHKA2, PHKG1, PIGC, PIK3C2A, PIK3C2B, PIK3C3, PI4KA, PI4KB, PIP4K2A, PPM1A, PPM1B, PPM1G, PPP1CA, PPP1R3C, PPP2CB, PPP4C, PPP3R1, PPP6C, PRKCB, PRKCG, PRKCI, PRKCQ, PRKG1, MAPK8, PRKX, PSKH1, PSPH, PTGIS, PTK7, PTPN3, PTPN4, PTPN7, PTPN12, PTPN13, PTPN14, PTPRB, PTPRD, PTPRE, PTPRH, PTPRM, PTPRN, PTPRN2, ALDH18A1, RARA, RBM4, RPS6KA1, RPS6KA2, RPS6KA3, RPS6KB2, RRM1, RRM2, SBF1, SGK1, SHMT1, SKP1, SLC20A1, SMPD2, SORD, SRMS, SRPK2, STAT4, AURKA, CDKL5, TOP1, TPTE, NR2C2, TRIO, TYK2, TYMS, TYRO3, UGP2, UNG, VRK1, WEE1, PTP4A1, SCG2, EPM2A, PDHX, PIP5K1B, DYRK2, CUL1, CDC42BPA, PPM1D, KCNAB2, DGKE, CDC14B, CDC14A, PDXK, PRKRA, STK16, CDK13, TNKS, DGAT1, TNK1, RNGTT, RIOK3, DYRK4, SUCLG1, TRIM24, CDKL1, CPNE1, MBD4, KYNU, KALRN, BAZ1B, DYRK1B, CTDP1, DGKI, DCLK1, AURKB, STK17B, STK17A, CPNE6, LIPG, GGPS1, ARHGEF6, PICK1, PIGL, TBPL1, TP53I3, CDC42BPB, PRDX6, AATK, VPRBP, DLGAP5, PTDSS1, DNAJC6, FIG4, FAM20B, XYLB, GNE, PIGK, SH2D3C, SH2D3A, PTPRU, COL4A3BP, SGK2, ABI2, TRIM28, SPEG, BCKDK, AKR1A1, CEPT1, PRDX4, AGPAT2, ERN2, SMPDL3A, SERINC3, PIM2, PTPN21, CIT |
2239 | GO:0033044 | 0.04 | 1.51 | 34.56 | 43 | 83 | regulation of chromosome organization | APC, BUB1, BUB1B, CDC6, CDC20, CDC27, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, ERCC4, GATA3, GFI1, HMGA1, MAD2L1, PHF2, MAPK8, SET, SETMAR, SNCA, TAF7, TRPS1, TWIST1, UBE2D1, UCN, ZNF207, CDC45, CDC23, CDC16, ZW10, BUB3, TRIP12, ATG5, KDM4A, ANAPC10, MAD2L2, ATG7, CTCF, PTTG2, UBE2C, CIT, WDHD1 |
2240 | GO:1903308 | 0.04 | 1.51 | 33.80 | 42 | 81 | regulation of chromatin modification | ATM, BRCA1, CCNB1, CDK9, DNMT1, DNMT3B, GATA3, GCG, KAT2A, GFI1, HIST1H1B, HMGA1, IL1B, ISL1, JARID2, PHF2, PRKD1, MAPK3, MAPK8, SET, SNAI2, SNCA, SREBF1, TAF7, TRPS1, TWIST1, UCN, VEGFA, CDC45, OGT, EED, KAT2B, RPS6KA4, RPS6KA5, TRIP12, ATG5, KDM4A, RNF40, ATG7, CTCF, RUVBL2, ARID5A |
2241 | GO:0007219 | 0.02 | 1.51 | 47.58 | 59 | 114 | Notch signaling pathway | ADAM10, AGXT, ANXA4, ATOH1, CCND1, CCNC, CDH6, CDK6, CDK8, DTX1, S1PR3, EP300, ETV2, EYA1, FCER2, B4GALT1, GMDS, GOT1, HHEX, HIF1A, FOXA2, ONECUT1, HOXD3, HES1, RBPJ, IL2RA, KCNA5, KIT, KRT19, LLGL2, CD46, PGAM2, PLN, RFNG, RPS19, RPS27A, SEL1L, SKP1, SNAI2, SNAI1, SOX2, SOX9, STAT3, TBL1X, UBB, WNT1, IFT88, NR0B2, CUL1, SORBS2, TP63, NUMB, DLK1, HDAC3, KAT2B, ITGB1BP1, NR1H4, RBX1, RCAN2 |
2242 | GO:0044089 | 0.02 | 1.50 | 43.49 | 54 | 105 | positive regulation of cellular component biogenesis | APOA1, ATM, ATR, ADGRB2, BBS4, CLU, COL16A1, CTGF, DPYSL3, LPAR1, EFNA5, EPHA1, EPHB1, EPHB2, EPHB3, GPM6A, HAS3, HRG, KDR, LIMK1, SMAD3, CNOT2, NTRK1, NTRK2, NTRK3, OXT, P2RX7, PIP4K2A, PRKCA, PRKCQ, PROX1, PTPRJ, RALA, S100A10, SDC1, SDC4, SDCBP, SOX9, TAC1, TPBG, TSC1, TSG101, NR1H2, WNT11, HAP1, ITGB1BP1, NRXN3, NRXN1, PAN2, PDCD6IP, SORBS3, RAPGEF3, SEPT9, SYNPO |
2243 | GO:0006461 | 0.00 | 1.50 | 156.22 | 193 | 381 | protein complex assembly | ADD1, ADRB2, AP2B1, ALDOB, ANG, ANGPT1, APCS, BIRC5, AREG, ARHGAP6, ATRX, BAD, BBS4, BLK, CAPZA1, CAPZB, CASQ2, CCNB1, CD3G, CD40, CD59, CD74, CDC42, CLGN, CENPA, CENPE, CENPF, CHD4, AP2S1, COL16A1, COX15, CSNK1D, CTSZ, CYBA, CYLD, DARS, DDX3X, DIAPH1, DIAPH2, DNAH5, EFNA5, EIF4EBP1, EPRS, EPS8, EPS15, FANCA, FANCC, FGA, FGG, FLNA, CENPI, GFAP, GRIA1, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, H3F3B, HIST1H1A, HCLS1, NRG1, HIP1, UBE2K, HMGA1, HRG, HES1, HSPA4, HSPA8, HSP90AA1, IL1RAP, IL2RB, INSIG1, KPNB1, TNPO1, IPO5, LMAN1, SMAD1, SMAD3, SMAD6, NUP98, OTX2, PARK2, PDCL, CHMP1A, PIK3C2A, PPID, PPM1A, PPP2R1A, PPP2R1B, PPP6C, MAPK3, EIF2AK2, PSMD4, PSMD5, PSMD8, PSMD11, PTGER4, RAB1A, RBBP4, RDX, SELP, SET, SGK1, SH3BGR, SNAP25, SNCA, SOX9, SPAG1, SPTA1, SPTB, AURKA, STK11, STXBP1, SURF1, TAZ, TBCA, TBCD, TRAPPC10, TMOD1, TRAF1, CCT3, TSPY1, UVRAG, VBP1, VDAC2, ZNF148, ZNF207, CHAF1B, PICALM, HIST1H2BG, HIST1H2BL, HIST1H2BM, HIST1H2BF, HIST1H2BH, HIST1H2BO, HIST2H2BE, CUL3, IKBKAP, HAT1, CDC14A, USO1, CADPS, TNKS, RAB11A, SNAP23, LIN7A, HDAC3, SYNJ1, HIST1H2BJ, H1FX, LATS1, AIFM1, ZW10, REPS2, AURKB, ITGB1BP1, SNAP29, SLIT2, SLC9A3R1, KIF3B, ZFYVE9, NRXN1, SEC22B, GOSR2, PDE4DIP, NUP93, KNTC1, TOMM20, FARP2, SNAP91, KIAA0196, RANBP9, PREB, AKAP9, SEC24B, PPIH, SEC23A, ARFGEF1, CCT2, AVIL, CCT6B, CCT8, NRG3, SEC24A, FERMT2, ADRM1, UBE2C, STMN2, SLC7A9, CHEK2, OIP5, TWF2 |
2244 | GO:0000165 | 0.04 | 1.50 | 33.72 | 42 | 83 | MAPK cascade | APC, ATF3, AVP, BMP1, BMP6, BMP8B, CCR5, CRYBA1, DUSP1, EPHA2, EPHA7, FBLN1, GDF9, IL18, INHA, ITGAV, ITPKB, SMAD1, NRTN, PPP2R1A, PTPN6, PTPRJ, PTPRR, RGS2, RRAS, SMPD1, SORL1, SOX9, STYX, TSG101, SCG2, BMP15, ITGB1BP1, KLF4, SLC9A3R1, GDF15, RANBP9, ATP6AP2, RNF41, TNIP1, RGS14, STK38 |
2245 | GO:1903827 | 0.01 | 1.50 | 62.15 | 77 | 150 | regulation of cellular protein localization | ACTL6A, AKT2, APC, ARF6, BAD, BCL2, BID, BNIP3L, CAMK4, CASP8, CCNB1, CDC42, CHRM1, CSNK2A2, CTSK, DLG1, EPHA2, STOM, ERBB2, ACSL3, KAT2A, SFN, GPR26, NRG1, HES1, IFNG, ITGA3, ITGAX, ITGB1, OAZ1, OAZ2, PARK2, PCM1, PDPK1, PRKCI, MAPK8, PSMB7, PSMD8, PTN, PTPN1, PTPN14, RAC2, RB1, RDX, RNASE2, RPL28, SORL1, SREBF1, U2AF1, UBE2L3, VEGFA, VIL1, EZR, YWHAG, YWHAH, YWHAZ, ZBTB17, FZD5, BAP1, KCNAB2, CAMK1, DYNLL1, VAMP8, BECN1, RAB11B, NRXN1, CRIPT, C2CD5, FAM20B, BCL2L11, STX6, RAMP3, RAPGEF3, ARIH2, AGR2, SORBS1, RER1 |
2246 | GO:0044711 | 0.00 | 1.50 | 191.41 | 236 | 471 | single-organism biosynthetic process | ABCA1, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADORA2A, ADRB2, AP2A1, NR0B1, AKT2, ALDH3A2, AMPD1, AMPD2, ANG, ANGPT1, APLP1, AQP1, ARF1, ATM, ALDH7A1, ATR, AVPR2, C1QBP, C3, CALCR, CALM3, SCARB1, CLTC, CREBL2, CSNK1G2, CYP1A2, DDB1, DLD, DTYMK, LPAR1, EDNRA, EDNRB, EEF2, EIF5A, ESD, EXT1, EXT2, EXTL1, EXTL2, EXTL3, ACSL1, ACSL4, FDXR, GPC4, GPC5, FSHR, NR5A1, FUT8, KDSR, B4GALNT1, GALR1, GARS, B4GALT1, GHRH, GHRHR, GK, GPC3, GLB1, GLP1R, GMDS, GNAI3, GNAL, GNAS, GPC1, GPLD1, GRM8, GSS, GSTM1, GSTM2, GSTZ1, GUCA1A, GUCA1B, GUCA2A, GUCA2B, GUCY1B3, GUCY2C, GUCY2F, GYS2, GUCY2D, HADHA, HARS, HAS1, HAS2, HAS3, HEXA, HEXB, HSD11B1, HTR2C, IDH1, IGF1, IGF2, INPP4A, INPPL1, INSL3, LUM, CHST6, MGAT2, NTRK1, NTRK2, OAS1, OAS2, OCRL, ODC1, OMD, OGN, P2RX7, P2RY11, PBX1, ENPP1, PHKG1, PIGC, PIK3C2A, PIK3C2B, PIK3C3, PIK3CB, PIK3CG, PI4KA, PI4KB, PIP4K2A, PPP1CA, PPP1R3C, PPT1, PRKCA, PRKD1, PRKCQ, MAPK3, PRPSAP1, PTGER4, PTHLH, RAF1, RCVRN, REV3L, RPS27A, RRM1, RRM2, SDC1, SDC2, SDC4, ST6GAL1, SMPD1, SMPD2, UAP1, SRD5A1, TAZ, TNFRSF1A, CCT3, TUFM, UBB, UBA7, UFD1L, UGT8, VIP, VIPR2, WFS1, TRIM25, ZP3, EPM2A, PDHX, PIP5K1B, NSMAF, DYRK2, CUL4B, CUL4A, PIK3R3, DGKE, AGPS, MAPKAPK5, PDXK, HSD17B6, TNKS, DGAT1, B4GALT4, B4GALT3, B3GALT2, SUCLG1, INPP4B, SYNJ1, SGPL1, CPNE1, AURKB, VAPB, VAPA, B4GALT6, B4GALT5, CPNE6, CHST3, AKAP6, PIGL, GAL3ST1, TBPL1, MPDU1, GABBR2, GUCA1C, HS2ST1, SDC3, KIAA0101, PTDSS1, EPM2AIP1, FIG4, XYLB, HS3ST3B1, HS3ST3A1, HS3ST1, RBX1, GNE, PIGK, ABCC5, GPC6, COL4A3BP, TSFM, RAD50, CALCRL, RAMP2, B3GNT3, ST3GAL6, MAD2L2, CAP2, CAP1, AGPAT2, SLC35A1, CCT7, CCT4, CCT2, SORBS1, CCT8, CERS1, ACOT2, SLC35D2, KERA, B4GALT7 |
2247 | GO:0051179 | 0.01 | 1.50 | 63.35 | 80 | 176 | localization | PARP4, AMBP, BIN1, APLP1, ARR3, ASGR1, ASGR2, CBL, CD5, CD5L, CD6, ACKR2, CRYAB, DBI, DSC2, FABP2, FABP7, GATA4, GEM, GNAI3, HIP1, HP, IGF2R, INPPL1, LRMP, LRP3, LRPAP1, MAP6, CITED1, PPP1R12A, ORM2, ENPP3, PI4KB, RBM4, RBP1, RBP2, RLBP1, SET, SLIT1, SIGLEC1, SYP, SYPL1, TACC1, DYNLT3, TMPRSS2, TNNC1, TNNT2, ZFPL1, LAPTM5, ANP32A, DYSF, IKBKG, INPP4B, CPNE1, KALRN, USP6, SYNGR3, PDLIM7, CYTH2, TRIP10, TRIP4, CD163, CPNE6, CHST3, MPDU1, RIN1, ABCF2, ACTR1A, G3BP1, PRG4, CLEC10A, STK25, TACC2, RGS14, CSPG5, TBR1, MALT1, STON1, ZWINT, AKAP13 |
2248 | GO:0006820 | 0.00 | 1.49 | 90.15 | 111 | 218 | anion transport | ABCA1, ABCA2, ABCA4, AGXT, ALB, ABCD1, ANXA1, APOA1, APOA4, APOC2, AQP1, BDKRB2, CA1, CA4, CA5A, CA6, CACNB4, SLC25A20, CD36, SCARB1, CETP, AKR1C4, CPT1B, CPT2, SLC25A10, CTNS, ACE, FABP6, ACSL1, ACSL3, FOLR3, SLC37A4, GLS, GOT2, HBA1, HBA2, KCNJ10, KCNN4, NTRK2, ATP8B1, PRKAB2, ABCD3, RAB3A, RHAG, RXRA, SCP2, SLC1A6, SLC1A7, SLC2A2, SLC6A6, SLC6A7, SLC6A8, SLC6A11, SLC6A12, SLC6A13, SLC7A1, SLC7A4, SLC10A1, SLC10A2, SLC16A1, SLC25A1, SLCO1A2, SLC22A5, SNAP25, STXBP1, SYT1, TRPC4, TRPV1, XK, SLC7A5, SLC10A3, SLC4A4, ABCC3, SLC5A6, SLC13A2, SLC16A6, SLC16A5, SLC16A4, SLC6A5, SLC16A7, SLC22A6, SLC9A3R1, SLC22A8, SLC22A13, SLC4A8, ABCG1, SLC23A2, NR1H4, ABCC5, ATP9A, SLC25A13, SLC25A15, SLC35B1, ABCC4, SLC25A17, UNC13B, ARL6IP5, SLC35A1, SLCO1B1, GIPC1, STARD10, CPLX1, SLC22A7, SERINC3, SLC27A5, SLC27A4, SLC27A2, SLC7A9, PRAF2, CA5B, SLCO2B1 |
2249 | GO:0019220 | 0.00 | 1.48 | 101.92 | 126 | 256 | regulation of phosphate metabolic process | ADAR, ADARB1, AHSG, AMBP, APC, APLP2, APOA1, RHOH, ARR3, ATF3, BARD1, BDKRB2, CAV3, CCNE1, CDC25C, CDK4, CDKN2A, CDKN2C, CDKN2D, CHAD, CISH, CKS1B, CRY2, CRYBA1, DCN, DLG2, DLG3, DUSP1, DUSP4, EPHA2, ENSA, EPHA1, EPHB1, FBLN1, FECH, GNAQ, SFN, GP1BA, GPS2, HHEX, FOXA2, HPN, HRC, HRG, HSPB1, ITPKB, SMAD6, SMAD7, MEN1, PARK2, PCP4, ENPP1, PER1, PPP1R1A, PPP1R2, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PRKAB2, DNAJC3, PRPSAP1, PTPN6, PTPRJ, PTPRR, RAC2, RAD51, RANBP2, RB1, RBL1, RBL2, RGS2, RRAS, ATXN7, SERPINB3, SET, SORL1, SPINK1, STYX, TAF7, TARBP2, NR2F2, TNFAIP3, TSC1, TSC2, TSG101, TWIST1, UVRAG, EZR, YWHAG, AKAP1, IKBKAP, DYNLL1, URI1, KAT2B, SOCS3, DIRAS3, CCNE2, SOCS6, SLIT2, SLC9A3R1, EIF2AK3, GMFG, SFI1, PPP1R26, SMG7, NUAK1, RANBP9, CTDSP2, ATP6AP2, FARP1, RNF41, CTDSPL, TRIB1, TNIP1, CD2BP2, HEXIM1, RGS14, ZMYND11, ARPP19, PRDX3, UBE2C, CDC37, STRAP, AKAP13, STK38 |
2250 | GO:0007154 | 0.00 | 1.48 | 566.76 | 678 | 1532 | cell communication | AARS, ABCA4, ACADVL, ACTB, ACTG1, ADCYAP1R1, ADD1, ADRBK2, AGXT, AHR, ANG, ANGPT2, ANXA4, ANXA6, APBB1, APLP1, APOA4, APOC2, KLK3, ARF4, ARL4D, ARF5, RND3, ARL1, ARR3, ASGR2, ASNA1, ATOH1, ATP2A1, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATRX, AVPR1B, AVPR2, BAG1, ADGRB2, BBS2, BBS4, BCL2A1, BCL9, TNFRSF17, OPN1SW, BMX, BOK, DST, BRCA2, BRS3, BSG, BTK, BUB1B, CAPN5, DAGLA, CALCR, CAMLG, CAPS, CASP4, CASP9, CCK, KRIT1, CCNC, CCND3, CCNT1, CCNT2, CD2, CD3D, CD3G, CD5, CD6, CD7, CD9, TNFRSF8, SCARB1, CD37, ENTPD2, CD53, CD59, CD69, CD72, CD79B, CD151, CDA, CDC5L, CDC25C, CDH1, CDH6, CDH17, CDK4, CDK6, CDK8, CDK9, CENPA, CENPE, CENPF, AKR1C4, CHKA, AP3S1, CLCN6, TPP1, CLPS, CCR3, CCR8, ACKR2, LTB4R, COL4A3, COL16A1, CLDN3, CR1, CR2, ATF2, CREBL2, CRYAB, CSH1, CSNK1G3, CTLA4, CTSS, DGKA, DGKB, DGKQ, DCC, DCX, DDB1, DDX11, DEFA1, DHCR24, DIAPH1, DIAPH2, DMBT1, DOK1, DSP, E2F2, E2F4, E2F5, S1PR3, EDN2, EDNRB, CELSR2, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4EBP1, EIF4G1, EIF4G2, ELK1, ELK3, ADGRE1, EPHA1, EPHA3, EPHB2, EPHB3, ERG, ESRRG, ETV2, EXT1, EXT2, EXTL3, EYA2, ACSL1, EFEMP1, FCER1G, FCER2, FCGR1B, FCGR2A, FCGR2B, FCGRT, FCN1, GPC4, GPC5, FLT3LG, FPR2, FPR3, FRK, CENPI, GAST, FUT8, ACKR1, FYB, GABRE, GAP43, GCGR, NR6A1, OPN1MW, GEM, GFRA1, B4GALT1, GH2, GJB5, GMDS, GNA15, GNAQ, GNAT2, GNAZ, GNRH2, GNRHR, GOT1, CCR10, GPR3, GPR4, XCR1, GPR15, GPR17, GPR25, GPR26, GRID1, GRN, GRM8, CXCL1, CXCL2, CXCL3, GRPR, GTF2I, GUCY1B3, GUCY2C, H3F3B, HCK, HDGF, HIP1, HIVEP2, HLA-DQA1, NR4A1, HNF4G, HOXD3, HPGD, HSP90AA1, ICAM2, IDE, SP110, IFIT1, IFIT3, IGF2R, IL1R1, IL1RAP, IL10RA, IL11RA, IL12RB2, IL15RA, TNFRSF9, IMPA1, IMPA2, INCENP, INPP1, INPP4A, INSIG1, INSRR, IRF2, IRF5, ISG20, ITGA4, ITGA7, ITGA9, ITGAD, ITGAE, ITGAM, ITGAX, ITGB4, ITGB5, JUNB, CD82, KLK2, KLRB1, KLRC2, KLRC3, KLRD1, KLC1, KPNA1, KPNB1, KPNA4, KPNA5, KRT18, KRT19, LAMA5, LIMK1, LSP1, LTBP2, BCAM, TACSTD2, EPCAM, MAD2L1, SMAD1, DNAJB9, SCGB2A1, CIITA, FOXO4, PPP1R12A, PPP1R12B, SEPT2, NRTN, DDR2, NTS, NUP88, NUP98, OAS1, OAS2, OAS3, OR1D2, OR1F1, OR2C1, OR3A1, OR3A2, P2RY2, P2RY4, P2RY6, PAX2, PDC, PDE3A, PDE4B, PDE7A, PDE8A, PDE1B, PDGFRL, ENPP2, PF4V1, PGAM2, PIGR, PIK3C2A, PIK3C2B, PI4KA, PI4KB, PPP1R1A, PPP2R5D, PPP4C, SRGN, PRKAB2, PRKCI, PRKCSH, PRKG1, DNAJC3, PTAFR, TAS2R38, PTGDR, PTGER1, PTH1R, PTH2R, PTK7, PTPRD, PTPRM, RAB4A, RAB6A, RAB13, RAB27A, RAB27B, RABIF, RAB5C, RALA, RAN, RANBP2, RAP1GDS1, RAP2B, RARB, RBL1, RBM4, RBP1, RBP2, OPN1LW, PRPH2, RELB, DPF2, RGR, RLN1, RLBP1, RPS6, RPS6KB2, RPS19, RPS27, RREB1, CLIP1, RSU1, RXRA, RXRG, RYR1, RYR3, S100A1, SORT1, S100A6, S100A11, SAFB, TSPAN31, SCTR, SDC1, SDC2, SDC4, SEL1L, SELE, SEMA3F, SGK1, STIL, SKP1, SLIT1, SMARCC1, SMPD2, SP1, SPARC, SPN, SRMS, SRPK2, SSR1, STAC, STAT4, STAT5B, STK10, STRN, SULT1A3, T, TACR3, TAF7, TBL1X, NR2F1, NR2F2, TSPAN7, TPTE, NR2C2, TRHR, TRPC3, TUFT1, TNFSF4, TYROBP, UBA7, UBE2D1, UBE2D2, UPK1B, SCGB1A1, KDM6A, VIL1, VIM, TRPV1, LAT2, CORO2A, XPA, ZNF8, ZP2, IL1R2, FZD3, NUP214, CUL5, AAAS, ANP32A, RND2, MADCAM1, NRIP1, CLTCL1, USP9X, SMC1A, USP9Y, HIST1H4I, FZD9, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, OR1A1, OR1E1, OR1E2, OR1G1, OR3A3, SPARCL1, BCAR3, NSMAF, DYRK2, CUL4A, CUL2, CUL1, SORBS2, CDC42BPA, PIK3R3, IKBKAP, DGKE, COPS3, CAMK1, OR6A2, RFXANK, UNC5C, SSNA1, OASL, DCHS1, S1PR4, CTNNAL1, TNFSF13, ADAM15, TNFRSF10D, PEX11A, IL18RAP, IL1RL2, NRP2, HCAR3, KAT2B, ALDH1A2, NR1I2, SGPL1, WASF1, HIST1H3F, RPS6KA4, ATP6V0E1, PGLYRP1, RHBDL1, TAAR5, UBA3, DOK2, PSTPIP1, PRC1, ANGPTL1, DIRAS3, ATP6V0D1, SMC3, FIBP, RASSF9, ZW10, BUB3, REPS2, SLC24A1, DCLK1, AURKB, XPR1, VAPB, RPS6KA5, NUMBL, STK17B, STK17A, BCL7B, TAAR2, ATP6V1F, TRIP4, GLP2R, RAB9A, ECEL1, AKAP7, IL27RA, THEMIS2, BAG3, RAB3D, ATP6V1G1, BCAR1, GTPBP1, GOSR2, BRE, CDC42BPB, RAB36, AATK, GNA14, ZNF516, SDC3, NUP93, CEP57, SEMA3E, KNTC1, SLK, HDAC4, ZFYVE16, RAPGEF5, SNX17, KIAA0586, CKAP5, SPOCK2, KIAA0141, CUL7, ELMO1, GAB2, C2CD5, TRIL, NUAK1, P2RY14, OXSR1, NR1I3, NR1D2, CASP8AP2, NR2E3, ABI1, PARP2, TOM1L1, PTPRU, GPC6, COL4A3BP, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN2, TSPAN1, CTDSP2, ARPC2, SGK2, PREB, ARL4C, ARL4A, PDIA6, ARFRP1, EBI3, ABI2, WASF2, TNK2, CALCRL, RASGRP2, AKAP8, EFS, SIGMAR1, SEMA3A, IFITM3, PGRMC2, RBM14, CDC42EP2, IFI30, OLFM1, CAP2, CAP1, SEMA6C, SEMA6B, SEMA4B, BATF, PRDX4, ARPC1A, IFITM2, CDC42EP3, ERLIN1, TXNIP, PDPN, RASL10A, CXCR6, TNFSF13B, EBP, RRH, CNPY3, NRG3, CHL1, NUP50, AHCYL1, OR5I1, CCR9, GJB6, CD300C, PROKR1, BRD8, SEC61B, PDIA5, RAB40B, FERMT2, RAB32, KDELR3, IFT27, RAB35, RAB31, ADAP1, UPK1A, OGFR, WWP1, ADAMTS13, NUPL2, CIT, CD160, ZWINT, CDC42EP1, IL1RAPL1, CORO1A, RABL2B, RABL2A, ERLIN2, RASSF1, CHEK2, AKAP10, RASSF8, SEC63, NXPH4, NXPH3, GPR45, GPR182, OIP5 |
2251 | GO:0021953 | 0.05 | 1.47 | 36.70 | 45 | 88 | central nervous system neuron differentiation | PHOX2A, CACNA1A, CDK5, CHRNB2, DCC, DCX, EMX1, EPHA4, EPHB1, EPHB3, EVX1, FGF8, GNAQ, HOXC10, HPRT1, HES1, ISL1, NTRK2, OGDH, PTCH1, RAC1, RAC3, RYK, SALL1, SHH, SMARCC2, SOX1, SOX2, SOX4, SOX5, TAL1, CNTN2, NR2E1, TULP3, UBB, WNT1, EOMES, PHOX2B, DCLK1, SLIT2, RAPGEF2, OLIG2, SEMA3A, ATG7, TBR1 |
2252 | GO:1902532 | 0.01 | 1.47 | 74.38 | 91 | 179 | negative regulation of intracellular signal transduction | ABL2, AMBP, APC, RHOH, ATF3, BMP4, C1QBP, CALM3, CASP8, CASQ2, CAV3, CHAD, CISH, CYLD, DCN, DLG1, DUSP1, DUSP4, DUSP5, DUSP7, DUSP9, DYRK1A, EPHA2, ESR1, F2RL1, FBLN1, GP1BA, GPS2, RAPGEF1, ARHGAP35, GSTM2, HMGCR, IGF1, IGF1R, IL1B, IL10, ITGA3, ITGB1, ITPR1, MEN1, P2RX7, PDE3B, PER1, PHB, PPM1A, PPM1B, PPP2CB, PPP2R1A, PRKCA, PTPN6, PTPRJ, PTPRR, RASA2, RGS2, SERPINB3, SEC14L1, SFRP5, SMPD1, SORL1, SPINK1, TNFAIP3, TP73, TRIP6, TWIST1, EZR, CUL3, TNK1, RIPK1, TNFSF14, HDAC3, CPNE1, SOCS3, IL1RL1, ITGB1BP1, SOCS6, KLF4, SLIT2, SLC9A3R1, GSTO1, LITAF, RASSF2, NR1H4, RANBP9, RASA4, TNIP1, TRDN, OLFM4, STAMBP, RGS14, ZMYND11, STK38 |
2253 | GO:0010557 | 0.05 | 1.46 | 34.91 | 43 | 87 | positive regulation of macromolecule biosynthetic process | C1QBP, CD4, TNFRSF8, CDK4, CIRBP, CTGF, DAZ1, EEF2, EIF5A, ELAVL1, FCER1A, FCER2, FGFR4, GOLGA2, HAS2, PRMT1, HSPB1, ITGA2, KDR, PAWR, DNAJC3, PTAFR, PTGER4, RBM3, RPS4X, RPS6KB2, CCL20, CCL21, SPN, SYK, TARBP2, NR2F1, DYRK2, SERPINB7, EIF2B5, EPM2AIP1, HDAC6, EBI3, PRG3, ARFGEF1, SORBS1, KHDRBS1, GLMN |
2254 | GO:0034976 | 0.03 | 1.46 | 48.30 | 59 | 116 | response to endoplasmic reticulum stress | AARS, ACADVL, ADD1, ASNA1, ASNS, ATF3, CCND1, TPP1, CTH, DDX11, EEF2, EIF2S1, EP300, EXTL3, HDGF, DNAJB2, IFNG, JUN, DNAJB9, ATXN3, PPP2CB, EIF2AK2, DNAJC3, PSMC1, PSMC3, PSMC4, PSMC5, SEL1L, SGTA, SHC1, SSR1, SULT1A3, UFD1L, TRIM25, ZBTB17, RNF103, SRPX, EIF2B5, USP13, USP14, ATP6V0D1, VAPB, GOSR2, CUL7, COL4A3BP, CTDSP2, PREB, PDIA6, MARCH6, AGR2, ERN2, ERLIN1, USP19, SEC61B, PDIA5, OS9, KDELR3, ERLIN2, SEC63 |
2255 | GO:0022607 | 0.00 | 1.45 | 503.88 | 601 | 1222 | cellular component assembly | ABCA1, ABL2, ACADL, ACADS, ACAT1, ACHE, ADAR, ADD1, ADRB2, ADSL, AP2B1, AHR, ALAD, ALDOB, BIN1, ANGPT1, ANXA2, ANXA5, ANXA6, APCS, BIRC3, BIRC5, APOA1, APOA4, AQP1, AREG, ARF1, ARF6, ARG1, ASL, ATM, ATR, ATRX, BAD, ADGRB2, BAX, BBS1, BBS2, BBS4, BICD1, BID, BIK, BLK, BRCA1, KLF5, C1QBP, CACNA1A, CAMK2G, CAPZA1, CAPZB, CASP8, CASQ2, CAT, CAV2, CAV3, CCK, CCNB1, CD3G, CD36, ENTPD2, CD40, CD59, CD74, CDA, CDC42, CDK5, CDKN2A, CLGN, CENPA, CENPE, CENPF, CFL2, CHD4, CHRNB2, CHRNB4, CIRBP, AP2S1, CLNS1A, COL1A1, COL6A2, COX15, CLDN7, CRYAB, CRYZ, CSF2, CSNK1D, CTGF, CTH, CTSZ, CYBA, CYLD, DARS, DDX1, DDX3X, DDX6, DECR1, DHPS, DIAPH1, DIAPH2, DNM1, DNAH5, DYNC1H1, DNM2, DPAGT1, DPYSL3, E2F4, S1PR1, LPAR1, CELSR2, EIF2S3, EPHA2, EIF4EBP1, EMP1, EMP2, EMP3, STOM, EPHA1, EPHA7, EPHB1, EPHB2, EPHB3, EPRS, EPS8, EPS15, F2RL1, FANCA, FANCC, ACSL3, FECH, FGA, FGD1, FGG, FLOT2, CENPI, GAP43, GFAP, GHSR, GLRA1, GLRA2, GLRB, GLS, GLUL, GOLGA2, GPC1, GPM6A, GPX3, GRB2, GRB7, GRIA1, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, H3F3B, HIST1H1A, HSD17B10, HBA1, HBA2, HCK, HCLS1, NRG1, HIP1, UBE2K, HMGCL, HMGCR, HMGA1, ONECUT1, HPRT1, AGFG1, HES1, HSPA4, HSPA8, HSP90AA1, ICAM1, IDE, IGF1R, IL1RAP, IL2RB, TNFRSF9, IMPDH2, INS, INPPL1, INSIG1, EIF3E, IRAK1, ITGB5, ITPR3, JUN, KCNA1, KCNA2, KCNA3, KCNA4, KCNA5, KCNA10, KCND2, KCND3, KCNJ2, KCNJ12, KCNS1, KCNS2, KCNS3, KIT, KPNB1, TNPO1, IPO5, KRT19, LCAT, ABLIM1, LIMK1, LMAN1, TACSTD2, SMAD1, SMAD6, RAB8A, MYO1B, NUBP1, SEPT2, CNOT2, NRCAM, NTRK1, NTRK2, NTRK3, NUP98, OAS1, OAT, OCRL, ODF2, OPHN1, OTC, OTX2, OXA1L, OXT, P2RX3, P2RX4, P2RX7, PAM, PAWR, PDCL, PCM1, CHMP1A, PEX14, ATP8B1, PFN1, PFN2, PIK3C2A, PIK3C3, PIP4K2A, PLN, PPID, PPM1A, PPP2R1A, PPP2R1B, PPP5C, PPP6C, PRKAA1, PRKAR1A, PRKCE, PRKCQ, PRKCZ, MAPK3, MAPK8, EIF2AK2, PROX1, PSMC1, PSMC3, PSMC4, PSMD4, PSMD5, PSMD8, PSMD11, PTGER4, PTPRD, PEX5, RAB1A, RAC2, RAC3, RAD51, RAD51B, RAD51D, RAF1, RALA, RAP1GAP, RAP2A, RB1, RBBP4, RDX, RFX3, RFX4, RGS2, RPGR, RPL3L, RPL6, RPL10, RPL11, RPL23A, RPL24, RPL38, RPS3, RPS19, RPS27, RPS27A, RRM1, RRM2, CLIP1, RXRA, RXRG, RYK, RYR3, CCL21, CCL24, SDC1, SDCBP, SELP, SEMG1, SET, SRSF1, SRSF5, SRSF6, SFSWAP, SGK1, SH3BGR, SHMT1, SHMT2, SIX1, SLC6A4, SLC34A1, SLC22A1, SLIT1, SNAP25, SNCA, SNRPC, SNRPD1, SNRPD2, SNRPE, SNRPF, SOD2, SOX12, SPAG1, SPAST, SPTA1, SPTB, SRPK2, AURKA, STK11, STXBP1, STXBP3, SURF1, SYT1, TAC1, TAF2, TAF7, TAL1, TARBP2, TAZ, TBCA, HNF1A, TRAPPC10, TMF1, TMOD1, TNFAIP3, TNFRSF1A, TNNT2, TP73, TPBG, TRAF1, TRAF2, CCT3, TSG101, TSPY1, TWIST1, UBB, SUMO1, USP4, NR1H2, CLRN1, UVRAG, VBP1, VDAC2, VIL1, EZR, WNT1, XRCC2, YWHAZ, ZNF148, ZNF207, ALMS1, RAB7A, ARHGEF5, STAM, CSRP3, FOSL1, IFT88, SF3A2, CLPP, CHAF1B, HIST1H4I, PICALM, CDC45, HIST1H2BG, HIST1H2BL, HIST1H2BM, HIST1H2BF, HIST1H2BH, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SRPX, SOAT2, CUL3, OGT, OFD1, IKBKAP, HAT1, CDC14A, PRPF18, DENR, TNFSF11, USO1, CADPS, TP63, TNKS, EIF3A, EIF3B, EIF3D, EIF3F, EIF3G, EIF3J, BECN1, SRSF9, DGAT1, TRADD, RIPK1, HRK, RAB11A, SNAP23, LIN7A, CFLAR, HDAC3, AKAP4, SYNJ1, CDC123, BCL10, BSN, WASF1, HIST1H3F, HIST1H2BJ, H1FX, HAP1, TAF1B, LATS1, ATP6V0D1, PRPF3, AIFM1, SCAF11, ZW10, REPS2, AURKB, S1PR2, SNAP29, SLIT2, SLC22A6, RAB33A, SLC9A3R1, NRXN3, KIF3B, ZFYVE9, NRXN1, NRXN2, GRHPR, CIAO1, EIF2AK3, PICK1, ATG5, ONECUT2, TBPL1, BAG4, GMFG, SEC22B, GOSR2, FEZ2, IQCB1, PDE4DIP, CEP135, NUP93, CEP57, USP6NL, KNTC1, CCP110, IFT140, HDAC4, BCLAF1, KIAA0586, IST1, TOMM20, SPOCK2, RB1CC1, KIAA0753, FARP2, SNAP91, FIG4, KIAA0196, PAN2, WDR1, PDCD6IP, BCL2L11, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, NUBP2, ARPC2, PREB, AKAP9, ABI2, TRIM28, AASS, FARP1, WASF2, SORBS3, STAM2, ABCC4, CCNO, IKZF1, TRIM22, ABCA7, RAPGEF3, CD2BP2, TUBGCP3, SEC24B, RBM14, CDC42EP2, OLFM1, VAV3, BAIAP2, PPIH, EIF3M, SEC23A, STK25, UNC13B, ARPC1A, OLFM4, CXCL13, ARFGEF1, CCT2, USP16, CDC42EP3, PDLIM5, CTCF, AVIL, CCT6B, CCT8, USP39, NRG3, STAG3, SRSF10, SEPT9, SEC24A, MALT1, DHRS4, TXNL4A, EHD1, SF3A3, TMED10, RAB32, UPK1A, ADRM1, CPSF6, UBE2C, STMN2, TPPP, KIF3A, CDC42EP1, SLC7A9, IL1RAPL1, CORO1A, WDR45, PSIP1, STRAP, BAZ2A, CHEK2, SNF8, ATXN2L, OIP5, TWF2, SYNPO |
2256 | GO:0065009 | 0.05 | 1.45 | 36.56 | 45 | 94 | regulation of molecular function | NR0B1, ATP1A2, FXYD2, CACNB4, CASQ2, CMKLR1, CYLD, STOM, FLNA, GRK6, HCK, HRC, PRMT2, KCNE1, KCNQ1, KCNS1, KCNS2, PBX1, PDE4B, PDE4D, PTCH1, PTGIS, PTHLH, PTPN3, RNF2, SCN2B, SCN4B, SFRP4, SFRP5, TAF6, TNFSF4, YWHAH, FZD6, NR0B2, HDAC3, TAX1BP1, RAB9A, NRXN1, CACNG2, SIVA1, TAF6L, CTCF, AHCYL1, ZNF234, WWP2 |
2257 | GO:0016458 | 0.02 | 1.45 | 51.75 | 63 | 124 | gene silencing | ADAR, DNMT1, DNMT3A, DNMT3B, HIST1H2AE, HIST1H2AD, H2AFZ, H3F3B, HMGA1, KCNQ1, SMAD1, SMAD3, CNOT2, NUP88, NUP98, CHMP1A, PHF2, RAN, RANBP2, RBM3, RBM4, SUV39H1, TARBP2, TBP, TSN, UBTF, ZFP36, NUP214, AAAS, HIST1H4I, CDC45, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, FKBP6, HAT1, PRKRA, HIST1H3F, HIST1H2AG, TAF1C, TAF1B, TAF1A, RQCD1, CNOT8, NUP155, NUP93, PUM1, NUP50, NUPL2, BAZ2A |
2258 | GO:0006790 | 0.01 | 1.45 | 73.16 | 89 | 176 | sulfur compound metabolic process | ACLY, ANGPT1, BHMT, BTD, CACNA1A, COMT, CPS1, CTNS, DLD, DNMT1, DNMT3A, DNMT3B, DPEP1, ESD, EXT1, EXT2, EXTL1, EXTL2, EXTL3, ACSL1, ACSL3, ACSL4, GPC4, GPC5, GAMT, B4GALT1, GGT7, GPC3, GOT1, GPX1, GSS, GSTM1, GSTM2, GSTZ1, HLCS, HMGCL, HSD17B4, IDH1, IGF1, CHST6, MGST2, OGDH, PCCA, PDK4, PPT1, SDC1, SDC2, SDC4, SLC25A1, SMS, SNCA, SOD1, SP1, STAT5B, ELOVL4, PAX8, PDHX, TPST2, TPST1, DGAT1, B4GALT4, B4GALT3, SUCLG2, SUCLG1, SUCLA2, VNN2, VNN1, SLC5A6, KYNU, B4GALT6, B4GALT5, GSTO1, CHST3, SDC3, SPOCK2, HS3ST4, HS3ST3B1, ACOT8, GPC6, AASS, CHST4, GLYAT, AKR1A1, B3GNT3, ST3GAL6, AHCYL1, ACOT2, SLC35D2, B4GALT7 |
2259 | GO:0009893 | 0.00 | 1.44 | 151.89 | 185 | 397 | positive regulation of metabolic process | ACTA2, ACTB, ADAR, ADRBK1, ALDH1A1, ALDOB, AMPH, APC, ARF1, ARHGAP4, ARHGAP5, ARHGAP6, ARHGDIB, ARHGDIG, ARL1, ATP1B3, AVPR1B, BARD1, PRDM1, BNIP2, CBLB, CDK6, RCBTB2, CHN1, CHN2, CLPS, CSNK2A1, CYP27B1, DHFR, EDN2, EIF2B1, EPHA2, EPHA1, FGD1, FOXD1, GCGR, GDI1, GDI2, GPC3, GM2A, GNA15, GNAQ, GNAT1, FFAR1, ARHGAP35, CXCL1, H3F3B, HOXD3, AGFG1, AGFG2, TNC, ITGA3, ITPR1, ITPR2, ITPR3, LLGL2, CD46, MGST2, ATXN3, PPP1R12B, OAZ1, OAZ2, OCRL, OPHN1, PDE1B, PFN1, SERPINB9, MAPK8, RAB3A, RAB4A, RABIF, RAP1GAP, RAP1GDS1, RFC1, RGS1, RGS2, RGS10, RGS13, RGS16, RPGR, RPS2, RPS6KA2, RPS19, RSU1, RYR2, S100A10, SBF1, SFTPB, SIPA1, SLC6A4, SORL1, SOS2, SRPK2, STAR, CDKL5, TBCD, TNNT2, TRIO, TSC1, KDM6A, VAV1, VIM, WRN, XRCC4, RAB7A, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, NR0B2, CUL4B, PRKRA, S1PR4, TNFSF12, RGS11, RGS9, ASAP2, ALDH1A2, ARHGEF7, EIF2B4, EIF2B3, EIF2B2, HERC2, HIST1H3F, USP13, KALRN, TAF1C, TAF1B, TAF1A, RABEP1, DDX21, CYTH3, CYTH2, TRIP10, GTF3C4, ARHGAP29, QKI, ARHGEF6, STXBP5L, GMFG, SEC22B, RIN1, RIMS2, USP6NL, ACAP1, RAPGEF5, RGP1, ARHGEF17, FARP2, SGSM2, DENND4B, RABGAP1L, ARHGAP25, SH2D3C, SH2D3A, UBA2, FARP1, RASGRP2, DENND4A, APC2, CDC42EP2, OLFM1, AGR2, CXCL13, ARFGEF2, CDC42EP3, RGS14, EDAR, DBF4, ADAP1, RAPGEF4, CDC42EP1, AKAP13, SNF8 |
2260 | GO:0006470 | 0.03 | 1.43 | 48.69 | 59 | 117 | protein dephosphorylation | ACP2, ADORA1, AGTR2, BCL2, CALM3, CAMK2G, CRY2, DLG1, DLG2, DLG3, ENSA, GPLD1, HPN, IFNG, ITGA1, ITGA2, SMAD3, PPP1R12A, PAWR, PPM1A, PPM1B, PPM1G, PPP1CA, PPP1R2, PPP1R3C, PPP1R7, PPP2CB, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PPP4C, PPP3R1, PPP5C, PPP6C, EIF2AK2, PTPRN, SBF1, SET, SMPD1, STYX, TSC1, AKAP1, SYMPK, PPM1D, URI1, RGN, CTDP1, AKAP6, BAG4, DLGAP5, SFI1, PPP1R26, NUAK1, CTDSP2, FARP1, CTDSPL, CD2BP2, ARPP19 |
2261 | GO:0007049 | 0.00 | 1.43 | 91.56 | 111 | 226 | cell cycle | ADARB1, AHR, ANXA11, ARF6, ARL2, ARNTL, BAD, BAX, CDK8, CHAD, CISH, CREBL2, CYLD, DCN, SEPT1, DNMT3A, DTYMK, DYRK1A, E2F2, E2F5, CENPI, GAK, GNAI1, GNAI3, SFN, GP1BA, GPS2, HSPA8, ING1, JUN, JUNB, JUND, KRT18, CDK16, PFDN1, PPP1CA, MAPK3, DNAJC3, PTCH1, RAB1A, RBL1, RBL2, RGS2, RNF2, RPS6KA1, RPS6KA3, RPS27, RRM1, SDCBP, SET, SRSF5, SGK1, SIAH1, SIAH2, STAT3, CDKL5, STK10, SUV39H1, TACC1, NR2C2, PTP4A1, CDK2AP1, CHAF1B, HIST1H4I, BAP1, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CAMK1, BLZF1, MADD, USO1, CDKL1, CDK5R2, SOCS3, UBA3, DIRAS3, EXO1, SOCS6, GMFG, WTAP, CROCC, PUM1, UTP14C, SLK, KIAA0101, RASSF2, RB1CC1, OXSR1, USP3, DMTF1, CASP8AP2, TRIB1, CCNO, IKZF1, HMG20B, STK25, TXNIP, USP39, ZMYND11, SEPT9, CCNI, CDC37, MAP4K5, TUSC2 |
2262 | GO:0044702 | 0.00 | 1.43 | 181.10 | 218 | 442 | single organism reproductive process | ACOX1, ACVR1, ADCY3, ADCYAP1R1, ADRB2, AMHR2, BIRC3, AREG, ARNTL, ATM, AXL, BAD, BBS2, BBS4, BIK, BMP6, BMPR1A, BOK, BRCA2, BRDT, BTG1, CASP5, CCIN, CCNB1, CD9, CDC20, CDC25C, CLGN, CFTR, CLU, COL9A3, CXADR, CYLC1, DAZ1, ACE, DHCR24, DIAPH2, DLD, DNM2, DNMT3A, DUSP1, PHC2, CELSR2, ERCC1, ERCC4, ETS1, ETV5, FANCA, FANCC, FANCD2, FGF8, FGF9, B4GALNT1, GAMT, GATA3, GATA6, NR6A1, B4GALT1, GLRA1, GLRB, GOLGA2, GPR3, HIST1H1T, HIST1H1A, HAS1, HAS2, HEXB, HMGCS1, HOXD11, AGFG1, HSD17B3, IDH1, IGF2R, IL1A, ING2, INSL3, LIMK2, LRMP, SMAD1, CD46, SMCP, MEA1, MFGE8, MKI67, NUMA1, ODF1, ODF2, OR1D2, CLDN11, OVGP1, OVOL1, PAFAH1B2, PAFAH1B3, SERPINA5, CDK16, PDE3A, PGAM2, PPP2R1A, PRKACA, PRKACB, PRKACG, PRKAR1A, PRM2, PTAFR, PTN, RAD1, RAD51, RAD51B, RAD51D, RBBP8, RGS2, RNF2, RPS6KA2, RRM1, SALL1, SBF1, SIAH1, SLC6A4, SMARCA2, SMARCA4, SOX2, SOX3, SPAG1, SPAG4, SPAM1, SPINK1, SRD5A1, SRY, SSTR2, SSTR3, STAR, AURKA, STYX, T, TAF4B, TARBP2, TBP, TNP2, TOP2A, NR2C2, CCT3, TRPC3, TRPM2, TSPY1, TYRO3, UBB, ZAN, WNT2B, XRCC2, ZNF35, ZNF148, ZP2, DNALI1, CSDE1, AAAS, IFT88, USP9X, SMC1A, USP9Y, UTF1, TPST2, FKBP6, AKR1C3, PDE5A, DYNLL1, ADAM15, AKAP4, EIF2S2, HERC2, RNF8, RGN, SMC3, FAM50A, EXO1, ZW10, BUB3, QKI, PICK1, ADAMTS2, GAL3ST1, TBPL1, CLOCK, SPAG6, PUM1, CEP57, UTP14C, SPATA2, KIAA0196, BCL2L10, BCL2L11, SMC4, ACTR2, RAD50, IRX5, FSTL3, CITED2, SEMA3A, TUBGCP3, CRTAP, DEAF1, PRDX4, CCT7, CCT4, CCT2, CCT6B, CCT8, STAG3, STAG2, PTTG2, ADAM28, PRSS21, CCNI, PIM2, SOX30, HSF2BP, CIT, PTGDR2, PHB2 |
2263 | GO:0061726 | 0.03 | 1.43 | 53.00 | 64 | 127 | mitochondrion disassembly | ACTL6A, ADRB2, ANXA5, BNIP3, BNIP3L, TSPO, C5, CA7, CAPS, CDKN2A, COX8A, CSNK2A2, CTSK, EIF2S1, CTTN, STOM, FANCC, FCGR3B, SLC37A4, BLOC1S1, KAT2A, HIF1A, HK2, KCNK3, KRT15, MDH1, NTHL1, PARK2, PGK2, SERPINB10, PRKG1, RPL28, RPS27A, SFRP4, SLCO1A2, SLC22A3, SNRPD1, SNRPF, SREBF1, STAT2, NR2C2, U2AF1, UBB, ZBTB17, ZNF189, FZD5, CHAF1B, BECN1, CHST3, ATG5, NUP93, RIMS3, PHYHIP, IST1, TOMM20, FGFBP1, HDAC6, TOMM40, ATG7, CSPG5, HSF2BP, CDC37, WDR45, ADAMTS7 |
2264 | GO:0050808 | 0.03 | 1.42 | 56.34 | 68 | 135 | synapse organization | ACHE, ATP2B2, ADGRB2, CACNA1A, CACNA1S, CACNB4, CDC20, CDC42, CDH1, CDK5, CHD4, CHRNB2, COL4A5, CTNNA2, CTNND2, EFNA5, EPHA7, EPHB1, EPHB2, EPHB3, ERBB2, ETV5, F2R, FNTA, GDNF, GHSR, GLRA2, GLRB, GPM6A, NRG1, TNC, NRCAM, NTRK1, NTRK2, NTRK3, OXT, PCDHGC3, RELN, PTN, PTPRD, RAB3A, RYK, SIX1, SLIT1, SNCB, SNCA, SNTA1, CNTN2, TNR, TPBG, TSC1, FZD5, CAMK1, BSN, NRXN3, NRXN1, NRXN2, CRIPT, SEMA3E, FRMPD4, SPOCK2, FARP1, CACNG2, SLC9A6, UNC13B, PDLIM5, RER1, IL1RAPL1 |
2265 | GO:0006325 | 0.00 | 1.42 | 133.00 | 160 | 320 | chromatin organization | ACTB, ACTL6A, APBB1, ATM, RERE, CCND1, BMI1, BRCA1, BRCA2, CCNB1, CDK4, CDK9, CHD1, CHD2, CHD4, ATF2, DDB1, DDB2, DNMT1, DNMT3A, DNMT3B, PHC1, EP300, EYA4, ESR1, EYA1, EYA2, EYA3, EZH1, GATA3, GCG, KAT2A, GFI1, GPS2, HIST1H2AE, HIST1H2AD, H2AFZ, HLCS, HMGN1, FOXA2, PRMT2, PRMT1, IL1B, ING1, ING2, ISL1, JARID2, MEN1, PER1, PHB, PHF2, PPP5C, PRKAA1, PRKCA, PRKCB, PRKD1, MAPK3, MAPK8, RAG1, RAG2, RB1, ARID4A, RBL1, RBL2, REST, RNF2, SAFB, SALL1, SATB1, ATXN7, SETMAR, SFPQ, SKP1, SNAI2, SMARCA1, SMARCA2, SNCA, SOX1, SOX2, SREBF1, AURKA, SUPT4H1, SUPV3L1, SUV39H1, TAF5, TAF7, TBL1X, TBP, TOP1, TRPS1, TTF1, TWIST1, UBTF, UCN, KDM6A, VEGFA, VRK1, WHSC1, PRDM2, BRPF1, BRD3, KDM5C, KDM5D, BAP1, CDC45, HIST1H2AK, HIST2H2AC, CUL4B, OGT, IKBKAP, CBX4, TP63, EED, SAP30, HDAC3, KAT2B, HIST1H2AG, RPS6KA4, TAF1C, TAF1B, TAF1A, AURKB, RPS6KA5, TRIP12, HMGN3, GTF3C4, ATG5, CHD1L, CLOCK, BRE, KDM4A, VPRBP, USP34, SETD1A, HDAC4, RNF40, SETDB1, SUPT7L, USP3, NR1H4, HDAC6, SAP18, IKZF1, HMG20B, HMG20A, RBM14, CARM1, ATG7, USP16, TRIM16, TAF6L, ZMYND11, SRCAP, RUVBL2, ARID5A, BRD8, WDR5, PRDM7, WDHD1, CBX3 |
2266 | GO:0016570 | 0.01 | 1.42 | 89.62 | 108 | 215 | histone modification | ACTL6A, APBB1, ATM, BRCA2, CCNB1, CDK9, ATF2, DDB1, DDB2, PHC1, EP300, EYA1, EYA2, EYA3, EZH1, GATA3, GCG, KAT2A, GFI1, HIST1H1B, HLCS, PRMT2, PRMT1, IL1B, ISL1, MEN1, PER1, PHB, PHF2, PPP5C, PRKAA1, PRKCA, PRKCB, PRKD1, MAPK3, MAPK8, RAG1, ARID4A, REST, RNF2, SALL1, SATB1, ATXN7, SETMAR, SFPQ, SKP1, SNAI2, SREBF1, AURKA, SUV39H1, TAF5, TBL1X, TRPS1, KDM6A, VEGFA, VRK1, WHSC1, PRDM2, BRPF1, KDM5C, KDM5D, HIST1H4I, BAP1, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4B, OGT, HAT1, EED, HDAC3, KAT2B, RPS6KA4, RNF8, BAZ1B, AURKB, RPS6KA5, GTF3C4, CLOCK, VPRBP, USP34, SETD1A, HDAC4, RNF40, SETDB1, SUPT7L, USP3, NR1H4, HDAC6, RBM14, CARM1, USP16, TRIM16, TAF6L, CTCF, SRCAP, RUVBL2, ARID5A, BRD8, WDR5, PRDM7, BAZ2A |
2267 | GO:0034765 | 0.02 | 1.42 | 61.30 | 74 | 148 | regulation of ion transmembrane transport | ATP1A2, FXYD2, HCN2, CACNA1A, CACNA1B, CACNA1E, CACNA1F, CACNA1S, CACNA2D1, CACNB4, CACNG1, CYBA, DIAPH1, DLG1, STOM, HRC, KCNA1, KCNA2, KCNA3, KCNA4, KCNA10, KCND2, KCND3, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ12, KCNJ13, KCNJ14, KCNJ15, KCNJ16, KCNS1, KCNS2, KCNS3, PAWR, PDE4B, PDE4D, PIK3C2A, PIK3CG, FXYD3, PLN, PRKACA, PRKCE, PRKD1, PTPN3, PTPN6, SCN1A, SCN2B, SCN3A, SCN8A, SCN10A, SEMG1, SLC8A1, SLN, SPINK1, YWHAH, SLC30A1, KCNAB2, KCNK5, KCNAB3, SLC9A3R1, NRXN1, KCNK6, ATG5, OXSR1, HCN4, CACNG2, AHCYL1, WWP2, CORO1A, SCN11A |
2268 | GO:0006575 | 0.04 | 1.42 | 44.77 | 54 | 108 | cellular modified amino acid metabolic process | ASS1, ALDH7A1, CCBL1, CKM, CRYM, CTNS, DHFR, DHPS, DIO1, DIO2, DIO3, SARDH, DNMT1, DNMT3A, DNMT3B, GAMT, GATA3, GGT7, GOT2, GPX1, GSS, GSTM1, GSTM2, GSTZ1, HPN, IDH1, IDO1, MGST2, OTC, P4HA1, ALDH18A1, SHMT1, SHMT2, SLC5A5, SLC6A8, SOD1, STAT5B, TYMS, PAX8, SLC25A16, ALDH4A1, GGH, VNN2, VNN1, SLC5A6, KYNU, P4HA2, GSTO1, PTDSS1, CRTAP, PRDX4, AHCYL1, ALDH1L1, SERINC3 |
2269 | GO:0019538 | 0.00 | 1.42 | 93.99 | 114 | 246 | protein metabolic process | ACY1, AEBP1, ALB, APOC2, ASGR2, CAPN5, CAPN1, CASP4, CASP5, CASP6, CASP10, SCARB1, CEBPE, CETP, CLCA1, COL2A1, COL11A1, CPA1, CPD, CPS1, VCAN, CTSD, CTSE, DLD, DPP4, DPP6, EXTL2, GPC4, GPC5, GFAP, GGT7, GHRHR, GPC1, GZMH, GZMK, HEXA, HP, IDS, IDUA, IHH, IL1RAP, KLK1, KLK2, LCAT, LTA4H, MEP1A, MGMT, ODC1, OLR1, PCSK6, CHMP1A, PEPD, PGC, PREP, SRGN, PRG2, KLK7, PRSS8, PTCH1, PTHLH, RFX4, RNPEP, SDC1, SDC2, SGSH, SPG7, ST14, TAF2, TMPRSS2, TPSAB1, UQCRC1, UQCRC2, XPNPEP1, SHFM1, CUBN, IFT88, LTBP4, TP63, ADAM19, ADAM15, GGH, CPNE1, RHBDL1, AIP, PCSK7, NUMBL, ZFYVE9, LIPG, TMPRSS11D, ECEL1, CHST3, ADAMTS4, ADAMTS3, ADAMTS2, ADAMTS1, SDC3, ADAMTSL2, SCRN1, KIAA0141, JOSD1, HS3ST4, HS3ST3B1, DPP3, GPC6, PRSS16, CSPG5, CORIN, CAPN9, ADAM28, PRSS21, KLK11, CAPN11, CAPN10, CTRC |
2270 | GO:0019221 | 0.03 | 1.41 | 52.24 | 63 | 128 | cytokine-mediated signaling pathway | ANGPT1, BAD, BBS2, BBS4, CHAD, CISH, CNTF, CSF2RB, DCN, ECM1, EDN2, EIF4A1, EIF4A2, EIF4E, EIF4G1, EIF4G2, EREG, F3, ACSL1, FLT3, GP1BA, IFNW1, IL1A, IL1B, IL1RAP, IL2RA, IL2RB, IL2RG, IL10RA, IL11RA, IL12RB2, IL15RA, KIT, KPNA1, KPNB1, KPNA4, KPNA5, KRAS, NUP88, NUP98, PPM1B, PTPRN, RANBP2, STAT3, STAT4, STAT5B, UBA7, LRP8, PXDN, IL1R2, NUP214, AAAS, IL18R1, RQCD1, IL1RL1, NUMBL, SOCS6, IL27RA, NUP155, NUP93, EBI3, NUP50, NUPL2 |
2271 | GO:0044712 | 0.00 | 1.41 | 108.04 | 130 | 266 | single-organism catabolic process | ACHE, ACTL6A, ADORA1, ADRB2, AMBP, ANXA5, AOX1, APOA1, APOC2, APOH, STS, BLVRA, BLVRB, BNIP2, BNIP3, BNIP3L, TSPO, C5, DAGLA, CA7, CAPS, CD44, CDA, CDKN2A, CLPS, COX8A, CSNK2A2, CYP1A2, CYP2A6, CYP3A4, ACE, DHPS, DPEP1, DPYD, TYMP, EIF2S1, CTTN, ENPEP, STOM, FABP2, FABP6, FABP7, FANCC, FCGR3B, SLC37A4, GALC, BLOC1S1, KAT2A, GPC1, GPLD1, DNAJB2, IDH1, IL1B, KCNK3, KRT15, LIPA, DNAJB9, MDH1, ATXN3, PAFAH1B2, PAFAH1B3, PAFAH2, PARK2, SERPINB10, PIK3C3, PIK3CG, PPT1, PRKACA, PRKACB, PRKACG, PRKCE, PRKG1, PSMC1, PSMC3, PSMC4, PSMC5, RPL28, RPS27A, SEL1L, SFRP4, SGTA, SLC9A1, SLCO1A2, SLC22A3, SNRPD1, SNRPF, SREBF1, STAT2, NR2C2, U2AF1, UBB, UFD1L, UGT2B4, WFS1, YWHAH, TRIM25, ZBTB17, ZNF189, RNF103, FZD5, RAB7A, CHAF1B, HSD17B6, BECN1, SGPL1, USP13, USP14, LIPG, CHST3, ATG5, NUP93, RIMS3, PHYHIP, IST1, TOMM20, FGFBP1, HDAC6, MARCH6, TOMM40, ATG7, SPTLC1, ERLIN1, USP19, SEC61B, OS9, HSF2BP, CDC37, WDR45, ERLIN2, ADAMTS7 |
2272 | GO:0036211 | 0.00 | 1.39 | 914.78 | 1050 | 2192 | protein modification process | ABCA1, ABL2, ABO, ACP1, ACP2, ACTL6A, ACVR1, ACVR1B, ACVR2A, ACVR2B, ACVRL1, ADAM10, ADAR, ADARB1, ADCY1, ADCY3, ADCY6, ADCY7, ADCY9, ADH5, ADORA1, ADPRH, PARP4, ADRA1B, ADRA2C, ADRB2, ADRBK1, ADRBK2, AGTR2, AKT2, ALK, AMBP, AMHR2, ANG, ANGPT1, ANXA1, ANXA2, APBB1, APC, BIRC3, XIAP, BIRC5, APLP2, APOA1, AREG, ARF4, ARNT, ARR3, ARSA, STS, ARSD, ARSE, ARSF, ART1, ASL, ATF3, ATM, ATP6AP1, ATR, AVP, AVPR2, AXL, BACH1, BARD1, BAX, CCND1, BCL2, OPN1SW, BDKRB2, BGLAP, BHMT, BLK, BMI1, BMP1, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, BMX, BRCA1, BRCA2, BTG1, BTK, BUB1, BUB1B, TSPO, C3, C5, CALM3, CAMK4, CAMK2A, CAMK2G, CAV2, CAV3, CBFB, CBL, CBLB, CCIN, CCK, CCNB1, CCNC, CCND3, CCNE1, CCNH, CCNT1, CCNT2, CD4, CD80, CD36, CD40, CD44, CD59, CD74, CDC6, CDC20, CDC25C, CDC27, CDC42, CDK3, CDK4, CDK5, CDK6, CDK8, CDK9, CDKN1A, CDKN2A, CDKN2C, CDKN2D, CENPE, CENPF, CGA, CHAD, CHI3L1, CHRM1, CHRM3, CHUK, CISH, CKS1B, CLU, CLK3, CCR1, CCR5, CNTF, COL3A1, COPA, COPB1, ATF2, CREBL2, CRY1, CRY2, CRYAB, CRYBA1, CSF2, CSF2RB, CSNK1D, CSNK1G2, CSNK1G3, CSNK2A1, CSNK2A2, CSPG4, CTF1, CTGF, CTH, CTSG, CTSZ, CYLD, DAB2, DAD1, CD55, DCN, ACE, DCX, DDB1, DDB2, GADD45A, DHPS, DLG1, DLG2, DLG3, DYNC1H1, DYNC1I1, DYNC1I2, DNMT1, DNMT3B, DPAGT1, DSP, HBEGF, DTX1, DUSP1, DUSP4, DUSP5, DUSP7, DUSP9, DYRK1A, E4F1, GPR183, ECT2, LPAR1, EDN3, EDNRA, EDNRB, PHC1, PHC2, EEF2, EFNA1, EFNA5, EGR2, EHHADH, EIF2S1, EPHA2, EIF5A, ELK1, EMP2, ENSA, EP300, EPB42, EPHA1, EPHA3, EPHA4, EPHA5, EPHA7, EPHA8, EPHB1, EPHB2, EPHB3, ERBB2, EREG, EYA4, ERCC3, ERCC6, ERG, ERN1, ESR1, EXT1, EXT2, EXTL1, EYA1, EYA2, EYA3, EZH1, F2R, F2RL1, F7, F10, ACSL1, FBLN1, EFEMP1, FCER1A, FECH, FGA, FGF1, FGF3, FGF6, FGF7, FGF8, FGF9, FGFR3, FGFR4, FGG, FGR, FKBP3, FKBP5, FLT1, FLT3, FLT3LG, FLT4, FNTA, FPR1, FRK, FSHR, FUT6, FUT8, FYB, FYN, GAD1, GAK, B4GALNT1, GALNT1, GAPDH, GAS6, GATA3, GCG, BLOC1S1, KAT2A, OPN1MW, GDF9, GFI1, GGCX, B4GALT1, GLB1, GMDS, GNAQ, GOLGA2, GOLGB1, SFN, GP1BA, GPLD1, GRK6, GPS2, GPX1, GRB2, RAPGEF1, GRIA1, GRIN2A, GRM1, GUCY2C, GUCY2F, GUCY2D, HIST1H1B, HCK, HCLS1, HGF, NRG1, HHEX, UBE2K, HLCS, HMBS, HMGCR, HPN, HPX, HRC, HRG, PRMT2, PRMT1, HES1, DNAJB2, HSPB1, HSP90AA1, HSP90AB1, HTR2C, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF1R, IGF2, IGFBP3, IL1A, IL1B, IL2RA, IL2RB, IL2RG, IL12RB2, IL13, IL18, ILK, INCENP, INHA, INS, INSRR, IRAK1, IRAK2, ISL1, ITGA1, ITGA2, ITGA5, ITGAV, ITGB1, STT3A, ITPKB, IVL, JARID2, JUN, KCNE1, KDR, KISS1, KIT, KRAS, LIMK1, LIMK2, LIPE, LMAN1, LTF, MAD2L1, SMAD1, SMAD3, SMAD6, SMAD7, MAN2B1, MARK3, MDH2, MAP3K5, MEN1, MGAT2, MGAT5, KITLG, ATXN3, MAP3K11, PPP1R12A, CNOT4, NRAS, NRTN, NTF3, NTRK1, NTRK2, NTRK3, DDR2, NUP88, NUP98, OAS2, TNFRSF11B, P2RX7, P2RY1, P4HA1, PEBP1, PAH, PAM, PARK2, PAWR, PCK1, PCMT1, PCP4, CDK16, PDE4D, PDE6G, PDE6H, PDK4, ENPP1, ENPP2, PDPK1, PER1, PEX12, CFP, PFN2, PGGT1B, PHB, PHEX, PHF2, PHKA2, PHKG1, PIGC, PIK3C3, PIK3CB, PIM1, PIK3CG, PPIB, PPIC, PPID, PPM1A, PPM1B, PPM1G, PPP1CA, PPP1R1A, PPP1R2, PPP1R3C, PPP1R7, PPP2CB, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PPP4C, PPP3R1, PPP5C, PPP6C, PPT1, PRKAA1, PRKAB2, PRKACA, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCA, PRKCB, PRKCE, PRKCG, PRKCI, PRKD1, PRKCQ, PRKCSH, PRKCZ, PRKG1, MAPK3, MAPK8, EIF2AK2, DNAJC3, PRKX, PROC, PROS1, PROX1, RELN, PSKH1, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, PTGER4, PTK7, PTPN1, PTPN3, PTPN4, PTPN6, PTPN7, PTPN12, PTPN13, PTPN14, PTPRA, PTPRB, PTPRD, PTPRE, PTPRH, PTPRJ, PTPRM, PTPRN, PTPRN2, PTPRR, PTPRZ1, RAB1A, RAB3B, RAB6A, RABGGTA, RABGGTB, RAC1, RAC2, RAD51, RAF1, RAG1, RAG2, RANBP2, RAP1A, RAP2A, RAP2B, RARA, RASA2, RB1, ARID4A, RBBP6, RBM4, OPN1LW, REST, RGR, RGS2, RNF2, RNF6, RPN2, RPS3, RPS6KA1, RPS6KA2, RPS6KA3, RPS6KB2, RPS27A, RRAS, RYK, S100A8, S100A9, S100A12, SALL1, SATB1, SBF1, ATXN7, SERPINB3, CCL20, CCL21, CCL22, CCL24, CCL25, XCL1, CX3CL1, SDC4, SDCBP, SEL1L, SET, SETMAR, SFPQ, SGK1, SHC1, SHMT2, SIAH1, SIAH2, ST6GAL1, STIL, SKP1, SKP2, SLAMF1, SLC11A1, SNAI2, SMPD1, SUMO3, SNCA, SNTA1, SOD1, SORL1, SOS1, SOX2, SOX4, SOX9, SP3, SP100, UAP1, SPINK1, SPN, SPRR1B, SPRR2A, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3, SPTA1, SPTB, SREBF1, SRMS, SRPK2, STAT4, AURKA, CDKL5, STK10, STK11, STYX, SUV39H1, XCL2, SYK, TAF5, TAF7, TARBP2, TBL1X, NR2F2, TRAPPC10, TNFAIP3, TNFRSF1A, TNFRSF1B, TOP1, TOP2A, TP73, TPD52L1, TPTE, NR2C2, TRAF2, TRIO, TRPS1, TSC1, TSC2, TSG101, TTC3, TWIST1, TNFRSF4, TYK2, TYRO3, UBB, UBA7, UBE2D1, UBE2D2, UBE2E2, UBE2H, UBE2L3, UBE2V1, UBE2V2, UBE3A, SUMO1, UCN, USP4, KDM6A, UVRAG, VEGFA, VEGFB, VEGFC, EZR, VRK1, VTN, WEE1, WFS1, WHSC1, WNT1, WNT11, WRN, XPC, XRCC4, YWHAG, TRIM25, ZNF207, ZP3, PRDM2, PTP4A1, LRP8, RNF103, FZD5, SCG2, BRPF1, EPM2A, AIMP2, ARHGEF5, TUSC3, NUP214, CUL5, FGF23, USP5, AAAS, CDK2AP1, GAN, AKAP1, SYMPK, USP11, USP9X, KDM5C, SMC1A, UBL4A, KDM5D, USP9Y, HIST1H4I, BAP1, FZD4, FZD7, FZD8, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, BCAR3, DYRK2, CUL4B, CUL4A, CUL3, CUL2, CUL1, TPST2, TPST1, FKBP6, OGT, CDC42BPA, SEMA7A, PPM1D, IKBKG, IKBKAP, HAT1, COPS3, CBX4, CAMK1, MAPKAPK5, CDC14B, CDC14A, MADD, PRKRA, STK16, TNFSF11, USO1, CDK13, PDE5A, DYNLL1, TNKS, EIF3F, PEA15, GALNT4, CDC23, B4GALT4, B4GALT3, B3GALT2, TNK1, URI1, EED, RNGTT, RIPK1, ADAM9, RIPK2, TNFRSF6B, RIOK3, TNFRSF18, TNFRSF10B, TNFRSF10A, DYRK4, TRIM24, CDKL1, DCAF5, IQGAP1, HDAC3, KAT2B, PROZ, CDC16, BCL10, HERC2, CDK5R2, P4HA2, USP13, RPS6KA4, TNFSF18, KALRN, SOCS3, RNF8, BAZ1B, UBA3, DIRAS3, USP14, USP6, USP2, RGN, LATS1, SMC3, CCNE2, DYRK1B, CTDP1, ARHGEF2, ZW10, BUB3, DCLK1, BMP15, AURKB, VAPB, CRLF1, RPS6KA5, STK17B, STK17A, ITGB1BP1, COPB2, GPR55, S1PR2, SOCS6, KLF4, TRIP12, GTF3C4, B4GALT6, B4GALT5, TAOK2, SLIT2, UBE4A, SLC9A3R1, COG1, EIF2AK3, ARHGEF6, PICK1, AKAP6, ATG5, PIGL, PSMF1, GAL3ST1, GDF15, GOSR1, TMEM59, BAG5, BAG4, GMFG, RAB3D, SEC22B, GOSR2, CLOCK, BRE, CDC42BPB, CARTPT, RNF7, TRAF4, AATK, NUP155, TTLL4, DZIP3, KDM4A, NUP93, UBE3C, RAPGEF2, VPRBP, USP34, SETD1A, SLK, HDAC4, RASSF2, DLGAP5, SPOCK2, RNF40, SFI1, CUL7, RB1CC1, DNAJC6, ZEB2, PPP1R26, PSMD6, SETDB1, AREL1, NUAK1, SUPT7L, RNF10, OXSR1, USP3, TNFSF15, NR1H4, RBX1, ABI1, HDAC6, GNE, PIGK, PARP2, PARP3, TOM1L1, SH2D3C, SH2D3A, RANBP9, UBA2, PTPRU, COL4A3BP, CTDSP2, SGK2, RAD50, PREB, FEM1B, FRY, AKAP9, ABI2, TRIM28, RASA4, ATP6AP2, FARP1, CHST4, SORBS3, TNK2, RNF41, PSME3, CTDSPL, TRIB1, STAG1, CWC27, SPEG, TRAIP, BCKDK, MARCH6, TNIP1, B3GNT3, TRIM22, ABCA7, HMG20B, ANAPC10, PIAS3, ST3GAL6, RAPGEF3, SPON1, CD2BP2, UBAC1, ARIH2, SEC24B, RBM14, ZER1, PPIE, MAD2L2, PPIH, COG5, TRIM38, UBE2E3, SEC23A, CRTAP, STK25, CARM1, ATG7, PRDX4, ARL6IP5, SLC35A1, ARFGEF1, ERN2, USP16, TRIM3, HEXIM1, RBCK1, STAMBP, TRIM16, TAF6L, RGS14, CTCF, DCTN6, FUT9, RRH, USP39, NRG3, STAG2, NUP50, ZMYND11, ARPP19, SEC24A, FRS3, SRCAP, RUVBL2, ARID5A, USP19, MALT1, JTB, BRD8, COPS8, PRDX3, KDELR1, OS9, ERP29, RAB40B, TMED10, COPS6, IL24, RBPMS, PIM2, WWP1, WWP2, UBE2C, TMEM115, WDR5, ADAMTS13, ADAMTS5, NUPL2, PTPN21, ATE1, PRDM7, CIT, CDC37, GLMN, WDR45, FICD, STRAP, ADAMTS7, BAZ2A, MAP4K5, RASSF1, CHEK2, FZD10, AKAP13, RNF24, DCTN3, DUSP12, USP18, B4GALT7, LYPLA2, COPE, FKBP9, STK38, PHB2 |
2273 | GO:0045893 | 0.03 | 1.39 | 60.94 | 73 | 151 | positive regulation of transcription, DNA-templated | AGTR2, BRCA2, BRDT, CAMK4, CCNE1, CD80, CD86, CD38, CDH1, CDX2, COL1A1, CREBL2, DAB2, DNM2, ERBB2, ERCC6, F2R, FGF7, HAS3, HMGN1, HNF4G, PRMT2, IFNA2, ILK, ING2, AFF1, PHB, PHF2, PPM1A, PTCH1, RAN, RFXAP, RNF6, RREB1, SMARCA1, SMARCC2, SMARCD3, SNAI1, SRY, TBP, NR2F2, TNNI2, UBTF, WNT11, YWHAH, ZNF711, ZBTB17, ZP3, ZXDA, BRPF1, FGF23, PICALM, FZD7, KLF7, EDF1, TRIM24, BAZ1B, DYRK1B, TRIP4, NR1D1, CREB5, ZNF516, SERTAD2, NR1D2, YAF2, ALYREF, MAD2L2, DEAF1, TRIM16, KLF1, PIM2, SUPT16H, CHEK2 |
2274 | GO:0044271 | 0.00 | 1.39 | 109.36 | 131 | 281 | cellular nitrogen compound biosynthetic process | AARS, ACADM, ACO1, ACP5, ALDH9A1, SLC25A4, ARG1, ARG2, ASL, ASNS, ASS1, ALDH7A1, SLC25A20, CDK4, CIRBP, CPS1, SLC25A10, DARS, DAZ1, DDC, DDX6, DHPS, DIO2, EEF1A2, EEF1B2, EEF2, EIF1AX, EIF2S1, EIF2B1, EIF2S3, EIF4A1, EIF4B, EIF4E, EIF4EBP1, EIF4EBP2, EIF4G1, EIF4G2, EIF5, EIF5A, ELAVL1, EPRS, B4GALNT1, GAPDH, GGT7, GRB7, GSS, HARS, HSPB1, HSP90AA1, HSP90AB1, IGFBP5, EIF3E, IREB2, ITGA2, CAPRIN1, MGST2, OAZ1, OAZ2, ODC1, OTC, P2RX4, P2RX7, PCSK1, PCSK5, PPP1CA, DNAJC3, QARS, QDPR, RBM3, RBM4, RGS2, RPL36AL, RPN2, RPS6KB2, SAT1, SLC25A1, SMPD1, SMPD2, SMS, SRP9, SRP14, SRP19, SRP68, SSR1, SSR3, TARS, TUFM, UGT8, TRPV1, EIF4H, AIMP2, SLC25A16, BBOX1, NSMAF, DENR, PDXK, DDX3Y, EIF3A, EIF3B, EIF3D, EIF3F, EIF3G, EIF3J, CDC123, EIF2B4, EIF2B3, EIF2B2, EIF2B5, EIF2S2, HAP1, SLC25A14, EIF1AY, QKI, GAL3ST1, GTPBP1, EIF5B, PUM1, SPCS2, CTIF, TRAP1, SLC25A15, EIF1, EIF1B, PRG3, ST3GAL6, SLC25A17, EIF3M, SPTLC1, IGF2BP3, FARS2, SEC61B |
2275 | GO:0019953 | 0.00 | 1.38 | 159.48 | 189 | 383 | sexual reproduction | ACOX1, ACVR1, ADCY3, ADCYAP1R1, NR0B1, ANG, ANGPT2, BIRC3, ARNTL, ATM, ATRX, AXL, BAD, BAX, BBS2, BBS4, BCL2, BCL2L1, BIK, PRDM1, BMP4, BRCA2, BRDT, BTG1, CCIN, CCNB1, CD9, CDC25C, CLGN, CFTR, CTSV, CXADR, CYLC1, DAZ1, ACE, DIAPH2, DLD, DNM2, DNMT3A, PHC2, CELSR2, ERCC1, EREG, ETV5, FANCC, FANCD2, FANCG, FSHR, B4GALNT1, GAMT, GATA4, NR6A1, GDF9, B4GALT1, GLRA1, GLRB, HIST1H1T, HIST1H1A, HOXD11, HPGD, AGFG1, IGF1, IGF2R, IHH, IL1B, IL1R1, ING2, INSL3, ITGB1, KIT, LIMK2, LRMP, SMAD1, CD46, SMCP, MEA1, MFGE8, ODF1, ODF2, OR1D2, CLDN11, OVGP1, OVOL1, PAFAH1B2, PAFAH1B3, SERPINA5, CDK16, PDE3A, PGAM2, PGR, PPP2R1A, PRKACA, PRKACG, PRM2, RARA, ARID4A, RGS2, RNF2, RPS6KA2, SBF1, SEPP1, SIAH1, SMARCA2, SMARCA4, SOD1, SOX3, SOX9, SPAG1, SPAG4, SPAM1, SPINK1, SSTR2, SSTR3, STAT3, AURKA, STK11, STYX, T, TAF4B, TARBP2, TBP, NR2F2, TMF1, TNP2, NR2C2, CCT3, TRPC3, TSPY1, TYRO3, UBE3A, ZAN, EIF4H, ZNF35, ZNF148, ZP2, ZP3, DNALI1, FOSL1, AAAS, IFT88, NRIP1, USP9X, USP9Y, TPST2, FKBP6, TP63, PDE5A, DYNLL1, AKAP4, SGPL1, EIF2S2, HERC2, RNF8, RGN, FAM50A, BMP15, QKI, PICK1, ADAMTS2, ADAMTS1, GAL3ST1, TBPL1, CLOCK, SPAG6, PUM1, CEP57, UTP14C, SPATA2, KIAA0196, BCL2L10, BCL2L11, AKAP9, FSTL3, TUBGCP3, CRTAP, DEAF1, PRDX4, CCT7, CCT4, CCT2, CCT6B, CCT8, ADAM28, PRSS21, CCNI, SOX30, HSF2BP, CIT, PTGDR2 |
2276 | GO:0008643 | 0.05 | 1.38 | 49.66 | 59 | 119 | carbohydrate transport | AKT2, AQP1, AQP5, AQP6, AQP7, C3, CREBL2, EDNRA, ESR1, G6PC, SLC37A4, GIP, GPC3, FFAR3, NRG1, HK2, IGF1, IL1B, INS, NUP88, NUP98, ENPP1, PRKAA1, PRKCA, PRKCB, PRKCI, PRKCZ, RANBP2, RAP1A, RTN2, SORT1, SLC2A2, SLC2A3, SLC2A4, SLC2A5, SLC5A2, STXBP3, HNF1A, TSC1, TSC2, VIL1, EZR, NUP214, AAAS, CLTCL1, PIK3R3, PEA15, NUP155, NUP93, C2CD5, SLC23A2, SLC35B1, SLC35A1, SORBS1, NUP50, ARPP19, SLC35D2, NUPL2, CAPN10 |
2277 | GO:0048468 | 0.02 | 1.37 | 71.19 | 85 | 182 | cell development | ACTN1, ACVR1, AKT2, ANGPT2, ATM, BBS2, BCL2L1, BMP1, BMP8B, CASP5, CASP9, SERPINH1, CD9, COL11A1, CRYAB, DIAPH2, DNASE1L3, EDN3, EDNRA, EIF2B1, ELAVL1, ERCC1, ERG, EYA1, FANCC, FANCG, GATA6, HEXB, AGFG1, RBPJ, IL1A, ING2, INHA, INS, ITGA4, KCNJ10, LAMA5, CNOT2, ODF2, PPP2R1B, PRM2, RAB1A, RNF2, RPS19, S100A4, S100A8, S100A9, ST6GAL1, SIX1, SNAI2, SMARCA2, SMARCA4, SOX4, SOX5, TAF4B, TARBP2, TMF1, TRPS1, TYRO3, WNT11, YWHAG, ZP3, EOMES, FZD4, SOX14, ITGA8, ADAM15, ALDH1A2, EIF2B4, EIF2B3, EIF2B2, EIF2B5, RNF8, LATS1, QKI, EIF2AK3, GDF15, TBPL1, SPAG6, CEP57, ZEB2, BCL2L11, TRIM28, DEAF1, FERMT2 |
2278 | GO:0022411 | 0.03 | 1.37 | 61.55 | 73 | 150 | cellular component disassembly | ACTL6A, ADRB2, ANXA5, BNIP3L, TSPO, C5, CA7, CAPS, COX8A, CSNK2A2, EIF2S1, EMD, CTTN, STOM, FANCC, FCGR3B, SLC37A4, BLOC1S1, KAT2A, GOLGA2, HIF1A, HK2, KCNK3, KRT15, MDH1, NTHL1, NUP88, NUP98, PARK2, PGK2, SERPINB10, PRKCA, PRKCB, PRKG1, RANBP2, SFRP4, SLCO1A2, SLC22A3, SNAI2, SNRPD1, SNRPF, SREBF1, STAT2, NR2C2, U2AF1, UBB, VRK1, ZBTB17, ZNF189, FZD5, NUP214, AAAS, CHAF1B, BECN1, BANF1, CCNB2, CHST3, ATG5, NUP155, NUP93, RIMS3, PHYHIP, TOMM20, FGFBP1, TOMM40, ATG7, CSPG5, NUP50, HSF2BP, NUPL2, CDC37, WDR45, ADAMTS7 |
2279 | GO:0005975 | 0.00 | 1.36 | 157.07 | 185 | 380 | carbohydrate metabolic process | ABO, PARP4, ALDH2, ALDH1B1, ALDOB, ALDOC, AREG, ARF4, ART1, ATF3, ATF4, BRS3, CACNA1A, CD44, CD59, CGA, CHI3L1, CLN5, COPA, COPB1, CRY1, CSNK1D, VCAN, CSPG4, SLC25A10, CTSZ, DAD1, CD55, DCN, CYB5R3, DYNC1H1, DYNC1I1, DYNC1I2, DPAGT1, ENO2, EXTL1, GPC4, GPC5, FUT6, FUT8, SLC37A4, GALC, GALE, B4GALNT1, GALNS, GALNT1, GAPDH, GPC3, GM2A, GMDS, GOLGB1, GOT2, GPC1, GRIA1, HEXA, HEXB, ONECUT1, IDH3A, IDS, INPPL1, STT3A, KCNE1, KCNJ11, LDHA, LDHC, LMAN1, LUM, MAN2B1, CHST6, MDH1, MDH2, MGAT2, MGAT5, NUP88, NUP98, OAS1, OAS2, OMD, OGDH, OGN, OVGP1, PCK2, CFP, PGK1, PGK2, PPP2R5D, PPP6C, PRKACA, PRKACB, PRKACG, PRKCSH, RAB1A, RPN2, SDC1, SDC2, SDC4, SEL1L, SGSH, SI, ST6GAL1, SLC2A2, SLC2A3, SLC2A4, SLC2A5, SLC5A2, SLC9A1, SLC25A1, UAP1, SPAM1, SPTA1, SPTB, TRAPPC10, UGDH, UGT2B4, UGT2B7, UGT8, USF1, VEGFB, TUSC3, NUP214, AAAS, PARG, USO1, DYNLL1, TNKS, GALNT4, B4GALT4, B4GALT3, B3GALT2, PAPSS2, PAPSS1, COPB2, B4GALT6, B4GALT5, COG1, GSTO1, CHST3, GAL3ST1, MPDU1, GOSR1, SEC22B, GOSR2, NUP155, HS2ST1, SDC3, NUP93, HS3ST3B1, HS3ST3A1, HS3ST1, SLC23A2, PARP2, PARP3, ABCC5, GPC6, PREB, CHST4, SLC25A13, AKR1A1, ST3GAL6, SPON1, SEC24B, COG5, SEC23A, SLC35A1, DCTN6, CSPG5, FUT9, NUP50, SEC24A, SLC26A1, UGT2A1, KDELR1, OS9, TMED10, SDS, SLC35D2, TMEM115, KERA, ADAMTS13, ADAMTS5, NUPL2, ADAMTS7, DCTN3, B4GALT7, COPE |
2280 | GO:0071702 | 0.01 | 1.36 | 119.21 | 141 | 299 | organic substance transport | ABCA4, ADA, AGXT, ABCD1, APOF, APOH, ARG1, ATP1A2, AVP, BDKRB2, CA1, CA2, CA4, CA5A, CA6, CA7, CACNB4, CCK, CDH17, CHKA, CRY1, CRYM, SLC25A10, CTNS, ACE, DDC, EDN3, EIF4E, SLC29A1, ACSL1, ACSL4, FOLR3, GDF9, GHRH, GHRHR, GIF, GJB1, GLS, GM2A, GOT2, HBA1, HBA2, HHEX, AGFG1, HTR2C, ITGAV, KCNJ10, KISS1, SEPT2, NTRK2, NTSR1, P2RX4, P2RY2, SERPINA5, SLC26A4, ABCD3, RHCE, RHD, S100A8, S100A9, SRSF1, SRSF2, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SLC1A6, SLC1A7, SLC4A1, SLC6A6, SLC6A7, SLC6A8, SLC6A11, SLC6A12, SLC6A13, SLC7A1, SLC7A4, SLC25A1, SYT1, TAF7, SERPINA7, TRPC4, TST, UCN, TRPV1, XK, PAX8, SLC7A5, FZD4, LTBP4, CYP4F2, KHSRP, TNFSF11, SLC4A4, SRSF9, RIPK1, ARHGEF7, SLC5A6, SLC13A2, SLC6A5, SLC22A6, SLC22A8, SLC22A14, SLC22A13, QKI, SLC4A8, DHX38, CKAP5, OSBPL2, SMG7, ABCC5, ATP9A, COL4A3BP, SLC25A13, SLC25A15, ALYREF, DDX39A, ABCC4, SIGMAR1, ABCA10, ABCA9, ABCA8, ATP8A1, SLC25A17, NXF1, UNC13B, ARL6IP5, IGF2BP3, KHDRBS1, SRSF10, SLC26A1, SLC22A7, CFHR4, RNPS1, SERINC3, SLC38A3, SLC27A4, SLC27A2, SLC7A9, CA5B |
2281 | GO:0065007 | 0.00 | 1.36 | 1153.76 | 1259 | 3287 | biological regulation | AAMP, ACLY, ACTL6A, ACVR1, ADAM10, ADK, ADRBK2, AP2A1, AP2B1, AP1G1, AEBP1, AGXT, AHR, ALDH3A1, ALOX15B, ALX3, AMHR2, BIN1, APBB1, APLP1, KLK3, AREG, ARL4D, ARF5, ARG1, RND3, PHOX2A, ARR3, STS, ASCL2, ASIP, ASNA1, ASNS, ASS1, ATF3, ATF4, RERE, ATOH1, BACH1, BAG1, BCHE, BCL2A1, BCL7A, BCL9, OPN1SW, BHMT, BIK, PRDM1, BMP1, BMP8B, BMPR1A, BMX, DST, BPGM, BPI, BRCA1, BRCA2, BRDT, KLF9, KLF5, BTF3, BTG1, C1QA, C1QB, C1QC, C1S, CAPN5, C8B, CACNA2D1, CACNG1, CAMLG, CAPN1, CAPS, CASP4, CASP5, CASP10, RUNX2, RUNX1T1, CBFB, CBL, CBLB, CCNG2, CD3D, CD3G, CD5, CD6, CD8A, CD28, CD80, CD86, TNFRSF8, TNFSF8, CD37, CD53, CD69, CD70, CD72, CD79B, ADGRE5, CD151, CDA, CDC5L, CDH1, CDH6, CDH15, CDH17, CDK3, CDK8, CDX1, CDX2, CDX4, CEBPE, CENPA, CENPB, CHD2, CHD3, CHD4, CHKA, AP2M1, AP1S1, AP2S1, AP3S1, CLC, CLCN2, CLCN5, CLCN7, CLCNKA, CLCNKB, CLK3, CLTA, CLTC, ACKR2, LTB4R, CNN1, CNTF, COL5A1, COL5A2, COL16A1, COL17A1, COMP, CORT, COX8A, CLDN3, CLDN7, CR2, CRX, CRYBA1, CSH1, CSNK1D, CSNK1G2, CSNK1G3, CSNK2A2, CTF1, CTLA4, CTNNA1, CTNND1, CTSV, CUX1, CYP1A2, CYP24A1, DAD1, DAZ1, BRINP1, DCX, DDX1, DDX5, DDX6, DDX11, DFFA, DFNA5, DHCR7, DIAPH2, DLX3, DLX5, DLX6, DMBT1, DNM1, DNMT1, DNMT3A, DNMT3B, DOK1, DPP4, DPYSL3, ARID3A, ATN1, DTNA, DTX1, ECM2, DYRK1A, E2F2, E2F5, E4F1, EBF1, GPR183, EEF2, EFNA3, EFNA4, EFNB2, EGR3, EGR4, EIF2S1, EIF4A1, EIF4B, EIF4E, EIF4EBP1, EIF4G2, EIF5, EIF5A, ELAVL2, ELF1, ELF3, ELK1, ELK3, EMD, EMP3, ADGRE1, EMX2, EN1, EPRS, EPS15, EYA4, ERCC3, ERCC5, ERG, ESRRG, ETS2, ETV1, ETV3, ETV4, ETV6, EVC, EVX1, EWSR1, EXT1, EXT2, EXTL3, EYA1, EYA3, EZH1, FABP6, FABP7, FANCA, ACSL3, ACSL4, EFEMP1, FCGR1B, FCGR2A, FCGR2B, FCGR3B, FCGRT, FCN1, FCN2, GPC4, FGF11, GPC5, FOXD1, FLII, FLT3LG, FLT4, AFF2, FPR2, FPR3, FRK, CENPI, GAST, FUT8, ACKR1, FYB, GABPA, GABRA4, GABRB2, GABRE, GABRG1, GABRR1, GABRR2, GAK, GAMT, GAP43, GAS1, GAS8, NR6A1, OPN1MW, GEM, GFRA1, B4GALT1, GH2, GLRA2, GMDS, GNAZ, GNB2, GNGT1, GNGT2, GNRH2, GNRHR, GPC1, GPD1, GPM6A, GPR1, GPR3, GPR4, GPR15, GPR17, GPR25, GRIA4, GRID1, GRN, GRM8, CXCL2, CXCL3, GRPR, GSC2, GTF3A, BRF1, GUCY2C, GUCY2F, GUCY2D, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H2AE, HIST1H2AD, H2AFZ, HAS1, HAS3, HBA1, HBA2, HDGF, CFHR1, HIC1, HIVEP2, HLA-DQA1, HLF, HLX, HMGN1, HMGA1, NR4A1, HMX1, HMX2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD3, HOXD4, HOXD8, HOXD11, HPGD, HPRT1, HSBP1, DNAJB2, HSPA9, HTR3A, TNC, ICAM2, ICAM4, IDH1, SP110, IFIT3, IFNGR1, IFNW1, IGF2R, IGFBP2, IGFBP6, RBPJ, IL1RAP, IL10RA, IL11RA, IL12RB2, IL15RA, TNFRSF9, IL18, FOXK2, IMPA1, IMPA2, INCENP, IDO1, ING1, ING2, INPP1, INPP4A, INPPL1, INSIG1, INSL3, INSL4, INSRR, EIF3E, IRF5, ISG20, ITGA9, ITGAD, ITGAE, ITGB4, ITGB5, JARID2, JUNB, JUND, CD82, KCNA3, KCNA4, KCNA10, KCNJ3, KCNJ5, KCNJ6, KCNJ9, KCNJ12, KCNJ13, KCNJ14, KCNJ15, KCNJ16, KHK, KLK2, KLRB1, KLRC2, KLRC3, KLRD1, KIF25, KRT4, KRT18, KRT19, KRT84, AFF3, LAMA3, LAMA4, LAMA5, LDHA, ABLIM1, LSP1, LTBP2, BCAM, LUM, CD180, TACSTD2, EPCAM, CAPRIN1, SMAD6, MAL, MAZ, DNAJB9, MDH1, MEIS1, MEOX2, MFGE8, SCGB2A1, CIITA, ATXN3, AFF1, FOXO4, CD200, CITED1, CNOT2, NRF1, NRL, NRTN, NTF4, NTHL1, NTN3, OAS2, ODC1, ODF2, OMD, OGG1, OGN, OMP, OPA1, SIX6, OR1D2, OR1F1, OR2C1, OR3A1, OR3A2, ORC1, ORC2, ORM2, OSBP, OTX1, OTX2, OVGP1, OVOL1, P2RY6, PA2G4, PAEP, PAFAH1B2, PAFAH2, REG3A, PAX1, PDCL, PAX9, PCM1, CHMP1A, PDE4A, PDE7A, PDE8A, PDGFRL, ENPP2, PDYN, PEG3, PENK, PER1, CFP, PFDN1, PFDN2, VIT, PGAM2, PGC, PGF, PGGT1B, PGR, ABCB1, PHF2, PIK3C2B, PIK3C3, PI4KA, PI4KB, PIP4K2A, PRRX1, PPID, PPM1A, PPM1B, PPM1G, PPP2CB, PPP4C, PRCC, PRG2, PRKCSH, PRKX, KLK7, PRSS8, PTBP1, TAS2R38, PTGDR, PTGER1, PTH2R, PTK7, PTPN13, PTPN14, PTPRD, PTPRE, PTPRR, PTPRZ1, RAD1, PURA, PVR, PEX5, RAB6A, RAB13, RAB27B, RAB5C, RALA, RAP2A, RARB, RBBP4, RBBP6, RBBP8, RBM3, RBM4, RBP2, OPN1LW, PRPH2, REG1A, RELB, DPF2, RFX2, RFX4, RFXAP, RGR, RHEB, RLN1, RLBP1, RNASE2, RPL6, RPL24, RPL28, RPL38, RPS3A, RPS4X, RPS6KB2, RPS26, RPS27, RRAS, RREB1, RRM2, RS1, CLIP1, RTN2, RXRG, RYK, S100A4, S100A6, S100A11, SALL1, TSPAN31, SAT1, SATB1, ATXN7, CLEC11A, SCTR, CXCL6, CXCL5, SDC1, SDC2, SDCBP, SEC14L1, SFPQ, SRSF2, SRSF4, SRSF5, SRSF6, SRSF7, SFSWAP, TRA2B, SGTA, SH3BGR, SH3BGRL, SH3BP2, SHB, SHMT2, ST6GAL1, SIX3, SKP2, SLA, SLC5A3, SLC20A1, SLIT3, SNAI2, SMARCA1, SMARCA2, SMARCC1, SMARCC2, SMARCE1, SMPD2, SUMO3, SIGLEC1, SNAI1, SNAPC1, SNAPC2, SNAPC3, SNAPC4, SNRPD1, SON, SOX1, SOX3, SOX5, SOX10, SOX12, SP2, SP4, SPAST, SPIB, SRMS, SRP9, SRPK2, SRY, SSR1, SSRP1, SSTR2, SSTR3, STAC, STAT2, STAT4, STRN, STXBP2, STYX, SULT1A3, SUPT4H1, SUPV3L1, SUV39H1, SVIL, T, TACC1, TAF2, TAF4B, TAF5, TAF13, TARBP1, TBL1X, TBP, ZNF354A, DYNLT3, PRDX2, NR2F1, KLF10, TSPAN7, TMPO, TMPRSS2, CLEC3B, TNNC2, TNFAIP6, TNFRSF1A, TNNI2, TNNT1, TOP1, TOP2A, TPTE, NR2C1, NR2C2, TRHR, TRO, TRPS1, TSN, DNAJC7, TTC3, TTF1, TUFT1, TULP3, TYK2, TYROBP, TYRP1, U2AF1, UBA7, UBE2D2, UBE2E2, UBE2V2, UBE3A, UBTF, UPK1B, UCP1, UNG, KDM6A, VDAC2, VIM, VIPR1, EIF4H, LAT2, CORO2A, WHSC1, WNT2B, XPA, XPC, XRCC2, ZFP37, ZFPL1, ZFX, ZIC1, ZNF3, ZNF711, ZNF7, ZNF8, CNBP, ZNF14, ZNF708, ZNF17, ZNF20, ZNF22, ZNF23, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF80, ZNF84, ZNF221, ZNF90, ZNF91, ZNF124, ZNF132, ZNF133, ZNF134, ZNF136, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, ZNF148, ZBTB17, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, RNF112, ZNF180, ZNF189, ZNF214, ZNF223, ZNF224, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, ZP2, ZXDA, PRDM2, PTP4A1, CSDE1, PXDN, ALMS1, IL1R2, SCG2, BRPF1, EPM2A, AIMP2, FZD3, ZNF212, BRD3, STAM, PDHX, CUL5, USP5, CDK2AP1, MADCAM1, SF3A2, ZNF239, SYMPK, DPF1, CHAF1B, CLTCL1, USP9X, KDM5C, SMC1A, USP9Y, EPX, BAP1, CDC45, EOMES, FZD7, FZD9, HIST1H2AK, HIST2H2AC, OR1A1, OR1E1, OR1E2, OR1G1, OR3A3, SOX14, SPARCL1, SRPX, UXT, ZNF282, UTF1, DYRK2, CUL4B, CUL4A, CUL2, ATRN, TTF2, TPST2, KLF11, FKBP6, SORBS2, IRS4, CDC42BPA, PPM1D, KCNAB2, ITGA8, HAT1, COPS3, CBX4, API5, PIR, FCN3, BLZF1, CDC14A, STK16, OR6A2, KLF7, CDK13, RFXANK, UNC5C, SSNA1, OASL, DCHS1, PTCH2, CHRD, NUMB, DDX3Y, EIF3A, EIF3B, EIF3D, EIF3F, EIF3G, EIF3J, STX10, SRSF9, DNAH11, TNK1, EED, CTNNAL1, HRK, TNFSF12, TNFSF9, TNFRSF6B, TNFRSF18, DLK1, TNFRSF10D, CREG1, IL18RAP, IL1RL2, IL18R1, CDKL1, SAP30, HESX1, NRP2, WISP3, WISP1, HCAR3, TSC22D1, AKAP4, NR1I2, PER3, CDC123, VNN1, AP1S2, AP1M1, PHOX2B, FUBP3, HIST1H2AG, PGLYRP1, TAF1C, TAF1B, TAF1A, RNF8, RHBDL1, TAAR5, UBA3, PSTPIP1, PRC1, ANGPTL1, USP6, PDLIM1, SMC3, CBFA2T2, DYRK1B, CTDP1, IL1RL1, RASSF9, REPS2, DDX21, KCNAB3, DCLK1, ZMYM6, BMP15, CRLF1, GPR50, NUMBL, PDLIM7, STK17B, STK17A, BCL7B, TAAR2, GPR52, ZNF235, NREP, TRIP12, TRIP11, TRIP4, CNOT8, GLP2R, CPNE6, RAB33A, ZFYVE9, CIAO1, RECQL5, ZRANB2, ECEL1, FHL5, IL27RA, THEMIS2, ONECUT2, ADAMTS3, ADAMTS1, LITAF, GDF15, TBPL1, GOSR1, TMEM59, ZNF254, TP53I11, EI24, CIR1, CXCL14, SEC22B, GTPBP1, GOSR2, BRE, CDC42BPB, SOX13, RBM39, CREB5, MAD2L1BP, WTAP, CYTIP, RAB36, FEZ2, ZNF516, SAFB2, EIF5B, SDC3, TTI1, PHF14, KDM4A, VGLL4, BZW1, CEP57, DHX34, ST18, ADAMTSL2, ZNF646, VPRBP, KNTC1, USP34, GPRASP1, CCP110, SETD1A, IFT140, ZNF536, ZFYVE16, KIAA0101, BCLAF1, SNX17, KIAA0586, DLGAP5, SERTAD2, CKAP5, PHYHIP, SPOCK2, RNF40, CTIF, TSC22D2, CUL7, DNAJC6, ZBTB24, ELMO1, GAB2, C2CD5, ZNF518A, KIAA0319, TRIL, SETDB1, AREL1, DDX46, RHOBTB1, SMG7, SNAP91, FIG4, RBM19, FAM20B, RNF10, PAN2, ZBTB5, P2RY14, DLEC1, NR1I3, CLEC2B, FGFBP1, DMTF1, NR2E3, ACOT8, PDCD6IP, FRAT1, PARP2, HMGXB4, RANBP9, AP1M2, ABCC9, IL18BP, PTPRU, GPC6, PQBP1, TSPAN2, TSFM, CTDSP2, PREB, ARL4C, ARL4A, ZNF263, TRAP1, YAF2, ARFRP1, G3BP1, EBI3, CEBPZ, TRIM28, WASF2, ZNF197, SORBS3, ALYREF, CALCRL, NUTF2, EIF1, DDX39A, OLIG2, PRG4, CTDSPL, ZNF443, CD96, STX6, COQ7, LRRC17, STAM2, SF3B4, RAMP3, AKAP8, FSTL3, STAG1, EFS, SIGMAR1, SAP18, EIF1B, SPEG, TRAIP, APC2, KATNB1, APBB3, PCGF3, HMG20A, CITED2, PRG3, IFITM3, SPON2, PGRMC2, ARIH2, TUBGCP3, SEC24B, RBM14, PPIE, GPNMB, SLC30A9, PPIH, UBE2E3, EIF3M, ENOX2, FBLN5, ZNF211, DEAF1, BATF, AGPAT2, SPTLC1, OLFM4, TACC2, SORBS1, IFITM2, MAB21L2, ERN2, USP16, ERLIN1, STAMBP, ARID3B, IVNS1ABP, TRIM16, RASL10A, RAD51AP1, IGF2BP3, DMRT2, KHDRBS1, CXCR6, CGRRF1, CGREF1, CSPG5, EBP, RRH, CNPY3, TBR1, STAG2, SIX2, RBBP9, RAI1, PHTF1, GRAP, CHL1, TRAF3IP2, ZMYND11, SRSF10, ZBTB6, ZNF266, OR5I1, SEPT9, STARD10, ZNF275, SRCAP, ARID5A, CD300C, PROKR1, BRD8, TRAFD1, EDAR, PAPOLA, RNPS1, SEC61B, SERINC3, RAB40B, TMED10, ASCC3, RAB32, CCNI, SLC38A3, CCDC85B, IL24, ATF7, IFT27, RAB35, VAX1, RBPMS, RAB31, STON1, UPK1A, OGFR, ABHD2, WWP1, SOX30, TMEM115, STMN2, TPPP, RER1, ESM1, WDR5, PRDM7, CIT, CD160, ZWINT, IL1RAPL1, GLMN, HHLA2, RABL2B, RABL2A, ERLIN2, SOX21, PSIP1, WDHD1, ADAMTS7, BAZ2A, ZNF277, WDR6, SUPT16H, AKAP11, RASSF8, SEC63, GPR176, NXPH4, NXPH3, GPR45, PTGDR2, SP140, ATXN2L, USP18, TREX1, KLF12, KLF8, B4GALT7, GPR182, ECD, VSIG4, CBX3, GABARAP, SYNPO |
2282 | GO:0006996 | 0.00 | 1.35 | 184.13 | 216 | 455 | organelle organization | ABCA1, ACP2, ACTB, AP2B1, AP1G1, ALAS1, ABCD1, SLC25A4, ARF4, ARL1, ASNA1, RERE, ATP2A1, ATP2B2, CCND1, BLK, BMI1, CACNA1S, CCK, CDK4, CHD1, CHD2, CIRBP, AP2S1, CLU, TPP1, CLN5, CNGA2, DDX1, DDX3X, DDX6, DHX9, DNM1, DYNC1I2, DNM2, TYMP, EMD, EPS15, EYA4, ERCC3, ESR1, ETS1, F2R, FANCG, CENPI, IFI6, GAA, GABPA, GAK, GFER, GOLGB1, GPS2, GRB7, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1T, HIST1H2AE, HIST1H2AD, H2AFZ, H3F3B, HIST1H1A, HEXB, HHEX, HIP1, HMGN1, HMGCL, FOXA2, HPS1, HSPA9, IDUA, ING1, JUN, TNPO1, NRF1, NUP98, OXA1L, ATP8B1, PIK3C2A, PPID, PPP2CB, PPP2R2A, PPT1, SRGN, PRKAB2, PRKACA, PRKAR2B, PTGFRN, PTPRN, PURA, ABCD3, RAB27A, RAB5C, RAG2, RANBP2, RBBP4, RBL1, RBL2, RPL3L, RPL6, RPL10, RPL11, RPL23A, RPL38, RPS19, RPS27, SORT1, SAFB, SCP2, SMARCA1, SMARCA2, SOD2, SOX1, SOX2, SPG7, SRPK2, SSTR3, SUPT4H1, TBP, TOP1, TSPY1, TTF1, TUBA4A, TYRP1, SUMO1, UBTF, WRB, XPC, TUBA1A, BRD3, STAM, AAAS, UBL4A, CDC45, HIST1H2AK, HIST2H2AC, HIST1H2BG, HIST1H2BL, HIST1H2BM, HIST1H2BF, HIST1H2BH, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, SRPX, CUL4A, IKBKAP, COPS3, CBX4, AP3B1, BLZF1, CADPS, TP63, BANF1, SAP30, TMEM11, ARHGEF7, AP1M1, AP3D1, HIST1H3F, HIST1H2AG, HIST1H2BJ, H1FX, TAF1C, TAF1B, TAF1A, AIP, TRIP11, HMGN3, RAB33A, COG1, RECQL4, EIF2AK3, BAG5, CHD1L, NUP155, USP6NL, ZFYVE16, SFI1, RB1CC1, GINS1, ZEB2, SNAP91, FIG4, GOLGA5, RBX1, DOPEY2, ACTR1A, G3BP1, STAM2, SAP18, IKZF1, HMG20B, HMG20A, STK25, ARFGEF2, EXOC5, YME1L1, NUP50, ZMYND11, COPS8, PRDX3, TOMM34, ASCC3, COPS6, RAB32, RAB31, NUPL2, HPS5, SNF8, ATXN2L, CBX3 |
2283 | GO:0034622 | 0.00 | 1.35 | 168.57 | 197 | 406 | cellular macromolecular complex assembly | ADAR, ADD1, ADRB2, AP2B1, ALDOB, BIN1, ANG, ANGPT1, APC, APCS, ARF1, ARF6, ARHGAP6, ARL2, ATM, ATR, BBS4, BICD1, C1QBP, CAPZA1, CAPZB, CASQ2, CAV3, CD36, CIRBP, AP2S1, CLU, CLNS1A, COX15, CRYAB, CSNK1D, CYBA, DDX1, DDX3X, DDX6, DIAPH1, DIAPH2, DLG1, DNAH5, DYNC1H1, EFNA5, EIF2S3, CTTN, EPS8, EPS15, FGA, FGG, GOLGA2, GRB2, GRB7, HCK, HCLS1, NRG1, HIP1, UBE2K, HSPA4, HSP90AA1, ICAM1, INSIG1, EIF3E, KPNB1, TNPO1, IPO5, SMAD1, SMAD3, SMAD6, CNOT2, NUP98, OXA1L, PARK2, PFN1, PFN2, PIK3C2A, PPM1A, PRKCE, EIF2AK2, PSMD4, PSMD5, PSMD8, PSMD11, RAB1A, RAC1, RDX, RGS2, RPL3L, RPL6, RPL10, RPL11, RPL23A, RPL24, RPL38, RPS3, RPS19, RPS27, CLIP1, CCL21, CCL24, SRSF1, SRSF5, SRSF6, SFSWAP, SGK1, SNAP25, SNCA, SNRPC, SNRPD1, SNRPD2, SNRPE, SNRPF, SPAG1, SPTA1, SPTB, SRPK2, STXBP1, SURF1, TARBP2, TAZ, TBCA, TBCD, TMOD1, TRAF2, USP4, UVRAG, VBP1, VDAC2, VIL1, ZNF207, SF3A2, PICALM, PRPF18, DENR, CADPS, EIF3A, EIF3B, EIF3D, EIF3F, EIF3G, EIF3J, SRSF9, SNAP23, SYNJ1, CDC123, WASF1, LATS1, PRPF3, AIFM1, SCAF11, SNAP29, SLIT2, ZFYVE9, PICK1, BAG4, GMFG, PDE4DIP, NUP93, TOMM20, SNAP91, PAN2, HDAC6, RANBP9, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, AKAP9, ABI2, CD2BP2, TUBGCP3, SEC24B, CDC42EP2, BAIAP2, EIF3M, UNC13B, ARPC1A, ARFGEF1, CCT2, CDC42EP3, AVIL, CCT6B, USP39, NRG3, SRSF10, TXNL4A, SF3A3, TMED10, ADRM1, UBE2C, STMN2, TPPP, CDC42EP1, CORO1A, PSIP1, STRAP, ATXN2L, TWF2 |
2284 | GO:0010256 | 0.01 | 1.34 | 136.88 | 160 | 328 | endomembrane system organization | ABCA1, AKT2, ANXA2, AQP1, ARF6, ARL1, ASNA1, ATP1B3, BBS1, BBS2, BCL2L1, BSG, CACNA1S, CALCR, CAV2, CAV3, CCNB1, CDC42, CDH1, AP2M1, CLCN3, CLU, CLTC, COL5A1, CSNK1D, DAB2, DLG1, DNM1, DNM2, DPP6, EPHA2, EMD, EMP2, F2R, ACSL3, FCER1G, FLOT2, FYB, GAK, GAS6, BLOC1S1, GOLGA2, GOLGA4, GOLGB1, AGFG1, IFNG, ITGA3, ITGB1, JUP, KRT18, LAMA5, LMAN1, RAB8A, NUP88, NUP98, P2RX7, P2RY1, CHMP1A, PDPK1, ATP8B1, PIK3C3, PPP2R1A, PPP2R2A, SRGN, PRKCA, PRKCB, PRKCI, PRKD1, PRKCZ, MAPK3, PTCH1, RAB1A, RAB13, RAB27A, RAB5C, RAC1, RANBP2, RAP2A, RDX, CLIP1, S100A9, S100A10, SCP2, SOD1, SPAG4, SPTA1, SPTB, STXBP1, SYP, TMF1, TNFRSF1A, TSC2, TSG101, TULP1, TULP2, TULP3, SUMO1, VIL1, EZR, VRK1, WRB, YWHAZ, NUP214, STAM, AAAS, UBL4A, DYSF, BLZF1, NUMB, VAMP8, STX16, RAB11A, BANF1, LIN7A, SYNJ1, ARHGEF7, AP3D1, MAP7, SYT7, CCNB2, ZW10, VAPB, SLC9A3R1, NRXN1, COG1, EIF2AK3, TBPL1, TMEM59, BAG5, BAG4, NUP155, NUP93, RAPGEF2, USP6NL, IST1, CUL7, GOLGA5, DOPEY2, PDCD6IP, COL4A3BP, ARFRP1, STX6, STAM2, RAMP2, RAMP3, TRDN, ABCA7, BAIAP2, STK25, AGR2, ARFGEF2, ARFGEF1, SORBS1, NUP50, VAMP5, TMED10, RAB31, RER1, NUPL2, SNF8 |
2285 | GO:0006468 | 0.04 | 1.34 | 61.12 | 72 | 154 | protein phosphorylation | ADAM10, ADRBK2, AMHR2, BIRC5, BUB1, BUB1B, CDK3, CDK6, CDK8, CHUK, CCR5, ATF2, CRY1, CRYAB, CSNK2A1, CSNK2A2, CTSG, ELK1, ERCC3, ERG, FYB, GAK, GRK6, GUCY2C, GUCY2F, GUCY2D, ITGAV, LIMK1, LIMK2, LIPE, SMAD1, NRTN, CDK16, PDK4, PHKA2, PHKG1, PIK3C3, PPP2R5D, PRKG1, PSKH1, RARA, RBM4, RPS6KA1, RPS6KA3, RPS6KB2, SKP1, SRPK2, STAT4, NR2C2, TRIO, SCG2, CUL1, CDC42BPA, PRKRA, CDK13, RIOK3, CDKL1, KALRN, DCLK1, STK17A, ARHGEF6, PICK1, CDC42BPB, NUAK1, SH2D3C, SH2D3A, COL4A3BP, SPEG, BCKDK, PRDX4, ERN2, CIT |
2286 | GO:0051252 | 0.00 | 1.34 | 813.37 | 923 | 1949 | regulation of RNA metabolic process | ABCA2, ACTN4, ACTL6A, ACTN1, ACVR1, ACVR1B, ACVR2A, ACVR2B, ACVRL1, ADRB2, AEBP1, AES, AGTR2, NR0B1, AHR, AKT2, ALK, ALX3, ANXA3, ANXA4, APBB1, XIAP, BIRC5, ARF4, RHOH, PHOX2A, ARNT, ARNTL, ASCL2, ATF3, ATF4, RERE, ATOH1, ATRX, BACH1, BARD1, CCND1, BCL3, BCL7A, BCL9, PRDM1, BMI1, BMP1, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, BRCA1, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTG1, BTK, C1QBP, CAMK4, CAMK2A, CAT, RUNX2, RUNX1T1, CBFB, CBL, CCNB1, CCNC, CCNE1, CCNH, CCNT1, CCNT2, CD3D, CD28, CD80, CD86, TNFSF8, CD36, CD38, CD40, CDC5L, CDC6, CDH1, CDK5, CDK8, CDK9, CDKN2A, CDX1, CDX2, CDX4, CEBPE, CEBPG, CENPB, CENPF, CGA, CHD1, CHD2, CHD3, CHD4, CHUK, CLU, CLK3, CMKLR1, COL1A1, ATF2, CREBL2, CRX, CRY1, CRY2, CRYM, CSNK2A1, CSNK2A2, CTH, CTNND1, CTNND2, CUX1, CYLD, DAB2, DGKQ, DCN, DDX1, DDX3X, DDX5, DHFR, DLG1, DLX3, DLX5, DLX6, DNM2, DNMT1, DNMT3A, DNMT3B, ARID3A, ATN1, RCAN1, TSC22D3, DTX1, DYRK1A, E2F2, E2F4, E2F5, E4F1, EBF1, ECM1, EDA, S1PR1, EDNRB, EFNA1, CELSR2, EGR2, EGR3, EGR4, EIF4A2, ELAVL2, ELF1, ELF3, ELK1, ELK3, EMX1, EMX2, EN1, EP300, EPHA5, ERBB2, EREG, EYA4, ERCC3, ERCC6, ERG, ERN1, ESR1, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA1, EYA2, EYA3, EZH1, F2R, F2RL1, FBN1, EFEMP1, FGF1, FGF7, FGF8, FGF9, FGFR3, FOXD1, FLI1, FLII, FLNA, AFF2, FRK, NR5A1, GABPA, GALR1, GAS6, GATA3, GATA4, GATA6, GCG, KAT2A, NR6A1, GDF9, GDNF, GFI1, GPC3, GPS2, ARHGAP35, GSC2, GTF2F1, GTF2I, GTF3A, BRF1, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, H2AFZ, H3F3B, HAS3, HCK, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIF1A, HIP1, HIVEP2, HLF, HLX, HMGN1, HMGA1, NR4A1, HMX1, HMX2, FOXA2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD3, HOXD4, HOXD8, HOXD11, HPN, PRMT2, PRMT1, HES1, HSBP1, HSPA8, ICAM1, IFI16, SP110, IFNA2, IFNG, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL1B, IL10, FOXK2, ILK, ING2, INS, INSIG1, IRAK1, ITGA6, IRAK2, IRF1, IRF2, IRF5, ISL1, ITGA3, JARID2, JUN, JUNB, JUND, JUP, KIT, KRAS, AFF3, ABLIM1, LMO1, LTF, LUM, EPCAM, SMAD1, SMAD3, SMAD6, SMAD7, MAZ, MEIS1, MEN1, MEOX2, CIITA, ATXN3, AFF1, FOXO4, CITED1, PPP1R12A, TONSL, CNOT2, NRF1, NRL, YBX1, NTF3, NTRK1, NTRK3, DDR2, OAS1, OAS3, OGG1, SIX6, ORC1, ORC2, OTX1, OTX2, OVOL1, P2RY1, PA2G4, PCSK6, SERPINE1, PAM, PARK2, PAWR, PAX1, PAX2, PAX9, PBX1, PCK1, CHMP1A, PDE8A, PDPK1, PEG3, PER1, PEX14, PF4, PFDN1, ATP8B1, PFN1, PGR, PHB, PHF2, PIM1, PRRX1, PPID, PPM1A, PPP1R8, PPP2R1A, PPP3R1, PRKAA1, PRKAR1A, PRKCB, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK3, MAPK8, EIF2AK2, PROX1, RELN, PSMA6, PSMC1, PSMC3, PSMC4, PSMC5, PTAFR, PTBP1, PTCH1, PTGIS, PTHLH, PTPN14, PURA, RAF1, RAN, RARA, RARB, RB1, ARID4A, RBBP4, RBBP8, RBL1, RBL2, RBM4, RELB, DPF2, REST, RFC1, RFX2, RFX3, RFX4, RFXAP, RNF2, RNF6, RPL6, RPS3, RPS6KA1, RPS6KA3, RPS26, RPS27A, RREB1, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A12, SAFB, SALL1, SATB1, ATXN7, XCL1, SET, SFPQ, SFRP4, SFRP5, SRSF2, SRSF4, SRSF6, SRSF7, SFSWAP, TRA2B, SGK1, SHH, SIAH2, SIX1, SIX3, SLC9A1, SLC11A1, SNAI2, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCC2, SMARCD3, SMARCE1, SNAI1, SNAPC1, SNAPC2, SNAPC3, SNAPC4, SNCA, SNRNP70, SOD2, SON, SOX1, SOX2, SOX3, SOX4, SOX5, SOX9, SOX10, SOX11, SOX12, SP1, SP2, SP3, SP4, SP100, SPIB, SREBF1, SRF, SRPK2, SRY, SSRP1, STAT2, STAT3, STAT4, STAT5B, SUPT4H1, SUPV3L1, SUV39H1, SYK, T, TAF2, TAF4B, TAF5, TAF6, TAF7, TAF13, TAL1, TARBP1, TARBP2, TBL1X, TBP, HNF1A, ZNF354A, NR2F1, NR2F2, KLF10, NR2E1, TMF1, TMPO, TNFAIP3, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TRPS1, TSC2, TSG101, TTF1, TULP3, TWIST1, TNFSF4, TNFRSF4, TYMS, UBB, UBE2D1, UBE2D2, UBE2L3, UBE2V1, UBE3A, SUMO1, UBTF, UCN, UCP1, SCGB1A1, NR1H2, USF1, USF2, VAV1, VDR, VEGFA, EZR, WFS1, WHSC1, WNT1, WNT2, WNT11, YWHAH, ZFP36, ZFP37, ZFPL1, ZFX, ZIC1, ZIC2, ZNF3, ZNF711, ZNF7, ZNF8, CNBP, ZNF14, ZNF708, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF80, ZNF84, ZNF221, ZNF90, ZNF91, ZNF124, ZNF132, ZNF133, ZNF134, ZNF136, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, TRIM25, ZNF148, ZBTB17, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF180, ZNF189, ZNF207, ZNF214, ZNF223, ZNF224, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, ZP3, ZXDA, PRDM2, LRP8, CSDE1, PAX8, FZD5, BRPF1, MAFK, ARHGEF5, ZNF212, BRD3, CSRP3, FOSL1, FGF23, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, USP9Y, HIST1H4I, PICALM, CDC45, EOMES, FZD4, FZD6, FZD7, FZD8, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NR0B2, UTF1, CUL3, CUL2, FOXN1, TTF2, KLF11, OGT, ITGA8, IKBKG, IKBKAP, HAT1, CBX4, CAMK1, PIR, FCN3, BLZF1, KHSRP, STK16, TNFSF11, KLF7, CDK13, RFXANK, TP63, CHRD, DYNLL1, TNKS, SRSF9, TRADD, EDF1, URI1, EED, RIPK1, RIPK2, CREG1, TRIM24, SAP30, HESX1, CFLAR, HDAC3, TSC22D1, KAT2B, NR1I2, PER3, TAX1BP1, BUD31, CPNE1, BCL10, PHOX2B, FUBP3, HIST1H3F, HIST1H2AG, USP13, RPS6KA4, TNFSF18, TAF1C, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, BTAF1, AIP, USP2, RGN, PDLIM1, RQCD1, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, BMP15, AURKB, CCPG1, RPS6KA5, ITGB1BP1, ZNF235, KLF4, TRIP11, HMGN3, TRIP4, CNOT8, CER1, CIAO1, RECQL5, ZRANB2, HAND1, EIF2AK3, FHL5, HAND2, ONECUT2, LITAF, TBPL1, ZNF254, CIR1, GTPBP1, NR1D1, CLOCK, SOX13, RBM39, CREB5, WTAP, ABCG1, ZNF516, SAFB2, PHF14, KDM4A, VGLL4, BZW1, DHX34, ST18, ZNF646, VPRBP, USP34, SETD1A, ZNF536, HDAC4, ZFYVE16, BCLAF1, SERTAD2, RNF40, TSC22D2, RB1CC1, ZEB2, ZBTB24, ZNF518A, SETDB1, SUPT7L, RNF10, ZBTB5, NR1I3, NR1H4, NR1D2, RBX1, DMTF1, PTBP3, CASP8AP2, NR2E3, SRA1, HDAC6, PQBP1, TSFM, PREB, ZNF263, YAF2, CEBPZ, TRIM28, ZNF197, SORBS3, ALYREF, RNF41, OLIG2, TRIB1, ZNF443, COQ7, DENND4A, SF3B4, IRX5, RAMP3, FSTL3, STAG1, SAP18, APBB3, TNIP1, IKZF1, PCGF3, TRIM22, HMG20B, HMG20A, KLF2, CITED2, PIAS3, IFITM3, RAPGEF3, RBM14, PPIE, MAD2L2, SLC30A9, TRIM38, CREB3, CARM1, ZNF211, DEAF1, BATF, SIVA1, ERN2, USP16, ERLIN1, HEXIM1, RBCK1, ARID3B, TRIM16, TXNIP, TAF6L, RGS14, DMRT2, KHDRBS1, KLF1, CTCF, TBR1, STAG2, SIX2, RAI1, PTTG2, PHTF1, AHCYL1, ZMYND11, SRSF10, ZBTB6, ZNF234, ZNF266, ZNF275, SRCAP, RUVBL2, ARID5A, MALT1, CPSF4, BRD8, PAPOLA, RNPS1, PRDX3, ASCC3, SLC38A3, CCDC85B, ATF7, VAX1, RBPMS, PIM2, WWP1, WWP2, SOX30, WDR5, PRDM7, ERLIN2, SOX21, PSIP1, STRAP, BAZ2A, ZNF277, SUPT16H, CHEK2, SP140, SNF8, KLF12, KLF8, ECD, PHB2, CBX3 |
2287 | GO:0051186 | 0.03 | 1.34 | 79.63 | 93 | 191 | cofactor metabolic process | ACLY, ALAD, ALAS1, ALAS2, ALDOB, ALDOC, AMBP, BLVRA, BLVRB, BPGM, BTD, TSPO, AKR1C4, COX15, CPOX, CYP1A2, DHFR, DLD, SARDH, DNMT1, ENO2, ACSL1, ACSL3, ACSL4, FECH, GAMT, GAPDH, HK2, HLCS, HMBS, HMGCL, HMGCR, HPX, HSD17B4, IDH1, LDHA, MDH1, MDH2, SLC11A2, OGDH, PAH, PCCA, PDK4, PFKFB2, PFKFB4, PGAM2, PGD, PGK1, PGK2, PGM1, PPP2R5D, PPT1, PTGIS, QDPR, RPE, SHMT1, SHMT2, SLC25A1, SNCA, SPTA1, SPTB, STAT3, ELOVL4, TYMS, UROS, SLC25A16, PDHX, OGT, KCNAB2, CYP4F2, PDXK, AKR1C3, DGAT1, SUCLG2, SUCLG1, SUCLA2, GGH, VNN2, VNN1, SLC5A6, KYNU, TP53I3, HDAC4, ACOT8, ABCB6, AASS, COQ7, GLYAT, AHCYL1, ALDH1L1, ACOT2, ECD, ACOT7 |
2288 | GO:0015031 | 0.00 | 1.33 | 269.70 | 313 | 661 | protein transport | ABCA1, ACTN4, ACVR2B, ADAR, ADORA1, AP2A1, AP2B1, AP1G1, ANXA2, ARF4, ARL4D, ARF5, ARF6, RERE, AZGP1, BBS1, BBS2, BBS4, BID, BSG, BTF3, TSPO, VPS51, CALCR, CAMK2G, CBLB, CD3G, SCARB2, CD63, CD74, CENPF, CHI3L1, AP2M1, AP1S1, AP2S1, AP3S1, CLU, CLTA, COL1A1, COPA, COPB1, DMBT1, EGR2, EIF5A, CTTN, EPS15, FAU, FGF9, FYB, GDI2, GFER, GLE1, GOLGA1, GOLGA4, GPM6B, GUK1, HSPA4, HSPA9, HSP90AA1, IFIT1, RBPJ, IL1RN, ITGB1, JUN, KPNB1, KPNA4, KPNA5, TNPO1, KRT18, LAMP2, LTBP2, RPL10A, NUP88, NUP98, OR1D2, CHMP1A, PCSK5, PEX1, PEX6, PEX10, PEX12, PEX14, PPT1, PRKCB, PRKCI, MAPK3, PTCH1, PTPRN, PTPRN2, PEX19, PEX5, RAB1A, RAB3A, RAB3B, RAB4A, RAB6A, RAB13, RAB27A, RAB27B, RABIF, RAB5C, RAF1, RAN, RANBP2, RPGR, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPN2, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, CLIP1, RTN2, S100A12, S100A13, SDCBP, SEL1L, SIX3, SLC11A1, SLC15A1, SLC15A2, SRP9, SRP14, SRP19, SRP68, SSR1, SSR3, STAT3, STXBP2, STXBP3, STYX, TACR2, HNF1A, DYNLT1, TRPS1, TSC2, UFD1L, VIP, YWHAG, YWHAH, YWHAZ, ZP2, ZP3, SCG2, RAB7A, NUP214, STAM, CUBN, AAAS, CLTCL1, AP3B1, BLZF1, USO1, CADPS, SSNA1, AKR1C3, DYNLL1, TNKS, VAMP8, STX16, STX11, STX10, BECN1, SNAP23, LIN7A, AP1S2, AP1M1, HERC2, AP3D1, SELENBP1, HAP1, RPL14, AIP, SEC22C, RABEP1, AP4M1, ARHGEF2, RASSF9, ZW10, COPB2, TRIP11, SNAP29, TAOK2, RPL23, RAB33A, RAB9A, ZFYVE9, COG1, PEX16, EIF2AK3, PICK1, GOSR1, RAB3D, APBA3, SEC22B, VPS26A, GOSR2, RAB36, ABCG1, NUP155, IPO13, NUP93, TRAM2, RIMS2, CEP57, IFT140, ACAP1, ZFYVE16, SNX17, TOMM20, SNAP91, KIAA0196, DOPEY2, HDAC6, PDCD6IP, PDCD6, TOM1L1, TOM1, AP1M2, SCAMP2, KIF20A, PREB, ARFRP1, CALCRL, STX6, AP3S2, STAM2, RAMP2, RAMP3, KATNB1, SEC24B, TOMM40, COG5, SEC23B, SEC23A, APPBP2, ATG7, ARFGEF2, ARFGEF1, TRIM3, TXNIP, EXOC5, TNFSF13B, CCT6B, AP4B1, SIX2, GIPC1, TRAF3IP2, NUP50, AHCYL1, VAMP5, CPLX1, EHD1, KDELR1, AP3M2, SEC61B, TOMM34, RAB40B, TMED10, RAB32, KDELR3, IFT27, RAB35, RAB31, TMEM115, NUPL2, CDC37, AP4S1, RPL35, PRAF2, SEC63, XPOT, SNF8, DDX19B, COPE, PHB2, GABARAP |
2289 | GO:0006974 | 0.01 | 1.33 | 107.11 | 125 | 259 | cellular response to DNA damage stimulus | ACTL6A, PARP4, APBB1, APC, XIAP, BACH1, BARD1, CCNH, CDK3, CDK9, CEBPG, CHD2, CSNK1D, CTLA4, DDB2, DDX1, ERCC1, EYA4, ERCC3, ERCC4, ERCC5, EYA1, EYA2, EYA3, FANCA, FANCC, FANCD2, FANCE, FANCG, FEN1, HMGN1, HMGA1, MEN1, MGMT, ATXN3, NUDT1, TONSL, NTHL1, OGG1, PPP4C, PPP5C, PRKCG, MAPK3, MAPK8, RAD51, RAD51B, RAD51D, RBBP6, REV3L, SETMAR, SFPQ, SGK1, SUMO3, SSRP1, STK11, SUV39H1, TOP2A, UBA7, UBE2E2, UBE2V1, UBE2V2, SUMO1, UFD1L, UNG, UVRAG, WHSC1, WRN, XRCC2, XRCC4, TRIM25, SHFM1, CHAF1B, HIST1H4I, CDC45, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, PARG, IKBKG, COPS3, HERC2, MBD4, RNF8, BAZ1B, SMC3, EXO1, TRIP12, RECQL5, RECQL4, CHD1L, KDM4A, KIAA0101, BCLAF1, NUAK1, DCLRE1A, USP3, PARP2, PARP3, RAD50, TRIM28, ALYREF, DDX39A, CCNO, RBM14, PPIE, VAV3, SLC30A9, RNASEH2A, USP16, RAD51AP1, RUVBL2, COPS8, ASCC3, COPS6, PAPD7, RASSF1, SUPT16H, TP53TG1, TREX1 |
2290 | GO:0000209 | 0.05 | 1.33 | 64.27 | 75 | 154 | protein polyubiquitination | XIAP, BARD1, BCL2, BRCA1, CBFB, CDC27, CDKN2A, DDB2, UBE2K, PARK2, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RNF6, RPS27A, SKP2, TNFAIP3, TRAF2, TTC3, UBB, UBE2D1, UBE2D2, UBE2E2, UBE2H, UBE2L3, UBE2V1, UBE2V2, UBE3A, CUL3, TNKS, CDC23, CDC16, RNF8, TRIP12, UBE4A, PSMF1, DZIP3, UBE3C, RNF40, PSMD6, HDAC6, RNF41, PSME3, MARCH6, ANAPC10, ARIH2, TRIM38, UBE2E3, RBCK1, WWP2, UBE2C, RNF24 |
2291 | GO:1903506 | 0.00 | 1.33 | 784.16 | 889 | 1879 | regulation of nucleic acid-templated transcription | ABCA2, ACTN4, ACTL6A, ACTN1, ACVR1, ACVR1B, ACVR2A, ACVR2B, ACVRL1, ADRB2, AEBP1, AES, AGTR2, NR0B1, AHR, AKT2, ALK, ALX3, ANXA3, ANXA4, APBB1, XIAP, BIRC5, ARF4, RHOH, PHOX2A, ARNT, ARNTL, ASCL2, ATF3, ATF4, RERE, ATOH1, ATRX, BACH1, CCND1, BCL3, BCL7A, BCL9, PRDM1, BMI1, BMP1, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, BRCA1, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTG1, BTK, C1QBP, CAMK4, CAMK2A, CAT, RUNX2, RUNX1T1, CBFB, CBL, CCNC, CCNE1, CCNH, CCNT1, CCNT2, CD3D, CD28, CD80, CD86, TNFSF8, CD36, CD38, CD40, CDC5L, CDC6, CDH1, CDK5, CDK8, CDK9, CDKN2A, CDX1, CDX2, CDX4, CEBPE, CEBPG, CENPB, CENPF, CGA, CHD1, CHD2, CHD3, CHD4, CHUK, CLU, CMKLR1, COL1A1, ATF2, CREBL2, CRX, CRY1, CRY2, CRYM, CSNK2A1, CSNK2A2, CTH, CTNND1, CTNND2, CUX1, CYLD, DAB2, DGKQ, DCN, DDX1, DDX3X, DDX5, DHFR, DLG1, DLX3, DLX5, DLX6, DNM2, DNMT1, DNMT3A, DNMT3B, ARID3A, ATN1, RCAN1, TSC22D3, DTX1, E2F2, E2F4, E2F5, E4F1, EBF1, ECM1, EDA, S1PR1, EDNRB, EFNA1, CELSR2, EGR2, EGR3, EGR4, EIF4A2, ELAVL2, ELF1, ELF3, ELK1, ELK3, EMX1, EMX2, EN1, EP300, EPHA5, ERBB2, EREG, EYA4, ERCC3, ERCC6, ERG, ERN1, ESR1, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA1, EYA2, EYA3, EZH1, F2R, F2RL1, FBN1, EFEMP1, FGF1, FGF7, FGF8, FGF9, FGFR3, FOXD1, FLI1, FLII, FLNA, FRK, NR5A1, GABPA, GALR1, GAS6, GATA3, GATA4, GATA6, GCG, KAT2A, NR6A1, GDF9, GDNF, GFI1, GPC3, GPS2, ARHGAP35, GSC2, GTF2F1, GTF2I, GTF3A, BRF1, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, H2AFZ, H3F3B, HAS3, HCK, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIF1A, HIP1, HIVEP2, HLF, HLX, HMGN1, HMGA1, NR4A1, HMX1, HMX2, FOXA2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD3, HOXD4, HOXD8, HOXD11, PRMT2, PRMT1, HES1, HSBP1, HSPA8, ICAM1, IFI16, SP110, IFNA2, IFNG, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL1B, IL10, FOXK2, ILK, ING2, INS, INSIG1, IRAK1, ITGA6, IRAK2, IRF1, IRF2, IRF5, ISL1, ITGA3, JARID2, JUN, JUNB, JUND, JUP, KIT, KRAS, AFF3, ABLIM1, LMO1, LTF, LUM, EPCAM, SMAD1, SMAD3, SMAD6, SMAD7, MAZ, MEIS1, MEN1, MEOX2, CIITA, ATXN3, AFF1, FOXO4, CITED1, PPP1R12A, TONSL, CNOT2, NRF1, NRL, YBX1, NTF3, NTRK1, NTRK3, DDR2, OGG1, SIX6, ORC1, ORC2, OTX1, OTX2, OVOL1, P2RY1, PA2G4, PCSK6, SERPINE1, PAM, PARK2, PAWR, PAX1, PAX2, PAX9, PBX1, PCK1, CHMP1A, PDE8A, PDPK1, PEG3, PER1, PEX14, PF4, PFDN1, ATP8B1, PFN1, PGR, PHB, PHF2, PIM1, PRRX1, PPID, PPM1A, PPP1R8, PPP2R1A, PPP3R1, PRKAA1, PRKAR1A, PRKCB, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK3, MAPK8, EIF2AK2, PROX1, RELN, PSMA6, PSMC1, PSMC3, PSMC4, PSMC5, PTAFR, PTCH1, PTGIS, PTHLH, PTPN14, PURA, RAF1, RAN, RARA, RARB, RB1, ARID4A, RBBP4, RBBP8, RBL1, RBL2, RELB, DPF2, REST, RFC1, RFX2, RFX3, RFX4, RFXAP, RNF2, RNF6, RPL6, RPS3, RPS6KA1, RPS6KA3, RPS27A, RREB1, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A12, SAFB, SALL1, SATB1, ATXN7, XCL1, SET, SFPQ, SFRP4, SFRP5, SRSF2, SFSWAP, SGK1, SHH, SIAH2, SIX1, SIX3, SLC9A1, SLC11A1, SNAI2, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCC2, SMARCD3, SMARCE1, SNAI1, SNAPC1, SNAPC2, SNAPC3, SNAPC4, SNCA, SOD2, SOX1, SOX2, SOX3, SOX4, SOX5, SOX9, SOX10, SOX11, SOX12, SP1, SP2, SP3, SP4, SP100, SPIB, SREBF1, SRF, SRY, SSRP1, STAT2, STAT3, STAT4, STAT5B, SUPT4H1, SUV39H1, SYK, T, TAF2, TAF4B, TAF5, TAF6, TAF7, TAF13, TAL1, TARBP1, TBL1X, TBP, HNF1A, ZNF354A, NR2F1, NR2F2, KLF10, NR2E1, TMF1, TMPO, TNFAIP3, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TRPS1, TSC2, TSG101, TTF1, TULP3, TWIST1, TNFSF4, TNFRSF4, TYMS, UBB, UBE2D1, UBE2D2, UBE2L3, UBE2V1, UBE3A, SUMO1, UBTF, UCN, UCP1, SCGB1A1, NR1H2, USF1, USF2, VAV1, VDR, VEGFA, EZR, WFS1, WHSC1, WNT1, WNT2, WNT11, YWHAH, ZFP36, ZFP37, ZFPL1, ZFX, ZIC1, ZIC2, ZNF3, ZNF711, ZNF7, ZNF8, CNBP, ZNF14, ZNF708, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF80, ZNF84, ZNF221, ZNF90, ZNF91, ZNF124, ZNF132, ZNF133, ZNF134, ZNF136, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, TRIM25, ZNF148, ZBTB17, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF180, ZNF189, ZNF207, ZNF214, ZNF223, ZNF224, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, ZP3, ZXDA, PRDM2, LRP8, CSDE1, PAX8, FZD5, BRPF1, MAFK, ARHGEF5, ZNF212, BRD3, CSRP3, FOSL1, FGF23, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, USP9Y, HIST1H4I, PICALM, CDC45, EOMES, FZD4, FZD6, FZD7, FZD8, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NR0B2, UTF1, CUL3, CUL2, FOXN1, TTF2, KLF11, OGT, ITGA8, IKBKG, IKBKAP, HAT1, CBX4, CAMK1, PIR, BLZF1, KHSRP, STK16, TNFSF11, KLF7, CDK13, RFXANK, TP63, CHRD, DYNLL1, TNKS, TRADD, EDF1, URI1, EED, RIPK1, RIPK2, CREG1, TRIM24, SAP30, HESX1, CFLAR, HDAC3, TSC22D1, KAT2B, NR1I2, PER3, TAX1BP1, BUD31, CPNE1, BCL10, PHOX2B, FUBP3, HIST1H3F, HIST1H2AG, USP13, RPS6KA4, TNFSF18, TAF1C, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, BTAF1, AIP, USP2, PDLIM1, RQCD1, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, BMP15, AURKB, CCPG1, RPS6KA5, ITGB1BP1, ZNF235, KLF4, TRIP11, HMGN3, TRIP4, CNOT8, CER1, CIAO1, RECQL5, ZRANB2, HAND1, EIF2AK3, FHL5, HAND2, ONECUT2, LITAF, TBPL1, ZNF254, CIR1, NR1D1, CLOCK, SOX13, RBM39, CREB5, ABCG1, ZNF516, SAFB2, PHF14, KDM4A, VGLL4, BZW1, ST18, ZNF646, VPRBP, USP34, SETD1A, ZNF536, HDAC4, ZFYVE16, BCLAF1, SERTAD2, TSC22D2, RB1CC1, ZEB2, ZBTB24, ZNF518A, SETDB1, SUPT7L, RNF10, ZBTB5, NR1I3, NR1H4, NR1D2, RBX1, DMTF1, CASP8AP2, NR2E3, SRA1, HDAC6, PQBP1, TSFM, PREB, ZNF263, YAF2, CEBPZ, TRIM28, ZNF197, SORBS3, ALYREF, RNF41, OLIG2, TRIB1, ZNF443, COQ7, DENND4A, IRX5, RAMP3, FSTL3, STAG1, SAP18, APBB3, TNIP1, IKZF1, PCGF3, TRIM22, HMG20B, HMG20A, KLF2, CITED2, PIAS3, RAPGEF3, RBM14, PPIE, MAD2L2, SLC30A9, TRIM38, CREB3, CARM1, ZNF211, DEAF1, BATF, SIVA1, ERN2, USP16, ERLIN1, HEXIM1, RBCK1, ARID3B, TRIM16, TXNIP, TAF6L, RGS14, DMRT2, KHDRBS1, KLF1, CTCF, TBR1, STAG2, SIX2, RAI1, PTTG2, PHTF1, ZMYND11, SRSF10, ZBTB6, ZNF234, ZNF266, ZNF275, SRCAP, RUVBL2, ARID5A, MALT1, BRD8, PRDX3, ASCC3, SLC38A3, CCDC85B, ATF7, VAX1, RBPMS, PIM2, WWP1, WWP2, SOX30, WDR5, PRDM7, ERLIN2, SOX21, PSIP1, STRAP, BAZ2A, ZNF277, SUPT16H, CHEK2, SP140, SNF8, KLF12, KLF8, ECD, PHB2, CBX3 |
2292 | GO:1901137 | 0.01 | 1.33 | 131.40 | 153 | 318 | carbohydrate derivative biosynthetic process | ABO, PARP4, AP2A1, ANGPT1, AREG, ARF4, ART1, BCL2, BMPR2, CD59, CGA, CLTC, COPA, COPB1, CSNK1D, VCAN, CSPG4, CTSZ, DAD1, CD55, DCN, DYNC1H1, DYNC1I1, DYNC1I2, DPAGT1, HBEGF, EXT1, EXT2, EXTL1, EXTL2, EXTL3, GPC4, GPC5, FUT6, FUT8, B4GALNT1, GALNT1, B4GALT1, GK, GK2, GPC3, GLB1, GMDS, GOLGA2, GOLGB1, GPC1, GRIA1, HAS1, HAS2, HAS3, HEXA, IGF1, IL1B, INS, STT3A, KCNE1, LMAN1, LUM, CHST6, MGAT2, MGAT5, OAS2, OMD, OGN, PAWR, CFP, PIGC, PPP6C, PRKAA1, PRKCSH, RAB1A, RPN2, CCL21, SDC1, SDC2, SDC4, SEL1L, ST6GAL1, SLC2A4, SORD, UAP1, SPTA1, SPTB, TRAPPC10, UGDH, UGP2, UGT8, VEGFB, TUSC3, OGT, USO1, DYNLL1, TNKS, GALNT4, B4GALT4, B4GALT3, B3GALT2, KAT2B, COPB2, B4GALT6, B4GALT5, COG1, CHST3, PIGL, GAL3ST1, MPDU1, GOSR1, TMEM59, SEC22B, GOSR2, HS2ST1, SDC3, PTDSS1, XYLB, HS3ST3B1, HS3ST3A1, HS3ST1, ACOT8, GNE, PIGK, PARP2, PARP3, ABCC5, GPC6, PREB, CHST4, TNIP1, AKR1A1, B3GNT3, ABCA7, ST3GAL6, SPON1, SEC24B, COG5, SEC23A, SLC35A1, ARFGEF1, DCTN6, CSPG5, FUT9, SEC24A, KDELR1, OS9, TMED10, SLC35D2, TMEM115, KERA, ADAMTS13, ADAMTS5, ADAMTS7, DCTN3, B4GALT7, COPE |
2293 | GO:0048522 | 0.04 | 1.33 | 63.46 | 75 | 176 | positive regulation of cellular process | ARHGAP6, ATP1B3, BST2, CA7, CASP10, CD8A, CHN1, CHN2, CHRNB4, COL3A1, CSNK1G2, CTSS, DBI, DNM1, DPP6, EPS8, EVC, FOXD1, GJA5, FFAR3, HIC1, IGFBP5, ITPR3, KCNE1, KCNJ2, KCNJ11, KCNQ1, CD180, ATXN3, KLK6, RAB3B, RFNG, S100A1, S100A4, SH3BGR, SH3BGRL, SH3BP2, SHB, SLA, SLC8A3, SLC12A1, SLC34A1, SLC20A1, SNAP25, SORL1, STC1, TNR, NR2C1, WNT2B, SLC30A2, SHOC2, IFT88, IRS4, PIK3R3, CNTNAP1, USP13, DGKI, AKAP7, ADAMTS3, LITAF, PUM1, USP34, KCNE3, SH2B3, FRAT1, SH2D3C, SH2D3A, ATP6AP2, AGPAT2, SH2B2, HEXIM1, GRAP, TRAF3IP2, STARD10, PTGDR2 |
2294 | GO:1902589 | 0.00 | 1.32 | 476.04 | 545 | 1151 | single-organism organelle organization | ABL2, ACTG1, ACTN4, ACTN1, ADCY3, ADD1, ADRB2, AKT2, ANG, ANXA1, ANXA2, ANXA5, APC, BIRC5, APOA1, SHROOM2, AQP1, AREG, ARF1, ARF6, RND3, ARHGAP6, ARHGDIB, ARL2, BAD, BAX, BBS1, BBS2, BBS4, BCL2, BCL2A1, BCL2L1, BICD1, BID, BMP4, BNIP3, BNIP3L, BRDT, BST2, BUB1, BUB1B, TSPO, C1QBP, C5, CA7, CAMK2A, CAPS, CAPZA1, CAPZB, CASP8, CASQ2, CAV2, CAV3, CCNG2, CD28, CD59, CDC6, CDC20, CDC25C, CDC27, CDC42, CDK3, CDK5, CDKN2A, CENPA, CENPE, CENPF, CETN1, CFL2, CHD3, CHD4, CLCN3, CLTC, CNN1, CNN3, CNP, COPA, COPB1, COX8A, CRYAB, CSNK1D, CSNK2A1, CSNK2A2, CTGF, CTNNA1, CTSK, CTSV, CTSZ, CXADR, CYLD, DBN1, GADD45A, DDX11, DFFB, DIAPH1, DIAPH2, DLG1, DNAH5, DYNC1H1, DNMT3A, DPYSL3, DUSP1, E2F4, E4F1, ECT2, S1PR1, LPAR1, EDN3, EFNA5, CELSR2, EIF2S1, EML1, EMP2, CTTN, ENSA, EPB41, EPB41L2, STOM, EPHA1, EPHA3, EPHA5, EPS8, EREG, F2RL1, FANCA, FANCC, FANCD2, FCGR3B, FGD1, FGF7, FGF8, FGFR3, FLII, FLNA, SLC37A4, GAPDH, BLOC1S1, GEM, GHSR, GNAI3, GOLGA2, SFN, GPM6B, GPR3, GRB2, GRIA1, CXCL1, HSD17B10, HARS, HCK, HCLS1, HGF, HIF1A, HK2, HMGA1, ONECUT1, HRG, HSPA4, HSP90AA1, ICAM1, IGF1, IGF1R, IGF2, IL1A, ILK, INCENP, ING2, INS, INPPL1, INSIG1, INSRR, ITGB1, ITGB5, JUP, KCNK3, KIT, KLC1, KIF25, KPNB1, KRAS, KRT15, KRT19, LAMA5, ABLIM1, LIMK1, LLGL2, LMAN1, LRMP, TACSTD2, MAD2L1, SMAD3, MAP6, MDH1, RAB8A, MKI67, MYO1B, PPP1R12A, NUBP1, SEPT2, NTF3, NTHL1, NTRK3, NUMA1, NUP88, OCRL, ODF2, OPA1, OPHN1, PAM, PARK2, PAWR, PCM1, CHMP1A, PDE3A, PDPK1, PEX1, PEX6, PEX10, PEX12, PEX14, PFN1, PFN2, PGK2, SERPINB10, PIK3C3, PPP2R1A, PPP3R1, PPP6C, PRKAR1A, PRKCE, PRKCI, PRKCZ, PRKG1, PRM2, PROX1, PTGER4, PTK7, PTPN1, RAD1, PEX19, PEX5, RAB1A, RAB3A, RAB13, RAC1, RAC2, RAC3, RAD51B, RALA, RAN, RAP2A, RB1, RBBP8, RDX, RFX3, RFX4, RGS2, RPGR, RPL24, RPL28, RPS3, RPS6KA2, RPS27A, CLIP1, S100A9, S100A10, CCL21, CCL24, SDC4, SDCBP, SFRP4, SGK1, SHC1, STIL, SLAMF1, SLC9A1, SLC16A1, SLCO1A2, SLC22A3, SMARCA4, SMARCC1, SMARCC2, SMARCD3, SMARCE1, SNAP25, SNRPD1, SNRPF, SON, SPAG1, SPAG4, SPAST, SPTA1, SPTB, SRF, STAT2, STAT3, STXBP1, SUPV3L1, SYP, SYT1, SYT4, TAC1, TACC1, CNTN2, TAZ, TBCD, TBCE, DYNLT3, DYNLT1, TRAPPC10, TMF1, TMOD1, TNNT2, TOP2A, NR2C2, TSC1, TSG101, TUFM, U2AF1, UBB, UBE2D1, CLRN1, UVRAG, VIL1, EZR, CORO2A, WEE1, WNT11, XRCC2, YWHAG, YWHAH, YWHAZ, ZIC2, ZBTB17, ZNF189, ZNF207, ALMS1, FZD5, RAB7A, ARHGEF5, NUP214, CSRP3, IFT88, CHAF1B, CLTCL1, USP9X, SMC1A, DYSF, PICALM, UXT, EEA1, CUL3, FKBP6, SORBS2, CDC42BPA, OFD1, CDC14A, DENR, USO1, CDK13, SSNA1, DYNLL1, VAMP8, STX16, STX11, STX10, BECN1, CDC23, RAB11A, SNAP23, CFLAR, AKAP4, CDC16, WASF1, HAP1, MAP7, PRC1, LATS1, ATP6V0D1, SEC22C, SMC3, AIFM1, CCNB2, CTDP1, ARHGEF2, ZW10, BUB3, VAPB, VAPA, PDLIM7, CYTH2, ITGB1BP1, COPB2, S1PR2, TRIP10, SNAP29, TAOK2, SLIT2, SLC9A3R1, KIF3B, NRXN1, NRXN2, RECQL5, PEX16, CRIPT, PICK1, CHST3, ONECUT2, TBPL1, GOSR1, BAG4, GMFG, SEC22B, BCAR1, GOSR2, BRE, CDC42BPB, MAD2L1BP, IQCB1, CEP135, NUP93, KIAA0391, CROCC, CEP57, RUBCN, SEMA3E, KNTC1, CCP110, IFT140, SLK, KIAA0101, RIMS3, KIAA0586, DLGAP5, CKAP5, PHYHIP, IST1, TOMM20, CUL7, ARHGEF17, ELMO1, C2CD5, KIAA0753, FARP2, KIAA0196, WDR1, FGFBP1, ABI1, PDCD6IP, BCL2L11, TOM1L1, RANBP9, SMC4, COL4A3BP, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSFM, ARPC2, KIF20A, PREB, FRY, AKAP9, ABI2, WASF2, SORBS3, STX6, COQ7, ABCC4, AKAP8, STAG1, APC2, KATNB1, CCNO, TRDN, TUBA1B, CORO2B, ANAPC10, ATP8A1, RAPGEF3, TUBGCP3, SEC24B, CDC42EP2, ACAA2, VAV3, TOMM40, BAIAP2, MAD2L2, TACC3, SEC23A, CAP1, SSSCA1, ARPC1A, ARFGEF1, SIVA1, TACC2, SORBS1, ERN2, CDC42EP3, GAS2L1, RGS14, DCTN6, CSPG5, AVIL, STAG3, STAG2, PTTG2, ARPP19, VAMP5, SEPT9, SEC24A, JTB, TXNL4A, EHD1, TMED10, IFT27, PIM2, PAPD7, UBE2C, STMN2, TPPP, HSF2BP, CIT, KIF3A, ZWINT, CAPN10, KPTN, CDC42EP1, CDC37, CORO1A, WDR45, WDHD1, ADAMTS7, SUPT16H, CHEK2, FZD10, DCTN3, COPE, PHB2, GABARAP, OIP5, TWF2, SYNPO |
2295 | GO:0035556 | 0.02 | 1.31 | 96.25 | 112 | 244 | intracellular signal transduction | AGTR2, AKT2, ATF4, ATP2A1, AVPR2, BAG1, BCL2A1, BLK, BMX, BNIP3, BTK, CAMK4, CAPS, CASP4, CBLB, CD14, CD80, CD86, CSH1, DGKA, DGKB, DGKQ, DCX, EIF4EBP1, EIF4EBP2, FYB, GH2, GNAZ, CXCL1, GUCY2C, GUCY2F, GUCY2D, UBE2K, NR4A1, ITPR3, SMAD3, SMAD6, SMAD7, FOXO4, PAX2, PDCL, PIK3C2A, PIK3C2B, PI4KA, PI4KB, PPP1R1A, PPP3R1, PRKACB, PRKACG, PRKAR1A, PRKAR2A, PRKAR2B, PRKCG, PRKCI, PRKCSH, PTAFR, RPS6, RPS6KB2, RYR1, RYR3, S100A1, SGK1, SHH, SMPD2, SRPK2, STAC, STAT2, STAT3, STAT4, STAT5B, STK10, TUFT1, TYK2, TYRO3, TYROBP, LAT2, CORO2A, XPA, CUL5, ANP32A, NSMAF, CUL4A, CUL2, CDC42BPA, DGKE, DCHS1, DYNLL1, ADAM15, RGS11, RGS9, RPS6KA4, LATS1, AIFM1, DCLK1, STK17B, STK17A, ECEL1, AKAP7, CDC42BPB, SLK, GAB2, NUAK1, OXSR1, SH2B3, SGK2, EFS, TRAIP, UNC13B, PRDX4, SIVA1, NRG3, GPR182 |
2296 | GO:0006725 | 0.00 | 1.30 | 1063.60 | 1181 | 2621 | cellular aromatic compound metabolic process | AARS, ABAT, ABCA2, ACHE, ACTN4, ACTL6A, ACTN1, ACVR1, ACVR1B, ACVR2A, ACVR2B, ACVRL1, ADAR, ADARB1, PARP4, AEBP1, AES, AGTR2, NR0B1, AHR, AKT2, ALAD, ALAS1, ALAS2, ALK, ALX3, ANG, ANPEP, ANXA1, ANXA3, ANXA4, AOC2, APBB1, XIAP, BIRC5, AREG, ARF4, RHOH, PHOX2A, ARNTL, ASCL2, ASIP, ATF3, ATF4, RERE, ATOH1, ATR, ATRX, AZGP1, BACH1, BARD1, BCHE, CCND1, BCL2, BCL3, BCL7A, BCL9, BICD1, PRDM1, BMI1, BMP1, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, BRCA1, BRCA2, BRDT, KLF9, KLF5, BTF3, BTG1, BTK, BYSL, C1QBP, CAMK4, CAMK2A, RUNX2, RUNX1T1, CBFB, CBL, CBS, CCNB1, CCNC, CCNE1, CCNH, CCNT1, CCNT2, CD3D, CD28, CD80, CD86, TNFSF8, CD36, CD38, CD40, CDC5L, CDC6, CDC25C, CDC42, CDH1, CDH3, CDK5, CDK8, CDK9, CDKN1A, CDKN2D, CDX1, CDX2, CDX4, CEBPE, CEBPG, CENPB, CENPF, CGA, CHD1, CHD2, CHD3, CHD4, CHRNB2, CHUK, CLU, CLK3, CLNS1A, CMKLR1, COL1A1, COX5B, COX6A1, COX6B1, COX7B, COX7C, CPOX, CPS1, ATF2, CREBL2, CRX, CRY1, CRY2, CRYM, CSF2, CSNK1D, CSNK2A1, CSNK2A2, CSTF3, CTGF, CTH, CTNND1, CTNND2, CUX1, CYLD, CYP1A2, CYP2F1, DAB2, DGKQ, DAO, DARS, DCN, DDB1, DDB2, DDC, GADD45A, DDX1, DDX3X, DDX5, DHX8, DHX9, DDX10, DDX11, DHODH, DIO1, DIO2, DLX3, DLX5, DLX6, DNM2, TRDMT1, DNTT, DPAGT1, ARID3A, ATN1, RCAN1, TSC22D3, DTX1, DTYMK, DUSP1, DYRK1A, E2F2, E2F4, E2F5, E4F1, EBF1, ECM1, EDA, S1PR1, EFNA1, CELSR2, EGR2, EGR3, EGR4, ELAVL2, ELF1, ELF3, ELK1, ELK3, EMX1, EMX2, EN1, SLC29A1, EP300, EPHA5, EPRS, ERBB2, ERCC1, EREG, EYA4, ERCC3, ERCC4, ERCC5, ERCC6, ERG, ESR1, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EXTL2, EYA1, EYA2, EYA3, EZH1, F2R, F2RL1, FANCA, FANCC, FANCD2, FANCE, FANCG, FBN1, EFEMP1, FECH, FGF1, FGF7, FGF8, FGF9, FGFR3, FGFR4, FOXD1, FLI1, FLII, FLNA, AFF2, FRK, NR5A1, FUT8, GABPA, GARS, GAS6, GATA3, GATA4, GATA6, KAT2A, NR6A1, GDF9, GDNF, GFI1, GIF, GPC3, GLS, GMDS, GOT2, SFN, GPS2, GPX2, GRIN2A, ARHGAP35, GRSF1, GSC2, GSTM1, GSTM2, GTF2F1, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, H2AFZ, H3F3B, HSD17B10, HARS, HAS3, HCK, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIP1, HIVEP2, HLF, HLX, HMBS, HMGN1, HMGA1, NR4A1, HMX1, HMX2, FOXA2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD3, HOXD4, HOXD8, HOXD11, HPN, HPX, PRMT2, PRMT1, HES1, HSBP1, ICAM1, IDH1, IFI16, SP110, IFNA2, IFNG, IGF1R, IGF2, RBPJ, IHH, IL1A, IL10, FOXK2, ILK, ING2, INSIG1, IRAK1, ITGA6, IRAK2, IRF1, IRF2, IRF5, ISL1, ITGA3, JARID2, JUN, JUNB, JUND, JUP, KCNK2, KCNQ1, KIT, KRAS, AFF3, ABLIM1, LMO1, LTF, LUM, EPCAM, SMAD1, SMAD3, SMAD6, SMAD7, MAZ, MDH1, MDH2, MEIS1, MEN1, MEOX2, KITLG, MGMT, CIITA, ATXN3, MKI67, AFF1, FOXO4, ALDH6A1, CITED1, PPP1R12A, DRG1, TONSL, SLC11A2, NRF1, NRL, YBX1, NTF3, NTRK3, DDR2, NUP88, NUP98, NVL, OAS3, SIX6, ORC1, ORC2, ORC5, OTX1, OTX2, OVOL1, P2RY1, PA2G4, PCSK6, SERPINE1, PAM, PARK2, PAWR, PAX1, PAX2, PDCL, PAX9, PBX1, PCK1, CHMP1A, PDC, ENPP2, PDPK1, PEG3, PER1, PEX14, PFDN1, ATP8B1, PFN1, PGD, PGR, PHB, PHF2, PIM1, PRRX1, PPID, PPM1A, PPP4C, PPP3R1, PPP5C, PRIM1, PRIM2, PRKAB2, PRKAR1A, PRKCB, PRKCG, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK3, MAPK8, EIF2AK2, PROX1, PRPSAP1, RELN, PSMA6, PSMC1, PSMC3, PSMC4, PSMC5, PTAFR, PTBP1, PTCH1, PTGIS, PTMA, PTPN1, PTPN14, RAD1, PURA, QARS, RAC1, RAD51, RAD51B, RAD51D, RAG1, RAG2, RAN, RANBP2, RARA, RARB, RB1, ARID4A, RBBP4, RBBP6, RBBP8, RBL1, RBL2, RBM3, RBM4, RBMS1, RELB, DPF2, REST, REV3L, RFC1, RFC2, RFC3, RFC4, RFC5, RFX2, RFX3, RFX4, RFXAP, RHEB, RNASE1, RNF2, RNF6, RP9, RPA3, RPE, RPS6KA1, RPS6KA3, RREB1, RRM1, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A11, S100A12, SAFB, SALL1, SATB1, ATXN7, XCL1, SET, SFPQ, SFRP4, SFRP5, SRSF1, SRSF2, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SFSWAP, TRA2B, SGK1, SHC1, SHH, SIAH2, SIX1, SIX3, SLC5A5, SLC9A1, SLC11A1, SLC34A1, SNAI2, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCC2, SMARCD3, SMARCE1, SUMO3, SNAI1, SNAPC1, SNAPC2, SNAPC3, SNCB, SNAPC4, SNRNP70, SNRPA, SNRPA1, SNRPC, SNRPD1, SNRPD2, SNRPE, SNRPF, SNRPN, SOD2, SON, SOX1, SOX2, SOX3, SOX4, SOX5, SOX9, SOX10, SOX11, SOX12, SP1, SP2, SP3, SP4, SP100, UAP1, SPIB, SPTA1, SPTB, SQLE, SRD5A1, SREBF1, SRF, SRPK2, SRY, SSRP1, STAR, STAT2, STAT4, STAT5B, SUPT4H1, SUV39H1, SYK, T, TACR3, TAF2, TAF4B, TAF5, TAF6, TAF7, TAF13, TAL1, TARBP1, TARBP2, TARS, TBL1X, TBP, HNF1A, ZNF354A, PRDX2, NR2F1, NR2F2, KLF10, NR2E1, TMF1, TMPO, TNFAIP3, TNFRSF1A, TNNI2, TOP1, TOP2A, TP73, TPMT, NR2C1, NR2C2, TRAF1, TRAF2, TRH, CCT3, TRIP6, TRPC1, TRPS1, TSN, TSC1, TSC2, TSG101, TTF1, TULP3, TWIST1, TNFSF4, TNFRSF4, TYRP1, U2AF1, UBB, UBA7, UBE2D1, UBE2D2, UBE2L3, UBE2V1, UBE2V2, UBE3A, SUMO1, UBTF, UCP1, UFD1L, SCGB1A1, UGDH, UGP2, USP4, NR1H2, UROS, USF1, USF2, UVRAG, VAV1, VDR, EZR, WHSC1, WNT1, WNT2, WNT11, WRN, XPA, XPC, XRCC2, XRCC4, YWHAG, YWHAH, YWHAZ, ZFP37, ZFPL1, ZFX, ZIC1, ZIC2, ZNF3, ZNF711, ZNF7, ZNF8, CNBP, ZNF14, ZNF708, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF80, ZNF84, ZNF221, ZNF90, ZNF91, ZNF124, ZNF132, ZNF133, ZNF134, ZNF136, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, TRIM25, ZNF148, ZBTB17, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF180, ZNF189, ZNF207, ZNF214, ZNF223, ZNF224, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, ZP3, ZXDA, PRDM2, LRP8, PAX8, FZD5, BRPF1, AIMP2, MAFK, SHFM1, ARHGEF5, ZNF212, BRD3, NUP214, CUBN, CSRP3, PDHX, FOSL1, FGF23, AAAS, CDK2AP1, ANP32A, SF3A2, ZNF239, SYMPK, DPF1, NRIP1, CHAF1B, USP9X, RBM10, KDM5C, SMC1A, USP9Y, HIST1H4I, PICALM, CDC45, EOMES, FZD4, FZD6, FZD7, FZD8, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NR0B2, UTF1, CUL4B, CUL4A, CUL3, CUL2, FOXN1, TTF2, KLF11, FKBP6, PARG, KCNAB2, ITGA8, IKBKG, IKBKAP, HAT1, COPS3, CBX4, CAMK1, PIR, FCN3, BLZF1, MAPKAPK5, CDC14B, PDXK, RRP1, PRKRA, STK16, TNFSF11, KLF7, CDK13, RFXANK, TP63, CHRD, DDX3Y, DYNLL1, TNKS, SRSF9, TRADD, EDF1, URI1, EED, RNGTT, RIPK1, TNFSF13, RIPK2, SUCLG1, SUCLA2, CREG1, TRIM24, BANF1, SAP30, HESX1, CFLAR, HDAC3, TSC22D1, KAT2B, NR1I2, PER3, TAX1BP1, BUD31, CPNE1, BCL10, HERC2, PHOX2B, FUBP3, HIST1H3F, HIST1H2AG, USP13, RPS6KA4, TNFSF18, TAF1C, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, BTAF1, AIP, DIRAS3, USP2, PDLIM1, SMC3, PRPF3, CCNE2, CBFA2T2, DYRK1B, CTDP1, EXO1, COX7A2L, SCAF11, ARHGEF2, DDX21, BMP15, AURKB, VAPB, CCPG1, RPS6KA5, ITGB1BP1, ZNF235, KLF4, TRIP12, TRIP11, HMGN3, TRIP4, GTF3C5, GTF3C4, GTF3C3, EFTUD2, CER1, CIAO1, RECQL5, RECQL4, ZRANB2, SNRNP40, HAND1, QKI, EIF2AK3, FHL5, PICK1, HAND2, IL27RA, ATG5, ONECUT2, LITAF, TBPL1, ZNF254, TP53I3, CIR1, CHD1L, NR1D1, CLOCK, BRE, SOX13, RBM39, CREB5, WTAP, ABCG1, SNCAIP, NUP155, ZNF516, SAFB2, PHF14, KDM4A, VGLL4, NUP93, BZW1, KIAA0391, RAPGEF2, ST18, UTP14C, ZNF646, VPRBP, USP34, SETD1A, ZNF536, ZFYVE16, KIAA0101, BCLAF1, DHX38, SERTAD2, RNF40, TSC22D2, RB1CC1, GINS1, ZEB2, ZBTB24, ZNF518A, SETDB1, DDX46, SUPT7L, RNF10, ZBTB5, DCLRE1A, EXOG, USP3, SLC23A2, NR1I3, NR1H4, NR1D2, RBX1, DMTF1, PTBP3, CASP8AP2, NR2E3, SRA1, HDAC6, GNE, PARP2, PARP3, ABCB6, PQBP1, TSFM, RAD50, PREB, ZNF263, YAF2, G3BP1, SUGP2, CEBPZ, TRIM28, ZNF197, SORBS3, ALYREF, RNF41, DDX39A, OLIG2, TRIB1, ZNF443, DENND4A, SF3B4, IRX5, RAMP3, FSTL3, STAG1, CWC27, SAP18, SMNDC1, APBB3, CCNO, TNIP1, IKZF1, PCGF3, TRIM22, HMG20B, HMG20A, KLF2, CITED2, PRG3, PIAS3, IFITM3, NSA2, CD2BP2, RBM14, EMG1, PPIE, MAD2L2, SLC30A9, PPIH, TRIM38, CREB3, CARM1, ZNF211, DEAF1, CHERP, ATG7, BATF, RPP30, RPP38, SIVA1, CCT7, CCT4, CCT2, USP16, TBL3, ERLIN1, HEXIM1, RBCK1, ARID3B, IVNS1ABP, TRIM16, TXNIP, TAF6L, RAD51AP1, RGS14, SPHAR, DMRT2, KHDRBS1, KLF1, CTCF, FARS2, RRAGA, CCT8, USP39, CERS1, TBR1, STAG2, SIX2, RAI1, PTTG2, PHTF1, NUP50, ZMYND11, SRSF10, ZBTB6, ZNF234, ZNF266, UTP14A, ZNF275, SRCAP, RUVBL2, ARID5A, MALT1, CPSF4, BRD8, TXNL4A, PAPOLA, COPS8, DBF4, SRSF8, PRDX3, SF3A3, ASCC3, COPS6, SLC38A3, SF3B2, CCDC85B, ATF7, SNRNP27, VAX1, RBPMS, PIM2, PAPD7, ADRM1, CPSF6, WWP1, WWP2, DUS4L, SOX30, HSF2BP, WDR5, NUPL2, RPP14, KRR1, PRDM7, CLASRP, ERLIN2, SOX21, PSIP1, WDHD1, STRAP, BAZ2A, ZNF277, WBP4, SUPT16H, CHEK2, XPOT, SP140, SNF8, DDX19B, TREX1, KLF12, KLF8, DDX42, CTRC, PHB2, CBX3 |
2297 | GO:0044265 | 0.00 | 1.30 | 249.14 | 285 | 597 | cellular macromolecule catabolic process | AGXT, ANXA2, APC, ARNTL, ATM, BAX, BNIP3, BNIP3L, ZFP36L2, BUB1, BUB1B, CASP8, CAV3, CBL, CCNB1, CDC20, CDC27, CDKN2A, CENPF, CLU, CSNK1D, CSNK2A1, CSNK2A2, CTSK, CTSV, CTSS, CTSZ, CYLD, DAB2, DDB1, DDX6, DFFA, DFFB, DNASE1L1, DNASE1L2, DNASE1L3, DNASE2, DUSP1, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4G1, ERN1, FAP, FAU, FEN1, GPC1, GPX1, UBE2K, DNAJB2, HSP90AB1, IDE, EIF3E, ISG20, KPNA1, KPNB1, MAD2L1, SMAD7, DNAJB9, ATXN3, RPL10A, CNOT2, CNOT4, OAS2, OPHN1, PARK2, EXOSC9, PPP1R8, PPP2CB, PPP2R1A, PPP2R2A, PPT1, PRKACA, PRKCG, DNAJC3, PSMA1, PSMA2, PSMA4, PSMA5, PSMA6, PSMA7, PSMB1, PSMB2, PSMB4, PSMB5, PSMB7, PSMB10, PSMC1, PSMC3, PSMC4, PSMC5, PSMD1, PSMD2, PSMD3, PSMD4, PSMD5, PSMD7, PSMD8, PSMD11, PSME1, PSME2, RB1, RBBP6, RDX, RNASE2, RNASE3, RNASE6, RNF6, ABCE1, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, SDCBP, SEL1L, SETMAR, SGTA, SHH, SIAH1, SIAH2, SKP1, SKP2, SMARCC1, SUMO3, AURKA, SUPV3L1, TBL1X, TMF1, TNFAIP3, TSG101, TTC3, UBB, UBA7, UBE2D1, UBE2D2, UBE2H, UBE2L3, UBE3A, SUMO1, UFD1L, USP4, EZR, WFS1, WNT1, ZFP36, TRIM25, ZNF207, CSDE1, RNF103, RAB7A, CUL5, USP5, GAN, CLPP, USP11, USP9X, USP9Y, BAP1, CUL4B, CUL4A, CUL3, CUL2, CUL1, COPS3, PRPF18, KHSRP, RNASET2, CDC23, CTSF, RIPK1, CDC16, HERC2, USP13, RNF8, RPL14, USP14, USP6, USP2, RGN, RQCD1, AIFM1, ZW10, BUB3, AURKB, SOCS6, TRIP12, CNOT8, RPL23, UBE4A, PSMF1, BAG5, GTPBP1, NR1D1, CLOCK, RNF7, DZIP3, UBE3C, DHX34, USP34, DLGAP5, RNF40, CTIF, CUL7, RGP1, PSMD6, AREL1, SMG7, PAN2, USP3, RBX1, KCNE2, HDAC6, PDCD6IP, TOM1L1, RNF41, PSME3, TRIB1, MARCH6, ANAPC10, ARIH2, MAD2L2, TRIM38, RNASEH2A, ERN2, USP16, ERLIN1, RBCK1, YME1L1, GIPC1, USP19, RNPS1, SEC61B, OS9, WWP1, WWP2, UBE2C, ATE1, GLMN, ERLIN2, ADAMTS7, CHEK2, RPL35, RNF24, SNF8, USP18, EXOSC8 |
2298 | GO:0007010 | 0.01 | 1.29 | 177.07 | 203 | 428 | cytoskeleton organization | ABL2, ACTG1, ACTN4, ACTN1, ANG, ANXA1, BIRC5, AQP1, RND3, ARHGAP4, ARHGDIB, BBS2, BCL2, BICD1, BRCA2, BST2, CASQ2, CDC42, CENPA, CENPE, CHD3, CHD4, CNN1, CNN3, CNP, CRYAB, CSNK1D, CTNNA1, CTSV, CXADR, CYLD, DBN1, GADD45A, DIAPH1, DIAPH2, DNAH5, DYNC1H1, DPYSL3, ECT2, EFNA5, EML1, EMP2, EPB41, EPB41L2, EPHA3, EPHA5, EYA1, FGD1, FGF7, FLII, FLNA, GAPDH, GHSR, GOLGA2, GPM6B, CXCL1, HRG, ILK, INPPL1, INSRR, ITGB1, ITGB5, JUP, KISS1, KIT, KPNB1, KRAS, KRT4, KRT13, KRT19, LAMA5, ABLIM1, LLGL2, MAP6, MYO1B, PPP1R12A, NUMA1, OPHN1, PAM, PAWR, PCM1, CHMP1A, PDPK1, PEX14, PPP2R1A, PRKAR1A, PRKCI, PRKCZ, PRKG1, MAPK3, PYY, PTGER4, PTK7, PTPN1, RAB13, RAC2, RAC3, RALA, RAN, RAP2A, S100A8, S100A9, ATXN7, SDCBP, SHC1, STIL, SIPA1, SLC9A1, SLC16A1, SON, SOX9, SPAG1, SPAG4, SRF, SVIL, TACC1, CNTN2, TBCE, DYNLT1, TNNT2, TSC1, UGT8, CLRN1, UVRAG, EZR, CORO2A, WEE1, XRCC2, ZNF207, ALMS1, CSRP3, IFT88, GAN, SMC1A, UXT, CUL3, SORBS2, CDC42BPA, OFD1, CNTNAP1, CDC14A, DYNLL1, TNKS, RAB11A, CFLAR, HDAC3, PSTPIP2, MAP7, PRC1, LATS1, SMC3, ZW10, ZMYM6, PDLIM7, CYTH2, S1PR2, TRIP10, TAOK2, SLC9A3R1, KIF3B, NRXN1, NRXN2, CRIPT, BCAR1, CDC42BPB, CEP135, CROCC, CEP57, SEMA3E, CCP110, SLK, KIAA0101, CKAP5, CUL7, ARHGEF17, ELMO1, KIAA0753, FARP2, KIAA0196, ABI1, PDCD6IP, PARP3, RANBP9, KIF20A, FRY, AKAP9, TRDN, TUBA1B, CORO2B, MAD2L2, TACC3, CAP2, CAP1, TACC2, SORBS1, RGS14, DCTN6, TPPP, CAPN10, KPTN, CHEK2, FZD10, GABARAP |
2299 | GO:0071705 | 0.04 | 1.29 | 84.53 | 97 | 207 | nitrogen compound transport | AQP6, ARG1, ATP1A2, AVP, CACNB4, CCK, CRYM, CTNS, DDC, EIF4E, EIF5A, SLC29A1, GIF, GJB1, GLE1, GLS, HHEX, AGFG1, KCNJ10, SEPT2, NTRK2, NTSR1, NUP88, NUP98, OAZ1, OAZ2, P2RX7, RAB3A, RAN, RANBP2, RPS28, SRSF1, SRSF2, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SLC1A6, SLC1A7, SLC6A6, SLC6A7, SLC6A8, SLC6A11, SLC6A12, SLC6A13, SLC7A1, SLC7A4, SLC11A1, SYT1, SERPINA7, TRPC4, TSC1, TST, U2AF1, XK, NUP214, CUBN, AAAS, SLC7A5, KHSRP, TNKS, SRSF9, RIPK1, SLC6A5, SLC22A13, QKI, NUP155, NUP93, DHX38, CKAP5, TOMM20, SMG7, SLC23A2, SLC25A13, SLC25A15, ALYREF, DDX39A, SLC35B1, SLC25A17, NXF1, UNC13B, ARL6IP5, SLC35A1, IGF2BP3, KHDRBS1, GIPC1, NUP50, SRSF10, RNPS1, SERINC3, SLC35D2, NUPL2, SLC7A9, PRAF2, XPOT, DDX19B |
2300 | GO:0030154 | 0.02 | 1.28 | 118.98 | 137 | 318 | cell differentiation | AAMP, ADCYAP1R1, ADD1, ADRB2, AP1G1, ALAS2, ANPEP, PHOX2A, ASTN1, BLK, BNIP3, BRDT, DAGLA, CCIN, CDX1, CDX4, CENPF, TBCB, CLCN2, COL19A1, ATF2, CSPG4, CYLC1, DAZ1, DFNA5, DHCR7, DNASE2, DNMT1, DNMT3A, TYMP, EDA, ELAVL3, ELF1, ELK1, ELK3, EML1, EMX2, ETV3, ETV6, EVX1, EXT2, FABP7, FECH, FGR, FOXD1, FLT1, FRK, NR5A1, GAS1, GPM6B, HIST1H1T, HCK, HIP1, NR4A1, HMX2, HOXC10, FOXK2, KCNA1, LLGL2, SMAD6, MAL, MEA1, ALDH6A1, ODF1, OMP, P2RY1, PGF, PTPRR, PURA, RFNG, RGS2, RPS3A, SFRP5, SRSF4, SHB, SLC2A4, SMARCA1, SMARCC2, SMARCE1, SOX12, SPIB, SRD5A1, SRMS, SRPK2, SRY, SUV39H1, TACC1, NR2F1, TNFAIP2, TNP2, TOP2A, TSPY1, TULP3, TYK2, UBE2V1, UCP1, ZIC1, ZIC2, ZNF3, SLC7A5, SOAT2, FKBP6, KCNAB2, DCHS1, TNK1, TNFSF12, DLK1, PEX11A, AP1M1, CDK5R2, INA, KRT75, AIFM1, BCL7B, ZNF516, UTP14C, FAM65B, SNPH, SPATA2, ZBTB24, SRA1, SH2B3, PTPRU, ARL4A, TNK2, COQ7, CITED2, TACC3, TACC2, KLF1, CSPG5, VAMP5, CPLX2, EDAR, PRDX3, RAB32, FZD10 |
2301 | GO:0022402 | 0.01 | 1.27 | 191.06 | 217 | 466 | cell cycle process | ACVR1, ACVR1B, ADCY3, ATR, BACH1, BBS4, BCAT1, BCL2, BCL2L1, BID, BMP4, BRCA2, BRDT, CALM3, CAMK2A, CAMK2G, CAV2, CCNE1, CCNG2, CCNH, CDC5L, CDC25C, CDK3, CENPA, CETN1, CHD3, CHD4, CKS1B, CLTC, ATF2, CRY1, CSNK1D, CYP27B1, DDB1, DDX11, DHFR, DIAPH2, DLG1, DYNC1H1, DYNC1I2, DNM2, E2F4, EIF4E, EIF4EBP1, EML1, EMD, ENSA, EP300, EPS8, ERCC3, EYA1, FANCA, FANCD2, FANCG, FGFR3, FLNA, GEM, GFI1, GOLGA2, GPR3, HGF, PRMT2, HSP90AA1, INCENP, ING2, ITGB1, KIF25, KPNB1, LLGL2, RAB8A, MEN1, MKI67, PPP1R12A, PPP1R12B, NUBP1, SEPT2, NUMA1, NUP88, NUP98, ODF2, ORC2, ORC5, OVOL1, PCM1, CHMP1A, PDE3A, ABCB1, PIK3C3, PIM1, SEPT5, PPP2R2A, PPP5C, PPP6C, PRCC, PRKAR1A, PRKAR2B, PRKCA, PRKCB, PRKCQ, PTPN6, RAD1, RAD51, RAD51D, RALA, RAN, RANBP2, RBBP4, RBBP8, RPL24, RPS3, RPS6KA2, RRM2, CLIP1, STIL, SIX3, SKP1, SKP2, SMARCA4, SON, SOX9, SOX11, TAF2, DYNLT3, DYNLT1, TPD52L1, TUBA4A, TYMS, UBE2L3, UVRAG, EZR, VRK1, WEE1, XPC, XRCC2, YWHAG, ALMS1, TUBA1A, NUP214, AAAS, CLTCL1, USP9X, KLF11, FKBP6, OFD1, PPM1D, CDC14B, CDK13, SSNA1, DYNLL1, TNKS, PEA15, BANF1, HDAC3, RNF8, PRC1, LATS1, CCNB2, CCNE2, CTDP1, ARHGEF2, TAOK2, CLOCK, BRE, MAD2L1BP, NUP155, CEP135, NUP93, CEP57, KNTC1, CCP110, CKAP5, IST1, SFI1, CUL7, KIAA0753, KIAA0196, DCLRE1A, PDCD6IP, PARP3, TOM1L1, SMC4, ACTR2, CTDSP2, RAD50, KIF20A, FEM1B, ACTR1A, AKAP9, CTDSPL, AKAP8, STAG1, KATNB1, TUBGCP3, RBM14, TACC3, SSSCA1, TACC2, USP16, STAMBP, PDPN, RGS14, CTCF, DCTN6, STAG3, NUP50, ARPP19, JTB, TXNL4A, DBF4, RAB35, PIM2, PAPD7, NUPL2, ZWINT, DCTN3, ECD, OIP5 |
2302 | GO:0051716 | 0.00 | 1.27 | 615.00 | 686 | 1720 | cellular response to stimulus | A2M, ABAT, ABCA4, ACTB, ACTG1, ACTN4, ACVR1B, ADA, ADORA1, ADRA1B, ADRA2C, ADRBK2, AP1G1, AGXT, ALK, ALOX15B, ANXA2, ANXA4, ANXA6, BIRC5, APLP2, APOC2, KLK3, SHROOM2, AREG, ARF1, ARF4, ARL4D, ARF5, ARF6, RND3, ARHGAP5, ARHGAP6, ARHGDIB, ARHGDIG, RHOH, ARL1, ARL2, ARR3, ASGR2, ATOH1, AVP, ADGRB2, BCL9, OPN1SW, BICD1, BIK, BLK, BMX, DST, BRS3, BSG, BTK, BUB1, BUB1B, C3, CAPN5, DAGLA, CACNA1A, CACNA1F, CACNB4, CALCR, CAMLG, CASP10, CBLB, CCK, KRIT1, CCND3, CD2, CD3D, CD3G, CD4, CD5, CD7, CD8A, TNFSF8, CD37, CD38, CD53, CD59, CD72, CD79B, ADGRE5, CD151, CDA, CDC20, CDC25C, CDH3, CDH6, CDH17, CDK4, CDK5, CENPA, CENPE, CENPF, CGA, CHKA, CHN1, CHN2, CHRM1, CHRM3, CHRNB2, CHRNB4, CLCN6, CLPS, LTB4R, CNR1, CNR2, COL4A3, CORT, CLDN3, CR1, CR2, CREBL2, CRYBA1, CSNK1G2, CSNK1G3, CSNK2A1, CSPG4, CTF1, CTNND1, CTNND2, DGKA, DGKB, DGKQ, DBH, DCC, DCX, DFNA5, DHCR24, DIAPH2, DMBT1, DNM1, DOK1, RCAN1, DTNA, DTX1, E2F2, GPR183, S1PR1, S1PR3, EFNA1, EFNA3, EFNA4, EFNB2, CELSR2, EIF2B1, ELF1, ELK3, EMP2, ADGRE1, EPHA1, EPHA7, EPHA8, EPHB2, EPHB3, EPS8, EPS15, ERG, EVC, EXT1, EXT2, F2R, F10, FBLN1, EFEMP1, FCER2, FCGR2A, FCGR2B, FCGRT, FCN1, GPC4, FGF11, GPC5, FGG, FGR, FLNA, FLT3LG, FPR1, FPR2, FPR3, FRK, CENPI, GAST, FYB, GABRA4, GABRE, GABRG1, GABRR1, GABRR2, GALR1, GAP43, OPN1MW, GDI1, GDI2, GDNF, GEM, GFRA1, B4GALT1, GHRH, GIP, GLRB, GMDS, GNA15, GNAI3, GNAL, GNAQ, GNAT2, GNAZ, GNGT2, GNRH2, GPR1, GPR3, GPR4, GPR15, GPR25, GPR26, FFAR1, GRK6, GRB7, GRIA1, GRIA4, GRID1, GRID2, GRN, GRIK3, ARHGAP35, GRM8, GRPR, GTF2I, GUCY2C, H3F3B, HIP1, HIVEP2, HOXD3, HRC, HRH2, HTR2C, IAPP, ICAM2, SP110, IGF2R, IGFBP3, IGFBP6, IHH, IMPA1, IMPA2, INCENP, INHA, INPP1, INPP4A, INSL3, INSL4, ITGA7, ITGAD, ITGAE, ITGAL, ITGAM, ITGAV, ITGAX, ITGB4, ITPKB, CD82, KCNA5, KCNN4, KIF5A, KISS1, KLK2, KLRB1, KLRC2, KLRC3, KLRD1, KLC1, KRT19, LAMA5, LIMK1, LLGL2, LRPAP1, LSP1, BCAM, TACSTD2, EPCAM, MAD2L1, MAL, CD46, PPP1R12A, PPP1R12B, SEPT2, NRTN, NTF3, NTF4, DDR2, NTSR1, OCRL, OMP, OPHN1, OR1D2, OR1F1, OR2C1, OR3A1, OR3A2, OXT, P2RX3, PDCL, PDC, PDE4C, PDE6H, PDE7A, PDE8A, PDGFRL, ENPP2, PDYN, PGAM2, PIGR, PIK3C2B, PI4KA, PI4KB, PLN, PPP1R1A, PPP1R2, PPP2R1B, PPP3R1, SRGN, PRKCSH, RELN, KLK6, PYY, TAS2R38, PTGER1, PTHLH, PTH1R, PTH2R, PTPN13, PTPRD, PTPRJ, PTPRM, PTPRR, RAB1A, RAB3A, RAB3B, RAB4A, RAB6A, RAB27A, RAB27B, RABIF, RAB5C, RAC3, RAP1GDS1, RAP2B, RBP1, RBP2, OPN1LW, PRPH2, DPF2, RFNG, RFX4, RGR, RGS1, RGS2, RGS10, RGS13, RGS16, RLN1, RLBP1, RPS27, RRAS, RREB1, CLIP1, RSU1, S100A1, S100A4, S100A6, S100A11, S100A13, SALL1, TSPAN31, ATXN7, SCTR, SDC1, SDC2, SDC4, SEC14L1, SELE, SELP, SEMA3F, SFRP5, SH3BGR, SH3BGRL, SH3BP2, SHB, SIAH1, SIAH2, STIL, SIX3, SLA, SLC20A1, SLIT1, SMPD1, SIGLEC1, SORL1, SOX2, SOX10, SPINK1, SPN, SRMS, SRPK2, STRN, STYX, TACR2, TACR3, CNTN2, TBL1X, DYNLT1, TSPAN7, TNFAIP6, TPTE, TRHR, TRIP6, TRPC3, TRPS1, TSG101, TSHB, TUFT1, TULP3, TYRO3, TYROBP, UPK1B, UCN, SCGB1A1, KDM6A, VDAC2, VIM, VIP, VIPR1, VIPR2, LAT2, CORO2A, YWHAZ, ZIC1, ZIC2, ZP2, ZP3, SEMA3B, FZD3, STAM, CUL5, ANP32A, RND2, MADCAM1, CLTCL1, FZD6, FZD9, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, OR1A1, OR1E1, OR1E2, OR1G1, OR3A3, SPARCL1, BCAR3, SORBS2, CDC42BPA, SEMA7A, CNTNAP1, IKBKAP, DGKE, CAMK1, OR6A2, RFXANK, UNC5C, SSNA1, DCHS1, PTCH2, NUMB, PDE5A, DYNLL1, TNKS, S1PR4, TNK1, CTNNAL1, HRK, TNFSF10, TNFSF9, ADAM15, RAB11A, RGS11, DLK1, PEX11A, INPP4B, CFLAR, WISP3, WISP1, HCAR3, AKAP4, SGPL1, EIF2B2, AP1M1, WASF1, AP3D1, HIST1H3F, PGLYRP1, RHBDL1, TAAR5, DOK2, PSTPIP1, PRC1, ANGPTL1, DIRAS3, DGKI, RASSF9, ZW10, BUB3, REPS2, DCLK1, XPR1, VAPA, CRLF1, GPR50, DHRS3, STK17B, STK17A, CYTH3, CYTH2, BCL7B, TAAR2, GPR55, GPR52, S1PR2, TRIP10, RAB9A, SLC9A3R1, NRXN3, NRXN2, ARHGAP29, ECEL1, HAND2, THEMIS2, RAB3D, GTPBP1, GABBR2, CDC42BPB, RAB36, RIN1, AATK, GNA14, ZNF516, SDC3, TTI1, PHF14, PUM1, RIMS2, SEMA3E, KNTC1, USP34, GPRASP1, IFT140, ZNF536, RAPGEF5, SNX17, KIAA0586, CKAP5, SPOCK2, KIAA0141, ELMO1, GAB2, FARP2, TRIL, RHOBTB1, DENND4B, P2RY14, ARHGAP25, ABI1, SRA1, SH2B3, FRAT1, TOM1L1, HMGXB4, RANBP9, ABCC9, PTPRU, GPC6, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, TSPAN2, TSPAN1, ARPC2, SGK2, ARL4C, ARL4A, ARFRP1, G3BP1, ABI2, ATP6AP2, FARP1, WASF2, SORBS3, TNK2, RNF41, RCAN2, STAM2, AKAP8, EFS, SIGMAR1, APC2, TNIP1, TRDN, ABCA7, CACNG2, SEMA3A, CDC42EP2, OLFM1, CAP2, CAP1, UNC13B, SEMA6C, SEMA6B, SEMA4F, SEMA4B, PRDX4, ARPC1A, OLFM4, ARFGEF2, ARFGEF1, SIVA1, CDC42EP3, HEXIM1, STAMBP, IVNS1ABP, TRIM16, PDPN, RASL10A, KHDRBS1, EBP, RRH, CNPY3, NRG3, GRAP, CHL1, TRAF3IP2, AHCYL1, OR5I1, STARD10, PDE10A, CD300C, PROKR1, MALT1, BRD8, RAB40B, RAB32, IFT27, RBPMS, ADAP1, PIM2, UPK1A, OGFR, WWP1, RAPGEF4, ESM1, ADAMTS13, CIT, RCAN3, CD160, ZWINT, CDC42EP1, IL1RAPL1, RABL2B, RABL2A, AKAP11, AKAP10, RASSF8, GPR176, NXPH4, NXPH3, GPR45, PTGDR2, HRH3, GPR182, STK38, GABARAP |
2303 | GO:0048646 | 0.04 | 1.26 | 102.01 | 116 | 251 | anatomical structure formation involved in morphogenesis | ACTG1, ACTN1, ADA, ALDH1A3, PHOX2A, ATP2B2, BBS1, BBS2, BCL3, BYSL, CACNA1A, CACNA1S, CASP9, CASQ2, CAV3, CD9, CD36, CD53, CFL2, CHAD, COL1A1, ATF2, CSNK1D, CYLD, DLX5, DLX6, DNAH5, E2F4, CELSR2, EGR2, ERCC1, FGF3, FOXD1, FLNA, FLT3LG, GPC1, GRB2, GRID2, ONECUT1, HOXC11, HOXD11, AGFG1, HES1, ILK, ITGA6, JUNB, KRT19, ABLIM1, RAB8A, SEPT2, CNOT2, NTF4, OCRL, ODF2, PCM1, ATP8B1, MAPK3, PTHLH, PTPN6, RFX3, RFX4, RPGR, RS1, SLC34A1, SMARCD3, SP1, SP3, SPAG1, TMF1, TMOD1, TNNT2, TRPS1, UGT8, WNT1, WNT2, WNT2B, ZP3, CSRP3, IFT88, CUL3, OFD1, CNTNAP1, CAMK1, CDC14A, TP63, TNFSF14, TNFSF13, ADAM9, HESX1, CFLAR, PROM1, AKAP4, HAP1, LATS1, ATP6V0D1, DYRK1B, SNAP29, ATG5, ONECUT2, ADAMTS1, GDF15, TBPL1, IQCB1, IFT140, KIAA0586, FIG4, WDR1, ACTR2, ABCC4, CCNO, CITED2, TNFSF13B, TBR1, SEPT9, EHD1, KIF3A |
2304 | GO:0090304 | 0.00 | 1.26 | 1141.39 | 1249 | 2735 | nucleic acid metabolic process | AARS, ABCA2, ACHE, ACTN4, ACTL6A, ACTN1, ACVR1, ACVR1B, ACVR2A, ACVR2B, ACVRL1, ADAR, ADARB1, PARP4, ADRB2, AEBP1, AES, AGTR2, NR0B1, AHR, AKT2, ALK, ALX3, ANG, ANXA1, ANXA3, ANXA4, APBB1, XIAP, BIRC5, AREG, ARF4, RHOH, PHOX2A, ARNT, ARNTL, ASCL2, ATF3, ATF4, ATM, RERE, ATOH1, ATR, ATRX, AZGP1, BACH1, BARD1, BAX, CCND1, BCL3, BCL7A, BCL9, BICD1, PRDM1, BMI1, BMP1, BMP4, BMP6, BMP8B, BMPR1A, BMPR2, BRCA1, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTG1, BTK, BYSL, C1QBP, CAMK4, CAMK2A, CAT, RUNX2, RUNX1T1, CBFB, CBL, CBS, CCNB1, CCNC, CCNE1, CCNH, CCNT1, CCNT2, CD3D, CD28, CD80, CD86, TNFSF8, CD36, CD38, CD40, CDC5L, CDC6, CDC25C, CDC42, CDH1, CDK5, CDK8, CDK9, CDKN1A, CDKN2A, CDKN2D, CDX1, CDX2, CDX4, CEBPE, CEBPG, CENPB, CENPF, CGA, CHD1, CHD2, CHD3, CHD4, CHUK, CLU, CLK3, CLNS1A, CMKLR1, COL1A1, COX4I1, COX5B, COX6A1, COX6B1, COX7B, COX7C, COX8A, ATF2, CREBL2, CRX, CRY1, CRY2, CRYM, CSF2, CSNK1D, CSNK2A1, CSNK2A2, CSTF3, CTGF, CTH, CTNND1, CTNND2, CUX1, CYLD, DAB2, DGKQ, DARS, DCN, DDB1, DDB2, GADD45A, DDX1, DDX3X, DDX5, DDX6, DHX8, DHX9, DDX10, DFFA, DFFB, DHFR, DLG1, DLX3, DLX5, DLX6, DNASE1L1, DNASE1L2, DNASE1L3, DNASE2, DNM2, DNMT1, TRDMT1, DNMT3A, DNMT3B, DNTT, ARID3A, ATN1, RCAN1, TSC22D3, DTX1, DUSP1, DUT, DYRK1A, E2F2, E2F4, E2F5, E4F1, EBF1, TYMP, ECM1, EDA, S1PR1, EDNRB, EFNA1, CELSR2, EGR2, EGR3, EGR4, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4G1, ELAVL2, ELF1, ELF3, ELK1, ELK3, EMX1, EMX2, EN1, EP300, EPHA5, EPRS, ERBB2, ERCC1, EREG, EYA4, ERCC3, ERCC4, ERCC5, ERCC6, ERG, ERN1, ESR1, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA1, EYA2, EYA3, EZH1, F2R, F2RL1, FANCA, FANCC, FANCD2, FANCE, FANCG, FAU, FBN1, EFEMP1, FEN1, FGF1, FGF7, FGF8, FGF9, FGFR3, FGFR4, FOXD1, FLI1, FLII, FLNA, AFF2, FRK, NR5A1, GABPA, GALR1, GARS, GAS6, GATA3, GATA4, GATA6, GCG, KAT2A, NR6A1, GDF9, GDNF, GFI1, GPC3, GLS, GNAS, SFN, GPS2, GPX2, ARHGAP35, GRSF1, GSC2, GTF2F1, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AE, HIST1H2AD, H2AFZ, H3F3B, HSD17B10, HARS, HAS3, HCK, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIF1A, HIP1, HIVEP2, HLF, HLX, HMGN1, HMGA1, NR4A1, HMX1, HMX2, FOXA2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD3, HOXD4, HOXD8, HOXD11, HPN, PRMT2, PRMT1, HES1, HSBP1, HSPA8, ICAM1, IFI16, SP110, IFNA2, IFNG, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL1B, IL10, FOXK2, ILK, ING2, INS, INSIG1, EIF3E, IRAK1, ITGA6, IRAK2, IRF1, IRF2, IRF5, ISG20, ISL1, ITGA3, JARID2, JUN, JUNB, JUND, JUP, KCNK2, KIT, KPNA1, KPNB1, KRAS, AFF3, ABLIM1, LMO1, LTF, LUM, EPCAM, SMAD1, SMAD3, SMAD6, SMAD7, MAZ, MEIS1, MEN1, MEOX2, KITLG, MGMT, CIITA, ATXN3, MKI67, AFF1, FOXO4, CITED1, NUDT1, PPP1R12A, DRG1, RPL10A, TONSL, CNOT2, CNOT4, NRF1, NRL, YBX1, NTF3, NTHL1, NTRK1, NTRK3, DDR2, NUP88, NUP98, NVL, OAS1, OAS2, OAS3, OGG1, SIX6, ORC1, ORC2, ORC5, OTX1, OTX2, OVOL1, P2RY1, PA2G4, PCSK6, SERPINE1, PAM, PARK2, PAWR, PAX1, PAX2, PAX9, PBX1, PCK1, CHMP1A, PDE8A, ENPP1, ENPP2, ENPP3, PDPK1, PEG3, PER1, PEX14, PF4, PFDN1, ATP8B1, PFN1, PGR, PHB, PHF2, PIM1, EXOSC9, PRRX1, PPID, PPM1A, PPP1R8, PPP2R1A, PPP2R2A, PPP4C, PPP3R1, PPP5C, PRIM1, PRIM2, PRKAA1, PRKAB2, PRKAR1A, PRKCB, PRKCG, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK3, MAPK8, EIF2AK2, PROX1, RELN, PSMA6, PSMC1, PSMC3, PSMC4, PSMC5, PTAFR, PTBP1, PTCH1, PTGIS, PTHLH, PTMA, PTPN14, RAD1, PURA, QARS, RAC1, RAD51, RAD51B, RAD51D, RAF1, RAG1, RAG2, RAN, RANBP2, RARA, RARB, RB1, ARID4A, RBBP4, RBBP6, RBBP8, RBL1, RBL2, RBM3, RBM4, RBMS1, RELB, DPF2, REST, REV3L, RFC1, RFC2, RFC3, RFC4, RFC5, RFX2, RFX3, RFX4, RFXAP, RHEB, RNASE1, RNASE2, RNASE3, RNASE6, RNF2, RNF6, ABCE1, RP9, RPA3, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS2, RPS3, RPS3A, RPS4X, RPS4Y1, RPS6, RPS6KA1, RPS6KA3, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS27A, RPS28, RPS29, RREB1, RRM1, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A11, S100A12, SAFB, SALL1, SATB1, ATXN7, XCL1, SET, SETMAR, SFPQ, SFRP4, SFRP5, SRSF1, SRSF2, SRSF3, SRSF4, SRSF5, SRSF6, SRSF7, SFSWAP, TRA2B, SGK1, SHC1, SHH, SIAH2, SIX1, SIX3, SLC9A1, SLC11A1, SNAI2, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCC2, SMARCD3, SMARCE1, SUMO3, SNAI1, SNAPC1, SNAPC2, SNAPC3, SNAPC4, SNCA, SNRNP70, SNRPA, SNRPA1, SNRPC, SNRPD1, SNRPD2, SNRPE, SNRPF, SNRPN, SOD2, SON, SOX1, SOX2, SOX3, SOX4, SOX5, SOX9, SOX10, SOX11, SOX12, SP1, SP2, SP3, SP4, SP100, SPIB, SREBF1, SRF, SRPK2, SRY, SSRP1, STAT2, STAT3, STAT4, STAT5B, SUPT4H1, SUPV3L1, SUV39H1, SYK, T, TAF2, TAF4B, TAF5, TAF6, TAF7, TAF13, TAL1, TARBP1, TARBP2, TARS, TBL1X, TBP, HNF1A, ZNF354A, PRDX2, NR2F1, NR2F2, KLF10, NR2E1, TMF1, TMPO, TNFAIP3, TNFRSF1A, TNNI2, TOP1, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, CCT3, TRIP6, TRPS1, TSN, TSC1, TSC2, TSG101, TTF1, TULP3, TWIST1, TNFSF4, TNFRSF4, TYMS, U2AF1, UBB, UBA7, UBE2D1, UBE2D2, UBE2L3, UBE2V1, UBE2V2, UBE3A, SUMO1, UBTF, UCN, UCP1, UFD1L, SCGB1A1, UNG, USP4, NR1H2, USF1, USF2, UVRAG, VAV1, VDR, VEGFA, EZR, WFS1, WHSC1, WNT1, WNT2, WNT11, WRN, XPA, XPC, XRCC2, XRCC4, YWHAG, YWHAH, YWHAZ, ZFP36, ZFP37, ZFPL1, ZFX, ZIC1, ZIC2, ZNF3, ZNF711, ZNF7, ZNF8, CNBP, ZNF14, ZNF708, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF80, ZNF84, ZNF221, ZNF90, ZNF91, ZNF124, ZNF132, ZNF133, ZNF134, ZNF136, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, TRIM25, ZNF148, ZBTB17, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF180, ZNF189, ZNF207, ZNF214, ZNF223, ZNF224, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, ZP3, ZXDA, PRDM2, LRP8, CSDE1, PAX8, FZD5, BRPF1, AIMP2, MAFK, SHFM1, ARHGEF5, ZNF212, BRD3, NUP214, CSRP3, FOSL1, FGF23, AAAS, CDK2AP1, ANP32A, SF3A2, ZNF239, SYMPK, DPF1, NRIP1, CHAF1B, USP9X, RBM10, KDM5C, SMC1A, USP9Y, HIST1H4I, PICALM, CDC45, EOMES, FZD4, FZD6, FZD7, FZD8, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NR0B2, UTF1, CUL4B, CUL4A, CUL3, CUL2, FOXN1, TTF2, KLF11, FKBP6, OGT, PARG, ITGA8, IKBKG, IKBKAP, HAT1, COPS3, CBX4, CAMK1, PIR, FCN3, BLZF1, MAPKAPK5, CDC14B, PRPF18, RRP1, KHSRP, PRKRA, STK16, TNFSF11, KLF7, CDK13, RFXANK, TP63, RNASET2, CHRD, DDX3Y, DYNLL1, TNKS, SRSF9, TRADD, EDF1, URI1, EED, RNGTT, RIPK1, TNFSF13, RIPK2, CREG1, TRIM24, BANF1, SAP30, HESX1, CFLAR, HDAC3, TSC22D1, KAT2B, NR1I2, PER3, TAX1BP1, BUD31, CPNE1, BCL10, HERC2, PHOX2B, MBD4, FUBP3, HIST1H3F, HIST1H2AG, USP13, RPS6KA4, TNFSF18, TAF1C, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, BTAF1, RPL14, AIP, USP2, RGN, PDLIM1, RQCD1, SMC3, PRPF3, AIFM1, CCNE2, CBFA2T2, DYRK1B, CTDP1, EXO1, COX7A2L, SCAF11, ARHGEF2, DDX21, BMP15, AURKB, CCPG1, RPS6KA5, ITGB1BP1, ZNF235, KLF4, TRIP12, TRIP11, HMGN3, TRIP4, GTF3C5, GTF3C4, GTF3C3, CNOT8, EFTUD2, RPL23, CER1, COX5A, CIAO1, RECQL5, RECQL4, ZRANB2, SNRNP40, HAND1, QKI, EIF2AK3, FHL5, PICK1, HAND2, IL27RA, ATG5, ONECUT2, LITAF, TBPL1, ZNF254, CIR1, CHD1L, GTPBP1, NR1D1, CLOCK, BRE, SOX13, RBM39, CREB5, WTAP, ABCG1, NUP155, ZNF516, SAFB2, PHF14, KDM4A, VGLL4, NUP93, BZW1, KIAA0391, DHX34, ST18, UTP14C, ZNF646, VPRBP, USP34, SETD1A, ZNF536, HDAC4, ZFYVE16, KIAA0101, BCLAF1, DHX38, SERTAD2, RNF40, CTIF, TSC22D2, RB1CC1, GINS1, ZEB2, ZBTB24, ZNF518A, SETDB1, DDX46, SMG7, SUPT7L, RNF10, PAN2, ZBTB5, DCLRE1A, EXOG, USP3, NR1I3, NR1H4, NR1D2, RBX1, DMTF1, PTBP3, CASP8AP2, NR2E3, SRA1, HDAC6, PARP2, PARP3, PQBP1, TSFM, RAD50, PREB, ZNF263, YAF2, G3BP1, SUGP2, CEBPZ, TRIM28, ZNF197, SORBS3, ALYREF, RNF41, DDX39A, OLIG2, TRIB1, ZNF443, COQ7, DENND4A, SF3B4, IRX5, RAMP3, FSTL3, STAG1, CWC27, SAP18, SMNDC1, APBB3, CCNO, TNIP1, IKZF1, PCGF3, TRIM22, HMG20B, HMG20A, KLF2, CITED2, PIAS3, IFITM3, RAPGEF3, NSA2, CD2BP2, RBM14, EMG1, PPIE, MAD2L2, SLC30A9, PPIH, TRIM38, CREB3, CARM1, ZNF211, DEAF1, CHERP, ATG7, RNASEH2A, BATF, RPP30, RPP38, SIVA1, CCT7, CCT4, CCT2, ERN2, USP16, TBL3, ERLIN1, HEXIM1, RBCK1, ARID3B, IVNS1ABP, TRIM16, TXNIP, TAF6L, RAD51AP1, RGS14, SPHAR, DMRT2, KHDRBS1, KLF1, CTCF, FARS2, RRAGA, CCT8, USP39, CERS1, TBR1, STAG2, SIX2, RAI1, PTTG2, PHTF1, NUP50, AHCYL1, ZMYND11, SRSF10, ZBTB6, ZNF234, ZNF266, UTP14A, ZNF275, SRCAP, RUVBL2, ARID5A, MALT1, CPSF4, BRD8, TXNL4A, PAPOLA, COPS8, RNPS1, DBF4, SRSF8, PRDX3, SF3A3, ASCC3, COPS6, SLC38A3, SF3B2, CCDC85B, ATF7, SNRNP27, VAX1, RBPMS, PIM2, PAPD7, ADRM1, CPSF6, WWP1, WWP2, DUS4L, SOX30, HSF2BP, WDR5, NUPL2, RPP14, KRR1, PRDM7, CLASRP, ERLIN2, SOX21, PSIP1, WDHD1, STRAP, BAZ2A, ZNF277, WBP4, SUPT16H, CHEK2, RPL35, XPOT, SP140, SNF8, DDX19B, TREX1, KLF12, KLF8, ECD, DDX42, PHB2, CBX3, EXOSC8 |
2305 | GO:0034613 | 0.03 | 1.26 | 115.52 | 131 | 284 | cellular protein localization | ABL2, ADORA1, AP2A1, AP2B1, AP1G1, ANXA2, ATP1B3, BSG, CACNA1A, CALCR, CD4, CD63, CD74, AP1S1, AP2S1, AP3S1, CLTA, COPA, COPB1, CTNNA1, DBN1, DLG2, DLG3, DPP6, EGR2, EIF5A, CTTN, ETV5, EYA1, FCER1G, FLOT2, FNTA, GAS8, GLRB, GRID2, IFIT1, ITGA4, ITGAL, KCNA1, KRT18, LAMA5, LTBP2, SMAD7, RAB8A, NUBP1, OXA1L, P2RY1, PIGR, PRKCZ, RELN, PTCH1, RAB13, RAB27A, RAC1, RAP2A, RPGR, CLIP1, RTN2, S100A10, SCP2, SDCBP, SEL1L, SLC12A1, SPAG4, STXBP1, STYX, CNTN2, DYNLT1, TNFAIP2, TNFRSF1A, UFD1L, UGT8, ZP2, ZP3, STAM, MADCAM1, CLTCL1, CNTNAP1, BLZF1, USO1, SSNA1, STX16, STX11, STX10, LIN7A, AP1S2, AP1M1, HERC2, MAP7, LATS1, AP4M1, ARHGEF2, RASSF9, COPB2, TAOK2, NRXN2, PICK1, RAPGEF2, RIMS2, SNX17, HDAC6, PDCD6, TOM1L1, TOM1, AP1M2, AP3S2, STAM2, RAMP2, KATNB1, SEC24B, SEC23B, SEC23A, APPBP2, RRAGA, AP4B1, GIPC1, AHCYL1, VAMP5, SEC24A, AP3M2, ERP29, TMED10, FERMT2, IFT27, RAB31, NUPL2, CDC37, WDR45, XPOT, GABARAP, TWF2 |
2306 | GO:0048285 | 0.02 | 1.26 | 138.97 | 157 | 333 | organelle fission | ACOX1, ADCY3, APC, BIRC5, ATM, ATRX, BAX, BMP4, BNIP3, BRCA2, BRDT, BUB1, BUB1B, CAV2, CCNB1, CCNG2, CD28, CDC6, CDC20, CDC25C, CDC27, CDC42, CDK3, CENPE, CENPF, CETN1, CLTC, CSNK2A1, CSNK2A2, DCN, DHODH, DUSP1, E4F1, EDN3, ENSA, EPS8, EREG, ERCC4, FANCA, FANCD2, FGF8, FGFR3, FLNA, GEM, GOLGA2, GPR3, HGF, IGF1, IGF1R, IGF2, IL1A, IL1B, INCENP, ING2, INS, KDR, KIF25, KPNB1, MAD2L1, MKI67, PPP1R12A, SEPT2, NUMA1, NUP88, OPA1, PARK2, CHMP1A, PDE3A, PPP2R1A, PPP5C, PRKAR1A, RAD1, PEX19, RAD51, RAD51B, RAD51D, RAN, RB1, RBBP8, RPL24, RPS3, RPS6KA2, CLIP1, SMARCA4, AURKA, DYNLT3, DYNLT1, TOP2A, UBB, UBE2D1, VRK1, WEE1, XRCC2, ZNF207, NUP214, CLTCL1, USP9X, SMC1A, CUL3, FKBP6, CDC14A, CDK13, TNKS, BECN1, CDC23, RAB11A, PEX11A, CDC16, RNF8, LATS1, SMC3, CCNB2, CTDP1, ARHGEF2, ZW10, BUB3, AURKB, KIF3B, RECQL5, BRE, MAD2L1BP, CEP57, KNTC1, DLGAP5, CKAP5, CUL7, KIAA0196, DCLRE1A, ACOT8, TOM1L1, SMC4, ACTR2, RAD50, AKAP8, STAG1, KATNB1, ANAPC10, TUBGCP3, MAD2L2, SSSCA1, USP16, RGS14, STAG3, STAG2, PTTG2, ARPP19, JTB, TXNL4A, PIM2, PAPD7, UBE2C, CIT, ZWINT, CHEK2, DCTN3, PHB2, OIP5 |
2307 | GO:0044255 | 0.03 | 1.25 | 137.27 | 155 | 332 | cellular lipid metabolic process | ABCA1, ABCA4, ACAT1, ACHE, ADH5, ALAS1, ALDH1A1, ALDH1A3, ALDH3A2, ANG, ARF1, ARSA, STS, ARSD, ARSE, ARSF, ATM, BAX, OPN1SW, SLC25A20, CAT, CAV3, CCNC, CD36, CDC42, CETP, AKR1C4, CHKA, CHKB, CLPS, CSNK1G2, CTGF, CYP3A4, DBI, DPAGT1, EPHA8, ESR1, FDFT1, FDPS, GPC4, FGF7, FGFR3, GPC5, FGR, FLT1, FLT3, KDSR, G6PC, B4GALNT1, GATA6, OPN1MW, GK2, GPC3, GLB1, GMDS, GPC1, GPD1, GPD2, HEXA, HMGCL, HMGCR, HMGCS1, HMGCS2, HTR2C, IL1B, IMPA1, IMPA2, INPP1, INPP4A, INPPL1, KIT, LCAT, OCRL, OXCT1, P2RX7, PCK1, PCYT1A, PDE3A, PIGC, PIK3C2A, PIK3C2B, PIK3C3, PIK3CB, PI4KA, PI4KB, PIP4K2A, PPP2R1A, PRKD1, RAC1, RBP1, RBP2, OPN1LW, RLBP1, RXRA, CCL21, SDC1, SDC2, SDC4, SFTPB, ST6GAL1, SLC12A1, SLC25A1, SMARCD3, SMPD2, UAP1, SRD5A1, STAR, SULT2A1, TAZ, TBL1X, UGT8, ZP3, LRP8, PIP5K1B, SOAT2, NSMAF, PIK3R3, DGKE, AGPS, DGAT1, B4GALT4, PEX11A, INPP4B, HDAC3, ALDH1A2, SYNJ1, CPNE1, VAPB, VAPA, DHRS3, KLF4, CPNE6, GGPS1, PIGL, GAL3ST1, MPDU1, ABCG1, SDC3, RUBCN, PTDSS1, IP6K1, FIG4, GNE, PIGK, GPC6, COL4A3BP, DHRS9, CEPT1, ST3GAL6, VAV3, CARM1, AGPAT2, SLC35A1, CERS1, SERINC3 |
2308 | GO:0043687 | 0.04 | 1.25 | 115.18 | 130 | 276 | post-translational protein modification | BIRC5, AREG, ARF4, ARSA, STS, ARSD, ARSE, ARSF, BGLAP, BMI1, BRCA1, CD59, CDKN2A, CGA, COPA, COPB1, CSNK1D, CTSZ, DAD1, CD55, DHPS, DYNC1H1, DYNC1I1, DYNC1I2, DPAGT1, PHC1, PHC2, EEF2, EIF5A, F7, F10, FUT8, GALNT1, GAS6, GGCX, B4GALT1, GLB1, GMDS, GOLGA2, GOLGB1, GRIA1, INCENP, INS, STT3A, LMAN1, MGAT2, MGAT5, NUP88, NUP98, CFP, PIGC, PPP6C, PRKCSH, PROC, PROS1, RAB1A, RANBP2, RNF2, RPN2, SEL1L, ST6GAL1, SUMO3, SP3, SP100, UAP1, SPTA1, SPTB, AURKA, TRAPPC10, TOP1, TOP2A, SUMO1, WRN, XPC, XRCC4, TUSC3, NUP214, AAAS, SMC1A, CBX4, USO1, DYNLL1, GALNT4, B4GALT4, B4GALT3, PROZ, HERC2, SMC3, AURKB, COPB2, B4GALT6, B4GALT5, COG1, ATG5, PIGL, GOSR1, SEC22B, GOSR2, NUP155, NUP93, GNE, PIGK, UBA2, PREB, CHST4, STAG1, B3GNT3, PIAS3, ST3GAL6, SPON1, SEC24B, COG5, SEC23A, CRTAP, ATG7, SLC35A1, DCTN6, STAG2, NUP50, SEC24A, KDELR1, OS9, TMED10, TMEM115, ADAMTS13, ADAMTS5, NUPL2, ADAMTS7, DCTN3, COPE |
2309 | GO:0044238 | 0.00 | 1.25 | 305.43 | 341 | 860 | primary metabolic process | ABCA4, ACAA1, ACADM, ACADS, ACAT2, ACLY, ACOX1, ADA, ADK, ADSL, AK2, AK4, ALAS1, ABCD1, ALDH1A1, ALDH1A3, ALDH3B2, ALDH3A2, ALOX15B, AMPD1, AMPD2, AOX1, APOF, APRT, ATP1A2, ATP2B2, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1A, ATP6V1B1, ATP6V1B2, ATP5O, AZGP1, BICD1, BYSL, DAGLA, CACNB4, ENTPD2, CFTR, AKR1C4, CHKA, CHKB, CLNS1A, CLPS, CNP, COX4I1, COX5B, COX6A1, COX6B1, COX7B, COX7C, COX8A, COX15, CPT1B, CPT2, CSTF3, CYP1A2, CYP2A6, CYP2A13, CYP2F1, CYP3A4, CYP3A5, CYP8B1, CYP11B1, CYP24A1, CYP51A1, DBI, DHX8, DHX9, DDX10, DECR1, DFFB, DHODH, DNASE1L1, DNASE1L2, DNASE1L3, DNASE2, TRDMT1, DNTT, DTYMK, DUT, TYMP, ECH1, EDN2, SLC29A1, ERCC5, ETFA, ETFDH, FAAH, FABP2, FABP6, FABP7, FANCA, FANCC, FANCD2, FANCE, ACSL4, FANCG, FDFT1, FDPS, FDXR, FEN1, KDSR, GPX2, GRSF1, GTF3C1, GTF3C2, GUCY1B3, GUK1, HADHA, HMGCS1, HMGCS2, HPGD, HSD11B1, HSD17B3, HSD17B4, IL1RN, IMPDH1, IMPDH2, INPP4A, ISG20, KCNQ1, KPNB1, LIPA, FADS3, MGST2, MKI67, NUDT1, DRG1, NTHL1, OCRL, ORC5, OXCT1, PAFAH1B2, PAFAH1B3, PAFAH2, PCCA, PCYT1A, PDC, PDE3A, PDE4A, PDE4B, PDE4C, PDE7A, ENPP3, PIK3C2A, PIK3C2B, PI4KA, PI4KB, PIP4K2A, EXOSC9, PRIM1, PRIM2, PRPS2, PRPSAP1, PTGDR, PTGS1, PTMA, RAD1, ABCD3, RAD51B, RAD51D, RBMS1, RBP1, RBP2, REV3L, RFC2, RFC3, RFC4, RFC5, RHEB, RLBP1, RNASE1, RNASE2, RNASE3, RNASE6, ABCE1, RP9, RPA3, RRM1, ACSM3, SRSF1, SRSF3, SRSF5, SLC10A1, SLC10A2, SLC12A1, SLC16A1, SLCO1A2, SNRPA, SNRPA1, SNRPC, SNRPD1, SNRPD2, SNRPE, SNRPF, SNRPN, SQLE, SRD5A1, SULT1E1, ELOVL4, SULT1A1, SULT1C2, SULT2B1, SULT2A1, SURF1, TAZ, PRDX2, TPMT, TSN, TYRP1, U2AF1, UPP1, UQCRB, UQCRH, TRPV1, XPA, XRCC2, YWHAZ, SF3A2, RBM10, ACOX2, ACOX3, PIP5K1B, SOAT2, KCNAB2, DGKE, CYP4F2, AGPS, PRPF18, RRP1, HSD17B6, RNASET2, DGAT1, ABCC3, PEX11A, BANF1, INPP4B, ALDH1A2, SGPL1, MBD4, CH25H, PRPF3, EXO1, COX7A2L, SCAF11, DDX21, VAPA, DHRS3, GTF3C5, GTF3C3, EFTUD2, CPNE6, COX5A, RECQL4, SNRNP40, FADS2, GGPS1, TP53I3, ATP5J2, CHD1L, ENTPD4, PRDX6, KIAA0391, UTP14C, KIAA0101, SNX17, DHX38, IP6K1, GINS1, DDX46, SMG7, FIG4, PAN2, DCLRE1A, EXOG, G3BP1, SUGP2, DHRS9, DHRS2, DDX39A, SMNDC1, CCNO, CEPT1, NSA2, EMG1, ACAA2, ECI2, ATP5H, CHERP, RNASEH2A, AGPAT2, RPP30, RPP38, SLCO1B1, TBL3, IVNS1ABP, PDPN, ATP5L, SPHAR, RRAGA, EBP, UTP14A, FAXDC2, PDE10A, DHRS4, TXNL4A, SMPDL3A, DBF4, SRSF8, SF3A3, ACOT2, SF3B2, SLC27A5, SLC27A4, SLC27A2, SNRNP27, PAPD7, CPSF6, DUS4L, HSF2BP, RPP14, KRR1, CLASRP, C14orf1, NUDT3, WDHD1, WBP4, XPOT, DDX19B, TREX1, DDX42, ACOT7, EXOSC8 |
2310 | GO:0007264 | 0.04 | 1.24 | 126.55 | 142 | 308 | small GTPase mediated signal transduction | A2M, ACTB, ACTG1, BIRC5, KLK3, ARF1, ARF4, ARL4D, ARF5, RND3, RHOH, ARL1, ARL2, BUB1, BUB1B, KRIT1, CDC20, CDC25C, CDC42, CDH1, CENPA, CENPE, CENPF, CFTR, CHN1, CHN2, CTNNA1, CYBA, DIAPH1, DIAPH2, CTTN, FLNA, CENPI, GDI2, GEM, SFN, H3F3B, INCENP, KIF5A, KLK2, KLC1, MAD2L1, RAB8A, MEN1, PPP1R12A, PPP1R12B, NUP98, OCRL, OPHN1, PDPK1, PIK3C3, RELN, RAB1A, RAB3A, RAB3B, RAB4A, RAB6A, RAB13, RAB27A, RAB27B, RABIF, RAB5C, RAC2, RAC3, RAN, RANBP2, RAP1GAP, RAP1GDS1, RHEB, RPS27, CLIP1, SIAH2, SIPA1, SRF, TSC2, YWHAG, YWHAH, YWHAZ, RAB7A, RND2, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, BCAR3, RAB11A, IQGAP1, HIST1H3F, PRC1, DIRAS3, ZW10, BUB3, AURKB, RAB11B, TRIP10, SLIT2, RAB33A, RAB9A, RAB3D, RAB36, KNTC1, RAPGEF5, CKAP5, RHOBTB1, ARHGAP25, ABI1, SH2D3C, SH2D3A, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR2, ARPC2, ARL4C, ARL4A, ARFRP1, TNK2, BAIAP2, ARPC1A, RASL10A, RAB40B, RAB32, IFT27, RAB35, RAB31, RAPGEF4, CIT, ZWINT, RABL2B, RABL2A |
2311 | GO:0055114 | 0.04 | 1.23 | 137.89 | 154 | 336 | oxidation-reduction process | ADH1B, ADH5, ALDH1A1, ALDH2, ALDH3A1, ALDH1B1, ALDH1A3, ALDH3B2, ALDH9A1, ALDH3A2, ALDOB, ALDOC, ALOX15B, AOC2, AOX1, APOA1, APOA4, ALDH7A1, BCKDHA, BLVRA, BLVRB, CBS, CDO1, AKR1C4, CP, CPOX, CRYM, CRYZ, SLC25A10, CYBA, CYP2A6, CYP2A13, CYP2F1, CYP3A4, CYP3A5, CYP8B1, CYP11B1, CYP24A1, CYP27B1, CYP51A1, DAO, DBH, DHCR7, DHCR24, DHFR, DHODH, CYB5R3, DIO1, DIO2, DIO3, SARDH, DPYD, ENO2, FDFT1, FDXR, FMO3, KDSR, GAPDH, GDI1, GDI2, GFER, GLUD1, GLUD2, GPD2, GPX1, GPX2, GPX3, GPX7, HSD17B10, HCCS, HK2, HMGCR, HPD, HPGD, HSD11B1, HSD17B3, IMPDH1, IMPDH2, IDO1, LDHC, FADS3, MGST2, ALDH6A1, P4HA1, PAH, PAM, PAX2, PFKFB2, PFKFB4, PGAM2, PGD, PGK1, PHF2, PTGIS, PTGS1, PYCR1, ALDH18A1, QDPR, RRM1, RRM2, SOD1, SOD2, SORD, SQLE, SRD5A1, SUOX, PRDX2, TST, TYRP1, UGDH, KDM6A, PXDN, COIL, KDM5C, KDM5D, EPX, BBOX1, KCNAB2, DDO, CYP4F2, AGPS, PIR, HSD17B6, AOC3, AKR1C3, ALDH4A1, CREG1, ALDH1A2, P4HA2, CH25H, AIFM1, DHRS3, GRHPR, FADS2, GSTO1, TP53I3, PRDX6, KDM4A, HEPH, AASS, DHRS9, DHRS2, ABCC4, AKR1A1, IFI30, ENOX2, PRDX4, FAXDC2, ALDH1L1, DHRS4, PRDX3, PDIA5, DUS4L, CYB561D2 |
2312 | GO:0051171 | 0.00 | 1.22 | 526.92 | 581 | 1316 | regulation of nitrogen compound metabolic process | ABCA1, ABCA2, ACTN4, ACTL6A, ACTN1, ACVR1, ACVR1B, ACVR2A, ADCY7, ADCYAP1R1, ADORA2A, ADRB2, AGTR2, ALK, ALX3, ANXA3, APBB1, XIAP, AREG, ARF4, RHOH, PHOX2A, ARNT, ASS1, ATOH1, AVP, AVPR2, BAX, BCL9, BMP1, BMP8B, BMPR1A, BRDT, ZFP36L2, KLF9, BTF3, BTG1, BTK, CALCR, CALM3, CAMK4, CAMK2A, CBFB, CBL, CCNB1, CCNC, CCNE1, CCNH, CCNT2, CD3D, CD80, CD86, TNFSF8, CD40, CDC5L, CDC42, CDH1, CDK8, CDKN1A, CDX1, CEBPE, CENPB, CGA, CHD1, CHD2, CHD3, CHUK, CLK3, COL1A1, CREBL2, CRX, CSF2, CSNK2A1, CSNK2A2, CTH, CTNND1, CTNND2, DGKQ, DCN, DHFR, DLX3, DLX5, DLX6, DNM2, ARID3A, RCAN1, DTX1, E2F2, E2F4, E2F5, EBF1, ECM1, EDA, S1PR1, CELSR2, EGR2, EGR3, EGR4, ELAVL2, ELF1, ELK1, EMX1, EMX2, EPHA5, EYA4, ERCC3, ERCC6, ERG, ERN1, ESRRG, ETS1, ETV1, ETV2, ETV4, ETV5, EVX1, EWSR1, EYA1, EYA2, EYA3, EZH1, F2R, F2RL1, FBN1, EFEMP1, FGF1, FGF7, FGF8, FGFR4, FLI1, FLII, AFF2, FSHR, NR5A1, GATA4, GCG, KAT2A, GDF9, GDNF, GHRH, GHRHR, GPC3, GLP1R, GNAL, GNAS, GPD1, GSC2, GTF2F1, GTF2I, GTF3A, BRF1, GUCA1A, GUCA1B, GUCA2A, GUCA2B, HAS3, HCK, HEXB, HGF, HIP1, HIVEP2, HLF, HLX, HMGN1, NR4A1, HMX2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD3, HOXD4, HOXD11, PRMT1, HSP90AA1, HSP90AB1, ICAM1, SP110, IGF2, IHH, IL1A, FOXK2, ILK, ING2, INSIG1, INSL3, ITGA6, IRF5, ITGA3, JUP, KIT, KPNA1, KRAS, AFF3, ABLIM1, LTF, LUM, EPCAM, SMAD6, MAZ, MEIS1, MEOX2, KITLG, MGMT, ATXN3, AFF1, FOXO4, PPP1R12A, NRF1, NRL, NTF3, NTRK1, NTRK2, NTRK3, DDR2, NVL, OAS1, OAS3, SIX6, ORC1, OTX1, OTX2, P2RX4, P2RX7, P2RY1, P2RY11, PCSK6, SERPINE1, PAM, PAX1, PCK1, PDE4D, PDE8A, PDPK1, PF4, PFDN1, PFN1, PGR, PPP1R8, PPP2R1A, PPP4C, PPP3R1, PRKAR1A, PRKCB, PRKCG, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK8, RELN, PTPN1, PTPN14, RAC1, RAD51, RAF1, RBBP4, RBBP6, RBL2, RCVRN, DPF2, RFC1, RFX2, RFX4, RFXAP, RNF6, RPL6, RRM2, RXRG, RYR2, S100A8, S100A12, SAFB, ATXN7, SETMAR, TRA2B, SGK1, SHC1, SLC9A1, SLC11A1, SMARCA1, SMARCC1, SMARCD3, SNAPC1, SNAPC2, SNAPC3, SNAPC4, SNRNP70, SOD2, SON, SOX1, SOX12, SP1, SP2, SP4, SPIB, SRPK2, SSRP1, STAT2, STAT4, STAT5B, SUPV3L1, SYK, TAF2, TAF4B, TAF5, TAF6, TAF13, TARBP1, HNF1A, ZNF354A, TMF1, TMPO, TNNI2, TOP2A, NR2C2, TRAF1, TRAF2, CCT3, TRIP6, TSC2, TULP3, TYMS, UBE2D2, UBE2L3, UBE2V1, UBE2V2, UBE3A, UCP1, UNG, USF1, USF2, VAV1, VIP, VIPR2, TRPV1, WNT1, WNT2, YWHAH, ZFP37, ZFPL1, ZFX, ZIC1, ZNF3, ZNF711, ZNF7, CNBP, ZNF14, ZNF708, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF80, ZNF84, ZNF221, ZNF90, ZNF124, ZNF132, ZNF133, ZNF134, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, TRIM25, ZBTB17, ZNF155, VEZF1, ZNF165, ZNF180, ZNF207, ZNF214, ZNF223, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, ZXDA, PRDM2, CSDE1, FZD5, BRPF1, MAFK, ARHGEF5, ZNF212, BRD3, CSRP3, FOSL1, FGF23, ANP32A, ZNF239, DPF1, CHAF1B, USP9Y, FZD4, FZD7, UTF1, CUL4A, CUL2, FOXN1, TTF2, OGT, ITGA8, IKBKG, IKBKAP, CAMK1, PIR, BLZF1, KHSRP, STK16, TNFSF11, KLF7, CDK13, RFXANK, CHRD, PDE5A, DYNLL1, TRADD, EDF1, RIPK1, TNFSF13, RIPK2, CFLAR, TSC22D1, KAT2B, BUD31, CPNE1, BCL10, PHOX2B, FUBP3, USP13, RPS6KA4, TNFSF18, BAZ1B, AIP, PDLIM1, AIFM1, DYRK1B, CTDP1, ARHGEF2, BMP15, VAPB, CCPG1, ITGB1BP1, ZNF235, TRIP11, HMGN3, TRIP4, CER1, CIAO1, ZRANB2, FHL5, IL27RA, ONECUT2, LITAF, TBPL1, GTPBP1, BRE, SOX13, RBM39, CREB5, WTAP, ABCG1, GUCA1C, ZNF516, SAFB2, VGLL4, BZW1, ZNF646, USP34, SETD1A, ZFYVE16, SERTAD2, TSC22D2, RB1CC1, ZBTB24, ZNF518A, SUPT7L, RNF10, ZBTB5, RBX1, DMTF1, SRA1, PARP3, PQBP1, TSFM, PREB, CEBPZ, ZNF197, ALYREF, RNF41, CALCRL, ZNF443, DENND4A, SF3B4, IRX5, RAMP2, FSTL3, STAG1, APBB3, TNIP1, PCGF3, HMG20B, KLF2, PIAS3, RAPGEF3, RBM14, PPIE, SLC30A9, TRIM38, CAP2, CAP1, CREB3, CARM1, ZNF211, BATF, CCT7, CCT4, CCT2, ERLIN1, ARID3B, TRIM16, TAF6L, RAD51AP1, RGS14, DMRT2, KLF1, CCT8, TBR1, SIX2, RAI1, PTTG2, PHTF1, AHCYL1, ZBTB6, ZNF266, ZNF275, SRCAP, RUVBL2, MALT1, CPSF4, BRD8, PAPOLA, PRDX3, ASCC3, SLC38A3, RBPMS, PIM2, SOX30, WDR5, PRDM7, ERLIN2, SOX21, PSIP1, ZNF277, SUPT16H, SP140, SNF8, KLF8, ECD |
2313 | GO:0044267 | 0.00 | 1.20 | 565.82 | 618 | 1440 | cellular protein metabolic process | ABCA1, ABO, ACADVL, ACP1, ACP2, ACTB, ACTL6A, ADAM10, ADD1, ADH5, ADORA2A, ADPRH, PARP4, ADRBK1, ADRBK2, AGXT, AMHR2, ANPEP, SLC25A4, ANXA1, APBB1, APCS, APOA4, KLK3, AREG, ARF4, ARNTL, ARSA, STS, ARSD, ARSE, ARSF, ART1, ASL, ASNA1, ASNS, ATR, AXL, BACH1, BARD1, BCHE, OPN1SW, BGLAP, BHMT, BLK, BMX, BNIP3, BNIP3L, BRCA2, BTG1, BTK, SLC25A20, CAMK4, CBFB, CBL, CBLB, CCIN, CDK3, CDK6, CDK8, CGA, CHRM1, CHRM3, CHUK, TBCB, CLK3, TPP1, CLN5, CCR5, COL3A1, COPA, COPB1, CPA3, ATF2, CSNK1G2, CSNK1G3, SLC25A10, CTH, CTSG, CTSK, CTSV, CTSS, CTSZ, CYLD, DAD1, DARS, DCX, DDB1, DDB2, DDX11, DHPS, DMBT1, DYNC1H1, DYNC1I1, DYNC1I2, DPAGT1, DSP, DTX1, E4F1, PHC1, PHC2, EEF1A2, EEF1B2, EGR2, EHHADH, EIF1AX, EIF2S3, ELK1, ENPEP, EPB42, EPHA3, EPHA5, EPHB2, EPHB3, EYA4, ERCC3, ERG, EXT1, EXT2, EXTL1, EXTL3, EYA1, EYA2, EYA3, EZH1, F7, F10, FAP, FAU, EFEMP1, FKBP3, FKBP5, FRK, FUT6, FUT8, FYB, GAD1, GAK, B4GALNT1, GALNT1, GARS, GATA6, BLOC1S1, OPN1MW, GFER, GGCX, B4GALT1, GIP, GLB1, GMDS, GOLGB1, GRK6, GRIA1, GUCY2C, GUCY2F, GUCY2D, H3F3B, HARS, HCK, HDGF, HEXB, HLCS, HMBS, PRMT2, HSPA9, IAPP, IGFBP2, IGFBP6, IL12RB2, INCENP, INSRR, ITGAV, STT3A, IVL, KCNE1, LIMK2, LIPE, LMAN1, MAN2B1, DNAJB9, MDH2, MFGE8, MGAT2, MGAT5, ATXN3, RPL10A, CNOT4, NRTN, NUP88, NUP98, OAS2, P4HA1, PAH, PAM, PAPPA, PCK1, PCMT1, PCSK1, PCSK5, CDK16, PDK4, PEX12, CFP, PFDN1, PFDN2, PGA5, PGGT1B, PHEX, PHF2, PHKA2, PHKG1, PIGC, PIK3C3, PPIB, PPIC, PPID, PPM1A, PPM1B, PPM1G, PPP1R3C, PPP2CB, PPP4C, PPP3R1, PPP6C, PPT1, PRKCB, PRKCI, PRKCQ, PRKCSH, PRKG1, PRKX, PROC, PSKH1, PTK7, PTPN4, PTPN7, PTPN12, PTPN13, PTPN14, PTPRB, PTPRD, PTPRE, PTPRH, PTPRM, PTPRN, PTPRN2, QARS, RAB1A, RAB3B, RAB6A, RAB27A, RABGGTA, RABGGTB, RAG2, RANBP2, ARID4A, RBBP6, OPN1LW, RGR, RNF2, RNF6, RPL3L, RPL4, RPL6, RPL7, RPL7A, RPL10, RPL11, RPL13, RPL22, RPL23A, RPL24, RPL26, RPL30, RPL28, RPL29, RPL31, RPL32, RPL34, RPL35A, RPL36AL, RPL37, RPL37A, RPL39, RPL36A, RPN2, RPS2, RPS3A, RPS4Y1, RPS6, RPS6KA2, RPS7, RPS11, RPS16, RPS19, RPS20, RPS23, RPS25, RPS26, RPS27, RPS28, RPS29, SALL1, SATB1, SBF1, ATXN7, SEL1L, SETMAR, SFPQ, SFTPB, SFTPD, SGK1, SHMT2, SIAH1, ST6GAL1, SLC34A1, SLC25A1, SOX11, SP3, SP100, UAP1, SPRR1B, SPRR2A, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3, SRMS, SRP14, SRP19, SRP68, SRPK2, SSR1, SSR3, STAT4, CDKL5, SULT1A3, SUV39H1, TAF5, TARS, TBCA, TBCD, TBCE, TBL1X, TRAPPC10, TOP1, TOP2A, TPTE, NR2C2, CCT3, TRIO, TSHB, TTC3, TTF1, TUBA4A, TUBA3C, TUFM, TYK2, TYRO3, UBA7, UBE2D2, UBE2E2, UBE2H, UBE2V1, UBE2V2, UCP1, UFD1L, KDM6A, VBP1, VRK1, WEE1, WHSC1, WRN, XPC, XRCC4, TRIM25, ZBTB17, PRDM2, PTP4A1, RNF103, TUBA1A, SCG2, BRPF1, RAB7A, EPM2A, TUSC3, NUP214, SLC25A16, CUL5, AAAS, GAN, CLPP, USP11, USP9X, KDM5C, SMC1A, UBL4A, KDM5D, USP9Y, HIST1H4I, BAP1, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, DYRK2, CUL4B, CUL4A, CUL2, TPST2, TPST1, FKBP6, CDC42BPA, PPM1D, HAT1, COPS3, CBX4, CDC14A, DENR, STK16, USO1, CDK13, DDX3Y, DYNLL1, TNKS, GALNT4, B4GALT4, B4GALT3, B3GALT2, TNK1, CTSF, RNGTT, RIOK3, DYRK4, TRIM24, CDKL1, DCAF5, PROZ, EIF2S2, HERC2, HIST1H3F, P4HA2, USP13, KALRN, SLC25A14, RNF8, BAZ1B, UBA3, RPL14, EIF1AY, USP6, USP2, ATP6V0D1, SMC3, DYRK1B, CTDP1, DCLK1, AURKB, STK17B, STK17A, COPB2, GTF3C4, B4GALT6, B4GALT5, RPL23, UBE4A, COG1, ARHGEF6, PICK1, PIGL, GAL3ST1, GOSR1, RAB3D, SEC22B, GTPBP1, GOSR2, NR1D1, CLOCK, BRE, CDC42BPB, RNF7, AATK, SNCAIP, NUP155, TTLL4, DZIP3, NUP93, UBE3C, VPRBP, USP34, SETD1A, SPCS2, TOMM20, SPOCK2, CUL7, DNAJC6, SETDB1, AREL1, SUPT7L, RNF10, USP3, NR1H4, PDCD6IP, GNE, PIGK, PARP2, PARP3, SH2D3C, SH2D3A, UBA2, PTPRU, COL4A3BP, TSFM, SGK2, PREB, PDIA6, ABI2, TRIM28, CHST4, SLC25A13, SLC25A15, STAG1, CWC27, SPEG, TRAIP, BCKDK, MARCH6, B3GNT3, TRIM22, TUBA1B, ST3GAL6, SPON1, UBAC1, SEC24B, RBM14, PPIE, TOMM40, PPIH, COG5, TRIM38, UBE2E3, SLC25A17, SEC23A, CARM1, PRDX4, SLC35A1, SLC34A2, CCT7, CCT4, CCT2, ERN2, TRIM3, ERLIN1, RBCK1, STAMBP, TRIM16, TAF6L, EXOC5, FARS2, DCTN6, FUT9, RRH, CCT8, USP39, YME1L1, STAG2, NUP50, SEC24A, SRCAP, BRD8, KDELR1, SEC61B, PDIA5, OS9, RAB40B, CKAP4, TMED10, COPS6, KDELR3, PIM2, WWP1, WWP2, TMEM115, WDR5, ADAMTS13, ADAMTS5, NUPL2, PTPN21, ATE1, PRDM7, CIT, WDR45, FICD, ERLIN2, ADAMTS7, BAZ2A, RPL35, SEC63, RNF24, DCTN3, DUSP12, SNF8, USP18, B4GALT7, LYPLA2, COPE, FKBP9 |
2314 | GO:0044237 | 0.02 | 1.20 | 248.25 | 273 | 718 | cellular metabolic process | ABO, ACP1, ACP2, ACTB, ACYP1, ACYP2, ADAM10, ADD1, ADPRH, ADRBK1, ADRBK2, ALB, ALPI, ALPP, ALPPL2, AMHR2, KLK3, ARL1, ARR3, ART1, ASGR2, ASNA1, AXL, BLK, BMX, BSG, CA1, CA2, CA4, CA5A, CA6, CA7, CAMLG, CBLB, CCIN, CD9, CDK3, CDK6, CHRM1, TBCB, CKS1B, CLTC, CCR5, COL2A1, COL3A1, COL11A1, COPA, COPB1, CSNK1G3, DAD1, DGKA, DGKB, DCX, CYB5R3, DMBT1, DNM1, DYNC1H1, DYNC1I1, DYNC1I2, DSP, PHC1, PHC2, EPHA2, ENSA, EPB42, EPHA3, EPHB1, EPHB2, EPHB3, FCER1G, FKBP3, FKBP5, FUT6, FYB, GAK, GALNT1, GFER, GGCX, GIP, GOLGB1, FFAR3, GRK6, GRIA1, HRC, HSD17B3, HSPA9, IAPP, IGFBP2, IGFBP6, IL12RB2, INCENP, INSRR, STT3A, ITPKB, IVL, KCNE1, LIMK2, LMAN1, MAN2B1, MFGE8, MGAT2, MGAT5, NRTN, PAPPA, PCMT1, CDK16, PEPD, PEX12, CFP, PFDN2, PGA5, PGGT1B, PHEX, PPIB, PPIC, PPM1B, PPM1G, PPP2R1B, PPP6C, PRG2, PRKCSH, PRKG1, PRKX, PSKH1, PTK7, PTPN4, PTPN7, PTPN12, PTPN13, PTPRB, PTPRD, PTPRE, PTPRH, PTPRM, PTPRN, PTPRN2, RAB3B, RAB6A, RABGGTA, RABGGTB, RGR, RPS6KA2, RRAS, SBF1, SEPP1, SGSH, SLC2A3, SLC6A6, SLC7A4, SLC10A1, SLC10A2, SLC16A1, SLC20A1, SLCO1A2, SLC22A2, SPRR1B, SPRR2A, SPRR2D, SPRR2E, SPRR2F, SPRR2G, SPRR3, SRMS, CDKL5, STYX, TBCA, TBCD, TBCE, TRAPPC10, TPTE, TRIO, TUBA4A, TUBA3C, TYK2, TYRO3, UBE2E2, UGT2B7, KDM6A, VBP1, VRK1, WEE1, PTP4A1, TUBA1A, SCG2, TUSC3, SLC7A5, UBL4A, KDM5D, CDC42BPA, PPM1D, CDC14A, USO1, HSD17B6, GALNT4, B3GALT2, TNK1, ABCC3, RIOK3, DYRK4, CDKL1, DCAF5, KALRN, ATP6V0D1, DGKI, DCLK1, RAB11B, STK17B, COPB2, COG1, ARHGEF6, GOSR1, RAB3D, SEC22B, MINPP1, GOSR2, CDC42BPB, AATK, TTLL4, TOMM20, DNAJC6, NUAK1, FAM20B, SH2D3C, SH2D3A, UBA2, PTPRU, SGK2, FEM1B, PDIA6, ABI2, DHRS2, SPEG, TRAIP, TUBA1B, SPON1, UBAC1, SEC24B, ZER1, TOMM40, COG5, UBE2E3, SEC23A, ARFGEF2, SLC34A2, SLCO1B1, TRIM3, STAMBP, EXOC5, DCTN6, FUT9, RRH, SEC24A, DHRS4, UGT2A1, KDELR1, PDIA5, RAB40B, CKAP4, KDELR3, RAB31, TMEM115, ADAMTS5, PTPN21, CIT, CDC37, WDR45, FICD, AKAP13, SEC63, CA5B, DCTN3, COPE, FKBP9 |
2315 | GO:2000112 | 0.01 | 1.16 | 542.11 | 582 | 1335 | regulation of cellular macromolecule biosynthetic process | AARS, ABCA2, ACO1, ACTL6A, ACVR1, ACVR1B, ACVR2A, ADRB2, AGTR2, AKT2, ALK, ALX3, ANXA3, APBB1, XIAP, AREG, ARF4, RHOH, PHOX2A, ARNT, ATM, ATOH1, BCL9, BMP1, BMP8B, BMPR1A, BRDT, ZFP36L2, KLF9, BTF3, BTG1, BTK, CAMK4, CAMK2A, CBFB, CBL, CCNC, CCNE1, CCNH, CCNT1, CCNT2, CD3D, CD28, CD80, CD86, TNFSF8, CD40, CDC5L, CDC42, CDH1, CDK4, CDK8, CDK9, CDKN1A, CDX1, CEBPE, CENPB, CGA, CHD1, CHD2, CHD3, CHUK, CLU, COL1A1, CREBL2, CRX, CSF2, CSNK2A1, CSNK2A2, CTH, CTNND1, CTNND2, DGKQ, DAZ1, DCN, DDX1, DDX6, DHFR, DIO2, DLX3, DLX5, DLX6, DNM2, ARID3A, RCAN1, E2F2, E2F4, E2F5, EBF1, ECM1, EDA, S1PR1, EEF2, CELSR2, EGR2, EGR3, EGR4, EIF2B1, EIF4A1, EIF4A2, EIF4B, EIF4G1, EIF4G2, EIF5, EIF5A, ELAVL2, ELAVL1, ELF1, ELK1, EMX1, EMX2, EPHA5, ERBB2, EYA4, ERCC3, ERCC6, ERG, ERN1, ESRRG, ETS1, ETV1, ETV2, ETV4, ETV5, EVX1, EWSR1, EYA1, EYA2, EYA3, EZH1, F2R, F2RL1, FBN1, EFEMP1, FECH, FGF1, FGF7, FGF8, FGFR4, FLI1, FLII, NR5A1, GALR1, GATA4, GCG, KAT2A, GDF9, GDNF, GPC3, GSC2, GTF2F1, GTF2I, GTF3A, BRF1, HAS3, HCK, HEXB, HGF, HIP1, HIVEP2, HLF, HLX, HMGN1, NR4A1, HMX2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD3, HOXD4, HOXD11, PRMT1, HSPB1, ICAM1, SP110, IGF2, IHH, IL1A, IL10, FOXK2, ILK, ING2, INS, INSIG1, ITGA6, IRF5, ITGA2, ITGA3, JUP, KIT, KRAS, AFF3, ABLIM1, LTF, LUM, EPCAM, SMAD6, MAZ, MEIS1, MEOX2, KITLG, ATXN3, AFF1, FOXO4, PPP1R12A, NRF1, NRL, NTF3, NTRK1, NTRK3, DDR2, NVL, OGG1, SIX6, ORC1, OTX1, OTX2, P2RY1, PCSK6, SERPINE1, PAM, PAX1, PCK1, PDE8A, PDPK1, PF4, PFDN1, PFN1, PGR, PPP1CA, PPP1R8, PPP2R1A, PPP3R1, PRKAA1, PRKAR1A, PRKCB, PRKCI, PRKD1, PRKCQ, PRKCZ, MAPK3, MAPK8, DNAJC3, RELN, PSMA6, PSMC1, PSMC3, PSMC4, PTAFR, PTPN14, RAC1, RAF1, RBBP4, RBBP6, RBL2, DPF2, RFC1, RFX2, RFX4, RFXAP, RGS2, RNF6, RPL6, RPL38, RPS4X, RPS6KA1, RPS6KA3, RPS6KB2, RRM2, RXRG, RYR2, S100A8, S100A9, S100A12, SAFB, ATXN7, SFSWAP, SGK1, SHC1, SLC9A1, SLC11A1, SMARCA1, SMARCC1, SMARCD3, SNAPC1, SNAPC2, SNAPC3, SNAPC4, SOD2, SOX1, SOX4, SOX12, SP1, SP2, SP4, SPIB, SSRP1, STAT2, STAT4, STAT5B, SYK, TAF2, TAF4B, TAF5, TAF6, TAF13, TARBP1, HNF1A, ZNF354A, TMF1, TMPO, TNFRSF1A, TNNI2, TOP2A, NR2C2, TRAF1, TRAF2, CCT3, TRIP6, TSC2, TULP3, TYMS, UBE2D2, UBE2L3, UBE2V1, UBE3A, UCN, UCP1, USF1, USF2, VAV1, EIF4H, WNT1, WNT2, YWHAH, ZFP37, ZFPL1, ZFX, ZIC1, ZNF3, ZNF711, ZNF7, CNBP, ZNF14, ZNF708, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF26, ZNF28, ZSCAN20, ZNF32, ZNF33A, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF69, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF80, ZNF84, ZNF221, ZNF90, ZNF124, ZNF132, ZNF133, ZNF134, ZNF138, ZNF140, ZNF141, ZNF142, ZNF143, ZNF146, TRIM25, ZBTB17, ZNF155, VEZF1, ZNF165, ZNF180, ZNF207, ZNF214, ZNF223, ZNF225, ZNF227, ZNF229, ZNF230, ZNF232, ZXDA, PRDM2, CSDE1, PAX8, FZD5, BRPF1, MAFK, ARHGEF5, ZNF212, BRD3, CSRP3, FOSL1, FGF23, ANP32A, ZNF239, DPF1, CHAF1B, USP9Y, PICALM, FZD4, FZD7, UTF1, DYRK2, CUL2, FOXN1, TTF2, OGT, ITGA8, IKBKG, IKBKAP, CAMK1, PIR, BLZF1, MAPKAPK5, KHSRP, STK16, TNFSF11, KLF7, CDK13, RFXANK, CHRD, DYNLL1, TNKS, EIF3A, EIF3B, EIF3D, EIF3F, EIF3G, EIF3J, TRADD, EDF1, RIPK1, RIPK2, CREG1, CFLAR, TSC22D1, CDC123, EIF2B2, BUD31, CPNE1, BCL10, PHOX2B, FUBP3, USP13, RPS6KA4, TNFSF18, BAZ1B, PDLIM1, DYRK1B, CTDP1, ARHGEF2, BMP15, CCPG1, ITGB1BP1, ZNF235, HMGN3, TRIP4, CER1, CIAO1, ZRANB2, FHL5, ONECUT2, LITAF, TBPL1, SOX13, RBM39, CREB5, ABCG1, ZNF516, SAFB2, EIF5B, VGLL4, BZW1, ZNF646, USP34, SETD1A, ZFYVE16, SERTAD2, CTIF, TSC22D2, RB1CC1, ZBTB24, ZNF518A, EPM2AIP1, SUPT7L, RNF10, ZBTB5, RBX1, DMTF1, CASP8AP2, SRA1, PQBP1, TSFM, PREB, TRAP1, CEBPZ, ZNF197, ALYREF, RNF41, EIF1, ZNF443, DENND4A, IRX5, FSTL3, STAG1, SAP18, EIF1B, APBB3, TNIP1, PCGF3, TRIM22, HMG20B, KLF2, PIAS3, RAPGEF3, RBM14, PPIE, SLC30A9, TRIM38, EIF3M, CREB3, CARM1, ZNF211, BATF, CCT7, CCT4, CCT2, SORBS1, USP16, ERLIN1, ARID3B, TRIM16, TAF6L, RGS14, DMRT2, KLF1, CCT8, TBR1, SIX2, RAI1, PTTG2, PHTF1, SRSF10, ZBTB6, ZNF266, ZNF275, SRCAP, RUVBL2, MALT1, BRD8, PRDX3, ASCC3, SLC38A3, RBPMS, PIM2, SOX30, WDR5, PRDM7, ERLIN2, SOX21, PSIP1, ZNF277, SUPT16H, SP140, SNF8, KLF8, ECD |
2316 | GO:0034641 | 0.04 | 1.15 | 282.15 | 304 | 744 | cellular nitrogen compound metabolic process | ACADL, ACADSB, ACAT1, ADAR, ADARB1, PARP4, AGXT, AMBP, AMT, ANPEP, ANXA1, AREG, ASPA, ATM, ATR, AUH, AZGP1, BARD1, BAX, BCAT1, BCAT2, BCKDHA, BGLAP, BICD1, BLVRA, BLVRB, BTD, BYSL, CBS, CCNB1, ENTPD2, CDC25C, CDC42, CDO1, CLK3, TPP1, CLN5, CLNS1A, CNP, CPA3, CPD, CSF2, CSNK1D, CTSG, CTSZ, CYP3A4, CYP3A5, DAO, DBH, ACE, DDB2, GADD45A, DHX8, DHX9, DDX10, DDX11, DFFA, DFFB, DIO1, DIO3, SARDH, DNASE1L1, DNASE1L2, DNASE1L3, DNASE2, TRDMT1, DPAGT1, DPEP1, DYRK1A, ENPEP, SLC29A1, ERCC1, ERCC4, ERCC5, EXTL2, F7, F10, FANCA, FANCC, FANCD2, FANCE, FANCG, FEN1, AFF2, FUT8, GALC, GLUD1, GLUL, GM2A, GOT2, GPT, GRIN2A, GRSF1, GSTM1, GSTM2, GSTZ1, HSD17B10, HAL, HLCS, HPD, IDE, ISG20, IVD, KCNQ1, KPNA1, KPNB1, LTA4H, KITLG, MGMT, MKI67, ALDH6A1, CNOT4, NTHL1, OAS3, OAT, ORC5, PAH, PCCA, ENPP3, EXOSC9, PPP2R2A, PPP4C, PRKCG, PROC, PROS1, PSPH, PTBP1, PTPN1, RAD1, PYCR1, ALDH18A1, RAC1, RAD51, RAD51B, RAD51D, RAG1, RAG2, RBBP6, RBMS1, RNASE1, RNASE2, RNASE3, RNASE6, RNPEP, ABCE1, RP9, S100A11, SETMAR, TRA2B, SHC1, SHMT2, SLC5A5, SLC34A1, SLC22A5, SUMO3, SNRNP70, SNRPA, SNRPA1, SNRPC, SNRPD1, SNRPD2, SNRPN, SOD1, SON, SORL1, SRD5A1, SRPK2, SUOX, SUPV3L1, TAT, TOP1, TPMT, CCT3, TSN, TSHB, TST, UBE2V2, UNG, USP4, UVRAG, XPA, XPC, XPNPEP1, XRCC2, XRCC4, SHFM1, CDK2AP1, SF3A2, SYMPK, RBM10, SMC1A, FKBP6, PARG, COPS3, CDC14B, PRPF18, RRP1, PRKRA, RNASET2, ALDH4A1, BECN1, TNFSF13, BANF1, GGH, PROZ, VNN2, VNN1, SGPL1, SLC5A6, HERC2, MBD4, DIRAS3, SMC3, PRPF3, AIFM1, CCNE2, EXO1, PCSK7, SCAF11, VAPB, TRIP12, EFTUD2, GRHPR, RECQL4, SNRNP40, GSTO1, PICK1, IL27RA, CHD1L, BRE, ENTPD4, WTAP, KIAA0391, DHX34, UTP14C, RNF40, GINS1, DDX46, SMG7, PAN2, DCLRE1A, EXOG, USP3, SLC23A2, PTBP3, GNE, PARP2, PARP3, COL4A3BP, RAD50, G3BP1, SUGP2, AASS, ATP6AP2, DDX39A, SF3B4, CWC27, SMNDC1, BCKDK, CCNO, ABCA7, NSA2, CD2BP2, EMG1, OLFM1, PPIH, CHERP, RNASEH2A, RPP30, RPP38, CCT7, TBL3, RAD51AP1, SPHAR, CCT8, CORIN, USP39, UTP14A, ALDH1L1, CPSF4, TXNL4A, COPS8, DBF4, SRSF8, SF3A3, TMED10, COPS6, SF3B2, SNRNP27, CPSF6, DUS4L, ADAMTS13, RPP14, KRR1, CLASRP, NUDT3, WDHD1, INMT, WBP4, XPOT, DDX19B, TREX1, DDX42, EXOSC8 |