| GOBPID | Pvalue | OddsRatio | ExpCount | Count | Size | Term | Genes |
1 | GO:0051482 | 0.00 | Inf | 1.89 | 8 | 8 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | AGTR1, S1PR1, LPAR1, EDNRA, F2R, GRM1, HTR2C, KISS1 |
2 | GO:0009629 | 0.00 | Inf | 1.18 | 5 | 5 | response to gravity | BGLAP, CBLB, PTAFR, SPARC, FOSL1 |
3 | GO:0042148 | 0.00 | Inf | 1.18 | 5 | 5 | strand invasion | RAD51, RAD51C, RAD51B, RAD51D, XRCC2 |
4 | GO:0051918 | 0.00 | Inf | 1.18 | 5 | 5 | negative regulation of fibrinolysis | APOH, F2, HRG, SERPINE1, USF1 |
5 | GO:2000074 | 0.00 | Inf | 1.18 | 5 | 5 | regulation of type B pancreatic cell development | ARNTL, BAD, RFX3, RHEB, CLOCK |
6 | GO:0001774 | 0.00 | 22.69 | 1.89 | 7 | 8 | microglial cell activation | CLU, CX3CR1, IL13, JUN, CX3CL1, SNCA, TRPV1 |
7 | GO:0003085 | 0.00 | 22.69 | 1.89 | 7 | 8 | negative regulation of systemic arterial blood pressure | AGTR2, BBS4, BMPR2, NTSR1, PRCP, SOD2, KCNK6 |
8 | GO:0030194 | 0.00 | 19.49 | 1.65 | 6 | 7 | positive regulation of blood coagulation | CD36, F2R, F3, F7, S100A9, SELP |
9 | GO:0014819 | 0.00 | 19.44 | 1.65 | 6 | 7 | regulation of skeletal muscle contraction | ATP2A1, CASQ1, CAV3, KCNJ2, SLC8A3, GSTO1 |
10 | GO:0034616 | 0.00 | 19.44 | 1.65 | 6 | 7 | response to laminar fluid shear stress | ABCA1, ASS1, ETS1, SMAD6, SMAD7, KLF4 |
11 | GO:0048563 | 0.00 | 19.44 | 1.65 | 6 | 7 | post-embryonic organ morphogenesis | BAX, FBN1, EFEMP1, HMGN1, KDR, BCL2L11 |
12 | GO:0050667 | 0.00 | 19.44 | 1.65 | 6 | 7 | homocysteine metabolic process | AHCY, BHMT, COMT, CPS1, CTH, DPEP1 |
13 | GO:0009303 | 0.00 | 16.23 | 1.42 | 5 | 6 | rRNA transcription | ANG, GTF3A, BRF1, SMARCA4, TAF1B |
14 | GO:0035590 | 0.00 | 16.22 | 1.42 | 5 | 6 | purinergic nucleotide receptor signaling pathway | P2RX1, P2RX3, P2RX4, P2RX5, P2RX7 |
15 | GO:0050901 | 0.00 | 16.22 | 1.42 | 5 | 6 | leukocyte tethering or rolling | ITGB1, SELE, SELP, SELPLG, MADCAM1 |
16 | GO:0006704 | 0.00 | 16.19 | 1.42 | 5 | 6 | glucocorticoid biosynthetic process | ATP1A1, CRH, CYP11B1, HSD11B1, REST |
17 | GO:0006782 | 0.00 | 16.19 | 1.42 | 5 | 6 | protoporphyrinogen IX biosynthetic process | ALAD, ALAS2, CPOX, HMBS, UROS |
18 | GO:0007158 | 0.00 | 16.19 | 1.42 | 5 | 6 | neuron cell-cell adhesion | ASTN1, TNR, NRXN3, NRXN1, NRXN2 |
19 | GO:0007263 | 0.00 | 16.19 | 1.42 | 5 | 6 | nitric oxide mediated signal transduction | AGTR2, CD36, FPR1, KCNC2, SPINK1 |
20 | GO:0018119 | 0.00 | 16.19 | 1.42 | 5 | 6 | peptidyl-cysteine S-nitrosylation | ADH5, ACE, GAPDH, S100A8, S100A9 |
21 | GO:0022010 | 0.00 | 16.19 | 1.42 | 5 | 6 | central nervous system myelination | CLU, FGFR3, KCNJ10, PTEN, CNTN2 |
22 | GO:0031284 | 0.00 | 16.19 | 1.42 | 5 | 6 | positive regulation of guanylate cyclase activity | GUCA1A, GUCA2A, GUCA2B, RCVRN, GUCA1C |
23 | GO:0035234 | 0.00 | 16.19 | 1.42 | 5 | 6 | ectopic germ cell programmed cell death | BAX, CASP5, IL1A, KIT, KITLG |
24 | GO:0035641 | 0.00 | 16.19 | 1.42 | 5 | 6 | locomotory exploration behavior | CRH, DPP4, PENK, PRKCE, TNR |
25 | GO:0042791 | 0.00 | 16.19 | 1.42 | 5 | 6 | 5S class rRNA transcription from RNA polymerase III type 1 promoter | GTF3C1, GTF3C2, GTF3C5, GTF3C4, GTF3C3 |
26 | GO:0042797 | 0.00 | 16.19 | 1.42 | 5 | 6 | tRNA transcription from RNA polymerase III promoter | GTF3C1, GTF3C2, GTF3C5, GTF3C4, GTF3C3 |
27 | GO:0044144 | 0.00 | 16.19 | 1.42 | 5 | 6 | modulation of growth of symbiont involved in interaction with host | CD36, IFNG, IL10, IL12B, OSBP |
28 | GO:0060158 | 0.00 | 16.19 | 1.42 | 5 | 6 | phospholipase C-activating dopamine receptor signaling pathway | DRD5, GNA15, GNAQ, SLC9A3R1, GNA14 |
29 | GO:0070886 | 0.00 | 16.19 | 1.42 | 5 | 6 | positive regulation of calcineurin-NFAT signaling cascade | NRG1, IGF1, SLC9A1, SLC12A1, AKAP6 |
30 | GO:0033574 | 0.00 | 15.17 | 4.02 | 14 | 17 | response to testosterone | BAD, BGLAP, BMP4, TSPO, CDK4, DNMT1, DUSP1, ELK1, HMGCS2, KCNJ11, PLN, PSPH, RPS6KB1, SRD5A1 |
31 | GO:1903426 | 0.00 | 13.04 | 2.35 | 8 | 10 | regulation of reactive oxygen species biosynthetic process | TSPO, IGF1, IL10, PTGIS, SNCA, STAT3, RGN, TRAP1 |
32 | GO:0038084 | 0.00 | 12.99 | 2.36 | 8 | 10 | vascular endothelial growth factor signaling pathway | FLT1, FLT3, FLT4, HSPB1, KDR, PRKD1, NRP2, NRP1 |
33 | GO:0010248 | 0.00 | 12.97 | 2.36 | 8 | 10 | establishment or maintenance of transmembrane electrochemical gradient | ATP1A1, ATP1A2, ATP1A3, ATP12A, FXYD2, ATP4A, BAX, SLC22A1 |
34 | GO:0016558 | 0.00 | 12.97 | 2.36 | 8 | 10 | protein import into peroxisome matrix | PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX5, PEX16 |
35 | GO:0071941 | 0.00 | 12.97 | 2.36 | 8 | 10 | nitrogen cycle metabolic process | ARG1, ARG2, ASL, ASS1, CPS1, SUOX, NR1H4, SLC25A15 |
36 | GO:0010524 | 0.00 | 11.40 | 2.12 | 7 | 9 | positive regulation of calcium ion transport into cytosol | BMP4, CD4, P2RX3, P2RX4, P2RX5, P2RX7, TRPC3 |
37 | GO:0033762 | 0.00 | 11.40 | 2.12 | 7 | 9 | response to glucagon | CDO1, CREB1, CYC1, HMGCS2, QDPR, RPS6KB1, SREBF1 |
38 | GO:0030207 | 0.00 | 11.34 | 2.13 | 7 | 9 | chondroitin sulfate catabolic process | VCAN, CSPG4, DCN, HEXA, HEXB, IDS, IDUA |
39 | GO:0042511 | 0.00 | 11.34 | 2.13 | 7 | 9 | positive regulation of tyrosine phosphorylation of Stat1 protein | FGFR3, HPX, IFNG, KIT, TNFRSF1A, TNFRSF18, TNFSF18 |
40 | GO:0007214 | 0.00 | 10.82 | 3.07 | 10 | 13 | gamma-aminobutyric acid signaling pathway | ATF4, CACNA1A, CACNB4, GABRA4, GABRA5, GABRE, GABRG1, GABRR1, GABRR2, GABBR2 |
41 | GO:0032735 | 0.00 | 10.82 | 3.07 | 10 | 13 | positive regulation of interleukin-12 production | CD36, IFNG, IL12B, IDO1, IRF1, IRF5, ISL1, TNFSF4, TNFSF9, RIPK2 |
42 | GO:0043574 | 0.00 | 10.82 | 3.07 | 10 | 13 | peroxisomal transport | ABCD1, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX19, PEX5, PEX16 |
43 | GO:0071887 | 0.00 | 9.78 | 1.88 | 6 | 8 | leukocyte apoptotic process | CLC, DFFA, IFNG, IL2RA, RIPK1, BCL2L11 |
44 | GO:0042417 | 0.00 | 9.74 | 1.89 | 6 | 8 | dopamine metabolic process | AGTR2, DBH, DRD3, GRIN2A, SNCB, SNCAIP |
45 | GO:0033189 | 0.00 | 9.73 | 2.84 | 9 | 12 | response to vitamin A | ARG1, CAT, DNMT1, DNMT3B, GATA4, RARA, RXRA, SLC34A1, TYMS |
46 | GO:0072663 | 0.00 | 9.73 | 2.84 | 9 | 12 | establishment of protein localization to peroxisome | PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX19, PEX5, PEX16 |
47 | GO:0000050 | 0.00 | 9.72 | 1.89 | 6 | 8 | urea cycle | ARG1, ARG2, ASL, ASS1, CPS1, SLC25A15 |
48 | GO:0002517 | 0.00 | 9.72 | 1.89 | 6 | 8 | T cell tolerance induction | CBLB, CD3E, CD86, CLC, IL2RA, IDO1 |
49 | GO:0002643 | 0.00 | 9.72 | 1.89 | 6 | 8 | regulation of tolerance induction | CBLB, CD3E, CD86, CLC, IL2RA, IDO1 |
50 | GO:0030007 | 0.00 | 9.72 | 1.89 | 6 | 8 | cellular potassium ion homeostasis | ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP4A, KCNJ2 |
51 | GO:0030238 | 0.00 | 9.72 | 1.89 | 6 | 8 | male sex determination | NR0B1, IGF1R, INSRR, PTGDR, SOX9, SRY |
52 | GO:0036376 | 0.00 | 9.72 | 1.89 | 6 | 8 | sodium ion export from cell | ATP1A1, ATP1A2, ATP1A3, ATP12A, FXYD2, ATP4A |
53 | GO:0043312 | 0.00 | 9.72 | 1.89 | 6 | 8 | neutrophil degranulation | ANXA3, BCR, PTAFR, STXBP2, STXBP3, STX11 |
54 | GO:0048935 | 0.00 | 9.72 | 1.89 | 6 | 8 | peripheral nervous system neuron development | HOXD9, HOXD10, ISL1, NTRK2, TBCE, ONECUT2 |
55 | GO:0051775 | 0.00 | 9.72 | 1.89 | 6 | 8 | response to redox state | ADH5, ARHGDIB, ARNTL, RYR2, CLOCK, RNF7 |
56 | GO:0055012 | 0.00 | 9.72 | 1.89 | 6 | 8 | ventricular cardiac muscle cell differentiation | CCNB1, NRG1, RARA, RARB, RXRA, ATG5 |
57 | GO:0060433 | 0.00 | 9.72 | 1.89 | 6 | 8 | bronchus development | BMP4, IL13, SOX9, SRF, TULP3, ADAMTSL2 |
58 | GO:2000811 | 0.00 | 9.72 | 1.89 | 6 | 8 | negative regulation of anoikis | BCL2L1, ITGA5, ITGB1, NTRK2, PDK4, PTK2 |
59 | GO:0043278 | 0.00 | 8.93 | 3.54 | 11 | 15 | response to morphine | ADRA1B, CNR1, DRD3, EDNRA, FGA, PENK, PPP2R2A, PPP5C, PRKCE, TACR3, PEA15 |
60 | GO:0060055 | 0.00 | 8.65 | 2.60 | 8 | 11 | angiogenesis involved in wound healing | ETS1, B4GALT1, GPX1, SERPINE1, PRCP, CX3CL1, SRF, VEGFB |
61 | GO:0097296 | 0.00 | 8.65 | 2.60 | 8 | 11 | activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | BAX, SMAD3, TRAF2, TRADD, RIPK1, TNFSF10, TNFRSF10B, TNFRSF10A |
62 | GO:0001974 | 0.00 | 8.46 | 4.25 | 13 | 18 | blood vessel remodeling | ACVR2B, ACVRL1, ADRA1B, AGTR2, AXL, BAX, BMPR2, DBH, ACE, IGF1, RBPJ, ITGA4, ATG5 |
63 | GO:0042220 | 0.00 | 8.46 | 4.25 | 13 | 18 | response to cocaine | BAX, CHRNB2, CNR1, CRH, CRHBP, DNM2, DNMT3B, DRD5, PTK2B, HNMT, OXTR, TACR3, EFTUD2 |
64 | GO:0034767 | 0.00 | 8.18 | 6.60 | 20 | 28 | positive regulation of ion transmembrane transport | ABL1, ARF1, BAX, CRH, DPP6, EDNRA, F2, F2R, GCG, IL13, KCNC2, KCNH2, KCNJ2, KCNQ1, P2RX7, XCL1, SLC34A1, SNCA, STC1, TRPC1 |
65 | GO:0022602 | 0.01 | 8.17 | 1.64 | 5 | 7 | ovulation cycle process | KISS1, PAM, PGR, NRIP1, SLIT2 |
66 | GO:0014068 | 0.00 | 8.16 | 8.27 | 25 | 35 | positive regulation of phosphatidylinositol 3-kinase signaling | ANGPT1, CAT, CBL, CD28, DCN, F2, F2R, FGR, FLT1, FLT3, FSHR, FYN, HCLS1, HGF, NRG1, IGF1, INS, KDR, KIT, NTRK2, PTK2, PTPN6, SELP, SOX9, UBE3A |
67 | GO:0001553 | 0.01 | 8.09 | 1.65 | 5 | 7 | luteinization | CAPN5, GDF9, PTPRN, STAT5B, FZD4 |
68 | GO:0002016 | 0.01 | 8.09 | 1.65 | 5 | 7 | regulation of blood volume by renin-angiotensin | AGTR1, AGTR2, CYBA, ACE, DRD3 |
69 | GO:0006105 | 0.01 | 8.09 | 1.65 | 5 | 7 | succinate metabolic process | GAD1, SDHA, SDHB, STAT5B, SUCLG1 |
70 | GO:0010640 | 0.01 | 8.09 | 1.65 | 5 | 7 | regulation of platelet-derived growth factor receptor signaling pathway | F3, F7, PTPRJ, SNCA, SLC9A3R1 |
71 | GO:0014854 | 0.01 | 8.09 | 1.65 | 5 | 7 | response to inactivity | CASQ1, CAT, F2, IL10, SCN5A |
72 | GO:0015810 | 0.01 | 8.09 | 1.65 | 5 | 7 | aspartate transport | ABAT, NTSR1, SLC1A6, SLC25A12, SLC25A13 |
73 | GO:0019740 | 0.01 | 8.09 | 1.65 | 5 | 7 | nitrogen utilization | BAX, RHAG, RHCE, RHD, NR1H4 |
74 | GO:0051597 | 0.01 | 8.09 | 1.65 | 5 | 7 | response to methylmercury | ALAD, ARG1, CCNE1, CPOX, HMBS |
75 | GO:0060045 | 0.01 | 8.09 | 1.65 | 5 | 7 | positive regulation of cardiac muscle cell proliferation | CCNB1, GATA4, GATA6, NRG1, RBPJ |
76 | GO:0060080 | 0.01 | 8.09 | 1.65 | 5 | 7 | inhibitory postsynaptic potential | ABAT, GLRA1, NTSR1, CX3CL1, RIMS2 |
77 | GO:0060134 | 0.01 | 8.09 | 1.65 | 5 | 7 | prepulse inhibition | DRD3, FABP7, GRID2, PTEN, NRXN1 |
78 | GO:0060253 | 0.01 | 8.09 | 1.65 | 5 | 7 | negative regulation of glial cell proliferation | ASCL2, TSPO, PTN, SOX11, RNF10 |
79 | GO:0060379 | 0.01 | 8.09 | 1.65 | 5 | 7 | cardiac muscle cell myoblast differentiation | NRG1, RBPJ, ISL1, REST, SRF |
80 | GO:0060442 | 0.01 | 8.09 | 1.65 | 5 | 7 | branching involved in prostate gland morphogenesis | BMP4, CD44, IGF1, RXRA, FEM1B |
81 | GO:0061117 | 0.01 | 8.09 | 1.65 | 5 | 7 | negative regulation of heart growth | CAV3, CXADR, KCNK2, TP73, CTDP1 |
82 | GO:0061549 | 0.01 | 8.09 | 1.65 | 5 | 7 | sympathetic ganglion development | ASCL1, SEMA3F, NRP2, NRP1, PHOX2B |
83 | GO:0071550 | 0.01 | 8.09 | 1.65 | 5 | 7 | death-inducing signaling complex assembly | RAF1, TNFRSF1A, TRAF2, TRADD, RIPK1 |
84 | GO:0090344 | 0.01 | 8.09 | 1.65 | 5 | 7 | negative regulation of cell aging | ABL1, CDK6, PTEN, WNT1, TP63 |
85 | GO:1900119 | 0.01 | 8.09 | 1.65 | 5 | 7 | positive regulation of execution phase of apoptosis | BAX, BOK, FAP, PTGIS, RPS3 |
86 | GO:0006297 | 0.00 | 7.56 | 2.36 | 7 | 10 | nucleotide-excision repair, DNA gap filling | PCNA, RFC3, RFC4, RFC5, RPA2, RPA3, UBB |
87 | GO:0060421 | 0.00 | 7.56 | 2.36 | 7 | 10 | positive regulation of heart growth | ACACB, CCNB1, GATA4, GATA6, NRG1, RBPJ, AKAP6 |
88 | GO:0071257 | 0.00 | 7.56 | 2.36 | 7 | 10 | cellular response to electrical stimulus | ADSS, GNAT1, GRM1, IGF1, PALM, REST, SLC9A1 |
89 | GO:0002068 | 0.00 | 7.30 | 3.07 | 9 | 13 | glandular epithelial cell development | ARNTL, BAD, BMP4, CDK6, RARA, RARB, RFX3, RHEB, CLOCK |
90 | GO:0032201 | 0.00 | 7.30 | 3.07 | 9 | 13 | telomere maintenance via semi-conservative replication | FEN1, PCNA, PRIM2, UPF1, RFC3, RFC4, RFC5, RPA2, RPA3 |
91 | GO:0001508 | 0.00 | 7.10 | 4.46 | 13 | 19 | action potential | ATP1A1, CACNB4, CHRNB4, GLRA1, GNAQ, KCNC2, KCNQ1, NRCAM, CNTNAP1, AKAP7, AKAP6, NUP155, HCN4 |
92 | GO:0043434 | 0.00 | 6.78 | 5.49 | 16 | 24 | response to peptide hormone | ANXA1, STS, BSG, COL1A1, CTGF, EIF2B1, GNAI1, JUND, LIPC, LTA4H, OXTR, SPARC, TRPV1, EIF2B3, EIF2B2, RNF40 |
93 | GO:1903036 | 0.00 | 6.55 | 4.93 | 14 | 21 | positive regulation of response to wounding | ANXA1, APOH, CD36, F2, F2R, F3, F7, HRG, NTRK3, PRKCE, SELP, USF1, VEGFB, VTN |
94 | GO:0070542 | 0.00 | 6.54 | 2.82 | 8 | 12 | response to fatty acid | ALAD, BAD, CAT, CD36, CTGF, FFAR1, LIPC, PTGS1 |
95 | GO:0050921 | 0.01 | 6.53 | 2.11 | 6 | 9 | positive regulation of chemotaxis | BMPR2, LPAR1, HSPB1, PRKD1, NRP1, SLIT2 |
96 | GO:1900407 | 0.00 | 6.51 | 4.96 | 14 | 21 | regulation of cellular response to oxidative stress | ATF4, CD36, DHFR, FUT8, GPX1, HGF, HP, HSPB1, INS, PSAP, PYCR1, SOD2, BAG5, TRAP1 |
97 | GO:0050918 | 0.00 | 6.50 | 2.83 | 8 | 12 | positive chemotaxis | ANGPT1, ANGPT2, BMP4, FGF7, HGF, PTPRJ, SAA4, NRP1 |
98 | GO:0006335 | 0.00 | 6.50 | 4.96 | 14 | 21 | DNA replication-dependent nucleosome assembly | CHAF1B, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HAT1, HIST1H3F |
99 | GO:0010288 | 0.00 | 6.50 | 2.83 | 8 | 12 | response to lead ion | APP, CAT, CDK4, CPOX, PPP5C, QDPR, SLC34A1, SPARC |
100 | GO:0060416 | 0.01 | 6.49 | 2.12 | 6 | 9 | response to growth hormone | ASS1, CPS1, F7, HMGCS2, SLC34A1, SRD5A1 |
101 | GO:0071312 | 0.00 | 6.49 | 4.25 | 12 | 18 | cellular response to alkaloid | BAD, BCL2L1, CASQ2, CRH, CRHBP, ICAM1, KCNJ11, RAD51, RYR1, RYR2, SLC34A1, TRPV1 |
102 | GO:1902883 | 0.01 | 6.49 | 2.12 | 6 | 9 | negative regulation of response to oxidative stress | ATF4, GPX1, HSPB1, INS, SOD2, BAG5 |
103 | GO:0071242 | 0.00 | 6.49 | 3.54 | 10 | 15 | cellular response to ammonium ion | ABL1, ASS1, CRH, CRHBP, DIAPH1, DNM2, HRH1, KCNC2, PTAFR, SLC34A1 |
104 | GO:0010592 | 0.00 | 6.48 | 2.84 | 8 | 12 | positive regulation of lamellipodium assembly | DNM2, RAC1, RAC2, FSCN1, CLRN1, WNT1, ARPC2, WASF2 |
105 | GO:0042276 | 0.00 | 6.48 | 2.84 | 8 | 12 | error-prone translesion synthesis | PCNA, REV3L, RFC3, RFC4, RFC5, RPA2, RPA3, UBB |
106 | GO:0051491 | 0.00 | 6.48 | 2.84 | 8 | 12 | positive regulation of filopodium assembly | DPYSL3, GPM6A, PALM, PRKCQ, RALA, CCL21, FSCN1, SRF |
107 | GO:0060765 | 0.00 | 6.48 | 2.84 | 8 | 12 | regulation of androgen receptor signaling pathway | DDX5, EP300, IGF1, RNF6, SMARCA4, BUD31, RNF14, HDAC6 |
108 | GO:0002070 | 0.01 | 6.48 | 2.13 | 6 | 9 | epithelial cell maturation | CDKN1A, PGR, RFX3, SIX3, TYMS, FEM1B |
109 | GO:0003298 | 0.01 | 6.48 | 2.13 | 6 | 9 | physiological muscle hypertrophy | AGTR2, CAV3, GATA4, SORBS2, CTDP1, AKAP6 |
110 | GO:0030220 | 0.01 | 6.48 | 2.13 | 6 | 9 | platelet formation | ACTN1, CASP9, EP300, PTPN6, SRF, TAL1 |
111 | GO:0030825 | 0.01 | 6.48 | 2.13 | 6 | 9 | positive regulation of cGMP metabolic process | FZD2, GUCA1A, GUCA2A, GUCA2B, RCVRN, GUCA1C |
112 | GO:0035994 | 0.01 | 6.48 | 2.13 | 6 | 9 | response to muscle stretch | CAV3, CHUK, JUN, RAF1, RYR2, SLC9A1 |
113 | GO:0042053 | 0.01 | 6.48 | 2.13 | 6 | 9 | regulation of dopamine metabolic process | ABAT, CHRNB2, COMT, HPRT1, SNCA, TACR3 |
114 | GO:0048532 | 0.01 | 6.48 | 2.13 | 6 | 9 | anatomical structure arrangement | BMPR1A, EGR2, RAC1, SEMA3F, USP9X, NRP1 |
115 | GO:0060218 | 0.01 | 6.48 | 2.13 | 6 | 9 | hematopoietic stem cell differentiation | CDK6, CHD2, ACE, SRF, TAL1, XRCC5 |
116 | GO:0061049 | 0.01 | 6.48 | 2.13 | 6 | 9 | cell growth involved in cardiac muscle cell development | AGTR2, CAV3, GATA4, SORBS2, CTDP1, AKAP6 |
117 | GO:0010107 | 0.00 | 6.10 | 5.43 | 15 | 23 | potassium ion import | ATP1A3, ATP12A, ATP4A, KCNJ1, KCNJ2, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ14, KCNJ16, SLC12A6, ABCC9 |
118 | GO:0019228 | 0.00 | 6.03 | 4.73 | 13 | 20 | neuronal action potential | DPP6, IFNG, KCNA1, KCND2, P2RX1, P2RX3, P2RX4, SCN1A, SCN2A, SCN5A, SCN7A, SCN8A, KCNMB2 |
119 | GO:0051281 | 0.00 | 6.03 | 4.73 | 13 | 20 | positive regulation of release of sequestered calcium ion into cytosol | ABL1, BAX, CALM3, EDNRA, F2, F2R, IL13, NTSR1, XCL1, SNCA, TRPC1, GSTO1, AKAP6 |
120 | GO:0055021 | 0.00 | 5.95 | 4.02 | 11 | 17 | regulation of cardiac muscle tissue growth | CAV3, CCNB1, CXADR, GATA4, GATA6, NRG1, RBPJ, KCNK2, TP73, CTDP1, AKAP6 |
121 | GO:0072488 | 0.00 | 5.95 | 4.02 | 11 | 17 | ammonium transmembrane transport | ACACB, CPT1B, CPT2, RHAG, RHCE, RHD, SLC12A2, SLC22A1, SLC22A3, SLC22A2, SLC22A5 |
122 | GO:1901522 | 0.00 | 5.95 | 4.02 | 11 | 17 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus | ATF4, RUNX2, DLX5, EP300, FOXA2, RBPJ, SMAD1, SMAD9, RXRA, RXRG, USF1 |
123 | GO:0045669 | 0.00 | 5.86 | 6.62 | 18 | 28 | positive regulation of osteoblast differentiation | ACVR2B, ATP6AP1, BMP4, BMPR1A, BMPR2, RUNX2, DLX5, GNAS, HGF, IGF1, ILK, JUND, LTF, SMAD1, PRKD1, SOX11, TP63, PDLIM7 |
124 | GO:0000722 | 0.00 | 5.84 | 3.31 | 9 | 14 | telomere maintenance via recombination | FEN1, PCNA, PRIM2, RAD51, RFC3, RFC4, RFC5, RPA2, RPA3 |
125 | GO:0006883 | 0.00 | 5.84 | 3.31 | 9 | 14 | cellular sodium ion homeostasis | AGTR2, ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP4A, SGK1, SLC9A1, SGK2 |
126 | GO:0035282 | 0.01 | 5.69 | 2.59 | 7 | 11 | segmentation | BMI1, BMP4, EGR2, HOXD8, SEMA3F, FZD5, NRP1 |
127 | GO:1901216 | 0.01 | 5.69 | 2.59 | 7 | 11 | positive regulation of neuron death | ABL1, BAD, CLU, ELK1, TRPM2, AIMP2, PICALM |
128 | GO:0001954 | 0.01 | 5.69 | 2.59 | 7 | 11 | positive regulation of cell-matrix adhesion | CD36, CDK6, EMP2, PTK2B, ILK, CCL21, CCL25 |
129 | GO:0002548 | 0.00 | 5.69 | 5.20 | 14 | 22 | monocyte chemotaxis | ANXA1, FLT1, SERPINE1, RPS19, S100A7, S100A12, CCL21, CCL22, CCL25, XCL1, CX3CL1, XCL2, TNFSF18, SLIT2 |
130 | GO:0072350 | 0.00 | 5.69 | 5.20 | 14 | 22 | tricarboxylic acid metabolic process | ACO2, ASS1, GLUD1, IDH1, IDH3A, MDH2, OGDH, SDHA, SDHB, SDHC, SDHD, SLC34A1, STAT5B, SUCLG1 |
131 | GO:0060443 | 0.01 | 5.68 | 2.59 | 7 | 11 | mammary gland morphogenesis | ARG1, BAX, BMP4, CAPN1, B4GALT1, PAX3, STAT6 |
132 | GO:0010881 | 0.01 | 5.67 | 2.60 | 7 | 11 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion | ATP1A2, CALM3, CASQ2, HRC, PLN, RYR2, GSTO1 |
133 | GO:0033141 | 0.01 | 5.67 | 2.60 | 7 | 11 | positive regulation of peptidyl-serine phosphorylation of STAT protein | IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1 |
134 | GO:0045086 | 0.01 | 5.67 | 2.60 | 7 | 11 | positive regulation of interleukin-2 biosynthetic process | CD3E, CD4, CD28, CD86, IL1A, PRKCQ, STAT5B |
135 | GO:0034694 | 0.00 | 5.56 | 4.49 | 12 | 19 | response to prostaglandin | GNAS, HMGCS2, P2RY4, P2RY6, PRKAA1, PRKCE, PTGDR, PTGER2, CCL21, TNFSF4, YY1, AKR1C3 |
136 | GO:0030804 | 0.02 | 5.42 | 1.88 | 5 | 8 | positive regulation of cyclic nucleotide biosynthetic process | GUCA1A, GUCA2A, GUCA2B, RCVRN, GUCA1C |
137 | GO:0033627 | 0.02 | 5.42 | 1.88 | 5 | 8 | cell adhesion mediated by integrin | ICAM1, ITGA5, ITGB1, ADAM17, VTN |
138 | GO:0006312 | 0.02 | 5.41 | 1.89 | 5 | 8 | mitotic recombination | RAD51C, RAD51B, RAD51D, XRCC2, RAD50 |
139 | GO:0002828 | 0.00 | 5.41 | 3.78 | 10 | 16 | regulation of type 2 immune response | ANXA1, CD86, ECM1, IFNA2, IDO1, RARA, XCL1, STAT6, TNFSF4, IL27RA |
140 | GO:0006099 | 0.00 | 5.41 | 3.78 | 10 | 16 | tricarboxylic acid cycle | ACO2, IDH1, IDH3A, MDH2, OGDH, SDHA, SDHB, SDHC, SDHD, SUCLG1 |
141 | GO:0043552 | 0.00 | 5.41 | 3.78 | 10 | 16 | positive regulation of phosphatidylinositol 3-kinase activity | EPHA8, PTK2B, FGFR3, FGR, FLT1, FLT3, KIT, PTK2, RAC1, CCL21 |
142 | GO:0086004 | 0.00 | 5.41 | 3.78 | 10 | 16 | regulation of cardiac muscle cell contraction | ATP1A1, ATP1A2, GATA4, KCNJ2, PDE4B, PLN, RYR2, SCN5A, STC1, SUMO1 |
143 | GO:0003417 | 0.02 | 5.40 | 1.89 | 5 | 8 | growth plate cartilage development | COL9A1, COMP, RARA, RARB, STC1 |
144 | GO:0005513 | 0.02 | 5.40 | 1.89 | 5 | 8 | detection of calcium ion | CALM3, CASQ2, RYR2, SYT1, KCNMB2 |
145 | GO:0010669 | 0.02 | 5.40 | 1.89 | 5 | 8 | epithelial structure maintenance | CXADR, SLC22A5, SOX9, SRF, CROCC |
146 | GO:0010820 | 0.02 | 5.40 | 1.89 | 5 | 8 | positive regulation of T cell chemotaxis | ADAM10, S100A7, XCL1, ADAM17, TNFSF14 |
147 | GO:0014002 | 0.02 | 5.40 | 1.89 | 5 | 8 | astrocyte development | CDK6, GFAP, S100A8, S100A9, VIM |
148 | GO:0019371 | 0.02 | 5.40 | 1.89 | 5 | 8 | cyclooxygenase pathway | CBR1, HPGD, PTGIS, PTGS1, AKR1C3 |
149 | GO:0019852 | 0.02 | 5.40 | 1.89 | 5 | 8 | L-ascorbic acid metabolic process | CYB5A, CYB5R3, SLC2A3, RGN, GSTO1 |
150 | GO:0021794 | 0.02 | 5.40 | 1.89 | 5 | 8 | thalamus development | CHRNB2, OGDH, PTN, SRD5A1, OLIG2 |
151 | GO:0021978 | 0.02 | 5.40 | 1.89 | 5 | 8 | telencephalon regionalization | BMP4, EMX1, EMX2, SIX3, NR2F1 |
152 | GO:0035864 | 0.02 | 5.40 | 1.89 | 5 | 8 | response to potassium ion | CLU, CRHBP, CYP11B1, KCNJ1, SLC34A1 |
153 | GO:0036037 | 0.02 | 5.40 | 1.89 | 5 | 8 | CD8-positive, alpha-beta T cell activation | TNFSF8, IFNG, IRF1, SATB1, XCL1 |
154 | GO:0042448 | 0.02 | 5.40 | 1.89 | 5 | 8 | progesterone metabolic process | FSHB, SRD5A1, STAT5B, AKR1C3, DHRS9 |
155 | GO:0042832 | 0.02 | 5.40 | 1.89 | 5 | 8 | defense response to protozoan | BCL3, CD37, IFNG, IL10, IL12B |
156 | GO:0043173 | 0.02 | 5.40 | 1.89 | 5 | 8 | nucleotide salvage | AMPD1, AMPD2, APRT, HPRT1, UPP1 |
157 | GO:0043174 | 0.02 | 5.40 | 1.89 | 5 | 8 | nucleoside salvage | APRT, CDA, TYMP, HPRT1, UPP1 |
158 | GO:0045821 | 0.02 | 5.40 | 1.89 | 5 | 8 | positive regulation of glycolytic process | ARNT, IGF1, INS, P2RX7, PRKAA1 |
159 | GO:0046040 | 0.02 | 5.40 | 1.89 | 5 | 8 | IMP metabolic process | ADSS, AMPD1, AMPD2, HPRT1, PFAS |
160 | GO:0046541 | 0.02 | 5.40 | 1.89 | 5 | 8 | saliva secretion | AQP5, CHRM1, CHRM3, KCNN4, TRPC1 |
161 | GO:0046689 | 0.02 | 5.40 | 1.89 | 5 | 8 | response to mercury ion | ALAD, ALB, BSG, SLC34A1, TAT |
162 | GO:0051194 | 0.02 | 5.40 | 1.89 | 5 | 8 | positive regulation of cofactor metabolic process | ARNT, IGF1, INS, P2RX7, PRKAA1 |
163 | GO:0051284 | 0.02 | 5.40 | 1.89 | 5 | 8 | positive regulation of sequestering of calcium ion | CALM3, CASQ2, NTSR1, RYR2, GSTO1 |
164 | GO:0055093 | 0.02 | 5.40 | 1.89 | 5 | 8 | response to hyperoxia | CAT, CDK4, CDKN1A, COL1A1, DNMT3B |
165 | GO:0060219 | 0.02 | 5.40 | 1.89 | 5 | 8 | camera-type eye photoreceptor cell differentiation | GNAT2, IHH, PTN, SOX9, SLC4A7 |
166 | GO:0060707 | 0.02 | 5.40 | 1.89 | 5 | 8 | trophoblast giant cell differentiation | PRDM1, SNAI1, NR2F2, SOCS3, HAND1 |
167 | GO:0060736 | 0.02 | 5.40 | 1.89 | 5 | 8 | prostate gland growth | IGF1, PSAP, PTEN, SOX9, UBE3A |
168 | GO:0061440 | 0.02 | 5.40 | 1.89 | 5 | 8 | kidney vasculature development | ANGPT1, ANGPT2, BMP4, SERPINB7, NRP1 |
169 | GO:0070365 | 0.02 | 5.40 | 1.89 | 5 | 8 | hepatocyte differentiation | ANXA1, BMP4, CPS1, HHEX, WNT1 |
170 | GO:0070493 | 0.02 | 5.40 | 1.89 | 5 | 8 | thrombin receptor signaling pathway | F2R, F2RL2, GP1BA, HPGD, SNCA |
171 | GO:0072520 | 0.02 | 5.40 | 1.89 | 5 | 8 | seminiferous tubule development | ATRX, GATA4, ING2, UBB, REC8 |
172 | GO:0090201 | 0.02 | 5.40 | 1.89 | 5 | 8 | negative regulation of release of cytochrome c from mitochondria | BCL2L1, GPX1, HGF, IGF1, OPA1 |
173 | GO:1901032 | 0.02 | 5.40 | 1.89 | 5 | 8 | negative regulation of response to reactive oxygen species | HGF, HP, PSAP, PYCR1, TRAP1 |
174 | GO:1901889 | 0.02 | 5.40 | 1.89 | 5 | 8 | negative regulation of cell junction assembly | ACVRL1, ARHGAP6, ACE, PTEN, ITGB1BP1 |
175 | GO:1903205 | 0.02 | 5.40 | 1.89 | 5 | 8 | regulation of hydrogen peroxide-induced cell death | HGF, PSAP, PYCR1, HDAC6, TRAP1 |
176 | GO:2001044 | 0.02 | 5.40 | 1.89 | 5 | 8 | regulation of integrin-mediated signaling pathway | CD63, CTNNA1, EMP2, PRKD1, ITGB1BP1 |
177 | GO:0010596 | 0.00 | 5.20 | 3.07 | 8 | 13 | negative regulation of endothelial cell migration | APOH, KRIT1, DCN, SERPINF1, SP100, STC1, NR2F2, SLIT2 |
178 | GO:0007611 | 0.00 | 5.19 | 4.20 | 11 | 18 | learning or memory | STS, CRHBP, DBI, EGR2, AFF2, GM2A, MAN2B1, PRKAR1B, VIP, KCNAB1, FZD9 |
179 | GO:0003309 | 0.00 | 5.19 | 3.07 | 8 | 13 | type B pancreatic cell differentiation | ARNTL, BAD, BMP4, CDK6, GATA6, RFX3, RHEB, CLOCK |
180 | GO:0007597 | 0.00 | 5.19 | 3.07 | 8 | 13 | blood coagulation, intrinsic pathway | APOH, F2, F10, GP1BA, GP9, KLKB1, KNG1, PRCP |
181 | GO:0019098 | 0.00 | 5.19 | 3.07 | 8 | 13 | reproductive behavior | APLP2, APP, DBH, DRD5, GNAQ, HEXB, OXTR, PTEN |
182 | GO:0021854 | 0.00 | 5.19 | 3.07 | 8 | 13 | hypothalamus development | NR0B1, BAX, CRH, ETS1, SOX3, SRD5A1, UBB, NRP1 |
183 | GO:0031290 | 0.00 | 5.19 | 3.07 | 8 | 13 | retinal ganglion cell axon guidance | EFNA5, EPHB1, EPHB3, ISL1, NRCAM, RPL24, NRP1, SLIT2 |
184 | GO:0055119 | 0.00 | 5.19 | 3.07 | 8 | 13 | relaxation of cardiac muscle | ATP1A1, ATP1A2, HRC, KCNJ2, P2RX4, PDE4B, PLN, PDE5A |
185 | GO:0070306 | 0.00 | 5.19 | 3.07 | 8 | 13 | lens fiber cell differentiation | CRYGB, EPHA2, FGFR3, SMAD3, NTRK3, SIX3, VIM, ZEB2 |
186 | GO:0097009 | 0.00 | 5.19 | 3.07 | 8 | 13 | energy homeostasis | ACACB, AMPD2, CD36, PRCP, PRKAA1, STAT3, UBB, NR1D2 |
187 | GO:0071398 | 0.00 | 5.15 | 7.33 | 19 | 31 | cellular response to fatty acid | ASS1, CCNB1, CPS1, CREB1, GNAS, FFAR3, HMGCS2, P2RY4, P2RY6, PDK4, PRKAA1, PRKCE, PTAFR, PTGDR, PTGER2, SREBF1, TNFSF4, AKR1C3, NR1H4 |
188 | GO:0051898 | 0.00 | 5.10 | 4.25 | 11 | 18 | negative regulation of protein kinase B signaling | CRYBA1, DRD3, EPHA2, RAPGEF1, IGF1R, PTEN, PTPRJ, SFRP5, KLF4, SLC9A3R1, PDCD6 |
189 | GO:0050879 | 0.00 | 5.03 | 6.62 | 17 | 28 | multicellular organismal movement | ASCL1, ATP2A1, CACNA1A, CASQ1, CAV3, CHUK, DRD3, GAA, ITPR1, KCNJ2, RPS6KB1, SLC8A3, TNNC2, TNNC1, TNNI2, TNNI3, GSTO1 |
190 | GO:0046209 | 0.00 | 5.01 | 7.80 | 20 | 33 | nitric oxide metabolic process | AGTR2, ARG2, ASS1, TSPO, CALM3, CLU, CPS1, DHFR, DNM2, PTK2B, ICAM1, IFNG, IGF1, IL10, INS, P2RX4, PTGIS, TRPV1, RGN, KLF4 |
191 | GO:0043542 | 0.01 | 4.92 | 2.34 | 6 | 10 | endothelial cell migration | DPP4, FAP, PRKX, PTEN, S100A2, SCG2 |
192 | GO:2000379 | 0.00 | 4.90 | 4.71 | 12 | 20 | positive regulation of reactive oxygen species metabolic process | AGTR1, TSPO, CD36, CDKN1A, CRP, F2, GRB2, SNCA, AKR1C3, RIPK1, RGN, RNF41 |
193 | GO:0071346 | 0.00 | 4.90 | 4.71 | 12 | 20 | cellular response to interferon-gamma | ASS1, CD58, DAPK3, EPRS, GAPDH, IL12B, CCL21, CCL22, CCL25, XCL1, CX3CL1, XCL2 |
194 | GO:0007602 | 0.01 | 4.89 | 2.35 | 6 | 10 | phototransduction | GNAT2, GNGT2, RGR, TRPC3, UNC119, NR2E3 |
195 | GO:1904427 | 0.01 | 4.88 | 2.35 | 6 | 10 | positive regulation of calcium ion transmembrane transport | BMP4, RYR2, S100A1, SLC9A1, SUMO1, RGN |
196 | GO:0007585 | 0.00 | 4.88 | 4.72 | 12 | 20 | respiratory gaseous exchange | PHOX2A, COX15, CSF2RB, EDNRA, ELN, FUT8, HNMT, NTSR1, SFTPB, SFTPD, TMPRSS11D, TRAF4 |
197 | GO:1902041 | 0.00 | 4.87 | 3.54 | 9 | 15 | regulation of extrinsic apoptotic signaling pathway via death domain receptors | MAL, SP100, TRAF2, TRADD, RIPK1, TNFSF10, TNFRSF10B, TNFRSF10A, FEM1B |
198 | GO:0001776 | 0.01 | 4.87 | 2.36 | 6 | 10 | leukocyte homeostasis | ANXA1, FLT3, IFNG, KITLG, PDE4B, ADAM17 |
199 | GO:0060487 | 0.00 | 4.87 | 3.54 | 9 | 15 | lung epithelial cell differentiation | ASCL1, GATA6, FOXA2, RBPJ, IL13, NUMA1, SOX9, AIMP2, NUMB |
200 | GO:0031641 | 0.01 | 4.86 | 2.36 | 6 | 10 | regulation of myelination | IFNG, PTEN, RARA, RARB, RXRA, EIF2AK3 |
201 | GO:0051412 | 0.00 | 4.86 | 3.54 | 9 | 15 | response to corticosterone | ATP2B1, BAX, CALM3, CCNE1, CDKN1A, CRH, NTRK3, PTGS1, FOSL1 |
202 | GO:0061036 | 0.00 | 4.86 | 3.54 | 9 | 15 | positive regulation of cartilage development | ACVRL1, BMP1, BMP4, BMPR2, RUNX2, IHH, SMAD1, SMAD3, SOX9 |
203 | GO:2000403 | 0.00 | 4.86 | 3.54 | 9 | 15 | positive regulation of lymphocyte migration | ADAM10, PTK2B, ITGA4, S100A7, CCL21, XCL1, ADAM17, TNFSF14, CXCL14 |
204 | GO:0017187 | 0.01 | 4.86 | 2.36 | 6 | 10 | peptidyl-glutamic acid carboxylation | BGLAP, F2, F7, F10, PROC, PROZ |
205 | GO:0030049 | 0.01 | 4.86 | 2.36 | 6 | 10 | muscle filament sliding | TNNC2, TNNC1, TNNI2, TNNI3, TPM2, VIM |
206 | GO:0030826 | 0.01 | 4.86 | 2.36 | 6 | 10 | regulation of cGMP biosynthetic process | PTK2B, GUCA1A, GUCA2A, GUCA2B, RCVRN, GUCA1C |
207 | GO:0032878 | 0.01 | 4.86 | 2.36 | 6 | 10 | regulation of establishment or maintenance of cell polarity | KRIT1, PTK2B, FLOT2, IGF1, LLGL2, RNF41 |
208 | GO:0033057 | 0.01 | 4.86 | 2.36 | 6 | 10 | multicellular organism reproductive behavior | DBH, DRD5, GNAQ, HEXB, OXTR, PTEN |
209 | GO:0034349 | 0.01 | 4.86 | 2.36 | 6 | 10 | glial cell apoptotic process | APAF1, BAX, CASP9, PRKCI, RB1, TRAF2 |
210 | GO:0035988 | 0.01 | 4.86 | 2.36 | 6 | 10 | chondrocyte proliferation | BMPR2, CTGF, FGFR3, IHH, LTF, STC1 |
211 | GO:0042438 | 0.01 | 4.86 | 2.36 | 6 | 10 | melanin biosynthetic process | ASIP, CTNS, TRPC1, TYR, RAPGEF2, ZEB2 |
212 | GO:0044849 | 0.01 | 4.86 | 2.36 | 6 | 10 | estrous cycle | ANXA1, CLU, ETS1, OXTR, PTN, TRPM2 |
213 | GO:0060670 | 0.01 | 4.86 | 2.36 | 6 | 10 | branching involved in labyrinthine layer morphogenesis | GRB2, IL10, LLGL2, ST14, FZD5, SOCS3 |
214 | GO:0061298 | 0.01 | 4.86 | 2.36 | 6 | 10 | retina vasculature development in camera-type eye | ACVR2B, ACVRL1, BMPR2, FZD4, NRP1, SLC4A7 |
215 | GO:0071872 | 0.01 | 4.86 | 2.36 | 6 | 10 | cellular response to epinephrine stimulus | KCNQ1, PDE4B, RYR2, SLC9A1, SNCA, SRD5A1 |
216 | GO:0033002 | 0.00 | 4.73 | 10.37 | 26 | 44 | muscle cell proliferation | ANG, BMP4, COMT, CYBA, S1PR1, EDNRA, FLT1, HMGCR, IFNG, IGF1, IGFBP3, IL12B, IL13, ILK, IRAK1, JUN, ORC1, PTAFR, RPS6KB1, CX3CL1, SHC1, STAT5B, VIP, VIPR2, XRCC5, KLF4 |
217 | GO:0022008 | 0.00 | 4.69 | 9.37 | 24 | 42 | neurogenesis | ANXA1, BOK, CD9, VCAN, CSPG4, EIF2B1, FABP7, HEXB, HMBS, IGF1, KCNJ10, LLGL2, OMP, PENK, PTPRJ, S100A8, S100A9, SLC8A3, SMARCE1, TACC1, VTN, ZNF217, EIF2B3, EIF2B2 |
218 | GO:0021983 | 0.00 | 4.69 | 5.20 | 13 | 22 | pituitary gland development | NR0B1, BMP4, BMPR1A, CDH1, CREB1, ETS1, GHRHR, RBPJ, ISL1, SALL1, SIX3, SOX3, SRD5A1 |
219 | GO:0035094 | 0.00 | 4.69 | 5.20 | 13 | 22 | response to nicotine | ABAT, ATP1A2, BAD, CHRNB2, CHRNB4, CNR1, CREB1, IGF1, IGF2, IL13, KCNJ11, PENK, SHC1 |
220 | GO:0007159 | 0.01 | 4.67 | 2.77 | 7 | 12 | leukocyte cell-cell adhesion | ITGA5, ITGB1, OLR1, SELE, SELP, SELPLG, MADCAM1 |
221 | GO:0071385 | 0.00 | 4.65 | 4.01 | 10 | 17 | cellular response to glucocorticoid stimulus | ANXA1, ATP2B1, KLF9, FLT3, HMGCS2, ISL1, REST, SGK1, STC1, UBE2L3 |
222 | GO:0001707 | 0.00 | 4.64 | 4.01 | 10 | 17 | mesoderm formation | BMPR2, EPHA2, EXT2, SMAD3, PRKAR1A, SNAI1, SRF, WNT11, CHRD, HAND1 |
223 | GO:0015872 | 0.00 | 4.63 | 4.02 | 10 | 17 | dopamine transport | ABAT, CHRNB2, CNR1, DRD3, PCP4, RAB3B, SLC22A1, SLC22A3, SLC22A2, SNCA |
224 | GO:0043267 | 0.00 | 4.63 | 4.02 | 10 | 17 | negative regulation of potassium ion transport | ATF4, CASQ2, CAV3, PTK2B, KCNH2, KCNQ1, SUMO1, VIP, KCNAB1, OXSR1 |
225 | GO:0045879 | 0.00 | 4.63 | 4.02 | 10 | 17 | negative regulation of smoothened signaling pathway | RUNX2, CD3E, FGFR3, GPC3, PRKACB, RB1, SALL1, TULP3, PTCH2, CHRD |
226 | GO:0046685 | 0.00 | 4.63 | 4.02 | 10 | 17 | response to arsenic-containing substance | ALAD, ATF4, CDKN1A, CPOX, HMBS, SERPINF1, PTEN, RBM4, UROS, GSTO1 |
227 | GO:0070848 | 0.01 | 4.61 | 3.15 | 8 | 14 | response to growth factor | ANXA3, ASCL1, EPHA2, IL1R1, KCNC2, P2RY2, SCGB1A1, HDAC6 |
228 | GO:0071260 | 0.00 | 4.57 | 11.34 | 28 | 48 | cellular response to mechanical stimulus | ATP1A1, ATP1A2, BAD, BMP4, CASP5, TNFRSF8, CHEK1, CNN2, COL1A1, CYBA, EDNRA, F2, IGF2, IL13, IL13RA2, IRF1, ITGB1, KCNJ2, RAC1, SLC9A1, SOX9, TNFRSF1A, CRADD, TNFSF14, TNFRSF10B, TNFRSF10A, BAG3, CASP8AP2 |
229 | GO:0030521 | 0.01 | 4.55 | 2.83 | 7 | 12 | androgen receptor signaling pathway | CCNE1, SCGB2A1, RAN, RB1, UBE3A, NRIP1, NR1I3 |
230 | GO:0060350 | 0.01 | 4.55 | 2.83 | 7 | 12 | endochondral bone morphogenesis | BMPR2, COL9A1, COMP, RARA, RARB, SOX9, STC1 |
231 | GO:0007492 | 0.01 | 4.55 | 2.83 | 7 | 12 | endoderm development | BMPR1A, HHEX, ONECUT1, HOXC11, SMAD3, OTX2, PAX9 |
232 | GO:0009712 | 0.00 | 4.55 | 5.67 | 14 | 24 | catechol-containing compound metabolic process | ABAT, AGTR2, CHRNB2, COMT, DBH, DRD3, GRIN2A, HPRT1, PAH, SNCB, SNCA, SULT1A3, TACR3, SNCAIP |
233 | GO:0033683 | 0.00 | 4.55 | 5.67 | 14 | 24 | nucleotide-excision repair, DNA incision | ERCC3, ERCC4, NTHL1, PCNA, RFC3, RFC4, RFC5, RPA2, RPA3, UBB, XPA, CUL4A, CHD1L, RBX1 |
234 | GO:0051290 | 0.00 | 4.55 | 5.67 | 14 | 24 | protein heterotetramerization | RRM1, RRM2, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HIST1H3F |
235 | GO:0014003 | 0.01 | 4.55 | 2.83 | 7 | 12 | oligodendrocyte development | ASCL1, CD9, LPAR1, EIF2B1, SOX11, EIF2B3, EIF2B2 |
236 | GO:0007250 | 0.01 | 4.54 | 2.84 | 7 | 12 | activation of NF-kappaB-inducing kinase activity | IRAK1, TRAF2, IKBKG, TNFRSF10B, TNFRSF10A, TRAF4, TNFSF15 |
237 | GO:0010743 | 0.01 | 4.54 | 2.84 | 7 | 12 | regulation of macrophage derived foam cell differentiation | ABCA1, AGTR1, ALOX15B, CD36, CRP, ITGAV, NR1H2 |
238 | GO:0032731 | 0.01 | 4.54 | 2.84 | 7 | 12 | positive regulation of interleukin-1 beta production | CASP5, HSPB1, IFI16, IFNG, ISL1, SMAD3, P2RX7 |
239 | GO:0035574 | 0.01 | 4.54 | 2.84 | 7 | 12 | histone H4-K20 demethylation | HIST1H4I, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L |
240 | GO:0048070 | 0.01 | 4.54 | 2.84 | 7 | 12 | regulation of developmental pigmentation | BAX, GNAQ, IHH, KIT, KITLG, ZEB2, BCL2L11 |
241 | GO:0060334 | 0.01 | 4.54 | 2.84 | 7 | 12 | regulation of interferon-gamma-mediated signaling pathway | HPX, IFNG, IFNGR1, PTPN6, SUMO1, NR1H2, SOCS3 |
242 | GO:0070987 | 0.01 | 4.54 | 2.84 | 7 | 12 | error-free translesion synthesis | PCNA, RFC3, RFC4, RFC5, RPA2, RPA3, UBB |
243 | GO:0071380 | 0.01 | 4.54 | 2.84 | 7 | 12 | cellular response to prostaglandin E stimulus | GNAS, P2RY4, P2RY6, PRKAA1, PRKCE, PTGER2, TNFSF4 |
244 | GO:0071636 | 0.01 | 4.54 | 2.84 | 7 | 12 | positive regulation of transforming growth factor beta production | CREB1, SMAD3, XCL1, CX3CL1, WNT11, SERPINB7, ATP6AP2 |
245 | GO:0071731 | 0.01 | 4.54 | 2.84 | 7 | 12 | response to nitric oxide | BMP4, CDK2, DNM2, DPEP1, IL1R1, KCNC2, TRAF2 |
246 | GO:1901623 | 0.01 | 4.54 | 2.84 | 7 | 12 | regulation of lymphocyte chemotaxis | ADAM10, PTK2B, S100A7, XCL1, ADAM17, TNFSF14, CXCL14 |
247 | GO:0045815 | 0.00 | 4.53 | 10.16 | 25 | 43 | positive regulation of gene expression, epigenetic | ACTB, CHEK1, EP300, ERCC6, KAT2A, HMGA1, PHF2, TBP, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, HIST1H3F, TAF1B, TAF1A, BAZ1B, DDX21 |
248 | GO:0005980 | 0.00 | 4.46 | 4.49 | 11 | 19 | glycogen catabolic process | ADRA1B, CALM3, CPS1, G6PC, GAA, INS, PHKA2, PHKB, PHKG1, PYGB, PYGM |
249 | GO:0032570 | 0.00 | 4.46 | 4.49 | 11 | 19 | response to progesterone | BAD, TSPO, C3, CCNE1, OXTR, PTGER2, PTN, SREBF1, TYMS, FOSL1, SOCS3 |
250 | GO:0048661 | 0.00 | 4.43 | 6.14 | 15 | 26 | positive regulation of smooth muscle cell proliferation | BMP4, CYBA, S1PR1, FLT1, HMGCR, IGF1, IL13, IRAK1, JUN, ORC1, PTAFR, RPS6KB1, CX3CL1, SHC1, STAT5B |
251 | GO:0001938 | 0.00 | 4.41 | 9.45 | 23 | 40 | positive regulation of endothelial cell proliferation | ACVRL1, ANG, ARG1, ARNT, BMP4, BMPR2, CCR3, CYBA, ECM1, EGR3, F3, FGFR3, FLT4, NR4A1, JUN, KDR, PRKD1, VEGFB, VIP, SCG2, NRP2, NRP1, PDCD6 |
252 | GO:0043279 | 0.01 | 4.38 | 3.27 | 8 | 14 | response to alkaloid | BCHE, EDNRA, FGA, PPP2R2A, PPP5C, PRKCE, UQCRC1, PEA15 |
253 | GO:1900542 | 0.01 | 4.36 | 3.29 | 8 | 14 | regulation of purine nucleotide metabolic process | PTK2B, FZD2, GUCA1A, GUCA2A, GUCA2B, RCVRN, PDE5A, GUCA1C |
254 | GO:0030799 | 0.01 | 4.34 | 3.29 | 8 | 14 | regulation of cyclic nucleotide metabolic process | PTK2B, FZD2, GUCA1A, GUCA2A, GUCA2B, RCVRN, PDE5A, GUCA1C |
255 | GO:0030850 | 0.01 | 4.33 | 3.30 | 8 | 14 | prostate gland development | ALOX15B, ANXA1, BMP4, CD44, IGF1R, SERPINF1, SERPINB5, RARA |
256 | GO:0009880 | 0.01 | 4.33 | 3.30 | 8 | 14 | embryonic pattern specification | EFNB1, IHH, SMAD1, SMAD3, MEOX2, SEMA3F, SIM2, NRP1 |
257 | GO:0010812 | 0.01 | 4.33 | 3.30 | 8 | 14 | negative regulation of cell-substrate adhesion | ANGPT2, COL1A1, FBLN1, SPOCK1, TBCD, WNT1, FZD4, FZD7 |
258 | GO:0045844 | 0.00 | 4.33 | 4.96 | 12 | 21 | positive regulation of striated muscle tissue development | ARNTL, BMP4, CCNB1, GATA4, GATA6, NRG1, HMGCR, RBPJ, PRKAA1, RPS6KB1, USP2, AKAP6 |
259 | GO:0045907 | 0.00 | 4.33 | 4.96 | 12 | 21 | positive regulation of vasoconstriction | ADRA1B, AVPR1B, AVPR2, DBH, F2R, FGA, HRH1, ICAM1, OXTR, PTAFR, PTGS1, SHC1 |
260 | GO:0001958 | 0.01 | 4.32 | 3.31 | 8 | 14 | endochondral ossification | BMP4, RUNX2, COL1A1, DLX5, FGFR3, GNAS, INPPL1, PEX7 |
261 | GO:0007274 | 0.01 | 4.32 | 3.31 | 8 | 14 | neuromuscular synaptic transmission | CACNA1A, CHRM1, CHRNB2, CHRNB4, DTNA, EGR3, ETV5, P2RX3 |
262 | GO:0010575 | 0.01 | 4.32 | 3.31 | 8 | 14 | positive regulation of vascular endothelial growth factor production | ARNT, ATF4, C3, FLT4, GATA4, IL1A, ISL1, EIF2AK3 |
263 | GO:0035235 | 0.01 | 4.32 | 3.31 | 8 | 14 | ionotropic glutamate receptor signaling pathway | APP, ATP1A3, PTK2B, GRIA1, GRIA4, GRID1, GRID2, GRIN2A |
264 | GO:0071542 | 0.01 | 4.32 | 3.31 | 8 | 14 | dopaminergic neuron differentiation | PHOX2A, EN1, FOXA2, OTX2, RAC1, RYK, WNT1, PHOX2B |
265 | GO:2000404 | 0.01 | 4.32 | 3.31 | 8 | 14 | regulation of T cell migration | ADAM10, ECM1, ITGA4, S100A7, CCL21, XCL1, ADAM17, TNFSF14 |
266 | GO:2001267 | 0.01 | 4.32 | 3.31 | 8 | 14 | regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | BAX, SMAD3, TRAF2, TRADD, RIPK1, TNFSF10, TNFRSF10B, TNFRSF10A |
267 | GO:0050768 | 0.00 | 4.30 | 7.03 | 17 | 30 | negative regulation of neurogenesis | ASCL2, BMP4, BMPR1A, TSPO, CTNNA1, DRD3, F2, FGFR3, NRG1, NTRK3, PCM1, PTN, SOX11, STAT3, DYNLT1, ARHGEF2, RNF10 |
268 | GO:0031644 | 0.00 | 4.27 | 8.74 | 21 | 37 | regulation of neurological system process | ACPP, CHRNB4, COMT, F2R, GLRA1, GRIN2A, GRM1, HGF, NRG1, HTR2C, IFNG, IL10, NTSR1, P2RX3, PTAFR, PTEN, SLC9A1, TNR, VIP, EIF2AK3, RNF10 |
269 | GO:0021766 | 0.00 | 4.25 | 7.09 | 17 | 30 | hippocampus development | ANXA3, BBS4, CDK6, EMX2, EPHA5, EZH1, KCNA1, OGDH, PTEN, PTPRS, RARA, SRD5A1, SRF, TP73, TSC1, USP9X, ZEB2 |
270 | GO:0051279 | 0.00 | 4.24 | 5.41 | 13 | 23 | regulation of release of sequestered calcium ion into cytosol | ATP1A2, CASQ1, CASQ2, CYBA, DIAPH1, PTK2B, HRC, PLN, PRKCE, PRKD1, PTPN6, RYR2, ATG5 |
271 | GO:0009408 | 0.00 | 4.24 | 5.42 | 13 | 23 | response to heat | CASQ1, DNMT1, EIF2B1, HSPB2, IGF1, IL1R1, P2RX3, PRKCQ, RPS6KB1, TRPV1, EIF2B3, EIF2B2, SOCS3 |
272 | GO:0006284 | 0.00 | 4.22 | 5.44 | 13 | 23 | base-excision repair | ERCC6, FEN1, HMGA1, NTHL1, PCNA, RFC3, RFC4, RFC5, RPA2, RPA3, UNG, PARG, MBD4 |
273 | GO:0007622 | 0.00 | 4.22 | 5.44 | 13 | 23 | rhythmic behavior | AHCY, ALB, CHRNB2, CRH, DRD3, EGR2, GHRHR, KCND2, PTEN, SIX3, SRD5A1, PER3, USP2 |
274 | GO:0042476 | 0.00 | 4.19 | 3.77 | 9 | 16 | odontogenesis | AQP5, AQP6, BGLAP, COL1A1, EDNRA, PAM, PAX9, TUFT1, ZNF22 |
275 | GO:0019369 | 0.00 | 4.18 | 3.78 | 9 | 16 | arachidonic acid metabolic process | ALOX15B, DAGLA, CYP2A6, CYP2A13, CYP2F1, DPEP1, FAAH, GPX1, LTA4H |
276 | GO:0002891 | 0.00 | 4.17 | 3.78 | 9 | 16 | positive regulation of immunoglobulin mediated immune response | C3, CD28, FCER2, HPX, IFNG, XCL1, STAT6, TNFSF4, UNG |
277 | GO:0032026 | 0.00 | 4.17 | 3.78 | 9 | 16 | response to magnesium ion | C3, ENTPD6, KCNA1, KCNC2, KCNJ1, LIPC, SLC34A1, SNCA, FGF23 |
278 | GO:0042104 | 0.00 | 4.17 | 3.78 | 9 | 16 | positive regulation of activated T cell proliferation | CD86, IGF1, IGF2, IL2RA, IL12B, IL18, STAT5B, TNFSF4, TNFSF9 |
279 | GO:0048662 | 0.00 | 4.17 | 3.78 | 9 | 16 | negative regulation of smooth muscle cell proliferation | ANG, COMT, IFNG, IGFBP3, IL12B, ILK, VIP, VIPR2, KLF4 |
280 | GO:0071549 | 0.00 | 4.17 | 3.78 | 9 | 16 | cellular response to dexamethasone stimulus | AGTR2, ARG1, ASS1, CASP9, CRH, DNMT3B, HMBS, SERPINF1, SRD5A1 |
281 | GO:1901381 | 0.00 | 4.17 | 3.78 | 9 | 16 | positive regulation of potassium ion transmembrane transport | DNM2, DPP6, KCNC2, KCNH2, KCNJ2, KCNQ1, AKAP7, AKAP6, AKAP9 |
282 | GO:2000144 | 0.00 | 4.17 | 3.78 | 9 | 16 | positive regulation of DNA-templated transcription, initiation | CREB1, JUN, PSMC1, PSMC2, PSMC3, PSMC4, SRF, HNF1A, FOSL1 |
283 | GO:0035265 | 0.00 | 4.16 | 5.88 | 14 | 25 | organ growth | ACVR2B, ADRA1B, AGTR2, COL9A1, COMP, S1PR1, FGF7, FGFR3, SMAD1, PRKAR1A, RARA, RARB, STC1, SORBS2 |
284 | GO:0007623 | 0.00 | 4.15 | 10.11 | 24 | 43 | circadian rhythm | AHCY, KLF9, CDK4, CRX, DDX5, EGR3, EP300, F7, JUN, JUND, KCND2, LIPC, NTRK2, NTRK3, SERPINE1, PTEN, SIX3, SKP1, SLC9A3, SRD5A1, SREBF1, TYMS, UBB, CUL1 |
285 | GO:0032776 | 0.00 | 4.13 | 5.91 | 14 | 25 | DNA methylation on cytosine | DNMT1, DNMT3B, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HIST1H3F |
286 | GO:0031295 | 0.00 | 4.12 | 8.04 | 19 | 34 | T cell costimulation | CD3D, CD3E, CD3G, CD4, CD5, CD28, CD86, CTLA4, DPP4, EFNB1, FYN, GRB2, PTPN6, RAC1, CCL21, TNFSF4, VAV1, TNFSF14, GRAP2 |
287 | GO:0097553 | 0.00 | 4.12 | 14.42 | 34 | 61 | calcium ion transmembrane import into cytosol | ABL1, ATP1A2, BAX, CALM3, CASQ1, CASQ2, CYBA, DIAPH1, EDNRA, F2, F2R, PTK2B, XCR1, HRC, HTR2C, IL13, ITPR1, NTSR1, P2RX7, PLN, PRKCE, PRKD1, PTPN6, RYR1, RYR2, CCL21, XCL1, SNCA, TRPC1, TRPM2, TRPV1, GSTO1, AKAP6, ATG5 |
288 | GO:0065004 | 0.04 | 4.10 | 2.10 | 5 | 9 | protein-DNA complex assembly | RAD51, RAD51C, RAD51B, RAD51D, XRCC2 |
289 | GO:2000060 | 0.04 | 4.08 | 2.11 | 5 | 9 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process | CAV3, CLU, PTK2B, PTK2, SUMO3 |
290 | GO:0032200 | 0.04 | 4.08 | 2.12 | 5 | 9 | telomere organization | HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H3F |
291 | GO:2000106 | 0.00 | 4.06 | 4.24 | 10 | 18 | regulation of leukocyte apoptotic process | ANXA1, BAX, BTK, CD3G, IL10, P2RX7, PTEN, ADAM17, RAPGEF2, PDCD7 |
292 | GO:0055017 | 0.04 | 4.06 | 2.12 | 5 | 9 | cardiac muscle tissue growth | AGTR2, S1PR1, SMAD1, PRKAR1A, SORBS2 |
293 | GO:0046660 | 0.00 | 4.06 | 15.36 | 36 | 65 | female sex differentiation | ANG, AXL, BAX, BCL2L1, BMP4, BRCA2, CAPN5, CCNE1, CHAT, COL9A3, CTNNA1, FANCF, FANCG, FGF7, FSHB, CENPI, FSHR, GDF9, ICAM1, IDH1, INHA, KDR, KIT, KITLG, PGR, PTPRN, SRD5A1, STAT5B, TYRO3, UBB, UBE3A, NRIP1, FZD4, TP63, EIF2B2, SLIT2 |
294 | GO:0014910 | 0.04 | 4.06 | 2.12 | 5 | 9 | regulation of smooth muscle cell migration | ACE, IGFBP3, ILK, SERPINE1, SLIT2 |
295 | GO:0002042 | 0.00 | 4.05 | 4.25 | 10 | 18 | cell migration involved in sprouting angiogenesis | EGR3, GPLD1, NR4A1, ITGB1, KDR, SRF, NRP1, ITGB1BP1, KLF4, SLIT2 |
296 | GO:0010165 | 0.00 | 4.05 | 4.25 | 10 | 18 | response to X-ray | ANXA1, BRCA2, CDKN1A, DNM2, ERCC6, RAD51, TP73, XRCC2, XRCC5, TP63 |
297 | GO:0014808 | 0.00 | 4.05 | 4.25 | 10 | 18 | release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | ATP1A2, CALM3, CASQ1, CASQ2, HRC, PLN, RYR1, RYR2, GSTO1, AKAP6 |
298 | GO:0045987 | 0.00 | 4.05 | 4.25 | 10 | 18 | positive regulation of smooth muscle contraction | ABAT, ADRA1B, CHRM3, CTTN, F2R, OXTR, PTAFR, PTGS1, SRF, TACR3 |
299 | GO:0060306 | 0.00 | 4.05 | 4.25 | 10 | 18 | regulation of membrane repolarization | CASQ2, CAV3, KCNH2, KCNJ2, KCNQ1, SCN4B, SCN5A, AKAP7, AKAP6, AKAP9 |
300 | GO:0086019 | 0.04 | 4.05 | 2.12 | 5 | 9 | cell-cell signaling involved in cardiac conduction | CXADR, KCNQ1, SCN4B, NUP155, HCN4 |
301 | GO:0001502 | 0.04 | 4.05 | 2.13 | 5 | 9 | cartilage condensation | BMP1, COL11A1, CTGF, FGF4, SOX9 |
302 | GO:0002719 | 0.04 | 4.05 | 2.13 | 5 | 9 | negative regulation of cytokine production involved in immune response | ANGPT1, BST2, IFNA2, IL10, XCL1 |
303 | GO:0007617 | 0.04 | 4.05 | 2.13 | 5 | 9 | mating behavior | APLP2, APP, DRD5, HEXB, PTEN |
304 | GO:0009312 | 0.04 | 4.05 | 2.13 | 5 | 9 | oligosaccharide biosynthetic process | FUT8, B4GALT1, MGAT2, B3GALT2, MPDU1 |
305 | GO:0009650 | 0.04 | 4.05 | 2.13 | 5 | 9 | UV protection | CAT, ERCC3, ERCC4, FEN1, GPX1 |
306 | GO:0010613 | 0.04 | 4.05 | 2.13 | 5 | 9 | positive regulation of cardiac muscle hypertrophy | IGF1, SLC9A1, TRPC3, PDE5A, AKAP6 |
307 | GO:0010919 | 0.04 | 4.05 | 2.13 | 5 | 9 | regulation of inositol phosphate biosynthetic process | PTK2B, HRH1, NTSR1, PTAFR, SNCA |
308 | GO:0021781 | 0.04 | 4.05 | 2.13 | 5 | 9 | glial cell fate commitment | ASCL1, NRG1, SOX9, TAL1, OLIG2 |
309 | GO:0022038 | 0.04 | 4.05 | 2.13 | 5 | 9 | corpus callosum development | LPAR1, EPHB2, EPHB3, PTPRS, RYK |
310 | GO:0032516 | 0.04 | 4.05 | 2.13 | 5 | 9 | positive regulation of phosphoprotein phosphatase activity | AGTR2, CALM3, ITGA1, PPP1R12A, AKAP6 |
311 | GO:0032717 | 0.04 | 4.05 | 2.13 | 5 | 9 | negative regulation of interleukin-8 production | ANXA1, BCL3, BPI, IL10, KLF4 |
312 | GO:0033604 | 0.04 | 4.05 | 2.13 | 5 | 9 | negative regulation of catecholamine secretion | ABAT, AGTR2, CNR1, CRH, PTGS1 |
313 | GO:0042026 | 0.04 | 4.05 | 2.13 | 5 | 9 | protein refolding | DNAJB2, HSPA6, SNRNP70, DNAJC7, BAG5 |
314 | GO:0043092 | 0.04 | 4.05 | 2.13 | 5 | 9 | L-amino acid import | ARG1, ATP1A2, KCNJ10, NTSR1, SLC6A5 |
315 | GO:0045899 | 0.04 | 4.05 | 2.13 | 5 | 9 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly | CREB1, PSMC1, PSMC2, PSMC3, PSMC4 |
316 | GO:0045989 | 0.04 | 4.05 | 2.13 | 5 | 9 | positive regulation of striated muscle contraction | ATP1A1, ATP2A1, CTGF, KCNQ1, GSTO1 |
317 | GO:0051580 | 0.04 | 4.05 | 2.13 | 5 | 9 | regulation of neurotransmitter uptake | ATP1A2, DRD3, GFAP, RAB3B, SNCA |
318 | GO:0055098 | 0.04 | 4.05 | 2.13 | 5 | 9 | response to low-density lipoprotein particle | ABCA1, CD9, CD36, F3, ITGB1 |
319 | GO:0070230 | 0.04 | 4.05 | 2.13 | 5 | 9 | positive regulation of lymphocyte apoptotic process | BAX, IL10, IDO1, P2RX7, PDCD7 |
320 | GO:1900409 | 0.04 | 4.05 | 2.13 | 5 | 9 | positive regulation of cellular response to oxidative stress | SFPQ, SNCA, TRPM2, RGN, HDAC6 |
321 | GO:2001241 | 0.04 | 4.05 | 2.13 | 5 | 9 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | BAX, CTNNA1, DAPK3, PPP2R1A, PPP2R1B |
322 | GO:0045471 | 0.00 | 4.01 | 18.91 | 44 | 80 | response to ethanol | ABAT, ALAD, ATP5G3, BAD, BGLAP, CAT, CCNE1, CDK2, CDO1, CHAT, CHRNB2, CNR1, CRH, CRHBP, DBH, DNMT1, PTK2B, FYN, GLRA1, GOT2, GRIN2A, HMGCR, HMGCS2, ICAM1, IGF2, IL13, KCNC2, MGMT, NTRK3, OXCT1, PENK, PRKAA1, PRKCE, PTEN, RARA, RPS6KB1, RXRA, S100A8, SLC2A4, SPARC, STAT3, STAT5B, TYMS, PSMD14 |
323 | GO:0006953 | 0.00 | 4.00 | 6.85 | 16 | 29 | acute-phase response | ASS1, CNR1, CRP, F2, FGA, HP, IL1A, IL1RN, INS, ITIH4, ORM2, SAA4, STAT3, STAT5B, TRPV1, CD163 |
324 | GO:0051283 | 0.00 | 4.00 | 14.18 | 33 | 60 | negative regulation of sequestering of calcium ion | ABL1, ATP1A2, BAX, CALM3, CASQ1, CASQ2, CYBA, DIAPH1, EDNRA, F2, F2R, PTK2B, XCR1, HRC, HTR2C, IL13, ITPR1, NTSR1, P2RX7, PLN, PRKCE, PRKD1, PTPN6, RYR1, RYR2, CCL21, XCL1, SNCA, TRPC1, TRPV1, GSTO1, AKAP6, ATG5 |
325 | GO:0044344 | 0.02 | 3.98 | 2.55 | 6 | 11 | cellular response to fibroblast growth factor stimulus | CD44, COL1A1, CPS1, EGR3, SNCA, ITGB1BP1 |
326 | GO:0031018 | 0.00 | 3.98 | 4.72 | 11 | 20 | endocrine pancreas development | ANXA1, CLU, NR5A2, FOXA2, HNF4G, ONECUT1, IAPP, INS, SOX9, EIF2AK3, ONECUT2 |
327 | GO:0021954 | 0.00 | 3.97 | 4.72 | 11 | 20 | central nervous system neuron development | ASCL1, GNAQ, HPRT1, NTRK2, OGDH, RAC1, RAC3, CNTN2, UBB, NRP1, RAPGEF2 |
328 | GO:0045429 | 0.00 | 3.96 | 4.73 | 11 | 20 | positive regulation of nitric oxide biosynthetic process | AGTR2, ASS1, CLU, DNM2, PTK2B, ICAM1, IFNG, INS, P2RX4, TRPV1, KLF4 |
329 | GO:0051930 | 0.00 | 3.96 | 4.73 | 11 | 20 | regulation of sensory perception of pain | ACPP, COMT, F2R, GRIN2A, GRM1, IL10, NTSR1, P2RX3, PTAFR, SLC9A1, VIP |
330 | GO:0051592 | 0.00 | 3.96 | 7.30 | 17 | 31 | response to calcium ion | ANXA5, ANXA11, BAD, ENTPD6, DUSP1, PTK2B, FGA, GDI1, LIPC, P2RX7, PENK, SPARC, TRPC1, TRPC3, SLC25A12, PDCD6, SLC25A13 |
331 | GO:0014823 | 0.00 | 3.95 | 7.33 | 17 | 31 | response to activity | ALAD, ANGPT2, BGLAP, CAT, CREB1, DNMT1, DNMT3B, IGF1, IL10, ITGB1, OXCT1, PCK1, PRKAA1, PTN, RYR2, SRD5A1, UQCRC1 |
332 | GO:0032496 | 0.00 | 3.94 | 22.06 | 51 | 94 | response to lipopolysaccharide | ADH5, ALAD, ATP4B, BCR, CASP9, TNFRSF8, CHUK, CNP, CNR1, COMT, CPS1, DCN, DNMT1, EDNRA, F2R, F3, CXCL3, IGF1, IL10RA, IL12RB2, IL13, IDO1, JUN, JUND, KCNJ8, P2RX7, PENK, PF4V1, PTGER1, PTGER2, RPS6KB1, S100A7, S100A8, CXCL6, CXCL5, SELE, SELP, SLPI, SNCA, SPARC, STAT5B, ADAM17, TNFRSF1A, SCGB1A1, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, SOCS3, NR1H4, IL18BP |
333 | GO:0051291 | 0.00 | 3.93 | 10.36 | 24 | 44 | protein heterooligomerization | ACVRL1, BIRC3, CHRNB2, CHRNB4, COL1A1, COL6A1, COL6A2, CLDN3, CTNNA1, GLRA1, HBA2, HBE1, ILK, KCNC2, P2RX1, PPP5C, PRKAA1, STXBP3, TRAF2, TSC1, OGT, TRADD, RIPK1, CLDN1 |
334 | GO:0006937 | 0.00 | 3.93 | 21.27 | 49 | 90 | regulation of muscle contraction | ABAT, ADRA1B, ANXA6, ATP1A1, ATP1A2, ATP2A1, CALM3, CASQ1, CASQ2, CAV3, CHRM1, CHRM3, CHRNB4, CNN1, CTGF, DAPK3, CTTN, F2R, FLT1, GATA4, GHSR, HRC, KCNA1, KCNJ2, KCNQ1, SMAD7, PPP1R12B, OXTR, P2RX1, P2RX4, PDE4B, PLN, PTAFR, PTGS1, RYR2, SCN5A, SLC8A3, SLC9A1, SRF, STC1, TACR3, TNNC2, TNNC1, TNNI2, TNNI3, SUMO1, PDE5A, GSTO1, HCN4 |
335 | GO:0002065 | 0.00 | 3.92 | 5.18 | 12 | 22 | columnar/cuboidal epithelial cell differentiation | ARNTL, BAD, BMP4, CDK6, IL13, RARA, RARB, RFX3, RHEB, RXRA, TP63, CLOCK |
336 | GO:0008630 | 0.00 | 3.91 | 7.78 | 18 | 33 | intrinsic apoptotic signaling pathway in response to DNA damage | ABL1, BAD, BAX, BCL2A1, BCL2L1, BOK, CASP9, CLU, EPHA2, ERCC6, HIC1, RPS3, SNAI1, TNFRSF1A, TNFRSF1B, TPT1, XPA, BCL2L11 |
337 | GO:0070252 | 0.00 | 3.91 | 10.40 | 24 | 44 | actin-mediated cell contraction | ATP1A1, ATP1A2, CAV3, EMP2, GATA4, KCNH2, KCNJ2, KCNQ1, PDE4B, PLN, RYR2, SCN4B, SCN5A, SLC9A1, STC1, TNNC2, TNNC1, TNNI2, TNNI3, TPM2, SUMO1, VIL1, VIM, NUP155 |
338 | GO:0001541 | 0.00 | 3.91 | 7.79 | 18 | 33 | ovarian follicle development | ANG, BAX, BCL2L1, BMP4, CAPN5, CCNE1, CHAT, CTNNA1, FANCF, FANCG, FGF7, ICAM1, INHA, KDR, KIT, KITLG, UBE3A, EIF2B2 |
339 | GO:1900373 | 0.03 | 3.90 | 2.59 | 6 | 11 | positive regulation of purine nucleotide biosynthetic process | GUCA1A, GUCA2A, GUCA2B, RCVRN, STAT3, GUCA1C |
340 | GO:0061053 | 0.03 | 3.90 | 2.59 | 6 | 11 | somite development | IHH, RAD51B, RBBP6, SOX11, WNT1, WNT11 |
341 | GO:0050798 | 0.03 | 3.90 | 2.59 | 6 | 11 | activated T cell proliferation | ABL1, CLC, FYN, ITGAD, PRKAR1A, SATB1 |
342 | GO:0070482 | 0.00 | 3.90 | 20.41 | 47 | 87 | response to oxygen levels | ABAT, AHCY, ALAD, ALAS2, ANG, ANGPT2, APAF1, ASCL2, CAT, CDK4, CDKN1A, CHAT, CHRNB2, COL1A1, CLDN3, CREB1, CTGF, DPP4, EDNRA, ERCC3, ETS1, PTK2B, FLT1, HMBS, IGF1, ITPR1, LIPC, SMAD3, OXTR, P2RX3, PAM, PENK, PRKCQ, PYGM, RAF1, RYR1, RYR2, SCNN1B, CX3CL1, SHC1, SRF, STAT5B, ADAM17, HSP90B1, USF1, SOCS3, PDLIM1 |
343 | GO:0000272 | 0.00 | 3.89 | 5.20 | 12 | 22 | polysaccharide catabolic process | ADRA1B, CALM3, CPS1, G6PC, GAA, INS, PHKA2, PHKB, PHKG1, PYGB, PYGM, MGAM |
344 | GO:0014855 | 0.00 | 3.89 | 5.20 | 12 | 22 | striated muscle cell proliferation | ANGPT1, CCNB1, CXADR, GATA4, GATA6, NRG1, RBPJ, KCNK2, SMAD1, PRKAR1A, STAT3, TP73 |
345 | GO:0033628 | 0.00 | 3.89 | 5.20 | 12 | 22 | regulation of cell adhesion mediated by integrin | DPP4, EFNA1, EPHA2, EPHA8, HRG, SERPINE1, PTK2, PTPN6, RAC3, CCL21, ITGB1BP1, PIEZO1 |
346 | GO:0038083 | 0.00 | 3.89 | 5.20 | 12 | 22 | peptidyl-tyrosine autophosphorylation | ABL1, ABL2, BLK, BTK, ACE, PTK2B, FGR, FYN, IGF1R, KDR, PTK2, AATK |
347 | GO:0000132 | 0.03 | 3.89 | 2.60 | 6 | 11 | establishment of mitotic spindle orientation | CENPA, NUMA1, DYNLT1, ARHGEF2, ZW10, SPRY1 |
348 | GO:0002724 | 0.03 | 3.89 | 2.60 | 6 | 11 | regulation of T cell cytokine production | CLC, IFNA2, XCL1, TRAF2, TNFSF4, FZD5 |
349 | GO:0002888 | 0.03 | 3.89 | 2.60 | 6 | 11 | positive regulation of myeloid leukocyte mediated immunity | C3, FGR, IL13, PTAFR, VAMP8, GAB2 |
350 | GO:0006298 | 0.03 | 3.89 | 2.60 | 6 | 11 | mismatch repair | ABL1, PCNA, RPA2, RPA3, TP73, EXO1 |
351 | GO:0007141 | 0.03 | 3.89 | 2.60 | 6 | 11 | male meiosis I | BRCA2, BRDT, ING2, RAD51C, UBB, REC8 |
352 | GO:0020027 | 0.03 | 3.89 | 2.60 | 6 | 11 | hemoglobin metabolic process | ADD1, ALAS2, CAT, HPX, INHA, KLF4 |
353 | GO:0042762 | 0.03 | 3.89 | 2.60 | 6 | 11 | regulation of sulfur metabolic process | BHMT, COMT, PDK4, SNCA, SP1, PDHX |
354 | GO:0043537 | 0.03 | 3.89 | 2.60 | 6 | 11 | negative regulation of blood vessel endothelial cell migration | ACVRL1, AGTR2, ANGPT2, HRG, ITGB1BP1, KLF4 |
355 | GO:0051000 | 0.03 | 3.89 | 2.60 | 6 | 11 | positive regulation of nitric-oxide synthase activity | AGTR2, CALM3, DHFR, PTK2B, FCER2, INS |
356 | GO:0055026 | 0.03 | 3.89 | 2.60 | 6 | 11 | negative regulation of cardiac muscle tissue development | CAV3, CXADR, FGF3, KCNK2, TP73, CTDP1 |
357 | GO:0060307 | 0.03 | 3.89 | 2.60 | 6 | 11 | regulation of ventricular cardiac muscle cell membrane repolarization | CAV3, KCNH2, KCNQ1, SCN4B, SCN5A, AKAP9 |
358 | GO:0060561 | 0.03 | 3.89 | 2.60 | 6 | 11 | apoptotic process involved in morphogenesis | BAX, FGF4, B4GALT1, PPP2R1B, FZD5, BCL2L11 |
359 | GO:0070293 | 0.03 | 3.89 | 2.60 | 6 | 11 | renal absorption | KCNJ1, KCNQ1, SGK1, HNF1A, AKR1C3, SLC9A3R1 |
360 | GO:0070875 | 0.03 | 3.89 | 2.60 | 6 | 11 | positive regulation of glycogen metabolic process | ADRA1B, IGF1, IGF2, INS, DYRK2, EPM2AIP1 |
361 | GO:0072148 | 0.03 | 3.89 | 2.60 | 6 | 11 | epithelial cell fate commitment | FGFR3, GATA4, RBPJ, RARA, NR2F2, NRP1 |
362 | GO:1902176 | 0.03 | 3.89 | 2.60 | 6 | 11 | negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | GPX1, HSPB1, INS, SOD2, BAG5, TRAP1 |
363 | GO:0002712 | 0.00 | 3.84 | 5.67 | 13 | 24 | regulation of B cell mediated immunity | BTK, C3, CD28, FCER2, HPX, IFNG, IL10, PTPN6, XCL1, STAT6, TNFSF4, UNG, IL27RA |
364 | GO:0015991 | 0.00 | 3.84 | 5.67 | 13 | 24 | ATP hydrolysis coupled proton transport | ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP4A, ATP5G2, ATP5G3, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, ATP6V0D1 |
365 | GO:1902743 | 0.00 | 3.84 | 5.67 | 13 | 24 | regulation of lamellipodium organization | DNM2, EPHA2, HRG, RAC1, RAC2, FSCN1, CLRN1, VIL1, WNT1, ARHGEF7, SLIT2, ARPC2, WASF2 |
366 | GO:0071375 | 0.01 | 3.83 | 3.45 | 8 | 15 | cellular response to peptide hormone stimulus | ANXA5, CRHBP, CYP11B1, GNRHR, NR4A1, RANGAP1, WNT1, AKAP1 |
367 | GO:0097529 | 0.02 | 3.81 | 3.05 | 7 | 13 | myeloid leukocyte migration | CX3CR1, PTK2B, KIT, SFTPD, STAT5B, VEGFB, ARHGEF5 |
368 | GO:0002687 | 0.02 | 3.80 | 3.06 | 7 | 13 | positive regulation of leukocyte migration | ICAM1, KITLG, PTAFR, SELE, SELP, MADCAM1, TNFRSF18 |
369 | GO:0030574 | 0.00 | 3.80 | 9.22 | 21 | 39 | collagen catabolic process | ADAM10, COL1A1, COL4A3, COL4A5, COL4A6, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, COL11A1, COL15A1, CTSK, FAP, ITGB1, PEPD, ADAM17, ADAM15, ADAMTS3, ADAMTS2 |
370 | GO:1903050 | 0.00 | 3.79 | 9.65 | 22 | 41 | regulation of proteolysis involved in cellular protein catabolic process | CAV3, PTK2B, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMD2, PSMD3, PSMD4, PSMD7, PTK2, SKP1, SUMO3, UBE3A, WNT1, CUL1, RGN |
371 | GO:0001829 | 0.02 | 3.78 | 3.07 | 7 | 13 | trophectodermal cell differentiation | BYSL, CDX2, CNOT2, SP1, SRF, CUL3, HAND1 |
372 | GO:0001953 | 0.02 | 3.78 | 3.07 | 7 | 13 | negative regulation of cell-matrix adhesion | ACVRL1, ARHGAP6, SERPINE1, PTEN, ADAM15, ITGB1BP1, SEMA3E |
373 | GO:0009954 | 0.02 | 3.78 | 3.07 | 7 | 13 | proximal/distal pattern formation | EN1, HOXC10, HOXC11, HOXD9, HOXD10, SIX3, TP63 |
374 | GO:0010762 | 0.02 | 3.78 | 3.07 | 7 | 13 | regulation of fibroblast migration | ARHGAP4, PRKCE, RAC1, SDC4, ARHGEF7, ITGB1BP1, BAG4 |
375 | GO:0015697 | 0.02 | 3.78 | 3.07 | 7 | 13 | quaternary ammonium group transport | ACACB, CPT1B, CPT2, SLC22A1, SLC22A3, SLC22A2, SLC22A5 |
376 | GO:0019835 | 0.02 | 3.78 | 3.07 | 7 | 13 | cytolysis | ALB, BAD, C7, GPLD1, GZMH, HPRT1, P2RX7 |
377 | GO:0031000 | 0.02 | 3.78 | 3.07 | 7 | 13 | response to caffeine | CASQ2, DNMT1, DNMT3B, IGF1, PRKAA1, RYR1, RYR2 |
378 | GO:0035855 | 0.02 | 3.78 | 3.07 | 7 | 13 | megakaryocyte development | EP300, KIT, PIP4K2A, PTPN6, SRF, TAL1, WASF2 |
379 | GO:0060260 | 0.02 | 3.78 | 3.07 | 7 | 13 | regulation of transcription initiation from RNA polymerase II promoter | CREB1, PSMC1, PSMC2, PSMC3, PSMC4, SRF, HNF1A |
380 | GO:0060397 | 0.02 | 3.78 | 3.07 | 7 | 13 | JAK-STAT cascade involved in growth hormone signaling pathway | CSH1, GH2, PTPN6, STAT3, STAT5B, ADAM17, SOCS3 |
381 | GO:0090077 | 0.02 | 3.78 | 3.07 | 7 | 13 | foam cell differentiation | ABCA1, AGTR1, ALOX15B, CD36, CRP, ITGAV, NR1H2 |
382 | GO:0051384 | 0.00 | 3.77 | 14.08 | 32 | 60 | response to glucocorticoid | ABCA3, ACADS, ALAD, ANXA3, BAD, BCHE, BGLAP, BMP4, C3, CDO1, CPS1, DUSP1, GHRHR, HNMT, IGF1, IL1RN, IL10, LCAT, LIPC, PAM, PTAFR, RPS6KB1, RXRA, SHC1, SLC9A3, SPARC, TAT, TYMS, SCGB1A1, SOCS3, SLIT2, PDCD7 |
383 | GO:1903779 | 0.00 | 3.75 | 10.16 | 23 | 43 | regulation of cardiac conduction | ATP1A1, ATP1A2, ATP1A3, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, CALM3, CASQ1, CASQ2, CXADR, HRC, ITPR1, KCNJ11, FXYD3, PLN, RYR1, RYR2, SLC8A3, TNNI3, TRPC1, ABCC9 |
384 | GO:0030183 | 0.00 | 3.73 | 10.62 | 24 | 45 | B cell differentiation | ABL1, BAX, BCL3, CR2, EP300, PTK2B, HHEX, ONECUT1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, RBPJ, IL10, ITGA4, ITGB1, KIT, RAG1, RAG2, ADAM17, TPD52, FZD9 |
385 | GO:0006977 | 0.00 | 3.72 | 10.63 | 24 | 45 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, UBB, CRADD, PSMF1, PSME3, PSMD14 |
386 | GO:1902400 | 0.00 | 3.72 | 10.63 | 24 | 45 | intracellular signal transduction involved in G1 DNA damage checkpoint | CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, UBB, CRADD, PSMF1, PSME3, PSMD14 |
387 | GO:0070509 | 0.00 | 3.72 | 18.67 | 42 | 79 | calcium ion import | ABL1, ATP1A2, ATP2A1, BAX, CALM3, CASQ1, CASQ2, CAV3, CRH, CYBA, DIAPH1, EDNRA, F2, F2R, PTK2B, GCG, XCR1, HRC, HTR2C, IL13, ITPR1, NTSR1, P2RX7, PLN, PRKCE, PRKD1, PTPN6, RYR1, RYR2, CCL21, XCL1, SLC8A3, SNCA, SPINK1, STC1, TRPC1, TRPC4, TRPM2, TRPV1, GSTO1, AKAP6, ATG5 |
388 | GO:0048857 | 0.01 | 3.72 | 3.54 | 8 | 15 | neural nucleus development | ALDH1A3, PHOX2A, ASCL1, CACNA1A, CHRNB2, KCNC2, PHOX2B, SLC4A7 |
389 | GO:0008542 | 0.00 | 3.71 | 7.09 | 16 | 30 | visual learning | ABL2, ADRA1B, APP, ATP1A2, ATP1A3, CHRNB2, CREB1, CTNS, DBH, DRD3, GRIN2A, HMGCR, HRH1, ITGB1, KIT, SGK1 |
390 | GO:0002026 | 0.01 | 3.70 | 3.54 | 8 | 15 | regulation of the force of heart contraction | ADRA1B, ATP1A1, ATP1A2, GAA, IFNG, PLN, RYR2, SLC9A1 |
391 | GO:0035767 | 0.01 | 3.70 | 3.54 | 8 | 15 | endothelial cell chemotaxis | EGR3, FGF4, NR4A1, HRG, HSPB1, KDR, PRKD1, NRP1 |
392 | GO:0051894 | 0.01 | 3.70 | 3.54 | 8 | 15 | positive regulation of focal adhesion assembly | HRG, KDR, SMAD3, PTPRJ, RAC1, SDC4, TSC1, ITGB1BP1 |
393 | GO:0043200 | 0.00 | 3.69 | 7.55 | 17 | 32 | response to amino acid | ALAD, ARG1, ASCL1, BAD, BCHE, CDO1, CHUK, CPS1, CREB1, CTGF, HMBS, ICAM1, LIPC, MGMT, PTN, RPS6KB1, TYMS |
394 | GO:0097192 | 0.00 | 3.66 | 8.02 | 18 | 34 | extrinsic apoptotic signaling pathway in absence of ligand | BAD, BCL2A1, BCL2L1, BOK, CASP9, CX3CR1, DCC, EYA2, FYN, NRG1, IGF1, IL1A, ITGAV, KITLG, CX3CL1, RIPK1, BAG3, BCL2L11 |
395 | GO:0071345 | 0.00 | 3.66 | 6.59 | 15 | 29 | cellular response to cytokine stimulus | ALAD, ARG1, CD86, DPYSL3, ETV3, FGA, HCLS1, HMBS, IL13, IMPDH2, ITGA4, RPL3, SELPLG, FGF23, AKAP6 |
396 | GO:0046530 | 0.00 | 3.66 | 8.04 | 18 | 34 | photoreceptor cell differentiation | BBS4, PRDM1, CRX, GNAT1, GNAT2, GNGT1, IHH, NTRK2, OTX2, PRKCI, PTN, RPGR, SOX9, STAT3, TULP1, SLC4A7, IFT140, NR2E3 |
397 | GO:0006919 | 0.00 | 3.65 | 8.49 | 19 | 36 | activation of cysteine-type endopeptidase activity involved in apoptotic process | APAF1, BAD, BOK, CASP9, COL4A3, CTSH, F2R, F3, HIP1, P2RX1, S100A8, S100A9, SNCA, CRADD, EIF2AK3, TNFSF15, CASP8AP2, PDCD6, BCL2L11 |
398 | GO:0002639 | 0.01 | 3.65 | 4.02 | 9 | 17 | positive regulation of immunoglobulin production | CD28, CD37, HPX, IFNG, IL13, XCL1, STAT6, TNFSF4, UNG |
399 | GO:0010712 | 0.01 | 3.65 | 4.02 | 9 | 17 | regulation of collagen metabolic process | BMP4, CTGF, F2, F2R, FAP, IHH, ITGB1, CIITA, SERPINB7 |
400 | GO:0030811 | 0.01 | 3.65 | 4.02 | 9 | 17 | regulation of nucleotide catabolic process | ARNT, IGF1, INS, P2RX7, PGAM1, PRKAA1, PRKAG1, STAT3, OGT |
401 | GO:0032309 | 0.01 | 3.65 | 4.02 | 9 | 17 | icosanoid secretion | AGTR2, ANXA1, ACE, DRD3, NTSR1, P2RX4, P2RX7, P2RY2, ABCC4 |
402 | GO:0045003 | 0.01 | 3.65 | 4.02 | 9 | 17 | double-strand break repair via synthesis-dependent strand annealing | BARD1, BRCA2, RAD51, RAD51C, RAD51B, RAD51D, XRCC2, EXO1, RAD50 |
403 | GO:0046579 | 0.01 | 3.65 | 4.02 | 9 | 17 | positive regulation of Ras protein signal transduction | LPAR1, F2R, NRG1, IGF1, KITLG, RAC1, SHOC2, DGKI, GPR55 |
404 | GO:0046688 | 0.01 | 3.65 | 4.02 | 9 | 17 | response to copper ion | BAX, ICAM1, IL1A, LCAT, LIPC, PAM, S100A13, SNCA, SORD |
405 | GO:0048016 | 0.01 | 3.65 | 4.02 | 9 | 17 | inositol phosphate-mediated signaling | RCAN1, NRG1, HRH1, IGF1, ITPR1, SLC9A1, SLC12A1, AKAP6, RCAN2 |
406 | GO:1903053 | 0.01 | 3.65 | 4.02 | 9 | 17 | regulation of extracellular matrix organization | ABL1, ABL2, DPP4, ETS1, FAP, GPX1, SMAD3, FSCN1, SOX9 |
407 | GO:0001666 | 0.00 | 3.65 | 19.26 | 43 | 82 | response to hypoxia | ABAT, AHCY, ALAD, ALAS2, ANG, ANGPT2, APAF1, ASCL2, CAT, CHAT, CHRNB2, CLDN3, CREB1, DNMT3B, DPP4, EDNRA, ERCC3, ETS1, PTK2B, FLT1, HMBS, IGF1, ITPR1, LIPC, SMAD3, P2RX3, PAM, PENK, PRKCQ, PYGM, RAF1, RYR1, RYR2, SCNN1B, CX3CL1, SHC1, SRF, STAT5B, ADAM17, HSP90B1, USF1, SOCS3, PDLIM1 |
408 | GO:0030155 | 0.00 | 3.63 | 6.20 | 14 | 27 | regulation of cell adhesion | ADAM10, ARHGDIB, S1PR1, ICAM1, KNG1, LAMA3, LAMA4, PPP1R12A, PPP2R1A, PRKX, SIPA1, SOX9, SRF, NUAK1 |
409 | GO:0010939 | 0.01 | 3.60 | 4.49 | 10 | 19 | regulation of necrotic cell death | BIRC3, TSPO, TRAF2, UBB, TRADD, RIPK1, TNFSF10, TNFRSF10B, TNFRSF10A, ARHGEF2 |
410 | GO:0042462 | 0.01 | 3.60 | 4.49 | 10 | 19 | eye photoreceptor cell development | BBS4, PRDM1, GNAT1, GNAT2, GNGT1, NTRK2, PRKCI, RPGR, TULP1, NR2E3 |
411 | GO:0045661 | 0.01 | 3.60 | 4.49 | 10 | 19 | regulation of myoblast differentiation | BMP4, FLOT2, FLT3LG, IGFBP3, IL18, ILK, SOX9, NR2C2, TNFSF14, CXCL14 |
412 | GO:0055010 | 0.01 | 3.60 | 4.49 | 10 | 19 | ventricular cardiac muscle tissue morphogenesis | COL11A1, NRG1, RBPJ, ISL1, SMAD7, RXRA, RYR2, TNNC1, TNNI3, HAND1 |
413 | GO:1901571 | 0.01 | 3.60 | 4.49 | 10 | 19 | fatty acid derivative transport | AGTR2, ANXA1, ACE, DRD3, NTSR1, P2RX4, P2RX7, P2RY2, SLCO2A1, ABCC4 |
414 | GO:2000352 | 0.01 | 3.60 | 4.49 | 10 | 19 | negative regulation of endothelial cell apoptotic process | ABL1, ABL2, ANGPT1, KRIT1, FGA, ICAM1, IL13, KDR, SERPINE1, SCG2 |
415 | GO:0071560 | 0.00 | 3.60 | 4.93 | 11 | 21 | cellular response to transforming growth factor beta stimulus | APAF1, ARG1, COL1A1, CX3CR1, DNMT1, FYN, PENK, XCL1, SOX9, CLEC3B, STK16 |
416 | GO:0051092 | 0.00 | 3.59 | 14.89 | 33 | 63 | positive regulation of NF-kappaB transcription factor activity | ALK, BTK, CAMK2A, CAT, CHUK, CLU, CTH, EDA, ICAM1, INS, IRAK1, IRAK2, LTF, PRKCI, PRKD1, PRKCQ, PSMA6, RPS3, S100A8, S100A9, S100A12, TRAF1, TRAF2, UBB, TRIM25, IKBKG, TRADD, RIPK1, RIPK2, RPS6KA4, TNFSF18, ARHGEF2, CLOCK |
417 | GO:0007131 | 0.00 | 3.57 | 4.96 | 11 | 21 | reciprocal meiotic recombination | ERCC4, RAD21, RAD51, RAD51C, RAD51B, RAD51D, TOP2A, TOP2B, XRCC2, REC8, RAD50 |
418 | GO:0007190 | 0.00 | 3.57 | 4.96 | 11 | 21 | activation of adenylate cyclase activity | AVPR2, CALM3, DRD5, EDNRA, FSHR, GHRHR, GNAS, NTRK2, P2RY11, RAF1, VIPR2 |
419 | GO:0009268 | 0.00 | 3.57 | 4.96 | 11 | 21 | response to pH | STS, CLCN7, GJA3, GPLD1, INSRR, KCNJ8, PAM, PCK1, SERPINF1, SLC9A1, TRPV1 |
420 | GO:0046686 | 0.00 | 3.57 | 4.96 | 11 | 21 | response to cadmium ion | ALAD, ARG1, CAT, CDK2, CYB5A, PCNA, PPP5C, SLC34A1, SORD, SPARC, AKR1C3 |
421 | GO:0051238 | 0.00 | 3.55 | 17.72 | 39 | 75 | sequestering of metal ion | ABL1, ATP1A2, BAX, CALM3, CASQ1, CASQ2, CYBA, DIAPH1, EDNRA, F2, F2R, PTK2B, XCR1, HRC, HTR2C, IL13, ITPR1, NTSR1, P2RX7, PLN, PRKCE, PRKD1, PTPN6, RYR1, RYR2, S100A7, S100A8, S100A9, CCL21, XCL1, SNCA, HSP90B1, TRPC1, TRPV1, SLC30A2, AP3D1, GSTO1, AKAP6, ATG5 |
422 | GO:0071869 | 0.00 | 3.54 | 5.44 | 12 | 23 | response to catecholamine | ABL1, APP, DNM2, DRD5, GNAS, KCNQ1, PDE4B, PENK, RYR2, SLC9A1, SNCA, SRD5A1 |
423 | GO:0051349 | 0.00 | 3.52 | 5.90 | 13 | 25 | positive regulation of lyase activity | AVPR2, CALM3, DRD5, EDNRA, FSHR, GHRHR, GNAS, NTRK2, P2RY11, RAF1, VIP, VIPR2, WFS1 |
424 | GO:0018108 | 0.00 | 3.52 | 17.26 | 38 | 74 | peptidyl-tyrosine phosphorylation | ALK, APLP2, APP, AXL, BCR, CLK1, CLK3, EPHA2, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, F2R, EFEMP1, FLT1, FLT4, HRG, IL12RB2, INSRR, MAP3K11, NTRK2, NTRK3, PPP2R1A, PRKCE, PTPN6, RAP2B, RYK, SHC1, SPINK1, TTK, TYRO3, DYRK2, STK16, DYRK4, BAZ1B, DYRK1B, ABI2 |
425 | GO:0042551 | 0.00 | 3.52 | 5.91 | 13 | 25 | neuron maturation | ABL2, APP, CLN5, EPHA8, GNAQ, NRCAM, OPA1, RAC1, RAC3, RB1, CNTN2, PICK1, IRX5 |
426 | GO:0030195 | 0.00 | 3.50 | 6.38 | 14 | 27 | negative regulation of blood coagulation | ABAT, ANXA5, APOH, F2, FAP, FGA, GP1BA, HRG, KLKB1, KNG1, SERPINE1, PROC, USF1, VTN |
427 | GO:0010517 | 0.00 | 3.49 | 14.18 | 31 | 60 | regulation of phospholipase activity | ABL1, ABL2, AGTR1, ANG, ANXA1, ARHGAP6, ARL1, AVPR1B, BICD1, CALM3, CREB1, LPAR1, EDNRA, FGFR3, FLT1, GNA15, GNAQ, ITPR1, KIT, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PTAFR, SELE, SNCA, S1PR4, GPR55 |
428 | GO:0008344 | 0.00 | 3.49 | 6.84 | 15 | 29 | adult locomotory behavior | APP, ARCN1, ATP1A2, ATP1A3, CLCN3, CNP, DNM1, FOXA2, HOXD9, HOXD10, NTF4, NTSR1, SNCA, TBCE, TSC1 |
429 | GO:0071377 | 0.00 | 3.48 | 6.85 | 15 | 29 | cellular response to glucagon stimulus | ARG1, ASS1, CPS1, GCG, GCGR, GNAS, GNG3, GNG10, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, GLP2R |
430 | GO:0031638 | 0.00 | 3.48 | 15.13 | 33 | 64 | zymogen activation | APAF1, APOH, BAD, BAX, BOK, CASP9, COL4A3, CTSH, F2R, F3, FGA, HIP1, IFI16, KLKB1, SMAD3, P2RX1, SERPINE1, S100A8, S100A9, SNCA, CLEC3B, TRAF2, TRADD, RIPK1, CRADD, TNFSF10, TNFRSF10B, TNFRSF10A, EIF2AK3, TNFSF15, CASP8AP2, PDCD6, BCL2L11 |
431 | GO:0000183 | 0.00 | 3.47 | 7.33 | 16 | 31 | chromatin silencing at rDNA | PHF2, TBP, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HIST1H3F, TAF1B, TAF1A |
432 | GO:0050885 | 0.00 | 3.45 | 7.80 | 17 | 33 | neuromuscular process controlling balance | ABL1, ABL2, ALDH1A3, APLP2, APP, ATP2B2, BCR, CACNA1A, TPP1, GAA, GM2A, HEXB, RAC3, TNR, CLRN1, CNTNAP1, NRXN1 |
433 | GO:0032870 | 0.00 | 3.44 | 9.05 | 20 | 40 | cellular response to hormone stimulus | AVPR1B, AVPR2, BBS4, AKR1C4, CTSH, DUSP1, GATA4, GATA6, JUN, JUND, LIPC, OXTR, P2RY4, P2RY6, PRKCE, PTGDR, PTGER2, SLC34A1, TNFSF4, SLIT2 |
434 | GO:0007626 | 0.00 | 3.43 | 11.48 | 25 | 49 | locomotory behavior | ABAT, ADRA1B, ALDH1A3, APLP2, ASTN1, ATP2B2, CACNA1B, CHRNB2, CHRNB4, DBH, DRD3, ETV5, GAA, GRM1, HEXB, NRG1, HPRT1, HTR2C, IDO1, PEX13, SNAP25, STRN, TAL1, FZD4, RCAN2 |
435 | GO:0002703 | 0.00 | 3.43 | 9.66 | 21 | 41 | regulation of leukocyte mediated immunity | BTK, C3, CD28, CLC, FCER2, FGR, HPX, IFNG, IL10, IL13, PTAFR, RAC2, STAT6, STXBP2, TRAF2, TNFSF4, UNG, FZD5, VAMP8, IL27RA, GAB2 |
436 | GO:0031100 | 0.00 | 3.42 | 9.22 | 20 | 39 | organ regeneration | ANGPT2, ANXA3, APOH, CCNE1, CDK2, CDK4, CDKN1A, EIF4A1, F7, FGA, FLT3, HGF, HMBS, KLKB1, SRSF5, SHC1, TYMS, WNT1, SOCS3, RGN |
437 | GO:0072413 | 0.00 | 3.40 | 11.11 | 24 | 47 | signal transduction involved in mitotic cell cycle checkpoint | CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, UBB, CRADD, PSMF1, PSME3, PSMD14 |
438 | GO:1902402 | 0.00 | 3.40 | 11.11 | 24 | 47 | signal transduction involved in mitotic DNA damage checkpoint | CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, UBB, CRADD, PSMF1, PSME3, PSMD14 |
439 | GO:0031571 | 0.00 | 3.39 | 12.53 | 27 | 53 | mitotic G1 DNA damage checkpoint | CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, RPA2, TP73, UBB, TP63, CRADD, PSMF1, PSME3, PSMD14 |
440 | GO:0007568 | 0.00 | 3.37 | 25.17 | 54 | 107 | aging | ABAT, APAF1, APOH, ARG1, ASS1, ATP2B1, ATP5G3, BAX, TSPO, CANX, CASP9, CAT, CD86, CLU, CNP, CNR1, CREB1, CTGF, CTNNA1, DCN, DNMT1, EDNRA, F3, GHRHR, HMGCR, IGF1, IL10, IRAK1, JUN, JUND, KRT83, NTRK2, P2RY2, SERPINF1, PENK, PRKCQ, PTGS1, RPS6KB1, RXRA, CX3CL1, SHC1, SNCA, SOD2, SREBF1, STAT3, TACR3, TNFRSF1B, TYMS, PRDM2, MADCAM1, SOCS3, RGN, AURKB, LITAF |
441 | GO:0035150 | 0.00 | 3.36 | 18.20 | 39 | 77 | regulation of tube size | ADRA1B, AGTR1, AGTR2, ATP1A2, AVPR1B, AVPR2, BMPR2, CHRM1, CHRM3, CPS1, CRP, DBH, ACE, DRD5, EDNRA, F2R, FGA, GPX1, HMGCR, HRH1, ICAM1, INS, ITGA1, KCNJ8, KNG1, OXTR, P2RX1, P2RX4, P2RY2, PRKCQ, PTAFR, PTGS1, CX3CL1, SHC1, SOD2, VIP, ITGB1BP1, ATG5, KCNMB2 |
442 | GO:0032355 | 0.00 | 3.36 | 20.09 | 43 | 85 | response to estradiol | ANXA1, ASS1, BAD, BMP4, BRCA2, C3, CASP9, CAT, CCNE1, CD4, CDK2, COL1A1, CRHBP, CTGF, DNMT1, DNMT3B, DUSP1, ETS1, F3, FGA, HMBS, IGF1, IGF2, IHH, IL10, KCNJ11, OXTR, PAM, PENK, PTEN, PTN, RARA, SLC34A1, SRD5A1, STAT3, STAT5B, TACR3, NR2F2, PRDM2, NRIP1, MBD4, SOCS3, RAMP3 |
443 | GO:0010646 | 0.01 | 3.34 | 4.50 | 10 | 21 | regulation of cell communication | ACTL6A, ATP6V0A1, CSNK2A2, CTSK, CXADR, KAT2A, RYR2, ZBTB17, RUVBL1, RAB33A |
444 | GO:0046879 | 0.00 | 3.30 | 6.53 | 14 | 28 | hormone secretion | ACVR2B, AGTR1, AGTR2, IL1RN, PTPRN, PTPRN2, RAB1A, RAF1, STXBP3, HNF1A, VIP, FZD4, EIF2AK3, RIMS2 |
445 | GO:0010243 | 0.00 | 3.29 | 13.38 | 29 | 60 | response to organonitrogen compound | ADSS, AGTR2, ATP4B, TSPO, CCNE1, CDKN1A, DBH, DHFR, DUSP1, FLT3, HLCS, HPRT1, IRAK1, JUN, KCNC2, P2RX1, P2RX3, P2RX5, P2RX7, PTEN, PTGS1, PYGM, RANBP2, SELL, TP73, TRPC3, TYR, FOSL1, KYNU |
446 | GO:0030073 | 0.01 | 3.28 | 4.68 | 10 | 20 | insulin secretion | ACVR2B, ANXA1, IL1RN, PTPRN, PTPRN2, RAF1, STXBP3, HNF1A, EIF2AK3, RIMS2 |
447 | GO:0019318 | 0.04 | 3.28 | 2.81 | 6 | 12 | hexose metabolic process | FUT6, FUT8, GALE, GALK2, B4GALT1, MAN2B1 |
448 | GO:0060402 | 0.00 | 3.28 | 9.86 | 21 | 42 | calcium ion transport into cytosol | ATP1A2, CASQ1, CASQ2, CYBA, DIAPH1, PTK2B, XCR1, HRC, HTR2C, ITPR1, PLN, PRKCE, PRKD1, PTPN6, RYR1, RYR2, CCL21, SLC8A3, TRPM2, TRPV1, ATG5 |
449 | GO:0060541 | 0.02 | 3.28 | 3.75 | 8 | 16 | respiratory system development | ALDH1A3, ASS1, DLX5, EDA, RARA, KCNAB1, HESX1, PHOX2B |
450 | GO:0071241 | 0.00 | 3.27 | 18.43 | 39 | 78 | cellular response to inorganic substance | ALAD, ANXA5, ATF4, ATRX, BAD, TSPO, CCNB1, CD86, CDH1, CDK2, CREB1, CRHBP, CYP11B1, DNM2, DNMT1, DPEP1, GLRA1, GPLD1, GUCA1A, HMBS, JUN, JUND, KCNA1, KCNC2, KCNJ1, KCNK3, SERPINF1, PPP5C, RAD51, SCN5A, SLC34A1, SNCA, SYT1, TRAF2, TNFSF4, AKR1C3, EIF2AK3, EIF4A3, RASA4 |
451 | GO:0051928 | 0.02 | 3.27 | 3.75 | 8 | 16 | positive regulation of calcium ion transport | ATP2B2, TSPO, CAMK2A, CRH, GCG, FFAR1, STC1, WFS1 |
452 | GO:0010594 | 0.04 | 3.27 | 2.81 | 6 | 12 | regulation of endothelial cell migration | EFNA1, EPHA2, EMP2, FGF4, PRCP, PTK2 |
453 | GO:0008585 | 0.03 | 3.27 | 3.29 | 7 | 14 | female gonad development | BRCA2, COL9A3, IDH1, PGR, UBB, NRIP1, SLIT2 |
454 | GO:0060048 | 0.01 | 3.27 | 5.17 | 11 | 22 | cardiac muscle contraction | ATP1A3, GAA, KCNH2, SCN4B, SRSF1, TAZ, TNNC1, TNNI2, TNNI3, VEGFB, NUP155 |
455 | GO:0044259 | 0.00 | 3.27 | 15.13 | 32 | 64 | multicellular organismal macromolecule metabolic process | ADAM10, ARG1, BMP4, COL1A1, COL4A3, COL4A5, COL4A6, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, COL11A1, COL15A1, CTGF, CTSK, ACE, F2, F2R, FAP, IHH, ITGB1, CIITA, P2RX7, PEPD, ADAM17, AKR1C3, SERPINB7, ADAM15, ADAMTS3, ADAMTS2 |
456 | GO:0006595 | 0.00 | 3.26 | 14.65 | 31 | 62 | polyamine metabolic process | ARG1, ARG2, ASL, ASS1, CKM, CPS1, GATM, OAZ1, OAZ2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, SMS, PSMF1, SLC25A15, PSME3, PSMD14 |
457 | GO:0051437 | 0.00 | 3.26 | 13.71 | 29 | 58 | positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition | CCNB1, CDC20, CDC27, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, SKP1, UBB, CUL1, CDC23, CDC16, PSMF1, PSME3, PSMD14 |
458 | GO:0031016 | 0.03 | 3.26 | 3.29 | 7 | 14 | pancreas development | ACVR2B, HHEX, IGF1, IGF1R, IGF2, IHH, ISL1 |
459 | GO:1901215 | 0.01 | 3.26 | 4.24 | 9 | 18 | negative regulation of neuron death | ATF4, CREB1, IGF1, IL13, SERPINF1, PPP5C, STAT3, TRAF2, IKBKG |
460 | GO:0070555 | 0.02 | 3.26 | 3.76 | 8 | 16 | response to interleukin-1 | ANXA1, CYBA, ETS1, HNMT, PRKCI, SELE, SNCA, RIPK2 |
461 | GO:0008306 | 0.02 | 3.26 | 3.77 | 8 | 16 | associative learning | CRH, DRD5, GABRA5, SNAP25, SRF, TNR, RIN1, EIF4A3 |
462 | GO:0002479 | 0.00 | 3.26 | 11.34 | 24 | 48 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | CD36, CYBA, ITGAV, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, UBB, PSMF1, PSME3, PSMD14 |
463 | GO:0044275 | 0.01 | 3.26 | 4.71 | 10 | 20 | cellular carbohydrate catabolic process | CALM3, CPS1, G6PC, GAA, PHKA2, PHKB, PHKG1, PYGB, PYGM, MGAM |
464 | GO:0014013 | 0.00 | 3.25 | 10.40 | 22 | 44 | regulation of gliogenesis | ASCL2, BMP4, TSPO, CREB1, DRD3, EMX1, ETV5, F2, EFEMP1, FGFR3, GFAP, NTRK3, PRKCI, PTN, RHEB, SOX10, SOX11, CNTN2, TP73, RNF112, RNF10, OLIG2 |
465 | GO:1901888 | 0.00 | 3.25 | 7.55 | 16 | 32 | regulation of cell junction assembly | DAPK3, EFNA5, RAPGEF1, HRG, KDR, SMAD3, PTK2, PTPRJ, RAC1, SDC4, SLC9A1, SNAI1, TSC1, FZD5, RAPGEF2, SLK |
466 | GO:1904894 | 0.00 | 3.25 | 9.93 | 21 | 42 | positive regulation of STAT cascade | CSF1R, CTF1, F2R, PTK2B, FGFR3, FLT3, FYN, HCLS1, HPX, IFNA2, IFNG, IGF1, IL10, IL12B, IL13, IL18, ISL1, KIT, TNFRSF1A, TNFRSF18, TNFSF18 |
467 | GO:0055078 | 0.01 | 3.25 | 4.71 | 10 | 20 | sodium ion homeostasis | AGTR1, AVPR2, COMT, DRD3, KNG1, SCN7A, SCNN1A, SCNN1B, SCNN1G, UPK3A |
468 | GO:0007202 | 0.00 | 3.25 | 9.45 | 20 | 40 | activation of phospholipase C activity | ANG, ARHGAP6, AVPR1B, CALM3, CREB1, LPAR1, EDNRA, GNA15, GNAQ, ITPR1, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, SELE, S1PR4, GPR55 |
469 | GO:0031281 | 0.00 | 3.25 | 6.13 | 13 | 26 | positive regulation of cyclase activity | AVPR2, CALM3, DRD5, EDNRA, FSHR, GHRHR, GNAS, NTRK2, P2RY11, RAF1, VIP, VIPR2, WFS1 |
470 | GO:0098657 | 0.01 | 3.25 | 5.19 | 11 | 22 | import into cell | DRD3, GFAP, ITGA4, KCNJ10, NTSR1, RAB3B, SLC8A3, SLC22A3, SNAP25, SNCA, PICALM |
471 | GO:0050663 | 0.04 | 3.25 | 2.83 | 6 | 12 | cytokine secretion | ABCA1, CD36, RBPJ, RAB1A, S100A12, S100A13 |
472 | GO:0032092 | 0.00 | 3.25 | 7.08 | 15 | 30 | positive regulation of protein binding | ABL1, ABL2, ADD1, BMP4, KRIT1, EP300, EPB41, GCG, RAN, RFNG, VTN, NRP1, ARHGEF7, EIF2AK3, RAPGEF2 |
473 | GO:0002444 | 0.04 | 3.25 | 2.83 | 6 | 12 | myeloid leukocyte mediated immunity | ANXA3, BCR, ACE, STXBP3, ADAM17, STX11 |
474 | GO:0048678 | 0.04 | 3.25 | 2.83 | 6 | 12 | response to axon injury | ARG1, BAX, DPYSL3, FGFR3, KCNK2, RANGAP1 |
475 | GO:0051893 | 0.02 | 3.25 | 3.77 | 8 | 16 | regulation of focal adhesion assembly | ACVRL1, ARHGAP6, DAPK3, EFNA5, PTEN, PTK2, SLC9A1, SLK |
476 | GO:0002028 | 0.03 | 3.25 | 3.30 | 7 | 14 | regulation of sodium ion transport | ATP1A1, P2RX4, P2RX7, SCNN1B, SGK1, SLC9A3, SGK2 |
477 | GO:0003300 | 0.01 | 3.25 | 4.72 | 10 | 20 | cardiac muscle hypertrophy | AGTR2, CAV3, GATA4, GATA6, P2RX4, RYR2, AKAP1, SORBS2, CTDP1, KDM4A |
478 | GO:0043666 | 0.01 | 3.25 | 4.72 | 10 | 20 | regulation of phosphoprotein phosphatase activity | CRY2, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, SET, HSP90B1, TSC1, RGN, NUAK1 |
479 | GO:0032743 | 0.03 | 3.25 | 3.30 | 7 | 14 | positive regulation of interleukin-2 production | ABL1, ABL2, ANXA1, PDE4B, TRAF2, TNFSF4, RIPK2 |
480 | GO:0003044 | 0.00 | 3.25 | 7.09 | 15 | 30 | regulation of systemic arterial blood pressure mediated by a chemical signal | ADRA1B, AGTR1, AGTR2, AVPR1B, AVPR2, CYBA, ACE, DRD3, DRD5, F2R, OXTR, PCSK5, SLC2A5, SOD2, ATP6AP2 |
481 | GO:0043502 | 0.00 | 3.25 | 7.09 | 15 | 30 | regulation of muscle adaptation | CASQ1, CAV3, GTF2I, IGF1, P2RX4, RPS6KB1, SCN5A, SLC9A1, TNNC1, TRPC3, AKAP1, PDE5A, CTDP1, KLF4, AKAP6 |
482 | GO:0043550 | 0.00 | 3.25 | 6.62 | 14 | 28 | regulation of lipid kinase activity | EPHA8, PTK2B, FGFR3, FGR, FLT1, FLT3, KIT, PTK2, RAC1, RB1, RBL2, CCL21, PIK3R3, KLF4 |
483 | GO:0070076 | 0.04 | 3.25 | 2.83 | 6 | 12 | histone lysine demethylation | HSF4, PHF2, KDM6A, UTY, KDM5C, KDM4A |
484 | GO:0035249 | 0.04 | 3.25 | 2.83 | 6 | 12 | synaptic transmission, glutamatergic | CACNA1A, CACNB4, CDH8, CLCN3, GRID2, P2RX1 |
485 | GO:0034113 | 0.00 | 3.24 | 6.14 | 13 | 26 | heterotypic cell-cell adhesion | CD44, CD58, CXADR, FGA, IL1RN, ITGA4, ITGA5, ITGAD, ITGAV, ITGB1, NRCAM, MADCAM1, KLF4 |
486 | GO:0044786 | 0.00 | 3.24 | 6.14 | 13 | 26 | cell cycle DNA replication | ATRX, FEN1, PCNA, PRIM2, UPF1, RFC3, RFC4, RFC5, RPA2, RPA3, SMC1A, SMC3, GINS1 |
487 | GO:0051353 | 0.00 | 3.24 | 6.14 | 13 | 26 | positive regulation of oxidoreductase activity | ABL1, ABL2, AGTR1, AGTR2, CALM3, DHFR, PTK2B, FCER2, IFNG, INS, SNCA, FGF23, RGN |
488 | GO:0060395 | 0.00 | 3.24 | 6.14 | 13 | 26 | SMAD protein signal transduction | BMP1, BMP3, BMP4, BMP8B, GATA4, GDF9, INHA, JUN, SMAD1, SMAD3, SMAD9, VIM, GDF15 |
489 | GO:0033198 | 0.00 | 3.24 | 5.67 | 12 | 24 | response to ATP | KCNJ11, P2RX1, P2RX3, P2RX4, P2RX5, P2RX7, P2RY11, PTEN, SELL, HSP90B1, TRPC3, TRPV1 |
490 | GO:0043113 | 0.00 | 3.24 | 5.67 | 12 | 24 | receptor clustering | CACNA1A, DLG2, DLG3, ETV5, ITGA4, PTN, MADCAM1, SSNA1, ITGB1BP1, NRXN1, NRXN2, PICK1 |
491 | GO:0070231 | 0.00 | 3.24 | 5.67 | 12 | 24 | T cell apoptotic process | BAX, BMP4, CLC, DFFA, TSC22D3, IL2RA, IDO1, PRKCQ, RAG1, RIPK1, BCL2L11, PDCD7 |
492 | GO:0030431 | 0.01 | 3.24 | 5.20 | 11 | 22 | sleep | ALB, CHRNB2, CRH, DRD3, GHRHR, GRIN2A, IL18, OXTR, PTGDR, SRD5A1, PER3 |
493 | GO:0071868 | 0.01 | 3.24 | 5.20 | 11 | 22 | cellular response to monoamine stimulus | ABL1, APP, DNM2, DRD5, GNAS, KCNQ1, PDE4B, RYR2, SLC9A1, SNCA, SRD5A1 |
494 | GO:1903523 | 0.01 | 3.24 | 5.20 | 11 | 22 | negative regulation of blood circulation | AGTR2, ATP1A1, ATP1A2, BMPR2, CRP, F2R, HMGCR, INS, PLN, CX3CL1, PDE5A |
495 | GO:0045730 | 0.04 | 3.24 | 2.83 | 6 | 12 | respiratory burst | CD52, CYBA, PGAM1, PRKCQ, RAC1, RAC2 |
496 | GO:0000083 | 0.01 | 3.24 | 4.73 | 10 | 20 | regulation of transcription involved in G1/S transition of mitotic cell cycle | BACH1, CCNE1, DHFR, E2F6, ORC1, PCNA, RB1, RRM2, TYMS, KLF11 |
497 | GO:0001910 | 0.01 | 3.24 | 4.73 | 10 | 20 | regulation of leukocyte mediated cytotoxicity | ICAM1, IGF2, IL12B, P2RX7, SERPINB9, PVR, SERPINB4, XCL1, STAT5B, VAV1 |
498 | GO:0001975 | 0.01 | 3.24 | 4.73 | 10 | 20 | response to amphetamine | ADRA1B, CALM3, DBH, DRD3, DRD5, GRIN2A, HPRT1, ICAM1, OXTR, RANBP2 |
499 | GO:0022400 | 0.01 | 3.24 | 4.73 | 10 | 20 | regulation of rhodopsin mediated signaling pathway | CALM3, CNGA1, GNAT1, GNGT1, GUCA1A, GUCY2F, GUCY2D, PRKCQ, RCVRN, GUCA1C |
500 | GO:0019433 | 0.01 | 3.24 | 4.25 | 9 | 18 | triglyceride catabolic process | APOH, CPS1, FABP2, FABP7, GPLD1, LIPC, LIPE, PRKACB, PRKACG |
501 | GO:0021846 | 0.01 | 3.24 | 4.25 | 9 | 18 | cell proliferation in forebrain | EMX2, FABP7, HHEX, PCM1, RRM1, SIX3, TACC1, NUMB, ZEB2 |
502 | GO:0030513 | 0.01 | 3.24 | 4.25 | 9 | 18 | positive regulation of BMP signaling pathway | ACVRL1, BMP4, BMPR2, GATA4, GATA6, GPC3, RBPJ, ILK, SOX11 |
503 | GO:0033003 | 0.01 | 3.24 | 4.25 | 9 | 18 | regulation of mast cell activation | CNR1, FGR, IL13, IL13RA2, PTPRE, RAC2, STXBP2, VAMP8, GAB2 |
504 | GO:0044766 | 0.01 | 3.24 | 4.25 | 9 | 18 | multi-organism transport | BST2, EPS15, IFIT1, KPNA1, KPNA3, RAN, DYNLT1, TSG101, UBB |
505 | GO:0051932 | 0.01 | 3.24 | 4.25 | 9 | 18 | synaptic transmission, GABAergic | CLCN3, CNR1, DNM1, OXTR, PRKCE, PTEN, RAC1, RAC3, SYN3 |
506 | GO:0006465 | 0.02 | 3.24 | 3.78 | 8 | 16 | signal peptide processing | BGLAP, CLN5, F2, F7, F10, PCSK5, PROC, PROZ |
507 | GO:0021955 | 0.02 | 3.24 | 3.78 | 8 | 16 | central nervous system neuron axonogenesis | CHRNB2, DCC, EPHB1, EPHB3, PTEN, PTK2, PHOX2B, SLIT2 |
508 | GO:0050927 | 0.02 | 3.24 | 3.78 | 8 | 16 | positive regulation of positive chemotaxis | S1PR1, F3, F7, KDR, SMAD3, NTRK3, VEGFB, SCG2 |
509 | GO:0060292 | 0.02 | 3.24 | 3.78 | 8 | 16 | long term synaptic depression | ARF1, DRD5, PTK2B, GRIA1, PTEN, SRF, DGKI, PICK1 |
510 | GO:0060603 | 0.02 | 3.24 | 3.78 | 8 | 16 | mammary gland duct morphogenesis | CAV3, CSF1R, EPHA2, ETV4, ETV5, PGR, SLC12A2, SLIT2 |
511 | GO:0061418 | 0.02 | 3.24 | 3.78 | 8 | 16 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | ARNT, BACH1, EP300, RBPJ, UBB, UBE2D2, CUL2, RBX1 |
512 | GO:0075733 | 0.02 | 3.24 | 3.78 | 8 | 16 | intracellular transport of virus | BST2, IFIT1, KPNA1, KPNA3, RAN, DYNLT1, TSG101, UBB |
513 | GO:2000772 | 0.02 | 3.24 | 3.78 | 8 | 16 | regulation of cellular senescence | ABL1, ARNTL, BMPR1A, CDK6, HMGA1, ING2, TP63, NUAK1 |
514 | GO:0002089 | 0.03 | 3.24 | 3.31 | 7 | 14 | lens morphogenesis in camera-type eye | BMP4, CRYGB, EPHA2, FGFR3, SIX3, SOX11, BCAR3 |
515 | GO:0002715 | 0.03 | 3.24 | 3.31 | 7 | 14 | regulation of natural killer cell mediated immunity | IGF2, IL12B, SERPINB9, PVR, SERPINB4, STAT5B, VAV1 |
516 | GO:0007398 | 0.03 | 3.24 | 3.31 | 7 | 14 | ectoderm development | BMPR1A, EDA, FOXA2, ITGAM, KRT6B, ZBTB17, FZD7 |
517 | GO:0010656 | 0.03 | 3.24 | 3.31 | 7 | 14 | negative regulation of muscle cell apoptotic process | APOH, PTK2B, NRG1, HMGCR, IGF1, ILK, BAG3 |
518 | GO:0015874 | 0.03 | 3.24 | 3.31 | 7 | 14 | norepinephrine transport | AGTR2, CRH, FFAR3, OXTR, PTGS1, SLC22A1, SNCA |
519 | GO:0043304 | 0.03 | 3.24 | 3.31 | 7 | 14 | regulation of mast cell degranulation | FGR, IL13, IL13RA2, RAC2, STXBP2, VAMP8, GAB2 |
520 | GO:0043372 | 0.03 | 3.24 | 3.31 | 7 | 14 | positive regulation of CD4-positive, alpha-beta T cell differentiation | ANXA1, CD86, IFNG, IL12B, RARA, TNFSF4, RIPK2 |
521 | GO:0045191 | 0.03 | 3.24 | 3.31 | 7 | 14 | regulation of isotype switching | CD28, IFNG, IL10, STAT6, TNFSF4, UNG, IL27RA |
522 | GO:0045653 | 0.03 | 3.24 | 3.31 | 7 | 14 | negative regulation of megakaryocyte differentiation | HIST1H4I, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L |
523 | GO:0046641 | 0.03 | 3.24 | 3.31 | 7 | 14 | positive regulation of alpha-beta T cell proliferation | CD3E, CD28, IL12B, IL18, XCL1, TNFSF4, RIPK2 |
524 | GO:0060575 | 0.03 | 3.24 | 3.31 | 7 | 14 | intestinal epithelial cell differentiation | PRDM1, KLF5, CDKN1A, CDX2, GATA4, GATA6, TYMS |
525 | GO:0061383 | 0.03 | 3.24 | 3.31 | 7 | 14 | trabecula morphogenesis | CAV3, CHAD, COL1A1, S1PR1, NRG1, RBPJ, SRF |
526 | GO:0070897 | 0.03 | 3.24 | 3.31 | 7 | 14 | DNA-templated transcriptional preinitiation complex assembly | CREB1, PSMC1, PSMC2, PSMC3, PSMC4, TAF7, TAF1B |
527 | GO:0097066 | 0.03 | 3.24 | 3.31 | 7 | 14 | response to thyroid hormone | AK2, ANXA5, BMP4, KLF9, CTSH, KIT, SLC34A1 |
528 | GO:0001783 | 0.04 | 3.24 | 2.84 | 6 | 12 | B cell apoptotic process | BAX, BTK, IL10, PTEN, AURKB, BCL2L11 |
529 | GO:0003071 | 0.04 | 3.24 | 2.84 | 6 | 12 | renal system process involved in regulation of systemic arterial blood pressure | AGTR1, AGTR2, CYBA, EMP2, F2R, PCSK5 |
530 | GO:0007271 | 0.04 | 3.24 | 2.84 | 6 | 12 | synaptic transmission, cholinergic | CACNA1A, CHRM1, CHRM3, CHRNB2, CHRNB4, IFNG |
531 | GO:0008045 | 0.04 | 3.24 | 2.84 | 6 | 12 | motor neuron axon guidance | CHN1, EGR2, ETV4, SEMA3F, NRP1, SLIT2 |
532 | GO:0010453 | 0.04 | 3.24 | 2.84 | 6 | 12 | regulation of cell fate commitment | BMP4, BMPR1A, RBPJ, IL12B, FZD7, TNFSF18 |
533 | GO:0010971 | 0.04 | 3.24 | 2.84 | 6 | 12 | positive regulation of G2/M transition of mitotic cell cycle | APP, CDK4, RAD51C, RAD51B, SMARCD3, PHOX2B |
534 | GO:0014059 | 0.04 | 3.24 | 2.84 | 6 | 12 | regulation of dopamine secretion | ABAT, CHRNB2, CNR1, DRD3, PCP4, SNCA |
535 | GO:0032469 | 0.04 | 3.24 | 2.84 | 6 | 12 | endoplasmic reticulum calcium ion homeostasis | APP, ATP2A1, BAX, GRINA, ITPR1, WFS1 |
536 | GO:0032967 | 0.04 | 3.24 | 2.84 | 6 | 12 | positive regulation of collagen biosynthetic process | BMP4, CTGF, F2, F2R, IHH, SERPINB7 |
537 | GO:0035116 | 0.04 | 3.24 | 2.84 | 6 | 12 | embryonic hindlimb morphogenesis | ALX3, BMP4, FGF4, GPC3, GNAS, RARB |
538 | GO:0035589 | 0.04 | 3.24 | 2.84 | 6 | 12 | G-protein coupled purinergic nucleotide receptor signaling pathway | P2RY2, P2RY4, P2RY6, P2RY11, PTAFR, P2RY14 |
539 | GO:0035929 | 0.04 | 3.24 | 2.84 | 6 | 12 | steroid hormone secretion | AGTR1, AGTR2, CRH, GALR1, GDF9, FZD4 |
540 | GO:0042136 | 0.04 | 3.24 | 2.84 | 6 | 12 | neurotransmitter biosynthetic process | DAGLA, CHAT, COMT, GAD1, PAH, SLC22A2 |
541 | GO:0044253 | 0.04 | 3.24 | 2.84 | 6 | 12 | positive regulation of multicellular organismal metabolic process | BMP4, CTGF, F2, F2R, IHH, SERPINB7 |
542 | GO:0046636 | 0.04 | 3.24 | 2.84 | 6 | 12 | negative regulation of alpha-beta T cell activation | ANXA1, CBLB, IHH, XCL1, TNFSF4, TNFSF18 |
543 | GO:0052312 | 0.04 | 3.24 | 2.84 | 6 | 12 | modulation of transcription in other organism involved in symbiotic interaction | EP300, JUN, NTRK3, REST, SMARCA4, SP1 |
544 | GO:0061037 | 0.04 | 3.24 | 2.84 | 6 | 12 | negative regulation of cartilage development | BMP4, EFEMP1, RARA, RARB, SOX9, WNT11 |
545 | GO:0086064 | 0.04 | 3.24 | 2.84 | 6 | 12 | cell communication by electrical coupling involved in cardiac conduction | ATP1A1, ATP1A2, ATP1A3, CALM3, HRC, RYR2 |
546 | GO:1901017 | 0.04 | 3.24 | 2.84 | 6 | 12 | negative regulation of potassium ion transmembrane transporter activity | CASQ2, CAV3, KCNQ1, SUMO1, KCNAB1, OXSR1 |
547 | GO:1902259 | 0.04 | 3.24 | 2.84 | 6 | 12 | regulation of delayed rectifier potassium channel activity | KCNQ1, KCNS2, SUMO1, KCNAB1, AKAP7, AKAP6 |
548 | GO:0003018 | 0.00 | 3.20 | 20.56 | 43 | 87 | vascular process in circulatory system | ADRA1B, AGTR1, AGTR2, ANGPT1, ATP1A2, AVPR1B, AVPR2, BCR, BMPR2, CHRM1, CHRM3, CPS1, CRP, DBH, ACE, DRD5, EDNRA, F2R, FGA, GPX1, HMGCR, HRH1, ICAM1, INS, ITGA1, KCNJ8, KNG1, OXTR, P2RX1, P2RX4, P2RY2, PRKCQ, PTAFR, PTGS1, PTPRJ, CX3CL1, SHC1, SOD2, VIP, ITGB1BP1, SLIT2, ATG5, KCNMB2 |
549 | GO:0014070 | 0.00 | 3.20 | 20.25 | 43 | 90 | response to organic cyclic compound | ADSS, ANGPT2, ASCL1, ATP12A, BSG, CD36, COMT, DDX1, DHFR, EDNRA, KAT2A, HLCS, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, JUN, JUND, KCNC2, KCNJ8, P2RX1, P2RX3, P2RX5, PPP2R2A, PRKAA1, PRKACB, PRKAR2B, PRKCE, PRKCQ, PSMB2, ABCD3, PYGM, SELL, SELP, TRPC3, PEA15, RIPK2, KYNU, DDX21, EIF4A3 |
550 | GO:0042127 | 0.00 | 3.19 | 22.16 | 47 | 99 | regulation of cell proliferation | ABL2, AGTR1, ANGPT1, XIAP, FXYD2, BLK, BTK, CHEK1, CLC, CREB1, DBH, DHCR7, DNMT1, EMX1, FGR, NR5A2, FYN, CXCL3, GRPR, GUCY2C, HHEX, INHA, JUND, LMO1, SERPINE1, PF4V1, PTGER2, PTGS1, RPA3, SALL1, CXCL6, SGK1, SOS2, STAT6, TAL1, TNFRSF1A, TNFRSF1B, XRCC5, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, TNFSF18, ARHGEF2, NUAK1, SGK2, PRG4 |
551 | GO:1904062 | 0.00 | 3.18 | 15.30 | 32 | 65 | regulation of cation transmembrane transport | ABL1, BAX, BMP4, CACNB4, CASQ1, CYBA, DIAPH1, DPP6, EDNRA, F2, F2R, PTK2B, HRC, IL13, KCNC2, KCNJ1, KCNJ2, KCNJ11, KCNS2, PDE4B, PRKD1, PTPN6, RYR2, S100A1, XCL1, SNCA, TRPC1, RGN, AKAP7, AKAP6, ATG5, AKAP9 |
552 | GO:0038061 | 0.00 | 3.16 | 13.92 | 29 | 59 | NIK/NF-kappaB signaling | ALK, BIRC3, CHUK, PPP4C, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, RPS3, SKP1, UBB, CUL1, UBA3, PSMF1, PSME3, PSMD14 |
553 | GO:0060193 | 0.00 | 3.15 | 13.94 | 29 | 59 | positive regulation of lipase activity | ABL2, AGTR1, ANG, APOH, ARHGAP6, ARL1, AVPR1B, CALM3, CREB1, LPAR1, EDNRA, FGFR3, FLT1, GNA15, GNAQ, ITPR1, KIT, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PTAFR, SELE, NR1H2, S1PR4, GPR55 |
554 | GO:0048013 | 0.00 | 3.14 | 13.00 | 27 | 55 | ephrin receptor signaling pathway | ACTB, ADAM10, CHN1, AP2S1, DNM1, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EPHA2, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, FYN, RBPJ, LIMK1, NTRK3, PTK2, RAC1, ARHGEF7, ARPC5, ARPC1B, ACTR2, ARPC2 |
555 | GO:0048771 | 0.00 | 3.14 | 10.57 | 22 | 45 | tissue remodeling | ANXA1, ARG1, BGLAP, CAPN1, TPP1, CSF1R, CSPG4, CTSK, S1PR1, EPHA2, F2R, PTK2B, IAPP, IHH, IL1A, P2RX7, PDK4, RAC1, RAC2, SLC34A1, INPP4B, GPR55 |
556 | GO:0006521 | 0.00 | 3.14 | 12.53 | 26 | 53 | regulation of cellular amino acid metabolic process | BHMT, COMT, INS, OAZ1, OAZ2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PSMF1, NR1H4, PSME3, PSMD14 |
557 | GO:0071356 | 0.00 | 3.13 | 9.12 | 19 | 39 | cellular response to tumor necrosis factor | ASS1, ENTPD2, CD58, COL1A1, CRHBP, CYBA, KAT2A, ICAM1, KCNJ11, NTRK2, CCL21, CCL22, CCL25, XCL1, CX3CL1, XCL2, TRPV1, ARHGEF2, IL18BP |
558 | GO:0035637 | 0.00 | 3.13 | 27.65 | 57 | 117 | multicellular organismal signaling | ATP1A1, ATP1A2, ATP1A3, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, CACNA1A, CACNB4, CALM3, CASQ1, CASQ2, CHRNB4, CXADR, DPP6, DRD5, S1PR1, GLRA1, HRC, IFNG, ITPR1, KCNA1, KCND2, KCND3, KCNH2, KCNJ2, KCNJ11, KCNJ14, KCNK3, KCNQ1, NRCAM, P2RX1, P2RX3, P2RX4, FXYD3, PLN, RYR1, RYR2, SCN1A, SCN2A, SCN4B, SCN5A, SCN7A, SCN8A, SLC8A3, SLC9A1, TNNI3, TNR, TRPC1, CNTNAP1, KCNK6, NUP155, HCN4, ABCC9, AKAP9, KCNMB2 |
559 | GO:0072401 | 0.00 | 3.13 | 11.58 | 24 | 49 | signal transduction involved in DNA integrity checkpoint | CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, UBB, CRADD, PSMF1, PSME3, PSMD14 |
560 | GO:0002576 | 0.00 | 3.12 | 11.11 | 23 | 47 | platelet degranulation | ACTN1, ALB, APP, CALM3, CD9, CD36, CD63, CLU, FGA, HGF, HRG, IGF1, IGF2, KNG1, LAMP2, P2RX1, SERPINE1, PSAP, SELP, SPARC, TUBA4A, VEGFB, ABCC4 |
561 | GO:0007612 | 0.00 | 3.11 | 9.16 | 19 | 39 | learning | AMPH, BCHE, COMT, CTNND2, FYN, JUN, NTRK2, NTSR1, PRKAR2B, PTGS1, PTN, SLC8A3, CNTN2, FOSL1, AAAS, DGKI, NRXN3, NRXN1, NRXN2 |
562 | GO:0019438 | 0.00 | 3.10 | 8.00 | 17 | 37 | aromatic compound biosynthetic process | ALAD, ALAS2, ASIP, TSPO, COX15, CPOX, CTNS, DBH, HMBS, IDO1, PAH, QDPR, TRPC1, TYR, UROS, RAPGEF2, ABCB6 |
563 | GO:0016525 | 0.00 | 3.09 | 9.22 | 19 | 39 | negative regulation of angiogenesis | ANGPT2, APOH, KLK3, ADGRB2, KRIT1, COL4A3, CX3CR1, DCN, GTF2I, HHEX, HRG, FOXO4, SERPINE1, SERPINF1, PTN, SPARC, ITGB1BP1, KLF4, SEMA3E |
564 | GO:0022612 | 0.00 | 3.08 | 8.24 | 17 | 35 | gland morphogenesis | CD44, EDA, FGF7, HGF, IFNG, IGF1, IGF1R, SERPINB5, PTN, RPS6KA1, RXRA, SOX9, CUL3, TP63, NRP1, SLC9A3R1, FEM1B |
565 | GO:0070911 | 0.00 | 3.08 | 8.74 | 18 | 37 | global genome nucleotide-excision repair | ERCC3, ERCC4, PCNA, RAD23B, RFC3, RFC4, RFC5, RPA2, RPA3, SUMO3, UBB, SUMO1, XPA, CUL4A, COPS3, COPS2, CHD1L, RBX1 |
566 | GO:0022617 | 0.00 | 3.08 | 16.07 | 33 | 68 | extracellular matrix disassembly | ADAM10, BMP1, BSG, CAPN1, CD44, CDH1, COL1A1, COL4A3, COL4A5, COL4A6, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, COL11A1, COL15A1, CTRB1, CTSK, DCN, DPP4, ELN, ETS1, FAP, FBN1, KLKB1, LAMA3, FSCN1, ADAM17, TPSAB1, ADAM15, ADAMTS4 |
567 | GO:0002790 | 0.00 | 3.07 | 6.78 | 14 | 29 | peptide secretion | ABCA1, ACVR2B, ANXA1, IL1RN, PTPRN, PTPRN2, RAB1A, RAF1, STXBP3, HNF1A, VIP, TRPV1, EIF2AK3, RIMS2 |
568 | GO:0048015 | 0.00 | 3.07 | 27.41 | 56 | 116 | phosphatidylinositol-mediated signaling | ANGPT1, BAD, CASP9, CAT, CBL, CD28, CD86, CDKN1A, CHUK, CREB1, CRYBA1, CSF1R, DCN, F2, F2R, FGF3, FGF4, FGF7, FGFR3, FGR, FLT1, FLT3, FSHR, FYN, GRB2, HCLS1, HGF, NRG1, NR4A1, IGF1, IGF1R, INS, KDR, KIT, KITLG, FOXO4, NTRK2, PIK3C2B, PI4KA, PTAFR, PTEN, PTK2, PTPN6, RPS6KB1, RPS6KB2, SELP, SOX9, TYRO3, UBE3A, VAV1, FGF23, OGT, KLF4, SLC9A3R1, NRG2, GAB2 |
569 | GO:0006283 | 0.00 | 3.07 | 8.27 | 17 | 35 | transcription-coupled nucleotide-excision repair | EP300, ERCC3, ERCC4, ERCC6, HMGN1, PCNA, RFC3, RFC4, RFC5, RPA2, RPA3, UBB, XPA, CUL4A, COPS3, COPS2, RBX1 |
570 | GO:0045761 | 0.00 | 3.07 | 8.27 | 17 | 35 | regulation of adenylate cyclase activity | AVPR2, CALM3, DRD3, DRD5, EDNRA, FSHR, GALR1, GHRHR, GNAS, NTRK2, P2RY11, PALM, RAF1, VIP, VIPR2, WFS1, GABBR2 |
571 | GO:0046620 | 0.00 | 3.07 | 8.27 | 17 | 35 | regulation of organ growth | ACACB, CAV3, CCNB1, CXADR, GATA4, GATA6, NRG1, RBPJ, KCNK2, PTEN, PTK2, RAG2, TP73, LATS1, CTDP1, AKAP6, BCL2L11 |
572 | GO:0044774 | 0.00 | 3.07 | 15.13 | 31 | 64 | mitotic DNA integrity checkpoint | CDK2, CDKN1A, FOXO4, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, RPA2, SETMAR, TOP2A, TOP2B, TP73, UBB, TP63, CRADD, PSMF1, PSME3, PSMD14 |
573 | GO:2001056 | 0.00 | 3.07 | 15.13 | 31 | 64 | positive regulation of cysteine-type endopeptidase activity | APAF1, BAD, BAX, BOK, CASP9, COL4A3, CTGF, CTSH, F2R, F3, HIP1, IFI16, SMAD3, P2RX1, REST, RPS3, S100A8, S100A9, SNCA, TRAF2, TRADD, RIPK1, CRADD, TNFSF10, TNFRSF10B, TNFRSF10A, EIF2AK3, TNFSF15, CASP8AP2, PDCD6, BCL2L11 |
574 | GO:0017038 | 0.00 | 3.06 | 6.31 | 13 | 27 | protein import | CLU, HSPA4, LAMP2, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX19, PEX5, PEX16, TOMM20 |
575 | GO:0002755 | 0.00 | 3.06 | 7.80 | 16 | 33 | MyD88-dependent toll-like receptor signaling pathway | BTK, CD36, CHUK, CREB1, ELK1, IRAK1, IRAK2, IRF1, JUN, PPP2R5D, RPS6KA1, SKP1, UBB, CUL1, IKBKG, RIPK2 |
576 | GO:0071300 | 0.00 | 3.06 | 7.80 | 16 | 33 | cellular response to retinoic acid | ABCA1, ABL2, COL1A1, BRINP1, PTK2B, KRT13, NTRK3, SERPINF1, RARA, SOX9, WNT11, ZNF35, FZD4, FZD7, OGT, KLF4 |
577 | GO:0010332 | 0.00 | 3.04 | 7.33 | 15 | 31 | response to gamma radiation | ATR, BAX, BCL2L1, BRCA2, CYBA, ELK1, ERCC6, GPX1, PRKAA1, RAD51, TP73, XRCC2, XRCC5, TP63, SOCS3 |
578 | GO:0038123 | 0.00 | 3.04 | 7.33 | 15 | 31 | toll-like receptor TLR1:TLR2 signaling pathway | BTK, CD36, CHUK, CREB1, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, RPS6KA1, SKP1, UBB, CUL1, IKBKG, RIPK2 |
579 | GO:0038124 | 0.00 | 3.04 | 7.33 | 15 | 31 | toll-like receptor TLR6:TLR2 signaling pathway | BTK, CD36, CHUK, CREB1, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, RPS6KA1, SKP1, UBB, CUL1, IKBKG, RIPK2 |
580 | GO:0009617 | 0.00 | 3.03 | 37.96 | 77 | 162 | response to bacterium | ABCA1, ABL1, ADH5, ALAD, ARG1, ASS1, ATP4B, AXL, BCR, PRDM1, BYSL, TSPO, CASP9, CD6, CD86, TNFRSF8, ENTPD2, CHUK, CNP, CNR1, COMT, CPS1, CX3CR1, DCN, DNMT1, EDNRA, F2R, F3, GPX1, CXCL3, HMGCS2, ICAM1, IGF1, IL10RA, IL12RB2, IL13, IL18, IDO1, IRAK1, IRAK2, IRF5, JUN, JUND, KCNJ8, P2RY2, PDE4B, PENK, PF4V1, SERPINB9, PRKCE, PTAFR, PTGER1, PTGER2, RARA, UPF1, RPS6KB1, CXCL5, SELE, SNCA, SPARC, STAT5B, TNFRSF1B, TNFSF4, SCGB1A1, VIL1, FZD5, OGT, PPM1D, PARG, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, SOCS3, LITAF, NR1H4, IL18BP |
581 | GO:0022037 | 0.00 | 3.03 | 12.76 | 26 | 54 | metencephalon development | ABAT, ABL1, ABL2, AGTR2, ARCN1, PHOX2A, ASCL1, RERE, ATP2B2, CACNA1A, LPAR1, KAT2A, GRID2, OGDH, OTX1, OTX2, PTN, PTPRS, SCN5A, NR2C2, WNT1, USP9X, FZD4, ATRN, NRXN1, SLC4A7 |
582 | GO:0055117 | 0.00 | 3.02 | 6.36 | 13 | 27 | regulation of cardiac muscle contraction | ADRA1B, CALM3, CASQ2, CAV3, CTGF, HRC, KCNQ1, SMAD7, P2RX4, SLC9A1, PDE5A, GSTO1, HCN4 |
583 | GO:0006482 | 0.00 | 3.01 | 6.38 | 13 | 27 | protein demethylation | HSF4, PHF2, KDM6A, UTY, KDM5C, HIST1H4I, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, KDM4A |
584 | GO:0030029 | 0.01 | 3.01 | 4.88 | 10 | 21 | actin filament-based process | KCNH2, KCNQ1, SCN4B, SELE, TNNC2, TNNI2, TNNI3, TPM2, VIM, NUP155 |
585 | GO:0043401 | 0.00 | 3.00 | 21.27 | 43 | 90 | steroid hormone mediated signaling pathway | NR0B1, ARNTL, BMP4, CCNE1, CRY2, DDX5, EP300, ESRRG, NR5A2, GHRHR, NR4A1, HNF4G, IGF1, ISL1, SCGB2A1, CNOT2, PGR, PPP5C, RAN, RARA, RARB, RB1, RNF6, RXRA, RXRG, SGK1, SMARCA4, TAF7, NR2F1, NR2F2, NR2C1, NR2C2, UBE3A, NR1H2, NRIP1, BUD31, CLOCK, RNF14, NR1I3, NR1H4, NR1D2, NR2E3, HDAC6 |
586 | GO:1901654 | 0.00 | 3.00 | 9.83 | 20 | 42 | response to ketone | AGTR2, ARG1, ASS1, KLF9, CASP9, CPS1, DNMT3B, F7, GNAI1, GNAS, HMBS, P2RY4, P2RY6, SERPINF1, PRKAA1, PRKCE, PTAFR, CCL21, TNFSF4, SLIT2 |
587 | GO:0048260 | 0.01 | 2.99 | 5.91 | 12 | 25 | positive regulation of receptor-mediated endocytosis | ANGPT1, BICD1, CAV3, CBL, CD63, HIP1, SERPINE1, CCL21, SELE, VTN, SYNJ1, PICK1 |
588 | GO:0030901 | 0.01 | 2.98 | 5.42 | 11 | 23 | midbrain development | APLP2, PHOX2A, EN1, KAT2A, SMAD1, SMAD9, OTX1, OTX2, RYK, WNT1, FZD6 |
589 | GO:0030900 | 0.00 | 2.98 | 17.28 | 35 | 74 | forebrain development | NR0B1, APAF1, APLP2, APP, ATRX, BMPR1A, CDH1, CHRNB2, CNP, CREB1, CRH, ETS1, FGFR3, FYN, GHRHR, GNAQ, RBPJ, ISL1, KCNC2, OTX1, OTX2, PCDH9, PTN, RAC3, STIL, SOX3, NR2F2, TOP2B, UBB, WNT1, OGT, CHRD, HESX1, RAPGEF2, OLIG2 |
590 | GO:0030534 | 0.01 | 2.97 | 4.93 | 10 | 21 | adult behavior | BBS4, CHRNB2, CHRNB4, CRHBP, DBH, GHSR, PTEN, NRXN3, NRXN1, NRXN2 |
591 | GO:0002448 | 0.01 | 2.97 | 5.44 | 11 | 23 | mast cell mediated immunity | FGR, IL13, IL13RA2, KIT, SERPINB9, RAC2, S100A13, STXBP2, LAT2, VAMP8, GAB2 |
592 | GO:0007157 | 0.01 | 2.97 | 5.44 | 11 | 23 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | CD6, CXADR, GRID2, ICAM1, ITGA4, ITGA5, CD200, PVR, SELE, SELP, NRXN1 |
593 | GO:0031103 | 0.01 | 2.97 | 5.44 | 11 | 23 | axon regeneration | TSPO, CTNNA1, DHFR, ISL1, JUN, NTRK3, PTEN, RXRA, TNR, KLF4, CHST3 |
594 | GO:0032922 | 0.01 | 2.97 | 5.44 | 11 | 23 | circadian regulation of gene expression | ARNTL, ATF4, CRY2, CSNK1D, DRD3, TOP1, NRIP1, OGT, PER3, USP2, CLOCK |
595 | GO:0051897 | 0.00 | 2.97 | 10.40 | 21 | 44 | positive regulation of protein kinase B signaling | ANGPT1, AXL, CD28, F3, F7, F10, GPX1, HCLS1, NRG1, IGF1, IGF1R, IGF2, ILK, INS, PTK2, PTPRJ, CCL21, VEGFB, AKR1C3, ITGB1BP1, BAG4 |
596 | GO:0006874 | 0.00 | 2.97 | 41.53 | 83 | 176 | cellular calcium ion homeostasis | ABL1, ABL2, ADRA1B, AGTR1, ANXA6, ATP1A2, ATP2B1, ATP2B2, ATP2B3, AVPR1B, BMP4, CACNA1A, CACNB4, CALM3, CASQ1, CASQ2, CAV3, CD4, CD36, CD52, CCR3, CCR8, CYBA, DIAPH1, DRD3, DRD5, S1PR1, LPAR1, EDNRA, F2, F2R, PTK2B, GALR1, GNA15, GNAT2, GNG3, XCR1, GRM1, GTF2I, HEXB, HRC, HTR2C, IL13, ITGB1, KCNK3, KISS1, KNG1, NTSR1, OXTR, P2RX3, P2RX4, P2RX5, P2RX7, P2RY2, P2RY4, PLN, PRKCE, PRKD1, PTPN6, PYGM, RYR1, RYR2, CCL21, XCL1, SLC8A3, SNCA, STC1, TNNI3, TPT1, HSP90B1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, TRPV1, S1PR4, INPP4B, RGN, VAPB, GSTO1, AKAP6, ATG5 |
597 | GO:0008625 | 0.01 | 2.96 | 4.94 | 10 | 21 | extrinsic apoptotic signaling pathway via death domain receptors | BAD, BAX, SORT1, TNFRSF1A, CRADD, TNFRSF18, TNFRSF10D, BAG3, KIAA0141, CASP8AP2 |
598 | GO:0071383 | 0.00 | 2.96 | 12.87 | 26 | 55 | cellular response to steroid hormone stimulus | AGTR2, ANXA1, ARG1, ASS1, ATP1A1, ATP1A2, ATP1A3, ATP2B1, KLF9, CASP9, CRH, CRHBP, DNMT3B, ELK1, FLT3, HMBS, HMGCS2, IL10, SERPINF1, SERPINB9, REST, SRD5A1, STC1, UBE2L3, AKR1C3, RAMP3 |
599 | GO:0010810 | 0.02 | 2.96 | 4.44 | 9 | 19 | regulation of cell-substrate adhesion | DAPK3, EFNA5, ONECUT1, ATXN3, PTK2, RAC2, SLC9A1, ONECUT2, SLK |
600 | GO:1901343 | 0.00 | 2.96 | 9.93 | 20 | 42 | negative regulation of vasculature development | ANGPT2, APOH, KLK3, ADGRB2, BMP4, KRIT1, COL4A3, CX3CR1, DCN, GTF2I, HHEX, HRG, FOXO4, SERPINE1, SERPINF1, PTN, SPARC, ITGB1BP1, KLF4, SEMA3E |
601 | GO:0002690 | 0.01 | 2.96 | 4.95 | 10 | 21 | positive regulation of leukocyte chemotaxis | F7, PTK2B, SERPINE1, PF4V1, CXCL6, CXCL5, CX3CL1, VEGFB, TNFSF18, CXCL14 |
602 | GO:0002279 | 0.01 | 2.95 | 4.96 | 10 | 21 | mast cell activation involved in immune response | FGR, IL13, IL13RA2, KIT, RAC2, S100A13, STXBP2, LAT2, VAMP8, GAB2 |
603 | GO:0042769 | 0.01 | 2.95 | 4.96 | 10 | 21 | DNA damage response, detection of DNA damage | PCNA, RFC3, RFC4, RFC5, RPA2, RPA3, RPS3, UBB, CUL4A, RBX1 |
604 | GO:0043471 | 0.01 | 2.95 | 4.96 | 10 | 21 | regulation of cellular carbohydrate catabolic process | ADRA1B, ARNT, IGF1, INS, P2RX7, PGAM1, PRKAA1, PRKAG1, STAT3, OGT |
605 | GO:0060324 | 0.01 | 2.95 | 4.96 | 10 | 21 | face development | ALDH1A3, BBS4, COL1A1, DLX5, ITGA4, PAX9, RAF1, RARA, SOX3, SRF |
606 | GO:0060338 | 0.01 | 2.95 | 4.96 | 10 | 21 | regulation of type I interferon-mediated signaling pathway | ADAR, UBE2K, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, PTPN6, STAT2, SOCS3 |
607 | GO:0060326 | 0.00 | 2.95 | 25.47 | 51 | 108 | cell chemotaxis | ADAM10, AGTR1, ANXA1, CX3CR1, CXADR, LPAR1, EDNRA, EPHA2, EPHB1, F7, PTK2B, FLT1, CXCL3, HGF, HRH1, IFNG, IL10, ITGA1, ITGA9, KIT, SERPINE1, PDE4B, PF4V1, PRKCQ, RAC1, RAC2, RPS19, S100A7, S100A8, S100A9, S100A12, SAA4, CCL21, CCL22, CCL25, CXCL6, CXCL5, XCL1, CX3CL1, SFTPD, XCL2, ADAM17, VAV1, VEGFB, SCG2, ARHGEF5, TNFSF14, TNFSF18, SLIT2, CXCL14, BCAR1 |
608 | GO:0048010 | 0.00 | 2.94 | 36.09 | 72 | 153 | vascular endothelial growth factor receptor signaling pathway | ACTB, ANGPT1, ARAF, AXL, BMPR2, CALM3, CAMK2A, CSF2RB, CTNNA1, CYBA, DUSP5, PTK2B, FGF3, FGF4, FGF7, FGFR3, FLT4, FYN, GRB2, GRIN2A, NRG1, HSPB1, IL2RA, ITGAV, ITPR1, KDR, KIT, MARK3, KITLG, PPP5C, PRKD1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTK2, PTPRA, RAC1, RAF1, RASA2, SHB, SHC1, UBB, VAV1, FGF23, CUL3, PEA15, NRP2, NRP1, PSMF1, NRG2, BCAR1, RAPGEF2, RBX1, AKAP9, RASA4, WASF2, PSME3, PSMD14 |
609 | GO:0007272 | 0.00 | 2.94 | 13.94 | 28 | 59 | ensheathment of neurons | CD9, CLU, LPAR1, EGR2, FGFR3, HEXB, HGF, NRG1, IFNG, ILK, KCNJ10, MAL, PTEN, RARA, RARB, RXRA, SCN2A, SCN8A, SLC8A3, CNTN2, TSC1, ZNF24, ATRN, CNTNAP1, EIF2B2, EIF2AK3, RNF10, OLIG2 |
610 | GO:0043534 | 0.02 | 2.93 | 4.47 | 9 | 19 | blood vessel endothelial cell migration | ANGPT1, EFNA1, EPHA2, EMP2, PTK2B, GPX1, HSPB1, PRCP, PRKD1 |
611 | GO:0070371 | 0.03 | 2.92 | 3.97 | 8 | 17 | ERK1 and ERK2 cascade | CTSH, EPHA2, EPHB1, ITGAV, OXTR, PTPN6, SOX9, STYX |
612 | GO:0000578 | 0.02 | 2.92 | 4.49 | 9 | 19 | embryonic axis specification | FOXA2, HOXD8, SMAD6, OTX2, STIL, KDM6A, WNT1, FZD5, FRAT1 |
613 | GO:0002704 | 0.02 | 2.92 | 4.49 | 9 | 19 | negative regulation of leukocyte mediated immunity | BCR, BST2, IFNA2, IGF2, IL13RA2, SERPINB9, PTPN6, SERPINB4, XCL1 |
614 | GO:0006607 | 0.02 | 2.92 | 4.49 | 9 | 19 | NLS-bearing protein import into nucleus | RERE, CBLB, FYB, KPNA1, KPNA2, KPNA3, KPNA4, IPO5, RANBP2 |
615 | GO:0014743 | 0.02 | 2.92 | 4.49 | 9 | 19 | regulation of muscle hypertrophy | CAV3, IGF1, P2RX4, SLC9A1, TRPC3, AKAP1, PDE5A, CTDP1, AKAP6 |
616 | GO:0045824 | 0.02 | 2.92 | 4.49 | 9 | 19 | negative regulation of innate immune response | ADAR, IFI16, IGF2, INS, SERPINB9, RPS19, SERPINB4, TYRO3, NR1H2 |
617 | GO:0048873 | 0.02 | 2.92 | 4.49 | 9 | 19 | homeostasis of number of cells within a tissue | ADD1, BAX, CD7, F2R, FLT3, P2RX7, RAC1, RAC3, SOX9 |
618 | GO:1903959 | 0.02 | 2.92 | 4.49 | 9 | 19 | regulation of anion transmembrane transport | CLCN3, CLCN6, CLCN7, CLCNKA, CLCNKB, PTAFR, SLC34A1, VDAC2, RIPK1 |
619 | GO:0043281 | 0.00 | 2.91 | 11.99 | 24 | 51 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | APAF1, BAD, BOK, CASP9, COL4A3, CTGF, CTSH, F2R, F3, HIP1, MGMT, P2RX1, REST, RPS3, S100A8, S100A9, TP63, CRADD, EIF2AK3, KIAA0141, TNFSF15, CASP8AP2, PDCD6, BCL2L11 |
620 | GO:1903522 | 0.00 | 2.91 | 36.30 | 72 | 154 | regulation of blood circulation | ADRA1B, AGTR1, ATP1A3, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, AVPR1B, AVPR2, CACNA1B, CACNB4, CALM3, CASQ1, CASQ2, CAV3, CHRM1, CHRM3, CPS1, CTGF, CXADR, DBH, ACE, FGA, GAA, GATA4, HRH1, HRC, ICAM1, IFNG, ITPR1, KCND2, KCND3, KCNH2, KCNJ2, KCNJ11, KCNJ14, KCNK3, KCNQ1, SMAD7, OXTR, P2RX1, P2RX4, P2RY2, PDE4B, FXYD3, PRKCQ, PTAFR, PTGS1, RYR1, RYR2, S100A1, SCN4B, SCN5A, SHC1, SLC8A3, SLC9A1, SREBF1, STC1, TACR3, TNNI3, TRPC1, SUMO1, VIP, KCNK6, GSTO1, NUP155, HCN4, ABCC9, AKAP9, KCNMB2, IRX5 |
621 | GO:0010595 | 0.00 | 2.91 | 8.51 | 17 | 36 | positive regulation of endothelial cell migration | ANGPT1, ANXA3, BMP4, BMPR2, ETS1, PTK2B, FLT4, GPLD1, HSPB1, KDR, PRKD1, SPARC, NRP2, NRP1, ITGB1BP1, BCAR1, PDCD6 |
622 | GO:0031145 | 0.00 | 2.90 | 16.07 | 32 | 68 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | BUB1B, CCNB1, CDC20, CDC27, CDK2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, SKP1, UBB, CUL1, CDC23, CDC16, AURKB, PSMF1, PSME3, PSMD14 |
623 | GO:0022408 | 0.03 | 2.90 | 4.00 | 8 | 17 | negative regulation of cell-cell adhesion | ABL1, ABL2, CDH1, IL1RN, PTK2, TNR, WNT1, KLF4 |
624 | GO:0046148 | 0.03 | 2.89 | 4.01 | 8 | 17 | pigment biosynthetic process | ALAD, ALAS2, TSPO, COX15, CPOX, HMBS, UROS, AP3D1 |
625 | GO:0060337 | 0.03 | 2.89 | 4.01 | 8 | 17 | type I interferon signaling pathway | BST2, IFIT1, IFIT3, IRF1, IRF5, ISG20, OAS3, SP100 |
626 | GO:0046635 | 0.03 | 2.89 | 4.01 | 8 | 17 | positive regulation of alpha-beta T cell activation | ANXA1, CD86, IFNG, IHH, PRKCQ, RARA, AP3B1, AP3D1 |
627 | GO:0006308 | 0.03 | 2.88 | 4.01 | 8 | 17 | DNA catabolic process | DNASE1, DNASE1L1, DNASE1L2, DNASE1L3, ISG20, KPNA1, SETMAR, TATDN2 |
628 | GO:0014911 | 0.03 | 2.88 | 4.02 | 8 | 17 | positive regulation of smooth muscle cell migration | LPAR1, F3, IGF1, P2RY2, P2RY6, RPS6KB1, VTN, NRP1 |
629 | GO:0030947 | 0.03 | 2.88 | 4.02 | 8 | 17 | regulation of vascular endothelial growth factor receptor signaling pathway | ARNT, FLT1, HHEX, ITGA5, VEGFB, VTN, FZD4, PDCD6 |
630 | GO:0042745 | 0.03 | 2.88 | 4.02 | 8 | 17 | circadian sleep/wake cycle | AHCY, ALB, CHRNB2, CRH, DRD3, GHRHR, SRD5A1, PER3 |
631 | GO:0044062 | 0.03 | 2.88 | 4.02 | 8 | 17 | regulation of excretion | AGTR1, AGTR2, AVPR2, COMT, DRD3, KNG1, STC1, SLC9A3R1 |
632 | GO:0071378 | 0.03 | 2.88 | 4.02 | 8 | 17 | cellular response to growth hormone stimulus | CSH1, GH2, PTK2, PTPN6, STAT3, STAT5B, ADAM17, SOCS3 |
633 | GO:0051352 | 0.00 | 2.88 | 18.67 | 37 | 79 | negative regulation of ligase activity | ABL1, BUB1B, CCNB1, CDC20, CDC27, CENPF, DUSP1, LIMK1, SMAD7, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, TTK, UBB, ZNF207, CDC23, CDC16, RGN, ZW10, PSMF1, BAG5, PSME3, PSMD14 |
634 | GO:1903035 | 0.00 | 2.88 | 7.53 | 15 | 32 | negative regulation of response to wounding | ABAT, ANXA5, APOH, F2, FAP, FGA, GP1BA, HMGCR, HRG, KLKB1, KNG1, SERPINE1, TNR, USF1, VTN |
635 | GO:0044706 | 0.04 | 2.87 | 3.51 | 7 | 15 | multi-multicellular organism process | ARNTL, EDNRA, B4GALT1, SMCP, P2RX1, PTAFR, DDO |
636 | GO:1904063 | 0.00 | 2.86 | 7.56 | 15 | 32 | negative regulation of cation transmembrane transport | ATP1A2, CALM3, CASQ2, CAV3, DRD3, KCNH2, KCNQ1, NTSR1, PLN, PRKCE, SUMO1, KCNAB1, SLC9A3R1, GSTO1, OXSR1 |
637 | GO:1900046 | 0.00 | 2.86 | 11.11 | 22 | 47 | regulation of hemostasis | ABAT, ANXA5, APOH, CD36, F2, F2R, F3, F7, FAP, FGA, GP1BA, FOXA2, HRG, KLKB1, KNG1, SERPINE1, PRKCQ, PROC, S100A9, SELP, USF1, VTN |
638 | GO:0050848 | 0.00 | 2.85 | 10.63 | 21 | 45 | regulation of calcium-mediated signaling | CALM3, CASQ2, CD3E, CD4, CD8A, RCAN1, PTK2B, NRG1, HRC, IGF1, ITPR1, P2RX3, P2RX4, P2RX5, PLN, SLC9A1, SLC12A1, RGN, GSTO1, AKAP6, RCAN2 |
639 | GO:0003009 | 0.04 | 2.84 | 3.54 | 7 | 15 | skeletal muscle contraction | CHUK, GAA, RPS6KB1, TNNC2, TNNC1, TNNI2, TNNI3 |
640 | GO:0098900 | 0.04 | 2.84 | 3.54 | 7 | 15 | regulation of action potential | CXADR, IFNG, KCNJ2, NTSR1, RYR2, SCN5A, SLC9A1 |
641 | GO:0008015 | 0.00 | 2.84 | 8.04 | 16 | 35 | blood circulation | ANGPT1, BCR, COL4A3, CYB5R3, RCAN1, ELN, EPB41, ITGA1, KCNJ8, KNG1, MEOX2, OLR1, PTPRJ, XCL2, ITGB1BP1, SLIT2 |
642 | GO:0003016 | 0.04 | 2.83 | 3.54 | 7 | 15 | respiratory system process | ADH5, ATP1A2, GAA, GLRA1, TNNC1, KDM6A, PHOX2B |
643 | GO:0003197 | 0.04 | 2.83 | 3.54 | 7 | 15 | endocardial cushion development | BMP4, BMPR1A, ERG, GATA4, RBPJ, ISL1, SOX9 |
644 | GO:0016338 | 0.04 | 2.83 | 3.54 | 7 | 15 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules | CLDN3, CX3CL1, CLDN12, CLDN10, CLDN8, CLDN6, CLDN1 |
645 | GO:0032528 | 0.04 | 2.83 | 3.54 | 7 | 15 | microvillus organization | KLF5, RAP1GAP, RAP2A, FSCN1, VIL1, SLC9A3R1, RAPGEF2 |
646 | GO:0042119 | 0.04 | 2.83 | 3.54 | 7 | 15 | neutrophil activation | ANXA3, BCR, PTAFR, STXBP2, STXBP3, TYROBP, STX11 |
647 | GO:0045577 | 0.04 | 2.83 | 3.54 | 7 | 15 | regulation of B cell differentiation | BAD, PRDM1, BTK, FLT3, INHA, PTPN6, STAT5B |
648 | GO:0045622 | 0.04 | 2.83 | 3.54 | 7 | 15 | regulation of T-helper cell differentiation | ANXA1, CD86, IL12B, RARA, TNFSF4, RIPK2, TNFSF18 |
649 | GO:0060669 | 0.04 | 2.83 | 3.54 | 7 | 15 | embryonic placenta morphogenesis | GRB2, IL10, ITGA4, LLGL2, ST14, FZD5, SOCS3 |
650 | GO:0071624 | 0.04 | 2.83 | 3.54 | 7 | 15 | positive regulation of granulocyte chemotaxis | EDNRA, CXCL3, RAC1, RAC2, S100A7, CCL21, XCL1 |
651 | GO:0072132 | 0.04 | 2.83 | 3.54 | 7 | 15 | mesenchyme morphogenesis | ACTG2, BMPR1A, RBPJ, ISL1, SMAD3, SOX9, WNT11 |
652 | GO:0090022 | 0.04 | 2.83 | 3.54 | 7 | 15 | regulation of neutrophil chemotaxis | EDNRA, CXCL3, RAC1, RAC2, CCL21, XCL1, SLIT2 |
653 | GO:0038095 | 0.00 | 2.83 | 39.47 | 77 | 167 | Fc-epsilon receptor signaling pathway | ANGPT1, ARAF, BAD, BTK, CALM3, CAMK2A, CASP9, CD28, CD86, CDKN1A, CHUK, CREB1, CSF2RB, DUSP5, FGF3, FGF4, FGF7, FGFR3, FYN, GRB2, GRIN2A, NRG1, NR4A1, IL2RA, ITPR1, JUN, KIT, MARK3, KITLG, FOXO4, PPP5C, PRKCQ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, PTPRA, RAC1, RAF1, RASA2, RPS6KB2, SHC1, SKP1, UBB, UBE2D2, VAV1, LAT2, FGF23, CUL3, CUL1, IKBKG, PEA15, GRAP2, PSMF1, NRG2, RAPGEF2, GAB2, RBX1, AKAP9, RASA4, PSME3, PSMD14 |
654 | GO:0050905 | 0.01 | 2.83 | 6.59 | 13 | 28 | neuromuscular process | DRD3, FABP7, GLRA1, GRID2, GRIN2A, NRG1, HOXC10, HOXD10, KCNA1, PENK, PTEN, SCN1A, SCN8A |
655 | GO:0030593 | 0.01 | 2.82 | 6.61 | 13 | 28 | neutrophil chemotaxis | CXADR, IFNG, ITGA1, ITGA9, PDE4B, S100A8, S100A9, S100A12, CCL22, CCL25, CX3CL1, XCL2, VAV1 |
656 | GO:0034166 | 0.01 | 2.81 | 6.62 | 13 | 28 | toll-like receptor 10 signaling pathway | CHUK, CREB1, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, RPS6KA1, SKP1, UBB, CUL1, IKBKG, RIPK2 |
657 | GO:0048546 | 0.01 | 2.81 | 6.62 | 13 | 28 | digestive tract morphogenesis | ACVR2B, BMP4, EPHB3, FGFR3, GATA4, IHH, SMAD3, SFRP5, SOX10, SOX11, TP73, WNT11, TP63 |
658 | GO:0065002 | 0.01 | 2.81 | 6.62 | 13 | 28 | intracellular protein transmembrane transport | HSPA4, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX19, PEX5, RTN2, PEX16, TOMM20, C2CD5 |
659 | GO:0048545 | 0.00 | 2.81 | 27.50 | 54 | 119 | response to steroid hormone | ABCA2, ABCA3, ACADS, ALAD, ANXA3, STS, BAX, BCHE, BRCA2, CALM3, CAT, CD4, CDK2, CDKN1A, CDO1, COL1A1, CPS1, CTGF, CTNNA1, ETS1, F3, F7, FGA, GATA4, GATA6, HNMT, IDH1, IGF2, IHH, IL1RN, LCAT, LIPC, SMAD6, NTRK3, PAM, PENK, PTAFR, PTEN, PTGS1, PTPRN, SHC1, SLC9A3, SLC34A1, SPARC, STAT3, STAT5B, TACR3, TAT, SCGB1A1, TRIM25, PRDM2, MBD4, SLIT2, PDCD7 |
660 | GO:0034340 | 0.00 | 2.81 | 9.69 | 19 | 41 | response to type I interferon | ADAR, BST2, UBE2K, IFIT1, IFIT3, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IRF1, IRF5, ISG20, OAS3, PTPN6, SHMT2, SP100, STAT2, SOCS3 |
661 | GO:0048709 | 0.01 | 2.80 | 6.12 | 12 | 26 | oligodendrocyte differentiation | BMP4, BOK, CNP, DRD3, NRG1, NTRK2, PTPRJ, SLC8A3, SOX9, SOX10, TRPC4, VTN |
662 | GO:0042493 | 0.00 | 2.79 | 55.54 | 107 | 235 | response to drug | ABAT, ABCA1, ABCA2, ABCA3, ALAD, ANXA1, ARG1, ASS1, ATP1A1, ATP1A3, ATP4A, ATR, BAD, BAX, BCHE, BGLAP, TSPO, CAT, CCNB1, CCNE1, CD86, CDH1, CDK2, CDK4, CDKN1A, CENPF, CHAT, CHUK, COL1A1, COMT, CPS1, CREB1, CRH, CRHBP, CYBA, CYP2A6, CYP3A4, DAD1, DNMT1, DNMT3B, DPEP1, DRD3, EMX1, EMX2, PTK2B, FYN, GABRA4, GAD1, GATA4, GATA6, GNAS, GPLD1, GRIN2A, HMBS, HMGCS2, HTR2C, ICAM1, IFNG, IGF2, IL10, ITGB1, JUN, JUND, KCNH2, KCNJ11, KCNK3, KCNQ1, LIPC, MGMT, OXCT1, OXTR, P2RX7, PAM, PDE4B, PFAS, PRKAR2B, PTEN, PTN, ABCD3, QDPR, RAD51, RAP2A, REST, RPS6KB1, SLC9A1, SLC34A1, SLC22A1, SLC22A3, SLC22A2, SLC22A5, SNCA, SORD, SRD5A1, SREBF1, SRP14, STAT3, ADAM17, TOP1, TP73, TYMS, SCGB1A1, VEGFB, FOSL1, BCAR3, SOCS3, EFTUD2, ATG5 |
663 | GO:0042770 | 0.00 | 2.78 | 20.56 | 40 | 87 | signal transduction in response to DNA damage | ABL1, ATR, ATRX, BCL3, BRCA2, CASP9, CD44, CDK2, CDKN1A, DDX5, GRB2, HIC1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, SNAI1, SP100, TP73, UBB, WNT1, SMC1A, TP63, CRADD, PSMF1, PSME3, PSMD14 |
664 | GO:0023014 | 0.02 | 2.78 | 4.55 | 9 | 20 | signal transduction by protein phosphorylation | ACVR2B, ACVRL1, BMPR1A, BMPR2, KCNH2, STK10, TYRO3, SLK, OXSR1 |
665 | GO:0021762 | 0.01 | 2.78 | 6.14 | 12 | 26 | substantia nigra development | ACTB, ATP5F1, CALM3, CASP5, CNP, COX6B1, FGFR3, GLUD1, S100A1, ZNF148, DYNLL1, SYNGR3 |
666 | GO:0032760 | 0.01 | 2.78 | 6.14 | 12 | 26 | positive regulation of tumor necrosis factor production | TNFRSF8, CD36, CLU, CYBA, HSPB1, IFNG, IL12B, ISL1, PTAFR, RIPK1, RIPK2, ARHGEF2 |
667 | GO:0045840 | 0.01 | 2.78 | 6.14 | 12 | 26 | positive regulation of mitotic nuclear division | BIRC5, CD28, DRD3, IGF1, IGF1R, IGF2, IL1A, INS, PTEN, RB1, CUL3, DLGAP5 |
668 | GO:0051196 | 0.01 | 2.78 | 6.14 | 12 | 26 | regulation of coenzyme metabolic process | ARNT, IGF1, INS, P2RX7, PDK4, PGAM1, PRKAA1, PRKAG1, SNCA, STAT3, PDHX, OGT |
669 | GO:0051496 | 0.01 | 2.78 | 6.14 | 12 | 26 | positive regulation of stress fiber assembly | CTGF, LPAR1, LIMK1, SMAD3, PFN2, PRKCQ, RAC1, SDC4, WNT11, ARHGEF5, ITGB1BP1, BAG4 |
670 | GO:1990090 | 0.01 | 2.78 | 6.14 | 12 | 26 | cellular response to nerve growth factor stimulus | APP, CREB1, CSNK1D, DNMT1, KAT2A, RAPGEF1, NTRK2, RPS3, SORT1, TRPV1, RAPGEF2, EIF4A3 |
671 | GO:0009891 | 0.03 | 2.78 | 4.03 | 8 | 18 | positive regulation of biosynthetic process | CTGF, F2, FCER2, KDR, PRKAA1, NR2F1, SERPINB7, HDAC6 |
672 | GO:0045665 | 0.00 | 2.77 | 8.71 | 17 | 37 | negative regulation of neuron differentiation | APP, ASCL1, DDX6, EIF4E, FOXA2, ISL1, ITGB1, RAP1GAP, REST, SIX3, SOX3, SOX9, CNTN2, TP73, TTC3, PHOX2B, OLIG2 |
673 | GO:0007369 | 0.00 | 2.77 | 20.09 | 39 | 85 | gastrulation | ACVR2B, APLNR, BMP4, BMPR1A, BMPR2, COL6A1, COL11A1, DUSP1, DUSP5, EPHA2, EXT2, EYA2, GATA4, GATA6, HHEX, FOXA2, IL1RN, ITGA4, ITGA5, ITGAV, ITGB1, LAMA3, SMAD1, SMAD3, OTX2, PRKAR1A, SNAI1, SRF, TAL1, KDM6A, VTN, WNT11, ZBTB17, FZD7, CUL3, CHRD, KLF4, HAND1, ARFRP1 |
674 | GO:0070374 | 0.00 | 2.77 | 20.09 | 39 | 85 | positive regulation of ERK1 and ERK2 cascade | ABL1, ABL2, ANGPT1, ATP6AP1, BMP4, C3, CD36, CD44, CSF1R, CTGF, EDNRA, F2R, PTK2B, FGA, FGF4, FGFR3, FLT4, FSHR, GCG, HMGCR, HTR2C, ICAM1, IL1A, JUN, KDR, PTEN, S100A7, CCL21, CCL22, CCL25, XCL1, CX3CL1, XCL2, VEGFB, FGF23, RIPK2, NRP1, GPR55, RAPGEF2 |
675 | GO:2000021 | 0.00 | 2.77 | 27.89 | 54 | 118 | regulation of ion homeostasis | ABL1, AGTR1, AGTR2, ATP1A2, AVPR2, BAX, BMP4, TSPO, CALM3, CASQ1, CASQ2, CAV3, CD4, COMT, CYBA, DCN, DIAPH1, DRD3, EDNRA, F2, F2R, PTK2B, XCR1, HRC, HTR2C, IL13, ITPR1, KDR, KNG1, SMAD7, NTSR1, P2RX3, P2RX4, P2RX5, P2RX7, PLN, PRKCE, PRKD1, PTPN6, RYR1, RYR2, SCN5A, CCL21, XCL1, SNCA, TRPC1, TRPC3, TRPV1, SLC30A2, AP3D1, GSTO1, AKAP6, ATG5, HCN4 |
676 | GO:0010035 | 0.00 | 2.77 | 30.89 | 60 | 133 | response to inorganic substance | ABAT, ALB, ANXA11, APP, ASCL1, ASS1, ATP12A, BAX, BGLAP, BSG, C3, CALM3, CASP9, CASQ2, CD9, CD36, ENTPD6, CDK4, CLU, CPOX, CPS1, CYB5A, DHFR, ERCC6, FGA, GDI1, HMGCS2, ICAM1, IL1A, LCAT, LIPC, LTA4H, P2RX7, PRDX1, PAM, PCNA, PENK, PLN, PTEN, QDPR, RYR2, S100A8, S100A13, SIPA1, SOD2, SORD, SPARC, TAT, TNNC1, TRPC1, TRPC3, SCGB1A1, SLC30A2, FGF23, SLC14A2, SLC25A12, RGN, PDCD6, SLC25A13, KCNMB2 |
677 | GO:0006303 | 0.00 | 2.76 | 8.74 | 17 | 37 | double-strand break repair via nonhomologous end joining | BARD1, SETMAR, SUMO1, UVRAG, XRCC5, HIST1H4I, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HERC2, RNF8, DCLRE1A, RAD50, PSMD14 |
678 | GO:0071320 | 0.00 | 2.76 | 8.74 | 17 | 37 | cellular response to cAMP | APP, ASS1, CPS1, CRHBP, RAPGEF1, KCNQ1, PENK, PTAFR, SLC8A3, SRD5A1, STC1, AKAP1, AKAP7, AKAP6, RAPGEF2, HCN4, AKAP9 |
679 | GO:0042531 | 0.01 | 2.75 | 5.66 | 11 | 24 | positive regulation of tyrosine phosphorylation of STAT protein | CSF1R, CTF1, FLT3, FYN, HCLS1, IFNA2, IGF1, IL12B, IL13, IL18, ISL1 |
680 | GO:0046651 | 0.00 | 2.75 | 23.81 | 46 | 101 | lymphocyte proliferation | ANXA1, BMP4, CBLB, CD3E, CD4, CD6, CD28, CD86, CD59, CD151, CLC, EFNB1, FLT3, FYN, HPRT1, IFNG, IGF1, IGF2, IHH, IL2RA, IL12B, IL18, IMPDH1, IMPDH2, IDO1, IRF1, ITGAD, LMO1, P2RX7, PRKAR1A, PRKCQ, PTPN6, RAC2, SATB1, XCL1, SFTPD, SOS2, SOX11, STAT5B, TNFSF4, SCGB1A1, PDE5A, TNFSF14, TNFSF9, RIPK2, TNFSF18 |
681 | GO:0010952 | 0.00 | 2.75 | 19.14 | 37 | 81 | positive regulation of peptidase activity | APAF1, APP, BAD, BAX, BOK, CASP9, COL4A3, CTGF, CTSH, F2R, F3, FBLN1, HIP1, IFI16, SMAD3, P2RX1, PCOLCE, REST, RPS3, S100A8, S100A9, SNCA, TRAF2, PICALM, TRADD, RIPK1, CRADD, TNFSF10, TNFRSF10B, TNFRSF10A, EIF2AK3, TNFSF15, CASP8AP2, PDCD6, BCL2L11, PSME3, PSMD14 |
682 | GO:0010862 | 0.01 | 2.74 | 5.67 | 11 | 24 | positive regulation of pathway-restricted SMAD protein phosphorylation | ACVRL1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, GDF9, INHA, TTK, GDF15 |
683 | GO:2001237 | 0.00 | 2.74 | 8.26 | 16 | 35 | negative regulation of extrinsic apoptotic signaling pathway | BCL2L1, CTNNA1, CX3CR1, CTTN, FYN, NRG1, IGF1, IL1A, ITGAV, RPS6KB1, CX3CL1, SCG2, RIPK1, NRP1, RB1CC1, PSME3 |
684 | GO:0034134 | 0.00 | 2.73 | 8.27 | 16 | 35 | toll-like receptor 2 signaling pathway | BTK, CD36, CHUK, CREB1, CYBA, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, RPS6KA1, SKP1, UBB, CUL1, IKBKG, RIPK2 |
685 | GO:0035666 | 0.00 | 2.73 | 8.27 | 16 | 35 | TRIF-dependent toll-like receptor signaling pathway | BIRC3, CHUK, CREB1, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, RPS6KA1, SKP1, UBB, UBE2D2, CUL1, IKBKG, RIPK1, RIPK2 |
686 | GO:2000134 | 0.00 | 2.73 | 16.07 | 31 | 68 | negative regulation of G1/S transition of mitotic cell cycle | CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, RB1, RPA2, SMARCA4, TP73, UBB, TP63, CRADD, PSMF1, PSME3, PSMD14, CTDSPL |
687 | GO:0007045 | 0.00 | 2.73 | 10.87 | 21 | 46 | cell-substrate adherens junction assembly | ACTN1, ACVRL1, ARHGAP6, DAPK3, EFNA5, CTTN, PTK2B, HRG, KDR, SMAD3, PTEN, PTK2, PTPRJ, RAC1, SDC4, SLC9A1, TRIP6, TSC1, ARHGEF7, ITGB1BP1, SLK |
688 | GO:0045787 | 0.01 | 2.73 | 7.22 | 14 | 31 | positive regulation of cell cycle | ASCL1, CCNC, CCNT2, OVOL1, PIM1, RARA, SETMAR, STIL, SRPK2, TRIM21, ADAM17, FOSL1, CCPG1, BCL2L11 |
689 | GO:0051704 | 0.00 | 2.72 | 52.34 | 101 | 236 | multi-organism process | ABCA1, ABL1, ADH5, ALAD, ANXA3, KLK3, ASS1, ATP4B, BCL3, BCR, BPI, TSPO, CASP9, CD6, CD8A, TNFRSF8, TNFSF8, ENTPD2, CDK6, CEBPE, CHUK, CLU, CNP, CPS1, CRP, DCN, DDX1, DNMT1, F2R, F3, FCN2, FGA, FGR, CXCL3, HMGCS2, HP, HRG, HSPB1, IFIT3, IFNA5, IFNA13, IFNA17, IFNA21, IFNGR1, IFNW1, RBPJ, IL10RA, IL12RB2, IL13, IL18, IRAK1, IRAK2, IRF1, IRF5, JUND, KCNJ8, SERPINE1, PDE4B, PF4V1, CFP, PRG2, PRKCE, PTGER1, PTGER2, UPF1, S100A7, S100A8, S100A9, S100A12, CCL22, CXCL6, CXCL5, XCL1, SELE, SELP, SFTPD, SNCA, SPARC, ADAM17, TNFRSF1B, TPT1, TNFSF4, VIL1, FZD5, HIST2H2BE, OGT, PPM1D, PARG, RIPK2, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, SOCS3, DDX21, IL27RA, ADAMTS4, LITAF, NR1H4, ABCC9, IL18BP |
690 | GO:0008217 | 0.00 | 2.72 | 15.06 | 29 | 64 | regulation of blood pressure | ACVRL1, ADH5, ADRA1B, AGTR1, ATP1A1, ATP1A2, AVPR1B, AVPR2, CACNA1B, CYBA, CYP11B1, ACE, EDNRA, EMP2, F2R, GCGR, NRG1, OXTR, P2RX1, P2RX4, PCSK5, PTGS1, RENBP, ACSM3, SGK1, SLC2A5, TACR3, TNNI3, ATP6AP2 |
691 | GO:0007588 | 0.02 | 2.71 | 5.18 | 10 | 22 | excretion | AQP5, AQP6, CLCNKA, CLCNKB, GUCA2B, KCNJ1, SCNN1B, SCNN1G, SCTR, SLC12A1 |
692 | GO:0014812 | 0.00 | 2.70 | 7.80 | 15 | 33 | muscle cell migration | ANXA1, ACE, LPAR1, F3, IGF1, IGFBP3, ILK, P2RY2, P2RY6, SERPINE1, RPS6KB1, VTN, NRP1, ITGB1BP1, SLIT2 |
693 | GO:0032945 | 0.00 | 2.70 | 7.80 | 15 | 33 | negative regulation of mononuclear cell proliferation | PRDM1, BMP4, CBLB, CTLA4, IHH, IL2RA, IL10, IDO1, PRKAR1A, PTPN6, XCL1, SFTPD, SOX11, SCGB1A1, PDE5A |
694 | GO:0002381 | 0.02 | 2.70 | 5.20 | 10 | 22 | immunoglobulin production involved in immunoglobulin mediated immune response | CD28, IFNG, IL10, XCL1, STAT6, TNFSF4, UNG, RNF8, EXO1, IL27RA |
695 | GO:0007595 | 0.02 | 2.70 | 5.20 | 10 | 22 | lactation | APRT, ATP2B2, CDO1, CHUK, CREB1, GHRHR, OXTR, PAM, STAT5B, EIF2AK3 |
696 | GO:0045070 | 0.02 | 2.70 | 5.20 | 10 | 22 | positive regulation of viral genome replication | ADAR, CD28, NR5A2, IFIT1, PPIB, PPID, SRPK2, STAU1, TOP2A, VAPB |
697 | GO:0046461 | 0.02 | 2.70 | 5.20 | 10 | 22 | neutral lipid catabolic process | APOH, DAGLA, CPS1, FABP2, FABP7, GPLD1, LIPC, LIPE, PRKACB, PRKACG |
698 | GO:0060976 | 0.02 | 2.70 | 5.20 | 10 | 22 | coronary vasculature development | PRDM1, DNM2, GATA6, GPC3, SMAD6, PCSK5, SRF, VEGFB, NRP1, SNX17 |
699 | GO:2000514 | 0.02 | 2.70 | 5.20 | 10 | 22 | regulation of CD4-positive, alpha-beta T cell activation | ANXA1, CD86, IFNG, IL12B, PRKCQ, RARA, XCL1, TNFSF4, RIPK2, TNFSF18 |
700 | GO:0045981 | 0.00 | 2.70 | 15.13 | 29 | 64 | positive regulation of nucleotide metabolic process | ABCA1, ARNT, AVPR2, CALM3, CRH, DRD5, EDNRA, FSHR, FZD2, GCG, GHRHR, GNAS, GUCA1A, GUCA2A, GUCA2B, IGF1, INS, NTRK2, P2RX7, P2RY11, PRKAA1, RAF1, RCVRN, STAT3, VIP, VIPR2, WFS1, AKAP12, GUCA1C |
701 | GO:0018130 | 0.01 | 2.69 | 7.14 | 14 | 33 | heterocycle biosynthetic process | ALAD, ALAS2, TSPO, COX15, CPOX, CPS1, HMBS, IDO1, OAT, PYCR1, QDPR, UROS, ALDH4A1, ABCB6 |
702 | GO:0002824 | 0.00 | 2.68 | 9.93 | 19 | 42 | positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | ANXA1, C3, CD4, CD28, FCER2, HPX, IFNG, IL12B, P2RX7, PRKCQ, PVR, XCL1, STAT6, TRAF2, TNFSF4, UNG, FZD5, RIPK2, IL27RA |
703 | GO:0046903 | 0.01 | 2.68 | 5.69 | 11 | 25 | secretion | CACNB4, ACE, EDNRA, KCNQ1, P2RX4, PRKCI, SGK1, STC1, TPD52, TRPC4, SLC9A3R1 |
704 | GO:0010676 | 0.01 | 2.68 | 7.32 | 14 | 31 | positive regulation of cellular carbohydrate metabolic process | ADRA1B, BAD, GCG, KAT2A, GPLD1, HRH1, IGF2, NTSR1, PRKCE, PTAFR, SNCA, DYRK2, RGN, EPM2AIP1 |
705 | GO:0051436 | 0.00 | 2.68 | 16.78 | 32 | 71 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | BUB1B, CCNB1, CDC20, CDC27, CENPF, DUSP1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, TTK, UBB, ZNF207, CDC23, CDC16, ZW10, PSMF1, PSME3, PSMD14 |
706 | GO:0071156 | 0.00 | 2.68 | 16.78 | 32 | 71 | regulation of cell cycle arrest | CDK2, CDK4, CDKN1A, FAP, GATA6, FOXO4, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, SETMAR, TP73, UBB, RNF112, CRADD, PHOX2B, PSMF1, PSME3, PSMD14 |
707 | GO:0000186 | 0.00 | 2.68 | 32.14 | 61 | 136 | activation of MAPKK activity | ANGPT1, ARAF, BMP4, CALM3, CAMK2A, CRKL, CSF2RB, DUSP5, ERCC6, F2R, FGF3, FGF4, FGF7, FGFR3, FLT1, FYN, GRB2, RAPGEF1, GRIN2A, GRM1, NRG1, IL2RA, KIT, MARK3, KITLG, MAP3K11, PPP5C, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTK2, PTPRA, RAF1, RASA2, SHC1, UBB, FGF23, CUL3, PEA15, PSMF1, NRG2, RAPGEF2, RBX1, AKAP9, RASA4, PSME3, PSMD14 |
708 | GO:0001756 | 0.01 | 2.67 | 7.33 | 14 | 31 | somitogenesis | BMPR1A, CDX2, EP300, KAT2A, FOXA2, SMAD3, MEOX2, OTX2, PAX3, PCDH8, KDM6A, XRCC2, RGS20, ZEB2 |
709 | GO:0017158 | 0.01 | 2.67 | 7.33 | 14 | 31 | regulation of calcium ion-dependent exocytosis | ARF1, CACNA1A, B4GALT1, GLRA1, PFN2, SEPT5, RAB5A, REST, SPINK1, STXBP3, SYN1, SYT1, SYT4, SYT7 |
710 | GO:0034332 | 0.00 | 2.67 | 18.91 | 36 | 80 | adherens junction organization | ACTB, ACTN1, ACVRL1, ANG, ARHGAP6, CDH1, CDH6, CDH7, CDH8, CDH9, CDH10, CDH12, CDH15, CTNNA1, DAPK3, EFNA5, CTTN, PTK2B, HRG, KDR, SMAD3, SMAD7, PTEN, PTK2, PTPRJ, PVR, RAC1, SDC4, SLC9A1, TBCD, TRIP6, TSC1, NUMB, ARHGEF7, ITGB1BP1, SLK |
711 | GO:0050852 | 0.00 | 2.67 | 23.16 | 44 | 98 | T cell receptor signaling pathway | CACNB4, CBLB, CD3D, CD3E, CD3G, CD4, CD28, CHUK, FYB, FYN, KCNN4, PDE4B, PRKCQ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTPN6, PTPRJ, SKP1, UBB, UBE2D2, CUL1, IKBKG, RIPK2, GRAP2, PSMF1, BCAR1, PSME3, PSMD14 |
712 | GO:0034097 | 0.00 | 2.66 | 8.81 | 17 | 39 | response to cytokine | ADAM10, AVPR2, BCL2L1, CCNE1, FOXA2, ITIH4, JUN, JUND, OXTR, RARA, RPS6KB1, SPARC, SRF, TYMS, SCGB1A1, FOSL1, KYNU |
713 | GO:0051149 | 0.00 | 2.66 | 9.45 | 18 | 40 | positive regulation of muscle cell differentiation | ABL1, BMP4, CAV3, CDH15, CTH, CTNNA1, FLT3LG, NRG1, IGFBP3, RBPJ, ILK, NTN3, RBM4, SMARCD3, NR2C2, TNFSF14, AKAP6, GDF15 |
714 | GO:0006144 | 0.03 | 2.65 | 4.72 | 9 | 20 | purine nucleobase metabolic process | ACPP, ADSS, AMPD1, AMPD2, CAT, GPX1, IMPDH1, IMPDH2, PFAS |
715 | GO:0002204 | 0.03 | 2.65 | 4.73 | 9 | 20 | somatic recombination of immunoglobulin genes involved in immune response | CD28, IFNG, IL10, STAT6, TNFSF4, UNG, RNF8, EXO1, IL27RA |
716 | GO:0002323 | 0.03 | 2.65 | 4.73 | 9 | 20 | natural killer cell activation involved in immune response | IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IL12B, RAB27A, STX11 |
717 | GO:0006271 | 0.03 | 2.65 | 4.73 | 9 | 20 | DNA strand elongation involved in DNA replication | FEN1, PCNA, PRIM2, RFC3, RFC4, RFC5, RPA2, RPA3, GINS1 |
718 | GO:0007628 | 0.03 | 2.65 | 4.73 | 9 | 20 | adult walking behavior | CACNA1A, CACNB4, CTNS, GLRA1, KCNJ10, SCN1A, SCN8A, CNTN2, ZIC1 |
719 | GO:0042168 | 0.03 | 2.65 | 4.73 | 9 | 20 | heme metabolic process | ALAD, ALAS2, BLVRA, TSPO, COX15, CPOX, HMBS, HPX, UROS |
720 | GO:0050690 | 0.03 | 2.65 | 4.73 | 9 | 20 | regulation of defense response to virus by virus | ARF1, CD4, CD28, AP1S1, AP2S1, FYN, RAC1, AP1M1, AP1M2 |
721 | GO:0050931 | 0.03 | 2.65 | 4.73 | 9 | 20 | pigment cell differentiation | CD63, GNAQ, KIT, KITLG, RAB27A, SOX10, AP1M1, AP3D1, ZEB2 |
722 | GO:0070266 | 0.03 | 2.65 | 4.73 | 9 | 20 | necroptotic process | BIRC3, TRAF2, UBB, TRADD, RIPK1, TNFSF10, TNFRSF10B, TNFRSF10A, ARHGEF2 |
723 | GO:0050729 | 0.00 | 2.65 | 13.71 | 26 | 58 | positive regulation of inflammatory response | AGTR1, C3, CD6, CD28, CNR1, EDNRA, FFAR3, IL12B, IL18, IDO1, KLKB1, SERPINE1, RPS19, S100A8, S100A9, S100A12, XCL1, CX3CL1, STAT5B, XCL2, TNFRSF1A, TNFSF4, VAMP8, TNFSF18, IL1RL1, CLOCK |
724 | GO:0090132 | 0.00 | 2.64 | 32.38 | 61 | 137 | epithelium migration | ACVRL1, AGTR2, ANGPT1, ANGPT2, ANXA3, APOH, BMP4, BMPR2, KRIT1, CD63, CTSH, DCN, DPP4, EFNA1, EGR3, EPHA2, EMP2, ETS1, PTK2B, FAP, FGF4, FGF7, FLT4, GPLD1, GPX1, NR4A1, HRG, HSPB1, IFNG, ITGB1, JUN, KDR, KIT, KRT2, SERPINF1, PFN2, PRCP, PRKCE, PRKD1, PRKX, PTEN, PTK2, PTPRR, S100A2, SOX9, SP100, SPARC, SRF, STC1, NR2F2, VIL1, SCG2, NRP2, NRP1, ITGB1BP1, KLF4, SLIT2, BCAR1, ZEB2, HDAC6, PDCD6 |
725 | GO:0034146 | 0.01 | 2.64 | 6.85 | 13 | 29 | toll-like receptor 5 signaling pathway | CHUK, CREB1, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, RPS6KA1, SKP1, UBB, CUL1, IKBKG, RIPK2 |
726 | GO:0031325 | 0.00 | 2.63 | 10.31 | 20 | 48 | positive regulation of cellular metabolic process | ABAT, ACACB, APOH, BNIP3L, CD63, COMT, FGR, GHSR, HPRT1, PIP4K2A, RAB1A, SELE, NR2F1, UVRAG, ZNF16, PICK1, ATG5, TMEM59, HDAC6, RAMP3 |
727 | GO:0001525 | 0.00 | 2.63 | 28.09 | 53 | 120 | angiogenesis | ANG, ANGPT1, BAX, BMP4, KLF5, COL15A1, CSPG4, CTGF, TYMP, S1PR1, EDNRA, EFNA1, EGR3, EPHA2, EMP2, EPHB1, EPHB2, EPHB3, FAP, FLT4, GPLD1, NR4A1, RBPJ, IHH, IL18, ITGAV, ITGB1, JUN, MEOX2, NRCAM, PRKX, PTEN, PTK2, S100A7, SHB, SHC1, SP100, SRPK2, TAL1, VEZF1, FZD5, SCG2, FZD8, ADAM15, NRP2, NRP1, SLIT2, NRXN3, NRXN1, HAND1, EIF2AK3, SLC12A6, WASF2 |
728 | GO:0042311 | 0.00 | 2.63 | 8.98 | 17 | 38 | vasodilation | AGTR1, AGTR2, CPS1, CRP, ACE, GPX1, HMGCR, INS, ITGA1, KCNJ8, KNG1, P2RX4, P2RY2, PTAFR, SOD2, VIP, ATG5 |
729 | GO:0070098 | 0.00 | 2.63 | 8.98 | 17 | 38 | chemokine-mediated signaling pathway | CCR3, CCR8, CX3CR1, PTK2B, XCR1, GPR17, CXCL3, PF4V1, CCL21, CCL22, CCL25, CXCL6, CXCL5, XCL1, CX3CL1, XCL2, SLIT2 |
730 | GO:0007267 | 0.00 | 2.62 | 60.24 | 113 | 264 | cell-cell signaling | ACVR2B, ADAM10, ADRA1B, AGTR1, AGTR2, ANXA1, ANXA5, ARL2, ARNTL, ASIP, BAD, BLK, BMP3, BMP4, BST2, CD86, TNFSF8, CD70, ADGRE5, CTF1, CTGF, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EPHA5, FGA, FGF3, FGF4, FGF7, FGFR3, FZD2, GALR1, GATA4, GCG, GDF9, GHRHR, GHSR, GJA3, GJA4, GJB1, GLUD1, GNAS, GPLD1, FFAR1, FFAR3, GRB2, HGF, HMGCR, FOXA2, IAPP, IFNA2, IHH, IK, IL1RN, IL10, IL13, IL18, INHA, INS, ISL1, ITPR1, NTF4, OXCT1, PCSK5, PGR, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PTGS1, PTPRN, RAB1A, REST, RFX3, S100A9, CCL21, CCL22, CXCL6, CXCL5, XCL1, SOX11, SREBF1, STXBP3, HNF1A, KLF10, TRPM2, VIP, VIPR2, WNT1, SEMA3B, FGF23, FZD4, TP63, VAMP8, TNFSF10, TNFSF9, NRP1, WISP3, ARHGEF7, TNFSF18, SYT7, HMGN3, GRAP2, EIF2AK3, GDF15, CXCL14, CLOCK, NR1H4, FGFBP1, CHST4 |
731 | GO:0032388 | 0.00 | 2.62 | 14.82 | 28 | 63 | positive regulation of intracellular transport | ABL1, ARF1, BAD, BAX, CALM3, CD4, DNM1, EDNRA, F2, F2R, FGR, IL13, NTSR1, P2RX3, P2RX4, P2RX5, P2RX7, XCL1, SNCA, TRPC1, TRPC3, YWHAZ, DYNLL1, VAMP8, SYNJ1, GSTO1, GAB2, BCL2L11 |
732 | GO:0050731 | 0.00 | 2.62 | 14.82 | 28 | 63 | positive regulation of peptidyl-tyrosine phosphorylation | ABL1, ANGPT1, CD3E, CD4, CD36, CD44, CSPG4, ACE, EFNA1, EFNA5, ERCC6, PTK2B, FGF7, HGF, NRG1, ICAM1, IGF2, INS, ITGA5, ITGB1, KITLG, ADAM17, VEGFB, VTN, RIPK2, NRP1, UNC119, ARHGEF2 |
733 | GO:0030168 | 0.00 | 2.62 | 35.21 | 66 | 149 | platelet activation | ABAT, ACTB, ACTN1, ALB, APP, AXL, DAGLA, CALM3, CD9, CD36, ENTPD2, CD63, CLU, COL1A1, CSRP1, DGKB, F2, F2R, F2RL2, FGA, FYN, GNA15, GNAI1, GNAQ, GNAS, GP1BA, GP9, GRB2, HGF, HRG, HSPB1, IGF1, IGF2, ILK, ITPR1, KNG1, LAMP2, P2RX1, SERPINE1, PF4V1, PRKCE, PRKCQ, PSAP, PTK2, PTPN6, RAC1, RAC2, RAF1, RAP2B, CX3CL1, SELP, SHC1, SPARC, SRF, STXBP3, TRPC3, TUBA4A, TYRO3, VAV1, VEGFB, YWHAZ, FZD6, DGKI, BCAR1, GNA14, ABCC4 |
734 | GO:0002274 | 0.00 | 2.61 | 19.14 | 36 | 81 | myeloid leukocyte activation | ADAM10, ANXA3, BCR, BPI, CD86, CD37, CLU, CNR1, CX3CR1, FGR, FLT3LG, RBPJ, IL10, IL13, IL13RA2, JUN, KIT, PRKCE, PTAFR, PTPRE, RAC2, S100A12, S100A13, CX3CL1, SNCA, STXBP2, STXBP3, TYROBP, TRPV1, LAT2, VAMP8, STX11, TNFSF9, IL1RL1, GAB2, DHRS2 |
735 | GO:0071347 | 0.00 | 2.60 | 10.63 | 20 | 45 | cellular response to interleukin-1 | BYSL, HSPA9, ICAM1, IL1R1, IL1RN, IRAK1, IRAK2, P2RY2, PPP4C, PTGIS, UPF1, CCL21, CCL22, CCL25, XCL1, CX3CL1, SOX9, XCL2, YY1, RPS6KA4 |
736 | GO:0045776 | 0.04 | 2.60 | 4.24 | 8 | 18 | negative regulation of blood pressure | ABAT, CNR1, CRH, DRD3, DRD5, FFAR3, GUCA2B, PTAFR |
737 | GO:0071417 | 0.00 | 2.60 | 72.44 | 134 | 310 | cellular response to organonitrogen compound | ANGPT1, ANXA5, APRT, ARAF, ARG1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, CALM3, CAMK2A, CDH1, CDK2, CREB1, CSF2RB, CSH1, CTNNA1, CYP11B1, DIAPH1, DUSP5, EIF4E, FBN1, FGF3, FGF4, FGF7, FGFR3, FYN, GCG, GCGR, GH2, GHRHR, GHSR, GNG3, GNG10, GNRHR, GPLD1, FFAR3, GRB2, GRIN2A, NRG1, NR4A1, HRH1, IGF1, IGF1R, IGF2, IL2RA, INS, KIT, MARK3, KITLG, FOXO4, YBX1, P2RX4, P2RY2, P2RY11, PDK4, PPP5C, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCI, PRKCQ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTK2, PTPN6, PTPRA, PTPRE, RAF1, RANGAP1, RASA2, RHEB, RPS6, RPS6KB1, RXRA, SRSF5, SHC1, SHMT1, SLC2A4, SOX9, SREBF1, STAT3, STAT5B, ADAM17, KLF10, HSP90B1, TSC1, UBB, USF1, WNT1, FGF23, CUL3, OGT, PIK3R3, PEA15, RIPK2, SOCS3, ATP6V0D1, IL1RL1, ARHGEF2, KLF4, GLP2R, SLIT2, PSMF1, NRG2, ATP6V1G1, BCAR1, C2CD5, NR1H4, RBX1, RASA4, PSME3, PSMD14 |
738 | GO:0042130 | 0.01 | 2.59 | 6.38 | 12 | 27 | negative regulation of T cell proliferation | BMP4, CBLB, IHH, IL2RA, IL10, IDO1, PRKAR1A, PTPN6, XCL1, SFTPD, SCGB1A1, PDE5A |
739 | GO:0060415 | 0.01 | 2.59 | 6.38 | 12 | 27 | muscle tissue morphogenesis | COL11A1, S1PR1, FZD2, NRG1, RBPJ, ISL1, SMAD7, RXRA, RYR2, TNNC1, TNNI3, HAND1 |
740 | GO:0008283 | 0.00 | 2.59 | 48.80 | 92 | 222 | cell proliferation | ADRA1B, ALK, AMBN, RERE, TNFRSF17, BOK, ZFP36L2, BST2, BUB1B, BYSL, DAGLA, CD5, TNFSF8, CD70, CDK11B, CDC25A, CDC25C, CDC27, CDK3, CENPF, CHRM3, CHUK, CKS1B, CLK1, CSE1L, CSPG4, DKC1, DMBT1, E4F1, EPHA2, ELN, EML1, EMX2, EPHB1, EPS15, ERG, ETV6, GPC4, GCG, KAT2A, GNAT1, HDGF, HLCS, IFI16, IL15RA, INSIG1, ISG20, KCNA1, KRT2, MAP3K11, PA2G4, PRDX1, PCM1, PCNA, PENK, PIM1, PPP1R8, PRKX, RAC1, REG1B, RPS6KA1, RPS27, RRM1, RYK, SETMAR, STIL, SIPA1, FSCN1, STAT4, TACC1, TSPY1, TYMS, TYR, UBE2L3, PICALM, FZD6, FZD9, GFI1B, BLZF1, NUMB, CDC16, EIF2S2, USP8, ARHGEF1, AURKB, COPS2, LIPG, BCAR1, DLGAP5, GINS1, ZEB2, COL4A3BP |
741 | GO:0001662 | 0.04 | 2.59 | 4.25 | 8 | 18 | behavioral fear response | CRH, DBI, DPP4, EIF4E, GABRA5, HTR2C, PENK, RPS6KB1 |
742 | GO:0008299 | 0.04 | 2.59 | 4.25 | 8 | 18 | isoprenoid biosynthetic process | ALDH1A3, FDFT1, FDPS, HMGCR, HMGCS2, RBP1, AKR1C3, DHRS9 |
743 | GO:0021587 | 0.04 | 2.59 | 4.25 | 8 | 18 | cerebellum morphogenesis | ABL1, ABL2, ATP2B2, CACNA1A, GRID2, WNT1, USP9X, NRXN1 |
744 | GO:0032633 | 0.04 | 2.59 | 4.25 | 8 | 18 | interleukin-4 production | CD3E, CD86, RBPJ, PRG2, PRKCQ, RARA, TNFSF4, SCGB1A1 |
745 | GO:0034105 | 0.04 | 2.59 | 4.25 | 8 | 18 | positive regulation of tissue remodeling | ATP6AP1, BAX, ERG, FSHB, B4GALT1, HRG, IL12B, IL18 |
746 | GO:0040018 | 0.04 | 2.59 | 4.25 | 8 | 18 | positive regulation of multicellular organism growth | BBS4, CREB1, GHRHR, GHSR, IGF2, PPIB, STAT5B, VIL1 |
747 | GO:0045744 | 0.04 | 2.59 | 4.25 | 8 | 18 | negative regulation of G-protein coupled receptor protein signaling pathway | BICD1, DNM1, DNM2, DRD3, PALM, RGS12, RGS13, SNCA |
748 | GO:0048333 | 0.04 | 2.59 | 4.25 | 8 | 18 | mesodermal cell differentiation | BMP4, BMPR1A, EYA2, ITGB1, SMAD1, TAL1, KDM6A, KLF4 |
749 | GO:0051293 | 0.04 | 2.59 | 4.25 | 8 | 18 | establishment of spindle localization | CENPA, DYNC1H1, LLGL2, NUMA1, DYNLT1, ARHGEF2, ZW10, SPRY1 |
750 | GO:0051646 | 0.04 | 2.59 | 4.25 | 8 | 18 | mitochondrion localization | ALB, ATP2A1, KAT2A, OPA1, UBB, UXT, OGT, HDAC6 |
751 | GO:0070423 | 0.04 | 2.59 | 4.25 | 8 | 18 | nucleotide-binding oligomerization domain containing signaling pathway | BIRC3, XIAP, CHUK, IRAK1, IRAK2, UBB, IKBKG, RIPK2 |
752 | GO:1902042 | 0.04 | 2.59 | 4.25 | 8 | 18 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | FGA, GPX1, HGF, ICAM1, SERPINE1, RAF1, PEA15, ARHGEF2 |
753 | GO:0007584 | 0.00 | 2.59 | 11.71 | 22 | 50 | response to nutrient | ABCA1, AHCY, ALB, APAF1, ASS1, BRCA2, CD3E, CHAT, CNR1, DAD1, GCGR, HMGCR, HMGCS2, IGF1, OXCT1, PTEN, RPS6KB1, SUOX, OGT, HAT1, AKR1C3, LIPG |
754 | GO:0002700 | 0.00 | 2.58 | 12.29 | 23 | 52 | regulation of production of molecular mediator of immune response | ANGPT1, BST2, BTK, CD28, CD36, CD37, CLC, FFAR3, HPX, IFNA2, IFNG, IL10, IL13, IL13RA2, XCL1, STAT6, TRAF2, TNFSF4, UNG, FZD5, IL27RA, ATG5, TRIL |
755 | GO:0048634 | 0.00 | 2.58 | 12.29 | 23 | 52 | regulation of muscle organ development | ARNTL, BMP4, CAV3, CCNB1, CENPF, CXADR, DDX5, TSC22D3, FGF3, GATA4, GATA6, NRG1, HMGCR, RBPJ, KCNK2, SMAD3, PRKAA1, RPS6KB1, TP73, USP2, CTDP1, AKAP6, NR1D2 |
756 | GO:1901861 | 0.00 | 2.58 | 12.29 | 23 | 52 | regulation of muscle tissue development | ARNTL, BMP4, CAV3, CCNB1, CENPF, CXADR, DDX5, TSC22D3, FGF3, GATA4, GATA6, NRG1, HMGCR, RBPJ, KCNK2, SMAD3, PRKAA1, RPS6KB1, TP73, USP2, CTDP1, AKAP6, NR1D2 |
757 | GO:0043406 | 0.01 | 2.58 | 8.00 | 15 | 34 | positive regulation of MAP kinase activity | PTK2B, FLT1, FLT3, ILK, KITLG, RPS3, S100A12, TPD52L1, TRAF2, FZD5, ARHGEF5, FZD4, FZD8, PDE5A, ZEB2 |
758 | GO:0032869 | 0.01 | 2.58 | 7.44 | 14 | 32 | cellular response to insulin stimulus | APRT, CDK2, GHRHR, GHSR, FFAR3, HMGCS2, IGF1, PRKCI, RXRA, SRSF5, SLC2A4, SLC9A1, SRD5A1, USF1 |
759 | GO:0051591 | 0.01 | 2.58 | 8.00 | 15 | 34 | response to cAMP | BSG, CDK2, CDO1, COL1A1, DUSP1, PTK2B, HMGCS2, JUN, JUND, PTPRN, PYGM, SPARC, SREBF1, TYR, FOSL1 |
760 | GO:0033555 | 0.00 | 2.57 | 10.16 | 19 | 43 | multicellular organismal response to stress | TSPO, CACNA1A, CACNA1B, COMT, CRH, DBH, DBI, DPP4, EIF4E, GABRA5, GJA4, HMGCS2, HTR2C, IDO1, P2RX3, PENK, PTEN, RPS6KB1, TRPV1 |
761 | GO:0043044 | 0.00 | 2.57 | 10.16 | 19 | 43 | ATP-dependent chromatin remodeling | ACTB, ACTL6A, CENPA, CHD4, CENPI, HNRNPC, SMARCA1, SMARCA4, SMARCE1, HIST1H4I, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, RUVBL1, RNF8 |
762 | GO:0044057 | 0.00 | 2.57 | 17.04 | 32 | 74 | regulation of system process | ABAT, ANXA6, CNN1, CRH, CRHBP, DAPK3, CTTN, FLT1, GALR1, GDF9, GHSR, GTF2I, IGF1, INHA, KCNA1, KISS1, PPP1R12B, RPS6KB1, SGK1, SLC22A5, SRF, TNNC2, TNNC1, TNNI2, TRPC3, NR1H2, TRPV1, AKAP1, PHOX2B, CTDP1, KLF4, AKAP6 |
763 | GO:0071214 | 0.00 | 2.57 | 25.74 | 48 | 110 | cellular response to abiotic stimulus | ASCL1, ATF4, ATR, BAX, BCL2L1, TSPO, CALM3, CASP9, CDC25A, CDKN1A, CNGA1, CRY2, DNM2, ELK1, EP300, ERCC4, GNGT1, GPLD1, GRB2, GUCA1A, GUCY2F, GUCY2D, IFI16, INSRR, MGMT, PCK1, PCNA, PPID, PRKCQ, PTAFR, PTN, RAD51, RCVRN, RPGR, SCN2A, SIPA1, SLC2A4, SLC12A1, TP73, XRCC5, YY1, TP63, ARHGEF2, AURKB, CLOCK, GUCA1C, OXSR1, SLC12A6 |
764 | GO:0002758 | 0.00 | 2.57 | 15.53 | 29 | 66 | innate immune response-activating signal transduction | CALM3, EP300, FYN, ICAM2, ITPR1, PRKACB, PRKACG, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, RAF1, UBA3, PSMF1, PSME3, PSMD14 |
765 | GO:0072507 | 0.00 | 2.57 | 51.52 | 95 | 218 | divalent inorganic cation homeostasis | ABL1, ABL2, ADRA1B, AGTR1, ANXA6, APP, ATP1A2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, AVPR1B, BAX, BMP4, CACNA1A, CACNB4, CALM3, CASQ1, CASQ2, CAV3, CD4, CD36, CD52, CCR3, CCR8, CYBA, DIAPH1, DRD3, DRD5, S1PR1, LPAR1, EDNRA, F2, F2R, PTK2B, GALR1, GNA15, GNAT2, GNG3, XCR1, GRINA, GRM1, GTF2I, HEXB, HRC, HTR2C, IL13, ITGB1, ITPR1, KCNA1, KCNK3, KDR, KISS1, KNG1, NTSR1, OXTR, P2RX3, P2RX4, P2RX5, P2RX7, P2RY2, P2RY4, PLN, PRKCE, PRKD1, PTPN6, PYGM, RYR1, RYR2, S100A8, S100A9, CCL21, XCL1, SLC8A3, SNCA, STC1, TNNI3, TPT1, HSP90B1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, TRPV1, WFS1, SLC30A2, S1PR4, INPP4B, AP3D1, RGN, VAPB, GSTO1, AKAP6, ATG5 |
766 | GO:0009791 | 0.00 | 2.56 | 13.94 | 26 | 59 | post-embryonic development | ACVR2B, ATRX, BAX, PRDM1, BMP4, CLPS, DHCR7, EMX1, FBN1, EFEMP1, FLT3, GNAQ, GNAS, HMGN1, INPPL1, ITPR1, KCNJ1, KDR, LLGL2, TBCE, TP73, FZD5, USP9X, DLK1, KLF4, BCL2L11 |
767 | GO:0016259 | 0.00 | 2.56 | 13.94 | 26 | 59 | selenocysteine metabolic process | FAU, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, RPL14, RPL23, EIF4A3 |
768 | GO:0035567 | 0.01 | 2.56 | 8.04 | 15 | 34 | non-canonical Wnt signaling pathway | ABL1, ABL2, CSNK1D, GPC4, FZD2, RAC1, RYK, SFRP5, WNT11, FZD5, FZD4, FZD6, FZD7, FZD8, FZD9 |
769 | GO:0060135 | 0.01 | 2.56 | 8.04 | 15 | 34 | maternal process involved in female pregnancy | ANGPT2, ARG1, PRDM1, BMPR2, BSG, CNR1, GHSR, IHH, ITGB1, PAM, PGR, PTGIS, RXRA, STC1, NR2F2 |
770 | GO:0060291 | 0.01 | 2.56 | 8.04 | 15 | 34 | long-term synaptic potentiation | CREB1, CRH, CX3CR1, DBI, PTK2B, GFAP, GRIN2A, NTRK2, PTEN, PTN, SLC8A3, SNAP25, SNCA, STAU1, TNR |
771 | GO:0033209 | 0.00 | 2.56 | 26.94 | 50 | 114 | tumor necrosis factor-mediated signaling pathway | BIRC3, TNFRSF17, TNFRSF8, CD70, CHUK, EDA, PTK2B, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, SKP1, ADAM17, TNFRSF1A, TNFRSF1B, TRAF1, TRAF2, TNFSF4, UBB, NSMAF, CUL1, IKBKG, TRADD, RIPK1, TNFSF14, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, TAX1BP1, TNFSF18, UBA3, PSMF1, BAG4, TNFSF15, PSME3, PSMD14 |
772 | GO:0034614 | 0.02 | 2.56 | 5.89 | 11 | 25 | cellular response to reactive oxygen species | CD36, CDK2, DHFR, DNM2, DPEP1, KCNC2, PRDX1, SOD2, TRAF2, AKR1C3, RGN |
773 | GO:0045137 | 0.00 | 2.56 | 28.60 | 53 | 121 | development of primary sexual characteristics | NR0B1, ANG, ATRX, BAX, BCL2L1, BMP4, BOK, BRCA2, CAPN5, CCNE1, CHAT, COL9A3, CTNNA1, FANCF, FANCG, FGF7, FSHB, CENPI, FSHR, GATA4, GATA6, GDF9, ICAM1, IDH1, ING2, INHA, KDR, KIT, KITLG, PGR, PRKACG, PTPRN, RARA, RRM1, SALL1, SOX9, SRD5A1, SRY, STAT5B, TSPY1, UBB, UBE3A, NRIP1, FZD4, AKR1C3, ADAM15, EIF2B2, EIF2S2, SLIT2, REC8, BCL2L11, AKAP9, IRX5 |
774 | GO:0090263 | 0.00 | 2.55 | 19.38 | 36 | 82 | positive regulation of canonical Wnt signaling pathway | XIAP, ARNTL, COL1A1, CSNK1D, DAPK3, DLX5, EDA, FGFR3, FZD2, RBPJ, ILK, SMAD3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, UBB, WNT1, FZD5, PSMF1, FRAT1, PSME3, PSMD14 |
775 | GO:1903038 | 0.00 | 2.55 | 11.82 | 22 | 50 | negative regulation of leukocyte cell-cell adhesion | ANXA1, ASS1, BMP4, CBLB, CTLA4, IFNA2, IHH, IL2RA, IL10, IDO1, IRF1, PRKAR1A, PTPN6, CCL21, CCL25, XCL1, SFTPD, TNFSF4, SCGB1A1, PDE5A, TNFSF18, SOCS6 |
776 | GO:0002562 | 0.02 | 2.55 | 5.91 | 11 | 25 | somatic diversification of immune receptors via germline recombination within a single locus | CD28, IFNG, IL10, RAG1, RAG2, STAT6, TNFSF4, UNG, RNF8, EXO1, IL27RA |
777 | GO:0042345 | 0.02 | 2.55 | 5.91 | 11 | 25 | regulation of NF-kappaB import into nucleus | BCL3, EDA, IL10, IL12B, IL18, PRDX1, PPM1B, PRKCQ, TRIP6, TNFSF14, LITAF |
778 | GO:0042993 | 0.02 | 2.55 | 5.91 | 11 | 25 | positive regulation of transcription factor import into nucleus | CDH1, EDA, HCLS1, IL12B, IL18, SMAD3, PRKCQ, SLC9A1, TRIP6, TNFSF14, AKAP6 |
779 | GO:0043330 | 0.02 | 2.55 | 5.91 | 11 | 25 | response to exogenous dsRNA | DDX1, IFIT1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, KCNJ8, RIPK2, DDX21 |
780 | GO:0097061 | 0.02 | 2.55 | 5.91 | 11 | 25 | dendritic spine organization | ABL2, ARF1, CTNND2, EFNA1, CTTN, EPHB1, EPHB2, EPHB3, CAPRIN1, PTEN, PICK1 |
781 | GO:1903578 | 0.02 | 2.55 | 5.91 | 11 | 25 | regulation of ATP metabolic process | ARNT, TSPO, IGF1, INS, P2RX7, PGAM1, PRKAA1, PRKAG1, SNCA, STAT3, OGT |
782 | GO:0000165 | 0.01 | 2.54 | 8.00 | 15 | 35 | MAPK cascade | CHUK, CREB1, ELK1, IL18, SMAD1, PPP2R5D, RBM4, RPS6KA1, SKP1, NR2C2, SCG2, CUL1, RB1CC1, SH2D3C, SH2D3A |
783 | GO:0003012 | 0.01 | 2.54 | 6.96 | 13 | 30 | muscle system process | AGTR2, CYBA, GATA6, GTF2I, IGF1, TBCE, TRPC3, AKAP1, SORBS2, CTDP1, KLF4, AKAP6, KDM4A |
784 | GO:0002376 | 0.02 | 2.54 | 5.77 | 11 | 27 | immune system process | ADSS, CD151, EPHB1, HP, HPRT1, IMPDH1, IMPDH2, INPPL1, PTMS, TRPV1, ZNF3 |
785 | GO:0009636 | 0.00 | 2.54 | 31.43 | 58 | 133 | response to toxic substance | ALAD, ALB, ARG1, ASS1, BAX, CASP9, CAT, CCNB1, CD36, CDH1, CDK2, CDK4, CDKN1A, CHUK, CNP, CPOX, CPS1, CYP2F1, DHFR, DNMT1, DNMT3B, ERCC6, ETS1, GPX1, GPX2, GRIA4, GSTZ1, GUCY2C, HBA2, HMBS, HP, HSPA9, KCNC2, MGMT, CIITA, PRDX1, PENK, PPP2CB, PTGS1, RAD51, RPS6KB1, S100A9, SCN8A, SEPW1, SHC1, SLC9A1, SOD2, SRD5A1, SRF, TYMS, UROS, XPA, OGT, RGN, SLC22A8, GSTO1, HDAC6, DHRS2 |
786 | GO:0002223 | 0.00 | 2.54 | 18.91 | 35 | 80 | stimulatory C-type lectin receptor signaling pathway | CALM3, CHUK, EP300, FYN, ICAM2, ITPR1, PRKACB, PRKACG, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, RAF1, SKP1, UBB, UBE2D2, CUL1, IKBKG, UBA3, PSMF1, PSME3, PSMD14 |
787 | GO:0008543 | 0.00 | 2.54 | 44.67 | 82 | 189 | fibroblast growth factor receptor signaling pathway | ANGPT1, ARAF, BAD, CALM3, CAMK2A, CASP9, RUNX2, CBL, CD28, CD86, CDKN1A, CHUK, CREB1, CSF2RB, CTGF, DUSP5, FGF3, FGF4, FGF7, FGFR3, FYN, GRB2, GRIN2A, NRG1, NR4A1, IL2RA, ITPR1, KIT, MARK3, KITLG, FOXO4, OTX2, PPP2CB, PPP2R1A, PPP5C, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, PTPRA, RAF1, RASA2, RPS6KB2, SHC1, UBB, VAV1, SHOC2, FGF23, CUL3, PEA15, PSMF1, NRG2, RAPGEF2, RBX1, FGFBP1, AKAP9, RASA4, PSME3, PSMD14, SPRY1 |
788 | GO:0030038 | 0.00 | 2.53 | 11.34 | 21 | 48 | contractile actin filament bundle assembly | ARHGAP6, BBS4, CTGF, S1PR1, LPAR1, PTK2B, LIMK1, SMAD3, PFN2, PRKCQ, RAC1, SDC4, SLC9A1, SRF, TSC1, WNT11, ARHGEF5, CUL3, ITGB1BP1, BAG4, WASF2 |
789 | GO:0032602 | 0.01 | 2.52 | 7.56 | 14 | 32 | chemokine production | ALOX15B, CSF1R, FFAR3, IFNG, IL10, IL18, P2RY2, S100A8, S100A9, ADAM17, TNFSF4, RIPK2, IL1RL1, KLF4 |
790 | GO:1901701 | 0.00 | 2.52 | 76.37 | 139 | 332 | cellular response to oxygen-containing compound | ANGPT1, ANXA5, APRT, ARAF, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, BAD, CALM3, CAMK2A, AKR1C4, CSF2RB, CSH1, CYP11B1, DRD5, DUSP5, LPAR1, EFNA5, EIF4E, EPHA5, FBN1, FGF3, FGF4, FGF7, FGFR3, FYN, GATA4, GCG, GCGR, GH2, GHRHR, GHSR, GNAI1, GNG3, GNG10, GNRHR, GRB2, GRIN2A, NRG1, HMGCR, NR4A1, FOXA2, IGF1R, IGF2, IL1R1, IL2RA, INS, KCNJ11, KIT, MARK3, KITLG, FOXO4, YBX1, OXCT1, P2RX4, P2RY11, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCI, PRKCQ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTK2, PTPN6, PTPRA, PTPRE, PTPRN, PTPRN2, RAF1, RANGAP1, RASA2, RHEB, RPS6, RPS6KB1, RXRA, RYR2, SRSF5, SHC1, SHMT1, SIPA1, SLC2A4, SLC2A5, SLC9A1, SMARCA4, SNCA, SRF, STAT3, STAT5B, ADAM17, KLF10, HSP90B1, TSC1, UBB, USF1, TRPV1, WNT1, ZNF16, CUL3, PIK3R3, PEA15, SOCS3, ATP6V0D1, IL1RL1, ARHGEF2, HMGN3, GLP2R, SLIT2, NRXN1, PSMF1, NRG2, ATP6V1G1, BCAR1, C2CD5, RBX1, RASA4, PSME3, PSMD14 |
791 | GO:0051402 | 0.03 | 2.51 | 5.40 | 10 | 23 | neuron apoptotic process | APAF1, APP, BOK, GAPDH, GPX1, GRID2, RB1, SCN2A, TP63, AATK |
792 | GO:0000278 | 0.00 | 2.51 | 12.39 | 23 | 54 | mitotic cell cycle | FEN1, CENPI, RAB1A, RANGAP1, RBL2, RFC3, RFC4, RFC5, RPS27, RRM1, SET, XRCC2, HIST1H4I, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, BLZF1, USO1, UBA3, USP3 |
793 | GO:0015844 | 0.00 | 2.51 | 9.22 | 17 | 39 | monoamine transport | ABAT, AGTR2, CHRNB2, CNR1, CRH, DRD3, FFAR3, OXTR, P2RX1, PCP4, PTGS1, RAB3B, SLC22A1, SLC22A3, SLC22A2, SNCA, PICK1 |
794 | GO:0030808 | 0.00 | 2.51 | 16.31 | 30 | 69 | regulation of nucleotide biosynthetic process | ABCA1, AVPR2, CALM3, CRH, DRD3, DRD5, LPAR1, EDNRA, PTK2B, FSHR, GALR1, GCG, GHRHR, GNAS, GUCA1A, GUCA2A, GUCA2B, NTRK2, P2RY11, PALM, RAF1, RCVRN, STAT3, VIP, VIPR2, WFS1, AKAP6, GABBR2, AKAP12, GUCA1C |
795 | GO:0009416 | 0.00 | 2.51 | 35.49 | 65 | 151 | response to light stimulus | ABCA4, ABL2, ADRA1B, APP, ATP1A2, ATP1A3, BCL3, OPN1SW, BRCA2, CACNB4, CAT, AKR1C4, CHRM1, CHRNB2, CIRBP, CLU, CLPS, CREB1, CTNS, DBH, DNM2, DRD3, DUSP1, ELK1, ERCC3, ERCC6, FEN1, GPC4, OPN1MW, GPC3, GNAQ, GNAT2, GNGT2, GPX1, GRIN2A, HMGN1, HMGCR, HRH1, IL12B, ITGB1, JUND, KCNC2, KIT, NTRK2, SERPINB13, PRKAA1, RBM4, RBP1, RBP2, OPN1LW, RGR, SDC4, SGK1, TRPC3, TULP1, TYR, USF1, XPA, COPS3, AKR1C3, UNC119, USP2, CLOCK, SDC3, NR2E3 |
796 | GO:0050770 | 0.03 | 2.51 | 5.41 | 10 | 23 | regulation of axonogenesis | CACNA1A, CHN1, DCC, EFNA1, EPHB3, GDI1, PTEN, PTK2, CNTN2, ARHGEF1 |
797 | GO:1903305 | 0.03 | 2.50 | 5.42 | 10 | 23 | regulation of regulated secretory pathway | BCR, FGR, IL13, IL13RA2, PTAFR, RAB27A, RAC2, STXBP2, VAMP8, GAB2 |
798 | GO:0007229 | 0.00 | 2.50 | 12.51 | 23 | 53 | integrin-mediated signaling pathway | ADAM10, DST, CTGF, PTK2B, FGR, FUT8, ILK, ITGA1, ITGA4, ITGA5, ITGA9, ITGAD, ITGAM, ITGAV, ITGB1, PTK2, TYROBP, VAV1, MADCAM1, CUL3, ADAM15, BCAR1, GAB2 |
799 | GO:0031670 | 0.03 | 2.50 | 5.43 | 10 | 23 | cellular response to nutrient | ATP2B1, BGLAP, CCNE1, COL1A1, ITGB1, PENK, PIM1, PTN, FGF23, NR1H4 |
800 | GO:0002437 | 0.03 | 2.50 | 5.43 | 10 | 23 | inflammatory response to antigenic stimulus | AHCY, C3, CD6, CD28, CNR1, ICAM1, RBPJ, IL1A, IL1RN, IL2RA |
801 | GO:0009605 | 0.00 | 2.49 | 107.52 | 194 | 489 | response to external stimulus | ABL2, ACACB, ACADS, ACTB, AHCY, ALB, ALDH1A3, ANGPT1, APAF1, ARAF, ASCL1, ASGR1, ATF4, ATP2B1, BCHE, BRCA2, CACNA1A, CAMK2A, CAT, CCNE1, CD3E, CD63, CD72, CDKN1A, CHAT, CHN1, CCR3, CCR8, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CRY2, CSF1R, CSF2RB, CSNK2A1, DAD1, DCC, DLG3, DLX5, DNM1, DNMT3B, DPYSL3, DUSP5, TYMP, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EGR3, EPHA2, EPHA5, EPHA8, EPHB2, EPHB3, ETV4, FGF3, FGFR3, FLT1, FPR1, FPR3, G6PC, GCGR, GFRA1, GLRA1, XCR1, GRB2, GRIN2A, HGF, NRG1, HLCS, HMBS, NR4A1, HRH1, HTR2C, INHA, ITGA1, ITGA5, ITGA9, ITGAV, KIF5A, LIMK1, LIPC, MARK3, KITLG, MGMT, NRCAM, NTN3, OTX2, OXCT1, PCK1, CHMP1A, PIM1, PPP5C, PRKAA1, PSPN, PSMA1, PSMA3, PSMA4, PSMA5, PSMB1, PSMB2, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTK2, PTN, PTPRA, PTPRJ, RALA, RASA2, RBM4, RHAG, RHCE, RHD, RNASE2, RPL24, RPS6KA1, RXRA, RYK, SAA4, SATB1, SCN5A, CCL25, SHC1, SIPA1, SLC34A1, SLC22A3, SORD, SOS2, SRD5A1, SRF, STC1, SUOX, CNTN2, KLF10, TRPC1, TRPC4, TRPC5, TYMS, TYR, TYROBP, UBB, UPP1, VAV1, WNT11, ARHGEF5, FGF23, SOX14, CUL3, CNTNAP1, HAT1, KLF7, UNC5C, NUMB, PEA15, NRP2, ARHGEF7, KYNU, AP3D1, RPS6KA4, USP2, NRXN3, LIPG, EIF2AK3, PICK1, PSMF1, NRG2, BCAR1, RAPGEF2, ATG13, ARHGEF11, RBX1, RANBP9, ARPC5, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, PSME3, PSMD14 |
802 | GO:0034142 | 0.00 | 2.49 | 12.53 | 23 | 53 | toll-like receptor 4 signaling pathway | BIRC3, BTK, CD36, CHUK, CREB1, ELK1, IRAK1, IRAK2, ITGAM, JUN, LTF, PPP2R5D, PRKCE, RPS6KA1, SKP1, UBB, UBE2D2, CUL1, IKBKG, RIPK1, RIPK2, TRIL, NR1H4 |
803 | GO:0043525 | 0.03 | 2.49 | 5.44 | 10 | 23 | positive regulation of neuron apoptotic process | ASCL1, ATF4, BAX, CASP9, FGFR3, ITGA1, JUN, MAP3K11, SRPK2, BCL2L11 |
804 | GO:0071277 | 0.03 | 2.49 | 5.44 | 10 | 23 | cellular response to calcium ion | CRHBP, DPEP1, GPLD1, GUCA1A, JUN, JUND, SCN5A, SYT1, AKR1C3, RASA4 |
805 | GO:0098801 | 0.03 | 2.49 | 5.44 | 10 | 23 | regulation of renal system process | AGTR1, AGTR2, AVPR2, COMT, CYBA, DRD3, EMP2, F2R, KNG1, STC1 |
806 | GO:1901532 | 0.03 | 2.49 | 5.44 | 10 | 23 | regulation of hematopoietic progenitor cell differentiation | KDR, SOS2, ZNF16, HIST1H4I, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L |
807 | GO:2000107 | 0.03 | 2.49 | 5.44 | 10 | 23 | negative regulation of leukocyte apoptotic process | AXL, BMP4, TSC22D3, HCLS1, IDO1, KITLG, PRKCQ, RAG1, CCL21, AURKB |
808 | GO:0048011 | 0.00 | 2.49 | 55.77 | 101 | 236 | neurotrophin TRK receptor signaling pathway | AGTR2, ANGPT1, ARAF, ARHGAP4, BAD, CALM3, CAMK2A, CASP9, CD28, CD86, CDKN1A, CHUK, AP2S1, CREB1, CRKL, CSF2RB, DUSP5, ELK1, FGD1, FGF3, FGF4, FGF7, FGFR3, FYN, GRB2, RAPGEF1, GRIN2A, NRG1, NR4A1, IL2RA, IRAK1, ITPR1, KIT, MARK3, KITLG, FOXO4, NTRK2, PCSK5, PPP2R5D, PPP5C, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRKCI, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, PTPRA, RAC1, RAF1, RALA, RASA2, RIT1, RPS6KA1, RPS6KB2, SORT1, SHC1, SOS2, STAT3, ADAM17, UBB, VAV1, FGF23, CUL3, PEA15, RIPK2, ARHGEF7, ARHGEF1, ARHGEF2, PSMF1, NRG2, BCAR1, RAPGEF2, ARHGEF11, RBX1, BCL2L11, AKAP9, RASA4, PSME3, PSMD14, SPRY1 |
809 | GO:0071326 | 0.00 | 2.49 | 15.83 | 29 | 67 | cellular response to monosaccharide stimulus | BAD, CRH, CYBA, EFNA5, EPHA5, GATA4, GCG, GHRHR, GPLD1, HMGCR, FOXA2, ICAM1, IGF1, IGF1R, IL1R1, KCNJ11, OXCT1, SERPINF1, PRKCE, PTPRN, PTPRN2, RAF1, SLC2A5, SMARCA4, SRF, OGT, HMGN3, NRXN1, NR1H4 |
810 | GO:0031099 | 0.00 | 2.49 | 10.35 | 19 | 44 | regeneration | ANXA1, TSPO, CCNB1, CTNNA1, DHFR, GFAP, GPX1, IGF1, ISL1, JUN, NTRK3, PRKCQ, PTEN, RXRA, TNR, FZD7, ADAM15, KLF4, CHST3 |
811 | GO:0046425 | 0.00 | 2.48 | 17.49 | 32 | 74 | regulation of JAK-STAT cascade | CHAD, CSF1R, CTF1, DCN, F2R, PTK2B, FGFR3, FLT3, FYN, GP1BA, HCLS1, HPX, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IL10, IL12B, IL13, IL18, ISL1, KIT, PPP2R1A, TNFRSF1A, TNFRSF18, TNFSF18, SOCS3, SOCS6 |
812 | GO:0051351 | 0.00 | 2.48 | 17.49 | 32 | 74 | positive regulation of ligase activity | BMI1, CCNB1, CDC20, CDC27, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, SKP1, UBB, UBE2L3, CUL1, CDC14B, CDC23, CDC16, PSMF1, PSME3, PSMD14 |
813 | GO:0030003 | 0.00 | 2.48 | 67.12 | 121 | 284 | cellular cation homeostasis | ABCB7, ABL1, ABL2, ADRA1B, AGTR1, AGTR2, ALAS2, ANXA6, APLP2, APP, ARF1, ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP4A, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, AVPR1B, BAX, BMP4, CACNA1A, CACNB4, CALM3, CASQ1, CASQ2, CAV3, CD4, CD36, CD52, CLCN3, CLN5, CCR3, CCR8, CYBA, DIAPH1, DRD3, DRD5, S1PR1, LPAR1, EDNRA, F2, F2R, PTK2B, FTL, GALR1, GNA15, GNAT2, GNG3, XCR1, GRINA, GRM1, GTF2I, HEXB, HPX, HRC, HTR2C, IL13, ITGB1, ITPR1, KCNJ2, KCNK3, KISS1, KNG1, LTF, NUBP1, NTSR1, OXTR, P2RX3, P2RX4, P2RX5, P2RX7, P2RY2, P2RY4, PLN, PRKCE, PRKD1, PTPN6, PYGM, RYR1, RYR2, S100A8, S100A9, SCO1, CCL21, XCL1, SGK1, SLC8A3, SLC9A1, SNCA, STC1, TNNI3, TPT1, HSP90B1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, TRPV1, WFS1, SLC30A2, S1PR4, INPP4B, AP3D1, RGN, ATP6V0D1, VAPB, GSTO1, AKAP6, ATG5, ATP6V1G1, ABCB6, SGK2 |
814 | GO:0031397 | 0.00 | 2.48 | 24.11 | 44 | 102 | negative regulation of protein ubiquitination | ABL1, BUB1B, TSPO, CCNB1, CDC20, CDC27, CENPF, DUSP1, FYN, LIMK1, SMAD7, PRKCE, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, RPS3, TTK, UBB, USP4, WNT1, ZNF207, OGT, CDC23, CDC16, ZW10, ATG5, PSMF1, BAG5, PSME3, PSMD14 |
815 | GO:0050776 | 0.00 | 2.48 | 39.41 | 72 | 171 | regulation of immune response | ADAR, ANGPT1, ARAF, BAD, BCR, BST2, CAMK2A, CASP9, CD8A, CD37, CDH1, CDKN1A, COL1A1, CSF2RB, CTSH, CXADR, DUSP5, FCGRT, FGF3, FGF4, FGF7, FGFR3, GPX1, GRIN2A, NRG1, NR4A1, ICAM1, ICAM4, IFNA5, IFNA13, IFNA17, IFNA21, IFNGR1, IGF2, IL2RA, IL13RA2, INS, ITGA4, ITGB1, KIT, SMAD3, MARK3, KITLG, FOXO4, CD200, SERPINB9, PPP5C, PTPRA, RAC2, RASA2, RPS6KB2, SERPINB4, SELL, SFTPD, SHC1, STAT2, STXBP2, TYROBP, SUMO1, NR1H2, FGF23, MADCAM1, CUL3, PEA15, SOCS3, ATG5, NRG2, RAPGEF2, RBX1, AKAP9, RASA4, CD96 |
816 | GO:0061178 | 0.01 | 2.48 | 7.09 | 13 | 30 | regulation of insulin secretion involved in cellular response to glucose stimulus | BAD, CRH, EFNA5, EPHA5, GCG, GPLD1, HMGCR, FOXA2, OXCT1, PRKCE, HMGN3, NRXN1, NR1H4 |
817 | GO:1903146 | 0.01 | 2.48 | 7.09 | 13 | 30 | regulation of mitophagy | ACTL6A, BNIP3L, TSPO, CSNK2A2, CTSK, CTTN, KAT2A, SREBF1, ZBTB17, FZD5, RUVBL1, ATG5, HDAC6 |
818 | GO:0033138 | 0.01 | 2.48 | 8.73 | 16 | 37 | positive regulation of peptidyl-serine phosphorylation | ANGPT1, ARAF, CD44, GCG, HCLS1, NTRK2, NTRK3, PFN2, PRKD1, RAF1, SNCA, BCAR3, RIPK2, LATS1, BAG4, AKAP9 |
819 | GO:0070301 | 0.01 | 2.47 | 8.74 | 16 | 37 | cellular response to hydrogen peroxide | ABL1, ANXA1, ARG1, ETS1, F3, HGF, PPP5C, PRKAA1, PSAP, PYCR1, RPS3, STAT6, KLF4, HDAC6, IL18BP, TRAP1 |
820 | GO:1901652 | 0.05 | 2.47 | 4.33 | 8 | 19 | response to peptide | AVPR1B, AVPR2, IRF5, KLF10, RIPK2, IL1RL1, ARHGEF2, KLF4 |
821 | GO:0042593 | 0.00 | 2.47 | 26.94 | 49 | 114 | glucose homeostasis | ADRA1B, BAD, CAV3, CNR1, CRH, CRY2, CYBA, CYP11B1, DBH, EFNA5, EPHA5, G6PC, GATA4, GCG, GCGR, GHRHR, GPLD1, FFAR1, HMGCR, FOXA2, ICAM1, IGF1, IGF1R, IL1R1, INS, KCNJ11, OXCT1, PCK1, PDK4, SERPINF1, PRCP, PRKAA1, PRKCE, PTPRN, PTPRN2, RAF1, RANBP2, RPS6, SLC2A4, SMARCA4, SRF, STAT3, HNF1A, USF1, WFS1, OGT, HMGN3, NRXN1, NR1H4 |
822 | GO:0042752 | 0.00 | 2.47 | 12.05 | 22 | 51 | regulation of circadian rhythm | ALB, ARNTL, CHRM1, CHRNB2, CREB1, CRH, CRY2, CSNK1D, DRD3, GHRHR, GNAQ, PRKAA1, RBM4, SFPQ, KLF10, TOP2A, UBE3A, SOX14, PER3, USP2, CLOCK, NR1D2 |
823 | GO:0050818 | 0.00 | 2.47 | 12.05 | 22 | 51 | regulation of coagulation | ABAT, ANXA5, APOH, CD36, F2, F2R, F3, F7, FAP, FGA, GP1BA, FOXA2, HRG, KLKB1, KNG1, SERPINE1, PRKCQ, PROC, S100A9, SELP, USF1, VTN |
824 | GO:0097530 | 0.00 | 2.47 | 13.71 | 25 | 58 | granulocyte migration | ANXA1, CXADR, EDNRA, CXCL3, HRH1, IFNG, ITGA1, ITGA9, PDE4B, RAC1, RAC2, S100A7, S100A8, S100A9, S100A12, CCL21, CCL22, CCL25, XCL1, CX3CL1, XCL2, VAV1, SCG2, TNFSF18, SLIT2 |
825 | GO:0071453 | 0.00 | 2.46 | 18.67 | 34 | 79 | cellular response to oxygen levels | ARNT, BACH1, BAD, BNIP3L, CCNB1, CLCA1, DNMT3B, LPAR1, EP300, GATA6, GNGT1, ICAM1, RBPJ, IRAK1, KCND2, KCNK2, KCNK3, PRKAA1, PRKCE, PTEN, PTGIS, PTN, SLC2A4, SLC8A3, SLC9A1, STC1, TRPC1, TSC1, UBB, UBE2D2, CUL2, OGT, PICK1, RBX1 |
826 | GO:0071333 | 0.00 | 2.46 | 15.36 | 28 | 65 | cellular response to glucose stimulus | BAD, CRH, CYBA, EFNA5, EPHA5, GATA4, GCG, GHRHR, GPLD1, HMGCR, FOXA2, ICAM1, IGF1, IGF1R, IL1R1, KCNJ11, OXCT1, SERPINF1, PRKCE, PTPRN, PTPRN2, RAF1, SMARCA4, SRF, OGT, HMGN3, NRXN1, NR1H4 |
827 | GO:0009755 | 0.04 | 2.46 | 4.91 | 9 | 21 | hormone-mediated signaling pathway | ASIP, CRH, CRHBP, FSHR, GCGR, GHSR, PRCP, STAT5B, LATS1 |
828 | GO:0030198 | 0.00 | 2.46 | 29.73 | 54 | 127 | extracellular matrix organization | ACTN1, APLP2, APP, BCL3, BMP4, DST, CD36, CD151, COMP, VCAN, CTGF, FBLN1, FBLN2, EFEMP1, FGA, GFAP, B4GALT1, ICAM1, ICAM2, ICAM4, IHH, ILK, ITGA1, ITGA4, ITGA5, ITGA9, ITGAD, ITGAM, ITGAV, ITGB1, KDR, LAMA4, LTBP2, MATN3, MFAP3, P4HA1, SERPINE1, SERPINB5, PPIB, PTK2, PTPRS, SDC4, SNCA, SPARC, TNR, VTN, MADCAM1, RIPK1, NRXN1, ADAMTS3, ADAMTS2, SDC3, ADAMTSL2, SPOCK2 |
829 | GO:0033157 | 0.04 | 2.45 | 4.93 | 9 | 21 | regulation of intracellular protein transport | AGTR2, BCL3, BNIP3L, CDKN1A, GNAQ, PRDX1, SREBF1, FZD7, RGS20 |
830 | GO:0033273 | 0.02 | 2.45 | 6.59 | 12 | 28 | response to vitamin | ALAD, ASCL1, BCHE, TSPO, CCNE1, COL1A1, F7, HLCS, HMBS, MGMT, SPARC, KYNU |
831 | GO:0042542 | 0.01 | 2.44 | 8.24 | 15 | 35 | response to hydrogen peroxide | BAD, CAT, COL1A1, DUSP1, PTK2B, GJA3, GPX1, HBA2, HP, JUN, KPNA4, OLR1, PPP2CB, SHC1, FOSL1 |
832 | GO:0007270 | 0.04 | 2.44 | 4.94 | 9 | 21 | neuron-neuron synaptic transmission | CHRNB2, CRH, CRHBP, DRD3, DRD5, GLRA1, RAB3B, SNCA, SLC6A5 |
833 | GO:0042310 | 0.02 | 2.44 | 6.60 | 12 | 28 | vasoconstriction | AGTR1, ATP1A2, BMPR2, CHRM1, CHRM3, ACE, DRD5, EDNRA, P2RX1, PRKCQ, CX3CL1, KCNMB2 |
834 | GO:0002819 | 0.00 | 2.44 | 14.89 | 27 | 63 | regulation of adaptive immune response | ANXA1, BTK, C3, CD4, CD28, CLC, FCER2, HPX, IFNA2, IFNG, IL10, IL12B, IRF1, P2RX7, PRKCQ, PTPN6, PVR, XCL1, STAT6, TRAF2, TNFSF4, UNG, FZD5, RIPK2, TNFSF18, IL1RL1, IL27RA |
835 | GO:0071482 | 0.02 | 2.44 | 6.60 | 12 | 28 | cellular response to light stimulus | CALM3, CNGA1, CRY2, GNAT1, GNGT1, GUCA1A, GUCY2F, GUCY2D, PRKCQ, RCVRN, RPGR, GUCA1C |
836 | GO:0051899 | 0.02 | 2.44 | 6.60 | 12 | 28 | membrane depolarization | ABL1, TSPO, CACNB4, CHRNB2, DCN, JUN, KDR, SMAD7, NTSR1, P2RX4, P2RX7, HCN4 |
837 | GO:0051705 | 0.00 | 2.44 | 9.93 | 18 | 42 | multi-organism behavior | APLP2, APP, BBS4, CHRNB2, CRHBP, DBH, DRD3, DRD5, GNAQ, GRID1, HEXB, OXTR, PENK, PEX13, PTEN, NRXN3, NRXN1, NRXN2 |
838 | GO:0043066 | 0.00 | 2.43 | 66.51 | 119 | 286 | negative regulation of apoptotic process | ADAR, ALB, ANXA1, ANXA5, ARAF, ASCL1, BARD1, BCL2A1, BCL3, BLK, BNIP3L, CAT, CBL, CD59, CDKN1A, CLU, COMP, CSF1R, CTH, CTNNA1, CTSH, CX3CR1, DAD1, DFFA, DUSP1, EDNRA, EGR3, CTTN, FGF4, FLT4, GATA6, GCG, GRINA, HSPA9, HSPB1, IFIT3, IGF1R, IHH, IL1A, IL10, ING2, INS, IRAK1, ITGAV, KCNJ1, LTF, SMAD3, SMAD6, YBX1, NTSR1, OPA1, PA2G4, PIM1, PRKAA1, PROC, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, RARA, RARB, RPS3A, RPS6KB1, CX3CL1, SGK1, STIL, SLC9A1, SNAI1, SOX9, SOX10, STAT3, STAT5B, SUPV3L1, TPT1, HSP90B1, UBB, UNG, VDAC2, VIP, WNT1, WNT11, YWHAZ, ZNF16, API5, TP63, PEA15, RIPK2, TNFRSF18, TNFRSF10D, TAX1BP1, TNFSF18, SOCS3, RGN, ARHGEF2, EIF2AK3, ATG5, PSMF1, BAG5, BAG4, RB1CC1, NR1H4, TRAP1, PSME3, DHRS2, PSMD14 |
839 | GO:0045453 | 0.01 | 2.43 | 8.27 | 15 | 35 | bone resorption | ATP6AP1, BGLAP, TPP1, CSF1R, CTSK, S1PR1, PTK2B, FSHB, IAPP, IHH, P2RX7, PDK4, RAC1, RAC2, GPR55 |
840 | GO:1903725 | 0.01 | 2.43 | 8.27 | 15 | 35 | regulation of phospholipid metabolic process | ARF1, EPHA8, PTK2B, FGFR3, FGR, FLT1, FLT3, HTR2C, IDH1, KIT, PTK2, RAC1, CCL21, PIK3R3, KLF4 |
841 | GO:0010463 | 0.04 | 2.43 | 4.96 | 9 | 21 | mesenchymal cell proliferation | BMPR1A, FGF4, FGF7, GPC3, IHH, KDR, SOX9, TP63, CHRD |
842 | GO:0002312 | 0.02 | 2.43 | 6.62 | 12 | 28 | B cell activation involved in immune response | ABL1, BCL3, CD28, PTK2B, IFNG, IL10, STAT6, TNFSF4, UNG, RNF8, EXO1, IL27RA |
843 | GO:0007411 | 0.00 | 2.43 | 73.03 | 130 | 310 | axon guidance | ABL1, ABL2, ACTB, ADAM10, ANGPT1, APP, ARAF, BMPR2, CACNB4, CALM3, CAMK2A, CD72, AP2S1, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2RB, CSNK2A1, CSNK2A2, DCC, DLG3, DLX5, DNM1, DPYSL3, DUSP5, EFNA1, EFNA3, EFNA4, EFNB1, EPHA2, EPHA5, EPHA8, EPHB2, FGF3, FGF4, FGF7, FGFR3, FYN, GFRA1, GRB2, GRIN2A, NRG1, IL2RA, ITGA1, ITGA5, ITGA9, ITGAV, ITGB1, KIF5A, KIT, LIMK1, MARK3, KITLG, NTN3, OTX2, PPP5C, PRKCQ, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTK2, PTPRA, RAC1, RAC2, RAF1, RASA2, RPS6KA1, RYK, SCN5A, SHC1, SOS2, CNTN2, TNR, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, SEMA3B, FGF23, CUL3, CNTNAP1, KLF7, UNC5C, NUMB, PEA15, NRP2, ARHGEF7, RPS6KA4, NRXN3, NRXN1, PSMF1, NRG2, FEZ2, RAPGEF2, SEMA3E, ARHGEF11, RBX1, RANBP9, ARPC5, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, PSME3, PSMD14 |
844 | GO:0035272 | 0.04 | 2.43 | 4.96 | 9 | 21 | exocrine system development | EDA, FGF7, HGF, IGF1, IGF1R, IGF2, SOX9, SOX10, NRP1 |
845 | GO:0046850 | 0.04 | 2.43 | 4.96 | 9 | 21 | regulation of bone remodeling | ATP6AP1, BGLAP, CSF1R, S1PR1, FSHB, IAPP, P2RX7, PDK4, INPP4B |
846 | GO:0048048 | 0.04 | 2.43 | 4.96 | 9 | 21 | embryonic eye morphogenesis | ALDH1A3, FBN1, EFEMP1, IHH, RARB, SIX3, SOX11, SP1, FZD5 |
847 | GO:0050829 | 0.04 | 2.43 | 4.96 | 9 | 21 | defense response to Gram-negative bacterium | APP, BPI, CD4, FCN2, IL12B, SERPINE1, S100A7, SELP, VIP |
848 | GO:0051966 | 0.04 | 2.43 | 4.96 | 9 | 21 | regulation of synaptic transmission, glutamatergic | ATP1A2, CNR1, PTK2B, NTRK2, OXTR, SYT1, TNR, DGKI, NRXN1 |
849 | GO:0055082 | 0.00 | 2.43 | 85.79 | 152 | 363 | cellular chemical homeostasis | ABCB7, ABL1, ABL2, ADRA1B, AGTR1, AGTR2, ALAS2, ANXA6, APLP2, APP, ARF1, ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP4A, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, AVPR1B, BAD, BAX, BMP4, CACNA1A, CACNB4, CALM3, CASQ1, CASQ2, CAV3, CD4, CD36, CD52, CLCN3, CLN5, CCR3, CCR8, CRH, CYBA, DIAPH1, DRD3, DRD5, S1PR1, LPAR1, EDNRA, EFNA5, EPHA5, F2, F2R, PTK2B, FTL, GALR1, GATA4, GCG, GHRHR, GNA15, GNAT2, GNG3, GPLD1, XCR1, GRINA, GRM1, GTF2I, HEXB, HMGCR, FOXA2, HPX, HRC, HTR2C, ICAM1, IGF1, IGF1R, IL1R1, IL13, ITGB1, ITPR1, KCNJ2, KCNJ11, KCNK3, KISS1, KNG1, LTF, NUBP1, NTSR1, OXCT1, OXTR, P2RX3, P2RX4, P2RX5, P2RX7, P2RY2, P2RY4, SERPINF1, PLN, PRKCE, PRKD1, PTPN6, PTPRN, PTPRN2, PYGM, RAF1, RANBP2, RHAG, RYR1, RYR2, S100A8, S100A9, SCO1, CCL21, XCL1, SGK1, SLC4A1, SLC8A3, SLC9A1, SMARCA4, SNCA, SRF, STC1, TNNI3, TPT1, HSP90B1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, TRPV1, WFS1, SLC30A2, FGF23, OGT, S1PR4, INPP4B, AP3D1, RGN, ATP6V0D1, VAPB, HMGN3, SLC9A3R1, NRXN1, GSTO1, AKAP6, ATG5, ATP6V1G1, NR1H4, ABCB6, SGK2 |
850 | GO:0052548 | 0.00 | 2.43 | 15.46 | 28 | 66 | regulation of endopeptidase activity | APAF1, BAD, BAX, BOK, CASP9, CTGF, CTSH, F2R, F3, HIP1, SMAD3, MGMT, P2RX1, PSMA3, REST, RPS3, S100A8, S100A9, TP63, CRADD, EIF2AK3, KIAA0141, TNFSF15, CASP8AP2, PDCD6, BCL2L11, PSME3, PSMD14 |
851 | GO:0048639 | 0.00 | 2.42 | 12.74 | 23 | 54 | positive regulation of developmental growth | ACACB, BMPR2, C3, CCNB1, EFNA5, GATA4, GATA6, GOLGA4, NRG1, IGF1, RBPJ, ILK, LIMK1, NTRK3, RAG2, RPS6KB1, SRF, SYT1, SYT4, RND2, NRP1, AKAP6, RIMS2 |
852 | GO:0090068 | 0.00 | 2.42 | 21.64 | 39 | 92 | positive regulation of cell cycle process | ATRX, CCNB1, CDK2, CDKN1A, CTGF, FAP, GATA6, OPN1MW, FOXO4, ORC1, PRKCE, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, OPN1LW, SFPQ, TP73, UBB, RNF112, CRADD, AURKB, KIF3B, PSMF1, PSME3, PSMD14 |
853 | GO:0071363 | 0.00 | 2.42 | 29.83 | 54 | 131 | cellular response to growth factor stimulus | ACVR2B, ANGPT2, ARHGAP4, BGLAP, BMP1, BMP3, BMP8B, BYSL, CAT, AP2S1, CLU, CRKL, DLX5, ELK1, FGD1, FLT3, FLT4, GAS1, HSPB1, IRAK1, KCND3, KDR, NTRK3, PAX9, PCSK5, PPP2R5D, PRKCI, PRKD1, PTN, RAC1, RALA, RAP1GAP, RIT1, RPS6KA1, RPS6KB1, RYR2, SOS2, SPARC, SRD5A1, STAT3, STAT5B, TNFRSF1B, RIPK1, RIPK2, NRP2, ARHGEF7, PHOX2B, ARHGEF1, ARHGEF2, KLF4, BAG4, ZFYVE16, ARHGEF11, BCL2L11 |
854 | GO:1903039 | 0.00 | 2.41 | 25.05 | 45 | 106 | positive regulation of leukocyte cell-cell adhesion | ANXA1, BAD, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD28, CD86, CD44, CD59, CTLA4, DPP4, EFNB1, EGR3, FLOT2, FYN, GRB2, IFNG, IGF1, IGF2, IHH, IL2RA, IL12B, IL18, ITGA4, PRKCQ, PTAFR, PTPN6, RAC1, RAG1, RARA, CCL21, XCL1, STAT5B, TRAF2, TNFSF4, VAV1, AP3B1, TNFSF14, TNFSF9, RIPK2, AP3D1, GRAP2 |
855 | GO:0070661 | 0.00 | 2.41 | 36.87 | 66 | 156 | leukocyte proliferation | ABL1, ANXA1, BAX, PRDM1, BMP4, CBLB, CD3E, CD4, CD6, CD28, CD86, CD59, CD151, CDKN1A, CHRNB2, CLC, CLU, CR2, CTLA4, ACE, EFNB1, FLT3, FYN, HPRT1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF2, IHH, IL2RA, IL10, IL12B, IL13, IL18, IMPDH1, IMPDH2, IDO1, IRF1, ITGAD, KIT, LMO1, KITLG, P2RX7, PRKAR1A, PRKCQ, PTPN6, RAC2, RAG2, SATB1, XCL1, SFTPD, SOS2, SOX11, STAT5B, TNFSF4, SCGB1A1, PDE5A, TNFSF14, TNFSF9, RIPK2, TNFSF18 |
856 | GO:0021700 | 0.00 | 2.41 | 32.38 | 58 | 137 | developmental maturation | ABL2, ACVRL1, ANG, APP, ARCN1, ASCL1, RERE, AXL, BRCA2, BTK, CACNA1A, RUNX2, CCNB1, CD63, CDC20, CDKN1A, CLCN3, CLN5, S1PR1, EPHA8, PTK2B, FGFR3, GHRHR, GNAQ, IGF1, RBPJ, IHH, KDR, LTF, NRCAM, OPA1, PALM, PGR, PPP2R1A, PTEN, RAC1, RAC3, RB1, RFX3, RYR1, CCL21, SIX3, SOX10, SYP, TAL1, CNTN2, TYMS, WNT1, FZD5, PICALM, AP1M1, AP3D1, NRXN3, NRXN1, PICK1, REC8, FEM1B, IRX5 |
857 | GO:0071396 | 0.03 | 2.40 | 5.51 | 10 | 24 | cellular response to lipid | BAD, BGLAP, LPAR1, GNAI1, GPLD1, ITGB1, PENK, PIM1, PTN, FGF23 |
858 | GO:0071407 | 0.00 | 2.40 | 27.81 | 50 | 120 | cellular response to organic cyclic compound | ABCA1, ABL1, ADAR, BAD, BGLAP, BYSL, CASQ2, CCNB1, CDH1, COL1A1, CTNNA1, CYBA, DIAPH1, DNM2, DRD5, FGA, GNAI1, GNAS, GPLD1, HRH1, IFIT1, IL18, ITGB1, KCNJ11, SMAD1, SMAD3, SMAD9, MGMT, P2RX4, P2RX7, P2RY2, P2RY6, P2RY11, PDE4B, PIM1, PTN, RAD51, RPS6KB1, RYR1, RYR2, SHMT1, SLC9A1, SLC34A1, SNCA, STAT3, HSP90B1, TRPV1, FGF23, RGS20, KLF4 |
859 | GO:0030819 | 0.01 | 2.40 | 9.45 | 17 | 40 | positive regulation of cAMP biosynthetic process | ABCA1, AVPR2, CALM3, CRH, DRD5, EDNRA, FSHR, GCG, GHRHR, GNAS, NTRK2, P2RY11, RAF1, VIP, VIPR2, WFS1, AKAP12 |
860 | GO:0006836 | 0.03 | 2.40 | 6.11 | 11 | 26 | neurotransmitter transport | ATP1A2, DRD3, GFAP, KCNJ10, RAB3B, SLC6A6, SLC6A7, SLC22A1, SLC22A3, SLC6A5, SV2B |
861 | GO:0032508 | 0.01 | 2.39 | 7.79 | 14 | 33 | DNA duplex unwinding | ANXA1, ATRX, CHD2, CHD4, DDX1, ERCC3, SUPV3L1, XRCC5, RUVBL1, RECQL5, CHD1L, GINS1, RAD50, G3BP1 |
862 | GO:0000184 | 0.00 | 2.39 | 18.43 | 33 | 78 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | FAU, EIF3E, PPP2R1A, PPP2R2A, UPF1, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, RPL14, RPL23, DHX34, EIF4A3, SMG7, RBM8A |
863 | GO:0060548 | 0.00 | 2.39 | 95.29 | 167 | 407 | negative regulation of cell death | ABL1, ABL2, ADAR, ALB, ANXA1, ANXA5, BIRC3, XIAP, BIRC5, APOH, ARAF, ASCL1, BAD, BARD1, BCL2A1, BCL3, BLK, BMP4, BNIP3L, CAT, CBL, KRIT1, CD44, CD59, CDKN1A, CLU, COMP, CRH, CSF1R, CSNK2A1, CTGF, CTH, CTNNA1, CTSH, CX3CR1, DAD1, DFFA, DPEP1, TSC22D3, DUSP1, EDNRA, EGR3, CTTN, FGA, FGF4, FLT4, GATA6, GCG, GRINA, HCLS1, NRG1, HMGCR, HSPA9, ICAM1, IFIT3, IGF1R, IHH, IL1A, IL10, IDO1, ING2, IRAK1, ITGA5, ITGAV, ITGB1, KCNJ1, KDR, KIT, LTF, SMAD3, SMAD6, KITLG, MGMT, YBX1, NTRK3, NTSR1, OPA1, PA2G4, SERPINE1, PDK4, SERPINB9, SERPINB13, PIM1, PRKAA1, PRKD1, PRKCQ, PROC, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, RAF1, RAG1, RARA, RARB, RPS3A, RPS6KA1, RPS6KB1, CCL21, CX3CL1, SGK1, STIL, SLC9A1, SNAI1, SOX9, SOX10, SOX11, STAT5B, SUPV3L1, TPT1, HSP90B1, UBB, UNG, VDAC2, VIL1, VIP, WNT1, WNT11, YWHAZ, ZNF16, SCG2, OGT, API5, TP63, PEA15, TRADD, RIPK1, TNFSF14, TNFSF10, RIPK2, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, WISP3, TAX1BP1, TNFSF18, SOCS3, RGN, ARHGEF2, AURKB, KLF4, EIF2AK3, ATG5, PSMF1, BAG4, BAG3, RB1CC1, NR1H4, PSME3, DHRS2, PSMD14 |
864 | GO:0043154 | 0.00 | 2.38 | 12.29 | 22 | 52 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | BIRC3, XIAP, BIRC5, CD44, CSNK2A1, DPEP1, GPX1, HGF, SERPINB9, RAF1, RAG1, RPS6KA1, SNCA, TRAF2, VIL1, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, KLF4 |
865 | GO:0006367 | 0.00 | 2.38 | 28.07 | 50 | 119 | transcription initiation from RNA polymerase II promoter | NR0B1, RUNX2, CCNC, CCNT2, CDK8, COX6A1, COX6B1, COX7C, COX8A, CTGF, ERCC3, ESRRG, NR5A2, GPX2, GTF2I, NR4A1, HNF4G, RBPJ, SMAD3, SMAD7, MAZ, PRDX1, SERPINE1, PGR, PRKAA1, PRKAG1, RARA, RARB, RHEB, RXRA, RXRG, SP1, TAF4B, TAF7, TAF10, TBP, NR2F1, NR2C1, NR2C2, TSC1, UBB, NR1H2, YWHAZ, ZNF45, USP9X, TP63, NR1I3, NR1H4, NR1D2, NR2E3 |
866 | GO:0032418 | 0.03 | 2.38 | 6.14 | 11 | 26 | lysosome localization | FGR, IL13, IL13RA2, KIT, RAC2, S100A13, STXBP2, LAT2, VAMP8, GAB2, HDAC6 |
867 | GO:0032652 | 0.03 | 2.38 | 6.14 | 11 | 26 | regulation of interleukin-1 production | ANXA1, CASP5, F2R, GHSR, HSPB1, IFI16, IFNG, IL10, ISL1, SMAD3, P2RX7 |
868 | GO:0033280 | 0.03 | 2.38 | 6.14 | 11 | 26 | response to vitamin D | ATP2B1, BGLAP, CD4, ITGB1, PENK, PIM1, PTN, RXRA, STC1, TYR, FGF23 |
869 | GO:0045980 | 0.03 | 2.38 | 6.14 | 11 | 26 | negative regulation of nucleotide metabolic process | TSPO, CDA, DRD3, LPAR1, EDNRA, GALR1, PALM, SNCA, STAT3, AKAP6, GABBR2 |
870 | GO:0046637 | 0.03 | 2.38 | 6.14 | 11 | 26 | regulation of alpha-beta T cell differentiation | ANXA1, CD86, IFNG, IHH, IL12B, RARA, TNFSF4, AP3B1, RIPK2, AP3D1, TNFSF18 |
871 | GO:0001775 | 0.00 | 2.38 | 42.08 | 75 | 183 | cell activation | ABL1, ABL2, ADAM10, ANXA3, BAX, BCL3, ZFP36L2, BST2, RUNX2, CD7, CD8A, TNFSF8, CD151, CDK6, CLC, CR2, CX3CR1, CXADR, EP300, EPHB1, PTK2B, HHEX, ONECUT1, HPRT1, ICAM1, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, RBPJ, IMPDH1, IMPDH2, INS, ITGA4, ITGAD, ITGB1, JUN, KIT, KRT2, LMO1, SMAD3, P2RX4, P2RX7, PTPRE, RAB27A, RAG2, RPL22, S100A12, S100A13, SATB1, SELPLG, SNCA, SOS2, STXBP2, ADAM17, TPD52, TSC1, TYROBP, TRPV1, LAT2, WNT1, ZNF3, FZD5, FZD7, FZD8, FZD9, TPST2, STX11, RNF8, EXO1, IL27RA, SOX13, RNF41, DHRS2 |
872 | GO:0051270 | 0.00 | 2.38 | 19.50 | 35 | 85 | regulation of cellular component movement | ABL1, ABL2, ANXA1, ANXA5, ATP1A1, ATP1A2, BBS4, CDK6, ACE, ECM1, EFNA1, EPHA2, EMP2, EFEMP1, FGF4, GATA4, B4GALT1, KCNJ2, LAMA3, LAMA4, PDE4B, PLN, PRCP, PRKX, RAF1, RYR2, SCN5A, SDC4, SGK1, STK10, TNNC1, SUMO1, SOX14, UNC5C, SLK |
873 | GO:2000241 | 0.00 | 2.38 | 15.13 | 27 | 64 | regulation of reproductive process | ARHGDIB, BMP4, CDC20, CNR1, DUSP1, GDF9, B4GALT1, GLRA1, GPR3, IGF1, OVGP1, OVOL1, OXTR, P2RY2, SERPINF1, PPP2R1A, PRKACB, PRKAR1A, PTAFR, RXRA, SNAI1, SOX9, SPINK1, SRY, VIP, TPST2, PDE5A |
874 | GO:0009952 | 0.00 | 2.38 | 13.43 | 24 | 57 | anterior/posterior pattern specification | ACVR2B, BMP4, BMPR2, CRKL, EMX2, EN1, GATA4, GPC3, HHEX, HOXC10, HOXC11, HOXD8, HOXD9, HOXD10, OTX1, PCSK5, SIX3, SRF, NR2F2, TULP3, WNT1, YY1, FZD5, ATP6AP2 |
875 | GO:0042129 | 0.00 | 2.37 | 13.44 | 24 | 57 | regulation of T cell proliferation | ANXA1, CD3E, CD4, CD6, CD28, CD86, CD59, CLC, EFNB1, IFNG, IGF1, IGF2, IL12B, IL18, IRF1, LMO1, PRKCQ, RAC2, SOS2, STAT5B, TNFSF4, TNFSF9, RIPK2, TNFSF18 |
876 | GO:0006305 | 0.00 | 2.37 | 10.63 | 19 | 45 | DNA alkylation | ATRX, DNMT1, DNMT3B, GNAS, MGMT, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, FKBP6, HIST1H3F, PICK1 |
877 | GO:0050795 | 0.00 | 2.37 | 29.31 | 52 | 124 | regulation of behavior | ADAM10, ALB, ANGPT2, BMPR2, CHRNB2, CNR1, CRH, DRD3, S1PR1, LPAR1, EDNRA, F3, F7, PTK2B, FGF4, GHRHR, CXCL3, HRG, HSPB1, INS, KDR, SMAD3, NTRK3, SERPINE1, PENK, PF4V1, PRKD1, RAC1, RAC2, S100A7, CCL21, CXCL6, CXCL5, XCL1, CX3CL1, SEMA3F, STAT3, ADAM17, TACR3, NR2C2, VEGFB, SCG2, SEMA3B, TNFSF14, NRP1, PER3, TNFSF18, USP14, SLIT2, NRXN1, CXCL14, SEMA3E |
878 | GO:0007613 | 0.00 | 2.36 | 16.31 | 29 | 69 | memory | ATP1A3, CHAT, CHRNB2, CNR1, COMT, CREB1, CTNS, CX3CR1, DBH, FEN1, GRIA1, GRIN2A, HRH1, IGF1, IGF2, ITGA5, KCNK2, NTF4, NTRK2, OXTR, SERPINF1, PTEN, PTGS1, RPS6KB1, SGK1, SLC8A3, SRF, RIN1, RCAN2 |
879 | GO:0072358 | 0.00 | 2.36 | 56.09 | 99 | 242 | cardiovascular system development | ACVRL1, ANG, ANGPT1, ANGPT2, ANXA3, APOH, KLK3, ADGRB2, BAX, BMPR2, KLF5, C3, KRIT1, CDX2, CCR3, COL1A1, COL4A3, COL15A1, CSPG4, CTGF, CTH, CTSH, CX3CR1, DCN, DHCR7, TYMP, ECM1, EGR3, EPHA2, EMP2, EPHB1, EPHB2, EPHB3, ETS1, F3, PTK2B, FAP, FLT1, FLT4, B4GALT1, GJA4, GPLD1, GPX1, RAPGEF1, GTF2I, HGF, NR4A1, HPGD, HRG, HSPB1, IGF1, IL1A, IL18, ITGA5, ITGAV, KCNJ1, KCNQ1, KDR, LLGL2, MEOX2, FOXO4, NRCAM, NTRK2, SERPINE1, SERPINF1, PRCP, PRKD1, PRKX, PTGIS, S100A7, CX3CL1, SHB, SMARCA2, SP100, SRPK2, TAL1, NR2F2, VEZF1, FZD5, SCG2, FOSL1, FZD4, FZD8, SERPINB7, NRP2, SOCS3, ITGB1BP1, KLF4, SLIT2, NRXN3, NRXN1, EIF2AK3, SLC4A7, RAPGEF2, SEMA3E, CUL7, SLC12A6, PDCD6, WASF2 |
880 | GO:0002708 | 0.01 | 2.36 | 8.98 | 16 | 38 | positive regulation of lymphocyte mediated immunity | C3, CD28, FCER2, HPX, IFNG, IL12B, P2RX7, PVR, XCL1, STAT5B, STAT6, TRAF2, TNFSF4, UNG, VAV1, FZD5 |
881 | GO:0045582 | 0.01 | 2.36 | 8.98 | 16 | 38 | positive regulation of T cell differentiation | ANXA1, BAD, CD86, EGR3, IFNG, IHH, IL2RA, IL12B, RAG1, RARA, STAT5B, TNFSF4, AP3B1, TNFSF9, RIPK2, AP3D1 |
882 | GO:1901019 | 0.01 | 2.36 | 8.98 | 16 | 38 | regulation of calcium ion transmembrane transporter activity | ATP1A2, BMP4, CACNB4, CALM3, CASQ2, CAV3, HRC, PDE4B, PLN, RYR2, S100A1, SLC9A1, SUMO1, RGN, GSTO1, AKAP6 |
883 | GO:0030336 | 0.00 | 2.36 | 24.81 | 44 | 105 | negative regulation of cell migration | ACVRL1, AGTR2, ALOX15B, ANGPT2, APOH, ARHGAP4, ARHGDIB, BCR, BST2, KRIT1, CD63, CX3CR1, DCN, DPEP1, DPYSL3, NRG1, HRG, IGFBP3, ILK, SMAD7, SERPINE1, SERPINF1, PFN2, PTEN, PTN, PTPRJ, PTPRR, RAP2A, RAP2B, CCL21, CCL25, SP100, SRF, STAT3, STC1, NR2F2, WNT11, CHRD, ADAM15, ITGB1BP1, KLF4, SLIT2, SLC9A3R1, RNF41 |
884 | GO:0055065 | 0.00 | 2.34 | 63.42 | 111 | 270 | metal ion homeostasis | ABCB7, ABL1, ABL2, ADRA1B, ALAS2, ANXA6, XIAP, APLP2, APP, ARF1, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, AVPR1B, BAX, BMP4, CACNA1A, CACNB4, CALM3, CASQ1, CASQ2, CAV3, CD4, CD36, CD52, CCR3, CCR8, CYBA, DIAPH1, DRD5, S1PR1, LPAR1, EDNRA, F2, F2R, PTK2B, FTL, GALR1, GNA15, GNAT2, GNG3, XCR1, GRINA, GRM1, GTF2I, HEXB, HPX, HRC, HTR2C, IL13, ITGB1, ITPR1, KCNA1, KCNK3, KDR, KISS1, LTF, NUBP1, NTSR1, OXTR, P2RX3, P2RX4, P2RX5, P2RX7, P2RY2, P2RY4, PLN, PRKCE, PRKD1, PTPN6, PYGM, RHAG, RYR1, RYR2, S100A8, S100A9, SCO1, CCL21, XCL1, SLC8A3, SNCA, STC1, TNNI3, TPT1, HSP90B1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, TRPV1, WFS1, SLC30A2, PICALM, S1PR4, INPP4B, AP3D1, RGN, ATP6V0D1, VAPB, GSTO1, AKAP6, ATG5, ATP6V1G1, ABCB6 |
885 | GO:0034112 | 0.00 | 2.34 | 24.34 | 43 | 103 | positive regulation of homotypic cell-cell adhesion | ANXA1, BAD, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD28, CD86, CD44, CD59, CTLA4, DPP4, EFNB1, EGR3, FLOT2, FYN, GRB2, IFNG, IGF1, IGF2, IHH, IL2RA, IL12B, IL18, PRKCQ, PTPN6, RAC1, RAG1, RARA, CCL21, XCL1, STAT5B, TRAF2, TNFSF4, VAV1, AP3B1, TNFSF14, TNFSF9, RIPK2, AP3D1, GRAP2 |
886 | GO:0002791 | 0.00 | 2.34 | 31.20 | 55 | 132 | regulation of peptide secretion | ABAT, ANXA5, ARL2, ARNTL, BAD, BLK, CACNA1A, CHRM3, CNR1, CRH, CRHBP, EFNA5, EPHA5, FGA, GCG, GHRHR, GHSR, GLUD1, GNAS, GPLD1, FFAR1, FFAR3, HMGCR, FOXA2, HTR2C, IFNG, INS, ISL1, ITPR1, KCNC2, KCNJ11, KCNS3, KISS1, OXCT1, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, REST, RFX3, S100A8, S100A9, SNAP25, SREBF1, SYT5, TRPM2, ARHGEF7, SYT7, HMGN3, NRXN1, CLOCK, NR1H4 |
887 | GO:0021885 | 0.02 | 2.34 | 7.33 | 13 | 31 | forebrain cell migration | AXL, CX3CR1, EMX2, NRG1, OGDH, PEX13, RAC1, SRF, CNTN2, TNR, TYRO3, NRP1, SLIT2 |
888 | GO:0034724 | 0.02 | 2.34 | 7.33 | 13 | 31 | DNA replication-independent nucleosome organization | ATRX, CENPA, CENPI, HIST1H4I, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, HAT1, RUVBL1 |
889 | GO:0021510 | 0.00 | 2.34 | 13.00 | 23 | 55 | spinal cord development | ACTL6A, PHOX2A, ASCL1, CACNA1A, DCC, EVX1, HOXC10, HOXD10, ISL1, PAX3, PTN, PTPRS, SOX11, SRD5A1, TAL1, TULP3, WNT1, ZIC1, CHRD, EED, SLIT2, BAG3, OLIG2 |
890 | GO:0071706 | 0.00 | 2.34 | 13.00 | 23 | 55 | tumor necrosis factor superfamily cytokine production | ANGPT1, AXL, BCL3, BPI, TSPO, CD86, TNFRSF8, CD36, CLU, CYBA, GHSR, HSPB1, IFNG, IL10, IL12B, ISL1, LTF, PTAFR, RARA, RIPK1, RIPK2, ARHGEF2, NR1H4 |
891 | GO:0001889 | 0.00 | 2.33 | 16.99 | 30 | 72 | liver development | AK2, ARG1, ASS1, CCNE1, FGA, GATA6, HGF, HMGCS2, ONECUT1, IFNG, JARID2, JUN, KLKB1, LIPC, SMAD3, PHF2, PTN, QDPR, RARA, RPS6KA1, RXRA, SRSF5, SOX9, SP1, SRD5A1, STAT5B, CUL3, RGN, ONECUT2, RB1CC1 |
892 | GO:0010811 | 0.01 | 2.33 | 8.47 | 15 | 36 | positive regulation of cell-substrate adhesion | ARL2, DNM2, FBLN1, FBLN2, FGA, ITGA5, ITGB1, PRKCE, PTN, RAC3, RSU1, VTN, ARHGEF7, SPOCK2, ARPC2 |
893 | GO:0071222 | 0.00 | 2.33 | 19.85 | 35 | 84 | cellular response to lipopolysaccharide | ABCA1, ABL1, ARG1, ASS1, AXL, PRDM1, BYSL, TSPO, CD6, CD86, CD36, ENTPD2, CEBPE, CX3CR1, HMGCS2, ICAM1, IFNG, IL10, IL12B, IL18, IRAK1, IRAK2, LTF, P2RY2, SERPINE1, PDE4B, PRKCE, PTAFR, RARA, UPF1, TNFRSF1B, TNFSF4, OGT, RIPK2, LITAF |
894 | GO:0034329 | 0.00 | 2.33 | 23.27 | 41 | 99 | cell junction assembly | ACTB, ACTN1, ANG, ARL2, DST, CD9, CD151, CDH1, CDH6, CDH7, CDH8, CDH9, CDH10, CDH12, CDH15, CLDN3, CTNNA1, CTTN, PTK2B, GJA4, GJB1, ILK, ITGA5, ITGB1, KRT5, LAMA3, LIM2, SMAD7, PRKCI, PVR, RSU1, FSCN1, SRF, STRN, TBCD, TRIP6, WNT11, CNTNAP1, ARHGEF7, CLDN12, CLDN1 |
895 | GO:0032680 | 0.04 | 2.32 | 5.66 | 10 | 24 | regulation of tumor necrosis factor production | ANGPT1, AXL, BCL3, BPI, TSPO, GHSR, IL10, LTF, RARA, NR1H4 |
896 | GO:0051272 | 0.00 | 2.32 | 56.25 | 98 | 238 | positive regulation of cellular component movement | ADAM10, ANGPT1, ANXA3, BMP4, BMPR2, COL1A1, CSF1R, CTSH, DAPK3, DIAPH1, S1PR1, LPAR1, EDNRA, ETS1, F2R, F3, F7, F10, PTK2B, FBLN1, FGF7, FGR, FLT1, FLT4, FSHB, GPLD1, GRB7, CXCL3, HGF, ONECUT1, HSPB1, ICAM1, IFNG, IGF1, IGF1R, ILK, INS, ITGA4, ITGA5, ITGAV, ITGB1, JUN, KDR, KIT, SMAD3, KITLG, NTRK3, P2RY2, P2RY6, SERPINE1, PF4V1, PRKCE, PRKD1, PTAFR, PTK2, RAC1, RAC2, RPS6KB1, RPS19, S100A7, CCL21, CXCL6, CXCL5, XCL1, CX3CL1, SELE, SELP, SEMA3F, SNAI1, SOX9, SPARC, STAT5B, ADAM17, TRIP6, VEGFB, VIL1, VTN, WNT11, SEMA3B, MADCAM1, IKBKAP, NUMB, TNFSF14, TNFRSF18, NRP2, NRP1, ARHGEF7, TNFSF18, ITGB1BP1, CHST3, ONECUT2, BAG4, CXCL14, BCAR1, RAPGEF2, SEMA3E, HDAC6, PDCD6 |
897 | GO:0070486 | 0.00 | 2.32 | 57.43 | 100 | 243 | leukocyte aggregation | ABL1, ABL2, ANXA1, BAD, BAX, BCL3, BMP4, ZFP36L2, RUNX2, CBLB, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD7, CD8A, CD28, CD86, TNFSF8, CD44, CD59, CD151, CDK6, CLC, CTLA4, CXADR, DPP4, EFNB1, EGR3, FLOT2, FLT3, FYN, GRB2, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF2, IHH, IL2RA, IL10, IL12B, IL18, IDO1, INS, IRF1, ITGAD, KIT, LMO1, SMAD3, P2RX7, PRKAR1A, PRKCQ, PTPN6, RAB27A, RAC1, RAC2, RAG1, RAG2, RARA, RPL22, S100A8, S100A9, SATB1, CCL21, XCL1, SFTPD, SOS2, SRF, STAT5B, STAT6, STK10, ADAM17, TRAF2, TSC1, TNFSF4, SCGB1A1, VAV1, WNT1, FZD5, FZD7, FZD8, AP3B1, PDE5A, STX11, TNFSF14, TNFSF9, RIPK2, AP3D1, TNFSF18, SOCS6, GRAP2, SOX13 |
898 | GO:0031347 | 0.00 | 2.32 | 74.97 | 130 | 319 | regulation of defense response | ADAR, AGTR1, ANXA1, XIAP, BCR, BTK, C3, C7, CALM3, CASP5, CD6, CD86, CD36, CD59, CHUK, CNR1, CREB1, CRH, CTSK, CX3CR1, CYBA, DMBT1, EDNRA, ELK1, EP300, ETS1, FGR, GHSR, FFAR3, GPX1, UBE2K, HPX, ICAM2, IFI16, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNGR1, IGF2, IL1R1, IL10, IL18, IDO1, INS, IRAK1, IRAK2, IRF1, ISL1, ITGAM, ITPR1, JUN, KLKB1, LTF, SMAD3, SERPINE1, SERPINF1, PENK, CFP, SERPINB9, PPP2R5D, PRKACB, PRKACG, PRKCE, PROC, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTGIS, PTPN6, PVR, RAF1, RPS6KA1, RPS19, S100A8, S100A9, S100A12, SERPINB4, XCL1, CX3CL1, SELE, SKP1, STAT5B, XCL2, TNFRSF1A, TNFRSF1B, HSP90B1, TNFSF4, TYRO3, UBB, UBE2D2, SUMO1, SCGB1A1, NR1H2, VAV1, VTN, CUL1, IKBKG, VAMP8, RIPK1, RIPK2, TNFSF18, SOCS3, UBA3, IL1RL1, KLF4, SLIT2, PSMF1, CLOCK, TRIL, NR1H4, NR1D2, PSME3, PSMD14 |
899 | GO:0001763 | 0.00 | 2.32 | 25.05 | 44 | 106 | morphogenesis of a branching structure | AGTR2, RERE, BAX, PRDM1, BMP4, CAV3, CD44, CTNND2, CTSH, EDNRA, EPHA2, ETV4, ETV5, FGF7, B4GALT1, GPC3, GRB2, HGF, HHEX, FOXA2, IGF1, IHH, IL10, ILK, KDR, LLGL2, PGR, PSPN, RXRA, SALL1, SLC12A2, SOX9, SOX10, SRF, ST14, WNT1, FZD5, TP63, NRP1, SOCS3, SLIT2, SEMA3E, FEM1B, SPRY1 |
900 | GO:0032414 | 0.01 | 2.32 | 8.51 | 15 | 36 | positive regulation of ion transmembrane transporter activity | BMP4, CALM3, DNM2, KCNJ11, NTSR1, PTAFR, RYR2, S100A1, SLC9A1, SUMO1, RGN, GSTO1, AKAP7, AKAP6, AKAP9 |
901 | GO:0002520 | 0.05 | 2.32 | 5.07 | 9 | 22 | immune system development | C3, CBLB, CLC, IDO1, SMAD3, UNG, RNF8, EXO1, IL27RA |
902 | GO:0097285 | 0.00 | 2.32 | 17.00 | 30 | 73 | cell-type specific apoptotic process | ABL1, ABL2, APOH, BMPR2, CAMK2A, KRIT1, COL4A3, FAP, FGA, GNGT1, NRG1, HMGCR, ICAM1, IGF1, IL12B, IL13, KDR, SERPINE1, SERPINB13, RYR2, SORT1, SIX3, SOX9, SCG2, CUL3, API5, AKR1C3, STK17B, STK17A, BAG3 |
903 | GO:0015909 | 0.04 | 2.31 | 5.67 | 10 | 24 | long-chain fatty acid transport | ACACB, ABCD1, ANXA1, CD36, CPT1B, CPT2, ACE, DRD3, NTSR1, ABCD3 |
904 | GO:0042771 | 0.04 | 2.31 | 5.67 | 10 | 24 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | BCL3, BRCA2, CD44, CDKN1A, EP300, IFI16, ING2, TP73, DYRK2, TP63 |
905 | GO:0051926 | 0.04 | 2.31 | 5.67 | 10 | 24 | negative regulation of calcium ion transport | ATP1A2, CALM3, CASQ2, CAV3, ICAM1, NTSR1, PLN, SPINK1, STC1, GSTO1 |
906 | GO:0006415 | 0.00 | 2.31 | 15.36 | 27 | 65 | translational termination | EIF5A, FAU, UPF1, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, RPL14, RPL23 |
907 | GO:0001101 | 0.00 | 2.31 | 17.04 | 30 | 73 | response to acid chemical | ABCA1, ABL2, BMP4, CD9, AKR1C4, CTSH, BRINP1, DHFR, DUSP1, PTK2B, HLCS, KRT13, NTRK3, SERPINF1, RARA, RXRA, SHMT1, SIPA1, SOX9, SP100, SPARC, SCGB1A1, WNT11, ZNF35, SLC14A2, SLC10A3, FZD4, FZD7, OGT, KLF4 |
908 | GO:0007093 | 0.01 | 2.31 | 10.79 | 19 | 46 | mitotic cell cycle checkpoint | BCL2L1, BUB1B, CCNB1, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DUSP1, PRCC, RB1, RPL24, TTK, ZNF207, SMC1A, CDC23, CDC16, ZW10, MAD2L1BP |
909 | GO:0007265 | 0.00 | 2.31 | 41.86 | 73 | 178 | Ras protein signal transduction | ANGPT1, ARAF, CALM3, CAMK2A, CDK2, CDKN1A, CRKL, CSF2RB, DNM2, DOK1, DUSP5, FGF3, FGF4, FGF7, FGFR3, FYN, GDI1, GRB2, RAPGEF1, GRIN2A, IL2RA, KIT, MARK3, PPP2CB, PPP5C, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTK2, PTPRA, RALA, RAP2A, RAP2B, RASA2, RB1, RIT1, RSU1, SHC1, UBB, FGF23, OGT, PEA15, DOK2, USP8, GRAP2, PSMF1, NRG2, AATK, RALGPS1, RAPGEF2, RBX1, AKAP9, G3BP1, ABI2, RASA4, WASF2, PSME3, PSMD14, SPRY1 |
910 | GO:0048589 | 0.01 | 2.31 | 10.20 | 18 | 44 | developmental growth | ANXA1, BMPR1A, CCNE1, CHAT, DMBT1, GAS1, GPX1, LIPC, SMAD3, PRKCQ, RAD51B, SOX10, TBCE, TYMS, EIF4H, FZD7, ADAM15, GINS1 |
911 | GO:0042475 | 0.01 | 2.30 | 9.69 | 17 | 41 | odontogenesis of dentin-containing tooth | ACVR2B, AMBN, BAX, BMP4, BMPR1A, BSG, RUNX2, CHUK, CTNNA1, EDA, FGF4, SCN5A, SLC34A1, TP63, HAND1, KLK4, BCL2L11 |
912 | GO:0051952 | 0.01 | 2.30 | 9.69 | 17 | 41 | regulation of amine transport | ABAT, AGTR2, ARG1, ATP1A2, CACNA1A, CHRNB2, CNR1, CRH, DRD3, FFAR3, NTSR1, OXTR, P2RX7, PCP4, PTGS1, RAB3B, SNCA |
913 | GO:0002768 | 0.00 | 2.30 | 21.67 | 38 | 93 | immune response-regulating cell surface receptor signaling pathway | ANGPT1, ARAF, BAD, CAMK2A, CASP9, CD86, CDKN1A, CREB1, CSF2RB, DUSP5, FCGRT, FGF3, FGF4, FGF7, FGFR3, GRIN2A, NRG1, NR4A1, IL2RA, JUN, KIT, MARK3, KITLG, FOXO4, PPP5C, PTPRA, RASA2, RPS6KB2, SHC1, FGF23, CUL3, PEA15, NRG2, RAPGEF2, GAB2, RBX1, AKAP9, RASA4 |
914 | GO:0006333 | 0.00 | 2.29 | 14.85 | 26 | 63 | chromatin assembly or disassembly | HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, HIST1H1A, HMGA1, SET, SMARCA4, SMARCD3, SMARCE1, SOX9, TAL1, TSPY1, CHAF1B, HIST1H2BL, HIST1H2BN, HIST1H2BM, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H3F, BAZ1B |
915 | GO:0007173 | 0.00 | 2.29 | 54.36 | 94 | 230 | epidermal growth factor receptor signaling pathway | ABL1, ABL2, ADAM10, ANGPT1, APLP2, APP, ARAF, BAD, CALM3, CAMK2A, CASP9, CBL, CD28, CD86, CDKN1A, CHUK, AP2S1, CREB1, CSF2RB, DUSP5, EPS15, PTK2B, EFEMP1, FGF3, FGF4, FGF7, FGFR3, FYN, GRB2, GRB7, GRIN2A, NRG1, NR4A1, IL2RA, ITGA1, ITPR1, KIT, MARK3, KITLG, FOXO4, PPP5C, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, PTPRA, PTPRJ, RAF1, RASA2, RPS6KB2, SHC1, SOX9, ADAM17, UBB, VAV1, VIL1, FGF23, CUL3, PEA15, ARHGEF7, REPS2, PSMF1, NRG2, BCAR1, RAPGEF2, RBX1, AKAP9, RASA4, PSME3, PSMD14, SPRY1, STAM2 |
916 | GO:0036297 | 0.03 | 2.29 | 6.85 | 12 | 29 | interstrand cross-link repair | ATR, ERCC4, FANCE, FANCB, FANCF, FANCG, RAD51D, RPA2, RPA3, UBB, RNF8, DCLRE1A |
917 | GO:0070373 | 0.03 | 2.29 | 6.85 | 12 | 29 | negative regulation of ERK1 and ERK2 cascade | ABL1, CRYBA1, DUSP1, FBLN1, RAPGEF1, IGF1, PTPRR, ITGB1BP1, KLF4, SLC9A3R1, RANBP9, SPRY1 |
918 | GO:0086010 | 0.03 | 2.29 | 6.85 | 12 | 29 | membrane depolarization during action potential | ATP1A2, CACNA1A, CACNA1B, CAV3, KCNH2, KCNJ2, SCN1A, SCN2A, SCN4B, SCN5A, SCN7A, SCN8A |
919 | GO:0002474 | 0.00 | 2.29 | 14.89 | 26 | 63 | antigen processing and presentation of peptide antigen via MHC class I | CANX, CD36, CYBA, ACE, ITGAV, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, UBB, PSMF1, PSME3, PSMD14 |
920 | GO:0007268 | 0.00 | 2.28 | 38.50 | 67 | 166 | synaptic transmission | AMPH, CALM3, AP2S1, CNP, COMT, DBH, DLG2, DLG3, GABRA5, GABRG1, GABRR1, GABRR2, GNG3, GNG10, GNGT1, GNGT2, GPR1, GRIA4, GRM1, HTR2C, KCNA1, KCNA3, KCNA4, KCNC2, KCND2, KCND3, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ11, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN4, KCNQ1, KCNS2, KCNS3, KIF5A, ATXN3, OMP, PCDH8, PDYN, PRKACB, RAF1, RPS6KA1, SNCB, SYPL1, SYT5, KCNAB1, BSN, UNC119, USP14, KCNAB3, KCNK6, APBA3, GABBR2, SNAP91, SLC12A6, HCN4, ABCC9, AKAP9, KCNMB2 |
921 | GO:0043207 | 0.00 | 2.28 | 114.86 | 195 | 486 | response to external biotic stimulus | ABCA1, ABL1, ADAR, ADH5, ALAD, ANG, ANXA3, ANXA5, BIRC3, APP, KLK3, ARF1, ARG1, ASS1, ATP4B, AXL, BAD, BCL2L1, BCL3, BCR, PRDM1, BNIP3L, BPI, BST2, BYSL, TSPO, CASP9, CD4, CD6, CD8A, CD28, CD86, TNFRSF8, TNFSF8, CD36, CD37, ENTPD2, CDK6, CEBPE, CHUK, AP1S1, AP2S1, CLU, CNP, CNR1, COMT, COX8A, CPS1, CRP, CX3CR1, CXADR, CYBA, DCN, DDX1, DMBT1, DNMT1, EDNRA, F2R, F3, FAU, FCN2, FGA, FGF7, FGR, FYN, GABRA5, GPX1, CXCL3, HMGCS2, HMGA1, HP, HRG, HSPB1, ICAM1, IFI16, IFIT1, IFIT3, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNGR1, IFNW1, IGF1, RBPJ, IL2RA, IL10, IL10RA, IL12B, IL12RB2, IL13, IL18, IDO1, IRAK1, IRAK2, IRF1, IRF5, ISG20, JUN, JUND, KCNJ8, KCNQ1, LTF, SMAD3, NTHL1, OAS3, P2RX7, P2RY2, SERPINE1, PCBP2, PDE4B, PDK4, PENK, PEX13, PF4V1, CFP, SERPINB9, PPM1B, PRG2, PRKCE, PSMA2, PTAFR, PTGER1, PTGER2, RAB1A, RAC1, RARA, UPF1, RPL39, RPS6KB1, S100A7, S100A8, S100A9, S100A12, SCN1A, CCL22, CXCL6, CXCL5, XCL1, SEC14L1, SELE, SELP, SFTPD, SLPI, SNCA, SNRPD1, SPARC, STAT2, STAT5B, ADAM17, TNFRSF1A, TNFRSF1B, TPT1, TNFSF4, SCGB1A1, VIL1, VIP, TRIM25, ZNF189, FZD5, FOSL1, CHAF1B, HIST2H2BE, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, OGT, PPM1D, PARG, IKBKG, RIPK2, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, AP1M1, HIST1H3F, SOCS3, DDX21, IL27RA, CHST3, ATG5, ADAMTS4, LITAF, NUP93, PHYHIP, NR1H4, FGFBP1, BCL2L11, AP1M2, ABCC9, IL18BP |
922 | GO:0009725 | 0.05 | 2.28 | 5.07 | 9 | 23 | response to hormone | ANG, CBLB, PTK2B, HCLS1, ICAM1, ITGB1, OXCT1, SORD, SRF |
923 | GO:0034284 | 0.01 | 2.28 | 9.16 | 16 | 39 | response to monosaccharide | ACVR2B, ANGPT2, CAT, COL6A2, CTGF, EIF2B1, PTK2B, GYS2, HMGCS2, PRKCQ, PTEN, RPS6KB1, SPARC, SREBF1, EIF2B3, EIF2B2 |
924 | GO:0010001 | 0.01 | 2.27 | 10.32 | 18 | 44 | glial cell differentiation | ABL1, ABL2, CDK6, EGR2, EMX1, F2, GFAP, HMBS, IGF1, ILK, NTRK3, S100A8, S100A9, STAT3, VIM, RNF112, PHOX2B, PICK1 |
925 | GO:0007422 | 0.02 | 2.27 | 8.04 | 14 | 34 | peripheral nervous system development | ALDH3A2, ADGRB2, EGR2, EGR3, NRG1, HOXD9, HOXD10, ILK, ISL1, NTRK2, SCN8A, SOX10, TBCE, ONECUT2 |
926 | GO:0002683 | 0.00 | 2.27 | 28.26 | 49 | 120 | negative regulation of immune system process | ADAR, ANGPT1, AXL, BCR, PRDM1, BPI, BST2, CBLB, CD86, CD37, CD59, CNR1, TSC22D3, GPX1, IFI16, IFIT1, IGF2, IL2RA, IL10, IL12B, IL13RA2, IDO1, INS, KITLG, PCBP2, SERPINB9, PPM1B, PRKAR1A, PSMB4, PTPN6, PTPRJ, RPS19, SERPINB4, CCL21, CCL25, XCL1, SEC14L1, SFTPD, SOX9, SOX11, STAT6, TYRO3, SCGB1A1, NR1H2, PDE5A, IL1RL1, SOCS6, SLIT2, IL27RA |
927 | GO:0008361 | 0.00 | 2.27 | 23.63 | 41 | 100 | regulation of cell size | ABL1, ADD1, ARHGAP4, ATP2B2, BMPR2, CAV3, CDK4, CLCN3, CLCN6, CLNS1A, CREB1, DCC, DNM2, EFNA5, CTTN, GOLGA4, NRG1, ILK, KCNN4, LIMK1, NRCAM, NTRK3, P2RX7, PTEN, RAC1, RNF6, SEMA3F, SRF, TNR, TP73, TSC1, VAV1, SEMA3B, RND2, OGT, NRP1, SLIT2, SLC9A3R1, AATK, SEMA3E, RB1CC1 |
928 | GO:0006935 | 0.00 | 2.27 | 80.60 | 138 | 347 | chemotaxis | ABL1, ABL2, ACTB, APP, ARAF, CACNB4, CALM3, CAMK2A, CD72, CHN1, AP2S1, CCR3, CCR8, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2RB, CSNK2A1, CSNK2A2, DCC, DLG3, DLX5, DNM1, DPYSL3, DUSP5, TYMP, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EPHA5, EPHA8, EPHB2, EPHB3, ETV4, FGF3, FGFR3, FPR1, FPR3, FYN, GFRA1, XCR1, GRB2, GRIN2A, NRG1, IL2RA, ISL1, ITGA5, ITGAV, ITGB1, KIF5A, LIMK1, MARK3, KITLG, NRCAM, NTN3, OTX2, PPP5C, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTAFR, PTK2, PTPRA, RAF1, RALA, RASA2, RNASE2, RPL24, RPS6KA1, RYK, SCN5A, SEMA3F, SHC1, SOS2, CNTN2, TNR, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, SEMA3B, FOSL1, FGF23, CUL3, CNTNAP1, KLF7, UNC5C, NUMB, PEA15, NRP2, ARHGEF7, RPS6KA4, USP14, NRXN3, NRXN1, PSMF1, NRG2, FEZ2, RAPGEF2, SEMA3E, ARHGEF11, RBX1, RANBP9, ARPC5, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, PSME3, PSMD14 |
929 | GO:0045807 | 0.01 | 2.27 | 9.19 | 16 | 39 | positive regulation of endocytosis | ARF1, AXL, BCR, C3, CD36, CYBA, DNM2, GPC3, ITGAV, ITGB1, RAB27A, RAP1GAP, SFTPD, SNCA, TSG101, TULP1 |
930 | GO:0071897 | 0.01 | 2.26 | 9.20 | 16 | 39 | DNA biosynthetic process | CENPF, CTGF, DNTT, PCNA, REV3L, RFC3, RFC4, RFC5, RPA2, RPA3, TYMS, UBB, UBA7, TRIM25, CUL4A, RBX1 |
931 | GO:0050878 | 0.00 | 2.26 | 66.40 | 114 | 285 | regulation of body fluid levels | ABL1, ACTB, ACTN1, APLNR, ALB, ANGPT1, ANGPT2, APP, ATP2A1, ATP2B1, ATP2B3, AXL, BSG, C3, DAGLA, CALM3, CD9, ENTPD2, CD44, CD58, CD59, CD63, CDK2, CENPE, CLU, COL1A1, CSRP1, CXADR, DGKB, EMP2, EPHB2, F2RL2, F10, FBLN1, FGR, FYN, GATA4, GATA6, GNA15, GNAI1, GNAQ, GP9, GRB2, GRB7, HBD, HBE1, HGF, HSPB1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IGF1, IGF2, ILK, IRF1, ITGA1, ITGA4, ITGA5, ITGAM, ITGAV, ITGB1, ITPR1, KIF5A, LAMP2, OLR1, P2RX1, SERPINA5, PF4V1, PRCP, PSAP, PTK2, PTPN6, RAB5A, RAB27A, RAC1, RAC2, RAD51C, RAD51B, RAF1, RAP2B, CX3CL1, SELE, SELL, SELPLG, SHC1, SLC8A3, SPARC, STXBP3, TRPC3, TUBA4A, TYRO3, VAV1, VEGFB, YWHAZ, SLC7A5, AKAP1, FZD6, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, AP3B1, PDE5A, PROZ, HIST1H3F, DOK2, DGKI, KIF3B, BCAR1, GNA14, KCNMB2, ABCC4 |
932 | GO:0051817 | 0.00 | 2.26 | 14.39 | 25 | 61 | modification of morphology or physiology of other organism involved in symbiotic interaction | ALB, BAD, BCL2L1, CD4, FBLN1, ITGAV, KPNA1, KPNA2, KPNA3, KPNA4, LTF, SMAD3, NUP98, SERPINB9, PPIB, RANBP2, RXRA, TYMS, NUP214, AAAS, VAPB, RAB9A, NUP155, NUP93, BCL2L11 |
933 | GO:0060759 | 0.00 | 2.26 | 19.62 | 34 | 83 | regulation of response to cytokine stimulus | ADAR, ANGPT1, BIRC3, AXL, CHUK, ECM1, UBE2K, HPX, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNGR1, IL1RN, IRAK1, IRAK2, PTPN6, STAT2, TNFRSF1A, TRAF1, TRAF2, UBB, SUMO1, NR1H2, IKBKG, TRADD, RIPK1, RIPK2, TAX1BP1, SOCS3, KLF4, SLIT2 |
934 | GO:0071804 | 0.00 | 2.26 | 27.18 | 47 | 115 | cellular potassium ion transport | ATP1A1, ATP1A2, ATP1A3, ATP12A, FXYD2, ATP4A, CASQ2, CAV3, CNGA1, DNM2, DPP6, KCNA1, KCNA3, KCNA4, KCNC2, KCND2, KCND3, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN4, KCNQ1, KCNS2, KCNS3, REST, SUMO1, KCNAB1, KCNAB3, KCNK6, AKAP7, AKAP6, OXSR1, SLC12A6, HCN4, ABCC9, AKAP9, KCNMB2 |
935 | GO:0006026 | 0.01 | 2.26 | 9.22 | 16 | 39 | aminoglycan catabolic process | CD44, VCAN, CSPG4, DCN, GPC4, GALNS, GPC3, HEXA, HEXB, IDS, IDUA, OMD, OVGP1, SDC4, SLC9A1, SDC3 |
936 | GO:1901989 | 0.01 | 2.26 | 9.22 | 16 | 39 | positive regulation of cell cycle phase transition | ANXA1, BIRC5, APP, CDK4, PTEN, RAD51C, RAD51B, RB1, SMARCD3, UBE2E2, ZNF16, CUL4A, CUL3, TP63, PHOX2B, DLGAP5 |
937 | GO:0070489 | 0.00 | 2.26 | 56.01 | 96 | 237 | T cell aggregation | ABL1, ABL2, ANXA1, BAD, BAX, BCL3, BMP4, ZFP36L2, RUNX2, CBLB, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD7, CD8A, CD28, CD86, TNFSF8, CD59, CD151, CDK6, CLC, CTLA4, CXADR, DPP4, EFNB1, EGR3, FLOT2, FLT3, FYN, GRB2, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF2, IHH, IL2RA, IL10, IL12B, IL18, IDO1, INS, IRF1, ITGAD, KIT, LMO1, SMAD3, P2RX7, PRKAR1A, PRKCQ, PTPN6, RAB27A, RAC1, RAC2, RAG1, RAG2, RARA, RPL22, SATB1, CCL21, XCL1, SFTPD, SOS2, SRF, STAT5B, STAT6, ADAM17, TRAF2, TSC1, TNFSF4, SCGB1A1, VAV1, WNT1, FZD5, FZD7, FZD8, AP3B1, PDE5A, STX11, TNFSF14, TNFSF9, RIPK2, AP3D1, TNFSF18, SOCS6, GRAP2, SOX13 |
938 | GO:1902107 | 0.01 | 2.26 | 10.37 | 18 | 44 | positive regulation of leukocyte differentiation | ANXA1, AXL, BAD, PRDM1, BTK, CD86, EGR3, FLT3LG, IHH, IL2RA, RAG1, RARA, STAT5B, TNFSF4, AP3B1, TNFSF9, RIPK2, AP3D1 |
939 | GO:0099536 | 0.00 | 2.25 | 96.19 | 163 | 407 | synaptic signaling | ABAT, AMPH, ARF1, ATP1A2, ATP2B2, BCHE, TSPO, CACNA1A, CACNA1B, CACNB4, CALM3, CAMK2A, CDC20, CDH8, CHAT, CHRM1, CHRM3, CHRNB2, CHRNB4, AP2S1, CLCN3, CNP, CNR1, COMT, CREB1, CRH, CRHBP, CTNND2, CX3CR1, DBH, DBI, DLG2, DLG3, DNM1, DRD3, DRD5, DTNA, EGR2, EGR3, ETV5, PTK2B, GABRA4, GABRA5, GABRG1, GABRR1, GABRR2, GAD1, GFAP, GLRA1, GNAI1, GNG3, GNG10, GNGT1, GNGT2, GPR1, GRIA1, GRIA4, GRID2, GRIN2A, GRM1, HRH1, HTR2C, IFNG, KCNA1, KCNA3, KCNA4, KCNC2, KCND2, KCND3, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN4, KCNQ1, KCNS2, KCNS3, KIF5A, KISS1, KIT, ATXN3, NTRK2, NTSR1, OMP, OXTR, P2RX1, P2RX3, P2RX4, P2RX7, P2RY11, PCDH8, PDYN, PFN2, SEPT5, PRKACB, PRKCE, PTEN, PTN, PTPRN2, RAB3B, RAB5A, RAC1, RAC3, RAF1, RARA, RPS6KA1, CX3CL1, SLC1A6, SLC6A13, SLC8A3, SLC22A2, SNAP25, SNCB, SNCA, SRF, STAU1, SYN1, SYP, SYPL1, SYT1, SYT4, SYT5, CNTN2, TNR, KCNAB1, SYN3, STX11, LIN7A, SYNJ1, BSN, UNC119, USP14, SLC6A5, DGKI, KCNAB3, SNAP29, NRXN3, NRXN1, NRXN2, KCNK6, PICK1, APBA3, GABBR2, RIN1, SNCAIP, RAPGEF2, RIMS2, EIF4A3, SNAP91, SLC12A6, HCN4, ABCC9, AKAP9, KCNMB2 |
940 | GO:0043900 | 0.02 | 2.25 | 7.47 | 13 | 32 | regulation of multi-organism process | CNR1, CYBA, FCER2, B4GALT1, GLRA1, OXTR, P2RX7, P2RY2, PPP2R1A, PTAFR, SPINK1, VIP, PDE5A |
941 | GO:0040012 | 0.00 | 2.25 | 16.08 | 28 | 70 | regulation of locomotion | ABL1, ABL2, ANXA1, ANXA5, BBS4, CDK6, CHRM1, ACE, DRD3, ECM1, EFNA1, EPHA2, EMP2, EFEMP1, FGF4, LAMA3, LAMA4, PRCP, PRKX, RAF1, SDC4, SGK1, SNCA, STK10, SOX14, UNC5C, USP14, SLK |
942 | GO:0051781 | 0.00 | 2.25 | 15.60 | 27 | 66 | positive regulation of cell division | BIRC5, CAT, CD28, DRD3, FGF3, FGF4, FGF7, OPN1MW, IGF1, IGF1R, IGF2, IL1A, INS, YBX1, PRKCE, PTEN, PTN, RB1, OPN1LW, TAL1, VEGFB, ZNF16, CUL3, AURKB, ITGB1BP1, KIF3B, DLGAP5 |
943 | GO:0001708 | 0.01 | 2.25 | 10.40 | 18 | 44 | cell fate specification | ASCL1, BMPR1A, EVX1, EYA2, FOXA2, HOXC10, HOXD10, RBPJ, IHH, ISL1, ITGB1, NTRK3, OTX2, SOX9, FZD7, PTCH2, NRP1, OLIG2 |
944 | GO:0016032 | 0.00 | 2.24 | 50.10 | 86 | 216 | viral process | TRIM23, ARF1, BAX, BICD1, BNIP3L, CCNT2, CDC25C, CENPA, AP1S1, AP2S1, CCR3, CREB1, CX3CR1, DMBT1, E4F1, EPHA2, EIF4A1, EIF4E, FDPS, FYN, KAT2A, GRB2, HMGA1, HPX, SP110, KDR, IPO5, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, RAB6A, RAC1, RALA, RANBP1, RB1, SATB1, SET, SHC1, SKP1, STAT2, STAT3, TAF4B, TAF10, TBP, TSPAN7, TNFRSF1A, TOP1, TP73, UBE3A, SUMO1, UNG, VIM, EIF4H, XRCC5, CUL4A, CUL2, CUL1, IKBKG, DYNLL1, EIF4G3, AP1M1, CLDN6, PSMF1, KDM4A, CUL7, RBX1, AP1M2, RAD50, ABI2, WASF2, PSME3, PSMD14 |
945 | GO:0007050 | 0.00 | 2.24 | 17.36 | 30 | 74 | cell cycle arrest | ABL1, AK1, BARD1, DST, CDK6, BRINP1, DUSP1, E4F1, EIF4G2, GAS1, GAS2, IFNG, IFNW1, IL12B, ILK, INHA, IRF1, SMAD3, PA2G4, PRKAA1, PRKAG1, RB1, RHEB, TSC1, TSG101, CUL4A, CUL3, CUL2, CUL1, GAS7 |
946 | GO:0007188 | 0.00 | 2.24 | 19.14 | 33 | 81 | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | ADRA1B, AVPR2, CHRM1, CHRM3, CCR3, CNR1, DRD3, DRD5, S1PR1, LPAR1, FPR1, FSHR, GALR1, GCG, GCGR, GHRHR, GNAI1, GNAQ, GNAS, GNAT1, GNAT2, GPR3, GPR26, FFAR3, PRKACB, PSAP, PTGER2, VIP, S1PR4, GLP2R, SLC9A3R1, RAPGEF2, WASF2 |
947 | GO:0034446 | 0.01 | 2.24 | 11.58 | 20 | 49 | substrate adhesion-dependent cell spreading | ABL1, AXL, DNM2, EFNA1, EPHB3, FBLN1, FGA, ILK, ITGA4, ITGAV, PTK2, RAB1A, RAC1, RAC3, TYRO3, FZD4, FZD7, ARHGEF7, ITGB1BP1, ARPC2 |
948 | GO:0044728 | 0.01 | 2.24 | 11.58 | 20 | 49 | DNA methylation or demethylation | ATRX, DNMT1, DNMT3B, GNAS, MGMT, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, FKBP6, ALKBH1, HIST1H3F, PICK1 |
949 | GO:0001503 | 0.00 | 2.24 | 19.70 | 34 | 84 | ossification | ADAR, BMP1, BMP3, BMP8B, CAT, COL1A1, COL6A1, COL11A1, VCAN, CTGF, CTSK, EPHA2, EXT2, GPLD1, HNRNPC, IGF2, IGFBP3, IHH, INPPL1, PCP4, PENK, PEX7, PSMC2, RPL38, RPS11, RYR1, SORT1, SLC34A1, SNAI1, SP1, SPARC, STC1, DDX21, NR1I3 |
950 | GO:0007589 | 0.04 | 2.24 | 6.36 | 11 | 27 | body fluid secretion | COPA, CYBA, GUCA2B, P2RY2, PRKCE, SLC22A2, TP73, NR1H2, VIP, VAMP8, ATG5 |
951 | GO:0001667 | 0.00 | 2.24 | 46.79 | 80 | 198 | ameboidal-type cell migration | ACVRL1, AGTR2, ANGPT1, ANGPT2, ANXA3, APOH, ARHGAP4, ARHGDIB, BMP4, BMPR2, KRIT1, CD63, CTSH, DCN, DPP4, EFNA1, EFNB1, EGR3, EPHA2, EMP2, ETS1, PTK2B, FAP, FGF4, FGF7, FLT4, GPLD1, GPX1, NR4A1, HRG, HSPB1, IFNG, ILK, ISL1, ITGA4, ITGB1, JUN, KDR, KIT, KRT2, KITLG, PAX3, SERPINF1, PFN2, PRCP, PRKCE, PRKD1, PRKX, PTEN, PTK2, PTPRR, RAC1, S100A2, SDC4, SEMA3F, SOX9, SOX10, SP100, SPARC, SRF, STC1, NR2F2, VIL1, WNT11, SCG2, SEMA3B, NRP2, NRP1, ARHGEF7, PHOX2B, ITGB1BP1, KLF4, SLIT2, BAG4, BCAR1, SEMA3E, ZEB2, HDAC6, PDCD6, WASF2 |
952 | GO:0097306 | 0.00 | 2.24 | 13.91 | 24 | 59 | cellular response to alcohol | ABCA1, ATP2B1, BGLAP, KLF9, CDH1, CRHBP, CTNNA1, ELK1, GLRA1, GPLD1, IGF1, IL10, ITGB1, PENK, PIM1, PRKAA1, PRKCE, PTAFR, PTN, RAD51, FGF23, NRIP1, KLF4, RAMP3 |
953 | GO:0045937 | 0.00 | 2.24 | 135.24 | 226 | 576 | positive regulation of phosphate metabolic process | ABL1, ABL2, ACVR2B, ACVRL1, ADRA1B, AGTR2, ALK, ANG, ANGPT1, ARAF, ATP6AP1, BAD, BAX, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, C3, CAMK2A, CCNB1, CCNC, CCNT2, CD3E, CD4, CD36, CD44, CDKN1A, CENPE, CLU, CRKL, CSF1R, CSF2RB, CSNK1D, CSPG4, CTF1, CTGF, ACE, DUSP5, LPAR1, EFNA1, EFNA5, EMP2, EPHA8, ERCC6, F2, F2R, PTK2B, FGA, FGF3, FGF4, FGF7, FGFR3, FGR, FLT1, FLT3, FLT3LG, FLT4, FPR1, FYN, GDF9, GNG3, GPLD1, GRB2, RAPGEF1, GRIN2A, GRM1, HCLS1, HGF, NRG1, UBE2K, HMGCR, HPX, HRH1, HTR2C, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1R, IGF2, IGFBP3, IL1A, IL2RA, IL12B, IL13, IL18, ILK, INHA, IRAK1, IRAK2, ISL1, ITGA1, ITGA5, ITGB1, JUN, KDR, KISS1, KIT, LTF, SMAD3, MARK3, KITLG, MAP3K11, PPP1R12A, NTRK3, NTSR1, PFN2, PIM1, PPP5C, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRKD1, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTAFR, PTEN, PTK2, PTPRA, RAC1, RAP2A, RAP2B, RASA2, RPS3, RYK, S100A7, S100A12, CCL21, CCL22, CCL25, XCL1, CX3CL1, SDC4, SHC1, STIL, SNCA, SOX9, STK10, XCL2, ADAM17, TNFRSF1A, TNFRSF1B, TP73, TPD52L1, TRAF2, TTK, UBB, VEGFB, VTN, WNT1, WNT11, ZNF16, FZD5, ARHGEF5, FGF23, CDK2AP1, FZD4, FZD7, FZD8, BCAR3, CUL3, OGT, IKBKG, PDE5A, PEA15, RIPK1, RIPK2, TNFRSF18, TNFRSF10B, TNFRSF10A, NRP1, RPS6KA4, TNFSF18, UNC119, RGN, LATS1, ARHGEF2, VAPB, ITGB1BP1, GPR55, AKAP6, PSMF1, GDF15, BAG4, NRG2, TRAF4, RAPGEF2, SLK, ATG13, RB1CC1, ZEB2, OXSR1, TNFSF15, RBX1, RAD50, AKAP9, RASA4, PSME3, PSMD14 |
954 | GO:0009749 | 0.02 | 2.24 | 7.52 | 13 | 32 | response to glucose | ACVR2B, ANGPT2, COL6A2, CTGF, EIF2B1, PTK2B, GYS2, PRKCQ, PTEN, RPS6KB1, SREBF1, EIF2B3, EIF2B2 |
955 | GO:0002761 | 0.04 | 2.24 | 6.36 | 11 | 27 | regulation of myeloid leukocyte differentiation | BGLAP, FSHB, FSHR, INHA, LTF, RARA, TAL1, TYROBP, CUL4A, INPP4B, GPR55 |
956 | GO:0001568 | 0.00 | 2.23 | 68.85 | 117 | 292 | blood vessel development | ACVR2B, ACVRL1, ANG, ANGPT1, ANGPT2, ANXA3, APOH, KLK3, ADGRB2, BAX, BMP4, BMPR2, KLF5, C3, KRIT1, CDX2, CCR3, COL1A1, COL4A3, COL15A1, CRKL, CSPG4, CTGF, CTSH, CX3CR1, DCN, DHCR7, TYMP, ECM1, S1PR1, EDNRA, EFNA1, EGR3, EPHA2, EMP2, EPHB1, EPHB2, EPHB3, ETS1, F3, PTK2B, FAP, FLT1, FLT4, GATA4, B4GALT1, GJA4, GPLD1, GPX1, RAPGEF1, GTF2I, HGF, HHEX, NR4A1, HPGD, HRG, HSPB1, RBPJ, IHH, IL1A, IL18, ISL1, ITGA5, ITGAV, ITGB1, JUN, KDR, LLGL2, SMAD7, MEOX2, FOXO4, NRCAM, NTRK2, SERPINE1, SERPINF1, PRCP, PRKD1, PRKX, PTEN, PTGIS, PTK2, PTN, PTPRJ, S100A7, CX3CL1, SHB, SHC1, SP100, SPARC, SRPK2, TAL1, NR2F2, TNNI3, WNT11, VEZF1, FZD5, SCG2, FOSL1, FZD4, FZD8, SERPINB7, ADAM15, NRP2, SOCS3, ITGB1BP1, KLF4, SLIT2, NRXN3, NRXN1, HAND1, EIF2AK3, RAPGEF2, SEMA3E, CUL7, SLC12A6, PDCD6, WASF2 |
957 | GO:0007292 | 0.00 | 2.23 | 12.76 | 22 | 54 | female gamete generation | ANG, BRCA2, CCNB1, DIAPH2, PTK2B, FSHB, FSHR, GDF9, HEXB, HPGD, IGF1, IHH, IL1R1, PGR, PPP2R1A, TAF4B, FOSL1, NRIP1, USP9X, PDE5A, DYNLL1, REC8 |
958 | GO:0060333 | 0.04 | 2.23 | 6.37 | 11 | 27 | interferon-gamma-mediated signaling pathway | CAMK2A, CD44, ICAM1, IRF1, IRF5, CIITA, OAS3, PTAFR, SP100, TRIM21, TRIM25 |
959 | GO:0007417 | 0.00 | 2.23 | 14.97 | 26 | 66 | central nervous system development | ALDH3A2, TPP1, VCAN, RCAN1, EPHB1, F2, GABRA4, GFAP, HMBS, JARID2, MAL, NRCAM, NTRK3, PAM, PCP4, PSPN, PTK2, S100A8, S100A9, SEMA3F, SPOCK1, STAT3, VIM, RNF103, JRKL, VNN2 |
960 | GO:0048565 | 0.02 | 2.23 | 7.53 | 13 | 32 | digestive tract development | ASCL1, ASS1, CCNB1, CPS1, HMGCS2, KIT, OXTR, PCSK5, RARB, RB1, RXRA, SALL1, NR1H4 |
961 | GO:0048592 | 0.00 | 2.23 | 15.10 | 26 | 64 | eye morphogenesis | AQP5, BAX, BBS4, PRDM1, BMP4, CRYGB, EPHA2, FGFR3, GNAT1, GNAT2, GNGT1, HMGN1, KDR, NTRK2, OTX2, PRKCI, PTN, RPGR, SOX9, STAT3, TULP1, YY1, BCAR3, SLC4A7, NR2E3, IRX5 |
962 | GO:0030282 | 0.00 | 2.23 | 13.94 | 24 | 59 | bone mineralization | ACVR2B, BGLAP, BMP4, BMPR1A, BMPR2, ECM1, S1PR1, PTK2B, FGFR3, GPC3, IGF1, LTF, SMAD3, OMD, P2RX7, PTN, SOX9, KLF10, CLEC3B, TUFT1, WNT11, FGF23, EIF2AK3, MINPP1 |
963 | GO:0097190 | 0.00 | 2.23 | 36.14 | 62 | 155 | apoptotic signaling pathway | ABL1, ANXA6, XIAP, ARHGAP4, ATF4, ATP2A1, BCL2A1, BCL3, BNIP3L, BOK, BRCA2, BTK, CASP9, CD3E, CD5, CD28, TNFRSF8, CD70, CDKN1A, CRH, DCC, DDX5, EPHA2, EP300, ERCC6, EYA2, FGD1, FGFR3, HIC1, HIP1, UBE2K, IFI16, IFNG, ITPR1, JUN, KITLG, P2RX4, P2RX7, PTGIS, RAC1, DPF2, SORT1, SCN2A, SOS2, TNFRSF1A, TNFRSF1B, VAV1, XPA, DYRK2, CUL4A, CUL3, CUL2, CUL1, TNFRSF18, TNFRSF10D, ARHGEF7, BAG3, KIAA0141, ARHGEF11, CASP8AP2, PDCD6, RNF41 |
964 | GO:0001706 | 0.04 | 2.23 | 6.38 | 11 | 27 | endoderm formation | COL6A1, COL11A1, DUSP1, DUSP5, GATA4, GATA6, ITGA4, ITGA5, ITGAV, LAMA3, VTN |
965 | GO:0019731 | 0.04 | 2.23 | 6.38 | 11 | 27 | antibacterial humoral response | ANG, APP, KLK3, DMBT1, FAU, FGA, LTF, RPL39, SLPI, VIP, HIST2H2BE |
966 | GO:0032768 | 0.04 | 2.23 | 6.38 | 11 | 27 | regulation of monooxygenase activity | AGTR2, CALM3, CAV3, CNR1, DHFR, DNM2, PTK2B, FCER2, IFNG, INS, SNCA |
967 | GO:0034080 | 0.04 | 2.23 | 6.38 | 11 | 27 | CENP-A containing nucleosome assembly | CENPA, CENPI, HIST1H4I, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, RUVBL1 |
968 | GO:0061077 | 0.04 | 2.23 | 6.38 | 11 | 27 | chaperone-mediated protein folding | CANX, CLU, CSNK2A1, FKBP3, FKBP5, PPIB, PPID, PEX19, DNAJC7, FKBP6, TRAP1 |
969 | GO:0071230 | 0.04 | 2.23 | 6.38 | 11 | 27 | cellular response to amino acid stimulus | ASS1, BCL2L1, COL1A1, COL6A1, CYBA, DNMT1, DNMT3B, GLRA1, HMGCS2, IPO5, NTRK2 |
970 | GO:0045860 | 0.00 | 2.23 | 79.88 | 135 | 338 | positive regulation of protein kinase activity | ABL1, ACVR2B, ALK, ANG, ANGPT1, ARAF, BAX, BMP4, CALM3, CAMK2A, CCNC, CCNT2, CD4, CDKN1A, CENPE, CLU, CRKL, CSF1R, CSF2RB, CSPG4, ACE, DUSP5, LPAR1, EFNA1, EFNA5, EMP2, ERCC6, F2R, PTK2B, FGF3, FGF4, FGF7, FGFR3, FLT1, FLT3, FPR1, FYN, GCG, GNG3, GRB2, RAPGEF1, GRIN2A, GRM1, HGF, NRG1, IGF2, IL2RA, IL12B, ILK, INS, IRAK1, IRAK2, ITGA1, KIT, LTF, MARK3, KITLG, MAP3K11, NTRK3, P2RX7, PIM1, PPP5C, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTK2, PTPRA, RAF1, RASA2, RPS3, S100A12, CCL21, SDC4, SHC1, STIL, SNCA, STK10, ADAM17, TP73, TPD52L1, TRAF2, UBB, WNT11, FZD5, ARHGEF5, FGF23, FZD4, FZD8, CUL3, IKBKG, PDE5A, PEA15, RIPK1, RIPK2, TNFRSF10B, TNFRSF10A, UNC119, VAPB, ITGB1BP1, PSMF1, NRG2, TRAF4, RAPGEF2, SLK, ATG13, ZEB2, OXSR1, TNFSF15, RBX1, AKAP9, RASA4, PSME3, PSMD14 |
971 | GO:0001932 | 0.01 | 2.23 | 10.35 | 18 | 46 | regulation of protein phosphorylation | APLP2, APP, ARR3, CCNE1, CDC25A, CDC25C, CDK4, CKS1B, FGR, HRC, HRG, RAC2, RAD51, TSC1, UVRAG, IKBKAP, DIRAS3, EIF2AK3 |
972 | GO:0050778 | 0.01 | 2.22 | 11.59 | 20 | 50 | positive regulation of immune response | ANXA1, CNR1, FCER2, FFAR3, HRG, IFNG, IL13, IDO1, P2RX7, PTAFR, RARA, XCL1, STAT6, TRAF2, TNFSF4, UNG, FZD5, VAMP8, IL27RA, GAB2 |
973 | GO:0045785 | 0.00 | 2.22 | 33.32 | 57 | 142 | positive regulation of cell adhesion | ANGPT1, ANXA1, BAD, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD28, CD86, CD44, CD59, CD63, CTLA4, DPP4, EFNB1, EGR3, FLOT2, FYN, GRB2, NRG1, FOXA2, IFNG, IGF1, IGF2, IHH, IL2RA, IL12B, IL18, ITGA4, ITGAV, SMAD7, PRKCQ, PTAFR, PTPN6, RAG1, RAP1GAP, RARA, XCL1, CX3CL1, SELP, STAT5B, TRAF2, TNFSF4, VAV1, AP3B1, CHRD, TNFSF14, TNFSF9, RIPK2, TNFRSF18, AP3D1, TNFSF18, GRAP2, BAG4, PIEZO1 |
974 | GO:0045814 | 0.00 | 2.22 | 17.49 | 30 | 74 | negative regulation of gene expression, epigenetic | DNMT1, DNMT3B, ERCC3, HIST1H2AD, HMGA1, JARID2, PHF2, TBP, TTF1, HIST1H4I, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, HAT1, EED, SAP30, HIST1H3F, HIST1H2AG, TAF1B, TAF1A |
975 | GO:0002763 | 0.02 | 2.22 | 7.56 | 13 | 32 | positive regulation of myeloid leukocyte differentiation | ATP6AP1, CREB1, CSF1R, GNAS, HCLS1, IFNG, IL12B, JUN, KITLG, RB1, KLF10, OGT, RIPK1 |
976 | GO:0019748 | 0.02 | 2.22 | 7.56 | 13 | 32 | secondary metabolic process | ARL1, ASIP, AKR1C4, CTNS, CYP2A6, CYP11B1, PAM, PGAM1, TRPC1, TYR, AKR1C3, RAPGEF2, ZEB2 |
977 | GO:0032481 | 0.02 | 2.22 | 7.56 | 13 | 32 | positive regulation of type I interferon production | CHUK, EP300, IFI16, IRAK1, IRF1, IRF5, TRIM21, STAT6, UBB, XRCC5, IKBKG, RIPK1, RIPK2 |
978 | GO:0034162 | 0.02 | 2.22 | 7.56 | 13 | 32 | toll-like receptor 9 signaling pathway | CHUK, CREB1, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, RPS6KA1, SKP1, UBB, CUL1, IKBKG, RIPK2 |
979 | GO:0035019 | 0.02 | 2.22 | 7.56 | 13 | 32 | somatic stem cell population maintenance | ASCL2, ZFP36L2, CDX2, FGFR3, RBPJ, KIT, RAF1, SALL1, SOX9, STAT3, KLF10, CUL4A, KLF4 |
980 | GO:0050764 | 0.02 | 2.22 | 7.56 | 13 | 32 | regulation of phagocytosis | BCR, BLK, C3, CD36, CYBA, DNM2, FGR, ITGAV, PTEN, RAB27A, RAP1GAP, SFTPD, TULP1 |
981 | GO:0071479 | 0.02 | 2.22 | 7.56 | 13 | 32 | cellular response to ionizing radiation | ATR, BCL2L1, CDKN1A, CYBA, DNM2, ELK1, GRB2, IFI16, ITGB1, MGMT, RAD51, XRCC5, CLOCK |
982 | GO:2001244 | 0.02 | 2.22 | 7.56 | 13 | 32 | positive regulation of intrinsic apoptotic signaling pathway | BAD, BAX, BCL2L1, CLU, RPS3, S100A8, S100A9, SFPQ, TP73, UBB, SLC9A3R1, EIF2AK3, BCL2L11 |
983 | GO:0097696 | 0.01 | 2.22 | 11.05 | 19 | 47 | STAT cascade | CHAD, CSH1, DCN, GH2, GP1BA, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, PPP2R1A, PTPN6, STAT2, STAT3, STAT4, STAT5B, ADAM17, SOCS3, SOCS6 |
984 | GO:0090090 | 0.00 | 2.22 | 19.85 | 34 | 84 | negative regulation of canonical Wnt signaling pathway | RAPGEF1, IGFBP6, ISL1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, SFRP5, SOX9, SOX10, UBB, WNT11, FZD6, CUL3, RGS20, LATS1, PSMF1, RBX1, G3BP1, PSME3, PSMD14 |
985 | GO:0007569 | 0.02 | 2.22 | 8.73 | 15 | 37 | cell aging | ARNTL, ATR, BGLAP, BMPR1A, BRCA2, CDKN1A, CHEK1, HMGA1, ICAM1, ILK, ING2, OPA1, SERPINE1, SRF, NUAK1 |
986 | GO:0045931 | 0.01 | 2.21 | 9.90 | 17 | 42 | positive regulation of mitotic cell cycle | ABL1, ANXA1, APP, BRCA2, CCNB1, CDK4, EIF4E, RAD51C, RAD51B, RPS6KB1, SMARCD3, STAT5B, TAL1, UBE2E2, CUL4A, PHOX2B, USP2 |
987 | GO:0032868 | 0.05 | 2.21 | 5.80 | 10 | 25 | response to insulin | CAT, EGR2, IL10, INPPL1, PCK1, PLN, PTPRN, SORT1, STXBP3, EPM2AIP1 |
988 | GO:0019083 | 0.00 | 2.21 | 24.58 | 42 | 104 | viral transcription | EP300, ERCC3, FAU, JUN, NUP98, RANBP2, REST, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, SMARCA4, SP1, SP100, TRIM21, SSRP1, USF1, NUP214, AAAS, RPL14, CTDP1, RPL23, NUP155, NUP93 |
989 | GO:0006970 | 0.02 | 2.21 | 8.74 | 15 | 37 | response to osmotic stress | BAX, TSPO, TSC22D3, PTK2B, HNMT, PCP4, RAC1, SCN2A, SLC2A4, SLC12A1, SORD, TACR3, ARHGEF2, OXSR1, SLC12A6 |
990 | GO:0043067 | 0.00 | 2.21 | 186.93 | 306 | 792 | regulation of programmed cell death | ABL1, ABL2, ACTN1, ADAR, AGTR2, ALB, ALDH1A3, ALK, ALX3, ANGPT1, ANXA1, ANXA5, APAF1, BIRC3, XIAP, BIRC5, APOH, ARAF, ARHGAP4, ASCL1, ATF4, AXL, BARD1, BAX, BCL2A1, BCL3, BLK, BMP1, BMP3, BMP4, BMP8B, BNIP3L, BOK, BTK, TSPO, CACNA1A, CAMK2A, CASP5, CASP9, CAT, CBL, KRIT1, CD3E, CD3G, TNFRSF8, CD44, CD59, CDK4, CDKN1A, CLU, CNR1, COL4A3, COMP, CREB1, CRYBA1, CSF1R, CSNK2A1, CTGF, CTH, CTLA4, CTNNA1, CTSH, CX3CR1, DAD1, DAPK3, DBH, DFFA, DNM2, DPEP1, TSC22D3, DUSP1, LPAR1, EDNRA, EGR3, CTTN, ERCC3, ETS1, F2R, F3, PTK2B, FAP, FGA, FGD1, FGF4, FGFR3, FLT3, FLT4, FYN, GABRA5, GAS1, GATA6, GCG, GDF9, B4GALT1, GPLD1, GPX1, GRID2, GRIN2A, GRINA, HCLS1, HGF, NRG1, HIP1, HMGCR, HRG, HSPA9, HSPB1, ICAM1, IFIT3, IFNG, IGF1, IGF1R, IGFBP3, IHH, IL1A, IL10, IL12B, IL13, ILK, IDO1, ING2, INHA, INS, IRAK1, IRF5, ISL1, ITGA1, ITGA5, ITGAV, ITGB1, JUN, KCNJ1, KDR, KIT, KNG1, LTF, SMAD3, SMAD6, MAL, KITLG, MGMT, MAP3K11, YBX1, NTF4, NTRK2, NTRK3, NTSR1, OPA1, P2RX1, P2RX7, PA2G4, SERPINE1, PCP4, PDK4, SERPINB13, PIM1, PPID, PPP2R1A, PPP2R1B, PRKAA1, PRKCI, PRKCQ, PROC, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTGIS, PTK2, PTN, RAC1, RAF1, RAG1, RARA, RARB, REST, RPS3, RPS3A, RPS6, RPS6KA1, RPS6KB1, RXRA, SORT1, S100A8, S100A9, CCL21, CX3CL1, SET, SFPQ, SGK1, STIL, SLC9A1, SNAI1, SNCB, SNCA, SOD2, SOS2, SOX9, SOX10, SP100, SRPK2, STAT3, STAT5B, STK10, SUPV3L1, ADAM17, TNFRSF1A, TNFRSF1B, TOP2A, TP73, TPD52L1, TPT1, HSP90B1, TRAF1, TRAF2, TYRO3, UBB, UNG, VAV1, VDAC2, VEGFB, VIL1, VIP, TRPV1, WFS1, WNT1, WNT11, XRCC2, YWHAZ, ZNF16, SCG2, FOSL1, NSMAF, KLF11, API5, TP63, UNC5C, AKR1C3, DYNLL1, PEA15, TRADD, RIPK1, CRADD, HRK, TNFSF14, TNFSF10, RIPK2, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, NRP1, ARHGEF7, TAX1BP1, TNFSF18, SOCS3, RGN, LATS1, ARHGEF2, AURKB, STK17B, STK17A, KLF4, SLIT2, SLC9A3R1, EIF2AK3, ATG5, PSMF1, GDF15, BAG5, BAG4, BAG3, BCAR1, TRAF4, RAPGEF2, SLK, KIAA0141, RB1CC1, ARHGEF11, OXSR1, TNFSF15, NR1H4, CASP8AP2, HDAC6, PDCD6, PDCD7, SGK2, FEM1B, TRAP1, PSME3, DHRS2, PSMD14 |
991 | GO:0035725 | 0.01 | 2.21 | 11.08 | 19 | 47 | sodium ion transmembrane transport | ATP1A1, ATP1A3, ATP12A, ATP4A, SCN1A, SCN2A, SCN7A, SCN8A, SCNN1A, SCNN1B, SCNN1G, SLC8A3, SLC9A2, SLC9A3, SLC13A1, SLC20A1, TRPM2, SLC4A7, HCN4 |
992 | GO:0010959 | 0.02 | 2.21 | 8.14 | 14 | 35 | regulation of metal ion transport | ATF4, CD63, DPP6, KCNC2, KCNH2, KCNJ1, KCNJ2, KCNQ1, KCNS2, VIP, KCNAB1, AKAP7, OXSR1, AKAP9 |
993 | GO:0006955 | 0.00 | 2.21 | 28.45 | 49 | 127 | immune response | ARHGDIB, TNFRSF17, BMPR1A, BPI, CD1B, CD7, TNFRSF8, TNFSF8, CD70, ADGRE5, CCR8, CYP11B1, EDA, EMP2, ETS1, CXCL3, GZMH, IGF1R, IK, IL1R1, IL18, ITGAD, SMAD6, PF4V1, PRG2, RAG1, RFX1, CXCL6, CXCL5, ADAM17, TNFRSF1A, TNFRSF1B, IL1R2, IKBKAP, S1PR4, TNFSF14, TNFSF10, TNFSF9, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, CXCL14, GTPBP1, TNFSF15, IL18BP, COL4A3BP, CHST4, PRG4 |
994 | GO:1901568 | 0.01 | 2.21 | 9.93 | 17 | 42 | fatty acid derivative metabolic process | ALOX15B, ANXA1, DAGLA, CBR1, CYP2A6, CYP2A13, CYP2F1, DPEP1, FAAH, GGT7, GPX1, HPGD, LTA4H, PTGIS, PTGS1, TNFRSF1A, AKR1C3 |
995 | GO:0046034 | 0.00 | 2.21 | 13.44 | 23 | 57 | ATP metabolic process | AK1, AK2, AMPD2, ATP1A2, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1B2, ATP6V0A1, BAD, COX8A, COX15, CTNS, LDHC, SDHC, TAZ, UQCRC1, UQCRC2, UQCRH, SLC25A13 |
996 | GO:0006073 | 0.01 | 2.20 | 11.11 | 19 | 47 | cellular glucan metabolic process | ADRA1B, CALM3, CPS1, G6PC, GAA, GCGR, GYS2, IGF1, IGF2, INS, PHKA2, PHKB, PHKG1, PYGB, PYGM, UBB, DYRK2, MGAM, EPM2AIP1 |
997 | GO:0046883 | 0.00 | 2.20 | 34.71 | 59 | 147 | regulation of hormone secretion | ABAT, ANXA1, ANXA5, ARL2, ARNTL, BAD, BLK, CACNA1A, CHRM3, CNR1, CREB1, CRHBP, EFNA5, EPHA5, FGA, GALR1, GCG, GDF9, GHRHR, GHSR, GLUD1, GNAS, GPLD1, FFAR1, FFAR3, HMGCR, FOXA2, HTR2C, IFNG, INS, ISL1, ITPR1, KCNC2, KCNJ11, KCNS3, OXCT1, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PTGS1, REST, RFX3, SNAP25, SOX11, SREBF1, SYT5, TRPM2, FGF23, VAMP8, ARHGEF7, SYT7, HMGN3, NRXN1, CLOCK, NR1H4 |
998 | GO:0009124 | 0.00 | 2.20 | 13.47 | 23 | 57 | nucleoside monophosphate biosynthetic process | ADSS, AK1, AK2, AMPD1, AMPD2, APRT, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, HPRT1, IMPDH1, IMPDH2, LDHC, PFAS, SHMT1, STAT3, TYMS, UPP1, SLC25A13 |
999 | GO:0046364 | 0.00 | 2.20 | 13.47 | 23 | 57 | monosaccharide biosynthetic process | ALDOC, ATF4, ENO2, G6PC, GAPDH, GCG, KAT2A, GOT2, GPD2, INS, MDH2, PCK1, PCK2, PGAM1, PRKACB, PRKACG, RANBP2, SORD, OGT, SLC25A12, RGN, GSTO1, SLC25A13 |
1000 | GO:0006952 | 0.00 | 2.20 | 16.77 | 29 | 76 | defense response | ANXA3, KLK3, BCL3, BNIP3L, BPI, CD8A, TNFSF8, CEBPE, CXADR, DBI, DPP4, EIF4E, HRG, HTR2C, IFNW1, KCNJ8, KCNN4, P2RY11, PRG2, PSG3, RAB1A, RNASE6, RPS6KB1, ADAM17, TPSAB1, SOCS6, IL27RA, ADAMTS4, ABCC9 |
1001 | GO:0007603 | 0.00 | 2.20 | 14.65 | 25 | 62 | phototransduction, visible light | ABCA4, OPN1SW, CALM3, AKR1C4, CHRM1, CLPS, CNGA1, GPC4, OPN1MW, GPC3, GNAQ, GNAT1, GNGT1, GUCA1A, GUCY2F, GUCY2D, PRKCQ, RBP1, RBP2, OPN1LW, RCVRN, SDC4, AKR1C3, GUCA1C, SDC3 |
1002 | GO:0002366 | 0.00 | 2.20 | 26.47 | 45 | 112 | leukocyte activation involved in immune response | ABL1, ANXA1, ANXA3, BCL3, BCR, CD28, CD86, CX3CR1, PTK2B, FGR, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IL10, IL12B, IL13, IL13RA2, KIT, PRKCE, PTAFR, RAB27A, RAC2, RARA, S100A13, STAT6, STXBP2, STXBP3, TSC1, TNFSF4, TYROBP, UNG, LAT2, VAMP8, STX11, RIPK2, TNFSF18, RNF8, EXO1, IL27RA, GAB2 |
1003 | GO:1902600 | 0.00 | 2.19 | 18.20 | 31 | 77 | hydrogen ion transmembrane transport | ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP4A, ATP4B, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, COX6A1, COX6B1, COX7A1, COX7C, COX8A, COX15, CYB5A, SLC9A1, SLC9A2, SLC9A3, UQCRC1, UQCRH, ATP6V0D1, ATP6V1G1 |
1004 | GO:0071216 | 0.00 | 2.19 | 22.92 | 39 | 97 | cellular response to biotic stimulus | ABCA1, ABL1, APAF1, ARG1, ASS1, AXL, PRDM1, BYSL, TSPO, CD6, CD86, CD36, ENTPD2, CEBPE, CX3CR1, HMGCS2, ICAM1, IFNG, IL10, IL12B, IL18, IRAK1, IRAK2, LTF, P2RY2, SERPINE1, PDE4B, PRKCE, PTAFR, RARA, UPF1, TNFRSF1B, TNFSF4, WFS1, FZD5, OGT, RIPK2, EIF2AK3, LITAF |
1005 | GO:0023056 | 0.00 | 2.19 | 16.24 | 28 | 73 | positive regulation of signaling | BLK, CHRNB2, CHRNB4, CREB1, CRH, CX3CR1, DBI, DNM1, GALR1, GFAP, GLUD1, GPLD1, FFAR1, OXCT1, OXTR, PTN, RAB3B, SLC8A3, SNAP25, SNCA, STAU1, SYT1, TNR, TRPM2, VAMP8, SYNJ1, ARHGEF7, RAMP3 |
1006 | GO:0051924 | 0.01 | 2.19 | 9.35 | 16 | 40 | regulation of calcium ion transport | CACNA1B, CACNB4, CASQ1, CYBA, DIAPH1, PTK2B, HRC, IGF1, P2RX1, PDE4B, PRKCE, PRKD1, PTPN6, RCVRN, TRPC4, ATG5 |
1007 | GO:0007420 | 0.00 | 2.19 | 32.29 | 55 | 140 | brain development | ABAT, ABL1, ABL2, AGTR2, AK2, ARCN1, RERE, ATP2B1, ATP2B2, BCR, BMPR2, BOK, BRCA2, BYSL, CACNA1A, CD9, CENPF, CLN5, CTNS, DNMT1, S1PR1, EGR2, EML1, AFF2, GABRA5, GRID2, HMGCS2, HMX2, FOXA2, HNMT, IGF1, IGF1R, ITGB1, KCNK3, OXCT1, SMARCA1, STXBP3, SYT1, SYT4, NR2C2, TULP3, UBE3A, ZIC1, KCNAB1, FZD4, ATRN, UNC5C, PHOX2B, ATP6V0D1, NRXN1, SLC4A7, BAG3, AATK, BCL2L11, ABCB6 |
1008 | GO:0007596 | 0.00 | 2.19 | 39.46 | 67 | 170 | blood coagulation | ABL1, ANGPT1, ANGPT2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, BSG, C3, CD44, CD58, CD59, CDK2, CENPE, CXADR, F10, FBLN1, FGR, GATA4, GATA6, GRB7, HBD, HBE1, FOXA2, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IRF1, ITGA1, ITGA4, ITGA5, ITGAM, ITGAV, ITGB1, KIF5A, OLR1, SERPINA5, PRCP, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, RAB5A, RAB27A, RAD51C, RAD51B, SELE, SELL, SELPLG, SLC8A3, SLC7A5, AKAP1, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, AP3B1, PDE5A, PROZ, HIST1H3F, DOK2, KIF3B, KCNMB2 |
1009 | GO:0009611 | 0.00 | 2.19 | 93.36 | 156 | 402 | response to wounding | ABL1, ACTB, ACTN1, ACVRL1, ALB, ANGPT1, ANGPT2, BIRC3, XIAP, APP, ATP2A1, ATP2B1, ATP2B2, ATP2B3, AXL, BMP4, DST, BSG, C7, DAGLA, CALM3, CASP5, CAV3, CCNB1, CD9, ENTPD2, CD44, CD58, CD59, CD63, CDK2, CENPE, CLU, COL1A1, CSRP1, CTGF, CXADR, DGKB, DCN, DRD5, F2RL2, F10, FBLN1, FGF7, FGR, FYN, GATA4, GATA6, GFAP, B4GALT1, GNA15, GNAI1, GNAQ, GNAS, GP9, GRB2, GRB7, GRIN2A, HBD, HBE1, HGF, NRG1, FOXA2, HSPB1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IGF1, IGF2, IL1A, IL1R1, ILK, IRF1, ITGA1, ITGA4, ITGA5, ITGA9, ITGAM, ITGAV, ITGB1, ITPR1, KIF5A, LAMP2, OLR1, P2RX1, P2RY2, SERPINA5, PF4V1, CFP, PRCP, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCQ, PSAP, PSMA6, PTK2, PTPN6, RAB5A, RAB27A, RAC1, RAC2, RAD51C, RAD51B, RAF1, RAP2B, RPS6KB1, SCNN1B, SDC4, SELE, SELL, SELPLG, SRSF5, SHC1, SLC8A3, SPARC, SPRR3, SRF, STXBP3, ADAM17, TRPC3, TUBA4A, SCGB1A1, VAV1, VIL1, WNT1, YWHAZ, SLC7A5, AKAP1, DYSF, FZD6, FZD7, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, AP3B1, PDE5A, ADAM15, NRP1, PROZ, HIST1H3F, DOK2, SYT7, DGKI, KIF3B, BCAR1, GNA14, NR1D2, KCNMB2, ABCC4 |
1010 | GO:0035270 | 0.05 | 2.18 | 5.86 | 10 | 25 | endocrine system development | ASCL1, TSPO, CRH, CRKL, HHEX, SMAD3, RAF1, RAP1GAP, SRF, WNT11 |
1011 | GO:0071103 | 0.02 | 2.18 | 8.21 | 14 | 35 | DNA conformation change | ANXA1, CHD2, CHD4, DDX1, HHEX, PURA, RAD51, SUPV3L1, XRCC5, RECQL5, CHD1L, GINS1, RAD50, G3BP1 |
1012 | GO:0051701 | 0.00 | 2.18 | 28.36 | 48 | 120 | interaction with host | ALB, AXL, BAD, BCL2L1, CD4, CD86, SCARB2, CR2, CXADR, DPP4, EPS15, FBLN1, GYPA, ICAM1, IFIT1, IFNA2, ITGA5, ITGAV, ITGB1, KPNA1, KPNA2, KPNA3, KPNA4, LTF, SMAD3, NTRK3, NUP98, SERPINB9, PVR, RANBP2, RXRA, SELPLG, SLC10A1, SLC22A5, TRIM21, DYNLT1, TYMS, TYRO3, UVRAG, TRIM25, NUP214, AAAS, VAMP8, CLDN1, VAPB, NUP155, NUP93, BCL2L11 |
1013 | GO:0050796 | 0.00 | 2.18 | 18.85 | 32 | 80 | regulation of insulin secretion | ABAT, ARL2, ARNTL, BLK, CACNA1A, CHRM3, CNR1, GHSR, GLUD1, GNAS, FFAR1, IFNG, INS, ISL1, ITPR1, KCNC2, KCNJ11, KCNS3, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, REST, RFX3, SNAP25, SREBF1, SYT5, TRPM2, SYT7, CLOCK |
1014 | GO:0042742 | 0.01 | 2.18 | 10.58 | 18 | 45 | defense response to bacterium | ANXA3, BCL3, CEBPE, CYBA, HP, IFNG, RBPJ, IL10, CFP, PRG2, RAB1A, S100A8, S100A9, S100A12, CXCL6, SFTPD, TNFRSF1A, ADAMTS4 |
1015 | GO:0050867 | 0.00 | 2.17 | 34.98 | 59 | 148 | positive regulation of cell activation | ANXA1, AXL, BAD, PRDM1, BTK, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD28, CD86, CD59, CDKN1A, CHRNB2, CTGF, CTLA4, DPP4, EFNB1, EGR3, FGR, FLOT2, FLT3LG, FYN, GRB2, IFNG, IGF1, IGF2, IHH, IL2RA, IL12B, IL13, IL18, PRKCQ, PTAFR, PTPN6, RAC1, RAG1, RARA, RPS6KA1, CCL21, XCL1, SELP, STAT5B, STAT6, TRAF2, TNFSF4, UNG, VAV1, AP3B1, VAMP8, TNFSF14, TNFSF9, RIPK2, AP3D1, IL1RL1, GRAP2, GAB2 |
1016 | GO:0009612 | 0.00 | 2.17 | 17.09 | 29 | 73 | response to mechanical stimulus | ANGPT2, ATP2B2, BGLAP, CCNB1, ENTPD2, CLCN6, COL11A1, DCN, ETS1, F3, PTK2B, FYN, GATA4, IGF1, JUND, KCNA1, KCNK2, KIT, NTRK2, P2RX3, P2RX7, PSPH, RPS6KB1, SLC12A2, XPA, FOSL1, NRXN1, NRXN2, PIEZO1 |
1017 | GO:0071456 | 0.00 | 2.17 | 12.97 | 22 | 55 | cellular response to hypoxia | BAD, BNIP3L, CCNB1, CLCA1, GATA6, GNGT1, ICAM1, IRAK1, KCND2, KCNK2, KCNK3, PRKAA1, PRKCE, PTEN, PTGIS, PTN, SLC2A4, SLC8A3, SLC9A1, STC1, TRPC1, OGT |
1018 | GO:0048839 | 0.02 | 2.17 | 9.43 | 16 | 40 | inner ear development | BMP4, FGFR3, GABRA5, IGF1, RBPJ, KCNK2, KCNK3, KCNQ1, NTRK3, SDC4, SPARC, LIN7A, PHOX2B, ATG5, SLC4A7, CXCL14 |
1019 | GO:0043010 | 0.00 | 2.17 | 19.48 | 33 | 83 | camera-type eye development | ALDH1A3, AQP5, CDK2, CDK4, CRYBA1, CRYBA4, CRYGB, CTNS, EPHA2, FBN1, EFEMP1, FGFR3, GPD2, HMGN1, HSF4, JUN, KDR, LIM2, SMAD3, NTRK3, RARA, RCN1, RXRA, SOX11, SP1, SRF, TULP3, VIM, YY1, FZD5, BCAR3, KLF4, ZEB2 |
1020 | GO:0043408 | 0.00 | 2.17 | 99.02 | 164 | 419 | regulation of MAPK cascade | ABL1, ABL2, ADRA1B, ALK, ANGPT1, ARAF, ATP6AP1, BMP1, BMP3, BMP4, BMP8B, C3, CALM3, CAMK2A, CAV3, CD36, CD44, CRKL, CRYBA1, CSF1R, CSF2RB, CSPG4, CTGF, DUSP1, DUSP5, LPAR1, EDNRA, EFNA1, EPHA2, EPHA8, EPHB1, ERCC6, F2R, PTK2B, FBLN1, FGA, FGF3, FGF4, FGF7, FGFR3, FLT1, FLT3, FLT4, FPR1, FSHR, FYN, GCG, GDF9, GNG3, GRB2, RAPGEF1, GRIN2A, GRM1, HGF, NRG1, HMGCR, HTR2C, ICAM1, IGF1, IGF1R, IGF2, IGFBP3, IL1A, IL2RA, ILK, INHA, INS, IRAK1, IRAK2, ITGA1, ITGB1, JUN, KDR, KISS1, KIT, MARK3, KITLG, MAP3K11, NTRK2, NTRK3, P2RX7, PRDX1, PPP2R1A, PPP5C, PRKAA1, PRKCE, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, PTPN6, PTPRA, PTPRJ, PTPRR, RAF1, RAP2A, RASA2, RPS3, RYK, S100A7, S100A12, CCL21, CCL22, CCL25, XCL1, CX3CL1, SHC1, STYX, XCL2, TNFRSF1B, TP73, TPD52L1, TRAF2, TSG101, UBB, VEGFB, FZD5, ARHGEF5, FGF23, FZD4, FZD7, FZD8, CUL3, IKBKG, PDE5A, PEA15, RIPK1, RIPK2, NRP1, ITGB1BP1, GPR55, KLF4, SLC9A3R1, PSMF1, GDF15, NRG2, TRAF4, RAPGEF2, ZEB2, RBX1, RANBP9, AKAP9, RASA4, ATP6AP2, RNF41, PSME3, PSMD14, SPRY1 |
1021 | GO:0035051 | 0.03 | 2.17 | 7.07 | 12 | 30 | cardiocyte differentiation | GATA6, KAT2A, NRG1, RBPJ, ISL1, ITGB1, RARA, RARB, REST, RXRA, SLC9A1, TSC1 |
1022 | GO:0098792 | 0.00 | 2.17 | 13.00 | 22 | 55 | xenophagy | ANXA5, COX8A, FGF7, GABRA5, KCNQ1, NTHL1, PDK4, PEX13, SCN1A, SNRPD1, STAT2, ZNF189, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H3F, CHST3, NUP93, PHYHIP, FGFBP1 |
1023 | GO:0002286 | 0.01 | 2.17 | 11.82 | 20 | 50 | T cell activation involved in immune response | ANXA1, BCL3, CD86, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IL12B, RAB27A, RARA, STAT6, TSC1, TNFSF4, STX11, RIPK2, TNFSF18 |
1024 | GO:0008286 | 0.00 | 2.16 | 48.92 | 82 | 207 | insulin receptor signaling pathway | ANGPT1, ARAF, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, CALM3, CAMK2A, CSF2RB, DUSP5, EIF4E, FGF3, FGF4, FGF7, FGFR3, FYN, GPLD1, GRB2, GRIN2A, NRG1, IGF1R, IGF2, IL2RA, INS, KIT, MARK3, KITLG, FOXO4, YBX1, PDK4, PPP5C, PRKAA1, PRKAG1, PRKCQ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTK2, PTPRA, PTPRE, RAF1, RASA2, RHEB, RPS6, RPS6KB1, SHC1, SREBF1, TSC1, UBB, FGF23, CUL3, OGT, PIK3R3, PEA15, SOCS3, ATP6V0D1, PSMF1, NRG2, ATP6V1G1, BCAR1, RAPGEF2, C2CD5, RBX1, AKAP9, RASA4, PSME3, PSMD14 |
1025 | GO:0010043 | 0.03 | 2.16 | 7.08 | 12 | 30 | response to zinc ion | ALAD, ARG1, ASS1, BGLAP, CPS1, HMBS, LTA4H, P2RX7, PLN, PTEN, S100A8, SLC30A2 |
1026 | GO:0002027 | 0.01 | 2.16 | 10.63 | 18 | 45 | regulation of heart rate | ADRA1B, AGTR2, CALM3, CASQ2, CAV3, HRC, KCNH2, KCNJ2, KCNQ1, PLN, RYR2, SCN4B, SCN5A, SREBF1, TACR3, HCN4, AKAP9, IRX5 |
1027 | GO:0033077 | 0.01 | 2.16 | 10.63 | 18 | 45 | T cell differentiation in thymus | BMP4, ZFP36L2, CD3D, CD3E, CD28, CDK6, EGR3, IHH, RAG1, RAG2, SOS2, SRF, STAT5B, ADAM17, WNT1, FZD5, FZD7, FZD8 |
1028 | GO:0044784 | 0.01 | 2.16 | 10.63 | 18 | 45 | metaphase/anaphase transition of cell cycle | BUB1B, CCNB1, CDC20, CDC27, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, PTEN, RB1, TTK, ZNF207, CUL3, CDC23, CDC16, ZW10, DLGAP5 |
1029 | GO:0019054 | 0.02 | 2.16 | 9.45 | 16 | 40 | modulation by virus of host process | BAD, BCL2L1, CD4, KPNA1, KPNA2, KPNA3, KPNA4, NTRK3, NUP98, RANBP2, NUP214, AAAS, VAPB, NUP155, NUP93, BCL2L11 |
1030 | GO:0034644 | 0.02 | 2.16 | 9.45 | 16 | 40 | cellular response to UV | ATF4, ATR, BAX, CASP9, CDC25A, CDKN1A, CHEK1, EP300, ERCC4, PCNA, PPID, PTN, TP73, YY1, TP63, AURKB |
1031 | GO:0032410 | 0.02 | 2.16 | 8.27 | 14 | 35 | negative regulation of transporter activity | ATP1A2, CALM3, CASQ2, CAV3, DRD3, KCNQ1, PLN, PRKCE, SNCA, SUMO1, KCNAB1, SLC9A3R1, GSTO1, OXSR1 |
1032 | GO:0010942 | 0.00 | 2.16 | 72.01 | 120 | 306 | positive regulation of cell death | AGTR2, ALDH1A3, ANXA1, ANXA5, APAF1, ARHGAP4, BARD1, BCL2A1, BCL2L1, BMP4, BNIP3L, BOK, TSPO, CAMK2A, TNFRSF8, CDK4, CDKN1A, CNR1, COL4A3, CREB1, CRH, CRYBA1, CTGF, CTLA4, CTNNA1, CTSH, DAPK3, DFFA, DNM2, DUSP1, LPAR1, ERCC3, F2R, F3, FAP, FGD1, B4GALT1, GPLD1, GRIN2A, HBA2, HIP1, HMGCR, HP, HRG, IFNG, IGFBP3, IL10, IL12B, IDO1, ING2, IRF5, ITGB1, KCNK2, KNG1, SMAD3, MAL, NTRK3, NTSR1, P2RX1, P2RX7, PPID, PPP2R1A, PPP2R1B, PRKCI, PTEN, PTGIS, PTN, RAC1, RARB, REST, RPS3, RPS6, RXRA, SORT1, S100A8, S100A9, SFPQ, SLC9A1, SNCA, SOS2, TOP2A, TP73, TPD52L1, TRAF2, UBB, VAV1, TRPV1, WNT11, YWHAZ, FOSL1, NSMAF, KLF11, TP63, UNC5C, AKR1C3, DYNLL1, PEA15, TRADD, RIPK1, CRADD, HRK, TNFSF10, RIPK2, TNFRSF10B, TNFRSF10A, ARHGEF7, LATS1, ARHGEF2, STK17B, STK17A, SLIT2, SLC9A3R1, EIF2AK3, RAPGEF2, ARHGEF11, TNFSF15, CASP8AP2, HDAC6, PDCD6, PDCD7 |
1033 | GO:0007405 | 0.03 | 2.16 | 7.09 | 12 | 30 | neuroblast proliferation | ASCL1, DAGLA, CTNNA1, CX3CR1, EML1, KCNA1, CX3CL1, SIX3, SMARCD3, SOX10, FZD9, NUMB |
1034 | GO:0030512 | 0.03 | 2.16 | 7.09 | 12 | 30 | negative regulation of transforming growth factor beta receptor signaling pathway | DNM2, FBN1, ONECUT1, SMAD3, SMAD6, SMAD7, ADAM17, UBB, WNT1, ZFYVE9, ONECUT2, ADAMTSL2 |
1035 | GO:0050772 | 0.03 | 2.16 | 7.09 | 12 | 30 | positive regulation of axonogenesis | BMPR2, EFNA5, GOLGA4, NRG1, ILK, LIMK1, NTRK2, NTRK3, SRF, RND2, NRP1, SLIT2 |
1036 | GO:0055006 | 0.03 | 2.16 | 7.09 | 12 | 30 | cardiac cell development | AGTR2, BMP4, CAV3, CCNB1, CXADR, GATA4, SGCB, SRF, SORBS2, CTDP1, AKAP6, ATG5 |
1037 | GO:0070830 | 0.03 | 2.16 | 7.09 | 12 | 30 | bicellular tight junction assembly | ARL2, CLDN3, ITGB1, PRKCI, SNAI1, SRF, STRN, TBCD, WNT11, FZD5, CLDN12, CLDN1 |
1038 | GO:0097006 | 0.03 | 2.16 | 7.09 | 12 | 30 | regulation of plasma lipoprotein particle levels | ABCA1, AGTR1, ARF1, CD36, GPLD1, LCAT, LIPC, LRPAP1, NR1H2, DGAT1, LIPG, NR1H4 |
1039 | GO:1902305 | 0.03 | 2.16 | 7.09 | 12 | 30 | regulation of sodium ion transmembrane transport | ARF1, ATP1A2, FXYD2, CAV3, DNM2, DRD3, FXYD3, PRKCE, SCN4B, SCN5A, SLC9A1, SLC9A3R1 |
1040 | GO:0050900 | 0.00 | 2.16 | 17.74 | 30 | 76 | leukocyte migration | ANGPT1, ANGPT2, BCR, BSG, CD44, CD58, COL1A1, DBH, ECM1, S1PR1, F2, FYN, B4GALT1, GPR15, GRB2, GRB7, IL10, ITGA5, ITGAM, ITGAV, ITGB1, OLR1, PROC, PTPN6, SELL, SELPLG, SHC1, STK10, SLC7A5, DOK2 |
1041 | GO:0044419 | 0.00 | 2.16 | 91.08 | 151 | 389 | interspecies interaction between organisms | ADAR, TRIM23, ARF1, BAX, BICD1, BNIP3L, BST2, CCNT2, CD28, CD36, CDC25C, CENPA, AP1S1, AP2S1, CCR3, CREB1, CX3CR1, DDX5, DDX6, DMBT1, E4F1, EPHA2, EIF4A1, EIF4E, EP300, ERCC3, FAU, FDPS, NR5A2, FYN, KAT2A, GPX1, GRB2, HMGA1, HPX, IFI16, SP110, IFNG, IL10, IL12B, ISG20, JUN, KDR, IPO5, OAS3, OSBP, CHMP1A, PCSK5, PPIB, PPID, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, RAB1A, RAB6A, RAC1, RALA, RAN, RANBP1, RB1, REST, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, SATB1, SET, SHC1, SKP1, SLPI, SMARCA4, SP1, SP100, SRPK2, SSRP1, STAT2, STAT3, STAU1, TAF4B, TAF10, TBP, TSPAN7, TNFRSF1A, TOP1, TOP2A, TP73, TSG101, UBB, UBE3A, SUMO1, UNG, USF1, VIM, EIF4H, XRCC5, CUL4A, CUL2, CUL1, IKBKG, DYNLL1, EIF4G3, AP1M1, RPL14, CLDN6, CTDP1, RPL23, RAB9A, ATG5, PSMF1, KDM4A, CUL7, RBX1, PDCD6IP, AP1M2, RAD50, ABI2, WASF2, PSME3, PSMD14 |
1042 | GO:0060348 | 0.00 | 2.16 | 23.16 | 39 | 98 | bone development | ATP6AP1, BGLAP, BMP4, BMPR2, RUNX2, CHAD, COL1A1, COL9A1, COMP, DLX5, EP300, FGF4, FGFR3, GNAS, IGF1, INPPL1, INSIG1, KIT, LTF, SMAD1, SMAD9, PEX7, PIP4K2A, PPIB, PTPN6, RARA, RARB, RYR1, SOX9, SPARC, SRD5A1, SRF, STC1, TAL1, TULP3, TYROBP, WNT1, RGN, WASF2 |
1043 | GO:0060537 | 0.00 | 2.15 | 29.16 | 49 | 124 | muscle tissue development | AGTR2, KLF5, CASQ1, COL11A1, CSF1R, DCN, S1PR1, EGR2, EP300, EYA2, KAT2A, GPX1, HLF, HOXD9, HOXD10, IHH, ISL1, ITGB1, SMAD1, SMAD7, MEOX2, PLN, PRKAR1A, PTEN, RARA, RARB, RB1, RXRA, RYR1, RYR2, SGCB, SLC9A1, SOX9, SOX11, SRF, TAZ, NR2F2, TNNC1, TNNI3, TSC1, KCNAB1, SORBS2, TP63, SAP30, PHOX2B, COPS2, GTF3C5, HAND1, ATG5 |
1044 | GO:0002521 | 0.00 | 2.15 | 41.81 | 70 | 178 | leukocyte differentiation | ABL1, ABL2, BAX, BCL3, BGLAP, BMP4, ZFP36L2, RUNX2, CD3D, CD3E, CD4, CD8A, CD28, TNFSF8, CDK6, CEBPE, CHUK, CR2, CTLA4, EPHA2, EP300, PTK2B, FLT3, FSHB, FSHR, GPC3, HHEX, ONECUT1, IFI16, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, RBPJ, IL10, INHA, IRF1, ITGA4, ITGB1, KIT, LTF, PTPN6, RAG2, RPL22, SATB1, SOS2, SRF, STAT6, ADAM17, TAL1, TPD52, TSC1, TYRO3, TYROBP, WNT1, FZD5, FZD7, FZD8, FZD9, CUL4A, PIR, INPP4B, TNFSF18, GPR55, SOX13, GAB2, RNF41, DHRS2 |
1045 | GO:1903649 | 0.00 | 2.15 | 45.48 | 76 | 193 | regulation of cytoplasmic transport | ABL1, AGTR2, ANGPT1, ARF1, ATP1A2, BARD1, BAX, BCL3, BMP4, BMPR1A, CALM3, CASQ1, CASQ2, CD4, CD36, CDH1, CDKN1A, CYBA, DIAPH1, EDA, EDNRA, F2, F2R, PTK2B, GAS1, GNAQ, HCLS1, HRC, IGF1, IL10, IL12B, IL13, IL18, INSIG1, KPNA1, IPO5, SMAD3, PPP1R12A, TONSL, NTSR1, P2RX3, P2RX4, P2RX5, P2RX7, PRDX1, PLN, PPM1B, PRKCE, PRKD1, PRKCQ, PTPN6, RANGAP1, RBM4, RYR2, XCL1, SFRP5, SLC9A1, SNCA, SP100, TRIP6, TRPC1, TRPC3, ZIC1, AAAS, AKAP1, FZD7, DYRK2, RGS20, TNFSF14, INPP4B, SLC9A3R1, GSTO1, AKAP6, ATG5, LITAF, NUTF2 |
1046 | GO:0009653 | 0.00 | 2.15 | 33.03 | 56 | 150 | anatomical structure morphogenesis | APLNR, ANG, PHOX2A, ATRX, BCL3, BICD1, KLF5, BYSL, COL15A1, CSPG4, CST6, DUSP1, TYMP, EGR3, EN1, EYA4, EZH1, F2R, FAP, GNAQ, GPLD1, GPX1, GSC2, NR4A1, HOXC10, HOXD12, HPGD, IL18, KRT35, LAMA3, MEOX2, CNOT2, PCSK5, PRCP, PTPRJ, S100A7, SHB, SRPK2, NR2F2, TP73, TPD52, VTN, XRCC2, ZNF141, ZBTB17, VEZF1, SCG2, CLTCL1, FZD8, RGS20, DYRK1B, EIF2AK3, SOX13, SLC12A6, ARFRP1, ATP6AP2 |
1047 | GO:0060041 | 0.00 | 2.15 | 16.04 | 27 | 68 | retina development in camera-type eye | ACTL6A, ATP2B1, BAX, BMP4, CRX, GNAT1, GNAT2, GPM6A, IHH, IMPDH1, IMPDH2, NTRK2, SERPINF1, PTN, RARB, PRPH2, RPGR, RPL24, RRM1, SIX3, SMARCA4, SMARCD3, SOX9, TULP1, IFT140, NR2E3, IRX5 |
1048 | GO:1901605 | 0.00 | 2.14 | 24.44 | 41 | 104 | alpha-amino acid metabolic process | ADSS, ARG2, CKM, SARDH, DNMT1, DNMT3B, FAU, LIPC, P4HA1, PFAS, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, SMS, STAT5B, TYMS, P4HA2, RPL14, RPL23, EIF4A3, PTDSS1, NR1H4 |
1049 | GO:0006006 | 0.01 | 2.14 | 10.09 | 17 | 43 | glucose metabolic process | CACNA1A, CALM3, GAA, GYS2, ONECUT1, INPPL1, KCNJ11, PHKA2, PHKB, PHKG1, PPP2R5D, PRKAA1, PYGB, PYGM, SORD, UBB, USF1 |
1050 | GO:0042035 | 0.01 | 2.13 | 12.53 | 21 | 53 | regulation of cytokine biosynthetic process | BCL3, CD3E, CD4, CD28, CD86, TNFRSF8, GHSR, HSPB1, IFNG, IL1A, IL10, IL12B, INHA, IRF1, PRG2, PRKCQ, PTAFR, SFTPD, STAT5B, KLF4, PRG4 |
1051 | GO:0019439 | 0.04 | 2.13 | 6.54 | 11 | 28 | aromatic compound catabolic process | BLVRA, COMT, CYP2A6, DBH, GSTZ1, HNMT, IDO1, PAH, QDPR, TAT, KYNU |
1052 | GO:0015718 | 0.00 | 2.13 | 20.32 | 34 | 86 | monocarboxylic acid transport | ABAT, ACACB, AGTR2, ALB, ABCD1, ANXA1, CACNA1A, CACNB4, CD36, AKR1C4, CPT1B, CPT2, ACE, DRD3, GOT2, NTSR1, P2RX4, P2RX7, P2RY2, ABCD3, RXRA, SLC6A13, SLC10A1, SLCO2A1, SLCO1A2, SLC22A5, TRPC4, SLC10A3, SLC5A6, SLC16A6, SLC16A5, SLC9A3R1, NR1H4, ABCC4 |
1053 | GO:0007423 | 0.00 | 2.13 | 31.11 | 52 | 133 | sensory organ development | ACTL6A, ACVR2B, ACVRL1, ASCL1, ATP2B1, BMPR2, CDK2, CDK4, CRX, CRYBA1, CRYBA4, CTNS, GABRA5, GPD2, GPM6A, HSF4, IGF1, RBPJ, IMPDH1, IMPDH2, JUN, KCNK2, KCNK3, KCNQ1, LIM2, SMAD3, NTF4, NTRK3, SERPINF1, RARA, RCN1, PRPH2, RPL24, RRM1, RXRA, SDC4, SMARCA4, SMARCD3, SOX3, SPARC, SRF, TULP3, VIM, FZD4, LIN7A, PHOX2B, KLF4, ATG5, CXCL14, IFT140, ZEB2, BCL2L11 |
1054 | GO:0051240 | 0.00 | 2.13 | 161.03 | 260 | 687 | positive regulation of multicellular organismal process | ABAT, ABL1, ABL2, ACACB, ACVR2B, ADRA1B, AGTR2, ALB, ALOX15B, ANGPT1, ANGPT2, ANXA1, ANXA3, BIRC3, APOH, ARF1, ARNT, ARNTL, ASCL1, ATF4, ATP1A1, ATP2A1, AVPR1B, AVPR2, AXL, BAD, ADGRB2, BCL3, PRDM1, BMPR1A, BTK, TSPO, C3, CASP5, CBLB, CCNB1, CD3E, CD4, CD6, CD28, CD86, TNFRSF8, CD36, CD58, CDC20, CHRM3, CHRNB4, CHUK, CLU, CCR3, CNR1, COL1A1, CPS1, CRH, CRX, CSF1R, CTH, CTSH, CX3CR1, BRINP1, DBH, DLX5, DNMT3B, DPYSL3, DRD3, ECM1, LPAR1, EDNRA, EFNA5, EGR3, CTTN, EP300, EPHB1, EPHB2, EPHB3, ETS1, ETV5, F3, F7, PTK2B, FGA, FGF3, FGF7, FGR, FLT1, FLT3LG, FLT4, FYN, GALR1, GATA4, GATA6, GFAP, GNAS, GOLGA4, GPLD1, FFAR3, RAPGEF1, HCLS1, HGF, NRG1, HMGCR, FOXA2, HOXC11, HRH1, HRC, HSPB1, ICAM1, IFI16, IFNG, IGF1, RBPJ, IL1A, IL2RA, IL10, IL12RB2, IL13, ILK, IDO1, INHA, INS, IRAK1, IRF1, IRF5, ISL1, ITGA5, ITGB1, JUN, JUND, KCNQ1, KDR, KISS1, KIT, KNG1, LIMK1, LTF, CAPRIN1, KITLG, NRCAM, NTRK2, NTRK3, OPA1, OTX2, OXTR, P2RX3, P2RX7, PAEP, SERPINE1, PALM, PCP4, PDE4B, SERPINF1, PENK, PRG2, PRKAA1, PRKCI, PRKD1, PRKCQ, PTAFR, PTGIS, PTGS1, PTN, RAG1, RAG2, RARA, RARB, RB1, RFX3, RHEB, RPS6KB1, RPS19, RYR2, S100A9, SALL1, XCL1, CX3CL1, SEC14L1, SELP, SGK1, SHC1, SLC9A1, SLC22A5, SMARCD3, SNAI1, SOX10, SOX11, SPARC, SRF, SRY, TRIM21, STAT6, SYT1, SYT4, ADAM17, TACR3, TAL1, KLF10, TNR, TP73, TPBG, NR2C2, TRAF2, TRPC3, TNFSF4, UBB, UNG, NR1H2, USF1, VEGFB, VIP, TRPV1, WNT1, WNT11, XRCC2, XRCC5, ZNF16, RNF112, FZD5, RND2, OGT, IKBKG, AP3B1, TP63, PTCH2, NUMB, PDE5A, VAMP8, TRADD, RIPK1, TNFSF9, RIPK2, NRP2, NRP1, PHOX2B, AP3D1, USP2, CBFA2T2, IL1RL1, ARHGEF2, PDLIM7, ITGB1BP1, SLIT2, NRXN3, NRXN1, LIPG, GSTO1, EIF2AK3, IL27RA, AKAP6, BCAR1, RAPGEF2, RIMS2, CUL7, ZEB2, RBM19, RNF10, HDAC6, PDCD6, ATP6AP2, OLIG2, SPRY1 |
1055 | GO:0030335 | 0.00 | 2.13 | 35.38 | 59 | 151 | positive regulation of cell migration | ANGPT1, ANXA3, BMP4, BMPR2, COL1A1, CSF1R, CTSH, DAPK3, DIAPH1, S1PR1, ETS1, F2R, F10, FBLN1, FGF7, FGR, FLT1, FLT4, FSHB, GPLD1, GRB7, HGF, ONECUT1, HSPB1, IFNG, IGF1R, ILK, INS, ITGA5, ITGAV, ITGB1, JUN, KDR, KIT, SMAD3, NTRK3, PRKCE, PRKD1, PTK2, SEMA3F, SNAI1, SOX9, SPARC, TRIP6, VIL1, WNT11, SEMA3B, IKBKAP, NUMB, NRP2, ARHGEF7, ITGB1BP1, ONECUT2, BAG4, BCAR1, RAPGEF2, SEMA3E, HDAC6, PDCD6 |
1056 | GO:0051306 | 0.01 | 2.13 | 11.34 | 19 | 48 | mitotic sister chromatid separation | BUB1B, CCNB1, CDC20, CDC27, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, PPP2R1A, PTEN, RB1, TTK, ZNF207, CUL3, CDC23, CDC16, ZW10, DLGAP5 |
1057 | GO:0040011 | 0.00 | 2.13 | 131.19 | 214 | 577 | locomotion | ACTB, AGTR1, ANG, APP, ARAF, ASCL1, ASTN1, RERE, ATP1A2, ATP2B2, BAX, DST, BSG, TSPO, CACNB4, CALM3, CAMK2A, CD44, CD58, CD72, CD151, CHN1, AP2S1, CCR3, CCR8, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF2RB, CSNK2A1, CSNK2A2, VCAN, CSPG4, CTGF, DBH, DCC, DLG3, DLX5, DNM1, DNAH8, DUSP5, TYMP, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EGR3, CTTN, EMX2, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, ERG, ETV4, F2, FAP, FGF3, FGFR3, FPR1, FPR3, FUT8, FYN, GFRA1, B4GALT1, GPM6A, XCR1, GPR15, GPX1, GRB2, GRIN2A, HIST1H1T, HEXB, NR4A1, HRH1, IL2RA, IL10, IL12B, ING2, ISL1, ITGA1, ITGA9, ITGAM, KIF5A, KRT2, LDHC, LIMK1, MARK3, SMCP, NRCAM, NTRK2, NTN3, OGDH, OLR1, OTX2, PAX3, PCM1, PDE4B, PEX7, PEX13, PIK3C2B, PPP5C, PRKCI, PRKCQ, PSPN, PROC, PSG2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTPN6, PTPRA, RAB1A, RALA, RASA2, RFX3, RNASE2, RPL24, RPS6KA1, RPS19, RYK, S100A2, S100A8, S100A9, S100A12, SAA4, SCN5A, SCNN1B, CCL22, SELL, SFTPD, SHC1, SIX3, SLC9A1, FSCN1, SORD, SOS2, SOX10, SPOCK1, STAT5B, XCL2, CNTN2, NR2F1, TNR, TOP2B, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, CLRN1, VAV1, ARHGEF5, FOSL1, FGF23, SLC7A5, USP9X, USP9Y, FZD4, CUL3, SORBS2, CNTNAP1, KLF7, PEA15, PHOX2B, RPS6KA4, DOK2, NRXN3, NRXN1, PSMF1, NRG2, CDC42BPB, FEZ2, SDC3, ARHGEF11, ZEB2, GAB2, KIAA0319, RBX1, RANBP9, ARPC5, ARPC1B, ACTR2, ARPC2, AKAP9, ABI2, RASA4, WASF2, PSME3, PSMD14, RCAN2 |
1058 | GO:0042552 | 0.02 | 2.13 | 8.94 | 15 | 38 | myelination | CD9, LPAR1, EGR2, HEXB, ILK, MAL, SCN2A, SCN8A, SLC8A3, TSC1, ZNF24, ATRN, CNTNAP1, EIF2B2, OLIG2 |
1059 | GO:0002429 | 0.00 | 2.13 | 43.96 | 73 | 186 | immune response-activating cell surface receptor signaling pathway | ABL1, ACTB, BAX, BLK, BTK, CACNB4, CALM3, CBLB, CD3D, CD3E, CD3G, CD4, CD28, CHUK, CR2, CTLA4, EP300, FGR, FYB, FYN, GPLD1, GRB2, ICAM2, ITPR1, KCNN4, LIMK1, PDE4B, PRKACB, PRKACG, PRKCE, PRKCQ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, PTPN6, PTPRJ, RAC1, RAF1, SKP1, UBB, UBE2D2, VAV1, LAT2, CUL1, IKBKG, RIPK2, UBA3, GRAP2, PSMF1, BCAR1, ARPC5, ARPC1B, ACTR2, ARPC2, WASF2, PSME3, PSMD14 |
1060 | GO:0000724 | 0.00 | 2.13 | 16.74 | 28 | 71 | double-strand break repair via homologous recombination | ABL1, ATR, CDK2, CHEK1, ERCC4, FEN1, TONSL, PPP4C, RFC3, RFC4, RFC5, RPA2, RPA3, SFPQ, UBB, SUMO1, YY1, HIST1H4I, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HERC2, RNF8, REC8, PSMD14 |
1061 | GO:0009168 | 0.01 | 2.12 | 10.15 | 17 | 43 | purine ribonucleoside monophosphate biosynthetic process | ADSS, AK1, AK2, AMPD1, AMPD2, APRT, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, LDHC, PFAS, STAT3, SLC25A13 |
1062 | GO:0034762 | 0.00 | 2.12 | 31.20 | 52 | 133 | regulation of transmembrane transport | ABL1, ARF1, BAX, CACNA1A, CACNA1B, CASQ1, CLCN3, CLCN6, CLCN7, CLCNKA, CLCNKB, CYBA, DIAPH1, DPP6, EDNRA, F2, F2R, GCG, IL13, KCNA1, KCNA3, KCNA4, KCNC2, KCND2, KCND3, KCNJ2, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ14, KCNJ16, KCNS3, P2RX7, PRKD1, PTPN6, SCN1A, SCN2A, SCN5A, SCN7A, SCN8A, XCL1, SLC34A1, SNCA, STC1, TRPC1, VDAC2, KCNAB3, KCNK6, ATG5, HCN4 |
1063 | GO:0051049 | 0.01 | 2.12 | 11.84 | 20 | 53 | regulation of transport | ABCA2, AGTR1, CHRNB4, GDF9, GFAP, HTR2C, PPP1R12A, NTRK2, NUP98, RANBP2, RBM4, RPS6KB1, RTN2, TNNC1, NUP214, AAAS, INPP4B, SNCAIP, NUP155, NUP93 |
1064 | GO:0048663 | 0.02 | 2.12 | 8.98 | 15 | 38 | neuron fate commitment | ASCL1, BMP4, EVX1, NRG1, FOXA2, HOXC10, HOXD10, RBPJ, IHH, ISL1, NTRK3, OTX2, PAX3, WNT1, OLIG2 |
1065 | GO:0050830 | 0.02 | 2.12 | 8.98 | 15 | 38 | defense response to Gram-positive bacterium | ANG, APP, TNFSF8, CD36, CRP, FAU, FCN2, FGR, P2RX7, RPL39, ADAM17, VIP, HIST2H2BE, RIPK2, IL27RA |
1066 | GO:0002682 | 0.00 | 2.11 | 16.01 | 27 | 72 | regulation of immune system process | ANXA5, ARF1, AP1S1, AP2S1, COX8A, GABRA5, KCNQ1, NTHL1, ORM2, PDK4, PEX13, SCN1A, SNRPD1, STK10, ZNF189, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, AP1M1, HIST1H3F, CHST3, NUP93, PHYHIP, FGFBP1, AP1M2 |
1067 | GO:1903706 | 0.00 | 2.11 | 22.83 | 38 | 97 | regulation of hemopoiesis | ARNT, ATP6AP1, AXL, BAD, BGLAP, PRDM1, BTK, CD28, CD86, CREB1, CSF1R, ACE, EGR3, ETS1, FLT3LG, FSHB, FSHR, GNAS, HCLS1, IFNG, IL2RA, IL12B, JUN, KITLG, PTPN6, RAG1, RB1, TAL1, KLF10, TYROBP, OGT, AP3B1, RIPK1, TNFSF9, RIPK2, AP3D1, SOX13, RNF41 |
1068 | GO:0043065 | 0.00 | 2.11 | 46.54 | 77 | 199 | positive regulation of apoptotic process | ABL1, ALDH1A3, ANXA1, ANXA5, ARHGAP4, BARD1, BCL2A1, BMP4, BNIP3L, TSPO, CAMK2A, TNFRSF8, CDK4, CNR1, COL4A3, CREB1, CRYBA1, CTGF, CTLA4, DFFA, DNM2, DUSP1, LPAR1, ERCC3, F2R, F3, FGD1, B4GALT1, GPLD1, GRIN2A, HIP1, HMGCR, HRG, IFNG, IGFBP3, IL10, IL12B, IDO1, ING2, IRF5, ITGB1, KNG1, NTRK3, NTSR1, P2RX1, P2RX7, PPID, PRKCI, PTN, RAC1, RARB, REST, RPS6, RXRA, SORT1, SLC9A1, SNCA, SOS2, TOP2A, VAV1, TRPV1, WNT11, FOSL1, NSMAF, KLF11, UNC5C, AKR1C3, RIPK2, ARHGEF7, LATS1, ARHGEF2, SLIT2, RAPGEF2, ARHGEF11, TNFSF15, CASP8AP2, PDCD6 |
1069 | GO:0048645 | 0.03 | 2.11 | 7.80 | 13 | 33 | organ formation | BMP4, BMPR1A, FGF3, GATA6, HHEX, HOXC11, RBPJ, ISL1, NTF4, PAX3, SMARCD3, TP63, SPRY1 |
1070 | GO:0070059 | 0.03 | 2.11 | 7.80 | 13 | 33 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | APAF1, ATF4, ATP2A1, BAX, GRINA, UBE2K, ITPR1, OPA1, TRAF2, WFS1, TNFRSF10B, EIF2AK3, BCL2L11 |
1071 | GO:0009314 | 0.00 | 2.11 | 17.38 | 29 | 75 | response to radiation | ALAD, ANGPT2, ANXA1, BCL2L1, CYBA, DNMT1, DNMT3B, FANCG, GRB2, ICAM1, IFI16, IGF2, IL1R1, JUN, KRT13, MGMT, PENK, RAD51, RAD51C, RAD51B, RAD51D, RRM1, XRCC2, XRCC5, SMC1A, PPM1D, MBD4, SOCS3, RNF8 |
1072 | GO:0051241 | 0.00 | 2.10 | 71.81 | 118 | 309 | negative regulation of multicellular organismal process | ABAT, ACVRL1, ANXA5, APP, ARHGAP4, ARHGDIB, ASCL1, ASCL2, ATP2A1, AVPR2, BCR, BMPR1A, BRCA2, CAV3, CD86, CD63, CHAD, COMT, CRH, CRHBP, CTNNA1, CXADR, CYBA, DCC, DDX6, DPYSL3, DRD3, TSC22D3, ECM1, LPAR1, EFNA1, EIF4E, ETV4, F2, FAP, FGA, FGF3, FGFR3, GDI1, GFAP, GLRA1, GNAS, GP1BA, NRG1, FOXA2, IAPP, IGF1, RBPJ, ISL1, ITGB1, KCNK2, KLKB1, KNG1, LRPAP1, SMAD3, SMAD7, CIITA, NTRK3, OXTR, P2RX4, P2RX7, P2RY2, PCM1, PDE4B, PFN2, PRKACB, PROC, PTEN, PTK2, PTPRR, RAP1GAP, REST, RNF6, RPS19, SALL1, SEMA3F, SFRP5, SIX3, SNAI1, SOX3, SOX11, SP100, SPOCK1, SRF, STAT3, STC1, CNTN2, DYNLT1, NR2F2, TNR, TP73, TTC3, TULP3, USF1, VIM, VTN, SEMA3B, FGF23, AKAP1, FZD7, TP63, CHRD, NRP1, PHOX2B, USP2, RGN, ARHGEF1, CBFA2T2, CTDP1, ARHGEF2, SLIT2, EIF2AK3, BAG5, AATK, RAPGEF2, KIAA0319, RNF10, OLIG2 |
1073 | GO:0001701 | 0.00 | 2.10 | 33.24 | 55 | 141 | in utero embryonic development | ACVRL1, ADAM10, ADAR, ADD1, ANGPT1, ARNT, ASCL2, BCL2L1, PRDM1, BMPR1A, BTF3, CCNB1, DDX5, EDNRA, EMX1, FUT8, GATA4, GATA6, KAT2A, GRB2, HHEX, FOXA2, RBPJ, IHH, IL10, ITGA4, ITGB1, LLGL2, SMAD3, YBX1, P2RY2, PTPRR, RBBP6, RCN1, RXRA, SRSF1, STIL, SNAI1, SOX10, ST14, NR2F2, KDM6A, XRCC2, FZD5, FOSL1, USP9X, CUL4A, COPS3, EIF2S2, SOCS3, CCNB2, SLIT2, APBA3, BCL2L11, COL4A3BP |
1074 | GO:0006753 | 0.00 | 2.10 | 53.45 | 88 | 227 | nucleoside phosphate metabolic process | ABCA1, ACACB, ACPP, ADSS, AMPD1, AMPD2, APRT, ATP1A2, ATP2B2, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1B2, ATP6V0A1, AVPR2, TSPO, CACNB4, CALM3, CDA, COX8A, COX15, CRH, CTNS, DHFR, DRD3, DRD5, TYMP, LPAR1, EDNRA, PTK2B, FSHR, FZD2, GALR1, GCG, GHRHR, GNAS, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GUCY2D, HMGCR, HTR2C, IDH1, IMPDH1, IMPDH2, LDHC, MDH2, NTRK2, P2RY11, PALM, PFAS, PRPSAP1, PTGIS, RAF1, RCVRN, RPE, RRM1, SDHC, SHMT1, SNCA, SULT1E1, SULT1A3, SULT1C2, SULT2B1, TAZ, TYMS, UQCRC1, UQCRC2, UQCRH, VIP, VIPR2, WFS1, PDHX, SUCLG1, KYNU, PAPSS1, AKAP6, TBPL1, TP53I3, GABBR2, AKAP12, GUCA1C, SLC25A13 |
1075 | GO:0070838 | 0.00 | 2.10 | 51.05 | 84 | 216 | divalent metal ion transport | ABL1, ANXA5, ANXA6, ATP1A2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, BAX, BMP4, TSPO, CACNA1A, CACNA1B, CACNB4, CALM3, CAMK2A, CASQ1, CASQ2, CAV3, CD4, CHRNB2, CLCA1, CRH, CTGF, CYBA, DIAPH1, EDNRA, F2, F2R, PTK2B, FYN, GCG, GJA4, GPM6A, XCR1, FFAR1, GRIN2A, HRC, HTR2C, ICAM1, IGF1, IL13, ITGAV, ITPR1, KCNJ2, KCNN4, NTSR1, P2RX1, P2RX3, P2RX4, P2RX5, P2RX7, PDE4B, PLN, PRKCE, PRKD1, PTPN6, RCVRN, RYR1, RYR2, S100A1, CCL21, XCL1, SLC8A3, SLC9A1, SNCA, SPINK1, STC1, TPT1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, SUMO1, TRPV1, WFS1, SLC30A2, TUSC3, RGN, GSTO1, AKAP6, ATG5, RAMP3 |
1076 | GO:0007610 | 0.00 | 2.10 | 33.12 | 55 | 144 | behavior | ABL2, AGTR2, AMPH, APRT, STS, BCHE, TSPO, CHAT, COMT, CREB1, CTNND2, CX3CR1, DBI, EIF4E, FEN1, AFF2, FYN, GABRA5, GCG, GHSR, GM2A, GRIA1, GRIN2A, HMGCR, HRH1, IAPP, IGF1, IGF2, ITGA5, ITGB1, JUN, KCNK2, KIT, MAN2B1, NTRK2, P2RX3, SERPINF1, PRKAR1B, PRKAR2B, PTGS1, PTN, RPS6KB1, SGK1, SLC8A3, SRF, VIP, TRPV1, KCNAB1, FOSL1, AAAS, FZD9, DDO, DGKI, RIN1, EIF4A3 |
1077 | GO:0001736 | 0.05 | 2.10 | 6.62 | 11 | 28 | establishment of planar polarity | ABL1, ABL2, DLG3, GPC4, FZD2, RAC1, RYK, WNT11, FZD6, FZD7, TP63 |
1078 | GO:0006833 | 0.05 | 2.10 | 6.62 | 11 | 28 | water transport | AQP5, AQP6, AVPR2, GNAS, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, UPK3A |
1079 | GO:0006968 | 0.05 | 2.10 | 6.62 | 11 | 28 | cellular defense response | CCR3, CX3CR1, PTK2B, ITGB1, KLRC3, TYROBP, ZNF148, VEZF1, FOSL1, KLRC4, PAGE1 |
1080 | GO:0042733 | 0.05 | 2.10 | 6.62 | 11 | 28 | embryonic digit morphogenesis | BAX, BMP4, BMPR1A, GNAQ, HOXC11, HOXD12, IHH, SALL1, TULP3, FZD6, BCL2L11 |
1081 | GO:0048736 | 0.00 | 2.10 | 21.74 | 36 | 92 | appendage development | ALX3, ATRX, BAX, BMP4, BMPR1A, BMPR2, RUNX2, COMP, DLX5, EN1, FGF4, GPC3, GNAQ, GNAS, HOXC10, HOXC11, HOXD9, HOXD10, HOXD12, IDUA, IHH, MEOX2, PAM, PCSK5, RARA, RARB, SALL1, SOX9, SOX11, NR2F2, TULP3, ZNF141, FZD6, TP63, IFT140, BCL2L11 |
1082 | GO:0051674 | 0.00 | 2.10 | 171.10 | 273 | 724 | localization of cell | ABL1, ABL2, ACVRL1, ADAM10, AGTR1, AGTR2, ALOX15B, ANG, ANGPT1, ANGPT2, ANXA1, ANXA3, ANXA5, APOH, ARHGAP4, ARHGDIB, ASCL1, ASTN1, RERE, AXL, BAX, BBS4, BCR, BMP4, BMPR2, DST, BSG, BST2, TSPO, KRIT1, CD44, CD58, CD63, CD151, CDK6, COL1A1, CSF1R, VCAN, CSPG4, CTGF, CTNNA1, CTSH, CX3CR1, CXADR, DAPK3, DBH, DCC, DCN, ACE, DIAPH1, DNAH8, DPEP1, DPP4, DPYSL3, ECM1, S1PR1, LPAR1, EDNRA, EFNA1, EFNB1, EGR3, EPHA2, EMP2, CTTN, EMX2, EPHA8, EPHB1, EPHB3, ERG, ETS1, F2, F2R, F3, F7, F10, PTK2B, FAP, FBLN1, EFEMP1, FGF4, FGF7, FGR, FLT1, FLT4, FSHB, FUT8, FYN, B4GALT1, GPLD1, GPM6A, GPR15, GPX1, GRB2, GRB7, CXCL3, HIST1H1T, HEXB, HGF, NRG1, NR4A1, ONECUT1, HRH1, HRG, HSPB1, ICAM1, IFNG, IGF1, IGF1R, IGFBP3, IL10, IL12B, ILK, ING2, INS, ISL1, ITGA1, ITGA4, ITGA5, ITGA9, ITGAM, ITGAV, ITGB1, JUN, KDR, KIT, KRT2, LAMA3, LAMA4, LDHC, SMAD3, SMAD7, SMCP, KITLG, NRCAM, NTRK2, NTRK3, OGDH, OLR1, P2RY2, P2RY6, SERPINE1, PAX3, PCM1, PDE4B, SERPINF1, PEX7, PEX13, PF4V1, PFN2, PIK3C2B, PRCP, PRKCE, PRKCI, PRKD1, PRKCQ, PRKX, PROC, PSG2, PTAFR, PTEN, PTK2, PTN, PTPN6, PTPRJ, PTPRR, RAB1A, RAC1, RAC2, RAF1, RAP2A, RAP2B, RFX3, RPS6KB1, RPS19, S100A2, S100A7, S100A8, S100A9, S100A12, SAA4, SCNN1B, CCL21, CCL22, CCL25, CXCL6, CXCL5, XCL1, CX3CL1, SDC4, SELE, SELL, SELP, SELPLG, SEMA3F, SFTPD, SGK1, SHC1, SIX3, SLC9A1, SNAI1, FSCN1, SORD, SOX9, SOX10, SP100, SPARC, SPOCK1, SRF, STAT3, STAT5B, STC1, STK10, XCL2, ADAM17, CNTN2, NR2F1, NR2F2, TNR, TOP2B, TRIP6, TYRO3, CLRN1, VAV1, VEGFB, VIL1, VTN, WNT11, SCG2, SEMA3B, ARHGEF5, SLC7A5, MADCAM1, USP9X, USP9Y, SOX14, CUL3, SORBS2, IKBKAP, UNC5C, CHRD, NUMB, TNFSF14, ADAM15, TNFRSF18, NRP2, NRP1, ARHGEF7, PHOX2B, TNFSF18, DOK2, RGN, ITGB1BP1, KLF4, SLIT2, SLC9A3R1, ONECUT2, BAG4, CXCL14, BCAR1, CDC42BPB, SDC3, RAPGEF2, SEMA3E, SLK, ZEB2, GAB2, KIAA0319, HDAC6, PDCD6, ARPC5, ABI2, WASF2, RNF41 |
1083 | GO:0006094 | 0.01 | 2.09 | 12.05 | 20 | 51 | gluconeogenesis | ALDOC, ATF4, ENO2, G6PC, GAPDH, GCG, KAT2A, GOT2, GPD2, INS, MDH2, PCK1, PCK2, PGAM1, PRKACB, PRKACG, RANBP2, OGT, SLC25A12, SLC25A13 |
1084 | GO:0046777 | 0.00 | 2.09 | 23.56 | 39 | 100 | protein autophosphorylation | ALK, ATR, BCR, CALM3, CAMK2A, CLK1, CLK3, CSF1R, DAPK3, EPHA8, EPHB1, EPHB3, FGFR3, FLT1, FLT3, FLT4, INS, INSRR, IRAK1, JUN, KIT, MAP3K11, NTRK2, NTRK3, PIM1, PRKD1, PRKX, RAP2A, RAP2B, STK10, TYRO3, VRK1, STK16, RIPK1, AURKB, STK17B, EIF2AK3, SLK, RAD50 |
1085 | GO:0007565 | 0.00 | 2.09 | 19.32 | 32 | 82 | female pregnancy | ARHGDIB, STS, BYSL, COMT, CRH, CRHBP, EPYC, EMP2, ETS1, FBLN1, FSHB, GNAS, HPGD, IGF1, IGF2, IDO1, OVGP1, OXTR, PCSK5, PSG2, PSG3, PSG5, PSG6, PSG9, PSG11, PZP, RARA, SP1, STAT5B, SULT1E1, SCGB1A1, FOSL1 |
1086 | GO:0002262 | 0.00 | 2.09 | 16.31 | 27 | 69 | myeloid cell homeostasis | ADAR, ADD1, ALAS2, ANXA1, ARNT, AXL, BAX, BMP4, CDK6, ETS1, HCLS1, IFNG, INHA, KIT, KITLG, PRDX1, PDE4B, RB1, RHAG, RPS19, SP1, SRF, STAT5B, ADAM17, TAL1, ZNF16, BCL2L11 |
1087 | GO:0051347 | 0.00 | 2.09 | 97.37 | 158 | 412 | positive regulation of transferase activity | ABL1, ACVR2B, ALK, ANG, ANGPT1, ARAF, BAD, BAX, BMI1, BMP4, CALM3, CAMK2A, CCNB1, CCNC, CCNT2, CD4, CDC20, CDC27, CDKN1A, CENPE, CLU, CRKL, CSF1R, CSF2RB, CSPG4, ACE, DKC1, DUSP5, LPAR1, EFNA1, EFNA5, EMP2, EPHA8, ERCC6, F2R, PTK2B, FGF3, FGF4, FGF7, FGFR3, FGR, FLT1, FLT3, FPR1, FYN, GCG, GNG3, GRB2, RAPGEF1, GRIN2A, GRM1, HGF, NRG1, IGF2, IL2RA, IL12B, ILK, INS, IRAK1, IRAK2, ITGA1, KIT, LTF, MARK3, KITLG, MAP3K11, NTRK3, NVL, P2RX7, PIM1, PPP5C, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCQ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, PTPRA, RAC1, RAF1, RASA2, RPS3, S100A12, CCL21, SDC4, SHC1, STIL, SKP1, SNCA, STK10, ADAM17, TP73, TPD52L1, TRAF2, UBB, UBE2L3, WNT11, ZNF16, FZD5, ARHGEF5, FGF23, FZD4, FZD8, CUL3, CUL1, IKBKG, CDC14B, PDE5A, PEA15, CDC23, RIPK1, RIPK2, TNFRSF10B, TNFRSF10A, CDC16, UNC119, AURKB, VAPB, ITGB1BP1, KLF4, PSMF1, NRG2, TRAF4, RAPGEF2, SLK, ATG13, ZEB2, EPM2AIP1, OXSR1, TNFSF15, RBX1, RAD50, AKAP9, RASA4, PSME3, PSMD14 |
1088 | GO:0071900 | 0.00 | 2.09 | 79.17 | 129 | 335 | regulation of protein serine/threonine kinase activity | ABL1, ALK, ANGPT1, ARAF, BMP4, CALM3, CAMK2A, CAV3, CCNC, CCNT2, CDC25A, CDC25C, CDKN1A, CKS1B, CRKL, CSF1R, CSF2RB, CSPG4, DUSP1, DUSP5, LPAR1, EFNA1, ERCC6, F2R, PTK2B, FGF3, FGF4, FGF7, FGFR3, FLT1, FLT3, FPR1, FYN, GNG3, GRB2, RAPGEF1, GRIN2A, GRM1, HGF, NRG1, HHEX, HMGCR, HSPB1, IGF1R, IGF2, IL2RA, ILK, IRAK1, IRAK2, ITGA1, KIT, LTF, MARK3, KITLG, MAP3K11, NTRK3, P2RX7, PIM1, PPP2R1A, PPP5C, PRKAA1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, PTPN6, PTPRA, PTPRJ, RAF1, RASA2, RPS3, S100A12, SHC1, STIL, SNCA, ADAM17, NR2F2, TP73, TPD52L1, TRAF2, TSG101, UBB, UVRAG, FZD5, ARHGEF5, FGF23, FZD4, FZD8, CUL3, IKBKG, PDE5A, PEA15, RIPK1, RIPK2, TNFRSF10B, TNFRSF10A, DIRAS3, LATS1, PSMF1, NRG2, TRAF4, RAPGEF2, ZEB2, TNFSF15, RBX1, AKAP9, RASA4, PSME3, PSMD14, SPRY1 |
1089 | GO:0045216 | 0.01 | 2.09 | 12.66 | 21 | 54 | cell-cell junction organization | ARL2, CD9, CLDN3, CSF1R, CXADR, ACE, GJA4, GJB1, ITGB1, LIM2, PRKCI, SNAI1, FSCN1, SRF, STRN, WNT11, FZD5, CNTNAP1, CLDN12, CLDN6, CLDN1 |
1090 | GO:0022407 | 0.00 | 2.09 | 30.30 | 50 | 129 | regulation of cell-cell adhesion | BAD, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD28, CD86, CD44, CD59, CLC, DPP4, EFNA5, EFNB1, EGR3, EPHB3, FGA, FLOT2, FYN, GRB2, FOXA2, IFNG, IGF1, IGF2, IL12B, IL18, ITGA4, LMO1, SMAD7, PRKCQ, PTAFR, RAC1, RAC2, RAG1, RAP1GAP, RARA, CX3CL1, SOS2, STAT5B, TRAF2, VAV1, AP3B1, TNFSF14, TNFSF9, RIPK2, AP3D1, GRAP2, SOX13, PIEZO1 |
1091 | GO:0051251 | 0.00 | 2.09 | 30.96 | 51 | 131 | positive regulation of lymphocyte activation | ANXA1, AXL, BAD, PRDM1, BTK, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD28, CD86, CD59, CDKN1A, CHRNB2, CTLA4, DPP4, EFNB1, EGR3, FLOT2, FLT3LG, FYN, GRB2, IFNG, IGF1, IGF2, IHH, IL2RA, IL12B, IL13, IL18, PRKCQ, PTPN6, RAC1, RAG1, RARA, CCL21, XCL1, STAT5B, STAT6, TRAF2, TNFSF4, UNG, VAV1, AP3B1, TNFSF14, TNFSF9, RIPK2, AP3D1, GRAP2 |
1092 | GO:0031346 | 0.03 | 2.08 | 8.44 | 14 | 36 | positive regulation of cell projection organization | BBS4, DNM2, EFEMP1, KAT2A, KIT, P2RX7, RAC1, RAC2, CLRN1, VIL1, WNT1, ARHGEF7, ARPC2, WASF2 |
1093 | GO:0007269 | 0.00 | 2.08 | 19.38 | 32 | 82 | neurotransmitter secretion | ABAT, CACNA1A, CACNA1B, CAMK2A, CHAT, CHRNB4, GAD1, NTRK2, P2RX7, PFN2, SEPT5, PTPRN2, RAB5A, SLC1A6, SLC6A13, SLC22A2, SNAP25, SNCA, SYN1, SYT1, SYT4, SYN3, STX11, LIN7A, SYNJ1, DGKI, SNAP29, NRXN3, NRXN1, NRXN2, SNCAIP, RIMS2 |
1094 | GO:0030522 | 0.00 | 2.08 | 37.10 | 61 | 157 | intracellular receptor signaling pathway | NR0B1, ALOX15B, BIRC3, XIAP, APP, ARNT, ARNTL, BCL2L1, CCNE1, CHUK, CRY2, DDX5, EP300, ESRRG, FLT1, NR5A2, GHRHR, NR4A1, HNF4G, IGF1, IRAK1, IRAK2, ISL1, SCGB2A1, CNOT2, P2RX7, PGR, PIM1, PPP5C, PRCP, PTGIS, RAN, RARA, RARB, RB1, RNF6, RXRA, RXRG, SEC14L1, SMARCA4, SP100, STAT3, TAF7, NR2F1, NR2F2, NR2C1, UBB, UBE3A, NR1H2, NRIP1, IKBKG, AKR1C3, RIPK2, BUD31, CLOCK, RNF14, NR1I3, NR1H4, NR1D2, NR2E3, HDAC6 |
1095 | GO:0031668 | 0.00 | 2.08 | 26.71 | 44 | 113 | cellular response to extracellular stimulus | ALB, ASGR1, ATF4, ATP2B1, AXL, BGLAP, BMPR2, CCNE1, CDKN1A, COL1A1, COMT, FOXA2, ICAM1, IFI16, ITGB1, JUN, P2RX7, PCK1, CHMP1A, PDK4, PENK, PIM1, PRKAA1, PTN, RHAG, RHCE, RHD, SIPA1, SRD5A1, SREBF1, SRF, KLF10, TSC1, UPP1, USF1, FOSL1, FGF23, PPM1D, AKR1C3, EIF2AK3, PICK1, ATG5, ATG13, NR1H4 |
1096 | GO:0000082 | 0.00 | 2.08 | 14.51 | 24 | 62 | G1/S transition of mitotic cell cycle | ANXA1, CAMK2A, CCNB1, CDC25A, CDK3, CDK4, CDK6, CKS1B, EIF4E, ITGB1, ORC2, ORC4, PPP6C, PRIM2, PTPN6, RPA3, RPS6KB1, SKP1, UBE2E2, CUL4A, CUL3, CUL2, CUL1, LATS1 |
1097 | GO:0051170 | 0.00 | 2.08 | 35.92 | 59 | 152 | nuclear import | ADAR, AGTR2, ANGPT1, ARNTL, RERE, BCL3, BMP4, BMPR1A, CBLB, CD36, CDH1, CDKN1A, CSE1L, EDA, F2R, FYB, GNAQ, HCLS1, IFNG, IGF1, IL10, IL12B, IL18, JUN, KPNA1, KPNA2, KPNA3, KPNA4, IPO5, SMAD3, TONSL, NUP98, PRDX1, PPM1B, PRKCQ, RAN, RANBP2, SFRP5, SIX3, SLC9A1, STAT3, TRIP6, ZIC1, NUP214, AKAP1, FZD7, DYRK2, RGS20, AKR1C3, TNFSF14, RPL23, SLC9A3R1, ZFYVE9, AKAP6, LITAF, NUP155, IPO13, NUP93, NUTF2 |
1098 | GO:0021537 | 0.00 | 2.08 | 24.27 | 40 | 103 | telencephalon development | ALDH1A3, ANXA3, ASCL1, AVPR2, BAD, BAX, BBS4, CDK6, CSF1R, CX3CR1, DBI, EPHA5, EZH1, KAT2A, NRG1, HPRT1, KCNA1, NTRK2, OGDH, OXTR, PEX13, PTEN, RAC1, RARA, RARB, SALL1, SCN5A, SLC8A3, SRD5A1, SRF, TACC1, CNTN2, TNR, TP73, TSC1, USP9X, NUMB, NRP1, SLIT2, ZEB2 |
1099 | GO:0044724 | 0.01 | 2.08 | 12.71 | 21 | 54 | single-organism carbohydrate catabolic process | ALDOC, ARNT, BAD, ENO2, FUT6, FUT8, GALE, GAPDH, GM2A, HEXB, IGF1, OGDH, P2RX7, PGAM1, PPP2R5D, PRKAA1, PRKAG1, RPE, STAT3, OGT, XYLB |
1100 | GO:0051289 | 0.02 | 2.08 | 9.69 | 16 | 41 | protein homotetramerization | ACACB, ACADS, CAT, CDA, CTH, GOLGA2, HPRT1, IMPDH2, KCNJ2, PEX5, RXRA, RXRG, SHMT1, SHMT2, SOD2, TP63 |
1101 | GO:0006446 | 0.01 | 2.08 | 13.94 | 23 | 59 | regulation of translational initiation | ATF4, DAZ1, DDX1, EIF2B1, EIF4A1, EIF4G2, EIF5, HSPB1, EIF3E, RARA, RBM4, RPS6KB1, RPS6KB2, RXRA, EIF4H, EIF4EBP3, EIF3G, EIF4G3, EIF2B3, EIF2B2, EIF2AK3, EIF5B, EIF1 |
1102 | GO:1901988 | 0.00 | 2.08 | 28.60 | 47 | 121 | negative regulation of cell cycle phase transition | BUB1B, CCNB1, CDC20, CDC27, CDK2, CDKN1A, CENPF, CSNK2A1, CSNK2A2, DUSP1, FOXO4, OVOL1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, RB1, RPA2, SMARCA4, SOX11, TP73, TTK, UBB, ZNF207, TP63, CDC23, CRADD, CDC16, ZW10, PSMF1, PSME3, PSMD14, CTDSPL |
1103 | GO:0051271 | 0.00 | 2.08 | 31.67 | 52 | 134 | negative regulation of cellular component movement | ACTN1, ACVRL1, AGTR2, ALOX15B, ANGPT2, APOH, ARHGAP4, ARHGDIB, BCR, BST2, KRIT1, CD63, CTNNA1, CX3CR1, DCN, DPEP1, DPYSL3, FBLN1, NRG1, HRG, IGFBP3, ILK, SMAD7, SERPINE1, SERPINF1, PFN2, PTEN, PTN, PTPRJ, PTPRR, RAP2A, RAP2B, CCL21, CCL25, SEMA3F, SP100, SRF, STAT3, STC1, NR2F2, WNT11, SEMA3B, CHRD, ADAM15, NRP1, RGN, ITGB1BP1, KLF4, SLIT2, SLC9A3R1, SEMA3E, RNF41 |
1104 | GO:0042306 | 0.00 | 2.07 | 21.27 | 35 | 90 | regulation of protein import into nucleus | AGTR2, ANGPT1, BCL3, BMP4, BMPR1A, CD36, CDH1, CDKN1A, EDA, GNAQ, HCLS1, IGF1, IL10, IL12B, IL18, KPNA1, IPO5, SMAD3, TONSL, PRDX1, PPM1B, PRKCQ, SFRP5, SLC9A1, TRIP6, ZIC1, AKAP1, FZD7, DYRK2, RGS20, TNFSF14, SLC9A3R1, AKAP6, LITAF, NUTF2 |
1105 | GO:0001934 | 0.00 | 2.07 | 28.44 | 47 | 125 | positive regulation of protein phosphorylation | ABL2, ADRA1B, ATP6AP1, C3, CCNB1, CRH, CSNK1D, CTGF, EDNRA, EPHA8, F2, FGA, FLT3LG, FLT4, FSHR, UBE2K, HMGCR, HTR2C, IGF1R, IGFBP3, IL1A, JUN, KDR, KISS1, PRKCE, PSAP, PTEN, RAC1, RAP2A, RAP2B, RYK, S100A7, CCL22, CCL25, XCL1, CX3CL1, SOX9, XCL2, TNFRSF1B, WNT1, CDK2AP1, FZD7, OGT, RPS6KA4, GPR55, RB1CC1, RAD50 |
1106 | GO:0061041 | 0.00 | 2.07 | 17.02 | 28 | 72 | regulation of wound healing | ABAT, ANXA1, ANXA5, APOH, CD36, F2, F2R, F3, F7, FAP, FGA, GP1BA, HMGCR, FOXA2, HRG, KLKB1, KNG1, SMAD3, SERPINE1, PRKCE, PRKCQ, PROC, S100A9, SELP, USF1, VEGFB, VIL1, VTN |
1107 | GO:0048729 | 0.02 | 2.07 | 9.07 | 15 | 39 | tissue morphogenesis | BMPR2, EXT2, EYA2, GNAT2, ITGB1, SMAD1, PRKAR1A, PTN, RPGR, SIX3, STC1, TAL1, CHRD, SLC4A7, IRX5 |
1108 | GO:0099565 | 0.03 | 2.07 | 8.49 | 14 | 36 | chemical synaptic transmission, postsynaptic | TSPO, CHRNB2, CHRNB4, PTK2B, GABRA4, GRID2, GRIN2A, P2RX4, P2RY11, PTEN, SNCA, DGKI, NRXN1, EIF4A3 |
1109 | GO:0045862 | 0.00 | 2.07 | 30.46 | 50 | 130 | positive regulation of proteolysis | C3, CAV3, CCNB1, CDC20, CDC27, CLU, CSNK1D, PTK2B, GPLD1, DNAJB2, IFNG, KLKB1, SMAD7, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, RB1, SKP1, SUMO3, CNTN2, CLEC3B, TNFRSF1B, UBB, SUMO1, CUL3, CUL1, OGT, CDC23, CDC16, RGN, PSMF1, RNF14, DLGAP5, RNF40 |
1110 | GO:0048584 | 0.00 | 2.07 | 18.62 | 31 | 85 | positive regulation of response to stimulus | ADAM10, ALB, BNIP3L, CRH, S1PR1, CXCL3, HMGA1, HSPB1, KCNK2, MGMT, ATXN3, OXCT1, PCNA, PENK, PF4V1, PIP4K2A, RAC2, CXCL6, CXCL5, SETMAR, SNCA, NR2C2, TRPC3, TRPM2, SCG2, PIK3R3, RNF8, RGN, SLIT2, ATG5, CXCL14 |
1111 | GO:0046785 | 0.03 | 2.06 | 8.51 | 14 | 36 | microtubule polymerization | ABL1, ARL2, CAV3, CSNK1D, GOLGA2, RPS3, CLIP1, SGK1, SNCA, TBCD, TUBG1, ZNF207, RANBP9, AKAP9 |
1112 | GO:0046390 | 0.00 | 2.06 | 34.27 | 56 | 145 | ribose phosphate biosynthetic process | ABCA1, ACACB, ADSS, AK1, AK2, AMPD1, AMPD2, APRT, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, AVPR2, CALM3, CRH, DRD3, DRD5, LPAR1, EDNRA, PTK2B, FSHR, GALR1, GCG, GHRHR, GNAS, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GUCY2D, HPRT1, HTR2C, IMPDH1, IMPDH2, LDHC, NTRK2, P2RY11, PALM, PFAS, RAF1, RCVRN, STAT3, UPP1, VIP, VIPR2, WFS1, PAPSS1, AKAP6, GABBR2, AKAP12, GUCA1C, SLC25A13 |
1113 | GO:2001235 | 0.01 | 2.06 | 14.62 | 24 | 62 | positive regulation of apoptotic signaling pathway | AGTR2, APAF1, CTNNA1, CTSH, DAPK3, SMAD3, MAL, PPP2R1A, PPP2R1B, PTEN, TPD52L1, TRAF2, YWHAZ, TP63, DYNLL1, PEA15, TRADD, RIPK1, CRADD, HRK, TNFSF10, TNFRSF10B, TNFRSF10A, PDCD7 |
1114 | GO:0008284 | 0.00 | 2.06 | 94.33 | 152 | 402 | positive regulation of cell proliferation | ABL1, ACVRL1, ADAM10, AGTR2, ANG, ANXA1, BIRC5, ARG1, ARNT, STS, ASCL1, AVPR2, BAD, BCL2L1, BMI1, BMPR1A, BMPR2, CAPN1, CAV3, RUNX2, CD3E, CD4, CD6, CD28, CD86, CD59, CDC20, CDK2, CDK4, CDK6, CDKN1A, CDX2, CHRM1, CHRNB2, CLU, CCR3, CRH, CRKL, CSF1R, CSNK2A1, CTF1, CTGF, CTSH, CX3CR1, DLX5, DPP4, DRD3, ECM1, EDNRA, EFNB1, EGR3, EGR4, EIF5A, EMP2, ETS1, F2, F2R, F3, PTK2B, FBLN1, EFEMP1, FGF3, FGF4, FGF7, FGFR3, FLT3, FLT3LG, FLT4, FSHB, GDF9, B4GALT1, GHRHR, HCLS1, HGF, NR4A1, HMX2, HOXC10, HSF4, IFNG, IGF1R, IGF2, IHH, IL2RA, IL12B, IL12RB2, IL18, ILK, INS, ISL1, ITGAV, ITGB1, KDR, KIT, LTF, KITLG, YBX1, NTRK2, NTRK3, PAX3, PRKAA1, PRKD1, PRKCQ, PTEN, PTK2, PTN, PTPN6, PURA, RAC2, RAD51B, RARA, RARB, REG1A, RSU1, S100A13, TSPAN31, SCN5A, CXCL5, XCL1, SHMT2, SMARCD3, SOX9, SOX10, SOX11, SRPK2, STAT3, ADAM17, TTK, TNFSF4, VEGFB, VIP, WNT1, CNBP, ZNF16, SCG2, FOSL1, FZD7, CUL4A, CUL3, TP63, AKR1C3, CHRD, SERPINB7, TNFSF9, RIPK2, NRP2, NRP1, CCPG1, ITGB1BP1, GLP2R, GAB2, FGFBP1, PDCD6 |
1115 | GO:0006959 | 0.00 | 2.06 | 21.98 | 36 | 93 | humoral immune response | ANG, APP, KLK3, BCL3, BST2, C3, C7, CD28, CD37, CD59, CLU, CR2, DMBT1, FAU, FCER2, FCN2, FGA, CFHR1, HPX, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, RBPJ, LTF, CFP, PTPN6, RPL39, SLPI, VIP, VTN, HIST2H2BE, EXO1 |
1116 | GO:0001894 | 0.01 | 2.06 | 13.39 | 22 | 57 | tissue homeostasis | ABCA4, ACTB, ALB, BARD1, BBS4, CLCN3, COL9A1, CTGF, CTSH, ERCC6, FGF7, GNAS, HSPB1, ITGB1, KCNJ1, KDR, LTF, P2RX4, PRDX1, SFTPD, TULP1, CLRN1 |
1117 | GO:0033047 | 0.01 | 2.06 | 11.58 | 19 | 49 | regulation of mitotic sister chromatid segregation | ATRX, BUB1B, CCNB1, CDC20, CDC27, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, PTEN, RB1, TTK, ZNF207, CUL3, CDC23, CDC16, ZW10, DLGAP5 |
1118 | GO:0050886 | 0.01 | 2.06 | 11.58 | 19 | 49 | endocrine process | AGTR1, AGTR2, AVPR1B, AVPR2, CRH, CRHBP, CYBA, ACE, DRD3, DRD5, F2R, GALR1, GDF9, INHA, KISS1, OXTR, PCSK5, FZD4, ATP6AP2 |
1119 | GO:0061564 | 0.00 | 2.05 | 100.89 | 162 | 428 | axon development | ABL1, ABL2, ACTB, ADAM10, ANGPT1, APP, ARAF, ARHGAP4, BMPR2, CACNA1A, CACNB4, CALM3, CAMK2A, CD72, CHN1, CHRNB2, AP2S1, CNP, CNR1, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2RB, CSNK2A1, CSNK2A2, DCC, DLG3, DLX5, DNM1, DNM2, DPYSL3, EPYC, DUSP5, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EPHA2, CTTN, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, ETV4, FGF3, FGF4, FGF7, FGFR3, FYN, GDI1, GFRA1, GOLGA4, GRB2, GRIN2A, NRG1, IL2RA, ILK, ITGA1, ITGA5, ITGA9, ITGAV, ITGB1, KIF5A, KIT, LIMK1, MARK3, KITLG, NRCAM, NTRK2, NTN3, OTX2, PPP5C, PRKCQ, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTK2, PTPRA, RAC1, RAC2, RAF1, RASA2, RNF6, RPL24, RPS6KA1, RYK, SCN5A, SEMA3F, SHC1, SOS2, SRF, CNTN2, TBCE, TOP2B, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, SEMA3B, FGF23, RND2, USP9X, PICALM, CUL3, CNTNAP1, KLF7, UNC5C, NUMB, PEA15, NRP2, NRP1, ARHGEF7, PHOX2B, RPS6KA4, ARHGEF1, SLIT2, NRXN3, NRXN1, PSMF1, NRG2, AATK, FEZ2, RAPGEF2, SEMA3E, ARHGEF11, RBX1, RANBP9, ARPC5, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, PSME3, PSMD14 |
1120 | GO:0042592 | 0.00 | 2.05 | 49.47 | 81 | 220 | homeostatic process | ABCA4, ACACB, ACTB, ADAR, ADD1, ALB, AMPD2, ANG, AXL, BARD1, BBS4, TNFRSF17, KRIT1, CD7, CLCN6, TPP1, CLNS1A, COL9A1, CTGF, CTSK, CXADR, EMX1, ERCC6, FEN1, FLT3, GAA, GPX1, HCLS1, HSPB1, IFNG, IHH, IL1A, IL1RN, INHA, KCNJ1, KCNN4, KIT, SMAD1, PRDX1, PCNA, PDE4B, PRIM2, RAC1, RAC2, RAC3, RAD51, RAD51D, RAG1, RAG2, RB1, UPF1, RFC3, RFC4, RFC5, RPA2, RPA3, RPS19, SOS2, SOX9, SP1, SP100, TULP1, TYRO3, UBB, CLRN1, TUSC3, HIST1H4I, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, IKBKG, TNFSF14, CCNB2, GPR55, CHST3, CROCC, DCLRE1A, BCL2L11 |
1121 | GO:0030324 | 0.00 | 2.05 | 26.94 | 44 | 114 | lung development | ACVR2B, ARG1, ASCL1, BMP4, BMPR1A, BMPR2, CREB1, CRH, CTGF, CTSH, DHCR7, EIF4E, EP300, FGF7, FGFR3, GATA4, GATA6, GPC3, HHEX, HMGCS2, FOXA2, HSD11B1, IGF1, RBPJ, IL13, KDR, LTA4H, NUMA1, PGR, PTN, SFTPD, SIM2, SOX9, SOX11, SP1, SPARC, SREBF1, SRF, WNT11, AIMP2, NUMB, ADAMTS2, ADAMTSL2, SPRY1 |
1122 | GO:0022898 | 0.00 | 2.05 | 23.87 | 39 | 101 | regulation of transmembrane transporter activity | ATP1A2, FXYD2, BMP4, CACNB4, CALM3, CASQ2, CAV3, CRH, CRHBP, DNM2, DRD3, PTK2B, HRC, INS, KCNJ1, KCNJ11, KCNQ1, KCNS2, NTSR1, PDE4B, FXYD3, PLN, PRKCE, PTAFR, RYR2, S100A1, SCN4B, SLC9A1, SUMO1, KCNAB1, RIPK1, RGN, SLC9A3R1, NRXN1, GSTO1, AKAP7, AKAP6, OXSR1, AKAP9 |
1123 | GO:2001251 | 0.00 | 2.05 | 17.72 | 29 | 75 | negative regulation of chromosome organization | ATRX, BUB1B, CCNB1, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DNMT1, DNMT3B, DUSP1, ERCC4, HMGA1, HNRNPC, JARID2, PHF2, SET, SETMAR, SNCA, TAF7, TTK, XRCC5, ZNF207, CDC23, CDC16, ZW10, ATG5, KDM4A, RAD50 |
1124 | GO:0021879 | 0.04 | 2.05 | 7.33 | 12 | 31 | forebrain neuron differentiation | ASCL1, CSF1R, GNAQ, OGDH, RAC1, RAC3, SALL1, CNTN2, UBB, NRP1, SLIT2, RAPGEF2 |
1125 | GO:0019221 | 0.00 | 2.05 | 33.05 | 54 | 143 | cytokine-mediated signaling pathway | ANGPT1, AXL, BAD, BBS4, CHAD, CSF1R, CSF2RB, DCN, ECM1, EIF4A1, EIF4E, EIF4G2, F3, FLT3, GP1BA, IFNW1, IL1A, IL1R1, IL1RAP, IL1RN, IL2RA, IL10RA, IL12B, IL12RB2, IL13RA2, IL15RA, IRAK1, IRAK2, KIT, KPNA1, KPNA2, KPNA3, KPNA4, NUP98, PPM1B, PTPRN, RANBP2, STAT3, STAT4, STAT5B, STAT6, UBA7, IL1R2, NUP214, AAAS, EIF4G3, RIPK2, RPS6KA4, IL1RL1, SOCS6, IL27RA, NUP155, NUP93, EIF4A3 |
1126 | GO:0015833 | 0.04 | 2.05 | 7.92 | 13 | 34 | peptide transport | BCL3, EDA, IL10, IL12B, IL18, PRDX1, PPM1B, PRKCQ, SLC15A1, TRIP6, TNFSF14, SLC9A3R1, LITAF |
1127 | GO:0034138 | 0.02 | 2.04 | 10.40 | 17 | 44 | toll-like receptor 3 signaling pathway | BIRC3, CD86, CHUK, CREB1, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, RPS6KA1, SKP1, UBB, UBE2D2, CUL1, IKBKG, RIPK1, RIPK2 |
1128 | GO:0090277 | 0.02 | 2.04 | 10.40 | 17 | 44 | positive regulation of peptide hormone secretion | ABAT, BAD, BLK, CRH, FGA, GCG, GHRHR, GLUD1, GPLD1, FFAR1, INS, ISL1, KISS1, OXCT1, PRKCE, TRPM2, ARHGEF7 |
1129 | GO:0060047 | 0.00 | 2.04 | 18.98 | 31 | 81 | heart contraction | AGTR2, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, CACNA1B, CACNB4, CASQ1, CXADR, ACE, GPX1, IFNG, ITPR1, KCND2, KCND3, KCNJ11, KCNJ14, KCNK3, FXYD3, RYR1, S100A1, SLC8A3, SREBF1, TACR3, TRPC1, KCNK6, ATG5, ABCC9, AKAP9, IRX5 |
1130 | GO:0001657 | 0.01 | 2.04 | 13.47 | 22 | 57 | ureteric bud development | AGTR2, ARG2, BMP4, CAT, CD44, GPC3, ILK, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, PSPN, RARA, RARB, SALL1, SDC4, SOX9, WNT1, WNT11, SLIT2, SPRY1 |
1131 | GO:0072163 | 0.01 | 2.04 | 13.47 | 22 | 57 | mesonephric epithelium development | AGTR2, ARG2, BMP4, CAT, CD44, GPC3, ILK, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, PSPN, RARA, RARB, SALL1, SDC4, SOX9, WNT1, WNT11, SLIT2, SPRY1 |
1132 | GO:0006954 | 0.00 | 2.04 | 51.22 | 83 | 219 | inflammatory response | AGTR2, ANXA1, BIRC3, XIAP, ASS1, AXL, C7, CASP5, TNFRSF8, CD59, ADGRE5, CDO1, CHUK, CCR3, CRH, CRHBP, CRP, CSF1R, CYBA, ECM1, F2, F3, FGA, B4GALT1, XCR1, CXCL3, HP, HRH1, IFI16, IFNA2, IL1R1, IL1RAP, IL13, IRAK2, ITIH4, KIT, KNG1, LTA4H, SMAD1, NTRK2, OLR1, ORM2, P2RX1, P2RX7, PF4V1, CFP, PRCP, PRKD1, PRKCQ, PSMA6, PTAFR, PTGDR, PTGS1, RAC1, RXRA, SAA4, CCL21, CCL22, CCL25, CXCL6, CXCL5, SELE, SELP, SP100, STAT3, TP73, SCGB1A1, TRPV1, VTN, SCG2, ATRN, TPST1, IKBKG, RIPK2, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, RPS6KA4, CD163, TRIL, NR1D2, CHST4 |
1133 | GO:1902533 | 0.00 | 2.04 | 76.29 | 123 | 330 | positive regulation of intracellular signal transduction | ADRA1B, ALK, ARAF, ATP6AP1, ATR, BMP4, C3, CALM3, CAMK2A, CD3E, CD4, CD8A, CD44, CRKL, CSF2RB, CSPG4, CTGF, DDX5, DUSP5, EDNRA, EFNA1, EPHA8, ERCC6, FGA, FGF3, FGF4, FGF7, FLT4, FPR1, GCG, GNAS, GNG3, GRB2, RAPGEF1, GRIN2A, GRM1, HIC1, HMGCR, HTR2C, ICAM1, IGFBP3, IL2RA, IRAK2, ITGA1, ITGB1, JUN, KISS1, MARK3, KITLG, MAP3K11, NTRK3, P2RX3, P2RX4, P2RX5, P2RX7, PRKAA1, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTPRA, RAC1, RAF1, RASA2, RHEB, RYK, S100A7, CCL22, CCL25, XCL1, CX3CL1, SHC1, SLC9A1, SLC12A1, SOS2, SOX11, XCL2, TNFRSF1B, TPD52L1, WNT11, FZD5, ARHGEF5, SHOC2, FGF23, FZD4, FZD7, FZD8, CUL3, PDE5A, PEA15, TNFRSF10A, NRP1, DGKI, GPR55, GSTO1, AKAP6, PSMF1, NRG2, AKAP12, TRAF4, RAPGEF2, ZEB2, TNFSF15, RBX1, AKAP9, RASA4, PSME3, PSMD14 |
1134 | GO:0031327 | 0.03 | 2.04 | 9.13 | 15 | 40 | negative regulation of cellular biosynthetic process | LPAR1, EDNRA, GALR1, GHSR, INHA, INS, INSIG1, PALM, PRKAA1, SFTPD, AKR1C3, AKAP6, GABBR2, RAPGEF2, PRG4 |
1135 | GO:0050804 | 0.00 | 2.04 | 30.16 | 49 | 128 | modulation of synaptic transmission | ABAT, ARF1, ATP2B2, BCHE, CACNA1A, CAMK2A, CDC20, CHRNB2, CHRNB4, CREB1, CRH, CTNND2, CX3CR1, DBI, DNM1, DRD5, EGR2, GNAI1, GRIA1, GRIN2A, HRH1, IFNG, KCNJ10, KISS1, KIT, NTSR1, P2RX3, PFN2, SEPT5, PRKCE, PTEN, PTN, RAB5A, RARA, SLC8A3, SNAP25, SRF, STAU1, SYN1, SYP, CNTN2, SYN3, SYNJ1, PICK1, RIN1, SNCAIP, RAPGEF2, RIMS2, EIF4A3 |
1136 | GO:0006939 | 0.03 | 2.03 | 9.19 | 15 | 39 | smooth muscle contraction | ATP1A2, CHRM1, CHRNB2, CHRNB4, CNN1, DAPK3, EDNRA, FLT1, GHSR, KNG1, P2RX1, P2RX3, SMTN, TNNI3, TRPV1 |
1137 | GO:0000187 | 0.01 | 2.03 | 15.36 | 25 | 65 | activation of MAPK activity | ALK, CSPG4, DUSP5, LPAR1, EFNA1, ERCC6, FPR1, GNG3, GRM1, HGF, IRAK1, IRAK2, ITGA1, KIT, MAP3K11, NTRK3, P2RX7, PRKAA1, SHC1, TP73, UBB, IKBKG, PEA15, RIPK1, RIPK2 |
1138 | GO:0006323 | 0.00 | 2.03 | 23.40 | 38 | 99 | DNA packaging | ATRX, CCNB1, CENPA, CENPI, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, HIST1H1A, HMGA1, CHMP1A, SET, SOX9, TOP2A, TSPY1, CHAF1B, HIST1H4I, HIST1H2BL, HIST1H2BN, HIST1H2BM, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, HAT1, RUVBL1, HIST1H3F, SMC4 |
1139 | GO:0044033 | 0.00 | 2.03 | 28.36 | 46 | 120 | multi-organism metabolic process | EP300, ERCC3, FAU, JUN, NUP98, RANBP2, REST, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, SMARCA4, SP1, SP100, TRIM21, SSRP1, TOP2A, TSG101, UBB, USF1, NUP214, AAAS, RPL14, CTDP1, RPL23, ATG5, NUP155, NUP93 |
1140 | GO:0031532 | 0.01 | 2.03 | 12.29 | 20 | 52 | actin cytoskeleton reorganization | ABL1, ABL2, ANXA1, CSF1R, CXADR, DAPK3, S1PR1, CTTN, PTK2B, FGF7, HCLS1, INSRR, KIT, NTRK3, RALA, RAP2A, S100A9, SHC1, CDC42BPB, SEMA3E |
1141 | GO:0045995 | 0.01 | 2.03 | 12.29 | 20 | 52 | regulation of embryonic development | BMP4, BMPR1A, CDX2, E4F1, FZD2, FOXA2, IGF1, IL1RN, LAMA3, LAMA4, OTX2, PAX3, PRKACB, SNAI1, NR2C2, TULP3, WNT1, FZD7, KLF4, RBM19 |
1142 | GO:0006950 | 0.01 | 2.03 | 12.58 | 21 | 62 | response to stress | ABCA1, ACADS, ADH5, NR0B1, CDH8, CIRBP, CPS1, GCG, GCGR, HSPA4, IMPDH1, KCNJ11, SMAD6, SMAD7, OXCT1, OXTR, P2RX4, MANF, SNN, ZNF516, EIF1 |
1143 | GO:0046823 | 0.03 | 2.03 | 9.22 | 15 | 39 | negative regulation of nucleocytoplasmic transport | ANGPT1, BARD1, CD36, IL10, TONSL, PPM1B, RANGAP1, SFRP5, SP100, TRIP6, AKAP1, DYRK2, TNFSF14, SLC9A3R1, LITAF |
1144 | GO:0051098 | 0.00 | 2.03 | 32.14 | 52 | 136 | regulation of binding | ABL1, ABL2, ADD1, ANGPT1, APLP2, APP, ATR, BAX, BCL3, BMP4, KRIT1, EP300, EPB41, GCG, KAT2A, GOLGA2, NRG1, IFI16, IFIT1, IGF1, IL10, ISL1, ITGA4, JUN, LRPAP1, SMAD3, PLN, PEX19, RAN, RAP1GAP, RARA, RFNG, SLPI, SMARCD3, SOX11, SP100, TRAF2, SUMO1, VTN, ADAM15, NRP1, ARHGEF7, TNFSF18, AURKB, CCPG1, ITGB1BP1, KLF4, HAND1, EIF2AK3, TRAF4, RAPGEF2, EIF4A3 |
1145 | GO:1901698 | 0.02 | 2.02 | 9.72 | 16 | 44 | response to nitrogen compound | ADAR, ATRX, DDX1, IFIT1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, KCNJ8, SMAD1, SMAD3, STAT6, TNFSF4, DDX21 |
1146 | GO:0019220 | 0.00 | 2.02 | 20.79 | 34 | 93 | regulation of phosphate metabolic process | APLP2, APP, ARR3, BARD1, CCNE1, CDC25A, CDC25C, CDK4, CKS1B, EPHA2, EPHB1, HRC, HRG, PRDX1, PGAM1, PPP2R1B, PPP2R2A, PPP2R5D, RAC2, RAD51, RBL2, SET, STYX, HSP90B1, TSC1, TSG101, UVRAG, IKBKAP, DIRAS3, EIF2AK3, SMG7, NUAK1, ATP6AP2, RNF41 |
1147 | GO:0030814 | 0.01 | 2.02 | 14.18 | 23 | 60 | regulation of cAMP metabolic process | ABCA1, AVPR2, CALM3, CRH, DRD3, DRD5, LPAR1, EDNRA, FSHR, GALR1, GCG, GHRHR, GNAS, NTRK2, P2RY11, PALM, RAF1, VIP, VIPR2, WFS1, AKAP6, GABBR2, AKAP12 |
1148 | GO:0043123 | 0.00 | 2.02 | 24.11 | 39 | 102 | positive regulation of I-kappaB kinase/NF-kappaB signaling | ABL1, ABL2, BIRC3, BST2, CD36, CHUK, CTH, ECM1, EDA, LPAR1, F2R, FYN, IL1A, IL12B, IL18, IRAK1, LTF, PPP5C, PRKCE, PRKD1, PRKCQ, S100A4, S100A12, S100A13, CCL21, SLC20A1, TNFRSF1A, TRAF2, TRIP6, UBB, TRIM25, IKBKG, TRADD, RIPK1, TNFSF14, TNFSF10, RIPK2, TNFRSF10B, LITAF |
1149 | GO:1903322 | 0.00 | 2.02 | 30.96 | 50 | 131 | positive regulation of protein modification by small protein conjugation or removal | ANGPT1, BIRC3, XIAP, ARNT, AVPR2, BMI1, CAV3, CCNB1, CDC20, CDC27, CLU, PTK2B, FGFR3, DNAJB2, SMAD7, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, SKP1, SUMO3, UBB, UBE2L3, UBE3A, WFS1, AIMP2, CUL1, CDC14B, CDC23, RIPK2, CDC16, PSMF1, RNF40, PSME3, PSMD14 |
1150 | GO:0035264 | 0.00 | 2.02 | 16.04 | 26 | 68 | multicellular organism growth | ADD1, APP, ATRX, BRCA2, DHCR7, DRD3, EN1, ERCC6, G6PC, KAT2A, GNAS, GPD2, HHEX, IGF1, IHH, LLGL2, RARA, RARB, RBBP6, STIL, SLC12A2, STAT3, KDM6A, XPA, XRCC2, ATRN |
1151 | GO:0007169 | 0.00 | 2.02 | 30.13 | 49 | 133 | transmembrane receptor protein tyrosine kinase signaling pathway | ABL1, ABL2, ALK, ANGPT2, APLP2, APP, BCR, BLK, BTK, CD3E, CD4, CD7, CD8A, CSF1R, CSH1, CSPG4, DOK1, EPS15, F3, F7, EFEMP1, FGR, GFRA1, GH2, GHRHR, GHSR, GRB7, HGF, IGF1, IGFBP3, IGFBP6, INSRR, ITGA1, NTF4, PTPN6, PTPRJ, PTPRR, SNCA, SOX9, STAT5B, VIL1, WNT1, DOK2, ANGPTL1, REPS2, SLC9A3R1, EIF2AK3, GAB2, STAM2 |
1152 | GO:0030316 | 0.02 | 2.01 | 11.11 | 18 | 47 | osteoclast differentiation | ATP6AP1, BGLAP, CHUK, CREB1, CSF1R, EPHA2, FSHB, FSHR, GPC3, GNAS, IFNG, IL12B, LTF, KLF10, TYROBP, INPP4B, GPR55, GAB2 |
1153 | GO:0034763 | 0.02 | 2.01 | 11.11 | 18 | 47 | negative regulation of transmembrane transport | ATP1A2, CALM3, CASQ2, CAV3, DRD3, KCNH2, KCNQ1, NTSR1, OAZ1, OAZ2, PLN, PRKCE, SPINK1, SUMO1, KCNAB1, SLC9A3R1, GSTO1, OXSR1 |
1154 | GO:0009581 | 0.00 | 2.01 | 27.89 | 45 | 118 | detection of external stimulus | ABCA4, ATP2B2, OPN1SW, CACNB4, CALM3, CAV3, AKR1C4, CHRM1, CLPS, CNGA1, COL11A1, EPHB1, GPC4, FYN, OPN1MW, GPC3, GNAQ, GNAT1, GNAT2, GNGT1, GNGT2, GUCA1A, GUCY2F, GUCY2D, IGF1, KCNA1, KIT, NTSR1, PRKCQ, RBP1, RBP2, OPN1LW, RCVRN, RGR, SDC4, SLC12A2, TRPC3, TULP1, TRPV1, AKR1C3, UNC119, GUCA1C, SDC3, PIEZO1, NR2E3 |
1155 | GO:0009126 | 0.00 | 2.01 | 29.78 | 48 | 126 | purine nucleoside monophosphate metabolic process | ADSS, AK1, AK2, ALDOC, AMPD1, AMPD2, APRT, ARNT, ATP1A2, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1B2, ATP6V0A1, BAD, TSPO, COX8A, COX15, CTNS, DLG2, DLG3, ENO2, GAPDH, HPRT1, IGF1, IMPDH1, IMPDH2, INS, LDHC, OGDH, P2RX7, PFAS, PGAM1, PPP2R5D, PRKAA1, PRKAG1, SDHC, SNCA, STAT3, TAZ, UQCRC1, UQCRC2, UQCRH, OGT, SLC25A13 |
1156 | GO:0048667 | 0.00 | 2.01 | 97.05 | 154 | 412 | cell morphogenesis involved in neuron differentiation | ABL1, ACTB, ADAM10, ANGPT1, APP, ARAF, ARHGAP4, ATP2B2, BMPR2, CACNB4, CALM3, CAMK2A, CD72, CHN1, AP2S1, CNP, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2RB, CSNK2A1, CSNK2A2, DCC, DLG3, DLX5, DNM1, DNM2, DPYSL3, EPYC, DUSP5, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EPHA2, CTTN, EPHA5, EPHA8, ETV4, FGF3, FGF4, FGF7, FGFR3, GDI1, GFRA1, GOLGA4, GRB2, GRIN2A, NRG1, IL2RA, ISL1, ITGA1, ITGA5, ITGA9, ITGAV, KIF5A, KIT, LIMK1, MARK3, KITLG, NRCAM, NTRK2, NTRK3, NTN3, OTX2, PPP5C, PRKCQ, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTK2, PTPRA, RAC2, RAF1, RASA2, RB1, RNF6, RPL24, RPS6KA1, RYK, SCN5A, SEMA3F, SHC1, SOS2, SRF, CNTN2, TBCE, TNR, TOP2B, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, CLRN1, SEMA3B, FGF23, RND2, USP9X, CUL3, CNTNAP1, UNC5C, NUMB, PEA15, NRP2, NRP1, ARHGEF7, PHOX2B, RPS6KA4, ARHGEF1, SLIT2, SLC9A3R1, NRXN3, NRXN1, PSMF1, NRG2, AATK, FEZ2, SEMA3E, ARHGEF11, RBX1, RANBP9, ARPC5, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, PSME3, PSMD14 |
1157 | GO:0006725 | 0.02 | 2.01 | 10.95 | 18 | 51 | cellular aromatic compound metabolic process | ABAT, BCHE, CHRNB2, CTRB1, CYP2F1, SARDH, G6PC, GIF, GOT2, GRIN2A, HPX, ABCD4, SHMT2, SLC34A1, SNCB, SRD5A1, TACR3, SNCAIP |
1158 | GO:0052652 | 0.01 | 2.01 | 14.85 | 24 | 63 | cyclic purine nucleotide metabolic process | ABCA1, AMPD2, AVPR2, CALM3, CRH, DRD3, DRD5, LPAR1, EDNRA, FSHR, GALR1, GCG, GHRHR, GNAS, NTRK2, P2RY11, PALM, RAF1, VIP, VIPR2, WFS1, AKAP6, GABBR2, AKAP12 |
1159 | GO:0006112 | 0.00 | 2.01 | 24.81 | 40 | 105 | energy reserve metabolic process | ACACB, ADRA1B, ARL2, CACNA1A, CALM3, CHRM3, CPS1, G6PC, GAA, GCG, GCGR, GNAS, GNG3, GNG10, FFAR1, GYS2, IGF1, IGF2, INS, ITPR1, KCNC2, KCNJ11, KCNS3, PHKA2, PHKB, PHKG1, PPP2R5D, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PYGB, PYGM, SNAP25, SYT5, UBB, DYRK2, EPM2AIP1 |
1160 | GO:0048704 | 0.04 | 2.01 | 8.04 | 13 | 34 | embryonic skeletal system morphogenesis | ALX3, BMP4, RUNX2, COL11A1, GNAS, HOXC11, HOXD9, HOXD10, SMAD3, SOX11, TULP3, EIF4A3, IRX5 |
1161 | GO:2000278 | 0.04 | 2.01 | 8.04 | 13 | 34 | regulation of DNA biosynthetic process | ACVRL1, BMPR2, CDKN1A, DKC1, DUSP1, PTK2B, HGF, KCNK2, NVL, PRKCQ, RGN, AURKB, KLF4 |
1162 | GO:0051668 | 0.01 | 2.01 | 13.00 | 21 | 55 | localization within membrane | ARCN1, ARF1, CD59, COPA, CSNK1D, GOLGA2, GRIA1, INSIG1, MAL, PPP6C, PRKCI, RAB1A, RAC1, RALA, TRAPPC2, CUL3, USO1, VAPB, COPB2, SEC22B, GOSR2 |
1163 | GO:0045089 | 0.00 | 2.01 | 43.01 | 69 | 182 | positive regulation of innate immune response | BIRC3, XIAP, BTK, CALM3, CD86, CD36, CHUK, CREB1, CTSK, CYBA, DMBT1, ELK1, EP300, FYN, UBE2K, HPX, ICAM2, IFI16, IL12B, IRAK1, IRAK2, IRF1, ITGAM, ITPR1, JUN, LTF, PPP2R5D, PRKACB, PRKACG, PRKCE, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PVR, RAF1, RPS6KA1, RPS19, SEC14L1, SKP1, STAT5B, HSP90B1, TYRO3, UBB, UBE2D2, VAV1, CUL1, IKBKG, RIPK1, RIPK2, UBA3, PSMF1, TRIL, NR1H4, PSME3, PSMD14 |
1164 | GO:0002699 | 0.00 | 2.00 | 19.85 | 32 | 84 | positive regulation of immune effector process | ANXA1, C3, CD28, CD86, CD36, CD37, FCER2, FGR, FFAR3, HPX, IFNG, IL12B, IL13, IL13RA2, P2RX7, PTAFR, PVR, RAC2, RARA, RPS19, XCL1, STAT5B, STAT6, STXBP2, TRAF2, TNFSF4, UNG, VAV1, FZD5, VAMP8, RIPK2, GAB2 |
1165 | GO:0043488 | 0.00 | 2.00 | 21.74 | 35 | 92 | regulation of mRNA stability | ZFP36L2, CIRBP, ELAVL1, HNRNPC, HSPB1, YBX1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, UPF1, SET, UBB, SCGB1A1, VIP, YWHAZ, NUP214, ANP32A, KHSRP, PSMF1, PSME3, PSMD14 |
1166 | GO:0022904 | 0.01 | 2.00 | 14.89 | 24 | 63 | respiratory electron transport chain | ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, COX6A1, COX6B1, COX7C, COX8A, COX15, CYC1, SDHA, SDHB, SDHC, SDHD, SNCA, TAZ, UCP1, UQCRC1, UQCRC2, UQCRH, SLC25A12, SLC25A13 |
1167 | GO:0031623 | 0.03 | 2.00 | 9.92 | 16 | 42 | receptor internalization | ANGPT1, ARF1, CAV3, CD9, CD36, CD63, GRB2, GRIA1, ITGB1, RAB5A, SELE, SNCA, CNTN2, PICALM, PICK1, RAMP3 |
1168 | GO:0048705 | 0.02 | 2.00 | 11.78 | 19 | 50 | skeletal system morphogenesis | ACVR2B, BMPR2, CHAD, COL1A1, COL9A1, COMP, DLX5, FGFR3, HOXD8, IDUA, INPPL1, INSIG1, LTF, P2RX7, PEX7, RARA, RARB, STC1, IFT140 |
1169 | GO:0007346 | 0.00 | 2.00 | 50.03 | 80 | 213 | regulation of mitotic cell cycle | ASCL1, ATRX, BCL2L1, BMP4, BUB1B, CDC20, CDC25C, CDC27, CDK2, CDKN1A, CENPE, CENPF, CHEK1, CSNK2A1, CSNK2A2, DAPK3, BRINP1, DUSP1, E4F1, ERCC3, FGFR3, GAS1, SMAD3, FOXO4, OVOL1, CHMP1A, PIM1, PRCC, PRKCQ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTPN6, RPA2, RPA3, RPL24, SETMAR, SKP1, SMARCA4, STK10, ADAM17, DYNLT3, TOP2A, TOP2B, TP73, TTK, UBB, ZNF207, SMC1A, CUL1, TP63, CDC23, CRADD, CDC16, ZW10, SLC9A3R1, PSMF1, MAD2L1BP, SLK, CUL7, OXSR1, SAE1, RAD50, PSME3, PSMD14, CTDSPL |
1170 | GO:0044770 | 0.00 | 2.00 | 37.38 | 60 | 160 | cell cycle phase transition | BACH1, CAMK2A, CCNE1, CDC25A, CDC25C, CDK3, CDK6, CHEK1, CKS1B, CSNK1D, DHFR, DYNC1H1, DNM2, E2F6, EIF4E, EP300, ERCC3, ITGB1, PPP1R12A, PPP1R12B, NUMA1, ORC1, ORC2, ORC4, PCM1, PCNA, PIM1, PPP2R1A, PPP2R2A, PPP6C, PRIM2, PRKAR2B, PRKCQ, PTPN6, RPA3, RPL24, RPS6KB1, RRM2, SIX3, SKP1, ADAM17, TPD52L1, TUBA4A, TUBG1, TYMS, UBE2L3, TUBA1A, CUL2, CUL1, KLF11, PPM1D, SSNA1, DYNLL1, LATS1, CCNB2, CTDP1, MAD2L1BP, CEP135, CKAP5, AKAP9 |
1171 | GO:0098869 | 0.03 | 2.00 | 9.93 | 16 | 42 | cellular oxidant detoxification | ALB, CAT, CD36, DHFR, GPX1, GPX2, GSTZ1, HBA2, HP, PRDX1, PTGS1, S100A9, SEPW1, SOD2, RGN, GSTO1 |
1172 | GO:0072522 | 0.00 | 2.00 | 33.05 | 53 | 140 | purine-containing compound biosynthetic process | ABCA1, ACACB, ADSS, AK1, AK2, AMPD1, AMPD2, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, AVPR2, CALM3, CRH, DRD3, DRD5, LPAR1, EDNRA, PTK2B, FSHR, GALR1, GCG, GHRHR, GNAS, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GUCY2D, HTR2C, IMPDH1, IMPDH2, LDHC, NTRK2, P2RY11, PALM, PFAS, RAF1, RCVRN, STAT3, VIP, VIPR2, WFS1, PAPSS1, AKAP6, GABBR2, AKAP12, GUCA1C, SLC25A13 |
1173 | GO:0010647 | 0.00 | 2.00 | 18.46 | 30 | 83 | positive regulation of cell communication | BLK, BNIP3L, CHRNB2, CHRNB4, CREB1, CRH, CX3CR1, DBI, DNM1, GALR1, GFAP, GLUD1, GPLD1, FFAR1, OXCT1, OXTR, PIP4K2A, PTN, RAB3B, SLC8A3, SNAP25, SNCA, STAU1, SYT1, TNR, TRPM2, VAMP8, SYNJ1, ARHGEF7, ATG5 |
1174 | GO:0030307 | 0.00 | 1.99 | 18.67 | 30 | 79 | positive regulation of cell growth | ADAM10, BMPR2, CSNK2A1, CYBA, EFNA5, EXTL3, F2, PTK2B, GOLGA4, HIST1H1B, NRG1, IGF1, ILK, INS, LIMK1, NTRK3, RPS6KA1, S100A8, S100A9, SGK1, SLC9A1, SRF, SUPV3L1, SYT1, SYT4, ADAM17, RND2, NRP1, AKAP6, RIMS2 |
1175 | GO:0050801 | 0.00 | 1.99 | 62.79 | 100 | 269 | ion homeostasis | ABCA1, ABCB7, ABL2, ADRA1B, ALAS2, ANXA6, XIAP, APLP2, APP, ARF1, ATP1A1, ATP1A3, ATP12A, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP4A, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, AVPR1B, CACNA1A, CACNB4, CD36, CD52, CLCN3, CLN5, CCR3, CCR8, CPS1, CRH, DRD5, S1PR1, LPAR1, FTL, GALR1, GNA15, GNAT2, GNG3, GRINA, GRM1, GTF2I, HEXB, HPX, INS, ITGB1, KCNA1, KCNH2, KCNJ2, KCNJ10, KCNK3, KISS1, LTF, NUBP1, OXTR, P2RY2, P2RY4, PDK4, PRKAA1, PYGM, RHAG, S100A8, S100A9, SCN7A, SCNN1A, SCNN1B, SCNN1G, SCO1, SGK1, SLC4A1, SLC8A3, SLC9A1, SLC9A2, SLC9A3, SLC34A1, STC1, TNNI3, TPT1, HSP90B1, TRPC4, TRPC5, TRPM2, UPK3A, WFS1, FGF23, PICALM, DGAT1, S1PR4, INPP4B, RGN, ATP6V0D1, VAPB, SLC9A3R1, LIPG, ATP6V1G1, ABCB6, SGK2 |
1176 | GO:0006109 | 0.00 | 1.99 | 20.56 | 33 | 87 | regulation of carbohydrate metabolic process | ACACB, ADRA1B, ARNT, BAD, PTK2B, GCG, GCGR, KAT2A, GOLGA2, GPLD1, FOXA2, HRH1, IGF1, IGF2, IGFBP3, INS, NTSR1, P2RX7, PDK4, PGAM1, PRKAA1, PRKAG1, PRKCE, PTAFR, RANBP2, SNCA, STAT3, DYRK2, OGT, RGN, TMEM59, EPM2AIP1, NR1H4 |
1177 | GO:0010906 | 0.02 | 1.99 | 11.82 | 19 | 50 | regulation of glucose metabolic process | ACACB, ADRA1B, BAD, GCG, GCGR, KAT2A, GPLD1, FOXA2, IGF1, IGF2, IGFBP3, INS, PDK4, PGAM1, RANBP2, DYRK2, OGT, RGN, EPM2AIP1 |
1178 | GO:0032231 | 0.02 | 1.99 | 11.82 | 19 | 50 | regulation of actin filament bundle assembly | ARHGAP6, BBS4, CTGF, S1PR1, LPAR1, LIMK1, SMAD3, PFN2, PRKCQ, RAC1, SDC4, SLC9A1, TSC1, VIL1, WNT11, ARHGEF5, ITGB1BP1, BAG4, WASF2 |
1179 | GO:1904591 | 0.02 | 1.99 | 11.82 | 19 | 50 | positive regulation of protein import | BMP4, BMPR1A, CDH1, EDA, HCLS1, IGF1, IL12B, IL18, KPNA1, IPO5, SMAD3, PRKCQ, SLC9A1, TRIP6, ZIC1, ARHGEF5, TNFSF14, AKAP6, NUTF2 |
1180 | GO:0009582 | 0.00 | 1.99 | 28.12 | 45 | 119 | detection of abiotic stimulus | ABCA4, ATP2B2, OPN1SW, CACNB4, CALM3, CAV3, AKR1C4, CHRM1, CLPS, CNGA1, COL11A1, EPHB1, GPC4, FYN, OPN1MW, GPC3, GNAQ, GNAT1, GNAT2, GNGT1, GNGT2, GUCA1A, GUCY2F, GUCY2D, IGF1, KCNA1, KIT, NTSR1, PRKCQ, RBP1, RBP2, OPN1LW, RCVRN, RGR, SDC4, SLC12A2, TRPC3, TULP1, TRPV1, AKR1C3, UNC119, GUCA1C, SDC3, PIEZO1, NR2E3 |
1181 | GO:0003231 | 0.01 | 1.98 | 13.71 | 22 | 58 | cardiac ventricle development | PRDM1, COL11A1, DNM2, FZD2, GATA4, NRG1, RBPJ, ISL1, KCNK2, SMAD6, SMAD7, RXRA, RYR2, SALL1, SCN5A, SMARCD3, SOX11, TNNC1, TNNI3, WNT11, TRIP11, HAND1 |
1182 | GO:0015672 | 0.00 | 1.98 | 85.55 | 135 | 362 | monovalent inorganic cation transport | ABAT, ACACB, ARF1, ATF4, ATP1A1, ATP1A2, ATP1A3, ATP12A, FXYD2, ATP4A, ATP4B, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, CACNA1A, CASQ2, CAV3, CD63, CDK2, CHRNB2, CNGA1, CNR1, COX6A1, COX6B1, COX7A1, COX7C, COX8A, COX15, CPT1B, CPT2, CRH, CYB5A, DNM2, DPP6, DRD3, EDNRA, PTK2B, IL13, KCNA1, KCNA3, KCNA4, KCNC2, KCND2, KCND3, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN4, KCNQ1, KCNS2, KCNS3, P2RX1, P2RX4, P2RX7, PCP4, FXYD3, PRKCE, RAB3B, REST, RHAG, RHCE, RHD, SCN1A, SCN2A, SCN4B, SCN5A, SCN7A, SCN8A, SCNN1A, SCNN1B, SCNN1G, SEC14L1, SGK1, SLC5A2, SLC8A3, SLC9A1, SLC9A2, SLC9A3, SLC10A1, SLC12A1, SLC12A2, SLC13A1, SLC15A1, SLC34A1, SLC20A1, SLC22A1, SLC22A3, SLC22A2, SLC22A5, SNCA, TAF7, TRPM2, TSC1, SUMO1, UCP1, UQCRC1, UQCRH, VIP, KCNAB1, VAMP8, SLC5A6, SLC13A2, ATP6V0D1, KCNAB3, SLC9A3R1, KCNK6, AKAP7, AKAP6, SLC4A7, ATP6V1G1, OXSR1, SLC12A6, HCN4, ABCC9, SGK2, AKAP9, KCNMB2 |
1183 | GO:0007507 | 0.00 | 1.98 | 32.52 | 52 | 139 | heart development | ACACB, ACVR2B, ADRA1B, APLNR, BBS4, CRKL, VCAN, EDNRA, EFNA1, EP300, FBN1, FZD2, GAA, GNAQ, HHEX, IHH, ILK, ITGA4, JUN, KCNJ8, SMAD3, NTRK3, OXCT1, OXTR, PAM, PAX3, PCNA, PSKH1, PTK2, PTN, PTPRJ, RAF1, RYR1, SALL1, SCN5A, SHC1, STIL, SMARCD3, SNAI1, SOX11, SPARC, KDM6A, WNT11, KCNAB1, ADAM19, ADAM15, CDKL1, BAZ1B, TRIP11, IFT140, RB1CC1, COL4A3BP |
1184 | GO:0009719 | 0.00 | 1.98 | 29.61 | 48 | 138 | response to endogenous stimulus | ABCA1, APAF1, CAV3, CBL, CCNC, CCNT2, CD9, CD28, CD86, CD36, CD44, CDK8, CSNK1D, CX3CR1, EGR3, FSHB, FUT8, KAT2A, ONECUT1, HPGD, IL1R1, ING2, ITPR1, LTBP2, SMAD3, OTX2, SERPINE1, PPP2CB, PPP2R1A, RAP1GAP, RPS3, RPS6KB2, XCL1, SP1, CLEC3B, VAV1, VIL1, SHOC2, STK16, ITGB1BP1, ZFYVE9, ONECUT2, GDF15, BAG4, ADAMTSL2, EIF4A3, FGFBP1, SPRY1 |
1185 | GO:0006928 | 0.00 | 1.98 | 154.98 | 241 | 681 | movement of cell or subcellular component | ACTB, AGTR1, ANG, APP, ARAF, ASCL1, ASTN1, RERE, KIF1A, AXL, BAX, BICD1, DST, BSG, TSPO, CACNB4, CALM3, CAMK2A, CAV3, CD9, CD44, CD58, CD72, ADGRE5, CD151, CENPE, CHN1, AP2S1, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF2RB, CSNK2A1, CSNK2A2, VCAN, CSPG4, CTGF, CXADR, DBH, DCC, DLG3, DLX5, DNM1, DNAH8, DYNC1H1, DPP4, DUSP5, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EGR3, CTTN, EMX2, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, ERG, ETV4, F2, FAP, FGF3, FGFR3, FPR1, FPR3, FUT8, FYN, GFRA1, GPM6A, GPR15, GPX1, GRB2, GRIN2A, HIST1H1T, HEXB, NR4A1, HRH1, IL2RA, IL10, IL12B, IL13, ING2, ISL1, ITGA1, ITGA9, ITGAM, KCNH2, KCNQ1, KIF5A, KIF25, KRT2, LDHC, LIMK1, MARK3, SMCP, MYO1B, NRCAM, NTRK2, NTN3, OGDH, OLR1, OPA1, OTX2, PALM, PAX3, PCM1, PEX7, PEX13, SERPINB5, SERPINI2, PIK3C2B, PPP5C, PRKCI, PRKCQ, PSPN, PROC, PSG2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTPN6, PTPRA, RAB1A, RAB6A, RASA2, RFX3, RPGR, RPL24, RPS6KA1, RYK, S100A2, S100A8, S100A9, S100A12, SAA4, SCN4B, SCNN1B, CCL22, SELL, SELPLG, SFTPD, SHC1, SIX3, SLC9A1, FSCN1, SORD, SOS2, SOX10, SPOCK1, XCL2, CNTN2, NR2F1, TNNC2, TNNI2, TNNI3, TNR, TOP2B, TPM2, TRPC1, TRPC3, TRPC4, TRPC5, TYRO3, TYROBP, UBB, CLRN1, VAV1, VIM, DNALI1, SCG2, ARHGEF5, FGF23, SLC7A5, USP9X, USP9Y, UXT, CUL3, SORBS2, CNTNAP1, AP3B1, KLF7, SSNA1, DYNLL1, PEA15, VNN2, PHOX2B, AP3D1, RPS6KA4, DOK2, NRXN3, KIF3B, NRXN1, PSMF1, NRG2, CDC42BPB, NUP155, FEZ2, SDC3, IFT140, DLGAP5, ARHGEF11, ZEB2, GAB2, KIAA0319, RBX1, RANBP9, ARPC5, ARPC1B, ACTR2, ARPC2, KIF20A, AKAP9, ABI2, RASA4, WASF2, CHST4, PSME3, PSMD14 |
1186 | GO:0006413 | 0.00 | 1.98 | 18.12 | 29 | 77 | translational initiation | EIF1AX, EIF4E, FAU, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, DDX3Y, EIF2S2, RPL14, RPL23 |
1187 | GO:0030071 | 0.04 | 1.98 | 8.73 | 14 | 37 | regulation of mitotic metaphase/anaphase transition | BUB1B, CCNB1, CDC20, CDC27, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, TTK, ZNF207, CDC23, CDC16, ZW10 |
1188 | GO:1901362 | 0.00 | 1.97 | 21.63 | 35 | 100 | organic cyclic compound biosynthetic process | ALAD, ALAS2, ASIP, ATP1A1, TSPO, AKR1C4, COX15, CPOX, CPS1, CTNS, CYP3A4, CYP8B1, CYP11B1, DBH, DHCR7, CYB5R3, FDFT1, FDPS, HMBS, HMGCR, HMGCS2, HSD11B1, IDO1, OAT, PAH, PYCR1, QDPR, SRD5A1, TRPC1, TYR, UROS, AKR1C3, ALDH4A1, RAPGEF2, ABCB6 |
1189 | GO:0006353 | 0.04 | 1.97 | 8.74 | 14 | 37 | DNA-templated transcription, termination | CSTF3, ERCC3, MAZ, SRSF1, SRSF5, SRSF7, SNRPE, SNRPF, TBP, TTF1, SRSF9, TAF1B, TAF1A, RBM8A |
1190 | GO:0043462 | 0.04 | 1.97 | 8.74 | 14 | 37 | regulation of ATPase activity | CNN3, DNM2, LTF, PFN2, PLN, RAB4A, RYR2, SETMAR, SNRNP70, TNNC1, TNNI3, TPM2, SUMO1, RGN |
1191 | GO:0048144 | 0.04 | 1.97 | 8.74 | 14 | 37 | fibroblast proliferation | AGTR2, BAX, BMI1, CCNB1, CDK4, CDK6, CDKN1A, CREB1, EDNRA, FBLN1, IGF1, IL13, JUN, WNT1 |
1192 | GO:0038096 | 0.02 | 1.97 | 10.63 | 17 | 45 | Fc-gamma receptor signaling pathway involved in phagocytosis | ABL1, ACTB, CD3G, FGR, FYN, GRB2, ITPR1, LIMK1, PRKCE, PTK2, RAC1, VAV1, ARPC5, ARPC1B, ACTR2, ARPC2, WASF2 |
1193 | GO:0003206 | 0.01 | 1.97 | 12.53 | 20 | 53 | cardiac chamber morphogenesis | CAV3, COL11A1, FZD2, GATA4, GATA6, NRG1, RBPJ, ISL1, SMAD7, RARA, RARB, RXRA, RYR2, SMARCD3, SOX11, SRF, TNNC1, TNNI3, WNT11, HAND1 |
1194 | GO:0009179 | 0.01 | 1.97 | 12.53 | 20 | 53 | purine ribonucleoside diphosphate metabolic process | AK1, AK2, ALDOC, ARNT, BAD, ENTPD2, DLG2, DLG3, ENO2, GAPDH, IGF1, INS, OGDH, P2RX7, PGAM1, PPP2R5D, PRKAA1, PRKAG1, STAT3, OGT |
1195 | GO:0072091 | 0.01 | 1.97 | 12.53 | 20 | 53 | regulation of stem cell proliferation | BMP4, BMPR1A, CTNNA1, CX3CR1, ACE, FBLN1, IHH, KDR, KITLG, OVOL1, PTN, CX3CL1, SIX3, SMARCD3, SOX9, SOX10, SOX11, WNT11, TP63, CHRD |
1196 | GO:0045766 | 0.01 | 1.97 | 16.31 | 26 | 69 | positive regulation of angiogenesis | ACVRL1, ANGPT2, ANXA3, C3, CCR3, CTSH, CX3CR1, ECM1, ETS1, F3, PTK2B, FLT1, GATA4, GATA6, HGF, HSPB1, IL1A, ISL1, ITGA5, KDR, SERPINE1, PRKD1, PTGIS, CX3CL1, VEGFB, PDCD6 |
1197 | GO:0050866 | 0.00 | 1.97 | 20.09 | 32 | 85 | negative regulation of cell activation | ABAT, ANXA1, AXL, BCR, PRDM1, BMP4, BPI, CBLB, CD37, CNR1, CTLA4, F2, FLT3, IFNA2, IHH, IL2RA, IL10, IL13RA2, IDO1, INHA, IRF1, PRKAR1A, PTPN6, XCL1, SFTPD, SOX11, TNFSF4, TYRO3, SCGB1A1, PDE5A, TNFSF18, SOCS6 |
1198 | GO:0048812 | 0.00 | 1.96 | 101.76 | 159 | 432 | neuron projection morphogenesis | ABL1, ACTB, ADAM10, ANGPT1, APP, ARAF, ARHGAP4, BMPR2, CACNB4, CALM3, CAMK2A, CD72, CHN1, AP2S1, CLU, CNP, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2RB, CSNK2A1, CSNK2A2, DCC, DLG3, DLX5, DNM1, DNM2, DPYSL3, EPYC, DUSP5, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EPHA2, EMX1, CTTN, EPHA5, EPHA8, ETV4, FGF3, FGF4, FGF7, FGFR3, GDI1, GFRA1, GOLGA4, GPM6A, GRB2, GRIN2A, NRG1, IL2RA, ISL1, ITGA1, ITGA5, ITGA9, ITGAV, KIF5A, KIT, LIMK1, MARK3, KITLG, NRCAM, NTF4, NTRK2, NTRK3, NTN3, OTX2, PPP5C, PRKCQ, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTK2, PTPRA, RAC2, RAF1, RASA2, RNF6, RPL24, RPS6KA1, RYK, SCN5A, SEMA3F, SHC1, SOS2, SRF, SYT1, SYT4, CNTN2, TBCE, DYNLT1, TNR, TOP2B, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, SEMA3B, FGF23, RND2, USP9X, CUL3, CNTNAP1, GAS7, UNC5C, NUMB, PEA15, NRP2, NRP1, ARHGEF7, PHOX2B, RPS6KA4, ARHGEF1, SLIT2, NRXN3, NRXN1, PSMF1, NRG2, AATK, FEZ2, RIMS2, SEMA3E, ARHGEF11, RBX1, RANBP9, ARPC5, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, PSME3, PSMD14 |
1199 | GO:0032101 | 0.00 | 1.96 | 48.59 | 77 | 209 | regulation of response to external stimulus | ACTL6A, ADAM10, AGTR1, ANXA1, XIAP, ATP6V0A1, BMPR2, BNIP3L, C3, C7, CASP5, CD6, CD36, CD59, CNR1, CSNK2A2, CTSK, CYBA, DCN, S1PR1, LPAR1, EDNRA, CTTN, F2R, F3, F7, PTK2B, FGF4, KAT2A, FFAR3, CXCL3, FOXA2, HSPB1, IL1R1, IL18, IDO1, KDR, NTRK3, PF4V1, CFP, PIP4K2A, PRKD1, PSMA6, RAC2, S100A7, S100A8, S100A9, S100A12, CCL21, CXCL6, CXCL5, XCL1, CX3CL1, SELE, SELP, SREBF1, STAT5B, XCL2, ADAM17, TNFSF4, SCGB1A1, VEGFB, ZBTB17, FZD5, SCG2, RUVBL1, VAMP8, TNFSF14, TNFSF18, USP14, IL1RL1, RAB33A, ATG5, CXCL14, CLOCK, NR1D2, HDAC6 |
1200 | GO:0010604 | 0.00 | 1.96 | 143.81 | 223 | 642 | positive regulation of macromolecule metabolic process | ABL1, ABL2, ACVR2B, AGTR1, ANG, ANGPT1, APAF1, BIRC3, XIAP, ARAF, ATP6AP1, ATR, BAD, BARD1, BAX, BMI1, BMP1, BMP8B, BOK, ZFP36L2, CALM3, CASP9, CAV3, CBLB, CD4, TNFRSF8, CD36, CD63, CDC20, CDC27, CDKN1A, CENPE, COL4A3, CRKL, CSF1R, CSF2RB, CSNK1D, CSNK2A1, CSPG4, CTF1, ACE, DKC1, DUSP5, LPAR1, EDNRA, EFNA1, EFNA5, EMP2, EPHA8, F2, F3, FCER2, FGA, FGF3, FGFR3, FLT1, FLT3, FLT3LG, FLT4, FPR1, FSHR, FYN, GDF9, GPC3, GNG3, GOLGA2, GPLD1, GRB2, RAPGEF1, GRIN2A, GRM1, HIST1H1B, HIP1, UBE2K, HMGCR, HPX, DNAJB2, HSPB1, HTR2C, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGF1R, IGFBP3, IL2RA, IL12B, IL13, INHA, ITGA1, ITGA5, ITGB1, JARID2, KDR, KISS1, MARK3, KITLG, MGMT, ATXN3, MAP3K11, NVL, OAZ1, OAZ2, P2RX1, PCNA, PCOLCE, PFN2, PIM1, PPP5C, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMB1, PSMB2, PSMB4, PSMD2, PSMD3, PSMD4, PSMD7, PTK2, PTPRA, RAB1A, RAC1, RAD51, RAP2A, RAP2B, RASA2, UPF1, RYK, S100A7, CCL21, CCL22, CCL25, XCL1, CX3CL1, SDC4, SELE, SETMAR, SHC1, STIL, SKP1, SUMO3, SNCA, STK10, SUPV3L1, XCL2, ADAM17, NR2F1, TNFRSF1B, TPD52L1, TTK, TNFSF4, UBE2L3, SUMO1, UNG, VEGFB, VIP, VTN, WFS1, AIMP2, CDK2AP1, BCAR3, CUL3, CUL1, CDC14B, PDE5A, PEA15, CDC23, SERPINB7, EED, CRADD, TNFSF10, TNFRSF18, TNFRSF10B, TNFRSF10A, NRP1, CDC16, RNF8, UNC119, RGN, LATS1, AURKB, VAPB, GPR55, PICK1, AKAP6, PSMF1, GDF15, BAG4, NRG2, SEC22B, GTPBP1, TRAF4, RAPGEF2, SLK, ATG13, DLGAP5, RNF40, RB1CC1, OXSR1, TNFSF15, RBX1, CASP8AP2, HDAC6, PDCD6, BCL2L11, RAD50, AKAP9, RASA4, PSME3, PSMD14, RAMP3 |
1201 | GO:0048732 | 0.00 | 1.96 | 18.80 | 30 | 81 | gland development | ABL1, APRT, ASCL1, ATP2B2, BRCA2, TSPO, CACNB4, CDO1, CHUK, CRH, CRKL, EPHB3, FGF3, GPX1, NRG1, HOXD9, IGF2, MGMT, OXTR, PAM, RAF1, RAG1, RAP1GAP, SOX10, SRF, TYR, WNT11, CCNB2, EIF2AK3, BCL2L11 |
1202 | GO:0044707 | 0.00 | 1.96 | 330.44 | 482 | 1616 | single-multicellular organism process | ABCA1, ABCA4, ACTB, ACTG2, ACTL6A, ACTN1, ADAM10, AEBP1, AGTR1, APLNR, NR0B1, AK2, ALAS2, ALDH1A3, ALDH3A2, ALK, AMBN, AMELY, AMPD2, ANG, APAF1, APLP2, APRT, AQP6, ARAF, ARG2, ARSE, ASS1, ASTN1, ATP5F1, ATR, BARD1, BCL2L1, TNFRSF17, BOK, ZFP36L2, BSG, KLF5, BTF3, BYSL, CAPN5, DAGLA, CAMK2A, CASP9, CCNE1, CCNF, CD3D, CD7, CD8A, CD9, TNFSF8, ENTPD2, CD59, CD72, CDH1, CDK2, CDK4, CDKN1A, CDO1, CEBPE, CENPE, CENPF, CHD2, CHN1, TBCB, AP2S1, CLC, CLN5, COL4A5, COL4A6, COL6A2, COL6A3, COL9A2, COL9A3, COL15A1, COX6B1, CR2, CRYBA4, CRYGB, CSNK2A1, CSNK2A2, CSRP1, CSRP2, CTF1, CYLC1, CYLC2, DAD1, DGKB, DAPK3, DAZ1, DDX1, DHFR, DIAPH2, DLG2, DLG3, DMBT1, DNASE1L2, DNM2, DNMT1, RCAN1, EPYC, DUSP1, DUSP5, E4F1, EBF1, TYMP, EDA, PHC2, EFNA3, EFNA4, EIF2B1, EIF4A1, ELAVL1, ELAVL3, EML1, EMP2, EPHA5, EPHA8, EYA4, ERCC3, ETV6, EVPL, EXTL1, EYA2, EZH1, F2RL2, F10, FABP7, FANCF, FANCG, GPC4, FGD1, FGF4, CENPI, FSHR, NR5A2, FZD2, GABRA4, GDF9, GFRA1, GJB1, GLUD1, GNA15, GNAI1, GNAT1, GNAT2, GNGT1, GNRH2, GNRHR, GP9, GPM6A, GPX1, GRB7, GRID2, HIST1H1T, HBD, HBE1, HCCS, HEXB, HIC1, HIVEP2, HLF, HMBS, NR4A1, HMX2, HNF4G, ONECUT1, HPGD, HPRT1, HSD11B1, HSF4, IDH1, IDUA, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGF1R, IL1RAP, IL1RN, IMPDH1, IMPDH2, ING2, INSIG1, INSRR, ITGA1, ITGA9, ITGAM, ITGAV, JARID2, KCNC2, KCNJ8, KIF5A, KRT2, KRT9, KRT13, KRT83, LAMA3, LAMA4, LAMP2, LCAT, LIM2, LTA4H, SMAD9, MAL, MARK3, MATN3, MGMT, ATXN3, DRG1, CNOT2, YBX1, NTN3, NUMA1, ODF1, OGDH, OLR1, OMP, OVOL1, OXCT1, P2RX5, PRDX1, PAM, PAX9, PCDH9, SERPINA5, PCNA, PCOLCE, PEPD, PEX13, PF4V1, PHF2, SERPINB5, PIM1, PIP4K2A, PPP2R5D, PPP5C, PRCP, PRKACG, PRKAR2A, PRKX, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTPN6, PTPRA, PTPRJ, PTPRN, PTPRS, PURA, QDPR, RAB1A, RAB5A, RAB27A, RAC3, RAD23B, RAD51C, RAD51B, RAF1, RALA, RAP2A, RAP2B, RASA2, RBM4, RCN1, PRPH2, RHAG, RPGR, RPL22, RPL24, RPS4Y1, RPS6KA1, RRM1, RYK, S100A1, S100A2, S100A4, S100A7, S100A8, S100A12, S100A13, SATB1, SCNN1A, SCNN1B, SCNN1G, SDC4, SDHA, TRAPPC2, SELE, SELL, SELPLG, SRSF1, SRSF5, SGCA, SGCB, SHB, SMTN, SLC12A1, SMARCA1, SMARCA2, SMARCA4, SMARCE1, SNRPE, SOS2, SPRR2A, SPRR2D, SPRR2E, SPRR2G, SPRR3, SREBF1, SRPK2, STRN, STXBP3, TACC1, TAZ, HNF1A, TNFRSF1A, TNFRSF1B, TOP2A, TOP2B, TPD52, TRPC4, TRPC5, TSG101, TSPY1, TUBA4A, TULP1, TYMS, TYR, TYRO3, TYROBP, UPK2, UPK3A, CLRN1, VAV1, WFS1, YWHAZ, ZNF3, ZNF7, ZNF22, ZNF24, ZNF45, ZNF74, ZNF141, ZNF148, ZBTB17, VEZF1, ZNF217, PRDM2, RNF103, SCG2, AIMP2, SLC7A5, MADCAM1, DPF1, SMC1A, PICALM, FZD4, FZD6, FZD8, GFI1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, SOX14, BCAR3, CUL3, CUL1, GAS7, COPS3, PIR, KLF7, UNC5C, AKR1C3, DYNLL1, PEA15, JRKL, DGAT1, EED, ADAM19, ADAM15, TNFRSF18, TNFRSF10D, TNFRSF10B, SCEL, TNFRSF10A, CDKL1, SAP30, HESX1, LIN7A, PROZ, ARHGEF7, VNN2, EIF2B3, EIF2B2, EIF2S2, BSN, HIST1H3F, RNF8, BAZ1B, DOK2, PAPSS1, CLDN1, ATP6V0D1, SMC3, CCNB2, SYNGR3, DYRK1B, EXO1, ZMYM6, AURKB, COPS2, TRIP11, GTF3C5, SLC9A3R1, PICK1, CHST3, ONECUT2, PSMF1, SLC4A7, ADAMTS4, ADAMTS3, ADAMTS2, LITAF, BAG3, NRG2, APBA3, CXCL14, SOX13, KLK4, GNA14, FEZ2, ZNF516, CROCC, ADAMTSL2, SNX17, SPOCK2, RB1CC1, SPATA2, ARHGEF11, GINS1, ZBTB24, GAB2, TRIL, NR1D2, RBX1, REC8, SLC12A6, NR2E3, RANBP9, ABCB6, COL4A3BP, ARPC5, ARPC1B, ACTR2, ARPC2, ARFRP1, RASA4, FARP1, WASF2, ZNF256, RNF41, PSME3, DHRS2, PSMD14, ABCC4, IRX5 |
1203 | GO:0040017 | 0.00 | 1.95 | 41.72 | 66 | 178 | positive regulation of locomotion | ANGPT1, ANXA3, BMP4, COL1A1, CSF1R, CTSH, DAPK3, DIAPH1, ETS1, F2R, F10, FBLN1, FGF7, FGR, FLT1, FLT4, FSHB, GPLD1, GRB7, HGF, ONECUT1, ICAM1, IFNG, IGF1, IGF1R, ILK, INS, ITGA4, ITGA5, ITGAV, ITGB1, JUN, KIT, KITLG, P2RY2, P2RY6, PRKCE, PTAFR, PTK2, RPS6KB1, SELE, SELP, SEMA3F, SNAI1, SOX9, SPARC, TRIM21, TRIP6, VIL1, VTN, WNT11, SEMA3B, MADCAM1, IKBKAP, NUMB, TNFRSF18, NRP2, ARHGEF7, ITGB1BP1, ONECUT2, BAG4, BCAR1, RAPGEF2, SEMA3E, HDAC6, PDCD6 |
1204 | GO:1903530 | 0.01 | 1.95 | 16.95 | 27 | 73 | regulation of secretion by cell | ANGPT1, BCR, CAMK2A, CHRNB4, CRP, DRD3, FBLN1, B4GALT1, IFNA2, IL13RA2, LLGL2, NTRK2, PAM, PFN2, RAB3B, RAC2, RALA, CX3CL1, SPINK1, STXBP2, STXBP3, SYN1, SYT4, TRAF2, ATG5, SNCAIP, RIMS2 |
1205 | GO:0006766 | 0.00 | 1.95 | 20.80 | 33 | 88 | vitamin metabolic process | ACACB, ACPP, CBR1, AKR1C4, CLPS, CTRB1, CYB5A, CYP3A4, DHFR, CYB5R3, GPC4, GIF, GPC3, HLCS, IFNG, PTGIS, ABCD4, RBP1, RBP2, RXRA, SDC4, SHMT1, SHMT2, SLC2A3, SNAI1, SLC25A16, FGF23, AKR1C3, VNN2, SLC5A6, RGN, GSTO1, SDC3 |
1206 | GO:0018209 | 0.00 | 1.95 | 30.96 | 49 | 131 | peptidyl-serine modification | ANGPT1, ARAF, ATR, BAX, CAMK2A, CCNB1, CD44, CDK2, CLK1, CSNK1D, CSNK1G3, DCN, GCG, HCLS1, HRC, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, ILK, SMAD7, NTRK2, NTRK3, PFN2, PRKAA1, PRKCE, PRKCI, PRKD1, PRKCQ, PRKX, RAF1, SGK1, SNCA, VRK1, BCAR3, OGT, RIPK1, RIPK2, RPS6KA4, LATS1, AURKB, EIF2AK3, BAG4, SPOCK2, SGK2, AKAP9 |
1207 | GO:0061572 | 0.00 | 1.95 | 18.91 | 30 | 80 | actin filament bundle organization | ABL2, ACTN1, ADD1, ARHGAP6, BBS4, CTGF, DPYSL3, S1PR1, LPAR1, PTK2B, LIMK1, SMAD3, MYO1B, PFN2, PRKCQ, RAC1, SDC4, SLC9A1, FSCN1, SRF, HSP90B1, TSC1, VIL1, WNT11, ARHGEF5, CUL3, GAS7, ITGB1BP1, BAG4, WASF2 |
1208 | GO:0006614 | 0.01 | 1.95 | 17.02 | 27 | 72 | SRP-dependent cotranslational protein targeting to membrane | FAU, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, SRP9, SRP14, RPL14, RPL23 |
1209 | GO:0007498 | 0.01 | 1.95 | 15.13 | 24 | 64 | mesoderm development | ACVR2B, BMP4, BMPR1A, BMPR2, BTK, EPHA2, EXT2, EYA2, ITGB1, SMAD1, SMAD3, OVOL1, PRKAR1A, RPL38, SNAI1, SRF, TAL1, TSPY1, KDM6A, WNT11, TP63, CHRD, KLF4, HAND1 |
1210 | GO:0030010 | 0.02 | 1.95 | 11.34 | 18 | 48 | establishment of cell polarity | KRIT1, CENPA, EPHB1, PTK2B, FLOT2, LLGL2, NUMA1, PRKCI, PTK2, CCL21, FSCN1, DYNLT1, ARHGEF2, ZW10, SLC9A3R1, ARHGEF11, RNF41, SPRY1 |
1211 | GO:0002260 | 0.03 | 1.95 | 9.45 | 15 | 40 | lymphocyte homeostasis | ABL1, BAX, TNFRSF17, TSC22D3, IL2RA, LMO1, P2RX7, RAG1, SOS2, STAT5B, IKBKG, TNFSF14, CCNB2, CHST3, BCL2L11 |
1212 | GO:0050891 | 0.03 | 1.95 | 9.45 | 15 | 40 | multicellular organismal water homeostasis | AVPR2, GNAS, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, SCNN1A, SCNN1B, SCNN1G, SRF, WFS1, TP63, CLDN1 |
1213 | GO:1902806 | 0.00 | 1.94 | 23.40 | 37 | 99 | regulation of cell cycle G1/S phase transition | ANXA1, CDK2, CDKN1A, PIM1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTPN6, RB1, RPA2, SMARCA4, ADAM17, TP73, UBB, UBE2E2, CUL4A, TP63, CRADD, PSMF1, PSME3, PSMD14, CTDSPL |
1214 | GO:0045087 | 0.00 | 1.94 | 81.24 | 127 | 350 | innate immune response | ABL1, ABL2, ACTB, ANG, ANGPT1, ANXA1, APP, ARAF, ART1, ASS1, AXL, BAD, BCL2L1, BLK, C3, C7, CAMK2A, CASP9, CD3G, CD4, CD6, CD28, CD44, CD58, CD59, CDKN1A, CLU, CR2, CSF1R, CSF2RB, DAPK3, DUSP5, EPRS, PTK2B, FAU, FCN2, FGA, FGF3, FGF4, FGF7, FGFR3, FGR, GAPDH, GRB2, GRIN2A, NRG1, NR4A1, ICAM1, IFNG, IFNGR1, IL1RAP, IL2RA, KIT, LIMK1, MARK3, KITLG, CIITA, FOXO4, P2RX7, PRDX1, PCBP2, CFP, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKD1, PRKCQ, PRKCSH, PTAFR, PTEN, PTK2, PTPRA, RAB27A, RAC1, RASA2, RPL39, RPS6KB2, S100A7, S100A8, S100A9, S100A12, CCL21, CCL22, CCL25, XCL1, CX3CL1, SFTPD, SHC1, SLPI, SNCA, SRPK2, TRIM21, STAT6, XCL2, TRAF2, TYROBP, UBA7, SUMO1, VIP, VTN, LAT2, XRCC5, TRIM25, FGF23, HIST2H2BE, CUL3, STX11, PEA15, ADAM15, TAX1BP1, KYNU, ARHGEF2, GRAP2, ATG5, NRG2, RAPGEF2, GAB2, RBX1, ARPC5, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, WASF2 |
1215 | GO:0019882 | 0.00 | 1.94 | 34.27 | 54 | 145 | antigen processing and presentation | ARF1, CANX, CD1B, CD8A, CD36, CENPE, AP1S1, AP2S1, CTSE, CTSH, CYBA, ACE, DYNC1H1, DNM2, FCGRT, ICAM1, IFNG, ITGAV, KIF5A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, RAB3B, RAB4A, RAB5B, RAB6A, RAB27A, CCL21, UBB, AP3B1, DYNLL1, CTSF, AP1M1, AP3D1, RAB33A, KIF3B, PSMF1, AP1M2, PSME3, PSMD14 |
1216 | GO:0040013 | 0.00 | 1.94 | 34.27 | 54 | 145 | negative regulation of locomotion | ACVRL1, AGTR2, ALOX15B, ANGPT2, APOH, ARHGAP4, ARHGDIB, BCR, BST2, KRIT1, CD63, CTNNA1, CX3CR1, DCN, DPEP1, DPYSL3, FBLN1, NRG1, HRG, IFNA2, IGFBP3, ILK, ITGAV, SMAD7, SERPINE1, SERPINF1, PFN2, PTEN, PTN, PTPRJ, PTPRR, RAP2A, RAP2B, CCL21, CCL25, SEMA3F, SP100, SRF, STAT3, STC1, NR2F2, WNT11, TRIM25, SEMA3B, CHRD, ADAM15, NRP1, RGN, ITGB1BP1, KLF4, SLIT2, SLC9A3R1, SEMA3E, RNF41 |
1217 | GO:0007179 | 0.01 | 1.94 | 15.80 | 25 | 67 | transforming growth factor beta receptor signaling pathway | ACVRL1, BMPR1A, CAV3, CBL, CCNC, CCNT2, CDK8, CREB1, FSHB, FUT8, GDF9, HPGD, ING2, JUN, LTBP2, SMAD1, SMAD9, SERPINE1, PTK2, SOX11, SP1, KLF10, USP9X, USP9Y, GDF15 |
1218 | GO:0044106 | 0.00 | 1.94 | 32.38 | 51 | 137 | cellular amine metabolic process | ABAT, ARG1, ARG2, ASL, ASS1, BCHE, BHMT, CHAT, CHKB, CHRNB2, CKM, COMT, CPS1, DBI, FGF7, GATM, GPLD1, HPRT1, IDO1, INS, LCAT, LIPC, OAZ1, OAZ2, PCYT1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, SMS, SNCA, TACR3, KYNU, PSMF1, NR1H4, SLC25A15, PSME3, PSMD14 |
1219 | GO:0072331 | 0.00 | 1.94 | 26.00 | 41 | 110 | signal transduction by p53 class mediator | ATR, ATRX, BAX, BCL3, BOK, BRCA2, CD44, CDK2, CDKN1A, DDX5, EP300, HIC1, IFI16, ING2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, SNAI1, SP100, TP73, UBB, DYRK2, TP63, CRADD, PSMF1, PSME3, PSMD14 |
1220 | GO:0050678 | 0.00 | 1.94 | 36.87 | 58 | 156 | regulation of epithelial cell proliferation | ACVRL1, ANG, APOH, ARG1, ARNT, BAD, BAX, BMP4, BMPR1A, BMPR2, BRCA2, KLF9, KRIT1, CDK6, CCR3, CYBA, DLX5, ECM1, EDNRA, EGR3, ETV4, F3, FGF7, FGFR3, FLT4, B4GALT1, GPC3, GPX1, HMGN1, NR4A1, IFNG, IGF1, IHH, JUN, KDR, SMAD3, SERPINF1, PGR, SERPINB5, PRKD1, PTEN, PTN, RAP1GAP, RB1, SCN5A, SOX9, SOX11, SPARC, NR2F2, VEGFB, VIP, SCG2, FZD7, TP63, NRP2, NRP1, RGN, PDCD6 |
1221 | GO:0006334 | 0.02 | 1.94 | 12.00 | 19 | 51 | nucleosome assembly | ATRX, CENPA, CENPI, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, HIST1H1A, SET, SOX9, TSPY1, HIST1H2BL, HIST1H2BN, HIST1H2BM, HIST1H2BO, HIST2H2BE, SMARCA5, RUVBL1 |
1222 | GO:0032270 | 0.00 | 1.94 | 142.46 | 219 | 613 | positive regulation of cellular protein metabolic process | ABL1, ABL2, ACVR2B, ACVRL1, ADRA1B, AGTR1, AGTR2, ALK, ANG, ANGPT1, BIRC3, XIAP, ARAF, ARNT, ATP6AP1, AVPR2, BCL3, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, CALM3, CAMK2A, CCNC, CCNT2, CD3E, CD4, CD28, CD36, CD44, CDK4, CDKN1A, CENPE, CIRBP, CRH, CRKL, CSF1R, CSF2RB, CSPG4, CTF1, DAZ1, ACE, DNMT1, DNMT3B, DUSP5, LPAR1, EDNRA, EFNA1, EFNA5, EIF5A, ELAVL1, EMP2, EPHA8, ERCC6, F2, FGA, FGF3, FGF4, FGF7, FGFR3, FLT1, FLT3, FLT3LG, FLT4, FPR1, FSHR, FYN, GCG, KAT2A, GDF9, GNG3, GOLGA2, GRB2, RAPGEF1, GRIN2A, GRM1, HIST1H1B, HCLS1, HGF, NRG1, UBE2K, HMGCR, HPX, HTR2C, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGF1, IGF1R, IGF2, IGFBP3, IL1A, IL2RA, IL12B, IL13, IL18, ILK, INHA, INS, IRAK1, IRAK2, ISL1, ITGA1, ITGA5, ITGB1, JARID2, JUN, KDR, KISS1, KIT, LTF, MARK3, KITLG, MAP3K11, PPP1R12A, NTRK2, NTRK3, P2RX7, PFN2, PIM1, PPP5C, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRKD1, PSAP, PTAFR, PTPRA, RAC1, RAF1, RAP2A, RAP2B, RASA2, RPS6KB1, RPS6KB2, RXRA, RYK, S100A7, S100A12, CCL21, CCL22, CCL25, XCL1, CX3CL1, SDC4, SHC1, STIL, SOX9, SREBF1, STK10, XCL2, ADAM17, TNFRSF1A, TP73, TPD52L1, TTK, UBE2L3, UBE3A, NR1H2, VEGFB, VTN, WFS1, WNT1, WNT11, FZD5, AIMP2, ARHGEF5, FGF23, CDK2AP1, FZD4, FZD7, FZD8, BCAR3, IKBKG, CDC14B, PDE5A, PEA15, EED, RIPK2, TNFRSF18, NRP1, RPS6KA4, TNFSF18, UNC119, LATS1, ARHGEF2, VAPB, ITGB1BP1, GPR55, KLF4, AKAP6, GDF15, BAG4, NRG2, TRAF4, RAPGEF2, SLK, EIF4A3, ATG13, RB1CC1, ZEB2, OXSR1, RBX1, RAD50, AKAP9, RASA4 |
1223 | GO:0009790 | 0.00 | 1.94 | 52.85 | 83 | 228 | embryo development | ACVR2B, ACVRL1, ADAM10, ADAR, ADD1, APLNR, ANGPT1, APAF1, BAX, BCL2L1, BMPR2, BRCA2, BTF3, BYSL, CCNB1, COL1A1, COL6A1, DAD1, DDX5, DMBT1, DUSP1, DUSP5, EDNRA, EMX1, EN1, EVX1, EXT2, EYA2, FGF4, FLT1, NR5A2, FUT8, GATA6, GPC3, GNAQ, NRG1, HOXC10, HOXD12, ISL1, ITGA5, ITGAV, ITGB1, CNOT2, YBX1, OPA1, P2RY2, PRKAR1A, PSMC3, PSMC4, PTK2, PTPRR, RALA, RCN1, RXRA, SDC4, SRSF1, SOX10, TOP1, TOP2A, TSC1, VTN, ZBTB17, FOSL1, USP9X, CUL4A, CUL3, COPS3, TP63, CHRD, DLK1, SCEL, EIF2S2, LATS1, CCNB2, SLIT2, PICK1, APBA3, IFT140, GINS1, BCL2L11, COL4A3BP, ARFRP1, ATP6AP2 |
1224 | GO:0002694 | 0.00 | 1.93 | 49.76 | 78 | 211 | regulation of leukocyte activation | ANXA1, AXL, BAD, BCR, PRDM1, BMP4, BPI, BTK, CBLB, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD28, CD86, CD37, CD59, CDKN1A, CHRNB2, CLC, CTLA4, DPP4, EFNB1, EGR3, FLOT2, FLT3, FLT3LG, FYN, GRB2, IFNA2, IFNG, IGF1, IGF2, IHH, IL2RA, IL10, IL12B, IL18, IDO1, INHA, IRF1, LMO1, PRKAR1A, PRKCQ, PTAFR, PTPN6, RAC1, RAG1, RARA, CCL21, XCL1, SFTPD, SNCA, SOS2, SOX11, STAT5B, STAT6, TRAF2, TNFSF4, TYRO3, SCGB1A1, UNG, VAV1, AP3B1, PDE5A, TNFSF14, TNFSF9, RIPK2, AP3D1, TNFSF18, IL1RL1, SOCS6, GRAP2, IL27RA, SOX13, RNF41 |
1225 | GO:0051250 | 0.01 | 1.93 | 15.83 | 25 | 67 | negative regulation of lymphocyte activation | ANXA1, AXL, PRDM1, BMP4, CBLB, CTLA4, FLT3, IFNA2, IHH, IL2RA, IL10, IDO1, INHA, IRF1, PRKAR1A, PTPN6, XCL1, SFTPD, SOX11, TNFSF4, TYRO3, SCGB1A1, PDE5A, TNFSF18, SOCS6 |
1226 | GO:0098727 | 0.01 | 1.93 | 15.83 | 25 | 67 | maintenance of cell number | ASCL2, BMPR1A, ZFP36L2, CDX2, DDX6, EIF4E, ELAVL1, FGF4, FGFR3, IGF1, RBPJ, KIT, CNOT2, PCM1, RAF1, SALL1, SOX9, STAT3, TAL1, KLF10, SMC1A, FZD7, CUL4A, SMC3, KLF4 |
1227 | GO:0098662 | 0.00 | 1.93 | 55.50 | 87 | 238 | inorganic cation transmembrane transport | ABL1, ANXA5, ATP2A1, ATP2B1, ATP2B2, ATP2B3, BAX, BMP4, CACNA1A, CACNA1B, CACNB4, CALM3, CASQ1, CASQ2, CNGA1, CYBA, DIAPH1, DPP6, EDNRA, F2, F2R, PTK2B, GPM6A, XCR1, GRIN2A, HRC, HTR2C, IL13, ITGAV, ITPR1, KCNA1, KCNA3, KCNA4, KCNC2, KCND2, KCND3, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN4, KCNQ1, KCNS2, KCNS3, NTSR1, P2RX1, P2RX7, PDE4B, PLN, PRKD1, PTPN6, REST, RYR1, RYR2, S100A1, CCL21, XCL1, SNCA, TRPC1, TRPC3, TRPC4, TRPC5, SUMO1, TRPV1, SLC30A2, KCNAB1, RGN, KCNAB3, KCNK6, GSTO1, AKAP7, AKAP6, ATG5, OXSR1, SLC12A6, ABCC9, AKAP9, KCNMB2 |
1228 | GO:0006338 | 0.03 | 1.93 | 10.12 | 16 | 43 | chromatin remodeling | RERE, ATRX, BRDT, CHEK1, KAT2A, HMGA1, RB1, SATB1, SMARCA2, SMARCD3, SOX9, TOP1, TTF1, TP63, BAZ1B, CHD1L |
1229 | GO:0000077 | 0.00 | 1.93 | 22.22 | 35 | 94 | DNA damage checkpoint | ATR, CDK2, CDKN1A, CHEK1, FOXO4, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, RPA2, TP73, UBB, CUL4A, CDC14B, TP63, PEA15, CRADD, PSMF1, CLOCK, FEM1B, PSME3, PSMD14 |
1230 | GO:0019233 | 0.03 | 1.93 | 10.13 | 16 | 43 | sensory perception of pain | CHRNB2, CNR1, DLG2, EDNRA, EPHB1, FYN, IAPP, IL12B, KCNA1, KCND2, P2RX4, P2RX7, P2RY2, PENK, PTGS1, TRPV1 |
1231 | GO:0009161 | 0.00 | 1.93 | 31.20 | 49 | 132 | ribonucleoside monophosphate metabolic process | ADSS, AK1, AK2, ALDOC, AMPD1, AMPD2, APRT, ARNT, ATP1A2, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1B2, ATP6V0A1, BAD, TSPO, COX8A, COX15, CTNS, DLG2, DLG3, ENO2, GAPDH, HPRT1, IGF1, IMPDH1, IMPDH2, INS, LDHC, OGDH, P2RX7, PFAS, PGAM1, PPP2R5D, PRKAA1, PRKAG1, SDHC, SNCA, STAT3, TAZ, UPP1, UQCRC1, UQCRC2, UQCRH, OGT, SLC25A13 |
1232 | GO:0071772 | 0.00 | 1.93 | 20.32 | 32 | 86 | response to BMP | ABL1, ACVR2B, ACVRL1, XIAP, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, RUNX2, DLX5, FBN1, GATA4, GATA6, GDF9, GPC3, RBPJ, ILK, KCND3, SMAD1, SMAD6, SMAD7, SMAD9, RYR2, SOX11, WNT1, USP9X, USP9Y, CHRD, PHOX2B, ZFYVE16 |
1233 | GO:0030334 | 0.03 | 1.93 | 10.10 | 16 | 44 | regulation of cell migration | ANXA1, ECM1, EFNA1, EPHA2, EMP2, EFEMP1, FGF4, LAMA3, LAMA4, PRCP, PRKX, SGK1, STK10, SOX14, UNC5C, SLK |
1234 | GO:0048754 | 0.00 | 1.92 | 18.43 | 29 | 78 | branching morphogenesis of an epithelial tube | AGTR2, BAX, BMP4, CAV3, CD44, CTSH, EDNRA, EPHA2, ETV4, ETV5, B4GALT1, GPC3, HHEX, FOXA2, IGF1, IHH, ILK, KDR, PGR, PSPN, SALL1, SLC12A2, SOX9, SRF, WNT1, NRP1, SLIT2, SEMA3E, SPRY1 |
1235 | GO:0043086 | 0.01 | 1.92 | 14.56 | 23 | 63 | negative regulation of catalytic activity | ACACB, ANXA3, ANXA5, CNR1, DRD3, DRD5, GALR1, HP, IL13, INS, PPP1R12A, OAZ1, OAZ2, PALM, PPP1R8, PTN, SET, SNCB, SCGB1A1, APBA3, GABBR2, PHACTR2, HDAC6 |
1236 | GO:0006606 | 0.03 | 1.92 | 10.78 | 17 | 46 | protein import into nucleus | ADAR, ARNTL, CSE1L, F2R, IFNG, JUN, NUP98, RAN, SIX3, STAT3, NUP214, AKR1C3, RPL23, ZFYVE9, NUP155, IPO13, NUP93 |
1237 | GO:0044237 | 0.00 | 1.92 | 29.48 | 47 | 153 | cellular metabolic process | ACO2, ACY1, ALB, ALPI, ALPPL2, ARL1, ARL2, BSG, CA4, COX7A1, CYB5A, CYC1, CYP8B1, DGKB, CYB5R3, GALK2, GNG10, FFAR1, FFAR3, IDH3A, ITPR1, KCNC2, KCNJ11, KCNS3, PEPD, PRCP, PRG2, SCO1, SDHA, SDHB, SDHD, SLC2A3, SLC6A6, SLC7A4, SLC10A1, SLC20A1, SLCO1A2, SLC22A2, SNAP25, SYT5, UGT2B7, SLC7A5, CES2, DGKI, MINPP1, FAM20B, DHRS2 |
1238 | GO:0006979 | 0.00 | 1.92 | 43.58 | 68 | 185 | response to oxidative stress | ABL1, ALAD, ALDH3A2, ANXA1, APP, ARG1, ARNT, ARNTL, BAD, BMP4, CAT, CD36, CDK2, CHUK, COL1A1, DHFR, DNM2, DPEP1, DUSP1, ERCC3, ERCC6, ETS1, ETV5, F3, PTK2B, FUT8, GJA3, GPX2, HBA2, IDH1, IL1R1, JUN, KCNC2, KPNA4, MGMT, OLR1, PRDX1, PENK, PPP2CB, PPP5C, PRKAA1, PRKD1, PTGS1, PTPRN, RPS3, S100A7, SFPQ, SHC1, SNCA, STAT6, STAU1, TAT, TRAF2, TRPM2, SCGB1A1, XPA, FOSL1, ATRN, AKR1C3, RGN, PDLIM1, KLF4, OXSR1, HDAC6, IL18BP, SGK2, DHRS2, RCAN2 |
1239 | GO:0060429 | 0.04 | 1.91 | 8.86 | 14 | 39 | epithelium development | ARG2, BRCA2, CAT, EN1, GJA4, SMAD1, SMAD6, SMAD7, SMAD9, STAT6, CHRD, ADAMTSL2, IFT140, ATP6AP2 |
1240 | GO:0006901 | 0.02 | 1.91 | 12.76 | 20 | 54 | vesicle coating | ARCN1, ARF1, CD59, AP2S1, COPA, CSNK1D, EPS15, GOLGA2, GRIA1, HIP1, PPP6C, RAB1A, TRAPPC2, PICALM, CUL3, USO1, COPB2, SEC22B, GOSR2, SNAP91 |
1241 | GO:0002253 | 0.00 | 1.91 | 67.83 | 105 | 287 | activation of immune response | ABL1, ACTB, BIRC3, XIAP, BAX, BLK, BTK, C3, C7, CACNB4, CALM3, CBLB, CD3D, CD3E, CD3G, CD4, CD28, CD86, CD36, CD59, CHUK, CLU, CR2, CREB1, CTLA4, CTSK, CYBA, DMBT1, ELK1, EP300, FCN2, FGR, FYB, FYN, GPLD1, GRB2, CFHR1, ICAM2, IFI16, IRAK1, IRAK2, IRF1, ITGAM, ITPR1, JUN, KCNN4, LIMK1, LTF, PDE4B, CFP, PPP2R5D, PRKACB, PRKACG, PRKCE, PRKCQ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, PTPN6, PTPRJ, RAC1, RAF1, RPS6KA1, SEC14L1, SKP1, HSP90B1, TYRO3, UBB, UBE2D2, VAV1, VTN, LAT2, CUL1, IKBKG, RIPK1, RIPK2, UBA3, GRAP2, PSMF1, BCAR1, TRIL, NR1H4, ARPC5, ARPC1B, ACTR2, ARPC2, WASF2, PSME3, PSMD14 |
1242 | GO:0097659 | 0.00 | 1.91 | 19.04 | 30 | 85 | nucleic acid-templated transcription | ANG, COX6A1, COX6B1, COX7C, COX8A, CSTF3, CTGF, GPX2, GTF3C1, GTF3C2, DRG1, PRDX1, PPP5C, PRKAG1, PTMA, RGS12, RHEB, SRSF1, SRSF5, SRSF7, SNRPE, SNRPF, TSC1, YWHAZ, SRSF9, DDX21, GTF3C5, GTF3C4, GTF3C3, RBM8A |
1243 | GO:0006936 | 0.01 | 1.90 | 14.67 | 23 | 63 | muscle contraction | ACTG2, ANXA1, ARG2, ATP1A3, CHUK, DTNA, GAA, GLRA1, ITGA1, KCNH2, RPS6KB1, RYR1, SCN4B, SCN7A, SRSF1, SGCA, SNTB1, TAZ, VEGFB, DYSF, NUP155, ARHGEF11, COL4A3BP |
1244 | GO:0045839 | 0.03 | 1.90 | 10.87 | 17 | 46 | negative regulation of mitotic nuclear division | ATRX, BMP4, BUB1B, CCNB1, CDC20, CDC27, CENPF, CHEK1, CSNK2A1, CSNK2A2, DUSP1, FGFR3, TTK, ZNF207, CDC23, CDC16, ZW10 |
1245 | GO:1901607 | 0.03 | 1.90 | 10.87 | 17 | 46 | alpha-amino acid biosynthetic process | AHCY, ASL, ASS1, BHMT, CPS1, CTH, DHFR, GATM, GLUD1, GOT2, OAT, PAH, PSPH, PYCR1, SHMT1, SHMT2, ALDH4A1 |
1246 | GO:0009259 | 0.00 | 1.90 | 61.45 | 95 | 260 | ribonucleotide metabolic process | ABCA1, ACACB, ADSS, AK1, AK2, ALDOC, AMPD1, AMPD2, APRT, ARNT, ATP1A2, ATP2B2, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1B2, ATP6V0A1, AVPR2, BAD, TSPO, CACNB4, CALM3, COX8A, COX15, CRH, CTNS, DLG2, DLG3, DRD3, DRD5, LPAR1, EDNRA, ENO2, PTK2B, FSHR, FZD2, GALR1, GAPDH, GCG, GHRHR, GNAS, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GUCY2D, HMGCR, HPRT1, HTR2C, IGF1, IMPDH1, IMPDH2, INS, LDHC, NTRK2, OGDH, P2RX7, P2RY11, PALM, PDE4B, PDE8A, PFAS, PGAM1, PPP2R5D, PRKAA1, PRKAG1, RAF1, RCVRN, SDHC, SNCA, STAT3, SULT1E1, SULT1A3, SULT1C2, SULT2B1, TAZ, UPP1, UQCRC1, UQCRC2, UQCRH, VIP, VIPR2, WFS1, OGT, PDE5A, PAPSS1, AKAP6, GABBR2, AKAP12, GUCA1C, SLC25A13 |
1247 | GO:0080134 | 0.02 | 1.89 | 11.45 | 18 | 51 | regulation of response to stress | ABAT, APOH, F2, F2R, F3, F7, FAP, FGA, GP1BA, FOXA2, HRG, KNG1, PRKCQ, SELP, TRPC3, USF1, VEGFB, VIL1 |
1248 | GO:0006757 | 0.05 | 1.89 | 8.98 | 14 | 38 | ATP generation from ADP | ALDOC, ARNT, ENO2, GAPDH, IGF1, INS, OGDH, P2RX7, PGAM1, PPP2R5D, PRKAA1, PRKAG1, STAT3, OGT |
1249 | GO:0032729 | 0.05 | 1.89 | 8.98 | 14 | 38 | positive regulation of interferon-gamma production | ABL1, ABL2, BCL3, CD3E, IL12B, IL12RB2, IL18, ISL1, PDE4B, TNFSF4, FZD5, TNFSF9, RIPK2, IL27RA |
1250 | GO:0072583 | 0.05 | 1.89 | 8.98 | 14 | 38 | clathrin-mediated endocytosis | AMPH, CANX, AP2S1, DNM1, HIP1, ITGA4, SNCA, SYT1, SYT5, PICALM, SYNJ1, UNC119, DNAJC6, SNAP91 |
1251 | GO:0040008 | 0.00 | 1.89 | 26.36 | 41 | 113 | regulation of growth | ACACB, ACTL6A, ALOX15B, APP, BBS4, BMP4, C3, CCNB1, CREB1, CXADR, DRD3, E4F1, FGFR3, GATA4, GATA6, GHRHR, GHSR, GPC3, GNAS, IGF2, RBPJ, IHH, ING2, KCNK2, PPIB, PTEN, PTK2, RAG2, RPS6KB1, SHC1, STAT3, STAT5B, TP73, VIL1, WFS1, ATRN, RUVBL1, SOCS3, LATS1, SOCS6, BCL2L11 |
1252 | GO:0048699 | 0.00 | 1.89 | 186.70 | 280 | 796 | generation of neurons | ABL1, ABL2, ACTB, ADAM10, ALK, ANGPT1, APP, ARAF, ARF1, ARHGAP4, PHOX2A, ARNTL, ASCL2, RERE, ATP2B2, PRDM1, BMP4, BMPR1A, BMPR2, BYSL, TSPO, CACNA1A, CACNB4, CALM3, CAMK2A, RUNX2, CD72, CDC20, CDH1, CDK6, CHN1, CHRNB2, AP2S1, CLU, CLN5, CNP, CNR1, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CRX, CSF1R, CSF2RB, CSNK2A1, CSNK2A2, CTF1, CTNND2, DAPK3, BRINP1, DDX6, DHFR, DLG3, DLX5, DNM1, DNM2, DNMT1, DNMT3B, DPYSL3, DRD3, EPYC, DUSP5, S1PR1, LPAR1, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EPHA2, EIF4E, EMX1, CTTN, EMX2, EN1, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, ERCC3, ETV4, ETV5, EVX1, F2, PTK2B, EFEMP1, FGF3, FGF4, FGF7, FGFR3, FZD2, GABRA5, GDI1, GFAP, GFRA1, GNAQ, GNAT1, GNAT2, GNGT1, GOLGA4, GRB2, RAPGEF1, GRID2, GRIN2A, HGF, FOXA2, HOXC10, HOXD9, HOXD10, HPRT1, IFNG, RBPJ, IHH, IL2RA, ILK, ISL1, ITGA1, ITGA5, ITGA9, ITGAV, ITGB1, JUN, KIF5A, KIT, LIMK1, CAPRIN1, MARK3, KITLG, NTF4, NTN3, OGDH, OPA1, OTX2, P2RY2, PALM, PAX3, PCP4, SERPINF1, PPP5C, PRKCI, PRKD1, PRKCQ, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTN, PTPRA, PTPRR, RAC1, RAC2, RAC3, RAF1, RAP1GAP, RAP2A, RARA, RARB, RASA2, RB1, REST, RHEB, RNF6, RPGR, RPL24, RPS6KA1, RXRA, RYK, SALL1, SCN5A, SDC4, SEMA3F, SGK1, SHC1, SMARCA1, SNAP25, SOS2, SOX3, SOX9, SOX11, STRN, SYT1, SYT4, TAL1, TBCE, DYNLT1, TNR, TP73, TRPC1, TRPC3, TRPC4, TRPC5, TTC3, TULP1, TULP3, TYROBP, UBB, CLRN1, VIM, WNT1, WNT11, XRCC2, XRCC5, RNF112, FZD5, SEMA3B, FGF23, RND2, PICALM, FZD4, FZD7, FZD8, CUL3, CNTNAP1, GAS7, KLF7, UNC5C, PEA15, NRP2, ARHGEF7, RPS6KA4, ARHGEF1, CBFA2T2, ARHGEF2, KLF4, COPS2, SLIT2, SLC9A3R1, NRXN3, NRXN1, PICK1, CHST3, ONECUT2, PSMF1, SLC4A7, BAG5, NRG2, AATK, FEZ2, RIMS2, SEMA3E, IFT140, CUL7, ARHGEF11, RNF10, RBX1, NR2E3, RANBP9, ARPC5, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, FARP1, PSME3, PSMD14, OLIG2, IRX5 |
1253 | GO:0046718 | 0.01 | 1.89 | 16.07 | 25 | 68 | viral entry into host cell | AXL, CD4, CD86, SCARB2, CR2, CXADR, DPP4, EPS15, GYPA, ICAM1, IFNA2, ITGA5, ITGAV, ITGB1, KPNA3, PVR, SELPLG, SLC10A1, TRIM21, DYNLT1, TYRO3, UVRAG, TRIM25, VAMP8, CLDN1 |
1254 | GO:0048878 | 0.01 | 1.89 | 17.25 | 27 | 76 | chemical homeostasis | CNR1, CRY2, CTSH, CYP11B1, DBH, FGF7, GCGR, GNAS, FFAR1, IDUA, PCK1, PRCP, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, RPS6, SFTPD, SLC2A4, SLC12A1, SOD2, STAT3, HNF1A, TP63, CLDN1 |
1255 | GO:0001764 | 0.01 | 1.89 | 18.67 | 29 | 79 | neuron migration | ASCL1, ASTN1, AXL, BAX, BBS4, DCC, FYN, GPM6A, NRG1, NRCAM, NTRK2, NTRK3, PCM1, PEX7, PEX13, PTK2, SPOCK1, SRF, STAT3, CNTN2, NR2F1, NR2F2, TOP2B, USP9X, SOX14, NRP1, PHOX2B, RAPGEF2, KIAA0319 |
1256 | GO:0007519 | 0.01 | 1.89 | 18.67 | 29 | 79 | skeletal muscle tissue development | ARNTL, KLF5, CASQ1, CSF1R, DCN, DDX5, TSC22D3, EGR2, EP300, GPX1, HLF, HMGCR, HOXD9, HOXD10, MEOX2, PRKAA1, RB1, RPS6KB1, RYR1, SOX11, TAZ, NR2F2, KCNAB1, SAP30, PHOX2B, USP2, COPS2, GTF3C5, NR1D2 |
1257 | GO:2001233 | 0.00 | 1.89 | 25.12 | 39 | 107 | regulation of apoptotic signaling pathway | CD44, CTH, CX3CR1, DBH, CTTN, FGA, FYN, GCG, GPX1, GRINA, HGF, NRG1, HSPB1, ICAM1, IGF1, IL1A, ING2, INS, ITGAV, OPA1, SERPINE1, RAF1, RPS6KB1, CX3CL1, SNAI1, SOD2, SP100, TPT1, TRAF1, VDAC2, WFS1, SCG2, NRP1, ARHGEF2, BAG5, RB1CC1, FEM1B, TRAP1, PSME3 |
1258 | GO:0043549 | 0.00 | 1.88 | 113.05 | 172 | 480 | regulation of kinase activity | ABL1, ACVR2B, ADAR, ALK, ANG, ANGPT1, APLP2, APP, ARAF, BAD, BAX, BMP4, CALM3, CAMK2A, CAV3, CCNC, CCNE1, CCNT2, CD4, CDC25A, CDC25C, CDK4, CDKN1A, CENPE, CHAD, CKS1B, CLU, CRKL, CSF1R, CSF2RB, CSPG4, DCN, ACE, DUSP1, DUSP5, LPAR1, EFNA1, EFNA5, EMP2, ERCC6, F2R, FGF3, FGF4, FGF7, FPR1, FYN, GCG, GNAQ, GNG3, GP1BA, GRB2, RAPGEF1, GRIN2A, GRM1, HGF, NRG1, HHEX, HMGCR, FOXA2, HSPB1, IGF1R, IGF2, IL2RA, IL12B, ILK, INS, IRAK1, IRAK2, ITGA1, LTF, MARK3, KITLG, MAP3K11, NTRK3, P2RX7, PCP4, PIM1, PPP2R1A, PPP5C, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRPSAP1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTPN6, PTPRA, PTPRJ, RAC2, RAF1, RANBP2, RAP2B, RASA2, RPS3, S100A12, SDC4, SHC1, STIL, SNCA, STK10, ADAM17, TAF7, NR2F2, TP73, TPD52L1, TRAF2, TSC1, TSG101, UBB, UVRAG, WNT11, ZNF16, FZD5, ARHGEF5, FGF23, FZD4, FZD8, CUL3, IKBKG, IKBKAP, PDE5A, PEA15, RIPK1, RIPK2, TNFRSF10B, TNFRSF10A, SOCS3, DIRAS3, UNC119, RGN, LATS1, VAPB, ITGB1BP1, SOCS6, SLC9A3R1, PSMF1, NRG2, TRAF4, RAPGEF2, SLK, ATG13, ZEB2, OXSR1, TNFSF15, RBX1, RAD50, AKAP9, RASA4, PSME3, PSMD14, SPRY1 |
1259 | GO:0032940 | 0.00 | 1.88 | 41.34 | 64 | 179 | secretion by cell | ABCA1, ACTN1, ACVR2B, AGTR1, ALB, ANXA3, APP, AXL, CACNA1B, CALM3, CANX, CD9, CD36, CD63, CHAT, CLU, CTGF, FGF7, GAD1, GCGR, HGF, HRG, IGF2, RBPJ, IL1RN, KIT, KNG1, LAMP2, LTBP2, P2RX1, SERPINE1, PCSK5, PSAP, PTPRN, PTPRN2, RAB1A, RAF1, S100A12, S100A13, SELP, SLC1A6, SLC6A13, SLC22A2, SPARC, HNF1A, TUBA4A, TYRO3, VEGFB, VIP, TRPV1, LAT2, SCG2, SYN3, FZD4, STX11, LIN7A, SYNJ1, DGKI, SNAP29, NRXN3, NRXN2, EIF2AK3, SCRN1, ABCC4 |
1260 | GO:0051604 | 0.00 | 1.88 | 46.08 | 71 | 195 | protein maturation | ADAM10, AEBP1, APAF1, BIRC3, XIAP, BIRC5, APOH, BAD, BAX, BGLAP, BOK, C3, C7, CASP9, CD59, CLN5, COL4A3, CTSE, CTSH, ACE, F2, F2R, F3, F7, F10, FGA, FSHB, GAS1, GZMH, HIP1, IFI16, IHH, KLKB1, SMAD3, P2RX1, P2RX7, SERPINE1, PCSK5, CFP, PRKACB, PROC, S100A8, S100A9, SNCA, CNTN2, CLEC3B, TRAF2, TSG101, UBB, UQCRC1, UQCRC2, VTN, WFS1, TRADD, RIPK1, CRADD, TNFSF10, TNFRSF10B, TNFRSF10A, PROZ, PCSK7, EIF2AK3, ADAMTS3, ADAMTS2, TMEM59, TNFSF15, CASP8AP2, PDCD6, BCL2L11, ATP6AP2, ZMPSTE24 |
1261 | GO:0043524 | 0.01 | 1.88 | 16.78 | 26 | 71 | negative regulation of neuron apoptotic process | ANGPT1, AXL, BAX, BCL2L1, CACNA1A, F2R, PTK2B, FYN, GABRA5, ILK, ISL1, JUN, NTF4, NTRK2, PCP4, PRKCI, SET, SNCB, SNCA, SOD2, TP73, TYRO3, VEGFB, WFS1, XRCC2, NRP1 |
1262 | GO:0031032 | 0.01 | 1.88 | 19.38 | 30 | 82 | actomyosin structure organization | ARHGAP6, BBS4, CASQ1, CASQ2, CAV3, CNN1, CNN2, CNN3, CTGF, S1PR1, LPAR1, PTK2B, ITGB1, LIMK1, SMAD3, PFN2, PRKAR1A, PRKCQ, RAC1, SDC4, SLC9A1, SRF, TSC1, WNT11, ARHGEF5, CUL3, ITGB1BP1, BAG4, CDC42BPB, WASF2 |
1263 | GO:0008285 | 0.00 | 1.87 | 74.54 | 114 | 317 | negative regulation of cell proliferation | ACVRL1, AGTR2, ALOX15B, APOH, BAX, BCHE, PRDM1, BMP4, BMPR2, BRCA2, KLF9, CBLB, KRIT1, CD9, TNFRSF8, CD37, CDK6, CDKN1A, COL4A3, CSF1R, CTLA4, CTNNA1, DLG3, ETS1, ETV3, ETV4, F2R, FABP7, PTK2B, FAP, FBLN1, FGFR3, FLT3, B4GALT1, GPC3, GPLD1, RAPGEF1, HMGA1, HRG, IFIT3, IGF1, IGFBP6, RBPJ, IHH, IL1A, IL2RA, IL10, IDO1, ING2, INPPL1, IRF1, ITGA1, ITGB1, JARID2, JUN, KISS1, SMAD1, SMAD3, SMAD6, FOXO4, OVOL1, SERPINF1, PRKAR1A, PTEN, PTPN6, PTPRJ, RAF1, RAP1GAP, RARA, RARB, RB1, REST, RXRA, S100A11, XCL1, SFRP5, SFTPD, SMARCA2, SOD2, SOX9, SPARC, SRF, STAT3, STRN, NR2F2, KLF10, TSC1, TSG101, SCGB1A1, WNT11, FZD5, SCG2, AIMP2, FOSL1, BAP1, CUL4A, CUL2, CUL1, KLF11, PPM1D, PDE5A, PHOX2B, RGN, IL1RL1, ITGB1BP1, SLIT2, SLC9A3R1, RAPGEF2, DLEC1, FGFBP1, NR2E3, RNF41, DHRS2, SPRY1 |
1264 | GO:0031330 | 0.00 | 1.87 | 25.29 | 39 | 107 | negative regulation of cellular catabolic process | ACACB, ADRA1B, BCL2L1, BUB1B, TSPO, CCNB1, CDC20, CDC27, CENPF, CNR1, CSNK2A1, CSNK2A2, DFFA, DUSP1, GATA4, GOLGA2, GPLD1, HGF, HP, IL10, INS, KIF25, SNCA, SNRNP70, STAT3, TSC1, TTK, WNT1, ZNF207, CDC23, CDC16, USP14, RGN, ZW10, PSMF1, BAG5, FEZ2, KDM4A, DHX34 |
1265 | GO:0046661 | 0.01 | 1.87 | 20.09 | 31 | 85 | male sex differentiation | NR0B1, ATRX, BAX, BCL2L1, BMPR1A, BOK, COL9A3, CTNNA1, FSHB, FSHR, GATA4, GATA6, ICAM1, ING2, INHA, KIT, KITLG, PRKACG, RARA, RRM1, SOX9, SRD5A1, SRY, STAT5B, UBB, AKR1C3, ADAM15, EIF2S2, REC8, BCL2L11, AKAP9 |
1266 | GO:0035113 | 0.01 | 1.87 | 14.89 | 23 | 63 | embryonic appendage morphogenesis | ALX3, BAX, BMP4, BMPR1A, RUNX2, DLX5, EN1, FGF4, GPC3, GNAQ, GNAS, HOXC10, HOXC11, HOXD9, HOXD10, HOXD12, IHH, RARB, SALL1, TULP3, FZD6, TP63, BCL2L11 |
1267 | GO:0050790 | 0.01 | 1.86 | 16.02 | 25 | 73 | regulation of catalytic activity | KRIT1, CCNE1, CDC25A, CDC25C, CDK2, CDK4, CKS1B, RCAN1, FXYD3, RAC2, RAP2B, RBL2, SGK1, TSG101, UVRAG, SHOC2, PIK3R3, IKBKAP, DYNLL1, DPM2, DIRAS3, SLC9A3R1, BAG3, FEM1B, RCAN2 |
1268 | GO:0006139 | 0.00 | 1.86 | 23.79 | 37 | 109 | nucleobase-containing compound metabolic process | ACPP, ALDOC, ATP1A2, ATP2B2, ATP6V1B2, BAD, CACNB4, COX15, CPS1, CTNS, DLG2, DLG3, ENO2, FUT8, GAPDH, HMGCR, IDH1, KCNQ1, MDH2, OGDH, PPP2R5D, PTGDR, RPE, SDHC, SULT1E1, SULT1A3, SULT1C2, SULT2B1, TAZ, TPMT, UQCRC1, UQCRC2, UQCRH, PDHX, DIRAS3, TP53I3, GNE |
1269 | GO:1903364 | 0.00 | 1.86 | 28.60 | 44 | 121 | positive regulation of cellular protein catabolic process | CAV3, CCNB1, CDC20, CDC27, CLU, CSNK1D, PTK2B, DNAJB2, SMAD7, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, RB1, SKP1, SUMO3, UBB, SUMO1, CUL3, CUL1, CDC23, CDC16, RGN, PSMF1, RNF14, DLGAP5, RNF40, PSME3, PSMD14 |
1270 | GO:0001501 | 0.00 | 1.86 | 25.97 | 40 | 111 | skeletal system development | ACVRL1, AEBP1, ARSE, BMP3, BMP8B, BMPR1A, CD44, COL9A2, VCAN, EPHA2, EN1, EXTL1, FBN1, EFEMP1, GNAQ, GPLD1, HEXB, HOXC10, HOXD12, IGF2, IHH, INHA, MATN3, PRDX1, PCSK5, RPL38, TRAPPC2, SNAI1, SP1, KLF10, CLEC3B, TYMS, WNT11, TP63, CHRD, DLK1, PAPSS1, HAND1, EIF2AK3, ADAMTS4 |
1271 | GO:0008584 | 0.01 | 1.86 | 15.58 | 24 | 66 | male gonad development | NR0B1, BAX, BCL2L1, BOK, COL9A3, CTNNA1, FSHB, FSHR, GATA6, ICAM1, INHA, KIT, KITLG, PRKACG, RARA, RRM1, SOX9, SRD5A1, SRY, AKR1C3, ADAM15, EIF2S2, BCL2L11, AKAP9 |
1272 | GO:0048856 | 0.03 | 1.86 | 11.37 | 18 | 58 | anatomical structure development | ALDOC, CBR1, CD63, CNN3, ITGAM, KRTAP5-9, KRT5, KRT6B, KRT32, KRT34, KRT83, RAB27A, RBP2, SUMO1, UPK1B, UPK2, TAGLN2, DHRS9 |
1273 | GO:0010951 | 0.00 | 1.86 | 35.21 | 54 | 149 | negative regulation of endopeptidase activity | BIRC3, XIAP, BIRC5, APLP2, APP, BST2, C3, CD44, COL4A3, COL6A3, CSNK2A1, CST6, DPEP1, SERPINB1, GPX1, HGF, HRG, IFI16, ITIH1, ITIH4, KNG1, SERPINE1, SERPINA5, SERPINF1, SERPINA4, SERPINB5, SERPINB9, SERPINB13, SERPINI2, PZP, RAF1, RAG1, RENBP, RPS6KA1, SERPINB4, SLPI, SNCA, SPINK1, SPOCK1, SERPINA7, TRAF2, VIL1, VTN, PICALM, SERPINB7, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, USP14, KLF4, PSMF1 |
1274 | GO:0045446 | 0.04 | 1.86 | 10.39 | 16 | 44 | endothelial cell differentiation | BMP4, S1PR1, GPX1, RAPGEF1, NRG1, ICAM1, RBPJ, KDR, PROC, PTN, PTPRS, STC1, TNFRSF1A, VEZF1, NRP1, RAPGEF2 |
1275 | GO:0048640 | 0.02 | 1.85 | 13.00 | 20 | 55 | negative regulation of developmental growth | ARHGAP4, BMP4, CAV3, CXADR, DCC, FGFR3, GNAS, KCNK2, PTEN, PTK2, RNF6, SEMA3F, TNR, TP73, SEMA3B, NRP1, CTDP1, SLIT2, AATK, SEMA3E |
1276 | GO:0001824 | 0.04 | 1.85 | 10.40 | 16 | 44 | blastocyst development | BRCA2, BYSL, CDX2, DAD1, DMBT1, IGF1, CNOT2, PSMC3, PSMC4, RAD51B, SP1, SRF, CUL3, LATS1, HAND1, GINS1 |
1277 | GO:0002062 | 0.04 | 1.85 | 10.40 | 16 | 44 | chondrocyte differentiation | ACVRL1, BMP4, BMPR1A, BMPR2, RUNX2, COL9A1, COL11A1, CTGF, EFEMP1, FGFR3, GPLD1, IHH, SMAD3, RARB, SOX9, EIF2AK3 |
1278 | GO:0043467 | 0.04 | 1.85 | 10.40 | 16 | 44 | regulation of generation of precursor metabolites and energy | ADRA1B, ARNT, GCGR, IGF1, IGF2, INS, P2RX7, PGAM1, PRKAA1, PRKAG1, SNCA, STAT3, DYRK2, OGT, EPM2AIP1, TRAP1 |
1279 | GO:0060563 | 0.04 | 1.85 | 10.40 | 16 | 44 | neuroepithelial cell differentiation | ASCL1, ATP2B2, EMX1, GNAQ, RBPJ, KIT, KITLG, RAB27A, RAC1, SOX10, SOX11, CLRN1, WNT11, SLC9A3R1, SLC4A7, ZEB2 |
1280 | GO:0007517 | 0.00 | 1.85 | 28.69 | 44 | 122 | muscle organ development | AEBP1, ASS1, KLF5, CASQ1, CHD2, COL6A3, COL11A1, CSF1R, CTF1, DCN, S1PR1, EGR2, EGR3, EP300, FZD2, GPX1, HLF, HOXD9, HOXD10, IGF1, ISL1, SMAD7, MEOX2, FOXO4, PAX3, RB1, RXRA, RYR1, RYR2, SCN8A, SGCA, SGCB, SMTN, SOX11, TAZ, NR2F2, TNNC1, TNNI3, KCNAB1, SAP30, PHOX2B, COPS2, GTF3C5, HAND1 |
1281 | GO:1901342 | 0.01 | 1.85 | 19.52 | 30 | 83 | regulation of vasculature development | ACVRL1, ANXA3, C3, CCR3, CTH, CTSH, ECM1, EFNA1, EPHA2, EMP2, ETS1, F3, PTK2B, FLT1, GATA4, GATA6, HGF, HSPB1, IL1A, ISL1, ITGA5, KDR, PRKD1, PTGIS, CX3CL1, SP100, VEGFB, SERPINB7, RAPGEF2, PDCD6 |
1282 | GO:0016337 | 0.02 | 1.85 | 14.25 | 22 | 62 | single organismal cell-cell adhesion | ACTB, CDH7, CDH9, CDH10, CSRP1, CTNNA1, CTNND2, GNAS, RAPGEF1, HSPB1, ICAM2, ICAM4, ILK, RAP2B, SHC1, SOX9, STXBP3, ICAM5, TYRO3, ZAN, SLIT2, GPA33 |
1283 | GO:0001655 | 0.00 | 1.85 | 35.29 | 54 | 150 | urogenital system development | ACVR2B, AGTR1, AGTR2, ANGPT1, ANGPT2, ARG2, ASS1, BAX, CAT, CENPF, COL4A3, CTSH, DCN, ACE, EDNRA, EMX2, EPHB2, EPHB3, FBN1, GPC3, HMGCS2, HOXC11, ILK, KCNJ1, KCNJ8, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, OVOL1, PCSK5, PRKX, PSPN, RARB, SALL1, SDC4, SLC12A1, SLC34A1, SOX11, SRD5A1, TP73, TSC1, UPK3A, WFS1, WNT1, WNT11, SERPINB7, NRP1, RGN, SLIT2, IFT140, BCL2L11, SPRY1 |
1284 | GO:0030111 | 0.00 | 1.85 | 39.94 | 61 | 169 | regulation of Wnt signaling pathway | ABL1, ABL2, XIAP, ARNTL, COL1A1, CSNK1D, CSNK2A1, CTNND2, DAPK3, DLX5, EDA, FGFR3, FZD2, RAPGEF1, HHEX, HIC1, IGFBP6, RBPJ, ILK, ISL1, SMAD3, PPP2R1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, SALL1, SFRP5, SIX3, SMARCA4, SOX9, SOX10, UBB, WNT1, WNT11, FZD5, FZD6, CUL3, RGS20, LATS1, PSMF1, ZEB2, RBX1, FRAT1, G3BP1, ATP6AP2, PSME3, PSMD14 |
1285 | GO:0009628 | 0.00 | 1.85 | 22.00 | 34 | 99 | response to abiotic stimulus | ATP2B1, CAMK2A, CASQ1, CD9, CDH8, CDK2, EIF2B1, HMGCS2, HSPA6, HSPB2, IL1A, IMPDH1, KCNJ3, ATXN3, NUP98, RANBP2, RPA2, RPA3, S100A13, DNAJC7, NUP214, AAAS, SLC14A2, SNN, EIF2B3, EIF2B2, EIF2AK3, BAG5, BAG4, NUP155, ZNF516, NUP93, HDAC6, PDCD6 |
1286 | GO:0044409 | 0.01 | 1.85 | 16.31 | 25 | 69 | entry into host | AXL, CD4, CD86, SCARB2, CR2, CXADR, DPP4, EPS15, GYPA, ICAM1, IFNA2, ITGA5, ITGAV, ITGB1, KPNA3, PVR, SELPLG, SLC10A1, TRIM21, DYNLT1, TYRO3, UVRAG, TRIM25, VAMP8, CLDN1 |
1287 | GO:0051806 | 0.01 | 1.85 | 16.31 | 25 | 69 | entry into cell of other organism involved in symbiotic interaction | AXL, CD4, CD86, SCARB2, CR2, CXADR, DPP4, EPS15, GYPA, ICAM1, IFNA2, ITGA5, ITGAV, ITGB1, KPNA3, PVR, SELPLG, SLC10A1, TRIM21, DYNLT1, TYRO3, UVRAG, TRIM25, VAMP8, CLDN1 |
1288 | GO:0052192 | 0.01 | 1.85 | 16.31 | 25 | 69 | movement in environment of other organism involved in symbiotic interaction | AXL, CD4, CD86, SCARB2, CR2, CXADR, DPP4, EPS15, GYPA, ICAM1, IFNA2, ITGA5, ITGAV, ITGB1, KPNA3, PVR, SELPLG, SLC10A1, TRIM21, DYNLT1, TYRO3, UVRAG, TRIM25, VAMP8, CLDN1 |
1289 | GO:0007601 | 0.00 | 1.84 | 31.43 | 48 | 133 | visual perception | ABCA4, ARR3, BBS4, OPN1SW, CACNB4, CHRNB2, CNGA1, COL1A1, COL11A1, CRX, CRYBA1, CRYBA4, CRYGB, EYA4, EFEMP1, GABRR2, OPN1MW, GJA3, GLRA1, GNAT1, GNAT2, GUCA1A, GUCY2F, GUCY2D, IMPG1, KCNJ10, OAT, OPA1, RABGGTA, RABGGTB, OPN1LW, RCVRN, PRPH2, RGR, RPGR, SFRP5, SIX3, TULP1, TULP2, TYR, CLRN1, WFS1, SOX14, UNC119, SLC4A7, GUCA1C, NR2E3, IRX5 |
1290 | GO:0016101 | 0.02 | 1.84 | 13.71 | 21 | 58 | diterpenoid metabolic process | ABCA4, ADH5, ALDH1A3, ALDH3A2, OPN1SW, AKR1C4, CLPS, CRH, GPC4, OPN1MW, GPC3, RBP1, RBP2, OPN1LW, SDC4, SLC12A1, SRD5A1, AKR1C3, DGAT1, SDC3, DHRS9 |
1291 | GO:0007586 | 0.01 | 1.84 | 19.62 | 30 | 83 | digestion | AQP5, CD36, CHRM1, CHRM3, CLPS, COPA, CRH, CTRB1, CTSE, ACE, DRD3, FABP2, GALR1, GHSR, KCNN4, KCNQ1, LIPC, OXTR, P2RX7, SCTR, SGK1, SLC15A1, SLC22A5, SOX9, TRPC1, NR1H2, VIL1, TRPV1, MGAM, LIPG |
1292 | GO:0048534 | 0.00 | 1.84 | 99.73 | 150 | 422 | hematopoietic or lymphoid organ development | ABL1, ABL2, ACTN1, ADAR, ADD1, ALAS2, ANGPT1, ANXA1, ARNT, ATP6AP1, AXL, BAD, BAX, BCL3, BGLAP, PRDM1, BMI1, BMP4, BRCA2, ZFP36L2, BTK, CACNB4, CASP9, RUNX2, CD3D, CD3E, CD4, CD8A, CD28, CD86, TNFSF8, CDK6, CEBPE, CHD2, CHUK, CR2, CREB1, CRKL, CSF1R, CTLA4, ACE, EGR3, EPHA2, EML1, EP300, EPHB3, ETS1, ETV6, PTK2B, FGF3, FLT3, FLT3LG, FSHB, FSHR, GPC3, GNAS, HCLS1, HHEX, ONECUT1, IFI16, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, RBPJ, IHH, IL2RA, IL10, IL12B, INHA, IRF1, ITGA4, ITGB1, JARID2, JUN, KDR, KIT, LTF, KITLG, PIP4K2A, PRKX, PTPN6, RAF1, RAG1, RAG2, RARA, RB1, REST, RHAG, RPL22, RPS19, SATB1, SLC8A3, SOS2, SP1, SRF, STAT5B, STAT6, ADAM17, TAL1, TAZ, KLF10, TOP2A, TPD52, TSC1, TNFSF4, TYR, TYRO3, TYROBP, WNT1, XRCC5, ZNF16, FZD5, HIST1H4I, PICALM, FZD7, FZD8, FZD9, GFI1B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, OGT, PIR, AP3B1, RIPK1, TNFSF9, RIPK2, INPP4B, ARHGEF7, AP3D1, TNFSF18, CCNB2, GPR55, KLF4, SOX13, ZBTB24, GAB2, BCL2L11, WASF2, RNF41, DHRS2, PRG4 |
1293 | GO:0030217 | 0.03 | 1.84 | 11.74 | 18 | 50 | T cell differentiation | ABL1, ABL2, BCL3, RUNX2, CD4, CD8A, TNFSF8, CTLA4, FLT3, IFNA2, IRF1, KIT, RPL22, SATB1, STAT6, TSC1, TNFSF18, SOX13 |
1294 | GO:0045740 | 0.04 | 1.84 | 11.11 | 17 | 47 | positive regulation of DNA replication | ATR, ATRX, BMP4, CDK2, DKC1, IGF1, IGF1R, INS, JUN, KITLG, NVL, PCNA, PRKCQ, RAC1, SHC1, AURKB, KLF4 |
1295 | GO:0031400 | 0.00 | 1.84 | 34.78 | 53 | 148 | negative regulation of protein modification process | BUB1B, TSPO, CDC20, CDC27, CENPF, CRY2, DLG2, DLG3, DNMT1, DNMT3B, FYN, DNAJB2, JARID2, LIMK1, PRKCE, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, RPS3, SET, TRIM21, TTK, UBB, USP4, WNT1, ZNF207, AKAP1, CDC23, CDC16, ZW10, ATG5, PSMF1, TMEM59, BAG5, BAG4, KDM4A, FARP1, PSME3, PSMD14 |
1296 | GO:0046483 | 0.02 | 1.84 | 14.85 | 23 | 69 | heterocycle metabolic process | BCHE, BLVRA, CTRB1, CYP2A6, CYP3A4, SARDH, DPEP1, G6PC, GIF, GOT2, GRIN2A, HLCS, HNMT, HPX, P4HA1, PAH, ABCD4, SHMT2, SLC34A1, SRD5A1, VNN2, SLC5A6, P4HA2 |
1297 | GO:0019058 | 0.00 | 1.84 | 42.07 | 64 | 179 | viral life cycle | ADAR, CD28, DDX5, DDX6, EP300, ERCC3, FAU, NR5A2, IFI16, ISG20, JUN, KPNA2, KPNA4, LTF, NUP98, OAS3, CHMP1A, PCSK5, PPIB, PPID, RAB1A, RANBP2, REST, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, SLPI, SMARCA4, SP1, SP100, SRPK2, SSRP1, STAU1, TOP2A, USF1, NUP214, AAAS, RPL14, CTDP1, VAPB, RPL23, ATG5, NUP155, NUP93, PDCD6IP |
1298 | GO:0045834 | 0.01 | 1.84 | 17.02 | 26 | 72 | positive regulation of lipid metabolic process | AGTR1, ANXA1, APOH, CREB1, EPHA8, PTK2B, FGFR3, FGR, FLT1, FLT3, GHSR, GPLD1, HTR2C, IFNG, INS, KIT, PRKAA1, PRKCE, PTK2, RAC1, CCL21, SREBF1, TNFRSF1A, NR1H2, NSMAF, RGN |
1299 | GO:0009152 | 0.00 | 1.84 | 27.54 | 42 | 117 | purine ribonucleotide biosynthetic process | ABCA1, ACACB, ADSS, AK1, AK2, AMPD1, AMPD2, APRT, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, AVPR2, CALM3, CRH, DRD3, DRD5, LPAR1, EDNRA, FSHR, GALR1, GCG, GHRHR, GNAS, LDHC, NTRK2, P2RY11, PALM, PFAS, RAF1, STAT3, VIP, VIPR2, WFS1, PAPSS1, AKAP6, GABBR2, AKAP12, SLC25A13 |
1300 | GO:0090287 | 0.03 | 1.84 | 11.76 | 18 | 50 | regulation of cellular response to growth factor stimulus | ACVRL1, XIAP, BMP4, BMPR2, CAV3, RUNX2, CD63, FGF4, GATA4, GATA6, GPC3, RBPJ, ILK, ING2, OTX2, SOX11, ADAMTS3, FGFBP1 |
1301 | GO:0015850 | 0.00 | 1.84 | 29.54 | 45 | 125 | organic hydroxy compound transport | ABAT, ABCA1, ABCA2, ACACB, AGTR1, AGTR2, ALB, AQP5, AQP6, TSPO, CD36, AKR1C4, CHRNB2, CLU, CNR1, CPT1B, CPT2, CRH, DRD3, GALR1, FFAR3, LCAT, LIPC, OSBP, OXTR, P2RX1, PCP4, PTGS1, RAB3B, RXRA, SEC14L1, SLC10A1, SLCO1A2, SLC22A1, SLC22A3, SLC22A2, SLC22A5, SNCA, NR1H2, SLC10A3, SLC16A6, SLC16A5, SLC9A3R1, LIPG, NR1H4 |
1302 | GO:0048568 | 0.00 | 1.83 | 50.81 | 77 | 215 | embryonic organ development | ALDH1A3, ALX3, ARNT, ASCL2, ATP2B2, BBS4, BCR, PRDM1, BMP4, BMPR1A, RUNX2, CDX2, COL11A1, DLX5, EFNA1, EPHA2, EPHB2, ERCC3, FBN1, EFEMP1, FGF3, FLT3LG, FZD2, GATA4, GNAS, GRB2, HHEX, HMX2, HOXC11, HOXD9, HOXD10, RBPJ, IHH, IL10, INSIG1, ITGA4, KDR, KIT, LLGL2, SMAD3, KITLG, OTX1, OTX2, PCSK5, RAC1, RAD23B, RARA, RARB, RBBP6, RPL38, RYR2, SALL1, STIL, SIX3, SNAI1, SOX9, SOX11, SP1, SRF, ST14, TAL1, NR2F2, TULP3, CLRN1, KDM6A, WNT1, WNT11, ZIC1, FZD5, FZD6, HESX1, NRP1, SOCS3, SLC9A3R1, HAND1, EIF4A3, IRX5 |
1303 | GO:0009615 | 0.00 | 1.83 | 54.83 | 83 | 232 | response to virus | ADAR, ANXA5, BIRC3, ARF1, BAD, BCL2L1, BCL3, BNIP3L, BST2, CD4, CD8A, CD28, CD86, CD37, CDK6, CHUK, AP1S1, AP2S1, CLU, COX8A, CXADR, DDX1, DMBT1, FGF7, FGR, FYN, GABRA5, HMGA1, HSPB1, IFI16, IFIT1, IFIT3, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNGR1, IFNW1, IL2RA, IL12B, IRF1, IRF5, ISG20, KCNJ8, KCNQ1, NTHL1, OAS3, PCBP2, PDK4, PENK, PEX13, PPM1B, PSMA2, RAC1, SCN1A, CCL22, XCL1, SEC14L1, SNRPD1, STAT2, TPT1, TNFSF4, TRIM25, ZNF189, FOSL1, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, IKBKG, AP1M1, HIST1H3F, DDX21, CHST3, NUP93, PHYHIP, FGFBP1, BCL2L11, AP1M2, ABCC9 |
1304 | GO:0043473 | 0.02 | 1.83 | 14.42 | 22 | 61 | pigmentation | ARCN1, BAX, BBS4, CD63, EDA, EN1, GNAQ, IHH, KIT, KITLG, PAX3, RAB1A, RAB27A, SOX10, TYR, ATRN, AP3B1, AP1M1, AP3D1, ZEB2, BCL2L11, ATP6AP2 |
1305 | GO:0050803 | 0.00 | 1.83 | 33.56 | 51 | 142 | regulation of synapse structure or activity | APP, ARF1, ATP2B2, ADGRB2, CAMK2A, CDC20, CHRNB2, CREB1, CRH, CTNND2, CX3CR1, DBI, DRD5, EFNA5, EGR2, EPHB1, EPHB2, EPHB3, ETV5, PTK2B, GFAP, GHSR, GRIA1, GRIN2A, HRH1, KCNJ10, KIT, NTRK2, NTRK3, OXTR, P2RX3, PTEN, PTK2, PTN, RARA, SLC8A3, SNAP25, SNCA, SRF, STAU1, SYP, CNTN2, TNR, TPBG, DGKI, NRXN3, NRXN1, PICK1, RIN1, RAPGEF2, FRMPD4 |
1306 | GO:0051783 | 0.00 | 1.83 | 24.34 | 37 | 103 | regulation of nuclear division | BIRC5, ATRX, BMP4, BUB1B, CCNB1, CD28, CDC20, CDC25C, CDC27, CENPE, CENPF, CHEK1, CSNK2A1, CSNK2A2, DAPK3, DRD3, DUSP1, FGFR3, GPR3, IGF1, IGF1R, IGF2, IL1A, INS, CHMP1A, PRKAR1A, PTEN, RB1, TTK, ZNF207, CUL3, CDC23, CDC16, ZW10, MAD2L1BP, DLGAP5, CUL7 |
1307 | GO:1901606 | 0.02 | 1.82 | 15.13 | 23 | 64 | alpha-amino acid catabolic process | AHCY, ARG1, ASL, AUH, CDO1, GAD1, GLDC, GLUD1, GOT2, GPT, GSTZ1, HNMT, IDO1, IVD, OAT, OGDH, PAH, QDPR, SHMT1, TAT, DDO, ALDH4A1, KYNU |
1308 | GO:0002478 | 0.00 | 1.82 | 25.05 | 38 | 106 | antigen processing and presentation of exogenous peptide antigen | ARF1, CANX, CD36, CENPE, AP1S1, AP2S1, CTSE, CYBA, DYNC1H1, DNM2, ITGAV, KIF5A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, UBB, DYNLL1, CTSF, AP1M1, KIF3B, PSMF1, AP1M2, PSME3, PSMD14 |
1309 | GO:0072599 | 0.01 | 1.82 | 18.43 | 28 | 78 | establishment of protein localization to endoplasmic reticulum | FAU, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, RYR2, SRP9, SRP14, RPL14, RPL23 |
1310 | GO:0030855 | 0.02 | 1.82 | 15.75 | 24 | 68 | epithelial cell differentiation | NR0B1, ALDOC, CAPN5, CBR1, CD63, TPP1, CNN3, DLX5, DMBT1, NR5A2, FZD2, IFNG, JUN, MGMT, PCNA, PRKX, STAT5B, UPK1B, UPK2, UPK3A, VIL1, TAGLN2, CBFA2T2, DHRS9 |
1311 | GO:0042180 | 0.00 | 1.82 | 33.04 | 50 | 140 | cellular ketone metabolic process | ACACB, ANXA1, BHMT, CBR1, AKR1C4, CNR1, COMT, CYP11B1, GCG, KAT2A, GHSR, GOT2, HMGCR, IDO1, INS, INSIG1, OAZ1, OAZ2, OXCT1, PDK4, PRKCE, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, REST, SNCA, SREBF1, NR1H2, PDHX, KYNU, RGN, EIF2AK3, PSMF1, NR1H4, PSME3, PSMD14 |
1312 | GO:0051223 | 0.00 | 1.82 | 51.04 | 77 | 218 | regulation of protein transport | ABAT, ABL1, ABL2, ALOX15B, ANG, ANXA1, ANXA5, ARF1, ARL2, ARNTL, BAD, BLK, CACNA1A, CASP5, CD58, CHRM3, CNR1, CRH, CRP, CSF1R, DRD3, EFNA5, EPHA5, F2R, FBLN1, FGA, FGR, GCG, GHSR, GLUD1, GNAS, GPLD1, FFAR1, HMGCR, FOXA2, IFNA2, IFNG, IL1A, IL13, INS, ISL1, ITPR1, KCNC2, KCNJ11, KCNN4, KCNS3, LLGL2, OXCT1, P2RX7, PAEP, PAM, PPID, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, REST, RFX3, CX3CL1, SNAP25, SYT5, TRAF2, TRPM2, TSG101, TNFSF4, NR1H2, ARHGEF5, SYT7, IL1RL1, HMGN3, NRXN1, ATG5, CLOCK, NR1H4 |
1313 | GO:0006366 | 0.02 | 1.82 | 13.73 | 21 | 61 | transcription from RNA polymerase II promoter | BTF3, CSTF3, ERCC6, HIVEP2, HLF, SRSF1, SRSF5, SRSF7, SNAPC3, SNRPE, SNRPF, SSRP1, ZNF141, PIR, SRSF9, TAF1A, DDX21, TRIP11, TBPL1, ZNF516, RBM8A |
1314 | GO:0009199 | 0.00 | 1.82 | 25.76 | 39 | 109 | ribonucleoside triphosphate metabolic process | AK1, AK2, ALDOC, AMPD2, ARNT, ATP1A2, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1B2, ATP6V0A1, BAD, TSPO, COX8A, COX15, CTNS, ENO2, GAPDH, IGF1, INS, LDHC, OGDH, P2RX7, PGAM1, PPP2R5D, PRKAA1, PRKAG1, SDHC, SNCA, STAT3, TAZ, UQCRC1, UQCRC2, UQCRH, OGT, SLC25A13 |
1315 | GO:0030278 | 0.00 | 1.81 | 22.45 | 34 | 95 | regulation of ossification | ACVR2B, ATP6AP1, BGLAP, BMP4, BMPR1A, BMPR2, RUNX2, CDK6, DDX5, DLX5, ECM1, S1PR1, EGR2, PTK2B, GNAS, HGF, IGF1, RBPJ, ILK, JUND, LTF, SMAD1, SMAD3, OMD, P2RX7, P2RY2, PRKD1, PTK2, SOX9, SOX11, FGF23, TP63, CHRD, PDLIM7 |
1316 | GO:0001890 | 0.01 | 1.81 | 19.14 | 29 | 81 | placenta development | ANG, ARNT, ASCL2, PRDM1, BMPR2, BSG, CCNF, CDX2, DCN, GHSR, GRB2, RBPJ, IL10, ITGA4, LLGL2, SERPINE1, PTGIS, PTK2, RXRA, SNAI1, SP1, ST14, STC1, NR2F2, FZD5, FOSL1, SOCS3, HAND1, CUL7 |
1317 | GO:0006090 | 0.03 | 1.81 | 12.53 | 19 | 53 | pyruvate metabolic process | ALDOC, ARNT, BSG, ENO2, GAPDH, IGF1, INS, LDHC, OGDH, P2RX7, PCK1, PDK4, PGAM1, PPP2R5D, PRKAA1, PRKAG1, STAT3, PDHX, OGT |
1318 | GO:0001817 | 0.00 | 1.81 | 26.40 | 40 | 113 | regulation of cytokine production | BIRC3, ARNT, ATF4, C3, CD6, CD36, CHUK, CLC, CLU, CREB1, CYBA, EP300, FLT4, GATA4, FFAR3, IL12RB2, IL18, IRAK1, IRF5, P2RY2, SERPINE1, PDE4B, SEC14L1, TRIM21, STAT6, ADAM17, TRAF2, XRCC5, FZD5, IKBKG, SERPINB7, RIPK1, TNFSF9, RIPK2, ARHGEF2, EIF2AK3, IL27RA, LITAF, TRIL, ATP6AP2 |
1319 | GO:1901564 | 0.00 | 1.81 | 89.65 | 134 | 392 | organonitrogen compound metabolic process | ACPP, ACY1, ALDOC, ARNT, ARSA, STS, ARSD, ARSE, ARSF, ATP1A2, ATP2B2, ATP6V1B2, AUH, BAD, BAX, BCHE, BCKDHA, BLVRA, CACNA1A, CACNB4, CAT, CD44, CHRNB2, COMT, COX8A, CRAT, CTRB1, CYP3A4, DBI, DBT, DLG2, DLG3, SARDH, DNMT1, DNMT3B, ENO2, FZD2, G6PC, GALC, GALNS, GIF, GLDC, GM2A, GPLD1, GRIN2A, HEXB, HGF, HLCS, HMGCR, HNMT, HPX, IDS, IDUA, INS, ITIH1, ITIH4, IVD, KIT, LIPC, MDH2, NTHL1, OGDH, OVGP1, P4HA1, PDE4B, PDE8A, PEPD, PGAM1, PIM1, PPP2R1A, PPP2R5D, PRKAG1, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTGDR, PTGIS, ABCD4, RPE, RRM1, SDHC, SFTPB, SLC6A6, SLC7A4, SLC9A1, SLC34A1, SLC22A5, SNCB, SRD5A1, STAT5B, SULT1E1, SULT1A3, SULT1C2, SULT2B1, SUOX, TACR3, TAT, TAZ, TYR, UNG, UQCRC1, UQCRC2, UQCRH, PDHX, SLC7A5, OGT, DDO, PDE5A, VNN2, SLC5A6, MBD4, P4HA2, PSMF1, TP53I3, SNCAIP, SPOCK2, NR1H4, PSME3, PSMD14 |
1320 | GO:0045619 | 0.01 | 1.81 | 16.52 | 25 | 70 | regulation of lymphocyte differentiation | ANXA1, AXL, BMP4, CD28, CD86, CTLA4, EGR3, FLT3LG, IFNA2, IFNG, IHH, IL2RA, IL12B, IRF1, RAG1, RARA, SOS2, TNFSF4, AP3B1, TNFSF9, RIPK2, AP3D1, TNFSF18, SOX13, RNF41 |
1321 | GO:0000003 | 0.00 | 1.81 | 56.47 | 85 | 245 | reproduction | ALOX15B, ARHGDIB, ARNT, STS, ASCL2, BMPR1A, BOK, BYSL, CCNF, CD44, CDC20, CDK2, CDX2, COL9A3, CRH, CRHBP, DCN, EPYC, DUSP1, EMP2, ERCC4, FBLN1, GATA6, GNAS, GOLGA2, GPR3, GRB2, IDH1, IGF1R, IGF2, RBPJ, IL10, IDO1, INSRR, ITGA4, LLGL2, NUMA1, SERPINE1, PCSK5, SERPINB5, PRKACB, PRKAR1A, PSAP, PSG2, PSG3, PSG5, PSG6, PSG9, PSG11, PTGDR, PTK2, PZP, RAD21, RAD51, RAD51B, RAD51D, RRM1, SALL1, SNAI1, SRD5A1, SRY, ST14, SULT1E1, TOP2A, TOP2B, TUBG1, UBB, SCGB1A1, XRCC2, FZD5, SMC1A, AKR1C3, ADAM15, CDKL2, SOCS3, SMC3, EXO1, ZW10, HAND1, CUL7, SMC4, ACTR2, RAD50, FEM1B, IRX5 |
1322 | GO:0032504 | 0.00 | 1.81 | 100.20 | 149 | 424 | multicellular organism reproduction | NR0B1, ANG, ANGPT2, ANXA1, BIRC3, ARG1, ARNTL, ATRX, AXL, BAD, BAX, BBS4, BCL2L1, PRDM1, BMP4, BMPR2, BRCA2, BRDT, BSG, CAPN5, CASP5, CCNB1, CCNE1, CD9, CDC25C, CHAT, CLU, CNR1, COMT, CTNNA1, CXADR, CYLC1, CYLC2, DAZ1, DBH, ACE, DIAPH2, DNM2, DRD5, EDNRA, PHC2, ETS1, ETV5, PTK2B, FANCF, FANCG, FGF7, FSHB, CENPI, FSHR, GATA4, GDF9, B4GALT1, GHRHR, GHSR, GNAQ, HIST1H1T, HIST1H1A, HEXB, HPGD, ICAM1, IGF1, IHH, IL1A, IL1R1, ING2, INHA, ITGB1, KDR, KISS1, KIT, KRT9, SMAD1, SMCP, KITLG, ODF1, OVGP1, OVOL1, OXTR, P2RX1, P2RY2, PAM, SERPINA5, SERPINF1, PGR, PPP2R1A, PRKACG, PRKAG1, PTAFR, PTEN, PTGIS, PTN, PTPRN, RAD23B, RAD51C, RARA, RPS6KB1, RXRA, SBF1, SMARCA2, SMARCA4, SOX3, SOX9, SP1, SPAG4, SPAM1, STAT5B, STC1, STYX, TAF4B, TBP, NR2F2, NR2C2, TRPM2, TSPY1, TYRO3, UBE3A, VIP, YY1, ZNF35, ZNF148, FOSL1, NRIP1, USP9X, USP9Y, FZD4, TPST2, FKBP6, DDO, RUVBL1, TP63, PDE5A, DYNLL1, EIF2B2, EIF2S2, HERC2, RNF8, RGN, FAM50A, SLIT2, PICK1, ADAMTS2, TBPL1, CLOCK, SPAG6, SPATA2, REC8, BCL2L11, AKAP9 |
1323 | GO:1901700 | 0.00 | 1.81 | 22.22 | 34 | 103 | response to oxygen-containing compound | ACVR2B, ALDH3A2, ANGPT2, ATP5G3, BRCA2, DAGLA, CD4, CD9, CHAT, COL6A2, CTSH, DBH, ERCC6, GJA3, GOT2, GPX1, GPX2, GYS2, HBA2, HLCS, HP, IHH, KPNA4, OLR1, PAM, PPP2CB, SP100, NR2F2, TRPM2, PRDM2, SLC14A2, SLC10A3, MBD4, GPR55 |
1324 | GO:0048738 | 0.02 | 1.80 | 13.88 | 21 | 59 | cardiac muscle tissue development | BMP4, COL11A1, KAT2A, ISL1, ITGB1, SMAD7, PLN, PTEN, RARA, RARB, RXRA, RYR2, SGCB, SLC9A1, SRF, TAZ, TNNC1, TNNI3, TSC1, HAND1, ATG5 |
1325 | GO:0050896 | 0.00 | 1.80 | 23.10 | 36 | 132 | response to stimulus | AMPD1, ANXA11, ATP12A, ATP4A, ATP5G3, ENTPD6, CPOX, CRX, CYB5A, EMX1, EMX2, GAD1, GOT2, GYS2, PFAS, ABCD3, SCN8A, SCNN1A, SCNN1G, SEPW1, SLC22A1, SLC22A2, SLC22A5, SRP14, TBCE, TNNC1, TOP1, CLRN1, SLC30A2, SLC10A3, SLC25A12, PER3, CTDP1, SLC22A8, SLC25A13, IRX5 |
1326 | GO:0030099 | 0.00 | 1.80 | 29.19 | 44 | 124 | myeloid cell differentiation | ATP6AP1, BGLAP, CD86, CEBPE, CHUK, CREB1, CSF1R, EPHA2, PTK2B, FSHB, FSHR, GPC3, GNAS, HHEX, IFI16, IFNG, RBPJ, IL12B, JUN, LTF, KITLG, PIP4K2A, PRKX, RARA, KLF10, TYROBP, HIST1H4I, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, OGT, PIR, RIPK1, TNFSF9, INPP4B, GPR55, GAB2, WASF2, RNF41, DHRS2 |
1327 | GO:0030516 | 0.03 | 1.80 | 13.23 | 20 | 56 | regulation of axon extension | ABL1, ARHGAP4, BMPR2, DNM2, CTTN, GOLGA4, NRG1, ILK, LIMK1, NRCAM, NTRK3, RNF6, SEMA3F, SRF, TNR, SEMA3B, NRP1, SLIT2, AATK, SEMA3E |
1328 | GO:0045596 | 0.00 | 1.80 | 78.46 | 117 | 332 | negative regulation of cell differentiation | ABCA1, ACVRL1, NR0B1, ANXA1, APP, ARHGAP4, ARNTL, ASCL1, ASCL2, BMP4, BMPR1A, ZFP36L2, TSPO, CAV3, CDK6, CRP, CTLA4, CTNNA1, DCC, DDX6, DPYSL3, DRD3, LPAR1, EFNA1, EIF4E, F2, PTK2B, FBLN1, EFEMP1, FGFR3, FLT3, GDI1, GFAP, NRG1, FOXA2, IAPP, IFNA2, IFNG, IGF1, RBPJ, IHH, IL13, IL18, INHA, INSIG1, IRF1, ISL1, ITGAV, ITGB1, LTF, SMAD3, SMAD7, FOXO4, YBX1, NTRK3, PCM1, PTEN, PTK2, PTN, RAP1GAP, RARA, RARB, REST, RNF6, SORT1, SALL1, SEMA3F, SIX3, SNAI1, SOX3, SOX9, SOX11, SPOCK1, STAT3, STAT5B, CNTN2, DYNLT1, TNR, TP73, TTC3, TNFSF4, NR1H2, VIM, TRPV1, WNT1, SEMA3B, FGF23, HIST1H4I, FZD7, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, TP63, CHRD, INPP4B, NRP1, PHOX2B, TNFSF18, ARHGEF1, CBFA2T2, CTDP1, ARHGEF2, ITGB1BP1, GPR55, SLIT2, BAG5, CXCL14, AATK, RAPGEF2, SEMA3E, KIAA0319, RNF10, OLIG2 |
1329 | GO:0050769 | 0.00 | 1.80 | 43.96 | 66 | 186 | positive regulation of neurogenesis | ABL2, ARF1, ASCL1, BMP4, BMPR2, TSPO, CNR1, CRX, CX3CR1, BRINP1, DNMT3B, DPYSL3, LPAR1, EFNA5, ETV5, PTK2B, FYN, GFAP, GOLGA4, RAPGEF1, HGF, NRG1, FOXA2, IFNG, ILK, ITGB1, KIT, LIMK1, CAPRIN1, NRCAM, NTRK2, NTRK3, OPA1, P2RY2, PALM, PCP4, SERPINF1, PRKCI, PRKD1, PTN, RARA, RARB, RHEB, SALL1, CX3CL1, SGK1, SMARCD3, SOX10, SOX11, SRF, SYT1, SYT4, TP73, XRCC2, XRCC5, RNF112, RND2, NUMB, NRP1, PHOX2B, CBFA2T2, SLIT2, RAPGEF2, RIMS2, CUL7, OLIG2 |
1330 | GO:0046649 | 0.00 | 1.80 | 26.49 | 40 | 114 | lymphocyte activation | ABL2, BCL3, ZFP36L2, BST2, RUNX2, CD7, CD8A, TNFSF8, CDK6, CXADR, EP300, EPHB1, PTK2B, HHEX, ONECUT1, ICAM1, RBPJ, INS, ITGA4, ITGB1, KIT, SMAD3, RAB27A, RPL22, SRF, ADAM17, TPD52, TSC1, LAT2, WNT1, FZD5, FZD7, FZD8, FZD9, STX11, RNF8, EXO1, IL27RA, SOX13, RNF41 |
1331 | GO:0007204 | 0.04 | 1.80 | 11.89 | 18 | 51 | positive regulation of cytosolic calcium ion concentration | ABL2, ADRA1B, AVPR1B, CACNA1A, CAV3, CD36, CD52, CCR3, CCR8, GALR1, GNA15, GNAT2, GNG3, KNG1, OXTR, P2RY2, P2RY4, S1PR4 |
1332 | GO:0060491 | 0.01 | 1.80 | 17.24 | 26 | 73 | regulation of cell projection assembly | BBS4, DNM2, DPYSL3, EPHA2, GPM6A, HRG, ICAM1, KIT, P2RX7, PALM, PFN2, PRKCQ, RAB5A, RAC1, RAC2, RALA, CCL21, SRF, CLRN1, WNT1, SLIT2, NRXN1, ATG5, IFT140, ARPC2, WASF2 |
1333 | GO:0051091 | 0.04 | 1.80 | 11.25 | 17 | 48 | positive regulation of sequence-specific DNA binding transcription factor activity | ANXA3, EP300, EPHA5, FZD2, IL10, KIT, PTEN, SMARCA4, SP100, SRF, TRIM21, WNT1, ARHGEF5, FOSL1, FZD4, BUD31, RNF41 |
1334 | GO:0050863 | 0.02 | 1.80 | 15.24 | 23 | 65 | regulation of T cell activation | BAD, CD3D, CD3G, CD5, CTLA4, DPP4, EGR3, FLOT2, FYN, GRB2, IFNA2, RAC1, RAG1, RARA, CCL21, TRAF2, VAV1, AP3B1, TNFSF14, AP3D1, SOCS6, GRAP2, SOX13 |
1335 | GO:0060627 | 0.00 | 1.80 | 55.54 | 83 | 235 | regulation of vesicle-mediated transport | ABL1, ABL2, ANGPT1, ANXA1, ARF1, ATP6AP1, AXL, BCR, BICD1, BLK, C3, CACNA1A, CAV3, CBL, CD36, CD63, AP2S1, CYBA, DNM1, DNM2, FGA, FGR, GAS1, B4GALT1, GPC3, GLRA1, HIP1, IFNG, IL13, IL13RA2, INSIG1, ITGAV, ITGB1, SERPINE1, PFN2, SEPT5, PRKAA1, PRKD1, PTAFR, PTEN, RAB3B, RAB4A, RAB5A, RAB5B, RAB27A, RAC1, RAC2, RALA, RAP1GAP, REST, CCL21, SDC4, SELE, SFTPD, SNCA, SPINK1, STXBP2, STXBP3, SYN1, SYT1, SYT4, TSG101, TULP1, NR1H2, UVRAG, VTN, PICALM, VAMP8, NRP1, SYNJ1, SYT7, UNC119, RAB9A, PICK1, GOSR1, RIMS2, ZFYVE16, SNX17, DNAJC6, GAB2, C2CD5, SNAP91, PDCD6IP |
1336 | GO:0010629 | 0.00 | 1.79 | 29.85 | 45 | 130 | negative regulation of gene expression | ACACB, ANG, BIRC3, XIAP, ATF4, BARD1, BBS4, CCNB1, CD3E, CD28, CD59, CDKN1A, CIRBP, CRH, CTGF, DAPK3, EIF4E, EPRS, FLOT2, FYN, GAPDH, GAS1, GRB7, INPPL1, EIF3E, CAPRIN1, SERPINE1, SERPINF1, PGR, UPF1, RPS3, SRSF7, SFSWAP, SRP9, TSC1, VEGFB, PICALM, EIF4EBP3, SRSF9, EIF2B3, SLIT2, EIF2AK3, TMEM59, EIF4A3, RNF40 |
1337 | GO:0006310 | 0.00 | 1.79 | 31.30 | 47 | 133 | DNA recombination | ABL1, ACTL6A, ATR, ATRX, BARD1, BRCA2, CD28, CDK2, CHEK1, ERCC4, IFNG, RBPJ, IL10, KPNA1, KPNA2, TONSL, PPP4C, RAD21, RAG1, RAG2, SFPQ, STAT6, SUPV3L1, TOP2A, TOP2B, TSN, TNFSF4, UBB, SUMO1, UNG, XRCC5, YY1, HIST1H4I, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, RUVBL1, HERC2, RNF8, EXO1, RECQL5, IL27RA, REC8, PSMD14 |
1338 | GO:0008219 | 0.00 | 1.79 | 76.88 | 115 | 346 | cell death | ACTN1, ADD1, ALK, ALOX15B, ALX3, ANXA6, APP, ATP2A1, BMP1, BMP3, BMP8B, BMPR2, BRCA2, BTK, BUB1B, CASP5, CD3E, CD3G, CD5, CD28, TNFSF8, CD70, CDK11B, CDH1, CLC, CSE1L, CSNK2A2, BRINP1, DBH, DCC, DDX5, DNASE1, DNASE1L3, EPHA2, EIF4G2, EIF5A, EMP2, EP300, EPHB1, ERCC6, ETS1, EYA2, FLT3, GAPDH, GAS1, GAS2, GDF9, GNGT1, GRID2, GZMH, HIC1, UBE2K, IAPP, IFI16, IFNA2, IL2RA, INHA, IRF1, ITPR1, JUND, KPNA1, MEOX2, OLR1, P2RX4, PAEP, PAX3, PPP2CB, PRKCE, PTPN6, PTPRH, RAD21, RB1, DPF2, RYR2, SATB1, SCN2A, SFRP5, SHB, SIX3, SP100, STK10, ADAM17, TNFRSF1A, TNFRSF1B, TOP1, TRAF1, TSC1, VIM, XPA, FZD5, DPF1, DYRK2, CUL4A, CUL3, CUL2, CUL1, RGS20, TNFSF9, RABEP1, BCL7C, BCL7B, SLC4A7, LITAF, GDF15, BCAR1, TRAF4, AATK, SNCAIP, SLK, KIAA0141, OXSR1, PDCD6IP, SGK2, FEM1B, RNF41 |
1339 | GO:0006605 | 0.00 | 1.79 | 94.53 | 140 | 400 | protein targeting | ACTL6A, ADAR, AGTR2, ANGPT1, ARNTL, RERE, BCL3, BMP4, BMPR1A, BNIP3L, BSG, TSPO, CBLB, CD36, SCARB2, CDH1, CDKN1A, CSE1L, CSNK2A2, CTSK, EDA, F2R, FAU, FYB, KAT2A, GDI1, GFER, GNAQ, GOLGA4, GPR26, HCLS1, NRG1, HNMT, HSPA4, HSPA9, IFNG, IGF1, IL10, IL12B, IL18, JUN, KPNA1, KPNA2, KPNA3, KPNA4, IPO5, LTBP2, SMAD3, TONSL, NUP98, PRDX1, PALM, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PPM1B, PRKCI, PRKCQ, PEX19, PEX5, RAB6A, RAB27A, RAC2, RAN, RANBP2, RNASE2, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, SFRP5, SIX3, SLC9A1, SREBF1, SRP9, SRP14, STAT3, TRIP6, UBE2L3, YWHAZ, ZIC1, ZBTB17, FZD5, NUP214, AKAP1, BAP1, FZD7, DYRK2, OGT, AP3B1, RGS20, RUVBL1, AKR1C3, TNFSF14, CDKL2, RPL14, RASSF9, ITGB1BP1, TRIP11, RPL23, SLC9A3R1, ZFYVE9, PEX16, PICK1, AKAP6, LITAF, BAG4, AKAP12, NUP155, IPO13, NUP93, ZFYVE16, ATG13, TOMM20, C2CD5, FAM20B, AP1M2, SAE1, NUTF2 |
1340 | GO:0042100 | 0.05 | 1.79 | 10.63 | 16 | 45 | B cell proliferation | ABL1, BAX, PRDM1, CDKN1A, CHRNB2, CR2, CTLA4, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IL10, IL13, RAG2 |
1341 | GO:0031329 | 0.00 | 1.79 | 32.67 | 49 | 140 | regulation of cellular catabolic process | APOH, ARAF, ZFP36L2, CAV3, CLU, CSNK1D, PTK2B, GPX1, UBE2K, DNAJB2, IDH1, SMAD7, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, RAD23B, RB1, UPF1, SKP1, SUMO3, SUPV3L1, TNFRSF1B, UBB, UBE3A, SUMO1, CUL3, CUL1, GTPBP1, RNF14, DLGAP5, RNF40, PSME3, PSMD14 |
1342 | GO:1902680 | 0.00 | 1.79 | 176.78 | 257 | 748 | positive regulation of RNA biosynthetic process | ACVRL1, AGTR2, ALK, ANXA3, APP, PHOX2A, ARNT, ARNTL, ASCL1, ATF4, RERE, ATRX, BACH1, BCL3, BMP3, BMP4, BMPR1A, BMPR2, BRCA2, BRDT, KLF5, BTK, CAMK2A, CAT, RUNX2, CCNC, CCNE1, CCNT2, CD3D, CD28, CD86, TNFSF8, CDH1, CDK2, CDK8, CDX2, CEBPE, CHEK1, CHUK, CLU, COL1A1, CREB1, CRX, CTH, DCN, DDX5, DLX5, DNM2, DRD3, ARID3A, EBF1, EDA, S1PR1, EGR2, ELK1, EN1, EP300, EPHA5, ERCC3, ERCC6, ESRRG, ETS1, ETV4, ETV5, ETV6, EVX1, EZH1, F2R, FGF4, FGF7, FSHB, NR5A2, FZD2, GALR1, GATA4, GATA6, GCG, KAT2A, HCLS1, HEXB, HGF, NRG1, HHEX, HMGN1, HMGA1, NR4A1, FOXA2, HNF4G, ONECUT1, HOXC11, HOXD8, HOXD9, HOXD10, HSF4, ICAM1, IFI16, IFNA2, IFNG, IGF1, IGF2, RBPJ, IHH, IL1A, IL10, ILK, ING2, INS, INSIG1, IRAK1, IRAK2, IRF1, IRF5, ISL1, JUN, JUND, KIT, LMO1, LTF, SMAD1, SMAD3, SMAD7, SMAD9, MEOX2, CIITA, AFF1, FOXO4, PPP1R12A, YBX1, OTX1, OTX2, SERPINE1, PAX3, PAX9, PCK1, PGR, PHF2, PRKCI, PRKD1, PRKCQ, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PTEN, RAD21, RAF1, RAN, RARA, RARB, RB1, REST, RFX3, RFXAP, RLF, RNF6, RPS3, RPS6KA1, RXRA, RXRG, S100A8, S100A9, S100A12, SALL1, SIX3, SLC9A1, SMARCA1, SMARCA2, SMARCA4, SMARCD3, SNAI1, SOX9, SOX10, SOX11, SP1, SP100, SREBF1, SRF, SRY, TRIM21, SSRP1, STAT3, STAT4, STAT5B, STAT6, TAF7, TAL1, TBL1X, TBP, HNF1A, NR2F2, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C2, TRAF1, TRAF2, UBB, UBE3A, NR1H2, USF1, WNT1, WNT11, YY1, ZIC1, CNBP, ZSCAN21, TRIM25, ZNF148, ZBTB17, ZXDA, FZD5, ARHGEF5, FOSL1, FGF23, NRIP1, PICALM, FZD4, FZD7, FZD8, OGT, IKBKG, STK16, KLF7, TP63, TRADD, RIPK1, RIPK2, BUD31, PHOX2B, RPS6KA4, TNFSF18, BAZ1B, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, CCPG1, ITGB1BP1, KLF4, HMGN3, HAND1, EIF2AK3, FHL5, ONECUT2, CLOCK, RNF14, ZNF516, ARHGEF11, ZEB2, RNF10, NR1I3, NR1H4, NR1D2, NR2E3, RNF41 |
1343 | GO:0007167 | 0.00 | 1.78 | 35.22 | 53 | 157 | enzyme linked receptor protein signaling pathway | ACVR2B, ACVRL1, XIAP, BMP1, BMP3, BMP4, BMP8B, BMPR1A, CAV3, CCNC, CCNT2, CDK8, CTF1, DLX5, DNM2, FBN1, FSHB, FUT8, GATA4, GATA6, GDF9, GPC3, GUCY2C, GUCY2F, GUCY2D, ONECUT1, HPGD, ILK, ING2, INHA, JUN, LTBP2, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, SERPINE1, PTN, RYR2, SOX11, SP1, KLF10, TTK, VIM, USP9X, USP9Y, CHRD, ZFYVE9, ONECUT2, GDF15, ADAMTSL2, ZFYVE16 |
1344 | GO:1902580 | 0.00 | 1.78 | 57.07 | 85 | 247 | single-organism cellular localization | ACTL6A, ALB, ARCN1, ATP2A1, BBS4, BICD1, BNIP3L, BRCA2, TSPO, CCNB1, SCARB2, CD59, CENPA, CENPE, COPA, CSNK1D, CSNK2A2, CTSK, DYNC1H1, FGR, KAT2A, GFER, GOLGA2, GPR26, GRIA1, NRG1, HNMT, HSPA9, IL13, IL13RA2, INSIG1, KIT, LLGL2, MAL, NUMA1, OPA1, CHMP1A, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PPP6C, PTEN, RAB1A, RAB6A, RAC2, RB1, RNASE2, S100A13, TRAPPC2, SREBF1, STXBP2, DYNLT1, UBB, UBE2L3, UVRAG, LAT2, ZBTB17, FZD5, BAP1, UXT, CUL3, RUVBL1, USO1, CDC23, CDKL2, ARHGEF2, ZW10, VAPB, COPB2, TRIP11, KIF3B, SEC22B, GOSR2, ZFYVE16, ATG13, DLGAP5, TOMM20, GAB2, FAM20B, SAE1, ACTR2, SPRY1 |
1345 | GO:0051094 | 0.00 | 1.78 | 32.68 | 49 | 143 | positive regulation of developmental process | AGTR2, ANGPT2, ANXA3, ADGRB2, CBLB, CD3E, CD28, CDC20, CCR3, CTSH, DCN, ECM1, EDNRA, EPHB1, EPHB2, EPHB3, F3, FGF3, FGF7, FLT1, HMGCR, HMGA1, HOXC11, HSPB1, IL1A, IDO1, ISL1, ITGA5, OTX2, OXTR, P2RX7, SERPINE1, PRKAA1, PTGIS, SRY, STAT6, TPBG, UNG, VEGFB, WNT1, SERPINB7, TRADD, USP2, NRXN3, NRXN1, RBM19, RNF10, PDCD6, SPRY1 |
1346 | GO:0006818 | 0.01 | 1.78 | 24.11 | 36 | 102 | hydrogen transport | ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP4A, ATP4B, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, COX6A1, COX6B1, COX7A1, COX7C, COX8A, COX15, CYB5A, DRD3, IL13, SLC9A1, SLC9A2, SLC9A3, SLC15A1, UCP1, UQCRC1, UQCRH, ATP6V0D1, SLC9A3R1, ATP6V1G1 |
1347 | GO:0061448 | 0.00 | 1.77 | 24.78 | 37 | 105 | connective tissue development | ACVRL1, BBS4, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, RUNX2, CD44, COL1A1, COL11A1, CTGF, EFEMP1, FGF4, FGFR3, GNAS, GPLD1, HMGCS2, FOXA2, IGF1, IHH, SMAD1, SMAD3, SMAD9, OXCT1, SNAI1, SOX9, SRF, TYMS, UBB, WNT11, SERPINB7, DYRK1B, HAND1, EIF2AK3, ZNF516 |
1348 | GO:0008544 | 0.02 | 1.77 | 16.71 | 25 | 71 | epidermis development | ALDH3A2, STS, CST6, CTGF, DBI, EDA, FGF7, FLOT2, GNAS, IGF1R, KRTAP5-9, KRT5, KRT9, KRT32, KRT34, KRT83, LAMA3, NTF4, OVOL1, RBP2, SATB1, SNAI1, SOX9, FZD6, TRADD |
1349 | GO:0045597 | 0.00 | 1.77 | 67.58 | 100 | 290 | positive regulation of cell differentiation | ABL2, ACVRL1, AGTR1, ALOX15B, ARF1, ARNT, ARNTL, ASCL1, BAX, KLF5, TSPO, CCNE1, CD36, CDX2, CLU, CNR1, COL1A1, CRX, CTGF, CX3CR1, BRINP1, DMBT1, DNM2, DNMT3B, DPYSL3, LPAR1, EFNA5, ETS1, ETV5, PTK2B, FGA, FGFR3, FYN, GATA4, GATA6, GFAP, B4GALT1, GOLGA4, RAPGEF1, FOXA2, HSF4, HTR2C, IL13, INS, ITGB1, KDR, KIT, LIMK1, CAPRIN1, SMAD3, NRCAM, NTRK2, NTRK3, OPA1, P2RY2, PA2G4, PALM, PCP4, SERPINF1, PRKCI, PROC, PTN, RAC1, RAC3, RARB, RFX3, RHEB, RPS6KA1, SALL1, CX3CL1, SGK1, SNAI1, SOX9, SOX10, SRF, SULT1E1, SYT1, SYT4, TAL1, TP73, XRCC2, XRCC5, ZNF16, RNF112, RND2, PTCH2, NUMB, PDE5A, NRP1, ARHGEF7, PHOX2B, SOCS3, CBFA2T2, SLIT2, RAPGEF2, RIMS2, CUL7, ZEB2, ARPC2, OLIG2 |
1350 | GO:0003279 | 0.04 | 1.77 | 12.05 | 18 | 51 | cardiac septum development | PRDM1, BMP4, DNM2, FZD2, GATA4, GATA6, ISL1, SMAD6, SMAD7, PCSK5, RARA, RARB, SALL1, SOX11, WNT11, TRIP11, HAND1, SNX17 |
1351 | GO:1902591 | 0.04 | 1.77 | 12.05 | 18 | 51 | single-organism membrane budding | ARCN1, ARF1, CD59, COPA, CSNK1D, GOLGA2, GRIA1, INSIG1, PPP6C, PRKCI, RAB1A, TRAPPC2, CUL3, USO1, VAPB, COPB2, SEC22B, GOSR2 |
1352 | GO:0010977 | 0.02 | 1.77 | 16.78 | 25 | 71 | negative regulation of neuron projection development | ARHGAP4, DCC, DPYSL3, LPAR1, EFNA1, EFEMP1, GDI1, GFAP, PTEN, PTK2, RNF6, SEMA3F, SPOCK1, TNR, VIM, SEMA3B, NRP1, ARHGEF1, CBFA2T2, SLIT2, BAG5, AATK, RAPGEF2, SEMA3E, KIAA0319 |
1353 | GO:0051146 | 0.00 | 1.76 | 26.23 | 39 | 111 | striated muscle cell differentiation | AGTR2, BMP4, CACNB4, CASQ1, CASQ2, CAV3, CCNB1, CHUK, CXADR, FLT3LG, GATA4, GATA6, KAT2A, GPX1, NRG1, IGF1, IGF2, RBPJ, ITGB1, YBX1, PRKAR1A, RARA, RARB, RB1, RXRA, RYR1, SORT1, SGCB, SLC9A1, SRF, TSC1, WNT1, SORBS2, TNFSF14, DYRK1B, CTDP1, AKAP6, ATG5, GDF15 |
1354 | GO:0032944 | 0.01 | 1.76 | 18.14 | 27 | 77 | regulation of mononuclear cell proliferation | ANXA1, CD3E, CD4, CD6, CD28, CD86, CD59, CDKN1A, CHRNB2, CLC, EFNB1, IFNG, IGF1, IGF2, IL12B, IL13, IL18, IRF1, LMO1, PRKCQ, RAC2, SOS2, STAT5B, TNFSF4, TNFSF9, RIPK2, TNFSF18 |
1355 | GO:0048513 | 0.00 | 1.76 | 39.27 | 59 | 187 | animal organ development | AMELY, STS, BCL2L1, BMP3, BMP8B, CAPN5, CHAT, COL9A3, DNASE1L2, ECM1, EFNB1, EVPL, FANCF, FANCG, CENPI, GDF9, GPLD1, ICAM1, IDH1, ING2, KRT2, KRT9, OMD, PRKACG, PTPRN, S100A4, S100A7, SEMA3F, SPRR2A, SPRR2D, SPRR2E, SPRR2G, SPRR3, SRY, CLEC3B, TSG101, TSPY1, SEMA3B, FGF23, MADCAM1, NRIP1, PTCH2, AKR1C3, TRADD, SCEL, NRP2, EIF2B2, EIF2S2, CLDN1, LATS1, DYRK1B, ITGB1BP1, NRG2, MINPP1, TRAF4, ZNF516, SEMA3E, REC8, AKAP9 |
1356 | GO:0090317 | 0.04 | 1.76 | 12.76 | 19 | 54 | negative regulation of intracellular protein transport | ANGPT1, BARD1, CD36, GDI1, IL10, TONSL, PPM1B, RANGAP1, SFRP5, SP100, TRIP6, AKAP1, DYRK2, OGT, TNFSF14, ITGB1BP1, SLC9A3R1, LITAF, BAG4 |
1357 | GO:0001822 | 0.00 | 1.76 | 33.04 | 49 | 140 | kidney development | ACVR2B, AGTR1, AGTR2, ARG2, ASS1, BAX, CAT, CD44, CENPF, COL4A3, CTSH, DCN, ACE, EDNRA, FBN1, GPC3, HMGCS2, HOXC11, ILK, KCNJ1, KCNJ8, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, OVOL1, PCSK5, SERPINF1, PRKX, PSPN, RARA, RARB, SALL1, SDC4, SLC12A1, SLC34A1, SOX9, SOX11, TP73, TSC1, UPK3A, WFS1, WNT1, WNT11, RGN, SLIT2, BCL2L11, SPRY1 |
1358 | GO:0035108 | 0.03 | 1.76 | 13.43 | 20 | 57 | limb morphogenesis | ATRX, BAX, RUNX2, DLX5, EN1, GNAQ, HOXC10, HOXC11, HOXD12, IDUA, IHH, PCSK5, SOX9, SOX11, TULP3, ZNF141, FZD6, TP63, IFT140, BCL2L11 |
1359 | GO:0034111 | 0.03 | 1.75 | 13.47 | 20 | 57 | negative regulation of homotypic cell-cell adhesion | ABAT, ANXA1, BMP4, CBLB, CTLA4, IFNA2, IHH, IL2RA, IL10, IDO1, IRF1, PRKAR1A, PTPN6, XCL1, SFTPD, TNFSF4, SCGB1A1, PDE5A, TNFSF18, SOCS6 |
1360 | GO:0030509 | 0.03 | 1.75 | 14.15 | 21 | 60 | BMP signaling pathway | ABL1, ACVR2B, XIAP, BMP1, BMP3, BMP8B, BMPR1A, RUNX2, DLX5, FBN1, GDF9, SMAD1, SMAD6, SMAD7, SMAD9, RYR2, WNT1, USP9X, USP9Y, CHRD, ZFYVE16 |
1361 | GO:0051960 | 0.00 | 1.75 | 89.57 | 131 | 380 | regulation of nervous system development | ABL1, ABL2, APP, ARF1, ARHGAP4, ARNTL, ASCL1, ASCL2, ADGRB2, BMP4, BMPR1A, BMPR2, TSPO, CACNA1A, CDC20, CHN1, CHRNB2, CNR1, CREB1, CRX, CTNNA1, CX3CR1, BRINP1, DCC, DDX6, DNM2, DNMT3B, DPYSL3, DRD3, LPAR1, EFNA1, EFNA5, EIF4E, EMX1, CTTN, EPHB1, EPHB2, EPHB3, ETV5, F2, PTK2B, EFEMP1, FGFR3, FYN, FZD2, GDI1, GFAP, GHSR, GOLGA4, RAPGEF1, GRID2, FOXA2, IGF1, ILK, ISL1, ITGB1, KIT, LIMK1, CAPRIN1, NRCAM, NTF4, NTRK2, NTRK3, OPA1, OXTR, P2RY2, PALM, PCM1, PCP4, SERPINF1, PRKACB, PRKCI, PRKD1, PTK2, PTN, RAC1, RAC3, RAP1GAP, RAP2A, REST, RHEB, RNF6, SALL1, CX3CL1, SEMA3F, SGK1, SIX3, SMARCD3, SNAP25, SOX3, SOX9, SOX10, SOX11, SPOCK1, SRF, STAT3, SYT1, SYT4, CNTN2, DYNLT1, TNR, TP73, TPBG, TTC3, TULP3, VIM, XRCC2, XRCC5, RNF112, SEMA3B, RND2, SOX14, CHRD, NUMB, NRP1, PHOX2B, ARHGEF1, CBFA2T2, ARHGEF2, KLF4, SLIT2, NRXN3, NRXN1, BAG5, AATK, RAPGEF2, RIMS2, SEMA3E, CUL7, KIAA0319, OLIG2 |
1362 | GO:0045861 | 0.00 | 1.75 | 54.36 | 80 | 230 | negative regulation of proteolysis | BIRC3, XIAP, BIRC5, APLP2, APP, BST2, BUB1B, C3, CCNB1, CD44, CD59, CDC20, CDC27, CENPF, COL4A3, COL6A3, CSNK2A1, CSNK2A2, CST6, DPEP1, DUSP1, ECM1, SERPINB1, F2, GAS1, GPC3, GPX1, HGF, HRG, DNAJB2, IFI16, IL10, INS, ITIH1, ITIH4, KNG1, SERPINE1, SERPINA5, SERPINF1, SERPINA4, SERPINB5, SERPINB9, SERPINB13, SERPINI2, PZP, RAF1, RAG1, RENBP, RPS6KA1, SERPINB4, SLPI, SNCA, SPINK1, SPOCK1, TRIM21, SERPINA7, TRAF2, TTK, NR1H2, VIL1, VTN, WNT1, ZNF207, PICALM, CDC23, SERPINB7, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, CDC16, USP14, ZW10, KLF4, PSMF1, TMEM59, BAG5, HDAC6 |
1363 | GO:0000086 | 0.01 | 1.75 | 25.01 | 37 | 106 | G2/M transition of mitotic cell cycle | BIRC5, BACH1, CCNB1, CDC25A, CDC25C, CDK2, CDKN1A, CENPF, CHEK1, CSNK1D, DYNC1H1, DNM2, EP300, FOXO4, PPP1R12A, PPP1R12B, NUMA1, PCM1, PPP2R1A, PPP2R2A, PRKAR2B, PRKCQ, SKP1, TPD52L1, TUBA4A, TUBG1, UBB, TUBA1A, CUL1, PPM1D, SSNA1, DYNLL1, LATS1, CCNB2, CEP135, CKAP5, AKAP9 |
1364 | GO:0045935 | 0.00 | 1.75 | 192.76 | 276 | 821 | positive regulation of nucleobase-containing compound metabolic process | ACVRL1, AGTR2, ALK, ANXA3, APP, PHOX2A, ARNTL, ASCL1, ATF4, RERE, ATR, ATRX, BACH1, BAX, BCL3, BMP3, BMP4, BMPR1A, BMPR2, BRCA2, BRDT, ZFP36L2, KLF5, BTK, CAMK2A, CAT, RUNX2, CCNB1, CCNC, CCNE1, CCNT2, CD3D, CD28, CD86, TNFSF8, CDH1, CDK2, CDK8, CDX2, CEBPE, CHEK1, CHUK, CLU, COL1A1, CREB1, CRX, CTH, DCN, DDX5, DKC1, DLX5, DNM2, DRD3, ARID3A, EBF1, EDA, S1PR1, EGR2, ELK1, EN1, EP300, EPHA5, ERCC3, ERCC6, ESRRG, ETS1, ETV4, ETV5, ETV6, EVX1, EZH1, F2R, PTK2B, FGF4, FGF7, FSHB, NR5A2, GALR1, GATA4, GATA6, KAT2A, HCLS1, HEXB, HGF, NRG1, HHEX, HMGN1, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HOXC11, HOXD8, HOXD9, HOXD10, HSF4, ICAM1, IFI16, IFNA2, IFNG, IGF1R, IGF2, RBPJ, IHH, IL1A, IL10, ILK, ING2, INSIG1, IRAK1, IRAK2, IRF1, IRF5, ISL1, JUN, JUND, KIT, LMO1, LTF, SMAD1, SMAD3, SMAD7, SMAD9, MEOX2, KITLG, MGMT, CIITA, AFF1, FOXO4, PPP1R12A, YBX1, NVL, OTX1, OTX2, SERPINE1, PAX3, PAX9, PCK1, PCNA, PGR, PHF2, PRKCI, PRKD1, PRKCQ, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PTEN, RAC1, RAD21, RAD51, RAN, RARA, RARB, RB1, UPF1, REST, RFX3, RFXAP, RLF, RNF6, RPS3, RPS6KA1, RXRA, RXRG, S100A8, S100A9, S100A12, SALL1, SETMAR, SHC1, SIX3, SLC9A1, SMARCA1, SMARCA2, SMARCA4, SMARCD3, SNAI1, SNRNP70, SOX9, SOX10, SOX11, SP1, SP100, SREBF1, SRF, SRY, TRIM21, SSRP1, STAT4, STAT5B, STAT6, SUPV3L1, TAF7, TAL1, TBL1X, TBP, HNF1A, NR2F2, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C2, TRAF1, TRAF2, TNFSF4, UBB, UBE3A, UNG, NR1H2, USF1, WNT1, WNT11, YY1, ZIC1, CNBP, ZSCAN21, TRIM25, ZNF148, ZBTB17, ZXDA, FZD5, ARHGEF5, FOSL1, FGF23, NRIP1, PICALM, FZD4, FZD7, FZD8, OGT, IKBKG, STK16, KLF7, TP63, TRADD, RIPK1, RIPK2, BUD31, PHOX2B, RPS6KA4, TNFSF18, RNF8, BAZ1B, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, AURKB, VAPB, CCPG1, ITGB1BP1, KLF4, HMGN3, HAND1, EIF2AK3, FHL5, ONECUT2, GTPBP1, CLOCK, RNF14, ZNF516, ARHGEF11, ZEB2, RNF10, NR1I3, NR1H4, NR1D2, NR2E3, RAD50, RNF41 |
1365 | GO:0008637 | 0.03 | 1.75 | 14.18 | 21 | 60 | apoptotic mitochondrial changes | ATP2A1, BAD, BAX, BCL2A1, BCL2L1, BNIP3L, CAMK2A, CLU, EYA2, GPX1, HGF, IGF1, JUN, OPA1, PPP2CB, SOD2, YWHAZ, DYNLL1, HRK, TNFSF10, BCL2L11 |
1366 | GO:0055088 | 0.03 | 1.75 | 14.18 | 21 | 60 | lipid homeostasis | ABCA1, ABCA2, ACADM, ACADS, CAV3, NR5A2, G6PC, INS, IVD, LCAT, LIPC, PRKAA1, ACSM3, NR1H2, USF1, ACOX3, DGAT1, LIPG, NR1H4, NR1D2, COL4A3BP |
1367 | GO:0098661 | 0.03 | 1.75 | 14.18 | 21 | 60 | inorganic anion transmembrane transport | CLCA1, CLCN3, CLCN7, CLCNKA, CLCNKB, GABRA4, GABRA5, GABRE, GABRG1, GABRR1, GABRR2, GLRA1, FXYD3, PTAFR, SLC4A1, SLC12A1, SLC12A2, SLC13A1, SLC34A1, SLC20A1, SLC12A6 |
1368 | GO:0008203 | 0.03 | 1.74 | 14.89 | 22 | 63 | cholesterol metabolic process | ABCA1, APLP2, APP, CAT, CYP11B1, DHCR7, CYB5R3, FDFT1, FDPS, HMGCR, HMGCS2, INSIG1, LCAT, LIPC, LIPE, PRKAA1, RXRA, SREBF1, TNFSF4, CNBP, SNX17, NR1H4 |
1369 | GO:0046916 | 0.03 | 1.74 | 14.89 | 22 | 63 | cellular transition metal ion homeostasis | ABCB7, ALAS2, APLP2, APP, ARF1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, FTL, HPX, LTF, NUBP1, S100A8, S100A9, SCO1, SLC30A2, AP3D1, ATP6V0D1, ATP6V1G1, ABCB6 |
1370 | GO:0072329 | 0.03 | 1.74 | 14.89 | 22 | 63 | monocarboxylic acid catabolic process | ABAT, ACACB, ACADM, ACADS, ABCD1, CNR1, CPT1B, CPT2, CRAT, ECH1, FAAH, GOT2, IDUA, IVD, LIPE, PEX7, PEX13, ABCD3, SORD, ACOX3, ALDH4A1, XYLB |
1371 | GO:0048869 | 0.00 | 1.74 | 179.82 | 257 | 809 | cellular developmental process | ABCA1, ACVR2B, ACVRL1, ADAR, AGTR1, NR0B1, ALAS2, ALDOC, ALOX15B, APAF1, PHOX2A, ARNT, ASTN1, BCHE, BCL3, BLK, BOK, BRDT, ZFP36L2, BYSL, CAPN5, DAGLA, CAT, CBR1, CCNE1, CD3D, CD3E, CD4, CD8A, CD28, CD86, TNFSF8, CD36, CD63, CDH15, CDX2, CEBPE, CENPF, CHD2, CHUK, TBCB, TPP1, CNN3, COL15A1, CPS1, CR2, CRP, VCAN, CSPG4, CSRP2, CTGF, CTH, CTLA4, CYLC1, CYLC2, DAZ1, ACE, DDX5, DHCR7, DMBT1, DNMT1, TYMP, EDA, S1PR1, EGR3, ELAVL3, ELK1, EML1, EMP2, EMX2, ERCC3, ERF, ETS1, ETV3, ETV6, EVPL, EXT2, FABP7, FLOT2, FLT1, FLT3, FLT3LG, FSHB, FSHR, NR5A2, GAS1, KAT2A, GPC3, GNAS, GPLD1, HIST1H1T, HCLS1, HHEX, HIP1, HLF, HMBS, HMGCR, NR4A1, HMX2, HNRNPC, HTR2C, IAPP, IFI16, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGF2, IGFBP3, IL10, IL12B, IL13, IL18, INSIG1, IRF1, ITGAM, JARID2, KCNA1, KRT2, LAMA3, LLGL2, LTA4H, SMAD1, SMAD6, MAL, MGMT, FOXO4, YBX1, NUMA1, ODF1, OMP, PA2G4, PCNA, PENK, PEX7, PEX13, PRKX, PSAP, PTPRJ, PTPRR, PURA, RAB27A, RAG1, RAG2, RBM4, RFNG, RPL22, RPS3A, RPS11, SORT1, S100A7, SATB1, SFRP5, SHB, SIM2, SLC2A4, SLC8A3, SLC9A1, SMARCA1, SMARCE1, SP1, SPIB, SPRR2A, SPRR2D, SPRR2E, SPRR2G, SPRR3, SRD5A1, SRPK2, SRY, STAT5B, STAT6, SULT1E1, TACC1, ADAM17, NR2F1, NR2F2, KLF10, TNNI3, TOP2A, TPD52, NR2C2, TSC1, TSG101, TSPY1, TULP3, TNFSF4, UPK1B, UCP1, NR1H2, UPK2, KDM6A, VTN, YY1, ZIC1, ZNF3, ZNF16, ZNF217, KCNAB1, AIMP2, SLC7A5, MADCAM1, HIST1H4I, FZD8, FZD9, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, TAGLN2, CUL4A, FKBP6, OGT, PIR, AP3B1, RGS20, AKR1C3, CHRD, RIPK1, TNFSF14, TNFSF9, RIPK2, DLK1, SCEL, PEX11A, SAP30, INPP4B, AP1M1, AP3D1, TNFSF18, SOCS3, DYRK1B, DDX21, PDLIM7, BCL7B, GPR55, COPS2, GTF3C5, HAND1, CXCL14, SOX13, ZNF516, SPOCK2, SPATA2, ZBTB24, GAB2, NR1I3, NR1D2, HDAC6, ARL4A, DHRS9, RNF41, DHRS2 |
1372 | GO:0002064 | 0.00 | 1.74 | 27.84 | 41 | 118 | epithelial cell development | ARNTL, ATP2B2, ATRX, BAD, PRDM1, BMP4, KLF5, CDK6, CLDN3, CRYGB, DNASE1L2, EPHA2, FGFR3, B4GALT1, GPX1, RAPGEF1, ONECUT1, ICAM1, IHH, PROC, PTPRS, RAC1, RARA, RARB, RHEB, SALL1, SOX9, ST14, STC1, TNFRSF1A, CLRN1, VIM, VEZF1, FZD7, TP63, SLC9A3R1, ONECUT2, SLC4A7, CLOCK, RAPGEF2, AKAP9 |
1373 | GO:0043901 | 0.01 | 1.74 | 21.03 | 31 | 89 | negative regulation of multi-organism process | ADAR, ARHGDIB, PRDM1, BST2, CD36, FBLN1, IFI16, IFIT1, IFNA2, IFNG, IGF1, IL2RA, IL10, IL12B, ISG20, ITGAV, JUN, LTF, OAS3, OVGP1, PCBP2, PPM1B, REST, SEC14L1, SLPI, SP100, SRPK2, TRIM21, TRIM25, TPST2, VAPB |
1374 | GO:0044281 | 0.00 | 1.74 | 231.22 | 327 | 999 | small molecule metabolic process | ABCA1, ABCB7, ACADS, ACO2, ACY1, ADRA1B, ADSS, AK1, AK2, ALAD, ALAS2, ALB, ABCD1, AMPD1, AMPD2, ANGPT1, APLP2, APP, APRT, ARF1, ARG1, ARG2, ARL2, ARNT, ARSA, STS, ARSD, ARSE, ARSF, ATP1A2, ATP2B2, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1B2, ATP6V0A1, AUH, AVPR2, BAD, BCHE, BCKDHA, BLVRA, BMP1, BSG, TSPO, C3, DAGLA, CA4, CACNA1A, CACNB4, CALM3, CAT, CD36, ENTPD2, CD44, CDA, CHRM3, CKM, CNP, COX6A1, COX6B1, COX7C, COX8A, COX15, CPOX, CPT1B, CPT2, CRAT, CRH, CTGF, CTNS, CYC1, CYP2A6, CYP2A13, CYP2F1, DBH, DBI, DBT, DLG2, DLG3, SARDH, DNM2, DNMT1, DNMT3B, DPEP1, DRD3, DRD5, TYMP, ECH1, LPAR1, EDNRA, EPRS, EXT2, EXTL1, EXTL3, FAAH, FABP2, FABP7, FAU, FSHR, NR5A2, FUT6, FUT8, FZD2, GAA, GALC, GALE, GALK2, GALR1, GALNS, GCGR, B4GALT1, GHRHR, GK2, GLDC, GM2A, GNAS, GNG3, GNG10, GPLD1, FFAR1, GPX1, GSTZ1, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GYS2, GUCY2D, HARS, HBA2, HEXA, HEXB, HMBS, FOXA2, ONECUT1, HNMT, HPRT1, HSD11B1, HTR2C, IDH1, IDH3A, IDS, IDUA, IGF1, IGF2, IGFBP3, IMPDH1, IMPDH2, INPP1, INPPL1, ITPR1, IVD, KCNC2, KCNJ11, KCNS3, LIPE, MAN2B1, NUBP1, NTHL1, NTRK2, NUP98, OMD, OGDH, P2RX7, P2RY11, P4HA1, PALM, PAM, PDE4B, PDE8A, PEPD, PEX7, PEX13, PFAS, PHKA2, PHKB, PHKG1, PIK3C2B, PI4KA, PIP4K2A, PPP2R5D, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKD1, PRPSAP1, PSAP, PTEN, PTGDR, PYGB, PYGM, QDPR, RAF1, RAN, RCVRN, RENBP, RHAG, RPE, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, RRM1, RRM2, SDHA, SDHB, SDHC, SDHD, SLC2A4, SLC2A5, SLC4A1, SLC6A6, SLC7A4, SLC9A1, SLC10A1, SLC34A1, SLCO1A2, SLC22A1, SLC22A3, SLC22A2, SLC22A5, SMARCD3, SMS, SNAP25, SP1, STAT3, SULT1E1, SULT1A3, SULT1C2, SULT2B1, SUOX, SYT5, TAT, TAZ, TBL1X, TNFRSF1A, TPMT, TNFSF4, TYMS, TYR, UBB, UCP1, UGT2B7, UNG, UPP1, UQCRC1, UQCRC2, UQCRH, USF1, VIP, VIPR2, WFS1, AIMP2, NUP214, AAAS, SLC7A5, ACOX3, DYRK2, PIK3R3, DDO, AGPS, PDE5A, DGAT1, B4GALT4, B4GALT3, PEX11A, SUCLG1, DPM2, INPP4B, CES2, SYNJ1, MBD4, MGAM, P4HA2, RPL14, PAPSS1, VAPB, B4GALT6, RPL23, LIPG, CHST3, AKAP6, TBPL1, TP53I3, MINPP1, GABBR2, AKAP12, GUCA1C, NUP155, HS2ST1, NUP93, EIF4A3, SNX17, PTDSS1, SPOCK2, EPM2AIP1, XYLB, HS3ST3B1, HS3ST1, GNE, ABCC5, COL4A3BP, SLC25A15 |
1375 | GO:0048585 | 0.03 | 1.74 | 14.86 | 22 | 65 | negative regulation of response to stimulus | ANGPT1, ANXA1, BST2, CD59, CDK6, CRH, FOXA2, IFI16, IFNA2, IGF2, IL13RA2, SERPINB9, RPS3, SERPINB4, XCL1, STAT6, TNFSF4, OGT, TP63, TNFSF18, USP14, IL27RA |
1376 | GO:0060284 | 0.00 | 1.73 | 102.05 | 148 | 433 | regulation of cell development | ABL1, ABL2, APP, ARF1, ARHGAP4, ASCL1, ASCL2, BAX, BMP4, BMPR1A, BMPR2, TSPO, CACNA1A, CAV3, CDC20, CHN1, CHRNB2, CNR1, COL1A1, CREB1, CRX, CTNNA1, CX3CR1, BRINP1, DCC, DDX6, DNM2, DNMT3B, DPYSL3, DRD3, LPAR1, EFNA1, EFNA5, EIF4E, ELAVL1, EMX1, CTTN, EPHB3, ETV5, F2, PTK2B, FBLN1, EFEMP1, FGA, FGFR3, FYN, GDI1, GFAP, B4GALT1, GOLGA4, RAPGEF1, GRID2, HGF, NRG1, FOXA2, IFNG, IGF1, ILK, INS, ISL1, ITGB1, KIT, LIMK1, CAPRIN1, SMAD3, SMAD7, CNOT2, NRCAM, NTF4, NTRK2, NTRK3, OPA1, P2RY2, PALM, PCM1, PCP4, SERPINF1, PPP2R1A, PRKCI, PRKD1, PROC, PTEN, PTK2, PTN, RAC1, RAC3, RAP1GAP, RAP2A, RARA, RARB, REST, RNF6, RPS19, SALL1, CX3CL1, SEMA3F, SGK1, SIX3, SMARCD3, SNAI1, SNAP25, SOX3, SOX9, SOX10, SOX11, SPOCK1, SRF, STAT3, SYT1, SYT4, TAL1, CNTN2, DYNLT1, TNFRSF1A, TNR, TP73, TTC3, VIM, TRPV1, XRCC2, XRCC5, RNF112, SEMA3B, RND2, SOX14, NUMB, PDE5A, NRP1, ARHGEF7, PHOX2B, ARHGEF1, CBFA2T2, CTDP1, ARHGEF2, ITGB1BP1, KLF4, SLIT2, AKAP6, BAG5, AATK, RAPGEF2, RIMS2, SEMA3E, CUL7, KIAA0319, RNF10, ARPC2, OLIG2 |
1377 | GO:0032844 | 0.01 | 1.73 | 25.15 | 37 | 108 | regulation of homeostatic process | ABAT, ANXA1, ARNT, ATP6AP1, ATR, ATRX, BGLAP, CD36, CDK6, CNR1, CSF1R, DKC1, TSC22D3, S1PR1, ERCC4, ETS1, FSHB, UBE2K, HNRNPC, IAPP, IL2RA, LMO1, KITLG, PDK4, PRKAA1, PRKCQ, SLC22A5, SMARCA4, STAT5B, ADAM17, TAL1, NR1H2, XRCC5, ZNF16, AURKB, NR1D2, RAD50 |
1378 | GO:0016043 | 0.00 | 1.73 | 86.67 | 126 | 404 | cellular component organization | ACACB, ACADS, ADAR, ALAD, ANXA6, BIRC3, APLP2, ARG1, ASL, ATP6V0A1, BCL3, CAT, CD3E, CD3G, ENTPD2, CD151, CDH6, CDH7, CDH8, CDH9, CDH10, CDH12, CDH15, CHRNB4, CLCN6, CLNS1A, COMP, COX15, VCAN, CTH, EPRS, FBLN2, B4GALT1, GJA4, GLRA1, HBA2, HBE1, UBE2K, HMGCR, ICAM2, ICAM4, IL1RAP, IMPDH2, EIF3E, IRAK1, ITGAD, ITGAM, KCNA1, KCNA3, KCNA4, KCNC2, KCND2, KCND3, KCNJ2, KCNS2, KCNS3, KPNA3, IPO5, KRT5, LAMA4, LIM2, LIPC, LTBP2, SMAD1, MATN3, MFAP3, OAT, P2RX1, P2RX3, P2RX4, P4HA1, SERPINB5, PLN, PPIB, PPP2R1B, PTPRS, PVR, RAB3B, RRM1, RRM2, RSU1, RXRG, SCO1, SRSF1, SRSF5, SFSWAP, SH3BGR, SHMT1, SHMT2, SLC34A1, SLC22A1, SNCB, SNRPC, SNRPE, TRIM21, TP73, TRAF1, TRAF2, TRIP6, USP4, VAV1, VBP1, ZNF148, CLPP, PRPF18, EIF3G, SRSF9, DGAT1, TRADD, RIPK1, BSN, CLDN12, CLDN6, CLDN1, PRPF3, SCAF11, REPS2, ZFYVE9, LIPG, DDX23, ADAMTS3, ADAMTS2, PDE4DIP, SDC3, ADAMTSL2, SPOCK2 |
1379 | GO:0071705 | 0.00 | 1.73 | 98.70 | 143 | 420 | nitrogen compound transport | ABCA1, ACVR2B, ANXA1, ANXA5, AQP6, ARG1, ARL2, ARNTL, ATP1A2, BAD, BCL3, BLK, CACNA1A, CACNB4, CHRM3, CRHBP, CTNS, EDA, EDNRA, EFNA5, EIF4E, EIF5A, EPHA5, FGA, GCG, GHRHR, GHSR, GIF, GJB1, GLE1, GLUD1, GNAS, GPLD1, FFAR1, HHEX, HMGCR, FOXA2, HTR2C, IFNG, IL1RN, IL10, IL12B, IL18, INS, ISL1, ITPR1, KCNC2, KCNJ10, KCNJ11, KCNS3, KISS1, NTRK2, NTSR1, NUP98, OAZ1, OAZ2, OXCT1, P2RX7, PRDX1, PPM1B, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRKCQ, PTPRN, PTPRN2, RAB1A, RAF1, RAN, RANBP2, UPF1, REST, RFX3, RHAG, RHCE, RHD, S100A8, S100A9, SEC14L1, SRSF1, SRSF5, SRSF7, SLC1A6, SLC6A6, SLC6A7, SLC6A13, SLC7A1, SLC7A4, SLC12A2, SLC15A1, SNAP25, SREBF1, STXBP3, SYT1, SYT5, TAF7, SERPINA7, HNF1A, TRIP6, TRPC4, TRPM2, TSC1, UPK3A, VIP, TRPV1, NUP214, AAAS, SLC7A5, SLC14A2, KHSRP, SLC25A12, VAMP8, SRSF9, RIPK1, TNFSF14, ARHGEF7, SLC5A6, SYT7, SLC6A5, HMGN3, SLC9A3R1, NRXN1, EIF2AK3, LITAF, CLOCK, NUP155, NUP93, RIMS2, EIF4A3, CKAP5, TOMM20, ZC3H11A, SMG7, RBM8A, NR1H4, COL4A3BP, SLC25A13, SLC25A15, SLC35B1 |
1380 | GO:0009896 | 0.00 | 1.73 | 54.83 | 80 | 232 | positive regulation of catabolic process | ADRA1B, APOH, ARNT, BAD, BARD1, BAX, BNIP3L, ZFP36L2, CAV3, CBLB, CCNB1, CDC20, CDC27, CLU, CSNK1D, CSNK2A1, DCN, PTK2B, GPC3, GPLD1, DNAJB2, IFNG, IGF1, INS, KDR, SMAD7, ATXN3, OAZ1, OAZ2, P2RX7, PIP4K2A, PRKAA1, PRKCE, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, RB1, UPF1, SKP1, SUMO3, SNCA, SOX9, TRIM21, SUPV3L1, TNFRSF1B, UBB, SUMO1, UVRAG, VIP, CUL3, CUL1, CDC23, CDC16, RGN, ATG5, PSMF1, TMEM59, SEC22B, GTPBP1, RNF14, DLGAP5, RNF40, PSME3, PSMD14 |
1381 | GO:0002252 | 0.00 | 1.73 | 78.48 | 114 | 334 | immune effector process | ABL1, ACTB, ADAR, ANGPT1, ANXA3, ANXA5, BIRC3, ARF1, BCL3, BCR, BNIP3L, BST2, BTK, C7, CD3G, CD4, CD8A, CD59, AP1S1, AP2S1, CLC, CLU, COX8A, CR2, CRP, CTSH, CX3CR1, CXADR, DBH, ACE, DMBT1, EMP2, PTK2B, FCN2, FGF7, FYN, GABRA5, GRB2, CFHR1, ICAM1, IFI16, IFIT1, IFIT3, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGF2, IL2RA, IL10, INS, IRF1, IRF5, ISG20, ITPR1, KCNJ8, KCNQ1, KIT, LIMK1, NTHL1, OAS3, PRDX1, PCBP2, PDK4, PEX13, CFP, SERPINB9, PPM1B, PRKCE, PTK2, PTPN6, RAB27A, RAC1, S100A13, SERPINB4, SCN1A, SEC14L1, SNRPD1, STAT2, STXBP3, ADAM17, TSC1, TYROBP, VTN, LAT2, TRIM25, ZNF189, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, STX11, AP1M1, HIST1H3F, TNFSF18, RNF8, EXO1, IL27RA, CHST3, ATG5, NUP93, PHYHIP, TRIL, FGFBP1, AP1M2, ABCC9, ARPC5, ARPC1B, ACTR2, ARPC2, WASF2 |
1382 | GO:0023057 | 0.04 | 1.73 | 13.56 | 20 | 59 | negative regulation of signaling | ANXA5, ARF1, BCHE, CRH, DRD5, PTK2B, GHSR, GLRA1, GNAI1, GRIA1, INHA, KCNJ11, PTGS1, REST, SREBF1, SRF, TNR, FGF23, DGKI, PICK1 |
1383 | GO:0010976 | 0.02 | 1.73 | 18.39 | 27 | 78 | positive regulation of neuron projection development | ABL2, ARF1, BMP4, CNR1, DPYSL3, LPAR1, PTK2B, FYN, RAPGEF1, HGF, ITGB1, CAPRIN1, OPA1, P2RY2, PALM, PCP4, SERPINF1, PRKCI, PRKD1, PTN, SGK1, SYT1, SYT4, CBFA2T2, RAPGEF2, RIMS2, CUL7 |
1384 | GO:0010033 | 0.01 | 1.72 | 22.74 | 34 | 113 | response to organic substance | ADH5, ALB, AMPD1, APOH, ATP5G3, ATRX, BCR, DAGLA, CASQ1, CHAT, CNP, COL6A2, F2R, GOT2, FFAR1, GYS2, DNAJB2, HSPA4, HSPA6, HSPB2, IDO1, NTSR1, PCNA, PTGER1, RFC3, S100A7, S100A8, SLPI, RNF103, FZD5, MANF, SLC10A3, USP14, GPR55 |
1385 | GO:0061061 | 0.00 | 1.72 | 27.31 | 40 | 117 | muscle structure development | ABL1, AGTR2, CACNB4, CASQ2, CDH15, CHUK, CSRP2, CTH, CTNNA1, FLOT2, FLT3LG, KAT2A, HSPB2, IGF2, IGFBP3, IL18, ILK, ITGB1, YBX1, NTN3, PRKAR1A, RARA, RARB, RBM4, REST, SORT1, SLC9A1, SMARCA2, SMARCD3, SOX9, SRF, NR2C2, TSC1, WNT1, SORBS2, TNFSF14, DYRK1B, ATG5, GDF15, CXCL14 |
1386 | GO:0050728 | 0.05 | 1.72 | 12.27 | 18 | 52 | negative regulation of inflammatory response | BCR, CX3CR1, ETS1, GHSR, IL2RA, INS, ISL1, SMAD3, SERPINF1, PROC, PTGIS, RPS19, TNFRSF1A, TNFRSF1B, TYRO3, SOCS3, KLF4, SLIT2 |
1387 | GO:0090596 | 0.03 | 1.72 | 14.32 | 21 | 61 | sensory organ morphogenesis | ATP2B2, BCR, COL11A1, DLX5, EPHB2, FGF3, FZD2, HMX2, INSIG1, KRT13, OTX1, RAC1, RPL38, SALL1, CLRN1, WNT1, ZIC1, FZD6, HESX1, NRP1, SLC9A3R1 |
1388 | GO:0031324 | 0.00 | 1.72 | 89.76 | 130 | 396 | negative regulation of cellular metabolic process | ABL1, ANGPT1, BIRC3, XIAP, APLP2, APP, BAX, BST2, C3, CALM3, CAV3, CCNC, CD44, CD59, CDKN1A, CHAD, COL4A3, COL6A3, COMT, CRYBA1, CST6, DCN, DLG2, DLG3, DPEP1, DUSP5, ECM1, SERPINB1, F2, FBLN1, FYN, GAS1, GPC3, GNAQ, GP1BA, GPX1, RAPGEF1, HMGCR, HRG, DNAJB2, HSPB1, IGF1, IGFBP3, ILK, ITGAV, ITIH1, ITIH4, KNG1, LIMK1, SMAD6, NTRK3, P2RX7, SERPINE1, SERPINA5, PCP4, SERPINF1, SERPINA4, SERPINB5, SERPINB9, SERPINB13, SERPINI2, PPP2R1A, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRPSAP1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTPN6, PTPRJ, PTPRR, PZP, RAF1, RAG1, RANBP2, RENBP, RPS6KA1, SERPINB4, SLPI, SPINK1, SPOCK1, SERPINA7, TRAF2, USP4, VIL1, VTN, AKAP1, PICALM, OGT, DYNLL1, SERPINB7, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, SOCS3, LATS1, ITGB1BP1, SOCS6, SLIT2, SLC9A3R1, ATG5, BAG4, RANBP9, TRAP1, FARP1, PSME3, PSMD14, CTDSPL, SPRY1 |
1389 | GO:0030218 | 0.05 | 1.72 | 12.29 | 18 | 52 | erythrocyte differentiation | ADAR, ADD1, ALAS2, ARNT, BMP4, CDK6, ETS1, HCLS1, INHA, KIT, RB1, RHAG, RPS19, SP1, SRF, STAT5B, TAL1, ZNF16 |
1390 | GO:0009144 | 0.01 | 1.72 | 26.71 | 39 | 113 | purine nucleoside triphosphate metabolic process | AK1, AK2, ALDOC, AMPD2, ARNT, ATP1A2, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1B2, ATP6V0A1, BAD, TSPO, COX8A, COX15, CTNS, ENO2, GAPDH, IGF1, INS, LDHC, OGDH, P2RX7, PGAM1, PPP2R5D, PRKAA1, PRKAG1, SDHC, SNCA, STAT3, TAZ, UQCRC1, UQCRC2, UQCRH, OGT, SLC25A13 |
1391 | GO:0000723 | 0.04 | 1.71 | 13.67 | 20 | 58 | telomere maintenance | ATR, ATRX, DKC1, ERCC4, HNRNPC, PRKCQ, RAD51D, UPF1, SP100, XRCC5, HIST1H4I, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, AURKB, DCLRE1A, RAD50 |
1392 | GO:0001843 | 0.04 | 1.71 | 13.00 | 19 | 55 | neural tube closure | APAF1, BBS4, BMP4, FZD2, KAT2A, OPA1, PAX3, PRKACB, RALA, RARA, SALL1, SDC4, STIL, ST14, TSC1, TULP3, KDM6A, FZD6, ZEB2 |
1393 | GO:0035295 | 0.00 | 1.71 | 60.71 | 88 | 259 | tube development | ACVRL1, AGTR2, APAF1, ARG1, ARG2, BAX, BBS4, BMPR1A, BMPR2, CAT, CAV3, CD44, CREB1, CRH, CSF1R, CTGF, CTSH, DHCR7, EDA, EDNRA, EPHA2, EIF4E, EN1, EP300, ETV4, ETV5, FGF3, FGF7, FZD2, KAT2A, B4GALT1, GPC3, HHEX, FOXA2, HSD11B1, IGF1, RBPJ, IL13, ILK, KDR, LTA4H, SMAD1, SMAD6, SMAD7, SMAD9, NUMA1, OPA1, PAX3, PGR, PRKACB, PRKX, PSPN, PTN, RALA, RARA, RYR2, SDC4, SFTPD, STIL, SIM2, SLC12A2, SOX9, SP1, SPARC, SREBF1, SRF, ST14, TSC1, TULP3, KDM6A, WNT1, AIMP2, FZD6, CHRD, NUMB, NRP1, ITGB1BP1, SLIT2, HAND1, ADAMTS2, TRAF4, ADAMTSL2, SEMA3E, IFT140, ZEB2, BCL2L11, ATP6AP2, SPRY1 |
1394 | GO:0030001 | 0.00 | 1.71 | 40.50 | 59 | 175 | metal ion transport | ATP1A3, ATP12A, ATP4A, ATP4B, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, CDK2, CNGA1, FTL, GIF, KCNA1, KCNA3, KCNA4, KCND2, KCND3, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNS3, REST, SCN1A, SCN2A, SCN7A, SCN8A, SCNN1A, SCNN1G, SCO1, SLC5A2, SLC9A2, SLC10A1, SLC12A1, SLC12A2, SLC13A1, SLC34A1, SLC20A1, SLC22A5, TSC1, PICALM, SLC5A6, SLC13A2, ATP6V0D1, KCNAB3, KCNK6, SLC4A7, ATP6V1G1, SLC12A6, HCN4, ABCC9, KCNMB2 |
1395 | GO:0006821 | 0.04 | 1.71 | 13.69 | 20 | 58 | chloride transport | TSPO, CLCA1, CLCN3, CLCN6, CLCN7, CLCNKA, CLCNKB, CLNS1A, GABRA4, GABRA5, GABRE, GABRG1, GABRR1, GABRR2, GLRA1, FXYD3, PTAFR, SLC4A1, SLC12A1, SLC12A6 |
1396 | GO:0048588 | 0.01 | 1.71 | 22.65 | 33 | 96 | developmental cell growth | ABL1, APP, ARHGAP4, BMPR2, DCC, DNM2, EFNA5, EMX1, CTTN, GDF9, GOLGA4, NRG1, ILK, ITGB1, LIMK1, NRCAM, NTRK3, RNF6, SEMA3F, SOX9, SRF, SYT1, SYT4, TNR, SEMA3B, RND2, USP9X, NRP2, NRP1, SLIT2, AATK, RIMS2, SEMA3E |
1397 | GO:0006897 | 0.00 | 1.71 | 35.04 | 51 | 150 | endocytosis | ABCA1, ABL1, ABL2, ACTB, ANXA1, ANXA3, ANXA11, APP, ARR3, BCL2L1, BLK, CD3G, CEBPE, CLCN3, CRP, FCN2, FGR, FYN, INPPL1, ITPR1, LIMK1, P2RX7, PRKCE, PRKD1, PTEN, PTK2, RAB1A, RAB4A, RAB5B, RARA, SORT1, SYP, ICAM5, TYRO3, UBE3A, NR1H2, VAV1, EEA1, RABEP1, TRIP10, ZFYVE9, RIN1, CLINT1, ZFYVE16, TOM1, ATP9A, ARPC5, ARPC1B, ACTR2, ARPC2, WASF2 |
1398 | GO:0043009 | 0.01 | 1.71 | 23.30 | 34 | 100 | chordate embryonic development | ALX3, APAF1, BBS4, BMP4, RUNX2, COL1A1, COL11A1, EPHA2, EN1, FZD2, GNAS, HOXC11, HOXD9, HOXD10, ISL1, OPA1, PCSK5, PRKACB, RALA, RARA, SALL1, SDC4, SOX11, TSC1, TULP3, WNT1, WNT11, FZD6, CHRD, DLK1, IFT140, EIF4A3, ATP6AP2, IRX5 |
1399 | GO:0090288 | 0.04 | 1.70 | 14.42 | 21 | 61 | negative regulation of cellular response to growth factor stimulus | ABL1, AGTR2, DCN, DNM2, FBN1, HHEX, ONECUT1, HRG, SMAD3, SMAD6, SMAD7, ADAM17, UBB, WNT1, CHRD, SLIT2, ZFYVE9, ONECUT2, ADAMTSL2, PDCD6, SPRY1 |
1400 | GO:1901292 | 0.04 | 1.70 | 14.42 | 21 | 61 | nucleoside phosphate catabolic process | ARNT, CAT, ENTPD2, CNP, GPX1, HPRT1, IGF1, INS, NTHL1, P2RX7, PDE4B, PDE8A, PGAM1, PRKAA1, PRKAG1, STAT3, UNG, UPP1, OGT, PDE5A, MBD4 |
1401 | GO:0051169 | 0.00 | 1.70 | 58.85 | 85 | 249 | nuclear transport | ADAR, AGTR2, ANGPT1, ARNTL, RERE, BARD1, BCL3, BMP4, BMPR1A, CBLB, CD36, CDH1, CDKN1A, CSE1L, EDA, EGR2, EIF4E, EIF5A, F2R, FYB, GLE1, GNAQ, HCLS1, HHEX, HSPA9, IFNG, IGF1, IL10, IL12B, IL18, JUN, KPNA1, KPNA2, KPNA3, KPNA4, IPO5, SMAD3, PPP1R12A, TONSL, NUP98, PRDX1, PPM1B, PRKCQ, RAN, RANBP2, RANGAP1, RBM4, UPF1, SET, SFRP5, SRSF1, SRSF5, SRSF7, SIX3, SLC9A1, SP100, STAT3, STYX, DYNLT1, TRIP6, TSC1, ZIC1, NUP214, AAAS, ANP32A, AKAP1, FZD7, DYRK2, RGS20, AKR1C3, SRSF9, TNFSF14, INPP4B, RPL23, SLC9A3R1, ZFYVE9, AKAP6, LITAF, NUP155, IPO13, NUP93, ZC3H11A, SMG7, RBM8A, NUTF2 |
1402 | GO:0009967 | 0.00 | 1.70 | 49.53 | 72 | 220 | positive regulation of signal transduction | ABAT, ACPP, ACVR2B, ACVRL1, ALOX15B, XIAP, ARHGAP4, ARHGAP6, ARNT, ARNTL, ASCL1, BMP1, BMP3, BMP8B, BMPR1A, BMPR2, CD63, CHN1, CHN2, COL1A1, CSNK1D, CSNK2A1, CYBA, DLX5, DRD3, EMP2, FZD2, GATA4, GATA6, GDF9, GHRHR, GHSR, GPC3, GRB7, HHEX, UBE2K, FOXA2, RBPJ, IHH, ING2, INHA, ITGA5, KCNN4, NTSR1, PTGIS, RFNG, SALL1, SH3BGR, SH3BGRL, SH3BP2, SHB, SMARCA4, STAT3, ADAM17, CNTN2, NR2C1, TTK, VTN, WNT1, CNTNAP1, BUD31, NRXN1, GRAP2, ADAMTS3, GDF15, RIMS2, FGFBP1, HDAC6, FRAT1, SH2D3C, SH2D3A, ATP6AP2 |
1403 | GO:0006029 | 0.03 | 1.70 | 15.13 | 22 | 64 | proteoglycan metabolic process | BMPR2, COL11A1, VCAN, CSPG4, DCN, EXT2, EXTL1, EXTL3, GPC4, GPC3, HEXA, HEXB, IDS, IDUA, IGF1, IHH, LIPC, SDC4, CHST3, SDC3, SPOCK2, HS3ST3B1 |
1404 | GO:0022603 | 0.00 | 1.70 | 31.67 | 46 | 136 | regulation of anatomical structure morphogenesis | ACVRL1, ANGPT2, ANXA3, APOH, KLK3, ADGRB2, C3, KRIT1, CD36, CDX2, CCR3, COL4A3, CTSH, CX3CR1, DCN, ECM1, EPHA2, EMP2, ETS1, F3, FLT1, FLT3LG, GATA4, GATA6, GTF2I, HHEX, HSPB1, IL1A, IL1RN, ITGA5, FOXO4, OPA1, OTX2, SERPINE1, PAX3, SERPINF1, PRKD1, PTGIS, CX3CL1, SFRP5, SP100, VEGFB, TNFSF14, KLF4, GDF15, PDCD6 |
1405 | GO:0051348 | 0.00 | 1.70 | 50.57 | 73 | 214 | negative regulation of transferase activity | ABL1, ADAR, BMP4, BUB1B, CAV3, CCNB1, CDC20, CDC27, CDKN1A, CENPF, CHAD, DCN, DUSP1, DUSP5, GNAQ, GP1BA, HHEX, HMGCR, FOXA2, HSPB1, IGF1R, ILK, LIMK1, SMAD7, PCP4, PPP2R1A, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRPSAP1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTPN6, PTPRJ, RANBP2, RB1, TAF7, NR2F2, TP73, TTK, UBB, ZNF207, CUL3, CDC23, CDC16, SOCS3, RGN, LATS1, ZW10, ITGB1BP1, SOCS6, PSMF1, BAG5, PSME3, PSMD14, SPRY1 |
1406 | GO:0002230 | 0.03 | 1.70 | 15.83 | 23 | 67 | positive regulation of defense response to virus by host | ANXA5, COX8A, FGF7, GABRA5, IL12B, KCNQ1, NTHL1, PDK4, PEX13, SCN1A, SNRPD1, STAT2, ZNF189, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H3F, CHST3, NUP93, PHYHIP, FGFBP1 |
1407 | GO:0048489 | 0.03 | 1.70 | 15.83 | 23 | 67 | synaptic vesicle transport | AMPH, ARF1, CACNA1A, CANX, DNM1, DNM2, P2RX7, PFN2, SEPT5, RAB5A, RAB27A, SNAP25, SNCA, SYN1, SYT1, SYT5, AP3B1, STX11, LIN7A, SYNJ1, AP3D1, SNAP29, RIMS2 |
1408 | GO:0002684 | 0.01 | 1.69 | 22.67 | 33 | 99 | positive regulation of immune system process | ARNT, ATP6AP1, AXL, BAD, PRDM1, CD5, CD6, CDKN1A, CHRNB2, CSF1R, DPP4, EFNB1, EGR3, ETS1, FLOT2, FLT3LG, GNAS, HCLS1, IGF1, IGF2, IHH, IL2RA, IL18, RAG1, RB1, TAL1, KLF10, ZNF16, OGT, AP3B1, TNFSF9, AP3D1, IL1RL1 |
1409 | GO:0007219 | 0.01 | 1.69 | 26.94 | 39 | 114 | Notch signaling pathway | ADAM10, APP, ASCL1, CCNC, CDH6, CDK6, CDK8, CREB1, EP300, FCER2, B4GALT1, GMDS, HHEX, FOXA2, ONECUT1, RBPJ, IL2RA, KIT, LLGL2, PLN, RFNG, RPS19, SKP1, SNAI1, SOX9, STAT3, ADAM17, TBL1X, UBB, WNT1, CUL1, SORBS2, TP63, NUMB, DLK1, ITGB1BP1, NR1H4, RBX1, RCAN2 |
1410 | GO:0019752 | 0.00 | 1.69 | 100.05 | 143 | 428 | carboxylic acid metabolic process | ACADS, ACY1, ADSS, ALB, ABCD1, ALDOC, ARG1, ARG2, ARNT, ATF4, AUH, BCKDHA, BSG, C3, DAGLA, CACNA1A, CKM, CNR1, COMT, CPT1B, CPT2, CRAT, CTNS, CYP2A6, CYP2A13, CYP2F1, DBT, SARDH, DNMT1, DNMT3B, DPEP1, ECH1, ENO2, EPRS, FAAH, FAU, NR5A2, GAPDH, GHSR, GLDC, GPX1, GSTZ1, HARS, HLCS, HNMT, IDUA, IGF1, INS, IVD, LIPE, OAZ1, OAZ2, P2RX7, P4HA1, PAM, PCK1, PEPD, PEX7, PEX13, PFAS, PGAM1, PPP2R5D, PRKAR2B, PRKCE, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, QDPR, RENBP, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, RXRA, SLC6A6, SLC7A4, SLC10A1, SLCO1A2, SLC22A5, SMS, SNCA, SORD, SREBF1, STAT3, SUOX, TAT, TNFRSF1A, TYMS, TYR, UGT2B7, AIMP2, SLC25A16, PDHX, SLC7A5, ACOX3, OGT, DDO, VNN2, SLC5A6, P4HA2, RPL14, RPL23, EIF2AK3, PSMF1, EIF4A3, PTDSS1, XYLB, GNE, SLC25A15, PSME3, PSMD14 |
1411 | GO:1903707 | 0.03 | 1.69 | 17.25 | 25 | 73 | negative regulation of hemopoiesis | ANXA1, BMP4, CDK6, CTLA4, PTK2B, FLT3, IFNA2, IHH, INHA, IRF1, LTF, RARA, STAT5B, TNFSF4, HIST1H4I, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, INPP4B, TNFSF18, GPR55 |
1412 | GO:1901360 | 0.02 | 1.69 | 17.08 | 25 | 80 | organic cyclic compound metabolic process | ABAT, BCHE, BLVRA, CHRNB2, CTRB1, CYP2F1, SARDH, GIF, GOT2, GRIN2A, GSTZ1, HLCS, HNMT, HPX, P4HA1, ABCD4, SHMT2, SLC34A1, SNCB, TACR3, TAT, VNN2, SLC5A6, P4HA2, SNCAIP |
1413 | GO:0019932 | 0.01 | 1.69 | 22.83 | 33 | 97 | second-messenger-mediated signaling | AGTR1, ATP1A2, BTK, CALM3, CASQ1, CASQ2, CD3E, CD4, CD8A, EPHA5, PTK2B, GHRHR, GNAI1, GNAS, HRC, KDR, NTRK2, P2RX3, P2RX4, P2RX5, P2RY11, PLN, PPP2R1A, RYR2, SELE, SELP, SOX9, LAT2, RGN, GSTO1, EIF2AK3, RAPGEF2, RIMS2 |
1414 | GO:0010648 | 0.04 | 1.68 | 15.17 | 22 | 66 | negative regulation of cell communication | ANXA5, ARF1, BCHE, TSPO, CRH, DRD5, PTK2B, GHSR, GLRA1, GNAI1, GRIA1, INHA, KCNJ11, PTGS1, REST, SREBF1, SRF, TNR, FGF23, DGKI, PICK1, FEZ2 |
1415 | GO:0006414 | 0.02 | 1.68 | 21.51 | 31 | 91 | translational elongation | EEF1B2, EIF5A, FAU, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, SRP9, TUFM, RPL14, RPL23, GTPBP1, EIF4A3 |
1416 | GO:0042278 | 0.00 | 1.68 | 40.41 | 58 | 171 | purine nucleoside metabolic process | ACACB, ACPP, ADSS, AHCY, AK1, AK2, ALDOC, AMPD2, APRT, ARNT, ATP1A2, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1B2, ATP6V0A1, BAD, TSPO, COX8A, COX15, CTNS, DLG2, DLG3, DNMT1, DNMT3B, ENO2, GAPDH, HMGCR, HPRT1, IGF1, IMPDH1, IMPDH2, INS, LDHC, OGDH, P2RX7, PGAM1, PPP2R5D, PRKAA1, PRKAG1, PTGDR, SDHC, SNCA, STAT3, SULT1E1, SULT1A3, SULT1C2, SULT2B1, TAZ, UQCRC1, UQCRC2, UQCRH, OGT, PAPSS1, SLC25A13 |
1417 | GO:0006357 | 0.01 | 1.67 | 27.07 | 39 | 119 | regulation of transcription from RNA polymerase II promoter | ABCA2, ACTL6A, KLF9, CHD2, CHEK1, ECM1, ERG, GSC2, HMGN1, HNF4G, MAZ, PAM, PRKAR1A, PTAFR, PURA, RBL2, RFX1, SMARCD3, SMARCE1, SOD2, SPIB, STAT2, ZNF354A, UBE2D2, UCP1, ZNF76, ZNF143, VEZF1, CUL2, SMARCA5, IKBKAP, BLZF1, RUVBL1, KLF7, CTDP1, LITAF, RNF14, ZNF518A, RBX1 |
1418 | GO:0051640 | 0.00 | 1.67 | 55.33 | 79 | 235 | organelle localization | AMPH, BIRC5, ARCN1, ARF1, ATP6AP1, BBS4, BICD1, BRCA2, CACNA1A, CANX, CAV3, CCNB1, CD59, CENPA, CENPE, CENPF, COPA, CSNK1D, DNM1, DYNC1H1, DNM2, GOLGA2, GRIA1, HHEX, ITGA4, LLGL2, NUBP1, NUMA1, P2RX7, PCM1, CHMP1A, PEX1, PEX13, PFN2, SEPT5, PPP6C, PTEN, PTK2, RAB1A, RAB5A, RAB6A, RAB27A, RAN, RB1, TRAPPC2, SNAP25, SNCA, SYN1, SYT1, SYT5, TACC1, DYNLT1, UVRAG, YWHAZ, CUL3, IKBKG, AP3B1, USO1, STX11, CDC23, LIN7A, SYNJ1, AP3D1, ARHGEF2, ZW10, COPB2, SNAP29, SLC9A3R1, KIF3B, NRXN1, GOSR1, SEC22B, GOSR2, CROCC, RIMS2, DLGAP5, AP1M2, ACTR2, SPRY1 |
1419 | GO:1903532 | 0.03 | 1.67 | 18.10 | 26 | 77 | positive regulation of secretion by cell | ATP6AP1, CHRNB2, CREB1, GALR1, GHRHR, GLRA1, INHA, KISS1, NTSR1, OXTR, PCP4, SEPT5, PTAFR, RAB5A, RAB27A, SDC4, SNCA, SOX11, SYT1, TSG101, VAMP8, ARHGEF7, SYT7, RAB9A, GAB2, PDCD6IP |
1420 | GO:0031098 | 0.00 | 1.66 | 33.56 | 48 | 142 | stress-activated protein kinase signaling cascade | CAV3, CHUK, CREB1, CRKL, CTGF, ELK1, EPHB1, ERCC6, PTK2B, FLT4, HGF, HMGCR, IGF1R, IL1A, IRAK1, IRAK2, JUN, MAP3K11, PRDX1, PPP2R5D, RAP2A, RBM4, RPS3, RPS6KA1, CCL21, SKP1, STK10, TP73, TPD52L1, NR2C2, TRAF2, UBB, FZD5, ARHGEF5, FZD4, FZD7, FZD8, CUL1, IKBKG, RIPK1, RIPK2, TRAF4, SLK, RB1CC1, ZEB2, OXSR1, SH2D3C, SH2D3A |
1421 | GO:0051050 | 0.00 | 1.66 | 62.49 | 89 | 269 | positive regulation of transport | ABAT, ABCA1, ABL2, AGTR2, ALOX15B, ANG, ANXA1, ATP2B2, ATP6AP1, BLK, TSPO, CAMK2A, CASP5, CD58, CHRNB2, CREB1, CRH, CSF1R, DPP6, DRD3, FGA, GALR1, GCG, GHRHR, GLRA1, GLUD1, GPLD1, FFAR1, FFAR3, IFNG, IL1A, IL10, INHA, INS, ISL1, KCNC2, KCNH2, KCNJ2, KCNJ11, KCNN4, KCNQ1, KISS1, KNG1, OXCT1, OXTR, P2RX1, P2RY2, PAEP, PCP4, SEPT5, PPID, PRKCE, PRKCI, PTAFR, RAB3B, RAB5A, RYR2, S100A1, S100A8, S100A9, SCN4B, SCN5A, SDC4, SGK1, SLC34A1, SOX11, STC1, SYT1, TRPM2, TNFSF4, SUMO1, NR1H2, TRPV1, WFS1, ARHGEF5, CLTCL1, PIK3R3, ARHGEF7, SYT7, RGN, SYNGR3, IL1RL1, RAB9A, LIPG, AKAP7, ATG5, PDCD6IP, SGK2, AKAP9 |
1422 | GO:0009132 | 0.04 | 1.66 | 14.65 | 21 | 62 | nucleoside diphosphate metabolic process | AK1, AK2, ALDOC, ARNT, BAD, ENTPD2, DLG2, DLG3, ENO2, GAPDH, IGF1, INS, OGDH, P2RX7, PGAM1, PPP2R5D, PRKAA1, PRKAG1, RRM2, STAT3, OGT |
1423 | GO:0042472 | 0.04 | 1.66 | 14.65 | 21 | 62 | inner ear morphogenesis | ALDH1A3, ATP2B2, BCR, COL11A1, DLX5, EPHB2, FGF3, FZD2, HMX2, INSIG1, OTX1, OTX2, RAC1, SOX9, CLRN1, WNT1, ZIC1, FZD6, HESX1, NRP1, SLC9A3R1 |
1424 | GO:0051983 | 0.04 | 1.66 | 14.65 | 21 | 62 | regulation of chromosome segregation | ATRX, BUB1B, CCNB1, CDC20, CDC27, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, PTEN, RB1, SFPQ, TTK, ZNF207, CUL3, CDC23, CDC16, ZW10, AURKB, DLGAP5 |
1425 | GO:1903214 | 0.04 | 1.66 | 14.65 | 21 | 62 | regulation of protein targeting to mitochondrion | ACTL6A, BNIP3L, CSNK2A2, CTSK, KAT2A, GPR26, NRG1, HNMT, RAC2, RNASE2, SREBF1, UBE2L3, ZBTB17, FZD5, BAP1, RUVBL1, CDKL2, BAG4, ATG13, FAM20B, SAE1 |
1426 | GO:1900182 | 0.04 | 1.66 | 15.36 | 22 | 65 | positive regulation of protein localization to nucleus | BMP4, BMPR1A, CDH1, EDA, FYN, HCLS1, IGF1, IL12B, IL18, INS, KPNA1, IPO5, SMAD3, PRKCQ, SLC9A1, TRIP6, ZIC1, OGT, TNFSF14, EIF2AK3, AKAP6, NUTF2 |
1427 | GO:0006260 | 0.01 | 1.66 | 25.88 | 37 | 110 | DNA replication | ACVRL1, BRCA2, CCNE1, CDC25A, CDC25C, CHEK1, E4F1, TYMP, HMGA1, HNRNPC, TONSL, NUP98, ORC1, ORC2, ORC4, PPP2R1A, PTMS, PURA, RAD51, RBBP6, RBMS1, UPF1, REV3L, RRM1, RRM2, S100A11, SET, SETMAR, SSRP1, TOP1, TTF1, CDK2AP1, CHAF1B, SMC1A, SMC3, RECQL5, RAD50 |
1428 | GO:0048813 | 0.04 | 1.66 | 16.07 | 23 | 68 | dendrite morphogenesis | ABL2, RERE, CACNA1A, CHRNB2, CTNND2, EFNA1, EPHB1, EPHB2, EPHB3, FYN, HPRT1, ILK, ITGB1, CAPRIN1, PTEN, RAC1, RAP2A, SGK1, PICALM, KLF7, RAPGEF2, CUL7, FARP1 |
1429 | GO:0045786 | 0.00 | 1.66 | 32.19 | 46 | 138 | negative regulation of cell cycle | ALOX15B, ATRX, BCL2L1, BMP4, BUB1B, CCNB1, CCNF, CDC20, CDC27, CENPF, CHEK1, CSNK2A1, CSNK2A2, ETS1, FGFR3, HHEX, NR4A1, HPGD, NUBP1, OVOL1, PRCC, PRKACB, PRKAR1A, PTEN, RPA2, RPL24, SIPA1, SMARCA4, SOX11, NR2F2, TOP2A, TOP2B, TTK, ZBTB17, ZNF207, SMC1A, TP63, CDC23, CDC16, LATS1, SMC3, ZW10, AURKB, SLC9A3R1, MAD2L1BP, CTDSPL |
1430 | GO:0031328 | 0.00 | 1.66 | 32.80 | 47 | 145 | positive regulation of cellular biosynthetic process | ABCA1, ANXA1, ASIP, AVPR2, CALM3, CD3E, CD4, TNFRSF8, CDK4, CIRBP, CRH, DAZ1, DRD5, EDNRA, EIF5A, ELAVL1, FSHR, GHRHR, GNAS, GOLGA2, GPLD1, GUCA1A, GUCA2A, GUCA2B, HRH1, HSPB1, HTR2C, IL12B, NTRK2, NTSR1, P2RY11, PTAFR, RCVRN, RPS6KB1, RPS6KB2, CCL21, SNCA, VIP, VIPR2, WFS1, NSMAF, DYRK2, RGN, AKAP12, GUCA1C, EIF4A3, EPM2AIP1 |
1431 | GO:0033554 | 0.00 | 1.66 | 125.35 | 176 | 546 | cellular response to stress | ADD1, ANXA1, ANXA5, APAF1, XIAP, ARG1, ASS1, ATP2A1, ATRX, BARD1, BCL2A1, BCL3, BMP4, BOK, BRCA2, CDK2, CDK3, CHD2, TPP1, COX8A, CRHBP, CSNK1D, CTH, CTLA4, CTNNA1, DDX1, DNM2, DNMT3B, DPEP1, EPHA2, EYA4, ERCC3, ERCC4, ETS1, ETV5, EXTL3, EYA2, F3, FANCE, FANCB, FANCF, FANCG, FEN1, GABRA5, GFAP, GRB2, HDGF, UBE2K, HMGN1, DNAJB2, IFNG, INSIG1, ISL1, ITPR1, KCNC2, KPNA2, FOXO4, TONSL, NTHL1, P2RX5, PENK, PEX13, PPP2CB, PPP5C, PRKD1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, RAD21, RAD23B, RAD51C, RAD51B, RAD51D, RBBP6, UPF1, REV3L, RFC3, RFC4, RFC5, RXRA, SCN2A, SGK1, SHC1, SIPA1, SLC12A1, SLCO1A2, SLC22A3, SUMO3, SNRPD1, SNRPF, SP100, SRF, SSRP1, STAT2, STAT6, STAU1, SULT1A3, TNFRSF1A, TNFRSF1B, TOP2A, HSP90B1, UBA7, UBE2E2, SUMO1, UNG, UVRAG, WNT1, XPA, XRCC2, XRCC5, YY1, TRIM25, ZNF189, RNF103, CHAF1B, SMC1A, HIST1H4I, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, DYRK2, SMARCA5, PARG, COPS3, CDC14B, PEA15, CRADD, TNFRSF10B, ALKBH1, EIF2B3, HERC2, MBD4, BAZ1B, ATP6V0D1, SMC3, EXO1, VAPB, COPS2, RECQL5, CHST3, PSMF1, CHD1L, GOSR2, CLOCK, KDM4A, PHYHIP, TATDN2, CUL7, DCLRE1A, USP3, FGFBP1, REC8, SLC12A6, IL18BP, COL4A3BP, RAD50, PSME3, DHRS2, PSMD14 |
1432 | GO:0007155 | 0.00 | 1.65 | 95.51 | 135 | 418 | cell adhesion | ACTB, ACTN1, AMBN, APP, ASTN1, ATP4B, AXL, BAX, BCL3, BGLAP, DST, ZFP36L2, BYSL, RUNX2, CD7, CD8A, CD9, TNFSF8, SCARB2, CD58, CD72, ADGRE5, CD151, CDH6, CDH7, CDH8, CDH9, CDH10, CDH12, CDH15, CCR3, CCR8, COL4A3, COL4A6, COL6A1, COL6A2, COL6A3, COL15A1, COMP, CLDN3, VCAN, CSRP1, CTGF, CTNNA1, CTNND2, CX3CR1, CXADR, EDA, CTTN, EPHB1, FAP, FLT3, B4GALT1, GNAS, GP1BA, GP9, RAPGEF1, GRID2, HSPB1, ICAM2, ICAM4, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, INS, INPPL1, ITGA1, ITGA9, ITGAD, ITGAM, KIT, SMAD6, KITLG, CD200, NRCAM, OMD, OLR1, P2RX7, PCDH7, PCDH8, PCDH9, PTPRS, PVR, RAB1A, RAB27A, RAG2, RAP2B, PRPH2, RPL22, S100A8, S100A9, SATB1, SELE, SELL, SELPLG, SHC1, SPAM1, STAT6, STK10, STXBP3, CNTN2, ICAM5, TPBG, TRIP6, TYRO3, ZAN, FZD5, MADCAM1, FZD8, SORBS2, CNTNAP1, STX11, CTNNAL1, SIGLEC5, NRP2, WISP3, CLDN12, CLDN10, CLDN8, CLDN6, CLDN1, SLIT2, NRXN3, NRXN1, NRXN2, BCAR1, SDC3, BCL2L11, GNE, TROAP, CHST4, GPA33, CD96 |
1433 | GO:0007126 | 0.03 | 1.65 | 18.91 | 27 | 80 | meiotic nuclear division | BRCA2, BRDT, CDC20, CDK2, ERCC4, GOLGA2, GPR3, ING2, PPP2R1A, PRKAR1A, RAD21, RAD51, RAD51C, RAD51B, RAD51D, TOP2A, TOP2B, UBB, XRCC2, SMC1A, FKBP6, SMC3, ZW10, REC8, SMC4, ACTR2, RAD50 |
1434 | GO:0060341 | 0.00 | 1.65 | 80.61 | 114 | 349 | regulation of cellular localization | ABCA2, ACTL6A, ATP1A2, BARD1, BAX, BCL2L1, BCL3, BMP4, BMPR1A, BNIP3L, BST2, CALM3, CASQ1, CASQ2, CAV3, CCNB1, CD4, CD36, CDH1, CDKN1A, CHRM1, CSNK2A2, CTSK, CYBA, DIAPH1, DKC1, DNM1, EDA, EDNRA, EPHA2, F2, PTK2B, FYN, GAS1, KAT2A, GDI1, GNAQ, GPR26, HCLS1, NRG1, HNMT, HRC, IL12B, IL18, INSIG1, ITGB1, KPNA1, IPO5, SMAD3, PPP1R12A, TONSL, OAZ1, OAZ2, P2RX3, P2RX4, P2RX5, PRDX1, PCM1, PLN, PPM1B, PRKCI, PRKD1, PTEN, PTN, PTPN6, RANGAP1, RB1, RBM4, RNASE2, RYR2, XCL1, SFRP5, SLC9A1, SP100, TNNC1, TRIP6, TRPC1, TRPC3, UBE2L3, VIL1, YWHAZ, ZIC1, ZBTB17, FZD5, AAAS, AKAP1, BAP1, FZD7, DYRK2, OGT, RGS20, RUVBL1, NUMB, DYNLL1, TNFSF14, INPP4B, SYNJ1, CDKL2, ITGB1BP1, SLC9A3R1, GSTO1, EIF2AK3, AKAP6, LITAF, GOSR1, TMEM59, BAG4, ATG13, C2CD5, FAM20B, BCL2L11, SAE1, NUTF2, RAMP3 |
1435 | GO:0006163 | 0.00 | 1.65 | 37.95 | 54 | 162 | purine nucleotide metabolic process | ACACB, ADSS, AK1, AK2, ALDOC, AMPD1, AMPD2, APRT, ATP1A2, ATP2B2, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1B2, ATP6V0A1, BAD, CACNB4, CAT, COX8A, COX15, CTNS, DLG2, DLG3, ENO2, GAPDH, GPX1, GUCY2C, GUCY2F, GUCY2D, HMGCR, HPRT1, HTR2C, IMPDH1, IMPDH2, LDHC, OGDH, PDE4B, PDE8A, PFAS, PPP2R5D, SDHC, SULT1E1, SULT1A3, SULT1C2, SULT2B1, TAZ, UQCRC1, UQCRC2, UQCRH, PAPSS1, SLC25A13 |
1436 | GO:0051346 | 0.00 | 1.65 | 56.48 | 80 | 239 | negative regulation of hydrolase activity | ABL1, ANXA1, BIRC3, XIAP, BIRC5, APLP2, APP, ARL2, BBS4, BICD1, BST2, C3, CD44, CNN3, COL4A3, COL6A3, CRY2, CSNK2A1, CST6, DLG2, DLG3, DPEP1, ECM1, SERPINB1, GPC3, GNAT1, GPX1, HGF, HRG, IFI16, IFIT1, ITIH1, ITIH4, KNG1, IPO5, LTF, SERPINE1, SERPINA5, SERPINF1, SERPINA4, SERPINB5, SERPINB9, SERPINB13, SERPINI2, PLN, PTPRN2, PZP, RAF1, RAG1, RENBP, RPS6KA1, SORT1, SERPINB4, SLPI, SNCA, SPINK1, SPOCK1, SERPINA7, TNNI3, TRAF2, VIL1, VTN, PICALM, SERPINB7, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, USP14, RGN, DGKI, KLF4, SLIT2, PSMF1, BAG4, RASA4, FARP1, SPRY1 |
1437 | GO:0051336 | 0.00 | 1.65 | 109.68 | 154 | 470 | regulation of hydrolase activity | ABL2, AGTR1, AGTR2, AMPH, ANG, APAF1, APOH, ARHGAP4, ARHGAP6, ARHGDIB, ARL1, AVPR1B, BAD, BAX, BCR, BOK, CALM3, CASP9, RCBTB2, CHN1, CHN2, CREB1, CTGF, CTSH, S1PR1, LPAR1, EDNRA, EFNA5, EIF2B1, EPHA2, EPHA5, EPHB3, F2R, F3, PTK2B, FBLN1, FGD1, FGFR3, FLT1, GCGR, GDI1, GDI2, GM2A, GNA15, GNAQ, GNAS, GPLD1, FFAR1, RAPGEF1, HIP1, ICAM1, IFNG, ITGA1, ITGB1, ITPR1, JUN, KIT, LLGL2, SMAD3, MGMT, PPP1R12A, NTRK2, NTRK3, OAS3, P2RX1, PCNA, PCOLCE, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRKD1, PSMA3, PTAFR, PTK2, RABIF, RANBP1, RANGAP1, RAP1GAP, RASA2, REST, RGS10, RGS12, RGS13, RPGR, RPS3, RSU1, S100A8, S100A9, SBF1, CCL21, CCL22, CCL25, XCL1, CX3CL1, SELE, SET, SIPA1, SOS2, XCL2, TBCD, DYNLT1, HSP90B1, TSC1, NR1H2, VAV1, WNT11, ARHGEF5, BCAR3, RGS20, TP63, S1PR4, CRADD, ARHGEF7, EIF2B3, EIF2B2, HERC2, RABEP1, ARHGEF1, ARHGEF2, VAPB, CCPG1, ITGB1BP1, GPR55, TRIP10, ARHGAP29, EIF2AK3, AKAP6, RIN1, RALGPS1, RAPGEF2, ARHGAP32, ACAP1, KIAA0141, ARHGEF11, NUAK1, SGSM2, ARHGAP25, TNFSF15, CASP8AP2, PDCD6, BCL2L11, SH2D3C, SH2D3A, PSME3, PSMD14, DENND4A |
1438 | GO:0050714 | 0.01 | 1.65 | 26.71 | 38 | 113 | positive regulation of protein secretion | ABAT, ABL1, ABL2, AGTR2, ALOX15B, ANG, ARF1, BAD, BLK, CASP5, CD58, CRH, CSF1R, F2R, FGA, FGR, GCG, GLUD1, GPLD1, FFAR1, IFNG, IGF1, IL1A, IL10, IL13, INS, ISL1, KCNN4, OXCT1, P2RX7, PAEP, PPID, PRKCE, PRKCQ, TRPM2, TNFSF4, NR1H2, IL1RL1 |
1439 | GO:0000122 | 0.00 | 1.65 | 90.99 | 128 | 385 | negative regulation of transcription from RNA polymerase II promoter | ACVR2B, AEBP1, NR0B1, ASCL1, ASCL2, RERE, ATRX, BACH1, PRDM1, BMI1, BMP4, KLF5, CD36, CDX2, CHD4, CRY2, DDX5, DNMT1, DNMT3B, DRD3, TSC22D3, E2F6, E4F1, EFNA1, EN1, EP300, ERF, ETV3, ETV6, FGFR3, GATA6, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HBE1, HCLS1, HDGF, HHEX, HIC1, FOXA2, HOXD8, HOXD9, HSF4, IFI16, IFNG, RBPJ, ISL1, JARID2, JUN, JUND, LMO1, SMAD3, SMAD7, CIITA, CNOT2, YBX1, ORC2, OVOL1, PAX3, PPID, RARA, RARB, RB1, REST, RXRA, S100A1, SALL1, SATB1, SFPQ, SIM2, SMARCA2, SMARCA4, SNAI1, SNCA, SOX3, SOX11, SP100, SREBF1, SRF, SRY, STAT3, STAT6, TAF7, TAL1, TBL1X, NR2F1, NR2F2, KLF10, TP73, NR2C1, UBB, SCGB1A1, NR1H2, WFS1, YY1, ZNF136, ZNF148, ZNF157, ZNF174, ZNF177, ZNF189, ZNF217, NRIP1, USP9X, FZD8, GFI1B, SOX14, UXT, CUL3, KLF11, TP63, EED, SAP30, PER3, RNF8, USP2, AURKB, KLF4, COPS2, RECQL5, HAND1, ZNF254, ST18, ZEB2, NR1H4, NR2E3, OLIG2 |
1440 | GO:0044089 | 0.02 | 1.65 | 23.19 | 33 | 99 | positive regulation of cellular component biogenesis | ATR, ADGRB2, BBS4, CLU, CTGF, LPAR1, EFNA5, EPHB1, EPHB2, EPHB3, HRG, KDR, KIT, LIMK1, SMAD3, CNOT2, NTRK2, NTRK3, OXTR, P2RX7, PIP4K2A, PTPRJ, SDC4, SOX9, TPBG, TSC1, TSG101, NR1H2, WNT11, ITGB1BP1, NRXN3, NRXN1, PDCD6IP |
1441 | GO:2000113 | 0.01 | 1.64 | 24.59 | 35 | 107 | negative regulation of cellular macromolecule biosynthetic process | ACVRL1, ADAR, ANG, ATF4, ATR, BMPR2, BRCA2, CIRBP, DAPK3, DUSP1, EIF4E, EPRS, GAPDH, GRB7, HNRNPC, EIF3E, KCNK2, CAPRIN1, SMAD1, RAN, RBM4, UPF1, RPS3, S100A11, SRP9, TSC1, TTF1, SMC1A, EIF4EBP3, EIF2B3, RGN, SMC3, EIF2AK3, TMEM59, EIF4A3 |
1442 | GO:0045944 | 0.00 | 1.64 | 118.96 | 166 | 505 | positive regulation of transcription from RNA polymerase II promoter | ACVRL1, APP, PHOX2A, ARNT, ARNTL, ASCL1, RERE, ATRX, BACH1, BCL3, BMP3, BMP4, BMPR1A, BMPR2, KLF5, CCNC, CCNT2, CD3D, CD28, TNFSF8, CDK8, CEBPE, CHUK, CREB1, CRX, DCN, DDX5, DRD3, ARID3A, EBF1, S1PR1, EGR2, ELK1, EN1, ERCC3, ESRRG, ETS1, ETV4, ETV5, ETV6, EVX1, EZH1, FGF4, FSHB, NR5A2, GALR1, GATA4, GATA6, GCG, KAT2A, HCLS1, HEXB, HGF, NRG1, HHEX, HMGA1, NR4A1, ONECUT1, HOXC11, HOXD8, HOXD9, HOXD10, HSF4, IFI16, IFNG, IGF1, IGF2, IHH, IL1A, IL10, INSIG1, IRF1, IRF5, ISL1, JUN, JUND, LMO1, SMAD3, SMAD7, MEOX2, CIITA, FOXO4, PPP1R12A, YBX1, OTX1, OTX2, SERPINE1, PAX3, PAX9, PCK1, PGR, PRKD1, PSMC1, PSMC2, PSMC3, PSMC4, RAD21, RAF1, RARA, RARB, RB1, REST, RFX3, RLF, RPS6KA1, SALL1, SIX3, SLC9A1, SMARCA2, SMARCA4, SOX9, SOX10, SOX11, SP1, SREBF1, SRF, STAT3, STAT4, STAT5B, STAT6, TAF7, TAL1, TBL1X, HNF1A, TNFRSF1A, TOP2A, TP73, NR2C2, UBB, UBE3A, NR1H2, WNT1, YY1, ZIC1, CNBP, ZSCAN21, ZNF148, FZD5, FOSL1, NRIP1, FZD8, OGT, IKBKG, STK16, TP63, RIPK1, RIPK2, BUD31, PHOX2B, RPS6KA4, CBFA2T2, ARHGEF2, CCPG1, ITGB1BP1, KLF4, HMGN3, HAND1, EIF2AK3, FHL5, ONECUT2, CLOCK, ZEB2, RNF10, NR1I3, NR1H4, NR2E3 |
1443 | GO:0007160 | 0.03 | 1.64 | 17.63 | 25 | 75 | cell-matrix adhesion | ACTN1, CD44, CD63, CTGF, DAPK3, EDA, EFNA5, CTTN, FGA, ONECUT1, ITGA1, ITGA4, ITGAV, ITGB1, PTK2, SLC9A1, SRF, CNTN2, TRIP6, VTN, MADCAM1, ARHGEF7, ONECUT2, SLK, BCL2L11 |
1444 | GO:0032970 | 0.00 | 1.63 | 44.67 | 63 | 189 | regulation of actin filament-based process | ABL1, ABL2, ADD1, ARF1, ARHGAP6, ATP1A1, ATP1A2, BBS4, BST2, CAPG, CAV3, CNN2, CSF1R, CTGF, DAPK3, S1PR1, LPAR1, EFNA5, CTTN, EPHA5, PTK2B, GATA4, GRB2, HCLS1, HRG, ICAM1, ILK, KCNJ2, LIMK1, SMAD3, NTRK3, PAM, PDE4B, PFN2, PLN, PRKCE, PRKCQ, RAC1, RYR2, SCN5A, CCL21, SDC4, SLC9A1, FSCN1, STC1, TNNC1, TSC1, SUMO1, VIL1, WNT11, ARHGEF5, LATS1, ITGB1BP1, SLIT2, PICK1, BAG4, SEMA3E, ARPC5, ARPC1B, ACTR2, ARPC2, ABI2, WASF2 |
1445 | GO:0048731 | 0.00 | 1.63 | 100.83 | 142 | 499 | system development | ADAM10, ALK, ARAF, ARF1, ARHGAP4, ASTN1, BCHE, DAGLA, CAMK2A, CD72, CDC20, CHN1, CHRM1, CHRM3, TBCB, AP2S1, CNR1, COL4A5, COL6A1, COL6A2, CSF2RB, CSNK2A1, CSNK2A2, CTNND2, DAPK3, BRINP1, DDX6, DHFR, DLG2, DLG3, DNM1, DNMT3B, DPYSL3, EPYC, DUSP5, EFNA3, EFNA4, EFNA5, ELAVL3, CTTN, EPHA8, GDI1, GFRA1, GJB1, GOLGA4, GRIN2A, ITGA1, ITGA9, KIF5A, LIMK1, CAPRIN1, MARK3, ATXN3, NTN3, OMP, OPA1, P2RX5, P2RY2, PALM, PENK, PPP2R5D, PPP5C, PRKACB, PRKCQ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTPRA, PTPRR, PURA, RAC2, RALA, RAP2A, RASA2, RNF6, SCN2A, SDHA, SFRP5, SGK1, SMARCE1, SNAP25, STRN, DYNLT1, TPBG, TRPC1, TRPC3, TRPC5, TTC3, XRCC2, ZNF24, RNF112, ZNF217, SLC7A5, RND2, DPF1, SOX14, CNTNAP1, GAS7, KLF7, PEA15, BSN, RPS6KA4, ARHGEF1, CBFA2T2, ARHGEF2, NRXN2, PICK1, CHST3, PSMF1, BAG5, FEZ2, RIMS2, SPOCK2, ARHGEF11, KIAA0319, RNF10, NR1H4, RBX1, RANBP9, ARPC5, ARPC1B, ACTR2, ARPC2, RASA4, ATP6AP2, FARP1, PSME3, PSMD14 |
1446 | GO:0002460 | 0.04 | 1.63 | 16.24 | 23 | 69 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | BCL3, BTK, C7, CD8A, CLC, CLU, CR2, CTSH, EMP2, ICAM1, IFNA2, IL10, IL13RA2, IL18, PTPN6, RAB27A, ADAM17, STX11, TNFSF18, RNF8, EXO1, IL1RL1, IL18BP |
1447 | GO:0044093 | 0.05 | 1.63 | 14.73 | 21 | 66 | positive regulation of molecular function | ADD1, KRIT1, EPB41, KAT2A, IGF1, ISL1, KCNJ11, NTSR1, RAN, RARA, RFNG, S100A1, SGK1, SLC9A1, VTN, NRP1, BAZ1B, SYNGR3, GSTO1, AKAP7, SGK2 |
1448 | GO:0033365 | 0.00 | 1.63 | 123.84 | 172 | 524 | protein localization to organelle | ACTL6A, ADAR, AGTR2, ANGPT1, ARL1, ARL2, ARNTL, RERE, ATR, ATRX, BAD, BAX, BBS4, BCL3, BICD1, BMP4, BMPR1A, BNIP3L, BRCA2, BUB1B, TSPO, CBLB, CD36, SCARB2, CDH1, CDKN1A, CENPA, COL1A1, CSE1L, CSNK1D, CSNK2A2, CTSK, DDX1, DIAPH1, DKC1, EDA, F2R, FAU, FYB, FYN, KAT2A, GFER, GNAQ, GOLGA4, GPR26, HIST1H1B, HCLS1, NRG1, HHEX, HNMT, HSPA4, HSPA9, IFNG, IGF1, IL10, IL12B, IL18, INS, JUN, KPNA1, KPNA2, KPNA3, KPNA4, IPO5, SMAD3, TONSL, YBX1, NUP98, PRDX1, PCM1, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PPM1B, PRKCQ, PEX19, PEX5, RAB6A, RAC2, RAD21, RAN, RANBP2, RB1, RNASE2, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, RYR2, SFRP5, STIL, SIX3, SLC9A1, SUMO3, SOX9, SREBF1, SRP9, SRP14, STAT3, TRIP6, TULP1, TULP2, TULP3, UBE2L3, SUMO1, WRB, YWHAZ, ZIC1, ZBTB17, FZD5, NUP214, AKAP1, BAP1, FZD7, DYRK2, OGT, AP3B1, RGS20, RUVBL1, AKR1C3, DYNLL1, TNFSF14, NRP1, AP3D1, CDKL2, RPL14, ZW10, AURKB, TRIP11, RPL23, SLC9A3R1, ZFYVE9, PEX16, EIF2AK3, AKAP6, LITAF, BAG4, NUP155, IPO13, NUP93, CROCC, IFT140, ZFYVE16, ATG13, TOMM20, KLHL21, FAM20B, BCL2L11, SAE1, ARFRP1, NUTF2 |
1449 | GO:0002221 | 0.02 | 1.62 | 22.69 | 32 | 96 | pattern recognition receptor signaling pathway | BIRC3, XIAP, BTK, CD86, CD36, CHUK, CREB1, CTSK, CYBA, DMBT1, ELK1, IRAK1, IRAK2, IRF1, ITGAM, JUN, LTF, PPP2R5D, PRKCE, RPS6KA1, SEC14L1, SKP1, HSP90B1, TYRO3, UBB, UBE2D2, CUL1, IKBKG, RIPK1, RIPK2, TRIL, NR1H4 |
1450 | GO:0002009 | 0.00 | 1.62 | 57.76 | 81 | 245 | morphogenesis of an epithelium | ABL1, ABL2, ACVRL1, AGTR2, ALDH1A3, APAF1, BAX, BBS4, CAV3, CHUK, CSF1R, CTSH, DLG3, EDNRA, EPHA2, ETV4, ETV5, GPC4, FGF3, FGF7, FGFR3, FZD2, GATA4, KAT2A, B4GALT1, GPC3, GRB2, HGF, HHEX, FOXA2, RBPJ, IHH, IL10, ILK, ITGA5, KDR, LLGL2, SMAD3, OPA1, PAX3, PCDH8, PGR, SERPINB5, PRKACB, PRKX, PSPN, RAC1, RALA, RARA, RYK, RYR2, SALL1, SCNN1B, SDC4, STIL, SLC12A2, SNAI1, SOX10, SOX11, SRF, ST14, ADAM17, TSC1, TULP3, KDM6A, WNT1, WNT11, FZD5, FZD6, FZD7, NUMB, HESX1, NRP1, SOCS3, KLF4, SLIT2, SLC9A3R1, HAND1, SEMA3E, ZEB2, SPRY1 |
1451 | GO:0015758 | 0.02 | 1.62 | 21.98 | 31 | 93 | glucose transport | C3, EDNRA, G6PC, GPC3, FFAR3, NRG1, IGF1, INS, NUP98, PRKAA1, PRKCI, RANBP2, RPS6KB1, RTN2, SORT1, SLC2A3, SLC2A4, SLC2A5, SLC5A2, STXBP3, HNF1A, TSC1, VIL1, NUP214, AAAS, CLTCL1, PIK3R3, PEA15, NUP155, NUP93, C2CD5 |
1452 | GO:0051234 | 0.00 | 1.62 | 345.85 | 458 | 1512 | establishment of localization | ABCA2, ABCA3, ABCB7, ABCA4, ACACB, ACTB, ACTN1, ADD1, AGTR1, ALB, ABCD1, AMPH, ANXA3, ANXA6, ANXA11, BIRC5, APOH, APP, APRT, AQP5, AQP6, ARG1, ARL1, ARR3, ASGR1, ATF4, ATP1A1, ATP1A2, ATP1A3, ATP12A, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP4A, ATP4B, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATR, KIF1A, AVPR2, AXL, BCL2A1, BCR, BGLAP, BICD1, BST2, C3, CA4, CACNA1B, CACNB4, CALM3, CAMK2A, CASQ1, CASQ2, CBL, CCNB1, CD4, CD5, CD6, CD9, CD59, CDK2, CDO1, CDX2, CEBPE, CENPA, CENPE, CHAT, AKR1C4, CHRNB2, CHRNB4, CHUK, CLCA1, CLCN3, CLCN6, CLCN7, CLCNKA, CLCNKB, CLNS1A, CNGA1, CNP, COMT, COX6A1, COX6B1, COX7A1, COX7C, COX8A, COX15, CPT1B, CPT2, CRAT, CREB1, CRHBP, CRY2, CSNK1D, CTGF, CTNS, CXADR, CYB5A, CYBA, DBI, ACE, DIAPH1, DNM1, DYNC1H1, DPP6, TSC22D3, EDNRA, EIF4E, EMP2, EYA2, F2, F7, F10, FABP2, FABP7, PTK2B, FCGRT, FCN2, FGF7, FTL, FYN, G6PC, GABRA4, GABRA5, GABRE, GABRG1, GABRR1, GABRR2, GAD1, GALR1, GAS1, GCGR, GDF9, GFAP, B4GALT1, GHRHR, GIF, GJA3, GJA4, GJB1, GPC3, GLRA1, GM2A, GOLGA2, GOLGB1, GOT2, GPM6A, XCR1, FFAR3, GRB2, GRIA1, GRIA4, GRID1, GRID2, GRIN2A, GUCA2B, HBA2, HBD, HBE1, HGF, HHEX, HIP1, HP, HPX, HRC, HRG, HTR2C, ICAM1, IGF2, IL13RA2, INHA, INPPL1, INSIG1, ITGA4, ITGAV, KCNA1, KCNA3, KCNA4, KCND2, KCND3, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNQ1, KCNS2, KIF5A, KISS1, KIT, KNG1, LCAT, LIMK1, LIPC, LRPAP1, LTF, MAL, MYO1B, PPP1R12A, NTRK2, NTSR1, NUMA1, OLR1, OPA1, ORM2, OSBP, OXTR, P2RX1, P2RX3, P2RX4, P2RX5, P2RY2, P2RY4, P2RY6, SERPINE1, SERPINA5, PCP4, PDE4B, PFN2, FXYD3, PLN, SEPT5, PPP6C, PRKAA1, PRKD1, PROC, PSAP, PTAFR, PTEN, PTGS1, PTK2, PTPN6, ABCD3, ABCD4, RAC1, RALA, RANBP1, RAP1GAP, RARA, RB1, RBM4, RBP1, RBP2, RCVRN, UPF1, RHAG, RHCE, RHD, RPS6KB1, RXRA, RYR1, S100A1, SORT1, S100A8, S100A9, SCN1A, SCN2A, SCN4B, SCN5A, SCN7A, SCN8A, SCNN1A, SCNN1B, SCNN1G, SCO1, CCL21, XCL1, SDC4, SEC14L1, TRAPPC2, SELE, SELP, SET, SRSF1, SRSF5, SRSF7, SFTPD, SGK1, SLC1A6, SLC2A3, SLC2A4, SLC2A5, SLC4A1, SLC5A2, SLC6A6, SLC6A7, SLC6A13, SLC7A1, SLC7A4, SLC8A3, SLC9A2, SLC9A3, SLC10A1, SLC12A2, SLC13A1, SLC34A1, SLC20A1, SLCO2A1, SLCO1A2, SLC22A1, SLC22A3, SLC22A2, SLC22A5, SNCA, SOX11, SPARC, SPINK1, STAT5B, STC1, SYN1, SYP, SYPL1, SYT1, SYT4, TAF7, SERPINA7, DYNLT3, ICAM5, TNNC1, TP73, TPD52, TPT1, TRPC1, TRPC3, TRPC4, TRPC5, TSC1, TUBA4A, TULP1, TYRO3, UBB, UBE3A, SUMO1, UCP1, UPK3A, UQCRC1, UQCRH, UVRAG, VAV1, VDAC2, VEGFB, TRPV1, VTN, LAT2, WFS1, ZFPL1, SLC30A2, LAPTM5, TUBA1A, KCNAB1, TUSC3, SLC25A16, FGF23, ANP32A, SLC7A5, SLC14A2, SYN3, SLC10A3, DYSF, PICALM, FZD4, UXT, EEA1, CUL3, PIK3R3, IKBKG, KHSRP, SLC25A12, PEA15, SRSF9, CDC23, RIPK1, INPP4B, NRP1, PROZ, SYNJ1, ARHGEF7, SLC5A6, EIF2S2, SLC13A2, CLDN10, RGN, SLC16A6, SLC16A5, SYNGR3, SLC6A5, DGKI, KCNAB3, VAPB, PDLIM7, TRIP10, CD163, NRXN3, KIF3B, SLC22A8, NRXN2, LIPG, KCNK6, GSTO1, AKAP7, SLC4A7, MPDU1, RIN1, SNCAIP, CLINT1, CROCC, EIF4A3, PIEZO1, DLGAP5, CKAP5, SCRN1, DNAJC6, GAB2, ZC3H11A, OSBPL2, SMG7, SV2B, SGSM2, RBM8A, OXSR1, GOLGA5, SLC12A6, HCN4, ABCC5, ABCB6, ABCC9, ABCF2, ATP9A, COL4A3BP, ARPC5, ARPC1B, ACTR2, ARPC2, SGK2, AKAP9, G3BP1, WASF2, SLC25A13, SLC25A15, PRG4, SLC35B1, KCNMB2, SPRY1, ABCC4 |
1453 | GO:0007416 | 0.03 | 1.62 | 19.14 | 27 | 81 | synapse assembly | APP, ADGRB2, CACNA1A, CDH1, CHRNB2, EFNA5, EPHB1, EPHB2, EPHB3, GHSR, GPM6A, NRG1, NRCAM, NTRK2, NTRK3, OXTR, PTEN, PTK2, RYK, TPBG, FZD5, BSN, NRXN3, NRXN1, NRXN2, SPOCK2, FARP1 |
1454 | GO:0031344 | 0.02 | 1.62 | 21.97 | 31 | 94 | regulation of cell projection organization | ABL1, ARHGAP4, CACNA1A, CDC20, CHN1, CHRNB2, DCC, EFNA1, CTTN, EPHB3, GDI1, GFAP, GRID2, NRCAM, PTEN, PTK2, RAP2A, RNF6, SEMA3F, SNAP25, SPOCK1, CNTN2, TNR, VIM, SEMA3B, ARHGEF1, KLF4, BAG5, AATK, SEMA3E, KIAA0319 |
1455 | GO:0006468 | 0.01 | 1.62 | 30.35 | 43 | 137 | protein phosphorylation | ADAM10, BIRC5, BUB1B, CDK11B, CDK2, CDK3, CDK6, CDK8, CHEK1, CSNK1G3, CSNK2A1, CSNK2A2, ERCC3, ERG, FYB, GUCY2C, GUCY2F, GUCY2D, LIMK1, LIPE, SMAD9, PDK4, PHKA2, PHKB, PHKG1, PRKCI, PRKCQ, PSKH1, RARA, RPS6KB1, RPS6KB2, SGK1, SRPK2, STAT4, RIOK3, CDKL1, CDKL2, STK17A, PICK1, CDC42BPB, NUAK1, COL4A3BP, SGK2 |
1456 | GO:0009267 | 0.04 | 1.62 | 16.31 | 23 | 69 | cellular response to starvation | ALB, ATF4, BMPR2, CDKN1A, COMT, IFI16, JUN, PCK1, PDK4, PRKAA1, RHAG, RHCE, RHD, SRD5A1, SREBF1, KLF10, UPP1, PPM1D, AKR1C3, EIF2AK3, PICK1, ATG5, ATG13 |
1457 | GO:0010771 | 0.05 | 1.62 | 15.60 | 22 | 66 | negative regulation of cell morphogenesis involved in differentiation | ARHGAP4, DCC, EFNA1, FBLN1, GDI1, FOXA2, SMAD7, PTEN, PTK2, RNF6, SALL1, SEMA3F, TNR, TTC3, SEMA3B, NRP1, ARHGEF1, ITGB1BP1, SLIT2, AATK, RAPGEF2, SEMA3E |
1458 | GO:0034605 | 0.05 | 1.62 | 15.60 | 22 | 66 | cellular response to heat | ATR, CAMK2A, CDKN1A, EP300, HSPA6, IL1A, IRAK1, ATXN3, NUP98, RANBP2, RPA2, RPA3, DNAJC7, NUP214, AAAS, BAG5, BAG4, BAG3, NUP155, NUP93, HDAC6, PDCD6 |
1459 | GO:0000904 | 0.05 | 1.62 | 15.54 | 22 | 68 | cell morphogenesis involved in differentiation | ACTN1, BMP4, CASP9, COL1A1, CLDN3, CRYGB, EP300, ERG, HGF, RBPJ, IHH, SMAD3, PTPN6, S100A4, SNAI1, SOX9, ST14, STC1, TAL1, WNT11, ADAM15, LATS1 |
1460 | GO:0051129 | 0.00 | 1.62 | 66.62 | 93 | 283 | negative regulation of cellular component organization | ADD1, ATRX, BBS4, BCL2L1, BMP4, BUB1B, TSPO, CAPG, CAV3, CCNB1, CCNF, CDC20, CDC27, CENPF, CHEK1, CLU, CSNK2A1, CSNK2A2, DFFA, DNM2, DNMT1, DNMT3B, DPP4, DPYSL3, DUSP1, S1PR1, LPAR1, ERCC4, FAP, EFEMP1, FGFR3, GFAP, GPX1, HGF, HMGA1, HNRNPC, HRG, DNAJB2, IGF1, INS, INSIG1, ITGB1, JARID2, SMAD6, NUBP1, OPA1, PFN2, PHF2, PRKAR1A, PRKD1, PTN, PEX5, RAC1, RAF1, RAP1GAP, CCL21, SET, SETMAR, SGK1, SNCA, SPOCK1, SYT4, TAF7, TBCD, TTK, NR1H2, VDAC2, VIL1, VIM, XRCC5, ZNF207, PICALM, OGT, NUMB, CDC23, CDC16, UNC119, CBFA2T2, ARHGEF2, ZW10, AURKB, NRXN1, PICK1, ATG5, TMEM59, BAG5, BAG4, FEZ2, KDM4A, KIAA0319, HDAC6, RAD50, WASF2 |
1461 | GO:0015980 | 0.02 | 1.62 | 23.46 | 33 | 100 | energy derivation by oxidation of organic compounds | ACO2, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, BAX, CAT, COX6A1, COX6B1, COX7C, COX8A, COX15, CYC1, IDH1, IDH3A, MDH2, OGDH, SDHA, SDHB, SDHC, SDHD, SNCA, TAZ, UCP1, UQCRC1, UQCRC2, UQCRH, SLC25A12, SUCLG1, TRAP1, SLC25A13 |
1462 | GO:0051260 | 0.01 | 1.61 | 27.10 | 38 | 115 | protein homooligomerization | ALAD, ANXA5, ANXA6, APAF1, ARG1, BAX, ENTPD2, CLU, CLDN3, DPYSL3, GLRA1, HSF4, KCNA1, KCNA3, KCNA4, KCNC2, KCND2, KCND3, KCNS2, KCNS3, P2RX1, P2RX3, P2RX4, PAM, PLN, RAD51, SLC34A1, SLC22A1, SYT1, TAF10, TRAF2, CLPP, OGT, RIPK1, HRK, CLDN1, EIF2AK3, BCL2L11 |
1463 | GO:0044767 | 0.00 | 1.61 | 55.19 | 78 | 282 | single-organism developmental process | ALDH3A2, AMELY, ARHGDIB, STS, ARSE, TNFRSF17, BST2, CBLB, TNFRSF8, CENPE, CHRM1, CHRM3, CLC, DDX1, DLG2, RCAN1, EBF1, PHC2, EYA4, EXTL1, GABRA4, GJB1, GNRH2, GNRHR, HIC1, HIVEP2, IDH1, IDO1, INSRR, KRT9, MATN3, ATXN3, DRG1, OMD, P2RX5, PAEP, PRDX1, PCOLCE, PIM1, PPP2R5D, PRKACG, PTGDR, PTPRN, RPS4Y1, SCN2A, SDHA, TRAPPC2, CLEC3B, TPBG, SCGB1A1, UNG, ZNF7, ZNF24, ZNF45, ZNF74, RNF103, DPF1, NRIP1, SMC1A, JRKL, TRADD, EED, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, VNN2, BSN, PAPSS1, CLDN1, SMC3, EXO1, NRXN2, IL27RA, ADAMTS4, MINPP1, TRAF4, ZNF256 |
1464 | GO:0051248 | 0.00 | 1.61 | 152.43 | 209 | 645 | negative regulation of protein metabolic process | ABL1, ADAR, ANG, ANGPT1, BIRC3, XIAP, BIRC5, APLP2, APP, ATF4, BAX, BCL3, BMP4, BST2, BUB1B, TSPO, C3, CALM3, CAV3, CCNB1, CD44, CD59, CDC20, CDC27, CDKN1A, CENPF, CHAD, CIRBP, CLU, COL4A3, COL6A3, CRY2, CRYBA1, CSNK2A1, CSNK2A2, CST6, DAPK3, DCN, DLG2, DLG3, DNMT1, DNMT3B, DPEP1, DUSP1, DUSP5, ECM1, EIF4E, SERPINB1, EPRS, F2, FBLN1, FGA, FLOT2, FYN, GAPDH, GAS1, GHSR, GPC3, GNAQ, GP1BA, GPX1, GRB7, RAPGEF1, GRIN2A, HGF, NRG1, HHEX, HMGCR, HRG, DNAJB2, HSPB1, IFI16, IGF1, IGF1R, IGFBP3, IL10, ILK, INHA, INS, EIF3E, ITGAV, ITIH1, ITIH4, JARID2, JUN, KNG1, LIMK1, CAPRIN1, SMAD1, SMAD3, SMAD6, SMAD7, CNOT2, NTRK3, P2RX7, SERPINE1, SERPINA5, PCP4, SERPINF1, SERPINA4, SERPINB5, SERPINB9, SERPINB13, SERPINI2, PPP2R1A, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTPN6, PTPRJ, PTPRR, PURA, PZP, RAF1, RAG1, RAN, RARA, RB1, RBM4, RENBP, UPF1, RPS3, RPS6KA1, SERPINB4, SET, SFTPD, SLPI, SNCA, SNRNP70, SPINK1, SPOCK1, SRP9, TRIM21, TAF7, SERPINA7, NR2F2, TP73, TRAF2, TSC1, TTK, UBB, USP4, NR1H2, VIL1, VTN, WNT1, ZNF207, AKAP1, PICALM, CUL3, OGT, EIF4EBP3, CDC23, SERPINB7, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, CDC16, EIF2B3, SOCS3, USP14, RGN, LATS1, ZW10, ITGB1BP1, SOCS6, KLF4, SLIT2, SLC9A3R1, EIF2AK3, ATG5, PSMF1, TMEM59, BAG5, BAG4, KDM4A, EIF4A3, HDAC6, RANBP9, FARP1, PSME3, PSMD14, PRG4, CTDSPL, SPRY1 |
1465 | GO:0016458 | 0.01 | 1.61 | 29.31 | 41 | 124 | gene silencing | ADAR, CDK2, DNMT1, DNMT3B, HIST1H2AD, HMGA1, KCNQ1, SMAD1, SMAD3, CNOT2, NUP98, CHMP1A, PHF2, RAN, RANBP2, RBM4, TBP, TSN, NUP214, AAAS, HIST1H4I, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, FKBP6, HAT1, HIST1H3F, HIST1H2AG, TAF1B, TAF1A, NUP155, NUP93 |
1466 | GO:0031667 | 0.00 | 1.61 | 41.48 | 58 | 178 | response to nutrient levels | ACACB, ACADS, ACTL6A, ATF4, ATP6V0A1, BBS4, BMPR2, BNIP3L, CDKN1A, CLPS, COMT, CPS1, CSNK2A2, CTSK, CYBA, DCN, CTTN, G6PC, GCG, KAT2A, GHSR, HTR2C, ICAM1, IFI16, IGF2, JUN, KDR, LIPC, PCK1, PDK4, PIP4K2A, PRKAA1, PSPH, RHAG, RHCE, RHD, SLC22A3, SORD, SRD5A1, SREBF1, KLF10, TSC1, UPP1, TRPV1, WNT11, ZBTB17, FZD5, PPM1D, RUVBL1, SOCS3, SLIT2, RAB33A, EIF2AK3, PICK1, ATG5, FEZ2, ATG13, HDAC6 |
1467 | GO:0010506 | 0.01 | 1.61 | 26.44 | 37 | 112 | regulation of autophagy | ABL1, ABL2, ACTL6A, ATP6V0A1, BAD, BCL2L1, BNIP3L, TSPO, CSNK2A2, CTSK, DAPK3, DCN, CTTN, GATA4, KAT2A, GOLGA2, HGF, IFI16, IFNG, KDR, KIF25, PIP4K2A, PRKAA1, SREBF1, TRIM21, TSC1, UVRAG, ZBTB17, FZD5, RUVBL1, RAB33A, ATG5, TMEM59, FEZ2, KDM4A, RB1CC1, HDAC6 |
1468 | GO:0006898 | 0.04 | 1.61 | 17.84 | 25 | 76 | receptor-mediated endocytosis | ALB, ASGR1, CD5, CD6, AP1S1, COL1A1, DMBT1, CTTN, EPS15, FTL, HBA2, HP, HPX, LRPAP1, OLR1, RAC1, SFTPD, SLC9A3, SPARC, HSP90B1, CLTCL1, PDLIM7, CD163, SNX17, PRG4 |
1469 | GO:0044763 | 0.00 | 1.60 | 185.16 | 236 | 1107 | single-organism cellular process | ABCA2, ABCA3, ABCB7, ABO, ACY1, ADSS, AHCY, AK1, AK2, AMPD1, AMPD2, APRT, AQP5, AQP6, ARCN1, ARG1, ARG2, ART1, ASL, ASS1, ATP2B3, ATP4B, AUH, BCKDHA, CA4, CAPN6, CDH7, CDH9, CDH10, CDH12, CDO1, CD52, CHD4, CKM, CLCA1, CLCN7, CLCNKA, CLCNKB, CLNS1A, COPA, COX7A1, CTNS, CYB5A, CYP8B1, DBT, CYB5R3, DKC1, SARDH, E2F6, ENO2, EPRS, ESD, EXTL1, EZH1, FBLN2, FCN2, FTL, FUT6, GALNS, GATM, GIF, GLDC, GOLGB1, GPT, GSTZ1, GUCA2A, GUCA2B, HIST1H1B, HARS, HLCS, HNMT, DNAJB2, HSPA4, ICAM4, IDS, KRT5, KRT9, LIM2, MATN3, MFAP3, MGAT2, CD200, OAT, OMD, ORC1, ORC2, ORC4, OVGP1, OVOL1, P4HA1, PAH, SERPINA5, PEPD, PEX1, PEX6, PEX10, PEX12, PFAS, CFP, PGAM1, FXYD3, PPIB, PPP2R2A, PPP6C, PRCC, PRIM2, PRPSAP1, PSPH, PVR, PEX19, ABCD4, PEX5, QDPR, RBL2, RENBP, RPE, RRM1, RRM2, RTN2, SCNN1A, SCNN1G, SCO1, TRAPPC2, SRSF5, SHMT1, SHMT2, SLC2A3, SLC2A5, SLC4A1, SLC5A2, SLC6A6, SLC6A7, SLC7A1, SLC7A4, SLC9A2, SLC9A3, SLC10A1, SLC12A2, SLC13A1, SLC15A1, SLC34A1, SLCO2A1, SLC22A1, SLC22A5, SMS, SPAG4, SPAM1, SRP9, SRP14, SULT1C2, SULT2B1, SUOX, TAF10, TAT, TBCD, TPBG, TUBG1, TUFM, TULP2, TYR, UBE2E2, UBE2L3, UGT2B7, VBP1, ZAN, WRB, ZNF91, SLC30A2, PRDM2, RNF103, TUSC3, SLC25A16, CDK2AP1, SLC14A2, SLC10A3, DYSF, BAP1, GFI1B, EEA1, DDO, BLZF1, USO1, DDX3Y, ALDH4A1, GALNT4, B4GALT3, B3GALT2, EED, RIOK3, CDKL1, SLC5A6, EIF2S2, P4HA2, SLC13A2, PAPSS1, CLDN12, CLDN6, CLDN1, USP2, SEC22C, SLC16A6, SLC16A5, CCPG1, COPB2, GTF3C4, B4GALT6, SLC22A8, COG1, PEX16, ADAMTS2, GOSR1, TMEM59, TP53I3, SEC22B, MINPP1, CEP135, KIAA0391, SETD1A, FRMPD4, PIEZO1, RNF40, GINS1, CEP350, SV2B, XYLB, HS3ST3B1, DMTF1, AP1M2, SAE1, ABCC5, ABCB6, ATP9A, SLC25A15, CTDSPL, SLC35B1, ZMPSTE24 |
1470 | GO:0051048 | 0.02 | 1.60 | 25.05 | 35 | 106 | negative regulation of secretion | ABAT, AGTR2, ANGPT1, ANXA1, ANXA5, AVPR2, BCR, CNR1, COMT, CRH, CRHBP, DRD3, F2R, FBLN1, GHSR, NRG1, HMGCR, IFNA2, IL10, IL13RA2, INHA, INS, KCNJ11, OXTR, PTGS1, REST, CX3CL1, SNCA, SREBF1, STXBP3, SYT4, TNFSF4, FGF23, VAMP8, NR1H4 |
1471 | GO:0008202 | 0.00 | 1.60 | 38.76 | 54 | 164 | steroid metabolic process | ABCA1, AGTR1, NR0B1, ALB, APLP2, APP, STS, ATP1A1, TSPO, CAT, AKR1C4, COMT, CRH, CYP2A6, CYP3A4, CYP8B1, CYP11B1, DHCR7, CYB5R3, FDFT1, FDPS, FSHB, NR5A2, G6PC, HMGCR, HMGCS2, FOXA2, HSD11B1, IFNG, INSIG1, LCAT, LIPC, LIPE, PRKAA1, REST, RXRA, SLC10A1, SLCO1A2, SNAI1, SRD5A1, SREBF1, STAT5B, SULT1E1, SULT1A3, SULT2B1, TNFSF4, UGT2B7, CNBP, FGF23, AKR1C3, SNX17, NR1H4, DHRS9, DHRS2 |
1472 | GO:0007166 | 0.00 | 1.60 | 86.23 | 120 | 403 | cell surface receptor signaling pathway | ABCA1, ACPP, ANXA1, ARNTL, ATP1A3, ADGRB2, BCL2A1, BCL2L1, PRDM1, BOK, BSG, CCNE1, CD6, CD9, CD36, CD37, CD59, ADGRE5, CD151, CDA, COL1A1, COL4A3, CRH, CRHBP, CSNK1D, CSNK1G3, CSNK2A1, CSNK2A2, CTNND2, DAPK3, DBH, DCC, CTTN, EYA2, F2, GPC4, FGA, FZD2, GAS1, GCGR, GNAQ, GPR19, GPX1, GRIA1, GRIA4, GRID1, GRM1, HIC1, IHH, IL18, ISL1, CD82, LTF, MAL, MGAT3, OXTR, P2RX1, P2RX3, P2RX5, P2RX7, P2RY2, P2RY4, P2RY6, PPP2R1B, PTH2R, RAB5A, RB1, PRPH2, RYK, SALL1, TSPAN31, SCTR, SEMA3F, SFRP5, STIL, SIX3, SMARCA4, SOX10, STRN, CNTN2, TSPAN7, TULP3, UPK1B, KDM6A, VIPR2, TRPV1, WNT11, ZIC1, FZD5, SCG2, SEMA3B, FZD6, FZD7, FZD8, FZD9, DYRK2, RGS20, UNC5C, SSNA1, PTCH2, CRADD, TNFSF10, LATS1, BCL7B, KLF4, GLP2R, BAG3, SEMA3E, IFT140, KIAA0141, RB1CC1, ZEB2, P2RY14, CASP8AP2, ZBTB33, FRAT1, FEM1B, G3BP1, ATP6AP2, RNF41 |
1473 | GO:0007254 | 0.02 | 1.60 | 22.22 | 31 | 94 | JNK cascade | CRKL, CTGF, EPHB1, ERCC6, PTK2B, FLT4, IGF1R, IL1A, IRAK1, IRAK2, MAP3K11, RAP2A, RPS3, CCL21, TP73, TPD52L1, TRAF2, UBB, FZD5, ARHGEF5, FZD4, FZD7, FZD8, IKBKG, RIPK1, RIPK2, TRAF4, RB1CC1, ZEB2, SH2D3C, SH2D3A |
1474 | GO:0009913 | 0.03 | 1.60 | 20.80 | 29 | 88 | epidermal cell differentiation | ALOX15B, ANXA1, ATP2B2, BMP4, DNASE1L2, EPHA2, ERCC3, EVPL, RBPJ, KRT2, RAC1, S100A7, SPRR2A, SPRR2D, SPRR2E, SPRR2G, SPRR3, ST14, TSG101, CLRN1, MADCAM1, TP63, PTCH2, AKR1C3, SCEL, LATS1, KLF4, SLC9A3R1, SLC4A7 |
1475 | GO:1903510 | 0.03 | 1.59 | 19.38 | 27 | 82 | mucopolysaccharide metabolic process | ANGPT1, CD44, VCAN, CSPG4, DCN, GPC4, GALNS, B4GALT1, GPC3, HEXA, HEXB, HGF, IDS, IDUA, ITIH1, ITIH4, OMD, PIM1, SDC4, SLC9A1, B4GALT4, B4GALT3, B4GALT6, CHST3, SDC3, SPOCK2, ABCC5 |
1476 | GO:0009119 | 0.00 | 1.59 | 43.25 | 60 | 183 | ribonucleoside metabolic process | ACACB, ACPP, ADSS, AHCY, AK1, AK2, ALDOC, AMPD2, APRT, ARNT, ATP1A2, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1B2, ATP6V0A1, BAD, TSPO, CDA, COX8A, COX15, CTNS, DLG2, DLG3, DNMT1, DNMT3B, ENO2, GAPDH, HMGCR, HPRT1, IGF1, IMPDH1, IMPDH2, INS, LDHC, OGDH, P2RX7, PGAM1, PPP2R5D, PRKAA1, PRKAG1, PTGDR, SDHC, SNCA, STAT3, SULT1E1, SULT1A3, SULT1C2, SULT2B1, TAZ, UPP1, UQCRC1, UQCRC2, UQCRH, OGT, PAPSS1, SLC25A13 |
1477 | GO:0051051 | 0.02 | 1.59 | 22.97 | 32 | 98 | negative regulation of transport | ATF4, BARD1, BST2, CD36, PTK2B, GDI1, ICAM1, INSIG1, ITGAV, TONSL, PPM1B, PRKAA1, PRKD1, PTEN, RAC1, RANGAP1, SFRP5, SP100, STC1, TRIP6, NR1H2, VIP, AKAP1, PICALM, DYRK2, OGT, PEA15, TNFSF14, UNC119, ITGB1BP1, LITAF, BAG4 |
1478 | GO:0042176 | 0.00 | 1.59 | 57.19 | 79 | 242 | regulation of protein catabolic process | ARAF, ARNTL, BARD1, BUB1B, CAV3, CBLB, CCNB1, CDC20, CDC27, CENPF, CLU, CSNK1D, CSNK2A1, CSNK2A2, DUSP1, PTK2B, FYN, GPC3, GPLD1, GPX1, GRIN2A, NRG1, UBE2K, DNAJB2, IFNG, IL10, INS, SMAD3, SMAD7, ATXN3, OAZ1, OAZ2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, RAD23B, RB1, SKP1, SUMO3, SOX9, TNFRSF1B, TTK, UBB, UBE3A, SUMO1, VIP, WNT1, ZNF207, CUL3, CUL1, CDC23, CDC16, USP14, RGN, ZW10, PSMF1, BAG5, SEC22B, RNF14, DLGAP5, RNF40, PSME3, PSMD14 |
1479 | GO:1902679 | 0.00 | 1.59 | 152.20 | 207 | 644 | negative regulation of RNA biosynthetic process | ACVR2B, AEBP1, NR0B1, BIRC5, ARNTL, ASCL1, ASCL2, RERE, ATRX, BACH1, BCL3, PRDM1, BMI1, BMP4, KLF5, CAT, RUNX2, CD36, CDX2, CENPF, CHD4, CREB1, CRY2, DDX5, DNMT1, DNMT3B, DRD3, TSC22D3, E2F6, E4F1, EFNA1, EN1, EP300, ERF, ETV3, ETV6, FGFR3, GATA6, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, HBE1, HCLS1, HDGF, NRG1, HHEX, HIC1, HMGA1, FOXA2, HOXD8, HOXD9, HSF4, IFI16, IFNA2, IFNG, IGF1R, RBPJ, IRAK1, IRAK2, IRF1, ISL1, JARID2, JUN, JUND, LMO1, SMAD3, SMAD7, CIITA, TONSL, CNOT2, YBX1, ORC2, OVOL1, PA2G4, PAX3, PAX9, CHMP1A, PHF2, PIM1, PPID, PSMC3, PTGIS, PURA, RARA, RARB, RB1, REST, RFX3, RXRA, S100A1, SALL1, SATB1, XCL1, SET, SFPQ, SFRP5, SIM2, SIX3, SMARCA2, SMARCA4, SMARCE1, SNAI1, SNCA, SOX3, SOX9, SOX10, SOX11, SP100, SREBF1, SRF, SRY, TRIM21, STAT3, STAT6, TAF7, TAL1, TBL1X, TBP, NR2F1, NR2F2, KLF10, TP73, NR2C1, TSG101, TNFSF4, UBB, SUMO1, SCGB1A1, NR1H2, WFS1, WNT11, XRCC5, YY1, ZNF24, ZNF91, ZNF136, ZNF148, ZNF154, ZNF157, ZNF174, ZNF177, ZNF189, ZNF217, ZNF224, NRIP1, USP9X, KDM5C, HIST1H4I, FZD6, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, CUL3, KLF11, HAT1, TP63, EED, SAP30, HESX1, PER3, TAX1BP1, HIST1H3F, HIST1H2AG, TAF1B, TAF1A, RNF8, UBA3, USP2, RGN, CBFA2T2, AURKB, KLF4, COPS2, RECQL5, HAND1, ZNF254, CLOCK, KDM4A, ST18, ZEB2, NR1I3, NR1H4, NR1D2, CASP8AP2, NR2E3, ZBTB33, HDAC6, ZNF263, ZNF256, OLIG2, RAMP3 |
1480 | GO:0006461 | 0.00 | 1.58 | 84.31 | 116 | 365 | protein complex assembly | ACACB, ACADS, ACVRL1, ALAD, ANXA5, ANXA6, APAF1, BIRC3, BIRC5, ARG1, ASL, BAD, BLK, CAT, CCNB1, CD3G, ENTPD2, CD59, CDA, CHD4, CHRNB2, CHRNB4, COL1A1, COL6A1, COL6A2, CLDN3, CTH, CTNNA1, DNM1, DPYSL3, EPRS, GFAP, GJB1, GLRA1, GRIA1, HBA2, HBE1, HMGCR, HMGA1, HPRT1, HRG, HSF4, IGF1R, IL1RAP, ILK, IMPDH2, INS, IRAK1, KCNA1, KCNA3, KCNA4, KCNC2, KCND2, KCND3, KCNJ2, KCNS2, KCNS3, KPNA3, LIPC, OAT, OTX2, P2RX1, P2RX3, P2RX4, P2RX7, PAM, CHMP1A, PLN, PPID, PPP2R1A, PPP2R1B, PPP5C, PPP6C, PRKAA1, PEX5, RAD51, RPS19, RRM1, RRM2, RXRA, RXRG, TRAPPC2, SELP, SH3BGR, SHMT1, SHMT2, SLC9A1, SLC34A1, SLC22A1, SOD2, TRIM21, STXBP3, SYT1, TAF10, TP73, TRAF1, TSC1, ZNF148, CLPP, CUL3, OGT, IKBKAP, USO1, TP63, LIN7A, CLDN1, ZW10, REPS2, AURKB, ITGB1BP1, SLC9A3R1, KIF3B, NRXN1, EIF2AK3, SEC22B, GOSR2 |
1481 | GO:0060560 | 0.02 | 1.58 | 27.41 | 38 | 116 | developmental growth involved in morphogenesis | ABL1, APP, ARHGAP4, BMP4, BMPR2, DCC, DNM2, S1PR1, EFNA5, EMX1, CTTN, GOLGA4, NRG1, ILK, ITGB1, LIMK1, NRCAM, NTRK3, RNF6, SALL1, SEMA3F, SLC12A2, SOX9, SRF, SYT1, SYT4, TNR, WNT11, SEMA3B, RND2, USP9X, NRP2, NRP1, SLIT2, AATK, RIMS2, SEMA3E, SPRY1 |
1482 | GO:0051641 | 0.00 | 1.58 | 80.46 | 111 | 364 | cellular localization | ABCA1, ACACB, ACTN1, ACVR2B, AGTR1, ABCD1, ANXA3, APP, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, KIF1A, AXL, BGLAP, VPS51, CACNA1B, CD9, CDX2, CHAT, CLCN3, CLU, CNP, CPT1B, CPT2, CTGF, EIF4E, EPS15, EYA2, F7, F10, FTL, GAA, GAD1, GCGR, GLE1, GOLGB1, XCR1, HGF, HRG, IGF2, RBPJ, IL1RN, KCNJ10, KIF5A, KNG1, LAMP2, MYO1B, P2RX1, SERPINE1, PCSK5, PROC, PSAP, PTPRN, PTPRN2, RAB5B, RAF1, RANBP1, UPF1, RYR1, SORT1, S100A12, CCL21, SELP, SET, SRSF1, SRSF5, SRSF7, SLC1A6, SLC6A13, SLC8A3, SLC22A2, SPARC, HNF1A, TSC1, TUBA4A, TYRO3, UCP1, VEGFB, VIP, TRPV1, TUBA1A, SCG2, ANP32A, SYN3, PICALM, FZD4, EEA1, SLC25A12, SRSF9, PROZ, SEC22C, DGKI, NRXN3, COG1, VPS26A, CLINT1, SCRN1, DNAJC6, ZC3H11A, SMG7, SGSM2, RBM8A, GOLGA5, ATP9A, COL4A3BP, SLC25A13, SLC25A15, ABCC4 |
1483 | GO:0034220 | 0.00 | 1.58 | 123.32 | 168 | 528 | ion transmembrane transport | ABCA1, ACACB, ANXA5, ANXA6, AQP5, AQP6, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP4B, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, CACNA1A, CACNA1B, CACNB4, CASQ1, CASQ2, CAV3, CHRNB2, CHRNB4, CLCA1, CLCN3, CLCN6, CLCN7, CLCNKA, CLCNKB, CNGA1, COX6A1, COX6B1, COX7A1, COX7C, COX8A, COX15, CPT1B, CPT2, CRHBP, CYB5A, CYBA, DIAPH1, DRD3, TSC22D3, PTK2B, GABRA4, GABRA5, GABRE, GABRG1, GABRR1, GABRR2, GLRA1, GPM6A, XCR1, GRIA1, GRIA4, GRID1, GRID2, GRIN2A, HRC, HTR2C, ITGAV, ITPR1, KCNA1, KCNA3, KCNA4, KCND2, KCND3, KCNJ1, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN4, KCNS2, KCNS3, P2RX1, P2RX3, P2RX4, P2RX5, PDE4B, FXYD3, PLN, PRKCE, PRKD1, PTPN6, RAF1, REST, RHAG, RHCE, RHD, RYR1, SCN1A, SCN2A, SCN4B, SCN5A, SCN7A, SCN8A, SCNN1A, SCNN1B, SCNN1G, CCL21, SGK1, SLC1A6, SLC4A1, SLC6A6, SLC6A7, SLC7A1, SLC7A4, SLC8A3, SLC9A2, SLC9A3, SLC12A1, SLC12A2, SLC13A1, SLC20A1, SLC22A3, SLC22A2, SLC22A5, SPINK1, TRPC3, TRPC4, TRPC5, TRPM2, UBB, UQCRC1, UQCRH, VDAC2, TRPV1, SLC30A2, KCNAB1, SLC7A5, SLC25A12, RIPK1, SLC5A6, ATP6V0D1, SLC16A6, SLC16A5, KCNAB3, SLC9A3R1, SLC22A8, NRXN1, KCNK6, ATG5, SLC4A7, ATP6V1G1, PIEZO1, OXSR1, SLC12A6, HCN4, ABCC9, SGK2, SLC25A13, SLC25A15, SLC35B1, KCNMB2 |
1484 | GO:2000027 | 0.03 | 1.58 | 22.43 | 31 | 95 | regulation of organ morphogenesis | ABL1, ABL2, AGTR2, BAX, BMP4, BMPR1A, RUNX2, CHAD, EDNRA, GPC4, FGF3, FGF7, FZD2, B4GALT1, HGF, HOXC11, IFNG, RBPJ, ISL1, PAX9, PTN, RAC1, RXRA, RYK, SALL1, SOX9, WNT11, FZD6, FZD7, NUMB, SPRY1 |
1485 | GO:0009968 | 0.00 | 1.57 | 126.57 | 172 | 538 | negative regulation of signal transduction | ABL1, ABL2, ADAR, AGTR2, NR0B1, ARNTL, BAX, BCL2L1, PRDM1, BMP4, CALM3, CASQ2, CAV3, CBL, CBLB, CD44, CHAD, AP2S1, CLU, CRHBP, CRY2, CRYBA1, CTH, CTNNA1, CX3CR1, DCN, DUSP1, DUSP5, ECM1, EPHA2, CTTN, EPS15, FBLN1, FBN1, FGA, FYN, GCG, GP1BA, GPX1, GRB2, RAPGEF1, GRINA, HGF, NRG1, HHEX, HIC1, HMGCR, ONECUT1, HRG, HSPB1, ICAM1, IGF1, IGF1R, IGFBP3, IGFBP6, IHH, IL1A, IL1RN, IL10, ING2, INS, ISL1, ITGA1, ITGAV, ITGB1, ITPR1, LRPAP1, LTF, SMAD3, SMAD6, SMAD7, CNOT2, YBX1, OPA1, P2RX7, SERPINE1, PPM1B, PPP2CB, PPP2R1A, PRKAA1, PRKCQ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTPN6, PTPRE, PTPRJ, PTPRR, RAF1, RASA2, RFNG, RGS10, RPS6KB1, CX3CL1, SEC14L1, SFRP5, SIX3, SMARCA4, SNAI1, SOD2, SOX9, SOX10, SPINK1, ADAM17, TP73, TPT1, TRIP6, TSC1, TYRO3, UBB, NR1H2, VDAC2, WFS1, WNT1, WNT11, SCG2, FZD6, CUL3, RGS20, NUMB, PEA15, RIPK1, TNFSF14, DLK1, NRP1, ARHGEF7, SOCS3, LATS1, IL1RL1, ARHGEF2, ITGB1BP1, SOCS6, KLF4, SLIT2, SLC9A3R1, ZFYVE9, GSTO1, ONECUT2, PSMF1, LITAF, BAG5, CLOCK, ADAMTSL2, EIF4A3, RB1CC1, NR1H4, RBX1, PDCD6, RANBP9, IL18BP, TRAP1, G3BP1, RASA4, PSME3, PSMD14, SPRY1, STAM2 |
1486 | GO:0043436 | 0.04 | 1.57 | 18.75 | 26 | 82 | oxoacid metabolic process | ANGPT1, EXT2, EXTL1, EXTL3, GPC4, GALNS, B4GALT1, GPC3, HEXA, HEXB, IDS, OMD, SDC4, SULT1E1, SULT1A3, SULT1C2, SULT2B1, B4GALT4, B4GALT3, PAPSS1, B4GALT6, CHST3, MINPP1, SDC3, SPOCK2, HS3ST3B1 |
1487 | GO:0015749 | 0.03 | 1.57 | 22.45 | 31 | 95 | monosaccharide transport | C3, EDNRA, G6PC, GPC3, FFAR3, NRG1, IGF1, INS, NUP98, PRKAA1, PRKCI, RANBP2, RPS6KB1, RTN2, SORT1, SLC2A3, SLC2A4, SLC2A5, SLC5A2, STXBP3, HNF1A, TSC1, VIL1, NUP214, AAAS, CLTCL1, PIK3R3, PEA15, NUP155, NUP93, C2CD5 |
1488 | GO:0010608 | 0.00 | 1.57 | 66.41 | 91 | 281 | posttranscriptional regulation of gene expression | ADAR, ANG, APP, ATF4, BCL3, ZFP36L2, CD28, CDK4, CIRBP, DAPK3, DAZ1, DDX1, DDX6, DKC1, EIF2B1, EIF4A1, EIF4E, EIF4G2, EIF5, EIF5A, ELAVL1, EPRS, PTK2B, GAPDH, GRB7, HNRNPC, HSPB1, IGF1, EIF3E, CAPRIN1, SMAD1, SMAD3, CNOT2, YBX1, PA2G4, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTAFR, PURA, RAN, RARA, RBM4, UPF1, RPL38, RPS3, RPS6KA1, RPS6KB1, RPS6KB2, RXRA, S100A9, SET, SRP9, TNFRSF1B, TSC1, UBB, SCGB1A1, VIP, EIF4H, YWHAZ, NUP214, ANP32A, KHSRP, EIF4EBP3, EIF3G, EIF4G3, EIF2B3, EIF2B2, EIF2AK3, PSMF1, EIF5B, EIF4A3, RBM8A, TRAP1, PSME3, EIF1, PSMD14 |
1489 | GO:0018193 | 0.00 | 1.57 | 144.10 | 195 | 615 | peptidyl-amino acid modification | ABL1, ABL2, ACTL6A, ADH5, ALK, BIRC5, APLP2, APP, ARCN1, ARNT, AXL, BCR, BGLAP, BLK, BMI1, BRCA2, BTK, CALM3, CANX, CD3E, CD4, CD36, CD59, CHEK1, CLK3, COPA, CSF1R, CSPG4, CTF1, CTH, DAD1, ACE, DYNC1H1, DNMT1, DNMT3B, PHC2, EFNA1, EFNA5, EGR2, EPHA2, EIF5A, EP300, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, ERCC6, EZH1, F2, F2R, F7, F10, PTK2B, EFEMP1, FGF7, FGFR3, FGR, FKBP3, FKBP5, FLT1, FLT3, FLT4, FUT8, FYN, GAPDH, KAT2A, B4GALT1, GMDS, GOLGA2, GOLGB1, GRIA1, HIST1H1B, HGF, NRG1, UBE2K, HMBS, HNRNPC, HPX, HRG, ICAM1, IGF1, IGF1R, IGF2, IL12B, IL12RB2, IL13, IL18, INS, INSRR, ISL1, ITGA5, ITGB1, JARID2, KDR, KIT, MGAT2, MGAT3, KITLG, MAP3K11, NUP98, P4HA1, PCNA, PPIB, PPID, PPP2R1A, PPP6C, PRKCSH, PROC, PTK2, PTPN6, RAB1A, RAB3B, RAB6A, RAD21, RANBP2, RANGAP1, RAP2B, RYK, S100A8, S100A9, TRAPPC2, SET, SETMAR, SHC1, SUMO3, SP100, UAP1, SPINK1, ADAM17, TAF7, TAF10, TNFRSF1A, TOP1, TOP2A, TOP2B, TTK, TYRO3, SUMO1, KDM6A, VEGFB, VTN, PRDM2, TUSC3, NUP214, AAAS, SMC1A, GFI1B, DYRK2, TPST2, TPST1, FKBP6, HAT1, STK16, RUVBL1, USO1, DYNLL1, B4GALT4, B4GALT3, EED, TNFRSF18, DYRK4, DPM2, NRP1, PROZ, HERC2, P4HA2, TNFSF18, BAZ1B, UNC119, SMC3, DYRK1B, ARHGEF2, COPB2, GTF3C4, B4GALT6, COG1, ATG5, GOSR1, SEC22B, GOSR2, CLOCK, AATK, NUP155, TTLL4, KDM4A, NUP93, SETD1A, OXSR1, NR1H4, HDAC6, GNE, UBA2, SAE1, ABI2 |
1490 | GO:0048608 | 0.04 | 1.57 | 19.54 | 27 | 84 | reproductive structure development | NR0B1, AXL, BOK, BRCA2, COL9A3, GATA6, GDF9, IDH1, PGR, PRKACG, PTPRN, RRM1, SALL1, SRD5A1, SRY, STAT5B, TSPY1, TYRO3, NRIP1, FZD4, AKR1C3, ADAM15, EIF2S2, SLIT2, BCL2L11, AKAP9, IRX5 |
1491 | GO:0001558 | 0.01 | 1.57 | 32.67 | 45 | 139 | regulation of cell growth | ABL1, ACVRL1, AGTR1, AGTR2, ARHGAP4, FXYD2, BST2, CAV3, CDA, CDK11B, CDKN1A, CTGF, DCC, DNM2, CTTN, GDF9, HRG, IGFBP3, IGFBP6, SMAD3, NRCAM, PPP2R1A, PRKCQ, PTPRJ, RNF6, SEMA3F, SIPA1, SMARCA2, SMARCA4, SPOCK1, TNR, TSG101, WNT11, SEMA3B, BAP1, BLZF1, ADAM15, WISP3, CTDP1, SLIT2, BCAR1, AATK, SEMA3E, ARHGEF11, SGK2 |
1492 | GO:0007266 | 0.04 | 1.57 | 20.32 | 28 | 86 | Rho protein signal transduction | ABCA1, ABL2, AGTR1, ARHGAP4, ARHGAP6, ARHGDIB, BCR, CHUK, LPAR1, EDNRA, F2R, FGD1, ITGB1, LIMK1, RAC1, RAF1, SOS2, VAV1, ARHGEF5, CUL3, CTNNAL1, ARHGEF7, ARHGEF1, ARHGEF2, GPR55, ARHGAP29, ARHGEF11, FARP1 |
1493 | GO:0090066 | 0.00 | 1.57 | 45.17 | 62 | 193 | regulation of anatomical structure size | ABL1, ADD1, ARF1, ARHGAP4, ATP2B2, BBS4, CAPG, CAV3, CDK4, CLCN3, CLCN6, CLNS1A, CREB1, DCC, DNM2, EFNA5, CTTN, PTK2B, GOLGA4, GRB2, HCLS1, NRG1, ILK, KCNN4, LIMK1, NRCAM, NTRK3, P2RX7, PFN2, PRKCE, PTEN, RAB3B, RAB5A, RAC1, RNF6, CCL21, SEMA3F, SRF, CNTN2, TNR, TP73, TSC1, VAV1, VIL1, SEMA3B, RND2, OGT, PEX11A, NRP1, LATS1, SLIT2, SLC9A3R1, PICK1, BAG4, AATK, SEMA3E, RB1CC1, ARPC5, ARPC1B, ACTR2, ARPC2, ABI2 |
1494 | GO:1904950 | 0.02 | 1.56 | 26.23 | 36 | 111 | negative regulation of establishment of protein localization | ANGPT1, ANXA1, ANXA5, BARD1, BCL2L1, CD36, DRD3, F2R, FBLN1, GDI1, GHSR, HMGCR, IFNA2, IL10, INS, KCNJ11, TONSL, PPM1B, RANGAP1, REST, CX3CL1, SFRP5, SP100, SREBF1, TRIP6, TNFSF4, AKAP1, DYRK2, OGT, TNFSF14, ITGB1BP1, SLC9A3R1, LITAF, TMEM59, BAG4, NR1H4 |
1495 | GO:0050707 | 0.05 | 1.56 | 18.20 | 25 | 77 | regulation of cytokine secretion | ABL1, ABL2, AGTR2, ALOX15B, ANGPT1, ANXA1, CASP5, CD58, CRP, CSF1R, F2R, FBLN1, FGR, IFNA2, IFNG, IL1A, IL10, INS, P2RX7, PAEP, CX3CL1, TNFSF4, IL1RL1, ATG5, NR1H4 |
1496 | GO:0001818 | 0.03 | 1.56 | 24.05 | 33 | 102 | negative regulation of cytokine production | AXL, BTK, TSPO, CRYBA1, FBLN1, GATA6, GHSR, IFNG, IL12B, IL13, IDO1, INHA, LTF, PCBP2, PPM1B, PRG2, RAC1, RARA, CX3CL1, SFTPD, TNFSF4, UBB, UBA7, SCGB1A1, WNT11, TRIM25, TAX1BP1, RPS6KA4, IL1RL1, ATG5, NR1H4, NUTF2, PRG4 |
1497 | GO:0006839 | 0.01 | 1.55 | 37.34 | 51 | 158 | mitochondrial transport | ACACB, ACTL6A, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, BAD, BAX, BCL2L1, BNIP3L, TSPO, CAMK2A, CNP, CPT1B, CPT2, CSNK2A2, CTSK, EYA2, KAT2A, GFER, GPR26, NRG1, HNMT, HSPA4, HSPA9, RAC2, RNASE2, SLC8A3, SLC9A1, SREBF1, STAT3, UBE2L3, UCP1, YWHAZ, ZBTB17, FZD5, BAP1, SLC25A12, RUVBL1, DYNLL1, CDKL2, BAG4, ATG13, TOMM20, FAM20B, BCL2L11, SAE1, SLC25A13, SLC25A15 |
1498 | GO:0007389 | 0.00 | 1.55 | 44.00 | 60 | 187 | pattern specification process | ACVR2B, ALX3, ASCL1, BAX, BBS4, BMI1, BMP4, BMPR1A, BMPR2, CDX2, CRKL, EDNRA, EGR2, EMX1, EMX2, EN1, EP300, EVX1, FGF3, GATA4, KAT2A, GPC3, HHEX, HOXC10, HOXC11, HOXD9, HOXD10, HOXD12, RBPJ, ISL1, NTF4, OTX1, PAX3, PCDH8, PCSK5, PRKACB, PSKH1, RFNG, RFX3, SIX3, SMARCD3, SNAI1, SRF, STC1, NR2F1, NR2F2, TULP3, XRCC2, YY1, ZIC1, RGS20, TP63, CHRD, KIF3B, HAND1, SEMA3E, IFT140, ZEB2, ATP6AP2, SPRY1 |
1499 | GO:1901657 | 0.00 | 1.55 | 47.74 | 65 | 202 | glycosyl compound metabolic process | ACACB, ACPP, ADSS, AHCY, AK1, AK2, ALDOC, AMPD2, APRT, ARNT, ATP1A2, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V1B2, ATP6V0A1, BAD, TSPO, CDA, AKR1C4, COX8A, COX15, CTNS, DLG2, DLG3, DNMT1, DNMT3B, TYMP, ENO2, GAPDH, HMGCR, HPRT1, IGF1, IMPDH1, IMPDH2, INS, LDHC, OGDH, P2RX7, PGAM1, PPP2R5D, PRKAA1, PRKAG1, PTGDR, SDHC, SLC34A1, SNCA, STAT3, SULT1E1, SULT1A3, SULT1C2, SULT2B1, TAZ, TYMS, UPP1, UQCRC1, UQCRC2, UQCRH, OGT, AKR1C3, PAPSS1, SLC25A13 |
1500 | GO:0048519 | 0.00 | 1.55 | 280.75 | 367 | 1280 | negative regulation of biological process | ABCA1, ACACB, ACTN1, ACVR2B, ADAM10, ADD1, ADRA1B, AEBP1, AK1, ALB, ANG, ANXA3, BIRC3, XIAP, BIRC5, APLP2, ARAF, ARHGAP6, ARL2, ASS1, RERE, ATR, ATRX, BACH1, BAD, BCL2A1, BLK, BMI1, BNIP3L, DST, ZFP36L2, KLF9, KLF5, BUB1B, C3, CACNA1A, CAPG, CASQ1, CAT, CCNB1, CCNC, CCNF, CD9, CD28, TNFRSF8, CDA, CDC20, CDC27, CDH1, CDK2, CDK4, CDKN1A, CDX2, CENPF, CHD4, CHEK1, CIRBP, CNN3, COL1A1, COL6A3, COMP, CREB1, CSF1R, CSNK2A1, CSNK2A2, CST6, CTGF, CTSH, DAD1, DAPK3, BRINP1, ACE, DDX5, DFFA, DIAPH1, DLG2, DLG3, DNMT1, DNMT3B, DPP4, E2F6, E4F1, S1PR1, EDNRA, EGR3, EIF4G2, SERPINB1, EN1, EP300, EPRS, ERCC3, ERCC4, ERF, ETV3, ETV6, FGF4, FLOT2, FLT4, GABRA5, GALR1, GAPDH, GAS1, GAS2, GATA4, GDF9, B4GALT1, GNAQ, GNAT1, GOLGA2, GPLD1, XCR1, GRB7, GRIN2A, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, HBE1, HCLS1, HDGF, HMGA1, NR4A1, HNRNPC, HOXD8, HOXD9, HPGD, HRC, HSF4, DNAJB2, HSPA9, HTR2C, IFIT3, IFNW1, IL18, INPPL1, EIF3E, IRAK1, IRAK2, ITGA5, ITIH1, ITIH4, JARID2, JUND, KCNJ1, KDR, KISS1, KIT, KIF25, IPO5, LIMK1, LMO1, CAPRIN1, SMAD1, MGMT, PPP1R12A, NUBP1, NTF4, NTRK2, NUP98, ORC2, OVOL1, PA2G4, PAX3, PAX9, SERPINA5, CHMP1A, PCP4, PDK4, PGR, PHF2, SERPINA4, SERPINB5, SERPINB13, SERPINI2, PIM1, PPID, PPP1R8, PPP5C, PRCC, PRKAG1, PRKAR1B, PRKAR2A, PRKAR2B, PRKCI, PRPSAP1, PTPRN2, PURA, PEX5, PZP, RAG1, RAN, RANBP2, RBM4, RENBP, UPF1, RFX3, RHEB, RPA2, RPL24, RPS3A, RPS6KA1, RXRA, RYR1, RYR2, S100A1, SORT1, S100A11, SATB1, SET, SETMAR, SFPQ, SRSF7, SFSWAP, SGK1, STIL, SIM2, SIPA1, SLC9A1, SMARCA2, SMARCE1, SNCB, SNRNP70, SRP9, SRY, STRN, SUPV3L1, TAF7, TAL1, TBCD, SERPINA7, TBL1X, TBP, NR2F1, KLF10, TNNI3, TOP2A, TOP2B, NR2C1, HSP90B1, TRAF2, TRPC1, TSN, TSG101, TTF1, TTK, UNG, USP4, VEGFB, VIL1, VIPR2, TRPV1, XRCC2, XRCC5, YY1, YWHAZ, ZNF16, ZNF24, ZNF91, ZNF136, ZNF148, ZBTB17, ZNF154, ZNF157, ZNF174, ZNF177, RNF112, ZNF189, ZNF207, ZNF217, ZNF224, FZD5, AIMP2, NUP214, FOSL1, AAAS, NRIP1, USP9X, KDM5C, SMC1A, BAP1, FZD4, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, SOX14, UXT, ZNF282, CUL2, CUL1, KLF11, SMARCA5, FKBP6, PPM1D, IKBKG, HAT1, GAS7, API5, EIF4EBP3, AKR1C3, DYNLL1, SRSF9, CDC23, SERPINB7, TRADD, EED, CRADD, TNFSF10, RIPK2, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, SAP30, HESX1, WISP3, PER3, CDC16, EIF2B3, HIST1H3F, HIST1H2AG, TAF1B, TAF1A, RNF8, UBA3, SMC3, ZW10, AURKB, COPS2, RECQL5, HAND1, AKAP6, BAG3, ZNF254, APBA3, CXCL14, GABBR2, MAD2L1BP, NUP155, KDM4A, NUP93, DHX34, ST18, PHACTR2, RNF40, ZEB2, DLEC1, NR1I3, NR1D2, FGFBP1, CASP8AP2, NR2E3, ZBTB33, HDAC6, RAD50, ZNF263, FARP1, WASF2, ZNF256, DHRS2, CTDSPL, RAMP3 |
1501 | GO:0016054 | 0.01 | 1.55 | 34.50 | 47 | 146 | organic acid catabolic process | ABAT, ACACB, ACADM, ACADS, AHCY, ABCD1, ARG1, ASL, AUH, BCKDHA, CDO1, CNR1, CPT1B, CPT2, CRAT, CTH, DBT, ECH1, FAAH, GAD1, GLDC, GLUD1, GOT2, GPT, GSTZ1, HNMT, IDUA, IDO1, IVD, LIPE, OAT, OGDH, PAH, PEX7, PEX13, ABCD3, QDPR, RENBP, SHMT1, SORD, SUOX, TAT, ACOX3, DDO, ALDH4A1, KYNU, XYLB |
1502 | GO:2000026 | 0.03 | 1.55 | 22.59 | 31 | 101 | regulation of multicellular organismal development | ACACB, ACVR2B, ALOX15B, ARHGDIB, BMP1, BRCA2, COL1A1, CTGF, DMBT1, S1PR1, GDF9, GNAQ, GPX1, IL13, SMAD1, SMAD7, OMD, P2RX7, PRKX, PROC, RFX3, SFRP5, SRY, TNFRSF1A, FGF23, TP63, PTCH2, TRADD, RGN, CLOCK, ZEB2 |
1503 | GO:0045934 | 0.00 | 1.55 | 168.59 | 225 | 715 | negative regulation of nucleobase-containing compound metabolic process | ACVR2B, ACVRL1, AEBP1, NR0B1, BIRC5, ARNTL, ASCL1, ASCL2, RERE, ATR, ATRX, BACH1, BARD1, BCL3, PRDM1, BMI1, BMP4, BMPR2, BRCA2, KLF5, CAT, RUNX2, CD36, CDX2, CENPF, CHD4, CREB1, CRY2, DDX5, DFFA, DNMT1, DNMT3B, TSC22D3, DUSP1, E2F6, E4F1, EFNA1, EN1, EP300, ERCC4, ERF, ETV3, ETV6, FGFR3, GATA6, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, HBE1, HCLS1, HDGF, NRG1, HHEX, HIC1, HMGA1, FOXA2, HNRNPC, HOXD8, HOXD9, HSF4, IFI16, IFNA2, IFNG, IGF1R, RBPJ, IRAK1, IRAK2, IRF1, ISL1, JARID2, JUN, JUND, KCNK2, LMO1, SMAD3, SMAD7, CIITA, TONSL, CNOT2, YBX1, ORC2, OVOL1, PA2G4, PAX3, PAX9, CHMP1A, PHF2, PIM1, PPID, PSMC3, PTGIS, PURA, RARA, RARB, RB1, REST, RFX3, RPS3, RXRA, S100A1, S100A11, SALL1, SATB1, XCL1, SET, SFPQ, SFRP5, SRSF7, SFSWAP, SIM2, SIX3, SMARCA2, SMARCA4, SMARCE1, SNAI1, SOX3, SOX9, SOX10, SOX11, SP100, SREBF1, SRF, SRY, TRIM21, STAT6, TAF7, TAL1, TBL1X, TBP, NR2F1, NR2F2, KLF10, TP73, NR2C1, TSG101, TTF1, TNFSF4, UBB, SUMO1, SCGB1A1, NR1H2, WFS1, WNT11, XRCC5, YY1, ZNF24, ZNF91, ZNF136, ZNF148, ZNF154, ZNF157, ZNF174, ZNF177, ZNF189, ZNF217, ZNF224, NRIP1, USP9X, KDM5C, SMC1A, HIST1H4I, FZD6, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, CUL3, KLF11, HAT1, TP63, SRSF9, EED, SAP30, HESX1, PER3, TAX1BP1, HIST1H3F, HIST1H2AG, TAF1B, TAF1A, RNF8, UBA3, USP2, RGN, SMC3, CBFA2T2, AURKB, KLF4, COPS2, RECQL5, HAND1, ZNF254, CLOCK, KDM4A, DHX34, ST18, RNF40, ZEB2, NR1I3, NR1H4, NR1D2, CASP8AP2, NR2E3, ZBTB33, HDAC6, RAD50, ZNF263, ZNF256, OLIG2, RAMP3 |
1504 | GO:0032880 | 0.00 | 1.54 | 125.96 | 169 | 533 | regulation of protein localization | ABAT, ABL1, ABL2, ACTL6A, AGTR2, ALOX15B, ANG, ANGPT1, ANXA1, ANXA5, ARF1, ARL2, ARNTL, BAD, BARD1, BCL2L1, BCL3, BLK, BMP4, BMPR1A, BNIP3L, CACNA1A, CASP5, CAV3, CCNB1, CD36, CD58, CDH1, CDKN1A, CHRM1, CHRM3, CNR1, CRH, CRP, CSF1R, CSNK2A2, CTSK, DKC1, DRD3, EDA, EFNA5, EPHA2, EPHA5, F2R, FBLN1, FGA, FGR, FYN, GCG, KAT2A, GDI1, GHSR, GLUD1, GNAQ, GNAS, GPLD1, GPR26, FFAR1, HCLS1, NRG1, HMGCR, FOXA2, HNMT, DNAJB2, IFNA2, IFNG, IGF1, IL1A, IL10, IL12B, IL13, IL18, INS, ISL1, ITGB1, ITPR1, KCNC2, KCNJ11, KCNN4, KCNS3, KPNA1, IPO5, LLGL2, SMAD3, TONSL, OAZ1, OAZ2, OXCT1, P2RX7, PAEP, PRDX1, PAM, PCM1, PPID, PPM1B, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRKCI, PRKCQ, PTN, RAC2, RANGAP1, RB1, REST, RFX3, RNASE2, CX3CL1, SFRP5, SLC9A1, SNAP25, SP100, SREBF1, SYT5, TRAF2, TRIP6, TRPM2, TSG101, TNFSF4, UBE2L3, SUMO1, NR1H2, VIL1, VIP, YWHAZ, ZIC1, ZBTB17, FZD5, ARHGEF5, AKAP1, PICALM, BAP1, FZD7, DYRK2, OGT, RGS20, RUVBL1, NUMB, DYNLL1, VAMP8, TNFSF14, CDKL2, SYT7, IL1RL1, ITGB1BP1, HMGN3, RAB9A, SLC9A3R1, NRXN1, EIF2AK3, AKAP6, ATG5, LITAF, TMEM59, BAG4, CLOCK, ATG13, C2CD5, FAM20B, NR1H4, HDAC6, BCL2L11, SAE1, NUTF2, RAMP3 |
1505 | GO:0045664 | 0.01 | 1.54 | 42.68 | 58 | 182 | regulation of neuron differentiation | ABL1, ABL2, ARF1, BMP4, BMPR2, CACNA1A, CDC20, CHN1, CHRNB2, CNR1, CRX, BRINP1, DNM2, DNMT3B, EFNA5, CTTN, EPHB3, ETV5, PTK2B, FYN, GOLGA4, RAPGEF1, GRID2, HGF, NRG1, IFNG, ILK, LIMK1, CAPRIN1, NRCAM, NTF4, NTRK2, NTRK3, OPA1, P2RY2, PALM, PCP4, SERPINF1, PRKCI, PRKD1, PTN, RAC1, RAC3, RAP2A, RARA, RARB, SALL1, SGK1, SNAP25, SOX11, SRF, SYT1, SYT4, RNF112, RND2, KLF4, RIMS2, CUL7 |
1506 | GO:0044248 | 0.03 | 1.54 | 22.71 | 31 | 100 | cellular catabolic process | ADH5, BHMT, DAGLA, CAPN1, TPP1, VCAN, CSPG4, CYP3A4, ACE, DPEP1, ESD, FABP2, FABP7, GALC, GALNS, GM2A, HBA2, HEXA, HEXB, IDS, LIPC, LTA4H, OMD, OXCT1, PRDX1, PRKACB, PRKACG, FGF23, AKR1C3, LIPG, GSTO1 |
1507 | GO:0090092 | 0.03 | 1.54 | 25.76 | 35 | 109 | regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | ABL1, ACVR2B, ACVRL1, XIAP, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, CAV3, DNM2, FBN1, GATA4, GATA6, GDF9, GPC3, ONECUT1, RBPJ, ILK, ING2, INHA, SMAD3, SMAD6, SMAD7, SOX11, ADAM17, TTK, UBB, WNT1, CHRD, ZFYVE9, ONECUT2, GDF15, ADAMTSL2 |
1508 | GO:0009165 | 0.04 | 1.53 | 21.34 | 29 | 91 | nucleotide biosynthetic process | ACACB, ADSS, AK1, AK2, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, DHFR, GUCY2C, GUCY2F, GUCY2D, HTR2C, IMPDH1, IMPDH2, LDHC, PFAS, PRPSAP1, RRM1, RRM2, SHMT1, TYMS, KYNU, PAPSS1, TBPL1, SLC25A13 |
1509 | GO:0031334 | 0.04 | 1.53 | 22.87 | 31 | 97 | positive regulation of protein complex assembly | ARF1, ARL2, BAX, CAV3, CD36, CTTN, PTK2B, GRB2, ICAM1, PFN2, PRKCE, RAC1, RPS3, CLIP1, CCL21, FSCN1, TAL1, SUMO1, VIL1, ARHGEF5, HRK, PICK1, BAG4, PIEZO1, HDAC6, BCL2L11, ARPC5, ARPC1B, ACTR2, ARPC2, ABI2 |
1510 | GO:0080090 | 0.00 | 1.53 | 709.22 | 866 | 3036 | regulation of primary metabolic process | ABAT, ABCA1, ABCA2, ABL1, ABL2, ACTL6A, ACTN1, ACVR2B, ACVRL1, ADAR, AEBP1, AGTR1, AGTR2, NR0B1, ALK, ALX3, ANG, ANGPT1, ANXA1, ANXA3, APAF1, BIRC3, XIAP, BIRC5, APLP2, APOH, APP, ARAF, ARF1, PHOX2A, ARNTL, ARR3, ASCL1, ASCL2, ATF4, RERE, ATP1A1, ATP6AP1, ATR, ATRX, AVPR2, BACH1, BARD1, BAX, BBS4, BCL3, PRDM1, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, BOK, BRCA2, BRDT, ZFP36L2, BST2, KLF9, KLF5, BTF3, BTK, BUB1B, TSPO, C3, C7, CALM3, CAMK2A, CASP9, CAT, CAV3, RUNX2, CBL, CBLB, CCNB1, CCNC, CCNE1, CCNT2, CD3D, CD3E, CD4, CD28, CD86, TNFRSF8, TNFSF8, CD36, CD44, CD59, CDA, CDK11B, CDC20, CDC25A, CDC25C, CDC27, CDH1, CDK2, CDK4, CDK8, CDKN1A, CDX2, CEBPE, CENPB, CENPE, CENPF, CHAD, CHD2, CHD4, CHEK1, CHRNB2, CHUK, CIRBP, CKS1B, CLU, CLK1, CLK3, CNR1, COL1A1, COL4A3, COL6A3, CREB1, CRH, CRKL, CRX, CRY2, CRYBA1, CSF1R, CSF2RB, CSNK1D, CSNK2A1, CSNK2A2, CSPG4, CST6, CTF1, CTGF, CTH, CTNND2, CTSH, DAPK3, DAZ1, DCN, ACE, DDX1, DDX5, DDX6, DFFA, DHCR7, DHFR, DKC1, DLG2, DLG3, DLX5, DNM2, DNMT1, DNMT3B, DPEP1, DRD3, DRD5, ARID3A, RCAN1, TSC22D3, DUSP1, DUSP5, E2F6, E4F1, EBF1, ECM1, EDA, S1PR1, LPAR1, EDNRA, EFNA1, EFNA5, EGR2, EGR3, EGR4, EIF2B1, EPHA2, EIF4A1, EIF4E, EIF4G2, EIF5, EIF5A, SERPINB1, ELAVL2, ELAVL1, ELK1, EMP2, EMX1, EMX2, EN1, EP300, EPHA5, EPHA8, EPHB1, EPRS, EYA4, ERCC3, ERCC4, ERCC6, ERF, ERG, ESRRG, ETS1, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA2, EZH1, F2, F2R, F3, FBLN1, FBN1, EFEMP1, FGA, FGF3, FGF4, FGF7, FGFR3, FGR, FLOT2, FLT1, FLT3, FLT3LG, FLT4, AFF2, FPR1, FSHB, FSHR, NR5A2, FYN, FZD2, GALR1, GAPDH, GAS1, GATA4, GATA6, GDF9, GFAP, GHRHR, GHSR, GPC3, GNAQ, GNAS, GNG3, GP1BA, GPX1, GRB2, GRB7, RAPGEF1, GRIN2A, GRM1, GSC2, GTF2I, GTF3A, BRF1, GUCA1A, GUCA2A, GUCA2B, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, HBE1, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIP1, UBE2K, HIVEP2, HLF, HMGN1, HMGCR, HMGA1, NR4A1, HMX2, HNF4G, ONECUT1, HNRNPC, HOXC10, HOXC11, HOXD8, HOXD9, HOXD10, HOXD12, HPRT1, HPX, HRC, HRG, HSF4, DNAJB2, HSPB1, HTR2C, ICAM1, IDH1, IFI16, SP110, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1R, RBPJ, IHH, IL1A, IL2RA, IL10, IL12B, IL13, IL18, ILK, ING2, INHA, INSIG1, EIF3E, IRAK1, IRAK2, IRF1, IRF5, ISL1, ITGA1, ITGA5, ITGAV, ITGB1, ITIH1, ITIH4, JARID2, JUN, JUND, KCNK2, KDR, KISS1, KIT, KLKB1, KNG1, KPNA1, KPNA2, LIMK1, LMO1, LTF, CAPRIN1, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MARK3, MAZ, MEOX2, KITLG, MGMT, CIITA, ATXN3, MAP3K11, AFF1, FOXO4, PPP1R12A, TONSL, CNOT2, YBX1, NTRK2, NTRK3, NVL, OAS3, ORC1, ORC2, OTX1, OTX2, OVOL1, P2RX1, P2RY11, PA2G4, PRDX1, SERPINE1, PALM, PAM, PAX3, PAX9, SERPINA5, PCK1, PCNA, PCOLCE, CHMP1A, PCP4, PDE8A, SERPINF1, CFP, PFN2, PGR, PHF2, SERPINA4, SERPINB5, SERPINB9, SERPINB13, SERPINI2, PIM1, PPID, PPP1R8, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PPP4C, PPP5C, PRG2, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCI, PRKD1, PRKCQ, PSAP, PTEN, PTGIS, PTK2, PTPN6, PTPRA, PTPRJ, PTPRR, PURA, PZP, RAB1A, RAC1, RAC2, RAD21, RAD23B, RAD51, RAF1, RAG1, RAN, RAP2A, RAP2B, RARA, RARB, RASA2, RB1, RBBP6, RBL2, RBM4, RCVRN, RENBP, UPF1, DPF2, REST, RFX1, RFX3, RFXAP, RLF, RNF6, RPA2, RPL38, RPS3, RPS6KA1, RPS6KB1, RPS6KB2, RRM2, RXRA, RXRG, RYK, RYR2, S100A1, S100A7, S100A8, S100A9, S100A11, S100A12, SALL1, SATB1, SERPINB4, CCL21, CCL22, CCL25, XCL1, CX3CL1, SDC4, TRAPPC2, SET, SETMAR, SFPQ, SFRP5, SRSF7, SFSWAP, SFTPD, SGK1, SHC1, STIL, SIM2, SIX3, SKP1, SLC9A1, SLPI, SMARCA1, SMARCA2, SMARCA4, SMARCD3, SMARCE1, SUMO3, SNAI1, SNAPC3, SNRNP70, SOD2, SOX3, SOX9, SOX10, SOX11, SP1, SP100, SPIB, SPINK1, SPOCK1, SREBF1, SRF, SRP9, SRPK2, SRY, TRIM21, SSRP1, STAT2, STAT4, STAT5B, STAT6, STK10, STYX, SUPV3L1, XCL2, ADAM17, TACR3, TAF4B, TAF7, TAF10, TAL1, CNTN2, SERPINA7, TBL1X, TBP, HNF1A, ZNF354A, NR2F1, NR2F2, KLF10, TMPO, CLEC3B, TNFRSF1A, TNFRSF1B, TNNI2, TOP2A, TP73, TPD52L1, NR2C1, NR2C2, HSP90B1, TRAF1, TRAF2, TRIP6, TSC1, TSG101, TTF1, TTK, TULP3, TNFSF4, TYMS, UBB, UBE2D2, UBE2L3, UBE3A, SUMO1, UCP1, SCGB1A1, UNG, USP4, NR1H2, USF1, UVRAG, VAV1, VEGFB, VIL1, VIP, VIPR2, VTN, EIF4H, WFS1, WNT1, WNT11, XRCC5, YY1, ZFP37, ZFPL1, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF91, ZNF99, ZNF124, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZXDA, PRDM2, FZD5, AIMP2, ARHGEF5, PDHX, FOSL1, FGF23, CDK2AP1, ANP32A, AKAP1, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, SMC1A, USP9Y, HIST1H4I, PICALM, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, BCAR3, ZNF282, NSMAF, CUL4A, CUL3, CUL2, CUL1, KLF11, SMARCA5, PIK3R3, IKBKG, IKBKAP, HAT1, GAS7, PIR, BLZF1, CDC14B, KHSRP, STK16, RGS20, RUVBL1, KLF7, TP63, EIF4EBP3, AKR1C3, CHRD, PDE5A, DYNLL1, EIF3G, EIF4G3, PEA15, SRSF9, CDC23, SERPINB7, TRADD, EED, RIPK1, CRADD, TNFSF14, TNFSF10, RIPK2, TNFRSF18, TNFRSF10B, TNFRSF10A, SAP30, HESX1, NRP1, PER3, CDC16, TAX1BP1, EIF2B3, EIF2B2, BUD31, PHOX2B, HIST1H3F, HIST1H2AG, RPS6KA4, TNFSF18, TAF1B, TAF1A, SOCS3, RNF8, BAZ1B, UBA3, DIRAS3, UNC119, USP14, USP2, LATS1, PDLIM1, SMC3, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, ZW10, AURKB, VAPB, CCPG1, ITGB1BP1, GPR55, SOCS6, ZNF235, KLF4, COPS2, TRIP11, HMGN3, SLIT2, SLC9A3R1, LIPG, RECQL5, ZRANB2, HAND1, ZNF264, EIF2AK3, FHL5, IL27RA, AKAP6, ATG5, ONECUT2, LITAF, GDF15, TBPL1, BAG5, BAG4, ZNF254, NRG2, SEC22B, GTPBP1, GABBR2, CLOCK, SOX13, RBM39, AKAP12, RNF14, TRAF4, GUCA1C, ZNF516, EIF5B, KDM4A, VGLL4, BZW1, RAPGEF2, DHX34, ST18, ZNF646, SETD1A, SLK, ZFYVE16, EIF4A3, ATG13, DLGAP5, RNF40, KIAA0141, RB1CC1, ARHGEF11, ZEB2, ZBTB24, ZNF518A, NUAK1, RNF10, ZBTB5, RBM8A, OXSR1, TNFSF15, NR1I3, NR1D2, RBX1, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, PDCD6, BCL2L11, RANBP9, RAD50, FEM1B, ZNF263, TRAP1, AKAP9, RASA4, ATP6AP2, FARP1, ZNF256, RNF41, EIF1, OLIG2, PRG4, CTDSPL, SPRY1, DENND4A, IRX5, RAMP3 |
1511 | GO:0045892 | 0.00 | 1.52 | 55.70 | 75 | 240 | negative regulation of transcription, DNA-templated | BIRC5, ARNTL, BCL3, CAT, RUNX2, CENPF, CREB1, HIST1H2AD, NRG1, HMGA1, IFNA2, IGF1R, IRAK1, IRAK2, IRF1, PA2G4, PAX9, CHMP1A, PHF2, PIM1, PTGIS, PURA, RFX3, XCL1, SET, SFRP5, SIX3, SMARCE1, SOX9, SOX10, TRIM21, TBP, TSG101, TNFSF4, SUMO1, WNT11, XRCC5, ZNF24, ZNF91, ZNF154, ZNF224, KDM5C, HIST1H4I, FZD6, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, ZNF282, HAT1, HESX1, TAX1BP1, HIST1H3F, HIST1H2AG, TAF1B, TAF1A, UBA3, CBFA2T2, CLOCK, KDM4A, NR1I3, NR1D2, ZBTB33, HDAC6, ZNF263, ZNF256, RAMP3 |
1512 | GO:1904951 | 0.00 | 1.52 | 67.12 | 90 | 284 | positive regulation of establishment of protein localization | ABAT, ABL1, ABL2, ACTL6A, AGTR2, ALOX15B, ANG, ARF1, BAD, BLK, BMP4, BMPR1A, CASP5, CD58, CDH1, CHRM1, CRH, CSF1R, CSNK2A2, CTSK, DKC1, EDA, EPHA2, F2R, FGA, FGR, GCG, KAT2A, GLUD1, GPLD1, GPR26, FFAR1, HCLS1, NRG1, HNMT, IFNG, IGF1, IL1A, IL10, IL12B, IL13, IL18, INS, ISL1, ITGB1, KCNN4, KPNA1, IPO5, SMAD3, OAZ1, OAZ2, OXCT1, P2RX7, PAEP, PCM1, PPID, PRKCE, PRKCI, PRKCQ, RAC2, RNASE2, SLC9A1, TRIP6, TRPM2, TSG101, TNFSF4, UBE2L3, NR1H2, VIL1, YWHAZ, ZIC1, ZBTB17, FZD5, ARHGEF5, BAP1, RUVBL1, DYNLL1, TNFSF14, CDKL2, IL1RL1, ITGB1BP1, NRXN1, AKAP6, ATG13, C2CD5, FAM20B, BCL2L11, SAE1, NUTF2, RAMP3 |
1513 | GO:0006402 | 0.02 | 1.52 | 31.90 | 43 | 135 | mRNA catabolic process | ZFP36L2, DDX6, EIF4A1, EIF4E, FAU, EIF3E, CNOT2, CNOT4, PPP2R1A, PPP2R2A, UPF1, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, SUPV3L1, PRPF18, KHSRP, RPL14, RPL23, GTPBP1, DHX34, EIF4A3, SMG7, RBM8A |
1514 | GO:0043903 | 0.03 | 1.52 | 25.95 | 35 | 110 | regulation of symbiosis, encompassing mutualism through parasitism | ADAR, BAD, BST2, CD28, DDX5, EP300, ERCC3, FBLN1, NR5A2, IFI16, IFIT1, IFNA2, ISG20, ITGAV, JUN, LTF, OAS3, PPIB, PPID, REST, SLPI, SMARCA4, SP1, SP100, SRPK2, TRIM21, SSRP1, STAU1, DYNLT1, TOP2A, TSG101, TRIM25, CTDP1, VAPB, BCL2L11 |
1515 | GO:1901617 | 0.02 | 1.52 | 31.20 | 42 | 132 | organic hydroxy compound biosynthetic process | ACADM, AGTR2, ASIP, CHAT, AKR1C4, CHKB, CTNS, CYP3A4, CYP8B1, CYP11B1, DBH, DHCR7, CYB5R3, PTK2B, FDFT1, FDPS, FGF7, HMGCR, HMGCS2, HRH1, IFNG, INSIG1, LCAT, LDHC, NTSR1, PAH, PCK1, PCYT1A, PRKAA1, PTAFR, REST, SHMT1, SNAI1, SNCA, SREBF1, TRPC1, TYR, CNBP, AKR1C3, RAPGEF2, ZEB2, NR1H4 |
1516 | GO:0034249 | 0.05 | 1.51 | 20.80 | 28 | 88 | negative regulation of cellular amide metabolic process | ADAR, ANG, ATF4, CIRBP, CLU, DAPK3, EIF4E, EPRS, GAPDH, GRB7, EIF3E, CAPRIN1, SMAD1, SMAD3, CNOT2, PRKAA1, PURA, RAN, RARA, RBM4, UPF1, RPS3, SRP9, TSC1, EIF4EBP3, EIF2B3, EIF2AK3, EIF4A3 |
1517 | GO:0010638 | 0.00 | 1.51 | 52.27 | 70 | 222 | positive regulation of organelle organization | ACTL6A, ANXA1, BIRC5, ATR, ATRX, BAD, BAX, BBS4, CD28, CSNK2A2, CTSK, DCN, DKC1, DNMT1, DNMT3B, DRD3, GCG, KAT2A, GPR26, HIST1H1B, NRG1, HNMT, IGF1, IGF1R, IGF2, IL1A, INS, ISL1, JARID2, KDR, CNOT2, OPA1, PIP4K2A, PRKD1, PTEN, RAC2, RB1, RNASE2, SFPQ, FSCN1, SREBF1, SURF4, SYT1, TAL1, TSG101, UBE2L3, YWHAZ, ZBTB17, FZD5, BAP1, CUL3, OGT, RUVBL1, DYNLL1, EED, HRK, TNFSF10, RPS6KA4, CDKL2, AURKB, ATG5, ATG13, DLGAP5, RNF40, C2CD5, FAM20B, PDCD6IP, BCL2L11, SAE1, RAD50 |
1518 | GO:0016477 | 0.04 | 1.51 | 22.97 | 31 | 102 | cell migration | ABL2, ANG, RERE, TSPO, CD151, VCAN, CSPG4, CTGF, CTTN, EPHA8, EPHB3, ERG, FUT8, HEXB, IL12B, PIK3C2B, PRKCI, PSG2, RAB1A, SCNN1B, SIX3, SLC9A1, FSCN1, USP9Y, CUL3, SORBS2, CDC42BPB, SDC3, GAB2, ARPC5, ABI2 |
1519 | GO:0051235 | 0.05 | 1.51 | 20.82 | 28 | 89 | maintenance of location | ABCA1, ACACB, ALB, ARL2, ATP2A1, BBS4, BCL3, TSPO, C3, CD4, CD36, CRP, FBN1, GAA, GM2A, HEXB, IL10, ITGAV, TONSL, SPAG4, STAT5B, TRIP6, NR1H2, UVRAG, NRIP1, DGAT1, TNFSF14, LATS1 |
1520 | GO:0034655 | 0.01 | 1.51 | 38.05 | 51 | 162 | nucleobase-containing compound catabolic process | AHCY, ZFP36L2, CDA, DDX6, TYMP, EIF4A1, EIF4E, FAU, FEN1, EIF3E, CNOT2, CNOT4, PPP1R8, PPP2R1A, PPP2R2A, UPF1, RNASE2, RNASE6, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, SUPV3L1, PRPF18, KHSRP, RNASET2, RPL14, RPL23, GTPBP1, DHX34, EIF4A3, SMG7, RBM8A |
1521 | GO:0034654 | 0.00 | 1.51 | 512.36 | 640 | 2180 | nucleobase-containing compound biosynthetic process | ABCA1, ABCA2, ABL1, ACACB, ACTL6A, ACTN1, ACVR2B, ADSS, AEBP1, AGTR2, NR0B1, AK1, AK2, ALK, ALX3, AMPD1, AMPD2, ANG, ANXA3, XIAP, BIRC5, APP, APRT, PHOX2A, ARNT, ARNTL, ASCL1, ASCL2, ATF4, RERE, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, ATRX, AVPR2, BACH1, BCL3, PRDM1, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTK, CALM3, CAMK2A, CAT, RUNX2, CBL, CCNC, CCNE1, CCNT2, CD3D, CD28, CD86, TNFSF8, CD36, CDA, CDK11B, CDH1, CDK2, CDK8, CDX2, CEBPE, CENPB, CHD2, CHD4, CHEK1, CHUK, CLU, COL1A1, COX6A1, COX6B1, COX7C, COX8A, CREB1, CRH, CRX, CRY2, CSNK2A1, CSNK2A2, CSTF3, CTH, CTNND2, DAPK3, DCN, DDX1, DDX5, DHFR, DLX5, DNM2, DNMT1, DNMT3B, DRD3, DRD5, ARID3A, RCAN1, TSC22D3, E2F6, E4F1, EBF1, TYMP, ECM1, EDA, S1PR1, LPAR1, EDNRA, EFNA1, EGR2, EGR3, EGR4, ELAVL2, ELK1, EMX1, EMX2, EN1, EP300, EPHA5, EYA4, ERCC3, ERCC6, ERF, ERG, ESRRG, ETS1, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA2, EZH1, F2R, FAU, FBN1, EFEMP1, FGF4, FGF7, FGFR3, FSHB, FSHR, NR5A2, FZD2, GALR1, GATA4, GATA6, GCG, KAT2A, GDF9, GHRHR, GPC3, GMDS, GNAS, GPX2, GSC2, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GUCY2D, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, HBE1, HCLS1, HDGF, HEXB, NRG1, HHEX, HIC1, HIP1, HIVEP2, HLF, HMGN1, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD8, HOXD9, HOXD10, HOXD12, HPRT1, HSF4, HTR2C, ICAM1, IFI16, SP110, IFNA2, IFNG, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL10, ILK, IMPDH1, IMPDH2, ING2, INS, INSIG1, IRAK1, IRAK2, IRF1, IRF5, ISL1, JARID2, JUN, JUND, KIT, LDHC, LMO1, LTF, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MEOX2, CIITA, ATXN3, AFF1, FOXO4, PPP1R12A, DRG1, TONSL, CNOT2, YBX1, NTRK2, NTRK3, NUP98, ORC1, ORC2, OTX1, OTX2, OVOL1, P2RY11, PA2G4, PRDX1, SERPINE1, PALM, PAM, PAX3, PAX9, PCK1, CHMP1A, PDE8A, PFAS, PGR, PHF2, PIM1, PPID, PPP1R8, PPP2R1A, PPP5C, PRIM2, PRKAA1, PRKAG1, PRKAR1A, PRKCI, PRKD1, PRPSAP1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PTAFR, PTEN, PTGIS, PTMA, PURA, RAD21, RAF1, RAN, RANBP2, RARA, RARB, RB1, RBL2, RCVRN, DPF2, REST, RFX1, RFX3, RFXAP, RGS12, RHEB, RLF, RNF6, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS6KA1, RPS11, RPS19, RPS20, RPS27, RRM1, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A12, SALL1, SATB1, XCL1, TRAPPC2, SET, SFPQ, SFRP5, SRSF1, SRSF5, SRSF7, SFSWAP, SGK1, SHMT1, SIM2, SIX3, SLC9A1, SMARCA1, SMARCA2, SMARCA4, SMARCD3, SMARCE1, SNAI1, SNAPC3, SNCA, SNRPE, SNRPF, SOD2, SOX3, SOX9, SOX10, SOX11, SP1, SP100, UAP1, SPIB, SREBF1, SRF, SRY, TRIM21, SSRP1, STAT2, STAT3, STAT4, STAT5B, STAT6, TAF4B, TAF7, TAF10, TAL1, TBL1X, TBP, HNF1A, ZNF354A, NR2F1, NR2F2, KLF10, TMPO, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TSC1, TSG101, TTF1, TULP3, TNFSF4, UBE2D2, UBE2L3, UBE3A, SUMO1, UCP1, SCGB1A1, NR1H2, UPP1, USF1, VAV1, VIP, VIPR2, WFS1, WNT1, WNT11, XRCC5, YY1, YWHAZ, ZFP37, ZFPL1, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF91, ZNF99, ZNF124, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZXDA, PRDM2, FZD5, ARHGEF5, NUP214, FOSL1, FGF23, AAAS, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, USP9Y, HIST1H4I, PICALM, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, CUL3, CUL2, KLF11, SMARCA5, OGT, IKBKG, IKBKAP, HAT1, GAS7, PIR, BLZF1, KHSRP, STK16, RGS20, RUVBL1, KLF7, TP63, CHRD, DYNLL1, SRSF9, TRADD, EED, RIPK1, RIPK2, SUCLG1, SAP30, HESX1, PER3, TAX1BP1, BUD31, PHOX2B, KYNU, HIST1H3F, HIST1H2AG, RPS6KA4, TNFSF18, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, RPL14, PAPSS1, USP2, PDLIM1, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, DDX21, CCPG1, ITGB1BP1, ZNF235, COPS2, TRIP11, HMGN3, GTF3C5, GTF3C4, GTF3C3, RPL23, RECQL5, ZRANB2, HAND1, ZNF264, EIF2AK3, FHL5, AKAP6, ATG5, ONECUT2, LITAF, TBPL1, ZNF254, GABBR2, CLOCK, SOX13, RBM39, AKAP12, RNF14, GUCA1C, NUP155, ZNF516, KDM4A, VGLL4, NUP93, BZW1, ST18, ZNF646, SETD1A, ZFYVE16, RB1CC1, ARHGEF11, ZEB2, ZBTB24, ZNF518A, RNF10, ZBTB5, RBM8A, NR1I3, NR1H4, NR1D2, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, ZNF263, SLC25A13, ZNF256, RNF41, OLIG2, DENND4A, IRX5, RAMP3 |
1522 | GO:0010564 | 0.01 | 1.51 | 37.34 | 50 | 160 | regulation of cell cycle process | BBS4, BMP4, BRCA2, BUB1B, CALM3, CCNF, CDC20, CDC25C, CDC27, CENPE, CENPF, CHEK1, CSNK2A1, CSNK2A2, DAPK3, DUSP1, E4F1, ERCC3, FGFR3, GPR3, NUBP1, OVOL1, CHMP1A, PIM1, PPP2R1A, PRKAR1A, PRKCQ, PTPN6, RPA2, SIX3, SKP1, SMARCA4, SOX9, SOX11, ADAM17, TTK, UVRAG, ZNF207, SMC1A, CUL1, CDC23, CDC16, SMC3, ZW10, MAD2L1BP, CUL7, KLHL21, PDCD6IP, FEM1B, CTDSPL |
1523 | GO:0048522 | 0.01 | 1.50 | 41.48 | 56 | 204 | positive regulation of cellular process | ACTL6A, ADAR, ADGRB2, BBS4, BCR, BICD1, CSNK2A2, CTSK, DPP6, EPHA2, CTTN, EPHB1, EPHB2, EPHB3, GPM6A, GPR26, FFAR3, HNMT, IFIT1, KCNC2, KCNH2, KCNJ2, KCNJ11, KCNQ1, ATXN3, CNOT2, PFDN2, PPIB, RALA, RNASE2, CLIP1, S100A1, SFTPD, SLC34A1, FSCN1, STC1, SURF4, TPBG, TULP1, CLRN1, SLC30A2, BAP1, PIK3R3, RUVBL1, CDKL2, NRXN3, AKAP7, FRMPD4, C2CD5, FAM20B, SAE1, ARPC5, ARPC1B, ACTR2, ABI2, WASF2 |
1524 | GO:0050688 | 0.05 | 1.50 | 22.41 | 30 | 95 | regulation of defense response to virus | ANXA5, BIRC3, CD37, COX8A, FGF7, GABRA5, IFIT1, IL2RA, IL12B, KCNQ1, NTHL1, PCBP2, PDK4, PEX13, PPM1B, SCN1A, SEC14L1, SNRPD1, STAT2, ZNF189, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H3F, CHST3, NUP93, PHYHIP, FGFBP1 |
1525 | GO:0009887 | 0.02 | 1.50 | 32.15 | 43 | 140 | organ morphogenesis | CDX2, CRKL, CRX, CTSH, DCN, S1PR1, EFNA1, ELN, EMX1, EP300, ERG, FGD1, NR5A2, GAA, GATA4, GPC3, HCCS, NRG1, FOXA2, IGF2, ILK, JUN, SMAD7, PRKX, PSPN, PTEN, PTK2, RFNG, RYR1, RYR2, SFTPB, STIL, SNAI1, SOX3, SRF, TNNC1, TNNI3, KDM6A, CUL1, ADAM15, BAZ1B, ONECUT2, COL4A3BP |
1526 | GO:0006796 | 0.00 | 1.50 | 108.82 | 144 | 497 | phosphate-containing compound metabolic process | ACP1, ADAM10, ALPI, ALPPL2, BIRC5, ATP1A1, ATR, AXL, BCR, BLK, BTK, BUB1B, CDK11B, CDK2, CDK3, CDK6, CDK8, CHAT, CHEK1, CHKB, CHUK, CKM, CLK1, CLK3, CPS1, CREB1, CSNK1G3, CSNK2A1, CSNK2A2, CTSH, DGKB, DAPK3, DBI, ELK1, EPHA5, EPHB2, EPHB3, EYA4, ERCC3, ERG, EYA2, EFEMP1, FDFT1, FDPS, FYB, G6PC, GALK2, GATA6, GK2, GPD2, HEXB, IL12RB2, INPP1, INPPL1, INSRR, ITGAV, KCNH2, LCAT, LIMK1, LIPC, LIPE, SMAD1, SMAD9, CIITA, OXTR, PCYT1A, PDK4, PHKA2, PHKB, PHKG1, PIK3C2B, PI4KA, PIP4K2A, PPM1B, PPP2CB, PPP4C, PPP6C, PRKCI, PRKCQ, PRKX, PSKH1, PSPH, PTPN4, PTPN7, PTPRE, PTPRH, PTPRN, PTPRN2, PTPRS, RARA, RBM4, RPS6KA1, RPS6KB1, RPS6KB2, SBF1, SGK1, SKP1, SLC20A1, SORD, SRPK2, STAT4, TOP1, NR2C2, TYRO3, VRK1, SCG2, DYRK2, CUL1, PPM1D, CDC14B, STK16, DGAT1, RIOK3, DYRK4, CDKL1, DPM2, INPP4B, SYNJ1, CDKL2, BAZ1B, DYRK1B, CTDP1, DGKI, AURKB, STK17B, STK17A, LIPG, PICK1, PIGL, MINPP1, CDC42BPB, AATK, DLGAP5, PTDSS1, DNAJC6, FAM20B, XYLB, GNE, PIGK, SH2D3C, SH2D3A, COL4A3BP, SGK2, ABI2 |
1527 | GO:0032102 | 0.05 | 1.49 | 23.27 | 31 | 99 | negative regulation of response to external stimulus | ABAT, ANGPT2, ANXA5, APOH, BBS4, PRDM1, TSPO, F2, FAP, FGA, GCG, GP1BA, HMGCR, HRG, IFIT1, KLKB1, KNG1, LTF, SERPINE1, PCBP2, PPM1B, SEC14L1, SEMA3F, TNR, TSC1, USF1, VTN, SEMA3B, NRP1, FEZ2, SEMA3E |
1528 | GO:0071310 | 0.04 | 1.49 | 23.06 | 31 | 111 | cellular response to organic substance | ADD1, ATF4, BAX, CD9, TPP1, CTH, EFNA5, EGR2, EPHA5, EXTL3, HDGF, HMGCR, FOXA2, ATXN3, OXCT1, PSAP, PTPRN2, SLC2A5, SRF, SULT1A3, SYP, WFS1, ZNF16, ZBTB17, VAPB, HMGN3, NRXN1, EIF2AK3, GOSR2, TATDN2, CUL7 |
1529 | GO:0051052 | 0.02 | 1.49 | 33.92 | 45 | 144 | regulation of DNA metabolic process | ANXA3, ATR, ATRX, BMP4, BRCA2, CD28, CDK2, CHEK1, DNMT1, ERCC4, HNRNPC, IFNG, IGF1, IGF1R, IL10, INS, JUN, KPNA1, KPNA2, KITLG, MGMT, PCNA, PPP2R1A, PPP4C, RAC1, RAD51, RBBP6, RPA2, RPS3, S100A11, SETMAR, SHC1, STAT6, TOP2A, TTF1, TNFSF4, UNG, XRCC5, ZNF91, SMC1A, CUL4A, RNF8, SMC3, IL27RA, RAD50 |
1530 | GO:0090316 | 0.02 | 1.48 | 31.67 | 42 | 134 | positive regulation of intracellular protein transport | ACTL6A, BMP4, BMPR1A, CDH1, CHRM1, CSNK2A2, CTSK, EDA, KAT2A, GPR26, HCLS1, NRG1, HNMT, IGF1, IL12B, IL18, KPNA1, IPO5, SMAD3, OAZ1, OAZ2, PCM1, PRKCQ, RAC2, RNASE2, SLC9A1, TRIP6, UBE2L3, ZIC1, ZBTB17, FZD5, BAP1, RUVBL1, TNFSF14, CDKL2, ITGB1BP1, AKAP6, ATG13, C2CD5, FAM20B, SAE1, NUTF2 |
1531 | GO:0000819 | 0.05 | 1.48 | 23.40 | 31 | 99 | sister chromatid segregation | ATRX, BUB1B, CCNB1, CDC20, CDC27, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, KIF25, CHMP1A, PPP2R1A, PTEN, RAD51C, RB1, SFPQ, TOP2A, TOP2B, TTK, ZNF207, SMC1A, CUL3, CDC23, CDC16, LATS1, SMC3, ZW10, DLGAP5, REC8, SMC4 |
1532 | GO:0032990 | 0.00 | 1.48 | 155.27 | 202 | 657 | cell part morphogenesis | ABL1, ABL2, ACTB, ADAM10, ANGPT1, APP, ARAF, ARHGAP4, RERE, BAX, BBS4, BCL2L1, BMPR2, CACNA1A, CACNB4, CALM3, CAMK2A, CD72, CHN1, CHRNB2, AP2S1, CLU, CNP, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2RB, CSNK1D, CSNK2A1, CSNK2A2, CTNND2, DCC, DLG3, DLX5, DNM1, DNM2, DPYSL3, EPYC, DUSP5, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EPHA2, EMX1, CTTN, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, ETV4, FGF3, FGF4, FGF7, FGFR3, FYN, GDI1, GFRA1, GOLGA4, GPM6A, GRB2, GRIN2A, NRG1, ONECUT1, HPRT1, IL2RA, ILK, ISL1, ITGA1, ITGA5, ITGA9, ITGAV, ITGB1, KIF5A, KIT, LIMK1, CAPRIN1, MARK3, KITLG, NRCAM, NTF4, NTRK2, NTRK3, NTN3, OTX2, PCM1, PPP5C, PRKCQ, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, PTPRA, RAC1, RAC2, RAF1, RAP2A, RASA2, RFX3, RNF6, RPGR, RPL24, RPS6KA1, RYK, SCN5A, SEMA3F, SGK1, SHC1, STIL, SOS2, SRF, SUPV3L1, SYT1, SYT4, CNTN2, TBCE, DYNLT1, TNR, TOP2B, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, VIL1, SEMA3B, FGF23, RND2, USP9X, PICALM, CUL3, CNTNAP1, GAS7, KLF7, UNC5C, NUMB, DYNLL1, PEA15, NRP2, NRP1, ARHGEF7, PHOX2B, RPS6KA4, ATP6V0D1, ARHGEF1, SNAP29, SLIT2, NRXN3, NRXN1, ATG5, ONECUT2, PSMF1, NRG2, AATK, FEZ2, RAPGEF2, RIMS2, SEMA3E, IFT140, CUL7, ARHGEF11, RBX1, RANBP9, COL4A3BP, ARPC5, ARPC1B, ACTR2, ARPC2, AKAP9, RASA4, FARP1, WASF2, PSME3, PSMD14, ABCC4 |
1533 | GO:0070887 | 0.04 | 1.48 | 24.64 | 33 | 121 | cellular response to chemical stimulus | ACY1, ADH5, AHCY, COMT, CYP2A6, CYP2A13, CYP2F1, CYP3A4, CYP8B1, ESD, ETV5, GPX1, GSTZ1, HP, KCNH2, PCP4, PTGS1, QDPR, RAP2A, RYK, SFPQ, STAU1, SULT1E1, SULT1C2, SULT2B1, TPMT, TRPM2, CES2, PAPSS1, EFTUD2, GSTO1, BAG5, DHRS2 |
1534 | GO:0051171 | 0.00 | 1.47 | 546.16 | 672 | 2311 | regulation of nitrogen compound metabolic process | ABAT, ABCA1, ABCA2, ABL1, ACTL6A, ACTN1, ACVR2B, ACVRL1, ADAR, AEBP1, AGTR2, NR0B1, ALK, ALX3, ANG, ANXA3, APAF1, XIAP, BIRC5, APP, PHOX2A, ARNT, ARNTL, ASCL1, ASCL2, ASS1, ATF4, RERE, ATR, ATRX, AVPR2, BACH1, BARD1, BAX, BCL3, BHMT, PRDM1, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTK, TSPO, CALM3, CAMK2A, CAT, RUNX2, CBL, CCNB1, CCNC, CCNE1, CCNT2, CD3D, CD28, CD86, TNFSF8, CD36, CDA, CDK11B, CDH1, CDK2, CDK4, CDK8, CDKN1A, CDX2, CEBPE, CENPB, CENPF, CHD2, CHD4, CHEK1, CHRNB2, CHUK, CIRBP, CLU, CLK1, CLK3, COL1A1, COMT, CREB1, CRH, CRX, CRY2, CSNK2A1, CSNK2A2, CTH, CTNND2, DAPK3, DAZ1, DCN, DDX1, DDX5, DDX6, DFFA, DHFR, DKC1, DLX5, DNM2, DNMT1, DNMT3B, DRD3, DRD5, ARID3A, RCAN1, TSC22D3, DUSP1, E2F6, E4F1, EBF1, ECM1, EDA, S1PR1, LPAR1, EDNRA, EFNA1, EGR2, EGR3, EGR4, EIF2B1, EIF4A1, EIF4E, EIF4G2, EIF5, EIF5A, ELAVL2, ELAVL1, ELK1, EMX1, EMX2, EN1, EP300, EPHA5, EPRS, EYA4, ERCC3, ERCC4, ERCC6, ERF, ERG, ESRRG, ETS1, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA2, EZH1, F2R, PTK2B, FBN1, EFEMP1, FGF4, FGF7, FGFR3, AFF2, FSHB, FSHR, NR5A2, FZD2, GALR1, GAPDH, GATA4, GATA6, GCG, KAT2A, GDF9, GHRHR, GPC3, GNAS, GRB7, GSC2, GTF2I, GTF3A, BRF1, GUCA1A, GUCA2A, GUCA2B, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, HBE1, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIP1, HIVEP2, HLF, HMGN1, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HNRNPC, HOXC10, HOXC11, HOXD8, HOXD9, HOXD10, HOXD12, HPRT1, HSF4, HSPB1, ICAM1, IFI16, SP110, IFNA2, IFNG, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL10, ILK, ING2, INS, INSIG1, EIF3E, IRAK1, IRAK2, IRF1, IRF5, ISL1, JARID2, JUN, JUND, KCNK2, KIT, KPNA1, KPNA2, LMO1, LTF, CAPRIN1, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MEOX2, KITLG, MGMT, CIITA, ATXN3, AFF1, FOXO4, PPP1R12A, TONSL, CNOT2, YBX1, NTRK2, NTRK3, NVL, OAS3, OAZ1, OAZ2, ORC1, ORC2, OTX1, OTX2, OVOL1, P2RX4, P2RX7, P2RY11, PA2G4, SERPINE1, PALM, PAM, PAX3, PAX9, PCK1, PCNA, CHMP1A, PDE8A, PGAM1, PGR, PHF2, PIM1, PPID, PPP1R8, PPP2R1A, PPP4C, PRKAA1, PRKAG1, PRKAR1A, PRKCI, PRKD1, PRKCQ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTAFR, PTEN, PTGIS, PURA, RAC1, RAD21, RAD51, RAF1, RAN, RARA, RARB, RB1, RBBP6, RBL2, RBM4, RCVRN, UPF1, DPF2, REST, RFX1, RFX3, RFXAP, RLF, RNF6, RPA2, RPL38, RPS3, RPS6KA1, RPS6KB1, RPS6KB2, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A11, S100A12, SALL1, SATB1, XCL1, TRAPPC2, SET, SETMAR, SFPQ, SFRP5, SRSF7, SFSWAP, SGK1, SHC1, SIM2, SIX3, SLC9A1, SMARCA1, SMARCA2, SMARCA4, SMARCD3, SMARCE1, SNAI1, SNAPC3, SNCA, SNRNP70, SOD2, SOX3, SOX9, SOX10, SOX11, SP1, SP100, SPIB, SREBF1, SRF, SRP9, SRPK2, SRY, TRIM21, SSRP1, STAT2, STAT3, STAT4, STAT5B, STAT6, SUPV3L1, TACR3, TAF4B, TAF7, TAF10, TAL1, TBL1X, TBP, HNF1A, ZNF354A, NR2F1, NR2F2, KLF10, TMPO, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TSC1, TSG101, TTF1, TULP3, TNFSF4, TYMS, UBB, UBE2D2, UBE2L3, UBE3A, SUMO1, UCP1, SCGB1A1, UNG, NR1H2, USF1, VAV1, VIP, VIPR2, TRPV1, EIF4H, WFS1, WNT1, WNT11, XRCC5, YY1, ZFP37, ZFPL1, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF91, ZNF99, ZNF124, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZXDA, PRDM2, FZD5, ARHGEF5, FOSL1, FGF23, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, SMC1A, USP9Y, HIST1H4I, PICALM, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NSMAF, CUL4A, CUL3, CUL2, KLF11, SMARCA5, OGT, IKBKG, IKBKAP, HAT1, GAS7, PIR, BLZF1, KHSRP, STK16, RGS20, RUVBL1, KLF7, TP63, EIF4EBP3, CHRD, PDE5A, DYNLL1, EIF3G, EIF4G3, SRSF9, TRADD, EED, RIPK1, RIPK2, SAP30, HESX1, PER3, TAX1BP1, EIF2B3, EIF2B2, BUD31, PHOX2B, HIST1H3F, HIST1H2AG, RPS6KA4, TNFSF18, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, USP2, RGN, PDLIM1, SMC3, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, AURKB, VAPB, CCPG1, ITGB1BP1, ZNF235, KLF4, COPS2, TRIP11, HMGN3, RECQL5, ZRANB2, HAND1, ZNF264, EIF2AK3, FHL5, IL27RA, AKAP6, ONECUT2, PSMF1, LITAF, TBPL1, ZNF254, GTPBP1, GABBR2, CLOCK, SOX13, RBM39, AKAP12, RNF14, GUCA1C, ZNF516, EIF5B, KDM4A, VGLL4, BZW1, DHX34, ST18, ZNF646, SETD1A, ZFYVE16, EIF4A3, RNF40, RB1CC1, ARHGEF11, ZEB2, ZBTB24, ZNF518A, RNF10, ZBTB5, RBM8A, NR1I3, NR1H4, NR1D2, RBX1, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, RAD50, ZNF263, TRAP1, ZNF256, RNF41, PSME3, EIF1, PSMD14, OLIG2, DENND4A, IRX5, RAMP3 |
1535 | GO:0048518 | 0.00 | 1.47 | 53.45 | 71 | 270 | positive regulation of biological process | ACTG2, AMPH, TRIM23, ARHGDIB, ARL1, RCBTB2, CLPS, DHFR, EIF2B1, GCGR, GDI1, GDI2, GM2A, GNA15, GNAQ, GNAT1, HSPB2, LLGL2, PPP1R12B, OSBP, SERPINB9, RAB4A, RABIF, RANBP1, RANGAP1, RGS10, RGS12, RGS13, RPGR, SBF1, SFTPB, SIPA1, TBCD, KDM6A, VIM, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, RGS20, S1PR4, EIF2B3, EIF2B2, HERC2, HIST1H3F, TAF1B, TAF1A, RABEP1, ARHGEF1, DDX21, TRIP10, GTF3C4, ARHGAP29, SEC22B, RIN1, RALGPS1, ARHGAP32, ACAP1, SGSM2, ARHGAP25, UBA2, FARP1, DENND4A |
1536 | GO:0061136 | 0.03 | 1.47 | 28.83 | 38 | 122 | regulation of proteasomal protein catabolic process | ARAF, BUB1B, CCNB1, CDC20, CDC27, CENPF, CLU, CSNK1D, CSNK2A1, CSNK2A2, DUSP1, GPX1, UBE2K, DNAJB2, SMAD7, PSMC1, PSMC2, PSMC3, PSMC4, PTEN, RAD23B, RB1, TTK, UBB, SUMO1, ZNF207, CUL3, CDC23, CDC16, USP14, ZW10, PSMF1, BAG5, RNF14, DLGAP5, RNF40, PSME3, PSMD14 |
1537 | GO:0071822 | 0.01 | 1.47 | 53.16 | 70 | 234 | protein complex subunit organization | ABL2, ACTN1, BRDT, COL11A1, CTGF, DAPK3, DYNC1H1, S1PR1, LPAR1, EIF5A, EML1, EMP2, FAU, GHSR, INPPL1, KRT9, LIMK1, MYO1B, P4HA1, PCM1, PRKCI, PRKCQ, RAC2, RAN, UPF1, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3A, RPS4Y1, RPS6, RPS11, RPS20, RPS27, SDC4, STIL, SMARCA4, SMARCD3, SMARCE1, HSP90B1, TTK, CLRN1, VIM, WNT11, SMC1A, SORBS2, RNF8, RPL14, SMC3, ARHGEF2, RPL23, ADAMTS3, ADAMTS2, BCAR1, SLK, CKAP5, DNAJC6, SMC4, WASF2 |
1538 | GO:0046394 | 0.01 | 1.47 | 41.83 | 55 | 177 | carboxylic acid biosynthetic process | ABAT, ACACB, ACADM, AHCY, ALDH1A3, ALOX15B, ANXA1, ASL, ASS1, BHMT, CBR1, CDO1, AKR1C4, CPS1, VCAN, CSPG4, CTH, CYP8B1, DCN, DHFR, GAD1, GATM, GGT7, GLUD1, GOT2, GPT, HPGD, IDO1, INSIG1, LDHC, LIPC, LTA4H, OAT, PAH, PDK4, PRKAA1, PRKAG1, PSPH, PTGIS, PTGS1, ABCD3, PYCR1, RBP1, ACSM3, SHMT1, SHMT2, NR1H2, UROS, AKR1C3, ALDH4A1, KYNU, RGN, GSTO1, NR1H4, DHRS9 |
1539 | GO:0006915 | 0.01 | 1.46 | 44.05 | 58 | 200 | apoptotic process | ACTN1, ADD1, ALK, ALOX15B, ALX3, BMP1, BMP3, BMP8B, BUB1B, CASP5, TNFSF8, CDK11B, CDH1, CSE1L, CSNK2A2, DNASE1, DNASE1L3, EIF5A, ETS1, FLT3, GAS1, GAS2, GDF9, GZMH, IAPP, IFNA2, INHA, IRF1, KPNA1, PAEP, PAX3, PRKCE, PRKD1, PTPN6, PTPRH, RAD21, SATB1, SFRP5, SHB, STK10, VIM, FZD5, AIMP2, DPF1, OGT, IKBKG, TNFSF9, RABEP1, BCL7C, BCL7B, LITAF, GDF15, BCAR1, TRAF4, SLK, OXSR1, PDCD6IP, SGK2 |
1540 | GO:0048666 | 0.01 | 1.46 | 47.24 | 62 | 207 | neuron development | ALK, ARF1, BBS4, PRDM1, BMP4, TSPO, CDC20, CDH1, CLU, CNR1, CTF1, CTNNA1, DHFR, LPAR1, EMX1, EN1, PTK2B, EFEMP1, FZD2, GABRA5, GFAP, GNAT1, GNAT2, GNGT1, GPM6A, RAPGEF1, GRID2, HGF, IHH, JUN, NTF4, P2RY2, PALM, PCP4, SERPINF1, PRKCI, PRKD1, PTN, RPGR, RXRA, SDC4, SNAP25, SOX3, SPOCK1, STRN, SYT1, SYT4, DYNLT1, TP73, TULP1, VIM, WNT1, GAS7, CBFA2T2, KLF4, CHST3, SLC4A7, BAG5, RIMS2, IFT140, KIAA0319, NR2E3 |
1541 | GO:1901575 | 0.00 | 1.46 | 222.25 | 284 | 946 | organic substance catabolic process | ADH5, ADRA1B, ALDOC, APAF1, APOH, ARAF, ARNT, ARNTL, STS, BAD, BARD1, BAX, BHMT, BLVRA, BNIP3L, ZFP36L2, BUB1B, DAGLA, CALM3, CAPN1, CAT, CAV3, CBL, CBLB, CCNB1, CCNF, ENTPD2, CD44, CDA, CDC20, CDC27, CDK2, CENPF, CLU, TPP1, CLN5, CLPS, CNP, COMT, CPS1, CSNK1D, CSNK2A1, CSNK2A2, VCAN, CSPG4, CTSE, CTSH, CTSK, CYP2A6, CYP3A4, DBH, DCN, ACE, DDX6, DFFA, DNASE1, DNASE1L1, DNASE1L2, DNASE1L3, DUSP1, TYMP, EIF4A1, EIF4E, ENO2, ESD, FABP2, FABP7, PTK2B, FAP, FAU, FEN1, GPC4, FUT6, FUT8, FYN, G6PC, GAA, GALC, GALE, GALNS, GAPDH, GK2, GPC3, GM2A, GPD2, GPLD1, GPX1, GRIN2A, HEXA, HEXB, NRG1, UBE2K, HPRT1, DNAJB2, IDH1, IDS, IFNG, IGF1, IL10, INPP1, INS, EIF3E, ISG20, KPNA1, LIPC, LTA4H, SMAD3, SMAD7, ATXN3, CNOT2, CNOT4, NTHL1, NTSR1, OAZ1, OAZ2, OMD, OVGP1, OXCT1, P2RX7, PCBP2, PDE4B, PDE8A, PGAM1, PHKA2, PHKB, PHKG1, PPP1R8, PPP2CB, PPP2R1A, PPP2R2A, PPP2R5D, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKCE, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, PYGB, PYGM, RAD23B, RB1, RBBP6, UPF1, RNASE2, RNASE6, RNF6, RPE, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, SDC4, SETMAR, SKP1, SLC9A1, SUMO3, SOX9, STAT3, SUPV3L1, TBL1X, TNFRSF1B, HSP90B1, TRAF2, TSG101, TTC3, TTK, UBB, UBA7, UBE2D2, UBE2H, UBE2L3, UBE3A, SUMO1, UNG, USP4, UPP1, UVRAG, VIP, WFS1, WNT1, TRIM25, ZNF207, RNF103, FGF23, GAN, CLPP, USP11, USP9X, USP9Y, BAP1, CUL4A, CUL3, CUL2, CUL1, OGT, COPS3, PRPF18, KHSRP, RNASET2, AKR1C3, PDE5A, CDC23, CTSF, RIPK1, SYNJ1, CDC16, HERC2, MBD4, MGAM, RNF8, RPL14, USP14, USP2, USP8, RGN, ZW10, AURKB, SOCS6, RPL23, UBE4A, LIPG, PSMF1, BAG5, SEC22B, GTPBP1, CLOCK, RNF14, RNF7, SDC3, UBE3C, DHX34, EIF4A3, SNX17, DLGAP5, TATDN2, RNF40, CUL7, SMG7, KLHL21, RBM8A, USP3, RBX1, HDAC6, PDCD6IP, RNF41, PSME3, PSMD14, ZMPSTE24 |
1542 | GO:0006281 | 0.01 | 1.46 | 51.22 | 67 | 218 | DNA repair | ACTL6A, ATRX, BACH1, BARD1, BRCA2, CDK2, CHEK1, CSNK1D, DDX1, EP300, EYA4, ERCC3, EYA2, HMGN1, KPNA2, MGMT, ATXN3, TONSL, PPP4C, PPP5C, RAD21, RAD23B, RAD51, RAD51C, RAD51B, UPF1, REV3L, RPS3, SETMAR, SFPQ, SUMO3, SSRP1, UBA7, SUMO1, UVRAG, XPA, XRCC2, XRCC5, YY1, TRIM25, CHAF1B, SMC1A, HIST1H4I, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, SMARCA5, COPS3, CDC14B, RUVBL1, ALKBH1, HERC2, BAZ1B, SMC3, COPS2, RECQL5, CHD1L, KDM4A, USP3, RBX1, REC8, RAD50, PSMD14 |
1543 | GO:0051650 | 0.03 | 1.46 | 32.85 | 43 | 139 | establishment of vesicle localization | AMPH, ARCN1, ARF1, BBS4, CACNA1A, CANX, CD59, COPA, CSNK1D, DNM1, DNM2, GOLGA2, GRIA1, ITGA4, P2RX7, PFN2, SEPT5, PPP6C, RAB1A, RAB5A, RAB27A, TRAPPC2, SNAP25, SNCA, SYN1, SYT1, SYT5, CUL3, IKBKG, AP3B1, USO1, STX11, LIN7A, SYNJ1, AP3D1, COPB2, SNAP29, KIF3B, GOSR1, SEC22B, GOSR2, RIMS2, AP1M2 |
1544 | GO:0016482 | 0.00 | 1.45 | 106.58 | 138 | 460 | cytoplasmic transport | ADAR, ARCN1, ARL1, ARNTL, RERE, BGLAP, TSPO, VPS51, CBLB, SCARB2, CD59, CD63, CDX2, AP1S1, COPA, CSE1L, CSNK1D, DYNC1H1, DNM2, EGR2, EIF4E, EIF5A, EMP2, EPS15, F7, F10, FAU, FYB, GFER, GLE1, GOLGA2, GOLGA4, GOLGB1, GRIA1, HHEX, HSPA4, HSPA9, IFNG, INS, JUN, KPNA2, KPNA3, KPNA4, NUP98, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PPP6C, PROC, PEX19, PEX5, RAB1A, RAB5A, RAB5B, RAB6A, RAN, RANBP2, UPF1, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, SORT1, TRAPPC2, SET, SRSF1, SRSF5, SRSF7, SIX3, SRP9, SRP14, STAT3, STYX, HSP90B1, TSC1, TSG101, NUP214, ANP32A, CLTCL1, EEA1, CUL3, AP3B1, BLZF1, USO1, AKR1C3, DYNLL1, SRSF9, PROZ, AP1M1, AP3D1, RPL14, SEC22C, ZW10, VAPB, COPB2, TRIP11, RPL23, RAB9A, ZFYVE9, COG1, PEX16, GOSR1, SEC22B, VPS26A, GOSR2, NUP155, IPO13, NUP93, ZFYVE16, SNX17, TOMM20, ZC3H11A, SMG7, SGSM2, RBM8A, ACTR2, ARFRP1 |
1545 | GO:0008104 | 0.01 | 1.45 | 44.44 | 58 | 194 | protein localization | NR0B1, BIRC5, ARL1, ATR, ATRX, BICD1, BUB1B, CD4, CENPA, CSNK1D, CTNNA1, DDX1, DIAPH1, DLG2, DLG3, DNMT3B, DPP6, EMP2, ERCC3, ETV5, FBN1, FGF7, GNGT1, GRID2, GRIN2A, HHEX, ITGA4, KCNA1, KIF5A, SMAD7, MAL, ATXN3, NUBP1, NRCAM, YBX1, RAC1, RAD21, STIL, SLC9A2, SUMO3, SOX9, SPAG4, TULP1, TULP2, TULP3, USP4, WNT11, MADCAM1, CNTNAP1, NRP1, LATS1, AURKB, NRXN2, AKAP7, RAPGEF2, CROCC, KLHL21, PIGK |
1546 | GO:0043269 | 0.03 | 1.45 | 35.26 | 46 | 152 | regulation of ion transport | ABAT, AGTR2, ARG1, ATP4A, CACNA1A, CHRM1, CHRNB2, CLCN3, CLCN6, CLCN7, CLCNKA, CLCNKB, CNR1, CRHBP, CRY2, KCNA1, KCNA3, KCNA4, KCND2, KCND3, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ14, KCNJ16, KCNS3, P2RY2, PCP4, PTAFR, RAB3B, SCN1A, SCN2A, SCN7A, SCN8A, SLC34A1, VDAC2, FGF23, VAMP8, RIPK1, KCNAB3, NRXN1, KCNK6, HCN4 |
1547 | GO:0010628 | 0.03 | 1.44 | 34.50 | 45 | 153 | positive regulation of gene expression | ACTG2, ADAR, AVPR2, PRDM1, C3, CCNB1, CD3E, CD44, CDK4, CDK6, CIRBP, CRH, CRP, CTGF, CTSH, DAZ1, DNMT1, DNMT3B, EIF5A, ELAVL1, PTK2B, FBLN1, HMX2, IL18, KLKB1, NTRK2, NTRK3, P2RX7, SERPINB9, PRKAA1, PRKAG1, PTAFR, RAB27A, RPS6KB1, RPS6KB2, SNRNP70, SRPK2, SSRP1, CNTN2, CLEC3B, KDM6A, VIM, CTDP1, RIMS2, EIF4A3 |
1548 | GO:0035556 | 0.00 | 1.44 | 71.69 | 93 | 326 | intracellular signal transduction | AGTR2, APAF1, XIAP, ARNTL, ATF4, ATP2A1, AVPR2, BCL2A1, BLK, BTK, CASQ2, CBLB, CD86, DGKB, DAPK3, DRD3, RCAN1, FYB, GNAI1, GRINA, GUCY2C, GUCY2F, GUCY2D, UBE2K, NR4A1, HRC, HSPB1, ITPR1, KCNH2, SMAD3, SMAD6, SMAD7, SMAD9, FOXO4, OPA1, PIK3C2B, PI4KA, PLN, PPM1B, PRKACB, PRKACG, PRKAR1A, PRKAR2A, PRKAR2B, PRKCI, PRKCSH, PTAFR, RGS12, RPS6, RPS6KB1, RPS6KB2, RYR1, S100A1, SCN2A, SEC14L1, SFRP5, SGK1, SOD2, SPINK1, SRPK2, TPT1, TSC1, TUFT1, TYRO3, TYROBP, VDAC2, LAT2, WFS1, XPA, ANP32A, NSMAF, CUL4A, CUL2, DYNLL1, ADAM15, INPP4B, RPS6KA4, RGN, LATS1, IL1RL1, STK17B, STK17A, AKAP7, BAG5, CDC42BPB, GAB2, NUAK1, NR1H4, ZBTB33, PDCD6, SGK2, TRAP1, RCAN2 |
1549 | GO:0010876 | 0.02 | 1.44 | 43.96 | 57 | 186 | lipid localization | ABCA1, ABCA2, ABCA3, ABCA4, ACACB, AGTR1, AGTR2, ALB, ABCD1, ANXA1, APOH, TSPO, C3, VPS51, CD36, AKR1C4, CLU, CPT1B, CPT2, CRH, CRP, ACE, DRD3, GALR1, GDF9, GM2A, GOT2, HEXB, ITGAV, KCNN4, LCAT, LIPC, NTSR1, OSBP, P2RX4, P2RX7, P2RY2, SERPINA5, PSAP, ABCD3, RXRA, SLC10A1, SLCO2A1, SLCO1A2, STAT5B, NR1H2, NRIP1, SLC10A3, FZD4, DGAT1, SLC9A3R1, LIPG, OSBPL2, NR1H4, ATP9A, COL4A3BP, ABCC4 |
1550 | GO:0051495 | 0.05 | 1.44 | 26.94 | 35 | 114 | positive regulation of cytoskeleton organization | ARF1, ARL2, CAV3, CCNB1, CTGF, LPAR1, CTTN, PTK2B, GRB2, HCLS1, ICAM1, LIMK1, SMAD3, NTRK3, P2RX7, PFDN2, PFN2, PRKCE, PRKCQ, RAC1, RPS3, CLIP1, CCL21, SDC4, VIL1, WNT11, ARHGEF5, ITGB1BP1, PICK1, BAG4, ARPC5, ARPC1B, ACTR2, ARPC2, ABI2 |
1551 | GO:0036211 | 0.00 | 1.44 | 518.04 | 632 | 2192 | protein modification process | ABCA1, ABL1, ABL2, ABO, ACP1, ACTL6A, ACVR2B, ACVRL1, ADAM10, ADAR, ADH5, ADRA1B, AGTR2, ALK, ANG, ANGPT1, ANXA1, BIRC3, XIAP, BIRC5, APLP2, APP, ARAF, ARCN1, TRIM23, ARNT, ARR3, ARSA, STS, ARSD, ARSE, ARSF, ART1, ASL, ATP6AP1, ATR, AVPR2, AXL, BACH1, BARD1, BAX, OPN1SW, BCR, BGLAP, BHMT, BLK, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, BRCA2, BTK, BUB1B, TSPO, C3, CALM3, CAMK2A, CANX, CAV3, CBL, CBLB, CCNB1, CCNC, CCNE1, CCNF, CCNT2, CD3E, CD4, CD36, CD44, CD59, CDK11B, CDC20, CDC25A, CDC25C, CDC27, CDK2, CDK3, CDK4, CDK6, CDK8, CDKN1A, CENPE, CENPF, CHAD, CHEK1, CHRM1, CHRM3, CHUK, CKS1B, CLU, CLK1, CLK3, COPA, CREB1, CRH, CRKL, CRY2, CRYBA1, CSF1R, CSF2RB, CSNK1D, CSNK1G3, CSNK2A1, CSNK2A2, CSPG4, CTF1, CTGF, CTH, CTSH, DAD1, DAPK3, DCN, ACE, DLG2, DLG3, DYNC1H1, DNMT1, DNMT3B, DUSP1, DUSP5, E4F1, LPAR1, EDNRA, PHC2, EFNA1, EFNA5, EGR2, EPHA2, EIF5A, ELK1, EMP2, EP300, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, EYA4, ERCC3, ERCC6, ERG, EVPL, EXT2, EXTL1, EYA2, EZH1, F2, F2R, F7, F10, PTK2B, FANCF, FBLN1, EFEMP1, FGA, FGF3, FGF4, FGF7, FGFR3, FGR, FKBP3, FKBP5, FLT1, FLT3, FLT3LG, FLT4, FPR1, FSHR, FUT6, FUT8, FYB, FYN, GAD1, GAPDH, GCG, KAT2A, OPN1MW, GDF9, B4GALT1, GMDS, GNAQ, GNG3, GOLGA2, GOLGB1, GP1BA, GPLD1, GPX1, GRB2, RAPGEF1, GRIA1, GRIN2A, GRM1, GUCY2C, GUCY2F, GUCY2D, HIST1H1B, HCLS1, HGF, NRG1, HHEX, UBE2K, HLCS, HMBS, HMGCR, HNRNPC, HPX, HRC, HRG, HSF4, DNAJB2, HSPB1, HTR2C, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF1R, IGF2, IGFBP3, IL1A, IL2RA, IL12B, IL12RB2, IL13, IL18, ILK, INHA, INS, INSRR, IRAK1, IRAK2, ISL1, ITGA1, ITGA5, ITGAV, ITGB1, JARID2, JUN, KCNH2, KDR, KISS1, KIT, LIMK1, LIPE, LTF, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAN2B1, MARK3, MDH2, MGAT2, MGAT3, KITLG, ATXN3, MAP3K11, PPP1R12A, CNOT4, NTRK2, NTRK3, NUP98, OXTR, P2RX7, P4HA1, PRDX1, PAH, PAM, PCK1, PCNA, PCP4, PDK4, PEX12, CFP, PFN2, PHF2, PHKA2, PHKB, PHKG1, PIM1, PPIB, PPID, PPM1B, PPP2CB, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PPP4C, PPP5C, PPP6C, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRKCI, PRKD1, PRKCQ, PRKCSH, PRKX, PROC, PSAP, PSKH1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, PTPN4, PTPN6, PTPN7, PTPRA, PTPRE, PTPRH, PTPRJ, PTPRN, PTPRN2, PTPRR, PTPRS, RAB1A, RAB3B, RAB6A, RABGGTA, RABGGTB, RAC1, RAC2, RAD21, RAD51, RAF1, RAG1, RAG2, RANBP2, RANGAP1, RAP2A, RAP2B, RARA, RASA2, RB1, RBBP6, RBM4, OPN1LW, REST, RGR, RNF6, RPS3, RPS6KA1, RPS6KB1, RPS6KB2, RYK, S100A7, S100A8, S100A9, S100A12, SALL1, SATB1, SBF1, CCL21, CCL22, CCL25, XCL1, CX3CL1, SDC4, TRAPPC2, SET, SETMAR, SFPQ, SGK1, SHC1, SHMT2, STIL, SKP1, SUMO3, SNCA, SOX9, SP100, UAP1, SPINK1, SPRR2A, SPRR2D, SPRR2E, SPRR2G, SPRR3, SREBF1, SRPK2, TRIM21, STAT4, STK10, STYX, XCL2, ADAM17, TAF7, TAF10, TBL1X, NR2F2, TNFRSF1A, TNFRSF1B, TOP1, TOP2A, TOP2B, TP73, TPD52L1, NR2C2, HSP90B1, TRAF2, TSC1, TSG101, TTC3, TTK, TYRO3, UBB, UBA7, UBE2D2, UBE2E2, UBE2H, UBE2L3, UBE3A, SUMO1, USP4, KDM6A, UTY, UVRAG, VEGFB, VRK1, VTN, WFS1, WNT1, WNT11, TRIM25, ZNF207, PRDM2, RNF103, FZD5, SCG2, AIMP2, ARHGEF5, TUSC3, NUP214, FGF23, AAAS, CDK2AP1, GAN, AKAP1, USP11, USP9X, KDM5C, SMC1A, USP9Y, HIST1H4I, BAP1, FZD4, FZD7, FZD8, GFI1B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, BCAR3, DYRK2, CUL4A, CUL3, CUL2, CUL1, TPST2, TPST1, FKBP6, OGT, PPM1D, IKBKG, IKBKAP, HAT1, COPS3, CDC14B, STK16, RUVBL1, USO1, PDE5A, DYNLL1, PEA15, GALNT4, CDC23, B4GALT4, B4GALT3, B3GALT2, EED, RIPK1, RIPK2, RIOK3, TNFRSF18, TNFRSF10B, TNFRSF10A, DYRK4, CDKL1, DPM2, NRP1, PROZ, CDC16, HERC2, P4HA2, RPS6KA4, TNFSF18, CDKL2, SOCS3, RNF8, BAZ1B, UBA3, DIRAS3, UNC119, USP14, USP2, USP8, RGN, LATS1, SMC3, DYRK1B, CTDP1, ARHGEF2, ZW10, AURKB, VAPB, STK17B, STK17A, ITGB1BP1, COPB2, GPR55, SOCS6, KLF4, COPS2, GTF3C4, B4GALT6, SLIT2, UBE4A, SLC9A3R1, COG1, EIF2AK3, PICK1, AKAP6, ATG5, PIGL, PSMF1, GDF15, GOSR1, TMEM59, BAG5, BAG4, NRG2, SEC22B, GOSR2, CLOCK, CDC42BPB, RNF14, RNF7, TRAF4, AATK, NUP155, TTLL4, KDM4A, NUP93, UBE3C, RAPGEF2, SETD1A, SLK, ATG13, DLGAP5, SPOCK2, RNF40, CUL7, RB1CC1, DNAJC6, ZEB2, NUAK1, KLHL21, RNF10, OXSR1, USP3, TNFSF15, NR1H4, RBX1, HDAC6, GNE, PIGK, SH2D3C, SH2D3A, RANBP9, UBA2, SAE1, COL4A3BP, SGK2, RAD50, FEM1B, AKAP9, ABI2, RASA4, ATP6AP2, FARP1, CHST4, RNF41, PSME3, PSMD14, CTDSPL, SPRY1 |
1552 | GO:0019953 | 0.00 | 1.44 | 97.13 | 125 | 411 | sexual reproduction | ABAT, NR0B1, ANG, ANGPT2, BIRC3, APLP2, APP, ARNTL, ATRX, AXL, BAD, BAX, BBS4, BCL2L1, PRDM1, BMP4, BRCA2, BRDT, CCNB1, CD9, CDC25C, CNR1, CXADR, CYLC1, CYLC2, DAZ1, ACE, DIAPH2, DNM2, DRD5, EDNRA, PHC2, ETV5, PTK2B, FANCF, FANCG, FSHB, FSHR, GATA4, GDF9, B4GALT1, GLRA1, HIST1H1T, HIST1H1A, HEXB, HOXD9, HOXD10, HPGD, IGF1, IHH, IL1R1, IL12B, ING2, ITGB1, KIT, KRT9, SMAD1, SMCP, ODF1, OVGP1, OVOL1, OXTR, P2RX1, P2RY2, SERPINA5, PGR, PPP2R1A, PRKACG, PRKAG1, PTEN, RAD23B, RAD51C, RARA, RPS6KB1, SBF1, SMARCA2, SMARCA4, SOX3, SOX9, SPAG4, SPAM1, SPINK1, STAT3, STYX, TAF4B, TBP, NR2F2, NR2C2, TRPC3, TSPY1, TYRO3, UBE3A, VIP, ZAN, EIF4H, YY1, ZNF35, ZNF148, DNALI1, FOSL1, AAAS, NRIP1, USP9X, USP9Y, TPST2, FKBP6, DDO, RUVBL1, TP63, PDE5A, DYNLL1, EIF2S2, HERC2, RNF8, RGN, FAM50A, PICK1, ADAMTS2, TBPL1, CLOCK, SPAG6, SPATA2, REC8, BCL2L11, AKAP9 |
1553 | GO:0032989 | 0.01 | 1.44 | 53.31 | 69 | 231 | cellular component morphogenesis | ACTN1, ADD1, ANXA1, ATP2B2, AXL, BMP4, CASP9, CASQ1, CASQ2, CAV3, CD9, COL1A1, CLDN3, CRYGB, DAPK3, DIAPH1, LPAR1, EP300, ERG, F2, PTK2B, FBLN1, FGA, FGD1, FGR, GAS2, GP1BA, HEXB, HGF, FOXA2, ICAM1, IDUA, RBPJ, IHH, ITGA4, KDR, SMAD3, SMAD7, P2RX7, PALM, PRKAR1A, PTN, PTPN6, RAB1A, RAC3, RB1, S100A4, S100A13, SALL1, SNAI1, SOX9, SPARC, ST14, STC1, TAL1, TTC3, TYRO3, UPK3A, CLRN1, WNT11, FZD4, FZD7, ADAM15, LATS1, ARHGEF2, ZMYM6, ITGB1BP1, SLC9A3R1, TBPL1 |
1554 | GO:0048285 | 0.00 | 1.43 | 78.70 | 101 | 333 | organelle fission | ABL1, BIRC5, ATRX, BAX, BMP4, BRCA2, BRDT, BUB1B, CCNB1, CCNF, CCNG2, CD28, CDK11B, CDC20, CDC25A, CDC25C, CDC27, CDK2, CDK3, CENPE, CENPF, CHEK1, CSNK2A1, CSNK2A2, DAPK3, DCN, DRD3, DUSP1, E4F1, ERCC4, FGFR3, GOLGA2, GPR3, HGF, IGF1, IGF1R, IGF2, IL1A, ING2, INS, KDR, KIF25, PPP1R12A, NUMA1, OPA1, CHMP1A, PPP2R1A, PPP5C, PRKAR1A, PTEN, PEX19, RAD21, RAD51, RAD51C, RAD51B, RAD51D, RAN, RB1, RPL24, RPS3, CLIP1, SMARCA4, DYNLT3, DYNLT1, TOP2A, TOP2B, TTK, UBB, VRK1, XRCC2, ZNF207, NUP214, CLTCL1, USP9X, SMC1A, CUL3, FKBP6, RUVBL1, CDC23, PEX11A, CDC16, RNF8, LATS1, SMC3, CCNB2, CTDP1, ARHGEF2, ZW10, AURKB, KIF3B, RECQL5, MAD2L1BP, DLGAP5, CKAP5, CUL7, KLHL21, DCLRE1A, REC8, SMC4, ACTR2, RAD50 |
1555 | GO:0065008 | 0.00 | 1.43 | 113.00 | 145 | 537 | regulation of biological quality | ACVR2B, ALDH1A3, ARNTL, BCL2L1, BCR, BLK, BNIP3L, ZFP36L2, CHAT, AKR1C4, CHRNB4, CIRBP, CNGA1, CNP, CRHBP, CYP3A4, DAPK3, DPP6, ELAVL1, EP300, EYA2, FCER2, FGD1, FLOT2, GAD1, GAPDH, GAS2, KAT2A, GDF9, GLRA1, GLUD1, GPR26, GRID2, HIST1H1B, ISL1, JUN, KCNC2, KCND2, KCND3, KCNK2, KCNS3, KPNA1, KPNA2, KPNA3, KPNA4, SMAD3, YBX1, NUP98, PAH, PALM, PEX6, SERPINB9, SEPT5, PPIB, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTPRJ, PEX19, PYCR1, RAB1A, RBP1, REST, RFX3, RXRA, S100A12, S100A13, SCN1A, SCN2A, SCN8A, SET, SLC1A6, SLC6A13, SLC22A1, SLC22A3, SOX11, SRD5A1, TRIM21, SULT1E1, SYN1, SYT1, SYT4, SYT5, SERPINA7, TNFRSF1B, TNNC1, TYMS, SUMO1, SCGB1A1, UGT2B7, USP4, ZNF207, NUP214, AAAS, ANP32A, SYN3, FZD4, CNTNAP1, GAS7, DDO, KHSRP, AKR1C3, DYNLL1, STX11, DPM2, LIN7A, SYNJ1, ARHGEF7, SYT7, USP2, PCSK7, SNAP29, RAB9A, NRXN2, AKAP7, PSMF1, BAG3, CLOCK, SNCAIP, NUP155, NUP93, RIMS2, EIF4A3, PIEZO1, USP3, HDAC6, ATP9A, DHRS9, PSME3, DHRS2, PSMD14 |
1556 | GO:0044700 | 0.00 | 1.42 | 372.41 | 455 | 1791 | single organism signaling | ABCA1, ABCA4, ACTB, ACTL6A, ADD1, APLNR, ANGPT2, ANXA6, BIRC5, APLP2, APP, KLK3, TRIM23, ARF5, ARHGDIB, ARL1, ARR3, ATF4, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATRX, AVPR1B, AVPR2, ADGRB2, BBS4, BCL2A1, BCL3, TNFRSF17, OPN1SW, BCR, BNIP3L, BOK, DST, BRCA2, BSG, BTK, BUB1B, CAPN5, DAGLA, CASP9, KRIT1, CCNC, CCNE1, CCNT2, CD3D, CD3G, CD5, CD6, CD7, CD9, TNFRSF8, CD37, ENTPD2, CD59, CD72, CD151, CDA, CDC25C, CDH1, CDH6, CDK2, CDK4, CDK6, CDK8, CDKN1A, CENPA, CENPE, CENPF, AKR1C4, CLCN6, TPP1, CLPS, CCR3, CCR8, CNGA1, COL4A3, COL15A1, CLDN3, CR2, CSH1, CSNK1G3, CSNK2A2, CTLA4, CTSK, DGKB, DCC, DIAPH1, DIAPH2, DMBT1, DOK1, RCAN1, EIF4A1, EIF4E, EIF4G2, ELK1, EP300, EPHB1, EPHB2, EPHB3, ERG, ESRRG, EXT2, EXTL3, EYA2, F2RL2, EFEMP1, FCER2, FCGRT, GPC4, FGD1, FLT3LG, FPR3, FSHB, CENPI, NR5A2, FUT8, FYB, GABRE, GAS1, GCGR, OPN1MW, GDI1, GDI2, GFRA1, B4GALT1, GH2, GMDS, GNA15, GNAQ, GNAT1, GNAT2, GNRH2, GNRHR, GPR3, GPR4, XCR1, GPR15, GPR17, GPR19, LPAR4, GPR26, GRID1, CXCL3, GRPR, GTF2I, GUCA1A, GUCY2C, GUCY2F, GUCY2D, HDGF, HIP1, HIVEP2, NR4A1, HNF4G, HPGD, ICAM2, IFI16, SP110, IFIT1, IFIT3, IFNA5, IFNA13, IFNA17, IFNA21, IFNGR1, IFNW1, IL1R1, IL1RAP, IL10RA, IL12RB2, IL13RA2, IL15RA, INPP1, INSIG1, INSRR, IRF1, IRF5, ISG20, ITGA4, ITGA9, ITGAD, ITGAM, CD82, KLRC3, KPNA1, KPNA2, KPNA3, KPNA4, LIMK1, LLGL2, LTBP2, SMAD1, SMAD9, SCGB2A1, MGAT3, CIITA, FOXO4, PPP1R12A, PPP1R12B, NUP98, OAS3, OR1F1, OR2C1, OTX2, P2RY2, P2RY4, P2RY6, PRDX1, PDE4B, PDE8A, PDK4, PENK, PF4V1, PIK3C2B, PIM1, PI4KA, PPP2R5D, PPP4C, PRCP, PRKAG1, PRKCI, PRKCSH, PTAFR, PTGDR, PTGER1, PTGER2, PTH2R, RAB4A, RAB5B, RAB6A, RAB27A, RABIF, RAC2, RALA, RAN, RANBP1, RANBP2, RANGAP1, RAP1GAP, RAP2A, RAP2B, RARB, RBM4, RBP1, RBP2, OPN1LW, RCVRN, PRPH2, DPF2, RGR, RIT1, RNF6, RPS6, RPS6KB2, RPS19, RPS27, CLIP1, RSU1, RXRA, RXRG, S100A1, SORT1, S100A11, TSPAN31, SCTR, SDC4, SELE, SEMA3F, SGK1, STIL, SIPA1, SKP1, SP1, SP100, SPARC, SPOCK1, SRPK2, TRIM21, STAT2, STAT4, STAT5B, STAT6, STK10, STRN, STYX, SULT1A3, TACR3, TAF7, TBL1X, DYNLT1, NR2F1, NR2F2, TSPAN7, NR2C2, HSP90B1, TRAF1, TRHR, TRPC3, TSG101, TUFT1, TNFSF4, TYROBP, UBA7, UBE2D2, SUMO1, UPK1B, SCGB1A1, KDM6A, VAV1, VIL1, VIM, TRPV1, LAT2, XPA, ZIC1, ZBTB17, ZNF217, IL1R2, NUP214, AAAS, ANP32A, RND2, MADCAM1, NRIP1, CLTCL1, USP9X, SMC1A, USP9Y, HIST1H4I, FZD9, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, OR1A1, OR1D5, OR1G1, OR3A3, SPARCL1, BCAR3, NSMAF, DYRK2, CUL4A, CUL2, CUL1, SORBS2, OGT, PIK3R3, IKBKAP, COPS3, UNC5C, SSNA1, EIF4G3, S1PR4, CTNNAL1, ADAM15, TNFRSF10D, PEX11A, INPP4B, NRP2, TAX1BP1, HIST1H3F, RPS6KA4, CDKL2, BAZ1B, TAAR5, UBA3, DOK2, ANGPTL1, DIRAS3, USP8, RGN, ATP6V0D1, SMC3, ARHGEF1, RASSF9, ZW10, REPS2, AURKB, VAPB, STK17B, STK17A, BCL7B, TAAR2, COPS2, TRIP10, GLP2R, RAB33A, RAB9A, ARHGAP29, AKAP7, IL27RA, BAG3, ATP6V1G1, BCAR1, GTPBP1, GOSR2, CDC42BPB, RNF14, RAB36, AATK, GUCA1C, GNA14, FEZ2, RALGPS1, ZNF516, SDC3, NUP93, SEMA3E, IFT140, ARHGAP32, SLK, ZFYVE16, SNX17, CKAP5, TATDN2, SPOCK2, KIAA0141, CUL7, ARHGEF11, GAB2, C2CD5, TRIL, RHOBTB1, NUAK1, P2RY14, ARHGAP25, OXSR1, NR1I3, NR1D2, CASP8AP2, NR2E3, ZBTB33, COL4A3BP, ARPC5, ARPC1B, ACTR2, ARPC2, SGK2, FEM1B, ARL4A, ARFRP1, ABI2, FARP1, WASF2, RNF41, RCAN2 |
1557 | GO:0065003 | 0.04 | 1.41 | 34.30 | 44 | 151 | macromolecular complex assembly | ABCA1, ADAR, ATR, BICD1, CIRBP, CLNS1A, DDX1, DDX6, DYNC1H1, GRB7, EIF3E, LCAT, CNOT2, RAD51C, RAD51B, RAD51D, RB1, RPL3, RPL3L, RPL5, RPL10, RPL24, RPL38, RPS27, SRSF1, SRSF5, SFSWAP, SNRPC, SNRPD1, SNRPE, SNRPF, SRPK2, TAF7, USP4, NR1H2, XRCC2, PRPF18, EIF3G, SRSF9, DGAT1, TAF1B, PRPF3, SCAF11, DDX23 |
1558 | GO:0043085 | 0.00 | 1.41 | 99.10 | 126 | 435 | positive regulation of catalytic activity | AMPH, APAF1, APOH, APP, TRIM23, ARF1, ARHGAP4, ARHGAP6, ARHGDIB, ARL1, AVPR1B, BCR, BOK, CASP9, RCBTB2, CHN1, CHN2, CLPS, COL4A3, CREB1, CTGF, CTSH, DNM2, S1PR1, EIF2B1, EPHA2, F3, FBLN1, FGD1, GCGR, GDI1, GDI2, GM2A, GNA15, GNAQ, GNAT1, GPLD1, FFAR1, HIP1, HSPB2, ICAM1, IFI16, IGFBP3, ITGB1, ITPR1, JUN, LLGL2, SMAD3, PPP1R12A, PPP1R12B, P2RX1, PCNA, PCOLCE, PFN2, PRKCE, PRKD1, PSAP, PTAFR, RAB4A, RABIF, RANBP1, RANGAP1, RAP1GAP, REST, RGS10, RGS12, RGS13, RPGR, RSU1, RYR2, S100A8, S100A9, SBF1, CCL22, CCL25, XCL1, CX3CL1, SELE, SETMAR, SFTPB, SIPA1, SOS2, XCL2, TBCD, TSC1, SUMO1, NR1H2, VAV1, PICALM, BCAR3, NSMAF, OGT, RGS20, S1PR4, TRADD, CRADD, TNFSF10, ARHGEF7, EIF2B3, EIF2B2, HERC2, RABEP1, ARHGEF1, ARHGEF2, GPR55, TRIP10, GTF3C4, ARHGAP29, EIF2AK3, AKAP6, RIN1, RALGPS1, ARHGAP32, ACAP1, ARHGEF11, SGSM2, ARHGAP25, CASP8AP2, PDCD6, BCL2L11, SH2D3C, SH2D3A, UBA2, SAE1, FARP1, DENND4A |
1559 | GO:0007154 | 0.00 | 1.41 | 317.12 | 388 | 1546 | cell communication | ABCA4, ACTB, ADD1, APLNR, ANG, ANGPT2, ANXA6, KLK3, TRIM23, ARF5, ARL1, ARR3, ATP1A1, ATP1A3, ATP2A1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATRX, AVPR1B, AVPR2, ADGRB2, BBS4, BCL2A1, TNFRSF17, OPN1SW, BOK, DST, BRCA2, BSG, BTK, BUB1B, CAPN5, DAGLA, CASP9, CASQ1, KRIT1, CCNC, CCNT2, CD3D, CD3G, CD5, CD6, CD7, CD9, TNFRSF8, CD37, ENTPD2, CD59, CD72, CD151, CDA, CDC25C, CDH1, CDH6, CDK2, CDK4, CDK6, CDK8, CENPA, CENPE, CENPF, AKR1C4, CLCN6, TPP1, CLPS, CCR3, CCR8, COL4A3, COL15A1, CLDN3, CR2, CSH1, CSNK1G3, CTLA4, DGKB, DCC, DIAPH1, DIAPH2, DMBT1, DOK1, DPP6, S1PR1, EIF4A1, EIF4E, EIF4G2, ELK1, EPHB2, EPHB3, ERG, ESRRG, EXT2, EXTL3, EYA2, F2RL2, EFEMP1, FCER2, FCGRT, GPC4, FLT3LG, FPR3, FSHB, CENPI, NR5A2, FUT8, FYB, GABRE, GCGR, OPN1MW, GFRA1, B4GALT1, GH2, GMDS, GNA15, GNAQ, GNAT2, GNRH2, GNRHR, GPR3, GPR4, XCR1, GPR15, GPR17, GPR19, LPAR4, GPR26, GRID1, CXCL3, GRPR, GTF2I, GUCY2C, HDGF, HIP1, HIVEP2, NR4A1, HNF4G, HPGD, ICAM2, SP110, IFIT1, IFIT3, IL1R1, IL1RAP, IL10RA, IL12RB2, IL13RA2, IL15RA, INPP1, INSIG1, INSRR, IRF5, ISG20, ITGA4, ITGA9, ITGAD, ITGAM, CD82, KLRC3, KPNA1, KPNA2, KPNA3, KPNA4, LIMK1, LTBP2, SMAD1, SMAD9, SCGB2A1, MGAT3, CIITA, FOXO4, PPP1R12A, PPP1R12B, NRCAM, NUP98, OAS3, OR1F1, OR2C1, P2RY2, P2RY4, P2RY6, PDE4B, PDE8A, PF4V1, PIK3C2B, PI4KA, PPP2R5D, PPP4C, PRKAG1, PRKCI, PRKCSH, PTAFR, PTGDR, PTGER1, PTGER2, PTH2R, RAB4A, RAB5B, RAB6A, RAB27A, RABIF, RALA, RAN, RANBP1, RANBP2, RANGAP1, RAP2B, RARB, RBM4, RBP1, RBP2, OPN1LW, PRPH2, DPF2, RGR, RIT1, RPS6, RPS6KB2, RPS19, RPS27, CLIP1, RSU1, RXRA, RXRG, RYR1, S100A1, SORT1, S100A11, TSPAN31, SCN1A, SCN2A, SCN7A, SCN8A, SCTR, SDC4, SELE, SEMA3F, SGK1, STIL, SKP1, SP1, SPARC, SPOCK1, SRPK2, TRIM21, STAT4, STAT5B, STAT6, STK10, STRN, SULT1A3, TACR3, TAF7, TBL1X, NR2F1, NR2F2, TSPAN7, NR2C2, HSP90B1, TRHR, TRPC3, TUFT1, TNFSF4, TYROBP, UBA7, UBE2D2, UPK1B, SCGB1A1, KDM6A, VIL1, VIM, TRPV1, LAT2, XPA, ZNF217, IL1R2, NUP214, AAAS, ANP32A, RND2, MADCAM1, NRIP1, CLTCL1, USP9X, SMC1A, USP9Y, HIST1H4I, FZD9, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, OR1A1, OR1D5, OR1G1, OR3A3, SPARCL1, BCAR3, NSMAF, DYRK2, CUL4A, CUL2, CUL1, SORBS2, PIK3R3, IKBKAP, COPS3, UNC5C, SSNA1, EIF4G3, S1PR4, CTNNAL1, ADAM15, TNFRSF10D, PEX11A, NRP2, HIST1H3F, RPS6KA4, CDKL2, TAAR5, UBA3, DOK2, ANGPTL1, DIRAS3, USP8, ATP6V0D1, SMC3, RASSF9, ZW10, REPS2, AURKB, VAPB, STK17B, STK17A, BCL7B, TAAR2, COPS2, GLP2R, RAB9A, AKAP7, IL27RA, BAG3, ATP6V1G1, BCAR1, GTPBP1, GOSR2, CDC42BPB, RAB36, AATK, GNA14, ZNF516, SDC3, NUP93, SEMA3E, SLK, ZFYVE16, SNX17, CKAP5, TATDN2, SPOCK2, KIAA0141, CUL7, GAB2, C2CD5, TRIL, NUAK1, P2RY14, OXSR1, NR1I3, NR1D2, CASP8AP2, NR2E3, ZBTB33, COL4A3BP, ARPC5, ARPC1B, ACTR2, ARPC2, SGK2, ARL4A, ARFRP1, ABI2, WASF2 |
1560 | GO:0015849 | 0.03 | 1.41 | 42.30 | 54 | 179 | organic acid transport | ABAT, ACACB, AGTR2, ALB, ABCD1, ANXA1, ARG1, ATP1A2, CACNA1A, CACNB4, CD36, AKR1C4, CPT1B, CPT2, CTNS, ACE, DRD3, GOT2, KCNJ10, NTRK2, NTSR1, P2RX4, P2RX7, P2RY2, ABCD3, RXRA, SLC1A6, SLC6A6, SLC6A7, SLC6A13, SLC7A1, SLC7A4, SLC10A1, SLCO2A1, SLCO1A2, SLC22A5, SNAP25, SNCA, SYT1, TRPC4, TRPV1, SLC7A5, SLC10A3, SLC25A12, SLC5A6, SLC13A2, SLC16A6, SLC16A5, SLC6A5, SLC9A3R1, NR1H4, SLC25A13, SLC25A15, ABCC4 |
1561 | GO:0045893 | 0.04 | 1.40 | 34.42 | 44 | 151 | positive regulation of transcription, DNA-templated | AGTR2, BRCA2, BRDT, CCNE1, CD86, CDH1, CDK2, CDX2, CHEK1, COL1A1, DNM2, ERCC6, F2R, FGF7, HMGN1, HNF4G, IFNA2, ILK, ING2, AFF1, PHF2, RAN, RFXAP, RNF6, SMARCA1, SMARCD3, SNAI1, SRY, TBP, NR2F2, TNNI2, WNT11, ZBTB17, ZXDA, FGF23, PICALM, FZD7, KLF7, BAZ1B, DYRK1B, RNF14, ZNF516, ARHGEF11, NR1D2 |
1562 | GO:0048863 | 0.04 | 1.40 | 35.35 | 45 | 150 | stem cell differentiation | BMP4, BMPR1A, ZFP36L2, RUNX2, COL1A1, EDNRA, EFNA1, EFNB1, ELAVL1, ERG, ETV4, GATA4, GATA6, GPM6A, HGF, NRG1, HHEX, FOXA2, RBPJ, ISL1, JARID2, KIT, SMAD3, SMAD7, KITLG, FOXO4, CNOT2, NTF4, PAX3, REST, S100A4, SEMA3F, SNAI1, SOX9, SOX10, SOX11, WNT11, SEMA3B, TP63, ADAM15, NRP1, PHOX2B, SEMA3E, CUL7, ZEB2 |
1563 | GO:0065007 | 0.00 | 1.39 | 871.55 | 961 | 4233 | biological regulation | ACPP, ACTG2, ACTL6A, ADAM10, AEBP1, NR0B1, AK1, ALK, ALOX15B, ALX3, AMPH, ANXA3, APAF1, BIRC3, BIRC5, KLK3, ARAF, TRIM23, ARF5, ARG1, ARHGAP6, ARHGDIB, ARL1, PHOX2A, ARR3, STS, ASCL1, ASCL2, ASIP, ASS1, ATF4, RERE, FXYD2, BACH1, BCHE, BCL2A1, OPN1SW, BHMT, BICD1, PRDM1, BMI1, BMP1, BMP3, BMP8B, BMPR1A, BOK, DST, BPI, BRCA2, BRDT, BST2, KLF9, KLF5, BTF3, BTK, BUB1B, CAPN5, C7, CAPN1, CAPN6, CASP5, CASP9, CAT, RUNX2, CBL, CBLB, CCNB1, CCNC, CCNE1, CCNF, CCNG2, CCNT2, CD3D, CD3E, CD3G, CD5, CD6, CD8A, CD28, CD86, TNFRSF8, TNFSF8, CD37, CD70, CD72, ADGRE5, CD151, CDA, CDK11B, CDC25A, CDC25C, CDC27, CDH1, CDH6, CDH15, CDK3, CDK8, CDKN1A, CDX2, CEBPE, CENPA, CENPB, CENPF, CHAD, RCBTB2, CHD2, CHD4, CHEK1, CHN1, CHN2, CKS1B, AP1S1, AP2S1, CLC, CLCN7, CLCNKA, CLCNKB, CLK1, CLK3, CLPS, CNN1, CNN2, CNN3, COL4A3, COL6A3, COL15A1, COMP, COX8A, CLDN3, CR2, CRKL, CRX, CRYBA1, CSF2RB, CSH1, CSNK1D, CSNK1G3, CSNK2A1, CSNK2A2, CSPG4, CST6, CTF1, CTH, CTLA4, CTNNA1, DAD1, DAZ1, BRINP1, DDX1, DDX5, DDX6, DFFA, DHCR7, DHFR, DIAPH2, DLG2, DLG3, DLX5, DMBT1, DNM1, DNMT1, DNMT3B, DOK1, DPEP1, DPP4, DPYSL3, ARID3A, RCAN1, DTNA, DUSP1, DUSP5, E2F6, E4F1, EBF1, ECM1, EDA, EFNA1, EFNA3, EFNA4, EFNB1, EGR3, EGR4, EIF2B1, EPHA2, EIF4A1, EIF4E, EIF4G2, EIF5, EIF5A, SERPINB1, ELAVL2, ELK1, EMX2, EN1, EPB41, EPHA8, EPRS, EPS15, EYA4, ERCC3, ERF, ERG, ESRRG, ETV3, ETV4, ETV6, EVX1, EWSR1, EXT2, EXTL3, EZH1, FABP7, FBLN2, EFEMP1, FCGRT, FCN2, GPC4, FGF3, FGF4, FGFR3, FLT1, FLT3LG, FLT4, AFF2, FPR1, FPR3, CENPI, FSHR, FUT8, FYB, FZD2, GABRA4, GABRA5, GABRE, GABRG1, GABRR1, GABRR2, GAS1, OPN1MW, GDI1, GDI2, GFRA1, B4GALT1, GH2, GPC3, GMDS, GNAT1, GNG10, GNGT1, GNGT2, GNRH2, GNRHR, GOLGA2, GPM6A, GPR1, GPR3, GPR4, GPR15, GPR17, GPR19, LPAR4, RAPGEF1, GRIA4, GRID1, CXCL3, GRPR, GSC2, GTF3A, BRF1, GUCA1A, GUCA2A, GUCY2C, GUCY2F, GUCY2D, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H2AD, HBA2, HDGF, CFHR1, HHEX, HIC1, HIP1, HIVEP2, HLF, HMGN1, HMGA1, NR4A1, HMX2, HNF4G, ONECUT1, HNMT, HOXC10, HOXC11, HOXD8, HOXD9, HOXD10, HOXD12, HP, HPGD, HPRT1, HSF4, DNAJB2, HSPA9, HSPB2, ICAM2, ICAM4, IDH1, IFI16, SP110, IFIT3, IFNGR1, IFNW1, IGFBP3, IGFBP6, RBPJ, IL1RAP, IL10RA, IL12B, IL12RB2, IL13RA2, IL15RA, IL18, IDO1, ING2, INPP1, INPPL1, INSIG1, INSRR, EIF3E, IRAK1, IRAK2, IRF5, ISG20, ITGA9, ITGAD, ITIH1, ITIH4, JARID2, JUND, CD82, KCNA3, KCNA4, KCNJ3, KCNJ6, KCNJ9, KCNJ14, KCNJ16, KCNS2, KLRC3, KIF25, IPO5, LAMA3, LAMA4, LLGL2, LRPAP1, LTBP2, CAPRIN1, SMAD6, SMAD9, MAL, MARK3, MAZ, MEOX2, SCGB2A1, MGAT3, MGMT, CIITA, ATXN3, MAP3K11, AFF1, FOXO4, CD200, PPP1R12A, PPP1R12B, CNOT2, NTF4, NTHL1, NTN3, NVL, OAS3, OAZ1, OAZ2, OMD, OMP, OPA1, OR1F1, OR2C1, ORC1, ORC2, ORM2, OSBP, OTX1, OTX2, OVGP1, OVOL1, P2RY6, P2RY11, PA2G4, PAEP, PAX3, PAX9, PCBP2, PCM1, PCOLCE, CHMP1A, PCP4, PDE8A, PDYN, PENK, PEX13, CFP, PFDN2, PGAM1, PGR, PHF2, SERPINA4, SERPINB5, SERPINB13, SERPINI2, PIK3C2B, PIM1, PI4KA, PIP4K2A, FXYD3, PPID, PPM1B, PPP1R8, PPP2CB, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PPP4C, PPP5C, PRCC, PRG2, PRKAG1, PRKCI, PRKCSH, PRKX, PRPSAP1, PTGDR, PTGER1, PTGER2, PTGIS, PTH2R, PTPRA, PTPRE, PTPRR, PURA, PVR, PEX5, PZP, RAB4A, RAB5B, RAB6A, RABIF, RAD21, RAD23B, RALA, RAN, RANBP1, RANGAP1, RAP1GAP, RAP2A, RARB, RASA2, RBBP6, RBL2, RBM4, RBP2, OPN1LW, RCVRN, PRPH2, REG1A, DPF2, RFNG, RFX1, RFXAP, RGR, RGS10, RGS12, RGS13, RHEB, RIT1, RLF, RNASE2, RPGR, RPL24, RPL38, RPS3, RPS3A, RPS6KA1, RPS6KB1, RPS6KB2, RPS27, RRM2, CLIP1, RSU1, RTN2, RXRG, RYK, S100A1, SORT1, S100A4, S100A11, SALL1, TSPAN31, SATB1, SBF1, SERPINB4, SCTR, CCL22, CCL25, CXCL6, CXCL5, SDC4, SEC14L1, TRAPPC2, SETMAR, SFPQ, SFRP5, SRSF5, SRSF7, SFSWAP, SFTPB, SH3BGR, SH3BGRL, SH3BP2, SHB, SHMT2, STIL, SIM2, SIPA1, SIX3, SKP1, SLC20A1, SLPI, SMARCA1, SMARCA2, SMARCD3, SMARCE1, SUMO3, SNAI1, SNAPC3, SNCB, FSCN1, SNRNP70, SNRPD1, SOX3, SOX10, SPIB, SPINK1, SPOCK1, SRP9, SRPK2, SRY, SSRP1, STAT2, STAT4, STAT6, STK10, STRN, STXBP2, STYX, SULT1A3, SUPV3L1, SURF4, XCL2, TACC1, TAF4B, TAF7, TAF10, TBCD, TBL1X, TBP, ZNF354A, DYNLT3, NR2F1, NR2F2, KLF10, TSPAN7, TMPO, CLEC3B, TNNC2, TNFRSF1A, TNNI2, TOP1, TOP2A, TOP2B, TPD52L1, TPM2, NR2C1, NR2C2, TRAF1, TRAF2, TRHR, TSN, TSG101, DNAJC7, TTC3, TTF1, TTK, TUFT1, TULP3, TNFSF4, TYROBP, UBA7, UBE2D2, UBE2E2, UBE2L3, UBE3A, UPK1B, UCP1, UNG, KDM6A, UTY, VDAC2, VIM, VIPR2, EIF4H, LAT2, WNT1, WNT11, XPA, XRCC2, YY1, ZFP37, ZFPL1, ZIC1, ZNF3, ZNF7, CNBP, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF91, ZNF99, ZNF124, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, RNF112, ZNF180, ZNF189, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZXDA, PRDM2, IL1R2, FZD5, SCG2, KCNAB1, AIMP2, ARHGEF5, SHOC2, PDHX, FOSL1, CDK2AP1, MADCAM1, ZNF239, DPF1, CHAF1B, CLTCL1, USP9X, KDM5C, SMC1A, USP9Y, BAP1, FZD7, FZD8, FZD9, GFI1B, HIST1H2AK, HIST2H2AC, OR1A1, OR1D5, OR1G1, OR3A3, SOX14, SPARCL1, UXT, BCAR3, ZNF282, NSMAF, DYRK2, CUL4A, CUL3, CUL2, CUL1, ATRN, TPST2, KLF11, SMARCA5, FKBP6, SORBS2, PPM1D, PIK3R3, IKBKAP, HAT1, COPS3, API5, PIR, BLZF1, CDC14B, STK16, RGS20, RUVBL1, KLF7, UNC5C, SSNA1, EIF4EBP3, PTCH2, CHRD, NUMB, DDX3Y, EIF3G, EIF4G3, PEA15, SRSF9, CDC23, SERPINB7, TRADD, EED, CTNNAL1, RIPK1, CRADD, HRK, TNFSF10, TNFSF9, ADAM15, RIPK2, TNFRSF18, DLK1, TNFRSF10D, TNFRSF10B, TNFRSF10A, CDKL1, SAP30, HESX1, NRP2, WISP3, PER3, CDC16, TAX1BP1, EIF2B3, EIF2B2, BUD31, AP1M1, HERC2, PHOX2B, HIST1H2AG, RPS6KA4, TNFSF18, CDKL2, TAF1B, TAF1A, SOCS3, RNF8, BAZ1B, TAAR5, UBA3, ANGPTL1, DIRAS3, UNC119, USP14, USP8, PDLIM1, SMC3, RABEP1, ARHGEF1, CBFA2T2, SYNGR3, DYRK1B, CTDP1, IL1RL1, ARHGEF2, RASSF9, ZW10, REPS2, DDX21, KCNAB3, ZMYM6, CCPG1, PDLIM7, STK17B, STK17A, BCL7B, TAAR2, SOCS6, ZNF235, KLF4, COPS2, TRIP11, TRIP10, GTF3C4, GLP2R, RAB33A, ZFYVE9, RECQL5, GRAP2, ZRANB2, ARHGAP29, HAND1, ZNF264, FHL5, IL27RA, ONECUT2, ADAMTS3, LITAF, GDF15, TBPL1, GOSR1, TMEM59, BAG5, ZNF254, NRG2, APBA3, CXCL14, SEC22B, GTPBP1, GABBR2, GOSR2, CDC42BPB, SOX13, RBM39, MAD2L1BP, AKAP12, RNF14, RAB36, TRAF4, GUCA1C, FEZ2, RALGPS1, ZNF516, EIF5B, SDC3, KDM4A, VGLL4, BZW1, DHX34, ST18, ADAMTSL2, ZNF646, SETD1A, IFT140, ARHGAP32, ACAP1, SLK, PHACTR2, ZFYVE16, ATG13, SNX17, DLGAP5, CKAP5, PHYHIP, TATDN2, SPOCK2, RNF40, KIAA0141, CUL7, ARHGEF11, DNAJC6, ZEB2, ZBTB24, GAB2, C2CD5, ZNF518A, EPM2AIP1, KIAA0319, TRIL, RHOBTB1, SMG7, NUAK1, SNAP91, KLHL21, RBM19, SGSM2, FAM20B, RNF10, ZBTB5, P2RY14, ARHGAP25, RBM8A, DLEC1, OXSR1, TNFSF15, NR1I3, RBX1, FGFBP1, DMTF1, CASP8AP2, NR2E3, ZBTB33, PDCD6IP, PDCD6, FRAT1, SH2D3C, SH2D3A, RANBP9, AP1M2, UBA2, SAE1, ABCC9, IL18BP, PDCD7, FEM1B, ARL4A, ZNF263, TRAP1, ARFRP1, G3BP1, RASA4, FARP1, WASF2, ZNF256, RNF41, NUTF2, EIF1, OLIG2, PRG4, CTDSPL, CD96, RCAN2, SPRY1, STAM2, DENND4A, RAMP3 |
1564 | GO:0044765 | 0.00 | 1.38 | 281.27 | 344 | 1273 | single-organism transport | ABCA3, ABCB7, ABCA4, ACTB, ACTL6A, ADD1, AMPH, ANXA6, ANXA11, APOH, ARCN1, ARL1, ATF4, FXYD2, ATP2A1, ATP2B1, ATP2B3, KIF1A, BARD1, BAX, BBS4, BCL2A1, BCL2L1, BGLAP, BICD1, BNIP3L, BSG, C3, VPS51, CA4, CASQ1, CASQ2, CD3G, CD4, SCARB2, CD59, CDK2, CDX2, CEBPE, AP1S1, CLCA1, CLCN3, CLCN6, CLCN7, CLCNKA, CLCNKB, CLNS1A, CNGA1, CNP, CRY2, CSNK1D, CSNK2A2, CTSK, CXADR, DIAPH1, DYNC1H1, DPP6, TSC22D3, EGR2, EIF4E, EIF5A, EMP2, EPS15, EYA2, F2, F7, F10, PTK2B, FAU, FCGRT, FCN2, FTL, FYN, G6PC, GABRA4, GABRA5, GABRE, GABRG1, GABRR1, GABRR2, GAS1, KAT2A, GDI1, GFER, GIF, GJA3, GJA4, GJB1, GPC3, GLE1, GM2A, GOLGA2, GOLGA4, GOLGB1, GPM6A, XCR1, GPR26, GRIA4, GRID1, GRID2, GRIN2A, HBA2, HBD, HBE1, HHEX, HNMT, HPX, HRC, HSPA9, ICAM1, INSIG1, ITGAV, KCNA1, KCNA3, KCNA4, KCND2, KCND3, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ6, KCNJ8, KCNJ9, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNS2, KIF5A, LIMK1, LTF, MAL, MYO1B, OAZ1, OAZ2, OPA1, P2RX3, P2RX5, P2RY4, P2RY6, PALM, SERPINA5, PCM1, CHMP1A, PDE4B, FXYD3, PLN, PPP6C, PRKAA1, PRKD1, PROC, PTEN, PTK2, PTPN6, ABCD4, RAB5B, RAB6A, RAC1, RANGAP1, RAP1GAP, RARA, RCVRN, UPF1, RHAG, RHCE, RHD, RNASE2, RPGR, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS6KB1, RPS11, RPS19, RPS20, RPS27, CLIP1, RTN2, RYR1, RYR2, S100A1, SORT1, SCN1A, SCN2A, SCN4B, SCN5A, SCN7A, SCN8A, SCNN1A, SCNN1B, SCNN1G, SCO1, CCL21, XCL1, TRAPPC2, SRSF1, SRSF5, SRSF7, SFTPD, SLC2A3, SLC2A4, SLC2A5, SLC4A1, SLC5A2, SLC8A3, SLC12A1, SLC12A2, SLC13A1, SLC34A1, SLC20A1, SP100, SRP9, SRP14, STYX, TAF7, SERPINA7, ICAM5, TPT1, HSP90B1, TRPC3, TRPC5, TSC1, TULP1, UBB, UBE2L3, UBE3A, SUMO1, UPK3A, UVRAG, VAV1, VDAC2, VIL1, WFS1, YWHAZ, ZBTB17, SLC30A2, TUBA1A, FZD5, KCNAB1, TUSC3, SLC25A16, AAAS, SLC14A2, CLTCL1, BAP1, UXT, EEA1, CUL3, OGT, PIK3R3, AP3B1, BLZF1, RUVBL1, USO1, SSNA1, DYNLL1, PEA15, SRSF9, RIPK1, PROZ, EIF2S2, AP1M1, AP3D1, CDKL2, RPL14, CLDN10, UNC119, RGN, SEC22C, RASSF9, ZW10, KCNAB3, VAPB, ITGB1BP1, COPB2, TRIP11, KIF3B, SLC22A8, COG1, KCNK6, GSTO1, AKAP7, SLC4A7, GOSR1, BAG4, SEC22B, VPS26A, GOSR2, AKAP12, CLINT1, IFT140, ZFYVE16, ATG13, PIEZO1, SNX17, DNAJC6, C2CD5, ZC3H11A, OSBPL2, SMG7, SGSM2, FAM20B, RBM8A, OXSR1, GOLGA5, SLC12A6, HDAC6, BCL2L11, HCN4, TOM1, AP1M2, SAE1, ABCC5, ABCB6, ABCC9, ATP9A, COL4A3BP, ARPC5, ARPC1B, ACTR2, ARPC2, SGK2, ARFRP1, AKAP9, WASF2, SLC35B1, KCNMB2, STAM2 |
1565 | GO:0009059 | 0.00 | 1.38 | 652.28 | 766 | 2760 | macromolecule biosynthetic process | ABCA1, ABCA2, ABL1, ABO, ACTL6A, ACTN1, ACVR2B, ACVRL1, AEBP1, AGTR2, NR0B1, ALAS2, ALK, ALX3, ANG, ANGPT1, ANXA3, XIAP, BIRC5, APP, ARCN1, ARG1, PHOX2A, ARNT, ARNTL, ART1, ASCL1, ASCL2, ATF4, RERE, ATR, ATRX, BACH1, BCL3, PRDM1, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTK, CAMK2A, CANX, CAT, RUNX2, CBL, CCNC, CCNE1, CCNT2, CD3D, CD3E, CD4, CD28, CD86, TNFRSF8, TNFSF8, CD36, CD59, CDK11B, CDC25A, CDC25C, CDH1, CDK2, CDK4, CDK8, CDKN1A, CDX2, CEBPE, CENPB, CENPF, CHD2, CHD4, CHEK1, CHUK, CIRBP, CLU, COL1A1, COPA, COX6A1, COX6B1, COX7C, COX8A, CREB1, CRX, CRY2, CSNK1D, CSNK2A1, CSNK2A2, VCAN, CSPG4, CSTF3, CTGF, CTH, CTNND2, DAD1, DAPK3, DAZ1, DCN, DDX1, DDX5, DDX6, DHFR, DKC1, DLX5, DYNC1H1, DNM2, DNMT1, DNMT3B, DNTT, DRD3, ARID3A, RCAN1, TSC22D3, DUSP1, E2F6, E4F1, EBF1, TYMP, ECM1, EDA, S1PR1, EEF1B2, EFNA1, EGR2, EGR3, EGR4, EIF1AX, EIF2B1, EIF4A1, EIF4E, EIF4G2, EIF5, EIF5A, ELAVL2, ELAVL1, ELK1, EMX1, EMX2, EN1, EP300, EPHA5, EPRS, EYA4, ERCC3, ERCC6, ERF, ERG, ESRRG, ETS1, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EXT2, EXTL1, EXTL3, EYA2, EZH1, F2, F2R, PTK2B, FAU, FBN1, EFEMP1, FCER2, FEN1, GPC4, FGF4, FGF7, FGFR3, FSHB, NR5A2, FUT6, FUT8, FZD2, GALR1, GAPDH, GATA4, GATA6, GCG, KAT2A, GDF9, B4GALT1, GHSR, GPC3, GMDS, GOLGA2, GOLGB1, GPX2, GRB7, GRIA1, GSC2, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, GYS2, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, HARS, HBE1, HCLS1, HDGF, HEXA, HEXB, HGF, NRG1, HHEX, HIC1, HIP1, HIVEP2, HLF, HMGN1, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HNRNPC, HOXC10, HOXC11, HOXD8, HOXD9, HOXD10, HOXD12, HSF4, HSPB1, ICAM1, IFI16, SP110, IFNA2, IFNG, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL10, IL12B, ILK, ING2, INHA, INS, INSIG1, EIF3E, IRAK1, IRAK2, IRF1, IRF5, ISL1, ITGAV, JARID2, JUN, JUND, KCNK2, KDR, KIT, LCAT, LIPC, LMO1, LTF, CAPRIN1, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MEOX2, MGAT2, MGAT3, KITLG, CIITA, ATXN3, AFF1, FOXO4, PPP1R12A, DRG1, TONSL, CNOT2, YBX1, NTRK3, NUP98, NVL, OMD, ORC1, ORC2, ORC4, OTX1, OTX2, OVOL1, PA2G4, PRDX1, SERPINE1, PAM, PAX3, PAX9, PCK1, PCNA, CHMP1A, PDE8A, CFP, PGR, PHF2, PHKG1, PIM1, PPID, PPM1B, PPP1R8, PPP2R1A, PPP5C, PPP6C, PRG2, PRIM2, PRKAA1, PRKAG1, PRKAR1A, PRKCI, PRKD1, PRKCQ, PRKCSH, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PTAFR, PTEN, PTGIS, PTMA, PTMS, PURA, RAB1A, RAC1, RAD21, RAD51, RAF1, RAN, RANBP2, RARA, RARB, RB1, RBBP6, RBL2, RBM4, RBMS1, UPF1, DPF2, REST, REV3L, RFC3, RFC4, RFC5, RFX1, RFX3, RFXAP, RGS12, RHEB, RLF, RNF6, RPA2, RPA3, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL36AL, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS6KA1, RPS6KB1, RPS6KB2, RPS11, RPS19, RPS20, RPS27, RRM1, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A11, S100A12, SALL1, SATB1, CCL21, XCL1, SDC4, TRAPPC2, SET, SETMAR, SFPQ, SFRP5, SRSF1, SRSF5, SRSF7, SFSWAP, SFTPD, SGK1, SHC1, SIM2, SIX3, SLC2A4, SLC9A1, SMARCA1, SMARCA2, SMARCA4, SMARCD3, SMARCE1, SNAI1, SNAPC3, SNCA, SNRPE, SNRPF, SOD2, SOX3, SOX9, SOX10, SOX11, SP1, SP100, UAP1, SPIB, SREBF1, SRF, SRP9, SRP14, SRY, TRIM21, SSRP1, STAT2, STAT3, STAT4, STAT5B, STAT6, TAF4B, TAF7, TAF10, TAL1, TBL1X, TBP, HNF1A, ZNF354A, NR2F1, NR2F2, KLF10, TMPO, TNFRSF1A, TNNI2, TOP1, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TSC1, TSG101, TTF1, TUFM, TULP3, TNFSF4, TYMS, UBB, UBA7, UBE2D2, UBE2L3, UBE3A, SUMO1, UCP1, SCGB1A1, NR1H2, USF1, VAV1, VEGFB, EIF4H, WFS1, WNT1, WNT11, XRCC5, YY1, YWHAZ, ZFP37, ZFPL1, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF91, ZNF99, ZNF124, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZXDA, PRDM2, FZD5, AIMP2, ARHGEF5, TUSC3, NUP214, SLC25A16, FOSL1, FGF23, AAAS, CDK2AP1, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, SMC1A, USP9Y, HIST1H4I, PICALM, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NSMAF, DYRK2, CUL4A, CUL3, CUL2, KLF11, SMARCA5, OGT, IKBKG, IKBKAP, HAT1, GAS7, PIR, BLZF1, KHSRP, STK16, RGS20, SLC25A12, RUVBL1, KLF7, USO1, TP63, EIF4EBP3, CHRD, DDX3Y, DYNLL1, EIF3G, EIF4G3, SRSF9, GALNT4, B4GALT4, B4GALT3, B3GALT2, SERPINB7, TRADD, EED, RIPK1, RIPK2, DPM2, SAP30, HESX1, PER3, TAX1BP1, EIF2B3, EIF2B2, EIF2S2, BUD31, PHOX2B, HIST1H3F, HIST1H2AG, RPS6KA4, TNFSF18, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, RPL14, USP2, RGN, PDLIM1, SMC3, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, DDX21, AURKB, CCPG1, ITGB1BP1, COPB2, ZNF235, KLF4, COPS2, TRIP11, HMGN3, GTF3C5, GTF3C4, GTF3C3, B4GALT6, RPL23, COG1, RECQL5, ZRANB2, HAND1, ZNF264, EIF2AK3, FHL5, CHST3, ATG5, ONECUT2, PIGL, ADAMTS3, LITAF, TBPL1, GOSR1, TMEM59, ZNF254, SEC22B, GTPBP1, GOSR2, CLOCK, SOX13, RBM39, RNF14, NUP155, HS2ST1, ZNF516, EIF5B, SDC3, KDM4A, VGLL4, NUP93, BZW1, ST18, ZNF646, SETD1A, ZFYVE16, EIF4A3, RB1CC1, ARHGEF11, GINS1, ZEB2, ZBTB24, ZNF518A, EPM2AIP1, RNF10, ZBTB5, RBM8A, HS3ST3B1, HS3ST1, NR1I3, NR1H4, NR1D2, RBX1, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, GNE, PIGK, ABCC5, RAD50, ZNF263, TRAP1, CHST4, SLC25A13, SLC25A15, ZNF256, RNF41, EIF1, OLIG2, PRG4, DENND4A, IRX5, RAMP3 |
1566 | GO:0034641 | 0.01 | 1.37 | 76.60 | 96 | 359 | cellular nitrogen compound metabolic process | ACADM, ALAD, ALAS2, AUH, BCKDHA, BGLAP, BLVRA, CDK4, CDO1, CIRBP, TPP1, CLN5, CPOX, CRAT, CTSH, CYP3A4, DAZ1, DBH, DBT, ACE, SARDH, DPEP1, EEF1B2, EIF1AX, EIF2B1, EIF4G2, EIF5, EIF5A, ELAVL1, F2, F7, F10, G6PC, GALC, GGT7, GLDC, GLUD1, GM2A, GOT2, GPT, GRB7, GRIN2A, GSTZ1, HLCS, HMBS, HNMT, HSPB1, IVD, LTA4H, CAPRIN1, OAT, P2RX1, P2RX4, PAH, PCSK5, PROC, PSPH, PYCR1, QDPR, RPL36AL, RPS6KB1, RPS6KB2, SHMT2, SLC34A1, SLC22A5, SRD5A1, SRP9, SRP14, SUOX, TAT, TUFM, TYR, UROS, TRPV1, EIF4H, SLC25A16, NSMAF, SLC25A12, EIF4EBP3, ALDH4A1, EIF3G, EIF4G3, PROZ, VNN2, SLC5A6, EIF2B3, EIF2B2, EIF2S2, PCSK7, GSTO1, EIF5B, ABCB6, COL4A3BP, TRAP1, ATP6AP2, EIF1 |
1567 | GO:0006820 | 0.01 | 1.37 | 83.19 | 104 | 352 | anion transport | ABAT, ABCA1, ABCA2, ABCA4, ACACB, AGTR2, ALB, ABCD1, ANXA1, AQP6, ARG1, ATP1A2, TSPO, CA4, CACNA1A, CACNB4, CD36, AKR1C4, CHRNB2, CLCA1, CLCN3, CLCN6, CLCN7, CLCNKA, CLCNKB, CLNS1A, CNR1, CPT1B, CPT2, CRH, CRY2, CTNS, ACE, DRD3, GABRA4, GABRA5, GABRE, GABRG1, GABRR1, GABRR2, GLRA1, GOT2, HBA2, KCNJ10, KCNN4, NTRK2, NTSR1, P2RX4, P2RX7, P2RY2, P2RY4, P2RY6, PCP4, FXYD3, PTAFR, ABCD3, RAB3B, RHAG, RXRA, SLC1A6, SLC4A1, SLC6A6, SLC6A7, SLC6A13, SLC7A1, SLC7A4, SLC10A1, SLC12A1, SLC12A2, SLC13A1, SLC34A1, SLC20A1, SLCO2A1, SLCO1A2, SLC22A5, SNAP25, SNCA, STC1, SYT1, TRPC4, VDAC2, TRPV1, FGF23, SLC7A5, SLC10A3, SLC25A12, VAMP8, RIPK1, SLC5A6, SLC13A2, SLC16A6, SLC16A5, SLC6A5, SLC9A3R1, SLC22A8, SLC4A7, NR1H4, SLC12A6, ABCC5, ATP9A, SLC25A13, SLC25A15, SLC35B1, ABCC4 |
1568 | GO:0022604 | 0.01 | 1.37 | 65.46 | 82 | 277 | regulation of cell morphogenesis | ABL1, ANXA1, ARHGAP4, BBS4, BMPR2, CACNA1A, CHN1, CHRNB2, COL1A1, CSF1R, DAPK3, DCC, DIAPH1, DNM2, LPAR1, EFNA1, EFNA5, CTTN, EPHB3, F2, PTK2B, FBLN1, FGA, FGD1, FGR, FYN, GAS2, GDI1, GOLGA4, HEXB, NRG1, FOXA2, ICAM1, ILK, KDR, KIT, LIMK1, CAPRIN1, SMAD3, SMAD7, NRCAM, NTRK2, NTRK3, PALM, PTEN, PTK2, PTN, RAC1, RAC3, RAP2A, RNF6, S100A13, SALL1, SEMA3F, SGK1, SNAI1, SPARC, SRF, SYT1, SYT4, CNTN2, TNR, TTC3, VIL1, SEMA3B, RND2, GAS7, NRP1, ARHGEF7, ARHGEF1, ZMYM6, ITGB1BP1, SLIT2, SLC9A3R1, ATG5, AATK, RAPGEF2, RIMS2, SEMA3E, IFT140, CUL7, ARPC2 |
1569 | GO:1903506 | 0.00 | 1.37 | 444.07 | 533 | 1879 | regulation of nucleic acid-templated transcription | ABCA2, ABL1, ACTL6A, ACTN1, ACVR2B, ACVRL1, AEBP1, AGTR2, NR0B1, ALK, ALX3, ANXA3, XIAP, BIRC5, APP, PHOX2A, ARNT, ARNTL, ASCL1, ASCL2, ATF4, RERE, ATRX, BACH1, BCL3, PRDM1, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTK, CAMK2A, CAT, RUNX2, CBL, CCNC, CCNE1, CCNT2, CD3D, CD28, CD86, TNFSF8, CD36, CDK11B, CDH1, CDK2, CDK8, CDX2, CEBPE, CENPB, CENPF, CHD2, CHD4, CHEK1, CHUK, CLU, COL1A1, CREB1, CRX, CRY2, CSNK2A1, CSNK2A2, CTH, CTNND2, DAPK3, DCN, DDX1, DDX5, DHFR, DLX5, DNM2, DNMT1, DNMT3B, DRD3, ARID3A, RCAN1, TSC22D3, E2F6, E4F1, EBF1, ECM1, EDA, S1PR1, EFNA1, EGR2, EGR3, EGR4, ELAVL2, ELK1, EMX1, EMX2, EN1, EP300, EPHA5, EYA4, ERCC3, ERCC6, ERF, ERG, ESRRG, ETS1, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA2, EZH1, F2R, FBN1, EFEMP1, FGF4, FGF7, FGFR3, FSHB, NR5A2, FZD2, GALR1, GATA4, GATA6, GCG, KAT2A, GDF9, GPC3, GSC2, GTF2I, GTF3A, BRF1, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, HBE1, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIP1, HIVEP2, HLF, HMGN1, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD8, HOXD9, HOXD10, HOXD12, HSF4, ICAM1, IFI16, SP110, IFNA2, IFNG, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL10, ILK, ING2, INS, INSIG1, IRAK1, IRAK2, IRF1, IRF5, ISL1, JARID2, JUN, JUND, KIT, LMO1, LTF, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MEOX2, CIITA, ATXN3, AFF1, FOXO4, PPP1R12A, TONSL, CNOT2, YBX1, NTRK3, ORC1, ORC2, OTX1, OTX2, OVOL1, PA2G4, SERPINE1, PAM, PAX3, PAX9, PCK1, PCNA, CHMP1A, PDE8A, PGR, PHF2, PIM1, PPID, PPP1R8, PPP2R1A, PRKAA1, PRKAR1A, PRKCI, PRKD1, PRKCQ, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PTAFR, PTEN, PTGIS, PURA, RAD21, RAF1, RAN, RARA, RARB, RB1, RBL2, DPF2, REST, RFX1, RFX3, RFXAP, RLF, RNF6, RPS3, RPS6KA1, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A12, SALL1, SATB1, XCL1, TRAPPC2, SET, SFPQ, SFRP5, SFSWAP, SGK1, SIM2, SIX3, SLC9A1, SMARCA1, SMARCA2, SMARCA4, SMARCD3, SMARCE1, SNAI1, SNAPC3, SNCA, SOD2, SOX3, SOX9, SOX10, SOX11, SP1, SP100, SPIB, SREBF1, SRF, SRY, TRIM21, SSRP1, STAT2, STAT3, STAT4, STAT5B, STAT6, TAF4B, TAF7, TAF10, TAL1, TBL1X, TBP, HNF1A, ZNF354A, NR2F1, NR2F2, KLF10, TMPO, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TSG101, TTF1, TULP3, TNFSF4, TYMS, UBB, UBE2D2, UBE2L3, UBE3A, SUMO1, UCP1, SCGB1A1, NR1H2, USF1, VAV1, WFS1, WNT1, WNT11, XRCC5, YY1, ZFP37, ZFPL1, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF91, ZNF99, ZNF124, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZXDA, PRDM2, FZD5, ARHGEF5, FOSL1, FGF23, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, USP9Y, HIST1H4I, PICALM, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, CUL3, CUL2, KLF11, SMARCA5, OGT, IKBKG, IKBKAP, HAT1, GAS7, PIR, BLZF1, KHSRP, STK16, RGS20, RUVBL1, KLF7, TP63, CHRD, DYNLL1, TRADD, EED, RIPK1, RIPK2, SAP30, HESX1, PER3, TAX1BP1, BUD31, PHOX2B, HIST1H3F, HIST1H2AG, RPS6KA4, TNFSF18, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, USP2, PDLIM1, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, AURKB, CCPG1, ITGB1BP1, ZNF235, KLF4, COPS2, TRIP11, HMGN3, RECQL5, ZRANB2, HAND1, ZNF264, EIF2AK3, FHL5, ONECUT2, LITAF, TBPL1, ZNF254, CLOCK, SOX13, RBM39, RNF14, ZNF516, KDM4A, VGLL4, BZW1, ST18, ZNF646, SETD1A, ZFYVE16, RB1CC1, ARHGEF11, ZEB2, ZBTB24, ZNF518A, RNF10, ZBTB5, NR1I3, NR1H4, NR1D2, RBX1, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, ZNF263, ZNF256, RNF41, OLIG2, DENND4A, IRX5, RAMP3 |
1570 | GO:0070727 | 0.00 | 1.37 | 215.30 | 265 | 911 | cellular macromolecule localization | ABL2, ACTL6A, ADAR, AGTR2, ANGPT1, ARCN1, ARL1, ARL2, ARNTL, RERE, ATR, ATRX, BAD, BARD1, BAX, BBS4, BCL2L1, BCL3, BICD1, BMP4, BMPR1A, BNIP3L, BRCA2, BSG, BUB1B, TSPO, CACNA1A, CAV3, CBLB, CCNB1, CD4, CD36, SCARB2, CD63, CDH1, CDKN1A, CENPA, CHRM1, AP1S1, AP2S1, COL1A1, COPA, CSE1L, CSNK1D, CSNK2A2, CTNNA1, CTSK, DDX1, DIAPH1, DKC1, DLG2, DLG3, DPP6, EDA, EGR2, EPHA2, EIF5A, EMP2, CTTN, ETV5, F2R, FAU, FGF7, FLOT2, FYB, FYN, KAT2A, GDI1, GFER, GNAQ, GOLGA4, GPR26, GRID2, HIST1H1B, HCLS1, NRG1, HHEX, HNMT, HSPA4, HSPA9, IFIT1, IFNG, IGF1, IL10, IL12B, IL18, INS, ITGA4, ITGB1, JUN, KCNA1, KPNA1, KPNA2, KPNA3, KPNA4, IPO5, LTBP2, SMAD3, SMAD7, NUBP1, TONSL, YBX1, NUP98, OAZ1, OAZ2, PRDX1, PALM, PCM1, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PPM1B, PRKCI, PRKCQ, PTN, PEX19, PEX5, RAB6A, RAB27A, RAC1, RAC2, RAD21, RAN, RANBP2, RANGAP1, RAP2A, RB1, RNASE2, RPGR, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, CLIP1, RTN2, RYR2, SFRP5, STIL, SIX3, SLC9A1, SLC12A1, SUMO3, SOX9, SP100, SPAG4, SREBF1, SRP9, SRP14, STAT3, STAU1, STYX, CNTN2, DYNLT1, TNFRSF1A, HSP90B1, TRIP6, TULP1, TULP2, TULP3, UBE2L3, SUMO1, USP4, VIL1, WNT11, WRB, YWHAZ, ZIC1, ZBTB17, FZD5, NUP214, AKAP1, MADCAM1, CLTCL1, BAP1, FZD7, DYRK2, OGT, CNTNAP1, AP3B1, BLZF1, PRPF18, RGS20, RUVBL1, USO1, SSNA1, AKR1C3, NUMB, DYNLL1, VAMP8, STX11, TNFSF14, LIN7A, NRP1, AP1M1, HERC2, AP3D1, CDKL2, RPL14, LATS1, ARHGEF2, RASSF9, ZW10, AURKB, ITGB1BP1, COPB2, TRIP11, RPL23, SLC9A3R1, ZFYVE9, NRXN1, NRXN2, PEX16, EIF2AK3, PICK1, AKAP6, LITAF, TMEM59, BAG4, AKAP12, NUP155, IPO13, NUP93, RAPGEF2, CROCC, RIMS2, IFT140, ZFYVE16, ATG13, SNX17, TOMM20, C2CD5, KLHL21, FAM20B, HDAC6, PDCD6, BCL2L11, PIGK, TOM1, AP1M2, SAE1, ARFRP1, NUTF2, STAM2, RAMP3 |
1571 | GO:0051252 | 0.00 | 1.37 | 460.61 | 551 | 1949 | regulation of RNA metabolic process | ABCA2, ABL1, ACTL6A, ACTN1, ACVR2B, ACVRL1, AEBP1, AGTR2, NR0B1, ALK, ALX3, ANXA3, XIAP, BIRC5, APP, PHOX2A, ARNT, ARNTL, ASCL1, ASCL2, ATF4, RERE, ATRX, BACH1, BARD1, BCL3, PRDM1, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTK, CAMK2A, CAT, RUNX2, CBL, CCNB1, CCNC, CCNE1, CCNT2, CD3D, CD28, CD86, TNFSF8, CD36, CDK11B, CDH1, CDK2, CDK8, CDX2, CEBPE, CENPB, CENPF, CHD2, CHD4, CHEK1, CHUK, CLU, CLK1, CLK3, COL1A1, CREB1, CRX, CRY2, CSNK2A1, CSNK2A2, CTH, CTNND2, DAPK3, DCN, DDX1, DDX5, DHFR, DLX5, DNM2, DNMT1, DNMT3B, DRD3, ARID3A, RCAN1, TSC22D3, E2F6, E4F1, EBF1, ECM1, EDA, S1PR1, EFNA1, EGR2, EGR3, EGR4, ELAVL2, ELK1, EMX1, EMX2, EN1, EP300, EPHA5, EYA4, ERCC3, ERCC6, ERF, ERG, ESRRG, ETS1, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA2, EZH1, F2R, FBN1, EFEMP1, FGF4, FGF7, FGFR3, AFF2, FSHB, NR5A2, FZD2, GALR1, GATA4, GATA6, GCG, KAT2A, GDF9, GPC3, GSC2, GTF2I, GTF3A, BRF1, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, HBE1, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIP1, HIVEP2, HLF, HMGN1, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD8, HOXD9, HOXD10, HOXD12, HSF4, ICAM1, IFI16, SP110, IFNA2, IFNG, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL10, ILK, ING2, INS, INSIG1, IRAK1, IRAK2, IRF1, IRF5, ISL1, JARID2, JUN, JUND, KIT, LMO1, LTF, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MEOX2, CIITA, ATXN3, AFF1, FOXO4, PPP1R12A, TONSL, CNOT2, YBX1, NTRK3, OAS3, ORC1, ORC2, OTX1, OTX2, OVOL1, PA2G4, SERPINE1, PAM, PAX3, PAX9, PCK1, PCNA, CHMP1A, PDE8A, PGR, PHF2, PIM1, PPID, PPP1R8, PPP2R1A, PRKAA1, PRKAR1A, PRKCI, PRKD1, PRKCQ, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PTAFR, PTEN, PTGIS, PURA, RAD21, RAF1, RAN, RARA, RARB, RB1, RBL2, RBM4, UPF1, DPF2, REST, RFX1, RFX3, RFXAP, RLF, RNF6, RPS3, RPS6KA1, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A12, SALL1, SATB1, XCL1, TRAPPC2, SET, SFPQ, SFRP5, SRSF7, SFSWAP, SGK1, SIM2, SIX3, SLC9A1, SMARCA1, SMARCA2, SMARCA4, SMARCD3, SMARCE1, SNAI1, SNAPC3, SNCA, SNRNP70, SOD2, SOX3, SOX9, SOX10, SOX11, SP1, SP100, SPIB, SREBF1, SRF, SRPK2, SRY, TRIM21, SSRP1, STAT2, STAT3, STAT4, STAT5B, STAT6, SUPV3L1, TAF4B, TAF7, TAF10, TAL1, TBL1X, TBP, HNF1A, ZNF354A, NR2F1, NR2F2, KLF10, TMPO, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TSG101, TTF1, TULP3, TNFSF4, TYMS, UBB, UBE2D2, UBE2L3, UBE3A, SUMO1, UCP1, SCGB1A1, NR1H2, USF1, VAV1, WFS1, WNT1, WNT11, XRCC5, YY1, ZFP37, ZFPL1, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF91, ZNF99, ZNF124, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZXDA, PRDM2, FZD5, ARHGEF5, FOSL1, FGF23, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, USP9Y, HIST1H4I, PICALM, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, CUL3, CUL2, KLF11, SMARCA5, OGT, IKBKG, IKBKAP, HAT1, GAS7, PIR, BLZF1, KHSRP, STK16, RGS20, RUVBL1, KLF7, TP63, CHRD, DYNLL1, SRSF9, TRADD, EED, RIPK1, RIPK2, SAP30, HESX1, PER3, TAX1BP1, BUD31, PHOX2B, HIST1H3F, HIST1H2AG, RPS6KA4, TNFSF18, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, USP2, RGN, PDLIM1, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, AURKB, CCPG1, ITGB1BP1, ZNF235, KLF4, COPS2, TRIP11, HMGN3, RECQL5, ZRANB2, HAND1, ZNF264, EIF2AK3, FHL5, ONECUT2, LITAF, TBPL1, ZNF254, GTPBP1, CLOCK, SOX13, RBM39, RNF14, ZNF516, KDM4A, VGLL4, BZW1, DHX34, ST18, ZNF646, SETD1A, ZFYVE16, RNF40, RB1CC1, ARHGEF11, ZEB2, ZBTB24, ZNF518A, RNF10, ZBTB5, RBM8A, NR1I3, NR1H4, NR1D2, RBX1, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, ZNF263, ZNF256, RNF41, OLIG2, DENND4A, IRX5, RAMP3 |
1572 | GO:0006470 | 0.04 | 1.37 | 43.96 | 55 | 186 | protein dephosphorylation | ACP1, AGTR2, CALM3, CDC25A, CDC25C, CRY2, DLG2, DLG3, DUSP1, DUSP5, EYA4, EYA2, GPLD1, IFNG, ITGA1, SMAD3, PPP1R12A, PPM1B, PPP2CB, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PPP4C, PPP5C, PPP6C, PTEN, PTPN4, PTPN6, PTPN7, PTPRA, PTPRE, PTPRH, PTPRJ, PTPRN, PTPRN2, PTPRR, PTPRS, SBF1, SET, STYX, HSP90B1, TSC1, AKAP1, PPM1D, CDC14B, RGN, CTDP1, AKAP6, BAG4, DLGAP5, DNAJC6, NUAK1, FARP1, CTDSPL |
1573 | GO:1903047 | 0.00 | 1.37 | 89.11 | 111 | 383 | mitotic cell cycle process | ABL1, ANXA1, BIRC5, APP, ATRX, BBS4, BMP4, CAMK2A, CCNF, CCNG2, CD28, CDK11B, CDC25A, CDC25C, CDK3, CDK4, CDK6, CENPA, CHEK1, CKS1B, CSNK1D, DAPK3, DYNC1H1, DNM2, DRD3, E4F1, EIF4E, EML1, EP300, ERCC3, FGFR3, GOLGA2, HGF, IGF1, IGF1R, IGF2, IL1A, INS, ITGB1, KIF25, PPP1R12A, PPP1R12B, NUMA1, NUP98, ORC2, ORC4, PCM1, CHMP1A, PIM1, PPP2R2A, PPP5C, PPP6C, PRIM2, PRKAR2B, PRKCQ, PTPN6, RAD21, RAD51C, RAD51B, RAN, RANBP2, RPA3, RPS3, RPS6KB1, CLIP1, STIL, SMARCA4, SMARCD3, ADAM17, DYNLT3, DYNLT1, TPD52L1, TUBA4A, TUBG1, UBE2E2, VRK1, TUBA1A, NUP214, AAAS, CLTCL1, USP9X, CUL4A, CUL2, PPM1D, RUVBL1, SSNA1, DYNLL1, PHOX2B, RNF8, USP8, LATS1, SMC3, CCNB2, CTDP1, ARHGEF2, AURKB, KIF3B, RECQL5, NUP155, CEP135, NUP93, CKAP5, CUL7, GINS1, KLHL21, DCLRE1A, SMC4, KIF20A, AKAP9, CTDSPL, SPRY1 |
1574 | GO:0022411 | 0.01 | 1.36 | 77.84 | 97 | 332 | cellular component disassembly | ACTL6A, ADD1, ANXA5, APAF1, BAX, BNIP3L, TSPO, CAPG, CCNB1, COX8A, CSNK2A2, DFFA, DNASE1L3, EIF5A, CTTN, FANCF, FAU, GABRA5, GAS2, KAT2A, GOLGA2, NRG1, HMGA1, KCNK3, KPNA1, NTHL1, NUP98, P2RX5, CHMP1A, PEX13, PRKCQ, PTK2, RANBP2, UPF1, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, SATB1, SET, SGK1, SLCO1A2, SLC22A3, SMARCA4, SMARCD3, SMARCE1, SNRPD1, SNRPF, SREBF1, STAT2, TOP2A, NR2C2, UBB, VIL1, VIM, VRK1, ZBTB17, ZNF189, FZD5, NUP214, AAAS, CHAF1B, RUVBL1, SYNJ1, RPL14, CCNB2, ARHGEF2, AURKB, RPL23, CHST3, ATG5, NUP155, NUP93, ATG13, PHYHIP, TOMM20, DNAJC6, FGFBP1, HDAC6 |
1575 | GO:0051056 | 0.05 | 1.36 | 39.23 | 49 | 166 | regulation of small GTPase mediated signal transduction | ABCA1, ABL2, ARHGAP4, ARHGAP6, ARHGDIB, BCR, CHN1, CHN2, DNM2, LPAR1, F2R, FGD1, GDI1, GDI2, RAPGEF1, NRG1, IGF1, ITGB1, KITLG, PPP2CB, RAC1, RAC2, RAC3, RAF1, RAP1GAP, RASA2, SIPA1, SOS2, VAV1, ARHGEF5, SHOC2, CUL3, OGT, ARHGEF7, ARHGEF1, DGKI, ARHGEF2, GPR55, TRIP10, SLIT2, ARHGAP29, RALGPS1, ARHGAP32, ARHGEF11, RHOBTB1, ARHGAP25, RASA4, FARP1, SPRY1 |
1576 | GO:0048468 | 0.04 | 1.36 | 43.92 | 55 | 198 | cell development | ANG, ANGPT2, BCL2L1, BGLAP, BMP1, BMP3, BMP8B, BRCA2, BTK, CASP5, CASQ1, CASQ2, RUNX2, CD9, COL11A1, DIAPH2, DNASE1L3, EDNRA, EIF2B1, FANCG, GATA6, GHRHR, HEXB, HSF4, IL1A, ING2, INHA, JUND, KCNJ10, KDR, PAX3, PIP4K2A, PPP2R1B, PRKAR1A, RHAG, RPS6KB1, RYR1, S100A8, S100A9, CCL21, SMARCA2, SMARCA4, TAF4B, FZD5, EIF2B3, EIF2B2, RNF8, EIF2AK3, GDF15, TBPL1, SPAG6, ZEB2, REC8, BCL2L11, WASF2 |
1577 | GO:0061024 | 0.00 | 1.36 | 156.69 | 193 | 663 | membrane organization | ABCA1, ABCA4, ACTB, ANXA1, APP, ARCN1, ARF1, BAD, BAX, BCL2A1, BCL2L1, BNIP3L, BSG, CACNA1A, CALM3, CAMK2A, CAV3, CCNB1, CD9, CD36, CD59, CDH1, AP1S1, AP2S1, CLCN3, CLU, CNP, COPA, CSNK1D, DLG2, DLG3, DYNC1H1, DNM2, DPP6, EPHA2, EMP2, EPS15, ETV5, EYA2, FAU, FLOT2, FTL, FYB, GDI1, GJB1, GOLGA2, GOLGA4, GOLGB1, GRIA1, HIP1, HSPA4, IFNG, INS, INSIG1, ITGA4, ITGB1, KCNN4, MAL, NRCAM, NUP98, OPA1, P2RX7, PALM, SERPINA5, CHMP1A, PPP2R1A, PPP2R2A, PPP6C, PRKAG1, PRKCI, PTEN, PTN, PEX19, PEX5, RAB1A, RAB4A, RABIF, RAC1, RALA, RANBP2, RAP2A, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, CLIP1, S100A9, TRAPPC2, SLC2A4, SLC9A1, SLC12A1, SNAP25, SNCA, SPAG4, SPAM1, SRP9, SRP14, STAT3, STXBP3, SYP, SYT1, SYT4, CNTN2, TAZ, TNFRSF1A, TSG101, TULP1, TULP2, TULP3, UBB, SUMO1, UPK2, UVRAG, VIL1, VRK1, WRB, YWHAZ, NUP214, AAAS, MADCAM1, DYSF, PICALM, EEA1, CUL3, TPST2, OGT, BLZF1, USO1, SSNA1, NUMB, DYNLL1, VAMP8, STX11, LIN7A, SYNJ1, AP1M1, AP3D1, RPL14, SYT7, SEC22C, CCNB2, RABEP1, VAPB, ITGB1BP1, COPB2, SNAP29, RPL23, SLC9A3R1, KIF3B, NRXN1, NRXN2, COG1, PEX16, PICK1, GOSR1, TMEM59, BAG4, SEC22B, GOSR2, NUP155, CLINT1, NUP93, RAPGEF2, TOMM20, DNAJC6, C2CD5, SNAP91, PDCD6IP, BCL2L11, AP1M2, ATP9A, ARFRP1, STAM2, RAMP3, ZMPSTE24 |
1578 | GO:0009966 | 0.02 | 1.36 | 56.86 | 71 | 258 | regulation of signal transduction | ABCA1, BIRC5, APLP2, APP, ARHGDIB, BCL3, BCR, CNGA1, CRH, RCAN1, EP300, EPHB1, FGD1, GAS1, GDI1, GDI2, GNAI1, GNAT1, GNGT1, GUCA1A, GUCY2F, GUCY2D, HRC, IFNA5, IFNA13, IFNA17, IFNA21, IFNGR1, IFNW1, IRF1, KCNJ1, LLGL2, OTX2, PRDX1, PLN, PRCP, RAC2, RAC3, RAP1GAP, RAP2A, RCVRN, RNF6, SIPA1, STAT2, STYX, SYP, DYNLT1, TSG101, SUMO1, VAV1, ZIC1, OGT, INPP4B, TAX1BP1, BAZ1B, RGN, ARHGEF1, TRIP10, ARHGAP29, RNF14, GUCA1C, RALGPS1, IFT140, ARHGAP32, ARHGEF11, RHOBTB1, ARHGAP25, FARP1, RNF41, RCAN2, RAMP3 |
1579 | GO:0006790 | 0.03 | 1.35 | 49.08 | 61 | 208 | sulfur compound metabolic process | ACACB, ACPP, AHCY, ANGPT1, CACNA1A, CDO1, CPS1, VCAN, CSPG4, CTH, CTNS, DCN, DNMT1, DNMT3B, DPEP1, ESD, EXT2, EXTL1, EXTL3, GPC4, GALNS, B4GALT1, GGT7, GPC3, GPX1, GSTZ1, HEXA, HEXB, HLCS, IDH1, IDS, IDUA, IGF1, LIPC, OMD, OGDH, SDC4, SMS, STAT5B, SULT1E1, SULT1A3, SULT1C2, SULT2B1, SUOX, TPST2, TPST1, DGAT1, B4GALT4, B4GALT3, SUCLG1, VNN2, SLC5A6, KYNU, PAPSS1, B4GALT6, GSTO1, CHST3, SDC3, SPOCK2, HS3ST3B1, CHST4 |
1580 | GO:0044265 | 0.03 | 1.35 | 47.49 | 59 | 203 | cellular macromolecule catabolic process | BNIP3L, ZFP36L2, CTSH, CTSK, DDX6, EIF4A1, EIF4E, FAP, FAU, FEN1, GPX1, EIF3E, CNOT2, CNOT4, PPP1R8, PPP2R1A, PPP2R2A, UPF1, RNASE2, RNASE6, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, SUPV3L1, CLPP, PRPF18, KHSRP, RNASET2, CTSF, RIPK1, RPL14, SOCS6, RPL23, GTPBP1, DHX34, EIF4A3, SMG7, RBM8A, PDCD6IP, RNF41 |
1581 | GO:0071704 | 0.00 | 1.35 | 278.17 | 327 | 1375 | organic substance metabolic process | ABCA3, ABCA4, ABL2, ACO2, ACP1, ACTB, ACTG2, ADAM10, ADD1, ALDH1A3, BIRC3, KLK3, TRIM23, ARF1, ARR3, ATP6AP1, AXL, BBS4, OPN1SW, BCR, BLK, BOK, BSG, BST2, C3, CAPN5, C7, CAPN6, CASP5, CASP9, CD3E, CD4, CD9, TNFRSF8, CD63, CDK3, CDK6, CENPE, CHAD, CHRM1, CHRM3, TBCB, CKS1B, CLCA1, COL4A3, COL4A5, COL4A6, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, COL15A1, CPA1, CR2, CRKL, CRP, CRYBA1, CSF1R, CSF2RB, CSNK1G3, CST6, CTF1, DMBT1, DNM1, DPP4, DPP6, DUSP5, PHC2, EFNA5, EPHA2, SERPINB1, EMP2, EPHA8, EPHB1, EPHB2, EPHB3, EVPL, F3, FBLN1, FCER2, FCN2, FGA, FGF3, FGR, FKBP3, FKBP5, FLOT2, FLT1, FLT3, FLT3LG, FLT4, FPR1, FYB, GAS1, OPN1MW, GFAP, GFER, GLE1, GNAQ, GNG3, GP1BA, GP9, GRB2, RAPGEF1, GRM1, GZMH, CFHR1, HP, HRC, HRG, HSPA9, IAPP, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGFBP6, IL1RAP, IL1RN, IL2RA, IL12B, IL12RB2, IL13, IL18, INHA, INSRR, ITGA1, ITGA5, ITGAV, ITGB1, KCNH2, KDR, KISS1, KLK1, KLKB1, KNG1, LIMK1, MARK3, MAP3K11, OLR1, OXTR, SERPINA5, PCOLCE, PCP4, SERPINF1, PEX12, PFDN2, PFN2, SERPINA4, SERPINB5, SERPINB9, SERPINB13, SERPINI2, PIK3C2B, PI4KA, PIP4K2A, PPIB, PPM1B, PPP2R1B, PRCP, PREP, PRG2, PRKAR1B, PRKAR2A, PRKAR2B, PRKX, PSKH1, PTPN4, PTPN6, PTPN7, PTPRA, PTPRE, PTPRH, PTPRJ, PTPRN, PTPRN2, PTPRR, PTPRS, PZP, RAB3B, RAB5A, RAB6A, RAB27A, RABGGTA, RABGGTB, RAC2, RANGAP1, RAP2A, RAP2B, RASA2, RBP1, RBP2, OPN1LW, RGR, RYK, SORT1, S100A7, ACSM3, SBF1, SERPINB4, CCL22, CCL25, CX3CL1, SDHA, SDHB, SDHD, SELE, SFTPD, STIL, SLC12A1, SLPI, SPINK1, SPOCK1, SPRR2A, SPRR2D, SPRR2E, SPRR2G, SPRR3, ST14, STK10, STYX, XCL2, ADAM17, CNTN2, TBCD, TBCE, SERPINA7, CLEC3B, TPD52L1, TPSAB1, TUBA4A, TYRO3, UBE2E2, KDM6A, UTY, VBP1, VIL1, VIM, TRPV1, VRK1, VTN, TUBA1A, SCG2, AKAP1, BCAR3, TPST2, TPST1, PPM1D, PIK3R3, AGPS, PEA15, DGAT1, SERPINB7, ADAM19, CRADD, TNFSF14, TNFSF10, ADAM15, RIOK3, TNFRSF18, DLK1, TNFRSF10B, TNFRSF10A, DYRK4, PEX11A, CDKL1, INPP4B, NRP1, CDKL2, SOCS3, UNC119, LATS1, ATP6V0D1, STK17B, STK17A, GPR55, SLIT2, SLC9A3R1, ZFYVE9, TMPRSS11D, ADAMTS4, ADAMTS3, ADAMTS2, GDF15, BAG4, NRG2, APBA3, MINPP1, CDC42BPB, PREPL, TRAF4, KLK4, AATK, TTLL4, RIMS2, ADAMTSL2, SLK, ATG13, TOMM20, SCRN1, KIAA0141, DNAJC6, ZC3H11A, NUAK1, JOSD1, OXSR1, TNFSF15, PDCD6, BCL2L11, SH2D3C, SH2D3A, RANBP9, UBA2, SAE1, DPP3, SGK2, FEM1B, AKAP9, ABI2, RASA4, FARP1, PRG4, CTDSPL, SPRY1 |
1582 | GO:0001933 | 0.03 | 1.35 | 49.16 | 61 | 208 | negative regulation of protein phosphorylation | ABL1, ADAR, ANGPT1, BAX, BMP4, CALM3, CAV3, CCNB1, CDKN1A, CHAD, CRYBA1, DCN, DUSP1, DUSP5, FBLN1, GNAQ, GP1BA, RAPGEF1, HHEX, HMGCR, HSPB1, IGF1, IGF1R, IGFBP3, ILK, JUN, SMAD3, SMAD6, SMAD7, NTRK3, P2RX7, PCP4, PPP2R1A, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PTEN, PTPN6, PTPRJ, PTPRR, RB1, SNCA, SPINK1, TAF7, NR2F2, TP73, CUL3, OGT, SOCS3, RGN, LATS1, ITGB1BP1, SOCS6, KLF4, SLIT2, SLC9A3R1, RANBP9, CTDSPL, SPRY1 |
1583 | GO:0019538 | 0.03 | 1.35 | 52.35 | 65 | 246 | protein metabolic process | ACY1, ALB, CAPN5, CAPN1, CAPN6, CASP5, CD86, TNFRSF8, CEBPE, CLCA1, COL11A1, CPA1, CPS1, CR2, VCAN, CTRB1, DPP4, DPP6, FCN2, GPC4, GFAP, GGT7, GHRHR, GP9, HEXA, CFHR1, HP, IDS, IDUA, IL1RAP, IRF1, KLK1, LCAT, LIPC, LTA4H, MGMT, OAZ1, OAZ2, OLR1, CHMP1A, PEPD, PRCP, PREP, PRG2, ST14, STAT5B, TPSAB1, VIP, TP63, ADAM19, ADAM15, ZFYVE9, LIPG, TMPRSS11D, CHST3, ADAMTS4, PREPL, KLK4, SDC3, ADAMTSL2, SCRN1, KIAA0141, JOSD1, HS3ST3B1, DPP3 |
1584 | GO:0043623 | 0.02 | 1.34 | 64.85 | 80 | 275 | cellular protein complex assembly | ABL1, ADD1, ANG, ANGPT1, ARF1, ARHGAP6, ARL2, ATP6V0A1, BBS4, CAPG, CASQ1, CASQ2, CAV3, CD36, CENPA, CENPE, CENPF, AP2S1, CLU, COX15, CSNK1D, CYBA, DIAPH1, DIAPH2, EFNA5, CTTN, EPS15, FGA, GOLGA2, GRB2, HCLS1, NRG1, HIP1, UBE2K, HSPA4, ICAM1, INSIG1, IPO5, NUP98, PFN2, PRKCE, PSMD4, RAB1A, RAC1, RPS3, CLIP1, SCO1, CCL21, SGK1, SNAP25, SNCA, TAZ, TBCD, TRAF2, TUBG1, UVRAG, VBP1, VDAC2, VIL1, ZNF207, PICALM, GAS7, SYNJ1, LATS1, SNAP29, SLIT2, PICK1, BAG4, PDE4DIP, NUP93, TOMM20, SNAP91, HDAC6, RANBP9, ARPC5, ARPC1B, ACTR2, ARPC2, AKAP9, ABI2 |
1585 | GO:0080135 | 0.01 | 1.34 | 73.18 | 90 | 312 | regulation of cellular response to stress | ACTL6A, ATP6V0A1, ATR, BAX, BCL2L1, BNIP3L, TSPO, CAMK2A, CASP9, CAV3, CD44, CHEK1, CLU, CSNK2A2, CTGF, CTSK, DCN, DDX5, CTTN, EP300, EPHB1, ERCC6, PTK2B, FLT4, KAT2A, GRINA, HIC1, HMGCR, IGF1R, IL1A, KCNK2, KDR, MGMT, ATXN3, MAP3K11, NTRK3, NUP98, OPA1, PRDX1, PCNA, PIP4K2A, PPP4C, PTEN, RAD51, RANBP2, RAP2A, RPA2, RPA3, RPS3, CCL21, SETMAR, SNAI1, SREBF1, TNR, TP73, TPD52L1, TPT1, TRAF2, TSC1, DNAJC7, WFS1, ZBTB17, FZD5, ARHGEF5, NUP214, AAAS, FZD4, FZD7, FZD8, CUL4A, OGT, RUVBL1, RIPK1, RIPK2, RNF8, USP14, ARHGEF2, KLF4, RAB33A, EIF2AK3, ATG5, BAG4, BAG3, TRAF4, NUP155, FEZ2, NUP93, ZEB2, BCL2L11, FEM1B |
1586 | GO:0044085 | 0.00 | 1.34 | 291.37 | 350 | 1250 | cellular component biogenesis | ABCA1, ABL1, ABL2, ACACB, ACADS, ACTB, ACTN1, ACVRL1, ADAR, ADD1, ALAD, ANG, ANGPT1, ANXA5, ANXA6, APAF1, BIRC3, BIRC5, APP, ARG1, ARHGAP6, ASL, ATP6V0A1, ATRX, BAD, BICD1, BLK, DST, KLF5, BYSL, CACNA1A, CAPG, CASQ1, CASQ2, CAT, CCNB1, CD3E, CD3G, CD9, ENTPD2, CD59, CD151, CDA, CDH1, CDH6, CDH7, CDH8, CDH9, CDH10, CDH12, CDH15, CDK2, CENPA, CENPE, CENPF, CHD4, CHRNB2, CHRNB4, CIRBP, AP2S1, CLNS1A, COL1A1, COL6A1, COL6A2, COX15, CLDN3, CSNK1D, CTH, CTNNA1, CYBA, DAPK3, ACE, DDX1, DDX6, DIAPH1, DIAPH2, DKC1, DNM1, DYNC1H1, S1PR1, EPHA2, EMP2, EPRS, EPS15, FGA, FGD1, FLOT2, CENPI, GFAP, GHSR, GJA4, GJB1, GLRA1, GOLGA2, GRB7, RAPGEF1, GRIA1, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, HIST1H1A, HBA2, HBE1, HCLS1, NRG1, HIP1, UBE2K, HMGCR, HMGA1, ONECUT1, HPRT1, HSF4, DNAJB2, HSPA4, IGF1R, IHH, IL1RAP, ILK, IMPDH2, INS, INPPL1, INSIG1, EIF3E, IRAK1, ISG20, ITGA5, ITGB1, KCNA1, KCNA3, KCNA4, KCNC2, KCND2, KCND3, KCNJ2, KCNS2, KCNS3, KPNA3, IPO5, KRT5, LAMA3, LCAT, LIM2, LIPC, SMAD1, SMAD6, SMAD7, MYO1B, NUBP1, NRCAM, NUP98, NVL, OAT, OTX2, P2RX1, P2RX3, P2RX4, PA2G4, PAM, PCM1, CHMP1A, PLN, PPID, PPP2R1A, PPP2R1B, PPP5C, PPP6C, PRKAA1, PRKAR1A, PRKCI, PSMD4, PTEN, PTK2, PVR, PEX19, PEX5, RAB1A, RAB5A, RAC3, RAD51, RAD51C, RAD51B, RAD51D, RAF1, RAN, RAP1GAP, RAP2A, RB1, REST, RFX3, RPGR, RPL3, RPL3L, RPL5, RPL10, RPL24, RPL34, RPL35A, RPL38, RPS6, RPS19, RPS27, RRM1, RRM2, RSU1, RXRA, RXRG, RYK, SCO1, TRAPPC2, SELP, SET, SRSF1, SRSF5, SFSWAP, SGK1, SH3BGR, SHMT1, SHMT2, SLC9A1, SLC34A1, SLC22A1, SNAI1, SNAP25, SNCA, SNRPC, SNRPD1, SNRPE, SNRPF, SOD2, SRPK2, TRIM21, STRN, STXBP3, SURF6, SYT1, TAF7, TAF10, TAZ, TBCD, TNFRSF1A, TP73, HSP90B1, TRAF1, TRAF2, TRIP6, TSPY1, TUBG1, UBB, USP4, UVRAG, VBP1, VDAC2, XRCC2, YWHAZ, ZNF148, ZNF207, FZD5, CLPP, CHAF1B, HIST1H4I, PICALM, HIST1H2BL, HIST1H2BN, HIST1H2BM, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, NSMAF, CUL3, SMARCA5, OGT, CNTNAP1, IKBKAP, HAT1, GAS7, PRPF18, RRP1, RUVBL1, USO1, TP63, EIF3G, SRSF9, DGAT1, TRADD, RIPK1, PEX11A, LIN7A, SYNJ1, ARHGEF7, BSN, HIST1H3F, TAF1B, RPL14, CLDN12, CLDN1, LATS1, ATP6V0D1, PRPF3, SCAF11, ZW10, REPS2, DDX21, AURKB, SNAP29, SLIT2, RAB33A, SLC9A3R1, KIF3B, ZFYVE9, NRXN2, PEX16, DDX23, EIF2AK3, ATG5, ONECUT2, TBPL1, BAG5, SEC22B, GOSR2, SNCAIP, FEZ2, PDE4DIP, CEP135, NUP93, RAPGEF2, IFT140, SLK, EIF4A3, ATG13, TOMM20, SPOCK2, RB1CC1, SNAP91, REC8, RANBP9, AKAP9, FARP1, STAM2, ABCC4 |
1587 | GO:1901566 | 0.00 | 1.33 | 141.91 | 173 | 608 | organonitrogen compound biosynthetic process | ABAT, ACADM, AGTR2, AHCY, ALAD, ALAS2, ALDH3A2, ANG, ANGPT1, APP, ATF4, BCL3, BHMT, TSPO, CD28, CDA, CDK4, CDO1, CHAT, CHKB, CIRBP, CKM, COX15, CPOX, VCAN, CSPG4, CTH, DAPK3, DAZ1, DBH, DCN, DDX1, DDX6, DHFR, TYMP, EEF1B2, EIF1AX, EIF2B1, EIF4A1, EIF4E, EIF4G2, EIF5, EIF5A, ELAVL1, EPRS, ESD, EXT2, EXTL1, EXTL3, FAU, GPC4, FGF7, GAD1, GAPDH, GATM, B4GALT1, GGT7, GPC3, GLUD1, GOT2, GPT, GRB7, GSTZ1, HARS, HEXA, HMBS, HSPB1, IGF1, IDO1, EIF3E, LCAT, CAPRIN1, CNOT2, OAT, OAZ1, OAZ2, OMD, P2RX1, P2RX7, PA2G4, PAH, PCSK5, PCYT1A, PRKAA1, PRKD1, PSPH, PTAFR, PURA, PYCR1, QDPR, RARA, RBM4, UPF1, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL36AL, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS6KA1, RPS6KB1, RPS6KB2, RPS11, RPS19, RPS20, RPS27, RXRA, S100A9, SDC4, SHMT2, SMS, SNCA, SOX11, SRP9, SRP14, TNFRSF1A, TSC1, TUFM, TYMS, UCP1, UPP1, UROS, EIF4H, AIMP2, SLC25A16, NSMAF, SLC25A12, EIF4EBP3, DDX3Y, ALDH4A1, EIF3G, EIF4G3, B4GALT4, B4GALT3, EIF2B3, EIF2B2, EIF2S2, KYNU, RPL14, VAPB, B4GALT6, RPL23, GSTO1, EIF2AK3, CHST3, TBPL1, GTPBP1, HS2ST1, EIF5B, SDC3, EIF4A3, PTDSS1, RBM8A, HS3ST3B1, HS3ST1, ABCC5, ABCB6, COL4A3BP, TRAP1, EIF1 |
1588 | GO:0032268 | 0.00 | 1.33 | 122.04 | 149 | 547 | regulation of cellular protein metabolic process | ADAR, BIRC5, APLP2, ARR3, ATF4, BST2, BUB1B, TSPO, CCNE1, CD59, CDC25A, CDC25C, CDK2, CENPF, CHAD, CHEK1, CKS1B, COL6A3, CRY2, CRYBA1, CSNK2A1, CSNK2A2, CST6, DAPK3, DCN, DDX1, DDX6, DLG2, DLG3, DPEP1, DUSP1, ECM1, EIF2B1, EPHA2, EIF4A1, EIF4E, EIF4G2, EIF5, SERPINB1, EP300, EPHB1, EPRS, FGR, GAPDH, GAS1, GPC3, GNAQ, GP1BA, GPX1, GRB7, HHEX, HRC, HRG, HSPB1, IL10, EIF3E, ITIH1, ITIH4, KNG1, LIMK1, CAPRIN1, SMAD1, SMAD6, CNOT2, PA2G4, PRDX1, SERPINE1, SERPINA5, PCP4, SERPINF1, SERPINA4, SERPINB5, SERPINB9, SERPINB13, SERPINI2, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PTPN6, PTPRJ, PTPRR, PURA, PZP, RAC2, RAD23B, RAD51, RAG1, RAN, RARA, RBM4, RENBP, UPF1, RPL38, RPS6KA1, SERPINB4, SET, SLPI, SNRNP70, SPINK1, SPOCK1, SRP9, TRIM21, STYX, TAF7, SERPINA7, NR2F2, HSP90B1, TSC1, TSG101, USP4, UVRAG, VIL1, EIF4H, ZNF207, AKAP1, GFI1B, IKBKAP, EIF4EBP3, EIF3G, EIF4G3, SERPINB7, TNFSF14, EIF2B3, EIF2B2, SOCS3, DIRAS3, USP14, ZW10, SOCS6, SLIT2, SLC9A3R1, ATG5, TMEM59, BAG5, EIF5B, KDM4A, NUAK1, RBM8A, HDAC6, RANBP9, FEM1B, TRAP1, ATP6AP2, FARP1, RNF41, EIF1, CTDSPL, SPRY1 |
1589 | GO:0060255 | 0.00 | 1.33 | 114.80 | 140 | 544 | regulation of macromolecule metabolic process | ACACB, APLP2, ARF1, ARR3, BBS4, BST2, BUB1B, TSPO, C7, CD59, CDC25A, CDC25C, CHAD, CKS1B, COL6A3, CRYBA1, CST6, DDX6, DLG2, DLG3, DPEP1, EIF2B1, EPHA2, EIF4A1, EIF4E, EIF4G2, EIF5, SERPINB1, EPHB1, EPRS, FGR, FLOT2, FUT8, G6PC, GAPDH, GAS1, GCGR, GFAP, GHRHR, GHSR, GNAQ, GNAS, GP1BA, GPX1, GRB7, HRC, HRG, INPPL1, EIF3E, ITGAV, ITIH1, ITIH4, KCNQ1, KNG1, LIMK1, CAPRIN1, NUP98, PRDX1, SERPINA5, PCP4, SERPINF1, CFP, SERPINA4, SERPINB5, SERPINB13, SERPINI2, PPP2CB, PPP2R1B, PPP2R2A, PPP2R5D, PRG2, PTPN6, PTPRJ, PTPRR, PZP, RAC2, RAD23B, RAG1, RAG2, RANBP2, RENBP, RPL38, SORT1, SERPINB4, SFTPD, SLPI, SPINK1, SPOCK1, SRP9, STYX, SERPINA7, TOP1, HSP90B1, TSN, TSC1, USP4, UTY, UVRAG, VIL1, EIF4H, YWHAZ, NUP214, AAAS, AKAP1, NSMAF, FKBP6, EIF4EBP3, DDX3Y, EIF3G, EIF4G3, TNFSF14, DLK1, EIF2B3, EIF2B2, SOCS3, DIRAS3, USP14, ZW10, SOCS6, SLIT2, SLC9A3R1, LIPG, ATG5, TMEM59, BAG5, APBA3, NUP155, EIF5B, NUP93, KIAA0141, NUAK1, RANBP9, FEM1B, TRAP1, ATP6AP2, FARP1, EIF1, PRG4, CTDSPL, SPRY1 |
1590 | GO:0030036 | 0.05 | 1.33 | 44.78 | 55 | 191 | actin cytoskeleton organization | ACTN1, ADD1, ANG, ARF1, ARHGDIB, BCR, BST2, CAPG, CTNNA1, DIAPH1, DIAPH2, DPYSL3, EFNA5, EMP2, EPB41, EPB41L2, EPHA5, FGD1, GHSR, GRB2, HRG, ICAM1, ILK, INPPL1, LLGL2, ATXN3, MYO1B, PAM, PRKCE, PRKCI, RAC2, RAC3, RAN, CCL21, FSCN1, HSP90B1, CLRN1, VIL1, SORBS2, GAS7, DYNLL1, LATS1, ARHGEF2, PDLIM7, TRIP10, SLIT2, SLC9A3R1, PICK1, BCAR1, ARHGEF11, ARPC5, ARPC1B, ACTR2, ARPC2, ABI2 |
1591 | GO:0044255 | 0.00 | 1.31 | 133.29 | 161 | 564 | cellular lipid metabolic process | ABCA1, ABCA4, ACACB, ACADM, ACADS, ADH5, AGTR1, ABCD1, ALDH1A3, ALDH3A2, ALOX15B, ANG, ANXA1, APOH, ARF1, ARSA, STS, ARSD, ARSE, ARSF, BAX, OPN1SW, C3, DAGLA, CAT, CAV3, CBR1, CCNC, CD36, CHAT, AKR1C4, CHKB, CLPS, CNR1, CPS1, CPT1B, CPT2, CRAT, CRH, CSF1R, CTGF, CYP2A6, CYP2A13, CYP2F1, CYP3A4, DBI, DPEP1, ECH1, EPHA8, FAAH, FABP2, FABP7, PTK2B, FDFT1, FDPS, GPC4, FGF7, FGFR3, FGR, FLT1, FLT3, G6PC, GALC, GATA6, OPN1MW, GGT7, GHSR, GK2, GPC3, GM2A, GMDS, GPD2, GPLD1, GPX1, HEXA, HEXB, HMGCR, HMGCS2, HPGD, HTR2C, IDH1, INPP1, INS, INPPL1, INSIG1, IVD, KIT, LCAT, LIPC, LIPE, LTA4H, OXCT1, P2RX1, P2RX7, PAM, PCK1, PCYT1A, PDK4, PEX7, PEX13, PIK3C2B, PI4KA, PIP4K2A, PPP2R1A, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKAR2B, PRKD1, PSAP, PTEN, PTGIS, PTGS1, PTK2, ABCD3, RAC1, RBP1, RBP2, OPN1LW, RXRA, ACSM3, CCL21, SDC4, SFTPB, SLC12A1, SMARCD3, SNCA, UAP1, SRD5A1, SREBF1, STAT5B, TAZ, TBL1X, TNFRSF1A, NR1H2, PDHX, ACOX3, NSMAF, PIK3R3, AGPS, AKR1C3, DGAT1, B4GALT4, PEX11A, DPM2, INPP4B, SYNJ1, RGN, VAPB, KLF4, LIPG, EIF2AK3, PIGL, MPDU1, SDC3, PTDSS1, GNE, PIGK, COL4A3BP, DHRS9 |
1592 | GO:1901135 | 0.00 | 1.31 | 123.29 | 149 | 526 | carbohydrate derivative metabolic process | ABCA1, ABO, AMPD1, ANGPT1, ARCN1, ARSA, STS, ARSD, ARSE, ARSF, ART1, ATP2B2, AVPR2, BAX, BMPR2, CACNB4, CALM3, CANX, CD44, CD59, COL11A1, COPA, CRH, CSNK1D, VCAN, CSPG4, DAD1, DCN, DYNC1H1, DRD3, DRD5, LPAR1, EDNRA, EXT2, EXTL1, EXTL3, PTK2B, GPC4, FSHR, FUT6, FUT8, FZD2, G6PC, GALC, GALR1, GALNS, GCG, B4GALT1, GHRHR, GK2, GPC3, GM2A, GMDS, GNAS, GOLGA2, GOLGB1, GPD2, GPLD1, GRIA1, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GUCY2D, HEXA, HEXB, HGF, HTR2C, IDS, IDUA, IFNG, IHH, ITIH1, ITIH4, KIT, LIPC, MGAT2, MGAT3, NTHL1, NTRK2, OMD, OVGP1, P2RY11, PALM, PDE4B, PDE8A, PFAS, CFP, PIM1, PPP6C, PRKCSH, PSAP, RAB1A, RAF1, RCVRN, RENBP, RPE, RRM1, RRM2, CCL21, SDC4, TRAPPC2, SHMT1, SLC2A4, SLC9A1, SORD, UAP1, UNG, VEGFB, VIP, VIPR2, WFS1, TUSC3, USO1, PDE5A, DYNLL1, GALNT4, B4GALT4, B4GALT3, B3GALT2, DPM2, MBD4, COPB2, B4GALT6, COG1, CHST3, AKAP6, PIGL, TBPL1, MPDU1, GOSR1, TMEM59, SEC22B, GABBR2, GOSR2, AKAP12, GUCA1C, HS2ST1, SDC3, PTDSS1, SPOCK2, XYLB, HS3ST3B1, HS3ST1, GNE, PIGK, ABCC5, CHST4 |
1593 | GO:0044283 | 0.03 | 1.31 | 62.58 | 76 | 266 | small molecule biosynthetic process | ABAT, ACACB, ACADM, AHCY, ALDH1A3, ALOX15B, ANXA1, ASL, ASS1, BHMT, CBR1, CDO1, CHAT, AKR1C4, CHKB, CPS1, VCAN, CSPG4, CTH, CYP3A4, CYP8B1, CYP11B1, DCN, DHCR7, DHFR, CYB5R3, PTK2B, FDFT1, FDPS, FGF7, FSHB, GAD1, GATM, GGT7, GLUD1, GPT, HMGCR, HMGCS2, HPGD, HRH1, IFNG, IDO1, INSIG1, LCAT, LDHC, LIPC, LTA4H, NTSR1, OAT, PAH, PCYT1A, PDK4, PRKAA1, PRKAG1, PSPH, PTAFR, PTGIS, PTGS1, ABCD3, PYCR1, RBP1, REST, ACSM3, SHMT1, SHMT2, SNAI1, SNCA, SREBF1, NR1H2, UROS, CNBP, AKR1C3, ALDH4A1, KYNU, NR1H4, DHRS9 |
1594 | GO:0090304 | 0.00 | 1.30 | 646.37 | 738 | 2735 | nucleic acid metabolic process | ABCA2, ABL1, ACTL6A, ACTN1, ACVR2B, ACVRL1, ADAR, AEBP1, AGTR2, NR0B1, ALK, ALX3, ANG, ANXA1, ANXA3, APAF1, XIAP, BIRC5, APP, PHOX2A, ARNT, ARNTL, ASCL1, ASCL2, ATF4, RERE, ATR, ATRX, BACH1, BARD1, BAX, BCL3, BICD1, PRDM1, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTK, BYSL, CAMK2A, CAT, RUNX2, CBL, CCNB1, CCNC, CCNE1, CCNT2, CD3D, CD28, CD86, TNFSF8, CD36, CDK11B, CDC25A, CDC25C, CDH1, CDK2, CDK8, CDKN1A, CDX2, CEBPE, CENPB, CENPF, CHD2, CHD4, CHEK1, CHUK, CLU, CLK1, CLK3, CLNS1A, COL1A1, COX6A1, COX6B1, COX7C, COX8A, CREB1, CRX, CRY2, CSNK1D, CSNK2A1, CSNK2A2, CSTF3, CTGF, CTH, CTNND2, DAPK3, DCN, DDX1, DDX5, DDX6, DDX10, DFFA, DHFR, DKC1, DLX5, DNASE1, DNASE1L1, DNASE1L2, DNASE1L3, DNM2, DNMT1, DNMT3B, DNTT, DRD3, ARID3A, RCAN1, TSC22D3, DUSP1, E2F6, E4F1, EBF1, TYMP, ECM1, EDA, S1PR1, EFNA1, EGR2, EGR3, EGR4, EIF4A1, EIF4E, ELAVL2, ELK1, EMX1, EMX2, EN1, EP300, EPHA5, EPRS, EYA4, ERCC3, ERCC4, ERCC6, ERF, ERG, ESRRG, ETS1, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA2, EZH1, F2R, FANCE, PTK2B, FANCB, FANCF, FANCG, FAU, FBN1, EFEMP1, FEN1, FGF4, FGF7, FGFR3, AFF2, FSHB, NR5A2, FZD2, GALR1, GATA4, GATA6, GCG, KAT2A, GDF9, GPC3, GNAS, GPX2, GSC2, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, HARS, HBE1, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIP1, HIVEP2, HLF, HMGN1, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HNRNPC, HOXC10, HOXC11, HOXD8, HOXD9, HOXD10, HOXD12, HSF4, ICAM1, IFI16, SP110, IFNA2, IFNG, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL10, ILK, ING2, INS, INSIG1, EIF3E, IRAK1, IRAK2, IRF1, IRF5, ISG20, ISL1, JARID2, JUN, JUND, KCNK2, KIT, KPNA1, KPNA2, LMO1, LTF, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MEOX2, KITLG, MGMT, CIITA, ATXN3, AFF1, FOXO4, PPP1R12A, DRG1, TONSL, CNOT2, CNOT4, YBX1, NTHL1, NTRK3, NUP98, NVL, OAS3, ORC1, ORC2, ORC4, OTX1, OTX2, OVOL1, PA2G4, PRDX1, SERPINE1, PAM, PAX3, PAX9, PCBP2, PCK1, PCNA, CHMP1A, PDE8A, PGR, PHF2, PIM1, PPID, PPP1R8, PPP2R1A, PPP2R2A, PPP4C, PPP5C, PRIM2, PRKAA1, PRKAG1, PRKAR1A, PRKCI, PRKD1, PRKCQ, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PTAFR, PTEN, PTGIS, PTMA, PTMS, PURA, RAC1, RAD21, RAD23B, RAD51, RAD51C, RAD51B, RAD51D, RAF1, RAG1, RAG2, RAN, RANBP2, RARA, RARB, RB1, RBBP6, RBL2, RBM4, RBMS1, RBMS2, UPF1, DPF2, REST, REV3L, RFC3, RFC4, RFC5, RFX1, RFX3, RFXAP, RGS12, RHEB, RLF, RNASE1, RNASE2, RNASE6, RNF6, RP9, RPA2, RPA3, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS6KA1, RPS11, RPS19, RPS20, RPS27, RRM1, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A11, S100A12, SALL1, SATB1, XCL1, TRAPPC2, SET, SETMAR, SFPQ, SFRP5, SRSF1, SRSF5, SRSF7, SFSWAP, SGK1, SHC1, SIM2, SIX3, SLC9A1, SMARCA1, SMARCA2, SMARCA4, SMARCD3, SMARCE1, SUMO3, SNAI1, SNAPC3, SNCA, SNRNP70, SNRPA1, SNRPC, SNRPD1, SNRPE, SNRPF, SOD2, SOX3, SOX9, SOX10, SOX11, SP1, SP100, SPIB, SREBF1, SRF, SRPK2, SRY, TRIM21, SSRP1, STAT2, STAT3, STAT4, STAT5B, STAT6, SUPV3L1, TAF4B, TAF7, TAF10, TAL1, TBL1X, TBP, HNF1A, ZNF354A, NR2F1, NR2F2, KLF10, TMPO, TNFRSF1A, TNNI2, TOP1, TOP2A, TOP2B, TP73, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TSN, TSC1, TSG101, TTF1, TULP3, TNFSF4, TYMS, UBB, UBA7, UBE2D2, UBE2L3, UBE3A, SUMO1, UCP1, SCGB1A1, UNG, USP4, NR1H2, USF1, UVRAG, VAV1, WFS1, WNT1, WNT11, XPA, XRCC2, XRCC5, YY1, YWHAZ, ZFP37, ZFPL1, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF91, ZNF99, ZNF124, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZXDA, PRDM2, FZD5, AIMP2, ARHGEF5, NUP214, FOSL1, FGF23, AAAS, CDK2AP1, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, RBM10, KDM5C, SMC1A, USP9Y, HIST1H4I, PICALM, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, CUL4A, CUL3, CUL2, KLF11, SMARCA5, FKBP6, OGT, PARG, IKBKG, IKBKAP, HAT1, GAS7, COPS3, PIR, BLZF1, CDC14B, PRPF18, RRP1, KHSRP, STK16, RGS20, RUVBL1, KLF7, TP63, RNASET2, CHRD, DDX3Y, DYNLL1, SRSF9, TRADD, EED, RIPK1, RIPK2, SAP30, HESX1, ALKBH1, PER3, TAX1BP1, BUD31, HERC2, PHOX2B, MBD4, HIST1H3F, HIST1H2AG, RPS6KA4, TNFSF18, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, RPL14, USP2, RGN, PDLIM1, SMC3, PRPF3, CBFA2T2, DYRK1B, CTDP1, EXO1, SCAF11, ARHGEF2, DDX21, AURKB, CCPG1, ITGB1BP1, ZNF235, KLF4, COPS2, TRIP11, HMGN3, GTF3C5, GTF3C4, GTF3C3, EFTUD2, RPL23, RECQL5, ZRANB2, SNRNP40, DDX23, HAND1, ZNF264, EIF2AK3, FHL5, PICK1, IL27RA, ATG5, ONECUT2, LITAF, TBPL1, ZNF254, CHD1L, GTPBP1, CLOCK, SOX13, RBM39, RNF14, NUP155, ZNF516, KDM4A, VGLL4, NUP93, BZW1, KIAA0391, DHX34, ST18, ZNF646, SETD1A, ZFYVE16, EIF4A3, TATDN2, RNF40, RB1CC1, ARHGEF11, GINS1, ZEB2, ZBTB24, ZNF518A, SMG7, RNF10, ZBTB5, DCLRE1A, RBM8A, USP3, NR1I3, NR1H4, NR1D2, RBX1, REC8, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, PDCD7, RAD50, ZNF263, G3BP1, SUGP2, ZNF256, RNF41, PSMD14, OLIG2, DENND4A, IRX5, RAMP3 |
1595 | GO:0007264 | 0.04 | 1.29 | 59.98 | 72 | 259 | small GTPase mediated signal transduction | ABL1, ACTB, BIRC5, KLK3, TRIM23, ARF1, ARF5, ARL1, ARL2, BUB1B, KRIT1, CDC20, CDC25C, CDH1, CENPA, CENPE, CENPF, CTNNA1, CYBA, DIAPH1, DIAPH2, CTTN, CENPI, KIF5A, PPP1R12A, PPP1R12B, NUP98, RAB1A, RAB3B, RAB4A, RAB5A, RAB5B, RAB6A, RAB27A, RABIF, RAN, RANBP2, RANGAP1, RHEB, RPS27, CLIP1, SRF, YWHAZ, RND2, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, BCAR3, HIST1H3F, DIRAS3, ZW10, AURKB, RAB33A, RAB9A, RAB36, CKAP5, SH2D3C, SH2D3A, ARPC5, ARPC1B, ACTR2, ARPC2, ARL4A, ARFRP1 |
1596 | GO:0005975 | 0.01 | 1.28 | 107.37 | 128 | 457 | carbohydrate metabolic process | ABO, ALDOC, ARCN1, ART1, ATF4, CACNA1A, CALM3, CANX, CD44, CD59, CLN5, COPA, CPS1, CSNK1D, VCAN, CSPG4, CYB5A, DAD1, DCN, CYB5R3, DYNC1H1, ENO2, EXT2, EXTL1, GPC4, FUT6, FUT8, G6PC, GAA, GALC, GALE, GALK2, GALNS, GAPDH, B4GALT1, GK2, GPC3, GM2A, GMDS, GOLGB1, GOT2, GPD2, GRIA1, GYS2, HEXA, HEXB, ONECUT1, IDH1, IDH3A, IDS, IDUA, INPP1, INPPL1, KCNJ11, LDHC, MAN2B1, MDH2, MGAT2, MGAT3, NUP98, OMD, OGDH, OVGP1, PCK1, PCK2, CFP, PHKA2, PHKB, PHKG1, PPP2R5D, PPP6C, PRKACB, PRKACG, PRKCSH, PTEN, PYGB, PYGM, RAB1A, RPE, SDC4, TRAPPC2, SLC2A3, SLC2A4, SLC2A5, SLC5A2, SLC9A1, SORD, UAP1, SPAM1, UBB, UGT2B7, USF1, VEGFB, TUSC3, NUP214, AAAS, PARG, SLC25A12, USO1, DYNLL1, GALNT4, B4GALT4, B4GALT3, B3GALT2, DPM2, SYNJ1, MGAM, PAPSS1, COPB2, B4GALT6, COG1, GSTO1, CHST3, MPDU1, GOSR1, SEC22B, GOSR2, NUP155, HS2ST1, SDC3, NUP93, XYLB, HS3ST3B1, HS3ST1, GNE, ABCC5, CHST4, SLC25A13 |
1597 | GO:0051301 | 0.03 | 1.28 | 72.87 | 87 | 310 | cell division | ANXA11, ATRX, BBS4, BCL2L1, BMP4, BRCA2, ZFP36L2, BUB1B, CALM3, CCNB1, CCNE1, CCNF, CCNG2, CCNT2, CDC20, CDC25A, CDC25C, CDC27, CDK2, CDK3, CDK4, CDK6, CENPE, CENPF, CHEK1, CKS1B, CSNK2A1, CSNK2A2, DAPK3, DIAPH2, DUSP1, E4F1, ETV5, FGFR3, GNAI1, GOLGA2, GPR3, ING2, KIT, LLGL2, NUMA1, CHMP1A, SEPT5, PRKAR1A, RAD21, RALA, RAN, RPS3, TACC1, DYNLT3, DYNLT1, TOP1, TOP2A, TSG101, TTK, UVRAG, VRK1, ZNF207, TUBA1A, USP9X, SMC1A, FZD7, RUVBL1, TP63, NUMB, CDC23, CDC16, RNF8, USP8, LATS1, SMC3, CCNB2, CTDP1, ARHGEF2, ZW10, RECQL5, BCAR1, MAD2L1BP, CKAP5, CUL7, ARHGEF11, KLHL21, DCLRE1A, PDCD6IP, SMC4, ACTR2, KIF20A |
1598 | GO:0045936 | 0.05 | 1.28 | 59.42 | 71 | 252 | negative regulation of phosphate metabolic process | ABL1, ADAR, ANGPT1, BAX, BMP4, CALM3, CAV3, CCNB1, CDKN1A, CHAD, CRY2, CRYBA1, DCN, DLG2, DLG3, DUSP1, DUSP5, FBLN1, GNAQ, GP1BA, RAPGEF1, HHEX, HMGCR, FOXA2, HSPB1, IGF1, IGF1R, IGFBP3, ILK, INHA, JUN, SMAD3, SMAD6, SMAD7, NTRK3, P2RX7, PCP4, PPP2R1A, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRPSAP1, PTEN, PTPN6, PTPRJ, PTPRR, RANBP2, RB1, SPINK1, TAF7, NR2F2, TP73, AKAP1, CUL3, OGT, DYNLL1, SOCS3, RGN, LATS1, ITGB1BP1, SOCS6, KLF4, SLIT2, SLC9A3R1, BAG4, RANBP9, FARP1, CTDSPL, SPRY1 |
1599 | GO:0072657 | 0.05 | 1.28 | 62.91 | 75 | 267 | protein localization to membrane | BAD, BAX, BCL2L1, BSG, CAV3, CDH1, DPP6, EPHA2, EMP2, FAU, FLOT2, FYB, GDI1, GOLGA4, HSPA4, IFNG, ITGB1, PALM, PRKCI, PEX19, PEX5, RAC1, RAP2A, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, CLIP1, SLC12A1, SRP9, SRP14, TNFRSF1A, TULP1, TULP2, TULP3, SUMO1, VIL1, WRB, YWHAZ, OGT, BLZF1, NUMB, DYNLL1, VAMP8, LIN7A, AP3D1, RPL14, RPL23, SLC9A3R1, PEX16, TMEM59, BAG4, RAPGEF2, C2CD5, BCL2L11, ARFRP1, RAMP3 |
1600 | GO:0006518 | 0.02 | 1.28 | 93.40 | 111 | 396 | peptide metabolic process | AEBP1, ANG, APP, ATF4, BCL3, CD28, CDK4, CIRBP, CLU, TPP1, CTNS, CTSH, DAPK3, DAZ1, ACE, DDX1, DDX6, DPEP1, EEF1B2, EIF1AX, EIF2B1, EIF4A1, EIF4E, EIF4G2, EIF5, EIF5A, ELAVL1, EPRS, PTK2B, FAU, FSHB, GAPDH, GGT7, GPX1, GRB7, GSTZ1, HARS, HSPB1, IDH1, IGF1, EIF3E, LTA4H, CAPRIN1, CNOT2, PA2G4, PAM, PTAFR, PURA, RARA, RBM4, UPF1, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL36AL, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS6KA1, RPS6KB1, RPS6KB2, RPS11, RPS19, RPS20, RPS27, RXRA, S100A9, SOX11, SRP9, SRP14, TSC1, TUFM, UCP1, EIF4H, AIMP2, SLC25A16, PICALM, SLC25A12, EIF4EBP3, DDX3Y, EIF3G, EIF4G3, EIF2B3, EIF2B2, EIF2S2, RPL14, PCSK7, RPL23, GSTO1, EIF2AK3, GTPBP1, EIF5B, EIF4A3, RBM8A, TRAP1, ATP6AP2, SLC25A13, SLC25A15, EIF1 |
1601 | GO:0044238 | 0.04 | 1.28 | 74.98 | 89 | 387 | primary metabolic process | ABCA4, ACADM, ACADS, ABCD1, ALDH1A3, ALDH3A2, ALOX15B, ARG1, ARG2, ASS1, AUH, BCKDHA, DAGLA, CBR1, CDO1, CHAT, AKR1C4, CHKB, CKM, CLPS, CPT1B, CPT2, CRAT, CYP2A6, CYP2A13, CYP2F1, CYP3A4, CYP8B1, CYP11B1, DBI, DBT, SARDH, ECH1, FAAH, FABP2, FABP7, FDFT1, FDPS, GATM, GLDC, GLUD1, GPT, GSTZ1, HMGCS2, HNMT, HPGD, HSD11B1, IL1RN, IDO1, IVD, OAT, OXCT1, PCYT1A, PEX7, PEX13, PIK3C2B, PI4KA, PIP4K2A, PSPH, PTGS1, ABCD3, PYCR1, QDPR, RBP1, RBP2, ACSM3, SLC6A6, SLC7A4, SLC10A1, SLC12A1, SLCO1A2, SMS, SRD5A1, SUOX, TAT, TYR, TRPV1, SLC7A5, ACOX3, DDO, AGPS, ALDH4A1, DGAT1, PEX11A, INPP4B, SNX17, PTDSS1, DHRS9, DHRS2 |
1602 | GO:0044702 | 0.02 | 1.27 | 109.84 | 130 | 475 | single organism reproductive process | NR0B1, BIRC3, ARHGDIB, ATRX, BAD, BBS4, BMPR1A, BOK, BRCA2, BRDT, CASP5, CCNB1, CD9, CDC20, CDC25C, CDK2, COL9A3, CXADR, CYLC1, CYLC2, DAZ1, ACE, DIAPH2, DNM2, DUSP1, PHC2, EMP2, ERCC4, ETV5, PTK2B, FBLN1, GATA4, GATA6, B4GALT1, GLRA1, GOLGA2, GPR3, HIST1H1T, HIST1H1A, HEXB, HOXD9, HOXD10, HPGD, IDH1, IL1A, IL1R1, ING2, KRT9, SMAD1, SMCP, NUMA1, ODF1, OVGP1, OVOL1, P2RY2, SERPINA5, PCSK5, PPP2R1A, PRKACB, PRKACG, PRKAG1, PRKAR1A, RAD21, RAD23B, RAD51, RAD51C, RAD51B, RAD51D, RPS6KB1, RRM1, SALL1, SBF1, SMARCA2, SMARCA4, SOX3, SPAG4, SPAM1, SPINK1, SRD5A1, SRY, STYX, TAF4B, TBP, TOP2A, TOP2B, NR2C2, TRPC3, TSPY1, TUBG1, UBB, SCGB1A1, VIP, ZAN, XRCC2, YY1, ZNF35, ZNF148, DNALI1, AAAS, USP9X, SMC1A, USP9Y, TPST2, FKBP6, RUVBL1, AKR1C3, PDE5A, DYNLL1, ADAM15, EIF2S2, HERC2, RNF8, RGN, SMC3, FAM50A, EXO1, ZW10, PICK1, ADAMTS2, TBPL1, CLOCK, SPAG6, SPATA2, REC8, BCL2L11, SMC4, ACTR2, RAD50, AKAP9, IRX5 |
1603 | GO:0044712 | 0.02 | 1.27 | 106.49 | 126 | 458 | single-organism catabolic process | ABAT, ACACB, ACADM, ACADS, ACTL6A, ADH5, AHCY, ABCD1, ANXA5, APOH, ARG1, STS, ASL, AUH, BCKDHA, BLVRA, BNIP3L, TSPO, DAGLA, CD44, CDA, CDO1, CLPS, CNR1, COX8A, CPT1B, CPT2, CRAT, CSNK2A2, CTH, CYP2A6, CYP3A4, DBT, ACE, DPEP1, TYMP, ECH1, CTTN, ESD, FAAH, FABP2, FABP7, FANCF, GABRA5, GAD1, GALC, GALNS, KAT2A, GLDC, GLUD1, GOT2, GPLD1, GPT, GSTZ1, HBA2, HNMT, HP, DNAJB2, IDH1, IDO1, INPP1, IVD, KCNK3, LIPC, LIPE, ATXN3, NTSR1, OAT, OMD, OXCT1, P2RX5, PRDX1, PAH, PEX7, PEX13, PRKACB, PRKACG, PRKCE, PSMC1, PSMC2, PSMC3, PSMC4, PTEN, ABCD3, QDPR, RENBP, SHMT1, SLC9A1, SLCO1A2, SLC22A3, SNCA, SNRPD1, SNRPF, SREBF1, STAT2, SUOX, TAT, NR2C2, HSP90B1, UBB, WFS1, TRIM25, ZBTB17, ZNF189, RNF103, FZD5, FGF23, CHAF1B, ACOX3, DDO, RUVBL1, AKR1C3, ALDH4A1, SYNJ1, KYNU, USP14, LIPG, CHST3, ATG5, NUP93, ATG13, SNX17, PHYHIP, TOMM20, FGFBP1, HDAC6 |
1604 | GO:0044711 | 0.01 | 1.27 | 128.86 | 152 | 556 | single-organism biosynthetic process | ABCA1, ADSS, NR0B1, AK1, AK2, ALDH3A2, AMPD1, AMPD2, ANG, ANGPT1, ARF1, ATP1A1, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, ATP6V0A1, ATR, AVPR2, BMP4, C3, CALM3, CDA, COL1A1, CREB1, CRH, CTGF, DKC1, DRD3, DRD5, TYMP, LPAR1, EDNRA, EIF5A, ESD, EXT2, EXTL1, EXTL3, F2, F2R, GPC4, FSHR, FUT8, GALR1, B4GALT1, GHRHR, GPC3, GMDS, GNAS, GPLD1, GSTZ1, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GYS2, GUCY2D, HARS, HEXA, HEXB, HNRNPC, HSD11B1, HTR2C, IDH1, IGF1, IGF2, IHH, IMPDH1, IMPDH2, INPPL1, MGAT2, CIITA, NTRK2, OMD, P2RX1, P2RX7, P2RY11, PALM, PEX7, PFAS, PHKG1, PIK3C2B, PI4KA, PIP4K2A, PRKD1, PRKCQ, PRPSAP1, PTEN, RAF1, RCVRN, REV3L, RRM1, RRM2, SDC4, UAP1, SRD5A1, STAT3, TAZ, TNFRSF1A, TUFM, TYMS, UBB, UBA7, UPP1, VIP, VIPR2, WFS1, TRIM25, PDHX, NSMAF, DYRK2, CUL4A, PIK3R3, AGPS, DGAT1, B4GALT4, B4GALT3, B3GALT2, SERPINB7, SUCLG1, DPM2, INPP4B, SYNJ1, PAPSS1, AURKB, VAPB, B4GALT6, CHST3, AKAP6, PIGL, ADAMTS3, TBPL1, MPDU1, GABBR2, AKAP12, GUCA1C, HS2ST1, SDC3, PTDSS1, EPM2AIP1, XYLB, HS3ST3B1, HS3ST1, RBX1, GNE, PIGK, ABCC5, COL4A3BP, RAD50 |
1605 | GO:0046907 | 0.04 | 1.26 | 75.43 | 89 | 332 | intracellular transport | ABCA1, ABCA2, ACACB, ABCD1, AMPH, APP, ATP5C1, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5I, KIF1A, BBS4, BCL2L1, BICD1, BSG, BST2, CACNA1A, CAMK2A, CANX, AP2S1, CNP, CPT1B, CPT2, CTTN, EYA2, FTL, GDI1, GNAS, IFIT1, IL13RA2, ITGB1, KIF5A, KIT, LTBP2, MYO1B, OPA1, PALM, CHMP1A, PFN2, SEPT5, PRKCI, RAB27A, RANBP1, RPGR, CLIP1, RTN2, S100A13, SNAP25, STXBP2, SYN1, SYT1, SYT5, TNNC1, UBB, UCP1, UVRAG, LAT2, TUBA1A, PICALM, UXT, OGT, SLC25A12, SSNA1, STX11, LIN7A, HERC2, ARHGEF2, RASSF9, SNAP29, KIF3B, PICK1, AKAP12, CLINT1, RIMS2, IFT140, DNAJC6, GOLGA5, HDAC6, PDCD6, TOM1, AP1M2, ATP9A, COL4A3BP, SLC25A13, SLC25A15, STAM2, RAMP3 |
1606 | GO:0045184 | 0.00 | 1.25 | 192.17 | 223 | 826 | establishment of protein localization | ABCA1, ACVR2B, ADAR, ARCN1, ARF5, ARL2, ARNTL, RERE, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, BAX, BBS4, BCL3, BNIP3L, BRCA2, BSG, BTF3, TSPO, VPS51, CACNA1A, CANX, CAV3, CBLB, CD3G, SCARB2, CD63, CDKN1A, CENPF, CHRM3, AP1S1, AP2S1, CLU, CNR1, COL1A1, COPA, CRP, CSE1L, DMBT1, DNM2, EFNA5, EGR2, EIF5A, CTTN, EPHA5, EPS15, FAU, FLOT2, FYB, GDI2, GFER, GLE1, GNAQ, GNAS, GOLGA4, HIST1H1B, FOXA2, HSPA4, HSPA9, IFIT1, RBPJ, IL1RN, ITPR1, JUN, KCNC2, KCNS3, KPNA2, KPNA3, KPNA4, LAMP2, LLGL2, LTBP2, NUP98, PRDX1, PALM, PAM, CHMP1A, PCSK5, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PTPRN, PTPRN2, PEX19, PEX5, RAB1A, RAB3B, RAB4A, RAB5A, RAB5B, RAB6A, RAB27A, RABIF, RAF1, RAN, RANBP2, RAP2A, RFX3, RPGR, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, CLIP1, RTN2, RYR2, S100A12, S100A13, SIX3, SLC12A1, SLC15A1, SNAP25, SRP9, SRP14, STAT3, STXBP2, STXBP3, STYX, SYT5, CNTN2, HNF1A, DYNLT1, TNFRSF1A, HSP90B1, TRAF2, VIP, WRB, SCG2, NUP214, AAAS, CLTCL1, FZD7, AP3B1, BLZF1, RGS20, USO1, SSNA1, AKR1C3, VAMP8, STX11, LIN7A, AP1M1, HERC2, AP3D1, SELENBP1, RPL14, SYT7, UNC119, ATP6V0D1, SEC22C, RABEP1, ARHGEF2, RASSF9, ZW10, COPB2, TRIP11, HMGN3, SNAP29, RPL23, RAB33A, RAB9A, ZFYVE9, COG1, PEX16, EIF2AK3, PICK1, ATG5, GOSR1, APBA3, ATP6V1G1, SEC22B, VPS26A, GOSR2, CLOCK, AKAP12, RAB36, NUP155, IPO13, NUP93, RIMS2, IFT140, ACAP1, ZFYVE16, SNX17, TOMM20, SNAP91, HDAC6, PDCD6IP, PDCD6, TOM1, AP1M2, KIF20A, ARFRP1, STAM2 |
1607 | GO:0030030 | 0.01 | 1.25 | 136.40 | 159 | 587 | cell projection organization | ACTB, ADAM10, ANGPT1, APP, ARAF, RERE, ATP2B2, TSPO, CACNB4, CALM3, CAMK2A, CAPG, CD72, CDH1, AP2S1, CLU, CNP, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2RB, CSNK1D, CSNK2A1, CSNK2A2, CTNNA1, DHFR, DLG3, DLX5, DNM1, EPYC, DUSP5, S1PR1, EFNA3, EFNA4, EFNB1, EGR2, EMP2, EMX1, EPHA5, EPHA8, ETV4, FGD1, FGF3, FGF4, FGF7, FGFR3, GFRA1, GRB2, GRIN2A, ONECUT1, HPRT1, IL2RA, INPPL1, ISL1, ITGA1, ITGA5, ITGA9, ITGAV, JUN, KIF5A, MARK3, KITLG, NUBP1, NTF4, NTN3, OTX2, PCM1, PPP5C, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTPRA, RAC3, RAF1, RASA2, RB1, RFX3, RPGR, RPL24, RPS6KA1, RXRA, RYK, SCN5A, SDC4, SHC1, STIL, SOS2, STRN, TBCE, DYNLT1, TOP2B, TRPC1, TRPC3, TRPC4, TRPC5, TSC1, TULP1, TYROBP, UBB, FGF23, USP9X, PICALM, CUL3, CNTNAP1, GAS7, KLF7, UNC5C, SSNA1, NUMB, DYNLL1, PEA15, NRP2, PHOX2B, RPS6KA4, ATP6V0D1, SNAP29, NRXN3, CHST3, ONECUT2, PSMF1, BAG4, NRG2, SPAG6, FEZ2, CROCC, ARHGEF11, RBX1, RANBP9, ARPC5, ARPC1B, ACTR2, AKAP9, RASA4, FARP1, PSME3, PSMD14, ABCC4 |
1608 | GO:0009058 | 0.03 | 1.25 | 101.92 | 119 | 478 | biosynthetic process | ABO, ARCN1, ART1, DAGLA, CANX, CD59, CDC25A, CDC25C, CKM, COMT, COPA, COX6A1, COX6B1, COX7C, COX8A, CSNK1D, CSTF3, DAD1, DBH, DYNC1H1, DNTT, EEF1B2, EIF1AX, FAU, FUT6, GK2, GOLGB1, GPX2, GRIA1, GTF3C1, GTF3C2, IL1RAP, IL18, MGAT3, NUBP1, DRG1, NUP98, OAZ1, OAZ2, ORC4, PRDX1, PCSK5, CFP, PPM1B, PPP5C, PPP6C, PRKCSH, PTMA, PTMS, QDPR, RAB1A, RAD51, RBMS1, RGS12, RHEB, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL36AL, RPL37, RPL37A, RPL39, RPL36A, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, SETMAR, SRSF1, SRSF5, SRSF7, SLC2A4, SLC22A2, SMS, SNRPE, SNRPF, SRP14, TAT, TOP1, UGT2B7, VEGFB, YWHAZ, AIMP2, TUSC3, NUP214, SLC25A16, AAAS, CDK2AP1, USO1, DDX3Y, SRSF9, GALNT4, EIF2S2, RPL14, DDX21, COPB2, GTF3C5, GTF3C4, GTF3C3, RPL23, COG1, ATG5, GOSR1, SEC22B, GTPBP1, GOSR2, NUP155, NUP93, ABCB6, CHST4 |
1609 | GO:0071702 | 0.00 | 1.24 | 260.43 | 300 | 1132 | organic substance transport | ABCA3, ABCA4, ABL1, ABL2, ACTL6A, ADAR, ALOX15B, ANG, ANGPT1, APOH, ARCN1, ARF1, ARF5, RERE, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, BARD1, BBS4, BMP4, BMPR1A, BNIP3L, BSG, BTF3, C3, VPS51, CA4, CANX, CASP5, CBLB, CD3G, SCARB2, CD58, CD63, CDH1, CDKN1A, CENPF, CHRM1, AP1S1, AP2S1, COL1A1, COPA, CRP, CSE1L, CSF1R, CSNK2A2, CTSK, DMBT1, DNM2, EDNRA, EGR2, EIF4E, EIF5A, CTTN, EPS15, F2R, FBLN1, FAU, FGR, FYB, G6PC, KAT2A, GDF9, GDI1, GDI2, GFER, GIF, GJB1, GPC3, GLE1, GM2A, GNAQ, GOLGA4, GPR26, HBA2, HCLS1, NRG1, HHEX, HNMT, HSPA4, HSPA9, IFIT1, IFNA2, IGF1, RBPJ, IL1A, IL13, ITGAV, ITGB1, JUN, KCNN4, KPNA1, KPNA2, KPNA3, KPNA4, IPO5, LAMP2, LLGL2, LTBP2, SMAD3, TONSL, NUP98, OAZ1, OAZ2, PAEP, PALM, PAM, SERPINA5, PCM1, CHMP1A, PCSK5, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PPID, PRKAA1, PRKCI, PSAP, PEX19, PEX5, RAB4A, RAB5A, RAB5B, RAB6A, RAB27A, RABIF, RAC2, RAN, RANBP2, RANGAP1, UPF1, RHAG, RHCE, RHD, RNASE2, RPGR, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS6KB1, RPS11, RPS19, RPS20, RPS27, CLIP1, RTN2, SORT1, S100A12, S100A13, CX3CL1, SFRP5, SRSF1, SRSF5, SRSF7, SIX3, SLC2A3, SLC2A4, SLC2A5, SLC4A1, SLC5A2, SLC9A1, SP100, SRP9, SRP14, STAT3, STXBP2, STYX, TAF7, SERPINA7, DYNLT1, HSP90B1, TRAF2, TSC1, TSG101, TNFSF4, UBE2L3, UPK3A, VIL1, YWHAZ, ZIC1, ZBTB17, FZD5, SCG2, ARHGEF5, NUP214, AAAS, AKAP1, SLC14A2, CLTCL1, BAP1, FZD4, FZD7, DYRK2, OGT, PIK3R3, AP3B1, BLZF1, KHSRP, RGS20, RUVBL1, USO1, SSNA1, AKR1C3, DYNLL1, VAMP8, STX11, PEA15, SRSF9, RIPK1, LIN7A, AP1M1, HERC2, AP3D1, SELENBP1, CDKL2, RPL14, UNC119, ATP6V0D1, SEC22C, RABEP1, IL1RL1, ARHGEF2, RASSF9, ZW10, ITGB1BP1, COPB2, TRIP11, SNAP29, RPL23, RAB33A, RAB9A, ZFYVE9, SLC22A8, COG1, PEX16, AKAP6, ATG5, SLC4A7, GOSR1, BAG4, APBA3, ATP6V1G1, SEC22B, VPS26A, GOSR2, AKAP12, RAB36, NUP155, IPO13, NUP93, IFT140, ACAP1, ZFYVE16, EIF4A3, ATG13, SNX17, CKAP5, TOMM20, C2CD5, ZC3H11A, OSBPL2, SMG7, SNAP91, FAM20B, RBM8A, HDAC6, PDCD6IP, PDCD6, TOM1, AP1M2, SAE1, ABCC5, ATP9A, COL4A3BP, KIF20A, ARFRP1, NUTF2, SLC35B1, STAM2, RAMP3 |
1610 | GO:0051128 | 0.03 | 1.24 | 109.95 | 128 | 480 | regulation of cellular component organization | ACTL6A, ANGPT1, APAF1, BIRC5, ARL2, ATR, AXL, BAD, ADGRB2, BAX, BCR, BICD1, BLK, BNIP3L, C3, CAPN6, CBL, CD28, CD36, CD63, CDC25C, CENPE, AP2S1, CREB1, CTSK, DCN, DKC1, DRD3, EIF5A, EPHA5, EPHB1, EPHB2, ETV5, FLT3LG, GCG, GHSR, GPC3, GPR3, GPR26, GRB2, HCLS1, HIP1, HNMT, IFNG, IGF1R, IGF2, IL1A, ISL1, ITGAV, JUN, LCAT, CNOT2, OXTR, SERPINE1, PAM, CHMP1A, PFDN2, PIP4K2A, PRKCE, PSMC1, PSMC2, PSMC3, PSMC4, RAB4A, RAB5B, RAB27A, RB1, UPF1, RNASE2, RPS3, CLIP1, SELE, SELP, SFPQ, SFTPD, SREBF1, SURF4, TAL1, HNF1A, DYNLT1, TPBG, TULP1, UBE2L3, SUMO1, VTN, YWHAZ, ZBTB17, ARHGEF5, FOSL1, GFI1B, CUL3, RUVBL1, DYNLL1, VAMP8, EED, HRK, TNFSF14, TNFSF10, SYNJ1, RPS6KA4, CDKL2, LATS1, RAB33A, NRXN3, GDF15, SEC22B, MAD2L1BP, SNCAIP, FRMPD4, ZFYVE16, ATG13, PIEZO1, SNX17, DLGAP5, RNF40, DNAJC6, ZEB2, C2CD5, SNAP91, FAM20B, PDCD6IP, BCL2L11, SAE1, ARPC5, ARPC1B, ACTR2, ABI2, RAMP3 |
1611 | GO:0006511 | 0.04 | 1.24 | 85.79 | 100 | 363 | ubiquitin-dependent protein catabolic process | ARAF, ARNTL, BUB1B, CAV3, CBL, CCNB1, CCNF, CDC20, CDC27, CDK2, CENPF, CLU, CSNK1D, CSNK2A1, CSNK2A2, DUSP1, PTK2B, UBE2K, DNAJB2, SMAD7, ATXN3, PCBP2, PPP2CB, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, RAD23B, RB1, RBBP6, RNF6, SKP1, SUMO3, TBL1X, HSP90B1, TSG101, TTC3, TTK, UBB, UBE2D2, UBE2H, UBE2L3, UBE3A, SUMO1, USP4, WFS1, WNT1, TRIM25, ZNF207, RNF103, GAN, USP11, USP9X, USP9Y, BAP1, CUL4A, CUL3, CUL2, CUL1, COPS3, CDC23, CDC16, HERC2, RNF8, USP14, USP2, USP8, ZW10, AURKB, UBE4A, PSMF1, BAG5, CLOCK, RNF14, RNF7, UBE3C, DLGAP5, RNF40, CUL7, KLHL21, USP3, RBX1, HDAC6, PSME3, PSMD14 |
1612 | GO:0043632 | 0.05 | 1.23 | 87.92 | 102 | 372 | modification-dependent macromolecule catabolic process | ARAF, ARNTL, BUB1B, CAV3, CBL, CCNB1, CCNF, CDC20, CDC27, CDK2, CENPF, CLU, CSNK1D, CSNK2A1, CSNK2A2, DUSP1, PTK2B, UBE2K, DNAJB2, SMAD7, ATXN3, PCBP2, PPP2CB, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMC1, PSMC2, PSMC3, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PTEN, PTK2, RAD23B, RB1, RBBP6, RNF6, SKP1, SUMO3, TBL1X, HSP90B1, TSG101, TTC3, TTK, UBB, UBA7, UBE2D2, UBE2H, UBE2L3, UBE3A, SUMO1, USP4, WFS1, WNT1, TRIM25, ZNF207, RNF103, GAN, USP11, USP9X, USP9Y, BAP1, CUL4A, CUL3, CUL2, CUL1, COPS3, CDC23, CDC16, HERC2, RNF8, USP14, USP2, USP8, ZW10, AURKB, UBE4A, PSMF1, BAG5, CLOCK, RNF14, RNF7, UBE3C, DLGAP5, RNF40, CUL7, KLHL21, USP3, RBX1, HDAC6, PSME3, PSMD14, ZMPSTE24 |
1613 | GO:2000112 | 0.00 | 1.22 | 302.74 | 344 | 1326 | regulation of cellular macromolecule biosynthetic process | ABCA2, ABL1, ACTL6A, AGTR2, ALK, ALX3, ANXA3, XIAP, APP, PHOX2A, ARNT, BMP1, BMP3, BMP8B, BMPR1A, BRDT, ZFP36L2, KLF9, BTF3, BTK, CAMK2A, CBL, CCNC, CCNE1, CCNT2, CD3D, CD28, CD86, TNFSF8, CDK11B, CDH1, CDK2, CDK4, CDK8, CEBPE, CENPB, CHD2, CHEK1, CHUK, CLU, COL1A1, CRX, CSNK2A1, CSNK2A2, CTH, CTNND2, DAZ1, DCN, DDX1, DDX6, DHFR, DLX5, DNM2, ARID3A, RCAN1, EBF1, ECM1, EDA, S1PR1, EGR2, EGR3, EGR4, EIF2B1, EIF4A1, EIF4G2, EIF5, EIF5A, ELAVL2, ELAVL1, ELK1, EMX1, EMX2, EPHA5, EYA4, ERCC3, ERCC6, ERG, ESRRG, ETS1, ETV4, ETV5, EVX1, EWSR1, EYA2, EZH1, F2R, FBN1, EFEMP1, FGF4, FGF7, FSHB, NR5A2, FZD2, GALR1, GATA4, GCG, KAT2A, GDF9, GPC3, GOLGA2, GSC2, GTF2I, GTF3A, BRF1, HEXB, HIP1, HIVEP2, HLF, HMGN1, NR4A1, HMX2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD10, HOXD12, HSPB1, ICAM1, SP110, IGF1, IGF2, IHH, IL1A, IL10, ILK, ING2, INS, INSIG1, IRF5, KIT, LTF, SMAD6, SMAD9, MAZ, MEOX2, KITLG, ATXN3, AFF1, FOXO4, PPP1R12A, NTRK3, ORC1, OTX1, OTX2, SERPINE1, PAM, PCK1, PCNA, PDE8A, PGR, PPP1R8, PPP2R1A, PRKAA1, PRKAR1A, PRKCI, PRKD1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PTAFR, PTEN, RAC1, RAD21, RAF1, RBBP6, RBL2, DPF2, RFX1, RFXAP, RLF, RNF6, RPL38, RPS6KA1, RPS6KB1, RPS6KB2, RRM2, RXRG, RYR2, S100A8, S100A9, S100A12, CCL21, TRAPPC2, SFSWAP, SGK1, SHC1, SLC9A1, SMARCA1, SMARCD3, SNAPC3, SOD2, SP1, SPIB, SSRP1, STAT2, STAT4, STAT5B, TAF4B, TAF10, HNF1A, ZNF354A, TMPO, TNFRSF1A, TNNI2, TOP2A, NR2C2, TRAF1, TRAF2, TRIP6, TULP3, TYMS, UBE2D2, UBE2L3, UBE3A, UCP1, USF1, VAV1, EIF4H, WNT1, ZFP37, ZFPL1, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF26, ZNF28, ZNF32, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF99, ZNF124, ZNF140, ZNF141, ZNF142, ZNF143, TRIM25, ZBTB17, ZNF155, VEZF1, ZNF180, ZNF207, ZNF223, ZNF225, ZNF229, ZNF232, ZXDA, PRDM2, FZD5, ARHGEF5, FOSL1, FGF23, ANP32A, ZNF239, DPF1, CHAF1B, USP9Y, PICALM, FZD4, FZD7, DYRK2, CUL2, SMARCA5, OGT, IKBKG, IKBKAP, GAS7, PIR, BLZF1, KHSRP, STK16, RGS20, RUVBL1, KLF7, CHRD, DYNLL1, EIF3G, EIF4G3, TRADD, RIPK1, RIPK2, EIF2B2, BUD31, PHOX2B, RPS6KA4, TNFSF18, BAZ1B, PDLIM1, DYRK1B, CTDP1, ARHGEF2, CCPG1, ITGB1BP1, ZNF235, HMGN3, ZRANB2, ZNF264, FHL5, ONECUT2, LITAF, TBPL1, SOX13, RBM39, RNF14, ZNF516, EIF5B, VGLL4, BZW1, ZNF646, SETD1A, ZFYVE16, RB1CC1, ARHGEF11, ZBTB24, ZNF518A, EPM2AIP1, RNF10, ZBTB5, RBM8A, RBX1, DMTF1, CASP8AP2, TRAP1, RNF41, EIF1, DENND4A, IRX5 |
1614 | GO:0051716 | 0.00 | 1.20 | 336.94 | 375 | 1720 | cellular response to stimulus | ABAT, ABCA4, ACPP, ACTB, ADRA1B, APLNR, ALK, ALOX15B, ANXA6, BIRC5, APLP2, KLK3, TRIM23, ARF1, ARF5, ARHGAP6, ARHGDIB, ARL1, ARL2, ARR3, ADGRB2, OPN1SW, BCR, BICD1, BLK, DST, BSG, BTK, BUB1B, C3, CAPN5, DAGLA, CACNA1A, CACNB4, CASQ1, CBLB, KRIT1, CD3D, CD3E, CD3G, CD4, CD5, CD7, CD8A, TNFSF8, CD37, CD59, CD72, ADGRE5, CD151, CDA, CDC20, CDC25C, CDH6, CDK4, CENPA, CENPE, CENPF, CHN1, CHN2, CHRM1, CHRM3, CHRNB2, CHRNB4, CLCN6, CLPS, CNR1, COL4A3, COL15A1, CLDN3, CR2, CRYBA1, CSNK1G3, CSNK2A1, CSPG4, CTF1, CTNND2, DGKB, DBH, DCC, DIAPH2, DMBT1, DNM1, DOK1, DRD3, RCAN1, DTNA, S1PR1, EFNA1, EFNA3, EFNA4, EFNB1, EIF2B1, EMP2, EPHA8, EPHB2, EPHB3, EPS15, ERG, EXT2, F2R, F2RL2, F10, FBLN1, EFEMP1, FCER2, FCGRT, GPC4, FGR, FLT3LG, FPR1, FPR3, CENPI, FYB, FZD2, GABRA4, GABRE, GABRG1, GABRR1, GABRR2, GALR1, OPN1MW, GDI1, GDI2, GFRA1, B4GALT1, GMDS, GNA15, GNAQ, GNAT2, GNGT2, GNRH2, GPR1, GPR3, GPR4, GPR15, GPR19, LPAR4, GPR26, FFAR1, GRB7, GRIA1, GRIA4, GRID1, GRID2, GRPR, GTF2I, GUCY2C, HIP1, HIVEP2, HRC, HTR2C, IAPP, ICAM2, SP110, IGFBP3, IGFBP6, IHH, INHA, INPP1, ITGAD, ITGAM, ITGAV, CD82, KCNN4, KIF5A, KISS1, KLRC3, LIMK1, LLGL2, LRPAP1, MAL, MGAT3, PPP1R12A, PPP1R12B, NTF4, NTSR1, OMP, OR1F1, OR2C1, P2RX1, P2RX3, PDE8A, PDYN, PIK3C2B, PI4KA, PLN, PPP2R1B, PRKCSH, PTGER1, PTH2R, PTPRJ, PTPRR, RAB1A, RAB3B, RAB4A, RAB5A, RAB5B, RAB6A, RAB27A, RABIF, RAC3, RANBP1, RAP2B, RBP1, RBP2, OPN1LW, PRPH2, DPF2, RFNG, RGR, RGS10, RGS12, RGS13, RPS27, CLIP1, RSU1, S100A1, S100A4, S100A11, S100A13, SALL1, TSPAN31, SCTR, SDC4, SEC14L1, SELE, SELP, SEMA3F, SFRP5, SH3BGR, SH3BGRL, SH3BP2, SHB, STIL, SIX3, SLC20A1, SOX10, SPINK1, SPOCK1, SRPK2, STRN, STYX, TACR3, CNTN2, TBL1X, DYNLT1, TSPAN7, TRHR, TRIP6, TRPC3, TSG101, TTK, TUFT1, TULP3, TYRO3, TYROBP, UPK1B, SCGB1A1, KDM6A, VDAC2, VIM, VIP, VIPR2, LAT2, YWHAZ, ZIC1, ZNF217, SEMA3B, ANP32A, RND2, MADCAM1, CLTCL1, FZD6, FZD9, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, OR1A1, OR1D5, OR1G1, OR3A3, SPARCL1, BCAR3, SORBS2, CNTNAP1, IKBKAP, UNC5C, SSNA1, PTCH2, NUMB, PDE5A, DYNLL1, S1PR4, CTNNAL1, HRK, TNFSF10, TNFSF9, ADAM15, DLK1, PEX11A, INPP4B, WISP3, EIF2B2, AP1M1, AP3D1, HIST1H3F, CDKL2, TAAR5, DOK2, ANGPTL1, DIRAS3, UNC119, USP8, DGKI, RASSF9, ZW10, REPS2, STK17B, STK17A, BCL7B, TAAR2, GPR55, TRIP10, RAB9A, SLC9A3R1, NRXN3, NRXN2, GRAP2, ARHGAP29, GTPBP1, GABBR2, CDC42BPB, AKAP12, RAB36, RIN1, AATK, GNA14, RALGPS1, ZNF516, SDC3, RIMS2, SEMA3E, IFT140, ARHGAP32, SNX17, CKAP5, SPOCK2, KIAA0141, GAB2, TRIL, RHOBTB1, P2RY14, ARHGAP25, ZBTB33, FRAT1, RANBP9, ABCC9, PDCD7, ARPC5, ARPC1B, ACTR2, ARPC2, SGK2, ARL4A, ARFRP1, G3BP1, ABI2, ATP6AP2, FARP1, WASF2, RNF41, RCAN2, STAM2 |
1615 | GO:0006996 | 0.00 | 1.20 | 331.80 | 371 | 1431 | organelle organization | ABCA1, ABL2, ACTB, ACTN1, ADD1, ABCD1, ANG, ANXA5, ARCN1, ARHGAP4, ARHGAP6, ARHGDIB, ARL1, RERE, ATP2A1, ATP2B2, BCL2A1, BCL2L1, BCR, BICD1, BLK, BMI1, BNIP3L, DST, BST2, TSPO, CAMK2A, CAPG, CAPN6, CASQ1, CASQ2, CD59, CDK4, CENPA, CHD2, CHD4, CIRBP, AP2S1, CLCN3, CLU, TPP1, CLN5, CNN1, CNN2, CNN3, CNP, COPA, COX8A, CREB1, CSF1R, CSNK1D, CTNNA1, CXADR, DDX1, DDX6, DIAPH1, DIAPH2, DNM1, DYNC1H1, DNM2, DPYSL3, TYMP, S1PR1, EFNA5, EML1, EMP2, EP300, EPB41, EPB41L2, EPHA5, EPS15, EYA4, ERCC3, ETS1, EYA2, EZH1, F2R, FANCF, FANCG, FEN1, FGD1, FGF7, CENPI, GAA, GABRA5, GAPDH, GFAP, GFER, GHSR, GOLGB1, GPX1, GRB7, GRIA1, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1T, HIST1H2AD, HIST1H1A, HARS, HEXB, HHEX, HIP1, HLCS, HMGN1, HMGA1, FOXA2, ONECUT1, HNRNPC, HRG, HSF4, HSPA4, HSPA9, IDUA, ILK, INPPL1, INSIG1, INSRR, ITGB1, JUN, KCNK3, KISS1, KIT, KRT9, KRT13, LLGL2, ATXN3, MYO1B, NUBP1, NTHL1, NUP98, P2RX5, PALM, PAM, PAX3, PCM1, PCNA, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PHF2, PPID, PPP2CB, PPP2R2A, PPP6C, PRIM2, PRKAA1, PRKAG1, PRKAR2B, PRKCI, PTK2, PTPRN, PURA, ABCD3, PEX5, RAB1A, RAB5B, RAB27A, RAC3, RAD23B, RAF1, RAG1, RAG2, RALA, RANBP2, RAP2A, RBL2, UPF1, REST, RFC3, RFC4, RFC5, RFX3, RLF, RPGR, RPA2, RPA3, RPL3, RPL3L, RPL5, RPL10, RPL38, RPS19, RPS27, SORT1, S100A8, S100A9, SALL1, SATB1, TRAPPC2, SET, SETMAR, SGK1, SHC1, STIL, SIPA1, SKP1, SLC9A1, SLCO1A2, SLC22A3, SMARCA1, SMARCA2, SMARCD3, SMARCE1, SNAP25, SNCA, SNRPD1, SNRPF, SOD2, SOX9, SP100, SPAG4, SRF, SRPK2, STAT2, STAT3, SUPV3L1, SYP, SYT4, TACC1, TAF7, TAF10, CNTN2, TAZ, TBCD, TBCE, TBL1X, TBP, TOP1, NR2C2, HSP90B1, TSC1, TSPY1, TTF1, TUBA4A, TUBG1, TUFM, SUMO1, CLRN1, KDM6A, UTY, UVRAG, VIM, WRB, XRCC5, YY1, ZNF189, PRDM2, TUBA1A, AAAS, GAN, CHAF1B, KDM5C, DYSF, HIST1H4I, PICALM, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H2BL, HIST1H2BN, HIST1H2BM, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, UXT, EEA1, CUL4A, SMARCA5, SORBS2, CNTNAP1, IKBKAP, HAT1, GAS7, COPS3, AP3B1, BLZF1, USO1, TP63, SSNA1, VAMP8, STX11, SAP30, ARHGEF7, AP1M1, AP3D1, HIST1H3F, HIST1H2AG, TAF1B, TAF1A, BAZ1B, USP8, ATP6V0D1, SEC22C, ZMYM6, VAPB, PDLIM7, COPB2, COPS2, TRIP11, TRIP10, HMGN3, GTF3C4, SNAP29, SLIT2, RAB33A, SLC9A3R1, NRXN1, NRXN2, COG1, PEX16, EIF2AK3, CHST3, ONECUT2, TBPL1, GOSR1, BAG5, SEC22B, CHD1L, BCAR1, GOSR2, CLOCK, CDC42BPB, NUP155, FEZ2, CEP135, KDM4A, NUP93, KIAA0391, CROCC, SEMA3E, SETD1A, IFT140, SLK, ZFYVE16, PHYHIP, TOMM20, RB1CC1, ARHGEF11, GINS1, ZEB2, CEP350, SNAP91, GOLGA5, USP3, NR1H4, RBX1, FGFBP1, HDAC6, RANBP9, COL4A3BP, KIF20A, AKAP9, G3BP1, WASF2, SPRY1, STAM2, ABCC4, ZMPSTE24 |
1616 | GO:0044267 | 0.01 | 1.19 | 312.59 | 348 | 1427 | cellular protein metabolic process | ABCA1, ABCA3, ABO, ACP1, ACTB, ACTL6A, ADAM10, ADD1, ADH5, ANXA1, KLK3, ARCN1, TRIM23, ARNTL, ARSA, STS, ARSD, ARSE, ARSF, ART1, ASL, ATR, AXL, BACH1, BARD1, BCHE, OPN1SW, BCR, BHMT, BLK, BNIP3L, BRCA2, BTK, CANX, CBL, CBLB, CCNF, CDK11B, CDK3, CDK6, CDK8, CHRM1, CHRM3, CHUK, TBCB, CLK1, CLK3, TPP1, COPA, CREB1, CSNK1G3, CTH, CTSK, DAD1, DMBT1, DYNC1H1, E4F1, PHC2, EEF1B2, EGR2, EIF1AX, ELK1, EPHA5, EPHB2, EPHB3, EYA4, ERCC3, ERG, EVPL, EXT2, EXTL1, EXTL3, EYA2, EZH1, FANCF, FAP, FAU, EFEMP1, FKBP3, FKBP5, FSHB, FUT6, FUT8, FYB, GAD1, GATA6, OPN1MW, GFER, B4GALT1, GMDS, GOLGB1, GRIA1, GUCY2C, GUCY2F, GUCY2D, HARS, HDGF, HEXB, HLCS, HMBS, HNRNPC, HSF4, HSPA9, IAPP, IGFBP6, IL12RB2, INSRR, ITGAV, KCNH2, LIPE, SMAD9, MAN2B1, MDH2, MGAT2, MGAT3, ATXN3, CNOT4, NUP98, OXTR, P4HA1, PAH, PAM, PCBP2, PCK1, PCNA, PDK4, PEX12, CFP, PFDN2, PHF2, PHKA2, PHKB, PHKG1, PPIB, PPID, PPM1B, PPP2CB, PPP4C, PPP6C, PRKCI, PRKCQ, PRKCSH, PRKX, PSKH1, PTPN4, PTPN7, PTPRE, PTPRH, PTPRN, PTPRN2, PTPRS, RAB1A, RAB3B, RAB6A, RAB27A, RABGGTA, RABGGTB, RAD21, RAG2, RANBP2, RANGAP1, RBBP6, OPN1LW, RGR, RNF6, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL24, RPL31, RPL34, RPL35A, RPL36AL, RPL37, RPL37A, RPL39, RPL36A, RPS3A, RPS4Y1, RPS6, RPS11, RPS19, RPS20, RPS27, SALL1, SATB1, SBF1, TRAPPC2, SETMAR, SFPQ, SFTPB, SFTPD, SGK1, SHMT2, SLC34A1, SOX11, SP100, UAP1, SPRR2A, SPRR2D, SPRR2E, SPRR2G, SPRR3, SRP14, SRPK2, STAT4, SULT1A3, TAF10, TBCD, TBCE, TBL1X, TOP1, TOP2A, TOP2B, NR2C2, TTC3, TTF1, TUBA4A, TUFM, TYRO3, UBA7, UBE2D2, UBE2E2, UBE2H, UCP1, KDM6A, UTY, VBP1, VRK1, TRIM25, ZBTB17, PRDM2, RNF103, TUBA1A, SCG2, TUSC3, NUP214, SLC25A16, AAAS, GAN, CLPP, USP11, USP9X, KDM5C, SMC1A, USP9Y, HIST1H4I, BAP1, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, DYRK2, CUL4A, CUL2, TPST2, TPST1, FKBP6, PPM1D, HAT1, COPS3, STK16, SLC25A12, RUVBL1, USO1, DDX3Y, DYNLL1, GALNT4, B4GALT4, B4GALT3, B3GALT2, CTSF, RIOK3, DYRK4, CDKL1, DPM2, EIF2S2, HERC2, HIST1H3F, P4HA2, CDKL2, RNF8, BAZ1B, UBA3, RPL14, USP2, USP8, ATP6V0D1, SMC3, DYRK1B, CTDP1, AURKB, STK17B, STK17A, COPB2, COPS2, GTF3C4, B4GALT6, RPL23, UBE4A, COG1, PICK1, PIGL, GOSR1, SEC22B, GTPBP1, GOSR2, CLOCK, CDC42BPB, RNF7, AATK, SNCAIP, NUP155, TTLL4, NUP93, UBE3C, SETD1A, TATDN2, TOMM20, SPOCK2, CUL7, DNAJC6, KLHL21, RNF10, USP3, NR1H4, PDCD6IP, GNE, PIGK, SH2D3C, SH2D3A, UBA2, SAE1, COL4A3BP, SGK2, ABI2, CHST4, SLC25A13, SLC25A15, ZMPSTE24 |
1617 | GO:0009889 | 0.01 | 1.18 | 290.88 | 323 | 1302 | regulation of biosynthetic process | ABCA2, ABL1, ACTL6A, ACTN1, ACVR2B, ADAR, AEBP1, NR0B1, ALX3, ANG, XIAP, BIRC5, ASCL2, ATP1A1, PRDM1, BMI1, BMP1, BMP8B, ZFP36L2, KLF9, BTF3, C3, CACNA1A, CBL, CD36, CDK11B, CDKN1A, CENPB, CENPF, CHD2, CHD4, CRY2, CSNK2A1, CSNK2A2, CTNND2, DAPK3, DDX1, DDX6, DHCR7, DHFR, DNMT1, DNMT3B, RCAN1, TSC22D3, DUSP1, E2F6, E4F1, ECM1, LPAR1, EFNA1, EGR3, EGR4, EIF2B1, EIF4A1, EIF4E, EIF4G2, EIF5, ELAVL2, EMX1, EMX2, EPRS, EYA4, ERF, ERG, ETV3, EWSR1, EYA2, FBN1, EFEMP1, FGFR3, GAPDH, GDF9, GHSR, GPC3, FFAR3, GRB7, GSC2, GTF2I, GTF3A, BRF1, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, HBE1, HDGF, HIC1, HIP1, HIVEP2, HLF, HMX2, HNRNPC, HOXC10, HOXD12, IDH1, SP110, INHA, EIF3E, ITGAV, JARID2, KCNK2, CAPRIN1, SMAD6, MAZ, ATXN3, TONSL, CNOT2, NTRK3, ORC1, ORC2, OVOL1, PA2G4, PALM, PAM, CHMP1A, PDE8A, PDK4, PIM1, PPID, PPP1R8, PPP2R1A, PRG2, PRKAR1A, PURA, RANBP2, RBBP6, RBL2, RBM4, UPF1, DPF2, RFX1, RPL38, RRM2, RYR2, S100A1, S100A11, SATB1, XCL1, TRAPPC2, SET, SFPQ, SFRP5, SFSWAP, SFTPD, SGK1, SIM2, SMARCE1, SNAPC3, SOD2, SOX3, SPIB, SRP9, STAT2, TAF4B, TAF10, ZNF354A, KLF10, TMPO, NR2C1, TRIP6, TSC1, TSG101, TTF1, TULP3, TNFSF4, TYMS, UBE2D2, UBE2L3, SUMO1, UCP1, SCGB1A1, VAV1, EIF4H, XRCC5, ZFP37, ZFPL1, ZNF3, ZNF7, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF35, ZKSCAN1, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF91, ZNF99, ZNF124, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, PRDM2, PDHX, ANP32A, ZNF239, DPF1, CHAF1B, USP9X, KDM5C, SMC1A, USP9Y, HIST1H4I, FZD6, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, CUL3, CUL2, KLF11, SMARCA5, IKBKAP, HAT1, GAS7, PIR, BLZF1, KHSRP, RGS20, RUVBL1, EIF4EBP3, AKR1C3, CHRD, DYNLL1, EIF3G, EIF4G3, EED, SAP30, HESX1, PER3, TAX1BP1, EIF2B3, EIF2B2, HIST1H3F, HIST1H2AG, TAF1B, TAF1A, RNF8, UBA3, USP2, PDLIM1, SMC3, ZNF235, COPS2, TRIP11, RECQL5, ZRANB2, ZNF264, AKAP6, LITAF, TBPL1, TMEM59, ZNF254, GABBR2, SOX13, RBM39, EIF5B, KDM4A, VGLL4, BZW1, RAPGEF2, ST18, ZNF646, SETD1A, ZFYVE16, RB1CC1, ZBTB24, ZNF518A, ZBTB5, RBM8A, RBX1, DMTF1, CASP8AP2, ZBTB33, ZNF263, ZNF256, EIF1, OLIG2, PRG4, DENND4A, IRX5, RAMP3 |
1618 | GO:0044260 | 0.03 | 1.14 | 370.37 | 399 | 1742 | cellular macromolecule metabolic process | ABCA2, ACTN1, AEBP1, NR0B1, ALX3, ANXA3, ARF1, PHOX2A, ASCL1, ASCL2, RERE, ATRX, BICD1, PRDM1, BRDT, KLF9, KLF5, BTF3, BYSL, CAPN1, RUNX2, CD3D, CD9, CD86, TNFSF8, CD63, CDH1, CDX2, CEBPE, CENPB, CHD2, CHD4, CLNS1A, COL1A1, COL11A1, COX6A1, COX6B1, COX7C, COX8A, CPS1, CRX, VCAN, CSTF3, CTNND2, DDX5, DDX10, DHFR, DKC1, DLX5, DNM1, DNM2, DNTT, DRD3, ARID3A, RCAN1, TSC22D3, E2F6, EBF1, TYMP, EDA, S1PR1, EGR3, EGR4, ELAVL2, EMX1, EMX2, EN1, ERCC4, ERF, ESRRG, ETS1, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, FANCE, FANCB, FANCG, FBN1, GPC4, AFF2, NR5A2, FZD2, G6PC, GAA, GALR1, GATA4, GCGR, GNAS, GPX2, GSC2, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, GYS2, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H2AD, HBE1, HEXA, HIC1, HIVEP2, HLF, HMGN1, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD8, HOXD9, HOXD10, HOXD12, IDS, IDUA, SP110, RBPJ, IHH, ING2, INSIG1, IRF1, IRF5, JUND, KCNK2, KPNA2, LCAT, LIPC, LMO1, MAZ, MEOX2, MGMT, CIITA, AFF1, FOXO4, DRG1, TONSL, YBX1, NTHL1, NVL, OAS3, ORC1, ORC2, ORC4, OTX1, OTX2, OVOL1, PAX3, PAX9, CHMP1A, PDE8A, PGR, PRIM2, PTGIS, PTMA, PTMS, PYGB, PYGM, RAB5A, RAD51C, RAD51B, RAD51D, RAN, RARB, RBL2, RBMS1, RBMS2, DPF2, REV3L, RFC3, RFC4, RFC5, RFX1, RFX3, RFXAP, RGS12, RHEB, RLF, RNASE1, RP9, RPA2, RPA3, RRM1, RRM2, RXRG, RYR2, S100A1, S100A11, SELE, SFRP5, SRSF1, SRSF5, SRSF7, SFSWAP, SIM2, SIX3, SLC9A1, SMARCA1, SMARCA2, SMARCA4, SMARCD3, SMARCE1, SNAI1, SNAPC3, SNRPA1, SNRPC, SNRPD1, SNRPE, SNRPF, SOD2, SOX3, SOX10, SP1, SPIB, SRF, SRY, SSRP1, STAT2, STAT3, STAT5B, STAT6, TAF4B, TAL1, TBP, HNF1A, ZNF354A, NR2F1, KLF10, TMPO, TNNI2, NR2C1, TRAF1, TRIP6, TSN, TULP3, TNFSF4, TYMS, SCGB1A1, UNG, USF1, VAV1, XPA, XRCC2, XRCC5, YY1, YWHAZ, ZFP37, ZFPL1, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF91, ZNF99, ZNF124, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, ZNF148, ZNF154, ZNF155, ZNF157, VEZF1, ZNF174, ZNF177, ZNF180, ZNF189, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZXDA, FOSL1, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, RBM10, FZD6, HIST1H2AK, HIST2H2AC, SOX14, UXT, ZNF282, KLF11, SMARCA5, PARG, GAS7, PIR, BLZF1, RRP1, RGS20, KLF7, TP63, CHRD, SRSF9, SAP30, HESX1, ALKBH1, PER3, TAX1BP1, BUD31, PHOX2B, MBD4, HIST1H2AG, MGAM, TAF1B, TAF1A, PDLIM1, PRPF3, CBFA2T2, EXO1, SCAF11, DDX21, CCPG1, ZNF235, TRIP11, HMGN3, GTF3C5, GTF3C3, EFTUD2, RECQL5, ZRANB2, SNRNP40, DDX23, HAND1, ZNF264, FHL5, IL27RA, CHST3, ONECUT2, LITAF, TBPL1, ZNF254, CHD1L, SOX13, RBM39, ZNF516, SDC3, VGLL4, BZW1, KIAA0391, ST18, ZNF646, ZFYVE16, ARHGEF11, GINS1, ZBTB24, ZNF518A, EPM2AIP1, ZBTB5, DCLRE1A, HS3ST3B1, NR1I3, NR1D2, REC8, DMTF1, NR2E3, ZBTB33, PDCD7, ZNF263, SUGP2, ZNF256, OLIG2, DENND4A, IRX5, RAMP3 |