| GOBPID | Pvalue | OddsRatio | ExpCount | Count | Size | Term | Genes |
1 | GO:0051482 | 0.00 | Inf | 2.34 | 8 | 8 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | AGTR1, S1PR1, LPAR1, EDNRA, F2R, GRM1, HTR2C, KISS1 |
2 | GO:0030194 | 0.00 | Inf | 2.05 | 7 | 7 | positive regulation of blood coagulation | CD36, F2R, F3, F7, F12, S100A9, SELP |
3 | GO:0007158 | 0.00 | Inf | 1.76 | 6 | 6 | neuron cell-cell adhesion | ASTN1, RET, TNR, NRXN3, NRXN1, NRXN2 |
4 | GO:0018119 | 0.00 | Inf | 1.76 | 6 | 6 | peptidyl-cysteine S-nitrosylation | ADH5, ACE, GAPDH, S100A8, S100A9, SNTA1 |
5 | GO:0044144 | 0.00 | Inf | 1.76 | 6 | 6 | modulation of growth of symbiont involved in interaction with host | CD36, CTSG, IFNG, IL10, IL12B, OSBP |
6 | GO:0051481 | 0.00 | Inf | 1.76 | 6 | 6 | negative regulation of cytosolic calcium ion concentration | ATP1A2, GTF2I, HRC, KCNA5, KCNK3, SLC8A1 |
7 | GO:0060158 | 0.00 | Inf | 1.76 | 6 | 6 | phospholipase C-activating dopamine receptor signaling pathway | DRD5, GNA15, GNAQ, GPR52, SLC9A3R1, GNA14 |
8 | GO:0090009 | 0.00 | Inf | 1.76 | 6 | 6 | primitive streak formation | ETS2, HHEX, FOXA2, OTX2, SRF, T |
9 | GO:0071241 | 0.00 | Inf | 1.45 | 5 | 5 | cellular response to inorganic substance | ATRX, BAD, RAD51, TNFSF4, EIF4A3 |
10 | GO:0009629 | 0.00 | Inf | 1.46 | 5 | 5 | response to gravity | BGLAP, CBLB, PTAFR, SPARC, FOSL1 |
11 | GO:0010642 | 0.00 | Inf | 1.46 | 5 | 5 | negative regulation of platelet-derived growth factor receptor signaling pathway | PTPN2, PTPRJ, SNCA, SLC9A3R1, PHF14 |
12 | GO:0010763 | 0.00 | Inf | 1.46 | 5 | 5 | positive regulation of fibroblast migration | DDR2, PRKCE, SLC8A1, ARHGEF7, BAG4 |
13 | GO:0019373 | 0.00 | Inf | 1.46 | 5 | 5 | epoxygenase P450 pathway | CYP1A2, CYP2A6, CYP2A13, CYP2F1, CYP4F2 |
14 | GO:0021542 | 0.00 | Inf | 1.46 | 5 | 5 | dentate gyrus development | CDK6, EMX2, PROX1, PTEN, NR2E1 |
15 | GO:0021796 | 0.00 | Inf | 1.46 | 5 | 5 | cerebral cortex regionalization | EMX1, EMX2, TRA2B, NR2F1, EOMES |
16 | GO:0042148 | 0.00 | Inf | 1.46 | 5 | 5 | strand invasion | RAD51, RAD51C, RAD51B, RAD51D, XRCC2 |
17 | GO:0043353 | 0.00 | Inf | 1.46 | 5 | 5 | enucleate erythrocyte differentiation | CEBPG, ID2, RB1, SP1, SP3 |
18 | GO:0044130 | 0.00 | Inf | 1.46 | 5 | 5 | negative regulation of growth of symbiont in host | CD36, CTSG, IFNG, IL10, IL12B |
19 | GO:0046629 | 0.00 | Inf | 1.46 | 5 | 5 | gamma-delta T cell activation | CXADR, EGR3, STAT5B, SYK, SOX13 |
20 | GO:0051918 | 0.00 | Inf | 1.46 | 5 | 5 | negative regulation of fibrinolysis | APOH, F2, HRG, SERPINE1, USF1 |
21 | GO:0070459 | 0.00 | Inf | 1.46 | 5 | 5 | prolactin secretion | ABAT, ANXA1, ANXA5, TACR2, VIP |
22 | GO:0071679 | 0.00 | Inf | 1.46 | 5 | 5 | commissural neuron axon guidance | EPHB2, RYK, VEGFA, FZD3, NRP1 |
23 | GO:0090192 | 0.00 | Inf | 1.46 | 5 | 5 | regulation of glomerulus development | AGTR2, BMP4, PAX2, RET, SERPINB7 |
24 | GO:2000074 | 0.00 | Inf | 1.46 | 5 | 5 | regulation of type B pancreatic cell development | ARNTL, BAD, RFX3, RHEB, CLOCK |
25 | GO:0097296 | 0.00 | 24.26 | 3.22 | 10 | 11 | activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | BAX, CASP8, CD14, SMAD3, TRAF2, TRADD, RIPK1, TNFSF10, TNFRSF10B, TNFRSF10A |
26 | GO:0006297 | 0.00 | 21.82 | 2.93 | 9 | 10 | nucleotide-excision repair, DNA gap filling | PCNA, RFC1, RFC3, RFC4, RFC5, RPA2, RPA3, RPS27A, UBB |
27 | GO:0030879 | 0.00 | 19.61 | 2.61 | 8 | 9 | mammary gland development | ARHGAP5, NRG1, HOXD9, IGF1, IGF1R, ITGA2, SOX9, BCL2L11 |
28 | GO:0010524 | 0.00 | 19.49 | 2.62 | 8 | 9 | positive regulation of calcium ion transport into cytosol | ADCYAP1R1, BMP4, CD4, P2RX3, P2RX4, P2RX5, P2RX7, TRPC3 |
29 | GO:0042511 | 0.00 | 19.39 | 2.63 | 8 | 9 | positive regulation of tyrosine phosphorylation of Stat1 protein | CD40, FGFR3, HPX, IFNG, KIT, TNFRSF1A, TNFRSF18, TNFSF18 |
30 | GO:0050880 | 0.00 | 17.15 | 2.32 | 7 | 8 | regulation of blood vessel size | ACTA2, DRD5, EDNRA, PIK3C2A, SLC6A4, SLC8A1, ITGB1BP1 |
31 | GO:0042417 | 0.00 | 16.99 | 2.34 | 7 | 8 | dopamine metabolic process | AGTR2, DAO, DBH, DRD3, GRIN2A, SNCB, SNCAIP |
32 | GO:0001774 | 0.00 | 16.96 | 2.34 | 7 | 8 | microglial cell activation | CLU, CX3CR1, IL13, JUN, CX3CL1, SNCA, TRPV1 |
33 | GO:0003085 | 0.00 | 16.96 | 2.34 | 7 | 8 | negative regulation of systemic arterial blood pressure | AGTR2, BBS4, BMPR2, NTSR1, PRCP, SOD2, KCNK6 |
34 | GO:0030238 | 0.00 | 16.96 | 2.34 | 7 | 8 | male sex determination | NR0B1, FGF9, IGF1R, INSRR, PTGDR, SOX9, SRY |
35 | GO:0036120 | 0.00 | 16.96 | 2.34 | 7 | 8 | cellular response to platelet-derived growth factor stimulus | CREB1, DNMT1, FYN, HAS1, HAS2, PTN, IQGAP1 |
36 | GO:0043312 | 0.00 | 16.96 | 2.34 | 7 | 8 | neutrophil degranulation | ANXA3, BCR, PTAFR, STXBP2, STXBP3, SYK, STX11 |
37 | GO:0048935 | 0.00 | 16.96 | 2.34 | 7 | 8 | peripheral nervous system neuron development | ETV1, HOXD9, HOXD10, ISL1, NTRK2, TBCE, ONECUT2 |
38 | GO:0055012 | 0.00 | 16.96 | 2.34 | 7 | 8 | ventricular cardiac muscle cell differentiation | CCNB1, NRG1, PROX1, RARA, RARB, RXRA, ATG5 |
39 | GO:0061440 | 0.00 | 16.96 | 2.34 | 7 | 8 | kidney vasculature development | ACTA2, ANGPT1, ANGPT2, AQP1, BMP4, SERPINB7, NRP1 |
40 | GO:0070365 | 0.00 | 16.96 | 2.34 | 7 | 8 | hepatocyte differentiation | ANXA1, BMP4, CPS1, HHEX, ITGA2, PROX1, WNT1 |
41 | GO:0030071 | 0.00 | 14.58 | 2.04 | 6 | 7 | regulation of mitotic metaphase/anaphase transition | CDC6, CENPE, PTEN, RB1, CUL3, DLGAP5 |
42 | GO:0001553 | 0.00 | 14.53 | 2.05 | 6 | 7 | luteinization | CAPN5, GDF9, PTPRN, STAT5B, FZD4, SGPL1 |
43 | GO:0002016 | 0.00 | 14.53 | 2.05 | 6 | 7 | regulation of blood volume by renin-angiotensin | AGTR1, AGTR2, CYBA, ACE, DRD3, RPS6KA2 |
44 | GO:0014819 | 0.00 | 14.53 | 2.05 | 6 | 7 | regulation of skeletal muscle contraction | ATP2A1, CASQ1, CAV3, KCNJ2, SLC8A3, GSTO1 |
45 | GO:0030916 | 0.00 | 14.53 | 2.05 | 6 | 7 | otic vesicle formation | FGF3, FGF8, PROX1, SOX9, HESX1, NRP1 |
46 | GO:0034616 | 0.00 | 14.53 | 2.05 | 6 | 7 | response to laminar fluid shear stress | ABCA1, ASS1, ETS1, SMAD6, SMAD7, KLF4 |
47 | GO:0043306 | 0.00 | 14.53 | 2.05 | 6 | 7 | positive regulation of mast cell degranulation | FCER1A, FGR, IL13, SYK, VAMP8, GAB2 |
48 | GO:0046112 | 0.00 | 14.53 | 2.05 | 6 | 7 | nucleobase biosynthetic process | ADA, APRT, CPS1, DHODH, HPRT1, SHMT1 |
49 | GO:0048563 | 0.00 | 14.53 | 2.05 | 6 | 7 | post-embryonic organ morphogenesis | BAX, FBN1, EFEMP1, HMGN1, KDR, BCL2L11 |
50 | GO:0050667 | 0.00 | 14.53 | 2.05 | 6 | 7 | homocysteine metabolic process | AHCY, BHMT, COMT, CPS1, CTH, DPEP1 |
51 | GO:0060020 | 0.00 | 14.53 | 2.05 | 6 | 7 | Bergmann glial cell differentiation | ABL1, ABL2, GFAP, MAPK1, MAPK3, VIM |
52 | GO:0061549 | 0.00 | 14.53 | 2.05 | 6 | 7 | sympathetic ganglion development | ASCL1, SEMA3F, FZD3, NRP2, NRP1, PHOX2B |
53 | GO:0071550 | 0.00 | 14.53 | 2.05 | 6 | 7 | death-inducing signaling complex assembly | CASP8, RAF1, TNFRSF1A, TRAF2, TRADD, RIPK1 |
54 | GO:0030155 | 0.00 | 13.89 | 3.70 | 11 | 13 | regulation of cell adhesion | S1PR1, ICAM1, LAMA3, LAMA4, PPP1R12A, SERPINI1, PPP2R1A, PRKX, SOX9, SRF, NUAK1 |
55 | GO:0001829 | 0.00 | 13.34 | 3.80 | 11 | 13 | trophectodermal cell differentiation | ADA, BYSL, CDX2, JUNB, CNOT2, SP1, SP3, SRF, EOMES, CUL3, HAND1 |
56 | GO:0007214 | 0.00 | 13.34 | 3.80 | 11 | 13 | gamma-aminobutyric acid signaling pathway | ATF4, CACNA1A, CACNB4, GABRA4, GABRA5, GABRB2, GABRE, GABRG1, GABRR1, GABRR2, GABBR2 |
57 | GO:0032735 | 0.00 | 13.34 | 3.80 | 11 | 13 | positive regulation of interleukin-12 production | CD36, CD40, IFNG, IL12B, IDO1, IRF1, IRF5, ISL1, TNFSF4, TNFSF9, RIPK2 |
58 | GO:0033627 | 0.01 | 12.17 | 1.75 | 5 | 6 | cell adhesion mediated by integrin | ICAM1, ITGA6, ITGA2, ADAM17, VTN |
59 | GO:0042220 | 0.00 | 12.17 | 5.26 | 15 | 18 | response to cocaine | BAX, CHRNB2, CNR1, CRH, CRHBP, DNM2, DNMT3A, DNMT3B, DRD5, PTK2B, HNMT, OXTR, SMPD1, TACR3, EFTUD2 |
60 | GO:1900407 | 0.01 | 12.16 | 1.75 | 5 | 6 | regulation of cellular response to oxidative stress | CD36, DHFR, FUT8, SNCA, RGN |
61 | GO:0010288 | 0.00 | 12.15 | 3.51 | 10 | 12 | response to lead ion | APP, CAT, CDK4, CPOX, DNMT3A, PPP5C, PTH, QDPR, SLC34A1, SPARC |
62 | GO:0035137 | 0.01 | 12.13 | 1.75 | 5 | 6 | hindlimb morphogenesis | BMPR1A, HOXD9, HOXD10, PTCH1, SALL1 |
63 | GO:0033189 | 0.00 | 12.13 | 3.51 | 10 | 12 | response to vitamin A | ARG1, CAT, DNMT1, DNMT3A, DNMT3B, GATA4, RARA, RXRA, SLC34A1, TYMS |
64 | GO:0042276 | 0.00 | 12.13 | 3.51 | 10 | 12 | error-prone translesion synthesis | PCNA, REV3L, RFC1, RFC3, RFC4, RFC5, RPA2, RPA3, RPS27A, UBB |
65 | GO:0070987 | 0.00 | 12.13 | 3.51 | 10 | 12 | error-free translesion synthesis | PCNA, RFC1, RFC3, RFC4, RFC5, RPA2, RPA3, RPS27A, UBB, UFD1L |
66 | GO:0009303 | 0.01 | 12.13 | 1.75 | 5 | 6 | rRNA transcription | ANG, GTF3A, BRF1, SMARCA4, TAF1B |
67 | GO:0006182 | 0.01 | 12.13 | 1.75 | 5 | 6 | cGMP biosynthetic process | AQP1, GUCY2C, GUCY2F, GUCY2D, HTR2C |
68 | GO:0050901 | 0.01 | 12.12 | 1.75 | 5 | 6 | leukocyte tethering or rolling | ITGB1, SELE, SELP, SELPLG, MADCAM1 |
69 | GO:0060561 | 0.01 | 12.12 | 1.75 | 5 | 6 | apoptotic process involved in morphogenesis | CRYAB, FGF4, PPP2R1B, FZD5, BCL2L11 |
70 | GO:0002551 | 0.01 | 12.11 | 1.76 | 5 | 6 | mast cell chemotaxis | KIT, RAC1, RAC2, VEGFA, VEGFB |
71 | GO:0003357 | 0.01 | 12.11 | 1.76 | 5 | 6 | noradrenergic neuron differentiation | PHOX2A, ASCL1, SOX4, SOX11, PHOX2B |
72 | GO:0006559 | 0.01 | 12.11 | 1.76 | 5 | 6 | L-phenylalanine catabolic process | GSTZ1, HPD, PAH, QDPR, TAT |
73 | GO:0006704 | 0.01 | 12.11 | 1.76 | 5 | 6 | glucocorticoid biosynthetic process | ATP1A1, CRH, CYP11B1, HSD11B1, REST |
74 | GO:0006782 | 0.01 | 12.11 | 1.76 | 5 | 6 | protoporphyrinogen IX biosynthetic process | ALAD, ALAS2, CPOX, HMBS, UROS |
75 | GO:0006853 | 0.01 | 12.11 | 1.76 | 5 | 6 | carnitine shuttle | ACACB, SLC25A20, CPT1B, CPT2, PRKAB2 |
76 | GO:0007263 | 0.01 | 12.11 | 1.76 | 5 | 6 | nitric oxide mediated signal transduction | AGTR2, CD36, FPR1, KCNC2, SPINK1 |
77 | GO:0014041 | 0.01 | 12.11 | 1.76 | 5 | 6 | regulation of neuron maturation | EDNRB, OPA1, RAC1, RAC3, RET |
78 | GO:0022010 | 0.01 | 12.11 | 1.76 | 5 | 6 | central nervous system myelination | CLU, FGFR3, KCNJ10, PTEN, CNTN2 |
79 | GO:0031284 | 0.01 | 12.11 | 1.76 | 5 | 6 | positive regulation of guanylate cyclase activity | GUCA1A, GUCA2A, GUCA2B, RCVRN, GUCA1C |
80 | GO:0035234 | 0.01 | 12.11 | 1.76 | 5 | 6 | ectopic germ cell programmed cell death | BAX, CASP5, IL1A, KIT, KITLG |
81 | GO:0035641 | 0.01 | 12.11 | 1.76 | 5 | 6 | locomotory exploration behavior | CRH, DPP4, PENK, PRKCE, TNR |
82 | GO:0042791 | 0.01 | 12.11 | 1.76 | 5 | 6 | 5S class rRNA transcription from RNA polymerase III type 1 promoter | GTF3C1, GTF3C2, GTF3C5, GTF3C4, GTF3C3 |
83 | GO:0042797 | 0.01 | 12.11 | 1.76 | 5 | 6 | tRNA transcription from RNA polymerase III promoter | GTF3C1, GTF3C2, GTF3C5, GTF3C4, GTF3C3 |
84 | GO:0046719 | 0.01 | 12.11 | 1.76 | 5 | 6 | regulation by virus of viral protein levels in host cell | DDB1, IFIT1, STAU1, DYNLT1, VAPB |
85 | GO:0046826 | 0.01 | 12.11 | 1.76 | 5 | 6 | negative regulation of protein export from nucleus | BARD1, CDK5, RANGAP1, SOX4, SP100 |
86 | GO:0048148 | 0.01 | 12.11 | 1.76 | 5 | 6 | behavioral response to cocaine | ABAT, ADRA1B, CDK5, DRD3, SNCA |
87 | GO:0048541 | 0.01 | 12.11 | 1.76 | 5 | 6 | Peyer's patch development | ADA, CACNB4, ID2, RET, STAT5B |
88 | GO:0048570 | 0.01 | 12.11 | 1.76 | 5 | 6 | notochord morphogenesis | EFNA1, EPHA2, T, KDM6A, WNT11 |
89 | GO:0060836 | 0.01 | 12.11 | 1.76 | 5 | 6 | lymphatic endothelial cell differentiation | ACVR2B, ACVRL1, BMPR2, PROX1, NR2F2 |
90 | GO:0070886 | 0.01 | 12.11 | 1.76 | 5 | 6 | positive regulation of calcineurin-NFAT signaling cascade | NRG1, IGF1, SLC9A1, SLC12A1, AKAP6 |
91 | GO:0086013 | 0.01 | 12.11 | 1.76 | 5 | 6 | membrane repolarization during cardiac muscle cell action potential | ATP1A1, KCNA5, KCNH2, KCNJ2, KCNQ1 |
92 | GO:1902221 | 0.01 | 12.11 | 1.76 | 5 | 6 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process | GSTZ1, HPD, PAH, QDPR, TAT |
93 | GO:2000727 | 0.01 | 12.11 | 1.76 | 5 | 6 | positive regulation of cardiac muscle cell differentiation | BMP4, EFNB2, NRG1, RBPJ, AKAP6 |
94 | GO:0033574 | 0.00 | 11.33 | 4.98 | 14 | 17 | response to testosterone | BAD, BGLAP, BMP4, TSPO, CDK4, DNMT1, DUSP1, ELK1, HMGCS2, KCNJ11, PLN, PSPH, RPS6KB1, SRD5A1 |
95 | GO:0072488 | 0.00 | 11.33 | 4.98 | 14 | 17 | ammonium transmembrane transport | ACACB, AQP1, SLC25A20, CPT1B, CPT2, PRKAB2, RHAG, RHCE, RHD, SLC12A2, SLC22A1, SLC22A3, SLC22A2, SLC22A5 |
96 | GO:0034767 | 0.00 | 11.25 | 8.17 | 23 | 28 | positive regulation of ion transmembrane transport | ABL1, ARF1, BAX, BDKRB1, CRH, DPP6, EDNRA, F2, F2R, GCG, IL13, KCNC2, KCNH2, KCNJ2, KCNQ1, P2RX7, PDPK1, XCL1, SLC34A1, SNCA, STC1, TRPC1, ZP3 |
97 | GO:0010002 | 0.00 | 10.91 | 3.22 | 9 | 11 | cardioblast differentiation | GATA4, GATA6, NRG1, RBPJ, ISL1, REST, SRF, T, EOMES |
98 | GO:0038084 | 0.00 | 10.52 | 4.68 | 13 | 16 | vascular endothelial growth factor signaling pathway | CD63, DCN, FLT1, FLT3, FLT4, HRG, HSPB1, KDR, PRKD1, VEGFA, NRP2, NRP1, ADAMTS3 |
99 | GO:0006335 | 0.00 | 10.33 | 6.15 | 17 | 21 | DNA replication-dependent nucleosome assembly | RBBP4, CHAF1B, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HAT1, HIST1H3F |
100 | GO:0043278 | 0.00 | 9.71 | 4.39 | 12 | 15 | response to morphine | ADA, ADRA1B, CNR1, DRD3, EDNRA, FGA, PENK, PPP2R2A, PPP5C, PRKCE, TACR3, PEA15 |
101 | GO:0001913 | 0.00 | 9.69 | 2.93 | 8 | 10 | T cell mediated cytotoxicity | CTSH, EMP2, IL12B, P2RX7, PVR, RAB27A, XCL1, STX11 |
102 | GO:0010248 | 0.00 | 9.69 | 2.93 | 8 | 10 | establishment or maintenance of transmembrane electrochemical gradient | ATP1A1, ATP1A2, ATP1A3, ATP12A, FXYD2, ATP4A, BAX, SLC22A1 |
103 | GO:0010954 | 0.00 | 9.69 | 2.93 | 8 | 10 | positive regulation of protein processing | ADAM8, C3, F12, HPN, KLKB1, PHB, CNTN2, CLEC3B |
104 | GO:0016558 | 0.00 | 9.69 | 2.93 | 8 | 10 | protein import into peroxisome matrix | PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX5, PEX16 |
105 | GO:0044849 | 0.00 | 9.69 | 2.93 | 8 | 10 | estrous cycle | ANXA1, CLU, ETS1, HAS1, HAS2, OXTR, PTN, TRPM2 |
106 | GO:0060421 | 0.00 | 9.69 | 2.93 | 8 | 10 | positive regulation of heart growth | ACACB, CCNB1, GATA4, GATA6, NRG1, RBPJ, PROX1, AKAP6 |
107 | GO:0071941 | 0.00 | 9.69 | 2.93 | 8 | 10 | nitrogen cycle metabolic process | ARG1, ARG2, ASL, ASS1, CPS1, SUOX, NR1H4, SLC25A15 |
108 | GO:0046697 | 0.00 | 8.89 | 4.10 | 11 | 14 | decidualization | BSG, CYP27B1, EPOR, GHSR, GJB2, JUNB, MEN1, PTGIS, PTGS2, STC1, VDR |
109 | GO:0050921 | 0.00 | 8.56 | 2.62 | 7 | 9 | positive regulation of chemotaxis | BMPR2, LPAR1, HSPB1, PRKD1, NRP1, SLIT2, PPM1F |
110 | GO:0001657 | 0.00 | 8.52 | 5.26 | 14 | 18 | ureteric bud development | ARG2, CAT, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, RARA, RARB, RET, SDC1, SDC4, SLIT2, SPRY1 |
111 | GO:0033762 | 0.00 | 8.52 | 2.62 | 7 | 9 | response to glucagon | CDO1, CREB1, CYC1, HMGCS2, QDPR, RPS6KB1, SREBF1 |
112 | GO:0001974 | 0.00 | 8.51 | 5.26 | 14 | 18 | blood vessel remodeling | ACVR2B, ACVRL1, ADRA1B, AGTR2, AXL, BAX, BMPR2, DBH, ACE, FGF8, IGF1, RBPJ, ITGA4, ATG5 |
113 | GO:0060416 | 0.00 | 8.51 | 2.63 | 7 | 9 | response to growth hormone | ASS1, CPS1, F7, HMGCS2, RBBP4, SLC34A1, SRD5A1 |
114 | GO:0002042 | 0.00 | 8.50 | 5.27 | 14 | 18 | cell migration involved in sprouting angiogenesis | EFNB2, EGR3, GPLD1, NR4A1, ITGB1, KDR, PTGS2, SRF, NR2E1, VEGFA, NRP1, ITGB1BP1, KLF4, SLIT2 |
115 | GO:0033280 | 0.00 | 8.50 | 2.63 | 7 | 9 | response to vitamin D | CD4, CDKN2D, PTH, PTGS2, RXRA, STC1, TYR |
116 | GO:0001502 | 0.00 | 8.48 | 2.63 | 7 | 9 | cartilage condensation | BMP1, COL2A1, COL11A1, CTGF, FGF4, FGF6, SOX9 |
117 | GO:0003301 | 0.00 | 8.48 | 2.63 | 7 | 9 | physiological cardiac muscle hypertrophy | AGTR2, CAV3, GATA4, COL14A1, SORBS2, CTDP1, AKAP6 |
118 | GO:0030207 | 0.00 | 8.48 | 2.63 | 7 | 9 | chondroitin sulfate catabolic process | VCAN, CSPG4, DCN, HEXA, HEXB, IDS, IDUA |
119 | GO:0035994 | 0.00 | 8.48 | 2.63 | 7 | 9 | response to muscle stretch | CAV3, CHUK, JUN, RAF1, RYR2, SLC8A1, SLC9A1 |
120 | GO:0043496 | 0.00 | 8.48 | 2.63 | 7 | 9 | regulation of protein homodimerization activity | BAX, NRG1, ISL1, ITGA4, TRAF2, TNFSF18, TRAF4 |
121 | GO:0045899 | 0.00 | 8.48 | 2.63 | 7 | 9 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly | AHR, CREB1, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5 |
122 | GO:0048532 | 0.00 | 8.48 | 2.63 | 7 | 9 | anatomical structure arrangement | BMPR1A, EGR2, PAX2, RAC1, SEMA3F, USP9X, NRP1 |
123 | GO:0051580 | 0.00 | 8.48 | 2.63 | 7 | 9 | regulation of neurotransmitter uptake | ATP1A2, DRD3, GDNF, GFAP, GPM6B, RAB3B, SNCA |
124 | GO:0070230 | 0.00 | 8.48 | 2.63 | 7 | 9 | positive regulation of lymphocyte apoptotic process | ADAM8, BAX, IL10, IDO1, P2RX7, SIGLEC1, PDCD7 |
125 | GO:0072176 | 0.00 | 8.48 | 2.63 | 7 | 9 | nephric duct development | BMP4, EFNB2, EPHA4, GATA3, GPC3, PAX2, WNT11 |
126 | GO:2001241 | 0.00 | 8.48 | 2.63 | 7 | 9 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | BAX, CTNNA1, DAPK3, PPP1CA, PPP2R1A, PPP2R1B, RET |
127 | GO:0038123 | 0.00 | 8.35 | 9.07 | 24 | 31 | toll-like receptor TLR1:TLR2 signaling pathway | BTK, CD14, CD36, CHUK, CREB1, DUSP7, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK1, MAPK3, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, UBB, UBE2V1, CUL1, IKBKG, RIPK2, RPS6KA5 |
128 | GO:0038124 | 0.00 | 8.35 | 9.07 | 24 | 31 | toll-like receptor TLR6:TLR2 signaling pathway | BTK, CD14, CD36, CHUK, CREB1, DUSP7, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK1, MAPK3, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, UBB, UBE2V1, CUL1, IKBKG, RIPK2, RPS6KA5 |
129 | GO:0038083 | 0.00 | 8.26 | 6.44 | 17 | 22 | peptidyl-tyrosine autophosphorylation | ABL1, ABL2, BLK, BMX, BTK, ACE, PTK2B, FGR, FYN, IGF1R, KDR, MAPK3, PTK2, SYK, TYK2, VEGFA, AATK |
130 | GO:0035666 | 0.00 | 8.23 | 10.24 | 27 | 35 | TRIF-dependent toll-like receptor signaling pathway | BIRC3, CASP8, CD14, CHUK, CREB1, DUSP7, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK1, MAPK3, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, UBB, UBE2D1, UBE2D2, CUL1, IKBKG, RIPK1, RIPK2, RPS6KA5, TANK |
131 | GO:0045987 | 0.00 | 8.09 | 3.80 | 10 | 13 | positive regulation of smooth muscle contraction | ADA, ADRA1B, CHRM3, CTTN, F2R, ITGA2, PTAFR, PTGS1, PTGS2, SRF |
132 | GO:0002068 | 0.00 | 8.08 | 3.80 | 10 | 13 | glandular epithelial cell development | ARNTL, BAD, BMP4, CDK6, PDPK1, RARA, RARB, RFX3, RHEB, CLOCK |
133 | GO:0003309 | 0.00 | 8.08 | 3.80 | 10 | 13 | type B pancreatic cell differentiation | ARNTL, BAD, BMP4, CDK6, GATA6, MEN1, PDPK1, RFX3, RHEB, CLOCK |
134 | GO:0032201 | 0.00 | 8.08 | 3.80 | 10 | 13 | telomere maintenance via semi-conservative replication | FEN1, PCNA, PRIM2, UPF1, RFC1, RFC3, RFC4, RFC5, RPA2, RPA3 |
135 | GO:0060397 | 0.00 | 8.08 | 3.80 | 10 | 13 | JAK-STAT cascade involved in growth hormone signaling pathway | CSH1, GH2, MAPK1, MAPK3, PRL, PTPN6, STAT3, STAT5B, ADAM17, SOCS3 |
136 | GO:0070306 | 0.00 | 8.08 | 3.80 | 10 | 13 | lens fiber cell differentiation | BFSP1, CRYGB, EPHA2, FGFR3, SMAD3, NTRK3, PROX1, SIX3, VIM, ZEB2 |
137 | GO:1900408 | 0.00 | 7.89 | 4.98 | 13 | 17 | negative regulation of cellular response to oxidative stress | ATF4, EPOR, GPX1, HGF, HP, HSPB1, INS, PSAP, PYCR1, SOD2, VNN1, BAG5, TRAP1 |
138 | GO:0002755 | 0.00 | 7.62 | 9.66 | 25 | 33 | MyD88-dependent toll-like receptor signaling pathway | BTK, CD14, CD36, CHUK, CREB1, DUSP7, ELK1, IRAK1, IRAK2, IRF1, JUN, PPP2R5D, MAPK1, MAPK3, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, UBB, UBE2V1, CUL1, IKBKG, RIPK2, RPS6KA5 |
139 | GO:0070542 | 0.00 | 7.32 | 3.50 | 9 | 12 | response to fatty acid | ALAD, BAD, CAT, CD36, CTGF, FFAR1, LIPC, PTGS1, PTGS2 |
140 | GO:0035107 | 0.00 | 7.31 | 3.50 | 9 | 12 | appendage morphogenesis | ATRX, COL2A1, IDUA, PCSK5, SOX4, SOX9, SOX11, ZNF141, IFT140 |
141 | GO:0034166 | 0.00 | 7.30 | 8.19 | 21 | 28 | toll-like receptor 10 signaling pathway | CHUK, CREB1, DUSP7, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK1, MAPK3, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, UBB, UBE2V1, CUL1, IKBKG, RIPK2, RPS6KA5 |
142 | GO:0002705 | 0.01 | 7.30 | 2.33 | 6 | 8 | positive regulation of leukocyte mediated immunity | FGR, IL13, PTAFR, SYK, VAMP8, GAB2 |
143 | GO:0050918 | 0.00 | 7.29 | 3.50 | 9 | 12 | positive chemotaxis | ANGPT1, ANGPT2, BMP4, FGF7, FGF8, HGF, PTPRJ, SAA4, NRP1 |
144 | GO:0051281 | 0.00 | 7.29 | 5.85 | 15 | 20 | positive regulation of release of sequestered calcium ion into cytosol | ABL1, BAX, BDKRB1, CALM3, EDNRA, F2, F2R, IL13, NTSR1, PDPK1, XCL1, SNCA, TRPC1, GSTO1, AKAP6 |
145 | GO:0071242 | 0.00 | 7.28 | 3.51 | 9 | 12 | cellular response to ammonium ion | ABL1, ASS1, CRH, CRHBP, DNM2, ID1, KCNC2, PTAFR, SLC34A1 |
146 | GO:0002891 | 0.00 | 7.28 | 4.68 | 12 | 16 | positive regulation of immunoglobulin mediated immune response | C3, CD28, CD40, FCER1A, FCER2, HPX, IFNG, XCL1, STAT6, TNFSF4, UNG, TNFSF13 |
147 | GO:0043574 | 0.01 | 7.27 | 2.34 | 6 | 8 | peroxisomal transport | PEX1, PEX6, PEX7, PEX10, PEX12, PEX13 |
148 | GO:0055119 | 0.01 | 7.27 | 2.34 | 6 | 8 | relaxation of cardiac muscle | ATP1A1, ATP1A2, KCNJ2, P2RX4, SLC8A1, PDE5A |
149 | GO:0002861 | 0.00 | 7.27 | 3.51 | 9 | 12 | regulation of inflammatory response to antigenic stimulus | C3, CD28, CNR1, FCER1A, GPX1, IL10, IL12B, PSMB4, ZP3 |
150 | GO:0008045 | 0.00 | 7.27 | 3.51 | 9 | 12 | motor neuron axon guidance | CDK5, CHN1, EGR2, EPHA4, ETV4, FGF8, SEMA3F, NRP1, SLIT2 |
151 | GO:0010592 | 0.00 | 7.27 | 3.51 | 9 | 12 | positive regulation of lamellipodium assembly | AQP1, DNM2, RAC1, RAC2, FSCN1, CLRN1, WNT1, ARPC2, WASF2 |
152 | GO:0035574 | 0.00 | 7.27 | 3.51 | 9 | 12 | histone H4-K20 demethylation | HIST1H4I, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L |
153 | GO:0060765 | 0.00 | 7.27 | 3.51 | 9 | 12 | regulation of androgen receptor signaling pathway | DDX5, EP300, IGF1, PHB, RNF6, SMARCA4, BUD31, RNF14, HDAC6 |
154 | GO:0072663 | 0.00 | 7.27 | 3.51 | 9 | 12 | establishment of protein localization to peroxisome | PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX19, PEX5, PEX16 |
155 | GO:0000050 | 0.01 | 7.27 | 2.34 | 6 | 8 | urea cycle | ARG1, ARG2, ASL, ASS1, CPS1, SLC25A15 |
156 | GO:0002664 | 0.01 | 7.27 | 2.34 | 6 | 8 | regulation of T cell tolerance induction | CBLB, CD3E, CD86, CLC, IL2RA, IDO1 |
157 | GO:0002830 | 0.01 | 7.27 | 2.34 | 6 | 8 | positive regulation of type 2 immune response | CD86, CD74, IDO1, RARA, XCL1, TNFSF4 |
158 | GO:0007494 | 0.01 | 7.27 | 2.34 | 6 | 8 | midgut development | ASS1, CPS1, EDNRB, HMGCS2, RET, RXRA |
159 | GO:0010310 | 0.01 | 7.27 | 2.34 | 6 | 8 | regulation of hydrogen peroxide metabolic process | HP, RAC1, RAC2, SNCA, STAT3, HDAC6 |
160 | GO:0015879 | 0.01 | 7.27 | 2.34 | 6 | 8 | carnitine transport | ACACB, SLC25A20, CPT1B, CPT2, PRKAB2, SLC22A5 |
161 | GO:0019371 | 0.01 | 7.27 | 2.34 | 6 | 8 | cyclooxygenase pathway | CBR1, HPGD, PTGIS, PTGS1, PTGS2, AKR1C3 |
162 | GO:0021794 | 0.01 | 7.27 | 2.34 | 6 | 8 | thalamus development | CHRNB2, OGDH, PTN, SLC6A4, SRD5A1, OLIG2 |
163 | GO:0030007 | 0.01 | 7.27 | 2.34 | 6 | 8 | cellular potassium ion homeostasis | ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP4A, KCNJ2 |
164 | GO:0031581 | 0.01 | 7.27 | 2.34 | 6 | 8 | hemidesmosome assembly | DST, CD151, ITGA6, KRT5, KRT14, LAMA3 |
165 | GO:0033005 | 0.01 | 7.27 | 2.34 | 6 | 8 | positive regulation of mast cell activation | FCER1A, FGR, IL13, SYK, VAMP8, GAB2 |
166 | GO:0036376 | 0.01 | 7.27 | 2.34 | 6 | 8 | sodium ion export from cell | ATP1A1, ATP1A2, ATP1A3, ATP12A, FXYD2, ATP4A |
167 | GO:0042523 | 0.01 | 7.27 | 2.34 | 6 | 8 | positive regulation of tyrosine phosphorylation of Stat5 protein | CSF2, FYN, IGF1, IL3, IL12B, KIT |
168 | GO:0042832 | 0.01 | 7.27 | 2.34 | 6 | 8 | defense response to protozoan | BCL3, CD37, CD40, IFNG, IL10, IL12B |
169 | GO:0043173 | 0.01 | 7.27 | 2.34 | 6 | 8 | nucleotide salvage | ADA, AMPD1, AMPD2, APRT, HPRT1, UPP1 |
170 | GO:0046541 | 0.01 | 7.27 | 2.34 | 6 | 8 | saliva secretion | AQP1, AQP5, CHRM1, CHRM3, KCNN4, TRPC1 |
171 | GO:0046689 | 0.01 | 7.27 | 2.34 | 6 | 8 | response to mercury ion | ALAD, ALB, AQP1, BSG, SLC34A1, TAT |
172 | GO:0051775 | 0.01 | 7.27 | 2.34 | 6 | 8 | response to redox state | ADH5, ARHGDIB, ARNTL, RYR2, CLOCK, RNF7 |
173 | GO:0055093 | 0.01 | 7.27 | 2.34 | 6 | 8 | response to hyperoxia | CAT, CDK4, CDKN1A, COL1A1, DNMT3B, KCNA5 |
174 | GO:0060405 | 0.01 | 7.27 | 2.34 | 6 | 8 | regulation of penile erection | ADA, CNR1, EDNRB, OXTR, P2RY2, VIP |
175 | GO:0060433 | 0.01 | 7.27 | 2.34 | 6 | 8 | bronchus development | BMP4, IL13, SOX9, SRF, TULP3, ADAMTSL2 |
176 | GO:0071243 | 0.01 | 7.27 | 2.34 | 6 | 8 | cellular response to arsenic-containing substance | ATF3, ATF4, DDX3X, HMBS, UROS, GSTO1 |
177 | GO:0090083 | 0.01 | 7.27 | 2.34 | 6 | 8 | regulation of inclusion body assembly | CLU, DNAJB2, PSMC5, SORL1, BAG5, SNCAIP |
178 | GO:0097421 | 0.01 | 7.27 | 2.34 | 6 | 8 | liver regeneration | FGA, KLKB1, PTPN3, RAP1A, SRSF5, RGN |
179 | GO:1903427 | 0.01 | 7.27 | 2.34 | 6 | 8 | negative regulation of reactive oxygen species biosynthetic process | TSPO, IL10, PTGIS, STAT3, RGN, TRAP1 |
180 | GO:2000811 | 0.01 | 7.27 | 2.34 | 6 | 8 | negative regulation of anoikis | BCL2L1, ITGA5, ITGB1, NTRK2, PDK4, PTK2 |
181 | GO:0021954 | 0.00 | 6.82 | 5.55 | 14 | 19 | central nervous system neuron development | ASCL1, CDK5, CHRNB2, DCC, EPHA4, EPHB1, EPHB3, HPRT1, NTRK2, PTEN, PTK2, NR2E1, PHOX2B, DCLK1 |
182 | GO:0097192 | 0.00 | 6.71 | 4.37 | 11 | 15 | extrinsic apoptotic signaling pathway in absence of ligand | BAD, BCL2A1, BOK, CASP9, DCC, EYA2, IGF1, ITGAV, KITLG, BAG3, BCL2L11 |
183 | GO:0051412 | 0.00 | 6.67 | 4.39 | 11 | 15 | response to corticosterone | ATP2B1, BAX, CALM3, CCNE1, CDKN1A, CRH, JUNB, NTRK3, PTGS1, TRH, FOSL1 |
184 | GO:0051436 | 0.00 | 6.60 | 10.81 | 27 | 37 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS27A, UBB, PSMF1, PSME3, PSMD14 |
185 | GO:0048661 | 0.00 | 6.60 | 7.61 | 19 | 26 | positive regulation of smooth muscle cell proliferation | BMP4, CYBA, S1PR1, FLT1, HMGCR, ID2, IGF1, IL13, IRAK1, ITGA2, JUN, ORC1, PTAFR, PTGS2, RPS6KB1, CX3CL1, SHC1, SKP2, STAT5B |
186 | GO:0002703 | 0.00 | 6.52 | 3.20 | 8 | 11 | regulation of leukocyte mediated immunity | BTK, CLC, IL10, PDPK1, RAC2, STXBP2, WAS, IL27RA |
187 | GO:0014013 | 0.00 | 6.50 | 3.21 | 8 | 11 | regulation of gliogenesis | CREB1, EMX1, ETV5, EFEMP1, GFAP, PRKCI, PTPRZ1, SOX10 |
188 | GO:0007595 | 0.00 | 6.48 | 6.44 | 16 | 22 | lactation | APRT, ATP2B2, CDO1, CHUK, CREB1, DHODH, SLC29A1, GHRHR, HK2, OXTR, PAM, PRL, STAT5B, VDR, VEGFA, EIF2AK3 |
189 | GO:1901216 | 0.00 | 6.48 | 3.21 | 8 | 11 | positive regulation of neuron death | ABL1, BAD, CLU, ELK1, PTPRZ1, TRPM2, AIMP2, PICALM |
190 | GO:0045844 | 0.00 | 6.47 | 3.22 | 8 | 11 | positive regulation of striated muscle tissue development | BMP4, CCNB1, EFNB2, GATA4, GATA6, NRG1, RBPJ, AKAP6 |
191 | GO:0010881 | 0.00 | 6.46 | 3.22 | 8 | 11 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion | ATP1A2, CALM3, CASQ2, HRC, PLN, RYR2, SLC8A1, GSTO1 |
192 | GO:0030949 | 0.00 | 6.46 | 3.22 | 8 | 11 | positive regulation of vascular endothelial growth factor receptor signaling pathway | ARNT, FGF9, FLT1, ITGA5, PRKCB, VEGFA, VEGFB, VTN |
193 | GO:0031646 | 0.00 | 6.46 | 3.22 | 8 | 11 | positive regulation of neurological system process | CHRNB4, HGF, NRG1, ITGA2, P2RX3, PTAFR, TNR, RNF10 |
194 | GO:0033141 | 0.00 | 6.46 | 3.22 | 8 | 11 | positive regulation of peptidyl-serine phosphorylation of STAT protein | IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, RET |
195 | GO:0060055 | 0.00 | 6.46 | 3.22 | 8 | 11 | angiogenesis involved in wound healing | ETS1, B4GALT1, GPX1, SERPINE1, PRCP, CX3CL1, SRF, VEGFB |
196 | GO:0060307 | 0.00 | 6.46 | 3.22 | 8 | 11 | regulation of ventricular cardiac muscle cell membrane repolarization | CAV3, KCNH2, KCNQ1, SCN4B, SCN5A, SNTA1, WDR1, AKAP9 |
197 | GO:0070242 | 0.00 | 6.46 | 3.22 | 8 | 11 | thymocyte apoptotic process | ADA, ADAM8, BAX, BMP4, CASP8, DFFA, RAG1, BCL2L11 |
198 | GO:0070293 | 0.00 | 6.46 | 3.22 | 8 | 11 | renal absorption | AQP1, HAS2, KCNJ1, KCNQ1, SGK1, HNF1A, AKR1C3, SLC9A3R1 |
199 | GO:0070498 | 0.00 | 6.46 | 3.22 | 8 | 11 | interleukin-1-mediated signaling pathway | IL1R1, IL1RN, IRAK1, IRAK2, MAPK3, IL1RL2, RPS6KA4, RPS6KA5 |
200 | GO:0098810 | 0.00 | 6.46 | 3.22 | 8 | 11 | neurotransmitter reuptake | ATP1A2, DRD3, GDNF, GPM6B, KCNJ10, RAB3B, SLC6A4, SNCA |
201 | GO:0034146 | 0.00 | 6.39 | 8.49 | 21 | 29 | toll-like receptor 5 signaling pathway | CHUK, CREB1, DUSP7, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK1, MAPK3, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, UBB, UBE2V1, CUL1, IKBKG, RIPK2, RPS6KA5 |
202 | GO:2000106 | 0.00 | 6.33 | 5.26 | 13 | 18 | regulation of leukocyte apoptotic process | ADAM8, ANXA1, BAX, BTK, CASP8, CD3G, IL10, P2RX7, PTEN, SIGLEC1, ADAM17, RAPGEF2, PDCD7 |
203 | GO:1901568 | 0.00 | 6.33 | 5.26 | 13 | 18 | fatty acid derivative metabolic process | ACOX1, ALOX15B, DAGLA, CYP1A2, CYP2A6, CYP2A13, CYP2F1, DPEP1, FAAH, GPX1, MAPK3, TNFRSF1A, CYP4F2 |
204 | GO:0060306 | 0.00 | 6.31 | 5.27 | 13 | 18 | regulation of membrane repolarization | CASQ2, CAV3, KCNA5, KCNH2, KCNJ2, KCNQ1, SCN4B, SCN5A, SNTA1, AKAP7, AKAP6, WDR1, AKAP9 |
205 | GO:0071312 | 0.00 | 6.31 | 5.27 | 13 | 18 | cellular response to alkaloid | BAD, BCL2L1, CASQ2, CRH, CRHBP, ICAM1, KCNJ11, RAD51, RYR1, RYR2, SLC8A1, SLC34A1, TRPV1 |
206 | GO:0070371 | 0.02 | 6.16 | 2.02 | 5 | 7 | ERK1 and ERK2 cascade | CTSH, ITGAV, OXTR, MAPK1, SOX9 |
207 | GO:0051047 | 0.00 | 6.15 | 4.06 | 10 | 14 | positive regulation of secretion | AQP1, CYBA, DRD3, EDNRB, KNG1, P2RX4, P2RY2, TRPV1, CYP4F2, ATG5 |
208 | GO:1903036 | 0.00 | 6.12 | 6.11 | 15 | 21 | positive regulation of response to wounding | ANXA1, APOH, CD36, F2, F2R, F3, F7, HRG, NTRK3, REG3A, PRKCE, SELP, USF1, VEGFB, VTN |
209 | GO:0022602 | 0.03 | 6.11 | 2.03 | 5 | 7 | ovulation cycle process | KISS1, PAM, PGR, NRIP1, SLIT2 |
210 | GO:0010518 | 0.03 | 6.10 | 2.04 | 5 | 7 | positive regulation of phospholipase activity | AGTR1, ARF4, ARL1, FGFR3, PDPK1 |
211 | GO:0014068 | 0.00 | 6.09 | 10.24 | 25 | 35 | positive regulation of phosphatidylinositol 3-kinase signaling | ANGPT1, CAT, CBL, CD28, DCN, F2, F2R, FGR, FLT1, FLT3, FSHR, FYN, HCLS1, HGF, NRG1, IGF1, INS, KDR, KIT, NTRK2, PTK2, PTPN6, SELP, SOX9, UBE3A |
212 | GO:0034134 | 0.00 | 6.09 | 10.24 | 25 | 35 | toll-like receptor 2 signaling pathway | BTK, CD14, CD36, CHUK, CREB1, CYBA, DUSP7, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK1, MAPK3, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, UBB, UBE2V1, CUL1, IKBKG, RIPK2, RPS6KA5 |
213 | GO:1903426 | 0.03 | 6.09 | 2.04 | 5 | 7 | regulation of reactive oxygen species biosynthetic process | CLCN3, CYBA, RAB27A, SNCA, OGT |
214 | GO:0032776 | 0.00 | 6.08 | 6.14 | 15 | 21 | DNA methylation on cytosine | H3F3B, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HIST1H3F |
215 | GO:0014075 | 0.03 | 6.08 | 2.04 | 5 | 7 | response to amine | ARG1, CPS1, HNMT, ITGA2, KCNC2 |
216 | GO:0050764 | 0.03 | 6.07 | 2.04 | 5 | 7 | regulation of phagocytosis | BLK, SCARB1, FGR, PTEN, SYK |
217 | GO:0045428 | 0.03 | 6.07 | 2.04 | 5 | 7 | regulation of nitric oxide biosynthetic process | TSPO, IGF1, IL10, PTGIS, RGN |
218 | GO:0002279 | 0.00 | 6.07 | 6.15 | 15 | 21 | mast cell activation involved in immune response | FCER1A, FGR, IL13, IL13RA2, KIT, PDPK1, RAC2, S100A13, STXBP2, SYK, LAT2, VAMP8, SNAP23, CD84, GAB2 |
219 | GO:0046686 | 0.00 | 6.07 | 6.15 | 15 | 21 | response to cadmium ion | ALAD, ARG1, CAT, CDK2, CYB5A, CYP1A2, GSS, PCNA, PPP5C, PTH, SLC34A1, SORD, SPARC, SLC30A1, AKR1C3 |
220 | GO:0014009 | 0.03 | 6.07 | 2.04 | 5 | 7 | glial cell proliferation | CLU, CREB1, PTK2B, PENK, SOX4 |
221 | GO:0007618 | 0.03 | 6.07 | 2.04 | 5 | 7 | mating | APLP2, APP, DRD5, HEXB, PTEN |
222 | GO:0043304 | 0.03 | 6.06 | 2.05 | 5 | 7 | regulation of mast cell degranulation | IL13RA2, PDPK1, RAC2, STXBP2, CD84 |
223 | GO:0000722 | 0.00 | 6.06 | 4.10 | 10 | 14 | telomere maintenance via recombination | FEN1, PCNA, PRIM2, RAD51, RFC1, RFC3, RFC4, RFC5, RPA2, RPA3 |
224 | GO:0001958 | 0.00 | 6.06 | 4.10 | 10 | 14 | endochondral ossification | BMP4, RUNX2, COL1A1, COL2A1, COL10A1, DLX5, FGFR3, GNAS, INPPL1, PEX7 |
225 | GO:0006883 | 0.00 | 6.06 | 4.10 | 10 | 14 | cellular sodium ion homeostasis | AGTR2, ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP4A, SGK1, SLC8A1, SLC9A1, SGK2 |
226 | GO:0045653 | 0.00 | 6.06 | 4.10 | 10 | 14 | negative regulation of megakaryocyte differentiation | PRMT1, HIST1H4I, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L |
227 | GO:0071542 | 0.00 | 6.06 | 4.10 | 10 | 14 | dopaminergic neuron differentiation | PHOX2A, EN1, FGF8, FOXA2, OTX2, RAC1, RYK, VEGFA, WNT1, PHOX2B |
228 | GO:2001267 | 0.00 | 6.06 | 4.10 | 10 | 14 | regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | BAX, CASP8, CD14, SMAD3, TRAF2, TRADD, RIPK1, TNFSF10, TNFRSF10B, TNFRSF10A |
229 | GO:0001976 | 0.03 | 6.05 | 2.05 | 5 | 7 | neurological system process involved in regulation of systemic arterial blood pressure | ADRA1B, AGTR2, RPS6KA2, SOD2, TNNI3 |
230 | GO:0003148 | 0.03 | 6.05 | 2.05 | 5 | 7 | outflow tract septum morphogenesis | FGF8, GATA6, ISL1, RARA, RARB |
231 | GO:0006105 | 0.03 | 6.05 | 2.05 | 5 | 7 | succinate metabolic process | GAD1, SDHA, SDHB, STAT5B, SUCLG1 |
232 | GO:0007063 | 0.03 | 6.05 | 2.05 | 5 | 7 | regulation of sister chromatid cohesion | ATRX, BUB1, RB1, SFPQ, TNKS |
233 | GO:0007350 | 0.03 | 6.05 | 2.05 | 5 | 7 | blastoderm segmentation | HOXD8, SEMA3F, T, FZD5, NRP1 |
234 | GO:0009820 | 0.03 | 6.05 | 2.05 | 5 | 7 | alkaloid metabolic process | BCHE, CYP1A2, CYP3A4, PTGIS, PTGS2 |
235 | GO:0014854 | 0.03 | 6.05 | 2.05 | 5 | 7 | response to inactivity | CASQ1, CAT, F2, IL10, SCN5A |
236 | GO:0015810 | 0.03 | 6.05 | 2.05 | 5 | 7 | aspartate transport | ABAT, NTSR1, SLC1A6, SLC25A12, SLC25A13 |
237 | GO:0019740 | 0.03 | 6.05 | 2.05 | 5 | 7 | nitrogen utilization | BAX, RHAG, RHCE, RHD, NR1H4 |
238 | GO:0033631 | 0.03 | 6.05 | 2.05 | 5 | 7 | cell-cell adhesion mediated by integrin | ADA, DPP4, ITGA5, ITGB1, PIEZO1 |
239 | GO:0035457 | 0.03 | 6.05 | 2.05 | 5 | 7 | cellular response to interferon-alpha | AXL, ENTPD2, GATA3, IFIT3, OAS1 |
240 | GO:0042268 | 0.03 | 6.05 | 2.05 | 5 | 7 | regulation of cytolysis | BAD, CSF2, GPLD1, P2RX7, PAX2 |
241 | GO:0043129 | 0.03 | 6.05 | 2.05 | 5 | 7 | surfactant homeostasis | CTSH, FGF7, KDR, SFTPD, VEGFA |
242 | GO:0043374 | 0.03 | 6.05 | 2.05 | 5 | 7 | CD8-positive, alpha-beta T cell differentiation | TNFSF8, IFNG, IRF1, SATB1, EOMES |
243 | GO:0048313 | 0.03 | 6.05 | 2.05 | 5 | 7 | Golgi inheritance | GOLGA2, MAPK1, MAPK3, VRK1, YWHAZ |
244 | GO:0050482 | 0.03 | 6.05 | 2.05 | 5 | 7 | arachidonic acid secretion | ANXA1, ACE, DRD3, NTSR1, SYK |
245 | GO:0051593 | 0.03 | 6.05 | 2.05 | 5 | 7 | response to folic acid | ASCL1, BCHE, MGMT, NRF1, TYMS |
246 | GO:0051597 | 0.03 | 6.05 | 2.05 | 5 | 7 | response to methylmercury | ALAD, ARG1, CCNE1, CPOX, HMBS |
247 | GO:0051709 | 0.03 | 6.05 | 2.05 | 5 | 7 | regulation of killing of cells of other organism | BAD, FCER2, IFNG, P2RX7, BCL2L11 |
248 | GO:0055022 | 0.03 | 6.05 | 2.05 | 5 | 7 | negative regulation of cardiac muscle tissue growth | CAV3, CXADR, KCNK2, TP73, CTDP1 |
249 | GO:0060045 | 0.03 | 6.05 | 2.05 | 5 | 7 | positive regulation of cardiac muscle cell proliferation | CCNB1, GATA4, GATA6, NRG1, RBPJ |
250 | GO:0060080 | 0.03 | 6.05 | 2.05 | 5 | 7 | inhibitory postsynaptic potential | ABAT, GLRA1, NTSR1, CX3CL1, RIMS2 |
251 | GO:0060134 | 0.03 | 6.05 | 2.05 | 5 | 7 | prepulse inhibition | DRD3, FABP7, GRID2, PTEN, NRXN1 |
252 | GO:0060253 | 0.03 | 6.05 | 2.05 | 5 | 7 | negative regulation of glial cell proliferation | ASCL2, TSPO, PTN, SOX11, RNF10 |
253 | GO:0060442 | 0.03 | 6.05 | 2.05 | 5 | 7 | branching involved in prostate gland morphogenesis | BMP4, CD44, IGF1, RXRA, FEM1B |
254 | GO:0060841 | 0.03 | 6.05 | 2.05 | 5 | 7 | venous blood vessel development | ACVR2B, ACVRL1, BMPR2, PROX1, VEGFA |
255 | GO:0060850 | 0.03 | 6.05 | 2.05 | 5 | 7 | regulation of transcription involved in cell fate commitment | BMP4, ETV2, EVX1, PROX1, NR2F2 |
256 | GO:0070669 | 0.03 | 6.05 | 2.05 | 5 | 7 | response to interleukin-2 | IL2RA, IL2RB, IL2RG, PTPN2, STAT5B |
257 | GO:0071415 | 0.03 | 6.05 | 2.05 | 5 | 7 | cellular response to purine-containing compound | CASQ2, P2RY2, RYR1, RYR2, SLC8A1 |
258 | GO:0090344 | 0.03 | 6.05 | 2.05 | 5 | 7 | negative regulation of cell aging | ABL1, CDK6, PTEN, WNT1, TP63 |
259 | GO:0097067 | 0.03 | 6.05 | 2.05 | 5 | 7 | cellular response to thyroid hormone stimulus | BMP4, KLF9, CTSH, CTSS, KIT |
260 | GO:1900119 | 0.03 | 6.05 | 2.05 | 5 | 7 | positive regulation of execution phase of apoptosis | BAX, BOK, FAP, PTGIS, RPS3 |
261 | GO:1903206 | 0.03 | 6.05 | 2.05 | 5 | 7 | negative regulation of hydrogen peroxide-induced cell death | EPOR, HGF, PSAP, PYCR1, TRAP1 |
262 | GO:0031100 | 0.00 | 5.96 | 9.06 | 22 | 31 | organ regeneration | ANGPT2, ANXA3, APOH, CCNE1, CDK2, CDK4, CDKN1A, EIF4A1, F7, FLT3, HGF, HMBS, IGF2R, MKI67, NRF1, PRPS2, SHC1, TYMS, WNT1, NR0B2, SOCS3, PTPRU |
263 | GO:0071260 | 0.00 | 5.93 | 14.05 | 34 | 48 | cellular response to mechanical stimulus | AQP1, ATP1A1, ATP1A2, BAD, BMP4, CASP5, CASP8, TNFRSF8, CD40, CHEK1, CNN2, COL1A1, CYBA, EDNRA, F2, IGF2, IL13, IL13RA2, IRF1, ITGA2, ITGB1, KCNJ2, MAPK3, PTGS2, RAC1, SLC9A1, SOX9, TNFRSF1A, CRADD, TNFSF14, TNFRSF10B, TNFRSF10A, BAG3, CASP8AP2 |
264 | GO:0002712 | 0.00 | 5.90 | 7.02 | 17 | 24 | regulation of B cell mediated immunity | BTK, C3, CD28, CD40, CR1, FCER1A, FCER2, HPX, IFNG, IL10, PTPN6, XCL1, STAT6, TNFSF4, UNG, TNFSF13, IL27RA |
265 | GO:0033683 | 0.00 | 5.90 | 7.02 | 17 | 24 | nucleotide-excision repair, DNA incision | DDB1, ERCC3, ERCC4, NTHL1, PCNA, RFC1, RFC3, RFC4, RFC5, RPA2, RPA3, RPS27A, UBB, XPA, CUL4A, CHD1L, RBX1 |
266 | GO:0002687 | 0.00 | 5.86 | 4.95 | 12 | 17 | positive regulation of leukocyte migration | ADAM8, BDKRB1, ICAM1, ITGA2, ITGA4, KITLG, PTAFR, SELE, SELP, ZP3, MADCAM1, TNFRSF18 |
267 | GO:0033002 | 0.00 | 5.84 | 12.85 | 31 | 44 | muscle cell proliferation | ANG, BMP4, COMT, CYBA, S1PR1, EDNRA, FLT1, HMGCR, ID2, IFNG, IGF1, IGFBP3, IL12B, IL13, ILK, IRAK1, ITGA2, JUN, ORC1, PTAFR, PTGS2, RPS6KB1, CX3CL1, SHC1, SKP2, STAT5B, VIP, VIPR2, XRCC5, KLF4, MFN2 |
268 | GO:0045879 | 0.00 | 5.82 | 4.98 | 12 | 17 | negative regulation of smoothened signaling pathway | RUNX2, CD3E, FGFR3, GPC3, PRKACB, PTCH1, RB1, RFX4, SALL1, TULP3, PTCH2, CHRD |
269 | GO:1901522 | 0.00 | 5.82 | 4.98 | 12 | 17 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus | ATF4, RUNX2, DLX5, EP300, FOXA2, RBPJ, SMAD1, SMAD9, RXRA, RXRG, USF1, VEGFA |
270 | GO:0071214 | 0.01 | 5.79 | 2.88 | 7 | 10 | cellular response to abiotic stimulus | ASCL1, GPLD1, INSRR, PCK1, PTAFR, SIPA1, RAB11B |
271 | GO:0034405 | 0.01 | 5.66 | 2.92 | 7 | 10 | response to fluid shear stress | F3, PTK2B, HAS2, P2RX4, P2RX7, PTGS2, IFT88 |
272 | GO:0033003 | 0.01 | 5.66 | 2.92 | 7 | 10 | regulation of mast cell activation | CNR1, IL13RA2, PDPK1, PTPRE, RAC2, STXBP2, CD84 |
273 | GO:0001710 | 0.01 | 5.65 | 2.93 | 7 | 10 | mesodermal cell fate commitment | BMP4, BMPR1A, ETV2, EYA2, SMAD1, PAX2, KLF4 |
274 | GO:0002507 | 0.01 | 5.65 | 2.93 | 7 | 10 | tolerance induction | C3, CBLB, CD3E, CD86, CLC, IL2RA, IDO1 |
275 | GO:0002902 | 0.01 | 5.65 | 2.93 | 7 | 10 | regulation of B cell apoptotic process | ADA, BAX, BTK, CD74, IL10, PTEN, AURKB |
276 | GO:0006828 | 0.01 | 5.65 | 2.93 | 7 | 10 | manganese ion transport | TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, ZP3, ATP2C2 |
277 | GO:0006837 | 0.01 | 5.65 | 2.93 | 7 | 10 | serotonin transport | CRH, FCER1A, GPM6B, P2RX1, SLC6A4, SNCA, SYK |
278 | GO:0017187 | 0.01 | 5.65 | 2.93 | 7 | 10 | peptidyl-glutamic acid carboxylation | BGLAP, F2, F7, F10, PROC, PROS1, PROZ |
279 | GO:0032878 | 0.01 | 5.65 | 2.93 | 7 | 10 | regulation of establishment or maintenance of cell polarity | KRIT1, PTK2B, FLOT2, GATA3, IGF1, LLGL2, RNF41 |
280 | GO:0035988 | 0.01 | 5.65 | 2.93 | 7 | 10 | chondrocyte proliferation | BMPR2, CTGF, FGFR3, IHH, LTF, DDR2, STC1 |
281 | GO:0042438 | 0.01 | 5.65 | 2.93 | 7 | 10 | melanin biosynthetic process | ASIP, CTNS, DCT, TRPC1, TYR, RAPGEF2, ZEB2 |
282 | GO:0044110 | 0.01 | 5.65 | 2.93 | 7 | 10 | growth involved in symbiotic interaction | CD36, CTSG, IFNG, IL10, IL12B, OSBP, PGLYRP1 |
283 | GO:0048268 | 0.01 | 5.65 | 2.93 | 7 | 10 | clathrin coat assembly | AP2B1, AP2S1, EPS15, HIP1, PIK3C2A, PICALM, SNAP91 |
284 | GO:0071257 | 0.01 | 5.65 | 2.93 | 7 | 10 | cellular response to electrical stimulus | ADSS, GNAT1, GRM1, IGF1, PALM, REST, SLC9A1 |
285 | GO:0072576 | 0.01 | 5.65 | 2.93 | 7 | 10 | liver morphogenesis | HPN, IFNG, MKI67, PROX1, PTN, RPS6KA1, CUL3 |
286 | GO:0086012 | 0.01 | 5.65 | 2.93 | 7 | 10 | membrane depolarization during cardiac muscle cell action potential | ATP1A2, CAV3, KCNJ2, SCN2B, SCN4B, SCN5A, SLC8A1 |
287 | GO:0090136 | 0.01 | 5.65 | 2.93 | 7 | 10 | epithelial cell-cell adhesion | CTNNA1, IHH, ITGB5, JUP, KIT, SRF, VCL |
288 | GO:0010107 | 0.00 | 5.56 | 6.73 | 16 | 23 | potassium ion import | ATP1A3, ATP12A, ATP4A, KCNJ1, KCNJ2, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ14, KCNJ16, SLC12A6, ABCC9 |
289 | GO:0002448 | 0.00 | 5.55 | 6.73 | 16 | 23 | mast cell mediated immunity | FCER1A, FGR, IL13, IL13RA2, KIT, PDPK1, SERPINB9, RAC2, S100A13, STXBP2, SYK, LAT2, VAMP8, SNAP23, CD84, GAB2 |
290 | GO:0033628 | 0.00 | 5.46 | 3.80 | 9 | 13 | regulation of cell adhesion mediated by integrin | ADA, DPP4, EFNA1, EPHA2, EPHA8, HRG, SERPINE1, PTK2, ITGB1BP1 |
291 | GO:0001963 | 0.00 | 5.46 | 3.80 | 9 | 13 | synaptic transmission, dopaminergic | CDK5, CHRNB2, CRH, CRHBP, DRD3, DRD5, GDNF, RAB3B, GPR52 |
292 | GO:0007413 | 0.00 | 5.45 | 3.80 | 9 | 13 | axonal fasciculation | CNR1, EPHA3, EPHA4, EPHB2, EPHB3, NRCAM, PTPRZ1, CNTN2, NRP1 |
293 | GO:0007597 | 0.00 | 5.45 | 3.80 | 9 | 13 | blood coagulation, intrinsic pathway | APOH, F2, F10, F12, GP1BA, GP9, KLKB1, KNG1, PRCP |
294 | GO:0015697 | 0.00 | 5.45 | 3.80 | 9 | 13 | quaternary ammonium group transport | ACACB, SLC25A20, CPT1B, CPT2, PRKAB2, SLC22A1, SLC22A3, SLC22A2, SLC22A5 |
295 | GO:0031000 | 0.00 | 5.45 | 3.80 | 9 | 13 | response to caffeine | CASQ2, DHODH, DNMT1, DNMT3B, IGF1, PRKAA1, RYR1, RYR2, SLC8A1 |
296 | GO:0046487 | 0.00 | 5.45 | 3.80 | 9 | 13 | glyoxylate metabolic process | BCKDHA, DAO, DBT, DLD, GLDC, IDH1, OGDH, PDHX, GRHPR |
297 | GO:0060260 | 0.00 | 5.45 | 3.80 | 9 | 13 | regulation of transcription initiation from RNA polymerase II promoter | AHR, CREB1, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, SRF, HNF1A |
298 | GO:0071364 | 0.00 | 5.45 | 3.80 | 9 | 13 | cellular response to epidermal growth factor stimulus | COL1A1, ID1, PAX2, PDPK1, SOX9, STAT5B, VIL1, IQGAP1, BAG4 |
299 | GO:0086019 | 0.00 | 5.45 | 3.80 | 9 | 13 | cell-cell signaling involved in cardiac conduction | CASQ2, CXADR, KCNA5, KCNQ1, RYR2, SCN4B, SCN5A, NUP155, HCN4 |
300 | GO:0051403 | 0.00 | 5.44 | 8.45 | 20 | 29 | stress-activated MAPK cascade | CAV3, CHUK, CREB1, CRYAB, DUSP7, ELK1, HGF, JUN, PRDX1, PPP2R5D, MAPK1, MAPK3, RBM4, RPS6KA1, RPS6KA2, RPS6KA3, SKP1, NR2C2, CUL1, RPS6KA5 |
301 | GO:0006977 | 0.00 | 5.40 | 13.17 | 31 | 45 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS27A, SOX4, UBB, CRADD, PSMF1, PSME3, PSMD14 |
302 | GO:1902400 | 0.00 | 5.40 | 13.17 | 31 | 45 | intracellular signal transduction involved in G1 DNA damage checkpoint | CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS27A, SOX4, UBB, CRADD, PSMF1, PSME3, PSMD14 |
303 | GO:0051928 | 0.00 | 5.38 | 4.65 | 11 | 16 | positive regulation of calcium ion transport | ATP2B2, TSPO, CACNB2, CAMK2A, CCR1, CRH, GCG, FFAR1, STC1, WFS1, ZP3 |
304 | GO:0042476 | 0.00 | 5.36 | 4.67 | 11 | 16 | odontogenesis | AQP1, AQP5, AQP6, BGLAP, COL1A1, EDNRA, PAM, PAX9, SDC1, TUFT1, ZNF22 |
305 | GO:0045582 | 0.00 | 5.35 | 4.67 | 11 | 16 | positive regulation of T cell differentiation | ADAM8, BAD, CD74, EGR3, GATA3, IL2RA, RAG1, STAT5B, TNFSF9, IL1RL2, VNN1 |
306 | GO:0006099 | 0.00 | 5.34 | 4.68 | 11 | 16 | tricarboxylic acid cycle | ACO2, DLD, IDH1, IDH3A, MDH2, OGDH, SDHA, SDHB, SDHC, SDHD, SUCLG1 |
307 | GO:0061418 | 0.00 | 5.34 | 4.68 | 11 | 16 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | ARNT, BACH1, EP300, RBPJ, RPS27A, UBB, UBE2D1, UBE2D2, VEGFA, CUL2, RBX1 |
308 | GO:0086004 | 0.00 | 5.34 | 4.68 | 11 | 16 | regulation of cardiac muscle cell contraction | ATP1A1, ATP1A2, GATA4, JUP, KCNJ2, PDE4B, PLN, RYR2, SCN5A, STC1, SUMO1 |
309 | GO:2000144 | 0.00 | 5.34 | 4.68 | 11 | 16 | positive regulation of DNA-templated transcription, initiation | AHR, CREB1, JUN, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, SRF, HNF1A, FOSL1 |
310 | GO:0048709 | 0.00 | 5.29 | 5.54 | 13 | 19 | oligodendrocyte differentiation | BOK, CDK5, CNP, NRG1, NTRK2, PTPRJ, PTPRZ1, SLC8A3, SOX5, SOX9, SOX10, TRPC4, VTN |
311 | GO:0010939 | 0.00 | 5.26 | 5.56 | 13 | 19 | regulation of necrotic cell death | SLC25A4, BIRC3, TSPO, CASP8, RPS27A, TRAF2, UBB, TRADD, RIPK1, TNFSF10, TNFRSF10B, TNFRSF10A, ARHGEF2 |
312 | GO:0032570 | 0.00 | 5.26 | 5.56 | 13 | 19 | response to progesterone | BAD, TSPO, C3, CCNE1, GJB2, JUNB, OXTR, PTGER2, PTN, SREBF1, TYMS, FOSL1, SOCS3 |
313 | GO:0060048 | 0.00 | 5.24 | 6.41 | 15 | 22 | cardiac muscle contraction | ADRBK1, ATP1A3, GAA, KCNA5, KCNH2, SCN2B, SCN4B, SRSF1, SNTA1, TAZ, TNNC1, TNNI2, TNNI3, VEGFB, NUP155 |
314 | GO:0002548 | 0.00 | 5.20 | 6.44 | 15 | 22 | monocyte chemotaxis | ANXA1, CCR1, FLT1, SERPINE1, RPS19, S100A7, S100A12, CCL21, CCL22, CCL25, XCL1, CX3CL1, XCL2, TNFSF18, SLIT2 |
315 | GO:0072350 | 0.00 | 5.20 | 6.44 | 15 | 22 | tricarboxylic acid metabolic process | ACO2, ASS1, DLD, GLUD1, IDH1, IDH3A, MDH2, OGDH, SDHA, SDHB, SDHC, SDHD, SLC34A1, STAT5B, SUCLG1 |
316 | GO:0034142 | 0.00 | 5.17 | 15.51 | 36 | 53 | toll-like receptor 4 signaling pathway | BIRC3, BTK, CASP8, CD14, CD36, CHUK, CREB1, DUSP7, ELK1, IRAK1, IRAK2, ITGAM, JUN, LTF, PPP2R5D, PRKCE, MAPK1, MAPK3, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, UBB, UBE2D1, UBE2D2, UBE2V1, CUL1, IKBKG, RIPK1, RIPK2, RPS6KA5, NR1D1, TRIL, NR1H4, TANK |
317 | GO:0021766 | 0.00 | 5.17 | 7.31 | 17 | 25 | hippocampus development | ANXA3, BBS4, CDK5, EPHA5, EZH1, KCNA1, OGDH, PTPRS, PTPRZ1, RARA, SRD5A1, SRF, TP73, TSC1, LRP8, USP9X, ZEB2 |
318 | GO:0043542 | 0.00 | 5.14 | 9.88 | 23 | 34 | endothelial cell migration | DPP4, EFNA1, EFNB2, EGR3, EPHA2, EMP2, FAP, FGF4, GPX1, NR4A1, ID1, ITGB1, PDPK1, PRCP, PRKX, PTEN, PTK2, S100A2, S100P, SRF, NR2E1, SCG2, TNFSF12 |
319 | GO:0045669 | 0.00 | 5.13 | 8.19 | 19 | 28 | positive regulation of osteoblast differentiation | ACVR2B, ATP6AP1, BMP4, BMPR1A, BMPR2, RUNX2, DLX5, GNAS, HGF, IGF1, ILK, JUND, LTF, SMAD1, DDR2, PRKD1, SOX11, TP63, PDLIM7 |
320 | GO:0008406 | 0.00 | 5.09 | 12.52 | 29 | 43 | gonad development | AHR, ANG, BMP4, BRCA2, CAPN5, CCNE1, CHAT, FANCF, FANCG, FGF7, FGF8, CENPI, GDF9, IDH1, KDR, PGR, PTPRN, SALL1, STAT5B, TSPY1, UBE3A, VEGFA, ZP3, NRIP1, FZD4, EIF2B2, BMP15, SLIT2, IRX5 |
321 | GO:0060135 | 0.00 | 5.09 | 9.95 | 23 | 34 | maternal process involved in female pregnancy | ADCY7, ANGPT2, ARG1, PRDM1, BMPR2, BSG, CNR1, CYP27B1, EPOR, GHSR, GJB2, IHH, ITGB1, JUNB, MEN1, PAM, PGR, PTGIS, PTGS2, RXRA, STC1, NR2F2, VDR |
322 | GO:0032496 | 0.00 | 5.06 | 27.31 | 63 | 94 | response to lipopolysaccharide | ADH5, ALAD, ATP4B, BCR, BDKRB1, CASP8, CASP9, TNFRSF8, CHUK, CNP, CNR1, COMT, CPS1, CTSG, CYP1A2, CYP27B1, DCN, DNMT1, EDNRA, F2R, F3, CXCL2, CXCL3, IGF1, IL10RA, IL12RB2, IL13, TNFRSF9, IDO1, JUN, JUNB, JUND, KCNJ8, NRF1, P2RX7, PENK, PF4V1, PROS1, PTGER1, PTGER2, PTGS2, RPS6KA3, RPS6KB1, S100A7, S100A8, CXCL6, CXCL5, SELE, SELP, SLPI, SNCA, SPARC, STAT5B, ADAM17, TNFRSF1A, SCGB1A1, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, SOCS3, NR1H4, IL18BP |
323 | GO:0045815 | 0.00 | 5.05 | 12.58 | 29 | 43 | positive regulation of gene expression, epigenetic | ACTB, CHEK1, EP300, ERCC6, KAT2A, H3F3B, HMGA1, PHF2, TBP, ARID1A, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, HIST1H3F, TAF1B, TAF1A, BAZ1B, DDX21 |
324 | GO:0071375 | 0.00 | 5.05 | 4.27 | 10 | 15 | cellular response to peptide hormone stimulus | ANXA5, CDC6, CRHBP, CYP11B1, GNRHR, NR4A1, MEN1, RANGAP1, WNT1, AKAP1 |
325 | GO:0007611 | 0.00 | 4.94 | 5.20 | 12 | 18 | learning or memory | STS, CRHBP, DBI, EGR2, AFF2, GM2A, GPI, MAN2B1, PRKAR1B, VIP, KCNAB1, FZD9 |
326 | GO:0065004 | 0.02 | 4.91 | 2.61 | 6 | 9 | protein-DNA complex assembly | RAD51, RAD51C, RAD51B, RAD51D, XRCC2, CDC45 |
327 | GO:0032200 | 0.02 | 4.88 | 2.62 | 6 | 9 | telomere organization | H3F3B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H3F |
328 | GO:0030574 | 0.00 | 4.87 | 11.41 | 26 | 39 | collagen catabolic process | ADAM10, COL1A1, COL2A1, COL4A3, COL4A5, COL4A6, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, COL10A1, COL11A1, COL15A1, COL19A1, CTSK, CTSS, FAP, ITGB1, PEPD, ADAM17, COL14A1, ADAM15, ADAMTS3, ADAMTS2 |
329 | GO:0001541 | 0.00 | 4.87 | 9.65 | 22 | 33 | ovarian follicle development | AHR, ANG, BAX, BCL2L1, BMP4, CAPN5, CCNE1, CHAT, CTNNA1, FANCF, FANCG, FGF7, ICAM1, INHA, KDR, KIT, KITLG, UBE3A, VEGFA, ZP3, EIF2B2, BMP15 |
330 | GO:0071300 | 0.00 | 4.87 | 9.66 | 22 | 33 | cellular response to retinoic acid | ABCA1, ABL2, AQP1, COL1A1, BRINP1, EPHA3, PTK2B, KRT13, NTRK3, PAX2, SERPINF1, RARA, RET, SLC6A4, SOX9, T, WNT11, ZNF35, FZD4, FZD7, OGT, KLF4 |
331 | GO:0010812 | 0.00 | 4.86 | 7.90 | 18 | 27 | negative regulation of cell-substrate adhesion | ACTN4, ACVRL1, ANGPT2, ARHGAP6, COL1A1, FBLN1, MEN1, SERPINE1, PTEN, PTPRZ1, SPOCK1, TBCD, WNT1, FZD4, FZD7, ADAM15, ITGB1BP1, SEMA3E |
332 | GO:0060443 | 0.00 | 4.86 | 7.90 | 18 | 27 | mammary gland morphogenesis | ARG1, BAX, BMP4, CAPN1, CAV3, CSF1R, EPHA2, ELF3, ETV4, ETV5, B4GALT1, PAX3, PGR, PTCH1, SLC12A2, STAT6, VDR, SLIT2 |
333 | GO:0030521 | 0.01 | 4.86 | 3.50 | 8 | 12 | androgen receptor signaling pathway | CCNE1, SCGB2A1, RAN, RB1, UBE3A, NRIP1, ARID1A, NR1I3 |
334 | GO:0009712 | 0.00 | 4.86 | 7.02 | 16 | 24 | catechol-containing compound metabolic process | ABAT, AGTR2, CHRNB2, COMT, DAO, DBH, DRD3, GATA3, GRIN2A, HPRT1, PAH, SNCB, SNCA, SULT1A3, TACR3, SNCAIP |
335 | GO:0043113 | 0.00 | 4.86 | 7.02 | 16 | 24 | receptor clustering | CACNA1A, CDK5, DLG2, DLG3, ETV5, FNTA, GLRB, ITGA4, ITGAL, PTN, MADCAM1, SSNA1, ITGB1BP1, NRXN1, NRXN2, PICK1 |
336 | GO:0051290 | 0.00 | 4.86 | 7.02 | 16 | 24 | protein heterotetramerization | RRM1, RRM2, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HIST1H3F |
337 | GO:0001754 | 0.02 | 4.86 | 2.63 | 6 | 9 | eye photoreceptor cell differentiation | IHH, OTX2, PTN, SOX9, STAT3, SLC4A7 |
338 | GO:0042092 | 0.02 | 4.86 | 2.63 | 6 | 9 | type 2 immune response | ECM1, IFNA2, IL10, IL18, STAT6, IL27RA |
339 | GO:0060420 | 0.02 | 4.86 | 2.63 | 6 | 9 | regulation of heart growth | CAV3, CXADR, KCNK2, TP73, COL14A1, CTDP1 |
340 | GO:0014910 | 0.02 | 4.86 | 2.63 | 6 | 9 | regulation of smooth muscle cell migration | ACE, IGFBP3, ILK, SERPINE1, SORL1, SLIT2 |
341 | GO:0042769 | 0.00 | 4.85 | 6.15 | 14 | 21 | DNA damage response, detection of DNA damage | DDB1, PCNA, RFC1, RFC3, RFC4, RFC5, RPA2, RPA3, RPS3, RPS27A, SOX4, UBB, CUL4A, RBX1 |
342 | GO:0060324 | 0.00 | 4.85 | 6.15 | 14 | 21 | face development | ALDH1A3, BBS4, COL1A1, DLX5, ITGA4, PAX9, MAPK1, MAPK3, RAF1, RARA, RRAS, SOX3, SRF, SGPL1 |
343 | GO:0014003 | 0.01 | 4.85 | 3.51 | 8 | 12 | oligodendrocyte development | ASCL1, CD9, LPAR1, EIF2B1, ID2, SOX11, EIF2B3, EIF2B2 |
344 | GO:0046189 | 0.02 | 4.85 | 2.63 | 6 | 9 | phenol-containing compound biosynthetic process | AGTR2, DAO, DBH, GATA3, PAH, SNCA |
345 | GO:0048485 | 0.02 | 4.85 | 2.63 | 6 | 9 | sympathetic nervous system development | PHOX2A, GATA3, GDNF, SOX4, SOX11, TP63 |
346 | GO:0046685 | 0.02 | 4.85 | 2.63 | 6 | 9 | response to arsenic-containing substance | ALAD, CDKN1A, CPOX, SERPINF1, PTEN, RBM4 |
347 | GO:0099622 | 0.02 | 4.85 | 2.63 | 6 | 9 | cardiac muscle cell membrane repolarization | CAV3, SCN4B, SCN5A, SNTA1, WDR1, AKAP9 |
348 | GO:0051894 | 0.00 | 4.85 | 4.39 | 10 | 15 | positive regulation of focal adhesion assembly | HRG, KDR, SMAD3, PTPRJ, RAC1, SDC4, TSC1, VEGFA, ITGB1BP1, PPM1F |
349 | GO:0014829 | 0.01 | 4.85 | 3.51 | 8 | 12 | vascular smooth muscle contraction | ACTA2, CHRM1, CHRM3, EDNRA, EDNRB, P2RX1, PIK3C2A, SLC8A1 |
350 | GO:0021952 | 0.01 | 4.85 | 3.51 | 8 | 12 | central nervous system projection neuron axonogenesis | CHRNB2, DCC, EPHA4, EPHB1, EPHB3, NR2E1, DCLK1, SLIT2 |
351 | GO:0051491 | 0.01 | 4.85 | 3.51 | 8 | 12 | positive regulation of filopodium assembly | DPYSL3, GPM6A, PALM, PRKCQ, RALA, CCL21, FSCN1, SRF |
352 | GO:0060334 | 0.01 | 4.85 | 3.51 | 8 | 12 | regulation of interferon-gamma-mediated signaling pathway | HPX, IFNG, IFNGR1, PTPN2, PTPN6, SUMO1, NR1H2, SOCS3 |
353 | GO:0071636 | 0.01 | 4.85 | 3.51 | 8 | 12 | positive regulation of transforming growth factor beta production | CREB1, SMAD3, PTGS2, XCL1, CX3CL1, WNT11, SERPINB7, ATP6AP2 |
354 | GO:0001660 | 0.02 | 4.84 | 2.63 | 6 | 9 | fever generation | CNR1, EDNRB, IL1A, IL1RN, PTGS2, TRPV1 |
355 | GO:0002070 | 0.02 | 4.84 | 2.63 | 6 | 9 | epithelial cell maturation | CDKN1A, PGR, RFX3, SIX3, TYMS, FEM1B |
356 | GO:0003215 | 0.02 | 4.84 | 2.63 | 6 | 9 | cardiac right ventricle morphogenesis | GATA3, GATA4, ISL1, SMARCD3, SOX4, HAND1 |
357 | GO:0010919 | 0.02 | 4.84 | 2.63 | 6 | 9 | regulation of inositol phosphate biosynthetic process | ADCYAP1R1, PTK2B, HRH1, NTSR1, PTAFR, SNCA |
358 | GO:0022038 | 0.02 | 4.84 | 2.63 | 6 | 9 | corpus callosum development | CDK5, LPAR1, EPHB2, EPHB3, PTPRS, RYK |
359 | GO:0030220 | 0.02 | 4.84 | 2.63 | 6 | 9 | platelet formation | ACTN1, CASP9, EP300, PTPN6, SRF, TAL1 |
360 | GO:0030825 | 0.02 | 4.84 | 2.63 | 6 | 9 | positive regulation of cGMP metabolic process | FZD2, GUCA1A, GUCA2A, GUCA2B, RCVRN, GUCA1C |
361 | GO:0032717 | 0.02 | 4.84 | 2.63 | 6 | 9 | negative regulation of interleukin-8 production | ANXA1, ANXA4, BCL3, BPI, IL10, KLF4 |
362 | GO:0033630 | 0.02 | 4.84 | 2.63 | 6 | 9 | positive regulation of cell adhesion mediated by integrin | PTPN6, RAC3, RET, CCL21, SYK, PIEZO1 |
363 | GO:0042053 | 0.02 | 4.84 | 2.63 | 6 | 9 | regulation of dopamine metabolic process | ABAT, CHRNB2, COMT, HPRT1, SNCA, TACR3 |
364 | GO:0042423 | 0.02 | 4.84 | 2.63 | 6 | 9 | catecholamine biosynthetic process | AGTR2, DAO, DBH, GATA3, PAH, SNCA |
365 | GO:0045064 | 0.02 | 4.84 | 2.63 | 6 | 9 | T-helper 2 cell differentiation | ANXA1, BCL3, CD86, GATA3, RARA, TNFSF4 |
366 | GO:0055098 | 0.02 | 4.84 | 2.63 | 6 | 9 | response to low-density lipoprotein particle | ABCA1, CD9, CD36, F3, ITGB1, SYK |
367 | GO:0060218 | 0.02 | 4.84 | 2.63 | 6 | 9 | hematopoietic stem cell differentiation | CDK6, CHD2, ACE, SRF, TAL1, XRCC5 |
368 | GO:0060259 | 0.02 | 4.84 | 2.63 | 6 | 9 | regulation of feeding behavior | CNR1, INS, STAT3, TACR3, TRH, IFT88 |
369 | GO:0072574 | 0.02 | 4.84 | 2.63 | 6 | 9 | hepatocyte proliferation | HPN, IFNG, MKI67, PROX1, PTN, RPS6KA1 |
370 | GO:0046545 | 0.00 | 4.77 | 17.27 | 39 | 59 | development of primary female sexual characteristics | ACVR1B, ADCYAP1R1, AHR, ANG, BAX, BCL2L1, BMP4, BRCA2, CAPN5, CCNE1, CHAT, COL9A3, CTNNA1, FANCF, FANCG, FGF7, FSHB, CENPI, FSHR, GDF9, ICAM1, IDH1, INHA, KDR, KIT, KITLG, PGR, PTPRN, STAT5B, UBB, UBE3A, VEGFA, ZP3, NRIP1, FZD4, SGPL1, EIF2B2, BMP15, SLIT2 |
371 | GO:0032355 | 0.00 | 4.75 | 24.88 | 56 | 85 | response to estradiol | ADCYAP1R1, AHR, ANXA1, ASS1, BAD, BMP4, BRCA2, C3, CASP8, CASP9, CAT, CCNE1, CD4, CDK2, COL1A1, CRHBP, CRYAB, CTGF, CYP1A2, DNMT1, DNMT3A, DNMT3B, DUSP1, ETS1, F3, FGA, GJB2, HMBS, IGF1, IGF2, IHH, IL10, ITGA2, KCNJ11, NRF1, OXTR, PAM, PENK, PTCH1, PTEN, PTGS2, PTN, RARA, RBBP8, SLC6A4, SLC34A1, SRD5A1, STAT3, STAT5B, TACR3, NR2F2, PRDM2, NRIP1, MBD4, SOCS3, RAMP3 |
372 | GO:0051291 | 0.00 | 4.74 | 12.83 | 29 | 44 | protein heterooligomerization | ACVRL1, BIRC3, CASP8, CHRNB2, CHRNB4, COL1A1, COL6A1, COL6A2, CLDN3, CTNNA1, GLRA1, GLRB, HBA1, HBA2, HBE1, ILK, ITPR3, JUP, KCNC2, P2RX1, PPP5C, PRKAA1, STXBP3, TRAF2, TSC1, OGT, TRADD, RIPK1, CLDN1 |
373 | GO:0072413 | 0.00 | 4.73 | 13.75 | 31 | 47 | signal transduction involved in mitotic cell cycle checkpoint | CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS27A, SOX4, UBB, CRADD, PSMF1, PSME3, PSMD14 |
374 | GO:1902402 | 0.00 | 4.73 | 13.75 | 31 | 47 | signal transduction involved in mitotic DNA damage checkpoint | CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS27A, SOX4, UBB, CRADD, PSMF1, PSME3, PSMD14 |
375 | GO:0070482 | 0.00 | 4.72 | 25.27 | 57 | 87 | response to oxygen levels | ABAT, ACTN4, ADA, AHCY, ALAD, ALAS2, ANG, ANGPT2, APAF1, ASCL2, CAT, CDK4, CDKN1A, CHAT, CHRNB2, COL1A1, CLDN3, CREB1, CRYAB, CTGF, DPP4, EDNRA, ERCC3, ETS1, PTK2B, FLT1, HMBS, IGF1, ITGA2, ITPR1, KCNA5, LIPC, SMAD3, NRF1, OXTR, P2RX3, PAM, PENK, PRKCB, PRKCQ, PYGM, RAF1, RYR1, RYR2, SCNN1B, CX3CL1, SHC1, SLC6A4, SOD3, SRF, STAT5B, ADAM17, HSP90B1, TRH, USF1, SOCS3, PDLIM1 |
376 | GO:0001508 | 0.00 | 4.70 | 10.19 | 23 | 35 | action potential | ATP1A1, ATP1A2, CACNA1A, CACNA1B, CACNB4, CHRNB4, GLRA1, GNAQ, KCNA5, KCNC2, KCNH2, KCNQ1, NRCAM, SCN2B, SCN4B, SLC8A1, SNTA1, YWHAH, CNTNAP1, AKAP7, AKAP6, NUP155, HCN4 |
377 | GO:0002790 | 0.00 | 4.70 | 8.39 | 19 | 29 | peptide secretion | ABCA1, ACVR2B, ANXA1, AQP1, CAMK2G, IL1RN, PTPRN, PTPRN2, RAB1A, RAF1, STXBP3, TACR2, HNF1A, VIP, TRPV1, LTBP4, RAB11B, EIF2AK3, RIMS2 |
378 | GO:0001707 | 0.00 | 4.66 | 10.24 | 23 | 35 | mesoderm formation | BMP4, BMPR1A, BMPR2, EPHA2, ETV2, EXT2, EYA2, ITGA2, ITGB1, SMAD1, SMAD3, PAX2, PRKAR1A, SNAI1, SRF, T, TAL1, KDM6A, WNT11, EOMES, CHRD, KLF4, HAND1 |
379 | GO:0034162 | 0.00 | 4.64 | 9.37 | 21 | 32 | toll-like receptor 9 signaling pathway | CHUK, CREB1, DUSP7, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK1, MAPK3, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, UBB, UBE2V1, CUL1, IKBKG, RIPK2, RPS6KA5 |
380 | GO:0046879 | 0.00 | 4.64 | 6.64 | 15 | 23 | hormone secretion | ACVR2B, CAMK2G, IL1RN, PTPRN, PTPRN2, RAB1A, RAF1, STXBP3, HNF1A, VIP, LTBP4, SNAP23, RAB11B, EIF2AK3, RIMS2 |
381 | GO:0007623 | 0.00 | 4.59 | 12.51 | 28 | 43 | circadian rhythm | AHCY, KLF9, CDK4, CRX, DBP, DDX5, EGR3, EP300, F7, ID1, JUN, JUND, KCND2, LIPC, NTRK2, NTRK3, SERPINE1, PTEN, RPS27A, SIX3, SKP1, SLC6A4, SLC9A3, SRD5A1, SREBF1, TYMS, UBB, CUL1 |
382 | GO:0045471 | 0.00 | 4.56 | 23.41 | 52 | 80 | response to ethanol | ABAT, ADCY7, ADCYAP1R1, ALAD, ATP5G3, BAD, BGLAP, CASP8, CAT, CCNE1, CD14, CDK2, CDO1, CHAT, CHRNB2, CNR1, CRH, CRHBP, DBH, DNMT1, DNMT3A, PTK2B, FYN, GATA3, GLRA1, GOT2, GRIN2A, HMGCR, HMGCS2, ICAM1, IGF2, IL13, KCNC2, MGMT, NTRK3, OXCT1, PENK, PRKAA1, PRKCE, PTEN, PTH, RARA, RPS6KB1, RXRA, S100A8, SLC2A4, SPARC, STAT3, STAT5B, TRH, TYMS, PSMD14 |
383 | GO:0006284 | 0.00 | 4.55 | 6.73 | 15 | 23 | base-excision repair | ERCC6, FEN1, HMGA1, NTHL1, PCNA, RFC1, RFC3, RFC4, RFC5, RPA2, RPA3, UNG, WRN, PARG, MBD4 |
384 | GO:0007622 | 0.00 | 4.55 | 6.73 | 15 | 23 | rhythmic behavior | ADA, AHCY, ALB, CHRNB2, CRH, DRD3, EGR2, GHRHR, ID2, KCND2, PTEN, SIX3, SRD5A1, PER3, USP2 |
385 | GO:0032922 | 0.00 | 4.55 | 6.73 | 15 | 23 | circadian regulation of gene expression | AHR, ARNTL, ATF4, CRY2, CSNK1D, DRD3, ID2, PPP1CA, TOP1, NRIP1, OGT, PER3, USP2, NR1D1, CLOCK |
386 | GO:1903201 | 0.00 | 4.55 | 6.73 | 15 | 23 | regulation of oxidative stress-induced cell death | ATF4, EPOR, GPX1, HGF, HSPB1, INS, PSAP, PYCR1, SFPQ, SOD2, TRPM2, VNN1, BAG5, HDAC6, TRAP1 |
387 | GO:0001666 | 0.00 | 4.53 | 23.83 | 53 | 82 | response to hypoxia | ABAT, ACTN4, ADA, AHCY, ALAD, ALAS2, ANG, ANGPT2, APAF1, ASCL2, CAT, CHAT, CHRNB2, CLDN3, CREB1, CRYAB, DNMT3B, DPP4, EDNRA, ERCC3, ETS1, PTK2B, FLT1, HMBS, IGF1, ITGA2, ITPR1, KCNA5, LIPC, SMAD3, NRF1, P2RX3, PAM, PENK, PRKCB, PRKCQ, PYGM, RAF1, RYR1, RYR2, SCNN1B, CX3CL1, SHC1, SLC6A4, SOD3, SRF, STAT5B, ADAM17, HSP90B1, TRH, USF1, SOCS3, PDLIM1 |
388 | GO:0001938 | 0.00 | 4.52 | 11.71 | 26 | 40 | positive regulation of endothelial cell proliferation | ACVRL1, ANG, ARG1, ARNT, BMP4, BMPR2, CCR3, CYBA, ECM1, EGR3, F3, FGFR3, FLT4, NR4A1, JUN, KDR, PRKD1, PROX1, VEGFA, VEGFB, VIP, SCG2, TNFSF12, NRP2, NRP1, PDCD6 |
389 | GO:1901888 | 0.00 | 4.52 | 11.71 | 26 | 40 | regulation of cell junction assembly | ACVRL1, ARHGAP6, DAPK3, ACE, EFNA5, EPHA3, GPM6B, RAPGEF1, HRG, KDR, SMAD3, PTEN, PTK2, PTPRJ, RAC1, RAP1A, SDC4, SLC9A1, SNAI1, TSC1, VEGFA, FZD5, ITGB1BP1, PPM1F, RAPGEF2, SLK |
390 | GO:0031018 | 0.00 | 4.52 | 5.84 | 13 | 20 | endocrine pancreas development | ANXA1, CLU, NR5A2, FOXA2, HNF4G, ONECUT1, IAPP, INS, SLC2A2, SOX4, SOX9, EIF2AK3, ONECUT2 |
391 | GO:0055078 | 0.00 | 4.52 | 5.84 | 13 | 20 | sodium ion homeostasis | AGTR1, ANPEP, AVPR2, COMT, DRD3, EDNRB, KNG1, SCN7A, SCNN1A, SCNN1B, SCNN1G, UPK3A, CYP4F2 |
392 | GO:0033555 | 0.00 | 4.52 | 5.84 | 13 | 20 | multicellular organismal response to stress | ADCYAP1R1, DBI, DPP4, EIF4E, GABRA5, HMGCS2, HTR2C, IDO1, PENK, PTEN, RPS6KB1, NR2E1, VDAC1 |
393 | GO:0045445 | 0.00 | 4.52 | 5.84 | 13 | 20 | myoblast differentiation | CSRP2, FGF6, NRG1, HMGCR, IGF1, RBPJ, ISL1, RB1, REST, SDC1, SRF, T, KCNAB1 |
394 | GO:0007585 | 0.00 | 4.51 | 5.85 | 13 | 20 | respiratory gaseous exchange | PHOX2A, BPGM, COX15, CSF2RB, EDNRA, ELN, FUT8, HNMT, NTSR1, SFTPB, SFTPD, TMPRSS11D, TRAF4 |
395 | GO:0048008 | 0.00 | 4.51 | 5.85 | 13 | 20 | platelet-derived growth factor receptor signaling pathway | ABL1, ABL2, BCR, F3, F7, RAPGEF1, PIK3C2A, PTEN, VEGFA, IQGAP1, NRP1, SGPL1, BCAR1 |
396 | GO:0006953 | 0.00 | 4.51 | 5.85 | 13 | 20 | acute-phase response | ASS1, CRP, F2, FGA, HP, INS, ITIH4, ORM2, REG3A, SAA4, STAT3, STAT5B, CD163 |
397 | GO:0000083 | 0.00 | 4.51 | 5.85 | 13 | 20 | regulation of transcription involved in G1/S transition of mitotic cell cycle | BACH1, CCNE1, CDC6, DHFR, E2F6, ID2, ORC1, PCNA, RB1, RRM2, TYMS, CDC45, KLF11 |
398 | GO:0019228 | 0.00 | 4.51 | 5.85 | 13 | 20 | neuronal action potential | DPP6, IFNG, KCNA1, KCND2, P2RX1, P2RX3, P2RX4, SCN1A, SCN2A, SCN5A, SCN7A, SCN8A, KCNMB2 |
399 | GO:0032092 | 0.00 | 4.46 | 9.95 | 22 | 34 | positive regulation of protein binding | ABL1, ABL2, ADD1, BMP4, KRIT1, CDK5, EP300, EPB41, GCG, ITGA2, MEN1, RAN, RFNG, SPTA1, TRAF2, VTN, NRP1, ARHGEF7, TNFSF18, EIF2AK3, TRAF4, RAPGEF2 |
400 | GO:0060337 | 0.00 | 4.46 | 4.96 | 11 | 17 | type I interferon signaling pathway | BST2, IFI6, IFIT1, IFIT3, IRF1, IRF5, ISG20, OAS1, OAS3, SP100, OASL |
401 | GO:0071385 | 0.00 | 4.46 | 4.97 | 11 | 17 | cellular response to glucocorticoid stimulus | AHR, ANXA1, ATP2B1, KLF9, FLT3, HMGCS2, ISL1, REST, SGK1, STC1, UBE2L3 |
402 | GO:0051251 | 0.00 | 4.45 | 13.11 | 29 | 45 | positive regulation of lymphocyte activation | ADAM8, AXL, CD3D, CD3G, CD5, CTLA4, DPP4, EFNB2, EGR3, FLOT2, FLT3LG, FYN, GATA3, GRB2, IHH, PDPK1, PTPN6, RAC1, RAG1, RARA, CCL21, TRAF2, VAV1, AP3B1, TNFSF14, IL1RL2, VNN1, AP3D1, GRAP2 |
403 | GO:0002479 | 0.00 | 4.45 | 14.05 | 31 | 48 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | CD36, CYBA, ITGAV, ITGB5, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS27A, UBB, PSMF1, PSME3, PSMD14 |
404 | GO:0006595 | 0.00 | 4.45 | 18.14 | 40 | 62 | polyamine metabolic process | ARG1, ARG2, ASL, ASS1, CKM, CPS1, DHPS, GATM, OAZ1, OAZ2, ODC1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, SAT1, SLC6A8, SMS, PSMF1, SLC25A15, PSME3, PSMD14 |
405 | GO:0002639 | 0.00 | 4.45 | 4.98 | 11 | 17 | positive regulation of immunoglobulin production | CD28, CD37, CD40, HPX, IFNG, IL13, XCL1, STAT6, TNFSF4, UNG, TNFSF13 |
406 | GO:0010712 | 0.00 | 4.45 | 4.98 | 11 | 17 | regulation of collagen metabolic process | BMP4, CTGF, F2, F2R, FAP, IHH, ITGA2, ITGB1, CIITA, RAP1A, SERPINB7 |
407 | GO:0015872 | 0.00 | 4.45 | 4.98 | 11 | 17 | dopamine transport | ABAT, CHRNB2, CNR1, DRD3, GDNF, PCP4, RAB3B, SLC22A1, SLC22A3, SLC22A2, SNCA |
408 | GO:0043267 | 0.00 | 4.45 | 4.98 | 11 | 17 | negative regulation of potassium ion transport | ATF4, CASQ2, CAV3, PTK2B, KCNA5, KCNH2, KCNQ1, SUMO1, VIP, KCNAB1, OXSR1 |
409 | GO:0045003 | 0.00 | 4.45 | 4.98 | 11 | 17 | double-strand break repair via synthesis-dependent strand annealing | BARD1, BRCA2, RAD51, RAD51C, RAD51B, RAD51D, RBBP8, WRN, XRCC2, EXO1, RAD50 |
410 | GO:0046688 | 0.00 | 4.45 | 4.98 | 11 | 17 | response to copper ion | AQP1, BAX, ICAM1, IL1A, LCAT, LIPC, PAM, S100A13, SNCA, SOD3, SORD |
411 | GO:0071378 | 0.00 | 4.45 | 4.98 | 11 | 17 | cellular response to growth hormone stimulus | CSH1, GH2, MAPK1, MAPK3, PRL, PTK2, PTPN6, STAT3, STAT5B, ADAM17, SOCS3 |
412 | GO:1901031 | 0.00 | 4.45 | 4.98 | 11 | 17 | regulation of response to reactive oxygen species | CD36, DHFR, EPOR, HGF, HP, PSAP, PYCR1, SNCA, RGN, HDAC6, TRAP1 |
413 | GO:0043279 | 0.01 | 4.42 | 4.06 | 9 | 14 | response to alkaloid | ADA, BCHE, EDNRA, FGA, PPP2R2A, PPP5C, PRKCE, UQCRC1, PEA15 |
414 | GO:0031668 | 0.01 | 4.40 | 4.07 | 9 | 14 | cellular response to extracellular stimulus | AES, ASGR1, AXL, ITGA6, NUDT1, P2RX7, SIPA1, SKP2, FOSL1 |
415 | GO:0031016 | 0.01 | 4.39 | 4.08 | 9 | 14 | pancreas development | ACVR2B, HHEX, IGF1, IGF1R, IGF2, IHH, ISL1, PROX1, IFT88 |
416 | GO:0030850 | 0.01 | 4.37 | 4.09 | 9 | 14 | prostate gland development | AHR, ALOX15B, ANXA1, SERPINF1, PSAP, PTEN, RARA, SMARCC1, UBE3A |
417 | GO:0006521 | 0.00 | 4.37 | 15.51 | 34 | 53 | regulation of cellular amino acid metabolic process | BHMT, COMT, GATA3, HPN, INS, OAZ1, OAZ2, ODC1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PSMF1, NR1H4, PSME3, PSMD14 |
418 | GO:0031571 | 0.00 | 4.37 | 15.51 | 34 | 53 | mitotic G1 DNA damage checkpoint | CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPA2, RPS27A, SOX4, TP73, UBB, TP63, CRADD, PSMF1, PSME3, PSMD14 |
419 | GO:0007274 | 0.01 | 4.36 | 4.10 | 9 | 14 | neuromuscular synaptic transmission | CACNA1A, CHRM1, CHRNB2, CHRNB4, DTNA, EGR3, ETV5, P2RX3, RAB3A |
420 | GO:0010575 | 0.01 | 4.36 | 4.10 | 9 | 14 | positive regulation of vascular endothelial growth factor production | ARNT, ATF4, C3, FLT4, GATA4, IL1A, ISL1, PTGS2, EIF2AK3 |
421 | GO:0021871 | 0.01 | 4.36 | 4.10 | 9 | 14 | forebrain regionalization | BMP4, EMX1, EMX2, FGF8, TRA2B, SIX3, NR2F1, WNT1, EOMES |
422 | GO:0031641 | 0.01 | 4.36 | 4.10 | 9 | 14 | regulation of myelination | HGF, NRG1, IFNG, PTEN, RARA, RARB, RXRA, EIF2AK3, RNF10 |
423 | GO:0045191 | 0.01 | 4.36 | 4.10 | 9 | 14 | regulation of isotype switching | CD28, CD40, IFNG, IL10, STAT6, TNFSF4, UNG, TNFSF13, IL27RA |
424 | GO:0046641 | 0.01 | 4.36 | 4.10 | 9 | 14 | positive regulation of alpha-beta T cell proliferation | CD3E, CD28, CD55, IL12B, IL18, XCL1, SYK, TNFSF4, RIPK2 |
425 | GO:0048566 | 0.01 | 4.36 | 4.10 | 9 | 14 | embryonic digestive tract development | ADA, FGF9, GATA4, ID2, IHH, PCSK5, RARB, SALL1, SOX11 |
426 | GO:0070897 | 0.01 | 4.36 | 4.10 | 9 | 14 | DNA-templated transcriptional preinitiation complex assembly | AHR, CREB1, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, TAF7, TAF1B |
427 | GO:0044259 | 0.00 | 4.36 | 18.73 | 41 | 64 | multicellular organismal macromolecule metabolic process | ADAM10, ARG1, BMP4, COL1A1, COL2A1, COL4A3, COL4A5, COL4A6, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, COL10A1, COL11A1, COL15A1, COL19A1, CTGF, CTSK, CTSS, ACE, ENPEP, F2, F2R, FAP, ID1, IHH, ITGA2, ITGB1, CIITA, P2RX7, PEPD, RAP1A, ADAM17, COL14A1, AKR1C3, SERPINB7, ADAM15, ADAMTS3, ADAMTS2 |
428 | GO:0070848 | 0.04 | 4.35 | 2.22 | 5 | 8 | response to growth factor | ANXA3, EPHA2, KCNC2, P2RY2, HDAC6 |
429 | GO:0055024 | 0.00 | 4.32 | 7.32 | 16 | 25 | regulation of cardiac muscle tissue development | BMP4, CAV3, CCNB1, CXADR, EFNB2, FGF3, FGF8, GATA4, GATA6, NRG1, RBPJ, KCNK2, TP73, COL14A1, CTDP1, AKAP6 |
430 | GO:0034138 | 0.00 | 4.26 | 12.88 | 28 | 44 | toll-like receptor 3 signaling pathway | BIRC3, CASP8, CD14, CD86, CHUK, CREB1, DUSP7, ELK1, IRAK1, IRAK2, JUN, PPP2R5D, MAPK1, MAPK3, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SKP1, UBB, UBE2D1, UBE2D2, CUL1, IKBKG, RIPK1, RIPK2, RPS6KA5, TANK |
431 | GO:0070252 | 0.00 | 4.26 | 12.88 | 28 | 44 | actin-mediated cell contraction | ATP1A1, ATP1A2, CAV3, EMP2, GATA4, JUP, KCNA5, KCNH2, KCNJ2, KCNQ1, PDE4B, PLN, RYR2, SCN2B, SCN4B, SCN5A, SLC9A1, SNTA1, STC1, TNNC2, TNNC1, TNNI2, TNNI3, TPM2, SUMO1, VIL1, VIM, NUP155 |
432 | GO:0098657 | 0.00 | 4.26 | 6.43 | 14 | 22 | import into cell | DRD3, GDNF, GFAP, GPM6B, ITGA4, KCNJ10, NTSR1, RAB3B, SLC6A4, SLC8A3, SLC22A3, SNAP25, SNCA, PICALM |
433 | GO:0046209 | 0.00 | 4.26 | 9.66 | 21 | 33 | nitric oxide metabolic process | AGTR2, ARG2, ASS1, TSPO, CALM3, CLU, CPS1, DHFR, DNM2, PTK2B, ICAM1, IFNG, IGF1, IL10, INS, P2RX4, PTGIS, PTGS2, TRPV1, RGN, KLF4 |
434 | GO:0019369 | 0.02 | 4.25 | 3.21 | 7 | 11 | arachidonic acid metabolic process | ALOX15B, DAGLA, DPEP1, FAAH, GPX1, LTA4H, MAPK3 |
435 | GO:0061053 | 0.02 | 4.25 | 3.21 | 7 | 11 | somite development | IHH, PTCH1, RAD51B, RBBP6, SOX11, WNT1, WNT11 |
436 | GO:0001954 | 0.02 | 4.25 | 3.21 | 7 | 11 | positive regulation of cell-matrix adhesion | CD36, CDK6, EMP2, PTK2B, ILK, CCL21, CCL25 |
437 | GO:0050798 | 0.02 | 4.25 | 3.21 | 7 | 11 | activated T cell proliferation | ABL1, CLC, FYN, ITGAD, ITGAL, PRKAR1A, SATB1 |
438 | GO:0000272 | 0.00 | 4.25 | 6.44 | 14 | 22 | polysaccharide catabolic process | ADRA1B, CALM3, CPS1, G6PC, GAA, INS, PHKA2, PHKB, PHKG1, PPP1CA, PYGB, PYGM, MGAM, STBD1 |
439 | GO:0021983 | 0.00 | 4.25 | 6.44 | 14 | 22 | pituitary gland development | NR0B1, BMP4, BMPR1A, CDH1, CREB1, ETS1, FGF8, GHRHR, RBPJ, ISL1, SALL1, SIX3, SOX3, SRD5A1 |
440 | GO:0045070 | 0.00 | 4.25 | 6.44 | 14 | 22 | positive regulation of viral genome replication | ADAR, CD28, DDB1, DDX3X, NR5A2, IFIT1, PPIB, PPID, SRPK2, STAU1, TARBP2, TOP2A, VAPB, VAPA |
441 | GO:0010922 | 0.02 | 4.24 | 3.22 | 7 | 11 | positive regulation of phosphatase activity | AGTR2, CALM3, IFNG, ITGA1, PPP1R12A, RGN, AKAP6 |
442 | GO:0001941 | 0.02 | 4.24 | 3.22 | 7 | 11 | postsynaptic membrane organization | ETV5, FNTA, GDNF, GLRB, PTN, NRXN1, NRXN2 |
443 | GO:0020027 | 0.02 | 4.24 | 3.22 | 7 | 11 | hemoglobin metabolic process | ADD1, ALAS2, CAT, HPX, PRMT1, INHA, KLF4 |
444 | GO:0031639 | 0.02 | 4.24 | 3.22 | 7 | 11 | plasminogen activation | APOH, F12, FGA, HPN, KLKB1, SERPINE1, CLEC3B |
445 | GO:0032303 | 0.02 | 4.24 | 3.22 | 7 | 11 | regulation of icosanoid secretion | AGTR2, NTSR1, P2RX4, P2RX7, P2RY2, SYK, CYP4F2 |
446 | GO:0042762 | 0.02 | 4.24 | 3.22 | 7 | 11 | regulation of sulfur metabolic process | BHMT, COMT, DLD, PDK4, SNCA, SP1, PDHX |
447 | GO:0042921 | 0.02 | 4.24 | 3.22 | 7 | 11 | glucocorticoid receptor signaling pathway | ARNTL, CRY2, PHB, PPP5C, YWHAH, ARID1A, CLOCK |
448 | GO:0045086 | 0.02 | 4.24 | 3.22 | 7 | 11 | positive regulation of interleukin-2 biosynthetic process | CD3E, CD4, CD28, CD86, IL1A, PRKCQ, STAT5B |
449 | GO:0045911 | 0.02 | 4.24 | 3.22 | 7 | 11 | positive regulation of DNA recombination | CD28, CD40, IFNG, STAT6, TNFSF4, UNG, TNFSF13 |
450 | GO:0051000 | 0.02 | 4.24 | 3.22 | 7 | 11 | positive regulation of nitric-oxide synthase activity | AGTR2, CALM3, SCARB1, DHFR, PTK2B, FCER2, INS |
451 | GO:0060323 | 0.02 | 4.24 | 3.22 | 7 | 11 | head morphogenesis | COL1A1, DLX5, IHH, PAX9, RRAS, SGPL1, ATP6AP2 |
452 | GO:0060444 | 0.02 | 4.24 | 3.22 | 7 | 11 | branching involved in mammary gland duct morphogenesis | CAV3, EPHA2, ETV4, ETV5, PGR, SLC12A2, VDR |
453 | GO:1902176 | 0.02 | 4.24 | 3.22 | 7 | 11 | negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | GPX1, HSPB1, INS, SOD2, VNN1, BAG5, TRAP1 |
454 | GO:1903306 | 0.02 | 4.24 | 3.22 | 7 | 11 | negative regulation of regulated secretory pathway | BCR, IL13RA2, RAP1A, REST, STXBP3, SYT4, CD84 |
455 | GO:2000300 | 0.02 | 4.24 | 3.22 | 7 | 11 | regulation of synaptic vesicle exocytosis | PFN2, SEPT5, RAB3A, RAB5A, RAP1A, SYN1, RIMS3 |
456 | GO:0043154 | 0.00 | 4.24 | 15.22 | 33 | 52 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | BIRC3, XIAP, BIRC5, AQP1, CASP8, CD44, CDKN2D, CRYAB, CSNK2A1, DDX3X, DPEP1, IFI6, GPI, GPX1, HGF, PAX2, SERPINB9, RAF1, RAG1, RPS6KA1, RPS6KA3, SIAH2, SNCA, TRAF2, VEGFA, VIL1, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, KLF4 |
457 | GO:0040012 | 0.05 | 4.23 | 2.26 | 5 | 8 | regulation of locomotion | CHRM1, DRD3, EFNB2, SNCA, USP14 |
458 | GO:0022617 | 0.00 | 4.21 | 19.90 | 43 | 68 | extracellular matrix disassembly | ADAM8, ADAM10, BMP1, BSG, CAPN1, CD44, CDH1, COL1A1, COL2A1, COL4A3, COL4A5, COL4A6, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, COL10A1, COL11A1, COL15A1, COL19A1, CTRB1, CTSG, CTSK, CTSS, DCN, DPP4, ELN, ETS1, FAP, FBN1, HPN, KLK2, KLKB1, LAMA3, DDR2, FSCN1, ADAM17, TPSAB1, COL14A1, ADAM15, ADAMTS4 |
459 | GO:0072401 | 0.00 | 4.20 | 14.34 | 31 | 49 | signal transduction involved in DNA integrity checkpoint | CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS27A, SOX4, UBB, CRADD, PSMF1, PSME3, PSMD14 |
460 | GO:0010907 | 0.00 | 4.16 | 5.56 | 12 | 19 | positive regulation of glucose metabolic process | ADRA1B, GCG, KAT2A, GPLD1, IGF1, IGF2, INS, PTH, PTPN2, DYRK2, RGN, EPM2AIP1 |
461 | GO:0034694 | 0.00 | 4.16 | 5.56 | 12 | 19 | response to prostaglandin | GNAS, HMGCS2, P2RY4, P2RY6, PRKAA1, PRKCE, PTGDR, PTGER2, CCL21, TNFSF4, YY1, AKR1C3 |
462 | GO:0060487 | 0.00 | 4.16 | 5.56 | 12 | 19 | lung epithelial cell differentiation | ASCL1, CREB1, GATA6, FOXA2, IGF1, RBPJ, IL13, LTA4H, NUMA1, SOX9, AIMP2, NUMB |
463 | GO:0071715 | 0.00 | 4.16 | 5.56 | 12 | 19 | icosanoid transport | AGTR2, ANXA1, ACE, DRD3, NTSR1, P2RX4, P2RX7, P2RY2, SLCO2A1, SYK, CYP4F2, ABCC4 |
464 | GO:0009615 | 0.00 | 4.15 | 12.51 | 27 | 43 | response to virus | ACTA2, BAD, BCL2L1, BCL3, CDK6, CHUK, CLU, DDX1, DDX3X, FGR, GATA3, HMGA1, HSPB1, IFNGR1, ODC1, PENK, PSMA2, CCL22, XCL1, TPT1, TNFSF4, FOSL1, IKBKG, PRKRA, DDX21, DCLK1, BCL2L11 |
465 | GO:0030195 | 0.00 | 4.13 | 7.90 | 17 | 27 | negative regulation of blood coagulation | ABAT, ANXA5, APOH, F2, F12, FAP, FGA, GP1BA, HRG, KLKB1, KNG1, SERPINE1, PRKG1, PROC, PROS1, USF1, VTN |
466 | GO:0038061 | 0.00 | 4.12 | 17.24 | 37 | 59 | NIK/NF-kappaB signaling | ACTN4, ALK, BIRC3, CHUK, PPP4C, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS3, RPS27A, SKP1, UBB, CUL1, UBA3, PSMF1, RASSF2, PSME3, PSMD14 |
467 | GO:0038095 | 0.00 | 4.11 | 48.87 | 104 | 167 | Fc-epsilon receptor signaling pathway | ANGPT1, ARAF, BAD, BTK, CALM3, CAMK2A, CAMK2G, CASP9, CD28, CD86, CDKN1A, CHUK, CREB1, CSF2, CSF2RB, DUSP5, DUSP7, DUSP9, FCER1A, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FYN, GRB2, GRIN2A, NRG1, NR4A1, IL2RA, IL2RB, IL2RG, IL3, ITPR1, ITPR3, JUN, KIT, MARK3, KITLG, FOXO4, PDPK1, PPP5C, PRKCQ, MAPK1, MAPK3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, PTPRA, RAC1, RAF1, RASA2, RPS6KB2, RPS27A, SHC1, SKP1, SPTA1, SPTB, SYK, UBB, UBE2D1, UBE2D2, UBE2V1, VAV1, LAT2, FGF23, CUL3, CUL1, IKBKG, PEA15, KL, GRAP2, PSMF1, NRG2, RAPGEF2, GAB2, RBX1, AKAP9, RASA4, PSME3, PSMD14 |
468 | GO:0043434 | 0.00 | 4.11 | 13.32 | 29 | 47 | response to peptide hormone | ANXA1, STS, BSG, CAT, COL1A1, CTGF, EGR2, EIF2B1, GNAI1, HADHA, IL10, INPPL1, JUNB, JUND, LIPC, LTA4H, OXTR, PCK1, PLN, PTPRN, SORT1, SLC2A2, SPARC, STXBP3, TRPV1, EIF2B3, EIF2B2, RNF40, EPM2AIP1 |
469 | GO:0097696 | 0.01 | 4.07 | 4.65 | 10 | 16 | STAT cascade | CSH1, GH2, MAPK1, MAPK3, PTPN6, STAT2, STAT3, STAT4, STAT5B, ADAM17 |
470 | GO:0045931 | 0.01 | 4.06 | 4.66 | 10 | 16 | positive regulation of mitotic cell cycle | ABL1, ASNS, BRCA2, CCNB1, EIF4E, MAD2L1, RPS6KB1, STAT5B, TAL1, USP2 |
471 | GO:0007202 | 0.00 | 4.06 | 11.71 | 25 | 40 | activation of phospholipase C activity | ADCY1, ADCY7, ADCYAP1R1, ADRBK1, ANG, ARHGAP6, AVPR1B, CALM3, CREB1, LPAR1, EDNRA, GNA15, GNAQ, ITPR1, ITPR3, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, SELE, S1PR4, GPR55 |
472 | GO:0006937 | 0.00 | 4.05 | 15.43 | 33 | 53 | regulation of muscle contraction | ADRBK1, ANXA6, ATP1A1, ATP2A1, CALM3, CASQ1, CASQ2, CAV3, CTGF, GATA4, HRC, JUP, KCNA1, KCNJ2, KCNQ1, SMAD7, PPP1R12B, P2RX4, PDE4B, PLN, RYR2, SCN5A, SLC8A1, SLC8A3, SLC9A1, STC1, TNNC2, TNNC1, TNNI2, SUMO1, PDE5A, GSTO1, HCN4 |
473 | GO:0051893 | 0.01 | 4.05 | 4.67 | 10 | 16 | regulation of focal adhesion assembly | ACVRL1, ARHGAP6, DAPK3, EFNA5, EPHA3, GPM6B, PTEN, PTK2, SLC9A1, SLK |
474 | GO:0007043 | 0.01 | 4.05 | 4.67 | 10 | 16 | cell-cell junction assembly | CD9, ACE, GJA4, GJB1, GJB2, JUP, LIM2, FSCN1, UGT8, CNTNAP1 |
475 | GO:0015991 | 0.00 | 4.05 | 7.02 | 15 | 24 | ATP hydrolysis coupled proton transport | ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP4A, ATP5G1, ATP5G2, ATP5G3, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, ATP6V0E1, ATP6V0D1 |
476 | GO:0030212 | 0.00 | 4.05 | 7.02 | 15 | 24 | hyaluronan metabolic process | CD44, CLTC, HAS1, HAS2, HAS3, HEXA, HEXB, HGF, ITIH1, ITIH2, ITIH4, MKI67, PIM1, SLC9A1, ABCC5 |
477 | GO:0005980 | 0.01 | 4.04 | 4.68 | 10 | 16 | glycogen catabolic process | CALM3, CPS1, G6PC, GAA, PHKA2, PHKB, PHKG1, PYGB, PYGM, STBD1 |
478 | GO:0006465 | 0.01 | 4.04 | 4.68 | 10 | 16 | signal peptide processing | BGLAP, CLN5, F2, F7, F10, PCSK5, PROC, PROS1, PROZ, SPCS2 |
479 | GO:0017144 | 0.01 | 4.04 | 4.68 | 10 | 16 | drug metabolic process | BCHE, CBR1, CYP1A2, CYP2A6, CYP3A4, DPEP1, FMO3, GUK1, PCK1, CYP4F2 |
480 | GO:0032026 | 0.01 | 4.04 | 4.68 | 10 | 16 | response to magnesium ion | C3, CD14, ENTPD6, KCNA1, KCNC2, KCNJ1, LIPC, SLC34A1, SNCA, FGF23 |
481 | GO:0043552 | 0.01 | 4.04 | 4.68 | 10 | 16 | positive regulation of phosphatidylinositol 3-kinase activity | EPHA8, PTK2B, FGFR3, FGR, FLT1, FLT3, KIT, PTK2, RAC1, CCL21 |
482 | GO:0048662 | 0.01 | 4.04 | 4.68 | 10 | 16 | negative regulation of smooth muscle cell proliferation | ANG, COMT, IFNG, IGFBP3, IL12B, ILK, VIP, VIPR2, KLF4, MFN2 |
483 | GO:0050927 | 0.01 | 4.04 | 4.68 | 10 | 16 | positive regulation of positive chemotaxis | S1PR1, F3, F7, ITGA2, KDR, SMAD3, NTRK3, VEGFA, VEGFB, SCG2 |
484 | GO:0071549 | 0.01 | 4.04 | 4.68 | 10 | 16 | cellular response to dexamethasone stimulus | AGTR2, AQP1, ARG1, ASS1, CASP9, CRH, DNMT3B, HMBS, SERPINF1, SRD5A1 |
485 | GO:0075733 | 0.01 | 4.04 | 4.68 | 10 | 16 | intracellular transport of virus | BST2, IFIT1, KPNA1, KPNA3, RAN, RPS27A, DYNLT1, TSG101, UBB, ALYREF |
486 | GO:0086091 | 0.01 | 4.04 | 4.68 | 10 | 16 | regulation of heart rate by cardiac conduction | JUP, KCNA5, KCNH2, KCNJ2, KCNQ1, SCN2B, SCN4B, SCN5A, HCN4, AKAP9 |
487 | GO:0097553 | 0.00 | 4.04 | 17.85 | 38 | 61 | calcium ion transmembrane import into cytosol | ABL1, ATP1A2, BAX, BDKRB1, CALM3, CASQ1, CASQ2, CYBA, DIAPH1, EDNRA, F2, F2R, PTK2B, XCR1, HRC, HTR2C, IL13, ITPR1, ITPR3, NTSR1, P2RX7, PDPK1, PLN, PRKCE, PRKD1, PTPN6, RYR1, RYR2, CCL21, XCL1, SLC8A1, SNCA, TRPC1, TRPM2, TRPV1, GSTO1, AKAP6, ATG5 |
488 | GO:0030029 | 0.00 | 4.03 | 6.05 | 13 | 21 | actin filament-based process | KCNA5, KCNH2, KCNQ1, SCN2B, SCN4B, SELE, SNTA1, TNNC2, TNNI2, TNNI3, TPM2, VIM, NUP155 |
489 | GO:0042509 | 0.00 | 4.00 | 10.83 | 23 | 37 | regulation of tyrosine phosphorylation of STAT protein | CD40, CSF1R, CSF2, CTF1, FGFR3, FLT3, FYN, HCLS1, HPX, IFNA2, IFNG, IGF1, IL3, IL12B, IL13, IL18, ISL1, KIT, PPP2R1A, PTPN2, TNFRSF1A, TNFRSF18, TNFSF18 |
490 | GO:0051437 | 0.00 | 4.00 | 16.97 | 36 | 58 | positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition | CCNB1, CDC20, CDC27, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, RPS27A, SKP1, UBB, UBE2D1, CUL1, CDC23, CDC16, PSMF1, PSME3, PSMD14 |
491 | GO:0048010 | 0.00 | 3.99 | 45.54 | 96 | 156 | vascular endothelial growth factor receptor signaling pathway | ACTB, ANGPT1, ARAF, AXL, BMPR2, CALM3, CAMK2A, CAMK2G, CSF2, CSF2RB, CTNNA1, CTNND1, CYBA, DUSP5, DUSP7, DUSP9, PTK2B, FGF3, FGF4, FGF6, FGF7, FGF8, FGFR3, FLT4, FYN, GRB2, GRIN2A, NRG1, HHEX, IL2RA, IL2RB, IL2RG, IL3, ITGAV, ITPR1, ITPR3, JUP, KIT, MARK3, KITLG, PDPK1, PPP5C, MAPK1, MAPK3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTK2, PTPRA, RAC1, RAF1, RASA2, RPS27A, SHB, SHC1, SPTA1, SPTB, UBB, VAV1, FGF23, FZD4, CUL3, PEA15, NRP2, NRP1, KL, PSMF1, NRG2, BCAR1, RAPGEF2, RBX1, PDCD6, AKAP9, RASA4, WASF2, PSME3, PSMD14 |
492 | GO:0008344 | 0.00 | 3.99 | 8.47 | 18 | 29 | adult locomotory behavior | APP, ARCN1, ATP1A2, ATP1A3, CLCN3, CNP, DNM1, GDNF, FOXA2, HOXD9, HOXD10, NTF4, NTSR1, PPT1, SNCA, TBCE, TSC1, PUM1 |
493 | GO:0071377 | 0.00 | 3.98 | 8.49 | 18 | 29 | cellular response to glucagon stimulus | ADCY1, ADCY7, ARG1, ASS1, CPS1, GCG, GCGR, GNAS, GNB2, GNG3, GNG10, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, GLP2R |
494 | GO:0051092 | 0.00 | 3.97 | 18.44 | 39 | 63 | positive regulation of NF-kappaB transcription factor activity | ADAM8, ALK, BTK, CAMK2A, CAT, CD40, CHUK, CLU, CTH, EDA, ICAM1, INS, IRAK1, IRAK2, LTF, PRKCB, PRKCI, PRKD1, PRKCQ, PSMA6, RPS3, RPS27A, S100A8, S100A9, S100A12, TRAF1, TRAF2, UBB, UBE2V1, TRIM25, IKBKG, TRADD, RIPK1, RIPK2, RPS6KA4, TNFSF18, ARHGEF2, RPS6KA5, CLOCK |
495 | GO:0008625 | 0.00 | 3.97 | 6.12 | 13 | 21 | extrinsic apoptotic signaling pathway via death domain receptors | BAD, BAX, CASP10, DDX3X, TNFRSF9, SORT1, TNFRSF1A, CRADD, TNFRSF18, TNFRSF10D, BAG3, KIAA0141, CASP8AP2 |
496 | GO:0031145 | 0.00 | 3.95 | 19.90 | 42 | 68 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | BUB1B, CCNB1, CDC20, CDC27, CDK2, MAD2L1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, RPS27A, SKP1, SKP2, UBB, UBE2D1, CUL1, CDC23, CDC16, BUB3, AURKB, PSMF1, PSME3, PSMD14 |
497 | GO:0048013 | 0.00 | 3.95 | 16.10 | 34 | 55 | ephrin receptor signaling pathway | ACTB, ADAM10, AP2B1, CHN1, AP2M1, AP2S1, DNM1, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EFNB2, EPHA2, EPHA3, EPHA4, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, FYN, RBPJ, LIMK1, NTRK3, PTK2, RAC1, ITSN1, ARHGEF7, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2 |
498 | GO:0009268 | 0.00 | 3.94 | 6.15 | 13 | 21 | response to pH | STS, CLCN7, CTSS, GJA3, GPLD1, INSRR, KCNJ8, PAM, PCK1, SERPINF1, SLC9A1, TRPV1, RAB11B |
499 | GO:0045907 | 0.00 | 3.94 | 6.15 | 13 | 21 | positive regulation of vasoconstriction | ADRA1B, AVPR1B, AVPR2, DBH, F2R, FGA, HRH1, ICAM1, OXTR, PTAFR, PTGS1, PTGS2, SHC1 |
500 | GO:0098900 | 0.00 | 3.94 | 6.15 | 13 | 21 | regulation of action potential | CAV3, CHRNB2, CNR1, CXADR, IFNG, JUP, KCNJ2, NTSR1, PTPN3, RYR2, SCN5A, SLC9A1, SUMO1 |
501 | GO:1904062 | 0.00 | 3.94 | 18.93 | 40 | 65 | regulation of cation transmembrane transport | ABL1, BAX, BDKRB1, BMP4, CACNB1, CACNB2, CACNB4, CASQ1, CTSS, CYBA, DIAPH1, DPP6, EDNRA, F2, F2R, PTK2B, HRC, IL13, KCNC2, KCNJ1, KCNJ2, KCNJ11, KCNS1, KCNS2, PDE4B, PDPK1, PRKD1, PTPN6, RYR2, S100A1, XCL1, SLC8A1, SNCA, TRPC1, KCNAB2, RGN, AKAP7, AKAP6, ATG5, AKAP9 |
502 | GO:0051283 | 0.00 | 3.93 | 17.56 | 37 | 60 | negative regulation of sequestering of calcium ion | ABL1, ATP1A2, BAX, BDKRB1, CALM3, CASQ1, CASQ2, CYBA, DIAPH1, EDNRA, F2, F2R, PTK2B, XCR1, HRC, HTR2C, IL13, ITPR1, ITPR3, NTSR1, P2RX7, PDPK1, PLN, PRKCE, PRKD1, PTPN6, RYR1, RYR2, CCL21, XCL1, SLC8A1, SNCA, TRPC1, TRPV1, GSTO1, AKAP6, ATG5 |
503 | GO:0007422 | 0.00 | 3.93 | 9.95 | 21 | 34 | peripheral nervous system development | ALDH3A2, ADGRB2, CDK5, EDNRB, EGR2, EGR3, ETV1, GDNF, GPC1, NRG1, HOXD9, HOXD10, ILK, ISL1, NTRK2, SERPINI1, SCN8A, SOX10, TBCE, UGT8, ONECUT2 |
504 | GO:0031295 | 0.00 | 3.93 | 9.95 | 21 | 34 | T cell costimulation | CD3D, CD3E, CD3G, CD4, CD5, CD28, CD86, CTLA4, DPP4, EFNB1, EFNB2, FYN, GRB2, PDPK1, PTPN6, RAC1, CCL21, TNFSF4, VAV1, TNFSF14, GRAP2 |
505 | GO:0002576 | 0.00 | 3.93 | 13.75 | 29 | 47 | platelet degranulation | ACTN4, ACTN1, ALB, APP, CALM3, CD9, CD36, CD63, CLU, FGA, HGF, HRG, IGF1, IGF2, KNG1, LAMP2, P2RX1, SERPINE1, PROS1, PSAP, SELP, SPARC, SYK, TUBA4A, VCL, VEGFA, VEGFB, WDR1, ABCC4 |
506 | GO:0007612 | 0.00 | 3.92 | 11.36 | 24 | 39 | learning | AMPH, ARF4, BCHE, COMT, CTNND2, FYN, JUN, NTRK2, NTSR1, PRKAR2B, PTGS1, PTGS2, PTN, SLC8A3, TACR2, CNTN2, VDAC1, FOSL1, AAAS, DGKI, GPR52, NRXN3, NRXN1, NRXN2 |
507 | GO:0097529 | 0.01 | 3.91 | 3.78 | 8 | 13 | myeloid leukocyte migration | CX3CR1, EDNRB, PTK2B, KIT, SFTPD, STAT5B, VEGFB, ARHGEF5 |
508 | GO:0070227 | 0.00 | 3.89 | 7.60 | 16 | 26 | lymphocyte apoptotic process | ADA, BMP4, BTK, CASP8, CD3G, CD74, CLC, DFFA, TSC22D3, IL2RA, PRKCQ, PTEN, RAG1, RIPK1, AURKB, BCL2L11 |
509 | GO:0030183 | 0.00 | 3.89 | 16.67 | 35 | 57 | B cell differentiation | ABL1, ADA, BAD, BAX, BCL3, PRDM1, BTK, CEBPG, CR2, EP300, PTK2B, HHEX, ONECUT1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, RBPJ, IL10, ITGA4, ITGB1, KIT, PTPN2, PTPN6, RAG1, RAG2, SP3, STAT5B, SYK, ADAM17, TPD52, FZD9, VPRBP |
510 | GO:0032418 | 0.00 | 3.88 | 7.61 | 16 | 26 | lysosome localization | FCER1A, FGR, IL13, IL13RA2, KIT, PDPK1, RAC2, S100A13, STXBP2, SYK, LAT2, VAMP8, SNAP23, CD84, GAB2, HDAC6 |
511 | GO:0001991 | 0.02 | 3.88 | 3.80 | 8 | 13 | regulation of systemic arterial blood pressure by circulatory renin-angiotensin | AGTR2, ANPEP, CTSG, ACE, ENPEP, F2R, PCSK5, ATP6AP2 |
512 | GO:0019098 | 0.02 | 3.88 | 3.80 | 8 | 13 | reproductive behavior | APLP2, APP, DBH, DRD5, GNAQ, HEXB, OXTR, PTEN |
513 | GO:0021854 | 0.02 | 3.88 | 3.80 | 8 | 13 | hypothalamus development | NR0B1, BAX, CRH, ETS1, SOX3, SRD5A1, UBB, NRP1 |
514 | GO:0030878 | 0.02 | 3.88 | 3.80 | 8 | 13 | thyroid gland development | FGF8, HHEX, SMAD3, MAPK1, MAPK3, RAF1, RAP1GAP, SRF |
515 | GO:0031954 | 0.02 | 3.88 | 3.80 | 8 | 13 | positive regulation of protein autophosphorylation | CALM3, ACE, INS, RAP2A, RAP2B, VEGFA, RASSF2, RAD50 |
516 | GO:0042346 | 0.02 | 3.88 | 3.80 | 8 | 13 | positive regulation of NF-kappaB import into nucleus | EDA, IL12B, IL18, PRKCQ, PTGS2, TRIP6, TNFSF14, IL18R1 |
517 | GO:0046457 | 0.02 | 3.88 | 3.80 | 8 | 13 | prostanoid biosynthetic process | ANXA1, CBR1, CD74, HPGD, PTGIS, PTGS1, PTGS2, AKR1C3 |
518 | GO:0046621 | 0.02 | 3.88 | 3.80 | 8 | 13 | negative regulation of organ growth | CAV3, CXADR, KCNK2, PTEN, PTK2, SLC6A4, TP73, CTDP1 |
519 | GO:0060351 | 0.02 | 3.88 | 3.80 | 8 | 13 | cartilage development involved in endochondral bone morphogenesis | COL1A1, COL2A1, COL9A1, COMP, RARA, RARB, SOX9, STC1 |
520 | GO:0071354 | 0.02 | 3.88 | 3.80 | 8 | 13 | cellular response to interleukin-6 | ENTPD2, FGA, PHB, PTGIS, PTPN2, SELPLG, STAT3, FGF23 |
521 | GO:0071480 | 0.02 | 3.88 | 3.80 | 8 | 13 | cellular response to gamma radiation | ATR, BCL2L1, CRYAB, CYBA, ELK1, RAD51, WRN, XRCC5 |
522 | GO:0071599 | 0.02 | 3.88 | 3.80 | 8 | 13 | otic vesicle development | COL2A1, FGF3, FGF8, GATA3, PROX1, SOX9, HESX1, NRP1 |
523 | GO:0090023 | 0.02 | 3.88 | 3.80 | 8 | 13 | positive regulation of neutrophil chemotaxis | CD74, EDNRA, CXCL2, CXCL3, RAC1, RAC2, CCL21, XCL1 |
524 | GO:0090077 | 0.02 | 3.88 | 3.80 | 8 | 13 | foam cell differentiation | ABCA1, AGTR1, ALOX15B, CD36, CRP, CSF2, ITGAV, NR1H2 |
525 | GO:0097009 | 0.02 | 3.88 | 3.80 | 8 | 13 | energy homeostasis | ACACB, AMPD2, CD36, PRCP, PRKAA1, STAT3, UBB, NR1D2 |
526 | GO:2000406 | 0.02 | 3.88 | 3.80 | 8 | 13 | positive regulation of T cell migration | ADAM8, ADAM10, ITGA4, S100A7, CCL21, XCL1, ADAM17, TNFSF14 |
527 | GO:0000186 | 0.00 | 3.87 | 39.80 | 83 | 136 | activation of MAPKK activity | ANGPT1, ARAF, BMP4, CALM3, CAMK2A, CAMK2G, CRKL, CSF2, CSF2RB, DUSP5, DUSP7, DUSP9, ERCC6, F2R, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FLT1, FYN, GRB2, RAPGEF1, GRIN2A, GRM1, NRG1, IL2RA, IL2RB, IL2RG, IL3, KIT, MARK3, KITLG, MAP3K11, PPP5C, MAPK1, MAPK3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTK2, PTPRA, RAF1, RAP1A, RASA2, RPS27A, SHC1, SPTA1, SPTB, UBB, FGF23, CUL3, PEA15, KL, PSMF1, NRG2, RAPGEF2, RBX1, AKAP9, RASA4, PSME3, PSMD14 |
528 | GO:0048545 | 0.00 | 3.87 | 13.65 | 29 | 48 | response to steroid hormone | ABCA2, ABCA3, ACADS, ALAD, ANXA3, BAX, BCHE, CALM3, CDKN1A, CDO1, CPS1, HNMT, IDH1, IL1RN, LCAT, LIPC, NTRK3, PTAFR, PTGS1, SDC1, SHC1, SLC9A3, SPARC, TAT, TRH, SCGB1A1, SLIT2, PTPRU, PDCD7 |
529 | GO:0000183 | 0.00 | 3.85 | 9.07 | 19 | 31 | chromatin silencing at rDNA | H3F3B, PHF2, TBP, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HIST1H3F, TAF1B, TAF1A |
530 | GO:0071398 | 0.00 | 3.85 | 9.07 | 19 | 31 | cellular response to fatty acid | ASS1, CCNB1, CPS1, CREB1, GNAS, FFAR3, HMGCS2, P2RY4, P2RY6, PDK4, PRKAA1, PRKCE, PTAFR, PTGDR, PTGER2, SREBF1, TNFSF4, AKR1C3, NR1H4 |
531 | GO:1901215 | 0.00 | 3.84 | 5.24 | 11 | 18 | negative regulation of neuron death | ATF4, CDK5, CREB1, IGF1, IL13, SERPINF1, PPP5C, SORL1, STAT3, TRAF2, IKBKG |
532 | GO:0007568 | 0.00 | 3.83 | 31.21 | 65 | 107 | aging | ABAT, ADA, APAF1, APOH, ARG1, ASS1, ATP2B1, ATP5G3, BAX, TSPO, CANX, CASP9, CAT, CD86, CLU, CNP, CNR1, CREB1, CRYAB, CTGF, CTNNA1, DCN, DLD, DNMT1, DNMT3A, EDNRA, EDNRB, F3, GHRHR, GSS, HMGCR, IGF1, IL10, IRAK1, JUN, JUND, KRT14, KRT16, KRT33B, KRT83, NTRK2, P2RY2, PAX2, SERPINF1, PENK, PRKCQ, PTGS1, RPS6KB1, RXRA, CX3CL1, SHC1, SNCA, SOD2, SREBF1, STAT3, TACR3, TNFRSF1B, TYMS, PRDM2, MADCAM1, SOCS3, RGN, AURKB, KL, LITAF |
533 | GO:0010595 | 0.00 | 3.82 | 10.54 | 22 | 36 | positive regulation of endothelial cell migration | ANGPT1, ANXA3, BMP4, BMPR2, SCARB1, ETS1, PTK2B, FLT4, GATA3, GPLD1, HSPB1, KDR, PRKD1, PROX1, PTGS2, SPARC, VEGFA, NRP2, NRP1, ITGB1BP1, BCAR1, PDCD6 |
534 | GO:0007292 | 0.00 | 3.82 | 5.26 | 11 | 18 | female gamete generation | FSHB, FSHR, HPGD, IL1R1, PGR, PTGS2, FOSL1, NRIP1, USP9X, DYNLL1, BMP15 |
535 | GO:0010332 | 0.00 | 3.82 | 5.26 | 11 | 18 | response to gamma radiation | BAX, BRCA2, ERCC6, GATA3, GPX1, MEN1, PRKAA1, TP73, XRCC2, TP63, SOCS3 |
536 | GO:0010165 | 0.00 | 3.81 | 5.27 | 11 | 18 | response to X-ray | ANXA1, BRCA2, CDKN1A, DNM2, ERCC6, GATA3, RAD51, TP73, XRCC2, XRCC5, TP63 |
537 | GO:0014808 | 0.00 | 3.81 | 5.27 | 11 | 18 | release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | ATP1A2, CALM3, CASQ1, CASQ2, HRC, PLN, RYR1, RYR2, SLC8A1, GSTO1, AKAP6 |
538 | GO:0021587 | 0.00 | 3.81 | 5.27 | 11 | 18 | cerebellum morphogenesis | ABL1, ABL2, ATP2B2, CACNA1A, CDK5, GRID2, PROX1, RFX4, WNT1, USP9X, NRXN1 |
539 | GO:0021846 | 0.00 | 3.81 | 5.27 | 11 | 18 | cell proliferation in forebrain | DCT, EMX2, FABP7, FGF8, HHEX, PCM1, RRM1, SIX3, TACC1, NUMB, ZEB2 |
540 | GO:0034105 | 0.00 | 3.81 | 5.27 | 11 | 18 | positive regulation of tissue remodeling | ADAM8, ATP6AP1, BAX, ERG, FSHB, B4GALT1, HRG, IL12B, IL18, SYK, VDR |
541 | GO:0035590 | 0.00 | 3.81 | 5.27 | 11 | 18 | purinergic nucleotide receptor signaling pathway | P2RX1, P2RX3, P2RX4, P2RX5, P2RX7, P2RY2, P2RY4, P2RY6, P2RY11, PTAFR, P2RY14 |
542 | GO:0044766 | 0.00 | 3.81 | 5.27 | 11 | 18 | multi-organism transport | BST2, EPS15, IFIT1, KPNA1, KPNA3, RAN, RPS27A, DYNLT1, TSG101, UBB, ALYREF |
543 | GO:0051898 | 0.00 | 3.81 | 5.27 | 11 | 18 | negative regulation of protein kinase B signaling | CRYBA1, DRD3, EPHA2, RAPGEF1, IGF1R, PTEN, PTPRJ, SFRP5, KLF4, SLC9A3R1, PDCD6 |
544 | GO:0070423 | 0.00 | 3.81 | 5.27 | 11 | 18 | nucleotide-binding oligomerization domain containing signaling pathway | BIRC3, XIAP, CASP8, CHUK, IRAK1, IRAK2, RPS27A, UBB, UBE2V1, IKBKG, RIPK2 |
545 | GO:0051279 | 0.00 | 3.79 | 6.71 | 14 | 23 | regulation of release of sequestered calcium ion into cytosol | ATP1A2, CASQ1, CASQ2, CYBA, DIAPH1, PTK2B, HRC, PLN, PRKCE, PRKD1, PTPN6, RYR2, SLC8A1, ATG5 |
546 | GO:0042063 | 0.00 | 3.79 | 20.64 | 43 | 71 | gliogenesis | ABL1, ABL2, ANXA1, ASCL1, BOK, CD9, CDK5, CDK6, CNP, VCAN, CSPG4, DTX1, LPAR1, EGR2, EIF2B1, GPC1, HEXB, NRG1, HMBS, IGF1, ILK, KCNJ10, NTRK2, PAX2, MAPK1, MAPK3, PTEN, PTPRJ, S100A8, S100A9, SLC8A3, SOX5, SOX9, STAT3, TAL1, TRPC4, VIM, VTN, LRP8, EIF2B3, EIF2B2, PHOX2B, PICK1 |
547 | GO:2000379 | 0.00 | 3.79 | 13.46 | 28 | 46 | positive regulation of reactive oxygen species metabolic process | AGTR1, AGTR2, ASS1, TSPO, CD36, CDKN1A, CLCN3, CLU, CRP, CYBA, DNM2, F2, PTK2B, GRB2, ICAM1, IFNG, INS, P2RX4, PTGS2, RAB27A, SNCA, TRPV1, OGT, AKR1C3, RIPK1, RGN, KLF4, RNF41 |
548 | GO:0051353 | 0.00 | 3.78 | 6.73 | 14 | 23 | positive regulation of oxidoreductase activity | ABL1, ABL2, AGTR1, AGTR2, CALM3, SCARB1, DHFR, PTK2B, FCER2, GDNF, IFNG, INS, SNCA, RGN |
549 | GO:0003091 | 0.00 | 3.77 | 6.73 | 14 | 23 | renal water homeostasis | ADCY1, ADCY7, AQP1, AVPR2, GNAS, HAS2, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, WFS1, CYP4F2 |
550 | GO:0071277 | 0.00 | 3.77 | 6.73 | 14 | 23 | cellular response to calcium ion | ADCY1, CRHBP, DPEP1, GPLD1, GUCA1A, JUN, JUNB, JUND, SCN5A, SYT1, AKR1C3, IQGAP1, RASA4, RASGRP2 |
551 | GO:0033209 | 0.00 | 3.76 | 23.66 | 49 | 81 | tumor necrosis factor-mediated signaling pathway | TNFRSF17, TNFRSF8, CD40, CD70, EDA, PTK2B, TNFRSF9, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, SKP1, ADAM17, TNFRSF1B, TNFSF4, NSMAF, CUL1, TNFSF14, TNFSF13, TNFSF12, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, TNFSF18, UBA3, PSMF1, BAG4, TNFSF15, PSME3, PSMD14 |
552 | GO:0002376 | 0.01 | 3.76 | 3.67 | 8 | 14 | immune system process | ADSS, CD5L, HP, INPPL1, ORM2, PTMS, SOX9, RUBCN |
553 | GO:1902041 | 0.00 | 3.76 | 8.19 | 17 | 28 | regulation of extrinsic apoptotic signaling pathway via death domain receptors | CASP8, FGA, GPX1, HGF, ICAM1, SERPINE1, RAF1, SP100, TRAF2, MADD, TRADD, RIPK1, TNFSF10, TNFRSF10B, TNFRSF10A, ARHGEF2, FEM1B |
554 | GO:0051592 | 0.00 | 3.74 | 11.09 | 23 | 38 | response to calcium ion | ANXA5, ANXA11, BAD, CALM3, CASQ2, ENTPD6, DUSP1, PTK2B, FGA, GDI1, ITPR3, LIPC, P2RX7, PENK, RYR2, SDC1, SPARC, TRPC1, TRPC3, SLC25A12, PDCD6, SLC25A13, KCNMB2 |
555 | GO:0009617 | 0.00 | 3.74 | 47.09 | 97 | 162 | response to bacterium | ABCA1, ABL1, ADH5, ALAD, ARG1, ASS1, ATP4B, AXL, BCR, BDKRB1, PRDM1, BYSL, TSPO, CASP8, CASP9, CD6, CD14, CD86, TNFRSF8, SCARB1, ENTPD2, CD40, CHUK, CNP, CNR1, COMT, CPS1, CSF2, CX3CR1, CYP1A2, CYP27B1, CD55, DCN, DNMT1, EDNRA, EDNRB, F2R, F3, GPX1, CXCL2, CXCL3, HMGCS2, ICAM1, IGF1, IL10RA, IL12RB2, IL13, TNFRSF9, IL18, IDO1, IRAK1, IRAK2, IRF5, JUN, JUNB, JUND, KCNJ8, NRF1, P2RY2, PDE4B, PENK, PF4V1, SERPINB9, PRKCE, MAPK1, MAPK3, PROS1, PTAFR, PTGER1, PTGER2, PTGS2, RARA, UPF1, RPS6KA3, RPS6KB1, CXCL5, SELE, SNCA, SPARC, STAT5B, TNFRSF1B, TNFSF4, SCGB1A1, VIL1, FZD5, OGT, PPM1D, PARG, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, SOCS3, LITAF, NR1D1, NR1H4, IL18BP |
556 | GO:0050852 | 0.00 | 3.72 | 28.68 | 59 | 98 | T cell receptor signaling pathway | ADA, CACNB4, CBLB, CD3D, CD3E, CD3G, CD4, CD28, CHUK, ELF1, FYB, FYN, GATA3, KCNN4, PDE4B, PDPK1, PRKCQ, MAPK1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTPN2, PTPN6, PTPRJ, RPS27A, SKP1, UBB, UBE2D1, UBE2D2, UBE2V1, WAS, CUL1, IKBKG, RIPK2, GRAP2, PSMF1, BCAR1, PSME3, PSMD14 |
557 | GO:0070372 | 0.04 | 3.69 | 2.89 | 6 | 10 | regulation of ERK1 and ERK2 cascade | EPHA2, EPHB1, PTPN6, RRAS, STYX, SYK |
558 | GO:0000302 | 0.00 | 3.68 | 8.71 | 18 | 30 | response to reactive oxygen species | ALDH3A2, BMP4, CDK2, DNM2, DPEP1, ERCC6, GPX2, IL1R1, KCNC2, PRDX1, PTPRN, S100A7, SOD2, SOD3, PRDX2, TRAF2, SCGB1A1, AKR1C3 |
559 | GO:0003018 | 0.04 | 3.68 | 2.90 | 6 | 10 | vascular process in circulatory system | ANGPT1, BCR, PTPRJ, TACR2, VEGFA, SLIT2 |
560 | GO:0008217 | 0.00 | 3.68 | 13.10 | 27 | 45 | regulation of blood pressure | ABAT, ACTA2, ACVRL1, ADH5, ATP1A1, ATP1A2, BDKRB1, CACNA1B, CNR1, CRH, CYP11B1, EDNRA, EDNRB, GCGR, FFAR3, GUCA2B, NRG1, ID2, P2RX1, P2RX4, PTAFR, PTGS1, PTGS2, RENBP, ACSM3, SGK1, TACR3 |
561 | GO:0002223 | 0.00 | 3.67 | 23.41 | 48 | 80 | stimulatory C-type lectin receptor signaling pathway | CALM3, CASP8, CHUK, EP300, FYN, ICAM2, ITPR1, ITPR3, PDPK1, PRKACB, PRKACG, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RAF1, RPS27A, SKP1, SYK, UBB, UBE2D1, UBE2D2, UBE2V1, CUL1, IKBKG, UBA3, RPS6KA5, PSMF1, PSME3, PSMD14 |
562 | GO:0060191 | 0.00 | 3.67 | 20.49 | 42 | 70 | regulation of lipase activity | ABL1, ABL2, ADCY1, ADCY7, ADCYAP1R1, ADRBK1, AGTR1, ANG, ANXA1, APOH, ARF4, ARHGAP6, ARL1, AVPR1B, BICD1, CALM3, CREB1, LPAR1, EDNRA, FGFR3, FLT1, GNA15, GNAQ, ITPR1, ITPR3, KIT, PDPK1, PPT1, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PTAFR, SORT1, SELE, SNCA, NR1H2, S1PR4, GPR55 |
563 | GO:0042542 | 0.00 | 3.66 | 10.21 | 21 | 35 | response to hydrogen peroxide | ADA, BAD, CAT, COL1A1, CRYAB, DUSP1, PTK2B, GJA3, GPX1, HBA1, HBA2, HP, JUN, KCNA5, KPNA4, OLR1, PPP2CB, SDC1, SHC1, SLC8A1, FOSL1 |
564 | GO:0007602 | 0.04 | 3.66 | 2.91 | 6 | 10 | phototransduction | GNAT2, GNGT2, RGR, TRPC3, UNC119, NR2E3 |
565 | GO:0071346 | 0.00 | 3.66 | 5.83 | 12 | 20 | cellular response to interferon-gamma | ASS1, CD58, DAPK3, EPRS, GAPDH, IL12B, CCL21, CCL22, CCL25, XCL1, CX3CL1, XCL2 |
566 | GO:0002275 | 0.04 | 3.65 | 2.91 | 6 | 10 | myeloid cell activation involved in immune response | ANXA3, BCR, PTAFR, SLAMF1, STXBP3, STX11 |
567 | GO:0019229 | 0.00 | 3.65 | 5.84 | 12 | 20 | regulation of vasoconstriction | AGTR1, ATP1A2, BMPR2, CHRM1, CHRM3, ACE, KCNA5, P2RX1, PRKCQ, CX3CL1, SNTA1, KCNMB2 |
568 | GO:0002028 | 0.01 | 3.65 | 4.38 | 9 | 15 | regulation of sodium ion transport | ATP1A1, P2RX4, P2RX7, PRSS8, SCNN1B, SGK1, SLC8A1, SLC9A3, SGK2 |
569 | GO:0032387 | 0.01 | 3.65 | 4.38 | 9 | 15 | negative regulation of intracellular transport | BST2, CRYAB, GDI1, IL13RA2, MAP1B, RAP1A, OGT, CD84, ITGB1BP1 |
570 | GO:1904427 | 0.04 | 3.65 | 2.92 | 6 | 10 | positive regulation of calcium ion transmembrane transport | BMP4, RYR2, S100A1, SLC9A1, SUMO1, RGN |
571 | GO:0033047 | 0.04 | 3.65 | 2.92 | 6 | 10 | regulation of mitotic sister chromatid segregation | CDC6, CENPE, PTEN, RB1, CUL3, DLGAP5 |
572 | GO:0017158 | 0.00 | 3.64 | 5.84 | 12 | 20 | regulation of calcium ion-dependent exocytosis | ARF1, CACNA1A, CDK5, B4GALT1, GLRA1, REST, SPINK1, STXBP3, SYT1, SYT4, ZP3, SYT7 |
573 | GO:0001776 | 0.04 | 3.64 | 2.92 | 6 | 10 | leukocyte homeostasis | ANXA1, FLT3, IFNG, KITLG, PDE4B, ADAM17 |
574 | GO:0050850 | 0.00 | 3.64 | 5.85 | 12 | 20 | positive regulation of calcium-mediated signaling | ADA, CALM3, CD3E, CD4, CD8A, FCER1A, ITGAL, P2RX3, P2RX4, P2RX5, SYK, GSTO1 |
575 | GO:0008542 | 0.00 | 3.64 | 8.78 | 18 | 30 | visual learning | ABL2, ADRA1B, APP, ATP1A2, ATP1A3, CDK5, CHRNB2, CREB1, CTNS, DBH, DRD3, GRIN2A, HMGCR, HRH1, ITGB1, KIT, PTPRZ1, SGK1 |
576 | GO:0061180 | 0.01 | 3.64 | 4.38 | 9 | 15 | mammary gland epithelium development | CAV3, CSF1R, ETV5, MGMT, PGR, PTCH1, SLC12A2, VDR, SLIT2 |
577 | GO:0048260 | 0.00 | 3.64 | 7.32 | 15 | 25 | positive regulation of receptor-mediated endocytosis | ANGPT1, BICD1, CAV3, CBL, CD63, HIP1, SERPINE1, PPT1, CCL21, SELE, SYK, VEGFA, VTN, SYNJ1, PICK1 |
578 | GO:0001945 | 0.04 | 3.64 | 2.92 | 6 | 10 | lymph vessel development | EFNB2, FLT4, KDR, PTPN14, SYK, VEGFA |
579 | GO:0006271 | 0.00 | 3.64 | 5.85 | 12 | 20 | DNA strand elongation involved in DNA replication | FEN1, PCNA, PRIM2, RFC1, RFC3, RFC4, RFC5, RPA2, RPA3, CDC45, GINS1, PARP3 |
580 | GO:0007628 | 0.00 | 3.64 | 5.85 | 12 | 20 | adult walking behavior | CACNA1A, CACNB4, CTNS, EPHA4, GLRA1, GLRB, KCNJ10, SCN1A, SCN8A, CNTN2, TRH, ZIC1 |
581 | GO:0022400 | 0.00 | 3.64 | 5.85 | 12 | 20 | regulation of rhodopsin mediated signaling pathway | CALM3, CNGA1, FNTA, GNAT1, GNGT1, GUCA1A, GUCY2F, GUCY2D, PRKCQ, RCVRN, RGS9, GUCA1C |
582 | GO:0045429 | 0.00 | 3.64 | 5.85 | 12 | 20 | positive regulation of nitric oxide biosynthetic process | AGTR2, ASS1, CLU, DNM2, PTK2B, ICAM1, IFNG, INS, P2RX4, PTGS2, TRPV1, KLF4 |
583 | GO:0051930 | 0.00 | 3.64 | 5.85 | 12 | 20 | regulation of sensory perception of pain | ACPP, COMT, EDNRB, F2R, GRIN2A, GRM1, IL10, NTSR1, P2RX3, PTAFR, SLC9A1, VIP |
584 | GO:0070266 | 0.00 | 3.64 | 5.85 | 12 | 20 | necroptotic process | SLC25A4, BIRC3, CASP8, RPS27A, TRAF2, UBB, TRADD, RIPK1, TNFSF10, TNFRSF10B, TNFRSF10A, ARHGEF2 |
585 | GO:0086002 | 0.00 | 3.64 | 5.85 | 12 | 20 | cardiac muscle cell action potential involved in contraction | CAV3, JUP, KCNA5, KCNH2, KCNJ2, KCNQ1, RYR2, SCN2B, SCN4B, SCN5A, SNTA1, NUP155 |
586 | GO:2001240 | 0.00 | 3.64 | 5.85 | 12 | 20 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | BCL2L1, COL2A1, CSF2, CTNNA1, CX3CR1, FYN, IFI6, GDNF, NRG1, IL1A, CX3CL1, RIPK1 |
587 | GO:0001964 | 0.04 | 3.64 | 2.92 | 6 | 10 | startle response | GLRA1, GLRB, GRIN2A, NRG1, KCNA1, PENK |
588 | GO:0031290 | 0.04 | 3.64 | 2.92 | 6 | 10 | retinal ganglion cell axon guidance | EFNA5, EPHB1, EPHB3, ISL1, NRCAM, RPL24 |
589 | GO:0072132 | 0.01 | 3.63 | 4.39 | 9 | 15 | mesenchyme morphogenesis | ACTA2, ACTG2, BMPR1A, FGF8, RBPJ, ISL1, SMAD3, SOX9, WNT11 |
590 | GO:0032870 | 0.00 | 3.63 | 10.06 | 21 | 36 | cellular response to hormone stimulus | ASNS, AVPR1B, AVPR2, BBS4, AKR1C4, DUSP1, GATA4, GATA6, JUN, JUNB, JUND, LIPC, OXTR, P2RY4, P2RY6, PRKCE, PTGDR, PTGER2, SLC34A1, TNFSF4, SLIT2 |
591 | GO:0001946 | 0.04 | 3.63 | 2.93 | 6 | 10 | lymphangiogenesis | ACVR2B, ACVRL1, BMPR2, FLT4, PROX1, PTPN14 |
592 | GO:0007625 | 0.04 | 3.63 | 2.93 | 6 | 10 | grooming behavior | APRT, CTNS, HPRT1, PPT1, DDO, NRXN1 |
593 | GO:0008356 | 0.04 | 3.63 | 2.93 | 6 | 10 | asymmetric cell division | ETV5, GOLGA2, ING2, SOX5, ACTR3, ACTR2 |
594 | GO:0016114 | 0.04 | 3.63 | 2.93 | 6 | 10 | terpenoid biosynthetic process | ALDH1A3, FDPS, RBP1, AKR1C3, GGPS1, DHRS9 |
595 | GO:0021516 | 0.04 | 3.63 | 2.93 | 6 | 10 | dorsal spinal cord development | ASCL1, PAX3, PROX1, RFX4, TAL1, WNT1 |
596 | GO:0021697 | 0.04 | 3.63 | 2.93 | 6 | 10 | cerebellar cortex formation | ATP2B2, CACNA1A, CDK5, GRID2, PROX1, NRXN1 |
597 | GO:0030049 | 0.04 | 3.63 | 2.93 | 6 | 10 | muscle filament sliding | TNNC2, TNNC1, TNNI2, TNNI3, TPM2, VIM |
598 | GO:0030252 | 0.04 | 3.63 | 2.93 | 6 | 10 | growth hormone secretion | GHRHR, GHSR, KISS1, RAB1A, LTBP4, ARHGEF7 |
599 | GO:0030826 | 0.04 | 3.63 | 2.93 | 6 | 10 | regulation of cGMP biosynthetic process | PTK2B, GUCA1A, GUCA2A, GUCA2B, RCVRN, GUCA1C |
600 | GO:0032332 | 0.04 | 3.63 | 2.93 | 6 | 10 | positive regulation of chondrocyte differentiation | ACVRL1, RUNX2, IHH, SMAD3, SOX5, SOX9 |
601 | GO:0033057 | 0.04 | 3.63 | 2.93 | 6 | 10 | multicellular organism reproductive behavior | DBH, DRD5, GNAQ, HEXB, OXTR, PTEN |
602 | GO:0034349 | 0.04 | 3.63 | 2.93 | 6 | 10 | glial cell apoptotic process | APAF1, BAX, CASP9, PRKCI, RB1, TRAF2 |
603 | GO:0040034 | 0.04 | 3.63 | 2.93 | 6 | 10 | regulation of development, heterochronic | ASCL1, FGF9, HMGN1, RBPJ, SOX5, NR2E1 |
604 | GO:0043568 | 0.04 | 3.63 | 2.93 | 6 | 10 | positive regulation of insulin-like growth factor receptor signaling pathway | GHRHR, GHSR, IGF1, IGFBP3, WNT1, IFT88 |
605 | GO:0045117 | 0.04 | 3.63 | 2.93 | 6 | 10 | azole transport | ADA, EDNRA, SLC22A3, SLC22A2, VAMP8, SNAP23 |
606 | GO:0045725 | 0.04 | 3.63 | 2.93 | 6 | 10 | positive regulation of glycogen biosynthetic process | IGF1, IGF2, INS, PTH, DYRK2, EPM2AIP1 |
607 | GO:0046885 | 0.04 | 3.63 | 2.93 | 6 | 10 | regulation of hormone biosynthetic process | ARNT, ATP1A1, CACNA1A, FFAR3, REST, AKR1C3 |
608 | GO:0048484 | 0.04 | 3.63 | 2.93 | 6 | 10 | enteric nervous system development | EDNRA, EDNRB, GDNF, RET, SOX10, PHOX2B |
609 | GO:0048486 | 0.04 | 3.63 | 2.93 | 6 | 10 | parasympathetic nervous system development | PHOX2A, EGR2, GDNF, SEMA3F, NRP1, PHOX2B |
610 | GO:0048643 | 0.04 | 3.63 | 2.93 | 6 | 10 | positive regulation of skeletal muscle tissue development | ARNTL, GPC1, HMGCR, PRKAA1, RPS6KB1, USP2 |
611 | GO:0060670 | 0.04 | 3.63 | 2.93 | 6 | 10 | branching involved in labyrinthine layer morphogenesis | GRB2, IL10, LLGL2, ST14, FZD5, SOCS3 |
612 | GO:0061298 | 0.04 | 3.63 | 2.93 | 6 | 10 | retina vasculature development in camera-type eye | ACVR2B, ACVRL1, BMPR2, FZD4, NRP1, SLC4A7 |
613 | GO:0070233 | 0.04 | 3.63 | 2.93 | 6 | 10 | negative regulation of T cell apoptotic process | ADA, BMP4, TSC22D3, IDO1, PRKCQ, RAG1 |
614 | GO:0070254 | 0.04 | 3.63 | 2.93 | 6 | 10 | mucus secretion | ADA, CYBA, P2RY2, PRKCE, VAMP8, ATG5 |
615 | GO:0070570 | 0.04 | 3.63 | 2.93 | 6 | 10 | regulation of neuron projection regeneration | EPHA4, HGF, NTRK3, PTEN, TNR, KLF4 |
616 | GO:0070633 | 0.04 | 3.63 | 2.93 | 6 | 10 | transepithelial transport | AQP1, CXADR, GPLD1, P2RY4, P2RY6, SLC12A2 |
617 | GO:0071732 | 0.04 | 3.63 | 2.93 | 6 | 10 | cellular response to nitric oxide | AQP1, CDK2, DNM2, DPEP1, KCNC2, TRAF2 |
618 | GO:0071872 | 0.04 | 3.63 | 2.93 | 6 | 10 | cellular response to epinephrine stimulus | KCNQ1, PDE4B, RYR2, SLC9A1, SNCA, SRD5A1 |
619 | GO:0072215 | 0.04 | 3.63 | 2.93 | 6 | 10 | regulation of metanephros development | AGTR2, BMP4, GDNF, PAX2, RET, SALL1 |
620 | GO:2001026 | 0.04 | 3.63 | 2.93 | 6 | 10 | regulation of endothelial cell chemotaxis | FGF4, HRG, HSPB1, KDR, PRKD1, VEGFA |
621 | GO:0008543 | 0.00 | 3.63 | 55.31 | 112 | 189 | fibroblast growth factor receptor signaling pathway | ADCY1, ADCY7, ADRBK1, ANGPT1, ARAF, BAD, CALM3, CAMK2A, CAMK2G, CASP9, RUNX2, CBL, CD28, CD86, CDKN1A, CHUK, CREB1, CSF2, CSF2RB, CTGF, DUSP5, DUSP7, DUSP9, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FYN, GATA3, GPC1, GRB2, GRIN2A, NRG1, NR4A1, IL2RA, IL2RB, IL2RG, IL3, ITPR1, ITPR3, KIT, MARK3, KITLG, FOXO4, OTX2, PDPK1, PPP2CB, PPP2R1A, PPP5C, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, MAPK1, MAPK3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, PTPRA, RAF1, RASA2, RPS6KB2, RPS27A, SHC1, SPTA1, SPTB, UBB, VAV1, SHOC2, FGF23, CUL3, PEA15, IQGAP1, KL, PSMF1, NRG2, RAPGEF2, CEP57, RBX1, FGFBP1, AKAP9, RASA4, PSME3, PSMD14, SPRY1 |
622 | GO:2000058 | 0.00 | 3.63 | 21.07 | 43 | 72 | regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process | CAV3, CCNB1, CDC20, CDC27, CLU, PTK2B, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, RPS27A, SKP1, SUMO3, UBB, UBE2D1, UBE3A, WNT1, CUL1, CDC23, CDC16, PSMF1, PSME3, PSMD14 |
623 | GO:0071774 | 0.00 | 3.60 | 60.00 | 121 | 205 | response to fibroblast growth factor | ADCY1, ADCY7, ADRBK1, ANGPT1, ARAF, BAD, CALM3, CAMK2A, CAMK2G, CASP9, RUNX2, CBL, CD28, CD86, CD44, CDKN1A, CHUK, COL1A1, CPS1, CREB1, CSF2, CSF2RB, CTGF, DUSP5, DUSP7, DUSP9, EGR3, ELK1, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FYN, GATA3, GPC1, GRB2, GRIN2A, NRG1, NR4A1, IL2RA, IL2RB, IL2RG, IL3, ITPR1, ITPR3, KIT, MARK3, KITLG, FOXO4, OTX2, PDPK1, PPP2CB, PPP2R1A, PPP5C, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, MAPK1, MAPK3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTH, PTK2, PTPRA, RAF1, RASA2, RPS6KB2, RPS27A, SHC1, SNCA, SPTA1, SPTB, UBB, SCGB1A1, VAV1, SHOC2, FGF23, CUL3, PEA15, IQGAP1, ITGB1BP1, KL, PSMF1, NRG2, RAPGEF2, CEP57, RBX1, FGFBP1, AKAP9, RASA4, PSME3, PSMD14, SPRY1 |
624 | GO:0051352 | 0.00 | 3.60 | 23.12 | 47 | 79 | negative regulation of ligase activity | ABL1, BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, DUSP1, LIMK1, MAD2L1, SMAD7, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS27A, TTK, UBB, UBE2D1, ZNF207, CDC23, CDC16, RGN, ZW10, BUB3, PSMF1, BAG5, PSME3, PSMD14 |
625 | GO:0014070 | 0.00 | 3.59 | 25.10 | 52 | 90 | response to organic cyclic compound | ACAT1, ADA, ADSS, ANGPT2, ASNS, ATP12A, BCL2L1, BSG, CD36, CHKA, COMT, DDX1, DHFR, DHODH, EDNRA, EDNRB, FGF8, KAT2A, HLCS, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, JUN, JUND, KCNC2, KCNJ8, MKI67, P2RX1, P2RX3, P2RX5, PPP2R2A, PRKAA1, PRKACB, PRKAR2B, PRKCE, PRKCQ, MAPK3, PSMB2, ABCD3, PYGM, SELL, SELP, TRPC3, PEA15, RIPK2, KYNU, DDX21, EIF4A3 |
626 | GO:0010646 | 0.00 | 3.58 | 21.82 | 46 | 82 | regulation of cell communication | ACTL6A, ARF1, ATP1A2, ATP2B2, ATP6V0A1, BCHE, TSPO, CDC20, CSNK2A2, CTSK, CXADR, DBN1, DRD5, EGR2, EIF4EBP2, KAT2A, GLRA1, GPM6B, GRIA1, HRH1, KCNJ10, RAB8A, PFN2, SEPT5, RAB3A, RAB5A, RARA, RPL28, RYR2, SLC6A4, SLC8A1, SRF, SYN1, VDAC1, ZBTB17, SLC30A1, LRP8, SYN3, RUVBL1, RAB33A, PICK1, RIN1, SNCAIP, FEZ2, RUBCN, RIMS3 |
627 | GO:0046427 | 0.00 | 3.58 | 12.29 | 25 | 42 | positive regulation of JAK-STAT cascade | CD40, CSF1R, CSF2, CTF1, F2R, PTK2B, FGFR3, FLT3, FYN, HCLS1, HPX, IFNA2, IFNG, IGF1, IL3, IL10, IL12B, IL13, IL18, ISL1, KIT, PRL, TNFRSF1A, TNFRSF18, TNFSF18 |
628 | GO:0044774 | 0.00 | 3.57 | 18.73 | 38 | 64 | mitotic DNA integrity checkpoint | CDK2, CDKN1A, FOXO4, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPA2, RPS27A, SETMAR, SOX4, TOP2A, TOP2B, TP73, UBB, TP63, CRADD, PSMF1, PSME3, PSMD14 |
629 | GO:1903035 | 0.00 | 3.57 | 9.33 | 19 | 32 | negative regulation of response to wounding | ABAT, ANXA5, APOH, EPHA4, F2, F12, FAP, FGA, GP1BA, HMGCR, HRG, KLKB1, KNG1, SERPINE1, PRKG1, PROS1, TNR, USF1, VTN |
630 | GO:0051336 | 0.00 | 3.56 | 13.64 | 28 | 48 | regulation of hydrolase activity | EFNA5, ENSA, EPHA3, EPHA4, EPHA5, EPHB3, MGMT, NTRK2, OAS1, OAS3, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PRKG1, PSMA3, PTK2, SET, SNRNP70, DYNLT1, TNNC1, TPM2, HSP90B1, TP63, CCPG1, ITGB1BP1, KIAA0141, NUAK1 |
631 | GO:0035265 | 0.00 | 3.55 | 15.78 | 32 | 54 | organ growth | ACACB, ACVR2B, ADRA1B, AGTR2, CCNB1, COL9A1, COMP, S1PR1, FGF7, FGF8, FGFR3, GATA4, GATA6, NRG1, IGF1, RBPJ, SMAD1, DDR2, PRKAR1A, PROX1, PSAP, RAG2, RARA, RARB, SOX9, STC1, UBE3A, COL14A1, SORBS2, LATS1, AKAP6, BCL2L11 |
632 | GO:0034097 | 0.00 | 3.55 | 10.66 | 22 | 38 | response to cytokine | ADAM10, AVPR2, BCL2L1, CCNE1, CD14, CYP27B1, GSS, FOXA2, ITIH4, JUN, JUNB, JUND, OXTR, PTGS2, RARA, RPS6KB1, SPARC, SRF, TYMS, SCGB1A1, FOSL1, KYNU |
633 | GO:0071156 | 0.00 | 3.54 | 20.78 | 42 | 71 | regulation of cell cycle arrest | BIN1, CDK2, CDK4, CDK5, CDKN1A, FAP, GATA6, ID2, FOXO4, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS27A, SETMAR, SOX4, TP73, UBB, RNF112, CRADD, PHOX2B, PSMF1, PSME3, PSMD14 |
634 | GO:0097191 | 0.01 | 3.53 | 4.90 | 10 | 17 | extrinsic apoptotic signaling pathway | ACVR1B, CD14, CD70, FGFR3, IFNG, SMAD3, P2RX7, PDPK1, TNFRSF1B, RNF41 |
635 | GO:0006482 | 0.00 | 3.53 | 7.90 | 16 | 27 | protein demethylation | HSF4, PHF2, KDM6A, UTY, KDM5C, KDM5D, HIST1H4I, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, KDM4A |
636 | GO:0001822 | 0.00 | 3.53 | 21.27 | 43 | 73 | kidney development | ACVR2B, AGTR1, ARG2, ASS1, BAX, CAT, CENPF, DCN, ACE, EDNRA, EFNB2, EPHA4, HAS2, HMGCS2, KCNJ1, KCNJ8, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, ODC1, OVOL1, PCSK5, SERPINF1, PRKX, PROX1, RARA, RARB, SDC1, SDC4, SLC12A1, SLC34A1, SOX4, SOX11, TP73, TSC1, UPK3A, WFS1, IFT88, SGPL1, RGN, BCL2L11 |
637 | GO:0034284 | 0.00 | 3.53 | 11.34 | 23 | 39 | response to monosaccharide | ACVR2B, ANGPT2, CAT, COL6A2, CTGF, EIF2B1, ENSA, PTK2B, GYS2, HMGCS2, ITGA2, PRKCQ, PTEN, PTGS2, RPS6KB1, SLC2A2, SLC8A1, SPARC, SREBF1, TRH, NR0B2, EIF2B3, EIF2B2 |
638 | GO:0048588 | 0.00 | 3.52 | 6.41 | 13 | 22 | developmental cell growth | AGTR2, APP, CAV3, DCC, EFNA5, GATA4, GDF9, SOX9, COL14A1, RND2, SORBS2, CTDP1, AKAP6 |
639 | GO:0007229 | 0.00 | 3.51 | 17.85 | 36 | 61 | integrin-mediated signaling pathway | ADAM10, DST, CD63, CTGF, CTNNA1, EMP2, PTK2B, FGR, FUT8, ILK, ITGA6, ITGA1, ITGA2, ITGA4, ITGA5, ITGA7, ITGA9, ITGAD, ITGAE, ITGAL, ITGAM, ITGAV, ITGB1, ITGB5, PRKD1, PTK2, SYK, TYROBP, VAV1, MADCAM1, CUL3, SEMA7A, ADAM15, ITGB1BP1, BCAR1, GAB2 |
640 | GO:0001709 | 0.00 | 3.50 | 6.44 | 13 | 22 | cell fate determination | ASCL1, BMP4, GATA3, GATA6, ISL1, NTF4, OTX2, PAX2, PROX1, PTCH1, WNT1, PTCH2, KLF4 |
641 | GO:0030431 | 0.00 | 3.50 | 6.44 | 13 | 22 | sleep | ADA, ALB, CHRNB2, CRH, DRD3, SLC29A1, GHRHR, GRIN2A, IL18, OXTR, PTGDR, SRD5A1, PER3 |
642 | GO:0035094 | 0.00 | 3.50 | 6.44 | 13 | 22 | response to nicotine | ABAT, ATP1A2, BAD, CHRNB2, CHRNB4, CNR1, CREB1, IGF1, IGF2, IL13, KCNJ11, PENK, SHC1 |
643 | GO:0007159 | 0.03 | 3.50 | 3.44 | 7 | 12 | leukocyte cell-cell adhesion | ITGA5, ITGB1, OLR1, SELE, SELP, SELPLG, MADCAM1 |
644 | GO:0007492 | 0.00 | 3.50 | 11.41 | 23 | 39 | endoderm development | BMPR1A, COL6A1, COL11A1, DUSP1, DUSP5, FGF8, GATA4, GATA6, HHEX, ONECUT1, HOXC11, HSBP1, ITGA4, ITGA5, ITGA7, ITGAV, ITGB5, LAMA3, SMAD3, OTX2, PAX9, VTN, EOMES |
645 | GO:0051238 | 0.00 | 3.47 | 21.95 | 44 | 75 | sequestering of metal ion | ABL1, ATP1A2, BAX, BDKRB1, CALM3, CASQ1, CASQ2, CYBA, DIAPH1, EDNRA, F2, F2R, PTK2B, XCR1, HRC, HTR2C, IL13, ITPR1, ITPR3, NTSR1, P2RX7, PDPK1, PLN, PRKCE, PRKD1, PTPN6, RYR1, RYR2, S100A7, S100A8, S100A9, CCL21, XCL1, SLC8A1, SNCA, HSP90B1, TRPC1, TRPV1, SLC30A1, SLC30A2, AP3D1, GSTO1, AKAP6, ATG5 |
646 | GO:0071622 | 0.01 | 3.47 | 4.97 | 10 | 17 | regulation of granulocyte chemotaxis | CD74, EDNRA, CXCL2, CXCL3, RAC1, RAC2, S100A7, CCL21, XCL1, SLIT2 |
647 | GO:0006693 | 0.01 | 3.46 | 4.98 | 10 | 17 | prostaglandin metabolic process | ACOX1, ANXA1, CBR1, CD74, HPGD, PTGIS, PTGS1, PTGS2, TNFRSF1A, AKR1C3 |
648 | GO:0014911 | 0.01 | 3.46 | 4.98 | 10 | 17 | positive regulation of smooth muscle cell migration | LPAR1, F3, HAS2, IGF1, ITGA2, P2RY2, P2RY6, RPS6KB1, VTN, NRP1 |
649 | GO:0021884 | 0.01 | 3.46 | 4.98 | 10 | 17 | forebrain neuron development | FGF8, GNAQ, OGDH, RAC1, RAC3, CNTN2, UBB, NRP1, SLIT2, RAPGEF2 |
650 | GO:0048016 | 0.01 | 3.46 | 4.98 | 10 | 17 | inositol phosphate-mediated signaling | RCAN1, NRG1, HRH1, IGF1, ITPR1, ITPR3, SLC9A1, SLC12A1, AKAP6, RCAN2 |
651 | GO:0048596 | 0.01 | 3.46 | 4.98 | 10 | 17 | embryonic camera-type eye morphogenesis | ALDH1A3, IHH, PAX2, PROX1, SIX3, SOX11, SP1, SP3, FZD5, ARID1A |
652 | GO:0060706 | 0.01 | 3.46 | 4.98 | 10 | 17 | cell differentiation involved in embryonic placenta development | ASCL2, PRDM1, CASP8, SNAI1, ST14, NR2F2, FZD5, EOMES, SOCS3, HAND1 |
653 | GO:0070670 | 0.01 | 3.46 | 4.98 | 10 | 17 | response to interleukin-4 | ALAD, ARG1, GATA3, IL2RG, IMPDH2, PTPN2, RPL3, XCL1, STAT5B, STAT6 |
654 | GO:1903053 | 0.01 | 3.46 | 4.98 | 10 | 17 | regulation of extracellular matrix organization | ABL1, ABL2, DPP4, ETS1, FAP, GPX1, SMAD3, DDR2, FSCN1, SOX9 |
655 | GO:2000516 | 0.01 | 3.46 | 4.98 | 10 | 17 | positive regulation of CD4-positive, alpha-beta T cell activation | ANXA1, CD86, CD55, IFNG, IL12B, PRKCQ, RARA, XCL1, TNFSF4, RIPK2 |
656 | GO:0007045 | 0.00 | 3.46 | 13.46 | 27 | 46 | cell-substrate adherens junction assembly | ACTN1, ACVRL1, ARHGAP6, DAPK3, EFNA5, CTTN, EPHA3, PTK2B, GPM6B, HRG, ITGA2, KDR, SMAD3, PDPK1, PTEN, PTK2, PTPRJ, RAC1, SDC4, SLC9A1, TRIP6, TSC1, VEGFA, ARHGEF7, ITGB1BP1, PPM1F, SLK |
657 | GO:0018108 | 0.00 | 3.45 | 21.38 | 43 | 74 | peptidyl-tyrosine phosphorylation | ALK, APLP2, APP, AXL, BCR, CLK1, CLK3, EPHA2, EPHA3, EPHA4, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, F2R, EFEMP1, FLT1, FLT4, HRG, IL12RB2, INSRR, MAP3K11, NTRK2, NTRK3, DDR2, PPP2R1A, PRKCE, PTPN2, PTPN6, RAP2B, RET, RYK, SHC1, SPINK1, TTK, TYRO3, DYRK2, STK16, DYRK4, BAZ1B, DYRK1B, ABI2 |
658 | GO:0051384 | 0.00 | 3.45 | 17.45 | 35 | 60 | response to glucocorticoid | ABCA3, ACADS, ALAD, ANXA3, BAD, BCHE, BGLAP, BMP4, C3, CDO1, CPS1, DUSP1, GHRHR, HNMT, IGF1, IL1RN, IL10, LCAT, LIPC, PAM, PTAFR, PTGS2, RPS6KB1, RXRA, SDC1, SHC1, SLC9A3, SPARC, TAT, TYMS, SCGB1A1, SOCS3, SLIT2, PTPRU, PDCD7 |
659 | GO:0015844 | 0.00 | 3.45 | 8.47 | 17 | 29 | monoamine transport | ABAT, ADRBK1, AGTR2, CHRNB2, CNR1, DRD3, GDNF, FFAR3, OXTR, PCP4, PTGS1, RAB3B, SLC6A2, SLC22A1, SLC22A3, SLC22A2, PICK1 |
660 | GO:0051046 | 0.00 | 3.44 | 12.87 | 26 | 45 | regulation of secretion | AGTR1, CAMK2A, CD40, CHRNB4, CRP, GDF9, B4GALT1, KCNQ1, LLGL2, NTRK2, PAM, PDPK1, PFN2, RAB3B, RAC2, RALA, SGK1, SPINK1, STC1, STXBP2, SYN1, TRAF2, SLC9A3R1, SNCAIP, RIMS2, RIMS3 |
661 | GO:0031638 | 0.00 | 3.44 | 15.49 | 31 | 53 | zymogen activation | APAF1, BAD, BAX, BOK, CASP8, CASP9, CD14, COL4A3, CTSH, F2R, F3, HIP1, IFI16, SMAD3, P2RX1, RET, S100A8, S100A9, SNCA, TRAF2, TRADD, RIPK1, CRADD, TNFSF10, TNFRSF10B, TNFRSF10A, EIF2AK3, TNFSF15, CASP8AP2, PDCD6, BCL2L11 |
662 | GO:0034340 | 0.00 | 3.43 | 12.00 | 24 | 41 | response to type I interferon | ADAR, BST2, IFI6, UBE2K, IFIT1, IFIT3, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IRF1, IRF5, ISG20, OAS1, OAS3, PTPN2, PTPN6, SHMT2, SP100, STAT2, TYK2, OASL, SOCS3 |
663 | GO:0070509 | 0.00 | 3.43 | 6.97 | 14 | 24 | calcium ion import | ATP2A1, CACNB2, CDK5, XCR1, HTR2C, ITPR1, ITPR3, P2RX7, RYR1, CCL21, SLC8A3, TRPC4, TRPM2, TRPV1 |
664 | GO:0090279 | 0.03 | 3.42 | 3.49 | 7 | 12 | regulation of calcium ion import | CAV3, CRH, GCG, SPINK1, STC1, SLC30A1, ZP3 |
665 | GO:0048011 | 0.00 | 3.41 | 69.07 | 136 | 236 | neurotrophin TRK receptor signaling pathway | ADCY1, ADCY7, ADCYAP1R1, ADRBK1, AP2B1, AGTR2, ANGPT1, ARAF, ARHGAP4, BAD, CALM3, CAMK2A, CAMK2G, CASP9, CD28, CD86, CDKN1A, CHUK, AP2M1, AP2S1, CREB1, CRKL, CSF2, CSF2RB, DUSP5, DUSP7, DUSP9, ELK1, FGD1, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FYN, GRB2, RAPGEF1, GRIN2A, NRG1, NR4A1, IL2RA, IL2RB, IL2RG, IL3, IRAK1, ITPR1, ITPR3, KIT, MARK3, KITLG, FOXO4, NTRK2, PCSK5, PDPK1, PPP2R5D, PPP5C, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRKCI, MAPK1, MAPK3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, PTPRA, RAC1, RAF1, RALA, RAP1A, RASA2, RIT1, RPS6KA1, RPS6KA2, RPS6KA3, RPS6KB2, RPS27A, SORT1, ITSN1, SHC1, SOS2, SPTA1, SPTB, STAT3, ADAM17, TRIO, UBB, VAV1, FGF23, CUL3, PEA15, RIPK2, ARHGEF7, ARHGEF1, ARHGEF2, RPS6KA5, KL, PSMF1, NRG2, BCAR1, RAPGEF2, ARHGEF11, RBX1, BCL2L11, AKAP9, RASA4, PSME3, PSMD14, SPRY1 |
666 | GO:0070076 | 0.03 | 3.40 | 3.50 | 7 | 12 | histone lysine demethylation | HSF4, PHF2, KDM6A, UTY, KDM5C, KDM5D, KDM4A |
667 | GO:0048678 | 0.03 | 3.40 | 3.50 | 7 | 12 | response to axon injury | ARF4, ARG1, BAX, DPYSL3, FGFR3, KCNK2, RANGAP1 |
668 | GO:0035249 | 0.03 | 3.40 | 3.51 | 7 | 12 | synaptic transmission, glutamatergic | CACNA1A, CACNB4, CDH8, CDK5, CLCN3, GRID2, P2RX1 |
669 | GO:0010596 | 0.00 | 3.40 | 7.02 | 14 | 24 | negative regulation of endothelial cell migration | ACVRL1, AGTR2, ANGPT2, APOH, KRIT1, DCN, HRG, SERPINF1, SP100, STC1, NR2F2, ITGB1BP1, KLF4, SLIT2 |
670 | GO:0033198 | 0.00 | 3.40 | 7.02 | 14 | 24 | response to ATP | KCNJ11, P2RX1, P2RX3, P2RX4, P2RX5, P2RX7, P2RY11, PTEN, PTGS2, SELL, SLC8A1, HSP90B1, TRPC3, TRPV1 |
671 | GO:1902743 | 0.00 | 3.40 | 7.02 | 14 | 24 | regulation of lamellipodium organization | AQP1, DNM2, EPHA2, HRG, RAC1, RAC2, FSCN1, CLRN1, VIL1, WNT1, ARHGEF7, SLIT2, ARPC2, WASF2 |
672 | GO:0014014 | 0.03 | 3.40 | 3.51 | 7 | 12 | negative regulation of gliogenesis | BMP4, DRD3, F2, FGFR3, ID2, NTRK3, NR2E1 |
673 | GO:0002026 | 0.03 | 3.39 | 3.51 | 7 | 12 | regulation of the force of heart contraction | ADRA1B, ADRBK1, ATP1A1, ATP1A2, GAA, IFNG, PLN |
674 | GO:0045730 | 0.03 | 3.39 | 3.51 | 7 | 12 | respiratory burst | CD52, CYBA, CD55, PGAM1, PRKCQ, RAC1, RAC2 |
675 | GO:0071470 | 0.03 | 3.39 | 3.51 | 7 | 12 | cellular response to osmotic stress | TSPO, DDX3X, SERPINB6, SCN2A, SLC2A4, ARHGEF2, OXSR1 |
676 | GO:0003071 | 0.03 | 3.39 | 3.51 | 7 | 12 | renal system process involved in regulation of systemic arterial blood pressure | AGTR1, AGTR2, CYBA, EMP2, F2R, PCSK5, CYP4F2 |
677 | GO:0006337 | 0.03 | 3.39 | 3.51 | 7 | 12 | nucleosome disassembly | HMGA1, SET, SMARCA4, SMARCC1, SMARCD3, SMARCE1, ARID1A |
678 | GO:0006972 | 0.03 | 3.39 | 3.51 | 7 | 12 | hyperosmotic response | AQP1, HNMT, PDPK1, RAC1, SLC12A1, TACR3, ARHGEF2 |
679 | GO:0007250 | 0.03 | 3.39 | 3.51 | 7 | 12 | activation of NF-kappaB-inducing kinase activity | IRAK1, TRAF2, IKBKG, TNFRSF10B, TNFRSF10A, TRAF4, TNFSF15 |
680 | GO:0007271 | 0.03 | 3.39 | 3.51 | 7 | 12 | synaptic transmission, cholinergic | CACNA1A, CHRM1, CHRM3, CHRNB2, CHRNB4, IFNG, TACR2 |
681 | GO:0014059 | 0.03 | 3.39 | 3.51 | 7 | 12 | regulation of dopamine secretion | ABAT, CHRNB2, CNR1, DRD3, GDNF, PCP4, SNCA |
682 | GO:0019430 | 0.03 | 3.39 | 3.51 | 7 | 12 | removal of superoxide radicals | CD36, DHFR, PRDX1, SOD2, SOD3, PRDX2, RGN |
683 | GO:0030224 | 0.03 | 3.39 | 3.51 | 7 | 12 | monocyte differentiation | BMP4, CSF1R, IFI16, JUN, SP3, VEGFA, PIR |
684 | GO:0032731 | 0.03 | 3.39 | 3.51 | 7 | 12 | positive regulation of interleukin-1 beta production | CASP5, HSPB1, IFI16, IFNG, ISL1, SMAD3, P2RX7 |
685 | GO:0032967 | 0.03 | 3.39 | 3.51 | 7 | 12 | positive regulation of collagen biosynthetic process | BMP4, CTGF, F2, F2R, IHH, ITGA2, SERPINB7 |
686 | GO:0035116 | 0.03 | 3.39 | 3.51 | 7 | 12 | embryonic hindlimb morphogenesis | ALX3, BMP4, FGF4, FGF8, GPC3, GNAS, RARB |
687 | GO:0044253 | 0.03 | 3.39 | 3.51 | 7 | 12 | positive regulation of multicellular organismal metabolic process | BMP4, CTGF, F2, F2R, IHH, ITGA2, SERPINB7 |
688 | GO:0045648 | 0.03 | 3.39 | 3.51 | 7 | 12 | positive regulation of erythrocyte differentiation | ACVR1B, ARNT, ETS1, PRMT1, ID2, TAL1, ZNF16 |
689 | GO:0046174 | 0.03 | 3.39 | 3.51 | 7 | 12 | polyol catabolic process | GK2, GPD2, INPP1, NTSR1, PTEN, SORD, SYNJ1 |
690 | GO:0048070 | 0.03 | 3.39 | 3.51 | 7 | 12 | regulation of developmental pigmentation | BAX, GNAQ, IHH, KIT, KITLG, ZEB2, BCL2L11 |
691 | GO:0048713 | 0.03 | 3.39 | 3.51 | 7 | 12 | regulation of oligodendrocyte differentiation | BMP4, DRD3, ID2, RHEB, TP73, WDR1, OLIG2 |
692 | GO:0048853 | 0.03 | 3.39 | 3.51 | 7 | 12 | forebrain morphogenesis | FGF8, HHEX, OTX1, OTX2, PTEN, IFT88, HESX1 |
693 | GO:0052312 | 0.03 | 3.39 | 3.51 | 7 | 12 | modulation of transcription in other organism involved in symbiotic interaction | EP300, HPN, JUN, NTRK3, REST, SMARCA4, SP1 |
694 | GO:0061213 | 0.03 | 3.39 | 3.51 | 7 | 12 | positive regulation of mesonephros development | AGTR2, GATA3, GDNF, PAX2, SALL1, SOX9, VEGFA |
695 | GO:0071380 | 0.03 | 3.39 | 3.51 | 7 | 12 | cellular response to prostaglandin E stimulus | GNAS, P2RY4, P2RY6, PRKAA1, PRKCE, PTGER2, TNFSF4 |
696 | GO:0086064 | 0.03 | 3.39 | 3.51 | 7 | 12 | cell communication by electrical coupling involved in cardiac conduction | ATP1A1, ATP1A2, ATP1A3, CALM3, HRC, RYR2, SLC8A1 |
697 | GO:1901623 | 0.03 | 3.39 | 3.51 | 7 | 12 | regulation of lymphocyte chemotaxis | ADAM10, PTK2B, S100A7, XCL1, ADAM17, TNFSF14, CXCL14 |
698 | GO:1902259 | 0.03 | 3.39 | 3.51 | 7 | 12 | regulation of delayed rectifier potassium channel activity | KCNQ1, KCNS1, KCNS2, SUMO1, KCNAB1, AKAP7, AKAP6 |
699 | GO:0071363 | 0.00 | 3.38 | 83.80 | 165 | 292 | cellular response to growth factor stimulus | ACVR2B, ADCY1, ADCY7, ADCYAP1R1, ADRBK1, AP2B1, ANGPT1, ANGPT2, ARAF, ARHGAP4, BAD, BGLAP, BMP1, BMP3, BMP8B, BYSL, CALM3, CAMK2A, CAMK2G, CASP9, CAT, CD28, CD86, CD44, CDKN1A, CHUK, AP2M1, AP2S1, CLU, COL2A1, CPS1, CRKL, CSF2, CSF2RB, CTGF, DLX5, DUSP5, DUSP7, DUSP9, EGR3, ELK1, EMD, ETV2, FGD1, FGF3, FGF6, FGF7, FGF8, FGFR3, FLT3, FLT4, GAS1, GRB2, GRIN2A, NRG1, NR4A1, HSPB1, IL2RA, IL2RB, IL2RG, IL3, IRAK1, ITPR1, ITPR3, KCND3, KDR, KIT, MARK3, KITLG, FOXO4, NTRK3, PAX9, PCSK5, PPP2CB, PPP2R1A, PPP2R5D, PPP5C, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRKCI, PRKD1, MAPK1, MAPK3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTPRA, RAC1, RAF1, RALA, RAP1GAP, RASA2, RIT1, RPS6KA1, RPS6KA2, RPS6KA3, RPS6KB1, RPS6KB2, RYR2, ITSN1, SHC1, SNCA, SOS2, SPARC, SPTA1, SPTB, SRD5A1, STAT3, T, TNFRSF1B, TRIO, VAV1, LRP8, SHOC2, FGF23, CUL3, PEA15, RIPK1, RIPK2, NRP2, ARHGEF7, PHOX2B, ARHGEF1, ARHGEF2, BMP15, RPS6KA5, ITGB1BP1, KLF4, KL, PSMF1, NRG2, CEP57, ZFYVE16, ARHGEF11, RBX1, BCL2L11, AKAP9, RASA4, PSME3, PSMD14 |
700 | GO:0007173 | 0.00 | 3.38 | 58.42 | 115 | 200 | epidermal growth factor receptor signaling pathway | ABL1, ABL2, ADAM10, ADCY1, ADCY7, ADRBK1, ANGPT1, APLP2, APP, ARAF, ARF4, BAD, CALM3, CAMK2A, CAMK2G, CAMLG, CASP9, CD28, CD86, CDKN1A, CHUK, CREB1, CSF2, CSF2RB, DUSP5, DUSP7, DUSP9, PTK2B, EFEMP1, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FYN, GRB7, GRIN2A, NRG1, NR4A1, IL2RA, IL2RB, IL2RG, IL3, ITPR1, ITPR3, KIT, MARK3, KITLG, FOXO4, PDPK1, PIK3C2A, PPP5C, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, MAPK1, MAPK3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, PTPRA, RAF1, RASA2, RPS6KB2, SHC1, SOX9, SPTA1, SPTB, ADAM17, VAV1, VIL1, FGF23, CUL3, PEA15, IQGAP1, REPS2, RPS6KA5, KL, PSMF1, NRG2, BCAR1, RAPGEF2, RASSF2, RBX1, AKAP9, RASA4, PSME3, PSMD14 |
701 | GO:0007548 | 0.00 | 3.38 | 16.58 | 33 | 57 | sex differentiation | ACVR1B, ADCYAP1R1, AHR, ANG, AXL, BMP4, BRCA2, CAPN5, CCNE1, CHAT, FANCF, FANCG, FGF7, CENPI, GDF9, IDH1, KDR, PGR, PTPRN, SALL1, TSPY1, TYRO3, UBE3A, VEGFA, ZP3, NRIP1, FZD4, TP63, EIF2B2, CDKL2, BMP15, SLIT2, IRX5 |
702 | GO:1903779 | 0.00 | 3.38 | 12.58 | 25 | 43 | regulation of cardiac conduction | ATP1A1, ATP1A2, ATP1A3, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, CALM3, CASQ1, CASQ2, CXADR, HRC, ITPR1, ITPR3, KCNJ11, FXYD3, PLN, RYR1, RYR2, SLC8A1, SLC8A3, TNNI3, TRPC1, ABCC9 |
703 | GO:0010810 | 0.01 | 3.38 | 5.51 | 11 | 19 | regulation of cell-substrate adhesion | DAPK3, EFNA5, EPHA3, GPM6B, ONECUT1, ATXN3, PTK2, RAC2, SLC9A1, ONECUT2, SLK |
704 | GO:0014823 | 0.00 | 3.36 | 9.07 | 18 | 31 | response to activity | ALAD, ANGPT2, BGLAP, CAT, CREB1, DNMT1, DNMT3B, IGF1, IL10, ITGA2, ITGB1, OXCT1, PCK1, PRKAA1, PTN, RYR2, SRD5A1, UQCRC1 |
705 | GO:0048771 | 0.00 | 3.36 | 13.09 | 26 | 45 | tissue remodeling | ANXA1, ARG1, BGLAP, CAPN1, TPP1, CSF1R, CSPG4, CTSK, S1PR1, EPHA2, ELF3, F2R, PTK2B, IAPP, IHH, IL1A, LIPA, P2RX7, PDK4, PTH, RAC1, RAC2, SLC34A1, INPP4B, GPR55, RASSF2 |
706 | GO:0010243 | 0.00 | 3.35 | 28.30 | 57 | 102 | response to organonitrogen compound | ADSS, AGTR2, ANXA1, STS, ATP4B, AVPR1B, AVPR2, BSG, TSPO, CAT, CCNE1, CDKN1A, CYC1, DHFR, DUSP1, EGR2, EIF2B1, F7, FLT3, GNAI1, HADHA, HLCS, IL10, INPPL1, IRAK1, IRF5, JUN, JUNB, JUND, LTA4H, P2RX1, P2RX3, P2RX5, P2RX7, PCK1, PLN, PTEN, PTGS1, PTPRN, PYGM, QDPR, RBBP4, SORT1, SDC1, SELL, SLC2A2, SPARC, STXBP3, TP73, TRPC3, TYR, FOSL1, EIF2B3, EIF2B2, KYNU, RNF40, EPM2AIP1 |
707 | GO:0043401 | 0.00 | 3.35 | 26.34 | 52 | 90 | steroid hormone mediated signaling pathway | NR0B1, ARNTL, BMP4, CCNE1, CRY2, DDX5, EP300, ESRRG, NR5A2, GHRHR, NR4A1, HNF4G, IGF1, ISL1, SCGB2A1, CNOT2, PGR, PHB, PPP5C, RAN, RARA, RARB, RB1, RNF6, RXRA, RXRG, SGK1, SKP2, SMARCA4, TAF7, NR2F1, NR2F2, NR2E1, NR2C1, NR2C2, UBE3A, NR1H2, VDR, YWHAH, NRIP1, ARID1A, NR0B2, BUD31, TRIP4, NR1D1, CLOCK, RNF14, NR1I3, NR1H4, NR1D2, NR2E3, HDAC6 |
708 | GO:0001890 | 0.00 | 3.35 | 18.70 | 37 | 64 | placenta development | ADA, ANG, ARNT, ASCL2, PRDM1, BMPR2, BSG, CASP8, CCNF, CDX2, CSF2, CYP27B1, DCN, EPOR, ETV2, GHSR, GJB2, GRB2, IL10, ITGA4, MEN1, SERPINE1, PTGIS, PTGS2, PTK2, RXRA, SLC8A1, SNAI1, SP1, SP3, ST14, STC1, VDR, EOMES, HAND1, CUL7, TRIM28 |
709 | GO:0060070 | 0.00 | 3.34 | 11.59 | 23 | 40 | canonical Wnt signaling pathway | BCL9, CTNND2, EMD, FGF8, GATA3, GATA4, MGAT3, PPP1CA, PTEN, RAB5A, RYK, RYR2, SDC1, T, TBL1X, KDM6A, FZD3, FZD4, FZD7, FZD8, FZD9, KLF4, PTPRU |
710 | GO:0006836 | 0.00 | 3.34 | 7.56 | 15 | 26 | neurotransmitter transport | ATP1A2, DRD3, GDNF, GFAP, GPM6B, KCNJ10, RAB3B, SLC6A4, SLC6A6, SLC6A7, SLC6A8, SLC22A1, SLC22A3, SLC6A5, SV2B |
711 | GO:0000578 | 0.01 | 3.33 | 5.56 | 11 | 19 | embryonic axis specification | FOXA2, HOXD8, SMAD6, OTX2, PTCH1, STIL, T, KDM6A, WNT1, FZD5, FRAT1 |
712 | GO:0002704 | 0.01 | 3.33 | 5.56 | 11 | 19 | negative regulation of leukocyte mediated immunity | BCR, BST2, CR1, IFNA2, IGF2, IL13RA2, SERPINB9, PTPN6, SERPINB4, XCL1, CD84 |
713 | GO:0010092 | 0.01 | 3.33 | 5.56 | 11 | 19 | specification of organ identity | BMP4, FGF3, FGF8, GDNF, HOXC11, RBPJ, ISL1, PAX2, PAX3, SMARCD3, SPRY1 |
714 | GO:0030501 | 0.01 | 3.33 | 5.56 | 11 | 19 | positive regulation of bone mineralization | ACVR2B, BMP4, BMPR1A, BMPR2, GPM6B, LTF, SMAD3, P2RX7, PTH, SLC8A1, KL |
715 | GO:0042462 | 0.01 | 3.33 | 5.56 | 11 | 19 | eye photoreceptor cell development | BBS4, PRDM1, GNAT1, GNAT2, GNGT1, NTRK2, PRKCI, RPGR, TULP1, VEGFA, NR2E3 |
716 | GO:0045773 | 0.01 | 3.33 | 5.56 | 11 | 19 | positive regulation of axon extension | BMPR2, GOLGA4, NRG1, ILK, LIMK1, MAP1B, NTRK3, SRF, VEGFA, SEMA7A, NRP1 |
717 | GO:0045824 | 0.01 | 3.33 | 5.56 | 11 | 19 | negative regulation of innate immune response | ADAR, CR1, IFI16, IGF2, INS, SERPINB9, PTPN2, RPS19, SERPINB4, TYRO3, NR1H2 |
718 | GO:0048873 | 0.01 | 3.33 | 5.56 | 11 | 19 | homeostasis of number of cells within a tissue | ADD1, BAX, CD7, F2R, FLT3, LIPA, P2RX7, RAC1, RAC3, SOX9, COL14A1 |
719 | GO:0055010 | 0.01 | 3.33 | 5.56 | 11 | 19 | ventricular cardiac muscle tissue morphogenesis | COL11A1, NRG1, RBPJ, ISL1, SMAD7, PROX1, RXRA, RYR2, TNNC1, TNNI3, HAND1 |
720 | GO:1903959 | 0.01 | 3.33 | 5.56 | 11 | 19 | regulation of anion transmembrane transport | CLCN2, CLCN3, CLCN6, CLCN7, CLCNKA, CLCNKB, PTAFR, SLC34A1, VDAC1, VDAC2, RIPK1 |
721 | GO:2000352 | 0.01 | 3.33 | 5.56 | 11 | 19 | negative regulation of endothelial cell apoptotic process | ABL1, ABL2, ANGPT1, KRIT1, FGA, GATA3, ICAM1, IL13, KDR, SERPINE1, SCG2 |
722 | GO:0070374 | 0.00 | 3.33 | 24.88 | 49 | 85 | positive regulation of ERK1 and ERK2 cascade | ABL1, ABL2, ANGPT1, ATP6AP1, BMP4, C3, CD36, CD44, CD74, CCR1, CSF1R, CTGF, EDNRA, EPOR, F2R, PTK2B, FGA, FGF4, FGF8, FGFR3, FLT4, FSHR, GCG, HMGCR, HTR2C, ICAM1, IL1A, JUN, KDR, PHB, MAPK3, PTEN, RAP1A, S100A7, CCL21, CCL22, CCL25, XCL1, CX3CL1, SLAMF1, XCL2, VEGFA, VEGFB, FGF23, SEMA7A, RIPK2, NRP1, GPR55, RAPGEF2 |
723 | GO:0044275 | 0.00 | 3.33 | 13.17 | 26 | 45 | cellular carbohydrate catabolic process | ADRA1B, ARNT, BPGM, CALM3, CPS1, G6PC, GAA, GK2, GPD2, IGF1, INS, P2RX7, PGAM1, PHKA2, PHKB, PHKG1, PPP1CA, PRKAA1, PRKAG1, PYGB, PYGM, SORD, STAT3, OGT, MGAM, STBD1 |
724 | GO:0071345 | 0.00 | 3.33 | 6.48 | 13 | 23 | cellular response to cytokine stimulus | ALAD, ARG1, CD86, DPYSL3, ETV3, HCLS1, HMBS, IL13, IMPDH2, ITGA4, MAPK1, RPL3, AKAP6 |
725 | GO:0002768 | 0.00 | 3.33 | 26.77 | 53 | 93 | immune response-regulating cell surface receptor signaling pathway | ANGPT1, ARAF, BAD, CAMK2A, CAMK2G, CASP9, CD86, CD40, CDKN1A, CREB1, CSF2, CSF2RB, DUSP5, DUSP7, DUSP9, FCER1A, FCGRT, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, GRIN2A, NRG1, NR4A1, IL2RA, IL2RB, IL2RG, IL3, JUN, KIT, MARK3, KITLG, FOXO4, PPP5C, PTPRA, RASA2, RPS6KB2, SHC1, SPTA1, SPTB, FGF23, CUL3, PEA15, KL, NRG2, RAPGEF2, GAB2, RBX1, AKAP9, RASA4 |
726 | GO:0031644 | 0.00 | 3.32 | 7.60 | 15 | 26 | regulation of neurological system process | ACPP, COMT, EDNRB, F2R, GLRA1, GRIN2A, GRM1, HTR2C, IFNG, IL10, NTSR1, PTEN, SLC9A1, VIP, EIF2AK3 |
727 | GO:0009791 | 0.00 | 3.32 | 17.27 | 34 | 59 | post-embryonic development | ACVR2B, ATRX, BAX, PRDM1, BMP4, CLPS, CYP1A2, DHCR7, EMX1, FBN1, EFEMP1, FLT3, GATA3, GNAQ, GNAS, HMGN1, IGF2R, INPPL1, ITPR1, KCNJ1, KDR, LLGL2, RAB3A, SEPP1, SLC8A1, TBCE, TP73, VEGFA, FZD5, USP9X, DLK1, SGPL1, KLF4, BCL2L11 |
728 | GO:0016259 | 0.00 | 3.32 | 17.27 | 34 | 59 | selenocysteine metabolic process | FAU, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, RPL14, RPL23, EIF4A3 |
729 | GO:0031281 | 0.00 | 3.31 | 7.60 | 15 | 26 | positive regulation of cyclase activity | ADCYAP1R1, AVPR2, CALM3, DRD5, EDNRA, FSHR, GHRHR, GNAS, NTRK2, P2RY11, MAPK3, RAF1, VIP, VIPR2, WFS1 |
730 | GO:0021762 | 0.00 | 3.31 | 7.61 | 15 | 26 | substantia nigra development | ACTB, ATP5F1, ATP5J, CALM3, CASP5, CNP, COX6B1, FGF9, FGFR3, GLUD1, S100A1, YWHAH, ZNF148, DYNLL1, SYNGR3 |
731 | GO:0034113 | 0.00 | 3.31 | 7.61 | 15 | 26 | heterotypic cell-cell adhesion | CD44, CD58, CXADR, FGA, IL1RN, ITGA4, ITGA5, ITGA7, ITGAD, ITGAV, ITGB1, JUP, NRCAM, MADCAM1, KLF4 |
732 | GO:0044786 | 0.00 | 3.31 | 7.61 | 15 | 26 | cell cycle DNA replication | ATRX, FEN1, PCNA, PRIM2, UPF1, RFC1, RFC3, RFC4, RFC5, RPA2, RPA3, SMC1A, CDC45, SMC3, GINS1 |
733 | GO:0048146 | 0.00 | 3.31 | 7.61 | 15 | 26 | positive regulation of fibroblast proliferation | AQP1, BMI1, CCNB1, CD74, CDC6, CDK4, CDK6, CDKN1A, FBLN1, IGF1, IL13, JUN, DDR2, PTPRZ1, WNT1 |
734 | GO:0060395 | 0.00 | 3.31 | 7.61 | 15 | 26 | SMAD protein signal transduction | BMP1, BMP3, BMP4, BMP8B, GATA4, GDF9, INHA, JUN, SMAD1, SMAD3, SMAD9, T, VIM, BMP15, GDF15 |
735 | GO:0051270 | 0.00 | 3.31 | 6.51 | 13 | 23 | regulation of cellular component movement | ATP1A1, ATP1A2, GATA4, B4GALT1, JUP, KCNJ2, PDE4B, PLN, RYR2, SCN5A, TNNC1, SUMO1, DNAH11 |
736 | GO:0031329 | 0.02 | 3.30 | 4.03 | 8 | 14 | regulation of cellular catabolic process | APAF1, BPGM, SCARB1, IDH1, PGAM1, PPP1CA, PRKAG1, OGT |
737 | GO:0050731 | 0.00 | 3.29 | 28.10 | 55 | 96 | positive regulation of peptidyl-tyrosine phosphorylation | ABL1, ANGPT1, CD3E, CD4, CD36, CD40, CD44, CD74, CSF1R, CSF2, CSPG4, CTF1, ACE, EFNA1, EFNA5, ERCC6, PTK2B, FCER1A, FGF7, FGFR3, FLT3, FYN, HCLS1, HGF, NRG1, HPX, ICAM1, IFNA2, IFNG, IGF1, IGF2, IL3, IL12B, IL13, IL18, INS, ISL1, ITGA5, ITGB1, KIT, KITLG, PTPRZ1, SYK, ADAM17, TNFRSF1A, VEGFA, VEGFB, VTN, LRP8, RIPK2, TNFRSF18, NRP1, TNFSF18, UNC119, ARHGEF2 |
738 | GO:0090263 | 0.00 | 3.29 | 24.00 | 47 | 82 | positive regulation of canonical Wnt signaling pathway | XIAP, ARNTL, COL1A1, CSNK1D, DAPK3, DLX5, EDA, FGF9, FGFR3, FZD2, RBPJ, ILK, JUP, SMAD3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS27A, SOX4, UBB, WNT1, FZD5, TNKS, PSMF1, USP34, FRAT1, PSME3, PSMD14 |
739 | GO:0010959 | 0.00 | 3.29 | 39.90 | 78 | 137 | regulation of metal ion transport | ABL1, ADCYAP1R1, ATF4, ATP2B2, BAX, BDKRB1, BMP4, TSPO, CACNA1B, CACNB1, CACNB2, CACNB4, CALM3, CAMK2A, CAMK2G, CASQ1, CASQ2, CD4, CD63, CCR1, CRH, CYBA, DIAPH1, DPP6, EDNRA, F2, F2R, PTK2B, GCG, FFAR1, HRC, ICAM1, IGF1, IL13, KCNA5, KCNC2, KCNH2, KCNJ1, KCNJ2, KCNQ1, KCNS1, KCNS2, NTSR1, P2RX1, P2RX3, P2RX5, PDE4B, PDPK1, PIK3C2A, PLN, PRKD1, PTGS2, PTPN6, RCVRN, RYR2, S100A1, XCL1, SNCA, SPINK1, STC1, TRPC1, TRPC3, TRPC4, SUMO1, VIP, WFS1, SLC30A1, ZP3, KCNAB1, KCNAB2, CD84, RGN, GSTO1, AKAP7, AKAP6, ATG5, OXSR1, AKAP9 |
740 | GO:2000134 | 0.00 | 3.28 | 19.90 | 39 | 68 | negative regulation of G1/S transition of mitotic cell cycle | CDK2, CDKN1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, RB1, RPA2, RPS27A, SMARCA4, SOX4, TP73, UBB, TP63, CRADD, PSMF1, CTDSP2, PSME3, PSMD14, CTDSPL |
741 | GO:0009755 | 0.01 | 3.28 | 6.09 | 12 | 21 | hormone-mediated signaling pathway | ASIP, CRH, CRHBP, FSHR, GCGR, GHSR, PRCP, PTH, PTPN2, STAT5B, TRH, LATS1 |
742 | GO:0007265 | 0.00 | 3.28 | 51.90 | 101 | 178 | Ras protein signal transduction | ANGPT1, ARAF, CALM3, CAMK2A, CAMK2G, CDK2, CDKN1A, CRKL, CSF2, CSF2RB, DNM2, DOK1, DUSP5, DUSP7, DUSP9, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FYN, GDI1, GRB2, RAPGEF1, GRIN2A, IL2RA, IL2RB, IL2RG, IL3, KIT, MARK3, PPP2CB, PPP5C, MAPK1, MAPK3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTK2, PTPRA, RALA, RAP1A, RAP2A, RAP2B, RASA2, RB1, RIT1, RPS27A, RRAS, RSU1, SHC1, SPTA1, SPTB, UBB, FGF23, OGT, MADD, PEA15, DOK2, USP8, CYTH2, KL, GRAP2, PSMF1, NRG2, AATK, RALGPS1, RAPGEF2, DENND4B, MFN2, RBX1, AKAP9, G3BP1, ABI2, RASA4, WASF2, PSME3, PSMD14, RASGRP2, SPRY1 |
743 | GO:0071560 | 0.01 | 3.27 | 6.10 | 12 | 21 | cellular response to transforming growth factor beta stimulus | APAF1, ARG1, COL1A1, CX3CR1, DNMT1, FYN, PENK, XCL1, SOX5, SOX9, CLEC3B, STK16 |
744 | GO:0001525 | 0.00 | 3.27 | 32.20 | 63 | 111 | angiogenesis | ADAM8, ANG, ANGPT1, ANPEP, BMP4, KLF5, CASP8, COL15A1, CSPG4, CTGF, TYMP, S1PR1, EFNA1, EFNB2, EGR3, EPHA2, ELK3, EMP2, ENPEP, EPHB1, EPHB2, EPHB3, FAP, FGF6, FGF9, FLT4, GPI, GPLD1, NR4A1, ID1, RBPJ, IL18, ITGAV, ITGB1, JUN, MEOX2, MFGE8, NRCAM, PRKX, PTEN, PTK2, S100A7, SAT1, SHB, SHC1, SP100, SRPK2, SYK, TAL1, TNFAIP2, VEZF1, FZD5, SCG2, FZD8, ADAM15, NRP2, SLIT2, NRXN3, NRXN1, HAND1, EIF2AK3, SLC12A6, WASF2 |
745 | GO:0042493 | 0.00 | 3.26 | 68.77 | 133 | 235 | response to drug | ABAT, ABCA1, ABCA2, ABCA3, ADA, ADCY1, ADCYAP1R1, ADD3, ALAD, ANXA1, AQP1, ARG1, ASS1, ATP1A1, ATP1A3, ATP4A, ATR, BAD, BAX, BCHE, BGLAP, TSPO, CAT, CCNB1, CCNE1, CD86, CD69, CDH1, CDK2, CDK4, CDKN1A, CENPF, CHAT, CHUK, COL1A1, COMT, CPS1, CREB1, CRH, CRHBP, CYBA, CYP1A2, CYP2A6, CYP3A4, DAD1, DHODH, DNMT1, DNMT3A, DNMT3B, DPEP1, DRD3, EMX1, EMX2, PTK2B, FGF8, FYN, GABRA4, GAD1, GATA3, GATA4, GATA6, GNAS, GPLD1, GRIN2A, HADHA, HMBS, HMGCS2, HTR2C, ICAM1, IFNG, IGF2, IL10, ITGA2, ITGB1, JUN, JUNB, JUND, KCNH2, KCNJ11, KCNK3, KCNQ1, LIPC, MGMT, OXCT1, OXTR, P2RX7, PAM, PDE4B, PFAS, ABCB1, PRKAR2B, PTCH1, PTEN, PTH, PTGS2, PTN, ABCD3, QDPR, RAD51, RAP1A, RAP2A, REST, RET, RPS6KB1, SLC6A4, SLC8A1, SLC9A1, SLC34A1, SLC22A1, SLC22A3, SLC22A2, SLC22A5, SMPD1, SNCA, SORD, SRD5A1, SREBF1, SRP14, STAT3, ADAM17, TOP1, TP73, TYMS, SCGB1A1, UQCRFS1, VEGFB, LRP8, FOSL1, BCAR3, SOCS3, EFTUD2, ATG5, PPM1F |
746 | GO:0090132 | 0.00 | 3.26 | 40.09 | 78 | 137 | epithelium migration | ACVRL1, AGTR2, ANGPT1, ANGPT2, ANXA3, APOH, AQP1, BMP4, BMPR2, KRIT1, SCARB1, CD63, CTSH, DCN, DPP4, EFNA1, EFNB2, EGR3, EPHA2, EMP2, ETS1, PTK2B, FAP, FGF4, FGF7, FGF8, FLT4, GATA3, GPLD1, GPX1, HAS2, NR4A1, HRG, HSPB1, ID1, IFNG, ITGA2, ITGB1, JUN, KDR, KIT, KRT2, KRT16, PDPK1, SERPINF1, PFN2, PRCP, PRKCE, PRKD1, PRKX, PROX1, PTEN, PTGS2, PTK2, PTPRR, S100A2, S100P, SOX9, SP100, SPARC, SRF, STC1, NR2F2, NR2E1, VEGFA, VIL1, SCG2, TNFSF12, NRP2, NRP1, ITGB1BP1, KLF4, SLIT2, BCAR1, PPM1F, ZEB2, HDAC6, PDCD6 |
747 | GO:0045807 | 0.03 | 3.25 | 4.07 | 8 | 14 | positive regulation of endocytosis | ACTN4, ARF1, AXL, CD14, GPC3, ITGB1, SNCA, TSG101 |
748 | GO:0002824 | 0.00 | 3.24 | 12.29 | 24 | 42 | positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | ADA, ANXA1, C3, CD4, CD28, CD40, FCER1A, FCER2, HPX, IFNG, IL12B, P2RX7, PRKCQ, PVR, XCL1, STAT6, TRAF2, TNFSF4, UNG, ZP3, FZD5, TNFSF13, RIPK2, IL27RA |
749 | GO:0006073 | 0.01 | 3.24 | 6.13 | 12 | 21 | cellular glucan metabolic process | ADRA1B, CALM3, CPS1, G6PC, GAA, GCGR, PHKA2, PHKB, PYGB, PYGM, MGAM, STBD1 |
750 | GO:0002067 | 0.03 | 3.24 | 4.09 | 8 | 14 | glandular epithelial cell differentiation | ASCL1, FGF8, GATA6, IL13, MEN1, PROX1, RXRA, TP63 |
751 | GO:0046148 | 0.01 | 3.24 | 6.14 | 12 | 21 | pigment biosynthetic process | ADA, ALAD, ALAS2, APRT, TSPO, COX15, CPOX, HMBS, HPRT1, SHMT1, UROS, AP3D1 |
752 | GO:0006283 | 0.00 | 3.24 | 10.24 | 20 | 35 | transcription-coupled nucleotide-excision repair | DDB1, EP300, ERCC3, ERCC4, ERCC6, HMGN1, PCNA, RFC1, RFC3, RFC4, RFC5, RPA2, RPA3, RPS27A, UBB, XPA, CUL4A, COPS3, COPS2, RBX1 |
753 | GO:0045761 | 0.00 | 3.24 | 10.24 | 20 | 35 | regulation of adenylate cyclase activity | ADCYAP1R1, AVPR2, CALM3, DRD3, DRD5, EDNRA, EDNRB, FSHR, GALR1, GHRHR, GNAI3, GNAS, NTRK2, P2RY11, PALM, RAF1, VIP, VIPR2, WFS1, GABBR2 |
754 | GO:0072676 | 0.00 | 3.24 | 10.24 | 20 | 35 | lymphocyte migration | ADAM8, ADAM10, ECM1, S1PR1, PTK2B, GATA3, GPR15, ITGA4, RET, S100A7, CCL21, CCL22, CCL25, XCL1, CX3CL1, STK10, XCL2, ADAM17, TNFSF14, CXCL14 |
755 | GO:0001990 | 0.01 | 3.24 | 6.14 | 12 | 21 | regulation of systemic arterial blood pressure by hormone | AGTR1, AGTR2, ANPEP, CTSG, CYBA, ACE, DRD3, ENPEP, F2R, PCSK5, RPS6KA2, ATP6AP2 |
756 | GO:0023051 | 0.00 | 3.24 | 14.83 | 30 | 56 | regulation of signaling | ARF1, BCHE, CAMLG, CDC20, DBN1, DRD5, EGR2, EIF4EBP2, GLRA1, GPM6B, GRIA1, HRH1, KCNJ10, RAB8A, PFN2, SEPT5, RAB3A, RAB5A, RARA, SLC6A4, SRF, SYN1, SLC30A1, LRP8, SYN3, RAB11B, PICK1, RIN1, SNCAIP, RIMS3 |
757 | GO:0046928 | 0.03 | 3.24 | 4.09 | 8 | 14 | regulation of neurotransmitter secretion | CACNA1A, CAMK2A, CHRNB4, NTRK2, SNCA, TACR2, SLC30A1, SNCAIP |
758 | GO:0007190 | 0.01 | 3.23 | 6.15 | 12 | 21 | activation of adenylate cyclase activity | ADCYAP1R1, AVPR2, CALM3, DRD5, EDNRA, FSHR, GHRHR, GNAS, NTRK2, P2RY11, RAF1, VIPR2 |
759 | GO:0035987 | 0.01 | 3.23 | 6.15 | 12 | 21 | endodermal cell differentiation | COL6A1, COL11A1, GATA6, HSBP1, ITGA4, ITGA5, ITGA7, ITGAV, ITGB5, LAMA3, VTN, EOMES |
760 | GO:0043470 | 0.01 | 3.23 | 6.15 | 12 | 21 | regulation of carbohydrate catabolic process | ADRA1B, ARNT, BPGM, IGF1, INS, P2RX7, PGAM1, PPP1CA, PRKAA1, PRKAG1, STAT3, OGT |
761 | GO:0060338 | 0.01 | 3.23 | 6.15 | 12 | 21 | regulation of type I interferon-mediated signaling pathway | ADAR, UBE2K, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, PTPN2, PTPN6, STAT2, TYK2, SOCS3 |
762 | GO:0001569 | 0.03 | 3.23 | 4.10 | 8 | 14 | patterning of blood vessels | BAX, EDNRA, FGF8, IHH, SRF, VEGFA, NRP1, SEMA3E |
763 | GO:0010656 | 0.03 | 3.23 | 4.10 | 8 | 14 | negative regulation of muscle cell apoptotic process | APOH, PTK2B, NRG1, HMGCR, IGF1, ILK, PDPK1, BAG3 |
764 | GO:0015874 | 0.03 | 3.23 | 4.10 | 8 | 14 | norepinephrine transport | AGTR2, CRH, FFAR3, OXTR, PTGS1, SLC6A2, SLC22A1, SNCA |
765 | GO:0032753 | 0.03 | 3.23 | 4.10 | 8 | 14 | positive regulation of interleukin-4 production | CD3E, CD86, GATA3, PRG2, PRKCQ, RARA, TNFSF4, ZP3 |
766 | GO:0035162 | 0.03 | 3.23 | 4.10 | 8 | 14 | embryonic hemopoiesis | FLT3LG, GATA3, IL3, KDR, KIT, KITLG, TAL1, VEGFA |
767 | GO:0035235 | 0.03 | 3.23 | 4.10 | 8 | 14 | ionotropic glutamate receptor signaling pathway | APP, ATP1A3, PTK2B, GRIA1, GRIA4, GRID1, GRID2, GRIN2A |
768 | GO:0042133 | 0.03 | 3.23 | 4.10 | 8 | 14 | neurotransmitter metabolic process | ABAT, DAGLA, CACNA1A, CHAT, COMT, GAD1, PAH, SLC22A2 |
769 | GO:0050729 | 0.00 | 3.22 | 16.97 | 33 | 58 | positive regulation of inflammatory response | ADAM8, AGTR1, C3, CD6, CD28, CNR1, CTSS, EDNRA, F12, FCER1A, FFAR3, IL12B, IL18, IDO1, ITGA2, KLKB1, SERPINE1, PTGS2, RPS19, S100A8, S100A9, S100A12, XCL1, CX3CL1, STAT5B, XCL2, TNFRSF1A, TNFSF4, ZP3, VAMP8, TNFSF18, IL1RL1, CLOCK |
770 | GO:1902107 | 0.00 | 3.21 | 12.84 | 25 | 44 | positive regulation of leukocyte differentiation | ADA, ADAM8, ANXA1, AXL, BAD, PRDM1, BTK, CD86, CD74, EGR3, FLT3LG, GATA3, IHH, IL2RA, RAG1, RARA, STAT5B, SYK, TNFSF4, AP3B1, TNFSF9, RIPK2, IL1RL2, VNN1, AP3D1 |
771 | GO:0030900 | 0.00 | 3.21 | 15.87 | 31 | 55 | forebrain development | NR0B1, APAF1, APLP2, APP, ATRX, BMPR1A, CDH1, CHRNB2, CNP, CREB1, CRH, ETS1, FGFR3, FYN, GHRHR, RBPJ, ISL1, KCNC2, PCDH9, PRKG1, PTN, STIL, SLC6A4, SOX3, NR2F2, TOP2B, ARID1A, OGT, CHRD, DCLK1, OLIG2 |
772 | GO:1903039 | 0.00 | 3.20 | 31.02 | 60 | 106 | positive regulation of leukocyte cell-cell adhesion | ADA, ADAM8, ANXA1, BAD, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD28, CD86, CD44, CD59, CD74, CTLA4, CD55, DHPS, DPP4, EFNB1, EFNB2, EGR3, FLOT2, FYN, GATA3, GRB2, HAS2, IFNG, IGF1, IGF2, IHH, IL2RA, IL12B, IL18, ITGA4, ITGAL, PDPK1, PRKCQ, PTAFR, PTPN6, RAC1, RAG1, RARA, CCL21, XCL1, SPTA1, STAT5B, SYK, TRAF2, TNFSF4, VAV1, ZP3, AP3B1, TNFSF14, TNFSF9, RIPK2, IL1RL2, VNN1, AP3D1, GRAP2 |
773 | GO:0001824 | 0.00 | 3.20 | 12.88 | 25 | 44 | blastocyst development | ADA, BRCA2, BYSL, CDX2, DAD1, DMBT1, ELF3, ETV2, IGF1, JUNB, CNOT2, PSMC3, PSMC4, RAD51B, RBBP8, SP1, SP3, SRF, ZP3, EOMES, CUL3, LATS1, HAND1, GINS1, MFN2 |
774 | GO:0051897 | 0.00 | 3.20 | 12.88 | 25 | 44 | positive regulation of protein kinase B signaling | ADAM8, ANGPT1, AXL, CD28, F3, F7, F10, GATA3, GPX1, HCLS1, NRG1, IGF1, IGF1R, IGF2, ILK, INS, PTK2, PTPRJ, CCL21, ITSN1, VEGFB, ZP3, AKR1C3, ITGB1BP1, BAG4 |
775 | GO:0007411 | 0.00 | 3.20 | 89.45 | 171 | 307 | axon guidance | ABL1, ABL2, ACTB, ADAM10, AP2B1, ANGPT1, APBB2, APP, ARAF, BMPR2, CACNB1, CACNB2, CACNB4, CALM3, CAMK2A, CAMK2G, CD72, AP2M1, AP2S1, COL2A1, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2, CSF2RB, CSNK2A1, CSNK2A2, DCC, DLG3, DLX5, DNM1, DPYSL3, DUSP5, DUSP7, DUSP9, EFNA1, EFNA3, EFNA4, EFNB1, EFNB2, EPHA2, EPHA3, EPHA5, EPHA8, ETV1, FGF3, FGF4, FGF6, FGF7, FGF9, FGFR3, FYN, GATA3, GDNF, GFRA1, GPC1, GRB2, GRIN2A, NRG1, IL2RA, IL2RB, IL2RG, IL3, ITGA1, ITGA2, ITGA5, ITGA9, ITGAV, ITGB1, KIF5A, KIT, LIMK1, MARK3, KITLG, NTN3, OPHN1, OTX2, PPP5C, PRKCQ, MAPK1, MAPK3, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTK2, PTPRA, RAC1, RAC2, RAF1, RASA2, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RRAS, SCN5A, ITSN1, SHC1, SIAH2, SOS2, SPTA1, SPTB, CNTN2, TNR, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, SEMA3B, FGF23, CUL3, SEMA7A, CNTNAP1, KLF7, UNC5C, NUMB, PEA15, NRP2, ARHGEF7, RPS6KA4, RPS6KA5, KL, NRXN3, NRXN1, PSMF1, NRG2, FEZ2, RAPGEF2, SEMA3E, ARHGEF11, RBX1, RANBP9, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, AKAP9, RASA4, PSME3, PSMD14 |
776 | GO:0045926 | 0.00 | 3.20 | 8.74 | 17 | 30 | negative regulation of growth | ALOX15B, BMP4, CD36, CTSG, CXADR, FGFR3, GPC3, GNAS, IFNG, IL10, IL12B, KCNK2, PTCH1, PTEN, PTK2, SLC6A4, TP73 |
777 | GO:0045597 | 0.00 | 3.19 | 14.81 | 29 | 52 | positive regulation of cell differentiation | ACVR1B, ARNT, ARNTL, KLF5, CCNE1, CDX2, CLU, CMKLR1, CTGF, ETS1, FGFR3, GATA4, GATA6, GPC1, PRMT1, HSF4, HTR2C, INS, JUNB, KDR, PA2G4, PTGS2, RPS6KA1, RPS6KA3, SULT1E1, TAL1, ZNF16, EOMES, SOCS3 |
778 | GO:0032508 | 0.00 | 3.19 | 10.83 | 21 | 37 | DNA duplex unwinding | ANXA1, ATRX, CHD2, CHD4, DDX1, DDX3X, DDX11, ERCC3, HMGA1, PURA, RAD51, SUPV3L1, WRN, XRCC5, CDC45, RUVBL1, RECQL5, CHD1L, GINS1, RAD50, G3BP1 |
779 | GO:0070911 | 0.00 | 3.19 | 10.83 | 21 | 37 | global genome nucleotide-excision repair | DDB1, ERCC3, ERCC4, PCNA, RAD23B, RFC1, RFC3, RFC4, RFC5, RPA2, RPA3, RPS27A, SUMO3, UBB, SUMO1, XPA, CUL4A, COPS3, COPS2, CHD1L, RBX1 |
780 | GO:0071320 | 0.00 | 3.19 | 10.83 | 21 | 37 | cellular response to cAMP | APP, AQP1, ASS1, CPS1, CRHBP, RAPGEF1, ITPR3, KCNQ1, PENK, PTAFR, RAP1A, SLC8A1, SLC8A3, SRD5A1, STC1, AKAP1, AKAP7, AKAP6, RAPGEF2, HCN4, AKAP9 |
781 | GO:0042127 | 0.00 | 3.19 | 27.39 | 54 | 99 | regulation of cell proliferation | ABL2, AGTR1, AHR, ANGPT1, XIAP, FXYD2, BLK, BMX, BTK, CHEK1, CLC, CREB1, DBH, DHCR7, DNMT1, EMX1, FGR, NR5A2, FYN, CXCL2, CXCL3, GRPR, GUCY2C, HHEX, INHA, JUNB, JUND, JUP, LMO1, SERPINE1, PF4V1, PTGER2, PTGS1, RPA3, SALL1, SAT1, CXCL6, SGK1, SOS2, STAT6, TAL1, TNFRSF1A, TNFRSF1B, TYK2, XRCC5, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, TNFSF18, ARHGEF2, NUAK1, SGK2, PRG4 |
782 | GO:0071333 | 0.00 | 3.19 | 8.75 | 17 | 30 | cellular response to glucose stimulus | CYBA, SLC29A1, GATA4, GHRHR, ICAM1, IGF1, IGF1R, IL1R1, KCNJ11, MEN1, PAX2, SERPINF1, RAP1A, SMARCA4, SOX4, SRF, OGT |
783 | GO:0009636 | 0.00 | 3.19 | 38.92 | 75 | 133 | response to toxic substance | AHR, ALAD, ALB, ARG1, ASNS, ASS1, BAX, CASP8, CASP9, CAT, CCNB1, CD36, CDH1, CDK2, CDK4, CDKN1A, CHKA, CHUK, CNP, CPOX, CPS1, CYP2F1, DHFR, DNMT1, DNMT3A, DNMT3B, ERCC6, ETS1, GPX1, GPX2, GRIA4, GSTZ1, GUCY2C, HBA1, HBA2, HMBS, HP, HSPA9, ID1, KCNC2, MGMT, CIITA, PRDX1, PENK, PPP2CB, MAPK1, MAPK3, PTGS1, PTGS2, RAD51, RPS6KB1, S100A9, SCN2B, SCN8A, SDC1, SEPW1, SHC1, SLC6A4, SLC9A1, SOD2, SOD3, SRD5A1, SRF, PRDX2, TYMS, UQCRFS1, UROS, XPA, SLC30A1, OGT, RGN, SLC22A8, GSTO1, HDAC6, DHRS2 |
784 | GO:0035637 | 0.00 | 3.18 | 34.24 | 66 | 117 | multicellular organismal signaling | ATP1A1, ATP1A2, ATP1A3, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, CACNA1A, CACNB1, CACNB2, CACNB4, CACNG1, CALM3, CASQ1, CASQ2, CHRNB4, CXADR, DPP6, DRD5, S1PR1, GLRA1, HRC, IFNG, ITGA2, ITPR1, ITPR3, JUP, KCNA1, KCNA5, KCND2, KCND3, KCNH2, KCNJ2, KCNJ11, KCNJ14, KCNK3, KCNQ1, NRCAM, P2RX1, P2RX3, P2RX4, FXYD3, PLN, RYR1, RYR2, SCN1A, SCN2A, SCN2B, SCN4B, SCN5A, SCN7A, SCN8A, SLC8A1, SLC8A3, SLC9A1, TNNI3, TNR, TRPC1, CNTNAP1, KCNK6, NUP155, HCN4, ABCC9, AKAP9, KCNMB2 |
785 | GO:0043502 | 0.00 | 3.17 | 8.78 | 17 | 30 | regulation of muscle adaptation | CAMK2G, CASQ1, CAV3, GTF2I, IGF1, P2RX4, RPS6KB1, SCN5A, SLC9A1, TNNC1, TRPC3, COL14A1, AKAP1, PDE5A, CTDP1, KLF4, AKAP6 |
786 | GO:1902305 | 0.00 | 3.17 | 8.78 | 17 | 30 | regulation of sodium ion transmembrane transport | ACTN4, ARF1, ATP1A2, FXYD2, CAV3, DNM2, DRD3, FXYD3, PRKCE, PTPN3, SCN2B, SCN4B, SCN5A, SLC9A1, SNTA1, YWHAH, SLC9A3R1 |
787 | GO:0030901 | 0.01 | 3.17 | 6.71 | 13 | 23 | midbrain development | APLP2, PHOX2A, EN1, KAT2A, SMAD1, SMAD9, OTX1, OTX2, RFX4, RYK, WNT1, FZD3, FZD6 |
788 | GO:0034112 | 0.00 | 3.16 | 30.14 | 58 | 103 | positive regulation of homotypic cell-cell adhesion | ADA, ADAM8, ANXA1, BAD, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD28, CD86, CD44, CD59, CD74, CTLA4, CD55, DHPS, DPP4, EFNB1, EFNB2, EGR3, FLOT2, FYN, GATA3, GRB2, HAS2, IFNG, IGF1, IGF2, IHH, IL2RA, IL12B, IL18, ITGAL, PDPK1, PRKCQ, PTPN6, RAC1, RAG1, RARA, CCL21, XCL1, SPTA1, STAT5B, SYK, TRAF2, TNFSF4, VAV1, ZP3, AP3B1, TNFSF14, TNFSF9, RIPK2, IL1RL2, VNN1, AP3D1, GRAP2 |
789 | GO:0010035 | 0.00 | 3.15 | 38.88 | 75 | 135 | response to inorganic substance | ABAT, ALB, ANXA11, APBB1, APP, ASCL1, ASS1, ATP12A, BAX, BGLAP, BMP4, BSG, C3, CALM3, CASP8, CASP9, CASQ2, CD9, CD14, CD36, ENTPD6, CDK4, CLU, CPOX, CPS1, CYB5A, DHFR, DNMT3A, ERCC6, FGA, GDI1, GSS, HMGCS2, ICAM1, IL1A, IL1R1, ITPR3, KRT14, LCAT, LIPC, LTA4H, P2RX7, PRDX1, PAM, PCNA, PENK, PLN, PTCH1, PTEN, PTH, PTGS2, QDPR, RYR2, S100A8, S100A13, SIPA1, SOD2, SOD3, SORD, SPARC, TAT, PRDX2, TNNC1, TRPC1, TRPC3, SCGB1A1, SLC30A1, SLC30A2, FGF23, SLC14A2, SLC25A12, RGN, PDCD6, SLC25A13, KCNMB2 |
790 | GO:0006308 | 0.01 | 3.15 | 6.73 | 13 | 23 | DNA catabolic process | APAF1, BAX, DFFA, DFFB, DNASE1, DNASE1L1, DNASE1L2, DNASE1L3, ISG20, KPNA1, SETMAR, RGN, TATDN2 |
791 | GO:0007157 | 0.01 | 3.15 | 6.73 | 13 | 23 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | CD6, CXADR, GRID2, ICAM1, ITGA4, ITGA5, ITGAL, CD200, REG3A, PVR, SELE, SELP, NRXN1 |
792 | GO:0071869 | 0.01 | 3.15 | 6.73 | 13 | 23 | response to catecholamine | ABL1, APP, DNM2, DRD5, GNAS, ID1, KCNQ1, PDE4B, PENK, RYR2, SLC9A1, SNCA, SRD5A1 |
793 | GO:1901532 | 0.01 | 3.15 | 6.73 | 13 | 23 | regulation of hematopoietic progenitor cell differentiation | PRMT1, KDR, SOS2, ZNF16, HIST1H4I, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L |
794 | GO:0002690 | 0.00 | 3.15 | 11.40 | 22 | 39 | positive regulation of leukocyte chemotaxis | ADAM10, CD74, CCR1, EDNRA, F7, PTK2B, CXCL2, CXCL3, SERPINE1, PF4V1, RAC1, RAC2, S100A7, CCL21, CXCL6, CXCL5, XCL1, ADAM17, VEGFA, VEGFB, TNFSF14, CXCL14 |
795 | GO:0007588 | 0.00 | 3.15 | 11.40 | 22 | 39 | excretion | AGTR1, AGTR2, ANPEP, AQP5, AQP6, AVPR2, CLCNKA, CLCNKB, COMT, DRD3, EDNRB, GUCA2B, KCNJ1, KNG1, SCNN1B, SCNN1G, SCTR, SLC12A1, STC1, TACR2, SLC9A3R1, GRHPR |
796 | GO:0002758 | 0.00 | 3.15 | 19.16 | 37 | 66 | innate immune response-activating signal transduction | ADAM8, CALM3, EP300, FYN, ICAM2, ITPR1, ITPR3, PRKACB, PRKACG, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RAF1, SYK, UBA3, PSMF1, PSME3, PSMD14 |
797 | GO:0009749 | 0.00 | 3.15 | 9.31 | 18 | 32 | response to glucose | ACVR2B, ANGPT2, COL6A2, CTGF, EIF2B1, ENSA, PTK2B, GYS2, PRKCQ, PTEN, RPS6KB1, SLC2A2, SLC8A1, SREBF1, TRH, NR0B2, EIF2B3, EIF2B2 |
798 | GO:0046634 | 0.00 | 3.15 | 11.41 | 22 | 39 | regulation of alpha-beta T cell activation | ADA, ANXA1, CBLB, CD3E, CD28, CD86, CD55, GATA3, IFNG, IHH, IL12B, IL18, IRF1, PRKCQ, RARA, XCL1, SYK, TNFSF4, AP3B1, RIPK2, AP3D1, TNFSF18 |
799 | GO:0034332 | 0.00 | 3.14 | 23.41 | 45 | 80 | adherens junction organization | ACTB, ACTN1, ACVRL1, ANG, ARHGAP6, CDH1, CDH6, CDH7, CDH8, CDH9, CDH10, CDH12, CDH15, CTNNA1, CTNND1, DAPK3, EFNA5, CTTN, EPHA3, PTK2B, GPM6B, HRG, ITGA2, JUP, KDR, SMAD3, SMAD7, PDPK1, PTEN, PTK2, PTPRJ, PVR, RAC1, SDC4, SLC9A1, TBCD, TRIP6, TSC1, VCL, VEGFA, NUMB, ARHGEF7, ITGB1BP1, PPM1F, SLK |
800 | GO:0006874 | 0.00 | 3.14 | 55.02 | 105 | 188 | cellular calcium ion homeostasis | ABL1, ABL2, ADCYAP1R1, ADRA1B, AGTR1, ANXA6, APP, ATP1A2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, AVPR1B, BAX, BDKRB1, BMP4, CACNA1A, CACNB4, CALM3, CASQ1, CASQ2, CAV3, CD4, CD36, CD40, CD52, CCR1, CCR3, CCR8, CYBA, CD55, DIAPH1, DRD3, DRD5, S1PR1, LPAR1, EDNRA, EDNRB, EPOR, F2, F2R, PTK2B, GALR1, GNA15, GNAT2, GNG3, XCR1, GRINA, GRM1, GTF2I, HEXB, HRC, HTR2C, IL13, ITGB1, ITPR1, ITPR3, KCNA5, KCNK3, KISS1, KNG1, NTSR1, OXTR, P2RX3, P2RX4, P2RX5, P2RX7, P2RY2, P2RY4, PDPK1, PLN, PRKCB, PRKCE, PRKD1, PTH, PTPN6, PYGM, RYR1, RYR2, CCL21, XCL1, SLC8A1, SLC8A3, SNCA, STC1, TNNI3, TPT1, HSP90B1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, VDR, TRPV1, WFS1, SLC30A1, S1PR4, INPP4B, RGN, VAPB, GSTO1, AKAP6, ATG5, ATP2C2 |
801 | GO:2001056 | 0.00 | 3.14 | 18.73 | 36 | 64 | positive regulation of cysteine-type endopeptidase activity | APAF1, BAD, BAX, BOK, CASP8, CASP9, CD14, COL4A3, CTGF, CTSH, DDX3X, F2R, F3, HIP1, IFI16, SMAD3, P2RX1, REST, RET, RPS3, S100A8, S100A9, SNCA, TRAF2, TRADD, RIPK1, CRADD, TNFSF10, TNFRSF10B, TNFRSF10A, EIF2AK3, PPM1F, TNFSF15, CASP8AP2, PDCD6, BCL2L11 |
802 | GO:0070555 | 0.02 | 3.13 | 4.66 | 9 | 16 | response to interleukin-1 | AES, ANXA1, CYBA, ETS1, HNMT, PRKCI, SELE, SNCA, RIPK2 |
803 | GO:0002444 | 0.02 | 3.13 | 4.67 | 9 | 16 | myeloid leukocyte mediated immunity | ANXA3, BCR, C3, CTSG, ACE, PTAFR, STXBP3, ADAM17, STX11 |
804 | GO:0008306 | 0.02 | 3.13 | 4.67 | 9 | 16 | associative learning | CRH, DRD5, GABRA5, PPT1, SNAP25, SRF, TNR, RIN1, EIF4A3 |
805 | GO:0071417 | 0.00 | 3.12 | 95.68 | 181 | 330 | cellular response to organonitrogen compound | ADCY1, ADCY7, ANGPT1, ANXA5, APRT, ARAF, ARG1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, CALM3, CAMK2A, CAMK2G, CDC6, CDH1, CDK2, COL1A1, COL6A1, CREB1, CSF2, CSF2RB, CSH1, CTNNA1, CYBA, CYP11B1, DNMT1, DNMT3A, DNMT3B, DUSP5, DUSP7, DUSP9, EIF4B, EIF4E, EIF4EBP2, FBN1, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FYN, GCG, GCGR, GH2, GHRHR, GHSR, GLRA1, GNB2, GNG3, GNG10, GNRHR, GPLD1, FFAR3, GRB2, GRIN2A, NRG1, HMGCS2, NR4A1, IGF1, IGF1R, IGF2, IL2RA, IL2RB, IL2RG, IL3, INS, JUP, KIT, IPO5, MARK3, RAB8A, MEN1, KITLG, FOXO4, YBX1, NTRK2, P2RX4, P2RY11, PDK4, PDPK1, PIK3C2A, PPP5C, PRKAA1, PRKAB2, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCB, PRKCI, PRKCQ, MAPK1, MAPK3, PRL, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTGS2, PTK2, PTPN2, PTPN6, PTPRA, PTPRE, RAF1, RANGAP1, RASA2, RHEB, RPS6, RPS6KB1, RPS27A, RXRA, SRSF5, SHC1, SHMT1, SLC2A4, SLC6A4, SMARCC1, SOX9, SPTA1, SPTB, SREBF1, STAT3, STAT5B, ADAM17, KLF10, HSP90B1, TSC1, UBB, USF1, WNT1, FGF23, CUL3, OGT, PIK3R3, PEA15, RIPK2, ATP6V0E1, SOCS3, ATP6V0D1, IL1RL1, ARHGEF2, KLF4, GLP2R, SLIT2, KL, PSMF1, NRG2, ATP6V1G1, BCAR1, C2CD5, NR1H4, RBX1, RASA4, PSME3, PSMD14 |
806 | GO:0002053 | 0.02 | 3.11 | 4.68 | 9 | 16 | positive regulation of mesenchymal cell proliferation | ARHGAP5, BMPR1A, FGF9, IHH, KDR, SOX9, VEGFA, TP63, CHRD |
807 | GO:0006110 | 0.02 | 3.11 | 4.68 | 9 | 16 | regulation of glycolytic process | ARNT, IGF1, INS, P2RX7, PGAM1, PRKAA1, PRKAG1, STAT3, OGT |
808 | GO:0009649 | 0.02 | 3.11 | 4.68 | 9 | 16 | entrainment of circadian clock | CHRM1, CRY2, GNAQ, ID2, PPP1CA, RBM4, SOX14, USP2, CLOCK |
809 | GO:0030449 | 0.02 | 3.11 | 4.68 | 9 | 16 | regulation of complement activation | C3, C7, CD59, CR1, CD55, CFP, PHB, PROS1, VTN |
810 | GO:0042104 | 0.02 | 3.11 | 4.68 | 9 | 16 | positive regulation of activated T cell proliferation | CD86, IGF1, IGF2, IL2RA, IL12B, IL18, STAT5B, TNFSF4, TNFSF9 |
811 | GO:0048488 | 0.02 | 3.11 | 4.68 | 9 | 16 | synaptic vesicle endocytosis | AMPH, CANX, CDK5, OPHN1, ITSN1, SNCA, SYT1, SYT5, SYNJ1 |
812 | GO:0060008 | 0.02 | 3.11 | 4.68 | 9 | 16 | Sertoli cell differentiation | NR0B1, ATRX, GATA4, HSD17B4, ICAM1, RARA, SDC1, SOX9, AKAP9 |
813 | GO:1901381 | 0.02 | 3.11 | 4.68 | 9 | 16 | positive regulation of potassium ion transmembrane transport | DNM2, DPP6, KCNC2, KCNH2, KCNJ2, KCNQ1, AKAP7, AKAP6, AKAP9 |
814 | GO:0001704 | 0.00 | 3.11 | 7.28 | 14 | 25 | formation of primary germ layer | COL6A1, COL11A1, DUSP1, DUSP5, GATA4, GATA6, HSBP1, ITGA4, ITGA5, ITGA7, ITGAV, ITGB5, LAMA3, VTN |
815 | GO:0031397 | 0.00 | 3.11 | 29.85 | 57 | 102 | negative regulation of protein ubiquitination | ABL1, BUB1, BUB1B, TSPO, CCNB1, CDC20, CDC27, CDK5, CENPF, DUSP1, FYN, LIMK1, MAD2L1, SMAD7, PRKCE, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS3, RPS27A, SOX4, TTK, UBB, UBE2D1, USP4, WNT1, ZNF207, OGT, CDC23, CDC16, ZW10, BUB3, TRIP12, ATG5, PSMF1, BAG5, PSME3, PSMD14 |
816 | GO:0030168 | 0.00 | 3.11 | 43.61 | 83 | 149 | platelet activation | ABAT, ACTB, ACTN4, ACTN1, ALB, APP, AXL, DAGLA, CALM3, CD9, CD36, ENTPD2, CD40, CD63, CLU, COL1A1, CSRP1, DGKB, F2, F2R, F2RL2, FGA, FYN, GNA15, GNAI1, GNAI3, GNAQ, GNAS, GP1BA, GP9, GRB2, HGF, HRG, HSPB1, IGF1, IGF2, ILK, ITPR1, ITPR3, KNG1, LAMP2, P2RX1, SERPINE1, PDPK1, PF4V1, PRKCB, PRKCE, PRKCQ, PRKG1, MAPK1, MAPK3, PROS1, PSAP, PTK2, PTPN6, RAC1, RAC2, RAF1, RAP1A, RAP2B, CX3CL1, SELP, SHC1, SPARC, SRF, STXBP3, SYK, TRPC3, TUBA4A, TYRO3, VAV1, VCL, VEGFA, VEGFB, YWHAZ, FZD6, DGKE, DGKI, BCAR1, GNA14, WDR1, RASGRP2, ABCC4 |
817 | GO:0051438 | 0.00 | 3.10 | 19.86 | 38 | 68 | regulation of ubiquitin-protein transferase activity | ABL1, BMI1, CDK2, LIMK1, SMAD7, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS27A, SKP1, UBB, UBE2L3, CUL1, CDC14B, PSMF1, BAG5, FEM1B, PSME3, PSMD14 |
818 | GO:0070661 | 0.00 | 3.10 | 15.12 | 29 | 52 | leukocyte proliferation | ABL1, AHR, BAX, CD151, CLC, CLU, CR2, ACE, FLT3, FYN, HPRT1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IMPDH1, IMPDH2, IRF1, ITGAD, LMO1, P2RX7, RAC2, RAG2, SATB1, SOS2, TNFSF14, TNFSF18 |
819 | GO:0051349 | 0.00 | 3.09 | 7.31 | 14 | 25 | positive regulation of lyase activity | ADCYAP1R1, AVPR2, CALM3, DRD5, EDNRA, FSHR, GHRHR, GNAS, NTRK2, P2RY11, RAF1, VIP, VIPR2, WFS1 |
820 | GO:0050881 | 0.00 | 3.09 | 7.31 | 14 | 25 | musculoskeletal movement | ATP2A1, CASQ1, CAV3, CHUK, GAA, ITPR1, KCNJ2, RPS6KB1, SLC8A3, TNNC2, TNNC1, TNNI2, TNNI3, GSTO1 |
821 | GO:0002562 | 0.00 | 3.09 | 7.32 | 14 | 25 | somatic diversification of immune receptors via germline recombination within a single locus | CD28, CD40, IFNG, IL10, RAG1, RAG2, STAT6, TNFSF4, UNG, TNFSF13, RNF8, EXO1, IL27RA, VPRBP |
822 | GO:0050766 | 0.00 | 3.09 | 7.32 | 14 | 25 | positive regulation of phagocytosis | BCR, C3, CD36, CYBA, DNM2, ITGA2, ITGAV, MFGE8, PROS1, RAB27A, RAP1A, RAP1GAP, SFTPD, TULP1 |
823 | GO:0043044 | 0.00 | 3.07 | 12.58 | 24 | 43 | ATP-dependent chromatin remodeling | ACTB, ACTL6A, CENPA, CHD4, CENPI, HNRNPC, RBBP4, SMARCA1, SMARCA4, SMARCC1, SMARCE1, ARID1A, HIST1H4I, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, RUVBL1, RNF8 |
824 | GO:2000021 | 0.00 | 3.07 | 23.62 | 45 | 81 | regulation of ion homeostasis | ABL1, ADCYAP1R1, ATP1A2, BAX, BDKRB1, BMP4, CALM3, CASQ1, CASQ2, CD4, CYBA, DIAPH1, EDNRA, F2, F2R, PTK2B, XCR1, HRC, HTR2C, IL13, ITPR1, ITPR3, P2RX3, P2RX4, P2RX5, PDPK1, PLN, PRKCE, PRKD1, PTPN6, RYR1, RYR2, CCL21, XCL1, SLC8A1, SNCA, TRPC1, TRPC3, TRPV1, SLC30A1, SLC30A2, AP3D1, GSTO1, AKAP6, ATG5 |
825 | GO:0006367 | 0.00 | 3.07 | 34.76 | 66 | 119 | transcription initiation from RNA polymerase II promoter | NR0B1, RUNX2, CCNC, CCNT2, CDK8, COX6A1, COX6B1, COX7B, COX7C, COX8A, CTGF, E2F5, ERCC3, ESRRG, NR5A2, GPI, GPX2, GTF2I, NR4A1, HNF4G, RBPJ, JUNB, SMAD3, SMAD7, MAZ, MEN1, PRDX1, SERPINE1, PGR, PRKAA1, PRKAB2, PRKAG1, RARA, RARB, RHEB, RPS27A, RXRA, RXRG, SP1, TAF4B, TAF7, TAF10, TBP, PRDX2, NR2F1, NR2E1, NR2C1, NR2C2, TSC1, UBB, UBE2D1, NR1H2, VDR, YWHAH, YWHAZ, ZNF45, USP9X, NR0B2, TP63, COX5A, NR1D1, NR1I3, NR1H4, NR1D2, NR2E3, TRIM28 |
826 | GO:0061458 | 0.00 | 3.06 | 66.43 | 125 | 227 | reproductive system development | ADA, NR0B1, AHR, ALOX15B, ANG, ANXA1, ARNT, ASCL2, ATRX, AXL, BAX, BCL2L1, BIK, PRDM1, BMP4, BMPR2, BOK, BRCA2, BSG, CAPN5, CASP8, CCNE1, CCNF, CD44, CDX2, CHAT, COL9A3, CSF2, CTNNA1, CYP27B1, DCN, EPOR, ETV2, FANCF, FANCG, FGF7, FGF8, FGF9, FSHB, CENPI, FSHR, GATA3, GATA4, GATA6, GDF9, GHSR, GJB2, GRB2, HSD17B3, HSD17B4, ICAM1, IDH1, IGF1, IGF1R, RBPJ, IL10, ING2, INHA, ITGA4, JUNB, KDR, KIT, LLGL2, MEN1, KITLG, SERPINE1, SERPINF1, PGR, SERPINB5, PRKACG, MAPK1, PSAP, PTEN, PTGIS, PTGS2, PTK2, PTPRN, RARA, RRM1, RXRA, SALL1, SDC1, SLC8A1, SMARCC1, SNAI1, SOX9, SP1, SP3, SRD5A1, SRY, ST14, STAT5B, STC1, NR2F2, TSPY1, TYRO3, UBB, UBE3A, VDR, VEGFA, ZP3, FZD5, FOSL1, NRIP1, ARID1A, EOMES, FZD4, UTF1, TP63, AKR1C3, ADAM15, SGPL1, EIF2B2, EIF2S2, SOCS3, BMP15, SLIT2, HAND1, CUL7, REC8, BCL2L11, FEM1B, AKAP9, TRIM28, IRX5 |
827 | GO:0071897 | 0.00 | 3.05 | 10.50 | 20 | 36 | DNA biosynthetic process | CENPF, CTGF, DDB1, DNTT, PCNA, PHB, REV3L, RFC1, RFC4, RFC5, RPA2, RPA3, RPS27A, TYMS, UBB, UBA7, UFD1L, TRIM25, CUL4A, RBX1 |
828 | GO:0002474 | 0.00 | 3.05 | 18.44 | 35 | 63 | antigen processing and presentation of peptide antigen via MHC class I | CANX, CD36, CTSS, CYBA, ACE, ITGAV, ITGB5, ABCB1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS27A, UBB, PSMF1, PSME3, PSMD14 |
829 | GO:0006919 | 0.00 | 3.05 | 10.51 | 20 | 36 | activation of cysteine-type endopeptidase activity involved in apoptotic process | APAF1, BAD, BOK, CASP9, COL4A3, CTSH, F2R, F3, HIP1, P2RX1, RET, S100A8, S100A9, SNCA, CRADD, EIF2AK3, TNFSF15, CASP8AP2, PDCD6, BCL2L11 |
830 | GO:0045321 | 0.00 | 3.04 | 24.61 | 47 | 86 | leukocyte activation | ABL2, BAX, BMX, ZFP36L2, BST2, CASP8, RUNX2, CD7, CD8A, TNFSF8, CD151, CDK6, CEBPG, CR2, CXADR, EP300, EPHB1, HHEX, ONECUT1, HPRT1, IL2RB, IMPDH1, IMPDH2, INS, ITGA4, ITGAD, ITGB1, SMAD3, P2RX7, PRKCB, RAG2, RPL22, SATB1, SELPLG, SOX4, SP3, SRF, ADAM17, TPD52, WAS, WNT1, ZNF3, FZD5, FZD7, FZD8, FZD9, VPRBP |
831 | GO:0070613 | 0.02 | 3.04 | 5.25 | 10 | 18 | regulation of protein processing | BIRC3, XIAP, BIRC5, GAS1, SERPINE1, PRKACB, RFX4, RPS6KA2, IFT88, TMEM59 |
832 | GO:0051321 | 0.02 | 3.04 | 5.25 | 10 | 18 | meiotic cell cycle | DUSP1, NUMA1, OVOL1, PRKACB, RBBP8, NR2C2, TUBG1, EXO1, BUB3, UTP14C |
833 | GO:0006305 | 0.00 | 3.04 | 13.17 | 25 | 45 | DNA alkylation | ATRX, DNMT1, TRDMT1, DNMT3A, DNMT3B, GNAS, H3F3B, MGMT, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, FKBP6, HIST1H3F, PICK1, TRIM28 |
834 | GO:0006936 | 0.00 | 3.04 | 23.13 | 44 | 80 | muscle contraction | ACTA2, ACTG2, ANXA1, ARG2, ATP1A3, CACNG1, CHRNB2, CHUK, CRYAB, DTNA, EDNRA, EDNRB, EMD, GAA, GDNF, GLRA1, HSBP1, ITGA1, ITGB5, KCNA5, KCNH2, KNG1, P2RX3, PIK3C2A, RPS6KB1, RYR1, SCN2B, SCN4B, SCN7A, SRSF1, SGCA, SMTN, SLC6A8, SNTA1, SNTB1, TAZ, VCL, VEGFB, TRPV1, DYSF, STBD1, NUP155, ARHGEF11, COL4A3BP |
835 | GO:0030219 | 0.02 | 3.04 | 5.26 | 10 | 18 | megakaryocyte differentiation | EP300, KIT, PIP4K2A, PTPN6, SP1, SP3, SRF, TAL1, ZNF16, WASF2 |
836 | GO:0032768 | 0.00 | 3.03 | 7.90 | 15 | 27 | regulation of monooxygenase activity | AGTR2, CALM3, CAV3, SCARB1, CNR1, CYP27B1, DHFR, DNM2, PTK2B, FCER2, GDNF, IFNG, INS, SNCA, VDR |
837 | GO:0043535 | 0.00 | 3.03 | 7.90 | 15 | 27 | regulation of blood vessel endothelial cell migration | ACVRL1, AGTR2, ANGPT1, ANGPT2, EFNA1, EPHA2, HRG, HSPB1, PRCP, PRKD1, PTGS2, NR2E1, VEGFA, ITGB1BP1, KLF4 |
838 | GO:0001662 | 0.02 | 3.03 | 5.27 | 10 | 18 | behavioral fear response | CRH, DBI, DPP4, EIF4E, GABRA5, HTR2C, PENK, RPS6KB1, NR2E1, VDAC1 |
839 | GO:0019433 | 0.02 | 3.03 | 5.27 | 10 | 18 | triglyceride catabolic process | APOH, CPS1, FABP2, FABP7, GPLD1, LIPC, LIPE, PPP1CA, PRKACB, PRKACG |
840 | GO:0030513 | 0.02 | 3.03 | 5.27 | 10 | 18 | positive regulation of BMP signaling pathway | ACVRL1, BMP4, BMPR2, FOXD1, GATA4, GATA6, GPC3, RBPJ, ILK, SOX11 |
841 | GO:0045744 | 0.02 | 3.03 | 5.27 | 10 | 18 | negative regulation of G-protein coupled receptor protein signaling pathway | ADA, ADRBK1, BICD1, DNM1, DNM2, DRD3, PALM, RGS12, RGS13, SNCA |
842 | GO:0051646 | 0.02 | 3.03 | 5.27 | 10 | 18 | mitochondrion localization | ALB, ATP2A1, KAT2A, MAP1B, OPA1, UBB, UXT, OGT, MFN2, HDAC6 |
843 | GO:0051932 | 0.02 | 3.03 | 5.27 | 10 | 18 | synaptic transmission, GABAergic | CLCN3, CNR1, DNM1, GABRB2, OXTR, PRKCE, PTEN, RAC1, RAC3, SYN3 |
844 | GO:1902622 | 0.02 | 3.03 | 5.27 | 10 | 18 | regulation of neutrophil migration | ADAM8, CD74, EDNRA, CXCL2, CXCL3, RAC1, RAC2, CCL21, XCL1, SLIT2 |
845 | GO:0060326 | 0.00 | 3.03 | 8.41 | 16 | 29 | cell chemotaxis | AGTR1, LPAR1, EGR3, EPHA2, EPHB1, FGF4, HGF, NR4A1, HRG, HSPB1, KDR, PRKD1, PRKCQ, SAA4, NRP1, BCAR1 |
846 | GO:0048015 | 0.00 | 3.02 | 33.95 | 64 | 116 | phosphatidylinositol-mediated signaling | ANGPT1, BAD, CASP9, CAT, CBL, CD28, CD86, CDKN1A, CHUK, CREB1, CRYBA1, CSF1R, DCN, F2, F2R, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FGR, FLT1, FLT3, FSHR, FYN, GATA3, GRB2, HCLS1, HGF, NRG1, NR4A1, IGF1, IGF1R, INS, KDR, KIT, KITLG, FOXO4, NTRK2, PDPK1, PIK3C2A, PIK3C2B, PI4KA, PTAFR, PTEN, PTK2, PTPN6, RPS6KB1, RPS6KB2, SELP, SOX9, TYRO3, UBE3A, VAV1, ZP3, FGF23, OGT, KLF4, KL, SLC9A3R1, NRG2, GAB2 |
847 | GO:0009416 | 0.00 | 3.02 | 32.81 | 62 | 113 | response to light stimulus | ABCA4, ABL2, ADRA1B, APP, ASNS, ATP1A2, ATP1A3, OPN1SW, CACNB4, CDK5, AKR1C4, CHRM1, CHRNB2, CLU, CLPS, CREB1, CTNS, DBH, DNM2, DRD3, DUSP1, ELK1, GPC4, GPC5, OPN1MW, GPC3, GNAQ, GNAT2, GNGT2, GPC1, GRIN2A, HMGCR, HRH1, ID2, ITGB1, JUNB, JUND, KCNC2, KIT, NTRK2, PPP1CA, PTPRZ1, RBM4, RBP1, RBP2, OPN1LW, RGR, RLBP1, SDC1, SDC4, SGK1, ELOVL4, TRPC3, TULP1, LRP8, COPS3, AKR1C3, UNC119, USP2, CLOCK, SDC3, NR2E3 |
848 | GO:0008361 | 0.00 | 3.02 | 11.08 | 21 | 38 | regulation of cell size | ADD1, AQP1, ARHGAP5, ATP2B2, CAV3, CDK4, CLCN3, CLCN6, CLNS1A, CREB1, KCNN4, P2RX7, PTEN, RAC1, RET, TP73, TSC1, VAV1, OGT, SLC9A3R1, RB1CC1 |
849 | GO:1900046 | 0.00 | 3.01 | 13.75 | 26 | 47 | regulation of hemostasis | ABAT, ANXA5, APOH, CD36, F2, F2R, F3, F7, F12, FAP, FGA, GP1BA, FOXA2, HRG, KLKB1, KNG1, SERPINE1, PRKCQ, PRKG1, PROC, PROS1, S100A9, SELP, SYK, USF1, VTN |
850 | GO:0042770 | 0.00 | 3.01 | 25.46 | 48 | 87 | signal transduction in response to DNA damage | ABL1, ATR, ATRX, BCL3, BRCA2, CASP9, CD44, CD74, CDK2, CDKN1A, DDX5, GRB2, HIC1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS27A, SNAI1, SOX4, SP100, TP73, UBB, WNT1, SMC1A, TP63, CRADD, PSMF1, PSME3, PSMD14 |
851 | GO:0070098 | 0.00 | 3.00 | 11.12 | 21 | 38 | chemokine-mediated signaling pathway | CCR1, CCR3, CCR8, CMKLR1, CX3CR1, PTK2B, ACKR1, XCR1, GPR17, CXCL2, CXCL3, PF4V1, CCL21, CCL22, CCL25, CXCL6, CXCL5, XCL1, CX3CL1, XCL2, SLIT2 |
852 | GO:0072376 | 0.00 | 3.00 | 8.47 | 16 | 29 | protein activation cascade | C3, C7, CD59, CLU, CR1, CR2, CD55, FBLN1, FCN2, FGA, CFHR1, CFP, PHB, PROS1, VTN, FCN3 |
853 | GO:0006935 | 0.00 | 3.00 | 100.03 | 186 | 347 | chemotaxis | ABL1, ABL2, ACTB, AP2B1, APBB2, APP, ARAF, CACNB1, CACNB2, CACNB4, CALM3, CAMK2A, CAMK2G, CD72, CDK5, CHN1, AP2M1, AP2S1, CCR3, CCR8, COL2A1, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2, CSF2RB, CSNK2A1, CSNK2A2, DCC, DLG3, DLX5, DNM1, DPYSL3, DUSP5, DUSP7, DUSP9, TYMP, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EFNB2, EGR2, EPHA3, EPHA4, EPHA5, EPHA8, EPHB2, EPHB3, ETV1, ETV4, FGF3, FGF6, FGF9, FGFR3, FPR1, FPR2, FPR3, FYN, GATA3, GDNF, GFRA1, GPC1, XCR1, GRB2, GRIN2A, NRG1, IL2RA, IL2RB, IL2RG, IL3, ISL1, ITGA5, ITGAV, ITGB1, KIF5A, LIMK1, LSP1, MARK3, KITLG, NRCAM, NTN3, OPHN1, OTX2, PPP5C, MAPK1, MAPK3, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTAFR, PTK2, PTPN2, PTPRA, RAF1, RALA, RASA2, RNASE2, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RRAS, RYK, SCN5A, SEMA3F, ITSN1, SHC1, SIAH2, SOS2, SPTA1, SPTB, CNTN2, TNR, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, SEMA3B, FZD3, FOSL1, FGF23, CUL3, SEMA7A, CNTNAP1, KLF7, UNC5C, NUMB, PEA15, NRP2, ARHGEF7, RPS6KA4, USP14, RPS6KA5, KL, NRXN3, NRXN1, PSMF1, NRG2, FEZ2, RAPGEF2, SEMA3E, ARHGEF11, RBX1, RANBP9, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, AKAP9, RASA4, PSME3, PSMD14 |
854 | GO:0030198 | 0.00 | 2.99 | 35.05 | 66 | 121 | extracellular matrix organization | ACTN1, APBB2, APLP2, APP, BCL3, BMP4, DST, CD36, CD151, COMP, VCAN, CTGF, ELF3, FBLN1, FBLN2, EFEMP1, FGA, GFAP, B4GALT1, GPM6B, HAS1, HAS2, HAS3, ICAM1, ICAM2, ICAM4, IHH, ILK, ITGA6, ITGA1, ITGA2, ITGA4, ITGA5, ITGA7, ITGA9, ITGAD, ITGAE, ITGAL, ITGAM, ITGAV, ITGB1, ITGB5, KDR, LAMA4, LTBP2, MATN3, MFAP3, SERPINE1, SERPINB5, PPIB, PTK2, PTPRS, SDC1, SDC4, SNCA, SPARC, NR2E1, TNR, VTN, MADCAM1, LTBP4, RIPK1, NRXN1, SDC3, ADAMTSL2, SPOCK2 |
855 | GO:0043666 | 0.00 | 2.99 | 8.49 | 16 | 29 | regulation of phosphoprotein phosphatase activity | AGTR2, CALM3, CRY2, ENSA, ITGA1, PPP1R12A, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, SET, HSP90B1, TSC1, RGN, AKAP6, NUAK1 |
856 | GO:0001667 | 0.00 | 2.98 | 57.95 | 108 | 198 | ameboidal-type cell migration | ACVR1B, ACVRL1, AGTR2, ANGPT1, ANGPT2, ANXA3, APOH, AQP1, ARHGAP4, ARHGDIB, BMP4, BMPR2, KRIT1, SCARB1, CD63, CTSH, DCN, DPP4, EDNRB, EFNA1, EFNB1, EFNB2, EGR3, EPHA2, EMP2, ETS1, PTK2B, FAP, FGF4, FGF7, FGF8, FLT4, GATA3, GDNF, GPLD1, GPX1, HAS1, HAS2, NR4A1, HRG, HSPB1, ID1, IFNG, ILK, ISL1, ITGA2, ITGA4, ITGB1, JUN, KDR, KIT, KRT2, KRT16, KITLG, DDR2, PAX3, PDPK1, SERPINF1, PFN2, PRCP, PRKCE, PRKD1, PRKX, PROX1, PTEN, PTGS2, PTK2, PTPRR, RAC1, RET, S100A2, S100P, SDC4, SEMA3F, SLC8A1, SOX9, SOX10, SP100, SPARC, SRF, STC1, T, NR2F2, NR2E1, TNS1, VEGFA, VIL1, WNT11, SCG2, SEMA3B, SEMA7A, TNFSF12, NRP2, NRP1, ARHGEF7, SGPL1, PHOX2B, ITGB1BP1, KLF4, SLIT2, BAG4, BCAR1, PPM1F, SEMA3E, ZEB2, HDAC6, PDCD6, WASF2 |
857 | GO:0030282 | 0.01 | 2.98 | 5.83 | 11 | 20 | bone mineralization | FGFR3, GPC3, IGF1, PTGS2, PTN, KLF10, CLEC3B, TUFT1, WNT11, EIF2AK3, MINPP1 |
858 | GO:0050796 | 0.00 | 2.98 | 18.08 | 34 | 62 | regulation of insulin secretion | SLC25A4, ARL2, ARNTL, CACNA1A, CHRM3, CNR1, ENSA, GHSR, GNAS, IFNG, INS, ITPR1, ITPR3, KCNA5, KCNC2, KCNJ11, KCNS3, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, RAP1A, REST, RFX3, SLC2A2, SNAP25, SREBF1, SYT5, IQGAP1, SYT7, CLOCK, SPCS2 |
859 | GO:0009605 | 0.00 | 2.97 | 128.64 | 240 | 473 | response to external stimulus | ABL2, ACACB, ACADS, ACAT1, ACTB, AES, AHCY, ALB, ALDH1A3, ANGPT1, APAF1, APBB2, ARAF, ASCL1, ASGR1, ATF3, ATF4, ATP2B1, BCHE, BRCA2, CACNA1A, CACNB1, CACNB2, CAMK2A, CAMK2G, CAT, CCNE1, CD3E, CD63, CD72, CDK5, CDKN1A, CDKN2D, CHAT, CHN1, CCR3, CCR8, COL2A1, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2RB, CSNK2A1, DAD1, DCC, DHODH, DLG3, DLX5, DNM1, DNMT3A, DNMT3B, DPYSL3, DUSP5, DUSP7, DUSP9, TYMP, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EGR2, EGR3, EPHA2, ENSA, EPHA3, EPHA5, EPHA8, EPHB2, EPHB3, ETV4, FGF3, FGF6, FGF8, FGF9, FGFR3, FLT1, FPR1, FPR2, FPR3, G6PC, GCGR, GDNF, GFRA1, XCR1, GRB2, GSS, HGF, HLCS, HMBS, NR4A1, HRH1, HTR2C, IL2RB, IL2RG, IL3, INHA, ITGA6, ITGA1, ITGA5, ITGA9, ITGAV, KIF5A, LIMK1, LIPC, LSP1, MARK3, KITLG, MGMT, NUDT1, NRCAM, NTN3, OPHN1, OTX2, OXCT1, PAX2, PCK1, CHMP1A, PIM1, PPP5C, PRKAA1, PSPN, PROX1, PSMA1, PSMA3, PSMA4, PSMA5, PSMB1, PSMB2, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTH, PTK2, PTN, PTPRA, PTPRJ, RALA, RASA2, RHAG, RHCE, RHD, RNASE2, RPL24, RPS6KA1, RPS6KA2, RPS27A, RRAS, RXRA, RYK, SAA4, SATB1, SCN5A, CCL25, ITSN1, SHC1, SIAH2, SIPA1, SKP2, SLC6A4, SLC34A1, SLC22A3, SORD, SOS2, SPTA1, SPTB, SRD5A1, SRF, STC1, SUOX, CNTN2, KLF10, TRIO, TRPC1, TRPC4, TRPC5, TYMS, TYR, TYROBP, UBB, UPP1, VAV1, VDR, WNT11, WRN, FZD3, ARHGEF5, FGF23, CUL3, CNTNAP1, HAT1, KLF7, UNC5C, NUMB, PEA15, NRP2, ARHGEF7, KYNU, AP3D1, RPS6KA4, RPS6KA5, KL, NRXN3, LIPG, EIF2AK3, PICK1, PSMF1, NRG2, BCAR1, RAPGEF2, ATG13, ARHGEF11, RBX1, RANBP9, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, AKAP9, RASA4, PSME3, PSMD14 |
860 | GO:2001235 | 0.00 | 2.97 | 18.10 | 34 | 62 | positive regulation of apoptotic signaling pathway | AGTR2, APAF1, ATF3, BIK, CASP8, CD14, CTNNA1, CTSH, DAPK3, SMAD3, MAL, PPP1CA, PPP2R1A, PPP2R1B, PTEN, RET, SIGLEC1, TPD52L1, TRAF2, TRPS1, YWHAH, YWHAZ, TP63, DYNLL1, PEA15, TRADD, RIPK1, CRADD, HRK, TNFSF12, TNFSF10, TNFRSF10B, TNFRSF10A, PDCD7 |
861 | GO:0060402 | 0.00 | 2.97 | 12.22 | 23 | 42 | calcium ion transport into cytosol | ATP1A2, CASQ1, CASQ2, CYBA, DIAPH1, PTK2B, XCR1, HRC, HTR2C, ITPR1, ITPR3, PLN, PRKCE, PRKD1, PTPN6, RYR1, RYR2, CCL21, SLC8A1, SLC8A3, TRPM2, TRPV1, ATG5 |
862 | GO:0010632 | 0.00 | 2.96 | 31.02 | 58 | 106 | regulation of epithelial cell migration | ACVRL1, AGTR2, ANGPT1, ANGPT2, ANXA3, APOH, AQP1, BMP4, BMPR2, KRIT1, SCARB1, CD63, CTSH, DCN, EFNA1, EPHA2, EMP2, ETS1, PTK2B, FGF4, FGF7, FLT4, GATA3, GPLD1, HAS2, HRG, HSPB1, IFNG, ITGA2, JUN, KDR, PDPK1, SERPINF1, PFN2, PRCP, PRKCE, PRKD1, PROX1, PTGS2, PTK2, PTPRR, SOX9, SP100, SPARC, STC1, NR2F2, NR2E1, VEGFA, VIL1, NRP2, NRP1, ITGB1BP1, KLF4, SLIT2, BCAR1, PPM1F, HDAC6, PDCD6 |
863 | GO:0001975 | 0.01 | 2.96 | 5.85 | 11 | 20 | response to amphetamine | ADRA1B, CALM3, DBH, TRDMT1, DRD3, DRD5, GRIN2A, HPRT1, ICAM1, OXTR, RANBP2 |
864 | GO:0002204 | 0.01 | 2.96 | 5.85 | 11 | 20 | somatic recombination of immunoglobulin genes involved in immune response | CD28, CD40, IFNG, IL10, STAT6, TNFSF4, UNG, TNFSF13, RNF8, EXO1, IL27RA |
865 | GO:0043277 | 0.01 | 2.96 | 5.85 | 11 | 20 | apoptotic cell clearance | AXL, C3, CD36, SCARB1, FCN2, ITGAV, MFGE8, RAC1, RARA, TYRO3, FCN3 |
866 | GO:0050690 | 0.01 | 2.96 | 5.85 | 11 | 20 | regulation of defense response to virus by virus | AP2B1, ARF1, CD4, CD28, AP2M1, AP1S1, AP2S1, FYN, RAC1, AP1M1, AP1M2 |
867 | GO:0051954 | 0.01 | 2.96 | 5.85 | 11 | 20 | positive regulation of amine transport | ABAT, ADRBK1, CHRNB2, GDNF, NTSR1, OXTR, P2RX7, PCP4, RAB3B, TACR2, TRH |
868 | GO:0034329 | 0.00 | 2.96 | 15.95 | 30 | 55 | cell junction assembly | ACTB, ACTN1, ANG, DST, CD151, CDH1, CDH6, CDH7, CDH8, CDH9, CDH10, CDH12, CDH15, CTNND1, CTTN, PTK2B, ILK, ITGA6, ITGA2, ITGA5, KRT5, KRT14, LAMA3, SMAD7, PDPK1, PVR, RSU1, TNS1, TRIP6, ARHGEF7 |
869 | GO:0097306 | 0.00 | 2.96 | 12.25 | 23 | 42 | cellular response to alcohol | ABCA1, ADCY7, KLF9, CDH1, CRHBP, CTNNA1, DNMT3A, ELK1, GLRA1, GPLD1, IGF1, IL10, ITGA2, JUP, PRKAA1, PRKCE, PTAFR, PTCH1, RAD51, LRP8, NRIP1, KLF4, RAMP3 |
870 | GO:0034724 | 0.00 | 2.95 | 9.07 | 17 | 31 | DNA replication-independent nucleosome organization | ATRX, CENPA, CENPI, H3F3B, RBBP4, HIST1H4I, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, HAT1, RUVBL1 |
871 | GO:0045860 | 0.00 | 2.94 | 56.43 | 105 | 195 | positive regulation of protein kinase activity | ABL1, ACVR2B, ADCY1, ADCY7, ANG, ANGPT1, ARAF, BAX, BMP4, CAMK2A, CAMK2G, CD4, CDK5, CDKN1A, CENPE, CLU, CRKL, CSF2, CSF2RB, ACE, EFNA5, EMP2, F2R, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FYN, GCG, GRB2, RAPGEF1, GRIN2A, NRG1, IL2RA, IL2RB, IL2RG, IL3, IL12B, INS, MARK3, DDR2, PDPK1, PPP5C, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTK2, PTPRA, RAF1, RAP1A, RASA2, CCL21, SDC4, SPTA1, SPTB, STK10, WNT11, ZP3, LRP8, FGF23, CUL3, UNC119, VAPB, ITGB1BP1, KL, PSMF1, NRG2, SLK, RASSF2, ATG13, OXSR1, RBX1, AKAP9, RASA4, PSME3, PSMD14 |
872 | GO:0008015 | 0.01 | 2.94 | 7.40 | 14 | 26 | blood circulation | ANGPT1, BCR, COL4A3, CYB5R3, RCAN1, ELN, EPB41, MEOX2, OLR1, PTPRJ, XCL2, TACR2, VEGFA, SLIT2 |
873 | GO:0001889 | 0.00 | 2.94 | 16.03 | 30 | 55 | liver development | ACAT1, ADA, AK2, ARG1, ASNS, ASS1, CCNE1, CEBPG, DBP, GATA6, HGF, HMGCS2, ONECUT1, IGF2R, JARID2, JUN, LIPC, SMAD3, PHF2, QDPR, RARA, RXRA, SOX9, SP1, SP3, SRD5A1, STAT5B, IFT88, ONECUT2, RB1CC1 |
874 | GO:0008286 | 0.00 | 2.93 | 60.58 | 112 | 207 | insulin receptor signaling pathway | ANGPT1, ARAF, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, CALM3, CAMK2A, CAMK2G, CSF2, CSF2RB, DUSP5, DUSP7, DUSP9, EIF4B, EIF4E, EIF4EBP2, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FYN, GPLD1, GRB2, GRIN2A, NRG1, IGF1R, IGF2, IL2RA, IL2RB, IL2RG, IL3, INS, KIT, MARK3, KITLG, FOXO4, YBX1, PDK4, PDPK1, PIK3C2A, PPP5C, PRKAA1, PRKAB2, PRKAG1, PRKCB, PRKCQ, MAPK1, MAPK3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTK2, PTPN2, PTPRA, PTPRE, RAF1, RASA2, RHEB, RPS6, RPS6KB1, RPS27A, SHC1, SMARCC1, SPTA1, SPTB, SREBF1, TSC1, UBB, FGF23, CUL3, OGT, PIK3R3, PEA15, ATP6V0E1, SOCS3, ATP6V0D1, KL, PSMF1, NRG2, ATP6V1G1, BCAR1, RAPGEF2, C2CD5, RBX1, AKAP9, RASA4, PSME3, PSMD14 |
875 | GO:0046883 | 0.00 | 2.93 | 26.84 | 50 | 92 | regulation of hormone secretion | SLC25A4, ANXA1, ANXA5, ARL2, ARNTL, CACNA1A, CHRM3, CNR1, CRHBP, EFNA5, ENSA, EPHA5, GDF9, GHSR, GNAS, FFAR3, HMGCR, FOXA2, HTR2C, IFNG, ITPR1, ITPR3, KCNA5, KCNC2, KCNJ11, KCNS3, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PTGS1, RAP1A, REST, RFX3, SLC2A2, SNAP25, SREBF1, SYT5, TACR2, FGF23, IQGAP1, SYT7, HMGN3, NRXN1, NR1D1, CLOCK, SPCS2, NR1H4 |
876 | GO:1901987 | 0.00 | 2.93 | 10.14 | 19 | 35 | regulation of cell cycle phase transition | BIRC5, APP, CDK4, CENPE, DDB1, ERCC3, PRKCQ, RAD51C, RAD51B, SIX3, SKP1, SMARCD3, ZNF16, CUL3, CUL1, PHOX2B, MAD2L1BP, KNTC1, DLGAP5 |
877 | GO:1901654 | 0.00 | 2.93 | 13.36 | 25 | 46 | response to ketone | ADCY1, AGTR2, AQP1, ARG1, ASS1, BCL2L1, KLF9, CASP9, CPS1, DNMT3B, F7, FGA, GNAI1, GNAS, HMBS, P2RY4, P2RY6, SERPINF1, PRKAA1, PRKCE, PTAFR, CCL21, TNFSF4, KLF4, SLIT2 |
878 | GO:0007268 | 0.00 | 2.92 | 75.25 | 139 | 260 | synaptic transmission | ADCY1, ADCY7, AP2B1, AMPH, ATP1A2, ATP2B2, CACNB1, CACNB2, CACNB4, CALM3, CAMK2G, CDC20, CDH8, AP2M1, AP2S1, CLCN3, CNP, CNR1, COMT, CREB1, CRH, CRHBP, CTNND2, CX3CR1, DBH, DBI, DBN1, DLG2, DLG3, DNM1, DRD3, EGR2, EIF4EBP2, FNTA, GABRA5, GABRB2, GABRG1, GABRR1, GABRR2, GDNF, GFAP, GLRB, GNAI3, GNB2, GNG3, GNG10, GNGT1, GNGT2, GPR1, GRIA4, GRM1, HRH1, HTR2C, ITPR3, KCNA1, KCNA3, KCNA4, KCNA5, KCNC2, KCND2, KCND3, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN4, KCNQ1, KCNS1, KCNS2, KCNS3, KIF5A, KISS1, KIT, RAB8A, ATXN3, OMP, OPHN1, OXTR, P2RX1, PCDH8, PDPK1, PDYN, PRKACB, PRKCB, PRKCE, MAPK1, PTN, RAB3B, RAC1, RAC3, RAF1, RARA, RPS6KA1, RPS6KA2, RPS6KA3, RRAS, SCN2B, SLC6A2, SLC8A3, SNCB, STAU1, SYP, SYPL1, SYT5, CNTN2, NR2E1, VDAC1, YWHAH, LRP8, KCNAB1, KCNAB2, BSN, UNC119, USP14, SLC6A5, KCNAB3, GPR52, KCNK6, APBA3, GABBR2, RIN1, RAPGEF2, SNAP91, SLC12A6, HCN4, ABCC9, KCNK7, AKAP9, KCNMB2 |
879 | GO:2001237 | 0.00 | 2.92 | 9.64 | 18 | 33 | negative regulation of extrinsic apoptotic signaling pathway | CTTN, FGA, GPX1, HGF, ICAM1, IGF1, ITGA6, ITGAV, SERPINE1, RAF1, RPS6KB1, SIAH2, SCG2, PEA15, NRP1, ARHGEF2, RB1CC1, PSME3 |
880 | GO:0071453 | 0.00 | 2.92 | 23.12 | 43 | 79 | cellular response to oxygen levels | ADAM8, AQP1, ARNT, BACH1, BAD, BNIP3L, CCNB1, CLCA1, DNMT3A, DNMT3B, LPAR1, SLC29A1, EP300, GATA6, GNGT1, ICAM1, RBPJ, IRAK1, KCND2, KCNK2, KCNK3, PRKAA1, PRKCE, PTEN, PTGIS, PTGS2, PTN, RPS27A, SLC2A4, SLC8A1, SLC8A3, SLC9A1, STC1, TRPC1, TSC1, UBB, UBE2D1, UBE2D2, VEGFA, CUL2, OGT, PICK1, RBX1 |
881 | GO:0014812 | 0.00 | 2.91 | 9.66 | 18 | 33 | muscle cell migration | ANXA1, ACE, LPAR1, F3, HAS2, IGF1, IGFBP3, ILK, ITGA2, P2RY2, P2RY6, SERPINE1, RPS6KB1, SORL1, VTN, NRP1, ITGB1BP1, SLIT2 |
882 | GO:0046718 | 0.00 | 2.91 | 19.90 | 37 | 68 | viral entry into host cell | ADRBK1, ANPEP, AXL, CD4, CD86, SCARB1, SCARB2, CR1, CR2, CXADR, CD55, DPP4, EFNB2, EPS15, GYPA, ICAM1, IFNA2, ITGA2, ITGA5, ITGAV, ITGB1, ITGB5, KPNA3, PVR, SELPLG, SLAMF1, SLC10A1, SLC20A2, TRIM21, DYNLT1, TYRO3, UVRAG, TRIM25, FCN3, VAMP8, CLDN1, XPR1 |
883 | GO:0002381 | 0.01 | 2.91 | 6.44 | 12 | 22 | immunoglobulin production involved in immunoglobulin mediated immune response | CD28, CD40, IFNG, IL10, XCL1, STAT6, TNFSF4, UNG, TNFSF13, RNF8, EXO1, IL27RA |
884 | GO:0003254 | 0.01 | 2.91 | 6.44 | 12 | 22 | regulation of membrane depolarization | TSPO, CAV3, DCN, IFI6, KDR, SMAD7, NTSR1, P2RX7, PTPN3, SCN2B, SCN5A, HCN4 |
885 | GO:0014855 | 0.01 | 2.91 | 6.44 | 12 | 22 | striated muscle cell proliferation | ANGPT1, CCNB1, CXADR, GATA4, GATA6, NRG1, RBPJ, KCNK2, SMAD1, PRKAR1A, STAT3, TP73 |
886 | GO:0016572 | 0.01 | 2.91 | 6.44 | 12 | 22 | histone phosphorylation | CCNB1, CDK2, CHEK1, PRKAA1, PRKCB, MAPK3, VRK1, RPS6KA4, BAZ1B, AURKB, RPS6KA5, VPRBP |
887 | GO:0030225 | 0.01 | 2.91 | 6.44 | 12 | 22 | macrophage differentiation | BMP4, CASP8, CASP10, CEBPE, CSF1R, HCLS1, ID2, INHA, PTPN2, RB1, VEGFA, RIPK1 |
888 | GO:0046638 | 0.01 | 2.91 | 6.44 | 12 | 22 | positive regulation of alpha-beta T cell differentiation | ADA, ANXA1, CD86, IFNG, IHH, IL12B, RARA, SYK, TNFSF4, AP3B1, RIPK2, AP3D1 |
889 | GO:0071868 | 0.01 | 2.91 | 6.44 | 12 | 22 | cellular response to monoamine stimulus | ABL1, APP, DNM2, DRD5, GNAS, ID1, KCNQ1, PDE4B, RYR2, SLC9A1, SNCA, SRD5A1 |
890 | GO:1903523 | 0.01 | 2.91 | 6.44 | 12 | 22 | negative regulation of blood circulation | ADRBK1, AGTR2, ATP1A1, ATP1A2, BMPR2, CRP, F2R, HMGCR, INS, PLN, CX3CL1, PDE5A |
891 | GO:0097285 | 0.00 | 2.91 | 33.37 | 62 | 115 | cell-type specific apoptotic process | ABL1, ABL2, ADA, ANXA1, APOH, BMP4, BMPR2, BTK, CAMK2A, CASP8, KRIT1, CD3G, CD40, CD74, CLC, COL4A3, DFFA, DNMT3A, TSC22D3, FAP, FGA, GNGT1, HCLS1, NRG1, HMGCR, ICAM1, IFNG, IGF1, IL2RA, IL10, IL12B, IL13, IDO1, KDR, KITLG, P2RX7, SERPINE1, PAX2, PDPK1, SERPINB13, PRKCQ, PTEN, RAG1, RPS6KA2, RYR2, SORT1, CCL21, SIX3, SIGLEC1, SOX9, ADAM17, SCG2, CUL3, API5, AKR1C3, RIPK1, AURKB, STK17B, STK17A, BAG3, RAPGEF2, PDCD7 |
892 | GO:0072163 | 0.00 | 2.90 | 16.68 | 31 | 57 | mesonephric epithelium development | AGTR2, ARG2, BMP4, CAT, CD44, FGF8, FOXD1, GATA3, GDNF, GPC3, ILK, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, PAX2, PSPN, PTCH1, RARA, RARB, RET, SALL1, SDC1, SDC4, SOX9, VEGFA, WNT1, WNT11, SLIT2, SPRY1 |
893 | GO:1901701 | 0.00 | 2.90 | 113.62 | 208 | 397 | cellular response to oxygen-containing compound | ADCY1, ANGPT1, ANXA1, ANXA5, APRT, ARAF, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, BAD, BCL2L1, CALM3, CAMK2A, CAMK2G, CDC6, CDK2, AKR1C4, COL6A1, CSF2RB, CSH1, CYBA, CYP11B1, DHFR, DNM2, DNMT1, DPEP1, DRD5, DUSP5, DUSP7, DUSP9, LPAR1, EFNA5, EIF4B, EIF4E, EIF4EBP2, SLC29A1, EPHA5, EPOR, ETS1, F3, FBN1, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FYN, GATA4, GCG, GCGR, GH2, GHRHR, GHSR, GNAI1, GNB2, GNG3, GNG10, GNRHR, GRB2, GRIN2A, HGF, NRG1, HMGCR, NR4A1, FOXA2, ID1, IGF1R, IGF2, IL1R1, IL2RA, IL2RB, IL2RG, IL3, INS, KCNC2, KCNJ11, KIT, IPO5, MARK3, RAB8A, MEN1, KITLG, FOXO4, YBX1, NTRK2, OXCT1, P2RX4, P2RY11, PRDX1, PDPK1, PIK3C2A, PPP5C, PRKAB2, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCB, PRKCI, PRKCQ, PRL, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTGS2, PTK2, PTPN2, PTPN6, PTPRA, PTPRE, PTPRN, PTPRN2, PYCR1, RAF1, RANGAP1, RASA2, RHEB, RPS3, RPS6, RPS6KA2, RPS6KB1, RPS27A, RXRA, RYR2, SRSF5, SHC1, SHMT1, SIPA1, SLC2A4, SLC2A5, SLC9A1, SMARCA4, SMARCC1, SNCA, SOD2, SOD3, SOX4, SPTA1, SPTB, SRF, STAT3, STAT5B, STAT6, ADAM17, PRDX2, KLF10, HSP90B1, TRAF2, TSC1, UBB, USF1, TRPV1, WNT1, ZNF16, CUL3, PIK3R3, PEA15, ATP6V0E1, SOCS3, RGN, ATP6V0D1, IL1RL1, ARHGEF2, RAB11B, HMGN3, GLP2R, SLIT2, KL, NRXN1, PSMF1, NRG2, ATP6V1G1, BCAR1, C2CD5, RBX1, HDAC6, IL18BP, TRAP1, RASA4, PSME3, PSMD14 |
894 | GO:0002791 | 0.00 | 2.90 | 24.79 | 46 | 85 | regulation of peptide secretion | SLC25A4, ANXA5, ARL2, ARNTL, CACNA1A, CD74, CHRM3, CNR1, CRHBP, EFNA5, ENSA, EPHA5, GHSR, GNAS, FFAR3, HMGCR, FOXA2, HTR2C, IFNG, ITPR1, ITPR3, KCNA5, KCNC2, KCNJ11, KCNS3, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, RAP1A, REST, RFX3, SLC2A2, SNAP25, SREBF1, SYT5, IQGAP1, SYT7, HMGN3, NRXN1, NR1D1, CLOCK, SPCS2, NR1H4 |
895 | GO:0042752 | 0.00 | 2.89 | 10.23 | 19 | 35 | regulation of circadian rhythm | ADA, ADCY1, ALB, ARNTL, CHRNB2, CREB1, CRH, CSNK1D, DRD3, GHRHR, PRKAA1, PROX1, SFPQ, KLF10, TOP2A, UBE3A, PER3, NR1D1, NR1D2 |
896 | GO:0071356 | 0.00 | 2.88 | 11.28 | 21 | 39 | cellular response to tumor necrosis factor | ASS1, ENTPD2, CD58, COL1A1, CRHBP, CYBA, GATA3, KAT2A, HAS2, ICAM1, KCNJ11, NTRK2, CCL21, CCL22, CCL25, XCL1, CX3CL1, XCL2, TRPV1, ARHGEF2, IL18BP |
897 | GO:0006144 | 0.01 | 2.87 | 7.02 | 13 | 24 | purine nucleobase metabolic process | ACPP, ADA, ADSS, AMPD1, AMPD2, APRT, CAT, GPX1, HPRT1, IMPDH1, IMPDH2, PFAS, SHMT1 |
898 | GO:0010862 | 0.01 | 2.87 | 7.02 | 13 | 24 | positive regulation of pathway-restricted SMAD protein phosphorylation | ACVR1B, ACVRL1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, GDF9, INHA, TTK, BMP15, GDF15 |
899 | GO:0034394 | 0.01 | 2.87 | 7.02 | 13 | 24 | protein localization to cell surface | ANGPT1, CAV3, EMP2, FGF7, GPM6B, NRG1, USP4, VCL, WNT11, KCNAB2, RAB11B, PIGK, PTPRU |
900 | GO:0006303 | 0.00 | 2.86 | 10.83 | 20 | 37 | double-strand break repair via nonhomologous end joining | BARD1, SETMAR, SUMO1, UVRAG, XRCC5, HIST1H4I, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HERC2, RNF8, BRE, DCLRE1A, RAD50, PSMD14 |
901 | GO:0002819 | 0.00 | 2.86 | 18.44 | 34 | 63 | regulation of adaptive immune response | ADA, ANXA1, BTK, C3, CD4, CD28, CD40, CLC, CR1, FCER1A, FCER2, HPX, IFNA2, IFNG, IL10, IL12B, IRF1, P2RX7, PRKCQ, PTPN6, PVR, XCL1, STAT6, TRAF2, TNFSF4, UNG, WAS, ZP3, FZD5, TNFSF13, RIPK2, TNFSF18, IL1RL1, IL27RA |
902 | GO:0071478 | 0.01 | 2.85 | 7.57 | 14 | 26 | cellular response to radiation | BCL2L1, CRYAB, CYBA, DNM2, ELK1, GATA3, GRB2, IFI16, ITGB1, MGMT, RAD51, WRN, XRCC5, CLOCK |
903 | GO:0000187 | 0.00 | 2.84 | 19.02 | 35 | 65 | activation of MAPK activity | ADAM8, ALK, CD74, CSPG4, DUSP5, DUSP7, DUSP9, LPAR1, EFNA1, ERCC6, FCER1A, FPR1, GNG3, GRM1, HGF, IRAK1, IRAK2, ITGA1, KIT, MAP3K11, NTRK3, P2RX7, PRKAA1, MAPK1, MAPK3, RPS27A, SHC1, SYK, TP73, UBB, IKBKG, MADD, PEA15, RIPK1, RIPK2 |
904 | GO:0006415 | 0.00 | 2.84 | 19.02 | 35 | 65 | translational termination | EIF5A, FAU, UPF1, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, RPL14, RPL23 |
905 | GO:0060548 | 0.00 | 2.84 | 120.82 | 218 | 416 | negative regulation of cell death | ABL1, ABL2, ADA, ADAR, ADCYAP1R1, ALB, SLC25A4, ANXA1, ANXA4, ANXA5, APBB2, BIRC3, XIAP, BIRC5, APOH, AQP1, ARAF, ARF4, ASCL1, ASNS, BAD, BARD1, BCL2A1, BCL3, BLK, BMP4, BNIP3L, CASP8, CAT, CBL, KRIT1, CD44, CD59, CD74, CDKN1A, CDKN2D, CLU, COL2A1, COMP, CRH, CRYAB, CSF1R, CSF2, CSNK2A1, CTGF, CTH, CTNNA1, CTSH, CX3CR1, DAD1, DDB1, DDX3X, DFFA, DPEP1, TSC22D3, DUSP1, EDNRA, EDNRB, EGR3, CTTN, FGA, FGF4, FLT4, IFI6, GATA3, GATA6, GCG, GLO1, GPX1, GRINA, HCLS1, HGF, NRG1, HMGCR, HPN, HSPA9, HSPB1, ICAM1, ID1, IFIT3, IGF1R, IHH, IL1A, IL2RB, IL10, IDO1, ING2, INS, IRAK1, ITGA6, ITGA5, ITGAV, ITGB1, KCNJ1, KDR, KIT, LTF, MAD2L1, SMAD3, SMAD6, KITLG, MGMT, YBX1, NTRK3, NTSR1, OPA1, PA2G4, SERPINE1, PAX2, PDK4, PDPK1, SERPINB9, SERPINB13, PIM1, PRKAA1, PRKD1, PRKCQ, DNAJC3, PROC, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, PYCR1, RAF1, RAG1, RARA, RARB, RPS3A, RPS6KA1, RPS6KA3, RPS6KB1, RPS27A, CCL21, CX3CL1, SGK1, SIAH2, STIL, SLC9A1, SNAI1, SOX4, SOX9, SOX10, SOX11, STAT5B, SUPV3L1, NR2E1, TPT1, HSP90B1, UBB, UNG, VDAC2, VEGFA, VIL1, VIP, WNT1, WNT11, YWHAZ, ZNF16, SCG2, FZD3, OGT, API5, MADD, TP63, PEA15, TRADD, RIPK1, TNFSF14, TNFSF10, RIPK2, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, WISP3, VNN1, TAX1BP1, TNFSF18, SOCS3, RGN, ARHGEF2, AURKB, KLF4, EIF2AK3, ATG5, PSMF1, BAG5, BAG4, BAG3, RB1CC1, AREL1, NR1H4, TRAP1, PSME3, DHRS2, PSMD14 |
906 | GO:0043200 | 0.00 | 2.84 | 15.20 | 28 | 52 | response to amino acid | ALAD, ARG1, ASNS, ASS1, BAD, BCL2L1, CDO1, CHUK, COL1A1, COL6A1, CPS1, CREB1, CTGF, CYBA, DNMT1, DNMT3A, DNMT3B, GLRA1, GLRB, GSS, HMBS, HMGCS2, ICAM1, IPO5, LIPC, NTRK2, PTN, RPS6KB1 |
907 | GO:0030324 | 0.00 | 2.84 | 23.95 | 44 | 82 | lung development | ACVR2B, ADA, ARG1, ASCL1, BMPR1A, BMPR2, CREB1, CRH, CTGF, CYP1A2, DHCR7, EIF4E, EP300, FGF9, FGFR3, GATA6, GPC3, HMGCS2, HSD11B1, RBPJ, IL13, KDR, LIPA, LTA4H, NUMA1, PGR, PPP1CA, PROX1, PTN, RAB3A, SFTPD, SIM2, SP1, SP3, SPARC, SREBF1, VEGFA, WNT11, AIMP2, IFT88, NUMB, ADAMTS2, PHF14, ADAMTSL2 |
908 | GO:0043299 | 0.01 | 2.84 | 7.60 | 14 | 26 | leukocyte degranulation | FCER1A, FGR, IL13, IL13RA2, KIT, PDPK1, RAB27A, RAC2, S100A13, LAT2, VAMP8, SNAP23, CD84, GAB2 |
909 | GO:0071326 | 0.00 | 2.83 | 19.61 | 36 | 67 | cellular response to monosaccharide stimulus | BAD, CRH, CYBA, EFNA5, SLC29A1, EPHA5, GATA4, GCG, GHRHR, GPLD1, HMGCR, FOXA2, ICAM1, IGF1, IGF1R, IL1R1, KCNJ11, MEN1, OXCT1, PAX2, SERPINF1, PRKCE, PTPRN, PTPRN2, RAF1, RAP1A, SLC2A5, SMARCA4, SOX4, SRF, OGT, RAB11B, HMGN3, NRXN1, NR1D1, NR1H4 |
910 | GO:0051193 | 0.01 | 2.83 | 7.61 | 14 | 26 | regulation of cofactor metabolic process | ARNT, BPGM, DLD, IGF1, INS, P2RX7, PDK4, PGAM1, PRKAA1, PRKAG1, SNCA, STAT3, PDHX, OGT |
911 | GO:1990090 | 0.01 | 2.83 | 7.61 | 14 | 26 | cellular response to nerve growth factor stimulus | APP, CREB1, CSNK1D, DNMT1, KAT2A, RAPGEF1, ID1, NTRK2, RAP1A, RPS3, SORT1, TRPV1, RAPGEF2, EIF4A3 |
912 | GO:0001568 | 0.00 | 2.83 | 74.92 | 136 | 257 | blood vessel development | ACTA2, ADAM8, AHR, ANG, ANGPT1, ANGPT2, ANPEP, ANXA3, APOH, KLK3, AQP1, ADGRB2, BAX, KLF5, C3, CASP8, KRIT1, CDX2, CCR3, COL1A1, COL4A3, COL15A1, CRKL, CSPG4, CTGF, CTSH, CX3CR1, DCN, DHCR7, TYMP, ECM1, S1PR1, EDNRA, EFNA1, EFNB2, EGR3, EPHA2, ELK3, EMP2, ENPEP, EPHB1, EPHB2, EPHB3, ETS1, ETV2, F3, PTK2B, FAP, FGF6, FGF9, FLT1, FLT4, GATA4, GATA6, B4GALT1, GJA4, GPC3, GPI, GPLD1, GPX1, RAPGEF1, GTF2I, HAS2, HGF, HHEX, NR4A1, HRG, HSPB1, ID1, IHH, IL1A, IL18, ISL1, ITGA5, ITGA7, ITGAV, ITGB1, JUN, KDR, MEOX2, MFGE8, FOXO4, NRCAM, NTRK2, SERPINE1, PCSK5, SERPINF1, PRCP, PRKCB, PRKD1, PRKX, PTEN, PTGIS, PTGS2, PTK2, PTN, PTPRJ, RAP1A, RRAS, S100A7, SAT1, CX3CL1, SHB, SHC1, SP100, SPARC, SRPK2, SYK, T, TAL1, NR2E1, TNFAIP2, TNNI3, VEGFB, VEZF1, SCG2, FZD4, FZD8, SERPINB7, TNFSF12, ADAM15, NRP2, SGPL1, ITGB1BP1, KLF4, SLIT2, NRXN3, NRXN1, HAND1, EIF2AK3, RAPGEF2, SEMA3E, CUL7, SLC12A6, PDCD6, WASF2 |
913 | GO:0042593 | 0.00 | 2.82 | 33.36 | 61 | 114 | glucose homeostasis | ADRA1B, BAD, CAV3, CNR1, CRH, CRY2, CYBA, CYP11B1, DBH, DHPS, EFNA5, SLC29A1, EPHA5, G6PC, GATA4, GCG, GCGR, GHRHR, GPLD1, FFAR1, HK2, HMGCR, FOXA2, ICAM1, IGF1, IGF1R, IL1R1, INS, KCNJ11, MEN1, OAS1, OXCT1, PAX2, PCK1, PDK4, SERPINF1, PRCP, PRKAA1, PRKCE, PTCH1, PTPN2, PTPRN, PTPRN2, RAF1, RANBP2, RAP1A, RPS6, SLC2A4, SMARCA4, SOX4, SRF, STAT3, HNF1A, USF1, WFS1, OGT, RAB11B, HMGN3, NRXN1, NR1D1, NR1H4 |
914 | GO:0022037 | 0.00 | 2.82 | 15.80 | 29 | 54 | metencephalon development | ABAT, ABL1, ABL2, AGTR2, ARCN1, PHOX2A, ASCL1, RERE, ATP2B2, CACNA1A, CDK5, LPAR1, KAT2A, GRID2, OGDH, OTX1, OTX2, PROX1, PTN, PTPRS, RFX4, SCN5A, NR2C2, WNT1, USP9X, FZD4, ATRN, NRXN1, SLC4A7 |
915 | GO:0051098 | 0.00 | 2.82 | 20.71 | 38 | 71 | regulation of binding | ABL1, ABL2, ADD1, ANGPT1, APLP2, APP, ATR, BCL3, BMP4, KRIT1, CDK5, CEBPG, EP300, EPB41, EPHA4, GATA3, GCG, KAT2A, NRG1, IGF1, ITGA2, SMAD3, MEN1, RAN, RARA, RFNG, SMARCD3, SPTA1, TRAF2, VTN, NRP1, ARHGEF7, TNFSF18, CCPG1, KLF4, EIF2AK3, TRAF4, RAPGEF2 |
916 | GO:0044409 | 0.00 | 2.82 | 20.19 | 37 | 69 | entry into host | ADRBK1, ANPEP, AXL, CD4, CD86, SCARB1, SCARB2, CR1, CR2, CXADR, CD55, DPP4, EFNB2, EPS15, GYPA, ICAM1, IFNA2, ITGA2, ITGA5, ITGAV, ITGB1, ITGB5, KPNA3, PVR, SELPLG, SLAMF1, SLC10A1, SLC20A2, TRIM21, DYNLT1, TYRO3, UVRAG, TRIM25, FCN3, VAMP8, CLDN1, XPR1 |
917 | GO:0051806 | 0.00 | 2.82 | 20.19 | 37 | 69 | entry into cell of other organism involved in symbiotic interaction | ADRBK1, ANPEP, AXL, CD4, CD86, SCARB1, SCARB2, CR1, CR2, CXADR, CD55, DPP4, EFNB2, EPS15, GYPA, ICAM1, IFNA2, ITGA2, ITGA5, ITGAV, ITGB1, ITGB5, KPNA3, PVR, SELPLG, SLAMF1, SLC10A1, SLC20A2, TRIM21, DYNLT1, TYRO3, UVRAG, TRIM25, FCN3, VAMP8, CLDN1, XPR1 |
918 | GO:0052192 | 0.00 | 2.82 | 20.19 | 37 | 69 | movement in environment of other organism involved in symbiotic interaction | ADRBK1, ANPEP, AXL, CD4, CD86, SCARB1, SCARB2, CR1, CR2, CXADR, CD55, DPP4, EFNB2, EPS15, GYPA, ICAM1, IFNA2, ITGA2, ITGA5, ITGAV, ITGB1, ITGB5, KPNA3, PVR, SELPLG, SLAMF1, SLC10A1, SLC20A2, TRIM21, DYNLT1, TYRO3, UVRAG, TRIM25, FCN3, VAMP8, CLDN1, XPR1 |
919 | GO:0060349 | 0.00 | 2.81 | 12.00 | 22 | 41 | bone morphogenesis | BMP4, BMPR2, RUNX2, COL1A1, COL2A1, COL9A1, COL10A1, COMP, DLX5, FGF4, FGFR3, GNAS, HAS2, INPPL1, INSIG1, LTF, PEX7, RARA, RARB, SOX9, STC1, T |
920 | GO:0030073 | 0.04 | 2.81 | 4.34 | 8 | 15 | insulin secretion | ACVR2B, ANXA1, CAMK2G, IL1RN, STXBP3, HNF1A, EIF2AK3, RIMS2 |
921 | GO:0007267 | 0.00 | 2.81 | 74.37 | 136 | 264 | cell-cell signaling | ACVR2B, ADAM10, ADRA1B, AGTR1, AGTR2, SLC25A4, ANXA1, ANXA5, AQP1, ARL2, ARNTL, ASIP, BAD, BLK, BMP3, BMP4, BST2, CD86, TNFSF8, CD70, ADGRE5, CCR1, CTF1, CTGF, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EFNB2, ENPEP, ENSA, EPHA5, FGA, FGF3, FGF4, FGF6, FGF7, FGF9, FGF11, FGFR3, FZD2, GALR1, GATA3, GATA4, GCG, GDF9, GHRHR, GHSR, GJA3, GJA4, GJB1, GJB2, GLUD1, GNAS, GPLD1, FFAR1, FFAR3, GRB2, HGF, HMGCR, FOXA2, IAPP, IFNA2, IHH, IK, IL1RN, IL3, IL10, IL13, IL18, INHA, INS, ISL1, ITPR1, NTF4, OXCT1, PCSK5, PGR, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PSMD9, PTH, PTGS1, PTPRN, RAB1A, REST, RFX3, S100A9, CCL21, CCL22, CXCL6, CXCL5, XCL1, SLC2A2, SOX4, SOX11, SREBF1, STXBP3, HNF1A, KLF10, TRH, TRPM2, VIP, VIPR2, WNT1, SEMA3B, FGF23, FZD4, LTBP4, NR0B2, TP63, VAMP8, TNFSF10, TNFSF9, IQGAP1, NRP1, WISP3, ARHGEF7, TNFSF18, SYT7, RAB11B, HMGN3, GRAP2, EIF2AK3, GDF15, CXCL14, NR1D1, CLOCK, SPCS2, NR1H4, FGFBP1, CHST4 |
922 | GO:0050768 | 0.04 | 2.81 | 4.34 | 8 | 15 | negative regulation of neurogenesis | BMPR1A, CTNNA1, NRG1, PCM1, SORL1, STAT3, DYNLT1, ARHGEF2 |
923 | GO:0046651 | 0.00 | 2.81 | 8.71 | 16 | 30 | lymphocyte proliferation | CD151, CLC, FLT3, FYN, HPRT1, IMPDH1, IMPDH2, IRF1, ITGAD, LMO1, P2RX7, RAC2, SATB1, SOS2, TNFSF14, TNFSF18 |
924 | GO:0019233 | 0.00 | 2.80 | 12.56 | 23 | 43 | sensory perception of pain | AQP1, BDKRB1, CDK5, CHRNB2, CNR1, DLG2, EDNRA, EPHB1, FYN, IAPP, IL12B, ITGA2, KCNA1, KCND2, P2RX4, P2RX7, P2RY2, PENK, MAPK1, MAPK3, PTGS1, PTGS2, TRPV1 |
925 | GO:0006112 | 0.00 | 2.80 | 30.73 | 56 | 105 | energy reserve metabolic process | ACACB, ADCY1, ADCY7, ADRA1B, SLC25A4, ARL2, CACNA1A, CALM3, CHRM3, CPS1, G6PC, GAA, GCG, GCGR, GNAS, GNB2, GNG3, GNG10, FFAR1, GYS2, IGF1, IGF2, INS, ITPR1, ITPR3, KCNC2, KCNJ11, KCNS3, PHKA2, PHKB, PHKG1, PPP1CA, PPP1R3C, PPP2R5D, PRKAB2, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PTH, PYGB, PYGM, RAP1A, RPS27A, SLC2A2, SNAP25, SYT5, UBB, DYRK2, IQGAP1, STBD1, KL, NR1D1, EPM2AIP1 |
926 | GO:0002312 | 0.01 | 2.80 | 8.19 | 15 | 28 | B cell activation involved in immune response | ABL1, ADA, BCL3, CD28, CD40, PTK2B, IFNG, IL10, STAT6, TNFSF4, UNG, TNFSF13, RNF8, EXO1, IL27RA |
927 | GO:0006833 | 0.01 | 2.80 | 8.19 | 15 | 28 | water transport | ADCY1, ADCY7, AQP1, AQP5, AQP6, AVPR2, GNAS, HAS2, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, UPK3A |
928 | GO:0043550 | 0.01 | 2.80 | 8.19 | 15 | 28 | regulation of lipid kinase activity | EPHA8, PTK2B, FGFR3, FGR, FLT1, FLT3, KIT, PTK2, RAC1, RB1, RBL2, CCL21, PIK3R3, KLF4, RUBCN |
929 | GO:1903307 | 0.01 | 2.80 | 8.19 | 15 | 28 | positive regulation of regulated secretory pathway | ARF1, CDK5, FCER1A, FGR, GLRA1, IL13, PTAFR, RAB3A, RAB27A, SYK, SYT1, ZP3, VAMP8, SYT7, GAB2 |
930 | GO:0097530 | 0.00 | 2.80 | 16.97 | 31 | 58 | granulocyte migration | ADAM8, ANXA1, CD74, CMKLR1, CXADR, EDNRA, CXCL2, CXCL3, HRH1, IFNG, ITGA1, ITGA9, PDE4B, RAC1, RAC2, S100A7, S100A8, S100A9, S100A12, CCL21, CCL22, CCL25, XCL1, CX3CL1, XCL2, SYK, VAV1, VEGFA, SCG2, TNFSF18, SLIT2 |
931 | GO:0015696 | 0.04 | 2.79 | 4.36 | 8 | 15 | ammonium transport | ADA, CACNA1A, EDNRA, SEC14L1, TACR2, TAF7, VAMP8, SNAP23 |
932 | GO:0023056 | 0.00 | 2.79 | 11.25 | 21 | 41 | positive regulation of signaling | CHRNB2, CHRNB4, CX3CR1, DBI, DNM1, GFAP, ITGA2, ITPR3, OXTR, PTN, RAB3B, SLC8A3, SNAP25, SNCA, STAU1, SYT1, TACR2, NR2E1, TNR, SYNJ1, RAMP3 |
933 | GO:0051048 | 0.04 | 2.79 | 4.37 | 8 | 15 | negative regulation of secretion | ADA, ANPEP, AVPR2, CD74, COMT, NRG1, OXTR, CYP4F2 |
934 | GO:0007626 | 0.00 | 2.78 | 14.22 | 26 | 49 | locomotory behavior | ABAT, ADRA1B, ALDH1A3, APLP2, ASTN1, ATP2B2, CACNA1B, CHRNB2, CHRNB4, DBH, DRD3, ETV5, GAA, GRM1, HEXB, NRG1, HPRT1, HTR2C, IDO1, PEX13, SEPP1, SNAP25, STRN, TAL1, FZD4, RCAN2 |
935 | GO:0050878 | 0.00 | 2.78 | 110.11 | 197 | 378 | regulation of body fluid levels | ABL1, ACTB, ACTN4, ACTN1, ADA, ADCY1, ADCY7, APLNR, ALB, ANGPT1, ANGPT2, APP, APRT, AQP1, AQP5, ATP2A1, ATP2B1, ATP2B2, ATP2B3, AVPR2, AXL, BSG, C3, DAGLA, CALM3, CD9, ENTPD2, CD40, CD44, CD58, CD59, CD63, CD74, CDK2, CDK5, CDO1, CENPE, CHRM1, CHRM3, CHUK, CLU, COL1A1, COPA, CREB1, CSRP1, CXADR, CYBA, DGKB, DHODH, EDNRB, CELSR2, EMP2, SLC29A1, EPHB2, F2RL2, F10, FBLN1, FGR, FYN, GATA3, GATA4, GATA6, GHRHR, GNA15, GNAI1, GNAI3, GNAQ, GNAS, GP9, GPI, GRB2, GRB7, GUCA2B, H3F3B, HAS2, HBD, HBE1, HGF, HK2, HSPB1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IGF1, IGF2, ILK, ITGA6, IRF1, ITGA1, ITGA2, ITGA4, ITGA5, ITGAL, ITGAM, ITGAV, ITGB1, ITPR1, ITPR3, KCNN4, KIF5A, KRT16, LAMP2, OLR1, OXTR, P2RX1, P2RY2, PAM, SERPINA5, PDPK1, PF4V1, PRCP, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCB, PRKCE, MAPK1, MAPK3, PRL, PSAP, PTK2, PTPN6, RAB5A, RAB27A, RAC1, RAC2, RAD51C, RAD51B, RAF1, RAP1A, RAP2B, SCNN1A, SCNN1B, SCNN1G, CX3CL1, SELE, SELL, SELPLG, SHC1, SLC8A1, SLC8A3, SLC22A2, SPARC, SRF, STAT5B, STXBP3, TP73, TRPC1, TRPC3, TUBA4A, TYRO3, NR1H2, VAV1, VCL, VDR, VEGFA, VEGFB, VIP, WAS, WFS1, YWHAZ, LRP8, MAFK, SLC7A5, AKAP1, FZD6, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, DGKE, CYP4F2, AP3B1, TP63, PDE5A, VAMP8, CD84, PROZ, HIST1H3F, DOK2, CLDN1, DGKI, KIF3B, EIF2AK3, ATG5, BCAR1, GNA14, MFN2, WDR1, RASGRP2, KCNMB2, ABCC4 |
936 | GO:0048857 | 0.04 | 2.78 | 4.38 | 8 | 15 | neural nucleus development | ALDH1A3, PHOX2A, ASCL1, CACNA1A, CHRNB2, KCNC2, PHOX2B, SLC4A7 |
937 | GO:0033077 | 0.00 | 2.78 | 13.17 | 24 | 45 | T cell differentiation in thymus | ADA, ADAM8, BMP4, ZFP36L2, CD3D, CD3E, CD28, CD74, CDK6, EGR3, GATA3, IHH, PTPN2, RAG1, RAG2, SOS2, SRF, STAT5B, ADAM17, WNT1, FZD5, FZD7, FZD8, VNN1 |
938 | GO:0038096 | 0.00 | 2.78 | 13.17 | 24 | 45 | Fc-gamma receptor signaling pathway involved in phagocytosis | ABL1, ACTB, CD3G, FCGR2A, FGR, FYN, GRB2, ITPR1, ITPR3, LIMK1, PRKCE, MAPK1, MAPK3, PTK2, RAC1, SYK, VAV1, WAS, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, WASF2 |
939 | GO:0045453 | 0.04 | 2.77 | 4.38 | 8 | 15 | bone resorption | TPP1, CTSK, PTK2B, IHH, PTH, RAC1, RAC2, GPR55 |
940 | GO:0002718 | 0.00 | 2.77 | 8.78 | 16 | 30 | regulation of cytokine production involved in immune response | ANGPT1, BST2, BTK, CD36, CD74, CLC, FFAR3, IFNA2, IL10, XCL1, TRAF2, TNFSF4, FZD5, SEMA7A, ATG5, TRIL |
941 | GO:0007405 | 0.00 | 2.77 | 8.78 | 16 | 30 | neuroblast proliferation | ASCL1, DAGLA, CTNNA1, CX3CR1, DCT, EML1, KCNA1, CX3CL1, SIX3, SMARCD3, SOX5, SOX10, VEGFA, FZD3, FZD9, NUMB |
942 | GO:0014897 | 0.00 | 2.77 | 8.78 | 16 | 30 | striated muscle hypertrophy | AGTR2, CAV3, GATA4, GATA6, IGF1, P2RX4, RYR2, SLC9A1, TRPC3, COL14A1, AKAP1, SORBS2, PDE5A, CTDP1, AKAP6, KDM4A |
943 | GO:0045685 | 0.04 | 2.77 | 4.38 | 8 | 15 | regulation of glial cell differentiation | BIN1, EPHA4, F2, FGFR3, NTRK3, CNTN2, NR2E1, RNF112 |
944 | GO:0010720 | 0.03 | 2.77 | 4.92 | 9 | 17 | positive regulation of cell development | ATP6AP1, BAD, BAX, B4GALT1, PROC, RFX3, VDR, PDE5A, AKAP6 |
945 | GO:0000303 | 0.04 | 2.77 | 4.39 | 8 | 15 | response to superoxide | CD36, DHFR, ERCC6, PRDX1, SOD2, SOD3, PRDX2, RGN |
946 | GO:0003016 | 0.04 | 2.77 | 4.39 | 8 | 15 | respiratory system process | ADH5, ATP1A2, GAA, GLRA1, RAB3A, TNNC1, KDM6A, PHOX2B |
947 | GO:0003197 | 0.04 | 2.77 | 4.39 | 8 | 15 | endocardial cushion development | BMP4, BMPR1A, ERG, FGF8, GATA4, RBPJ, ISL1, SOX9 |
948 | GO:0006706 | 0.04 | 2.77 | 4.39 | 8 | 15 | steroid catabolic process | STS, SCARB1, CYP1A2, CYP3A4, CYP27B1, YWHAH, FGF23, SNX17 |
949 | GO:0010659 | 0.04 | 2.77 | 4.39 | 8 | 15 | cardiac muscle cell apoptotic process | APAF1, CAMK2A, GNGT1, NRG1, HMGCR, ILK, PDPK1, RPS6KA2 |
950 | GO:0016338 | 0.04 | 2.77 | 4.39 | 8 | 15 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules | CLDN3, CLDN11, CX3CL1, CLDN12, CLDN10, CLDN8, CLDN6, CLDN1 |
951 | GO:0030199 | 0.04 | 2.77 | 4.39 | 8 | 15 | collagen fibril organization | COL1A1, COL2A1, COL11A1, DDR2, P4HA1, COL14A1, ADAMTS3, ADAMTS2 |
952 | GO:0034199 | 0.04 | 2.77 | 4.39 | 8 | 15 | activation of protein kinase A activity | ADCY1, ADCY7, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B |
953 | GO:0035813 | 0.04 | 2.77 | 4.39 | 8 | 15 | regulation of renal sodium excretion | AGTR1, AGTR2, ANPEP, AVPR2, COMT, DRD3, EDNRB, KNG1 |
954 | GO:0042119 | 0.04 | 2.77 | 4.39 | 8 | 15 | neutrophil activation | ANXA3, BCR, PTAFR, STXBP2, STXBP3, SYK, TYROBP, STX11 |
955 | GO:0042776 | 0.04 | 2.77 | 4.39 | 8 | 15 | mitochondrial ATP synthesis coupled proton transport | ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J |
956 | GO:0043555 | 0.04 | 2.77 | 4.39 | 8 | 15 | regulation of translation in response to stress | ATF4, PPP1CA, DNAJC3, RBM4, RPS6KA1, RPS6KA3, EIF2B3, EIF2AK3 |
957 | GO:0050873 | 0.04 | 2.77 | 4.39 | 8 | 15 | brown fat cell differentiation | INS, ITGA6, PTGS2, SLC2A4, UCP1, PEX11A, ZNF516, ARL4A |
958 | GO:0060669 | 0.04 | 2.77 | 4.39 | 8 | 15 | embryonic placenta morphogenesis | GRB2, IL10, ITGA4, LLGL2, ST14, FZD5, SOCS3, TRIM28 |
959 | GO:0061615 | 0.04 | 2.77 | 4.39 | 8 | 15 | glycolytic process through fructose-6-phosphate | ALDOC, ENO2, GAPDH, GPI, HK2, PFKFB4, PGAM1, PPP2R5D |
960 | GO:0061621 | 0.04 | 2.77 | 4.39 | 8 | 15 | canonical glycolysis | ALDOC, ENO2, GAPDH, GPI, HK2, PFKFB4, PGAM1, PPP2R5D |
961 | GO:0071514 | 0.04 | 2.77 | 4.39 | 8 | 15 | genetic imprinting | DNMT3A, DNMT3B, GNAS, IGF2, KCNQ1, EED, DIRAS3, TRIM28 |
962 | GO:2000171 | 0.04 | 2.77 | 4.39 | 8 | 15 | negative regulation of dendrite development | DCC, EFNA1, ID1, PTEN, PTPRZ1, YWHAH, RAPGEF2, KIAA0319 |
963 | GO:0010952 | 0.00 | 2.76 | 23.71 | 43 | 81 | positive regulation of peptidase activity | APAF1, APP, BAD, BAX, BOK, CASP8, CASP9, CD14, COL4A3, CR1, CTGF, CTSH, DDX3X, F2R, F3, FBLN1, HIP1, IFI16, SMAD3, P2RX1, PCOLCE, REST, RET, RPS3, S100A8, S100A9, SNCA, TRAF2, PICALM, TRADD, RIPK1, CRADD, TNFSF10, TNFRSF10B, TNFRSF10A, EIF2AK3, PPM1F, TNFSF15, CASP8AP2, PDCD6, BCL2L11, PSME3, PSMD14 |
964 | GO:0051704 | 0.00 | 2.76 | 71.12 | 130 | 260 | multi-organism process | ABCA1, ABL1, ACTA2, ADH5, ALAD, ANXA3, KLK3, ASS1, ATP4B, BCL3, BCR, BDKRB1, BPI, TSPO, CASP9, CD6, CD8A, CD14, TNFRSF8, TNFSF8, ENTPD2, CD40, CDK6, CEBPE, CHRNB2, CHUK, CLU, CNP, CPS1, CRP, CSF2, CYP1A2, DCN, DDX1, COCH, DNMT1, DRD3, EIF4EBP2, F2R, F3, FCN2, FGA, FGR, GATA3, GRID1, CXCL2, CXCL3, HMGCS2, HP, HRG, HSPB1, IFIT3, IFNA5, IFNA13, IFNA17, IFNA21, IFNGR1, IFNW1, RBPJ, IL10RA, IL12RB2, IL13, TNFRSF9, IL18, IRAK1, IRAK2, IRF1, IRF5, JUND, KCNJ8, NRF1, ODC1, SERPINE1, PDE4B, PENK, PF4V1, CFP, PRG2, PRKCE, DNAJC3, PROS1, PTGER1, PTGER2, UPF1, RNASE3, RPS6KA3, S100A7, S100A8, S100A9, S100A12, CCL22, CXCL6, CXCL5, XCL1, SELE, SELP, SFTPD, SNCA, SPARC, ADAM17, NR2E1, TNFRSF1B, TPT1, TNFSF4, VIL1, FZD5, HIST1H2BF, HIST2H2BE, OGT, PPM1D, PARG, PRKRA, RIPK2, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, SOCS3, DDX21, DCLK1, NRXN3, NRXN1, NRXN2, IL27RA, ADAMTS4, LITAF, NR1D1, NR1H4, ABCC9, IL18BP |
965 | GO:0071383 | 0.00 | 2.75 | 15.94 | 29 | 55 | cellular response to steroid hormone stimulus | AGTR2, AHR, ANXA1, AQP1, ARG1, ASS1, ATP1A1, ATP1A2, ATP1A3, ATP2B1, KLF9, CASP9, CRH, CRHBP, DNMT3B, ELK1, FLT3, HMBS, HMGCS2, IL10, ITGA2, SERPINF1, SERPINB9, REST, SRD5A1, STC1, UBE2L3, AKR1C3, RAMP3 |
966 | GO:0002763 | 0.00 | 2.75 | 9.37 | 17 | 32 | positive regulation of myeloid leukocyte differentiation | ATP6AP1, CASP8, CCR1, CREB1, CSF1R, GNAS, HCLS1, ID2, IFNG, IL3, IL12B, JUN, KITLG, RB1, KLF10, OGT, RIPK1 |
967 | GO:0006301 | 0.00 | 2.75 | 9.37 | 17 | 32 | postreplication repair | DDB1, PCNA, REV3L, RFC1, RFC3, RFC4, RFC5, RPA2, RPA3, RPS27A, UBB, UBA7, UBE2V1, UFD1L, TRIM25, CUL4A, RBX1 |
968 | GO:0032481 | 0.00 | 2.75 | 9.37 | 17 | 32 | positive regulation of type I interferon production | CD14, CHUK, DDX3X, EP300, IFI16, IRAK1, IRF1, IRF5, RPS27A, TRIM21, STAT6, SYK, UBB, XRCC5, IKBKG, RIPK1, RIPK2 |
969 | GO:0035019 | 0.00 | 2.75 | 9.37 | 17 | 32 | somatic stem cell population maintenance | ASCL2, BCL9, ZFP36L2, CDX2, FGFR3, RBPJ, KIT, PAX2, RAF1, SALL1, SOX4, SOX9, STAT3, KLF10, NR2E1, CUL4A, KLF4 |
970 | GO:0035914 | 0.00 | 2.75 | 9.37 | 17 | 32 | skeletal muscle cell differentiation | ARNTL, ATF3, BCL9, KLF5, DDX5, EGR2, EMD, GPC1, HLF, RB1, SOX11, EOMES, SAP30, PHOX2B, COPS2, GTF3C5, NR1D2 |
971 | GO:1904063 | 0.00 | 2.75 | 9.37 | 17 | 32 | negative regulation of cation transmembrane transport | ATP1A2, CALM3, CASQ2, CAV3, DRD3, KCNH2, KCNQ1, NTSR1, PIK3C2A, PLN, PRKCE, SUMO1, SLC30A1, KCNAB1, SLC9A3R1, GSTO1, OXSR1 |
972 | GO:0001887 | 0.03 | 2.75 | 4.94 | 9 | 17 | selenium compound metabolic process | AHCY, CTH, DARS, EPRS, HNMT, QARS, SEPP1, AIMP2, PAPSS1 |
973 | GO:0044728 | 0.00 | 2.75 | 14.34 | 26 | 49 | DNA methylation or demethylation | ATRX, DNMT1, TRDMT1, DNMT3A, DNMT3B, GNAS, H3F3B, MGMT, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, FKBP6, ALKBH1, HIST1H3F, PICK1, TRIM28 |
974 | GO:0051223 | 0.00 | 2.75 | 23.66 | 43 | 82 | regulation of protein transport | SLC25A4, ARL2, ARNTL, BNIP3L, CACNA1A, CD40, CHRM3, CNR1, CRP, EFNA5, ENSA, EPHA5, GNAS, FOXA2, ITPR1, ITPR3, KCNA5, KCNC2, KCNS3, LLGL2, RAB8A, PAM, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PTPN14, RAP1A, RFX3, SLC2A2, SNAP25, SYT5, TRAF2, IQGAP1, SYT7, HMGN3, NRXN1, ATG5, NR1D1, CLOCK, SPCS2 |
975 | GO:0001503 | 0.00 | 2.75 | 10.98 | 20 | 38 | ossification | BMP1, BMP8B, COL2A1, COL10A1, COL11A1, CTGF, CTSK, EXT2, GPLD1, IGF2, INPPL1, PEX7, RPL38, RYR1, SORT1, SLC34A1, SP1, SP3, SPARC, STC1 |
976 | GO:0072358 | 0.00 | 2.74 | 69.39 | 125 | 242 | cardiovascular system development | ACTA2, ACVRL1, ADAM8, AHR, ANG, ANGPT1, ANGPT2, ANPEP, ANXA3, APOH, KLK3, AQP1, ADGRB2, BAX, BMPR2, KLF5, C3, KRIT1, CDX2, CCR3, COL1A1, COL4A3, COL15A1, CSPG4, CTGF, CTH, CTSH, CX3CR1, DCN, DHCR7, TYMP, ECM1, EGR3, EPHA2, ELK3, EMP2, ENPEP, EPHB1, EPHB2, EPHB3, ETS1, ETV2, F3, PTK2B, FAP, FGF6, FGF9, FLT1, FLT4, B4GALT1, GJA4, GPI, GPLD1, GPX1, RAPGEF1, GTF2I, HGF, NR4A1, HPGD, HRG, HSPB1, IGF1, IL1A, IL18, ITGA5, ITGA7, ITGAV, JUNB, KCNJ1, KCNQ1, KDR, LLGL2, MEOX2, MFGE8, FOXO4, NRCAM, NTRK2, SERPINE1, SERPINF1, PRCP, PRKCB, PRKD1, PRKX, PTGIS, PTGS2, PTPN14, RAP1A, RRAS, S100A7, SAT1, CX3CL1, SHB, SMARCA2, SP2, SP100, SRPK2, SYK, TAL1, NR2F2, NR2E1, TNFAIP2, VEZF1, FZD5, SCG2, FOSL1, FZD4, FZD8, SERPINB7, TNFSF12, NRP2, SGPL1, SOCS3, ITGB1BP1, KLF4, SLIT2, NRXN3, NRXN1, EIF2AK3, SLC4A7, RAPGEF2, SEMA3E, CUL7, SLC12A6, PDCD6, WASF2 |
977 | GO:0099536 | 0.00 | 2.74 | 119.11 | 211 | 407 | synaptic signaling | ABAT, ADCY1, ADCY7, AP2B1, AMPH, ARF1, ATP1A2, ATP2B2, BCHE, TSPO, CACNA1A, CACNA1B, CACNB1, CACNB2, CACNB4, CALM3, CAMK2A, CAMK2G, CDC20, CDH8, CDK5, CHAT, CHRM1, CHRM3, CHRNB2, CHRNB4, AP2M1, AP2S1, CLCN3, CNP, CNR1, COMT, CREB1, CRH, CRHBP, CTNND2, CX3CR1, DBH, DBI, DBN1, DLG2, DLG3, DNM1, DRD3, DRD5, DTNA, EGR2, EGR3, EIF4EBP2, SLC29A1, ETV5, PTK2B, FNTA, GABRA4, GABRA5, GABRB2, GABRG1, GABRR1, GABRR2, GAD1, GDNF, GFAP, GLRA1, GLRB, GNAI1, GNAI3, GNB2, GNG3, GNG10, GNGT1, GNGT2, GPM6B, GPR1, GRIA1, GRIA4, GRID2, GRIN2A, GRM1, HRH1, HTR2C, IFNG, ITPR3, KCNA1, KCNA3, KCNA4, KCNA5, KCNC2, KCND2, KCND3, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN4, KCNQ1, KCNS1, KCNS2, KCNS3, KIF5A, KISS1, KIT, RAB8A, ATXN3, NTRK2, NTSR1, OMP, OPHN1, OXTR, P2RX1, P2RX3, P2RX4, P2RX7, P2RY11, PCDH8, PDPK1, PDYN, PFN2, SEPT5, PPT1, PRKACB, PRKCB, PRKCE, MAPK1, PTEN, PTGS2, PTN, PTPRN2, RAB3A, RAB3B, RAB5A, RAC1, RAC3, RAF1, RAP1A, RARA, RPS6KA1, RPS6KA2, RPS6KA3, RRAS, SCN2B, CX3CL1, SLC1A6, SLC6A2, SLC6A4, SLC6A13, SLC8A3, SLC22A2, SNAP25, SNCB, SNCA, SRF, STAU1, SYN1, SYP, SYPL1, SYT1, SYT4, SYT5, TACR2, CNTN2, NR2E1, TNR, VDAC1, YWHAH, SLC30A1, LRP8, KCNAB1, SYN3, KCNAB2, STX11, SNAP23, LIN7A, SYNJ1, BSN, UNC119, USP14, SLC6A5, DGKI, KCNAB3, GPR52, SNAP29, NRXN3, NRXN1, NRXN2, KCNK6, PICK1, APBA3, GABBR2, RIN1, SNCAIP, RAPGEF2, RIMS2, EIF4A3, RIMS3, SNAP91, SLC12A6, HCN4, ABCC9, KCNK7, AKAP9, KCNMB2 |
978 | GO:0021782 | 0.03 | 2.74 | 4.96 | 9 | 17 | glial cell development | CDK5, CDK6, GFAP, ILK, S100A8, S100A9, SOX4, VIM, PICK1 |
979 | GO:0051602 | 0.03 | 2.73 | 4.97 | 9 | 17 | response to electrical stimulus | CD14, CDK2, KCNJ3, NRF1, P2RX7, RAB3A, RPS6KB1, S100A13, TACR2 |
980 | GO:0060291 | 0.00 | 2.73 | 9.95 | 18 | 34 | long-term synaptic potentiation | CREB1, CRH, CX3CR1, DBI, PTK2B, GFAP, GRIN2A, ITPR3, NTRK2, MAPK1, PTEN, PTN, SLC8A3, SNAP25, SNCA, STAU1, NR2E1, TNR |
981 | GO:0050678 | 0.03 | 2.73 | 5.51 | 10 | 19 | regulation of epithelial cell proliferation | BAX, EDNRA, EDNRB, GPX1, HMGN1, IFNG, SMAD3, PGR, SERPINB5, NR1D1 |
982 | GO:0017145 | 0.03 | 2.72 | 4.98 | 9 | 17 | stem cell division | ZFP36L2, DCT, ETV5, ING2, KIT, SOX5, FZD7, CUL3, NUMB |
983 | GO:0030818 | 0.03 | 2.72 | 4.98 | 9 | 17 | negative regulation of cAMP biosynthetic process | DRD3, LPAR1, EDNRA, EDNRB, GALR1, GNAI3, PALM, AKAP6, GABBR2 |
984 | GO:0042745 | 0.03 | 2.72 | 4.98 | 9 | 17 | circadian sleep/wake cycle | ADA, AHCY, ALB, CHRNB2, CRH, DRD3, GHRHR, SRD5A1, PER3 |
985 | GO:0046579 | 0.03 | 2.72 | 4.98 | 9 | 17 | positive regulation of Ras protein signal transduction | LPAR1, F2R, NRG1, IGF1, KITLG, RAC1, SHOC2, DGKI, GPR55 |
986 | GO:0060674 | 0.03 | 2.72 | 4.98 | 9 | 17 | placenta blood vessel development | RBPJ, JUNB, LLGL2, MAPK1, NR2F2, FZD5, FOSL1, ARID1A, SOCS3 |
987 | GO:0071305 | 0.03 | 2.72 | 4.98 | 9 | 17 | cellular response to vitamin D | ATP2B1, BGLAP, CYP27B1, ITGB1, PENK, PIM1, PTN, VDR, FGF23 |
988 | GO:0048812 | 0.00 | 2.72 | 104.19 | 185 | 359 | neuron projection morphogenesis | ACTB, ADAM10, ADCY1, AP2B1, ANGPT1, APBB1, APBB2, APP, ARAF, CACNB1, CACNB2, CACNB4, CALM3, CAMK2A, CAMK2G, CD72, CHN1, AP2M1, AP2S1, CLU, CNP, COL2A1, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2, CSF2RB, CSNK2A1, CSNK2A2, DCC, DLG3, DLX5, DNM1, DPYSL3, EPYC, DUSP5, DUSP7, DUSP9, EFNA3, EFNA4, EFNA5, EFNB1, EFNB2, EGR2, EPHA2, EPHA3, EPHA5, EPHA8, ETV1, ETV4, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, GATA3, GDI1, GDNF, GFRA1, GPC1, GPM6A, GRB2, GRIN2A, IL2RA, IL2RB, IL2RG, IL3, ISL1, ITGA1, ITGA2, ITGA5, ITGA9, ITGAV, KIF5A, KIT, MARK3, RAB8A, KITLG, NTF4, NTRK2, NTN3, OPHN1, OTX2, PAX2, PPP5C, PRKCQ, MAPK1, MAPK3, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTK2, PTPRA, RAB3A, RAC2, RAF1, RASA2, RET, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RRAS, RYK, SCN5A, ITSN1, SHC1, SIAH2, SOS2, SPTA1, SPTB, CNTN2, TBCE, DYNLT1, TOP2B, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, UGT8, FZD3, FGF23, RND2, CUL3, CNTNAP1, GAS7, UNC5C, NUMB, PEA15, ARHGEF7, PHOX2B, RPS6KA4, ARHGEF1, RPS6KA5, KL, NRXN3, NRXN1, PSMF1, NRG2, FEZ2, ARHGEF11, RBX1, RANBP9, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, AKAP9, RASA4, PSME3, PSMD14 |
989 | GO:0051351 | 0.00 | 2.72 | 21.66 | 39 | 74 | positive regulation of ligase activity | BMI1, CCNB1, CDC20, CDC27, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, RPS27A, SKP1, UBB, UBE2D1, UBE2L3, CUL1, CDC14B, CDC23, CDC16, PSMF1, PSME3, PSMD14 |
990 | GO:1904892 | 0.00 | 2.72 | 21.66 | 39 | 74 | regulation of STAT cascade | CD40, CDK5, CHAD, CSF1R, CSF2, CTF1, DCN, F2R, PTK2B, FGFR3, FLT3, FYN, GP1BA, HCLS1, HPX, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IL3, IL10, IL12B, IL13, IL18, ISL1, KIT, PPP2R1A, PRL, PTPN2, RET, TNFRSF1A, TNFRSF18, TNFSF18, SOCS3, SOCS6 |
991 | GO:0090068 | 0.00 | 2.72 | 35.63 | 64 | 122 | positive regulation of cell cycle process | ANXA1, APP, ATRX, CCNB1, CDC6, CDK2, CDK4, CDKN1A, CTGF, DDX3X, FAP, GATA6, OPN1MW, ID2, KCNA5, MAD2L1, FOXO4, ORC1, PRKCE, PROX1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RAD51C, RAD51B, OPN1LW, RPS27A, SFPQ, SMARCD3, SOX4, TP73, UBB, UBE2E2, ZNF16, RNF112, CDC45, CUL4A, TP63, CRADD, PHOX2B, AURKB, KIF3B, PSMF1, PSME3, PSMD14 |
992 | GO:0071222 | 0.00 | 2.71 | 16.64 | 30 | 57 | cellular response to lipopolysaccharide | ABCA1, ABL1, ARG1, ASS1, AXL, BYSL, TSPO, CD86, CD36, ENTPD2, CD40, CEBPE, CSF2, CX3CR1, EDNRB, HMGCS2, ICAM1, IFNG, IL10, IL12B, P2RY2, SERPINE1, PDE4B, RARA, UPF1, TNFRSF1B, TNFSF4, OGT, LITAF, NR1D1 |
993 | GO:0009952 | 0.00 | 2.71 | 16.64 | 30 | 57 | anterior/posterior pattern specification | ACVR2B, BMP4, BMPR2, CRKL, CELSR2, EMX2, EN1, ETS2, FGF8, GATA4, GPC3, HHEX, HOXC10, HOXC11, HOXD4, HOXD8, HOXD9, HOXD10, OTX1, PCSK5, RNF2, SIX3, SRF, NR2F2, TULP3, WNT1, YY1, FZD5, IFT88, ATP6AP2 |
994 | GO:0051272 | 0.00 | 2.71 | 69.65 | 124 | 238 | positive regulation of cellular component movement | ACTN4, ACVR1B, ADAM8, ADAM10, ANGPT1, ANXA3, AQP1, ARHGAP5, BDKRB1, BMP4, BMPR2, SCARB1, CD74, CCR1, CMKLR1, COL1A1, CSF1R, CTSH, DAPK3, DIAPH1, S1PR1, LPAR1, EDNRA, ETS1, F2R, F3, F7, F10, PTK2B, FBLN1, FGF7, FGR, FLT1, FLT4, FSHB, GATA3, GPLD1, GRB7, CXCL2, CXCL3, HAS2, HGF, ONECUT1, HSPB1, ICAM1, IFNG, IGF1, IGF1R, ILK, INS, ITGA2, ITGA4, ITGA5, ITGAV, ITGB1, JUN, KDR, KIT, SMAD3, KITLG, NTRK3, DDR2, P2RY2, P2RY6, SERPINE1, PF4V1, PRKCE, PRKD1, MAPK1, PROX1, PTAFR, PTGS2, PTK2, PTPRZ1, RAC1, RAC2, RET, RPS6KB1, RPS19, S100A7, CCL21, CXCL6, CXCL5, XCL1, CX3CL1, SELE, SELP, SEMA3F, SLC8A1, SNAI1, SOX9, SPARC, STAT5B, ADAM17, TRIP6, VEGFA, VEGFB, VIL1, VTN, WNT11, ZP3, PTP4A1, SEMA3B, MADCAM1, SEMA7A, IKBKAP, NUMB, TNFSF14, TNFRSF18, NRP2, NRP1, ARHGEF7, TNFSF18, ITGB1BP1, CHST3, ONECUT2, BAG4, CXCL14, BCAR1, PPM1F, RAPGEF2, SEMA3E, HDAC6, PDCD6 |
995 | GO:0042886 | 0.00 | 2.71 | 60.00 | 107 | 205 | amide transport | ABAT, ABCA1, ACVR2B, SLC25A4, ANXA1, ANXA5, AQP1, ARL2, ARNTL, BAD, BCL3, BLK, CACNA1A, CAMK2G, CD74, CHRM3, CNR1, CRH, CRHBP, EDA, EFNA5, ENSA, EPHA5, FGA, GCG, GHRHR, GHSR, GLUD1, GNAS, GPLD1, FFAR1, FFAR3, HMGCR, FOXA2, HTR2C, IFNG, IL1RN, IL10, IL12B, IL18, INS, ISL1, ITPR1, ITPR3, KCNA5, KCNC2, KCNJ11, KCNS3, KISS1, OXCT1, PRDX1, PPM1B, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRKCQ, PSMD9, PTGS2, PTPRN, PTPRN2, RAB1A, RAF1, RAP1A, REST, RFX3, S100A8, S100A9, SLC2A2, SLC15A1, SNAP25, SOX4, SREBF1, STXBP3, SYT5, TACR2, HNF1A, TRH, TRIP6, TRPM2, UPK3A, VIP, TRPV1, SLC14A2, LTBP4, NR0B2, TNFSF14, IL18R1, IQGAP1, ARHGEF7, SLC5A6, SYT7, RAB11B, HMGN3, SLC9A3R1, NRXN1, EIF2AK3, LITAF, NR1D1, CLOCK, RIMS2, SPCS2, NR1H4, COL4A3BP |
996 | GO:0007188 | 0.00 | 2.71 | 11.09 | 20 | 38 | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | AVPR2, CHRM1, CHRM3, CCR3, CNR1, S1PR1, LPAR1, FPR1, GCG, GCGR, GNAI1, GNAI3, GNAT1, GNAT2, FFAR3, PRKACB, PSAP, RGS1, GLP2R, WASF2 |
997 | GO:0008630 | 0.00 | 2.70 | 16.68 | 30 | 57 | intrinsic apoptotic signaling pathway in response to DNA damage | ABL1, BAD, BAX, BCL2A1, BCL2L1, BCL3, BOK, BRCA2, CASP9, CD44, CD74, CDKN1A, CDKN2D, CLU, EPHA2, EP300, ERCC6, HIC1, IFI16, ING2, RPS3, SNAI1, TNFRSF1A, TNFRSF1B, TP73, TPT1, XPA, DYRK2, TP63, BCL2L11 |
998 | GO:0046364 | 0.00 | 2.70 | 16.68 | 30 | 57 | monosaccharide biosynthetic process | ALDOC, ATF3, ATF4, BPGM, SLC25A10, ENO2, G6PC, GAPDH, GCG, KAT2A, GOT2, GPD2, GPI, INS, MDH2, PCK1, PCK2, PGAM1, PGD, PRKACB, PRKACG, PTPN2, RANBP2, SORD, OGT, SLC25A12, RGN, GSTO1, NR1D1, SLC25A13 |
999 | GO:0000184 | 0.00 | 2.70 | 22.83 | 41 | 78 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | FAU, EIF3E, PPP2R1A, PPP2R2A, UPF1, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, RPL14, RPL23, DHX34, EIF4A3, SMG7, RBM8A |
1000 | GO:0006940 | 0.03 | 2.70 | 5.54 | 10 | 19 | regulation of smooth muscle contraction | ATP1A2, CHRM1, CHRNB4, CNN1, DAPK3, FLT1, GHSR, P2RX1, PRKG1, TNNI3 |
1001 | GO:0044057 | 0.00 | 2.70 | 23.79 | 43 | 83 | regulation of system process | ABAT, ANPEP, ANXA6, AQP1, CAMK2G, CNN1, CRH, CRHBP, CYBA, DAPK3, DRD3, EMP2, CTTN, FLT1, GALR1, GDF9, GHSR, GTF2I, IGF1, INHA, KCNA1, KISS1, KNG1, PPP1R12B, PRKG1, RPS6KB1, SGK1, SLC22A5, SRF, TACR2, TNNC2, TNNC1, TNNI2, TRPC3, COL14A1, NR1H2, TRPV1, AKAP1, PHOX2B, CTDP1, KLF4, SLC9A3R1, AKAP6 |
1002 | GO:0050863 | 0.00 | 2.70 | 12.19 | 22 | 42 | regulation of T cell activation | ADAM8, BAD, CD3D, CD3G, CD5, DPP4, EFNB2, EGR3, FLOT2, FYN, GRB2, PDPK1, RAC1, RAG1, CCL21, TRAF2, VAV1, TNFSF14, IL1RL2, VNN1, GRAP2, SOX13 |
1003 | GO:0007507 | 0.00 | 2.70 | 27.77 | 50 | 96 | heart development | ACACB, ACVR2B, ADRA1B, ADRBK1, AP2B1, APLNR, PRDM1, CASP8, CRKL, VCAN, DNM2, EDNRA, EP300, EPOR, FBN1, GPC3, GNAQ, HHEX, ID1, ITGA4, KCNJ8, SMAD6, NTRK3, OXCT1, OXTR, PAM, PAX3, PCNA, PCSK5, PSKH1, PTN, PTPRJ, RAF1, RPS6KA2, SALL1, SCN5A, SHC1, SNAI1, SPARC, TRPS1, VEGFB, KCNAB1, DNAH11, ADAM19, CDKL1, NRP1, TRIP11, IFT140, SNX17, RB1CC1 |
1004 | GO:0045089 | 0.00 | 2.70 | 53.26 | 95 | 182 | positive regulation of innate immune response | ADAM8, BIRC3, XIAP, BTK, CALM3, CASP8, CD14, CD86, CD36, CHUK, CREB1, CTSK, CTSS, CYBA, COCH, DMBT1, DUSP7, ELK1, EP300, FYN, UBE2K, HPX, ICAM2, IFI16, IL12B, IRAK1, IRAK2, IRF1, ITGAM, ITPR1, ITPR3, JUN, LTF, PDPK1, PPP2R5D, PRKACB, PRKACG, PRKCE, MAPK1, MAPK3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PVR, RAF1, RPS6KA1, RPS6KA2, RPS6KA3, RPS19, RPS27A, SEC14L1, SKP1, STAT5B, SYK, HSP90B1, TYRO3, UBB, UBE2D1, UBE2D2, UBE2V1, VAV1, CUL1, IKBKG, RIPK1, RIPK2, PGLYRP1, UBA3, RPS6KA5, PSMF1, NR1D1, PUM1, TRIL, NR1H4, TANK, PSME3, PSMD14 |
1005 | GO:0002708 | 0.00 | 2.70 | 11.12 | 20 | 38 | positive regulation of lymphocyte mediated immunity | C3, CD28, CD40, FCER1A, FCER2, HPX, IFNG, IL12B, P2RX7, PVR, XCL1, STAT5B, STAT6, TRAF2, TNFSF4, UNG, VAV1, ZP3, FZD5, TNFSF13 |
1006 | GO:0042551 | 0.03 | 2.70 | 5.55 | 10 | 19 | neuron maturation | ABL2, APP, CLN5, EPHA8, GNAQ, NRCAM, RB1, CNTN2, PICK1, IRX5 |
1007 | GO:0007272 | 0.00 | 2.70 | 17.27 | 31 | 59 | ensheathment of neurons | CD9, CLU, LPAR1, EGR2, FGFR3, GPC1, HEXB, HGF, NRG1, IFNG, ILK, KCNJ10, MAL, CLDN11, PTEN, RARA, RARB, RXRA, SCN2A, SCN8A, SLC8A3, CNTN2, TSC1, UGT8, ZNF24, ATRN, CNTNAP1, EIF2B2, EIF2AK3, RNF10, OLIG2 |
1008 | GO:0006607 | 0.03 | 2.69 | 5.56 | 10 | 19 | NLS-bearing protein import into nucleus | RERE, CBLB, FYB, KPNA1, KPNA2, KPNA3, KPNA4, IPO5, RANBP2, TRPS1 |
1009 | GO:0006929 | 0.03 | 2.69 | 5.56 | 10 | 19 | substrate-dependent cell migration | ABL2, ADAM8, CTTN, EPHA8, FBLN1, ITGA2, OPHN1, NRP1, ITGB1BP1, SLIT2 |
1010 | GO:0008209 | 0.03 | 2.69 | 5.56 | 10 | 19 | androgen metabolic process | SCARB1, AKR1C4, CYP3A4, HSD17B3, HSD17B4, SRD5A1, UGT2B7, AKR1C3, SGPL1, DHRS9 |
1011 | GO:0014743 | 0.03 | 2.69 | 5.56 | 10 | 19 | regulation of muscle hypertrophy | CAV3, IGF1, P2RX4, SLC9A1, TRPC3, COL14A1, AKAP1, PDE5A, CTDP1, AKAP6 |
1012 | GO:0032722 | 0.03 | 2.69 | 5.56 | 10 | 19 | positive regulation of chemokine production | ALOX15B, CD74, CSF1R, DDX3X, FFAR3, IFNG, P2RY2, ADAM17, RIPK2, IL1RL1 |
1013 | GO:0033598 | 0.03 | 2.69 | 5.56 | 10 | 19 | mammary gland epithelial cell proliferation | BAX, BRCA2, CHUK, EPHA2, ETV4, GATA3, GPX1, ID2, MAPK1, STAT6 |
1014 | GO:0045661 | 0.03 | 2.69 | 5.56 | 10 | 19 | regulation of myoblast differentiation | BMP4, FLOT2, FLT3LG, IGFBP3, IL18, ILK, SOX9, NR2C2, TNFSF14, CXCL14 |
1015 | GO:0060997 | 0.03 | 2.69 | 5.56 | 10 | 19 | dendritic spine morphogenesis | CDK5, CTNND2, EFNA1, EPHA4, EPHB1, EPHB2, EPHB3, CAPRIN1, PTEN, LRP8 |
1016 | GO:0098751 | 0.03 | 2.69 | 5.56 | 10 | 19 | bone cell development | ATP6AP1, EP300, KIT, LTF, PIP4K2A, PTPN6, SRF, TAL1, TYROBP, WASF2 |
1017 | GO:0007417 | 0.00 | 2.69 | 14.29 | 26 | 51 | central nervous system development | ACVR1B, ALDH3A2, TPP1, COL2A1, COX7B, VCAN, ATN1, RCAN1, EPHB1, GABRA4, JARID2, MAL, NRCAM, PAM, PCP4, SERPINI1, PSPN, PTK2, RPS6KA3, SEMA3F, SPOCK1, UGT8, RNF103, JRKL, VNN2, VNN1 |
1018 | GO:0021537 | 0.00 | 2.69 | 32.44 | 58 | 111 | telencephalon development | ALDH1A3, ANXA3, AQP1, ASCL1, AVPR2, BAD, BAX, BBS4, BMP4, CDK6, CSF1R, CX3CR1, DBI, EMX1, EMX2, EPHA5, EZH1, FGF8, KAT2A, NRG1, HPRT1, ID2, KCNA1, NTRK2, OGDH, OXTR, PEX13, PROX1, PTEN, PTPRZ1, RAC1, RARA, RARB, RFX4, SALL1, SCN5A, TRA2B, SIX3, SLC8A1, SLC8A3, SRD5A1, SRF, TACC1, CNTN2, NR2F1, NR2E1, TNR, TP73, TSC1, LRP8, IFT88, USP9X, EOMES, SEMA7A, NUMB, NRP1, SLIT2, ZEB2 |
1019 | GO:0009725 | 0.01 | 2.68 | 7.62 | 14 | 28 | response to hormone | ACAT1, AK2, ANG, CBLB, PTK2B, H3F3B, HCLS1, HPN, ICAM1, ITGB1, OXCT1, SORD, SRF, UQCRFS1 |
1020 | GO:0001655 | 0.00 | 2.68 | 43.73 | 78 | 150 | urogenital system development | ACAT1, ACTA2, ACVR2B, AGTR1, AGTR2, ANGPT1, ANGPT2, AQP1, ARG2, ASS1, BAX, CAT, CENPF, COL4A3, CTSH, DCN, ACE, EDNRA, EFNB2, EMX2, ENPEP, EPHA4, EPHB2, EPHB3, FBN1, FGF8, FOXD1, GATA3, GDNF, GPC3, HAS2, HMGCS2, HOXC11, ID2, ILK, ITGA6, KCNJ1, KCNJ8, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, ODC1, OVOL1, PAX2, PCSK5, PRKX, PSPN, PROX1, PTCH1, RARB, RET, SALL1, SDC1, SDC4, SLC12A1, SLC34A1, SOX4, SOX11, SRD5A1, TP73, TSC1, UPK3A, VEGFA, WFS1, WNT1, WNT11, IFT88, SERPINB7, IQGAP1, NRP1, SGPL1, RGN, SLIT2, IFT140, BCL2L11, SPRY1 |
1021 | GO:0016032 | 0.00 | 2.68 | 61.60 | 110 | 215 | viral process | AP2B1, BIN1, SLC25A4, TRIM23, ARF1, BAX, BICD1, BNIP3L, BUB1, CAMLG, CASP8, CCNT2, CDC25C, CENPA, AP2M1, AP1S1, AP2S1, CCR3, COPB1, CREB1, CX3CR1, DDX11, DMBT1, E4F1, EPHA2, EIF4A1, EIF4A2, EIF4E, FCGR2B, FDPS, FYN, KAT2A, GRB2, HMGA1, HPX, SP110, IL2RB, IL2RG, KDR, IPO5, MFGE8, MAPK1, MAPK3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RAB6A, RAC1, RALA, RANBP1, RB1, SATB1, SET, SHC1, SKP1, STAT2, STAT3, SYK, TAF4B, TAF10, TBP, TSPAN7, TNFRSF1A, TOP1, TP73, UBE3A, SUMO1, UNG, VDAC1, VIM, EIF4H, XRCC5, CUL4A, CUL2, CUL1, IKBKG, DYNLL1, EIF4G3, AP1M1, CLDN6, PSMF1, KDM4A, VPRBP, CUL7, RBX1, AP1M2, RAD50, ABI2, WASF2, PSME3, PSMD14 |
1022 | GO:0007093 | 0.00 | 2.68 | 13.36 | 24 | 46 | mitotic cell cycle checkpoint | BCL2L1, BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DUSP1, MAD2L1, PRCC, RB1, RPL24, TTK, UBE2D1, ZNF207, SMC1A, CDC23, CDC16, ZW10, BUB3, MAD2L1BP, KNTC1 |
1023 | GO:0022904 | 0.00 | 2.68 | 18.44 | 33 | 63 | respiratory electron transport chain | ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, COX6A1, COX6B1, COX7B, COX7C, COX8A, COX15, CYC1, DLD, ETFA, ETFDH, SDHA, SDHB, SDHC, SDHD, SNCA, TAZ, UCP1, UQCRC1, UQCRC2, UQCRFS1, UQCRH, SLC25A12, SLC25A14, COX5A, SLC25A13 |
1024 | GO:0003073 | 0.02 | 2.68 | 6.12 | 11 | 21 | regulation of systemic arterial blood pressure | ANPEP, AVPR1B, AVPR2, CTSG, ACE, DRD3, DRD5, ENPEP, OXTR, SLC2A5, ATP6AP2 |
1025 | GO:0040011 | 0.00 | 2.68 | 162.21 | 284 | 577 | locomotion | ACTB, AP2B1, AGTR1, ANG, APBB2, APP, ARAF, ARF4, ASCL1, ASTN1, RERE, ATP1A2, ATP2B2, BAX, DST, BSG, TSPO, CACNB1, CACNB2, CACNB4, CALM3, CAMK2A, CAMK2G, CD44, CD58, CD72, CD151, CHN1, AP2M1, AP2S1, CCR3, CCR8, COL2A1, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF2, CSF2RB, CSNK2A1, CSNK2A2, VCAN, CSPG4, CTGF, DBH, DCC, DLG3, DLX5, DNM1, DNAH8, DUSP5, DUSP7, DUSP9, TYMP, EDNRB, EFNA3, EFNA4, EFNA5, EFNB1, CELSR2, EGR2, EGR3, CTTN, EMX2, ENPEP, EPHA3, EPHA4, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, ERG, ETV1, ETV4, F2, FAP, FGF3, FGF6, FGF8, FGF9, FGFR3, FPR1, FPR2, FPR3, FUT8, FYN, GAS8, GDNF, GFRA1, B4GALT1, GPC1, GPM6A, XCR1, GPR15, GPX1, GRB2, GRIN2A, HIST1H1T, HEXB, NR4A1, HRH1, ID1, IL2RA, IL2RB, IL2RG, IL3, IL10, IL12B, ING2, ITGA6, ISL1, ITGA1, ITGA7, ITGA9, ITGAL, ITGAM, JUP, KIF5A, KRT2, LDHC, LIMK1, LSP1, MARK3, SMCP, NRCAM, NTRK2, NTN3, OGDH, OLR1, OPHN1, OTX2, PAX3, PCM1, PDE4B, PEX7, PEX13, PGK2, PIK3C2A, PIK3C2B, PPP5C, PRKCI, PRKCQ, PRKG1, MAPK3, PSPN, PROC, PROS1, PSG2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTPN6, PTPRA, RAB1A, RALA, RASA2, RFX3, RNASE2, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS19, RPS27A, RYK, S100A2, S100A8, S100A9, S100A12, S100P, SAA4, SCN5A, SCNN1B, CCL22, SDC1, SELL, SFTPD, ITSN1, SHC1, SIAH2, SIX3, SLC9A1, FSCN1, SORD, SOS2, SOX10, SPOCK1, SPTA1, SPTB, STAT5B, XCL2, SYK, T, CNTN2, NR2F1, TNR, TNS1, TOP2B, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TYK2, TYROBP, UBB, CLRN1, VAV1, LRP8, FZD3, ARHGEF5, FOSL1, FGF23, SLC7A5, USP9X, USP9Y, FZD4, CUL3, SORBS2, CNTNAP1, KLF7, PEA15, DNAH11, TNFSF12, CD84, AKAP4, SGPL1, PHOX2B, RPS6KA4, DOK2, PSTPIP1, DCLK1, RPS6KA5, KL, NRXN3, NRXN1, PSMF1, NRG2, CDC42BPB, FEZ2, SDC3, ARHGEF11, ZEB2, GAB2, KIAA0319, RBX1, RANBP9, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, AKAP9, ABI2, RASA4, WASF2, PSME3, PSMD14, RCAN2 |
1026 | GO:0019722 | 0.00 | 2.68 | 12.83 | 23 | 44 | calcium-mediated signaling | AGTR1, ATP1A2, BTK, CASQ1, CASQ2, CMKLR1, RCAN1, PTK2B, HRC, ITPR1, KDR, NTRK2, P2RY11, PDPK1, PLN, RYR2, SELE, SELP, SLC8A1, LAT2, RGN, EIF2AK3, RCAN2 |
1027 | GO:0048708 | 0.02 | 2.67 | 6.13 | 11 | 21 | astrocyte differentiation | BIN1, CDK6, EPHA4, HMBS, ID2, S100A8, S100A9, SOX9, STAT3, TAL1, CNTN2 |
1028 | GO:1901700 | 0.00 | 2.67 | 26.71 | 49 | 100 | response to oxygen-containing compound | ACVR2B, ADCYAP1R1, AHR, ANGPT2, STS, ATP5G3, AVPR1B, AVPR2, BRCA2, DAGLA, CD4, CD9, CHAT, COL6A2, CYC1, DBH, EGR2, EIF2B1, ENSA, GATA3, GOT2, GYS2, HADHA, HLCS, IHH, INPPL1, IRF5, LTA4H, PAM, PCK1, PTH, QDPR, RBBP4, RBBP8, SORT1, SLC2A2, SLC34A1, STXBP3, NR2F2, TRPM2, PRDM2, SLC14A2, NR0B2, EIF2B3, EIF2B2, MBD4, GPR55, RNF40, EPM2AIP1 |
1029 | GO:0006775 | 0.00 | 2.67 | 12.29 | 22 | 42 | fat-soluble vitamin metabolic process | CBR1, AKR1C4, CLPS, CYP3A4, CYP27B1, GPC4, GPC5, GPC3, GPC1, IFNG, RBP1, RBP2, RLBP1, SDC1, SDC4, SNAI1, VDR, LRP8, FGF23, CYP4F2, AKR1C3, SDC3 |
1030 | GO:0072507 | 0.00 | 2.67 | 63.80 | 113 | 218 | divalent inorganic cation homeostasis | ABL1, ABL2, ADCYAP1R1, ADRA1B, AGTR1, ANXA6, APP, ATP1A2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, AVPR1B, BAX, BDKRB1, BMP4, CACNA1A, CACNB4, CALM3, CASQ1, CASQ2, CAV3, CD4, CD36, CD40, CD52, CCR1, CCR3, CCR8, CYBA, CYP27B1, CD55, DIAPH1, DRD3, DRD5, S1PR1, LPAR1, EDNRA, EDNRB, EPOR, F2, F2R, PTK2B, GALR1, GNA15, GNAT2, GNG3, XCR1, GRINA, GRM1, GTF2I, HEXB, HRC, HTR2C, IL13, ITGB1, ITPR1, ITPR3, KCNA1, KCNA5, KCNK3, KDR, KISS1, KNG1, NTSR1, OXTR, P2RX3, P2RX4, P2RX5, P2RX7, P2RY2, P2RY4, PDPK1, PLN, PRKCB, PRKCE, PRKD1, PTH, PTPN6, PYGM, RYR1, RYR2, S100A8, S100A9, CCL21, XCL1, SLC8A1, SLC8A3, SNCA, STC1, TNNI3, TPT1, HSP90B1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, VDR, TRPV1, WFS1, SLC30A1, SLC30A2, S1PR4, INPP4B, AP3D1, RGN, VAPB, KL, GSTO1, AKAP6, ATG5, ATP2C2 |
1031 | GO:0045785 | 0.00 | 2.67 | 39.26 | 70 | 135 | positive regulation of cell adhesion | ADA, ADAM8, ANGPT1, ANXA1, BAD, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD28, CD86, CD44, CD59, CD63, CD74, CTLA4, CD55, DHPS, DPP4, EFNB1, EFNB2, EGR3, FLOT2, FYN, GATA3, GRB2, NRG1, FOXA2, IFNG, IGF1, IGF2, IHH, IL2RA, IL12B, IL18, ITGA6, ITGA2, ITGA4, ITGAL, ITGAV, SMAD7, PDPK1, PRKCQ, PTAFR, RAG1, RAP1GAP, RARA, XCL1, CX3CL1, SELP, SPTA1, STAT5B, TRAF2, TNFSF4, VAV1, ZP3, AP3B1, CHRD, TNFSF14, TNFSF9, RIPK2, TNFRSF18, IL1RL2, VNN1, AP3D1, TNFSF18, GRAP2, BAG4 |
1032 | GO:0051402 | 0.02 | 2.67 | 6.69 | 12 | 23 | neuron apoptotic process | APAF1, APP, BOK, ATN1, GAPDH, GATA3, GPX1, GRID2, RB1, SCN2A, TP63, AATK |
1033 | GO:0043491 | 0.02 | 2.67 | 6.69 | 12 | 23 | protein kinase B signaling | CAV3, CD40, NTRK2, PAX2, PIK3C2B, RPS6KB1, RPS6KB2, RRAS, SOX9, TYRO3, INPP4B, RNF41 |
1034 | GO:0009612 | 0.00 | 2.67 | 15.06 | 27 | 52 | response to mechanical stimulus | ANGPT2, ASNS, BDKRB1, BGLAP, CCNB1, ENTPD2, CLCN6, DCN, ETS1, ETV1, F3, PTK2B, GATA4, JUNB, JUND, KCNA5, KCNK2, NTRK2, P2RX3, P2RX7, PSPH, PTCH1, RPS6KB1, XPA, FOSL1, NRXN1, NRXN2 |
1035 | GO:0007131 | 0.02 | 2.67 | 6.15 | 11 | 21 | reciprocal meiotic recombination | ERCC4, RAD21, RAD51, RAD51C, RAD51B, RAD51D, TOP2A, TOP2B, XRCC2, REC8, RAD50 |
1036 | GO:0007620 | 0.02 | 2.67 | 6.15 | 11 | 21 | copulation | ABAT, ADA, CNR1, EDNRA, EDNRB, OXTR, P2RX1, P2RY2, SLC6A4, VIP, DDO |
1037 | GO:0032881 | 0.02 | 2.67 | 6.15 | 11 | 21 | regulation of polysaccharide metabolic process | ADRA1B, CLTC, GCGR, HAS2, IGF1, IGF2, INS, PPP1CA, PTH, DYRK2, EPM2AIP1 |
1038 | GO:0033572 | 0.02 | 2.67 | 6.15 | 11 | 21 | transferrin transport | ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, CLTC, DNM2, ATP6V0E1, ATP6V0D1, RAB11B, ATP6V1G1 |
1039 | GO:0035272 | 0.02 | 2.67 | 6.15 | 11 | 21 | exocrine system development | CLCN2, EDA, FGF7, FGF8, HGF, IGF1, IGF1R, IGF2, SOX9, SOX10, NRP1 |
1040 | GO:0051966 | 0.02 | 2.67 | 6.15 | 11 | 21 | regulation of synaptic transmission, glutamatergic | ATP1A2, CNR1, PTK2B, NTRK2, OPHN1, OXTR, PTGS2, SYT1, TNR, DGKI, NRXN1 |
1041 | GO:0090199 | 0.02 | 2.67 | 6.15 | 11 | 21 | regulation of release of cytochrome c from mitochondria | BAD, BAX, BCL2L1, BIK, GPX1, HGF, IGF1, OPA1, HRK, TNFSF10, BCL2L11 |
1042 | GO:0030104 | 0.00 | 2.66 | 12.88 | 23 | 44 | water homeostasis | ADCY1, ADCY7, AQP1, AVPR2, GHRHR, GNAS, HAS2, IGF1, KRT16, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, SCNN1A, SCNN1B, SCNN1G, SRF, WFS1, CYP4F2, TP63, CLDN1 |
1043 | GO:0042110 | 0.00 | 2.66 | 16.74 | 30 | 58 | T cell activation | ABL1, ABL2, BAX, BMX, ZFP36L2, CASP8, RUNX2, CD7, CD8A, TNFSF8, CD151, CDK6, FLT3, INS, ITGAD, KIT, SMAD3, P2RX7, RAG2, RPL22, SATB1, SOX4, SP3, SRF, ADAM17, WAS, WNT1, FZD5, FZD7, FZD8 |
1044 | GO:0002262 | 0.00 | 2.66 | 20.19 | 36 | 69 | myeloid cell homeostasis | ACVR1B, ADAR, ADD1, ALAS2, ANXA1, ARNT, AXL, BAX, BMP4, CDK6, CEBPG, ETS1, ETV2, GATA3, HCLS1, PRMT1, ID2, IFNG, INHA, KIT, KITLG, PRDX1, PDE4B, PTPN2, RB1, RHAG, RPS19, SP1, SP3, SRF, STAT5B, ADAM17, TAL1, VEGFA, ZNF16, BCL2L11 |
1045 | GO:0061564 | 0.00 | 2.66 | 121.30 | 212 | 416 | axon development | ABL1, ABL2, ACTB, ADAM10, ADCY1, AP2B1, ANGPT1, APBB1, APBB2, APP, ARAF, ARHGAP4, BMPR2, CACNA1A, CACNB1, CACNB2, CACNB4, CALM3, CAMK2A, CAMK2G, CD72, CDK5, CHN1, CHRNB2, AP2M1, AP2S1, CNP, COL2A1, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2, CSF2RB, CSNK2A1, CSNK2A2, DCC, DLG3, DLX5, DNM1, DNM2, DPYSL3, EPYC, DUSP5, DUSP7, DUSP9, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EFNB2, EGR2, EPHA2, CTTN, EPHA5, EPHA8, EPHB1, ETV1, ETV4, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FYN, GATA3, GDI1, GDNF, GFRA1, GOLGA4, GPC1, GRB2, GRIN2A, NRG1, IL2RA, IL2RB, IL2RG, IL3, ILK, ITGA1, ITGA2, ITGA5, ITGA9, ITGAV, ITGB1, KIF5A, KIT, LIMK1, MAP1B, MARK3, RAB8A, KITLG, NTRK2, NTN3, OPHN1, OTX2, PAX2, PPP5C, PRKCQ, MAPK1, MAPK3, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTK2, PTPRA, RAB3A, RAC1, RAC2, RAF1, RASA2, RET, RNF6, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RRAS, RYK, SCN5A, SEMA3F, ITSN1, SHC1, SIAH2, SOS2, SPTA1, SPTB, SRF, TBCE, NR2E1, TOP2B, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, VCL, VEGFA, SEMA3B, FZD3, FGF23, RND2, USP9X, PICALM, CUL3, SEMA7A, CNTNAP1, KLF7, UNC5C, NUMB, PEA15, NRP2, ARHGEF7, PHOX2B, RPS6KA4, ARHGEF1, DCLK1, RPS6KA5, SLIT2, KL, NRXN3, NRXN1, PSMF1, NRG2, AATK, FEZ2, RAPGEF2, SEMA3E, ARHGEF11, RBX1, RANBP9, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, AKAP9, RASA4, PSME3, PSMD14 |
1046 | GO:0035051 | 0.00 | 2.65 | 14.01 | 25 | 48 | cardiocyte differentiation | AGTR2, BMP4, CAV3, CCNB1, CXADR, EFNB2, KAT2A, ITGB1, MAPK1, MAPK3, PROX1, RARA, RARB, RXRA, SGCB, SLC8A1, SLC9A1, TSC1, COL14A1, IFT88, ARID1A, SORBS2, CTDP1, AKAP6, ATG5 |
1047 | GO:0031670 | 0.02 | 2.65 | 6.72 | 12 | 23 | cellular response to nutrient | ATP2B1, BGLAP, CCNE1, COL1A1, CYP27B1, ITGB1, PENK, PIM1, PTN, VDR, FGF23, NR1H4 |
1048 | GO:0001659 | 0.02 | 2.64 | 6.73 | 12 | 23 | temperature homeostasis | ABAT, CNR1, DBH, EDNRB, GPX1, IL1A, IL1RN, NTSR1, PTGS2, STAT3, TRPV1, NR1D1 |
1049 | GO:0021695 | 0.02 | 2.64 | 6.73 | 12 | 23 | cerebellar cortex development | AGTR2, ARCN1, RERE, ATP2B2, CACNA1A, CDK5, GRID2, OGDH, PROX1, RFX4, USP9X, NRXN1 |
1050 | GO:0031103 | 0.02 | 2.64 | 6.73 | 12 | 23 | axon regeneration | TSPO, CTNNA1, DHFR, EPHA4, ISL1, JUN, NTRK3, PTEN, RXRA, TNR, KLF4, CHST3 |
1051 | GO:0035176 | 0.02 | 2.64 | 6.73 | 12 | 23 | social behavior | BBS4, CHRNB2, DRD3, EIF4EBP2, GRID1, OXTR, PTEN, SLC6A4, NR2E1, NRXN3, NRXN1, NRXN2 |
1052 | GO:0042088 | 0.02 | 2.64 | 6.73 | 12 | 23 | T-helper 1 type immune response | ANXA1, BCL3, IL12B, IL18, XCL1, STAT6, TNFSF4, RIPK2, IL18R1, IL1RL1, IL27RA, IL18BP |
1053 | GO:0048265 | 0.02 | 2.64 | 6.73 | 12 | 23 | response to pain | TSPO, CACNA1A, CACNA1B, COMT, CRH, DBH, EDNRB, GJA4, P2RX3, RET, SLC6A2, TRPV1 |
1054 | GO:2000107 | 0.02 | 2.64 | 6.73 | 12 | 23 | negative regulation of leukocyte apoptotic process | ADA, AXL, BMP4, CD74, TSC22D3, HCLS1, IDO1, KITLG, PRKCQ, RAG1, CCL21, AURKB |
1055 | GO:2000179 | 0.02 | 2.64 | 6.73 | 12 | 23 | positive regulation of neural precursor cell proliferation | ASCL1, CX3CR1, DCT, IGF1, PROX1, RSU1, CX3CL1, SMARCD3, SOX10, NR2E1, VEGFA, FZD3 |
1056 | GO:0043066 | 0.00 | 2.64 | 82.20 | 145 | 286 | negative regulation of apoptotic process | ADAR, ALB, ANXA1, ANXA4, ANXA5, APBB2, ARAF, ARF4, ASCL1, ASNS, BARD1, BCL2A1, BCL3, BLK, BNIP3L, CAT, CBL, CD59, CDKN1A, CLU, COL2A1, COMP, CSF1R, CSF2, CTH, CTNNA1, CTSH, CX3CR1, DAD1, DDB1, DFFA, DUSP1, EDNRA, EDNRB, EGR3, CTTN, FGF4, FLT4, GATA6, GCG, GLO1, GRINA, HPN, HSPA9, HSPB1, ID1, IFIT3, IGF1R, IHH, IL1A, IL2RB, IL10, ING2, INS, IRAK1, ITGA6, ITGAV, KCNJ1, LTF, MAD2L1, SMAD3, SMAD6, YBX1, NTSR1, OPA1, PA2G4, PIM1, PRKAA1, DNAJC3, PROC, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, RARA, RARB, RPS3A, RPS6KB1, RPS27A, CX3CL1, SGK1, STIL, SLC9A1, SNAI1, SOX9, SOX10, STAT3, STAT5B, SUPV3L1, NR2E1, TPT1, HSP90B1, UBB, UNG, VDAC2, VIP, WNT1, WNT11, YWHAZ, ZNF16, FZD3, API5, MADD, TP63, PEA15, RIPK2, TNFRSF18, TNFRSF10D, VNN1, TAX1BP1, TNFSF18, SOCS3, RGN, ARHGEF2, EIF2AK3, ATG5, PSMF1, BAG5, BAG4, RB1CC1, AREL1, NR1H4, TRAP1, PSME3, DHRS2, PSMD14 |
1057 | GO:0045787 | 0.01 | 2.64 | 8.94 | 16 | 31 | positive regulation of cell cycle | ASCL1, CCNC, CCNT2, OVOL1, PIM1, RARA, SETMAR, STIL, SLC6A4, SRPK2, TRIM21, ADAM17, NR2E1, FOSL1, CCPG1, BCL2L11 |
1058 | GO:0050778 | 0.00 | 2.64 | 12.27 | 22 | 43 | positive regulation of immune response | ANXA1, CD40, CNR1, CTSG, FCER1A, FCER2, FFAR3, HRG, IFNG, IL13, P2RX7, PTAFR, STAT6, TRAF2, UNG, ZP3, FZD5, SEMA7A, VAMP8, TNFSF13, IL27RA, GAB2 |
1059 | GO:0023014 | 0.00 | 2.63 | 140.48 | 243 | 480 | signal transduction by protein phosphorylation | ABL1, ABL2, ACVR1B, ACVR2B, ACVRL1, ADAM8, ADRA1B, ALK, ANGPT1, ARAF, ATF3, ATP6AP1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, C3, CALM3, CAMK2A, CAMK2G, CAV3, CD36, CD40, CD44, CD74, CHUK, CCR1, CREB1, CRKL, CRYAB, CRYBA1, CSF1R, CSF2, CSF2RB, CSPG4, CTGF, CTSH, DUSP1, DUSP5, DUSP7, DUSP9, LPAR1, EDNRA, EFNA1, EPHA2, ELK1, EPHA4, EPHA8, EPHB1, EPOR, ERCC6, F2R, PTK2B, FBLN1, FCER1A, FGA, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FLT1, FLT3, FLT4, FPR1, FSHR, FYN, GCG, GDF9, GNG3, GRB2, RAPGEF1, GRIN2A, GRM1, HGF, NRG1, HMGCR, PRMT1, HTR2C, ICAM1, ID1, IGF1, IGF1R, IGF2, IGFBP3, IL1A, IL2RA, IL2RB, IL2RG, IL3, IL18, ILK, INHA, INS, IRAK1, IRAK2, ITGA1, ITGAV, ITGB1, JUN, KCNH2, KDR, KISS1, KIT, SMAD1, MARK3, MEN1, KITLG, MAP3K11, NTRK2, NTRK3, OXTR, P2RX7, PRDX1, PHB, PPP2R1A, PPP2R5D, PPP5C, PRKAA1, PRKCE, MAPK1, MAPK3, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, PTPN2, PTPN6, PTPRA, PTPRJ, PTPRR, RAF1, RAP1A, RAP2A, RASA2, RBM4, RET, RPS3, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RRAS, RYK, S100A7, S100A12, CCL21, CCL22, CCL25, XCL1, CX3CL1, SHC1, SKP1, SLAMF1, SMPD1, SORL1, SOX9, SPTA1, SPTB, STK10, STYX, XCL2, SYK, TNFRSF1B, TP73, TPD52L1, NR2C2, TRAF2, TSG101, TYRO3, UBB, VEGFA, VEGFB, FZD5, SCG2, ARHGEF5, FGF23, FZD4, FZD7, FZD8, CUL3, CUL1, SEMA7A, IKBKG, MADD, PDE5A, PEA15, RIPK1, RIPK2, NRP1, BMP15, RPS6KA5, ITGB1BP1, GPR55, KLF4, KL, SLC9A3R1, PSMF1, GDF15, NRG2, TRAF4, RAPGEF2, SLK, RASSF2, RB1CC1, ZEB2, OXSR1, RBX1, SH2D3C, SH2D3A, RANBP9, AKAP9, RASA4, ATP6AP2, RNF41, PSME3, PSMD14, SPRY1 |
1060 | GO:0048634 | 0.00 | 2.63 | 15.22 | 27 | 52 | regulation of muscle organ development | ARNTL, BMP4, CAV3, CCNB1, CENPF, CXADR, DDX5, TSC22D3, EFNB2, FGF3, FGF8, GATA4, GATA6, GPC1, NRG1, HMGCR, RBPJ, KCNK2, SMAD3, PRKAA1, RPS6KB1, TP73, COL14A1, USP2, CTDP1, AKAP6, NR1D2 |
1061 | GO:1901861 | 0.00 | 2.63 | 15.22 | 27 | 52 | regulation of muscle tissue development | ARNTL, BMP4, CAV3, CCNB1, CENPF, CXADR, DDX5, TSC22D3, EFNB2, FGF3, FGF8, GATA4, GATA6, GPC1, NRG1, HMGCR, RBPJ, KCNK2, SMAD3, PRKAA1, RPS6KB1, TP73, COL14A1, USP2, CTDP1, AKAP6, NR1D2 |
1062 | GO:0043330 | 0.01 | 2.63 | 7.32 | 13 | 25 | response to exogenous dsRNA | DDX1, IFIT1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, KCNJ8, MAPK1, MAPK3, RIPK2, DDX21 |
1063 | GO:0055117 | 0.01 | 2.62 | 7.88 | 14 | 27 | regulation of cardiac muscle contraction | ADRA1B, CALM3, CASQ2, CAV3, CTGF, HRC, KCNQ1, SMAD7, P2RX4, SLC8A1, SLC9A1, PDE5A, GSTO1, HCN4 |
1064 | GO:0060333 | 0.01 | 2.62 | 7.89 | 14 | 27 | interferon-gamma-mediated signaling pathway | CAMK2A, CAMK2G, CD44, ICAM1, IRF1, IRF5, CIITA, OAS1, OAS3, PTAFR, SP100, TRIM21, TRIM25, OASL |
1065 | GO:0002429 | 0.00 | 2.61 | 53.51 | 94 | 183 | immune response-activating cell surface receptor signaling pathway | ABL1, ACTB, ADA, BAX, BLK, BTK, CACNB4, CALM3, CASP8, CBLB, CD3D, CD3E, CD3G, CD4, CD28, CHUK, CTLA4, ELF1, EP300, FCGR2A, FGR, FYB, FYN, GATA3, GRB2, ICAM2, ITPR1, ITPR3, KCNN4, LIMK1, PDE4B, PDPK1, PRKACB, PRKACG, PRKCB, PRKCE, PRKCQ, MAPK1, MAPK3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, PTPN2, PTPN6, PTPRJ, RAC1, RAF1, RPS27A, SKP1, SYK, UBB, UBE2D1, UBE2D2, UBE2V1, VAV1, WAS, LAT2, CUL1, IKBKG, RIPK2, UBA3, RPS6KA5, GRAP2, PSMF1, BCAR1, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, WASF2, PSME3, PSMD14 |
1066 | GO:0031663 | 0.01 | 2.61 | 7.90 | 14 | 27 | lipopolysaccharide-mediated signaling pathway | PRDM1, CD6, CD14, SCARB1, CD55, IL18, IRAK1, IRAK2, LTF, PRKCE, MAPK1, MAPK3, PTAFR, RIPK2 |
1067 | GO:0034080 | 0.01 | 2.61 | 7.90 | 14 | 27 | CENP-A containing nucleosome assembly | CENPA, CENPI, RBBP4, HIST1H4I, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, RUVBL1 |
1068 | GO:0044419 | 0.00 | 2.61 | 112.72 | 196 | 389 | interspecies interaction between organisms | ADAR, AP2B1, BIN1, SLC25A4, AQP1, TRIM23, ARF1, BAX, BICD1, BNIP3L, BST2, BUB1, CAMLG, CASP8, CCNT2, CD28, CD36, CDC25C, CENPA, AP2M1, AP1S1, AP2S1, CCR3, COPB1, CREB1, CTSG, CX3CR1, DDB1, DDX3X, DDX5, DDX6, DDX11, DMBT1, E4F1, EPHA2, EIF4A1, EIF4A2, EIF4E, EP300, ERCC3, FAU, FCGR2B, FDPS, NR5A2, FYN, KAT2A, GPX1, GRB2, HMGA1, HPN, HPX, IFI16, SP110, IFNG, IL2RB, IL2RG, IL10, IL12B, ISG20, JUN, KDR, IPO5, MFGE8, OAS1, OAS3, OSBP, CHMP1A, PCSK5, PPIB, PPID, MAPK1, MAPK3, PROX1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RAB1A, RAB6A, RAC1, RALA, RAN, RANBP1, RB1, REST, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, SATB1, SET, SHC1, SKP1, SLPI, SMARCA4, SP1, SP100, SRPK2, SSRP1, STAT2, STAT3, STAU1, SYK, TAF4B, TAF10, TARBP2, TBP, TSPAN7, TNFRSF1A, TOP1, TOP2A, TP73, TSG101, UBB, UBE3A, SUMO1, UNG, USF1, VDAC1, VIM, EIF4H, XRCC5, CUL4A, CUL2, CUL1, IKBKG, OASL, DYNLL1, EIF4G3, AP1M1, PGLYRP1, RPL14, CLDN6, CTDP1, RPL23, RAB9A, ATG5, PSMF1, KDM4A, USP6NL, VPRBP, CUL7, RBX1, PDCD6IP, AP1M2, RAD50, ABI2, TRIM28, WASF2, ALYREF, PSME3, PSMD14 |
1069 | GO:0048667 | 0.00 | 2.61 | 119.98 | 208 | 412 | cell morphogenesis involved in neuron differentiation | ABL1, ACTB, ADAM10, ADCY1, AP2B1, ANGPT1, APBB1, APBB2, APP, ARAF, ARHGAP4, ATP2B2, BMPR2, CACNB1, CACNB2, CACNB4, CALM3, CAMK2A, CAMK2G, CD72, CHN1, AP2M1, AP2S1, CNP, COL2A1, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2, CSF2RB, CSNK2A1, CSNK2A2, DCC, DLG3, DLX5, DNM1, DNM2, DPYSL3, EPYC, DUSP5, DUSP7, DUSP9, EFNA3, EFNA4, EFNA5, EFNB1, EFNB2, EGR2, EPHA2, CTTN, EPHA3, EPHA5, EPHA8, ETV1, ETV4, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, GATA3, GDI1, GDNF, GFRA1, GOLGA4, GPC1, GRB2, GRIN2A, NRG1, IL2RA, IL2RB, IL2RG, IL3, ISL1, ITGA1, ITGA2, ITGA5, ITGA9, ITGAV, KIF5A, KIT, LIMK1, MAP1B, MARK3, RAB8A, KITLG, NRCAM, NTRK2, NTRK3, NTN3, OPHN1, OTX2, PAX2, PPP5C, PRKCQ, MAPK1, MAPK3, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTK2, PTPRA, RAB3A, RAC2, RAF1, RASA2, RB1, RET, RNF6, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RRAS, RYK, SCN5A, SEMA3F, ITSN1, SHC1, SIAH2, SOS2, SPTA1, SPTB, SRF, CNTN2, TBCE, TNR, TOP2B, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, CLRN1, VCL, VEGFA, SEMA3B, FZD3, FGF23, RND2, USP9X, CUL3, SEMA7A, CNTNAP1, UNC5C, NUMB, PEA15, NRP2, NRP1, ARHGEF7, PHOX2B, RPS6KA4, ARHGEF1, RPS6KA5, SLIT2, KL, SLC9A3R1, NRXN3, NRXN1, PSMF1, NRG2, AATK, FEZ2, SEMA3E, ARHGEF11, RBX1, RANBP9, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, AKAP9, RASA4, PSME3, PSMD14 |
1070 | GO:0045937 | 0.00 | 2.60 | 12.26 | 22 | 44 | positive regulation of phosphate metabolic process | ABCA1, ADCYAP1R1, AVPR2, DRD5, FZD2, GHRHR, GNAS, GUCA1A, GUCA2A, GUCA2B, HRH1, NTSR1, P2RY11, PTAFR, PTH, RCVRN, STAT3, VIP, VIPR2, WFS1, AKAP12, GUCA1C |
1071 | GO:1903522 | 0.00 | 2.60 | 35.18 | 62 | 121 | regulation of blood circulation | ADA, ATP1A3, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, CACNA1B, CACNB1, CACNB2, CACNB4, CACNG1, CALM3, CASQ1, CASQ2, CAV3, CPS1, CTGF, CXADR, GAA, GATA4, HRC, IFNG, ITPR1, ITPR3, JUP, KCND2, KCND3, KCNH2, KCNJ2, KCNJ11, KCNJ14, KCNK3, KCNQ1, SMAD7, P2RX4, P2RY2, PDE4B, FXYD3, RYR1, RYR2, S100A1, SCN2B, SCN4B, SCN5A, SLC8A1, SLC8A3, SLC9A1, SREBF1, STC1, TACR3, TNNI3, TRPC1, SUMO1, VIP, KCNK6, GSTO1, NUP155, HCN4, ABCC9, AKAP9, IRX5 |
1072 | GO:1902806 | 0.00 | 2.60 | 28.97 | 51 | 99 | regulation of cell cycle G1/S phase transition | ANXA1, CDC6, CDK2, CDKN1A, DDX3X, ID2, KCNA5, MEN1, PIM1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTPN6, RB1, RPA2, RPS27A, SMARCA4, SOX4, ADAM17, TP73, UBB, UBE2E2, CDC45, CUL4A, TP63, CRADD, PSMF1, CTDSP2, PSME3, PSMD14, CTDSPL |
1073 | GO:0070373 | 0.01 | 2.60 | 8.49 | 15 | 29 | negative regulation of ERK1 and ERK2 cascade | ABL1, ATF3, CRYBA1, DUSP1, FBLN1, RAPGEF1, IGF1, PHB, PTPN2, PTPRR, ITGB1BP1, KLF4, SLC9A3R1, RANBP9, SPRY1 |
1074 | GO:2000145 | 0.00 | 2.60 | 113.84 | 197 | 389 | regulation of cell motility | ABL1, ABL2, ACTN4, ACVR1B, ACVRL1, ADA, ADAM8, ADAM10, AGTR2, ALOX15B, ANGPT1, ANGPT2, ANXA1, ANXA3, ANXA5, APOH, AQP1, ARHGAP4, ARHGAP5, ARHGDIB, BBS4, BCR, BDKRB1, BMP4, BMPR2, BST2, KRIT1, SCARB1, CD63, CD74, CDK5, CDK6, CCR1, CMKLR1, COL1A1, CSF1R, CTNNA1, CTSH, CX3CR1, DAPK3, DCN, ACE, DIAPH1, DPEP1, DPYSL3, ECM1, S1PR1, LPAR1, EDNRA, EFNA1, EPHA2, EMP2, ETS1, F2R, F3, F7, F10, PTK2B, FBLN1, EFEMP1, FGF4, FGF7, FGR, FLT1, FLT4, FSHB, GATA3, GPLD1, GRB7, CXCL2, CXCL3, HAS1, HAS2, HGF, NRG1, ONECUT1, HRG, HSPB1, ICAM1, IFNG, IGF1, IGF1R, IGFBP3, ILK, INS, ITGA2, ITGA4, ITGA5, ITGAV, ITGB1, JUN, KDR, KIT, KRT16, LAMA3, LAMA4, SMAD3, SMAD7, KITLG, NTRK3, DDR2, P2RY2, P2RY6, SERPINE1, PDPK1, SERPINF1, PF4V1, PFN2, PRCP, PRKCE, PRKD1, MAPK1, PRKX, PROX1, PTAFR, PTEN, PTGS2, PTK2, PTN, PTPRJ, PTPRR, PTPRZ1, RAC1, RAC2, RAF1, RAP2A, RAP2B, RET, RPS6KB1, RRAS, S100A7, CCL21, CCL25, CXCL6, CXCL5, XCL1, CX3CL1, SDC4, SELE, SELP, SEMA3F, SGK1, SLC8A1, SNAI1, SORL1, SOX9, SP100, SPARC, SRF, STAT3, STC1, STK10, ADAM17, NR2F2, NR2E1, TRIP6, VCL, VEGFA, VEGFB, VIL1, VTN, WAS, WNT11, ZP3, PTP4A1, SEMA3B, MADCAM1, SOX14, SEMA7A, IKBKAP, UNC5C, CHRD, NUMB, TNFSF14, ADAM15, TNFRSF18, NRP2, NRP1, ARHGEF7, TNFSF18, RGN, ITGB1BP1, KLF4, SLIT2, SLC9A3R1, ONECUT2, BAG4, CXCL14, BCAR1, PPM1F, RAPGEF2, SEMA3E, SLK, HDAC6, PDCD6, PTPRU, RNF41 |
1075 | GO:0071103 | 0.00 | 2.60 | 10.17 | 18 | 35 | DNA conformation change | ANXA1, CHD2, CHD4, DDX1, DDX3X, DDX11, HHEX, PURA, RAD51, SUPV3L1, WRN, XRCC5, CDC45, RECQL5, CHD1L, GINS1, RAD50, G3BP1 |
1076 | GO:0007603 | 0.00 | 2.60 | 18.14 | 32 | 62 | phototransduction, visible light | ABCA4, OPN1SW, CALM3, AKR1C4, CHRM1, CLPS, CNGA1, GPC4, GPC5, FNTA, OPN1MW, GPC3, GNAQ, GNAT1, GNGT1, GPC1, GUCA1A, GUCY2F, GUCY2D, PRKCQ, RBP1, RBP2, OPN1LW, RCVRN, RLBP1, SDC1, SDC4, LRP8, AKR1C3, RGS9, GUCA1C, SDC3 |
1077 | GO:0050867 | 0.00 | 2.60 | 43.31 | 76 | 148 | positive regulation of cell activation | ADA, ADAM8, ANXA1, AXL, BAD, PRDM1, BTK, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD28, CD86, CD40, CD59, CD74, CDKN1A, CHRNB2, CTGF, CTLA4, CD55, DHPS, DPP4, EFNB1, EFNB2, EGR3, FCER1A, FGR, FLOT2, FLT3LG, FYN, GATA3, GRB2, IFNG, IGF1, IGF2, IHH, IL2RA, IL12B, IL13, IL18, ITGAL, PDPK1, PRKCQ, PTAFR, PTPN6, RAC1, RAG1, RARA, RPS6KA1, CCL21, XCL1, SELP, SPTA1, STAT5B, STAT6, SYK, TRAF2, TNFSF4, UNG, VAV1, ZP3, AP3B1, VAMP8, TNFSF14, TNFSF13, TNFSF9, RIPK2, IL1RL2, VNN1, AP3D1, IL1RL1, GRAP2, GAB2 |
1078 | GO:0007498 | 0.00 | 2.59 | 18.73 | 33 | 64 | mesoderm development | ACVR2B, BMP4, BMPR1A, BMPR2, BMX, BTK, EPHA2, ETS2, ETV2, EXT2, EYA2, FGF8, ITGA2, ITGB1, SMAD1, SMAD3, OVOL1, PAX2, PRKAR1A, RPL38, SNAI1, SRF, T, TAL1, TSPY1, KDM6A, VEGFA, WNT11, EOMES, TP63, CHRD, KLF4, HAND1 |
1079 | GO:0021885 | 0.01 | 2.59 | 9.07 | 16 | 31 | forebrain cell migration | AXL, CDK5, CX3CR1, EMX2, NRG1, OGDH, PEX13, RAC1, SRF, CNTN2, NR2E1, TNR, TYRO3, LRP8, NRP1, SLIT2 |
1080 | GO:0010942 | 0.00 | 2.59 | 89.25 | 155 | 306 | positive regulation of cell death | ADAM8, AES, AGTR2, ALDH1A3, BIN1, ANXA1, ANXA5, APAF1, APBB1, APBB2, ARHGAP4, ATF3, BARD1, BCL2A1, BCL2L1, BIK, BMP4, BNIP3L, BOK, BUB1, TSPO, CAMK2A, CASP8, CD14, TNFRSF8, CD40, CDK4, CDKN1A, CNR1, COL4A3, CREB1, CRH, CRYBA1, CTGF, CTLA4, CTNNA1, CTSH, DAPK3, DDX3X, DFFA, DHODH, DNM2, DNMT3A, DUSP1, LPAR1, ERCC3, F2R, F3, FAP, FGD1, B4GALT1, GPLD1, GRIN2A, HBA1, HBA2, HIP1, HMGCR, HP, HRG, IFNG, IGF2R, IGFBP3, IL10, IL12B, IDO1, ING2, ITGA6, IRF5, ITGB1, KCNK2, KNG1, SMAD3, MAL, NTRK3, NTSR1, P2RX1, P2RX7, PPID, PPP1CA, PPP2R1A, PPP2R1B, PRKCI, PTEN, PTGIS, PTGS2, PTN, PTPN2, RAC1, RARB, REST, RET, RPS3, RPS6, RPS6KA2, RPS27A, RXRA, SORT1, S100A8, S100A9, SFPQ, ITSN1, SLC9A1, SMPD1, SIGLEC1, SNCA, SOS2, SOX4, TOP2A, TP73, TPD52L1, TRAF2, TRIO, TRPS1, UBB, VAV1, VDR, TRPV1, WNT11, YWHAH, YWHAZ, FOSL1, NSMAF, KLF11, PRKRA, TP63, UNC5C, AKR1C3, DYNLL1, PEA15, TRADD, RIPK1, CRADD, HRK, TNFSF12, TNFSF10, RIPK2, TNFRSF10B, TNFRSF10A, ARHGEF7, LATS1, ARHGEF2, STK17B, STK17A, SLIT2, SLC9A3R1, EIF2AK3, PPM1F, RAPGEF2, RASSF2, ARHGEF11, TNFSF15, CASP8AP2, HDAC6, PDCD6, PDCD7 |
1081 | GO:0043620 | 0.01 | 2.58 | 9.66 | 17 | 33 | regulation of DNA-templated transcription in response to stress | ARNT, ATF3, ATF4, BACH1, CHEK1, EP300, RBPJ, JUN, RPS6KA1, RPS6KA3, RPS27A, UBB, UBE2D1, UBE2D2, VEGFA, CUL2, RBX1 |
1082 | GO:0050885 | 0.01 | 2.58 | 9.66 | 17 | 33 | neuromuscular process controlling balance | ABL1, ABL2, ALDH1A3, APLP2, APP, ATP2B2, BCR, CACNA1A, TPP1, GAA, GM2A, HEXB, RAC3, TNR, CLRN1, CNTNAP1, NRXN1 |
1083 | GO:0006614 | 0.00 | 2.58 | 21.07 | 37 | 72 | SRP-dependent cotranslational protein targeting to membrane | FAU, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, SRP9, SRP14, SSR3, RPL14, RPL23, SPCS2 |
1084 | GO:0046903 | 0.00 | 2.57 | 12.37 | 22 | 44 | secretion | APRT, AQP5, ATP2B2, CACNB4, CDO1, CHRM1, CHUK, COPA, ACE, DHODH, CELSR2, SLC29A1, GUCA2B, HK2, PRKCI, PRL, STAT5B, TP73, TPD52, TRPC1, TRPC4, VDR |
1085 | GO:1901992 | 0.00 | 2.57 | 10.24 | 18 | 35 | positive regulation of mitotic cell cycle phase transition | ANXA1, BIRC5, APP, CDC6, CDK4, DDX3X, KCNA5, PTEN, RAD51C, RAD51B, RB1, SMARCD3, UBE2E2, CDC45, CUL4A, CUL3, PHOX2B, DLGAP5 |
1086 | GO:1903725 | 0.00 | 2.57 | 10.24 | 18 | 35 | regulation of phospholipid metabolic process | ARF1, SCARB1, EPHA8, PTK2B, FGFR3, FGR, FLT1, FLT3, HTR2C, IDH1, KIT, PTK2, RAC1, CCL21, ZP3, PIK3R3, KLF4, RUBCN |
1087 | GO:0030858 | 0.00 | 2.56 | 10.83 | 19 | 37 | positive regulation of epithelial cell differentiation | ACVRL1, ALOX15B, BAD, BMP4, CYP27B1, DMBT1, ETV2, GDNF, IL13, KITLG, PAX2, PROC, PTCH1, RFX3, SOX9, VDR, PTCH2, NUMB, ZEB2 |
1088 | GO:0070301 | 0.00 | 2.56 | 10.83 | 19 | 37 | cellular response to hydrogen peroxide | ABL1, ANXA1, AQP1, ARG1, EPOR, ETS1, F3, HGF, PAX2, PPP5C, PRKAA1, PSAP, PYCR1, RPS3, STAT6, KLF4, HDAC6, IL18BP, TRAP1 |
1089 | GO:0090090 | 0.00 | 2.56 | 24.58 | 43 | 84 | negative regulation of canonical Wnt signaling pathway | AES, CTNND1, RAPGEF1, IGFBP6, ISL1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS27A, SFRP5, SIAH2, SOX9, SOX10, UBB, WNT11, FZD6, CUL3, RGS20, LATS1, PSMF1, RBX1, G3BP1, PSME3, PSMD14 |
1090 | GO:0043281 | 0.00 | 2.56 | 14.81 | 26 | 51 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | APAF1, BAD, BOK, CASP9, COL4A3, CTGF, CTSH, F2R, F3, HIP1, MGMT, P2RX1, REST, RET, RPS3, S100A8, S100A9, TP63, CRADD, EIF2AK3, PPM1F, KIAA0141, TNFSF15, CASP8AP2, PDCD6, BCL2L11 |
1091 | GO:0006026 | 0.00 | 2.56 | 11.41 | 20 | 39 | aminoglycan catabolic process | CD44, VCAN, CSPG4, DCN, GPC4, GPC5, GALNS, GPC3, GPC1, HEXA, HEXB, IDS, IDUA, OMD, OVGP1, SDC1, SDC4, SLC9A1, PGLYRP1, SDC3 |
1092 | GO:0050777 | 0.00 | 2.55 | 12.56 | 22 | 43 | negative regulation of immune response | ANGPT1, ANXA1, BCR, BST2, CD59, CD55, GPX1, IFNA2, IL2RA, IL10, IL12B, IL13RA2, PSMB4, PTPN6, XCL1, STAT6, TNFSF4, CD84, PGLYRP1, TNFSF18, IL1RL1, IL27RA |
1093 | GO:0002221 | 0.00 | 2.55 | 28.10 | 49 | 96 | pattern recognition receptor signaling pathway | BIRC3, XIAP, BTK, CASP8, CD14, CD86, CD36, CHUK, CREB1, CTSK, CTSS, CYBA, DMBT1, DUSP7, ELK1, IRAK1, IRAK2, IRF1, ITGAM, JUN, LTF, PDPK1, PPP2R5D, PRKCE, MAPK1, MAPK3, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SEC14L1, SKP1, HSP90B1, TYRO3, UBB, UBE2D1, UBE2D2, UBE2V1, CUL1, IKBKG, RIPK1, RIPK2, PGLYRP1, RPS6KA5, NR1D1, PUM1, TRIL, NR1H4, TANK |
1094 | GO:0000082 | 0.00 | 2.55 | 18.84 | 33 | 65 | G1/S transition of mitotic cell cycle | ACVR1B, ANXA1, CAMK2A, CAMK2G, CCNB1, CDC25A, CDK3, CDK4, CDK6, CDKN2D, CKS1B, DDX3X, EIF4E, ITGB1, KCNA5, ORC2, ORC4, PIM1, PPP6C, PRIM2, PTPN6, RBBP8, RPA3, RPS6KB1, SKP1, SKP2, ADAM17, UBE2E2, CUL4A, CUL3, CUL2, CUL1, LATS1 |
1095 | GO:0031330 | 0.00 | 2.54 | 13.72 | 24 | 47 | negative regulation of cellular catabolic process | ACACB, ADRA1B, BCL2L1, TSPO, CNR1, DFFA, GATA4, GOLGA2, GPLD1, HGF, HP, IL10, INS, KIF25, PTPN3, SNCA, SNRNP70, STAT3, TSC1, RGN, FEZ2, KDM4A, DHX34, RUBCN |
1096 | GO:0021510 | 0.00 | 2.54 | 13.15 | 23 | 45 | spinal cord development | ACTL6A, PHOX2A, CACNA1A, DCC, EVX1, HOXC10, HOXD10, ISL1, PTCH1, PTN, PTPRS, RNF2, SOX4, SOX11, SRD5A1, TULP3, ZIC1, IFT88, CHRD, EED, SLIT2, BAG3, OLIG2 |
1097 | GO:0044784 | 0.00 | 2.54 | 13.17 | 23 | 45 | metaphase/anaphase transition of cell cycle | BUB1, BUB1B, CCNB1, CDC6, CDC20, CDC27, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, MAD2L1, PTEN, RB1, TTK, UBE2D1, ZNF207, CUL3, CDC23, CDC16, ZW10, BUB3, DLGAP5 |
1098 | GO:0051701 | 0.00 | 2.53 | 35.12 | 61 | 120 | interaction with host | ADRBK1, ALB, ANPEP, AXL, BAD, BCL2L1, CD4, CD86, SCARB1, SCARB2, CR1, CR2, CXADR, CD55, DPP4, EFNB2, EPS15, FBLN1, GYPA, ICAM1, IFIT1, IFNA2, ITGA2, ITGA5, ITGAV, ITGB1, ITGB5, KPNA1, KPNA2, KPNA3, KPNA4, LTF, SMAD3, NTRK3, NUP98, SERPINB9, PVR, RANBP2, RXRA, SELPLG, SLAMF1, SLC10A1, SLC20A2, SLC22A5, TRIM21, DYNLT1, TYMS, TYRO3, UVRAG, TRIM25, NUP214, AAAS, FCN3, VAMP8, CLDN1, XPR1, VAPB, VAPA, NUP155, NUP93, BCL2L11 |
1099 | GO:0071456 | 0.00 | 2.53 | 16.06 | 28 | 55 | cellular response to hypoxia | ADAM8, AQP1, BAD, BNIP3L, CCNB1, CLCA1, DNMT3A, SLC29A1, GATA6, GNGT1, ICAM1, IRAK1, KCND2, KCNK2, KCNK3, PRKAA1, PRKCE, PTEN, PTGIS, PTGS2, PTN, SLC2A4, SLC8A1, SLC8A3, SLC9A1, STC1, TRPC1, OGT |
1100 | GO:0006094 | 0.00 | 2.53 | 14.93 | 26 | 51 | gluconeogenesis | ALDOC, ATF3, ATF4, BPGM, SLC25A10, ENO2, G6PC, GAPDH, GCG, KAT2A, GOT2, GPD2, GPI, INS, MDH2, PCK1, PCK2, PGAM1, PRKACB, PRKACG, PTPN2, RANBP2, OGT, SLC25A12, NR1D1, SLC25A13 |
1101 | GO:0030810 | 0.00 | 2.53 | 14.93 | 26 | 51 | positive regulation of nucleotide biosynthetic process | ABCA1, ADCY7, ADCYAP1R1, AVPR2, CALM3, CRH, DRD5, EDNRA, FSHR, GCG, GHRHR, GNAS, GUCA1A, GUCA2A, GUCA2B, NTRK2, P2RY11, PTH, RAF1, RCVRN, STAT3, VIP, VIPR2, WFS1, AKAP12, GUCA1C |
1102 | GO:0050818 | 0.00 | 2.53 | 14.93 | 26 | 51 | regulation of coagulation | ABAT, ANXA5, APOH, CD36, F2, F2R, F3, F7, F12, FAP, FGA, GP1BA, FOXA2, HRG, KLKB1, KNG1, SERPINE1, PRKCQ, PRKG1, PROC, PROS1, S100A9, SELP, SYK, USF1, VTN |
1103 | GO:0071593 | 0.00 | 2.53 | 69.65 | 120 | 238 | lymphocyte aggregation | ABL1, ABL2, ADA, ADAM8, ANXA1, BAD, BAX, BCL3, BMP4, BMX, ZFP36L2, CASP8, RUNX2, CBLB, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD7, CD8A, CD28, CD86, TNFSF8, CD59, CD74, CD151, CDK6, CLC, CTLA4, CXADR, CD55, DHPS, DPP4, DTX1, EFNB1, EFNB2, EGR3, FLOT2, FLT3, FYN, GATA3, GRB2, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF2, IHH, IL2RA, IL10, IL12B, IL18, IDO1, INS, IRF1, ITGAD, ITGAL, KIT, LMO1, SMAD3, P2RX7, PDPK1, PRKAR1A, PRKCQ, PTPN2, PTPN6, RAB27A, RAC1, RAC2, RAG1, RAG2, RARA, RPL22, SATB1, CCL21, XCL1, SFTPD, SOS2, SOX4, SP3, SPTA1, SRF, STAT5B, STAT6, STK10, SYK, ADAM17, TRAF2, TSC1, TNFSF4, SCGB1A1, VAV1, WAS, WNT1, ZP3, FZD5, EOMES, FZD7, FZD8, AP3B1, PDE5A, STX11, TNFSF14, TNFSF9, RIPK2, IL1RL2, IL18R1, VNN1, AP3D1, TNFSF18, SOCS6, GRAP2, SOX13 |
1104 | GO:0072091 | 0.00 | 2.53 | 15.51 | 27 | 53 | regulation of stem cell proliferation | ARHGAP5, BMP4, BMPR1A, CTNNA1, CX3CR1, ACE, DCT, FBLN1, FGF9, IHH, KDR, KITLG, OVOL1, PTN, CX3CL1, SIX3, SMARCD3, SOX9, SOX10, SOX11, NR2E1, VEGFA, WNT11, FZD3, TP63, CHRD, PHF14 |
1105 | GO:0006446 | 0.00 | 2.52 | 17.27 | 30 | 59 | regulation of translational initiation | ATF4, DAZ1, DDX1, DDX3X, EIF2B1, EIF4A1, EIF4A2, EIF4B, EIF4EBP2, EIF4G2, EIF5, HSPB1, EIF3E, PPP1CA, DNAJC3, RARA, RBM4, RPS6KB1, RPS6KB2, RXRA, EIF4H, EIF4EBP3, EIF3F, EIF3G, EIF4G3, EIF2B3, EIF2B2, EIF2AK3, EIF5B, EIF1 |
1106 | GO:0006954 | 0.00 | 2.52 | 45.53 | 79 | 158 | inflammatory response | AGTR2, AHCY, AXL, BDKRB1, CD5L, CD14, TNFRSF8, CD40, CD44, ADGRE5, CDO1, CHUK, CCR1, CCR3, CRH, CRHBP, CSF1R, CYBA, ECM1, ELF3, F2R, FPR2, ACKR1, XCR1, CXCL2, CXCL3, HRH1, IFI16, IFNA2, RBPJ, IL1RAP, IL13, TNFRSF9, IRAK2, ITGAL, KIT, KNG1, KRT16, LIPA, LTA4H, SMAD1, NTRK2, OLR1, P2RX1, P2RX7, PF4V1, PRKD1, PRKCQ, PTAFR, PTGDR, PTGS1, RAC1, RXRA, CCL21, CCL22, CCL25, CXCL6, CXCL5, SDC1, SELP, SIGLEC1, SP100, SYK, TP73, SCG2, ATRN, TPST1, IKBKG, RIPK2, SNAP23, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, RPS6KA4, PSTPIP1, RPS6KA5, TRIL, CHST4 |
1107 | GO:0031347 | 0.00 | 2.50 | 80.41 | 138 | 278 | regulation of defense response | ADAR, AP2B1, ANXA5, ARF1, BTK, CALM3, CASP8, CD4, CD14, CD86, CD36, CD37, CHUK, AP2M1, AP1S1, AP2S1, COX8A, CREB1, CRH, CTSK, CYBA, COCH, DMBT1, DUSP7, ELK1, EP300, FGF7, FGR, FYN, GABRA5, UBE2K, HPX, ICAM2, IFI16, IFIT1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNGR1, IGF2, IRAK1, IRAK2, IRF1, ITGAM, ITPR1, ITPR3, JUN, KCNQ1, LTF, NTHL1, PCBP2, PDK4, PDPK1, PENK, PEX13, SERPINB9, PPM1B, PPP2R5D, PRKACB, PRKACG, PRKCE, MAPK1, MAPK3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMB1, PSMB2, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTPN6, PVR, RAC1, RAF1, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SERPINB4, SCN1A, SEC14L1, SKP1, SNRPD1, STAT2, SYK, TARBP2, HSP90B1, TYK2, UBB, UBE2D1, UBE2D2, UBE2V1, SUMO1, NR1H2, VAV1, ZNF189, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, CUL1, IKBKG, RIPK1, RIPK2, AP1M1, HIST1H3F, UBA3, RPS6KA5, CHST3, PSMF1, NR1D1, NUP93, PUM1, PHYHIP, TRIL, NR1H4, FGFBP1, TANK, AP1M2, PSME3, PSMD14 |
1108 | GO:0060759 | 0.00 | 2.50 | 24.29 | 42 | 83 | regulation of response to cytokine stimulus | ADAR, AES, ANGPT1, BIRC3, AXL, CASP8, CD74, CHUK, ECM1, UBE2K, HPX, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNGR1, IL1RN, IRAK1, IRAK2, PTPN2, PTPN6, RPS27A, STAT2, SYK, TNFRSF1A, TRAF1, TRAF2, TYK2, UBB, SUMO1, NR1H2, IKBKG, MADD, TRADD, RIPK1, RIPK2, TAX1BP1, SOCS3, KLF4, SLIT2 |
1109 | GO:0050795 | 0.00 | 2.50 | 33.61 | 58 | 115 | regulation of behavior | ADA, ADAM10, ALB, ANGPT2, BMPR2, CD74, CHRNB2, CCR1, CMKLR1, CRH, DRD3, S1PR1, LPAR1, EDNRA, EFNB2, F3, F7, PTK2B, FGF4, GHRHR, CXCL2, CXCL3, HRG, HSPB1, ITGA2, KDR, SMAD3, NTRK3, SERPINE1, PENK, PF4V1, PRKD1, PTPN2, RAC1, RAC2, S100A7, CCL21, CXCL6, CXCL5, XCL1, CX3CL1, SEMA3F, ADAM17, NR2C2, VEGFA, VEGFB, SCG2, SEMA3B, TNFSF14, NRP1, PER3, TNFSF18, USP14, SLIT2, NRXN1, CXCL14, PPM1F, SEMA3E |
1110 | GO:0003012 | 0.01 | 2.50 | 8.60 | 15 | 30 | muscle system process | AGTR2, CAMK2G, CYBA, GATA6, GTF2I, IGF1, TBCE, TRPC3, COL14A1, AKAP1, SORBS2, CTDP1, KLF4, AKAP6, KDM4A |
1111 | GO:0071216 | 0.00 | 2.49 | 28.39 | 49 | 97 | cellular response to biotic stimulus | ABCA1, ABL1, APAF1, ARG1, ASS1, AXL, PRDM1, BYSL, TSPO, CD6, CD14, CD86, CD36, SCARB1, ENTPD2, CD40, CEBPE, CSF2, CX3CR1, CD55, EDNRB, HMGCS2, ICAM1, IFNG, IL10, IL12B, IL18, IRAK1, IRAK2, LTF, P2RY2, SERPINE1, PDE4B, PRKCE, MAPK1, MAPK3, PTAFR, RARA, UPF1, SYK, TNFRSF1B, TNFSF4, WFS1, FZD5, OGT, RIPK2, EIF2AK3, LITAF, NR1D1 |
1112 | GO:0006955 | 0.00 | 2.49 | 30.77 | 54 | 112 | immune response | AHCY, ARHGDIB, BMPR1A, BPI, TNFRSF8, TNFSF8, CD70, ADGRE5, CCR1, CCR8, CMKLR1, CYP11B1, EDA, ETS1, GEM, CXCL2, CXCL3, GZMH, IGF1R, IK, IL1A, IL1R1, IL1RN, TNFRSF9, ITGAD, SMAD6, PF4V1, EXOSC9, PRG2, RFX1, RGS1, CXCL6, CXCL5, SP2, TNFRSF1A, TNFRSF1B, IL1R2, IKBKAP, PRKRA, S1PR4, TNFSF14, TNFSF12, TNFSF10, TNFSF9, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, CXCL14, GTPBP1, TNFSF15, COL4A3BP, CHST4, PRG4 |
1113 | GO:0009117 | 0.03 | 2.49 | 6.32 | 11 | 22 | nucleotide metabolic process | ACPP, TYMP, IDH1, MDH2, PGD, PTGIS, PTGS2, RPE, PDHX, KCNAB2, TP53I3 |
1114 | GO:0042327 | 0.00 | 2.49 | 169.45 | 284 | 579 | positive regulation of phosphorylation | ABL1, ABL2, ACVR1B, ACVR2B, ACVRL1, ADAM8, ADCY1, ADCY7, ADRA1B, ALK, ANG, ANGPT1, ARAF, ARNT, ATP6AP1, BAD, BAX, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, C3, CALM3, CAMK2A, CAMK2G, CCNB1, CCNC, CCNT2, CD3E, CD4, CD36, CD40, CD44, CD74, CDC6, CDK5, CDKN1A, CENPE, CLU, CCR1, CRH, CRKL, CSF1R, CSF2, CSF2RB, CSNK1D, CSPG4, CTF1, CTGF, ACE, DUSP5, DUSP7, DUSP9, LPAR1, EDNRA, EDNRB, EFNA1, EFNA5, EMP2, EPHA4, EPHA8, EPOR, ERCC6, F2, F2R, PTK2B, FCER1A, FGA, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FGR, FLT1, FLT3, FLT3LG, FLT4, FPR1, FSHR, FYN, GCG, GDF9, GNG3, GRB2, RAPGEF1, GRIN2A, GRM1, HCLS1, HGF, NRG1, UBE2K, HMGCR, HPX, PRMT1, HTR2C, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF1R, IGF2, IGFBP3, IL1A, IL2RA, IL2RB, IL2RG, IL3, IL12B, IL13, IL18, ILK, INHA, INS, IRAK1, ITGA6, IRAK2, ISL1, ITGA1, ITGA5, ITGB1, JUN, KDR, KISS1, KIT, LTF, MARK3, KITLG, MAP3K11, NTRK2, NTRK3, DDR2, P2RX7, PDPK1, PFN2, PHB, PIM1, PPP5C, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRKD1, MAPK1, MAPK3, PROX1, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, PTPRA, PTPRZ1, RAC1, RAF1, RAP1A, RAP2A, RAP2B, RASA2, RET, RPS3, RPS27A, RYK, S100A7, S100A12, CCL21, CCL22, CCL25, XCL1, CX3CL1, SDC4, ITSN1, SHC1, STIL, SLAMF1, SNCA, SOX9, SPTA1, SPTB, STK10, XCL2, SYK, ADAM17, TNFRSF1A, TNFRSF1B, TP73, TPD52L1, TRAF2, TTK, UBB, VEGFA, VEGFB, VTN, WNT1, WNT11, ZNF16, ZP3, LRP8, FZD5, ARHGEF5, FGF23, CDK2AP1, FZD4, FZD7, FZD8, BCAR3, CUL3, OGT, SEMA7A, IKBKG, MADD, PDE5A, PEA15, RIPK1, RIPK2, TNFRSF18, TNFRSF10B, TNFRSF10A, IQGAP1, NRP1, RPS6KA4, TNFSF18, UNC119, LATS1, ARHGEF2, BMP15, VAPB, RPS6KA5, ITGB1BP1, GPR55, KL, PSMF1, GDF15, BAG4, NRG2, TRAF4, RAPGEF2, SLK, RASSF2, ATG13, RB1CC1, ZEB2, OXSR1, TNFSF15, RBX1, RAD50, AKAP9, RASA4, PSME3, PSMD14 |
1115 | GO:0002253 | 0.00 | 2.48 | 83.99 | 143 | 287 | activation of immune response | ABL1, ACTB, ADA, ADAM8, BIRC3, XIAP, BAX, BLK, BTK, C3, C7, CACNB4, CALM3, CASP8, CBLB, CD3D, CD3E, CD3G, CD4, CD14, CD28, CD86, CD36, CD59, CHUK, CLU, CR1, CR2, CREB1, CTLA4, CTSK, CTSS, CYBA, CD55, DMBT1, DUSP7, ELF1, ELK1, EP300, FCGR2A, FCN2, FGR, FYB, FYN, GATA3, GPLD1, GRB2, CFHR1, ICAM2, IFI16, IRAK1, IRAK2, IRF1, ITGAM, ITPR1, ITPR3, JUN, KCNN4, LIMK1, LTF, PDE4B, PDPK1, CFP, PHB, PPP2R5D, PRKACB, PRKACG, PRKCB, PRKCE, PRKCQ, MAPK1, MAPK3, PROS1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, PTPN2, PTPN6, PTPRJ, RAC1, RAF1, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, SEC14L1, SKP1, SYK, HSP90B1, TYRO3, UBB, UBE2D1, UBE2D2, UBE2V1, VAV1, VTN, WAS, LAT2, CUL1, IKBKG, FCN3, RIPK1, RIPK2, PGLYRP1, UBA3, RPS6KA5, GRAP2, PSMF1, BCAR1, NR1D1, PUM1, TRIL, NR1H4, TANK, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, WASF2, PSME3, PSMD14 |
1116 | GO:0055082 | 0.00 | 2.48 | 106.24 | 180 | 363 | cellular chemical homeostasis | ABCB7, ABL1, ABL2, ADCYAP1R1, ADRA1B, AGTR1, AGTR2, ALAS2, ANXA6, APLP2, APP, ARF1, ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP4A, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, AVPR1B, BAD, BAX, BDKRB1, BMP4, CACNA1A, CACNB4, CALM3, CASQ1, CASQ2, CAV3, CD4, CD36, CD40, CD52, CLCN3, CLN5, CCR1, CCR3, CCR8, CRH, CYBA, CD55, DIAPH1, DRD3, DRD5, S1PR1, LPAR1, EDNRA, EDNRB, EFNA5, SLC29A1, EPHA5, EPOR, F2, F2R, PTK2B, FTL, GALR1, GATA4, GCG, GHRHR, GNA15, GNAT2, GNG3, GPLD1, XCR1, GRINA, GRM1, GTF2I, HEXB, HK2, HMGCR, FOXA2, HPX, HRC, HTR2C, ICAM1, IGF1, IGF1R, IL1R1, IL13, IREB2, ITGB1, ITPR1, ITPR3, KCNA5, KCNJ2, KCNJ11, KCNK3, KISS1, KNG1, LTF, MEN1, NUBP1, NTSR1, OXCT1, OXTR, P2RX3, P2RX4, P2RX5, P2RX7, P2RY2, P2RY4, PAX2, PDPK1, SERPINF1, PLN, PPT1, PRKCB, PRKCE, PRKD1, PTH, PTPN6, PTPRN, PTPRN2, PYGM, RAF1, RANBP2, RAP1A, RHAG, RYR1, RYR2, S100A8, S100A9, SCO1, CCL21, XCL1, SGK1, SLC4A1, SLC8A1, SLC8A3, SLC9A1, SMARCA4, SNCA, SOX4, SRF, STC1, TNNI3, TPT1, HSP90B1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, VDR, TRPV1, WFS1, SLC30A1, SLC30A2, FGF23, OGT, S1PR4, INPP4B, AP3D1, ATP6V0E1, RGN, ATP6V0D1, XPR1, VAPB, RAB11B, HMGN3, SLC9A3R1, NRXN1, GSTO1, AKAP6, ATG5, ATP6V1G1, NR1D1, ATP2C2, NR1H4, ABCB6, SGK2 |
1117 | GO:0007420 | 0.00 | 2.47 | 40.02 | 69 | 140 | brain development | ABAT, ABL1, ABL2, ACAT1, AGTR2, AK2, ARCN1, ARF4, RERE, ATP2B1, ATP2B2, BCR, BMPR2, BOK, BRCA2, BYSL, CACNA1A, CD9, CENPF, CLN5, CTNS, CTNND1, DNMT1, S1PR1, CELSR2, EGR2, EML1, EPOR, AFF2, GABRA5, GRID2, H3F3B, HMGCS2, HMX2, FOXA2, HNMT, ID1, IGF1, IGF1R, ITGB1, KCNK3, MEN1, OXCT1, PAX2, PPT1, PTCH1, QARS, SEPP1, SMARCA1, STXBP3, SYT1, SYT4, NR2C2, TULP3, UBE3A, WRN, ZIC1, KCNAB1, FZD4, ATRN, UNC5C, PHOX2B, ATP6V0D1, NRXN1, SLC4A7, BAG3, AATK, BCL2L11, ABCB6 |
1118 | GO:0071407 | 0.00 | 2.47 | 28.39 | 49 | 99 | cellular response to organic cyclic compound | ABCA1, ABL1, ADAR, ADCY1, BAD, BYSL, CASP8, CCNB1, CDH1, COL1A1, CTNNA1, CYBA, DNM2, DRD5, FGA, GNAI1, GNAS, GPLD1, ID1, IFIT1, IL18, JUP, KCNJ11, SMAD1, SMAD3, SMAD9, MGMT, P2RX4, P2RX7, P2RY6, P2RY11, PDE4B, PTCH1, PTGS2, RAD51, RPS6KB1, SHMT1, SLC6A4, SLC9A1, SLC34A1, SNCA, STAT3, TARBP2, HSP90B1, TRPV1, LRP8, PRKRA, RGS20, KLF4 |
1119 | GO:0090087 | 0.02 | 2.46 | 7.52 | 13 | 26 | regulation of peptide transport | BCL3, EDA, IL10, IL12B, IL18, PRDX1, PPM1B, PRKCQ, PTGS2, TRIP6, TNFSF14, IL18R1, LITAF |
1120 | GO:0048878 | 0.00 | 2.46 | 13.22 | 23 | 47 | chemical homeostasis | CNR1, CRY2, CTSH, CYP11B1, DBH, DHPS, FGF7, GCGR, FFAR1, IDUA, OAS1, PCK1, PRCP, PTCH1, PTPN2, RPS6, SFTPD, SLC2A4, SLC12A1, SOD2, STAT3, HNF1A, VEGFA |
1121 | GO:0007584 | 0.00 | 2.46 | 14.50 | 25 | 50 | response to nutrient | ABCA1, AHCY, ALB, APAF1, ASS1, BRCA2, CD3E, CHAT, CNR1, DAD1, ENSA, GCGR, HMGCR, HMGCS2, IGF1, OXCT1, PTEN, RPS6KB1, SLC6A4, SLC8A1, SUOX, OGT, HAT1, AKR1C3, LIPG |
1122 | GO:0017038 | 0.02 | 2.46 | 7.53 | 13 | 26 | protein import | CLU, HSPA4, LAMP2, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX19, PEX5, PEX16, TOMM20 |
1123 | GO:0008283 | 0.00 | 2.46 | 52.93 | 92 | 195 | cell proliferation | ADRA1B, ALK, AMBN, BIN1, TNFRSF17, BOK, ZFP36L2, BST2, BUB1, BUB1B, BYSL, CD5, TNFSF8, SCARB1, CD70, CDK11B, CDC25A, CDC25C, CDC27, CDK3, CDK5, CENPF, CHRM3, CHUK, CKS1B, CLK1, CSE1L, CSPG4, DKC1, DMBT1, E4F1, EPHA2, ELN, ENPEP, EPS15, ERG, ETV6, GPC4, GCG, KAT2A, GNAT1, HDGF, HLCS, IFI16, IL15RA, INSIG1, ISG20, KRT2, KRT16, LIPA, MKI67, MAP3K11, PA2G4, PRDX1, PCNA, ABCB1, PIM1, PPP1R8, PRKX, PRL, PURB, RAC1, REG1B, RPL23A, RPS6KA1, RPS27, SETMAR, STIL, SIPA1, FSCN1, SP2, STAT4, TSPY1, TYMS, TYR, UBE2L3, MIA, PICALM, GFI1B, BLZF1, CREG1, CDC16, EIF2S2, USP8, ARHGEF1, AURKB, COPS2, LIPG, BCAR1, DLGAP5, GINS1, COL4A3BP |
1124 | GO:0007369 | 0.03 | 2.45 | 6.39 | 11 | 22 | gastrulation | ACVR2B, APLNR, DLD, FGF8, HHEX, IL1RN, OTX2, RNF2, ZBTB17, CUL3, ARFRP1 |
1125 | GO:0031099 | 0.00 | 2.45 | 12.80 | 22 | 44 | regeneration | ANXA1, BCL9, TSPO, CCNB1, CTNNA1, DHFR, EPHA4, GFAP, GPX1, IGF1, ISL1, JUN, NTRK3, PRKCQ, PTEN, PTPN12, RXRA, TNR, FZD7, ADAM15, KLF4, CHST3 |
1126 | GO:0032940 | 0.00 | 2.45 | 78.85 | 134 | 273 | secretion by cell | ABCA1, ACTN4, ACTN1, ACVR2B, AGTR1, ALB, SLC25A4, ANXA3, APP, AQP1, ARL2, ARNTL, AXL, CACNA1A, CACNA1B, CALM3, CAMK2A, CAMK2G, CANX, CD9, CD36, CD40, CD63, CHAT, CHRM3, CHRNB4, CLU, CCR1, CRP, CTGF, EFNA5, ENSA, EPHA5, FGF7, GAD1, GCGR, GDF9, B4GALT1, GNAS, HGF, FOXA2, HRG, HTR2C, IGF2, RBPJ, IL1RN, ITPR1, ITPR3, KCNA5, KCNC2, KCNS3, KIT, KNG1, LAMP2, LLGL2, LTBP2, RAB8A, NTRK2, P2RX1, SERPINE1, PAM, PCSK5, PDPK1, PFN2, PIK3C2A, PPT1, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PROS1, PSAP, PTPRN, PTPRN2, RAB1A, RAB3B, RAC2, RAF1, RALA, RFX3, S100A12, S100A13, SELP, SLC1A6, SLC2A2, SLC6A13, SLC22A2, SNAP25, SPARC, SPINK1, STXBP2, SYN1, SYT5, HNF1A, TNFAIP2, TRAF2, TUBA4A, TYRO3, VCL, VEGFA, VEGFB, VIP, TRPV1, LAT2, SCG2, SYN3, FZD4, LTBP4, STX11, SNAP23, LIN7A, IQGAP1, SYNJ1, DGKI, RAB11B, HMGN3, SNAP29, NRXN3, NRXN1, NRXN2, EIF2AK3, ATG5, NR1D1, CLOCK, SNCAIP, RIMS2, RIMS3, SPCS2, SCRN1, WDR1, RABEPK, ABCC4 |
1127 | GO:0010556 | 0.02 | 2.45 | 6.86 | 12 | 25 | regulation of macromolecule biosynthetic process | ACTN4, ACTN1, CTGF, DTX1, F2, FCER2, HAS2, HPN, KDR, NSMAF, SERPINB7, TRIP11 |
1128 | GO:0001763 | 0.00 | 2.45 | 31.02 | 53 | 106 | morphogenesis of a branching structure | AGTR2, RERE, BAX, PRDM1, BMP4, CAV3, CD44, CTNND2, CTSH, EDNRA, EPHA2, ETV4, ETV5, FGF7, FGF8, FOXD1, GDNF, B4GALT1, GPC3, GRB2, HGF, HHEX, FOXA2, IGF1, IHH, IL10, ILK, KDR, LLGL2, PAX2, PGR, PPP1CA, PSPN, PROX1, PTCH1, RXRA, SALL1, SLC12A2, SOX9, SOX10, SRF, ST14, VDR, VEGFA, WNT1, FZD5, TP63, NRP1, SOCS3, SLIT2, SEMA3E, FEM1B, SPRY1 |
1129 | GO:0019083 | 0.00 | 2.45 | 30.44 | 52 | 104 | viral transcription | EP300, ERCC3, FAU, HPN, JUN, NUP98, RANBP2, REST, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, SMARCA4, SP1, SP100, TRIM21, SSRP1, TARBP2, USF1, NUP214, AAAS, RPL14, CTDP1, RPL23, NUP155, NUP93 |
1130 | GO:0033273 | 0.03 | 2.44 | 6.40 | 11 | 22 | response to vitamin | ADA, ALAD, TSPO, CCNE1, COL1A1, F7, HLCS, HMBS, ITGA2, SPARC, KYNU |
1131 | GO:0044724 | 0.00 | 2.44 | 16.93 | 29 | 58 | single-organism carbohydrate catabolic process | ALDOC, ARNT, BAD, BPGM, ENO2, FUT6, FUT8, GALE, GAPDH, GK2, GM2A, GPD2, GPI, HEXB, HK2, IGF1, OGDH, P2RX7, PFKFB4, PGAM1, PGK2, PPP2R5D, PRKAA1, PRKAG1, RPE, SORD, STAT3, OGT, XYLB |
1132 | GO:0048167 | 0.00 | 2.44 | 15.76 | 27 | 54 | regulation of synaptic plasticity | ARF1, ATP2B2, CAMK2A, CDC20, CDK5, CTNND2, DBN1, DRD5, EGR2, EIF4EBP2, GRIA1, HRH1, KCNJ10, KIT, RAB8A, P2RX3, PTGS2, RAB3A, RARA, SRF, SYP, CNTN2, YWHAH, DGKI, PICK1, RIN1, RAPGEF2 |
1133 | GO:0071248 | 0.01 | 2.44 | 11.08 | 19 | 38 | cellular response to metal ion | AQP1, ATF4, TSPO, CCNB1, CD86, CDH1, CREB1, CYP1A2, CYP11B1, GLRA1, ID2, KCNA1, KCNJ1, KCNK3, SERPINF1, PPP5C, SLC34A1, SNCA, EIF2AK3 |
1134 | GO:0042129 | 0.00 | 2.44 | 24.58 | 42 | 84 | regulation of T cell proliferation | ANXA1, BMP4, CBLB, CD3E, CD4, CD6, CD28, CD86, CD59, CLC, CD55, DHPS, EFNB1, IFNG, IGF1, IGF2, IHH, IL2RA, IL10, IL12B, IL18, IDO1, IRF1, ITGAL, LMO1, PRKAR1A, PRKCQ, PTPN6, RAC2, XCL1, SFTPD, SOS2, SPTA1, STAT5B, SYK, TNFSF4, SCGB1A1, ZP3, PDE5A, TNFSF9, RIPK2, TNFSF18 |
1135 | GO:0032526 | 0.02 | 2.44 | 6.99 | 12 | 24 | response to retinoic acid | ASCL1, BMP4, CDKN2D, CTSH, DUSP1, IGF2R, PTCH1, RNF2, RXRA, SP100, SREBF1, SLC10A3 |
1136 | GO:0051591 | 0.01 | 2.44 | 9.91 | 17 | 34 | response to cAMP | BSG, CDK2, CDO1, COL1A1, DUSP1, PTK2B, HMGCS2, JUN, JUNB, JUND, PTPRN, PYGM, SDC1, SPARC, SREBF1, TYR, FOSL1 |
1137 | GO:0044070 | 0.03 | 2.44 | 6.41 | 11 | 22 | regulation of anion transport | AGTR2, ARG1, ATP1A2, CACNA1A, CRH, CRY2, GPM6B, STC1, SYK, FGF23, RAB11B |
1138 | GO:0045814 | 0.00 | 2.44 | 21.66 | 37 | 74 | negative regulation of gene expression, epigenetic | DNMT1, DNMT3A, DNMT3B, ERCC3, HIST1H2AD, H3F3B, HMGA1, JARID2, PHF2, RBBP4, TBP, TTF1, ARID1A, HIST1H4I, CDC45, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, HAT1, EED, SAP30, HIST1H3F, HIST1H2AG, TAF1B, TAF1A |
1139 | GO:0009411 | 0.01 | 2.44 | 11.09 | 19 | 38 | response to UV | BCL3, BRCA2, CAT, CDKN2D, CIRBP, ERCC3, ERCC6, FEN1, GPX1, HMGN1, IL12B, IVL, MEN1, SERPINB13, PRKAA1, TYR, USF1, WRN, XPA |
1140 | GO:0030802 | 0.00 | 2.44 | 16.37 | 28 | 56 | regulation of cyclic nucleotide biosynthetic process | ABCA1, ADCY7, ADCYAP1R1, AVPR2, CALM3, CRH, DRD3, DRD5, LPAR1, EDNRA, EDNRB, FSHR, GALR1, GCG, GHRHR, GNAI3, GNAS, NTRK2, P2RY11, PALM, PTH, RAF1, VIP, VIPR2, WFS1, AKAP6, GABBR2, AKAP12 |
1141 | GO:2000241 | 0.02 | 2.43 | 7.59 | 13 | 26 | regulation of reproductive process | ACVR1B, CDC20, GDF9, B4GALT1, GLRA1, GPR3, PPP2R1A, PTAFR, RXRA, SOX9, SPINK1, SRY, PDE5A |
1142 | GO:0071482 | 0.02 | 2.43 | 8.17 | 14 | 28 | cellular response to light stimulus | CALM3, CNGA1, CRY2, FNTA, GNAT1, GNGT1, GUCA1A, GUCY2F, GUCY2D, PRKCQ, RCVRN, RPGR, RGS9, GUCA1C |
1143 | GO:0048813 | 0.03 | 2.43 | 7.00 | 12 | 24 | dendrite morphogenesis | ABL2, RERE, CACNA1A, CELSR2, FYN, HPRT1, ITGB1, RAC1, PICALM, KLF7, DCLK1, FARP1 |
1144 | GO:0051347 | 0.00 | 2.43 | 120.58 | 202 | 412 | positive regulation of transferase activity | ABL1, ACVR2B, ADAM8, ADCY1, ADCY7, ALK, ANG, ANGPT1, ARAF, BAD, BAX, BMI1, BMP4, CALM3, CAMK2A, CAMK2G, CCNB1, CCNC, CCNT2, CD4, CD40, CD74, CDC6, CDC20, CDC27, CDK5, CDKN1A, CENPE, CLU, CRKL, CSF1R, CSF2, CSF2RB, CSPG4, ACE, DKC1, DUSP5, DUSP7, DUSP9, LPAR1, EFNA1, EFNA5, EMP2, EPHA4, EPHA8, ERCC6, F2R, PTK2B, FCER1A, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FGR, FLT1, FLT3, FPR1, FYN, GCG, GNG3, GRB2, RAPGEF1, GRIN2A, GRM1, HGF, NRG1, IGF2, IL2RA, IL2RB, IL2RG, IL3, IL12B, ILK, INS, IRAK1, IRAK2, ITGA1, KIT, LTF, MARK3, KITLG, MAP3K11, NTRK3, DDR2, NVL, P2RX7, PDPK1, PIM1, PPP5C, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCQ, MAPK1, MAPK3, PROX1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, PTPRA, RAC1, RAF1, RAP1A, RASA2, RPS3, RPS27A, S100A12, CCL21, SDC4, SHC1, STIL, SKP1, SNCA, SORL1, SPTA1, SPTB, STK10, SYK, ADAM17, TP73, TPD52L1, TRAF2, UBB, UBE2D1, UBE2L3, VEGFA, WNT11, ZNF16, ZP3, LRP8, FZD5, ARHGEF5, FGF23, FZD4, FZD8, CUL3, CUL1, IKBKG, CDC14B, MADD, PDE5A, TNKS, PEA15, CDC23, RIPK1, RIPK2, TNFRSF10B, TNFRSF10A, IQGAP1, CDC16, UNC119, AURKB, VAPB, ITGB1BP1, KLF4, KL, PSMF1, NRG2, TRAF4, RAPGEF2, SLK, RASSF2, ATG13, ZEB2, EPM2AIP1, OXSR1, TNFSF15, RBX1, RAD50, AKAP9, RASA4, PSME3, PSMD14 |
1145 | GO:0002700 | 0.03 | 2.43 | 6.42 | 11 | 22 | regulation of production of molecular mediator of immune response | CD28, CD37, CD40, HPX, IFNG, IL13, IL13RA2, STAT6, UNG, TNFSF13, IL27RA |
1146 | GO:1903649 | 0.00 | 2.43 | 34.01 | 58 | 117 | regulation of cytoplasmic transport | ABL1, ACTL6A, ADCYAP1R1, ARF1, ATP1A2, BAX, BDKRB1, BNIP3L, CASQ1, CD4, CSNK2A2, CTSK, CYBA, DIAPH1, EDNRA, F2, F2R, PTK2B, GAS1, KAT2A, GPR26, NRG1, HNMT, HRC, IL13, P2RX3, P2RX4, P2RX5, P2RX7, PDPK1, PRKCE, PRKD1, MAPK1, MAPK3, PSMB7, PSMD8, PTPN6, RAC2, RNASE2, RPL28, RYR2, XCL1, SLC8A1, SNCA, SORL1, SREBF1, TRPC1, TRPC3, UBE2L3, ZBTB17, FZD5, BAP1, RUVBL1, CDKL2, ATG5, ATG13, FAM20B, SAE1 |
1147 | GO:0010676 | 0.04 | 2.43 | 5.84 | 10 | 20 | positive regulation of cellular carbohydrate metabolic process | ADCYAP1R1, ARNT, BAD, HRH1, NTSR1, P2RX7, PRKAA1, PRKCE, PTAFR, SNCA |
1148 | GO:0030593 | 0.01 | 2.43 | 8.77 | 15 | 30 | neutrophil chemotaxis | CXADR, IFNG, ITGA1, ITGA9, PDE4B, S100A8, S100A9, S100A12, CCL22, CCL25, CX3CL1, XCL2, SYK, VAV1, SLIT2 |
1149 | GO:0042990 | 0.00 | 2.43 | 14.05 | 24 | 48 | regulation of transcription factor import into nucleus | AGTR2, BCL3, CD36, CDH1, EDA, HCLS1, IL10, IL12B, IL18, SMAD3, TONSL, PRDX1, PPM1B, PRKCQ, PTGS2, SLC9A1, TRIP6, AKAP1, DYRK2, TNFSF14, IL18R1, AKAP6, LITAF, TRIM28 |
1150 | GO:0051306 | 0.00 | 2.43 | 14.05 | 24 | 48 | mitotic sister chromatid separation | BUB1, BUB1B, CCNB1, CDC6, CDC20, CDC27, CENPE, CENPF, CSNK2A1, CSNK2A2, DUSP1, MAD2L1, PPP2R1A, PTEN, RB1, TTK, UBE2D1, ZNF207, CUL3, CDC23, CDC16, ZW10, BUB3, DLGAP5 |
1151 | GO:0030500 | 0.04 | 2.43 | 5.84 | 10 | 20 | regulation of bone mineralization | BGLAP, CCR1, CYP27B1, ECM1, S1PR1, PTK2B, DDR2, OMD, SOX9, FGF23 |
1152 | GO:0031623 | 0.00 | 2.43 | 13.46 | 23 | 46 | receptor internalization | ADRBK1, ANGPT1, ARF1, CAV3, CD9, CD36, CD63, CLTC, DNM1, DNM2, DRD3, GRB2, GRIA1, ITGB1, RAB5A, SELE, SNCA, SYK, CNTN2, VEGFA, PICALM, PICK1, RAMP3 |
1153 | GO:0015908 | 0.00 | 2.43 | 12.29 | 21 | 42 | fatty acid transport | ACACB, AGTR2, ABCD1, ANXA1, SLC25A20, CD36, CPT1B, CPT2, ACE, DRD3, GOT2, NTSR1, P2RX4, P2RX7, P2RY2, PRKAB2, ABCD3, SLCO2A1, SYK, CYP4F2, ABCC4 |
1154 | GO:0030819 | 0.00 | 2.43 | 11.71 | 20 | 40 | positive regulation of cAMP biosynthetic process | ABCA1, ADCY7, ADCYAP1R1, AVPR2, CALM3, CRH, DRD5, EDNRA, FSHR, GCG, GHRHR, GNAS, NTRK2, P2RY11, PTH, RAF1, VIP, VIPR2, WFS1, AKAP12 |
1155 | GO:0051149 | 0.00 | 2.43 | 11.71 | 20 | 40 | positive regulation of muscle cell differentiation | ABL1, BMP4, CAV3, CDH15, CTH, CTNNA1, EFNB2, FLT3LG, NRG1, IGFBP3, RBPJ, ILK, NTN3, PROX1, RBM4, SMARCD3, NR2C2, TNFSF14, AKAP6, GDF15 |
1156 | GO:0006757 | 0.01 | 2.43 | 11.12 | 19 | 38 | ATP generation from ADP | ALDOC, ARNT, BPGM, ENO2, GAPDH, GPI, HK2, IGF1, INS, OGDH, P2RX7, PFKFB4, PGAM1, PGK2, PPP2R5D, PRKAA1, PRKAG1, STAT3, OGT |
1157 | GO:0042311 | 0.01 | 2.43 | 11.12 | 19 | 38 | vasodilation | AGTR1, AGTR2, CPS1, CRP, ACE, EDNRB, GPX1, HMGCR, INS, ITGA1, KCNJ8, KNG1, P2RX4, P2RY2, PRKG1, PTAFR, SOD2, VIP, ATG5 |
1158 | GO:0050830 | 0.01 | 2.43 | 11.12 | 19 | 38 | defense response to Gram-positive bacterium | ANG, APP, TNFSF8, CD36, CRP, CTSG, FAU, FCN2, FGR, P2RX7, RNASE3, RPL39, ADAM17, VIP, HIST1H2BF, HIST2H2BE, RIPK2, PGLYRP1, IL27RA |
1159 | GO:0055013 | 0.02 | 2.43 | 7.60 | 13 | 26 | cardiac muscle cell development | AGTR2, CAV3, CCNB1, GATA4, PROX1, SGCB, SLC8A1, SRF, COL14A1, SORBS2, CTDP1, AKAP6, ATG5 |
1160 | GO:0010043 | 0.01 | 2.43 | 10.54 | 18 | 36 | response to zinc ion | ALAD, ARG1, ASS1, BGLAP, TSPO, CPS1, CREB1, GLRA1, HMBS, KCNK3, KRT14, LTA4H, P2RX7, PLN, PTEN, S100A8, SLC30A1, SLC30A2 |
1161 | GO:0035567 | 0.01 | 2.43 | 9.95 | 17 | 34 | non-canonical Wnt signaling pathway | ABL1, ABL2, CSNK1D, CELSR2, GPC4, FZD2, RAC1, RYK, SFRP5, WNT11, FZD5, FZD3, FZD4, FZD6, FZD7, FZD8, FZD9 |
1162 | GO:2000278 | 0.01 | 2.43 | 9.95 | 17 | 34 | regulation of DNA biosynthetic process | ACVRL1, BMPR2, CDKN1A, DKC1, DUSP1, PTK2B, HGF, KCNK2, MEN1, NVL, PRKCQ, MAPK1, MAPK3, TNKS, RGN, AURKB, KLF4 |
1163 | GO:0019748 | 0.01 | 2.43 | 9.37 | 16 | 32 | secondary metabolic process | ARL1, ASIP, BPGM, AKR1C4, CTNS, CYP1A2, CYP2A6, CYP11B1, DCT, PAM, PGAM1, TRPC1, TYR, AKR1C3, RAPGEF2, ZEB2 |
1164 | GO:0032024 | 0.01 | 2.43 | 9.37 | 16 | 32 | positive regulation of insulin secretion | ABAT, BAD, BLK, CRH, GCG, GLUD1, GPLD1, FFAR1, ISL1, OXCT1, PRKCE, PSMD9, SOX4, TRH, TRPM2, NR0B2 |
1165 | GO:2001244 | 0.01 | 2.43 | 9.37 | 16 | 32 | positive regulation of intrinsic apoptotic signaling pathway | BAD, BAX, BCL2L1, BUB1, CLU, PTPN2, RPS3, S100A8, S100A9, SFPQ, TP73, UBB, PRKRA, SLC9A3R1, EIF2AK3, BCL2L11 |
1166 | GO:0030512 | 0.01 | 2.42 | 8.78 | 15 | 30 | negative regulation of transforming growth factor beta receptor signaling pathway | DNM2, FBN1, ONECUT1, SMAD3, SMAD6, SMAD7, PDPK1, PPP1CA, RPS27A, ADAM17, UBB, WNT1, ZFYVE9, ONECUT2, ADAMTSL2 |
1167 | GO:0050810 | 0.01 | 2.42 | 8.78 | 15 | 30 | regulation of steroid biosynthetic process | ATP1A1, TSPO, CYP27B1, DHCR7, IFNG, INSIG1, PRKAA1, PROX1, REST, SNAI1, SREBF1, VDR, AKR1C3, NR1D1, NR1H4 |
1168 | GO:1903146 | 0.01 | 2.42 | 8.78 | 15 | 30 | regulation of mitophagy | ACTL6A, BNIP3L, TSPO, CSNK2A2, CTSK, CTTN, KAT2A, RPL28, SREBF1, VDAC1, ZBTB17, FZD5, RUVBL1, ATG5, HDAC6 |
1169 | GO:0030003 | 0.00 | 2.42 | 83.12 | 140 | 284 | cellular cation homeostasis | ABCB7, ABL1, ABL2, ADCYAP1R1, ADRA1B, AGTR1, AGTR2, ALAS2, ANXA6, APLP2, APP, ARF1, ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP4A, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, AVPR1B, BAX, BDKRB1, BMP4, CACNA1A, CACNB4, CALM3, CASQ1, CASQ2, CAV3, CD4, CD36, CD40, CD52, CLCN3, CLN5, CCR1, CCR3, CCR8, CYBA, CD55, DIAPH1, DRD3, DRD5, S1PR1, LPAR1, EDNRA, EDNRB, EPOR, F2, F2R, PTK2B, FTL, GALR1, GNA15, GNAT2, GNG3, XCR1, GRINA, GRM1, GTF2I, HEXB, HPX, HRC, HTR2C, IL13, IREB2, ITGB1, ITPR1, ITPR3, KCNA5, KCNJ2, KCNK3, KISS1, KNG1, LTF, NUBP1, NTSR1, OXTR, P2RX3, P2RX4, P2RX5, P2RX7, P2RY2, P2RY4, PDPK1, PLN, PPT1, PRKCB, PRKCE, PRKD1, PTH, PTPN6, PYGM, RYR1, RYR2, S100A8, S100A9, SCO1, CCL21, XCL1, SGK1, SLC8A1, SLC8A3, SLC9A1, SNCA, STC1, TNNI3, TPT1, HSP90B1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, VDR, TRPV1, WFS1, SLC30A1, SLC30A2, S1PR4, INPP4B, AP3D1, ATP6V0E1, RGN, ATP6V0D1, VAPB, GSTO1, AKAP6, ATG5, ATP6V1G1, ATP2C2, ABCB6, SGK2 |
1170 | GO:0006968 | 0.02 | 2.42 | 8.19 | 14 | 28 | cellular defense response | CD5L, CCR3, CX3CR1, PTK2B, ITGB1, KLRC3, LSP1, TYROBP, ZNF148, VEZF1, FOSL1, KLRC4, PAGE1, IL1RL2 |
1171 | GO:0048546 | 0.02 | 2.42 | 8.19 | 14 | 28 | digestive tract morphogenesis | ACVR2B, BMP4, EPHB3, FGFR3, GATA4, ID2, IHH, SMAD3, SFRP5, SOX10, SOX11, TP73, WNT11, TP63 |
1172 | GO:0009250 | 0.02 | 2.42 | 7.61 | 13 | 26 | glucan biosynthetic process | GYS2, IGF1, IGF2, INS, PHKG1, PPP1CA, PPP1R3C, PTH, RPS27A, UBB, DYRK2, NR1D1, EPM2AIP1 |
1173 | GO:0032760 | 0.02 | 2.42 | 7.61 | 13 | 26 | positive regulation of tumor necrosis factor production | CD14, TNFRSF8, CD36, CLU, CYBA, HSPB1, IFNG, IL12B, ISL1, PTAFR, RIPK1, RIPK2, ARHGEF2 |
1174 | GO:0045840 | 0.02 | 2.42 | 7.61 | 13 | 26 | positive regulation of mitotic nuclear division | BIRC5, CD28, DRD3, FGF8, IGF1, IGF1R, IGF2, IL1A, INS, PTEN, RB1, CUL3, DLGAP5 |
1175 | GO:0050432 | 0.02 | 2.42 | 7.61 | 13 | 26 | catecholamine secretion | ABAT, ADRBK1, AGTR2, CHRNB2, CNR1, CRH, DRD3, GDNF, FFAR3, OXTR, PCP4, PTGS1, SNCA |
1176 | GO:0051496 | 0.02 | 2.42 | 7.61 | 13 | 26 | positive regulation of stress fiber assembly | CTGF, LPAR1, LIMK1, SMAD3, PFN2, PRKCQ, RAC1, SDC4, WNT11, ARHGEF5, ITGB1BP1, BAG4, PPM1F |
1177 | GO:0090102 | 0.02 | 2.42 | 7.61 | 13 | 26 | cochlea development | ATP2B2, FGFR3, FZD2, GABRA5, GABRB2, HPN, KCNK2, KCNK3, NTRK3, PAX2, RAC1, SOX9, IFT88 |
1178 | GO:0035306 | 0.03 | 2.42 | 7.02 | 12 | 24 | positive regulation of dephosphorylation | AGTR2, CALM3, GPLD1, IFNG, ITGA1, ITGA2, SMAD3, PPP1R12A, PPP1R7, SMPD1, RGN, AKAP6 |
1179 | GO:0051926 | 0.03 | 2.42 | 7.02 | 12 | 24 | negative regulation of calcium ion transport | ATP1A2, CALM3, CASQ2, CAV3, ICAM1, NTSR1, PLN, PTGS2, SPINK1, STC1, SLC30A1, GSTO1 |
1180 | GO:1901570 | 0.03 | 2.42 | 7.02 | 12 | 24 | fatty acid derivative biosynthetic process | ANXA1, CBR1, CD74, FCER1A, GGT7, HPGD, LTA4H, PTGIS, PTGS1, PTGS2, SYK, AKR1C3 |
1181 | GO:0009409 | 0.03 | 2.42 | 6.44 | 11 | 22 | response to cold | ATP2B1, CASP8, CDH8, CIRBP, IMPDH1, P2RX3, PRKAA1, DNAJC3, TRH, EIF2AK3, ZNF516 |
1182 | GO:0016445 | 0.03 | 2.42 | 6.44 | 11 | 22 | somatic diversification of immunoglobulins | CD28, CD40, IFNG, IL10, STAT6, TNFSF4, UNG, TNFSF13, RNF8, EXO1, IL27RA |
1183 | GO:0031128 | 0.03 | 2.42 | 6.44 | 11 | 22 | developmental induction | BMP4, FGF3, FGF8, GDNF, HOXC11, SALL1, SIX3, SOX9, WNT1, FZD5, SPRY1 |
1184 | GO:0046461 | 0.03 | 2.42 | 6.44 | 11 | 22 | neutral lipid catabolic process | APOH, DAGLA, CPS1, FABP2, FABP7, GPLD1, LIPC, LIPE, PPP1CA, PRKACB, PRKACG |
1185 | GO:0001910 | 0.04 | 2.42 | 5.85 | 10 | 20 | regulation of leukocyte mediated cytotoxicity | ICAM1, IGF2, IL12B, P2RX7, SERPINB9, PVR, SERPINB4, XCL1, STAT5B, VAV1 |
1186 | GO:0002323 | 0.04 | 2.42 | 5.85 | 10 | 20 | natural killer cell activation involved in immune response | IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IL12B, RAB27A, STX11, PGLYRP1 |
1187 | GO:0031343 | 0.04 | 2.42 | 5.85 | 10 | 20 | positive regulation of cell killing | BAD, FCER2, IFNG, IL12B, P2RX7, PVR, XCL1, STAT5B, VAV1, BCL2L11 |
1188 | GO:0033014 | 0.04 | 2.42 | 5.85 | 10 | 20 | tetrapyrrole biosynthetic process | ALAD, ALAS2, TSPO, COX15, CPOX, HMBS, SPTA1, SPTB, UROS, ABCB6 |
1189 | GO:0045124 | 0.04 | 2.42 | 5.85 | 10 | 20 | regulation of bone resorption | ADAM8, ATP6AP1, BGLAP, CSF1R, S1PR1, FSHB, IAPP, P2RX7, PDK4, SYK |
1190 | GO:0050931 | 0.04 | 2.42 | 5.85 | 10 | 20 | pigment cell differentiation | CD63, EDNRB, GNAQ, KIT, KITLG, RAB27A, SOX10, AP1M1, AP3D1, ZEB2 |
1191 | GO:0051653 | 0.04 | 2.42 | 5.85 | 10 | 20 | spindle localization | CENPA, DYNC1H1, LLGL2, NUMA1, DYNLT1, ARHGEF2, ZW10, ACTR3, ACTR2, SPRY1 |
1192 | GO:2000249 | 0.04 | 2.42 | 5.85 | 10 | 20 | regulation of actin cytoskeleton reorganization | ABL1, ABL2, CDK5, CSF1R, DAPK3, PTK2B, HCLS1, NTRK3, GMFG, SEMA3E |
1193 | GO:1901988 | 0.00 | 2.41 | 35.41 | 60 | 121 | negative regulation of cell cycle phase transition | BUB1, BUB1B, CCNB1, CDC20, CDC27, CDK2, CDKN1A, CENPF, CSNK2A1, CSNK2A2, DUSP1, MAD2L1, MEN1, FOXO4, OVOL1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, RB1, RPA2, RPS27A, SMARCA4, SOX4, SOX11, TP73, TTK, UBB, UBE2D1, ZNF207, TP63, CDC23, CRADD, CDC16, ZW10, BUB3, PSMF1, CTDSP2, PSME3, PSMD14, CTDSPL |
1194 | GO:0043010 | 0.00 | 2.40 | 24.15 | 41 | 83 | camera-type eye development | ALDH1A3, AQP1, AQP5, BFSP1, CDK2, CDK4, CRYAB, CRYBA1, CRYBA4, CRYGB, CTNS, EPHA2, FBN1, EFEMP1, FGFR3, GATA3, GPD2, HMGN1, HSF4, JUN, KDR, LIM2, SMAD3, NTRK3, RARA, RCN1, RXRA, SOX11, SP1, SP3, SRF, TULP3, VEGFA, VIM, YY1, FZD5, ARID1A, BCAR3, KLF4, ZEB2, MFN2 |
1195 | GO:0050900 | 0.00 | 2.40 | 17.62 | 30 | 61 | leukocyte migration | ADA, ANGPT1, ANGPT2, BCR, BSG, CD44, CD58, COL1A1, DBH, F2, FYN, B4GALT1, GRB2, GRB7, ITGA6, ITGA5, ITGAL, ITGAM, ITGAV, ITGB1, OLR1, PROC, PROS1, PTPN6, SELL, SELPLG, SHC1, SLC7A5, CD84, DOK2 |
1196 | GO:0006928 | 0.00 | 2.40 | 192.13 | 317 | 681 | movement of cell or subcellular component | ACTB, AP2B1, AGTR1, ANG, APBB2, APP, ARAF, ARF4, ASCL1, ASTN1, RERE, KIF1A, AXL, BAX, BICD1, DST, BSG, TSPO, CACNB1, CACNB2, CACNB4, CALM3, CAMK2A, CAMK2G, CAV3, CD9, CD44, CD58, CD72, ADGRE5, CD151, CENPE, CHN1, AP2M1, AP2S1, COL2A1, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF2, CSF2RB, CSNK2A1, CSNK2A2, VCAN, CSPG4, CTGF, CXADR, DBH, DCC, DLG3, DLX5, DNM1, DNAH8, DYNC1H1, DPP4, DUSP5, DUSP7, DUSP9, EDNRB, EFNA3, EFNA4, EFNA5, EFNB1, EFNB2, CELSR2, EGR2, EGR3, CTTN, EMX2, ENPEP, EPHA3, EPHA4, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, ERG, ETV1, ETV4, F2, FAP, FGF3, FGF6, FGF8, FGF9, FGFR3, FPR1, FPR2, FPR3, FUT8, FYN, GAS8, GDNF, GFRA1, GPC1, GPM6A, GPR15, GPX1, GRB2, GRIN2A, HIST1H1T, HEXB, NR4A1, HRH1, ID1, IL2RA, IL2RB, IL2RG, IL3, IL10, IL12B, IL13, ING2, ITGA6, ISL1, ITGA1, ITGA7, ITGA9, ITGAL, ITGAM, KCNA5, KCNH2, KCNQ1, KIF5A, KIF25, KRT2, LDHC, LIMK1, LSP1, MAP1B, MARK3, SMCP, MYO1B, NRCAM, NTRK2, NTN3, OGDH, OLR1, OPA1, OPHN1, OTX2, PALM, PAX3, PCM1, PEX7, PEX13, PGK2, SERPINB5, SERPINI2, PIK3C2A, PIK3C2B, PPP5C, PRKCI, PRKCQ, PRKG1, MAPK3, PSPN, PROC, PROS1, PSG2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTPN6, PTPRA, RAB1A, RAB6A, RASA2, RFX3, RPGR, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RYK, S100A2, S100A8, S100A9, S100A12, S100P, SAA4, SCN2B, SCN4B, SCNN1B, CCL22, SDC1, SELL, SELPLG, SFTPD, ITSN1, SHC1, SIAH2, SIX3, SLC9A1, FSCN1, SNTA1, SORD, SOS2, SOX10, SPG7, SPOCK1, SPTA1, SPTB, XCL2, SYK, T, CNTN2, NR2F1, TNNC2, TNNI2, TNNI3, TNR, TNS1, TOP2B, TPM2, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TYK2, TYRO3, TYROBP, UBB, CLRN1, VAV1, VIM, DNALI1, LRP8, SCG2, FZD3, ARHGEF5, FGF23, AP3B2, SLC7A5, USP9X, USP9Y, UXT, CUL3, SORBS2, CNTNAP1, AP3B1, KLF7, SSNA1, DYNLL1, PEA15, TNFSF12, CD84, AKAP4, VNN2, VNN1, SGPL1, PHOX2B, AP3D1, RPS6KA4, DOK2, PSTPIP1, DCLK1, RPS6KA5, KL, NRXN3, KIF3B, NRXN1, PSMF1, NRG2, CDC42BPB, NUP155, FEZ2, SDC3, IFT140, DLGAP5, ARHGEF11, ZEB2, GAB2, KIAA0319, RBX1, RANBP9, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, KIF20A, AKAP9, ABI2, RASA4, WASF2, CHST4, PSME3, PSMD14 |
1197 | GO:0009653 | 0.00 | 2.40 | 35.37 | 61 | 131 | anatomical structure morphogenesis | APLNR, ANG, ANPEP, PHOX2A, BCL3, BICD1, KLF5, BYSL, COL15A1, CSPG4, CST6, DLD, DUSP1, TYMP, EGR3, ELK3, ENPEP, EYA4, ETS2, EZH1, F2R, FAP, GPI, GPLD1, GPX1, GSC2, NR4A1, HPGD, HSBP1, IL18, ITGB5, JUNB, KRT35, LAMA3, MEOX2, MFGE8, CNOT2, PRCP, PTPRJ, RNF2, S100A7, SAT1, SHB, SRPK2, NR2F2, TNFAIP2, TPD52, VTN, XRCC2, ZBTB17, VEZF1, ZP3, SCG2, CLTCL1, FZD8, RGS20, DYRK1B, EIF2AK3, SOX13, SLC12A6, ARFRP1 |
1198 | GO:0051674 | 0.00 | 2.39 | 211.88 | 346 | 724 | localization of cell | ABL1, ABL2, ACTN4, ACVR1B, ACVRL1, ADA, ADAM8, ADAM10, AGTR1, AGTR2, ALOX15B, ANG, ANGPT1, ANGPT2, ANXA1, ANXA3, ANXA5, APBB2, APOH, AQP1, ARF4, ARHGAP4, ARHGAP5, ARHGDIB, ASCL1, ASTN1, RERE, AXL, BAX, BBS4, BCR, BDKRB1, BMP4, BMPR2, DST, BSG, BST2, TSPO, KRIT1, SCARB1, CD44, CD58, CD63, CD74, CD151, CDK5, CDK6, CCR1, CMKLR1, COL1A1, CSF1R, VCAN, CSPG4, CTGF, CTNNA1, CTSH, CX3CR1, CXADR, DAPK3, DBH, DCC, DCN, ACE, DIAPH1, DNAH8, DPEP1, DPP4, DPYSL3, ECM1, S1PR1, LPAR1, EDNRA, EDNRB, EFNA1, EFNB1, EFNB2, CELSR2, EGR3, EPHA2, EMP2, CTTN, EMX2, ENPEP, EPHA3, EPHA4, EPHA8, EPHB1, EPHB3, ERG, ETS1, F2, F2R, F3, F7, F10, PTK2B, FAP, FBLN1, EFEMP1, FGF4, FGF7, FGF8, FGR, FLT1, FLT4, FSHB, FUT8, FYN, GAS8, GATA3, GDNF, B4GALT1, GPLD1, GPM6A, GPR15, GPX1, GRB2, GRB7, CXCL2, CXCL3, HIST1H1T, HAS1, HAS2, HEXB, HGF, NRG1, NR4A1, ONECUT1, HRH1, HRG, HSPB1, ICAM1, ID1, IFNG, IGF1, IGF1R, IGFBP3, IL10, IL12B, ILK, ING2, INS, ITGA6, ISL1, ITGA1, ITGA2, ITGA4, ITGA5, ITGA7, ITGA9, ITGAL, ITGAM, ITGAV, ITGB1, JUN, JUP, KDR, KIT, KRT2, KRT16, LAMA3, LAMA4, LDHC, SMAD3, SMAD7, SMCP, KITLG, NRCAM, NTRK2, NTRK3, DDR2, OGDH, OLR1, OPHN1, P2RY2, P2RY6, SERPINE1, PAX3, PCM1, PDE4B, PDPK1, SERPINF1, PEX7, PEX13, PF4V1, PFN2, PGK2, PIK3C2A, PIK3C2B, PRCP, PRKCE, PRKCI, PRKD1, PRKCQ, PRKG1, MAPK1, PRKX, PROC, PROS1, PROX1, PSG2, PTAFR, PTEN, PTGS2, PTK2, PTN, PTPN6, PTPRJ, PTPRR, PTPRZ1, RAB1A, RAC1, RAC2, RAF1, RAP2A, RAP2B, RET, RFX3, RPS6KB1, RPS19, RRAS, S100A2, S100A7, S100A8, S100A9, S100A12, S100P, SAA4, SCNN1B, CCL21, CCL22, CCL25, CXCL6, CXCL5, XCL1, CX3CL1, SDC1, SDC4, SELE, SELL, SELP, SELPLG, SEMA3F, SFTPD, SGK1, SHC1, SIX3, SLC8A1, SLC9A1, SNAI1, FSCN1, SORD, SORL1, SOX9, SOX10, SP100, SPARC, SPOCK1, SRF, STAT3, STAT5B, STC1, STK10, XCL2, SYK, T, ADAM17, CNTN2, NR2F1, NR2F2, NR2E1, TNR, TNS1, TOP2B, TRIP6, TYK2, TYRO3, CLRN1, VAV1, VCL, VEGFA, VEGFB, VIL1, VTN, WAS, WNT11, ZP3, PTP4A1, LRP8, SCG2, SEMA3B, FZD3, ARHGEF5, SLC7A5, MADCAM1, USP9X, USP9Y, SOX14, CUL3, SORBS2, SEMA7A, IKBKAP, UNC5C, CHRD, NUMB, DNAH11, TNFSF14, TNFSF12, ADAM15, TNFRSF18, NRP2, NRP1, CD84, AKAP4, ARHGEF7, SGPL1, PHOX2B, TNFSF18, DOK2, PSTPIP1, RGN, DCLK1, ITGB1BP1, KLF4, SLIT2, SLC9A3R1, ONECUT2, BAG4, CXCL14, BCAR1, CDC42BPB, PPM1F, SDC3, RAPGEF2, SEMA3E, SLK, ZEB2, GAB2, KIAA0319, HDAC6, PDCD6, PTPRU, ARPC5, ABI2, WASF2, RNF41 |
1199 | GO:0006413 | 0.00 | 2.39 | 22.43 | 38 | 77 | translational initiation | EIF1AX, EIF4E, FAU, EIF6, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, DDX3Y, EIF2S2, RPL14, RPL23 |
1200 | GO:0006959 | 0.00 | 2.39 | 27.22 | 46 | 93 | humoral immune response | ANG, APP, KLK3, BCL3, BST2, C3, C7, CD28, CD37, CD59, CLU, CR1, CR2, CD55, DMBT1, FAU, FCER2, FCN2, FGA, GATA3, GPI, CFHR1, HPX, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, RBPJ, LTF, CFP, PHB, PROS1, PTPN6, RNASE3, RPL39, SLPI, VIP, VTN, ZP3, HIST1H2BF, HIST2H2BE, FCN3, EXO1 |
1201 | GO:0043207 | 0.00 | 2.39 | 142.23 | 235 | 486 | response to external biotic stimulus | ABCA1, ABL1, ACTA2, ADAR, ADH5, AP2B1, ALAD, ANG, ANXA3, ANXA5, BIRC3, APP, KLK3, ARF1, ARG1, ASS1, ATP4B, AXL, BAD, BCL2L1, BCL3, BCR, BDKRB1, PRDM1, BNIP3L, BPI, BST2, BYSL, TSPO, CASP8, CASP9, CD4, CD6, CD8A, CD14, CD28, CD86, TNFRSF8, TNFSF8, CD36, SCARB1, CD37, ENTPD2, CD40, CDK6, CEBPE, CHUK, AP2M1, AP1S1, AP2S1, CLU, CNP, CNR1, COMT, COX8A, CPS1, CRP, CSF2, CTSG, CX3CR1, CXADR, CYBA, CYP1A2, CYP27B1, CD55, DCN, DDX1, DDX3X, COCH, DMBT1, DNMT1, EDNRA, EDNRB, F2R, F3, FAU, FCN2, FGA, FGF7, FGR, FYN, GABRA5, GATA3, GPX1, CXCL2, CXCL3, HMGCS2, HMGA1, HP, HRG, HSPB1, ICAM1, IFI16, IFIT1, IFIT3, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNGR1, IFNW1, IGF1, RBPJ, IL2RA, IL10, IL10RA, IL12B, IL12RB2, IL13, TNFRSF9, IL18, IDO1, IRAK1, IRAK2, IRF1, IRF5, ISG20, JUN, JUNB, JUND, KCNJ8, KCNQ1, LTF, SMAD3, NRF1, NTHL1, OAS1, OAS3, ODC1, P2RX7, P2RY2, SERPINE1, PCBP2, PDE4B, PDK4, PENK, PEX13, PF4V1, CFP, SERPINB9, PPM1B, PRG2, PRKCE, MAPK1, MAPK3, DNAJC3, PROS1, PSMA2, PTAFR, PTGER1, PTGER2, PTGS2, RAB1A, RAC1, RARA, UPF1, RNASE3, RPL39, RPS6KA3, RPS6KB1, S100A7, S100A8, S100A9, S100A12, SCN1A, CCL22, CXCL6, CXCL5, XCL1, SEC14L1, SELE, SELP, SFTPD, SLPI, SNCA, SNRPD1, SPARC, STAT2, STAT5B, SYK, ADAM17, TARBP2, TNFRSF1A, TNFRSF1B, TPT1, TNFSF4, SCGB1A1, VIL1, VIP, TRIM25, ZNF189, FZD5, FOSL1, CHAF1B, HIST1H2BF, HIST2H2BE, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, OGT, PPM1D, PARG, IKBKG, FCN3, PRKRA, OASL, RIPK2, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, AP1M1, HIST1H3F, PGLYRP1, SOCS3, DDX21, DCLK1, IL27RA, CHST3, ATG5, ADAMTS4, LITAF, NR1D1, NUP93, PUM1, PHYHIP, NR1H4, FGFBP1, BCL2L11, AP1M2, ABCC9, IL18BP |
1202 | GO:0022407 | 0.00 | 2.38 | 60.29 | 101 | 206 | regulation of cell-cell adhesion | ABAT, ABL1, ABL2, ADA, ADAM8, ANXA1, ASS1, BAD, BMP4, CBLB, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD28, CD86, CD44, CD59, CD74, CDH1, CLC, CTLA4, CD55, DHPS, DPP4, DTX1, EFNA5, EFNB1, EFNB2, CELSR2, EGR3, EPHB3, FGA, FLOT2, FYN, GATA3, GRB2, HAS2, FOXA2, IFNA2, IFNG, IGF1, IGF2, IHH, IL1RN, IL2RA, IL10, IL12B, IL18, IDO1, ITGA6, IRF1, ITGA4, ITGAL, LMO1, SMAD7, PDPK1, PRKAR1A, PRKCQ, PRKG1, PTAFR, PTK2, PTPN2, PTPN6, RAC1, RAC2, RAG1, RAP1GAP, RARA, CCL21, CCL25, XCL1, CX3CL1, SFTPD, SOS2, SPTA1, STAT5B, SYK, TNR, TRAF2, TNFSF4, SCGB1A1, VAV1, WNT1, ZP3, AP3B1, PDE5A, TNFSF14, TNFSF9, RIPK2, IL1RL2, VNN1, AP3D1, TNFSF18, SOCS6, KLF4, GRAP2, SOX13, PIEZO1 |
1203 | GO:0090596 | 0.00 | 2.38 | 17.74 | 30 | 61 | sensory organ morphogenesis | ATP2B2, BCR, COL2A1, COL11A1, DLX5, EPHB2, FGF3, FGF8, FGF9, FZD2, GATA3, HMX2, HPN, INSIG1, KRT13, OTX1, MAPK1, MAPK3, RAC1, RPL38, SALL1, CLRN1, WNT1, ZIC1, FZD3, FZD6, PRKRA, HESX1, NRP1, SLC9A3R1 |
1204 | GO:0007179 | 0.00 | 2.37 | 19.56 | 33 | 67 | transforming growth factor beta receptor signaling pathway | ACVRL1, BMPR1A, CAV3, CBL, CCNC, CCNT2, CDK8, CREB1, E2F5, FNTA, FSHB, FUT8, GDF9, HPGD, ID1, ING2, ITGB5, JUN, JUNB, LTBP2, SMAD1, SMAD9, MEN1, SERPINE1, PTK2, SOX11, SP1, KLF10, UBE2D1, USP9X, USP9Y, LTBP4, GDF15 |
1205 | GO:0043524 | 0.00 | 2.37 | 20.78 | 35 | 71 | negative regulation of neuron apoptotic process | ADAM8, ANGPT1, AXL, BAX, BCL2L1, CACNA1A, EPOR, F2R, PTK2B, FGF8, FYN, GABRA5, GABRB2, GDNF, GPI, ILK, ISL1, JUN, NTF4, NTRK2, PCP4, PPT1, PRKCI, SET, ITSN1, SNCB, SNCA, SOD2, PRDX2, TP73, TYRO3, VEGFB, WFS1, XRCC2, NRP1 |
1206 | GO:0006333 | 0.00 | 2.37 | 18.38 | 31 | 63 | chromatin assembly or disassembly | HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, HIST1H2BB, HIST1H1A, HMGA1, SET, SMARCA4, SMARCC1, SMARCD3, SMARCE1, SOX9, TAL1, TSPY1, CHAF1B, ARID1A, HIST1H2BL, HIST1H2BN, HIST1H2BM, HIST1H2BF, HIST1H2BH, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H3F, BAZ1B |
1207 | GO:0001701 | 0.00 | 2.37 | 41.08 | 69 | 141 | in utero embryonic development | ACVR1B, ACVRL1, ADAM10, ADAR, ADD1, ANGPT1, ARNT, ASCL2, BCL2L1, PRDM1, BMPR1A, BTF3, CASP8, CCNB1, CSF2, DDX5, DSC3, EDNRA, EMX1, FUT8, GATA3, GATA4, GATA6, KAT2A, GRB2, HHEX, FOXA2, RBPJ, IHH, IL10, ITGA4, ITGB1, LLGL2, SMAD3, YBX1, OCRL, P2RY2, MAPK1, PTCH1, PTPRR, RBBP6, RCN1, RXRA, SRSF1, STIL, SLC8A1, SNAI1, SOX5, SOX10, SP2, ST14, NR2F2, KDM6A, VEGFA, XRCC2, SLC30A1, FZD5, FOSL1, USP9X, CUL4A, COPS3, EIF2S2, SOCS3, CCNB2, SLIT2, APBA3, BCL2L11, COL4A3BP, TRIM28 |
1208 | GO:0030522 | 0.00 | 2.37 | 45.95 | 77 | 157 | intracellular receptor signaling pathway | ACTN4, NR0B1, AHR, ALOX15B, BIRC3, XIAP, APP, ARNT, ARNTL, BCL2L1, CASP8, CCNE1, CHUK, CRY2, CYP27B1, DDX5, EP300, ESRRG, FLT1, NR5A2, GHRHR, NR4A1, HNF4G, IGF1, IRAK1, IRAK2, ISL1, SCGB2A1, CNOT2, P2RX7, PGR, PHB, PIM1, PPP5C, PRCP, PTGIS, RAN, RARA, RARB, RB1, RNF6, RPS27A, RXRA, RXRG, SEC14L1, SKP2, SMARCA4, SP100, STAT3, TAF7, NR2F1, NR2F2, NR2C1, UBB, UBE2V1, UBE3A, NR1H2, VDR, YWHAH, NRIP1, ARID1A, IKBKG, AKR1C3, RIPK2, BUD31, PSTPIP1, TRIP4, NR1D1, CLOCK, RNF14, PUM1, ZNF536, NR1I3, NR1H4, NR1D2, NR2E3, HDAC6 |
1209 | GO:0007613 | 0.00 | 2.37 | 20.19 | 34 | 69 | memory | ADCY1, ATP1A3, CHAT, CHRNB2, CNR1, COMT, CREB1, CTNS, CX3CR1, DBH, EIF4EBP2, FEN1, GRIA1, GRIN2A, HRH1, IGF1, IGF2, ITGA5, ITPR3, KCNK2, NTF4, NTRK2, OXTR, SERPINF1, PTEN, PTGS1, PTGS2, RPS6KB1, SGK1, SLC6A4, SLC8A3, SRF, RIN1, RCAN2 |
1210 | GO:0072511 | 0.00 | 2.36 | 63.51 | 106 | 217 | divalent inorganic cation transport | ABL1, ADCYAP1R1, ANXA5, ANXA6, ATP1A2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, BAX, BDKRB1, BMP4, TSPO, CACNA1A, CACNA1B, CACNB1, CACNB2, CACNB4, CACNG1, CALM3, CAMK2A, CAMK2G, CASQ1, CASQ2, CAV3, CD4, CDK5, CHRNB2, CLCA1, CCR1, CRH, CTGF, CYBA, CYP27B1, DIAPH1, EDNRA, F2, F2R, PTK2B, FYN, GCG, GIF, GJA4, GPM6A, XCR1, FFAR1, GRIN2A, HRC, HTR2C, ICAM1, IGF1, IL13, ITGAV, ITPR1, ITPR3, KCNJ2, KCNN4, NTSR1, P2RX1, P2RX3, P2RX4, P2RX5, P2RX7, PDE4B, PDPK1, PIK3C2A, PLN, PRKCB, PRKCE, PRKD1, PTGS2, PTPN6, RCVRN, RYR1, RYR2, S100A1, CCL21, XCL1, SLC8A1, SLC8A3, SLC9A1, SNCA, SPINK1, STC1, TPT1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, SUMO1, VDAC1, VDR, TRPV1, WFS1, SLC30A1, SLC30A2, ZP3, TUSC3, CD84, RGN, GSTO1, AKAP6, ATG5, ATP2C2, RAMP3 |
1211 | GO:1901564 | 0.00 | 2.36 | 62.85 | 106 | 225 | organonitrogen compound metabolic process | ACPP, ACY1, ARSA, STS, ARSD, ARSE, ARSF, ATP1A2, ATP2B2, ATP6V1B2, BAD, BAX, CACNA1A, CACNB4, CHRNB2, COX8A, CRAT, CTRB1, DBI, DCT, DIO1, DLG2, DLG3, SARDH, DNMT1, DNMT3A, DNMT3B, FZD2, G6PC, GIF, GPLD1, GRIN2A, HGF, HLCS, HMGCR, HPN, HPX, ITIH1, ITIH2, ITIH4, KIT, MKI67, P4HA1, PEPD, PIM1, PPP2R1A, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTGDR, ABCD4, RRM1, SDHC, SFTPB, SLC6A6, SLC6A8, SLC7A4, SLC34A1, SLC22A5, SNCB, SRD5A1, STAT5B, SULT1E1, SULT1A3, SULT1C2, SULT2B1, TACR3, TAZ, TRH, TYR, UQCRC1, UQCRC2, UQCRH, VEGFA, SLC7A5, VNN2, VNN1, SLC5A6, P4HA2, COX5A, PSMF1, SNCAIP, SPOCK2, NR1H4, PSME3, PSMD14 |
1212 | GO:1903706 | 0.00 | 2.36 | 13.63 | 23 | 47 | regulation of hemopoiesis | ADA, ADAM8, AXL, BAD, PRDM1, BTK, CD28, CD86, ACE, EGR3, FLT3LG, GATA3, IL2RA, PTPN6, RAG1, SYK, AP3B1, TNFSF9, RIPK2, IL1RL2, VNN1, AP3D1, SOX13 |
1213 | GO:0045619 | 0.00 | 2.36 | 16.64 | 28 | 57 | regulation of lymphocyte differentiation | ADA, ADAM8, AXL, BAD, PRDM1, BTK, CD28, CD86, EGR3, FLT3LG, GATA3, IFNG, IL2RA, IL12B, PTPN6, RAG1, RARA, SOS2, STAT5B, SYK, AP3B1, TNFSF9, RIPK2, IL1RL2, VNN1, AP3D1, SOX13, RNF41 |
1214 | GO:0045665 | 0.00 | 2.36 | 31.61 | 53 | 108 | negative regulation of neuron differentiation | APP, ARHGAP4, ASCL1, CDK5, DCC, DDX6, DPYSL3, DTX1, LPAR1, EDNRB, EFNA1, EIF4E, EPHA4, EFEMP1, GDI1, GFAP, FOXA2, ID1, ID2, ISL1, ITGB1, PTEN, PTK2, PTPRZ1, RAP1GAP, REST, RNF6, SEMA3F, SIX3, SLC6A4, SOX3, SOX9, SPOCK1, CNTN2, NR2E1, TNR, TP73, TTC3, VIM, YWHAH, SEMA3B, NRP1, PHOX2B, ARHGEF1, CBFA2T2, SLIT2, BAG5, AATK, RAPGEF2, SEMA3E, ZNF536, KIAA0319, OLIG2 |
1215 | GO:1900371 | 0.00 | 2.36 | 17.25 | 29 | 59 | regulation of purine nucleotide biosynthetic process | ABCA1, ADCY7, ADCYAP1R1, AVPR2, CALM3, CRH, DRD3, DRD5, LPAR1, EDNRA, EDNRB, FSHR, GALR1, GCG, GHRHR, GNAI3, GNAS, NTRK2, P2RY11, PALM, PTH, RAF1, STAT3, VIP, VIPR2, WFS1, AKAP6, GABBR2, AKAP12 |
1216 | GO:0042107 | 0.00 | 2.35 | 17.85 | 30 | 61 | cytokine metabolic process | BCL3, CD3E, CD4, CD28, CD86, TNFRSF8, CEBPE, CEBPG, FCER1A, GATA3, GHSR, HSPB1, IFNG, IL1A, IL1RAP, IL10, IL12B, IL18, INHA, IRF1, PCSK5, PRG2, PRKCQ, PTAFR, SFTPD, STAT5B, SYK, KLF4, TNFSF15, PRG4 |
1217 | GO:0002478 | 0.00 | 2.35 | 31.02 | 52 | 106 | antigen processing and presentation of exogenous peptide antigen | AP2B1, ARF1, CANX, CD36, CD74, CENPE, AP2M1, AP1S1, AP2S1, CLTC, CTSE, CTSS, CYBA, DYNC1H1, DNM2, ITGAV, ITGB5, KIF5A, ABCB1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS27A, UBB, DYNLL1, CTSF, AP1M1, KIF3B, PSMF1, AP1M2, ACTR1A, PSME3, PSMD14 |
1218 | GO:0031324 | 0.00 | 2.35 | 59.86 | 101 | 216 | negative regulation of cellular metabolic process | BIRC3, XIAP, APLP2, APP, AQP1, BST2, C3, CASP8, CCNC, CD44, CD59, CLU, COL4A3, COL6A3, COMT, CR1, CRYAB, CST1, CST6, CD55, DPEP1, ECM1, SERPINB1, F2, FYN, IFI6, GAS1, GPC3, GPI, GPX1, HK2, HRG, DNAJB2, ITGAV, ITIH1, ITIH2, ITIH4, KNG1, LIMK1, SERPINE1, SERPINA5, SERPINF1, SERPINA4, SERPINB5, SERPINB6, SERPINB9, SERPINI1, SERPINB13, SERPINI2, PRKCE, PROS1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PZP, RAF1, RAG1, RENBP, RPS6KA1, RPS6KA3, SERPINB4, SLPI, SNTA1, SOX4, SPOCK1, SERPINA7, TRAF2, USP4, VDAC1, VIL1, VTN, PICALM, SERPINB7, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, ATG5, FRY, TRAP1, PSME3, PSMD14 |
1219 | GO:0001816 | 0.01 | 2.35 | 10.06 | 17 | 35 | cytokine production | ABCA1, AVPR2, CEBPE, CD55, DBH, RBPJ, IL1RAP, KIT, LIPA, PCSK5, RAB1A, S100A8, S100A9, S100A12, S100A13, EOMES, ADAMTS3 |
1220 | GO:0002573 | 0.00 | 2.35 | 14.86 | 25 | 51 | myeloid leukocyte differentiation | BGLAP, CD86, CHUK, CSF2, EPHA2, FSHB, FSHR, GATA3, GPC3, GLO1, HHEX, RBPJ, JUNB, KIT, LTF, RARA, TAL1, TYROBP, CUL4A, TNFSF9, INPP4B, GPR55, RASSF2, GAB2, DHRS2 |
1221 | GO:0009124 | 0.00 | 2.35 | 16.68 | 28 | 57 | nucleoside monophosphate biosynthetic process | ADA, ADSS, AK1, AK2, AMPD1, AMPD2, APRT, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V0A1, DHODH, HPRT1, IMPDH1, IMPDH2, LDHC, PFAS, PRPS2, SHMT1, STAT3, TYMS, UPP1, SLC25A13 |
1222 | GO:0048639 | 0.00 | 2.35 | 15.48 | 26 | 53 | positive regulation of developmental growth | ACACB, BBS4, C3, CCNB1, CREB1, EFNA5, FGF8, GATA4, GATA6, GHRHR, GHSR, IGF1, IGF2, RBPJ, PPIB, PROX1, RAG2, RPS6KB1, STAT5B, SYT1, SYT4, VIL1, ZP3, RND2, AKAP6, RIMS2 |
1223 | GO:0044106 | 0.00 | 2.35 | 40.09 | 67 | 137 | cellular amine metabolic process | ABAT, ARG1, ARG2, ASL, ASS1, ALDH7A1, BCHE, BHMT, SCARB1, CHAT, CHKA, CHKB, CHRNB2, CKM, COMT, CPS1, DBI, DHPS, FGF7, GATA3, GATM, GPLD1, HPN, HPRT1, IDO1, INS, LCAT, LIPC, OAZ1, OAZ2, ODC1, PCYT1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, SAT1, SLC6A8, SMPD1, SMS, SNCA, TACR3, TRH, KYNU, PSMF1, NR1H4, SLC25A15, PSME3, PSMD14 |
1224 | GO:0045637 | 0.00 | 2.35 | 29.27 | 49 | 100 | regulation of myeloid cell differentiation | ACVR1B, ARNT, ATP6AP1, BGLAP, CASP8, CDK6, CCR1, CREB1, CSF1R, ETS1, PTK2B, FSHB, FSHR, GNAS, HCLS1, PRMT1, ID2, IFNG, IL3, IL12B, INHA, JUN, LTF, KITLG, PTPN2, PURB, RARA, RB1, STAT5B, TAL1, KLF10, TYROBP, ZNF16, HIST1H4I, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, OGT, RIPK1, INPP4B, GPR55, RASSF2, RNF41 |
1225 | GO:0071902 | 0.00 | 2.35 | 38.29 | 64 | 131 | positive regulation of protein serine/threonine kinase activity | ADAM8, ALK, CALM3, CCNC, CCNT2, CD40, CD74, CDC6, CSF1R, CSPG4, DUSP5, DUSP7, DUSP9, LPAR1, EFNA1, EPHA4, ERCC6, PTK2B, FCER1A, FLT1, FLT3, FPR1, GNG3, GRM1, HGF, IGF2, ILK, IRAK2, ITGA1, KIT, LTF, KITLG, MAP3K11, NTRK3, P2RX7, PIM1, PRKAA1, MAPK1, MAPK3, PROX1, RPS3, RPS27A, S100A12, SHC1, STIL, SNCA, SYK, ADAM17, TP73, TPD52L1, UBB, VEGFA, FZD5, ARHGEF5, FZD4, FZD8, MADD, PDE5A, PEA15, RIPK1, RIPK2, IQGAP1, RAPGEF2, ZEB2 |
1226 | GO:0003206 | 0.00 | 2.34 | 15.51 | 26 | 53 | cardiac chamber morphogenesis | CAV3, COL11A1, FGF8, FZD2, GATA3, GATA4, GATA6, NRG1, ID2, RBPJ, ISL1, SMAD7, PROX1, RARA, RARB, RXRA, RYR2, SMARCD3, SOX4, SOX11, SRF, TNNC1, TNNI3, WNT11, IFT88, HAND1 |
1227 | GO:0006090 | 0.00 | 2.34 | 15.51 | 26 | 53 | pyruvate metabolic process | ALDOC, ARNT, BPGM, BSG, DLD, ENO2, GAPDH, GLO1, GPI, HK2, IGF1, INS, LDHC, OGDH, P2RX7, PCK1, PDK4, PFKFB4, PGAM1, PGK2, PPP2R5D, PRKAA1, PRKAG1, STAT3, PDHX, OGT |
1228 | GO:0009179 | 0.00 | 2.34 | 15.51 | 26 | 53 | purine ribonucleoside diphosphate metabolic process | AK1, AK2, ALDOC, ARNT, BAD, BPGM, ENTPD2, DLG2, DLG3, ENO2, GAPDH, GPI, GUK1, HK2, IGF1, INS, OGDH, P2RX7, PFKFB4, PGAM1, PGK2, PPP2R5D, PRKAA1, PRKAG1, STAT3, OGT |
1229 | GO:0043065 | 0.00 | 2.34 | 56.98 | 95 | 197 | positive regulation of apoptotic process | ABL1, ADAM8, AES, ALDH1A3, BIN1, ANXA1, ANXA5, APBB1, APBB2, ARHGAP4, BARD1, BCL2A1, BMP4, BNIP3L, TSPO, CAMK2A, TNFRSF8, CD40, CDK4, CNR1, COL4A3, CREB1, CRYBA1, CTGF, CTLA4, DDX3X, DFFA, DHODH, DNM2, DUSP1, LPAR1, ERCC3, F2R, F3, FGD1, GPLD1, GRIN2A, HIP1, HMGCR, HRG, IFNG, IGF2R, IGFBP3, IL10, IL12B, IDO1, ING2, ITGA6, IRF5, ITGB1, KNG1, NTRK3, NTSR1, P2RX1, P2RX7, PPID, PRKCI, PTGS2, PTN, RAC1, RARB, REST, RPS6, RPS6KA2, RPS27A, RXRA, SORT1, ITSN1, SLC9A1, SMPD1, SNCA, SOS2, SOX4, TOP2A, TRIO, VAV1, TRPV1, WNT11, FOSL1, NSMAF, KLF11, UNC5C, AKR1C3, RIPK2, ARHGEF7, LATS1, ARHGEF2, SLIT2, PPM1F, RAPGEF2, RASSF2, ARHGEF11, TNFSF15, CASP8AP2, PDCD6 |
1230 | GO:0043488 | 0.00 | 2.34 | 26.92 | 45 | 92 | regulation of mRNA stability | ZFP36L2, CIRBP, ELAVL1, GDNF, HNRNPC, HSPB1, YBX1, EXOSC9, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, UPF1, RPS27A, SET, UBB, SCGB1A1, VIP, YWHAZ, NUP214, ANP32A, KHSRP, TNFSF13, PSMF1, PUM1, PSME3, PSMD14 |
1231 | GO:0003279 | 0.00 | 2.34 | 14.93 | 25 | 51 | cardiac septum development | AP2B1, PRDM1, BMP4, DNM2, FGF8, FZD2, GATA3, GATA4, GATA6, ID2, ISL1, SMAD6, SMAD7, PCSK5, PROX1, RARA, RARB, SALL1, SOX4, SOX11, WNT11, IFT88, TRIP11, HAND1, SNX17 |
1232 | GO:0034762 | 0.00 | 2.33 | 58.98 | 98 | 202 | regulation of transmembrane transport | ABL1, ACTN4, ARF1, FXYD2, BAX, BDKRB1, BMP4, CACNA1A, CACNA1B, CACNB1, CACNB2, CACNB4, CACNG1, CASQ1, CLCN2, CLCN3, CLCN6, CLCN7, CLCNKA, CLCNKB, CRH, CRHBP, CTSS, CYBA, DIAPH1, DNM2, DPP6, EDNRA, F2, F2R, PTK2B, GCG, HRC, IL13, INS, KCNA1, KCNA3, KCNA4, KCNA5, KCNC2, KCND2, KCND3, KCNJ1, KCNJ2, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ14, KCNJ16, KCNS1, KCNS2, KCNS3, P2RX7, PDE4B, PDPK1, FXYD3, PRKD1, PTAFR, PTPN3, PTPN6, RYR2, S100A1, SCN1A, SCN2A, SCN2B, SCN4B, SCN5A, SCN7A, SCN8A, XCL1, SLC8A1, SLC9A1, SLC34A1, SNCA, SNTA1, STC1, TRPC1, VDAC1, VDAC2, YWHAH, ZP3, KCNAB2, RIPK1, RGN, KCNAB3, NRXN1, KCNK6, AKAP7, AKAP6, ATG5, WDR1, HCN4, KCNK7, AKAP9 |
1233 | GO:0007275 | 0.00 | 2.33 | 352.59 | 553 | 1331 | multicellular organism development | ABAT, ACP2, ACTA2, ACTB, ACTG2, ACTL6A, ACTN1, ADCY1, ADCYAP1R1, ADRA1B, ADRBK1, AP2B1, AEBP1, AES, AGTR1, AHR, AK2, ALAS2, ALDH3A2, ALK, AMBN, AMELY, ANG, ANPEP, APBB2, APLP2, APRT, AQP5, AQP6, ARAF, ARCN1, ARF4, ARHGAP5, PHOX2A, STS, ARSE, ASNS, ASTN1, ATF3, RERE, ATP2B1, ATP5F1, ATP5J, ATR, AVPR2, BCHE, BCL3, BCL9, TNFRSF17, BFSP1, BMP3, BMP8B, BMX, ZFP36L2, BSG, BST2, CAPN5, DAGLA, CACNB1, CACNB2, CACNB4, CALM3, CAMK2A, CAMK2G, CAPN1, CASP5, CASP9, CASP10, CASQ1, CCNE1, CCNF, CD3D, CD4, CD8A, CD9, TNFRSF8, TNFSF8, CD72, CDH1, CDK2, CDK4, CDO1, CEBPE, CEBPG, CENPE, CHAT, CHD2, CHRM1, CHRM3, CHUK, TBCB, AP2M1, AP2S1, CLCN2, CLU, TPP1, CLN5, CMKLR1, CNP, COL4A5, COL6A2, COL6A3, COL9A1, COL9A2, COL10A1, COL15A1, COL19A1, COMP, COX6B1, COX7B, CR2, CRYAB, CRYBA1, CRYBA4, CRYGB, CSF2RB, CSNK2A1, CSNK2A2, VCAN, CSPG4, CSRP2, CTF1, CTNS, CTNND1, CTNND2, CYLC1, CYLC2, DAPK3, DAZ1, DBI, DBP, DDX1, DHFR, DHODH, DIAPH2, DLG2, DLG3, DNM1, DNASE1L2, DNMT1, ATN1, RCAN1, EPYC, DUSP7, DUSP9, E2F5, EBF1, TYMP, PHC2, EFNA3, EFNA4, EIF2B1, EIF4A1, ELAVL1, ELAVL3, ELK3, ELN, EML1, EMD, ENPEP, SLC29A1, EPHA5, EPHA8, EYA4, ERG, ETV1, ETV6, EVPL, EXTL1, EZH1, F7, FABP7, FANCF, FANCG, FAP, FBLN1, FGA, FGD1, FGF6, FGF11, FLII, FLT4, AFF2, CENPI, GAA, GABRA4, GABRA5, GABRB2, GFRA1, GHRHR, GJA4, GJB1, GLO1, GLRB, GLUD1, GNAT1, GNAT2, GNGT1, GNRH2, GNRHR, GPD2, GPI, GPLD1, GPM6A, GRIN2A, GSS, HIST1H1T, H3F3B, HAS2, HCCS, HEXB, HIC1, HIVEP2, HK2, HLF, HMBS, NR4A1, HNF4G, ONECUT1, HNMT, HPGD, HPRT1, HSF4, IAPP, IDH1, IDUA, IFI16, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGF2, IL2RB, IL2RG, IL11RA, TNFRSF9, IL18, IMPDH1, IMPDH2, INS, ITGA1, ITGA9, IVL, JARID2, JUP, KCNA1, KCNC2, KCNJ8, KCNJ10, KCNK3, KCNQ1, KIF5A, KLKB1, KRT2, KRT9, KRT13, KRT16, LIM2, LIPC, MAL, MARK3, MATN3, RAB8A, MEN1, MFGE8, MGMT, ATXN3, MKI67, DRG1, NRF1, NTN3, ODC1, ODF1, OGDH, OMP, OPHN1, CLDN11, OVOL1, OXCT1, P2RX5, PAEP, PRDX1, PAM, PCDH9, PCNA, PCOLCE, PDPK1, PENK, PEX7, PEX13, PHF2, SERPINB5, SERPINI1, PIM1, PIP4K2A, PLN, PPIB, PPP2R5D, PPP5C, PPT1, PRCP, PRKCQ, PRKG1, PRL, PRM2, PRPS2, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTPN3, PTPN14, PTPRA, PTPRJ, PTPRN, PTPRS, PURA, QARS, QDPR, RAC2, RAF1, RAG2, RASA2, PRPH2, RHAG, RPGR, RPL22, RPL24, RPS4Y1, RPS6KA1, RPS6KA2, RPS6KA3, RPS19, RPS27A, RYR1, S100A1, SORT1, S100A4, S100A7, S100A8, S100A9, SAT1, SATB1, SCN2A, SCN2B, SCN5A, SCN8A, SDHA, TRAPPC2, SRSF5, SFTPB, SGCA, SGCB, SGCD, ITSN1, SHB, SHC1, SIAH2, SLC2A2, SMTN, SLC8A3, SLC9A1, SLC12A1, SLC34A1, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCE1, SMPD1, SPG7, SPRR2A, SPRR2D, SPRR2E, SPRR2G, SPRR3, SPTA1, SPTB, SRPK2, STRN, STXBP3, TACC1, ADAM17, TAZ, CLEC3B, TNFAIP2, TNFRSF1B, TNNC1, TNNI3, TOP2B, TPD52, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TSG101, TSPY1, TUFT1, TULP1, TYR, TYRO3, UBE3A, UFD1L, SCGB1A1, UGT8, UPK2, UPK3A, VCL, WFS1, WRN, ZFX, ZNF3, ZNF7, ZNF22, ZNF24, ZNF45, ZNF74, ZNF141, ZNF148, VEZF1, ZNF217, PRDM2, PTP4A1, RNF103, SCG2, KCNAB1, MAFK, SLC7A5, MADCAM1, DPF1, NRIP1, PICALM, FZD4, FZD8, FZD9, GFI1B, BCAR3, LTBP4, NR0B2, CUL1, ATRN, SORBS2, CNTNAP1, KCNAB2, GAS7, PIR, KLF7, UNC5C, DYNLL1, PEA15, JRKL, EED, ADAM19, TNFRSF18, RGS9, TNFRSF10D, TNFRSF10B, TNFRSF10A, CREG1, IL18R1, CDKL1, SAP30, LIN7A, IQGAP1, NRP2, ARHGEF7, VNN2, EIF2B3, EIF2B2, BSN, RPS6KA4, RNF8, BAZ1B, PAPSS1, CLDN1, ATP6V0D1, SYNGR3, DYRK1B, EXO1, DCLK1, ZMYM6, BMP15, AURKB, VAPA, RPS6KA5, PDLIM7, COPS2, TRIP11, GTF3C5, NRXN2, CHST3, ATG5, ONECUT2, PSMF1, SLC4A7, ADAMTS4, BAG3, NRG2, CXCL14, MINPP1, KLK4, FEZ2, ZNF516, UTP14C, VPRBP, FAM65B, SNX17, SPOCK2, RB1CC1, SPATA2, ARHGEF11, ZBTB24, GAB2, RBX1, SLC12A6, NR2E3, RANBP9, ABCB6, PTPRU, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, FEM1B, FRY, RASA4, FARP1, WASF2, ZNF256, PSME3, DHRS2, PSMD14, PRG4 |
1234 | GO:0043410 | 0.00 | 2.33 | 21.40 | 36 | 75 | positive regulation of MAPK cascade | ADAM8, ADRA1B, ALK, CD40, CSPG4, LPAR1, EFNA1, EPHA8, FLT3, FPR1, GNG3, HGF, IGF1, IGF1R, IGF2, IGFBP3, ILK, INS, IRAK1, IRAK2, ITGA1, ITGB1, KISS1, NTRK2, NTRK3, P2RX7, PRKAA1, PRKCE, PSAP, RYK, S100A12, TNFRSF1B, TP73, IKBKG, MADD, PDE5A |
1235 | GO:0071772 | 0.00 | 2.33 | 25.17 | 42 | 86 | response to BMP | ABL1, ACVR2B, ACVRL1, XIAP, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, RUNX2, COL2A1, DLX5, ETV2, FBN1, FGF8, FOXD1, GATA3, GATA4, GATA6, GDF9, GPC3, ID1, RBPJ, ILK, KCND3, SMAD1, SMAD6, SMAD7, SMAD9, MAPK3, RYR2, SOX11, T, UBE2D1, WNT1, USP9X, USP9Y, CHRD, PHOX2B, BMP15, ZFYVE16 |
1236 | GO:0002793 | 0.00 | 2.33 | 13.75 | 23 | 47 | positive regulation of peptide secretion | ABAT, BAD, BLK, CRH, FGA, GCG, GHRHR, GLUD1, GPLD1, FFAR1, INS, ISL1, KISS1, OXCT1, PRKCE, PSMD9, S100A8, S100A9, SOX4, TRH, TRPM2, NR0B2, ARHGEF7 |
1237 | GO:0035295 | 0.00 | 2.33 | 31.68 | 53 | 110 | tube development | ACAT1, AQP1, ARG1, ARG2, ATRX, BMPR1A, BMPR2, CAT, CREB1, CRH, CTGF, CYP1A2, DHCR7, EIF4E, EN1, EP300, FGF7, HSD11B1, ID1, IL13, ING2, LIPA, LTA4H, SMAD1, SMAD6, SMAD7, SMAD9, NUMA1, MAPK1, MAPK3, PROX1, PTN, RAB3A, SDC1, SFTPD, SIM2, SLC8A1, SP1, SP3, SPARC, SREBF1, UBB, AIMP2, IFT88, CHRD, NUMB, ADAMTS2, TRAF4, PHF14, ADAMTSL2, IFT140, REC8, ATP6AP2 |
1238 | GO:0042180 | 0.00 | 2.33 | 43.31 | 72 | 148 | cellular ketone metabolic process | ACACB, ANXA1, BHMT, CBR1, AKR1C4, CNR1, COMT, CYP11B1, DLD, FSHB, GATA3, GCG, KAT2A, GHSR, GLO1, GOT2, GPI, HMGCR, HPN, HSD17B3, IDO1, INS, INSIG1, OAZ1, OAZ2, ODC1, OXCT1, PDK4, PRKAB2, PRKCE, PROX1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTGS2, REST, SNCA, SRD5A1, SREBF1, STAT5B, NR1H2, PDHX, CYP4F2, AKR1C3, KYNU, RGN, EIF2AK3, PSMF1, NR1D1, NR1H4, DHRS9, PSME3, PSMD14 |
1239 | GO:0030855 | 0.00 | 2.32 | 38.32 | 64 | 133 | epithelial cell differentiation | ACVR2B, ALDOC, ANXA4, BMPR2, CAPN5, CBR1, CD63, CDX2, TPP1, CNN3, DLX5, S1PR1, EDNRB, ELF3, EMX1, ERCC3, EVPL, FGF8, NR5A2, FZD2, NRG1, ID2, IVL, JUN, KIT, KRT2, KRT4, KRT14, KRT16, MEN1, MGMT, PCNA, PSAP, PTN, RAB27A, RXRA, S100A7, SOX4, SOX10, SOX11, SPRR2A, SPRR2D, SPRR2E, SPRR2G, SPRR3, NR2F2, TSG101, UPK1B, UPK2, UPK3A, VDAC1, VEGFA, VIL1, WNT11, MADCAM1, TAGLN2, AKR1C3, SCEL, NRP1, LATS1, CBFA2T2, KLF4, PTER, DHRS9 |
1240 | GO:0050896 | 0.00 | 2.32 | 35.10 | 62 | 162 | response to stimulus | ABCA2, ABCA3, ACP2, ADD3, AK2, AMPD1, ANXA11, ATP12A, ATP4A, ATP5G3, CA6, ENTPD6, CNGA2, CPOX, CRX, CST1, CYB5A, CYC1, TRDMT1, EMX1, EMX2, GAD1, GOT2, GYS2, HADHA, HPRT1, INPPL1, LCAT, MFGE8, PFAS, ABCB1, PPP2R2A, PPT1, ABCD3, RBBP4, RNF2, S100P, SCN2B, SCN8A, SCNN1A, SCNN1G, SEPW1, SLC2A2, SLC9A3, SLC22A1, SLC22A2, SLC22A5, SQLE, SRP14, TBCE, TOP1, UQCRFS1, CLRN1, SLC30A2, PRDM2, SLC10A3, SLC25A12, SLC22A8, RNF40, EPM2AIP1, SLC25A13, IRX5 |
1241 | GO:0009887 | 0.00 | 2.32 | 32.23 | 54 | 113 | organ morphogenesis | AES, ARG1, BMP1, CAPN1, CD44, CDX2, CRKL, CRX, CSF1R, CTGF, DCN, E2F5, EFNB2, ELF3, ELN, EMX1, EP300, FGD1, FGF6, FOXD1, NR5A2, GPC3, HCCS, HOXD8, IDUA, IGF1R, IGF2, MKI67, NTF4, P2RX7, PAX3, PGR, SERPINB5, PRKX, PSPN, PTEN, RFNG, RPS6KA1, SFTPB, SLC6A4, SLC12A2, SMARCC1, SNAI1, SOX3, STAT6, SYK, TRPS1, CUL3, CUL1, SGPL1, SLIT2, ONECUT2, IFT140, FEM1B |
1242 | GO:0051240 | 0.00 | 2.32 | 181.92 | 295 | 629 | positive regulation of multicellular organismal process | ABAT, ABL1, ABL2, ACACB, ACVR1B, ACVR2B, ADA, ADRA1B, AGTR2, ALB, ALOX15B, BIN1, ANGPT1, ANXA1, APBB1, BIRC3, APOH, ARF1, ARNT, ARNTL, ASCL1, ATF4, ATP1A1, ATP2A1, AVPR1B, AVPR2, AXL, BAD, ADGRB2, BBS4, BCL3, PRDM1, BMPR1A, BTK, TSPO, CASP5, CASP8, CBLB, CCNB1, CD3E, CD4, CD6, CD14, CD28, CD86, TNFRSF8, CD36, SCARB1, CD40, CD58, CD74, CDC20, CEBPG, CHRM3, CHUK, CLU, CCR1, CNR1, COL1A1, CPS1, CREB1, CRH, CRX, CSF1R, CSF2, CYBA, CYP27B1, BRINP1, DBH, DCT, DDX3X, DLX5, DNMT3B, DPYSL3, DRD3, LPAR1, EDNRA, EDNRB, EFNA5, EFNB2, EGR3, CTTN, EP300, EPHA3, EPHA4, EPHB1, EPHB2, EPHB3, EPOR, ETV5, F7, F12, FCER1A, FGA, FGF3, FGF7, FGF8, FGR, FOXD1, FLT3LG, FLT4, FYN, GALR1, GATA3, GDNF, GFAP, GHRHR, GHSR, GNAS, GOLGA4, GPC1, GPLD1, GPM6B, FFAR3, RAPGEF1, HAS2, HCLS1, HMGCR, FOXA2, HOXC11, HPN, HRH1, HRC, PRMT1, ICAM1, ID2, IFI16, IFNG, IGF1, IGF2, RBPJ, IL2RA, IL3, IL10, IL12RB2, IL13, ILK, IDO1, INHA, INS, IRAK1, IRF1, IRF5, ITGB1, JUN, JUND, KCNQ1, KISS1, KIT, KNG1, LIMK1, LTF, CAPRIN1, MAP1B, KITLG, NRCAM, NTRK2, NTRK3, DDR2, OPA1, OTX2, OXTR, P2RX7, P2RY2, PAEP, PALM, PAX2, PCP4, PDE4B, SERPINF1, PENK, PPIB, PRG2, PRKAA1, PRKCE, PRKCI, PRKCQ, PROX1, PTCH1, PTH, PTGS1, PTN, PTPRZ1, RAG1, RAG2, RARA, RARB, RB1, RET, RFX3, RHEB, RPS6KB1, RPS19, RPS27A, RYR2, S100A9, SALL1, XCL1, SEC14L1, SELP, SGK1, SHC1, SLC8A1, SLC9A1, SLC22A5, SMARCD3, SNAI1, SOX10, SOX11, SPARC, SRF, SRY, TRIM21, STAT5B, STAT6, SYT1, SYT4, TACR2, ADAM17, TACR3, TAL1, KLF10, TP73, TPBG, NR2C2, TRAF2, TRPC3, TNFSF4, UBB, UNG, NR1H2, USF1, VIL1, VIP, TRPV1, WNT1, WNT11, XRCC2, XRCC5, ZNF16, RNF112, ZP3, LRP8, FZD5, FZD3, RND2, SF3A2, OGT, SEMA7A, IKBKG, AP3B1, TP63, PTCH2, NUMB, PDE5A, VAMP8, TRADD, RIPK1, TNFSF13, TNFSF9, RIPK2, IL1RL2, IL18R1, NRP2, NRP1, VNN1, PHOX2B, AP3D1, USP2, CBFA2T2, IL1RL1, ARHGEF2, PDLIM7, ITGB1BP1, SLIT2, KL, NRXN3, NRXN1, LIPG, GSTO1, EIF2AK3, IL27RA, AKAP6, ATG5, BCAR1, PPM1F, PUM1, RIMS2, CUL7, ZEB2, RBM19, HDAC6, ATP6AP2, OLIG2, SPRY1 |
1243 | GO:0009168 | 0.01 | 2.32 | 12.57 | 21 | 43 | purine ribonucleoside monophosphate biosynthetic process | ADA, ADSS, AK1, AK2, AMPD1, AMPD2, APRT, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V0A1, LDHC, PFAS, PRPS2, STAT3, SLC25A13 |
1244 | GO:0072599 | 0.00 | 2.31 | 22.83 | 38 | 78 | establishment of protein localization to endoplasmic reticulum | FAU, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, RYR2, SRP9, SRP14, SSR3, RPL14, RPL23, SPCS2 |
1245 | GO:0006952 | 0.00 | 2.31 | 20.63 | 35 | 76 | defense response | ANXA3, KLK3, BCL3, BNIP3L, BPI, CAMLG, CD8A, TNFSF8, CD74, CEBPE, CTSG, CXADR, DBI, DPP4, EIF4E, HRG, HTR2C, IFNW1, KCNJ8, KCNN4, P2RY11, PRG2, DNAJC3, PSG3, RAB1A, RNASE6, RPS6KB1, ADAM17, NR2E1, TPSAB1, VDAC1, SOCS6, IL27RA, ADAMTS4, ABCC9 |
1246 | GO:0042475 | 0.01 | 2.31 | 12.00 | 20 | 41 | odontogenesis of dentin-containing tooth | ACVR2B, AMBN, BAX, BMP4, BMPR1A, BSG, RUNX2, CHUK, CTNNA1, EDA, FGF4, FGF8, ITGA6, SCN5A, SLC34A1, IFT88, TP63, HAND1, KLK4, BCL2L11 |
1247 | GO:0045087 | 0.00 | 2.31 | 100.19 | 165 | 350 | innate immune response | ABL1, ABL2, ACTB, ADCY1, ADCY7, ADRBK1, ANG, ANGPT1, ANXA1, APP, ARAF, ART1, ASS1, AXL, BAD, BCL2L1, BLK, BMX, C3, C7, CAMK2A, CAMK2G, CASP9, CASP10, CD3G, CD4, CD6, CD28, CD44, CD58, CD59, CDKN1A, CEBPG, CLU, CR2, CSF1R, CSF2, CSF2RB, CYP27B1, CD55, DAPK3, DDX3X, DUSP5, DUSP9, EPRS, F12, PTK2B, FAU, FCER1A, FCGR2A, FCN2, FGA, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FGR, GAPDH, GATA3, GRB2, GRIN2A, NRG1, NR4A1, ICAM1, IFNG, IFNGR1, IL1RAP, IL2RA, IL2RB, IL2RG, IL3, KIT, KRT16, LIMK1, MARK3, KITLG, CIITA, FOXO4, P2RX7, PRDX1, PCBP2, CFP, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKD1, PRKCQ, PRKCSH, PROS1, PTAFR, PTEN, PTK2, PTPRA, RAB27A, RAC1, RASA2, RNASE3, RPL39, RPS6KB2, S100A7, S100A8, S100A9, S100A12, CCL21, CCL22, CCL25, XCL1, CX3CL1, SFTPD, SHC1, SLAMF1, SLPI, SNCA, SPTA1, SPTB, SRPK2, TRIM21, STAT6, XCL2, TRAF2, TYROBP, UBA7, SUMO1, VIP, VTN, WAS, LAT2, XRCC5, TRIM25, FGF23, HIST1H2BF, HIST2H2BE, CUL3, FCN3, STX11, PEA15, ADAM15, IL1RL2, CD84, VNN1, TAX1BP1, KYNU, PSTPIP1, ARHGEF2, KL, GRAP2, ATG5, NRG2, RAPGEF2, GAB2, RBX1, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, AKAP9, TRIM28, RASA4, WASF2 |
1248 | GO:0016525 | 0.01 | 2.31 | 11.41 | 19 | 39 | negative regulation of angiogenesis | ANGPT2, APOH, KLK3, ADGRB2, KRIT1, COL4A3, CX3CR1, DCN, GTF2I, HHEX, HRG, FOXO4, SERPINE1, SERPINF1, PTN, SPARC, ITGB1BP1, KLF4, SEMA3E |
1249 | GO:0033048 | 0.01 | 2.31 | 11.41 | 19 | 39 | negative regulation of mitotic sister chromatid segregation | ATRX, BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DUSP1, MAD2L1, TTK, UBE2D1, ZNF207, TNKS, CDC23, CDC16, ZW10, BUB3 |
1250 | GO:0051985 | 0.01 | 2.31 | 11.41 | 19 | 39 | negative regulation of chromosome segregation | ATRX, BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DUSP1, MAD2L1, TTK, UBE2D1, ZNF207, TNKS, CDC23, CDC16, ZW10, BUB3 |
1251 | GO:0006140 | 0.00 | 2.30 | 30.14 | 50 | 103 | regulation of nucleotide metabolic process | ABCA1, ADCY7, ADCYAP1R1, ARNT, AVPR2, BPGM, TSPO, CALM3, CDA, CRH, DRD3, DRD5, LPAR1, EDNRA, EDNRB, PTK2B, FSHR, FZD2, GALR1, GCG, GHRHR, GNAI3, GNAS, GUCA1A, GUCA2A, GUCA2B, IGF1, INS, NTRK2, P2RX7, P2RY11, PALM, PGAM1, PRKAA1, PRKAG1, PTH, RAF1, RCVRN, SNCA, STAT3, VEGFA, VIP, VIPR2, WFS1, OGT, PDE5A, AKAP6, GABBR2, AKAP12, GUCA1C |
1252 | GO:0048568 | 0.00 | 2.30 | 16.20 | 27 | 56 | embryonic organ development | ARNT, ASCL2, PRDM1, BMPR1A, CASP8, CDX2, CSF2, ERCC3, GRB2, HHEX, RBPJ, IL10, ITGA4, JUNB, LLGL2, PTCH1, RAD23B, RARA, RBBP6, SLC8A1, SNAI1, SP2, ST14, NR2F2, EOMES, SOCS3, TRIM28 |
1253 | GO:0018107 | 0.01 | 2.30 | 10.83 | 18 | 37 | peptidyl-threonine phosphorylation | ACVR1B, ADRBK1, CALM3, CDK5, CHEK1, CLK1, GCG, UBE2K, SMAD7, PDPK1, PRKCB, MAPK1, VRK1, OGT, TNKS, RIPK2, VPRBP, OXSR1 |
1254 | GO:0051899 | 0.01 | 2.30 | 10.22 | 17 | 35 | membrane depolarization | ABL1, ATP1A2, CACNA1A, CACNA1B, CACNB4, CHRNB2, JUN, KCNH2, KCNJ2, P2RX4, SCN1A, SCN2A, SCN4B, SCN7A, SCN8A, SLC8A1, YWHAH |
1255 | GO:0007596 | 0.00 | 2.30 | 48.87 | 81 | 170 | blood coagulation | ABL1, ANGPT1, ANGPT2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, BSG, C3, CD44, CD58, CD59, CD74, CDK2, CDK5, CENPE, CXADR, F10, FBLN1, FGR, GATA3, GATA4, GATA6, GRB7, H3F3B, HBD, HBE1, FOXA2, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, ITGA6, IRF1, ITGA1, ITGA2, ITGA4, ITGA5, ITGAL, ITGAM, ITGAV, ITGB1, KIF5A, OLR1, SERPINA5, PRCP, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, RAB5A, RAB27A, RAD51C, RAD51B, SELE, SELL, SELPLG, SLC8A1, SLC8A3, WAS, LRP8, MAFK, SLC7A5, AKAP1, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, CYP4F2, AP3B1, PDE5A, CD84, PROZ, HIST1H3F, DOK2, KIF3B, MFN2, KCNMB2 |
1256 | GO:0010951 | 0.00 | 2.30 | 43.61 | 72 | 149 | negative regulation of endopeptidase activity | BIRC3, XIAP, BIRC5, APLP2, APP, AQP1, BST2, C3, CASP8, CD44, CDKN2D, COL4A3, COL6A3, CR1, CRYAB, CSNK2A1, CST1, CST6, DDX3X, DPEP1, SERPINB1, IFI6, GPI, GPX1, HGF, HRG, IFI16, ITIH1, ITIH2, ITIH4, KNG1, SERPINE1, PAX2, SERPINA5, SERPINF1, SERPINA4, SERPINB5, SERPINB6, SERPINB9, SERPINI1, SERPINB13, SERPINI2, PROS1, PZP, RAF1, RAG1, RENBP, RPS6KA1, RPS6KA3, SERPINB4, SIAH2, SLPI, SNCA, SORL1, SPINK1, SPOCK1, SERPINA7, TRAF2, VEGFA, VIL1, VTN, PICALM, SERPINB7, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, USP14, KLF4, PSMF1 |
1257 | GO:0030335 | 0.00 | 2.29 | 42.28 | 70 | 146 | positive regulation of cell migration | ACTN4, ACVR1B, ANGPT1, ANXA3, AQP1, ARHGAP5, BMP4, BMPR2, SCARB1, COL1A1, CSF1R, CTSH, DAPK3, DIAPH1, S1PR1, ETS1, F2R, F10, FBLN1, FGF7, FGR, FLT1, FLT4, FSHB, GATA3, GPLD1, GRB7, HGF, ONECUT1, HSPB1, IFNG, IGF1R, ILK, INS, ITGA5, ITGAV, ITGB1, JUN, KDR, KIT, SMAD3, NTRK3, PRKD1, MAPK1, PROX1, PTGS2, PTK2, PTPRZ1, RET, SEMA3F, SNAI1, SOX9, SPARC, TRIP6, VIL1, WNT11, PTP4A1, SEMA3B, SEMA7A, IKBKAP, NUMB, NRP2, ITGB1BP1, ONECUT2, BCAR1, PPM1F, RAPGEF2, SEMA3E, HDAC6, PDCD6 |
1258 | GO:0006006 | 0.00 | 2.29 | 17.46 | 29 | 60 | glucose metabolic process | ACACB, BAD, CACNA1A, CALM3, GAA, GCGR, GYS2, HK2, FOXA2, ONECUT1, IGFBP3, INPPL1, KCNJ11, OAS1, PDK4, PFKFB4, PHKA2, PHKB, PHKG1, PPP1CA, PPP1R3C, PPP2R5D, PRKAA1, PYGB, PYGM, RPS27A, SORD, UBB, USF1 |
1259 | GO:0043086 | 0.00 | 2.29 | 17.97 | 30 | 63 | negative regulation of catalytic activity | ACACB, ANXA3, ANXA4, ANXA5, CNR1, CYP27B1, DRD3, DRD5, EDNRB, ENSA, GALR1, GNAI3, HP, IL13, INS, PPP1R12A, OAZ1, OAZ2, PALM, PPP1R8, PTN, SET, SNCB, SCGB1A1, CABP1, APBA3, GABBR2, PHACTR2, HDAC6, FRY |
1260 | GO:0006921 | 0.01 | 2.29 | 10.24 | 17 | 35 | cellular component disassembly involved in execution phase of apoptosis | ADD1, APAF1, BAX, BMX, CASP8, CDH1, DFFA, DFFB, DNASE1L3, FNTA, GAS2, KPNA1, PRKCQ, PTK2, SATB1, TOP2A, VIM |
1261 | GO:0051781 | 0.00 | 2.29 | 19.32 | 32 | 66 | positive regulation of cell division | BIRC5, CAT, CD28, CDC6, DRD3, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, OPN1MW, IGF1, IGF1R, IGF2, IL1A, INS, YBX1, PRKCE, PTEN, PTN, RB1, OPN1LW, TAL1, VEGFA, VEGFB, ZNF16, CUL3, AURKB, ITGB1BP1, KIF3B, DLGAP5 |
1262 | GO:0048565 | 0.02 | 2.29 | 9.03 | 15 | 31 | digestive tract development | ASCL1, PRDM1, KLF5, CCNB1, CDKN1A, CDX2, GATA3, GATA6, ITGA6, KIT, OXTR, RB1, TRPS1, TYMS, NR1H4 |
1263 | GO:0044772 | 0.00 | 2.29 | 13.20 | 22 | 46 | mitotic cell cycle phase transition | BUB1, BUB1B, CDC20, CDC27, CENPE, CSNK2A1, CSNK2A2, DDB1, DUSP1, ERCC3, MAD2L1, RPL24, TTK, UBE2D1, ZNF207, CDC23, CDC16, CTDP1, ZW10, BUB3, MAD2L1BP, KNTC1 |
1264 | GO:0007160 | 0.00 | 2.29 | 25.37 | 42 | 87 | cell-matrix adhesion | ACTN1, ACVRL1, ARHGAP6, CD44, CD63, CDK5, CTGF, DAPK3, EDA, EFNA5, CTTN, EPHA3, FGA, GPM6B, ONECUT1, ITGA6, ITGA1, ITGA2, ITGA4, ITGA7, ITGAL, ITGAV, ITGB1, ITGB5, SERPINE1, PDPK1, PTEN, PTK2, SLC9A1, SIGLEC1, SRF, CNTN2, TRIP6, VCL, VTN, MADCAM1, ADAM15, ARHGEF7, ONECUT2, SEMA3E, SLK, BCL2L11 |
1265 | GO:1902531 | 0.00 | 2.29 | 123.40 | 201 | 430 | regulation of intracellular signal transduction | ACTN4, ADA, ADAM8, ADRA1B, ALK, ANGPT1, BIRC3, XIAP, ARAF, ATP6AP1, ATR, AXL, BAD, BAX, BCL3, BMP1, BMP3, BMP8B, BST2, BUB1, C3, CAMK2A, CAMK2G, CASP10, CAT, CBL, CD3E, CD4, CD8A, CD28, CD36, CHUK, CCR1, CMKLR1, CRKL, CSF2RB, CSPG4, CTH, DDX5, RCAN1, ECM1, EDA, EDNRA, EFNA1, EPHA8, EPOR, F2, F3, F7, F10, FGA, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGR, FLT1, FPR1, FSHR, GATA3, GDF9, GNAI1, GNAS, GNG3, GRB2, GRIN2A, GRM1, HIC1, HRC, HTR2C, ICAM1, ID1, IGF2, IGFBP3, IL2RA, IL2RB, IL2RG, ILK, INHA, IRAK1, IRAK2, ITGA1, ITGAL, JUN, KDR, KISS1, LTF, MARK3, NTRK2, NTRK3, P2RX3, P2RX4, P2RX5, PDPK1, PLN, PPP5C, PRKCB, PRKCE, PRKD1, PRKCQ, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTGS2, PTK2, PTPRA, RAP1A, RHEB, RPS27A, RRAS, RYK, S100A4, S100A7, S100A8, S100A9, S100A12, S100A13, CCL22, CCL25, XCL1, CX3CL1, SELP, SFPQ, SHC1, SLC9A1, SLC12A1, SLC20A1, SOX9, SOX11, SPTA1, SPTB, STYX, XCL2, TNFRSF1B, TSG101, UBB, UBE2V1, UBE3A, VEGFB, WNT11, TRIM25, ZP3, FGF23, SEMA7A, IKBKG, PRKRA, AKR1C3, PDE5A, PEA15, TRADD, TNFSF10, TNFRSF10B, TNFRSF10A, IL18R1, INPP4B, NRP1, AKAP4, RGN, BMP15, VAPA, KL, EIF2AK3, AKAP6, PSMF1, GDF15, BAG4, NRG2, AKAP12, RAPGEF2, PUM1, TNFSF15, RBX1, BCL2L11, AKAP9, ATP6AP2, RNF41, PSME3, PSMD14, RCAN2 |
1266 | GO:0009408 | 0.00 | 2.28 | 26.05 | 43 | 89 | response to heat | ATR, CAMK2A, CAMK2G, CASQ1, CD14, CDKN1A, CRYAB, DNMT1, EIF2B1, EP300, HSBP1, HSPA6, HSPB2, IGF1, IL1A, IL1R1, IRAK1, ATXN3, MKI67, NUP98, P2RX3, PRKCQ, MAPK1, MAPK3, RANBP2, RPA2, RPA3, RPS6KB1, DNAJC7, TRPV1, NUP214, AAAS, EIF2B3, EIF2B2, SOCS3, BAG5, BAG4, BAG3, BAG2, NUP155, NUP93, HDAC6, PDCD6 |
1267 | GO:0031401 | 0.00 | 2.28 | 200.18 | 320 | 684 | positive regulation of protein modification process | ABL1, ABL2, ACVR1B, ACVR2B, ACVRL1, ADAM8, ADCY1, ADCY7, ADRA1B, AGTR2, ALK, ANG, ANGPT1, BIRC3, XIAP, ARAF, ARNT, ATP6AP1, AVPR2, BAX, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, C3, CALM3, CAMK2A, CAMK2G, CAV3, CCNB1, CCNC, CCNT2, CD3E, CD4, CD36, CD40, CD44, CD74, CDC6, CDC20, CDC27, CDK5, CDKN1A, CENPE, CLU, CCR1, CRH, CRKL, CSF1R, CSF2, CSF2RB, CSNK1D, CSPG4, CTF1, CTGF, ACE, DNMT1, DNMT3B, DUSP5, DUSP7, DUSP9, LPAR1, EDNRA, EDNRB, EFNA1, EFNA5, EMP2, EPHA4, EPHA8, EPOR, ERCC6, F2, F2R, PTK2B, FCER1A, FGA, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FLT1, FLT3, FLT3LG, FLT4, FNTA, FPR1, FSHR, FYN, GCG, KAT2A, GDF9, GNG3, GOLGA2, GPLD1, GRB2, RAPGEF1, GRIN2A, GRM1, HIST1H1B, HCLS1, HGF, NRG1, UBE2K, HMGCR, HPX, PRMT1, DNAJB2, HTR2C, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF1R, IGF2, IGFBP3, IL1A, IL2RA, IL2RB, IL2RG, IL3, IL12B, IL13, IL18, ILK, INHA, INS, IRAK1, IRAK2, ISL1, ITGA1, ITGA2, ITGA5, ITGB1, JARID2, JUN, KDR, KISS1, KIT, LTF, SMAD3, SMAD7, MARK3, KITLG, MAP3K11, PPP1R12A, NTRK2, NTRK3, DDR2, P2RX7, PDPK1, PFN2, PHB, PIM1, PPP1R7, PPP5C, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRKD1, MAPK1, MAPK3, PROX1, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, PTPRA, PTPRZ1, RAC1, RAF1, RAP1A, RAP2A, RAP2B, RASA2, RET, RPS3, RPS27A, RYK, S100A7, S100A12, CCL21, CCL22, CCL25, XCL1, CX3CL1, SDC4, SHC1, STIL, SKP1, SKP2, SLAMF1, SMPD1, SUMO3, SNCA, SOX4, SOX9, SPTA1, SPTB, SREBF1, STK10, XCL2, SYK, ADAM17, TNFRSF1A, TNFRSF1B, TP73, TPD52L1, TRAF2, TTK, UBB, UBE2D1, UBE2L3, UBE3A, VEGFA, VEGFB, VTN, WFS1, WNT1, WNT11, ZP3, LRP8, FZD5, AIMP2, ARHGEF5, FGF23, CDK2AP1, FZD4, FZD7, FZD8, BCAR3, CUL3, CUL1, OGT, SEMA7A, IKBKG, CDC14B, MADD, PDE5A, PEA15, CDC23, EED, RIPK1, RIPK2, TNFRSF18, TNFRSF10B, TNFRSF10A, IQGAP1, NRP1, CDC16, RPS6KA4, TNFSF18, UNC119, RGN, LATS1, ARHGEF2, BMP15, VAPB, RPS6KA5, ITGB1BP1, GPR55, KL, AKAP6, PSMF1, GDF15, BAG4, NRG2, TRAF4, RAPGEF2, SLK, RASSF2, ATG13, RNF40, RB1CC1, ZEB2, OXSR1, TNFSF15, RBX1, RAD50, AKAP9, RASA4, PSME3, PSMD14 |
1268 | GO:0040017 | 0.00 | 2.28 | 51.68 | 85 | 178 | positive regulation of locomotion | ACTN4, ACVR1B, ADAM8, ANGPT1, ANXA3, AQP1, ARHGAP5, BDKRB1, BMP4, SCARB1, COL1A1, CSF1R, CTSH, DAPK3, DIAPH1, ETS1, F2R, F10, FBLN1, FGF7, FGR, FLT1, FLT4, FSHB, GATA3, GPLD1, GRB7, HAS2, HGF, ONECUT1, ICAM1, IFNG, IGF1, IGF1R, ILK, INS, ITGA4, ITGA5, ITGAV, ITGB1, JUN, KIT, KITLG, DDR2, P2RY2, P2RY6, PRKCE, MAPK1, PROX1, PTAFR, PTGS2, PTK2, PTPRZ1, RET, RPS6KB1, SELE, SELP, SEMA3F, SLC8A1, SNAI1, SOX9, SPARC, TRIM21, TRIP6, VIL1, VTN, WNT11, ZP3, PTP4A1, SEMA3B, MADCAM1, SEMA7A, IKBKAP, NUMB, TNFRSF18, NRP2, ARHGEF7, ITGB1BP1, ONECUT2, BAG4, BCAR1, RAPGEF2, SEMA3E, HDAC6, PDCD6 |
1269 | GO:0051640 | 0.03 | 2.28 | 7.23 | 12 | 25 | organelle localization | BICD1, CAV3, HHEX, NUBP1, PCM1, PEX1, PEX13, PTEN, RAB6A, TACC1, UVRAG, NRXN1 |
1270 | GO:0001756 | 0.02 | 2.27 | 9.07 | 15 | 31 | somitogenesis | BMPR1A, CDX2, EP300, KAT2A, FOXA2, SMAD3, MEOX2, OTX2, PAX3, PCDH8, T, KDM6A, XRCC2, RGS20, ZEB2 |
1271 | GO:1903793 | 0.02 | 2.27 | 9.07 | 15 | 31 | positive regulation of anion transport | ABAT, CHRNB2, GDNF, NTSR1, P2RX4, P2RX7, P2RY2, PCP4, PTAFR, RAB3B, SLC34A1, TACR2, TRH, CYP4F2, VAMP8 |
1272 | GO:0046661 | 0.00 | 2.27 | 24.88 | 41 | 85 | male sex differentiation | NR0B1, ATRX, BAX, BCL2L1, BIK, BMPR1A, BOK, COL9A3, CTNNA1, FGF8, FGF9, FSHB, FSHR, GATA3, GATA4, GATA6, GJB2, HSD17B3, HSD17B4, ICAM1, ING2, INHA, KIT, KITLG, PRKACG, RARA, RRM1, SDC1, SOX9, SRD5A1, SRY, STAT5B, UBB, UTF1, AKR1C3, ADAM15, SGPL1, EIF2S2, REC8, BCL2L11, AKAP9 |
1273 | GO:0002027 | 0.02 | 2.27 | 8.47 | 14 | 29 | regulation of heart rate | ADA, ADRA1B, AGTR2, CALM3, CASQ2, CAV3, HRC, PLN, RYR2, SLC8A1, SNTA1, SREBF1, TACR3, IRX5 |
1274 | GO:0042632 | 0.02 | 2.26 | 8.49 | 14 | 29 | cholesterol homeostasis | ABCA1, ABCA2, ACOX1, CAV3, SCARB1, NR5A2, G6PC, HPN, LCAT, LIPC, ACSM3, NR1H2, LIPG, NR1D1 |
1275 | GO:0071695 | 0.02 | 2.26 | 8.49 | 14 | 29 | anatomical structure maturation | ACVRL1, ARCN1, RERE, CACNA1A, S1PR1, FGFR3, GATA3, IGF1, RBPJ, LTF, PAX2, RET, RYR1, WNT1 |
1276 | GO:0031326 | 0.00 | 2.26 | 22.15 | 37 | 81 | regulation of cellular biosynthetic process | ABCA1, ACTN4, ACTN1, ADCY7, ANXA1, ASIP, AVPR2, C3, CALM3, SCARB1, CRH, DLD, DRD5, DTX1, FSHR, GHRHR, GNAS, GPLD1, GUCA1A, GUCA2A, GUCA2B, HPN, HTR2C, IDH1, NTRK2, P2RY11, PDK4, PRKAB2, PTPN2, RCVRN, VIP, VIPR2, PDHX, NSMAF, TRIP11, AKAP12, GUCA1C |
1277 | GO:0055065 | 0.00 | 2.26 | 78.54 | 128 | 270 | metal ion homeostasis | ABCB7, ABL1, ABL2, ADCYAP1R1, ADRA1B, ALAS2, ANXA6, XIAP, APLP2, APP, ARF1, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, AVPR1B, BAX, BDKRB1, BMP4, CACNA1A, CACNB4, CALM3, CASQ1, CASQ2, CAV3, CD4, CD36, CD40, CD52, CCR1, CCR3, CCR8, CYBA, CYP27B1, CD55, DIAPH1, DRD5, S1PR1, LPAR1, EDNRA, EPOR, F2, F2R, PTK2B, FTL, GALR1, GNA15, GNAT2, GNG3, XCR1, GRINA, GRM1, GTF2I, HEXB, HPX, HRC, HTR2C, IL13, IREB2, ITGB1, ITPR1, ITPR3, KCNA1, KCNK3, KDR, KISS1, LTF, NUBP1, NTSR1, OXTR, P2RX3, P2RX4, P2RX5, P2RX7, P2RY2, P2RY4, PDPK1, PLN, PRKCB, PRKCE, PRKD1, PTH, PTPN6, PYGM, RHAG, RYR1, RYR2, S100A8, S100A9, SCO1, CCL21, XCL1, SLC8A3, SNCA, STC1, TNNI3, TPT1, HSP90B1, TRPC1, TRPC3, TRPC4, TRPC5, TRPM2, VDR, TRPV1, WFS1, SLC30A1, SLC30A2, PICALM, S1PR4, INPP4B, AP3D1, ATP6V0E1, RGN, ATP6V0D1, VAPB, KL, GSTO1, AKAP6, ATG5, ATP6V1G1, ATP2C2, ABCB6 |
1278 | GO:0072522 | 0.00 | 2.26 | 42.14 | 69 | 144 | purine-containing compound biosynthetic process | ABCA1, ACACB, ADA, ADCY1, ADCY7, ADCYAP1R1, ADSS, AK1, AK2, AMPD1, AMPD2, APRT, AQP1, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V0A1, AVPR2, CALM3, CRH, DRD3, DRD5, LPAR1, EDNRA, EDNRB, PTK2B, FSHR, GALR1, GCG, GHRHR, GNAI3, GNAS, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GUK1, GUCY2D, HPRT1, HTR2C, IMPDH1, IMPDH2, LDHC, NTRK2, OAS1, P2RY11, PALM, PFAS, PRPS2, PTH, RAF1, RCVRN, SHMT1, STAT3, VIP, VIPR2, WFS1, PAPSS1, AKAP6, GABBR2, AKAP12, GUCA1C, SLC25A13 |
1279 | GO:1902600 | 0.00 | 2.25 | 22.53 | 37 | 77 | hydrogen ion transmembrane transport | ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP4A, ATP4B, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, COX6A1, COX6B1, COX7A1, COX7B, COX7C, COX8A, COX15, CYB5A, SLC9A1, SLC9A2, SLC9A3, UQCRC1, UQCRFS1, UQCRH, ATP6V0E1, ATP6V0D1, COX5A, ATP6V1G1 |
1280 | GO:0008285 | 0.00 | 2.25 | 66.22 | 108 | 228 | negative regulation of cell proliferation | AGTR2, ALOX15B, BAX, BCHE, BMPR2, CD9, TNFRSF8, CD37, CDC6, CDKN1A, CDKN2D, COL4A3, CSF1R, CTNNA1, CXADR, CYP27B1, DLG3, EMD, ETS1, ETV3, F2R, FABP7, PTK2B, FAP, FBLN1, FGFR3, FLT3, GAS8, B4GALT1, GPLD1, RAPGEF1, HMGA1, HRG, ID2, IFIT3, IGF1, IGFBP6, RBPJ, IL1A, TNFRSF9, ING1, ING2, INPPL1, IRF1, ITGA1, ITGB1, JARID2, JUN, KCNK2, KISS1, SMAD1, SMAD3, SMAD6, FOXO4, OVOL1, PHB, PROX1, PTGS2, PTPN2, PTPN14, PTPRJ, PTPRZ1, RAF1, RARA, RARB, RBBP4, REST, RPS6KA2, RXRA, S100A11, SFRP5, SLC6A4, SMARCA2, SOD2, SOX4, SRF, STAT3, STRN, KLF10, NR2E1, TP73, TSC1, TSG101, WNT11, FZD5, AIMP2, FOSL1, BAP1, CUL4A, CUL2, CUL1, KLF11, PPM1D, PRKRA, PHOX2B, IL1RL1, ITGB1BP1, SLIT2, SLC9A3R1, PHF14, RAPGEF2, DLEC1, FGFBP1, NR2E3, PTPRU, RNF41, DHRS2, SPRY1 |
1281 | GO:0002293 | 0.03 | 2.25 | 7.90 | 13 | 27 | alpha-beta T cell differentiation involved in immune response | ANXA1, BCL3, CD86, GATA3, IFNG, IL12B, RARA, STAT6, TNFSF4, EOMES, RIPK2, IL18R1, TNFSF18 |
1282 | GO:0006778 | 0.03 | 2.25 | 7.90 | 13 | 27 | porphyrin-containing compound metabolic process | ALAD, ALAS2, BLVRA, TSPO, COX15, CPOX, CYP1A2, HMBS, HPX, SPTA1, SPTB, UROS, ABCB6 |
1283 | GO:0019731 | 0.03 | 2.25 | 7.90 | 13 | 27 | antibacterial humoral response | ANG, APP, KLK3, DMBT1, FAU, FGA, LTF, RNASE3, RPL39, SLPI, VIP, HIST1H2BF, HIST2H2BE |
1284 | GO:0051851 | 0.03 | 2.25 | 7.90 | 13 | 27 | modification by host of symbiont morphology or physiology | AQP1, CTSG, EP300, HPN, JUN, LTF, PPIB, REST, SMARCA4, SP1, VAPB, VAPA, RAB9A |
1285 | GO:0060415 | 0.03 | 2.25 | 7.90 | 13 | 27 | muscle tissue morphogenesis | COL11A1, S1PR1, FZD2, NRG1, RBPJ, ISL1, SMAD7, PROX1, RXRA, RYR2, TNNC1, TNNI3, HAND1 |
1286 | GO:2001236 | 0.04 | 2.25 | 6.67 | 11 | 23 | regulation of extrinsic apoptotic signaling pathway | AGTR2, BAX, DAPK3, DBH, PPP1CA, PPP2R1A, PPP2R1B, RET, SIGLEC1, TRAF1, TNFSF12 |
1287 | GO:0048871 | 0.01 | 2.24 | 12.15 | 20 | 42 | multicellular organismal homeostasis | ADCY1, ADCY7, AQP1, AVPR2, HAS2, KRT16, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, RHAG, SCNN1A, SCNN1B, SCNN1G, WFS1, CYP4F2, TP63, CLDN1 |
1288 | GO:0002286 | 0.00 | 2.24 | 14.63 | 24 | 50 | T cell activation involved in immune response | ANXA1, BCL3, CD86, GATA3, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IL12B, ITGAL, RAB27A, RARA, STAT6, TSC1, TNFSF4, EOMES, STX11, RIPK2, IL18R1, TNFSF18 |
1289 | GO:0071804 | 0.00 | 2.24 | 33.66 | 55 | 115 | cellular potassium ion transport | AQP1, ATP1A1, ATP1A2, ATP1A3, ATP12A, FXYD2, ATP4A, CASQ2, CAV3, CNGA1, CNGA2, DNM2, DPP6, HPN, KCNA1, KCNA3, KCNA4, KCNA5, KCNC2, KCND2, KCND3, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN4, KCNQ1, KCNS1, KCNS2, KCNS3, REST, SUMO1, KCNAB1, KCNAB2, KCNAB3, KCNK6, AKAP7, AKAP6, OXSR1, SLC12A6, HCN4, ABCC9, KCNK7, AKAP9, KCNMB2 |
1290 | GO:0045620 | 0.04 | 2.24 | 7.31 | 12 | 25 | negative regulation of lymphocyte differentiation | ANXA1, BMP4, CD74, CTLA4, DTX1, IFNA2, IHH, IRF1, PTPN2, TNFSF4, PGLYRP1, TNFSF18 |
1291 | GO:0048599 | 0.04 | 2.24 | 7.32 | 12 | 25 | oocyte development | ANG, BRCA2, CCNB1, PTK2B, GDF9, IGF1, PPP2R1A, RPS6KA2, ZP3, PDE5A, KIAA0196, REC8 |
1292 | GO:0050982 | 0.04 | 2.24 | 7.32 | 12 | 25 | detection of mechanical stimulus | ATP2B2, CAV3, COL11A1, FYN, HPN, IGF1, ITGA2, JUP, KCNA1, KIT, SLC12A2, PIEZO1 |
1293 | GO:0060986 | 0.04 | 2.24 | 7.32 | 12 | 25 | endocrine hormone secretion | AGTR1, AGTR2, AQP1, CRH, CRHBP, GALR1, GATA3, GDF9, INHA, KISS1, TACR2, FZD4 |
1294 | GO:1900543 | 0.04 | 2.24 | 7.32 | 12 | 25 | negative regulation of purine nucleotide metabolic process | TSPO, DRD3, LPAR1, EDNRA, EDNRB, GALR1, GNAI3, PALM, SNCA, STAT3, AKAP6, GABBR2 |
1295 | GO:0001501 | 0.00 | 2.24 | 74.04 | 120 | 253 | skeletal system development | ACP2, ACVR2B, ACVRL1, AEBP1, AES, ALX3, ARSE, ATP6AP1, BGLAP, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, RUNX2, CD44, CHAD, CMKLR1, COL1A1, COL2A1, COL9A1, COL9A2, COL10A1, COL11A1, COL19A1, COMP, VCAN, CTGF, DLX5, EPHA2, EN1, EP300, ETS2, EXTL1, FBN1, EFEMP1, FGF4, FGF6, FGF8, FGF9, FGFR3, GNAQ, GNAS, GPLD1, HAS2, HEXB, HOXC10, HOXC11, HOXD4, HOXD8, HOXD9, HOXD10, HOXD12, IDUA, IGF1, IGF2, IHH, INHA, INPPL1, INSIG1, KIT, LTF, SMAD1, SMAD3, SMAD9, MATN3, P2RX7, PRDX1, PCSK5, PEX7, PIP4K2A, PPIB, MAPK3, PTH, PTPN6, RARA, RARB, RPL38, RPS6KA3, RYR1, TRAPPC2, SNAI1, SOX4, SOX5, SOX9, SOX11, SP1, SP3, SPARC, SRD5A1, SRF, STC1, T, TAL1, KLF10, CLEC3B, TRPS1, TULP3, TYMS, TYROBP, UFD1L, VDR, WNT1, WNT11, PRKRA, TP63, CHRD, DLK1, SGPL1, PAPSS1, RGN, HAND1, EIF2AK3, ADAMTS4, IFT140, RASSF2, EIF4A3, WASF2, IRX5 |
1296 | GO:0030038 | 0.00 | 2.23 | 14.05 | 23 | 48 | contractile actin filament bundle assembly | ARHGAP6, BBS4, CTGF, S1PR1, LPAR1, PTK2B, ITGB5, LIMK1, SMAD3, PFN2, PRKCQ, RAC1, SDC4, SLC9A1, SRF, TSC1, WNT11, ARHGEF5, CUL3, ITGB1BP1, BAG4, PPM1F, WASF2 |
1297 | GO:0006606 | 0.00 | 2.23 | 25.07 | 41 | 86 | protein import into nucleus | ADAR, AGTR2, ANGPT1, ARNTL, BCL3, CD36, CDKN1A, CSE1L, EMD, F2R, FGF9, GNAQ, IFNG, IL10, JUN, TONSL, NUP98, PRDX1, PPM1B, MAPK1, MAPK3, RAN, SFRP5, SIX3, STAT3, SYK, NUP214, AKAP1, FZD7, DYRK2, RGS20, AKR1C3, RPL23, SLC9A3R1, ZFYVE9, CABP1, LITAF, NUP155, IPO13, NUP93, CEP57 |
1298 | GO:0002526 | 0.01 | 2.23 | 12.82 | 21 | 44 | acute inflammatory response | ADAM8, C3, C7, CD6, CD59, CR1, CD55, FCER1A, GATA3, B4GALT1, FFAR3, ICAM1, CFP, PHB, PRCP, PROS1, S100A8, TNFSF4, VTN, ZP3, VNN1 |
1299 | GO:0045766 | 0.00 | 2.23 | 20.19 | 33 | 69 | positive regulation of angiogenesis | ACVRL1, ANGPT2, ANXA3, AQP1, C3, CCR3, CTSH, CX3CR1, ECM1, ETS1, F3, PTK2B, FLT1, GATA4, GATA6, HGF, HSPB1, IL1A, ISL1, ITGA5, KDR, SERPINE1, PRKCB, PRKD1, PTGIS, PTGS2, RRAS, CX3CL1, NR2E1, VEGFA, VEGFB, TNFSF12, PDCD6 |
1300 | GO:0008284 | 0.00 | 2.23 | 64.47 | 105 | 225 | positive regulation of cell proliferation | ABL1, ADAM10, AGTR2, BIRC5, ARHGAP5, STS, ATF3, AVPR2, BCL2L1, CAPN1, CAV3, RUNX2, CDC20, CDK2, CDX2, CHRM1, CLU, CRH, CRKL, CSF1R, CSF2, CSNK2A1, CTF1, CTGF, CTSH, DPP4, DRD3, EDNRA, EDNRB, EGR4, EIF5A, EMP2, EPOR, ETS1, F2, F2R, PTK2B, EFEMP1, FGF3, FGF4, FGF6, FGF8, FLT3, FLT3LG, FSHB, GDF9, GDNF, GHRHR, HCLS1, HGF, HMX2, HOXC10, HSF4, IGF1R, IL12RB2, ILK, INS, ISL1, ITGAV, ITGB1, KCNA5, KIT, LTF, MFGE8, YBX1, NTRK2, NTRK3, ODC1, PAX3, PRKAA1, MAPK1, PTEN, PTK2, PTPN6, PURA, RAC2, RAD51B, RARA, RARB, REG1A, S100A13, TSPAN31, CXCL5, SHMT2, SLAMF1, SOX4, SRPK2, STAT3, T, ADAM17, TTK, CNBP, ZNF16, FOSL1, CUL4A, CUL3, AKR1C3, CHRD, SERPINB7, TNFSF13, CCPG1, ITGB1BP1, GLP2R, GAB2, FGFBP1 |
1301 | GO:0006366 | 0.00 | 2.23 | 16.91 | 28 | 61 | transcription from RNA polymerase II promoter | BTF3, CSTF3, DTX1, ERCC6, HIVEP2, HLF, SRSF1, SRSF5, SRSF7, SNAPC3, SNAPC4, SNRPE, SNRPF, SSRP1, ZNF141, TTF2, PIR, SRSF9, TAF1A, DDX21, TRIP11, TRIP4, TBPL1, CREB5, ZNF516, DHX38, RBM8A, ALYREF |
1302 | GO:0007565 | 0.00 | 2.23 | 23.88 | 39 | 82 | female pregnancy | ACVR1B, ARHGDIB, STS, BYSL, COMT, CRH, CRHBP, DHODH, EPYC, EMP2, ETS1, FBLN1, FSHB, GNAS, HPGD, IGF1, IGF2, IL11RA, IDO1, ITGA2, OVGP1, OXTR, PCSK5, PRL, PSG2, PSG3, PSG5, PSG6, PSG9, PSG11, PZP, RARA, SP1, SP3, STAT5B, SULT1E1, SCGB1A1, FOSL1, TRIM28 |
1303 | GO:0009126 | 0.00 | 2.22 | 36.88 | 60 | 126 | purine nucleoside monophosphate metabolic process | ADA, ADSS, AK1, AK2, ALDOC, AMPD1, AMPD2, APRT, ARNT, ATP1A2, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V0A1, BAD, BPGM, TSPO, COX8A, COX15, CTNS, DLD, DLG2, DLG3, ENO2, GAPDH, GPI, GUK1, HK2, HPRT1, IGF1, IMPDH1, IMPDH2, INS, LDHC, OGDH, P2RX7, PFAS, PFKFB4, PGAM1, PGK2, PPP2R5D, PRKAA1, PRKAG1, PRPS2, SDHC, SNCA, STAT3, TAZ, UQCRC1, UQCRC2, UQCRH, OGT, COX5A, SLC25A13 |
1304 | GO:0090287 | 0.00 | 2.22 | 18.38 | 30 | 63 | regulation of cellular response to growth factor stimulus | ACVRL1, XIAP, ARNT, BMP4, BMPR2, CAV3, RUNX2, CD63, FGF4, FGF9, FOXD1, FLT1, GATA4, GATA6, GPC3, RBPJ, ILK, ING2, ITGA5, MEN1, OTX2, PRKCB, SOX11, VEGFA, VEGFB, VTN, FZD4, LTBP4, ADAMTS3, FGFBP1 |
1305 | GO:0002709 | 0.05 | 2.22 | 6.73 | 11 | 23 | regulation of T cell mediated immunity | CLC, IFNA2, IL12B, P2RX7, PVR, XCL1, TRAF2, TNFSF4, WAS, ZP3, FZD5 |
1306 | GO:0006509 | 0.05 | 2.22 | 6.73 | 11 | 23 | membrane protein ectodomain proteolysis | ADAM8, ADAM10, GPLD1, IFNG, IL10, P2RX7, PRKCQ, PTPN3, ADAM17, TNFRSF1B, ADAM19 |
1307 | GO:0032689 | 0.05 | 2.22 | 6.73 | 11 | 23 | negative regulation of interferon-gamma production | AXL, GATA3, IL10, INHA, RARA, XCL1, TNFSF4, SCGB1A1, PGLYRP1, IL1RL1, NR1H4 |
1308 | GO:0043525 | 0.05 | 2.22 | 6.73 | 11 | 23 | positive regulation of neuron apoptotic process | ASCL1, ATF4, BAX, CASP9, CDK5, FGFR3, ITGA1, JUN, MAP3K11, SRPK2, BCL2L11 |
1309 | GO:0050853 | 0.05 | 2.22 | 6.73 | 11 | 23 | B cell receptor signaling pathway | ABL1, BAX, BLK, BTK, CTLA4, PRKCB, MAPK1, PTPN6, SYK, LAT2, BCAR1 |
1310 | GO:0072512 | 0.05 | 2.22 | 6.73 | 11 | 23 | trivalent inorganic cation transport | ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, CLTC, DNM2, ATP6V0E1, ATP6V0D1, RAB11B, ATP6V1G1 |
1311 | GO:0052652 | 0.00 | 2.22 | 18.39 | 30 | 63 | cyclic purine nucleotide metabolic process | ABCA1, ADCY1, ADCY7, ADCYAP1R1, AMPD2, AVPR2, CALM3, CRH, DRD3, DRD5, LPAR1, EDNRA, EDNRB, FSHR, GALR1, GCG, GHRHR, GNAI3, GNAS, NTRK2, P2RY11, PALM, PTH, RAF1, VIP, VIPR2, WFS1, AKAP6, GABBR2, AKAP12 |
1312 | GO:1900034 | 0.01 | 2.22 | 12.88 | 21 | 44 | regulation of cellular response to heat | ATR, CAMK2A, CAMK2G, CRYAB, EP300, HSBP1, NUP98, MAPK1, MAPK3, RANBP2, RPA2, RPA3, DNAJC7, NUP214, AAAS, BAG5, BAG4, BAG3, BAG2, NUP155, NUP93 |
1313 | GO:0050679 | 0.01 | 2.21 | 11.64 | 19 | 40 | positive regulation of epithelial cell proliferation | BAD, BMPR1A, DLX5, FGF7, FGF9, B4GALT1, HAS2, HPN, ID1, IGF1, IHH, REG3A, PAX2, PTN, SCN5A, SOX9, SOX11, FZD7, TP63 |
1314 | GO:0046496 | 0.00 | 2.21 | 18.44 | 30 | 63 | nicotinamide nucleotide metabolic process | ALDOC, ARNT, BPGM, DLD, ENO2, GAPDH, GPI, HK2, IDH1, IGF1, INS, MDH2, OGDH, P2RX7, PFKFB4, PGAM1, PGD, PGK2, PPP2R5D, PRKAA1, PRKAG1, PTGIS, PTGS2, RPE, STAT3, PDHX, OGT, KCNAB2, KYNU, TP53I3 |
1315 | GO:0009967 | 0.00 | 2.21 | 204.23 | 322 | 706 | positive regulation of signal transduction | ABAT, ABL1, ABL2, ACPP, ACTN4, ACVR1B, ACVR2B, ACVRL1, ADA, ADAM8, ADRA1B, ALK, ALOX15B, ANGPT1, BIRC3, XIAP, ARAF, ARHGAP4, ARHGAP6, ARNTL, ASCL1, ATP6AP1, ATR, AXL, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, BST2, C3, CALM3, CAMK2A, CAMK2G, CASP10, CAT, CBL, CD3E, CD4, CD8A, CD28, CD36, CD40, CD44, CD63, CD74, CHN1, CHN2, CHUK, CCR1, COL1A1, CRKL, CSF1R, CSF2, CSF2RB, CSNK1D, CSNK2A1, CSPG4, CTF1, CTGF, CTH, CYBA, CYP27B1, DCN, DDX5, DLX5, DRD3, DUSP5, DUSP7, DUSP9, ECM1, EDA, LPAR1, EDNRA, EFNA1, EMP2, EPHA4, EPHA8, EPOR, ERCC6, F2, F2R, F3, F7, F10, PTK2B, FCER1A, FGA, FGF3, FGF4, FGF6, FGF7, FGF8, FGFR3, FGR, FOXD1, FLT3, FLT4, FPR1, FSHR, FYN, FZD2, GATA3, GATA4, GATA6, GCG, GDF9, GPC3, GNAS, GNG3, GPX1, GRB2, GRB7, RAPGEF1, GRIN2A, GRM1, HCLS1, HGF, NRG1, HHEX, HIC1, UBE2K, HMGCR, FOXA2, HPX, PRMT1, HTR2C, ICAM1, IFNA2, IFNG, IGF1R, IGF2, RBPJ, IHH, IL1A, IL2RA, IL2RB, IL2RG, IL3, IL10, IL12B, IL13, IL18, ILK, ING2, INHA, INS, IRAK1, IRAK2, ISL1, ITGA1, ITGAL, ITGB1, JUN, JUP, KCNN4, KDR, KISS1, KIT, LTF, MARK3, MEN1, KITLG, MAP3K11, NTRK2, NTRK3, NTSR1, P2RX3, P2RX4, P2RX5, P2RX7, PHB, PPP5C, PRKAA1, PRKCE, PRKD1, PRKCQ, MAPK1, MAPK3, PRL, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTGIS, PTH, PTGS2, PTK2, PTPN6, PTPRA, PTPRJ, RAC1, RAF1, RAP1A, RASA2, RFNG, RHEB, RPS27A, RYK, S100A4, S100A7, S100A12, S100A13, SALL1, CCL21, CCL22, CCL25, XCL1, CX3CL1, SELP, SH3BGR, SH3BGRL, SH3BP2, ITSN1, SHB, SHC1, SKP2, SLA, SLAMF1, SLC9A1, SLC12A1, SLC20A1, SMARCA4, SOS2, SOX4, SOX9, SOX11, SPTA1, SPTB, STAT3, XCL2, SYK, ADAM17, CNTN2, TNFRSF1A, TNFRSF1B, NR2C1, TRIP6, TTK, UBE2V1, UBE3A, WNT11, TRIM25, ZP3, FZD5, ARHGEF5, SHOC2, FGF23, FZD4, FZD7, FZD8, CUL3, SEMA7A, CNTNAP1, IKBKG, MADD, AKR1C3, PDE5A, TNKS, TNFSF14, RIPK2, TNFRSF18, IL18R1, NRP1, BUD31, TNFSF18, DGKI, BMP15, VAPA, ITGB1BP1, GPR55, KL, NRXN1, GRAP2, GSTO1, AKAP6, PSMF1, ADAMTS3, LITAF, GDF15, BAG4, NRG2, AKAP12, TRAF4, RAPGEF2, PUM1, RIMS2, USP34, RASSF2, ZEB2, TNFSF15, RBX1, FGFBP1, HDAC6, FRAT1, SH2D3C, SH2D3A, AKAP9, RASA4, ATP6AP2, PSME3, PSMD14 |
1316 | GO:0030801 | 0.01 | 2.21 | 12.28 | 20 | 42 | positive regulation of cyclic nucleotide metabolic process | ABCA1, ADCY7, ADCYAP1R1, AVPR2, CALM3, CRH, DRD5, EDNRA, FSHR, GCG, GHRHR, GNAS, NTRK2, P2RY11, PTH, RAF1, VIP, VIPR2, WFS1, AKAP12 |
1317 | GO:0009790 | 0.00 | 2.21 | 69.18 | 112 | 241 | embryo development | ACVR1B, ACVR2B, ACVRL1, ADAM10, ADAR, ADD1, APLNR, ANGPT1, APAF1, BAX, BCL2L1, BMPR2, BRCA2, BTF3, BYSL, CCNB1, COL1A1, COL6A1, DAD1, DDX5, DLD, DMBT1, DNMT3A, DSC3, DUSP1, DUSP5, EDNRA, EFNB1, ELF3, EMX1, EN1, ETS2, ETV2, EVX1, EXT2, EYA2, FGF4, FLT1, NR5A2, FUT8, GATA6, GPC3, GNAQ, NRG1, HOXC10, HOXD8, HOXD12, HSBP1, ISL1, ITGA2, ITGA5, ITGA7, ITGAV, ITGB1, ITGB5, SMAD1, SMAD6, CNOT2, YBX1, OCRL, OPA1, P2RY2, PRKAR1A, PSMC3, PSMC4, PTK2, PTPRR, RALA, RBBP8, RCN1, RET, RNF2, RXRA, SDC4, SEMA3F, SRSF1, SIM2, SOX4, SOX5, SOX10, TOP1, TOP2A, TSC1, VTN, ZBTB17, SLC30A1, ZP3, FOSL1, IFT88, USP9X, CUL4A, CUL3, COPS3, TP63, CHRD, DLK1, SCEL, EIF2S2, LATS1, CCNB2, TRIP12, SLIT2, PICK1, APBA3, IFT140, GINS1, MFN2, BCL2L11, FRAT1, COL4A3BP, ARFRP1, ATP6AP2 |
1318 | GO:0048584 | 0.00 | 2.21 | 22.95 | 38 | 85 | positive regulation of response to stimulus | ADAM10, ALB, APBB1, BNIP3L, CEBPG, CMKLR1, CRH, S1PR1, CXCL2, CXCL3, HMGA1, HSPB1, KCNK2, MGMT, ATXN3, OXCT1, PCNA, PENK, PF4V1, PIP4K2A, RAC2, CXCL6, CXCL5, SETMAR, SNCA, NR2C2, TRPC3, TRPM2, SCG2, PIK3R3, RNF8, RGN, SLIT2, ATG5, CXCL14, BRE, PPM1F, TRIM28 |
1319 | GO:1901343 | 0.01 | 2.21 | 12.29 | 20 | 42 | negative regulation of vasculature development | ANGPT2, APOH, KLK3, ADGRB2, BMP4, KRIT1, COL4A3, CX3CR1, DCN, GTF2I, HHEX, HRG, FOXO4, SERPINE1, SERPINF1, PTN, SPARC, ITGB1BP1, KLF4, SEMA3E |
1320 | GO:0006323 | 0.00 | 2.21 | 28.97 | 47 | 99 | DNA packaging | ATRX, CCNB1, CENPA, DFFB, CENPI, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, HIST1H2BB, H3F3B, HIST1H1A, HMGA1, CHMP1A, PRM2, RBBP4, SET, SOX9, TOP2A, TSPY1, CHAF1B, HIST1H4I, HIST1H2BL, HIST1H2BN, HIST1H2BM, HIST1H2BF, HIST1H2BH, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, HAT1, RUVBL1, HIST1H3F, SMC4 |
1321 | GO:0018105 | 0.00 | 2.20 | 22.15 | 36 | 76 | peptidyl-serine phosphorylation | ADRBK1, ATR, BAX, CAMK2A, CCNB1, CDK2, CDK5, CLK1, CSNK1D, CSNK1G3, HRC, ILK, SMAD7, PDPK1, PRKAA1, PRKCB, PRKCE, PRKCI, PRKCQ, MAPK1, MAPK3, PRKX, RPS6KA2, SGK1, SYK, VRK1, OGT, TNKS, RIPK1, RPS6KA4, AURKB, RPS6KA5, EIF2AK3, PPM1F, RASSF2, SGK2 |
1322 | GO:0017157 | 0.00 | 2.20 | 28.39 | 46 | 97 | regulation of exocytosis | ANXA1, ARF1, ATP6AP1, BCR, CACNA1A, CDK5, FCER1A, FGA, FGR, B4GALT1, GLRA1, IFNG, IL13, IL13RA2, PDPK1, PFN2, SEPT5, PTAFR, RAB3A, RAB3B, RAB5A, RAB27A, RAC2, RALA, RAP1A, REST, SDC1, SDC4, SNCA, SPINK1, STXBP2, STXBP3, SYK, SYN1, SYT1, SYT4, TSG101, ZP3, VAMP8, CD84, SYT7, RAB9A, RIMS2, RIMS3, GAB2, PDCD6IP |
1323 | GO:0032869 | 0.02 | 2.20 | 9.18 | 15 | 32 | cellular response to insulin stimulus | APRT, CDK2, GHRHR, GHSR, FFAR3, HMGCS2, IGF1, RAB8A, PRKCI, RXRA, SRSF5, SLC2A4, SLC9A1, SRD5A1, USF1 |
1324 | GO:0051604 | 0.00 | 2.20 | 57.07 | 92 | 195 | protein maturation | ADAM8, ADAM10, AEBP1, ANPEP, APAF1, BIRC3, XIAP, BIRC5, APOH, BAD, BAX, BGLAP, BOK, C3, C7, CASP8, CASP9, CD14, CD59, CLN5, COL4A3, CR1, CTSE, CTSG, CTSH, CTSS, CD55, ACE, ENPEP, F2, F2R, F3, F7, F10, F12, FGA, FSHB, GAS1, GZMH, HIP1, HPN, IFI16, IHH, KLKB1, SMAD3, P2RX1, P2RX7, SERPINE1, PCSK5, CFP, PHB, PRKACB, PROC, PROS1, PTCH1, RET, RFX4, RPS6KA2, RPS27A, S100A8, S100A9, SNCA, SORL1, CNTN2, CLEC3B, TRAF2, TSG101, UBB, UQCRC1, UQCRC2, VTN, WFS1, IFT88, TRADD, RIPK1, CRADD, TNFSF10, TNFRSF10B, TNFRSF10A, PROZ, PCSK7, EIF2AK3, ADAMTS3, ADAMTS2, TMEM59, SPCS2, TNFSF15, CASP8AP2, PDCD6, BCL2L11, ATP6AP2, ZMPSTE24 |
1325 | GO:0009581 | 0.00 | 2.20 | 27.17 | 44 | 93 | detection of external stimulus | ABCA4, OPN1SW, CACNB4, CALM3, AKR1C4, CHRM1, CLPS, CNGA1, EPHB1, GPC4, GPC5, FNTA, OPN1MW, GPC3, GNAQ, GNAT1, GNAT2, GNGT1, GNGT2, GPC1, GUCA1A, GUCY2F, GUCY2D, NTSR1, PRKCQ, RBP1, RBP2, OPN1LW, RCVRN, RGR, RLBP1, SDC1, SDC4, ELOVL4, TRPC3, TULP1, TRPV1, LRP8, AKR1C3, RGS9, UNC119, GUCA1C, SDC3, NR2E3 |
1326 | GO:0034644 | 0.01 | 2.20 | 11.71 | 19 | 40 | cellular response to UV | AQP1, ATF4, ATR, BAX, CASP9, CDC25A, CDKN1A, CHEK1, DDB1, EP300, ERCC4, PCNA, PPID, PTGS2, PTN, TP73, YY1, TP63, AURKB |
1327 | GO:0060840 | 0.01 | 2.20 | 11.71 | 19 | 40 | artery development | ACVR2B, ACVRL1, AP2B1, PRDM1, BMP4, BMPR2, DNM2, FGF8, HPGD, RBPJ, SMAD6, SMAD7, PROX1, SOX4, SRF, VEGFA, WNT11, NRP1, SNX17 |
1328 | GO:0032944 | 0.00 | 2.19 | 32.19 | 52 | 110 | regulation of mononuclear cell proliferation | ADA, AHR, ANXA1, PRDM1, BMP4, CBLB, CD3E, CD4, CD6, CD28, CD86, CD40, CD59, CD74, CDKN1A, CHRNB2, CLC, CTLA4, CD55, DHPS, EFNB1, IFNG, IGF1, IGF2, IHH, IL2RA, IL10, IL12B, IL13, IL18, IDO1, IRF1, ITGAL, LMO1, PRKAR1A, PRKCQ, PTPN6, RAC2, XCL1, SFTPD, SOS2, SOX11, SPTA1, STAT5B, SYK, TNFSF4, SCGB1A1, ZP3, PDE5A, TNFSF9, RIPK2, TNFSF18 |
1329 | GO:0016337 | 0.00 | 2.19 | 15.95 | 26 | 56 | single organismal cell-cell adhesion | ACTB, CDH7, CDH9, CDH10, COL19A1, CSRP1, CTNND1, CTNND2, GNAS, RAPGEF1, HSPB1, ICAM2, ICAM4, ILK, RAP2B, SHC1, SIGLEC1, SOX9, STXBP3, ICAM5, TYRO3, COL14A1, ZAN, SLIT2, PTPRU, GPA33 |
1330 | GO:0052548 | 0.00 | 2.19 | 19.11 | 31 | 66 | regulation of endopeptidase activity | APAF1, BAD, BAX, BOK, CASP9, CD14, CTGF, CTSH, F2R, F3, HIP1, SMAD3, MGMT, P2RX1, PSMA3, REST, RET, RPS3, S100A8, S100A9, TP63, CRADD, EIF2AK3, PPM1F, KIAA0141, TNFSF15, CASP8AP2, PDCD6, BCL2L11, PSME3, PSMD14 |
1331 | GO:0019882 | 0.00 | 2.19 | 40.93 | 66 | 140 | antigen processing and presentation | AP2B1, ARF1, CANX, CD8A, CD36, CD74, CENPE, AP2M1, AP1S1, AP2S1, CLTC, CTSE, CTSH, CTSS, CYBA, ACE, DYNC1H1, DNM2, FCGRT, ICAM1, IFNG, ITGAV, ITGB5, KIF5A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RAB3B, RAB4A, RAB5B, RAB6A, RAB27A, RPS27A, CCL21, UBB, WAS, KDM5D, DYNLL1, CTSF, AP1M1, RAB33A, KIF3B, PSMF1, AP1M2, ACTR1A, PSME3, PSMD14 |
1332 | GO:0030098 | 0.01 | 2.19 | 14.17 | 23 | 49 | lymphocyte differentiation | ABL2, BMX, ZFP36L2, RUNX2, CD3D, CD3E, CD4, CD8A, TNFSF8, CDK6, RPL22, SATB1, SOX4, SRF, STAT6, TSC1, TYRO3, WNT1, FZD5, EOMES, FZD7, FZD8, IL18R1 |
1333 | GO:0010976 | 0.00 | 2.19 | 31.61 | 51 | 108 | positive regulation of neuron projection development | ABL2, APBB1, ARF1, BMP4, BMPR2, CNR1, DPYSL3, LPAR1, EFNA5, EPHA3, EPHA4, EPOR, PTK2B, FYN, GOLGA4, RAPGEF1, HGF, NRG1, ILK, ITGB1, LIMK1, CAPRIN1, MAP1B, NTRK2, NTRK3, OPA1, P2RY2, PALM, PCP4, SERPINF1, PRKCI, PRKD1, PTN, PTPRZ1, RAP1A, RET, SGK1, SRF, SYT1, SYT4, VEGFA, LRP8, RND2, SF3A2, SEMA7A, NRP1, CBFA2T2, SLIT2, RAPGEF2, RIMS2, CUL7 |
1334 | GO:0048699 | 0.00 | 2.19 | 224.84 | 351 | 776 | generation of neurons | ABL1, ABL2, ACTB, ADAM10, ADCY1, AP2B1, ALK, BIN1, ANGPT1, APBB1, APP, ARAF, ARF1, ARF4, ARHGAP4, PHOX2A, ARNTL, ASCL2, RERE, ATP2B2, PRDM1, BMP4, BMPR1A, BMPR2, BYSL, TSPO, CACNA1A, CACNB1, CACNB2, CACNB4, CALM3, CAMK2A, CAMK2G, RUNX2, CD72, CDC20, CDH1, CDK6, CHN1, CHRNB2, AP2M1, AP2S1, CLU, CLN5, CNP, CNR1, COL2A1, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CRX, CSF2, CSF2RB, CSNK2A1, CSNK2A2, CTF1, CTNND2, DAPK3, BRINP1, DBN1, DDX6, DHFR, DLG3, DLX5, DNM1, DNM2, DNMT1, DNMT3A, DNMT3B, DPYSL3, DRD3, EPYC, DTX1, DUSP5, DUSP7, DUSP9, S1PR1, LPAR1, EDNRB, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EFNB2, EGR2, EPHA2, EIF4E, EMX1, CTTN, EMX2, EN1, EPHA3, EPHA4, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, EPOR, ERCC3, ETV1, ETV4, ETV5, EVX1, F2, PTK2B, EFEMP1, FGF3, FGF4, FGF6, FGF7, FGF9, FGFR3, FZD2, GABRA5, GABRB2, GDI1, GDNF, GFAP, GFRA1, GNAT1, GNAT2, GNGT1, GOLGA4, GPC1, GRB2, RAPGEF1, GRID2, GRIN2A, HGF, FOXA2, HOXC10, HOXD9, HOXD10, HPRT1, PRMT1, ID1, ID2, IFNG, RBPJ, IHH, IL2RA, IL2RB, IL2RG, IL3, ILK, ISL1, ITGA1, ITGA2, ITGA5, ITGA9, ITGAV, ITGB1, JUN, KIF5A, KIT, LIMK1, CAPRIN1, MAP1B, MARK3, RAB8A, KITLG, NTF4, NTN3, OPA1, OPHN1, OTX2, P2RY2, PALM, PAX2, PAX3, PCP4, SERPINF1, PPP5C, PPT1, PRKCI, PRKD1, PRKCQ, MAPK1, MAPK3, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTCH1, PTEN, PTN, PTPRA, PTPRR, RAB3A, RAC2, RAF1, RAP1A, RAP1GAP, RAP2A, RARA, RARB, RASA2, RB1, REST, RET, RHEB, RNF6, RPGR, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RRAS, RXRA, RYK, SCN5A, SDC4, SEMA3F, SGK1, ITSN1, SHC1, SIAH2, SLC6A4, SMARCA1, SNAP25, SORL1, SOS2, SOX3, SOX4, SOX9, SOX11, SPTA1, SPTB, STRN, SYT1, SYT4, TAL1, TBCE, DYNLT1, TNR, TP73, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TTC3, TULP1, TULP3, TYROBP, UGT8, CLRN1, VCL, VIM, WNT1, WNT11, XRCC2, XRCC5, YWHAH, RNF112, LRP8, FZD5, SEMA3B, FGF23, IFT88, RND2, SF3A2, PICALM, EOMES, FZD4, FZD7, FZD8, CUL3, SEMA7A, CNTNAP1, GAS7, KLF7, UNC5C, PEA15, IQGAP1, NRP2, ARHGEF7, RPS6KA4, ARHGEF1, CBFA2T2, ARHGEF2, VAPA, RPS6KA5, KLF4, COPS2, KL, SLC9A3R1, NRXN3, NRXN1, PICK1, CHST3, ONECUT2, PSMF1, SLC4A7, BAG5, NRG2, AATK, FEZ2, RIMS2, SEMA3E, IFT140, ZNF536, CUL7, ARHGEF11, RNF10, WDR1, RBX1, NR2E3, RANBP9, PQBP1, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, FRY, AKAP9, RASA4, FARP1, PSME3, PSMD14, OLIG2, IRX5 |
1335 | GO:0032729 | 0.01 | 2.18 | 11.12 | 18 | 38 | positive regulation of interferon-gamma production | ABL1, ABL2, BCL3, CD3E, CD14, CEBPG, IL12B, IL12RB2, IL18, ISL1, PDE4B, TNFSF4, ZP3, FZD5, TNFSF9, RIPK2, IL18R1, IL27RA |
1336 | GO:1901019 | 0.01 | 2.18 | 11.12 | 18 | 38 | regulation of calcium ion transmembrane transporter activity | ATP1A2, BMP4, CACNB1, CACNB2, CACNB4, CALM3, CASQ2, CAV3, HRC, PDE4B, PLN, RYR2, S100A1, SLC9A1, SUMO1, RGN, GSTO1, AKAP6 |
1337 | GO:0010647 | 0.01 | 2.18 | 14.00 | 23 | 51 | positive regulation of cell communication | BNIP3L, CHRNB2, CHRNB4, CX3CR1, DBI, DNM1, GFAP, ITGA2, ITPR3, OXTR, PIP4K2A, PTN, RAB3B, SLC8A3, SNAP25, SNCA, STAU1, SYT1, TACR2, NR2E1, TNR, SYNJ1, ATG5 |
1338 | GO:1900544 | 0.00 | 2.18 | 16.08 | 26 | 55 | positive regulation of purine nucleotide metabolic process | ABCA1, ADCY7, ADCYAP1R1, ARNT, AVPR2, CALM3, CRH, DRD5, EDNRA, FSHR, GCG, GHRHR, GNAS, IGF1, INS, NTRK2, P2RX7, P2RY11, PRKAA1, PTH, RAF1, STAT3, VIP, VIPR2, WFS1, AKAP12 |
1339 | GO:0031398 | 0.00 | 2.18 | 35.41 | 57 | 121 | positive regulation of protein ubiquitination | ANGPT1, BIRC3, XIAP, AVPR2, BMI1, CAV3, CCNB1, CDC20, CDC27, CLU, PTK2B, FGFR3, DNAJB2, SMAD7, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, RPS27A, SKP1, SKP2, SUMO3, UBB, UBE2D1, UBE2L3, UBE3A, WFS1, AIMP2, CUL1, CDC14B, CDC23, RIPK2, CDC16, PSMF1, RNF40, PSME3, PSMD14 |
1340 | GO:0060047 | 0.00 | 2.18 | 23.52 | 38 | 81 | heart contraction | ADA, AGTR2, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, CACNA1B, CACNB1, CACNB2, CACNB4, CACNG1, CASQ1, CXADR, ACE, GPX1, IFNG, ITPR1, ITPR3, KCND2, KCND3, KCNJ11, KCNJ14, KCNK3, FXYD3, RPS6KA2, RYR1, S100A1, SGCD, SLC8A3, SREBF1, TACR3, TRPC1, KCNK6, ATG5, ABCC9, AKAP9, IRX5 |
1341 | GO:0048469 | 0.01 | 2.17 | 14.86 | 24 | 51 | cell maturation | ANG, ASCL1, AXL, BFSP1, BRCA2, BTK, RUNX2, CCNB1, DLD, PTK2B, GATA3, GHRHR, ID2, IHH, KDR, PPP2R1A, RPS6KA2, CCL21, SOX10, TAL1, VEGFA, FZD5, KIAA0196, REC8 |
1342 | GO:0001570 | 0.02 | 2.17 | 10.54 | 17 | 36 | vasculogenesis | EPHA2, EMP2, HAS2, HHEX, JUNB, KDR, NTRK2, PTK2, PTPRJ, RAP1A, T, TNNI3, VEGFA, FZD4, SGPL1, RAPGEF2, CUL7 |
1343 | GO:0021872 | 0.02 | 2.17 | 10.54 | 17 | 36 | forebrain generation of neurons | ASCL1, CSF1R, DCT, FGF8, GNAQ, OGDH, PROX1, RAC1, RAC3, SALL1, CNTN2, NR2E1, UBB, NUMB, NRP1, SLIT2, RAPGEF2 |
1344 | GO:0032414 | 0.02 | 2.17 | 10.54 | 17 | 36 | positive regulation of ion transmembrane transporter activity | ACTN4, BMP4, CALM3, CTSS, DNM2, KCNJ11, NTSR1, PTAFR, RYR2, S100A1, SLC9A1, SUMO1, RGN, GSTO1, AKAP7, AKAP6, AKAP9 |
1345 | GO:0032663 | 0.02 | 2.17 | 10.54 | 17 | 36 | regulation of interleukin-2 production | ABL1, ABL2, ANXA1, CD3E, CD4, CD28, CD86, GATA3, IL1A, PDE4B, PRKCQ, XCL1, SFTPD, STAT5B, TRAF2, TNFSF4, RIPK2 |
1346 | GO:0045841 | 0.02 | 2.17 | 10.54 | 17 | 36 | negative regulation of mitotic metaphase/anaphase transition | BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DUSP1, MAD2L1, TTK, UBE2D1, ZNF207, CDC23, CDC16, ZW10, BUB3 |
1347 | GO:0042035 | 0.00 | 2.17 | 15.51 | 25 | 53 | regulation of cytokine biosynthetic process | BCL3, CD3E, CD4, CD28, CD86, TNFRSF8, CEBPG, FCER1A, GATA3, GHSR, HSPB1, IFNG, IL1A, IL10, IL12B, INHA, IRF1, PRG2, PRKCQ, PTAFR, SFTPD, STAT5B, SYK, KLF4, PRG4 |
1348 | GO:0099504 | 0.00 | 2.17 | 15.51 | 25 | 53 | synaptic vesicle cycle | AMPH, CACNA1A, CANX, CDK5, CLCN3, DNM1, OPHN1, P2RX7, PFN2, SEPT5, RAB3A, RAB5A, RAP1A, ITSN1, SNAP25, SNCA, SYN1, SYT1, SYT5, STX11, SNAP23, SYNJ1, SNAP29, RIMS2, RIMS3 |
1349 | GO:0007169 | 0.00 | 2.17 | 32.62 | 53 | 117 | transmembrane receptor protein tyrosine kinase signaling pathway | ALK, ANGPT2, APLP2, APP, ARF4, BLK, BMX, BTK, CAMLG, CD3E, CD4, CD7, CD8A, CSF1R, CSH1, CSPG4, DOK1, EPS15, EFEMP1, FGR, GFRA1, GH2, GHRHR, GHSR, GRB7, HGF, IGF1, IGF2R, IGFBP3, IGFBP6, INSRR, ITGA1, NTF4, DDR2, PRL, PTPN6, PTPRR, RET, ATXN7, SOX9, STAT5B, SYK, TYK2, VIL1, WNT1, IFT88, DOK2, ANGPTL1, REPS2, EIF2AK3, RASSF2, GAB2, STAM2 |
1350 | GO:0009161 | 0.00 | 2.17 | 38.63 | 62 | 132 | ribonucleoside monophosphate metabolic process | ADA, ADSS, AK1, AK2, ALDOC, AMPD1, AMPD2, APRT, ARNT, ATP1A2, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V0A1, BAD, BPGM, TSPO, COX8A, COX15, CTNS, DHODH, DLD, DLG2, DLG3, ENO2, GAPDH, GPI, GUK1, HK2, HPRT1, IGF1, IMPDH1, IMPDH2, INS, LDHC, OGDH, P2RX7, PFAS, PFKFB4, PGAM1, PGK2, PPP2R5D, PRKAA1, PRKAG1, PRPS2, SDHC, SNCA, STAT3, TAZ, UPP1, UQCRC1, UQCRC2, UQCRH, OGT, COX5A, SLC25A13 |
1351 | GO:0046390 | 0.00 | 2.16 | 42.44 | 68 | 145 | ribose phosphate biosynthetic process | ABCA1, ACACB, ADCY1, ADCY7, ADCYAP1R1, ADSS, AK1, AK2, AMPD1, AMPD2, APRT, AQP1, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V0A1, AVPR2, CALM3, CRH, DHODH, DRD3, DRD5, LPAR1, EDNRA, EDNRB, PTK2B, FSHR, GALR1, GCG, GHRHR, GNAI3, GNAS, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GUK1, GUCY2D, HPRT1, HTR2C, IMPDH1, IMPDH2, LDHC, NTRK2, P2RY11, PALM, PFAS, PRPS2, PTH, RAF1, RCVRN, STAT3, UPP1, VIP, VIPR2, WFS1, PAPSS1, AKAP6, GABBR2, AKAP12, GUCA1C, SLC25A13 |
1352 | GO:0051241 | 0.00 | 2.16 | 87.18 | 139 | 303 | negative regulation of multicellular organismal process | ABAT, ACVRL1, ADA, ANPEP, ANXA5, APP, ARHGAP4, ARHGDIB, ASCL1, ASCL2, ATP2A1, AVPR2, BCR, BMPR1A, BRCA2, CD86, CD63, CDK5, CHAD, CCR1, COMT, CRHBP, CTNNA1, CYBA, DCC, DDX6, DPYSL3, DRD3, TSC22D3, ECM1, LPAR1, EDNRB, EFNA1, EIF4E, EPHA4, ETV4, F2, F12, FAP, EFEMP1, FGA, FGF3, FGF8, FGFR3, GDI1, GFAP, GLRA1, GNAS, GP1BA, NRG1, FOXA2, HPN, IAPP, ID1, IGF1, RBPJ, ISL1, ITGB1, KLKB1, KNG1, LRPAP1, SMAD3, SMAD7, MEN1, CIITA, NTRK3, OXTR, P2RX4, P2RX7, P2RY2, REG3A, PAX2, PCM1, PDE4B, PFN2, PRKACB, PRKG1, PROC, PROS1, PTCH1, PTGS2, PTPRR, PTPRZ1, RAP1A, RAP1GAP, RARB, REST, RFX4, RNF6, RPS19, SALL1, SEMA3F, SFRP5, SIX3, SNAI1, SORL1, SOX3, SOX9, SOX11, SP100, SPOCK1, SRF, STAT3, STC1, CNTN2, DYNLT1, NR2F2, NR2E1, TNR, TTC3, TULP3, USF1, VIM, VTN, YWHAH, SEMA3B, FZD3, FGF23, AKAP1, FZD7, TP63, CHRD, NRP1, PHOX2B, USP2, RGN, ARHGEF1, CBFA2T2, ARHGEF2, SLIT2, EIF2AK3, BAG5, AATK, PHF14, RAPGEF2, ZNF536, KIAA0319, RNF10, OLIG2 |
1353 | GO:0071347 | 0.02 | 2.16 | 9.93 | 16 | 34 | cellular response to interleukin-1 | BYSL, HAS2, HSPA9, ICAM1, P2RY2, PPP4C, PTGIS, UPF1, CCL21, CCL22, CCL25, XCL1, CX3CL1, SOX9, XCL2, YY1 |
1354 | GO:0051784 | 0.01 | 2.16 | 14.93 | 24 | 51 | negative regulation of nuclear division | ATRX, BMP4, BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, CHEK1, CSNK2A1, CSNK2A2, DUSP1, FGFR3, MAD2L1, PRKAR1A, RPS6KA2, TTK, UBE2D1, ZNF207, TNKS, CDC23, CDC16, ZW10, BUB3 |
1355 | GO:0009314 | 0.00 | 2.16 | 15.48 | 25 | 54 | response to radiation | ALAD, ANGPT2, ANXA1, DNMT1, DNMT3A, DNMT3B, FANCG, ICAM1, IGF2, IL1R1, JUN, KRT13, KRT14, PENK, RAD51C, RAD51B, RAD51D, RRM1, XRCC2, SMC1A, PPM1D, MBD4, SOCS3, RNF8, BRE |
1356 | GO:0045670 | 0.02 | 2.16 | 9.95 | 16 | 34 | regulation of osteoclast differentiation | ATP6AP1, BGLAP, CCR1, CREB1, CSF1R, FSHB, FSHR, GNAS, IFNG, IL12B, LTF, KLF10, TYROBP, INPP4B, GPR55, RASSF2 |
1357 | GO:0009582 | 0.00 | 2.15 | 27.46 | 44 | 94 | detection of abiotic stimulus | ABCA4, OPN1SW, CACNB4, CALM3, AKR1C4, CHRM1, CLPS, CNGA1, EPHB1, GPC4, GPC5, FNTA, OPN1MW, GPC3, GNAQ, GNAT1, GNAT2, GNGT1, GNGT2, GPC1, GUCA1A, GUCY2F, GUCY2D, NTSR1, PRKCQ, RBP1, RBP2, OPN1LW, RCVRN, RGR, RLBP1, SDC1, SDC4, ELOVL4, TRPC3, TULP1, TRPV1, LRP8, AKR1C3, RGS9, UNC119, GUCA1C, SDC3, NR2E3 |
1358 | GO:0051170 | 0.00 | 2.15 | 44.48 | 71 | 152 | nuclear import | ADAR, AGTR2, ANGPT1, ARNTL, RERE, BCL3, BMP4, BMPR1A, CBLB, CD36, CDH1, CDKN1A, CSE1L, EDA, EMD, F2R, FGF9, FYB, GNAQ, HCLS1, IFNG, IGF1, IL10, IL12B, IL18, JUN, JUP, KPNA1, KPNA2, KPNA3, KPNA4, IPO5, SMAD3, TONSL, NUP98, PRDX1, PPM1B, PRKCQ, MAPK1, MAPK3, PTGS2, RAN, RANBP2, SFRP5, SIX3, SLC9A1, STAT3, SYK, TRIP6, TRPS1, ZIC1, NUP214, AKAP1, FZD7, DYRK2, RGS20, AKR1C3, TNFSF14, IL18R1, RPL23, SLC9A3R1, ZFYVE9, AKAP6, CABP1, LITAF, NUP155, IPO13, NUP93, CEP57, TRIM28, NUTF2 |
1359 | GO:0045861 | 0.00 | 2.15 | 67.31 | 107 | 230 | negative regulation of proteolysis | BIRC3, XIAP, BIRC5, APLP2, APP, AQP1, BST2, BUB1, BUB1B, C3, CASP8, CCNB1, CD44, CD59, CDC20, CDC27, CDK5, CDKN2D, CENPF, COL4A3, COL6A3, CR1, CRYAB, CSNK2A1, CSNK2A2, CST1, CST6, CD55, DDX3X, DPEP1, DUSP1, ECM1, SERPINB1, F2, IFI6, GAS1, GPC3, GPI, GPX1, HGF, HRG, DNAJB2, IFI16, IL10, INS, ITIH1, ITIH2, ITIH4, KNG1, MAD2L1, OPHN1, SERPINE1, PAX2, SERPINA5, SERPINF1, SERPINA4, SERPINB5, SERPINB6, SERPINB9, SERPINI1, SERPINB13, SERPINI2, PROS1, PTPN3, PZP, RAF1, RAG1, RENBP, RPS6KA1, RPS6KA3, SERPINB4, SIAH2, SLPI, SMARCC1, SNCA, SORL1, SPINK1, SPOCK1, TRIM21, SERPINA7, TRAF2, TTK, UBE2D1, NR1H2, VEGFA, VIL1, VTN, WNT1, ZNF207, PICALM, CDC23, SERPINB7, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, CDC16, USP14, ZW10, BUB3, KLF4, PSMF1, TMEM59, BAG5, HDAC6 |
1360 | GO:0000077 | 0.00 | 2.15 | 27.51 | 44 | 94 | DNA damage checkpoint | ATR, CDK2, CDKN1A, CHEK1, FOXO4, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RBBP8, RPA2, RPS27A, SOX4, TP73, UBB, CUL4A, CDC14B, TP63, PEA15, CRADD, PSMF1, CLOCK, BRE, FEM1B, PSME3, PSMD14 |
1361 | GO:0001764 | 0.00 | 2.15 | 23.12 | 37 | 79 | neuron migration | APBB2, ASCL1, ASTN1, AXL, BAX, BBS4, CDK5, DCC, CELSR2, FYN, GATA3, GPM6A, NRG1, NRCAM, NTRK2, NTRK3, PCM1, PEX7, PEX13, PRKG1, PTK2, PTPRZ1, SPOCK1, SRF, STAT3, CNTN2, NR2F1, NR2F2, TOP2B, FZD3, USP9X, SOX14, NRP1, PHOX2B, DCLK1, RAPGEF2, KIAA0319 |
1362 | GO:0050805 | 0.03 | 2.14 | 9.36 | 15 | 32 | negative regulation of synaptic transmission | ARF1, BCHE, DRD5, PTK2B, GNAI1, GPM6B, GRIA1, PTEN, RAP1A, SRF, TNR, SLC30A1, DGKI, PICK1, EIF4A3 |
1363 | GO:0060173 | 0.00 | 2.14 | 26.92 | 43 | 92 | limb development | ALX3, ATRX, BAX, BMP4, BMPR1A, BMPR2, RUNX2, COL2A1, COMP, DLX5, EN1, FGF4, FGF8, FGF9, GPC3, GNAQ, GNAS, HOXC10, HOXC11, HOXD9, HOXD10, HOXD12, IDUA, IHH, ITGA6, MEOX2, PAM, PCSK5, PTCH1, RARA, RARB, SALL1, SOX4, SOX9, SOX11, NR2F2, TULP3, ZNF141, IFT88, FZD6, TP63, IFT140, BCL2L11 |
1364 | GO:0048538 | 0.03 | 2.14 | 9.37 | 15 | 32 | thymus development | ABL1, CACNB4, CRKL, EPHB3, FGF3, GATA3, JARID2, MAPK1, MAPK3, RAF1, RAG1, SRF, TYR, CCNB2, BCL2L11 |
1365 | GO:0060425 | 0.03 | 2.14 | 9.37 | 15 | 32 | lung morphogenesis | BMP4, CTSH, FGF7, FGF8, GATA4, HHEX, FOXA2, ID1, IGF1, MAPK1, MAPK3, SOX9, SOX11, SRF, SPRY1 |
1366 | GO:0044033 | 0.00 | 2.14 | 35.12 | 56 | 120 | multi-organism metabolic process | EP300, ERCC3, FAU, HPN, JUN, NUP98, RANBP2, REST, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, SMARCA4, SP1, SP100, TRIM21, SSRP1, TARBP2, TOP2A, TSG101, UBB, USF1, NUP214, AAAS, RPL14, CTDP1, RPL23, ATG5, NUP155, NUP93 |
1367 | GO:0060627 | 0.00 | 2.14 | 40.12 | 64 | 138 | regulation of vesicle-mediated transport | ABL1, ABL2, ACTN4, BIN1, ANGPT1, AXL, BICD1, BLK, C3, CAV3, CBL, CD14, CD36, SCARB1, CD63, AP2S1, CYBA, DNM1, DNM2, GAS1, GPC3, HIP1, INSIG1, ITGA2, ITGAV, ITGB1, MFGE8, OPHN1, SERPINE1, PPT1, PRKAA1, PRKD1, MAPK1, MAPK3, PROS1, PTEN, RAB4A, RAB5B, RAC1, RAP1GAP, CCL21, SELE, SFTPD, SLAMF1, SORL1, TULP1, NR1H2, UVRAG, VEGFA, VTN, PICALM, NRP1, SYNJ1, UNC119, USP6, RAB11B, PICK1, GOSR1, RUBCN, ZFYVE16, SNX17, DNAJC6, C2CD5, SNAP91 |
1368 | GO:0002695 | 0.00 | 2.14 | 22.53 | 36 | 77 | negative regulation of leukocyte activation | ANXA1, AXL, BCR, PRDM1, BMP4, BPI, CBLB, CD37, CD74, CNR1, CTLA4, DTX1, FLT3, ID2, IFNA2, IHH, IL2RA, IL10, IL13RA2, IDO1, INHA, IRF1, PRKAR1A, PTPN2, PTPN6, XCL1, SFTPD, SOX11, TNFSF4, TYRO3, SCGB1A1, PDE5A, CD84, PGLYRP1, TNFSF18, SOCS6 |
1369 | GO:0002064 | 0.00 | 2.14 | 34.49 | 55 | 118 | epithelial cell development | ACTA2, ARNTL, ATP2B2, ATRX, BAD, BFSP1, PRDM1, BMP4, KLF5, CDK6, CLDN3, CRYGB, DNASE1L2, EPHA2, FGFR3, GATA3, GDNF, B4GALT1, GPX1, RAPGEF1, ONECUT1, HSD17B4, ICAM1, ID1, IHH, PAX2, PDPK1, PROC, PROX1, PTPRS, RAC1, RAP1A, RARA, RARB, RHEB, SALL1, SDC1, SOX9, ST14, STC1, TNFRSF1A, CLRN1, VIM, VEZF1, IFT88, FZD7, TP63, IQGAP1, BMP15, SLC9A3R1, ONECUT2, SLC4A7, CLOCK, RAPGEF2, AKAP9 |
1370 | GO:0090066 | 0.00 | 2.14 | 79.02 | 125 | 270 | regulation of anatomical structure size | ABL1, ACTA2, ADD1, ADRA1B, AGTR1, AGTR2, AQP1, ARF1, ARHGAP4, ARHGAP5, ATP1A2, ATP2B2, AVPR1B, AVPR2, BBS4, BMPR2, CAPG, CAV3, CDK4, CDK5, CHRM1, CHRM3, CLCN3, CLCN6, CLNS1A, CPS1, CREB1, CRP, DBH, DCC, ACE, DNM2, DRD5, EDNRA, EDNRB, EFNA5, CTTN, F2R, PTK2B, FGA, GOLGA4, GPX1, GRB2, HCLS1, NRG1, HMGCR, HRH1, ICAM1, ILK, INS, ITGA1, KCNA5, KCNJ8, KCNN4, KNG1, LIMK1, MAP1B, NRCAM, NTRK3, OXTR, P2RX1, P2RX4, P2RX7, P2RY2, PAX2, PFN2, PIK3C2A, PRKCE, PRKCQ, PRKG1, PTAFR, PTEN, PTGS1, PTGS2, RAB3B, RAB5A, RAC1, RET, RNF6, CCL21, CX3CL1, SEMA3F, SHC1, SLC6A4, SLC8A1, SNTA1, SOD2, SPTA1, SPTB, SRF, CNTN2, TNR, TP73, TSC1, VAV1, VEGFA, VIL1, VIP, WAS, SEMA3B, RND2, OGT, SEMA7A, PEX11B, PEX11A, NRP1, LATS1, ITGB1BP1, SLIT2, SLC9A3R1, PICK1, ATG5, BAG4, GMFG, AATK, SEMA3E, RB1CC1, WDR1, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, ABI2, KCNMB2 |
1371 | GO:0042472 | 0.00 | 2.14 | 18.14 | 29 | 62 | inner ear morphogenesis | ALDH1A3, ATP2B2, BCR, COL2A1, COL11A1, DLX5, EPHB2, FGF3, FGF8, FGF9, FZD2, GATA3, HMX2, HPN, INSIG1, OTX1, OTX2, PAX2, PROX1, RAC1, SOX9, CLRN1, WNT1, ZIC1, FZD3, FZD6, HESX1, NRP1, SLC9A3R1 |
1372 | GO:0045740 | 0.01 | 2.14 | 13.75 | 22 | 47 | positive regulation of DNA replication | ATR, ATRX, BMP4, CDK2, CSF2, DKC1, IGF1, IGF1R, IL3, INS, JUN, KITLG, NVL, PCNA, PRKCQ, MAPK1, MAPK3, RAC1, SHC1, TNKS, AURKB, KLF4 |
1373 | GO:0050868 | 0.01 | 2.14 | 13.75 | 22 | 47 | negative regulation of T cell activation | ANXA1, BMP4, CBLB, CD74, CTLA4, DTX1, IFNA2, IHH, IL2RA, IL10, IDO1, IRF1, PRKAR1A, PTPN2, PTPN6, XCL1, SFTPD, TNFSF4, SCGB1A1, PDE5A, TNFSF18, SOCS6 |
1374 | GO:0044707 | 0.00 | 2.13 | 35.69 | 60 | 162 | single-multicellular organism process | ACTN4, ENTPD2, CD59, COL4A6, CSRP1, CTSS, DGKB, F2RL2, F10, GNA15, GNAI1, GNAI3, GP9, GRB7, HBD, HBE1, ITGAL, ITGAM, KRT14, KRT33B, KRT83, LAMP2, LCAT, OLR1, SERPINA5, PEPD, PF4V1, RAB5A, RAB27A, RAD51C, RAP2B, RBM4, SELE, SELL, SELPLG, SNCA, SNRPE, HNF1A, TNNC2, TNNI2, TRH, TUBA4A, VAV1, WAS, YWHAZ, SMC1A, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, DGKE, DGAT1, SNAP23, PROZ, HIST1H3F, DOK2, SMC3, GNA14, RASGRP2, ABCC4 |
1375 | GO:0030509 | 0.00 | 2.13 | 17.53 | 28 | 60 | BMP signaling pathway | ABL1, ACVR2B, XIAP, BMP1, BMP3, BMP8B, BMPR1A, RUNX2, DLX5, ETV2, FBN1, FGF8, GDF9, ID1, SMAD1, SMAD6, SMAD7, SMAD9, MAPK3, RYR2, T, UBE2D1, WNT1, USP9X, USP9Y, CHRD, BMP15, ZFYVE16 |
1376 | GO:0022414 | 0.00 | 2.13 | 48.80 | 78 | 172 | reproductive process | ALOX15B, ARNT, ASCL2, BMPR1A, BOK, CASP5, CASP8, CCNF, CD44, CDK2, CDX2, COL9A3, CSF2, DCN, ERCC4, ETV2, FGF8, FGF9, GATA3, GATA6, GOLGA2, GRB2, HSD17B3, HSD17B4, IDH1, IGF1R, RBPJ, IL1A, IL10, INSRR, ITGA4, LLGL2, MKI67, NUMA1, SERPINE1, SERPINB5, MAPK1, PSAP, PTGDR, PTK2, RAD21, RAD51, RAD51B, RAD51D, RBBP8, RRM1, SALL1, SDC1, SLC8A1, SMARCC1, SRD5A1, ST14, TOP2A, TOP2B, TUBG1, UBB, XRCC2, FZD5, SMC1A, ARID1A, EOMES, UTF1, AKR1C3, ADAM15, CDKL2, SOCS3, SMC3, EXO1, ZW10, BUB3, HAND1, CUL7, SMC4, ACTR3, ACTR2, RAD50, FEM1B, IRX5 |
1377 | GO:0051817 | 0.01 | 2.13 | 13.14 | 21 | 45 | modification of morphology or physiology of other organism involved in symbiotic interaction | ALB, BAD, BCL2L1, CD4, FBLN1, ITGAV, KPNA1, KPNA2, KPNA3, KPNA4, SMAD3, NUP98, SERPINB9, RANBP2, RXRA, TYMS, NUP214, AAAS, NUP155, NUP93, BCL2L11 |
1378 | GO:2001251 | 0.00 | 2.13 | 21.95 | 35 | 75 | negative regulation of chromosome organization | ATRX, BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DNMT1, DNMT3B, DUSP1, ERCC4, HMGA1, HNRNPC, JARID2, MAD2L1, PHF2, SET, SETMAR, SNCA, TAF7, TTK, UBE2D1, XRCC5, ZNF207, TNKS, CDC23, CDC16, ZW10, BUB3, TRIP12, ATG5, KDM4A, RAD50 |
1379 | GO:0030814 | 0.00 | 2.13 | 17.56 | 28 | 60 | regulation of cAMP metabolic process | ABCA1, ADCY7, ADCYAP1R1, AVPR2, CALM3, CRH, DRD3, DRD5, LPAR1, EDNRA, EDNRB, FSHR, GALR1, GCG, GHRHR, GNAI3, GNAS, NTRK2, P2RY11, PALM, PTH, RAF1, VIP, VIPR2, WFS1, AKAP6, GABBR2, AKAP12 |
1380 | GO:2000026 | 0.00 | 2.13 | 41.75 | 67 | 150 | regulation of multicellular organismal development | ACVR2B, ANGPT2, ANXA3, APOH, KLK3, AQP1, ARHGDIB, BMP1, BRCA2, C3, CBLB, KRIT1, CD3E, CLC, CCR3, COL1A1, COL4A3, CTGF, CTH, CTSH, DCN, ECM1, S1PR1, EPHA2, EMP2, F3, FOXD1, FLT1, GDF9, GPM6B, GPX1, GTF2I, HHEX, HRG, HSPB1, IL1A, IDO1, ITGA5, SMAD1, SMAD7, FOXO4, DDR2, OMD, P2RX7, SERPINE1, PRKCB, PTGIS, PTH, PTGS2, RRAS, SFRP5, SLC8A1, SP100, SPARC, SRY, TRPS1, VEGFB, ZP3, FGF23, SERPINB7, TRADD, TNFSF12, RGN, ITGB1BP1, KL, PHF14, PDCD6 |
1381 | GO:0048729 | 0.02 | 2.13 | 11.24 | 18 | 39 | tissue morphogenesis | BMPR2, ETV2, EXT2, EYA2, GNAT2, ITGA2, ITGB1, SMAD1, PRKAR1A, PTN, RPGR, SIX3, STC1, TAL1, EOMES, CHRD, SLC4A7, IRX5 |
1382 | GO:0001656 | 0.03 | 2.12 | 8.77 | 14 | 30 | metanephros development | ACAT1, AQP1, CTSH, FBN1, FGF8, FOXD1, GATA3, GPC3, HOXC11, ID2, PTCH1, SOX9, SLIT2, SPRY1 |
1383 | GO:0000723 | 0.00 | 2.12 | 16.94 | 27 | 58 | telomere maintenance | ATR, ATRX, DKC1, ERCC4, HNRNPC, PRKCQ, MAPK1, MAPK3, RAD51D, UPF1, SP100, WRN, XRCC5, HIST1H4I, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, TNKS, AURKB, DCLRE1A, PARP3, RAD50 |
1384 | GO:0043583 | 0.00 | 2.12 | 33.36 | 53 | 114 | ear development | ALDH1A3, ATP2B2, BCR, BMP4, COL2A1, COL11A1, DLX5, EPHB2, FGF3, FGF8, FGF9, FGFR3, FZD2, GABRA5, GABRB2, GATA3, HMX2, HPN, IGF1, RBPJ, INSIG1, KCNK2, KCNK3, KCNQ1, NTRK3, OTX1, OTX2, PAX2, MAPK1, MAPK3, PROX1, RAC1, RPL38, SALL1, SDC4, SOX9, SPARC, CLRN1, WNT1, ZIC1, FZD3, IFT88, FZD6, PRKRA, HESX1, LIN7A, NRP1, PHOX2B, SLC9A3R1, ATG5, SLC4A7, CXCL14, BCL2L11 |
1385 | GO:0008584 | 0.00 | 2.12 | 16.95 | 27 | 58 | male gonad development | BAX, BCL2L1, BIK, BOK, COL9A3, CTNNA1, FGF9, FSHB, FSHR, GATA3, GATA6, ING2, INHA, KIT, KITLG, PRKACG, RRM1, SRD5A1, SRY, UBB, UTF1, AKR1C3, ADAM15, SGPL1, EIF2S2, REC8, BCL2L11 |
1386 | GO:0010033 | 0.00 | 2.12 | 23.04 | 38 | 93 | response to organic substance | ACP2, ADH5, ALB, AMPD1, APOH, ATP5G3, ATRX, BCR, BDKRB1, DAGLA, CASQ1, CHAT, CNP, COL6A2, CTSG, ENSA, F2R, GOT2, FFAR1, GYS2, IGF2R, IDO1, KCNA5, NTSR1, PCNA, PROS1, PTGER1, RNF2, S100A7, S100A8, S100P, SLPI, SQLE, RNF103, FZD5, SLC10A3, USP14, GPR55 |
1387 | GO:0042059 | 0.03 | 2.12 | 8.78 | 14 | 30 | negative regulation of epidermal growth factor receptor signaling pathway | AP2B1, CBL, AP2M1, AP2S1, EPS15, GRB2, ITGA1, PTPN2, PTPRJ, RPS27A, UBB, ARHGEF7, SPRY1, STAM2 |
1388 | GO:0043507 | 0.03 | 2.12 | 8.78 | 14 | 30 | positive regulation of JUN kinase activity | EPHA4, ERCC6, PTK2B, FCER1A, MAP3K11, RPS3, SYK, TRAF2, FZD5, ARHGEF5, FZD4, FZD8, RIPK1, ZEB2 |
1389 | GO:0061178 | 0.03 | 2.12 | 8.78 | 14 | 30 | regulation of insulin secretion involved in cellular response to glucose stimulus | BAD, CRH, EFNA5, EPHA5, GCG, GPLD1, HMGCR, FOXA2, OXCT1, PRKCE, HMGN3, NRXN1, NR1D1, NR1H4 |
1390 | GO:0000724 | 0.00 | 2.12 | 20.73 | 33 | 71 | double-strand break repair via homologous recombination | ABL1, ATR, CDK2, CHEK1, ERCC4, FEN1, TONSL, PPP4C, RFC3, RFC4, RFC5, RPA2, RPA3, RPS27A, SFPQ, UBB, SUMO1, YY1, HIST1H4I, CDC45, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, HERC2, RNF8, BRE, REC8, PSMD14 |
1391 | GO:0003231 | 0.00 | 2.12 | 16.97 | 27 | 58 | cardiac ventricle development | AP2B1, PRDM1, COL11A1, DNM2, FZD2, GATA3, GATA4, NRG1, ID2, RBPJ, ISL1, KCNK2, SMAD6, SMAD7, PROX1, RXRA, RYR2, SALL1, SCN5A, SMARCD3, SOX4, SOX11, TNNC1, TNNI3, WNT11, TRIP11, HAND1 |
1392 | GO:1901605 | 0.00 | 2.11 | 37.83 | 60 | 130 | alpha-amino acid metabolic process | ADSS, ARG2, ASNS, ASS1, CKM, DHFR, DHPS, SARDH, DNMT1, DNMT3A, DNMT3B, FAU, GATM, LIPC, ODC1, P4HA1, PFAS, PSPH, PYCR1, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, SHMT2, SLC6A8, SMS, STAT5B, TYMS, P4HA2, RPL14, RPL23, EIF4A3, PTDSS1, NR1H4 |
1393 | GO:0060429 | 0.03 | 2.11 | 8.71 | 14 | 31 | epithelium development | ACAT1, AQP1, ARG2, CAT, EN1, SMAD1, SMAD6, SMAD7, SMAD9, SLC8A1, CHRD, ADAMTSL2, IFT140, ATP6AP2 |
1394 | GO:0002694 | 0.00 | 2.11 | 40.38 | 64 | 139 | regulation of leukocyte activation | ADA, ADAM8, AHR, BAD, BTK, CD3D, CD3E, CD3G, CD4, CD5, CD6, CD28, CD86, CD40, CD59, CDKN1A, CHRNB2, CLC, CD55, DHPS, DPP4, EFNB1, EFNB2, EGR3, FLOT2, FLT3LG, FYN, GATA3, GRB2, IFNG, IGF1, IGF2, IL12B, IL18, ITGAL, LMO1, PRKCQ, PTAFR, RAC1, RAG1, RARA, CCL21, SNCA, SOS2, SPTA1, STAT5B, STAT6, TRAF2, UNG, VAV1, ZP3, AP3B1, TNFSF14, TNFSF13, TNFSF9, RIPK2, IL1RL2, VNN1, AP3D1, IL1RL1, GRAP2, IL27RA, SOX13, RNF41 |
1395 | GO:0032409 | 0.00 | 2.11 | 32.19 | 51 | 110 | regulation of transporter activity | ACTN4, ATP1A2, FXYD2, BMP4, CACNB1, CACNB2, CACNB4, CALM3, CASQ2, CAV3, CRH, CRHBP, CTSS, DNM2, DRD3, PTK2B, HRC, INS, KCNJ1, KCNJ11, KCNQ1, KCNS1, KCNS2, NTSR1, PDE4B, FXYD3, PLN, PRKCE, PTAFR, PTPN3, RYR2, S100A1, SCN2B, SCN4B, SGK1, SLC9A1, SNCA, SUMO1, YWHAH, KCNAB1, RIPK1, RGN, SYNGR3, SLC9A3R1, NRXN1, GSTO1, AKAP7, AKAP6, OXSR1, SGK2, AKAP9 |
1396 | GO:0001649 | 0.00 | 2.11 | 23.32 | 37 | 80 | osteoblast differentiation | ADAR, BGLAP, BMP3, CAT, CDK6, CLTC, COL1A1, COL6A1, VCAN, DDX5, EPHA2, FGF9, HNRNPC, HSD17B4, ID1, ID2, IGFBP3, IHH, JUNB, SMAD3, MEN1, PCP4, PENK, PHB, PSMC2, PTCH1, PTK2, RPS11, SNAI1, WNT11, FGF23, SEMA7A, CHRD, DDX21, RASSF2, NR1I3, ALYREF |
1397 | GO:0021700 | 0.05 | 2.10 | 7.54 | 12 | 26 | developmental maturation | CD63, CDC20, CLCN3, PALM, PTEN, RAB3A, SYP, PICALM, AP1M1, AP3D1, NRXN3, NRXN1 |
1398 | GO:0030111 | 0.00 | 2.10 | 49.46 | 78 | 169 | regulation of Wnt signaling pathway | ABL1, ABL2, AES, XIAP, ARNTL, COL1A1, CSNK1D, CSNK2A1, CTNND1, CTNND2, DAPK3, DLX5, EDA, EMD, FGF9, FGFR3, FZD2, RAPGEF1, HHEX, HIC1, IGFBP6, RBPJ, ILK, ISL1, JUP, SMAD3, PPP1CA, PPP2R1A, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS27A, SALL1, SFRP5, SIAH2, SIX3, SMARCA4, SOX4, SOX9, SOX10, UBB, WNT1, WNT11, FZD5, FZD6, CUL3, RGS20, TNKS, LATS1, PSMF1, USP34, ZEB2, RBX1, FRAT1, HMGXB4, G3BP1, ATP6AP2, PSME3, PSMD14 |
1399 | GO:0007167 | 0.00 | 2.10 | 42.54 | 68 | 154 | enzyme linked receptor protein signaling pathway | ACVR1B, ACVR2B, ACVRL1, XIAP, BMP1, BMP3, BMP4, BMP8B, BMPR1A, CAV3, CCNC, CCNT2, CDK8, CTF1, DLX5, DNM2, E2F5, ETV2, FBN1, FOXD1, FNTA, FSHB, FUT8, GATA4, GATA6, GDF9, GPC3, GUCY2C, GUCY2F, GUCY2D, ONECUT1, HPGD, ID1, ILK, ING2, INHA, ITGB5, JUN, JUNB, LTBP2, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MEN1, SERPINE1, PPP1CA, RYR2, SOX11, SP1, T, KLF10, TRPS1, TTK, UBE2D1, VIM, USP9X, USP9Y, LTBP4, CHRD, AKAP4, BMP15, ZFYVE9, ONECUT2, GDF15, ADAMTSL2, ZFYVE16 |
1400 | GO:0048562 | 0.00 | 2.10 | 30.34 | 48 | 104 | embryonic organ morphogenesis | ALDH1A3, ATP2B2, BBS4, BCR, DLX5, EPHB2, FBN1, EFEMP1, FGF3, FGF8, FGF9, FZD2, GATA3, GATA4, HMX2, HPN, ID2, IHH, INSIG1, OTX1, OTX2, PAX2, MAPK1, MAPK3, PROX1, RAC1, RARB, RPL38, RYR2, SALL1, STIL, SIX3, SOX9, SP1, SP3, SRF, CLRN1, WNT1, ZIC1, FZD5, FZD3, ARID1A, FZD6, PRKRA, HESX1, NRP1, SLC9A3R1, HAND1 |
1401 | GO:0001736 | 0.04 | 2.10 | 8.19 | 13 | 28 | establishment of planar polarity | ABL1, ABL2, DLG3, CELSR2, GPC4, FZD2, RAC1, RYK, WNT11, FZD3, FZD6, FZD7, TP63 |
1402 | GO:0065002 | 0.04 | 2.10 | 8.19 | 13 | 28 | intracellular protein transmembrane transport | HSPA4, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PEX19, PEX5, RTN2, PEX16, TOMM20, C2CD5 |
1403 | GO:0001708 | 0.01 | 2.10 | 11.99 | 19 | 41 | cell fate specification | ASCL1, BMPR1A, ETV2, EVX1, EYA2, FOXA2, HOXC10, HOXD10, IHH, ISL1, ITGB1, NTRK3, OTX2, PAX2, SOX9, EOMES, FZD7, NRP1, OLIG2 |
1404 | GO:0046777 | 0.00 | 2.10 | 25.92 | 41 | 89 | protein autophosphorylation | ACVR1B, ALK, ATR, BCR, CAMK2A, CAMK2G, CDK5, CLK1, CLK3, CSF1R, DAPK3, EPHA4, EPHA8, EPHB1, EPHB3, FGFR3, FLT1, FLT3, FLT4, INSRR, IRAK1, JUN, KIT, MAP3K11, NTRK2, NTRK3, DDR2, PDPK1, PIM1, PRKD1, PRKX, STK10, TYRO3, VRK1, STK16, RIPK1, AURKB, STK17B, EIF2AK3, SLK, TRIM28 |
1405 | GO:0006635 | 0.02 | 2.10 | 12.00 | 19 | 41 | fatty acid beta-oxidation | ACACB, ACADM, ACADS, ACOX1, ABCD1, CNR1, CPT1B, CPT2, CRAT, ECH1, EHHADH, ETFA, ETFDH, HADHA, HSD17B4, IVD, PEX7, ABCD3, ACOX3 |
1406 | GO:1901616 | 0.02 | 2.10 | 12.00 | 19 | 41 | organic hydroxy compound catabolic process | ALDH1B1, ALDH3B2, SCARB1, COMT, CYP27B1, DBH, GK2, GPD2, INPP1, LIPC, NTSR1, PTEN, SMPD1, SORD, FGF23, CYP4F2, AKR1C3, SYNJ1, SNX17 |
1407 | GO:0048489 | 0.00 | 2.09 | 19.61 | 31 | 67 | synaptic vesicle transport | AMPH, ARF1, CACNA1A, CANX, CDK5, DNM1, DNM2, OPHN1, P2RX7, PFN2, SEPT5, RAB3A, RAB5A, RAB27A, RAP1A, ITSN1, SNAP25, SNCA, SYN1, SYT1, SYT5, AP3B2, AP3B1, STX11, SNAP23, LIN7A, SYNJ1, AP3D1, SNAP29, RIMS2, RIMS3 |
1408 | GO:0098727 | 0.00 | 2.09 | 19.61 | 31 | 67 | maintenance of cell number | ASCL2, BCL9, BMPR1A, ZFP36L2, CDX2, DDX6, EIF4E, ELAVL1, FGF4, FGFR3, IGF1, RBPJ, KIT, CNOT2, PAX2, PCM1, PROX1, RAF1, SALL1, SOX4, SOX9, STAT3, TAL1, KLF10, NR2E1, SMC1A, EOMES, FZD7, CUL4A, SMC3, KLF4 |
1409 | GO:0007050 | 0.00 | 2.09 | 21.48 | 34 | 74 | cell cycle arrest | ABL1, AK1, APBB1, APBB2, BARD1, DST, CDK6, CDKN2D, BRINP1, DUSP1, E4F1, EIF4G2, GAS1, GAS2, IFNG, IFNW1, IL12B, ILK, INHA, IRF1, SMAD3, PA2G4, PRKAA1, PRKAB2, PRKAG1, RB1, RHEB, TSC1, TSG101, CUL4A, CUL3, CUL2, CUL1, GAS7 |
1410 | GO:1901698 | 0.01 | 2.09 | 13.71 | 22 | 50 | response to nitrogen compound | ADAR, ATRX, BMP4, DDX1, DPEP1, IFIT1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IL1R1, KCNJ8, SMAD1, SMAD3, STAT6, TARBP2, TRAF2, TNFSF4, PRKRA, DDX21 |
1411 | GO:0030162 | 0.00 | 2.09 | 52.00 | 82 | 181 | regulation of proteolysis | APAF1, ARAF, BAD, BAX, BOK, CASP9, CAV3, CD14, CLU, CSNK1D, CTGF, CTSH, F2R, F3, PTK2B, FBLN1, GPLD1, HIP1, UBE2K, IFNG, SMAD3, SMAD7, MGMT, P2RX1, PCOLCE, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, RAD23B, RB1, REST, RET, RPS3, RPS27A, S100A8, S100A9, SKP1, SUMO3, TNFRSF1B, UBB, UBE3A, SUMO1, LTBP4, CUL3, CUL1, OGT, TP63, CRADD, RGN, EIF2AK3, RNF14, PPM1F, DLGAP5, RNF40, KIAA0141, TNFSF15, CASP8AP2, PDCD6, BCL2L11, PSME3, PSMD14 |
1412 | GO:0030856 | 0.05 | 2.09 | 7.58 | 12 | 26 | regulation of epithelial cell differentiation | ASCL1, GATA3, GNAQ, ID1, IFNG, KDR, REG3A, PRKX, SALL1, STAT5B, TNFRSF1A, TP63 |
1413 | GO:0030336 | 0.00 | 2.09 | 29.83 | 47 | 102 | negative regulation of cell migration | ACVRL1, ADA, AGTR2, ALOX15B, ANGPT2, APOH, ARHGDIB, BCR, BST2, KRIT1, CD63, CX3CR1, DCN, DPEP1, DPYSL3, NRG1, HRG, IGFBP3, ILK, KRT16, SMAD7, SERPINE1, SERPINF1, PFN2, PTEN, PTN, PTPRJ, PTPRR, RAP2A, RAP2B, RRAS, CCL21, CCL25, SP100, SRF, STAT3, STC1, NR2F2, VCL, WNT11, CHRD, ADAM15, KLF4, SLIT2, SLC9A3R1, PTPRU, RNF41 |
1414 | GO:0009144 | 0.00 | 2.08 | 33.07 | 52 | 113 | purine nucleoside triphosphate metabolic process | ADA, AK1, AK2, ALDOC, AMPD2, ARNT, ATP1A2, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V0A1, BAD, BPGM, TSPO, COX8A, COX15, CTNS, DLD, ENO2, GAPDH, GNAI3, GPI, GUK1, HK2, IGF1, INS, LDHC, NUDT1, OGDH, P2RX7, PFKFB4, PGAM1, PGK2, PPP2R5D, PRKAA1, PRKAG1, SDHC, SNCA, STAT3, TAZ, UQCRC1, UQCRC2, UQCRH, OGT, COX5A, SLC25A13 |
1415 | GO:0043901 | 0.00 | 2.08 | 26.05 | 41 | 89 | negative regulation of multi-organism process | ADA, ADAR, ARHGDIB, PRDM1, BST2, CD36, CTSG, FBLN1, IFI16, IFIT1, IFNA2, IFNG, IGF1, IL2RA, IL10, IL12B, ISG20, ITGAV, JUN, LTF, OAS1, OAS3, OVGP1, PCBP2, PPM1B, PROX1, REST, SEC14L1, SLPI, SP100, SRPK2, TRIM21, TARBP2, TRIM25, ZP3, TPST2, FCN3, OASL, VAPB, VAPA, TRIM28 |
1416 | GO:0000271 | 0.02 | 2.08 | 11.41 | 18 | 39 | polysaccharide biosynthetic process | CLTC, EXT2, GYS2, HAS1, HAS2, HAS3, IGF1, IGF2, INS, PHKG1, PPP1CA, PPP1R3C, PTH, RPS27A, UBB, DYRK2, NR1D1, EPM2AIP1 |
1417 | GO:0051091 | 0.01 | 2.08 | 13.94 | 22 | 48 | positive regulation of sequence-specific DNA binding transcription factor activity | ANXA3, CEBPG, EP300, EPHA5, FZD2, IL10, JUP, KIT, DDR2, PTEN, SMARCA4, SP100, SRF, TRIM21, VEGFA, WNT1, LRP8, ARHGEF5, FOSL1, FZD4, BUD31, RNF41 |
1418 | GO:1903052 | 0.00 | 2.08 | 32.49 | 51 | 111 | positive regulation of proteolysis involved in cellular protein catabolic process | CAV3, CCNB1, CDC20, CDC27, CLU, CSNK1D, PTK2B, DNAJB2, SMAD7, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, RB1, RPS27A, SKP1, SUMO3, UBB, UBE2D1, SUMO1, CUL3, CUL1, CDC23, CDC16, RGN, PSMF1, RNF14, DLGAP5, RNF40, PSME3, PSMD14 |
1419 | GO:0002520 | 0.00 | 2.07 | 126.82 | 196 | 434 | immune system development | ABL1, ABL2, ACTN1, ACVR1B, ADA, ADAM8, ADAR, ADD1, ALAS2, ANGPT1, ANXA1, ARNT, ATP6AP1, AXL, BAD, BAX, BCL3, BGLAP, PRDM1, BMI1, BMP4, BMX, BRCA2, ZFP36L2, BTK, CACNB4, CASP8, CASP9, CASP10, RUNX2, CD3D, CD4, CD8A, CD28, TNFSF8, CD40, CD74, CDK6, CEBPE, CEBPG, CHD2, CHUK, CCR1, CR2, CREB1, CRKL, CSF1R, CSF2, CTLA4, ACE, DTX1, EGR3, EPHA2, EML1, EP300, EPHB3, ETS1, ETV2, ETV6, PTK2B, FGF3, FLT3, FLT3LG, FSHB, FSHR, GATA3, GPC3, GLO1, GNAS, HCLS1, HHEX, ONECUT1, PRMT1, ID2, IFI16, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, RBPJ, IHH, IL3, IL10, IL12B, INHA, IRF1, ITGA4, ITGB1, JARID2, JUN, JUNB, KDR, KIT, LTF, SMAD3, KITLG, PIP4K2A, MAPK1, MAPK3, PRKX, PTPN2, PTPN6, PTPRZ1, PURB, RAF1, RAG1, RAG2, RARA, RB1, REST, RET, RHAG, RPL22, RPS19, RRAS, SATB1, SLC8A3, SOS2, SOX4, SP1, SP3, SPTA1, SPTB, SRF, STAT5B, STAT6, SYK, ADAM17, TAL1, TAZ, KLF10, TOP2A, TPD52, TSC1, TNFSF4, TYR, TYRO3, TYROBP, UNG, VEGFA, WNT1, XRCC5, ZNF16, FZD5, HIST1H4I, PICALM, EOMES, FZD7, FZD8, FZD9, GFI1B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, OGT, KCNAB2, PIR, AP3B1, RIPK1, TNFSF13, TNFSF9, RIPK2, IL1RL2, IL18R1, INPP4B, ARHGEF7, VNN1, SGPL1, AP3D1, PGLYRP1, TNFSF18, RNF8, CCNB2, EXO1, GPR55, KLF4, IL27RA, SOX13, VPRBP, RASSF2, ZBTB24, GAB2, BCL2L11, WASF2, RNF41, DHRS2, PRG4 |
1420 | GO:0072329 | 0.00 | 2.07 | 18.44 | 29 | 63 | monocarboxylic acid catabolic process | ABAT, ACACB, ACADM, ACADS, ACOX1, ABCD1, CNR1, CPT1B, CPT2, CRAT, ECH1, EHHADH, ETFA, ETFDH, FAAH, GOT2, HADHA, HSD17B4, IDUA, IVD, LIPE, PEX7, PEX13, ABCD3, SORD, ACOX3, CYP4F2, ALDH4A1, XYLB |
1421 | GO:1903555 | 0.01 | 2.07 | 14.62 | 23 | 50 | regulation of tumor necrosis factor superfamily cytokine production | ANGPT1, AXL, BCL3, BPI, TSPO, CD14, CD86, TNFRSF8, CD36, CLU, CYBA, GHSR, HSPB1, IL10, IL12B, ISL1, PTAFR, RARA, SLAMF1, RIPK1, RIPK2, ARHGEF2, NR1H4 |
1422 | GO:0009199 | 0.00 | 2.07 | 31.90 | 50 | 109 | ribonucleoside triphosphate metabolic process | AK1, AK2, ALDOC, AMPD2, ARNT, ATP1A2, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V0A1, BAD, BPGM, TSPO, COX8A, COX15, CTNS, DLD, ENO2, GAPDH, GNAI3, GPI, GUK1, HK2, IGF1, INS, LDHC, OGDH, P2RX7, PFKFB4, PGAM1, PGK2, PPP2R5D, PRKAA1, PRKAG1, SDHC, SNCA, STAT3, TAZ, UQCRC1, UQCRC2, UQCRH, OGT, COX5A, SLC25A13 |
1423 | GO:0033138 | 0.02 | 2.07 | 10.81 | 17 | 37 | positive regulation of peptidyl-serine phosphorylation | ANGPT1, ARAF, CD44, GCG, HCLS1, NTRK2, NTRK3, PFN2, PRKD1, RAF1, SNCA, VEGFA, BCAR3, RIPK2, LATS1, BAG4, AKAP9 |
1424 | GO:0007569 | 0.02 | 2.06 | 10.82 | 17 | 37 | cell aging | ARNTL, ATR, BGLAP, BMPR1A, BRCA2, CDKN1A, CHEK1, HMGA1, ICAM1, ID2, ILK, ING2, OPA1, SERPINE1, SRF, WRN, NUAK1 |
1425 | GO:0006353 | 0.02 | 2.06 | 10.83 | 17 | 37 | DNA-templated transcription, termination | CSTF3, ERCC3, MAZ, SRSF1, SRSF5, SRSF7, SNRPE, SNRPF, TBP, TTF1, TTF2, SRSF9, TAF1B, TAF1A, DHX38, RBM8A, ALYREF |
1426 | GO:0040014 | 0.02 | 2.06 | 10.83 | 17 | 37 | regulation of multicellular organism growth | APP, BBS4, CREB1, DRD3, GHRHR, GHSR, GNAS, IGF1, IGF2, PPIB, PRL, PTCH1, STAT3, STAT5B, VIL1, ATRN, SGPL1 |
1427 | GO:0061041 | 0.00 | 2.06 | 21.07 | 33 | 72 | regulation of wound healing | ABAT, ANXA1, ANXA5, APOH, CD36, F2, F2R, F3, F7, F12, FAP, FGA, GP1BA, HMGCR, FOXA2, HRG, KLKB1, KNG1, SMAD3, SERPINE1, REG3A, PRKCE, PRKCQ, PRKG1, PROC, PROS1, S100A9, SELP, SYK, USF1, VEGFB, VIL1, VTN |
1428 | GO:0002684 | 0.00 | 2.06 | 27.91 | 44 | 99 | positive regulation of immune system process | ACVR1B, ARNT, ATP6AP1, AXL, BAD, PRDM1, CD5, CD6, CDKN1A, CHRNB2, CSF1R, DHPS, DPP4, EFNB1, EFNB2, EGR3, ETS1, FLOT2, FLT3LG, GNAS, HCLS1, PRMT1, ID2, IGF1, IGF2, IHH, IL2RA, IL3, IL18, ITGAL, ABCB1, RAG1, RB1, SPTA1, TAL1, KLF10, ZNF16, OGT, AP3B1, TNFSF9, IL1RL2, VNN1, AP3D1, IL1RL1 |
1429 | GO:1903532 | 0.01 | 2.06 | 16.58 | 26 | 57 | positive regulation of secretion by cell | ADRBK1, ATP6AP1, CDK5, CHRNB2, FCER1A, GDNF, GLRA1, NTSR1, OXTR, PCP4, SEPT5, PTAFR, RAB3A, RAB5A, RAB27A, SDC1, SDC4, SNCA, SYT1, TACR2, TSG101, ZP3, SYT7, RAB9A, GAB2, PDCD6IP |
1430 | GO:0048738 | 0.01 | 2.05 | 13.39 | 21 | 46 | cardiac muscle tissue development | AGTR2, S1PR1, KAT2A, ITGB1, SMAD1, PLN, PRKAR1A, PTEN, RARA, RARB, SGCB, SGCD, SLC8A1, SLC9A1, SRF, TAZ, TSC1, IFT88, ARID1A, SORBS2, ATG5 |
1431 | GO:0042592 | 0.00 | 2.05 | 39.29 | 62 | 142 | homeostatic process | ADAR, ANG, AXL, TNFRSF17, KRIT1, CEBPG, CLCN6, CLNS1A, DLD, EMX1, ETV2, FEN1, GAA, GATA3, HCLS1, IFNG, INHA, KCNN4, KIT, SMAD1, PCNA, PDE4B, PRIM2, RAD51, RAD51D, RAG1, RAG2, RB1, UPF1, RFC1, RFC3, RFC4, RFC5, RPA2, RPA3, RPS19, SOS2, SP1, SP3, SP100, SPTA1, TYRO3, WRN, TUSC3, IFT88, HIST1H4I, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, IKBKG, TNFSF14, CCNB2, CHST3, RASSF2, DCLRE1A, BCL2L11, PARP3 |
1432 | GO:0046939 | 0.01 | 2.05 | 14.05 | 22 | 48 | nucleotide phosphorylation | AK1, AK2, ALDOC, ARNT, BPGM, ENO2, GAPDH, GPI, GUK1, HK2, IGF1, INS, OGDH, P2RX7, PFKFB4, PGAM1, PGK2, PPP2R5D, PRKAA1, PRKAG1, STAT3, OGT |
1433 | GO:0050776 | 0.00 | 2.05 | 19.63 | 31 | 70 | regulation of immune response | CD8A, CD37, CDH1, COL1A1, COL2A1, CXADR, ECM1, FCGR2B, ICAM1, ICAM4, IFNA5, IFNA13, IFNA17, IFNA21, IFNGR1, ITGA4, ITGAL, ITGB1, SMAD3, CD200, RAC2, SELL, SFTPD, STAT2, STXBP2, TYK2, TYROBP, SUMO1, MADCAM1, SOCS3, CD96 |
1434 | GO:0044708 | 0.00 | 2.05 | 23.58 | 37 | 82 | single-organism behavior | ABAT, ADA, AGTR2, ALB, ARCN1, BBS4, TSPO, CACNA1A, CACNB4, CHRNB4, CLCN3, CNP, DNM1, EPHA4, ETV1, GDNF, GHRHR, GHSR, GLRA1, GLRB, FOXA2, HOXD9, HOXD10, KCNJ10, P2RX3, PRKCE, SCN1A, SCN8A, SNCA, SRD5A1, TBCE, TRH, TSC1, TRPV1, ZIC1, PER3, PUM1 |
1435 | GO:0010604 | 0.00 | 2.05 | 178.92 | 274 | 648 | positive regulation of macromolecule metabolic process | ABL1, ABL2, ACVR2B, ADCY1, ADCY7, ADRA1B, AGTR1, ANG, ANGPT1, APAF1, BIRC3, XIAP, ARAF, ATP6AP1, ATR, BAD, BARD1, BAX, BMI1, BMP1, BMP8B, BOK, ZFP36L2, CALM3, CAMK2G, CASP8, CASP9, CAV3, CBLB, CD4, CD14, TNFRSF8, CD36, CD63, CD74, CDC6, CDC20, CDC27, CDK5, CDKN1A, CENPE, CCR1, COL4A3, CR1, CRKL, CSF1R, CSF2RB, CSNK1D, CSNK2A1, CSPG4, CTF1, ACE, DKC1, DUSP5, DUSP7, DUSP9, LPAR1, EDNRA, EDNRB, EFNA1, EFNA5, EMP2, EPHA4, EPHA8, EPOR, F2, F3, FCER1A, FCER2, FGA, FGF3, FGF6, FGFR3, FLT1, FLT3, FLT3LG, FLT4, FNTA, FPR1, FSHR, FYN, GDF9, GPC3, GNG3, GOLGA2, GPLD1, GRB2, RAPGEF1, GRIN2A, GRM1, HIST1H1B, HAS2, HIP1, UBE2K, HMGCR, HPX, PRMT1, DNAJB2, HSPB1, HTR2C, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGF1R, IGFBP3, IL2RA, IL2RB, IL2RG, IL3, IL12B, IL13, INHA, ITGA1, ITGA5, ITGB1, JARID2, KDR, KISS1, MARK3, KITLG, MGMT, ATXN3, MAP3K11, NVL, OAZ1, OAZ2, P2RX1, PCNA, PCOLCE, PDPK1, PFN2, PIM1, PPP1R7, PPP5C, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PSAP, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMB1, PSMB2, PSMB4, PSMB7, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD11, PTK2, PTPRA, PTPRZ1, RAB1A, RAC1, RAD51, RAP1A, RAP2A, RAP2B, RASA2, UPF1, RYK, S100A7, CCL21, CCL22, CCL25, XCL1, CX3CL1, SDC4, SELE, SETMAR, SHC1, STIL, SKP1, SKP2, SLAMF1, SMPD1, SUMO3, SNCA, SORL1, SPTA1, SPTB, STK10, SUPV3L1, XCL2, SYK, ADAM17, NR2F1, TNFRSF1B, TPD52L1, TTK, TNFSF4, UBE2D1, UBE2L3, SUMO1, UNG, VEGFB, VIP, VTN, WFS1, AIMP2, CDK2AP1, BCAR3, DYRK2, CUL3, CUL1, SEMA7A, CDC14B, MADD, PDE5A, PEA15, CDC23, SERPINB7, EED, CRADD, TNFSF13, TNFSF12, TNFSF10, TNFRSF18, TNFRSF10B, TNFRSF10A, IQGAP1, NRP1, CDC16, RNF8, UNC119, RGN, LATS1, BMP15, AURKB, VAPB, GPR55, KL, PICK1, AKAP6, PSMF1, GDF15, BAG4, NRG2, SEC22B, GTPBP1, BRE, TRAF4, RAPGEF2, SLK, RASSF2, ATG13, DLGAP5, RNF40, RB1CC1, EPM2AIP1, OXSR1, TNFSF15, RBX1, CASP8AP2, HDAC6, PDCD6, BCL2L11, PARP3, RAD50, AKAP9, RASA4, PSME3, PSMD14, RAMP3 |
1436 | GO:0050727 | 0.01 | 2.05 | 12.76 | 20 | 44 | regulation of inflammatory response | ANXA1, BIRC3, XIAP, C7, CASP5, CD59, CR1, CD55, EDNRB, IL1R1, CFP, PHB, PROS1, PSMA6, SELE, SCGB1A1, VTN, SEMA7A, IL1RL2, NR1D2 |
1437 | GO:1904589 | 0.00 | 2.05 | 26.92 | 42 | 92 | regulation of protein import | AGTR2, ANGPT1, BCL3, BMP4, BMPR1A, CD36, CDH1, CDKN1A, EDA, EMD, GNAQ, HCLS1, IGF1, IL10, IL12B, IL18, JUP, KPNA1, IPO5, SMAD3, TONSL, PRDX1, PPM1B, PRKCQ, PTGS2, SFRP5, SLC9A1, TRIP6, ZIC1, ARHGEF5, AKAP1, FZD7, DYRK2, RGS20, TNFSF14, IL18R1, SLC9A3R1, AKAP6, CABP1, LITAF, TRIM28, NUTF2 |
1438 | GO:0019058 | 0.00 | 2.04 | 41.71 | 65 | 144 | viral life cycle | CD28, DDB1, DDX3X, DDX5, DDX6, EP300, ERCC3, FAU, NR5A2, HPN, KPNA2, KPNA4, NUP98, CHMP1A, PCSK5, PPIB, PPID, RAB1A, RANBP2, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, SMARCA4, SP1, SSRP1, STAU1, TARBP2, TOP2A, USF1, NUP214, AAAS, RPL14, CTDP1, RPL23, ATG5, NUP155, NUP93, USP6NL, PDCD6IP |
1439 | GO:0051271 | 0.00 | 2.04 | 39.22 | 61 | 134 | negative regulation of cellular component movement | ACTN4, ACTN1, ACVRL1, ADA, AGTR2, ALOX15B, ANGPT2, APOH, ARHGAP4, ARHGDIB, BCR, BST2, KRIT1, CD63, CTNNA1, CX3CR1, DCN, DPEP1, DPYSL3, FBLN1, GATA3, HAS1, NRG1, HRG, IGFBP3, ILK, KRT16, SMAD7, SERPINE1, SERPINF1, PFN2, PTEN, PTN, PTPRJ, PTPRR, RAP2A, RAP2B, RRAS, CCL21, CCL25, SEMA3F, SP100, SRF, STAT3, STC1, NR2F2, VCL, WAS, WNT11, SEMA3B, CHRD, ADAM15, NRP1, RGN, ITGB1BP1, KLF4, SLIT2, SLC9A3R1, SEMA3E, PTPRU, RNF41 |
1440 | GO:0051348 | 0.00 | 2.04 | 62.63 | 97 | 214 | negative regulation of transferase activity | ABL1, ADAR, BMP4, BUB1, BUB1B, CAV3, CCNB1, CDC20, CDC27, CDKN1A, CDKN2D, CENPF, CHAD, DCN, DUSP1, DUSP5, DUSP7, DUSP9, EIF4A2, GNAQ, GP1BA, HHEX, HMGCR, FOXA2, HSPB1, IGF1R, ILK, LIMK1, MAD2L1, SMAD7, MEN1, PCP4, PDPK1, PPP2R1A, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, DNAJC3, PRPSAP1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTPN2, PTPN6, PTPRJ, RANBP2, RB1, RPS27A, SMPD1, SORL1, TAF7, TARBP2, NR2F2, TP73, TTK, UBB, UBE2D1, ZNF207, CUL3, CDC23, CDC16, SOCS3, RGN, LATS1, ZW10, BUB3, ITGB1BP1, SOCS6, PSMF1, BAG5, GMFG, PPM1F, RUBCN, PSME3, PSMD14, SPRY1 |
1441 | GO:1904666 | 0.03 | 2.04 | 10.24 | 16 | 35 | regulation of ubiquitin protein ligase activity | BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, DUSP1, MAD2L1, PTEN, TTK, UBE2D1, ZNF207, CDC23, CDC16, ZW10, BUB3 |
1442 | GO:0005996 | 0.00 | 2.04 | 31.45 | 49 | 108 | monosaccharide metabolic process | ACACB, ADRA1B, BAD, CACNA1A, CALM3, CYB5A, CYB5R3, FUT6, FUT8, GAA, GALE, GALK2, GCGR, B4GALT1, GPLD1, GYS2, HK2, FOXA2, ONECUT1, IGF1, IGF2, IGFBP3, INPPL1, KCNJ11, MAN2B1, OAS1, PDK4, PFKFB4, PHKA2, PHKB, PHKG1, PPP1CA, PPP1R3C, PPP2R5D, PRKAA1, PRKCE, PTH, PYGB, PYGM, RPE, RPS27A, SLC2A3, UBB, UGT2B7, UGT8, USF1, DYRK2, EPM2AIP1, XYLB |
1443 | GO:0019048 | 0.01 | 2.04 | 13.46 | 21 | 46 | modulation by virus of host morphology or physiology | BAD, BCL2L1, CD4, FBLN1, KPNA1, KPNA2, KPNA3, KPNA4, SMAD3, NTRK3, NUP98, RANBP2, RXRA, TYMS, NUP214, AAAS, VAPB, VAPA, NUP155, NUP93, BCL2L11 |
1444 | GO:0061448 | 0.00 | 2.04 | 32.17 | 50 | 110 | connective tissue development | ACAT1, ACVRL1, BBS4, BMP1, BMP3, BMP8B, BMPR1A, BMPR2, RUNX2, CD44, COL1A1, COL2A1, COL9A1, COL10A1, COL11A1, COMP, CTGF, EFEMP1, FGF4, FGF6, FGF9, FGFR3, FOXD1, GNAS, GPLD1, HMGCS2, FOXA2, ID2, IGF1, IHH, SMAD1, SMAD3, SMAD9, OXCT1, MAPK3, RARA, RARB, SNAI1, SOX5, SOX9, SRF, STC1, TRPS1, TYMS, UBB, WNT11, DYRK1B, HAND1, EIF2AK3, ZNF516 |
1445 | GO:0046034 | 0.00 | 2.03 | 19.26 | 30 | 66 | ATP metabolic process | AK1, AK2, AMPD2, ATP1A2, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V0A1, BAD, TSPO, COX8A, COX15, CTNS, DLD, GUK1, LDHC, SDHC, SNCA, TAZ, UQCRC1, UQCRC2, UQCRH, COX5A, SLC25A13 |
1446 | GO:0001817 | 0.00 | 2.03 | 26.30 | 41 | 91 | regulation of cytokine production | BIRC3, ARNT, ATF4, C3, CD6, CD40, CHUK, CREB1, CSF2, DDX3X, ELF1, EP300, FLT4, ACKR1, GATA4, IFI16, IL12RB2, IL18, IRAK1, IRF5, SMAD3, P2RY2, SERPINE1, PTGS2, SEC14L1, TRIM21, STAT6, ADAM17, XRCC5, ZP3, IKBKG, SERPINB7, TNFSF9, IL1RL2, IL18R1, IQGAP1, EIF2AK3, IL27RA, LITAF, PUM1, ATP6AP2 |
1447 | GO:0010941 | 0.00 | 2.03 | 27.92 | 44 | 102 | regulation of cell death | ACTN4, ACTN1, ALK, ALX3, BMP1, BMP3, BMP8B, BTK, CASP5, CASP10, CD3E, CD3G, DBH, DCC, EPHB1, ETS1, FLT3, GAS1, GDF9, GRID2, TNFRSF9, ING1, INHA, JUNB, JUND, PHB, SKP2, SP100, STK10, ADAM17, TNFRSF1A, TNFRSF1B, TRAF1, TSC1, WRN, BMP15, GDF15, BCAR1, TRAF4, SLK, KIAA0141, OXSR1, SGK2, FEM1B |
1448 | GO:0006082 | 0.00 | 2.03 | 156.41 | 238 | 538 | organic acid metabolic process | ACADS, ACAT1, ACO2, ACOX1, ACY1, ADSS, ALB, ABCD1, ALDOC, ANGPT1, ARG1, ARG2, ARNT, ATF4, ALDH7A1, AUH, BCKDHA, BPGM, BSG, C3, DAGLA, CACNA1A, CKM, CNR1, COMT, CPT1B, CPT2, CRAT, SLC25A10, CTNS, CYB5A, CYP1A2, CYP2A6, CYP2A13, CYP2F1, DAO, DARS, DBT, DCT, CYB5R3, DLD, SARDH, DNMT1, DNMT3A, DNMT3B, DPEP1, ECH1, EHHADH, ENO2, EPRS, ETFA, ETFDH, EXT2, EXTL1, EXTL3, FAAH, FAU, GPC4, GPC5, NR5A2, G6PC, GALNS, GAPDH, GARS, GATA3, B4GALT1, GHSR, GPC3, GLDC, GLO1, GPC1, GPI, GPX1, GSS, GSTZ1, HADHA, HARS, HEXA, HEXB, HK2, HLCS, HNMT, HPD, HPN, IDH1, IDH3A, IDS, IDUA, IGF1, INS, IVD, LIPA, LIPE, MDH2, OAZ1, OAZ2, ODC1, OMD, OGDH, P2RX7, P4HA1, PAM, PCK1, PEPD, PEX7, PEX13, PFAS, PFKFB4, PGAM1, PGD, PGK2, PPP2R5D, PRKAR2B, PRKCE, MAPK3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, QARS, QDPR, RENBP, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, RXRA, SDC1, SDC4, SDHA, SDHB, SDHC, SDHD, SLC2A3, SLC6A6, SLC6A8, SLC7A4, SLC10A1, SLC34A1, SLCO1A2, SLC22A5, SMS, SNCA, SORD, SREBF1, STAT3, STAT5B, SULT1E1, SULT1A3, SULT1C2, SULT2B1, SUOX, TAT, TNFRSF1A, TYMS, TYR, UGT2B7, UGT8, AIMP2, SLC25A16, PDHX, SLC7A5, ACOX3, OGT, DDO, CYP4F2, B4GALT4, B4GALT3, ABCC3, SUCLG1, VNN2, VNN1, SGPL1, SLC5A6, P4HA2, RPL14, PAPSS1, B4GALT6, RPL23, GRHPR, EIF2AK3, CHST3, PSMF1, MINPP1, SDC3, EIF4A3, PTDSS1, SPOCK2, XYLB, HS3ST3B1, GNE, SLC25A15, PSME3, PSMD14 |
1449 | GO:0043255 | 0.03 | 2.02 | 9.65 | 15 | 33 | regulation of carbohydrate biosynthetic process | CLTC, GCG, KAT2A, HAS2, IGF1, IGF2, INS, PPP1CA, PTH, PTPN2, RANBP2, DYRK2, OGT, NR1D1, EPM2AIP1 |
1450 | GO:0014706 | 0.00 | 2.02 | 20.58 | 32 | 71 | striated muscle tissue development | ATF3, BCL9, KLF5, CASQ1, CDK5, CENPF, COL19A1, CSF1R, DCN, DDX5, TSC22D3, EGR2, EMD, EP300, EYA2, GPX1, HLF, HOXD9, HOXD10, SMAD3, MEOX2, RB1, RYR1, SOX11, NR2F2, KCNAB1, EOMES, SAP30, PHOX2B, COPS2, GTF3C5, NR1D2 |
1451 | GO:1990748 | 0.02 | 2.02 | 12.88 | 20 | 44 | cellular detoxification | ALB, CAT, CD36, DHFR, GPX1, GPX2, GSTZ1, HBA1, HBA2, HP, PRDX1, PTGS1, PTGS2, S100A9, SEPW1, SOD2, SOD3, PRDX2, RGN, GSTO1 |
1452 | GO:0050770 | 0.00 | 2.02 | 25.17 | 39 | 86 | regulation of axonogenesis | ABL1, ARHGAP4, BMPR2, CACNA1A, CDK5, CHN1, DCC, DNM2, EFNA1, EFNA5, CTTN, EPHA4, EPHB3, GDI1, GOLGA4, NRG1, ILK, LIMK1, MAP1B, NRCAM, NTRK2, NTRK3, PTEN, PTK2, RET, RNF6, SEMA3F, SRF, CNTN2, TNR, VEGFA, SEMA3B, RND2, SEMA7A, NRP1, ARHGEF1, SLIT2, AATK, SEMA3E |
1453 | GO:0010803 | 0.04 | 2.02 | 9.66 | 15 | 33 | regulation of tumor necrosis factor-mediated signaling pathway | BIRC3, CASP8, CHUK, PTPN2, RPS27A, SYK, TNFRSF1A, TRAF1, TRAF2, UBB, IKBKG, MADD, TRADD, RIPK1, TAX1BP1 |
1454 | GO:0050672 | 0.04 | 2.02 | 9.66 | 15 | 33 | negative regulation of lymphocyte proliferation | PRDM1, BMP4, CBLB, CTLA4, IHH, IL2RA, IL10, IDO1, PRKAR1A, PTPN6, XCL1, SFTPD, SOX11, SCGB1A1, PDE5A |
1455 | GO:0001932 | 0.00 | 2.02 | 80.28 | 124 | 284 | regulation of protein phosphorylation | ABL2, ACVR1B, ACVRL1, ADRA1B, ARR3, ATF3, ATP6AP1, BDKRB1, BMP1, BMP3, BMP8B, BMPR1A, BMPR2, C3, CCNB1, CD3E, CD36, CD44, CCR1, CRH, CRYBA1, CSNK1D, CTF1, CTGF, EDNRA, EDNRB, EPHA2, EPHA8, EPHB1, EPOR, F2, FBLN1, FGA, FLT3LG, FLT4, FSHR, GDF9, HCLS1, UBE2K, HPX, HRC, HRG, PRMT1, HTR2C, ICAM1, ID1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGFBP3, IL1A, IL13, IL18, INHA, ISL1, ITGA5, ITGB1, JUN, KDR, KISS1, SMAD3, SMAD6, SMAD7, NTRK2, PRDX1, PFN2, PHB, PRKCE, PRKD1, PSAP, PTPRR, PTPRZ1, RAC1, RAD51, RAP2A, RET, RRAS, RYK, S100A7, CCL22, CCL25, XCL1, CX3CL1, SLAMF1, SOX9, SPINK1, STYX, XCL2, TNFRSF1A, TNFRSF1B, TTK, VEGFB, VTN, WNT1, CDK2AP1, FZD7, BCAR3, OGT, SEMA7A, TNFRSF18, NRP1, RPS6KA4, TNFSF18, ARHGEF2, BMP15, RPS6KA5, GPR55, KLF4, SLIT2, EIF2AK3, GDF15, BAG4, RB1CC1, RANBP9, CTDSP2, RAD50, ATP6AP2, RNF41, CTDSPL |
1456 | GO:0042060 | 0.01 | 2.02 | 17.31 | 27 | 61 | wound healing | ACVRL1, AQP1, BCL9, BMP4, CAV3, CCNB1, SCARB1, DCN, DRD5, ELK3, FGF7, NRG1, IL1A, INS, ITGA9, P2RY2, PTPN12, S100A8, SCNN1B, SDC1, SDC4, SPRR3, ADAM17, DYSF, FZD7, ADAM15, SYT7 |
1457 | GO:0006721 | 0.01 | 2.01 | 15.49 | 24 | 53 | terpenoid metabolic process | ABCA4, ADH5, ALDH3A2, OPN1SW, AKR1C4, CLPS, CRH, CYP1A2, CYP3A4, GPC4, GPC5, OPN1MW, GPC3, GPC1, RBP2, OPN1LW, RLBP1, SDC1, SDC4, SLC12A1, SRD5A1, LRP8, DGAT1, SDC3 |
1458 | GO:0007517 | 0.01 | 2.01 | 17.41 | 27 | 60 | muscle organ development | AEBP1, CHD2, COL6A3, COL11A1, CRYAB, CTF1, S1PR1, EGR3, ETV1, FZD2, IGF1, ISL1, ITGA7, SMAD7, FOXO4, PROX1, RXRA, RYR2, SCN8A, SGCA, SGCB, SGCD, SMTN, TNNC1, TNNI3, HAND1, FAM65B |
1459 | GO:0060538 | 0.00 | 2.01 | 24.58 | 38 | 84 | skeletal muscle organ development | ARNTL, ASS1, ATF3, BCL9, KLF5, CASQ1, CDK5, COL19A1, CSF1R, DCN, DDX5, TSC22D3, EGR2, EMD, EP300, GPC1, GPX1, HLF, HMGCR, HOXD9, HOXD10, MEOX2, PAX3, PRKAA1, RB1, RPS6KB1, RYR1, SOX11, TAZ, NR2F2, KCNAB1, EOMES, SAP30, PHOX2B, USP2, COPS2, GTF3C5, NR1D2 |
1460 | GO:0061351 | 0.04 | 2.01 | 9.02 | 14 | 31 | neural precursor cell proliferation | RERE, DBN1, EMX1, EPHB1, RAPGEF1, ID2, ILK, PTPRZ1, RYK, SALL1, SLC6A4, WNT1, IFT88, FZD6 |
1461 | GO:1903707 | 0.00 | 2.01 | 21.36 | 33 | 73 | negative regulation of hemopoiesis | ANXA1, BMP4, CD74, CDK6, CTLA4, DTX1, PTK2B, FLT3, PRMT1, ID2, IFNA2, IHH, INHA, IRF1, LTF, PTPN2, RARA, STAT5B, TNFSF4, HIST1H4I, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, INPP4B, PGLYRP1, TNFSF18, GPR55 |
1462 | GO:0006334 | 0.01 | 2.01 | 14.86 | 23 | 51 | nucleosome assembly | ATRX, CENPA, CENPI, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, HIST1H2BB, H3F3B, HIST1H1A, SET, SOX9, TSPY1, HIST1H2BL, HIST1H2BN, HIST1H2BM, HIST1H2BF, HIST1H2BH, HIST1H2BO, HIST2H2BE, SMARCA5, RUVBL1 |
1463 | GO:0031577 | 0.02 | 2.00 | 12.29 | 19 | 42 | spindle checkpoint | BIRC5, BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DUSP1, MAD2L1, TTK, UBE2D1, ZNF207, CDC23, CDC16, ZW10, BUB3, AURKB |
1464 | GO:0034637 | 0.02 | 2.00 | 12.29 | 19 | 42 | cellular carbohydrate biosynthetic process | EXT2, B4GALT1, GYS2, HAS1, HAS2, HAS3, IGF1, IGF2, INS, PCK1, PHKG1, PPP1CA, PPP1R3C, PTH, RPS27A, UBB, DYRK2, NR1D1, EPM2AIP1 |
1465 | GO:0009132 | 0.01 | 2.00 | 18.14 | 28 | 62 | nucleoside diphosphate metabolic process | AK1, AK2, ALDOC, ARNT, BAD, BPGM, ENTPD2, DLG2, DLG3, ENO2, GAPDH, GPI, GUK1, HK2, IGF1, INS, OGDH, P2RX7, PFKFB4, PGAM1, PGK2, PPP2R5D, PRKAA1, PRKAG1, RRM2, STAT3, OGT, ENTPD4 |
1466 | GO:1902680 | 0.00 | 2.00 | 218.91 | 327 | 748 | positive regulation of RNA biosynthetic process | ACVR1B, ACVRL1, ADAM8, AGTR2, AHR, ALK, ANXA3, APBB1, APP, ARF4, PHOX2A, ARNT, ARNTL, ASCL1, ATF3, ATF4, RERE, ATRX, BACH1, BCL3, BCL9, BMP3, BMP4, BMPR1A, BMPR2, BRCA2, BRDT, KLF5, BTK, CAMK2A, CAT, RUNX2, CCNC, CCNE1, CCNT2, CD3D, CD28, CD86, TNFSF8, CD40, CDH1, CDK2, CDK8, CDX2, CEBPE, CEBPG, CHEK1, CHUK, CLU, COL1A1, CREB1, CRX, CTH, DBP, DCN, DDX3X, DDX5, DLX5, DNM2, DRD3, ARID3A, E2F5, EBF1, EDA, S1PR1, EGR2, ELF1, ELF3, ELK1, ELK3, EN1, EP300, EPHA5, ERCC3, ERCC6, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV4, ETV5, ETV6, EVX1, EZH1, F2R, FGF4, FGF7, FSHB, NR5A2, FZD2, GALR1, GATA3, GATA4, GATA6, GCG, KAT2A, GDNF, HAS3, HCLS1, HEXB, HGF, NRG1, HHEX, HMGN1, HMGA1, NR4A1, FOXA2, HNF4G, ONECUT1, HOXC11, HOXD8, HOXD9, HOXD10, HPN, HSF4, ICAM1, ID2, IFI16, IFNA2, IFNG, IGF1, IGF2, RBPJ, IHH, IL1A, IL10, ILK, ING2, INS, INSIG1, IRAK1, ITGA6, IRAK2, IRF1, IRF5, ISL1, JUN, JUNB, JUND, JUP, KIT, LMO1, LTF, SMAD1, SMAD3, SMAD7, SMAD9, MEN1, MEOX2, CIITA, AFF1, FOXO4, PPP1R12A, NRF1, YBX1, DDR2, OTX1, OTX2, SERPINE1, PAX2, PAX3, PAX9, PCK1, PGR, PHB, PHF2, PRKCB, PRKCI, PRKD1, PRKCQ, MAPK1, MAPK3, PROX1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD9, PTCH1, PTEN, PTH, RAD21, RAF1, RAN, RARA, RARB, RB1, REST, RET, RFX3, RFX4, RFXAP, RLF, RNF6, RPS3, RPS6KA1, RPS6KA3, RPS27A, RXRA, RXRG, S100A8, S100A9, S100A12, SALL1, ATXN7, SIX3, SLC9A1, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCD3, SNAI1, SOX4, SOX5, SOX9, SOX10, SOX11, SP1, SP3, SP100, SREBF1, SRF, SRY, TRIM21, SSRP1, STAT3, STAT4, STAT5B, STAT6, T, TAF7, TAL1, TBL1X, TBP, HNF1A, NR2F2, NR2E1, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C2, TRAF1, TRAF2, TRPS1, UBB, UBE2V1, UBE3A, NR1H2, USF1, VDR, VEGFA, WNT1, WNT11, YY1, YWHAH, ZIC1, CNBP, ZSCAN21, TRIM25, ZNF148, ZBTB17, ZP3, ZXDA, LRP8, FZD5, MAFK, ARHGEF5, FOSL1, FGF23, NRIP1, ARID1A, PICALM, EOMES, FZD4, FZD7, FZD8, UTF1, OGT, IKBKG, STK16, KLF7, TP63, TNKS, TRADD, RIPK1, RIPK2, BUD31, PHOX2B, FUBP3, RPS6KA4, TNFSF18, BAZ1B, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, CCPG1, RPS6KA5, ITGB1BP1, KLF4, HMGN3, TRIP4, HAND1, EIF2AK3, FHL5, ONECUT2, NR1D1, CLOCK, CREB5, RNF14, ZNF516, ARHGEF11, ZEB2, RNF10, NR1I3, NR1H4, NR1D2, NR2E3, YAF2, TRIM28, ALYREF, RNF41 |
1467 | GO:2000242 | 0.04 | 2.00 | 9.07 | 14 | 31 | negative regulation of reproductive process | ADA, ARHGDIB, BMP4, DUSP1, IGF1, OVGP1, OVOL1, SERPINF1, PRKACB, PRKAR1A, RPS6KA2, SNAI1, ZP3, TPST2 |
1468 | GO:0002366 | 0.00 | 2.00 | 22.71 | 35 | 78 | leukocyte activation involved in immune response | ABL1, ADA, ANXA1, BCL3, CD28, CD86, CD40, PTK2B, GATA3, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IL10, IL12B, ITGAL, RAB27A, RARA, STAT6, TSC1, TNFSF4, UNG, EOMES, TNFSF13, RIPK2, IL18R1, PGLYRP1, TNFSF18, RNF8, EXO1, IL27RA |
1469 | GO:0009891 | 0.00 | 2.00 | 278.90 | 412 | 953 | positive regulation of biosynthetic process | ABCA1, ACVR1B, ACVRL1, ADAM8, ADCY7, ADCYAP1R1, AGTR2, AHR, ALK, ANXA1, ANXA3, APBB1, APP, ARF4, PHOX2A, ARNT, ARNTL, ASCL1, ASIP, ASS1, ATF3, ATF4, RERE, ATR, ATRX, AVPR2, BACH1, BCL3, BCL9, BMP3, BMP4, BMPR1A, BMPR2, BRCA2, BRDT, KLF5, BTK, CALM3, CAMK2A, CAT, RUNX2, CCNC, CCNE1, CCNT2, CD3D, CD3E, CD4, CD28, CD86, TNFRSF8, TNFSF8, SCARB1, CD40, CDH1, CDK2, CDK4, CDK8, CDX2, CEBPE, CEBPG, CHEK1, CHUK, CIRBP, CLCN3, CLU, COL1A1, CREB1, CRH, CRX, CSF2, CTGF, CTH, CYBA, DAZ1, DBP, DCN, DDX3X, DDX5, DKC1, DLX5, DNM2, DRD3, DRD5, ARID3A, E2F5, EBF1, EDA, S1PR1, EDNRA, EGR2, EIF5A, ELAVL1, ELF1, ELF3, ELK1, ELK3, EN1, EP300, EPHA5, ERCC3, ERCC6, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV4, ETV5, ETV6, EVX1, EZH1, F2, F2R, PTK2B, FCER1A, FCER2, FGF4, FGF7, FSHB, FSHR, NR5A2, FZD2, GALR1, GATA3, GATA4, GATA6, GCG, KAT2A, GDNF, GHRHR, GNAS, GOLGA2, GPLD1, GUCA1A, GUCA2A, GUCA2B, HAS2, HAS3, HCLS1, HEXB, HGF, NRG1, HHEX, HMGN1, HMGA1, NR4A1, FOXA2, HNF4G, ONECUT1, HOXC11, HOXD8, HOXD9, HOXD10, HPN, HRH1, PRMT1, HSF4, HSPB1, HTR2C, ICAM1, ID2, IFI16, IFNA2, IFNG, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL3, IL10, IL12B, ILK, ING2, INS, INSIG1, IRAK1, ITGA6, IRAK2, IRF1, IRF5, ISL1, ITGA2, JUN, JUNB, JUND, JUP, KDR, KIT, LMO1, LTF, SMAD1, SMAD3, SMAD7, SMAD9, MEN1, MEOX2, KITLG, CIITA, AFF1, FOXO4, PPP1R12A, NRF1, YBX1, NTRK2, DDR2, NTSR1, NVL, OTX1, OTX2, P2RX4, P2RY11, SERPINE1, PAX2, PAX3, PAX9, PCK1, PCNA, PGR, PHB, PHF2, PRKAA1, PRKCB, PRKCI, PRKD1, PRKCQ, MAPK1, MAPK3, DNAJC3, PROX1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD9, PTAFR, PTCH1, PTEN, PTH, PTGS2, PTPN2, RAB27A, RAC1, RAD21, RAF1, RAN, RARA, RARB, RB1, RCVRN, REST, RET, RFX3, RFX4, RFXAP, RLF, RNF6, RPS3, RPS6KA1, RPS6KA3, RPS6KB1, RPS6KB2, RPS27A, RXRA, RXRG, S100A8, S100A9, S100A12, SALL1, ATXN7, CCL21, SHC1, SIX3, SLC9A1, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCD3, SNAI1, SNCA, SOX4, SOX5, SOX9, SOX10, SOX11, SP1, SP3, SP100, SREBF1, SRF, SRY, TRIM21, SSRP1, STAT3, STAT4, STAT5B, STAT6, SYK, T, TAF7, TAL1, TARBP2, TBL1X, TBP, HNF1A, NR2F1, NR2F2, NR2E1, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C2, TRAF1, TRAF2, TRPS1, UBB, UBE2V1, UBE3A, NR1H2, USF1, VDR, VEGFA, VIP, VIPR2, TRPV1, WFS1, WNT1, WNT11, YY1, YWHAH, ZIC1, CNBP, ZSCAN21, TRIM25, ZNF148, ZBTB17, ZP3, ZXDA, LRP8, FZD5, MAFK, ARHGEF5, FOSL1, FGF23, NRIP1, ARID1A, PICALM, EOMES, FZD4, FZD7, FZD8, UTF1, NSMAF, DYRK2, OGT, IKBKG, STK16, KLF7, TP63, TNKS, SERPINB7, TRADD, RIPK1, RIPK2, BUD31, PHOX2B, FUBP3, RPS6KA4, TNFSF18, BAZ1B, RGN, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, AURKB, CCPG1, RPS6KA5, ITGB1BP1, KLF4, HMGN3, TRIP4, HAND1, EIF2AK3, FHL5, ONECUT2, NR1D1, CLOCK, CREB5, AKAP12, RNF14, GUCA1C, ZNF516, EIF4A3, ARHGEF11, ZEB2, EPM2AIP1, RNF10, NR1I3, NR1H4, NR1D2, NR2E3, HDAC6, YAF2, TRIM28, ALYREF, RNF41 |
1470 | GO:0030307 | 0.01 | 1.99 | 17.52 | 27 | 60 | positive regulation of cell growth | ADAM10, CSNK2A1, CYBA, DDX3X, EFNA5, EXTL3, F2, PTK2B, HIST1H1B, H3F3B, HPN, IGF1, INS, EXOSC9, RPS6KA1, RPS6KA3, S100A8, S100A9, SGK1, SLC9A1, SUPV3L1, SYT1, SYT4, ADAM17, RND2, AKAP6, RIMS2 |
1471 | GO:0043123 | 0.00 | 1.99 | 26.01 | 40 | 89 | positive regulation of I-kappaB kinase/NF-kappaB signaling | ABL1, ABL2, BIRC3, BST2, CASP8, CASP10, CD36, CD40, CHUK, CTH, ECM1, LPAR1, F2R, FYN, IL1A, IRAK1, LTF, PPP5C, PRKCB, PRKCE, PRKD1, RPS27A, S100A4, S100A12, S100A13, CCL21, SLC20A1, TNFRSF1A, TRAF2, UBB, UBE2V1, TRIM25, IKBKG, TRADD, RIPK1, TNFSF10, RIPK2, TNFRSF10B, VAPA, LITAF |
1472 | GO:0019752 | 0.00 | 1.99 | 134.16 | 203 | 463 | carboxylic acid metabolic process | ACY1, ADSS, ALB, ALDH1A3, ALDOC, ALOX15B, ANXA1, ARG2, ARNT, ASNS, ATF4, BHMT, BPGM, BSG, C3, DAGLA, CACNA1A, CBR1, CD74, AKR1C4, CKM, COMT, CPS1, VCAN, CSPG4, CTNS, CYB5A, CYP1A2, CYP2A6, CYP2A13, CYP2F1, CYP8B1, DARS, DCN, DCT, DHFR, DHPS, CYB5R3, SARDH, DNMT1, DNMT3A, DNMT3B, DPEP1, ENO2, EPRS, FAU, FCER1A, NR5A2, GAPDH, GARS, GATA3, GATM, GGT7, GHSR, GLO1, GPI, GPX1, GSS, HARS, HK2, HLCS, HPGD, HPN, IGF1, INS, INSIG1, LDHC, LIPA, LIPC, LTA4H, OAZ1, OAZ2, ODC1, P2RX7, P4HA1, PAM, PCK1, PDK4, PEPD, PFAS, PFKFB4, PGAM1, PGD, PGK2, PPP2R5D, PRKAA1, PRKAB2, PRKAG1, PRKAR2B, PRKCE, MAPK3, PROX1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PSPH, PTGIS, PTGS1, PTGS2, PYCR1, QARS, RBP1, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, RXRA, ACSM3, SHMT2, SLC2A3, SLC6A6, SLC6A8, SLC7A4, SLC10A1, SLCO1A2, SLC22A5, SMS, SNCA, SREBF1, STAT3, ELOVL4, SYK, TNFRSF1A, TYMS, TYR, UGT2B7, UGT8, NR1H2, UROS, AIMP2, SLC25A16, PDHX, SLC7A5, OGT, AKR1C3, ABCC3, VNN2, VNN1, SGPL1, SLC5A6, P4HA2, RPL14, RGN, RPL23, GRHPR, GSTO1, EIF2AK3, PSMF1, NR1D1, EIF4A3, PTDSS1, NR1H4, GNE, UST, SLC25A15, DHRS9, PSME3, PSMD14 |
1473 | GO:0009259 | 0.00 | 1.99 | 76.09 | 116 | 260 | ribonucleotide metabolic process | ABCA1, ACACB, ADCY1, ADCY7, ADCYAP1R1, ADSS, AK1, AK2, ALDOC, AMPD1, AMPD2, APRT, AQP1, ARNT, ATP1A2, ATP2B2, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V0A1, AVPR2, BAD, BPGM, TSPO, CACNB4, CALM3, COX8A, COX15, CRH, CTNS, DHODH, DLD, DLG2, DLG3, DRD3, DRD5, LPAR1, EDNRA, EDNRB, ENO2, PTK2B, FSHR, FZD2, GALR1, GAPDH, GCG, GHRHR, GNAI3, GNAS, GPI, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GUK1, GUCY2D, HK2, HMGCR, HPRT1, HTR2C, IGF1, IMPDH1, IMPDH2, INS, LDHC, NTRK2, OGDH, P2RX7, P2RY11, PALM, PDE4B, PDE8A, PFAS, PFKFB4, PGAM1, PGK2, PPP2R5D, PRKAA1, PRKAG1, PRPS2, PTH, RAF1, RCVRN, SDHC, SNCA, STAT3, SULT1E1, SULT1A3, SULT1C2, SULT2B1, TAZ, UPP1, UQCRC1, UQCRC2, UQCRH, VEGFA, VIP, VIPR2, WFS1, OGT, PDE5A, PAPSS1, COX5A, AKAP6, GABBR2, ENTPD4, AKAP12, GUCA1C, SLC25A13 |
1474 | GO:0008637 | 0.01 | 1.99 | 17.56 | 27 | 60 | apoptotic mitochondrial changes | SLC25A4, ATP2A1, BAD, BAX, BCL2A1, BCL2L1, BIK, BNIP3L, CAMK2A, CASP8, CLU, EYA2, IFI6, GPX1, HGF, HK2, IGF1, JUN, OPA1, PPP2CB, SOD2, YWHAH, YWHAZ, DYNLL1, HRK, TNFSF10, BCL2L11 |
1475 | GO:0045935 | 0.00 | 1.99 | 259.00 | 383 | 885 | positive regulation of nucleobase-containing compound metabolic process | ABCA1, ACVR1B, ACVRL1, ADAM8, ADCY7, ADCYAP1R1, AGTR2, AHR, ALK, ANXA3, APBB1, APP, ARF4, PHOX2A, ARNT, ARNTL, ASCL1, ATF3, ATF4, RERE, ATR, ATRX, AVPR2, BACH1, BAX, BCL3, BCL9, BMP3, BMP4, BMPR1A, BMPR2, BRCA2, BRDT, ZFP36L2, KLF5, BTK, CALM3, CAMK2A, CAT, RUNX2, CCNB1, CCNC, CCNE1, CCNT2, CD3D, CD28, CD86, TNFSF8, CD40, CDH1, CDK2, CDK8, CDX2, CEBPE, CEBPG, CHEK1, CHUK, CLU, COL1A1, CREB1, CRH, CRX, CSF2, CTH, DBP, DCN, DDX3X, DDX5, DKC1, DLX5, DNM2, DRD3, DRD5, ARID3A, E2F5, EBF1, EDA, S1PR1, EDNRA, EGR2, ELF1, ELF3, ELK1, ELK3, EN1, EP300, EPHA5, ERCC3, ERCC6, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV4, ETV5, ETV6, EVX1, EZH1, F2R, PTK2B, FGF4, FGF7, FSHB, FSHR, NR5A2, FZD2, GALR1, GATA3, GATA4, GATA6, GCG, KAT2A, GDNF, GHRHR, GNAS, GUCA1A, GUCA2A, GUCA2B, HAS3, HCLS1, HEXB, HGF, NRG1, HHEX, HMGN1, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HOXC11, HOXD8, HOXD9, HOXD10, HPN, HSF4, ICAM1, ID2, IFI16, IFNA2, IFNG, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL3, IL10, ILK, ING2, INS, INSIG1, IRAK1, ITGA6, IRAK2, IRF1, IRF5, ISL1, JUN, JUNB, JUND, JUP, KIT, LMO1, LTF, SMAD1, SMAD3, SMAD7, SMAD9, MEN1, MEOX2, KITLG, MGMT, CIITA, AFF1, FOXO4, PPP1R12A, NRF1, YBX1, NTRK2, DDR2, NVL, OTX1, OTX2, P2RX7, P2RY11, SERPINE1, PAX2, PAX3, PAX9, PCK1, PCNA, PGR, PHB, PHF2, PRKAA1, PRKCB, PRKCI, PRKD1, PRKCQ, MAPK1, MAPK3, PROX1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD9, PTCH1, PTEN, PTH, RAC1, RAD21, RAD51, RAF1, RAN, RARA, RARB, RB1, RCVRN, UPF1, REST, RET, RFX3, RFX4, RFXAP, RLF, RNF6, RPS3, RPS6KA1, RPS6KA3, RPS27A, RXRA, RXRG, S100A8, S100A9, S100A12, SALL1, ATXN7, SETMAR, TRA2B, SHC1, SIX3, SLC9A1, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCD3, SNAI1, SNRNP70, SOX4, SOX5, SOX9, SOX10, SOX11, SP1, SP3, SP100, SREBF1, SRF, SRY, TRIM21, SSRP1, STAT3, STAT4, STAT5B, STAT6, SUPV3L1, T, TAF7, TAL1, TBL1X, TBP, HNF1A, NR2F2, NR2E1, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C2, TRAF1, TRAF2, TRPS1, TNFSF4, UBB, UBE2V1, UBE3A, UNG, NR1H2, USF1, VDR, VEGFA, VIP, VIPR2, WFS1, WNT1, WNT11, YY1, YWHAH, ZIC1, CNBP, ZSCAN21, TRIM25, ZNF148, ZBTB17, ZP3, ZXDA, LRP8, FZD5, MAFK, ARHGEF5, FOSL1, FGF23, NRIP1, ARID1A, PICALM, EOMES, FZD4, FZD7, FZD8, UTF1, OGT, IKBKG, STK16, KLF7, TP63, TNKS, TRADD, RIPK1, TNFSF13, RIPK2, BUD31, PHOX2B, FUBP3, RPS6KA4, TNFSF18, RNF8, BAZ1B, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, AURKB, VAPB, CCPG1, RPS6KA5, ITGB1BP1, KLF4, HMGN3, TRIP4, HAND1, EIF2AK3, FHL5, ONECUT2, GTPBP1, NR1D1, CLOCK, BRE, CREB5, AKAP12, RNF14, GUCA1C, ZNF516, ARHGEF11, ZEB2, RNF10, NR1I3, NR1H4, NR1D2, NR2E3, PARP3, RAD50, YAF2, TRIM28, ALYREF, RNF41 |
1476 | GO:0006898 | 0.00 | 1.99 | 29.96 | 46 | 103 | receptor-mediated endocytosis | AP2B1, ALB, AMPH, ASGR1, CANX, CD5, CD5L, CD6, CD14, SCARB1, CDK5, AP2M1, AP1S1, AP2S1, COL1A1, DMBT1, CTTN, EPS15, FTL, HBA1, HBA2, HP, HPX, IGF2R, ITGA4, LRPAP1, OLR1, OPHN1, RAC1, SFTPD, ITSN1, SLC9A3, SORL1, SPARC, SYT1, SYT5, HSP90B1, LRP8, CLTCL1, PDLIM7, CD163, SNX17, DNAJC6, SNAP91, PRG4, RABEPK |
1477 | GO:0002260 | 0.02 | 1.98 | 11.71 | 18 | 40 | lymphocyte homeostasis | ABL1, ADA, BAX, TNFRSF17, CD74, TSC22D3, IL2RA, LMO1, P2RX7, RAG1, SOS2, SPTA1, STAT5B, IKBKG, TNFSF14, CCNB2, CHST3, BCL2L11 |
1478 | GO:0035264 | 0.01 | 1.98 | 14.31 | 22 | 49 | multicellular organism growth | ADD1, ATRX, BRCA2, DHCR7, EN1, ERCC6, G6PC, KAT2A, GPD2, HHEX, IHH, LLGL2, RARA, RARB, RBBP6, STIL, SLC12A2, SP2, TARBP2, KDM6A, XPA, XRCC2 |
1479 | GO:0035335 | 0.00 | 1.98 | 20.19 | 31 | 69 | peptidyl-tyrosine dephosphorylation | ACP1, CDC25A, CDC25C, DUSP1, DUSP5, DUSP7, DUSP9, EYA4, EYA2, PTEN, PTPN2, PTPN3, PTPN4, PTPN6, PTPN7, PTPN9, PTPN12, PTPN14, PTPRA, PTPRE, PTPRH, PTPRJ, PTPRN2, PTPRR, PTPRS, PTPRZ1, PTP4A1, DUSP11, CDC14B, DNAJC6, PTPRU |
1480 | GO:0050769 | 0.00 | 1.98 | 54.43 | 83 | 186 | positive regulation of neurogenesis | ABL2, BIN1, APBB1, ARF1, ASCL1, BMP4, BMPR2, TSPO, CNR1, CRX, CX3CR1, BRINP1, DCT, DNMT3B, DPYSL3, LPAR1, EFNA5, EPHA3, EPHA4, EPOR, ETV5, PTK2B, FYN, GFAP, GOLGA4, RAPGEF1, HGF, NRG1, FOXA2, ID2, IFNG, ILK, ITGB1, KIT, LIMK1, CAPRIN1, MAP1B, NRCAM, NTRK2, NTRK3, OPA1, P2RY2, PALM, PCP4, SERPINF1, PRKCI, PRKD1, PROX1, PTN, PTPRZ1, RAP1A, RARA, RARB, RET, RHEB, SALL1, CX3CL1, SGK1, SMARCD3, SOX10, SOX11, SRF, SYT1, SYT4, TP73, VEGFA, XRCC2, XRCC5, RNF112, LRP8, FZD3, RND2, SF3A2, SEMA7A, NUMB, NRP1, PHOX2B, CBFA2T2, SLIT2, RAPGEF2, RIMS2, CUL7, OLIG2 |
1481 | GO:0007423 | 0.00 | 1.98 | 28.01 | 43 | 97 | sensory organ development | ACTL6A, ACVR2B, ACVRL1, ASCL1, ATP2B1, BFSP1, BMPR2, CDK2, CDK4, CLCN2, CRX, CRYAB, CRYBA1, CRYBA4, CTNS, GPD2, GPM6A, HSF4, IMPDH1, IMPDH2, JUN, LIM2, SMAD3, NTF4, SERPINF1, RARA, RCN1, PRPH2, RET, RPL24, RRM1, RXRA, SMARCA4, SMARCD3, SOX3, SRF, NR2E1, TULP3, VIM, FZD4, KLF4, IFT140, ZEB2 |
1482 | GO:0034446 | 0.01 | 1.98 | 14.34 | 22 | 49 | substrate adhesion-dependent cell spreading | ABL1, ACTN4, AXL, DNM2, EFNA1, EPHB3, FBLN1, FGA, HAS2, ILK, ITGA4, ITGAV, PTK2, RAB1A, RAC1, RAC3, TYRO3, FZD4, FZD7, ARHGEF7, ITGB1BP1, ARPC2 |
1483 | GO:0042307 | 0.01 | 1.98 | 14.34 | 22 | 49 | positive regulation of protein import into nucleus | BMP4, BMPR1A, CDH1, EDA, HCLS1, IGF1, IL12B, IL18, JUP, KPNA1, IPO5, SMAD3, PRKCQ, PTGS2, SLC9A1, TRIP6, ZIC1, TNFSF14, IL18R1, AKAP6, TRIM28, NUTF2 |
1484 | GO:1903901 | 0.01 | 1.98 | 14.34 | 22 | 49 | negative regulation of viral life cycle | ADAR, BST2, IFI16, IFIT1, IFNA2, ISG20, JUN, LTF, OAS1, OAS3, PROX1, REST, SLPI, SP100, SRPK2, TRIM21, TRIM25, FCN3, OASL, VAPB, VAPA, TRIM28 |
1485 | GO:0002699 | 0.03 | 1.98 | 11.07 | 17 | 38 | positive regulation of immune effector process | ANXA1, CD86, CD36, CD37, CD74, FFAR3, IL13RA2, PDPK1, PHB, RAC2, RARA, RPS19, STXBP2, SEMA7A, RIPK2, CD84, PUM1 |
1486 | GO:0050728 | 0.01 | 1.97 | 16.97 | 26 | 58 | negative regulation of inflammatory response | ADA, BCR, CX3CR1, ETS1, GATA3, GHSR, GPX1, IL2RA, IL10, IL12B, INS, ISL1, SMAD3, SERPINF1, PROC, PSMB4, PTGIS, PTPN2, RPS19, TNFRSF1A, TNFRSF1B, TYRO3, PGLYRP1, SOCS3, KLF4, SLIT2 |
1487 | GO:0072524 | 0.00 | 1.97 | 19.61 | 30 | 67 | pyridine-containing compound metabolic process | ALDOC, ARNT, BPGM, DLD, ENO2, GAPDH, GPI, HK2, IDH1, IGF1, INS, MDH2, OGDH, P2RX7, PFKFB4, PGAM1, PGD, PGK2, PPP2R5D, PRKAA1, PRKAG1, PTGIS, PTGS2, RPE, STAT3, PDHX, OGT, KCNAB2, KYNU, TP53I3 |
1488 | GO:0042552 | 0.03 | 1.97 | 11.09 | 17 | 38 | myelination | CD9, LPAR1, EGR2, GPC1, HEXB, ILK, MAL, SCN2A, SCN8A, SLC8A3, TSC1, UGT8, ZNF24, ATRN, CNTNAP1, EIF2B2, OLIG2 |
1489 | GO:0060341 | 0.00 | 1.97 | 203.98 | 303 | 697 | regulation of cellular localization | ABAT, ABCA2, ABL1, ABL2, ACTL6A, ADAM8, ADCYAP1R1, ADRBK1, AGTR2, ALOX15B, ANG, ANGPT1, SLC25A4, ANXA1, ANXA4, ANXA5, APBB1, ARF1, ARL2, ARNTL, ATP1A2, ATP6AP1, BAD, BARD1, BAX, BCL2L1, BCL3, BCR, BDKRB1, BLK, BMP4, BMPR1A, BNIP3L, BST2, CACNA1A, CALM3, CAMK2A, CASP5, CASP8, CASQ1, CASQ2, CAV3, CCNB1, CD4, CD14, CD36, CD40, CD58, CDH1, CDK5, CDKN1A, CHRM1, CHRM3, CHRNB2, CHRNB4, AP2M1, CLTC, CNR1, CREB1, CRH, CRHBP, CRP, CRYAB, CSF1R, CSNK2A2, CTSK, CYBA, DIAPH1, DKC1, DNM1, DRD3, EDA, EDNRA, EFNA5, EPHA2, EMD, ENSA, EPHA5, F2, F2R, PTK2B, FBLN1, FCER1A, FGA, FGR, FYN, GALR1, GAS1, GATA3, GCG, KAT2A, GDF9, GDI1, GDNF, B4GALT1, GHRHR, GHSR, GLRA1, GLUD1, GNAQ, GNAS, GPLD1, GPM6B, GPR26, FFAR1, FFAR3, HCLS1, NRG1, HMGCR, FOXA2, HNMT, HRC, HTR2C, IFNA2, IFNG, IGF1, IL1A, IL10, IL12B, IL13, IL13RA2, TNFRSF9, IL18, INHA, INS, INSIG1, ISL1, ITGB1, ITPR1, ITPR3, JUP, KCNA5, KCNC2, KCNJ11, KCNN4, KCNS3, KISS1, KPNA1, IPO5, LLGL2, SMAD3, MAP1B, PPP1R12A, TONSL, NTRK2, NTSR1, OAZ1, OAZ2, OXCT1, OXTR, P2RX3, P2RX4, P2RX5, P2RX7, PAEP, PRDX1, PAM, PCM1, PCP4, PDPK1, PFN2, PLN, SEPT5, PPID, PPM1B, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRKCI, PRKD1, PRKCQ, MAPK1, MAPK3, PSMB7, PSMD8, PSMD9, PTAFR, PTEN, PTGS1, PTGS2, PTN, PTPN6, PTPN14, RAB3A, RAB3B, RAB5A, RAB27A, RAC2, RALA, RANGAP1, RAP1A, RB1, RBM4, REST, RFX3, RNASE2, RPL28, RYR2, XCL1, CX3CL1, SDC1, SDC4, SFRP5, SLC2A2, SLC8A1, SLC9A1, SNAP25, SNCA, SORL1, SOX4, SOX11, SP100, SPINK1, SREBF1, STXBP2, STXBP3, SYK, SYN1, SYT1, SYT4, SYT5, TACR2, TNNC1, TRAF2, TRH, TRIP6, TRPC1, TRPC3, TRPM2, TSG101, TNFSF4, UBE2L3, NR1H2, VEGFA, VIL1, YWHAH, YWHAZ, ZIC1, ZBTB17, SLC30A1, ZP3, FZD5, FGF23, AAAS, AKAP1, BAP1, FZD7, NR0B2, DYRK2, OGT, KCNAB2, RGS20, RUVBL1, NUMB, DYNLL1, VAMP8, TNFSF14, IL18R1, INPP4B, IQGAP1, CD84, SYNJ1, ARHGEF7, CDKL2, SYT7, IL1RL1, RAB11B, ITGB1BP1, HMGN3, RAB9A, SLC9A3R1, NRXN1, GSTO1, EIF2AK3, AKAP6, ATG5, CABP1, LITAF, GOSR1, TMEM59, BAG4, NR1D1, CLOCK, SNCAIP, RIMS2, ATG13, RIMS3, SPCS2, GAB2, C2CD5, FAM20B, NR1H4, PDCD6IP, BCL2L11, SAE1, TRIM28, NUTF2, STX6, RAMP3 |
1490 | GO:0070665 | 0.00 | 1.97 | 22.24 | 34 | 76 | positive regulation of leukocyte proliferation | ADA, ANXA1, CD3E, CD4, CD6, CD28, CD86, CD40, CD59, CD74, CDKN1A, CHRNB2, CD55, DHPS, EFNB1, IFNG, IGF1, IGF2, IL2RA, IL3, IL12B, IL13, IL18, ITGAL, KITLG, PRKCQ, XCL1, SPTA1, STAT5B, SYK, TNFSF4, ZP3, TNFSF9, RIPK2 |
1491 | GO:0007162 | 0.00 | 1.97 | 26.82 | 41 | 92 | negative regulation of cell adhesion | ABAT, ABL1, ABL2, ADAM10, ANGPT1, ANXA1, ARHGDIB, ARHGDIG, ASS1, BMP4, CBLB, CD74, CDH1, CTLA4, DTX1, HRG, IFNA2, IHH, IL1RN, IL2RA, IL10, IDO1, IRF1, KNG1, PRKAR1A, PRKG1, PTK2, PTPN2, PTPN6, CCL21, CCL25, XCL1, SFTPD, SIPA1, TNR, TNFSF4, SCGB1A1, PDE5A, TNFSF18, SOCS6, KLF4 |
1492 | GO:0035725 | 0.02 | 1.97 | 13.71 | 21 | 47 | sodium ion transmembrane transport | ATP1A1, ATP1A3, ATP12A, ATP4A, SCN1A, SCN2A, SCN7A, SCN8A, SCNN1A, SCNN1B, SCNN1G, SLC8A1, SLC8A3, SLC9A2, SLC9A3, SLC13A1, SLC20A1, SLC20A2, TRPM2, SLC4A7, HCN4 |
1493 | GO:0030278 | 0.01 | 1.97 | 16.33 | 25 | 56 | regulation of ossification | ATP6AP1, RUNX2, CDK6, DDX5, DLX5, EGR2, GNAS, HGF, ID1, ID2, IGF1, RBPJ, ILK, JUND, SMAD1, MEN1, P2RY2, PRKD1, PTCH1, PTK2, SOX11, TP63, CHRD, PDLIM7, RASSF2 |
1494 | GO:0007399 | 0.00 | 1.97 | 149.13 | 225 | 540 | nervous system development | ADAM10, ADCY1, AP2B1, ALK, ANGPT1, ANXA1, APBB2, ARAF, ASTN1, BCHE, PRDM1, DAGLA, CACNB1, CACNB2, CACNB4, CAMK2A, CAMK2G, CASP8, RUNX2, CD72, CHRM1, CHRM3, TBCB, AP2M1, AP2S1, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CSF2, CSF2RB, CSNK2A1, CSNK2A2, CSPG4, CTF1, CTNND2, DAPK3, DHFR, DLG2, DLG3, DLX5, DNM1, DNMT3A, EPYC, DUSP5, DUSP7, DUSP9, EDNRA, EFNA3, EFNA4, EFNB1, EFNB2, EPHA2, ELAVL3, EP300, EPHA8, ERCC3, ETV4, FGF3, FGF4, FGF6, FGF7, FGF11, GABRB2, GFRA1, GJB1, GLRB, GNAT1, GNAT2, GNGT1, GPM6A, GPM6B, GRB2, GRIN2A, GSS, PRMT1, IHH, IL2RA, IL2RB, IL2RG, IL3, INHA, ITGA1, ITGA2, ITGA5, ITGA9, ITGAV, JUN, KIF5A, LLGL2, MARK3, RAB8A, KITLG, ATXN3, NTN3, OMP, OPHN1, P2RX5, PENK, PEX7, PPP2R5D, PPP5C, PRKCQ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTPRA, PTPRR, PURA, RAB3A, RAC2, RAF1, RALA, RASA2, RB1, RFNG, RPGR, RPL24, RPS6KA1, RPS6KA2, RPS27A, RRAS, SCN2B, SDC4, SDHA, ITSN1, SHC1, SIAH2, SIM2, SMARCA2, SMARCA4, SMARCC1, SMARCE1, SMPD1, SOS2, SPG7, SPTA1, SPTB, ST14, STRN, T, TRIO, TRPC1, TRPC3, TRPC5, TULP1, TYROBP, CLRN1, KDM6A, VCL, WNT11, ZNF217, FZD5, MAFK, FGF23, SLC7A5, DPF1, PICALM, FZD7, FZD8, FZD9, CUL3, GAS7, KLF7, TP63, PEA15, RGS9, IQGAP1, NRP2, ARHGEF7, BSN, RPS6KA4, VAPA, RPS6KA5, COPS2, KL, SLC9A3R1, NRXN2, PICK1, CHST3, PSMF1, NRG2, FEZ2, IFT140, SPOCK2, ARHGEF11, RBX1, NR2E3, RANBP9, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, FRY, AKAP9, RASA4, ATP6AP2, FARP1, PSME3, PSMD14, IRX5 |
1495 | GO:0060041 | 0.01 | 1.96 | 18.99 | 29 | 65 | retina development in camera-type eye | ACTL6A, ATP2B1, BAX, BMP4, CLCN2, CRX, GNAT1, GNAT2, GPM6A, IMPDH1, IMPDH2, NTRK2, SERPINF1, PROX1, PTN, PRPH2, RET, RPGR, RPL24, RRM1, SIX3, SMARCA4, SMARCD3, SOX9, NR2E1, TULP1, IFT140, NR2E3, IRX5 |
1496 | GO:0050871 | 0.03 | 1.96 | 11.12 | 17 | 38 | positive regulation of B cell activation | ADA, BAD, PRDM1, BTK, CD28, CD40, CD74, CDKN1A, CHRNB2, IFNG, IL13, STAT5B, STAT6, SYK, TNFSF4, UNG, TNFSF13 |
1497 | GO:0031346 | 0.03 | 1.96 | 10.45 | 16 | 36 | positive regulation of cell projection organization | AQP1, BBS4, DNM2, EFEMP1, KAT2A, ITGA2, KIT, P2RX7, RAC1, RAC2, CLRN1, VIL1, WNT1, ARHGEF7, ARPC2, WASF2 |
1498 | GO:0009152 | 0.00 | 1.96 | 34.13 | 52 | 117 | purine ribonucleotide biosynthetic process | ABCA1, ACACB, ADCY1, ADCY7, ADCYAP1R1, ADSS, AK1, AK2, AMPD1, AMPD2, APRT, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V0A1, AVPR2, CALM3, CRH, DRD3, DRD5, LPAR1, EDNRA, EDNRB, FSHR, GALR1, GCG, GHRHR, GNAI3, GNAS, GUK1, LDHC, NTRK2, P2RY11, PALM, PFAS, PRPS2, PTH, RAF1, STAT3, VIP, VIPR2, WFS1, PAPSS1, AKAP6, GABBR2, AKAP12, SLC25A13 |
1499 | GO:0072331 | 0.00 | 1.96 | 32.19 | 49 | 110 | signal transduction by p53 class mediator | ATR, ATRX, BAX, BCL3, BOK, BRCA2, CD44, CD74, CDK2, CDKN1A, DDX5, EP300, HIC1, IFI16, ING2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RPS27A, SNAI1, SOX4, SP100, TP73, UBB, DYRK2, TP63, CRADD, PSMF1, PSME3, PSMD14 |
1500 | GO:0003158 | 0.01 | 1.96 | 16.39 | 25 | 56 | endothelium development | ACVR2B, ACVRL1, BMP4, BMPR2, S1PR1, ETV2, GJA4, GPX1, RAPGEF1, NRG1, ICAM1, ID1, RBPJ, KDR, PROC, PROX1, PTN, PTPRS, RAP1A, STC1, NR2F2, TNFRSF1A, VEZF1, NRP1, RAPGEF2 |
1501 | GO:0009057 | 0.00 | 1.96 | 20.90 | 32 | 73 | macromolecule catabolic process | ADAM8, BARD1, CAPN1, CBLB, CDK5, TPP1, CLN5, CTSE, ACE, ENPEP, FYN, GPLD1, GRIN2A, NRG1, IFNG, IL10, SMAD3, OAZ1, OAZ2, ODC1, P2RX7, PGA5, PHB, PTPN3, SORL1, SOX9, TNFRSF1B, TRAF2, UVRAG, VIP, TNFSF12, SEC22B |
1502 | GO:0009888 | 0.00 | 1.96 | 56.24 | 86 | 202 | tissue development | ADA, AMBN, AMELY, ASCL2, ATF3, BCL9, BGLAP, CACNB4, CASQ1, CCNB1, CDK5, CENPF, CCR1, COL19A1, CXADR, DCN, DDX5, TSC22D3, ECM1, EFNA1, EFNB1, EGR2, EMD, EPHA3, ERG, PTK2B, GAA, GPC1, GPM6B, HAS2, HLF, HMGCR, HOXD9, HOXD10, HPN, ITGA6, ITGAM, KCNK2, KRT6B, LTF, DDR2, OMD, OGDH, P2RX7, PLN, PRKAA1, PRKCQ, PTEN, PTH, PTPN12, RB1, REST, RPS6KB1, RYR1, S100A4, SEMA3F, SGCB, SGCD, SLC9A1, TAZ, KLF10, CLEC3B, TP73, TUFT1, COL14A1, ZBTB17, SEMA3B, KCNAB1, FGF23, SORBS2, SEMA7A, ADAM15, SAP30, NRP2, PHOX2B, USP2, CTDP1, ITGB1BP1, COPS2, GTF3C5, KL, AKAP6, ATG5, MINPP1, CUL7, NR1D2 |
1503 | GO:0051246 | 0.02 | 1.95 | 11.62 | 18 | 43 | regulation of protein metabolic process | ANPEP, ARNTL, BARD1, CBLB, CTSG, ENPEP, GFAP, GHRHR, ATXN3, OAZ1, OAZ2, ODC1, RAB1A, VIP, CUL4A, TNFSF12, LIPG, SEC22B |
1504 | GO:0032412 | 0.04 | 1.95 | 10.49 | 16 | 36 | regulation of ion transmembrane transporter activity | FXYD2, DRD3, KCNJ1, KCNQ1, KCNS1, KCNS2, FXYD3, PRKCE, PTPN3, SCN2B, SCN4B, YWHAH, KCNAB1, RIPK1, SLC9A3R1, OXSR1 |
1505 | GO:0051051 | 0.02 | 1.95 | 12.44 | 19 | 43 | negative regulation of transport | ATF4, PTK2B, GPM6B, ICAM1, ITGAV, KCNA5, PRKAA1, PRKCB, PRKD1, PTEN, PTGS2, RAC1, STC1, NR1H2, VIP, PICALM, PEA15, UNC119, RUBCN |
1506 | GO:1903320 | 0.00 | 1.95 | 56.19 | 85 | 192 | regulation of protein modification by small protein conjugation or removal | ABL1, ANGPT1, BIRC3, XIAP, ARNT, AVPR2, BMI1, BUB1, BUB1B, TSPO, CAV3, CCNB1, CDC20, CDC27, CDK2, CDK5, CENPF, CLU, DUSP1, PTK2B, FGFR3, FYN, DNAJB2, LIMK1, MAD2L1, SMAD7, PRKCE, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, RPS3, RPS27A, SIAH2, SKP1, SKP2, SUMO3, SOX4, TRIM21, TTK, UBB, UBE2D1, UBE2L3, UBE3A, USP4, WFS1, WNT1, ZNF207, AIMP2, CUL1, OGT, CDC14B, CDC23, RIPK2, CDC16, ZW10, BUB3, TRIP12, ATG5, PSMF1, BAG5, RNF40, FEM1B, PSME3, PSMD14 |
1507 | GO:0098662 | 0.00 | 1.95 | 68.72 | 104 | 238 | inorganic cation transmembrane transport | ABL1, ANXA5, ATP2A1, ATP2B1, ATP2B2, ATP2B3, BAX, BDKRB1, BMP4, CACNA1A, CACNA1B, CACNB1, CACNB2, CACNB4, CACNG1, CALM3, CASQ1, CASQ2, CNGA1, CNGA2, CYBA, DIAPH1, DPP6, EDNRA, F2, F2R, PTK2B, GPM6A, XCR1, GRIN2A, HPN, HRC, HTR2C, IL13, ITGAV, ITPR1, ITPR3, KCNA1, KCNA3, KCNA4, KCNA5, KCNC2, KCND2, KCND3, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN4, KCNQ1, KCNS1, KCNS2, KCNS3, NTSR1, P2RX1, P2RX7, PDE4B, PDPK1, PIK3C2A, PLN, PRKD1, PTPN6, REST, RYR1, RYR2, S100A1, CCL21, XCL1, SNCA, TRPC1, TRPC3, TRPC4, TRPC5, SUMO1, TRPV1, SLC30A1, SLC30A2, ZP3, KCNAB1, KCNAB2, RGN, KCNAB3, KCNK6, GSTO1, AKAP7, AKAP6, ATG5, ATP2C2, OXSR1, SLC12A6, ABCC9, KCNK7, AKAP9, KCNMB2 |
1508 | GO:0010811 | 0.04 | 1.95 | 10.50 | 16 | 36 | positive regulation of cell-substrate adhesion | ARL2, DNM2, FBLN1, FBLN2, FGA, HAS2, ITGA5, ITGB1, PRKCE, PTN, RAC3, RSU1, VTN, ARHGEF7, SPOCK2, ARPC2 |
1509 | GO:0030218 | 0.04 | 1.95 | 10.51 | 16 | 36 | erythrocyte differentiation | ADAR, ADD1, ALAS2, BMP4, CDK6, ETV2, GATA3, HCLS1, INHA, KIT, PTPN2, RHAG, RPS19, SRF, STAT5B, VEGFA |
1510 | GO:0050671 | 0.00 | 1.94 | 21.07 | 32 | 72 | positive regulation of lymphocyte proliferation | ADA, ANXA1, CD3E, CD4, CD6, CD28, CD86, CD40, CD59, CD74, CDKN1A, CHRNB2, CD55, DHPS, EFNB1, IFNG, IGF1, IGF2, IL2RA, IL12B, IL13, IL18, ITGAL, PRKCQ, XCL1, SPTA1, STAT5B, SYK, TNFSF4, ZP3, TNFSF9, RIPK2 |
1511 | GO:0008203 | 0.01 | 1.94 | 18.44 | 28 | 63 | cholesterol metabolic process | ABCA1, APOF, APLP2, APP, CAT, SCARB1, CYP11B1, DHCR7, CYB5R3, FDFT1, FDPS, HMGCR, HMGCS2, INSIG1, LCAT, LIPC, LIPE, PRKAA1, RXRA, SORL1, SQLE, SREBF1, TNFSF4, CNBP, NR0B2, GGPS1, SNX17, NR1H4 |
1512 | GO:0009611 | 0.01 | 1.94 | 15.65 | 24 | 56 | response to wounding | BIRC3, XIAP, DST, C7, CASP5, CCR1, CR1, CTGF, CD55, EDNRB, GFAP, GRIN2A, IL1R1, CFP, PHB, PSMA6, RPS6KB1, SRSF5, SCGB1A1, WNT1, SEMA7A, IL1RL2, NRP1, NR1D2 |
1513 | GO:0099565 | 0.04 | 1.94 | 10.52 | 16 | 36 | chemical synaptic transmission, postsynaptic | TSPO, CDK5, CHRNB2, CHRNB4, SLC29A1, PTK2B, GABRA4, GRID2, GRIN2A, P2RX4, P2RY11, PTEN, SNCA, DGKI, NRXN1, EIF4A3 |
1514 | GO:0002764 | 0.01 | 1.94 | 19.66 | 30 | 69 | immune response-regulating signaling pathway | ADAM8, BIRC3, XIAP, CD14, CD36, CTSH, CTSK, CTSS, CYBA, DMBT1, ELK1, IRAK1, IRAK2, IRF1, ITGAM, LTF, PPP2R5D, RPS6KA1, RPS6KA2, RPS6KA3, SEC14L1, HSP90B1, TYRO3, RIPK1, PGLYRP1, NR1D1, PUM1, TRIL, NR1H4, TANK |
1515 | GO:0042100 | 0.02 | 1.94 | 13.17 | 20 | 45 | B cell proliferation | ABL1, ADA, AHR, BAX, PRDM1, CD40, CD74, CDKN1A, CHRNB2, CR2, CTLA4, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IL10, IL13, RAG2 |
1516 | GO:0048477 | 0.04 | 1.94 | 10.54 | 16 | 36 | oogenesis | ANG, BRCA2, CCNB1, DIAPH2, PTK2B, GDF9, HEXB, IGF1, IHH, PPP2R1A, RPS6KA2, TAF4B, ZP3, PDE5A, KIAA0196, REC8 |
1517 | GO:0009968 | 0.00 | 1.94 | 86.46 | 130 | 299 | negative regulation of signal transduction | ADAR, AP2B1, AES, AGTR2, NR0B1, BAX, PRDM1, CBL, CBLB, AP2M1, AP2S1, COL2A1, CRHBP, CRY2, CSF2, CTH, CTNNA1, CTNND1, CX3CR1, ECM1, ELF1, CTTN, EPS15, FBN1, FGA, FGF9, FYN, IFI6, GATA3, GDNF, GPC1, GRB2, HGF, NRG1, HHEX, HIC1, ONECUT1, HRG, ICAM1, IGFBP3, IGFBP6, IHH, IL1A, IL1RN, ITGA6, ISL1, ITGA1, ITGAV, LRPAP1, LTF, SMAD3, SMAD6, SMAD7, CNOT2, YBX1, SERPINE1, PDPK1, PPP1CA, PRKCB, PRKCQ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTPRE, RAF1, RFNG, RGS1, RGS10, RPS6KB1, RPS27A, ATXN7, CX3CL1, SIAH2, SIX3, SLAMF1, SMARCA4, SOX9, SOX10, ADAM17, TYRO3, UBB, NR1H2, WNT1, WNT11, SCG2, FZD6, MADD, RGS20, NUMB, PEA15, RGS9, DLK1, NRP1, ARHGEF7, LATS1, ZFYVE9, ONECUT2, PSMF1, NR1D1, CLOCK, ADAMTSL2, ZNF536, EIF4A3, RB1CC1, RBX1, HMGXB4, IL18BP, G3BP1, PSME3, PSMD14, STAM2 |
1518 | GO:0097659 | 0.00 | 1.94 | 23.52 | 36 | 85 | nucleic acid-templated transcription | ANG, COX6A1, COX6B1, COX7B, COX7C, COX8A, CSTF3, CTGF, GPI, GPX2, GTF3C1, GTF3C2, DRG1, PRDX1, PPP5C, PRKAB2, PRKAG1, PTMA, RGS12, RHEB, SRSF1, SRSF5, SRSF7, SNRPE, SNRPF, PRDX2, TSC1, YWHAZ, SRSF9, DDX21, GTF3C5, GTF3C4, GTF3C3, COX5A, DHX38, RBM8A |
1519 | GO:0009187 | 0.01 | 1.94 | 15.15 | 23 | 52 | cyclic nucleotide metabolic process | ADCY1, AMPD2, AQP1, ATP2B2, CACNB4, CNP, DRD3, LPAR1, EDNRB, PTK2B, GALR1, GNAI3, GUCY2C, GUCY2F, GUCY2D, HTR2C, PALM, PDE4B, PDE8A, VEGFA, PDE5A, AKAP6, GABBR2 |
1520 | GO:0002009 | 0.00 | 1.94 | 48.37 | 73 | 166 | morphogenesis of an epithelium | ABL1, ABL2, ACVRL1, AGTR2, BAX, CAV3, CD44, CHUK, CSF1R, CTSH, DLG3, EDNRA, EFNB2, CELSR2, EPHA2, EPHA4, ETV4, ETV5, GPC4, FGF3, FGF7, FGFR3, FOXD1, GATA4, B4GALT1, GPC3, GRB2, HGF, FOXA2, IGF1, IGF1R, RBPJ, IHH, IL10, ILK, ITGA5, KDR, KRT16, SMAD3, PGR, SERPINB5, PPP1CA, PRKX, PSPN, PROX1, RAC1, RXRA, RYK, RYR2, SCNN1B, SLC12A2, SNAI1, SOX10, SRF, ADAM17, VCL, VDR, VEGFA, WNT1, WNT11, FZD5, FZD7, NUMB, HESX1, NRP1, SOCS3, KLF4, SLIT2, SLC9A3R1, SEMA3E, FEM1B, TRIM28, SPRY1 |
1521 | GO:0040013 | 0.00 | 1.93 | 42.44 | 64 | 145 | negative regulation of locomotion | ACVRL1, ADA, AGTR2, ALOX15B, ANGPT2, APOH, ARHGAP4, ARHGDIB, BCR, BST2, KRIT1, CD63, CTNNA1, CX3CR1, DCN, DPEP1, DPYSL3, FBLN1, GATA3, HAS1, NRG1, HRG, IFNA2, IGFBP3, ILK, ITGAV, KRT16, SMAD7, SERPINE1, SERPINF1, PFN2, PTEN, PTN, PTPN2, PTPRJ, PTPRR, RAP2A, RAP2B, RRAS, CCL21, CCL25, SEMA3F, SP100, SRF, STAT3, STC1, NR2F2, VCL, WAS, WNT11, TRIM25, SEMA3B, FCN3, CHRD, ADAM15, NRP1, RGN, ITGB1BP1, KLF4, SLIT2, SLC9A3R1, SEMA3E, PTPRU, RNF41 |
1522 | GO:0000122 | 0.00 | 1.93 | 112.67 | 168 | 385 | negative regulation of transcription from RNA polymerase II promoter | ACVR2B, AEBP1, AES, NR0B1, AHR, ASCL1, ASCL2, ATF3, RERE, ATRX, BACH1, PRDM1, BMI1, BMP4, KLF5, CD36, CDX2, CHD4, CRY2, DDX5, DNMT1, DNMT3A, DNMT3B, DRD3, ATN1, TSC22D3, E2F6, E4F1, EDNRB, EFNA1, EN1, EP300, ERF, ETS2, ETV3, ETV6, FGF9, FGFR3, GATA3, GATA6, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HBE1, HCLS1, HDGF, HHEX, HIC1, FOXA2, HOXD8, HOXD9, HSBP1, HSF4, ID1, ID2, IFI16, IFNG, RBPJ, ISL1, JARID2, JUN, JUNB, JUND, LMO1, SMAD3, SMAD7, MEN1, CIITA, CNOT2, YBX1, ORC2, OVOL1, PAX3, PEG3, PHB, PPID, PROX1, PTCH1, PTH, PURB, RARA, RARB, RB1, RBBP8, REST, RNF2, RPS27A, RXRA, S100A1, SALL1, SATB1, SFPQ, SIM2, SMARCA2, SMARCA4, SNAI1, SNCA, SOX3, SOX11, SP3, SP100, SREBF1, SRF, SRY, STAT3, STAT6, T, TAF7, TAL1, TBL1X, GCFC2, NR2F1, NR2F2, KLF10, NR2E1, TP73, NR2C1, TRPS1, UBB, UBE2D1, SCGB1A1, NR1H2, VDR, VEGFA, WFS1, YY1, ZNF136, ZNF148, ZNF157, ZNF174, ZNF177, ZNF189, ZNF217, LRP8, NRIP1, USP9X, ARID1A, EOMES, FZD8, GFI1B, SOX14, UXT, NR0B2, CUL3, KLF11, TP63, EED, SAP30, PER3, RNF8, USP2, AURKB, KLF4, COPS2, RECQL5, HAND1, ZNF254, NR1D1, PHF14, ST18, VPRBP, ZNF536, ZEB2, NR1H4, NR2E3, TRIM28, OLIG2 |
1523 | GO:0009628 | 0.00 | 1.93 | 28.14 | 43 | 102 | response to abiotic stimulus | ATP2B1, CAMK2A, CAMK2G, CASQ1, CD9, CDH8, TSC22D3, EIF2B1, HMGCS2, HNMT, HSBP1, HSPA6, HSPB2, IL1A, IMPDH1, ATXN3, MKI67, NUP98, PCP4, PDPK1, MAPK1, DNAJC3, RANBP2, RPA2, RPA3, SORD, TACR3, DNAJC7, NUP214, AAAS, SLC14A2, SNN, EIF2B3, EIF2B2, EIF2AK3, BAG5, BAG4, BAG2, NUP155, ZNF516, NUP93, HDAC6, PDCD6 |
1524 | GO:0051146 | 0.00 | 1.93 | 32.49 | 49 | 111 | striated muscle cell differentiation | AGTR2, BCL9, BMP4, CACNB4, CASQ1, CASQ2, CAV3, CCNB1, CHUK, CXADR, EFNB2, FLT3LG, GATA4, GATA6, KAT2A, GPX1, NRG1, IGF1, IGF2, RBPJ, ITGB1, YBX1, PRKAR1A, PROX1, RARA, RARB, RB1, RXRA, RYR1, SORT1, SDC1, SGCB, SLC8A1, SLC9A1, SRF, TSC1, COL14A1, VEGFA, WNT1, IFT88, ARID1A, SORBS2, TNFSF14, DYRK1B, CTDP1, AKAP6, ATG5, GDF15, WDR1 |
1525 | GO:0060284 | 0.00 | 1.93 | 57.10 | 86 | 198 | regulation of cell development | ABL1, ACTN4, APP, ARHGAP4, ASCL2, BMPR1A, CACNA1A, CDC20, CDK5, CHN1, CHRNB2, CREB1, CTNNA1, DBN1, DCC, DDX6, DRD3, DTX1, EDNRB, EFNA1, EIF4E, ELAVL1, EMX1, CTTN, EPHB3, F2, FBLN1, EFEMP1, FGFR3, GATA3, GDI1, GRID2, HPN, ID1, IGF1, INS, ISL1, LTF, SMAD7, CNOT2, NTF4, PCM1, PPP2R1A, PTEN, PTK2, RAP1GAP, RAP2A, REST, RNF6, RPS19, SEMA3F, SIX3, SLC6A4, SNAP25, SORL1, SOX3, SOX5, SOX9, SPOCK1, STAT3, TAL1, CNTN2, DYNLT1, NR2E1, TNFRSF1A, TNR, TTC3, TYROBP, VIM, TRPV1, YWHAH, SEMA3B, EOMES, SOX14, ARHGEF1, ARHGEF2, ITGB1BP1, KLF4, BAG5, AATK, SEMA3E, ZNF536, KIAA0319, RNF10, WDR1, PQBP1 |
1526 | GO:0045995 | 0.02 | 1.92 | 15.22 | 23 | 52 | regulation of embryonic development | BMP4, BMPR1A, CDX2, E4F1, FZD2, GATA3, GDNF, FOXA2, IGF1, IL1RN, LAMA3, LAMA4, OTX2, PAX3, PRKACB, SNAI1, NR2C2, TULP3, WNT1, FZD3, FZD7, KLF4, RBM19 |
1527 | GO:0009966 | 0.00 | 1.92 | 25.50 | 39 | 94 | regulation of signal transduction | BIRC5, APLP2, APP, CNGA1, CRH, CD55, DBH, DTX1, EP300, FNTA, GAS1, GNAT1, GNGT1, GUCA1A, GUCY2F, GUCY2D, IFNGR1, IRF1, KCNJ1, LLGL2, OTX2, PRCP, RCVRN, RNF6, SP100, STAT2, SYP, DYNLT1, TRAF1, TYK2, SUMO1, ZIC1, TAX1BP1, BAZ1B, RNF14, GUCA1C, IFT140, FEM1B, RAMP3 |
1528 | GO:0032844 | 0.03 | 1.92 | 11.21 | 17 | 39 | regulation of homeostatic process | ADA, CD36, CD74, CDK6, TSC22D3, ERCC4, UBE2K, HNRNPC, IL2RA, LMO1, KITLG, PRKAA1, STAT5B, ADAM17, NR1H2, XRCC5, NR1D2 |
1529 | GO:0000086 | 0.00 | 1.92 | 34.53 | 52 | 118 | G2/M transition of mitotic cell cycle | BIRC5, APP, BACH1, CCNB1, CDC25A, CDC25C, CDK2, CDK4, CDKN1A, CENPF, CHEK1, CSNK1D, DYNC1H1, DNM2, ENSA, EP300, RAB8A, FOXO4, PPP1R12A, PPP1R12B, NUMA1, PCM1, ABCB1, PPP2R1A, PPP2R2A, PRKAR2B, PRKCQ, RAD51C, RAD51B, RBBP4, RPS27A, SKP1, SKP2, SMARCD3, TPD52L1, TUBA4A, TUBG1, UBB, TUBA1A, CUL1, PPM1D, SSNA1, DYNLL1, PHOX2B, LATS1, CCNB2, CEP135, CEP57, CKAP5, SFI1, ACTR1A, AKAP9 |
1530 | GO:0007189 | 0.03 | 1.92 | 12.58 | 19 | 43 | adenylate cyclase-activating G-protein coupled receptor signaling pathway | ADCY1, ADCY7, ADRA1B, DRD3, DRD5, FSHR, GALR1, GHRHR, GNAQ, GNAS, GPR3, GPR26, PTGER2, PTH, VIP, S1PR4, GPR52, SLC9A3R1, RAPGEF2 |
1531 | GO:0006310 | 0.00 | 1.92 | 40.57 | 61 | 139 | DNA recombination | ABL1, ACTL6A, ATR, ATRX, BARD1, BRCA2, CDK2, CHEK1, ERCC4, FEN1, RBPJ, IL10, KPNA1, KPNA2, TONSL, PCNA, PPP4C, PRIM2, RAD21, RAG1, RAG2, RBBP8, RFC1, RFC3, RFC4, RFC5, RPA2, RPA3, RPS27A, SFPQ, SUPV3L1, TOP2A, TOP2B, TSN, UBB, SUMO1, WRN, XRCC5, YY1, HIST1H4I, CDC45, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, RUVBL1, HERC2, RNF8, EXO1, RECQL5, IL27RA, BRE, VPRBP, REC8, RAD50, ALYREF, PSMD14 |
1532 | GO:0051960 | 0.00 | 1.92 | 111.00 | 165 | 380 | regulation of nervous system development | ABL1, ABL2, BIN1, APBB1, APP, ARF1, ARHGAP4, ARNTL, ASCL1, ASCL2, ADGRB2, BMP4, BMPR1A, BMPR2, TSPO, CACNA1A, CDC20, CDK5, CHN1, CHRNB2, CNR1, CREB1, CRX, CTNNA1, CX3CR1, BRINP1, DBN1, DCC, DCT, DDX6, DNM2, DNMT3B, DPYSL3, DRD3, DTX1, LPAR1, EDNRB, EFNA1, EFNA5, EIF4E, EMX1, CTTN, EPHA3, EPHA4, EPHB1, EPHB2, EPHB3, EPOR, ETV5, F2, PTK2B, EFEMP1, FGFR3, FYN, FZD2, GATA3, GDI1, GFAP, GHSR, GOLGA4, RAPGEF1, GRID2, FOXA2, ID1, ID2, IGF1, ILK, ISL1, ITGB1, KIT, LIMK1, CAPRIN1, MAP1B, NRCAM, NTF4, NTRK2, NTRK3, OPA1, OXTR, P2RY2, PALM, PAX2, PCM1, PCP4, SERPINF1, PRKACB, PRKCI, PRKD1, PROX1, PTK2, PTN, PTPRZ1, RAC1, RAC3, RAP1A, RAP1GAP, RAP2A, REST, RET, RFX4, RHEB, RNF6, SALL1, CX3CL1, SEMA3F, SGK1, SIX3, SLC6A4, SMARCD3, SNAP25, SORL1, SOX3, SOX5, SOX9, SOX10, SOX11, SPOCK1, SRF, STAT3, SYT1, SYT4, CNTN2, DYNLT1, NR2E1, TNR, TP73, TPBG, TTC3, TULP3, VEGFA, VIM, XRCC2, XRCC5, YWHAH, RNF112, LRP8, SEMA3B, FZD3, RND2, SF3A2, EOMES, SOX14, SEMA7A, CHRD, NUMB, NRP1, PHOX2B, ARHGEF1, CBFA2T2, ARHGEF2, KLF4, SLIT2, NRXN3, NRXN1, BAG5, AATK, RAPGEF2, RIMS2, SEMA3E, ZNF536, CUL7, KIAA0319, WDR1, PQBP1, OLIG2 |
1533 | GO:0051338 | 0.03 | 1.92 | 11.85 | 18 | 42 | regulation of transferase activity | APLP2, APP, CCNE1, CDC25A, CDC25C, CDK4, CKS1B, PRKAB2, RAC2, RAP2B, RBL2, TSC1, TSG101, UVRAG, PIK3R3, IKBKAP, DIRAS3, SLC9A3R1 |
1534 | GO:0032846 | 0.00 | 1.92 | 21.22 | 32 | 73 | positive regulation of homeostatic process | ABAT, ACOX1, ADAM8, AGTR2, ANXA1, ATP6AP1, ATR, ATRX, BAD, CASQ2, CNR1, CRH, DKC1, DRD3, EDNRB, FSHB, GCG, GPLD1, KNG1, OXCT1, PRKCQ, MAPK1, MAPK3, PTGS2, RYR2, SLC22A5, SMARCA4, SYK, SLC30A2, TNKS, AURKB, RAD50 |
1535 | GO:0046822 | 0.00 | 1.91 | 33.95 | 51 | 116 | regulation of nucleocytoplasmic transport | AGTR2, ANGPT1, BARD1, BCL3, BMP4, BMPR1A, CD36, CDH1, CDK5, CDKN1A, EDA, EMD, GNAQ, HCLS1, IGF1, IL10, IL12B, IL18, JUP, KPNA1, IPO5, SMAD3, PPP1R12A, TONSL, PRDX1, PPM1B, PRKCQ, PTGS2, PTPN14, RANGAP1, RBM4, SFRP5, SLC9A1, SOX4, SP100, TRIP6, ZIC1, AAAS, AKAP1, FZD7, DYRK2, RGS20, TNFSF14, IL18R1, INPP4B, SLC9A3R1, AKAP6, CABP1, LITAF, TRIM28, NUTF2 |
1536 | GO:0044281 | 0.00 | 1.91 | 70.88 | 107 | 259 | small molecule metabolic process | ABCB7, ALAD, ALAS2, SLC25A4, ARF1, ARL2, ARSA, STS, ARSD, ARSE, ARSF, BLVRA, BMP1, CA1, CA4, CA6, SLC25A20, CD36, CD44, CHRM3, CLPS, COX6A1, COX6B1, COX7B, COX7C, CPOX, CTGF, CTRB1, CYC1, DBH, DIO1, DNM2, FABP2, FABP7, FMO3, GALC, GIF, GM2A, GNB2, GNG3, GNG10, FFAR1, HAS1, HAS3, HBA1, HBA2, HMBS, HSD11B1, ITPR1, ITPR3, KCNC2, KCNS3, NUBP1, NUP98, ABCB1, PIK3C2A, PIK3C2B, PI4KA, PIP4K2A, PPT1, PRKAR1A, PRKAR1B, PRKAR2A, PRKD1, PSAP, ABCD4, RAN, RAP1A, RBP2, RHAG, RLBP1, SAT1, SLC2A2, SLC2A4, SLC2A5, SLC4A1, SLC9A1, SLC22A1, SLC22A3, SLC22A2, SMARCD3, SNAP25, SP1, SYT5, TBL1X, TPMT, UCP1, UQCRFS1, LRP8, NUP214, AAAS, PIK3R3, AGPS, PEX11A, CES2, IQGAP1, MGAM, SLC25A14, VAPB, VAPA, LIPG, NUP155, HS2ST1, NUP93, HS3ST1, ABCC5, COL4A3BP |
1537 | GO:0007094 | 0.05 | 1.91 | 9.95 | 15 | 34 | mitotic spindle assembly checkpoint | BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, DUSP1, MAD2L1, TTK, UBE2D1, ZNF207, CDC23, CDC16, ZW10, BUB3 |
1538 | GO:0043297 | 0.05 | 1.91 | 9.95 | 15 | 34 | apical junction assembly | ACTN4, ARL2, CLDN3, CTNNA1, ITGB1, PRKCI, SNAI1, SRF, STRN, TBCD, VCL, WNT11, FZD5, CLDN12, CLDN1 |
1539 | GO:0043647 | 0.05 | 1.91 | 9.95 | 15 | 34 | inositol phosphate metabolic process | ADCYAP1R1, CALM3, PTK2B, HRH1, INPP1, INPPL1, NTSR1, OCRL, PTAFR, PTEN, SNCA, INPP4B, SYNJ1, MINPP1, PPIP5K1 |
1540 | GO:0048704 | 0.05 | 1.91 | 9.95 | 15 | 34 | embryonic skeletal system morphogenesis | ALX3, BMP4, RUNX2, COL2A1, COL11A1, GNAS, HOXC11, HOXD4, HOXD9, HOXD10, SMAD3, SOX11, TULP3, EIF4A3, IRX5 |
1541 | GO:0070664 | 0.05 | 1.91 | 9.95 | 15 | 34 | negative regulation of leukocyte proliferation | PRDM1, BMP4, CBLB, CTLA4, IHH, IL2RA, IL10, IDO1, PRKAR1A, PTPN6, XCL1, SFTPD, SOX11, SCGB1A1, PDE5A |
1542 | GO:0046887 | 0.01 | 1.91 | 17.27 | 26 | 59 | positive regulation of hormone secretion | ABAT, BAD, BLK, CREB1, CRH, FGA, GALR1, GCG, GHRHR, GLUD1, GPLD1, FFAR1, INHA, INS, ISL1, KISS1, OXCT1, PRKCE, PSMD9, SOX4, SOX11, TRH, TRPM2, NR0B2, VAMP8, ARHGEF7 |
1543 | GO:0048592 | 0.01 | 1.91 | 16.63 | 25 | 57 | eye morphogenesis | ALDH1A3, AQP1, AQP5, BAX, BMP4, CRYGB, EPHA2, FBN1, EFEMP1, FGFR3, HMGN1, KDR, PAX2, PROX1, RARB, SIX3, SOX11, SP1, SP3, YY1, FZD5, ARID1A, BCAR3, MFN2, IRX5 |
1544 | GO:0016458 | 0.03 | 1.91 | 11.96 | 18 | 41 | gene silencing | CDK2, DNMT1, DNMT3A, DNMT3B, HIST1H2AD, HMGA1, KCNQ1, CHMP1A, PHF2, TBP, ARID1A, CDC45, HIST1H2AK, HIST2H2AC, HAT1, HIST1H2AG, TAF1B, TAF1A |
1545 | GO:0007269 | 0.01 | 1.90 | 16.63 | 25 | 57 | neurotransmitter secretion | ABAT, CACNA1B, CDK5, CHAT, GAD1, P2RX7, PPT1, PTPRN2, SLC1A6, SLC6A13, SLC22A2, SNAP25, SYT1, SYT4, SYN3, STX11, SNAP23, LIN7A, SYNJ1, DGKI, SNAP29, NRXN3, NRXN1, NRXN2, RIMS2 |
1546 | GO:0045930 | 0.04 | 1.90 | 11.28 | 17 | 39 | negative regulation of mitotic cell cycle | ABL1, ATRX, BMP4, CHEK1, BRINP1, FGFR3, GAS1, SMAD3, OVOL1, PTEN, PTPN3, SMARCA4, FZD3, TNKS, SLC9A3R1, CTDSP2, CTDSPL |
1547 | GO:0050801 | 0.00 | 1.90 | 77.81 | 116 | 269 | ion homeostasis | ABCA1, ABCB7, ABL2, ADRA1B, ALAS2, ANXA6, XIAP, APLP2, APP, ARF1, ATP1A1, ATP1A3, ATP12A, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP4A, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, AVPR1B, CACNA1A, CACNB4, CD36, CD40, CD52, CLCN3, CLN5, CCR1, CCR3, CCR8, CPS1, CRH, CYP27B1, CD55, DRD5, S1PR1, LPAR1, EPOR, FTL, GALR1, GNA15, GNAT2, GNG3, GRINA, GRM1, GTF2I, HEXB, HPX, INS, IREB2, ITGB1, KCNA1, KCNA5, KCNH2, KCNJ2, KCNJ10, KCNK3, KISS1, LTF, NUBP1, OXTR, P2RY2, P2RY4, PDK4, PPT1, PRKAA1, PRKCB, PTH, PYGM, RHAG, S100A8, S100A9, SCN7A, SCNN1A, SCNN1B, SCNN1G, SCO1, SGK1, SLC4A1, SLC8A3, SLC9A1, SLC9A2, SLC9A3, SLC34A1, STC1, TNNI3, TPT1, HSP90B1, TRPC4, TRPC5, TRPM2, UPK3A, VDR, WFS1, FGF23, PICALM, CYP4F2, DGAT1, S1PR4, INPP4B, ATP6V0E1, RGN, ATP6V0D1, XPR1, VAPB, KL, SLC9A3R1, LIPG, ATP6V1G1, ATP2C2, ABCB6, SGK2 |
1548 | GO:0015672 | 0.00 | 1.90 | 89.45 | 133 | 308 | monovalent inorganic cation transport | ACTN4, ARF1, ATF4, ATP1A1, ATP1A2, ATP1A3, ATP12A, FXYD2, ATP4A, ATP4B, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, CASQ2, CAV3, CD63, CDK2, CNGA1, CNGA2, COX6A1, COX6B1, COX7A1, COX7B, COX7C, COX8A, COX15, CYB5A, DNM2, DPP6, PTK2B, HPN, IL13, KCNA1, KCNA3, KCNA4, KCNA5, KCNC2, KCND2, KCND3, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN4, KCNQ1, KCNS1, KCNS2, KCNS3, P2RX4, P2RX7, FXYD3, PRKCE, PRSS8, PTPN3, REST, SCN1A, SCN2A, SCN2B, SCN4B, SCN5A, SCN7A, SCN8A, SCNN1A, SCNN1B, SCNN1G, SGK1, SLC5A2, SLC6A8, SLC8A1, SLC8A3, SLC9A1, SLC9A2, SLC9A3, SLC10A1, SLC12A1, SLC13A1, SLC15A1, SLC34A1, SLC20A1, SLC20A2, SNTA1, TRPM2, TSC1, SUMO1, UCP1, UQCRC1, UQCRFS1, UQCRH, VIP, YWHAH, KCNAB1, KCNAB2, SLC5A6, ATP6V0E1, SLC25A14, SLC13A2, ATP6V0D1, KCNAB3, SLC9A3R1, COX5A, KCNK6, AKAP7, AKAP6, SLC4A7, ATP6V1G1, OXSR1, SLC12A6, HCN4, ABCC9, KCNK7, SGK2, AKAP9, KCNMB2 |
1549 | GO:0001894 | 0.01 | 1.90 | 18.65 | 28 | 64 | tissue homeostasis | ABCA4, ACTB, ALB, BARD1, BBS4, CLCN3, COL2A1, COL9A1, CTGF, CTSH, CXADR, ERCC6, FGF7, GNAS, HSPB1, ITGB1, KCNJ1, KDR, LTF, P2RX4, PRDX1, SFTPD, SLC22A5, SRF, TULP1, CLRN1, VEGFA, CROCC |
1550 | GO:0006979 | 0.02 | 1.90 | 13.29 | 20 | 46 | response to oxidative stress | ALAD, APP, CHUK, ERCC3, ETFDH, FGF8, GSS, IDH1, NUDT1, PTGS1, PTGS2, SEPP1, TAT, WRN, XPA, ATRN, PDLIM1, OXSR1, SGK2, RCAN2 |
1551 | GO:0008652 | 0.01 | 1.90 | 16.68 | 25 | 57 | cellular amino acid biosynthetic process | ABAT, AHCY, ASL, ASNS, ASPA, ASS1, BCAT2, BHMT, CDO1, CPS1, CTH, DHFR, DHPS, GAD1, GATM, GLUD1, GOT2, GPT, OAT, PAH, PSPH, PYCR1, SHMT1, SHMT2, ALDH4A1 |
1552 | GO:0043085 | 0.04 | 1.90 | 10.56 | 16 | 38 | positive regulation of catalytic activity | TRIM23, ARF1, CLPS, HSPB2, IGFBP3, PPP1R12B, PSAP, RFC1, SFTPB, NSMAF, OGT, PRKRA, GTF3C4, GMFG, UBA2, SAE1 |
1553 | GO:0008219 | 0.00 | 1.89 | 65.79 | 99 | 242 | cell death | ACP2, ACVR1B, ADD1, AHR, ALOX15B, ANXA6, APP, ATP2A1, BMPR2, BMX, BRCA2, BUB1B, CD5, CD5L, CD28, TNFSF8, CD70, CDK11B, CDH1, CLC, CSE1L, CSNK2A2, BRINP1, DDX5, DFFB, DNASE1, DNASE1L3, ATN1, EPHA2, EIF4G2, EIF5A, EMP2, EP300, ERCC6, EYA2, FNTA, GAPDH, GAS2, GNGT1, GZMH, HIC1, UBE2K, HK2, IAPP, IFI16, IFNA2, IL2RA, IRF1, ITPR1, KPNA1, MEOX2, OLR1, P2RX4, PAEP, PAX3, PEG3, PPP2CB, PRKCB, PRKCE, MAPK1, MAPK3, PTH, PTPN6, PTPRH, RAD21, RB1, DPF2, RYR2, SATB1, SCN2A, SFRP5, SHB, SIX3, TOP1, VDAC1, VIM, XPA, FZD5, DPF1, DYRK2, CUL4A, CUL3, CUL2, CUL1, RGS20, TNFSF9, SGPL1, RABEP1, VAPA, BCL7C, BCL7B, SLC4A7, LITAF, BRE, AATK, SNCAIP, MFN2, PDCD6IP, RNF41 |
1554 | GO:0048638 | 0.01 | 1.89 | 18.01 | 27 | 62 | regulation of developmental growth | ABL1, ARHGAP4, BMP4, CAV3, CDK5, CXADR, DCC, DNM2, CTTN, FGFR3, KCNK2, NRCAM, PTEN, PTK2, RNF6, SEMA3F, SLC6A4, TNR, TP73, COL14A1, SEMA3B, LATS1, CTDP1, SLIT2, AATK, SEMA3E, BCL2L11 |
1555 | GO:0030595 | 0.04 | 1.89 | 11.34 | 17 | 39 | leukocyte chemotaxis | ADAM8, CX3CR1, CXADR, EDNRB, HRH1, IFNG, IL10, ITGA1, ITGA9, PDE4B, S100A8, S100A9, SFTPD, SYK, VAV1, SCG2, ARHGEF5 |
1556 | GO:0072593 | 0.01 | 1.89 | 20.05 | 30 | 69 | reactive oxygen species metabolic process | ARF4, CAT, CRYAB, CTGF, CYP1A2, DRD5, GPX1, HBA1, HBA2, HK2, HP, P2RX7, PRDX1, PAX2, PDK4, PRCP, RAC1, RAC2, SFTPD, SOD2, SOD3, STAT3, SYK, PRDX2, VAV1, VDAC1, STK17A, ATG5, HDAC6, TRAP1 |
1557 | GO:0043405 | 0.00 | 1.88 | 32.81 | 49 | 114 | regulation of MAP kinase activity | ADAM8, ALK, CAV3, CD40, CD74, CSPG4, DUSP1, LPAR1, EFNA1, EPHA4, PTK2B, FCER1A, FLT3, FPR1, GNG3, HGF, HMGCR, IGF1R, ILK, IRAK1, IRAK2, ITGA1, NTRK3, P2RX7, PPP2R1A, PRKAA1, PTPN6, PTPRJ, RPS3, S100A12, SMPD1, SORL1, SYK, TP73, TPD52L1, TRAF2, TSG101, VEGFA, FZD5, ARHGEF5, FZD4, FZD8, IKBKG, MADD, PDE5A, RIPK1, RIPK2, ZEB2, SPRY1 |
1558 | GO:0043009 | 0.00 | 1.88 | 28.80 | 43 | 100 | chordate embryonic development | ALX3, APAF1, BBS4, BMP4, RUNX2, COL1A1, COL2A1, COL11A1, EPHA2, EN1, FGF8, FGF9, FZD2, GNAS, HOXC11, HOXD4, HOXD9, HOXD10, ISL1, OPA1, PAX2, PCSK5, PRKACB, PROX1, RALA, RARA, SALL1, SDC4, SOX4, SOX11, TSC1, TULP3, WNT1, WNT11, FZD3, ARID1A, FZD6, CHRD, DLK1, IFT140, EIF4A3, ATP6AP2, IRX5 |
1559 | GO:0006261 | 0.04 | 1.88 | 11.39 | 17 | 39 | DNA-dependent DNA replication | BMP4, BRCA2, CCNE1, CDC6, CDK2, HMGA1, TONSL, ORC1, ORC2, ORC4, PURA, RAD51, REV3L, SETMAR, WRN, CDK2AP1, ALYREF |
1560 | GO:0006163 | 0.00 | 1.88 | 51.17 | 76 | 176 | purine nucleotide metabolic process | ACACB, ADA, ADCY1, ADSS, AK1, AK2, ALDOC, AMPD1, AMPD2, APRT, AQP1, ATP1A2, ATP2B2, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V0A1, BAD, BPGM, CACNB4, CAT, COX8A, COX15, CTNS, DLD, DLG2, DLG3, ENO2, PTK2B, GAPDH, GPI, GPX1, GUCY2C, GUCY2F, GUK1, GUCY2D, HK2, HMGCR, HPRT1, HTR2C, IMPDH1, IMPDH2, LDHC, NUDT1, OAS1, OGDH, PDE4B, PDE8A, PFAS, PFKFB4, PGAM1, PGK2, PPP2R5D, PRKAG1, PRPS2, SDHC, SULT1E1, SULT1A3, SULT1C2, SULT2B1, TAZ, UQCRC1, UQCRC2, UQCRH, VEGFA, OGT, PDE5A, PAPSS1, COX5A, SLC25A13 |
1561 | GO:0001843 | 0.02 | 1.88 | 16.10 | 24 | 55 | neural tube closure | APAF1, BBS4, BMP4, FZD2, KAT2A, OPA1, PAX2, PAX3, PRKACB, PTCH1, RALA, RARA, SALL1, SDC4, STIL, ST14, T, TSC1, TULP3, KDM6A, FZD3, ARID1A, FZD6, ZEB2 |
1562 | GO:0055086 | 0.00 | 1.88 | 105.36 | 155 | 360 | nucleobase-containing small molecule metabolic process | ABCA1, ACACB, ACPP, ADA, ADCY1, ADCY7, ADCYAP1R1, ADSS, AHCY, AK1, AK2, ALDOC, AMPD1, AMPD2, APRT, AQP1, ARNT, ATP1A2, ATP2B2, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V0A1, AVPR2, BAD, BPGM, TSPO, CACNB4, CALM3, CAT, ENTPD2, CDA, CNP, COX8A, COX15, CPS1, CRH, CTNS, DHFR, DHODH, DLD, DLG2, DLG3, DNMT1, DNMT3A, DNMT3B, DRD3, DRD5, TYMP, LPAR1, EDNRA, EDNRB, ENO2, PTK2B, FSHR, FZD2, GALR1, GAPDH, GARS, GCG, GHRHR, GNAI3, GNAS, GPI, GPX1, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GUK1, GUCY2D, HK2, HMGCR, HPRT1, HTR2C, IDH1, IGF1, IMPDH1, IMPDH2, INS, LDHC, MDH2, NUDT1, NTHL1, NTRK2, OAS1, OGDH, P2RX7, P2RY11, PALM, PDE4B, PDE8A, PFAS, PFKFB4, PGAM1, PGD, PGK2, PPP2R5D, PRKAA1, PRKAG1, MAPK1, PRPS2, PRPSAP1, PTGDR, PTGIS, PTH, PTGS2, RAF1, RCVRN, RPE, RRM1, RRM2, SDHC, SHMT1, SNCA, STAT3, SULT1E1, SULT1A3, SULT1C2, SULT2B1, TAZ, TYMS, UNG, UPP1, UQCRC1, UQCRC2, UQCRH, VEGFA, VIP, VIPR2, WFS1, PDHX, OGT, KCNAB2, PDE5A, SUCLG1, MBD4, KYNU, PAPSS1, COX5A, AKAP6, TBPL1, TP53I3, GABBR2, ENTPD4, AKAP12, GUCA1C, SLC25A13 |
1563 | GO:0045596 | 0.00 | 1.88 | 97.16 | 143 | 332 | negative regulation of cell differentiation | ABCA1, ACTN4, ACVRL1, NR0B1, ANXA1, APP, ARHGAP4, ARNTL, ASCL1, ASCL2, BMP4, BMPR1A, ZFP36L2, TSPO, CAV3, CD74, CDK5, CDK6, CRP, CTLA4, CTNNA1, DCC, DDX6, DPYSL3, DRD3, DTX1, LPAR1, EDNRB, EFNA1, EIF4E, EPHA4, F2, PTK2B, FBLN1, EFEMP1, FGFR3, FLT3, GATA3, GDI1, GFAP, NRG1, FOXA2, HPN, PRMT1, IAPP, ID1, ID2, IFNA2, IFNG, IGF1, RBPJ, IHH, IL13, IL18, INHA, INSIG1, IRF1, ISL1, ITGAV, ITGB1, LTF, SMAD3, SMAD7, MEN1, FOXO4, YBX1, NTRK3, REG3A, PAX2, PCM1, MAPK1, PTCH1, PTEN, PTK2, PTN, PTPN2, PTPRZ1, RAP1GAP, RARA, RARB, REST, RNF6, SORT1, SALL1, SEMA3F, SIX3, SLC6A4, SNAI1, SORL1, SOX3, SOX9, SOX11, SPOCK1, STAT3, STAT5B, CNTN2, DYNLT1, NR2E1, TNR, TP73, TTC3, TNFSF4, NR1H2, VIM, TRPV1, WNT1, YWHAH, SEMA3B, FGF23, HIST1H4I, FZD7, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, TP63, CHRD, INPP4B, NRP1, PHOX2B, PGLYRP1, TNFSF18, ARHGEF1, CBFA2T2, CTDP1, ARHGEF2, ITGB1BP1, GPR55, SLIT2, BAG5, CXCL14, AATK, RAPGEF2, SEMA3E, ZNF536, KIAA0319, RNF10, OLIG2 |
1564 | GO:0006612 | 0.00 | 1.88 | 33.66 | 50 | 115 | protein targeting to membrane | BSG, CACNB1, CDK5, FAU, GDI1, PALM, PRKCI, PTCH1, PEX19, PEX5, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, SRP9, SRP14, SSR3, OGT, RPL14, ITGB1BP1, RPL23, PEX16, SPCS2, C2CD5 |
1565 | GO:0043627 | 0.03 | 1.87 | 12.72 | 19 | 44 | response to estrogen | AQP1, STS, BGLAP, CRH, CTNNA1, CYP27B1, EP300, F7, GATA3, GATA4, GATA6, GHRHR, SMAD6, MFGE8, SERPINB9, MAPK1, PTPRN, TRIM25, RGS9 |
1566 | GO:0061387 | 0.01 | 1.87 | 18.14 | 27 | 62 | regulation of extent of cell growth | ABL1, ARHGAP4, BMPR2, CDK5, DCC, DNM2, EFNA5, CTTN, GOLGA4, NRG1, ILK, LIMK1, MAP1B, NRCAM, NTRK3, RNF6, SEMA3F, SRF, TNR, VEGFA, SEMA3B, RND2, SEMA7A, NRP1, SLIT2, AATK, SEMA3E |
1567 | GO:0048814 | 0.04 | 1.87 | 11.41 | 17 | 39 | regulation of dendrite morphogenesis | CDK5, CHRNB2, EFNA1, EPHA4, ID1, ILK, CAPRIN1, PTEN, PTPRZ1, RAP2A, SGK1, NR2E1, YWHAH, LRP8, RAPGEF2, CUL7, PQBP1 |
1568 | GO:0060675 | 0.04 | 1.87 | 11.41 | 17 | 39 | ureteric bud morphogenesis | AGTR2, BMP4, CD44, FGF8, FOXD1, GATA3, GDNF, GPC3, ILK, PAX2, PSPN, PTCH1, SALL1, SOX9, VEGFA, WNT1, WNT11 |
1569 | GO:0007204 | 0.02 | 1.87 | 14.76 | 22 | 51 | positive regulation of cytosolic calcium ion concentration | ABL2, ADRA1B, AVPR1B, CACNA1A, CAV3, CD36, CD52, CCR1, CCR3, CCR8, CD55, EDNRB, EPOR, GALR1, GNA15, GNAT2, GNG3, KNG1, OXTR, P2RY2, P2RY4, S1PR4 |
1570 | GO:0042742 | 0.01 | 1.87 | 17.50 | 26 | 60 | defense response to bacterium | ANXA3, BCL3, BPI, CD4, CEBPE, CYBA, COCH, HP, IFNG, RBPJ, IL10, IL12B, SERPINE1, CFP, PRG2, RAB1A, S100A7, S100A8, S100A9, S100A12, CXCL6, SELP, SFTPD, SYK, TNFRSF1A, ADAMTS4 |
1571 | GO:0006767 | 0.03 | 1.87 | 13.46 | 20 | 46 | water-soluble vitamin metabolic process | ACACB, ACPP, CTRB1, CYB5A, DHFR, CYB5R3, GIF, HLCS, PTGIS, PTGS2, ABCD4, SHMT1, SHMT2, SLC2A3, SLC25A16, VNN2, VNN1, SLC5A6, RGN, GSTO1 |
1572 | GO:0071495 | 0.00 | 1.87 | 31.31 | 47 | 115 | cellular response to endogenous stimulus | ACVR2B, ADRBK1, XIAP, BMP1, BMP3, BMP8B, BMPR2, RUNX2, CD9, CD28, CD86, CD36, CD44, CDKN1A, CHUK, COL2A1, CTGF, DLX5, EGR3, ETV2, FOXD1, GATA3, GPC3, GPC1, RBPJ, ILK, ITGB1, ITPR1, KCND3, OTX2, PPP2CB, PPP2R1A, PTEN, RAP1GAP, RPS6KB2, SYK, T, VAV1, SHOC2, CHRD, PHOX2B, BMP15, ITGB1BP1, CEP57, ZFYVE16, FGFBP1, SPRY1 |
1573 | GO:0044282 | 0.00 | 1.86 | 63.80 | 94 | 218 | small molecule catabolic process | ABAT, ACACB, ACADM, ACADS, ACAT1, ACOX1, ADH5, AHCY, ABCD1, ALDH1B1, ALDH3B2, ALDOC, ARG1, ASL, ASPA, ALDH7A1, AUH, BAD, BCAT2, BCKDHA, SCARB1, CDO1, CNR1, CPT1B, CPT2, CRAT, SLC25A10, CTH, CYP27B1, DAO, DBT, DLD, ECH1, EHHADH, ENO2, ESD, ETFA, ETFDH, FAAH, FUT6, FUT8, GAD1, GALE, GAPDH, GK2, GLDC, GLUD1, GOT2, GPD2, GPI, GPT, GSTZ1, HADHA, HK2, HNMT, HPD, HSD17B4, IDUA, IDO1, INPP1, IVD, LIPC, LIPE, NUDT1, NTSR1, OAT, OGDH, OXCT1, PAH, PEX7, PEX13, PFKFB4, PGAM1, PPP2R5D, PTEN, ABCD3, QDPR, RENBP, RPE, SHMT1, SMPD1, SORD, SUOX, TAT, FGF23, ACOX3, DDO, CYP4F2, AKR1C3, ALDH4A1, SYNJ1, KYNU, SNX17, XYLB |
1574 | GO:0015980 | 0.00 | 1.86 | 28.98 | 43 | 100 | energy derivation by oxidation of organic compounds | ACO2, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, BAX, CAT, COX6A1, COX6B1, COX7B, COX7C, COX8A, COX15, CYC1, CYP1A2, DLD, ETFA, ETFDH, IDH1, IDH3A, MDH2, OGDH, SDHA, SDHB, SDHC, SDHD, SNCA, TAZ, UCP1, UQCRC1, UQCRC2, UQCRFS1, UQCRH, SLC25A12, SUCLG1, SLC25A14, COX5A, TRAP1, SLC25A13 |
1575 | GO:0009165 | 0.00 | 1.86 | 31.72 | 47 | 109 | nucleotide biosynthetic process | ACACB, ADCY1, ADSS, AK1, AK2, AQP1, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V0A1, DHFR, DHODH, DRD3, LPAR1, EDNRB, PTK2B, GALR1, GARS, GNAI3, GUCY2C, GUCY2F, GUK1, GUCY2D, HTR2C, IMPDH1, IMPDH2, LDHC, OAS1, PALM, PFAS, PRPS2, PRPSAP1, RRM1, RRM2, SHMT1, TYMS, KYNU, PAPSS1, AKAP6, TBPL1, GABBR2, SLC25A13 |
1576 | GO:0006897 | 0.00 | 1.86 | 43.25 | 64 | 150 | endocytosis | ABCA1, ABL1, ABL2, ACTB, BIN1, ANXA1, ANXA3, ANXA11, APP, ARR3, BCL2L1, BLK, CD3G, CEBPE, CLCN3, CRP, FCGR2A, FCN2, FGR, FYN, INPPL1, ITPR1, ITPR3, LIMK1, P2RX7, PIK3C2A, PRKCE, PRKD1, PTEN, PTK2, RAB1A, RAB4A, RAB5B, RARA, SORT1, SLAMF1, SIGLEC1, SNX2, SYP, ICAM5, TYRO3, UBE3A, NR1H2, VAV1, WAS, EEA1, FCN3, PSTPIP1, RABEP1, CYTH2, TRIP10, ZFYVE9, RIN1, CLINT1, RUBCN, ZFYVE16, TOM1, ATP9A, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, WASF2 |
1577 | GO:0055088 | 0.01 | 1.86 | 17.56 | 26 | 60 | lipid homeostasis | ABCA1, ABCA2, ACADM, ACADS, ACOX1, CAV3, SCARB1, ETFA, NR5A2, G6PC, HPN, INS, IVD, LCAT, LIPC, PRKAA1, ACSM3, NR1H2, USF1, ACOX3, DGAT1, LIPG, NR1D1, NR1H4, NR1D2, COL4A3BP |
1578 | GO:0045944 | 0.00 | 1.85 | 147.40 | 214 | 505 | positive regulation of transcription from RNA polymerase II promoter | ACVR1B, ACVRL1, AHR, APBB1, APP, ARF4, PHOX2A, ARNT, ARNTL, ASCL1, ATF3, RERE, ATRX, BACH1, BCL3, BCL9, BMP3, BMP4, BMPR1A, BMPR2, KLF5, CCNC, CCNT2, CD3D, CD28, TNFSF8, CD40, CDK8, CEBPE, CEBPG, CHUK, CREB1, CRX, DBP, DCN, DDX3X, DDX5, DRD3, ARID3A, E2F5, EBF1, S1PR1, EGR2, ELF1, ELF3, ELK1, ELK3, EN1, ERCC3, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV4, ETV5, ETV6, EVX1, EZH1, FGF4, FSHB, NR5A2, GALR1, GATA3, GATA4, GATA6, GCG, KAT2A, GDNF, HCLS1, HEXB, HGF, NRG1, HHEX, HMGA1, NR4A1, ONECUT1, HOXC11, HOXD8, HOXD9, HOXD10, HSF4, ID2, IFI16, IFNG, IGF1, IGF2, IHH, IL1A, IL10, INSIG1, ITGA6, IRF1, IRF5, ISL1, JUN, JUNB, JUND, LMO1, SMAD3, SMAD7, MEN1, MEOX2, CIITA, FOXO4, PPP1R12A, NRF1, YBX1, OTX1, OTX2, SERPINE1, PAX2, PAX3, PAX9, PCK1, PGR, PRKD1, MAPK3, PROX1, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PTH, RAD21, RAF1, RARA, RARB, RB1, REST, RFX3, RFX4, RLF, RPS6KA1, RPS6KA3, RPS27A, SALL1, ATXN7, SIX3, SLC9A1, SMARCA2, SMARCA4, SMARCC1, SOX4, SOX5, SOX9, SOX10, SOX11, SP1, SP3, SREBF1, SRF, STAT3, STAT4, STAT5B, STAT6, T, TAF7, TAL1, TBL1X, HNF1A, NR2E1, TNFRSF1A, TOP2A, TP73, NR2C2, TRPS1, UBB, UBE3A, NR1H2, VDR, WNT1, YY1, ZIC1, CNBP, ZSCAN21, ZNF148, FZD5, MAFK, FOSL1, NRIP1, EOMES, FZD8, UTF1, OGT, IKBKG, STK16, TP63, TNKS, RIPK1, RIPK2, BUD31, PHOX2B, FUBP3, RPS6KA4, CBFA2T2, ARHGEF2, CCPG1, RPS6KA5, ITGB1BP1, KLF4, HMGN3, HAND1, EIF2AK3, FHL5, ONECUT2, CLOCK, ZEB2, RNF10, NR1I3, NR1H4, NR2E3, TRIM28 |
1579 | GO:0061061 | 0.00 | 1.85 | 33.82 | 50 | 117 | muscle structure development | ABL1, AGTR2, BIN1, CACNB4, CASQ2, CDH15, CHUK, CSRP2, CTH, CTNNA1, EDNRB, FGF6, FLOT2, FLT3LG, KAT2A, HSPB2, IGF2, IGFBP3, IL18, ILK, ITGB1, YBX1, NTN3, PRKAR1A, RARA, RARB, RBM4, REST, SORT1, SDC1, SLC8A1, SLC9A1, SMARCA2, SMARCD3, SOX9, SRF, T, NR2C2, TSC1, VEGFA, WNT1, IFT88, ARID1A, SORBS2, TNFSF14, DYRK1B, ATG5, GDF15, CXCL14, WDR1 |
1580 | GO:0002698 | 0.05 | 1.85 | 10.81 | 16 | 37 | negative regulation of immune effector process | ANGPT1, ANXA1, CD59, CD55, IFIT1, IL2RA, IL10, INS, PCBP2, PPM1B, RPS19, SEC14L1, TARBP2, TNFSF4, PGLYRP1, TNFSF18 |
1581 | GO:0048523 | 0.00 | 1.85 | 39.18 | 59 | 153 | negative regulation of cellular process | ADRBK1, AP2B1, ARF1, BICD1, BPI, CD3E, AP2S1, CTNND1, DNM1, DRD5, EPHA2, ELF1, EPS15, GLRA1, GNAI1, GPM6B, GRB2, GRIA1, IFIT1, ISG20, LRPAP1, OAS1, OAS3, OVGP1, PPM1B, PPP2CB, PRKCB, PTPRE, RASA2, RFNG, RFX4, RGS1, RGS10, RGS12, RGS13, SEC14L1, SLAMF1, SRPK2, TRIP6, TULP3, TRIM25, DYRK2, RGS20, OASL, PTCH2, RGS9, DLK1, ARHGEF7, DGKI, VAPB, VAPA, CABP1, LITAF, RBX1, HMGXB4, IL18BP, G3BP1, RASA4, STAM2 |
1582 | GO:0006818 | 0.00 | 1.85 | 29.85 | 44 | 102 | hydrogen transport | ACTN4, ATP1A1, ATP1A2, ATP1A3, ATP12A, ATP4A, ATP4B, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, COX6A1, COX6B1, COX7A1, COX7B, COX7C, COX8A, COX15, CYB5A, DRD3, IL13, SLC9A1, SLC9A2, SLC9A3, SLC15A1, UCP1, UQCRC1, UQCRFS1, UQCRH, ATP6V0E1, SLC25A14, ATP6V0D1, SLC9A3R1, COX5A, ATP6V1G1 |
1583 | GO:1903729 | 0.05 | 1.85 | 10.83 | 16 | 37 | regulation of plasma membrane organization | BCL2L1, AP2M1, CLTC, DNM2, EPHA2, IFNG, ITGB1, PDPK1, PRKCI, S100A9, VIL1, NUMB, VAMP8, NRXN1, TMEM59, RAMP3 |
1584 | GO:0048513 | 0.00 | 1.84 | 120.13 | 177 | 459 | animal organ development | ACTN1, ACVR1B, ADAM8, ADAR, ADD1, ALAS2, ALOX15B, AMELY, APRT, ARHGAP5, STS, ASNS, ATP6AP1, BCL3, BMI1, BMP3, BMP8B, BMX, ZFP36L2, BTK, TSPO, CACNB4, CASP9, CASP10, CD3D, CD3E, CD4, CD8A, CD28, CD86, TNFSF8, CD74, CDO1, CEBPE, CEBPG, CCR1, CPS1, CR2, CTLA4, DBP, DHODH, DNASE1L2, DTX1, ECM1, EDNRB, EFNB1, SLC29A1, EPHA3, ETV6, EVPL, PTK2B, GLO1, GPLD1, GPM6B, HCLS1, HK2, PRMT1, HSD17B3, IFI16, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IL2RA, IL12B, IRF1, IVL, JARID2, JUP, KRT2, KRT9, KRT16, LIPC, MGMT, DDR2, OMD, REG3A, PHF2, PIP4K2A, PPIB, PRL, PSAP, PTH, PTPN2, PTPN6, PURB, QDPR, RAG1, RAG2, RAP1GAP, RHAG, RPL22, RPS19, RRAS, S100A4, S100A7, SATB1, SEMA3F, SOS2, SOX5, SOX10, SPRR2A, SPRR2D, SPRR2E, SPRR2G, SPRR3, SPTA1, SPTB, ADAM17, KLF10, CLEC3B, TOP2A, TPD52, TSG101, TNFSF4, TYR, TYROBP, XRCC5, ZNF16, SEMA3B, FGF23, MADCAM1, HIST1H4I, PICALM, FZD8, FZD9, GFI1B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL4A, KCNAB2, PIR, AP3B1, PTCH2, TRADD, RIPK1, TNFSF9, RIPK2, SCEL, IL1RL2, IL18R1, INPP4B, NRP2, ARHGEF7, VNN1, AP3D1, PGLYRP1, TNFSF18, CLDN1, LATS1, CCNB2, DYRK1B, ITGB1BP1, GPR55, KL, NRG2, MINPP1, SOX13, TRAF4, ZNF516, SEMA3E, VPRBP, RASSF2, ZBTB24, GAB2, WASF2, RNF41, DHRS2, PRG4 |
1585 | GO:0060563 | 0.03 | 1.84 | 12.88 | 19 | 44 | neuroepithelial cell differentiation | ASCL1, ATP2B2, EDNRB, EMX1, FGF8, GNAQ, RBPJ, KIT, KITLG, RAB27A, RAC1, SOX4, SOX10, SOX11, CLRN1, WNT11, SLC9A3R1, SLC4A7, ZEB2 |
1586 | GO:0001523 | 0.02 | 1.84 | 14.93 | 22 | 51 | retinoid metabolic process | ABCA4, ADH5, ALDH1A3, OPN1SW, AKR1C4, CLPS, GPC4, GPC5, OPN1MW, GPC3, GPC1, RBP1, RBP2, OPN1LW, RLBP1, SDC1, SDC4, LRP8, AKR1C3, DGAT1, SDC3, DHRS9 |
1587 | GO:0051100 | 0.01 | 1.84 | 19.02 | 28 | 65 | negative regulation of binding | AES, BAX, GOLGA2, ID1, ID2, IFI16, IFIT1, IL10, ISL1, ITGA4, JUN, LRPAP1, PLN, PPP1CA, MAPK3, PEX19, RAP1GAP, SLPI, SORL1, SOX11, SP100, SUMO1, TNKS, ADAM15, AURKB, ITGB1BP1, HAND1, EIF4A3 |
1588 | GO:0010817 | 0.00 | 1.84 | 36.71 | 54 | 127 | regulation of hormone levels | ACVR2B, AGTR1, AGTR2, ALDH1A3, ANPEP, AQP1, ARNT, ATP1A1, BCAT2, CAMK2G, SCARB1, AKR1C4, COMT, CTSG, CYP3A4, CYP11B1, ACE, DIO1, ENPEP, FSHB, GATA3, HPN, HSD17B3, HSD17B4, IL1RN, PCSK5, PTPRN, PTPRN2, RAB1A, RAF1, RBP1, SLC22A1, SRD5A1, STAT5B, SULT1E1, STXBP3, SERPINA7, HNF1A, UGT2B7, VIP, FZD4, LTBP4, DDO, AKR1C3, DGAT1, SNAP23, SGPL1, PCSK7, RAB11B, EIF2AK3, RIMS2, ATP6AP2, DHRS9, DHRS2 |
1589 | GO:0032101 | 0.00 | 1.83 | 62.11 | 91 | 216 | regulation of response to external stimulus | ACTL6A, ADAM10, AP2B1, ARF1, ATP6V0A1, BMPR2, BNIP3L, CD4, CD36, CD37, CD74, AP2M1, AP1S1, AP2S1, CCR1, CMKLR1, COX8A, CSNK2A2, CTSK, CYBA, CYP27B1, DCN, S1PR1, LPAR1, EFNB2, CTTN, F2R, F3, F7, PTK2B, FGF4, FGF7, FYN, GABRA5, KAT2A, CXCL2, CXCL3, FOXA2, HSPB1, KCNQ1, KDR, NTHL1, NTRK3, PDK4, PEX13, PF4V1, PIP4K2A, PRKD1, RAC1, RAC2, RPL28, S100A7, SCN1A, CCL21, CXCL6, CXCL5, SELP, SNRPD1, SREBF1, STAT2, SYK, ADAM17, VDAC1, VEGFA, VEGFB, ZBTB17, ZNF189, FZD5, SCG2, IFT88, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, RUVBL1, TNFSF14, AP1M1, HIST1H3F, USP14, RAB33A, CHST3, ATG5, CXCL14, PPM1F, NUP93, PUM1, PHYHIP, FGFBP1, HDAC6, AP1M2 |
1590 | GO:0030154 | 0.00 | 1.83 | 270.97 | 385 | 999 | cell differentiation | ACTB, ACTN1, ADAM10, ADCY1, ADCYAP1R1, ADD1, AP2B1, ALAS2, ALK, ANG, ANGPT1, ANGPT2, ANPEP, APAF1, APBB2, ARAF, ARF4, PHOX2A, ASTN1, RERE, BBS4, BCL2L1, BCL3, BLK, BMP1, BMP8B, BMX, BOK, BRCA2, BRDT, DAGLA, CACNA1A, CACNB1, CACNB2, CACNB4, CALM3, CAMK2A, CAMK2G, CASP5, CASP9, CASP10, CASQ1, CASQ2, CD3D, CD3E, CD4, CD8A, CD9, CD28, TNFSF8, CD72, CDC20, CDH1, CEBPE, CEBPG, CENPF, CHN1, CHRNB2, CHUK, TBCB, AP2M1, AP2S1, CLCN2, CLN5, CNP, COL2A1, COL4A3, COL4A5, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, COL15A1, COL19A1, CR2, CRYAB, CSF2RB, CSNK2A1, CSNK2A2, CSPG4, CSRP2, CTF1, CTNND2, CYLC1, CYLC2, DAPK3, DAZ1, DBN1, DHCR7, DHFR, DIAPH2, DLD, DLG3, DNM1, DNASE1L3, DNMT1, DNMT3A, EPYC, DUSP5, DUSP7, DUSP9, TYMP, EDA, EFNA3, EFNA4, CELSR2, EIF2B1, ELAVL3, ELF1, ELK1, ELK3, EML1, CTTN, EMX2, EN1, EP300, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, ERF, ETV1, ETV3, ETV6, EXT2, FABP7, FANCG, FGF3, FGF4, FGF6, FGF7, FGR, FOXD1, FLOT2, FLT1, FSHB, FSHR, GABRA5, GABRB2, GDF9, GFRA1, GHRHR, GPC3, GLO1, GNAT1, GNAT2, GNGT1, GPLD1, GPM6B, GRB2, GRID2, GRIN2A, HIST1H1T, HEXB, HIP1, HMBS, HMGCR, NR4A1, HMX2, HOXD9, HPRT1, IFI16, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGF2, IL1A, IL2RB, IL2RG, IL10, ING2, ITGA1, ITGA9, KCNA1, KCNJ10, KIF5A, LLGL2, SMAD6, MAL, MARK3, RAB8A, ODF1, OGDH, OMP, OPHN1, PEX7, PEX13, PIP4K2A, PPP2R1A, PPP2R1B, PPP5C, PPT1, PRKAR1A, PRKCQ, PRKG1, PRM2, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PTPN6, PTPRA, PTPRR, PURA, PURB, RAB1A, RAB3A, RAC2, RAF1, RAP2A, RASA2, RFNG, RHAG, RNF2, RPGR, RPL22, RPL24, RPS3A, RPS6KA2, RPS6KB1, RPS19, RPS27A, RRAS, RYK, RYR1, S100A8, S100A9, SATB1, SCN5A, CCL21, SDC4, SFRP5, SGCD, ITSN1, SHB, SHC1, SIAH2, SIM2, SLC2A4, SLC8A3, SMARCA1, SMARCA2, SMARCA4, SMARCE1, SNAP25, SOS2, SPIB, SPTA1, SPTB, SRD5A1, SRPK2, SRY, STRN, TACC1, ADAM17, TAF4B, TARBP2, TBCE, NR2F1, TNFAIP2, TOP2A, TOP2B, TPD52, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TSPY1, TULP1, TULP3, TYK2, TYRO3, TYROBP, UBB, UBE2V1, UCP1, UGT8, KDM6A, VCL, YY1, ZIC1, ZNF3, ZNF217, ZP3, KCNAB1, SLC7A5, USP9X, PICALM, FZD8, FZD9, SOX14, LTBP4, FKBP6, CNTNAP1, KCNAB2, GAS7, PIR, RGS20, KLF7, UNC5C, PEA15, TNFSF12, DLK1, PEX11A, IL18R1, NRP2, EIF2B3, EIF2B2, RPS6KA4, RNF8, DYRK1B, DCLK1, VAPA, RPS6KA5, BCL7B, KL, NRXN3, NRXN1, EIF2AK3, PICK1, CHST3, PSMF1, TBPL1, NRG2, NR1D1, SPAG6, SOX13, FEZ2, ZNF516, CEP57, UTP14C, VPRBP, IFT140, FAM65B, SPOCK2, SPATA2, ARHGEF11, ZBTB24, GAB2, KIAA0196, WDR1, RBX1, REC8, NR2E3, HDAC6, BCL2L11, RANBP9, PTPRU, PQBP1, ARPC5, ARPC1B, ACTR3, ACTR2, ARL4A, FRY, RASA4, FARP1, WASF2, RNF41, PSME3, DHRS2, PSMD14, IRX5 |
1591 | GO:0007601 | 0.00 | 1.83 | 38.92 | 57 | 133 | visual perception | ABCA4, ARR3, BBS4, OPN1SW, CACNB2, CACNB4, CHRNB2, CNGA1, COL1A1, COL2A1, COL11A1, CRX, CRYBA1, CRYBA4, CRYGB, EYA4, EFEMP1, GABRR2, OPN1MW, GJA3, GLRA1, GLRB, GNAT1, GNAT2, GUCA1A, GUCY2F, GUCY2D, IMPG1, KCNJ10, OAT, OPA1, PAX2, PPT1, RABGGTA, RABGGTB, OPN1LW, RCVRN, PRPH2, RGR, RLBP1, RPGR, ATXN7, SFRP5, SIX3, NR2E1, TULP1, TULP2, TYR, CLRN1, WFS1, SOX14, RGS9, UNC119, SLC4A7, GUCA1C, NR2E3, IRX5 |
1592 | GO:1902679 | 0.00 | 1.83 | 188.47 | 270 | 644 | negative regulation of RNA biosynthetic process | ACVR2B, AEBP1, AES, NR0B1, AHR, ANXA4, BIRC5, ARNTL, ASCL1, ASCL2, ATF3, RERE, ATRX, BACH1, BCL3, PRDM1, BMI1, BMP4, KLF5, CAT, RUNX2, CD36, CDK5, CDX2, CEBPG, CENPF, CHD4, CMKLR1, CREB1, CRY2, DDX5, DNMT1, DNMT3A, DNMT3B, DRD3, ATN1, TSC22D3, E2F6, E4F1, EDNRB, EFNA1, EIF4A2, ELF3, ELK3, EN1, EP300, ERF, ETS2, ETV3, ETV6, FGF9, FGFR3, FOXD1, GATA3, GATA6, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, H3F3B, HBE1, HCLS1, HDGF, NRG1, HHEX, HIC1, HMGA1, FOXA2, HOXD8, HOXD9, HSBP1, HSF4, ID1, ID2, IFI16, IFNA2, IFNG, IGF1R, RBPJ, IRAK1, IRAK2, IRF1, ISL1, JARID2, JUN, JUNB, JUND, LMO1, SMAD3, SMAD7, MEN1, CIITA, TONSL, CNOT2, YBX1, ORC2, OVOL1, PA2G4, PAX2, PAX3, PAX9, CHMP1A, PEG3, PHB, PHF2, PIM1, PPID, PROX1, PSMC3, PSMC5, PTCH1, PTGIS, PTH, PURA, PURB, RARA, RARB, RB1, RBBP8, REST, RFX3, RNF2, RPS27A, RXRA, S100A1, SALL1, SATB1, XCL1, SET, SFPQ, SFRP5, SIAH2, SIM2, SIX3, SMARCA2, SMARCA4, SMARCE1, SNAI1, SNCA, SOX3, SOX5, SOX9, SOX10, SOX11, SP3, SP100, SREBF1, SRF, SRY, TRIM21, STAT3, STAT6, T, TAF7, TAL1, TBL1X, TBP, GCFC2, NR2F1, NR2F2, KLF10, NR2E1, TP73, NR2C1, TRPS1, TSG101, TNFSF4, UBB, UBE2D1, SUMO1, SCGB1A1, NR1H2, VDR, VEGFA, WFS1, WNT11, XRCC5, YY1, ZNF24, ZNF91, ZNF136, ZNF148, ZNF154, ZNF157, ZNF174, ZNF177, ZNF189, ZNF217, ZNF224, ZP3, LRP8, NRIP1, USP9X, KDM5C, ARID1A, HIST1H4I, CDC45, EOMES, FZD6, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NR0B2, CUL3, KLF11, HAT1, FCN3, TP63, EED, CREG1, SAP30, HESX1, PER3, TAX1BP1, HIST1H3F, HIST1H2AG, TAF1B, TAF1A, RNF8, UBA3, USP2, RGN, CBFA2T2, AURKB, RPS6KA5, KLF4, COPS2, RECQL5, HAND1, ZNF254, CIR1, NR1D1, CLOCK, PPM1F, PHF14, KDM4A, ST18, VPRBP, ZNF536, ZEB2, NR1I3, NR1H4, NR1D2, CASP8AP2, NR2E3, ZBTB33, HDAC6, ZNF263, YAF2, TRIM28, ZNF256, OLIG2, RAMP3 |
1593 | GO:0048589 | 0.02 | 1.83 | 16.97 | 25 | 59 | developmental growth | ANXA1, BCL9, BMPR1A, CCNE1, CHAT, DMBT1, GAS1, GATA3, GPX1, LIPC, SMAD3, PRKCQ, PTPN12, RAD51B, SALL1, SOX10, TBCE, TYMS, EIF4H, WNT11, FZD7, ADAM15, GINS1, TRIM28, SPRY1 |
1594 | GO:0008544 | 0.00 | 1.83 | 46.53 | 68 | 159 | epidermis development | ACVR1B, ALDH3A2, ALOX15B, ANXA1, STS, ATP2B2, BMP4, CST6, CTGF, CYP27B1, DBI, DCT, DNASE1L2, EDA, EPHA2, ELF3, ERCC3, EVPL, FGF7, FLOT2, GNAS, IGF1R, RBPJ, IVL, KRTAP5-9, KRT2, KRT5, KRT9, KRT14, KRT16, KRT31, KRT32, KRT34, KRT83, LAMA3, NTF4, OVOL1, REG3A, PTCH1, RAC1, RBP2, S100A7, SATB1, SNAI1, SOX9, SPRR2A, SPRR2D, SPRR2E, SPRR2G, SPRR3, ST14, TSG101, CLRN1, VDR, WAS, FZD3, IFT88, MADCAM1, FZD6, TP63, PTCH2, AKR1C3, TRADD, SCEL, LATS1, KLF4, SLC9A3R1, SLC4A7 |
1595 | GO:0015718 | 0.04 | 1.83 | 12.25 | 18 | 42 | monocarboxylic acid transport | ABAT, ALB, CACNA1A, CACNB4, AKR1C4, RXRA, SLC6A13, SLC10A1, SLCO1A2, TRH, TRPC4, SLC10A3, ABCC3, SLC5A6, SLC16A6, SLC16A5, SLC9A3R1, NR1H4 |
1596 | GO:0032388 | 0.00 | 1.83 | 55.52 | 81 | 190 | positive regulation of intracellular transport | ABL1, ACTL6A, ADCYAP1R1, ARF1, BAD, BAX, BDKRB1, BMP4, BMPR1A, CALM3, CASP8, CD4, CDH1, CDK5, CHRM1, CSNK2A2, CTSK, DNM1, EDA, EDNRA, EMD, F2, F2R, KAT2A, GPR26, HCLS1, NRG1, HNMT, IGF1, IL12B, IL18, JUP, KPNA1, IPO5, SMAD3, NTSR1, OAZ1, OAZ2, P2RX3, P2RX4, P2RX5, P2RX7, PCM1, PDPK1, PRKCQ, PSMB7, PSMD8, PTGS2, RAC2, RNASE2, RPL28, XCL1, SLC9A1, SNCA, SORL1, TRIP6, TRPC1, TRPC3, UBE2L3, YWHAH, YWHAZ, ZIC1, ZBTB17, FZD5, BAP1, RUVBL1, DYNLL1, TNFSF14, IL18R1, SYNJ1, CDKL2, ITGB1BP1, GSTO1, AKAP6, ATG13, C2CD5, FAM20B, BCL2L11, SAE1, TRIM28, NUTF2 |
1597 | GO:0006414 | 0.00 | 1.82 | 26.63 | 39 | 91 | translational elongation | EEF1B2, EIF5A, FAU, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, SRP9, TUFM, RPL14, RPL23, GTPBP1, EIF4A3 |
1598 | GO:1903531 | 0.00 | 1.82 | 26.63 | 39 | 91 | negative regulation of secretion by cell | ABAT, AGTR2, ANGPT1, ANXA1, ANXA4, ANXA5, BCR, CNR1, CRH, CRHBP, DRD3, F2R, FBLN1, GHSR, HMGCR, IFNA2, IL10, IL13RA2, TNFRSF9, INHA, INS, KCNJ11, PSMD9, PTGS1, RAP1A, REST, CX3CL1, SNCA, SREBF1, STXBP3, SYT4, TACR2, TRH, TNFSF4, SLC30A1, FGF23, VAMP8, CD84, NR1H4 |
1599 | GO:0007155 | 0.00 | 1.82 | 118.52 | 172 | 418 | cell adhesion | ACTB, ACTN1, AMBN, APP, RND3, ARHGAP5, ASTN1, ATP4B, AXL, BAX, BCL3, BGLAP, BMX, DST, ZFP36L2, BYSL, CASP8, RUNX2, CD7, CD8A, CD9, TNFSF8, SCARB1, SCARB2, CD58, CD72, ADGRE5, CD151, CDH6, CDH7, CDH8, CDH9, CDH10, CDH12, CDH15, CDK5, CCR1, CCR3, CCR8, COL4A3, COL4A6, COL6A1, COL6A2, COL6A3, COL15A1, COL19A1, COMP, CLDN3, VCAN, CSRP1, CTGF, CTNNA1, CTNND1, CTNND2, CX3CR1, CXADR, DSC3, EDA, ADGRE1, CTTN, EPHA4, EPHB1, FAP, FLT3, FPR2, B4GALT1, GNAS, GP1BA, GP9, RAPGEF1, GRID2, HAS1, HAS3, HSPB1, ICAM2, ICAM4, ID1, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, INS, INPPL1, ITGA1, ITGA7, ITGA9, ITGAD, ITGAE, ITGAM, ITGB5, JUP, KIT, SMAD6, MFGE8, KITLG, CD200, NRCAM, DDR2, OMD, OLR1, CLDN11, P2RX7, REG3A, PCDH7, PCDH8, PCDH9, PTPRS, PVR, RAB1A, RAB27A, RAG2, RAP2B, PRPH2, RPL22, S100A8, S100A9, SATB1, SELE, SELL, SELPLG, SHC1, SLAMF1, SIGLEC1, SOX4, SP3, SPAM1, SPG7, STAT6, STK10, STXBP3, CNTN2, ICAM5, TPBG, TRIP6, TYRO3, COL14A1, VCL, WAS, ZAN, FZD5, MADCAM1, EOMES, FZD8, SORBS2, CNTNAP1, STX11, CTNNAL1, SIGLEC5, IL18R1, NRP2, CD84, WISP3, PSTPIP1, CLDN12, CLDN10, CLDN8, CLDN6, CLDN1, SLIT2, NRXN3, NRXN1, NRXN2, BCAR1, SDC3, BCL2L11, GNE, TROAP, PTPRU, CHST4, GPA33, CD96 |
1600 | GO:0051248 | 0.00 | 1.82 | 188.76 | 270 | 645 | negative regulation of protein metabolic process | ABL1, ADAR, ANG, ANGPT1, APBB1, BIRC3, XIAP, BIRC5, APLP2, APP, AQP1, ATF3, ATF4, BAX, BCL3, BDKRB1, BMP4, BST2, BUB1, BUB1B, TSPO, C3, CALM3, CASP8, CAV3, CCNB1, CD44, CD59, CDC20, CDC27, CDK5, CDKN1A, CDKN2D, CENPF, CHAD, CIRBP, CLU, COL4A3, COL6A3, CR1, CRY2, CRYAB, CRYBA1, CSNK2A1, CSNK2A2, CST1, CST6, CD55, DAPK3, DCN, DDX3X, DLG2, DLG3, DNMT1, DNMT3B, DPEP1, DUSP1, DUSP5, DUSP7, DUSP9, ECM1, EDNRB, EIF4E, EIF4EBP2, SERPINB1, EPRS, F2, FBLN1, FGA, FLOT2, FYN, IFI6, GAPDH, GAS1, GHSR, GPC3, GNAQ, GP1BA, GPI, GPX1, GRB7, RAPGEF1, GRIN2A, HGF, NRG1, HHEX, HMGCR, HPN, HRG, DNAJB2, HSPB1, IFI16, IGF1, IGF1R, IGFBP3, IL10, ILK, INHA, INS, EIF3E, IREB2, ITGAV, ITIH1, ITIH2, ITIH4, JARID2, JUN, KNG1, LIMK1, CAPRIN1, MAD2L1, SMAD1, SMAD3, SMAD6, SMAD7, MEN1, CNOT2, NTRK3, OPHN1, P2RX7, SERPINE1, PAX2, SERPINA5, PCP4, PDPK1, SERPINF1, PHB, SERPINA4, SERPINB5, SERPINB6, SERPINB9, SERPINI1, SERPINB13, SERPINI2, PPP2R1A, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, DNAJC3, PROS1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTPN2, PTPN3, PTPN6, PTPRJ, PTPRR, PURA, PZP, RAF1, RAG1, RAN, RARA, RB1, RBM4, RENBP, UPF1, RPS3, RPS6KA1, RPS6KA3, RPS27A, SERPINB4, SET, SFTPD, SIAH2, SLPI, SMARCC1, SMPD1, SNCA, SNRNP70, SNTA1, SORL1, SOX4, SPINK1, SPOCK1, SRP9, TRIM21, TAF7, TARBP2, SERPINA7, NR2F2, TP73, TRAF2, TSC1, TTK, UBB, UBE2D1, USP4, NR1H2, VEGFA, VIL1, VTN, WNT1, ZNF207, AKAP1, PICALM, CUL3, OGT, PRKRA, EIF4EBP3, CDC23, SERPINB7, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, CDC16, EIF2B3, SOCS3, USP14, RGN, LATS1, ZW10, BUB3, ITGB1BP1, SOCS6, KLF4, TRIP12, SLIT2, SLC9A3R1, EIF2AK3, ATG5, PSMF1, TMEM59, BAG5, BAG4, GMFG, PPM1F, KDM4A, PUM1, RASSF2, EIF4A3, SFI1, RGP1, HDAC6, RANBP9, CTDSP2, FRY, FARP1, PSME3, PSMD14, PRG4, CTDSPL, SPRY1 |
1601 | GO:1903533 | 0.00 | 1.82 | 48.00 | 70 | 164 | regulation of protein targeting | ACTL6A, AGTR2, ANGPT1, BCL3, BMP4, BMPR1A, BNIP3L, CD36, CDH1, CDK5, CDKN1A, CSNK2A2, CTSK, EDA, EMD, KAT2A, GDI1, GNAQ, GPR26, HCLS1, NRG1, HNMT, IGF1, IL10, IL12B, IL18, JUP, KPNA1, IPO5, SMAD3, TONSL, PRDX1, PPM1B, PRKCQ, PSMB7, PSMD8, PTGS2, RAC2, RNASE2, RPL28, SFRP5, SLC9A1, SREBF1, TRIP6, UBE2L3, ZIC1, ZBTB17, FZD5, AKAP1, BAP1, FZD7, DYRK2, OGT, RGS20, RUVBL1, TNFSF14, IL18R1, CDKL2, ITGB1BP1, SLC9A3R1, AKAP6, CABP1, LITAF, BAG4, ATG13, C2CD5, FAM20B, SAE1, TRIM28, NUTF2 |
1602 | GO:0019221 | 0.00 | 1.82 | 36.80 | 54 | 129 | cytokine-mediated signaling pathway | ANGPT1, AXL, BAD, BBS4, CD74, CHAD, CSF1R, CSF2RB, DCN, ECM1, EIF4A1, EIF4A2, EIF4E, EIF4G2, EPOR, F3, FLT3, GP1BA, IFNW1, IL1A, IL1RAP, IL3, IL10RA, IL11RA, IL12B, IL12RB2, IL13RA2, IL15RA, KIT, KPNA1, KPNA2, KPNA3, KPNA4, NUP98, PPM1B, PTPRN, RANBP2, STAT3, STAT4, STAT5B, UBA7, LRP8, IL1R2, NUP214, AAAS, EIF4G3, RIPK2, IL18R1, IL1RL1, SOCS6, IL27RA, NUP155, NUP93, EIF4A3 |
1603 | GO:0001841 | 0.01 | 1.82 | 18.44 | 27 | 63 | neural tube formation | APAF1, BBS4, BMP4, CASP8, FZD2, KAT2A, OPA1, PAX2, PAX3, PRKACB, PTCH1, RALA, RARA, SALL1, SDC4, STIL, SOX4, SOX11, ST14, T, TSC1, TULP3, KDM6A, FZD3, ARID1A, FZD6, ZEB2 |
1604 | GO:0035113 | 0.01 | 1.82 | 18.44 | 27 | 63 | embryonic appendage morphogenesis | ALX3, BAX, BMP4, BMPR1A, RUNX2, DLX5, EN1, FGF4, FGF8, FGF9, GPC3, GNAQ, GNAS, HOXC10, HOXC11, HOXD9, HOXD10, HOXD12, IHH, PTCH1, RARB, SALL1, TULP3, IFT88, FZD6, TP63, BCL2L11 |
1605 | GO:0048524 | 0.02 | 1.82 | 16.39 | 24 | 56 | positive regulation of viral process | ADAR, CD28, DDB1, DDX3X, EP300, ERCC3, NR5A2, HPN, IFIT1, JUN, PPIB, PPID, SMARCA4, SP1, SRPK2, TRIM21, SSRP1, STAU1, TARBP2, TOP2A, TSG101, CTDP1, VAPB, VAPA |
1606 | GO:0051049 | 0.02 | 1.82 | 16.21 | 24 | 59 | regulation of transport | ABCA2, ARG1, ATP1A1, ATP4A, CAMK2G, CRY2, GFAP, HK2, PPP1R12A, NUP98, RANBP2, RBM4, RCVRN, RPS6KB1, RTN2, SCNN1B, SLC9A3, TNNC1, TRPC4, NUP214, AAAS, INPP4B, NUP155, NUP93 |
1607 | GO:2000027 | 0.00 | 1.82 | 28.07 | 41 | 96 | regulation of organ morphogenesis | ABL1, ABL2, AGTR2, BMP4, BMPR1A, CAV3, RUNX2, CHAD, EDNRA, CELSR2, ETV4, ETV5, GPC4, FGF3, FGF7, FGF8, FZD2, GATA3, GDNF, HGF, HOXC11, HPN, IFNG, RBPJ, ISL1, PAX2, PAX9, PTN, RAC1, RXRA, RYK, SALL1, SOX9, VEGFA, WNT11, FZD3, IFT88, FZD6, FZD7, NUMB, SPRY1 |
1608 | GO:1903362 | 0.00 | 1.82 | 33.57 | 49 | 115 | regulation of cellular protein catabolic process | ARAF, CAV3, CLU, CSNK1D, PTK2B, GPX1, UBE2K, DNAJB2, SMAD7, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, RAD23B, RB1, RPS27A, SKP1, SUMO3, UBB, UBE3A, SUMO1, CUL3, CUL1, RGN, RNF14, DLGAP5, RNF40, PSME3, PSMD14 |
1609 | GO:0006950 | 0.02 | 1.81 | 13.98 | 21 | 56 | response to stress | ACADS, ACAT1, ADH5, NR0B1, CPS1, CYP1A2, DHODH, TSC22D3, GCG, GCGR, HNMT, KCNJ11, OXCT1, OXTR, PCP4, SORD, TACR3, SLC30A1, SLC14A2, SNN, EIF1 |
1610 | GO:0032990 | 0.00 | 1.81 | 192.28 | 274 | 657 | cell part morphogenesis | ABL1, ABL2, ACTB, ADAM10, ADCY1, AP2B1, ANGPT1, APBB1, APBB2, APP, ARAF, ARHGAP4, RERE, BAX, BBS4, BCL2L1, BMPR2, CACNA1A, CACNB1, CACNB2, CACNB4, CALM3, CAMK2A, CAMK2G, CD72, CDK5, CHN1, CHRNB2, AP2M1, AP2S1, CLU, CNP, COL2A1, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2, CSF2RB, CSNK1D, CSNK2A1, CSNK2A2, CTNND2, DCC, DLG3, DLX5, DNM1, DNM2, DPYSL3, EPYC, DUSP5, DUSP7, DUSP9, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EFNB2, CELSR2, EGR2, EPHA2, EMX1, CTTN, EPHA3, EPHA4, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, ETV1, ETV4, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FYN, GATA3, GDI1, GDNF, GFRA1, GOLGA4, GPC1, GPM6A, GRB2, GRIN2A, NRG1, ONECUT1, HPRT1, ID1, IL2RA, IL2RB, IL2RG, IL3, ILK, ISL1, ITGA1, ITGA2, ITGA5, ITGA9, ITGAV, ITGB1, KIF5A, KIT, LIMK1, CAPRIN1, MAP1B, MARK3, RAB8A, KITLG, NRCAM, NTF4, NTRK2, NTRK3, NTN3, OCRL, OPHN1, OTX2, PAX2, PCM1, PPP5C, PRKCQ, MAPK1, MAPK3, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, PTPRA, PTPRZ1, RAB3A, RAC1, RAC2, RAF1, RAP2A, RASA2, RET, RFX3, RFX4, RNF6, RPGR, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RRAS, RYK, SCN5A, SEMA3F, SGK1, ITSN1, SHC1, SIAH2, STIL, SNX2, SOS2, SPTA1, SPTB, SRF, SUPV3L1, SYT1, SYT4, CNTN2, TBCE, DYNLT1, NR2E1, TNR, TOP2B, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TYROBP, UBB, UGT8, VCL, VEGFA, VIL1, YWHAH, LRP8, SEMA3B, FZD3, FGF23, IFT88, RND2, USP9X, PICALM, CUL3, SEMA7A, CNTNAP1, GAS7, KLF7, UNC5C, NUMB, DYNLL1, PEA15, IQGAP1, NRP2, NRP1, AKAP4, ARHGEF7, PHOX2B, RPS6KA4, ATP6V0D1, ARHGEF1, DCLK1, RPS6KA5, SNAP29, SLIT2, KL, NRXN3, NRXN1, ATG5, ONECUT2, PSMF1, NRG2, AATK, FEZ2, RAPGEF2, RIMS2, SEMA3E, IFT140, KIAA0586, CUL7, ARHGEF11, RBX1, RANBP9, PQBP1, COL4A3BP, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, AKAP9, RASA4, FARP1, WASF2, PSME3, PSMD14, ABCC4 |
1611 | GO:0002274 | 0.03 | 1.81 | 13.68 | 20 | 47 | myeloid leukocyte activation | ADAM10, BPI, CD86, CD37, CD74, CLU, CNR1, CSF2, FLT3LG, RBPJ, IL10, JUN, PTPRE, S100A12, CX3CL1, SNCA, TRPV1, TNFSF9, IL1RL1, DHRS2 |
1612 | GO:0031327 | 0.00 | 1.81 | 42.45 | 62 | 150 | negative regulation of cellular biosynthetic process | ACVRL1, ADAR, ANG, ATF4, ATP1A1, ATR, BMPR2, BRCA2, TSPO, CACNA1A, CDC6, CIRBP, CYP27B1, DAPK3, DDX3X, DUSP1, LPAR1, EDNRA, EIF4E, EIF4EBP2, EPRS, GALR1, GAPDH, GHSR, GNAI3, GRB7, HNRNPC, IL10, INHA, INS, INSIG1, EIF3E, IREB2, KCNK2, CAPRIN1, SMAD1, PALM, PRKAA1, RAN, RBM4, UPF1, RPS3, S100A11, SFTPD, SRP9, TARBP2, TSC1, TTF1, SMC1A, PRKRA, EIF4EBP3, AKR1C3, EIF2B3, SMC3, EIF2AK3, AKAP6, TMEM59, GABBR2, RAPGEF2, PUM1, EIF4A3, PRG4 |
1613 | GO:1901606 | 0.02 | 1.81 | 17.84 | 26 | 61 | alpha-amino acid catabolic process | AHCY, ARG1, ASL, ASPA, ALDH7A1, AUH, BCAT2, CDO1, DAO, DLD, GAD1, GLDC, GLUD1, GOT2, GPT, HNMT, IDO1, IVD, OAT, OGDH, PAH, QDPR, SHMT1, DDO, ALDH4A1, KYNU |
1614 | GO:0090288 | 0.02 | 1.80 | 17.85 | 26 | 61 | negative regulation of cellular response to growth factor stimulus | ABL1, AGTR2, DCN, DNM2, FBN1, GATA3, GPC1, HHEX, ONECUT1, HRG, SMAD3, SMAD6, SMAD7, PDPK1, PPP1CA, RPS27A, ADAM17, UBB, WNT1, CHRD, SLIT2, ZFYVE9, ONECUT2, ADAMTSL2, PDCD6, SPRY1 |
1615 | GO:1903650 | 0.02 | 1.80 | 17.85 | 26 | 61 | negative regulation of cytoplasmic transport | ANGPT1, BARD1, CALM3, CASQ2, CD36, CDK5, EMD, IL10, INSIG1, TONSL, NTSR1, PLN, PPM1B, RANGAP1, SFRP5, SOX4, SP100, TRIP6, AKAP1, DYRK2, TNFSF14, SLC9A3R1, GSTO1, CABP1, LITAF, BAG4 |
1616 | GO:0051346 | 0.00 | 1.80 | 69.95 | 101 | 239 | negative regulation of hydrolase activity | ABL1, ANXA1, BIRC3, XIAP, BIRC5, APLP2, APP, AQP1, ARL2, BBS4, BICD1, BST2, C3, CASP8, CD44, CDKN2D, CNN3, COL4A3, COL6A3, CR1, CRY2, CRYAB, CSNK2A1, CST1, CST6, DDX3X, DLG2, DLG3, DPEP1, ECM1, SERPINB1, IFI6, GPC3, GNAT1, GPI, GPX1, HGF, HPN, HRG, IFI16, IFIT1, ITIH1, ITIH2, ITIH4, KNG1, IPO5, LTF, SERPINE1, PAX2, SERPINA5, SERPINF1, SERPINA4, SERPINB5, SERPINB6, SERPINB9, SERPINI1, SERPINB13, SERPINI2, PLN, PROS1, PTPRN2, PZP, RAF1, RAG1, RENBP, RPS6KA1, RPS6KA3, SORT1, SERPINB4, SIAH2, SLPI, SNCA, SORL1, SPINK1, SPOCK1, SERPINA7, TNNI3, TRAF2, VEGFA, VIL1, VTN, PICALM, SERPINB7, TRADD, RIPK1, TNFSF14, TNFSF10, TNFRSF10B, TNFRSF10A, IQGAP1, USP14, RGN, DGKI, KLF4, SLIT2, PSMF1, BAG4, SFI1, RASA4, FARP1, SPRY1 |
1617 | GO:0002460 | 0.02 | 1.80 | 17.18 | 25 | 59 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | BTK, C7, CD8A, CD74, CLC, CLU, CR1, CR2, CTSH, CD55, EMP2, GATA3, ICAM1, IFNA2, IL10, IL13RA2, PTPN6, RAB27A, ADAM17, WAS, KDM5D, STX11, TNFSF18, RNF8, EXO1 |
1618 | GO:0045859 | 0.05 | 1.80 | 11.62 | 17 | 41 | regulation of protein kinase activity | APLP2, APP, CCNE1, CDC25A, CDC25C, CDK4, CKS1B, FGR, PRKAB2, RAC2, RAP2B, TSC1, TSG101, UVRAG, IKBKAP, DIRAS3, SLC9A3R1 |
1619 | GO:0030097 | 0.00 | 1.80 | 61.47 | 89 | 213 | hemopoiesis | ABL1, ABL2, ACTN1, ADAR, ADD1, ALAS2, ANGPT1, BAX, BCL3, BMI1, BMX, BRCA2, ZFP36L2, CASP9, CASP10, RUNX2, CD3D, CD3E, CD4, CD8A, TNFSF8, CEBPE, CEBPG, CHUK, CR2, CSF2, EPHA2, EML1, EP300, ETV2, ETV6, GPC3, GLO1, HHEX, ONECUT1, IFI16, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, RBPJ, IL10, ITGA4, ITGB1, JUNB, PIP4K2A, PRKX, PTPRZ1, RAG2, REST, RHAG, RPL22, RPS19, RRAS, SATB1, SLC8A3, SOX4, SP1, SP3, SPTA1, SPTB, STAT6, ADAM17, TAZ, TOP2A, TPD52, TSC1, TYRO3, WNT1, FZD5, PICALM, EOMES, FZD7, FZD8, FZD9, GFI1B, KCNAB2, PIR, IL18R1, ARHGEF7, SGPL1, KLF4, VPRBP, ZBTB24, GAB2, WASF2, DHRS2, PRG4 |
1620 | GO:0061572 | 0.01 | 1.80 | 23.41 | 34 | 80 | actin filament bundle organization | ABL2, ACTN4, ACTN1, ADD1, ARHGAP6, BBS4, CTGF, DPYSL3, S1PR1, LPAR1, PTK2B, ID1, ITGB5, LIMK1, SMAD3, MYO1B, PFN2, PRKCQ, RAC1, SDC4, SLC9A1, FSCN1, SRF, HSP90B1, TSC1, VIL1, WNT11, ARHGEF5, CUL3, GAS7, ITGB1BP1, BAG4, PPM1F, WASF2 |
1621 | GO:0034763 | 0.04 | 1.80 | 13.75 | 20 | 47 | negative regulation of transmembrane transport | ATP1A2, CALM3, CASQ2, CAV3, DRD3, KCNH2, KCNQ1, NTSR1, OAZ1, OAZ2, PIK3C2A, PLN, PRKCE, SPINK1, SUMO1, SLC30A1, KCNAB1, SLC9A3R1, GSTO1, OXSR1 |
1622 | GO:0045165 | 0.02 | 1.80 | 17.19 | 25 | 59 | cell fate commitment | PRDM1, RUNX2, ETS2, FGF8, FGFR3, GAS1, GATA4, NRG1, ONECUT1, ID2, IL12B, KDR, SMAD1, PAX3, RAG2, RARA, SOX5, STAT6, TAL1, NR2E1, TRPS1, WNT11, TNFSF18, LATS1, ONECUT2 |
1623 | GO:0006024 | 0.01 | 1.79 | 21.36 | 31 | 73 | glycosaminoglycan biosynthetic process | ANGPT1, CLTC, VCAN, CSPG4, DCN, EXT2, EXTL1, EXTL3, GPC4, GPC5, B4GALT1, GPC3, GPC1, HAS1, HAS2, HAS3, HEXA, IGF1, OMD, SDC1, SDC4, B4GALT4, B4GALT3, B4GALT6, CHST3, HS2ST1, SDC3, HS3ST3B1, HS3ST1, ABCC5, UST |
1624 | GO:0006733 | 0.01 | 1.79 | 21.36 | 31 | 73 | oxidoreduction coenzyme metabolic process | ALDOC, ARNT, BPGM, DLD, ENO2, GAPDH, GPI, HK2, HMGCR, IDH1, IGF1, INS, MDH2, OGDH, P2RX7, PFKFB4, PGAM1, PGD, PGK2, PPP2R5D, PRKAA1, PRKAG1, PTGIS, PTGS2, RPE, STAT3, PDHX, OGT, KCNAB2, KYNU, TP53I3 |
1625 | GO:0051094 | 0.00 | 1.79 | 28.12 | 41 | 100 | positive regulation of developmental process | AGTR2, ADGRB2, CBLB, CD3E, CD28, CD40, CDC20, DCN, EDNRA, EPHB1, EPHB2, EPHB3, FGF3, FGF7, FOXD1, GPM6B, HMGCR, HMGA1, HOXC11, HPN, IDO1, OTX2, OXTR, P2RX7, PRKAA1, PTH, SLC8A1, SRY, STAT6, TPBG, UNG, WNT1, TRADD, TNFSF13, USP2, KL, NRXN3, NRXN1, RBM19, RNF10, SPRY1 |
1626 | GO:0071310 | 0.00 | 1.79 | 40.02 | 59 | 155 | cellular response to organic substance | ABL2, ADD1, ATF3, ATF4, BAX, PRDM1, TSPO, CD6, CD9, CD14, CD36, SCARB1, CEBPE, TPP1, CTH, CD55, BRINP1, DDX11, LPAR1, EDNRB, EFNA5, EGR2, SLC29A1, EPHA3, EPHA5, EXTL3, HDGF, HMGCR, FOXA2, KRT13, LTF, ATXN3, OXCT1, DNAJC3, PSAP, PTPRN2, RET, SLC2A5, SOX4, SRF, SULT1A3, SYP, UFD1L, WFS1, WNT11, ZNF16, ZNF35, ZBTB17, FZD7, VAPB, RAB11B, HMGN3, NRXN1, EIF2AK3, LITAF, GOSR2, TATDN2, CUL7, CTDSP2 |
1627 | GO:0051783 | 0.03 | 1.79 | 15.17 | 22 | 52 | regulation of nuclear division | BIRC5, CD28, CDC6, CDC25C, CENPE, DAPK3, DRD3, FGF8, GPR3, IGF1, IGF1R, IGF2, IL1A, INS, CHMP1A, PTEN, RB1, CUL3, MAD2L1BP, KNTC1, DLGAP5, CUL7 |
1628 | GO:0031345 | 0.01 | 1.79 | 24.88 | 36 | 85 | negative regulation of cell projection organization | ARHGAP4, CDK5, DCC, DPYSL3, LPAR1, EFNA1, EPHA4, EFEMP1, GDI1, GFAP, HRG, ID1, ITGB1, PFN2, PTEN, PTK2, PTPRZ1, RAP1GAP, RNF6, CCL21, SEMA3F, SPOCK1, TNR, VIM, YWHAH, SEMA3B, NRP1, ARHGEF1, CBFA2T2, SLIT2, NRXN1, BAG5, AATK, RAPGEF2, SEMA3E, KIAA0319 |
1629 | GO:0045732 | 0.00 | 1.78 | 46.53 | 67 | 159 | positive regulation of protein catabolic process | ADAM8, BARD1, CAV3, CBLB, CCNB1, CDC20, CDC27, CLU, CSNK1D, CSNK2A1, PTK2B, GPC3, GPLD1, DNAJB2, IFNG, SMAD7, ATXN3, OAZ1, OAZ2, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, RB1, RPS27A, SKP1, SUMO3, SORL1, SOX9, TNFRSF1B, UBB, UBE2D1, SUMO1, VIP, CUL3, CUL1, CDC23, TNFSF12, CDC16, RGN, PSMF1, SEC22B, RNF14, DLGAP5, RNF40, PSME3, PSMD14 |
1630 | GO:0042278 | 0.00 | 1.78 | 50.04 | 72 | 171 | purine nucleoside metabolic process | ACACB, ACPP, ADA, ADSS, AHCY, AK1, AK2, ALDOC, AMPD2, APRT, ARNT, ATP1A2, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V0A1, BAD, BPGM, TSPO, COX8A, COX15, CTNS, DLD, DLG2, DLG3, DNMT1, DNMT3A, DNMT3B, ENO2, GAPDH, GNAI3, GPI, GUK1, HK2, HMGCR, HPRT1, IGF1, IMPDH1, IMPDH2, INS, LDHC, OGDH, P2RX7, PFKFB4, PGAM1, PGK2, PPP2R5D, PRKAA1, PRKAG1, PRPS2, PTGDR, SDHC, SNCA, STAT3, SULT1E1, SULT1A3, SULT1C2, SULT2B1, TAZ, UQCRC1, UQCRC2, UQCRH, OGT, PAPSS1, COX5A, SLC25A13 |
1631 | GO:0016331 | 0.01 | 1.78 | 26.34 | 38 | 90 | morphogenesis of embryonic epithelium | ALDH1A3, APAF1, BBS4, BMP4, CASP8, FGF8, FZD2, GATA3, KAT2A, GDNF, HHEX, LLGL2, OPA1, PAX2, PAX3, PCDH8, PRKACB, PTCH1, RALA, RARA, RET, SALL1, SDC4, STIL, SOX4, SOX9, SOX11, ST14, T, TSC1, TULP3, KDM6A, FZD3, ARID1A, FZD6, TP63, HAND1, ZEB2 |
1632 | GO:1903828 | 0.01 | 1.78 | 20.78 | 30 | 71 | negative regulation of cellular protein localization | ANGPT1, BARD1, BCL2L1, CAV3, CD36, CDK5, AP2M1, CLTC, EMD, GDI1, GPM6B, IL10, TONSL, PPM1B, RANGAP1, SFRP5, SOX4, SP100, TRIP6, AKAP1, DYRK2, OGT, NUMB, TNFSF14, ITGB1BP1, SLC9A3R1, CABP1, LITAF, TMEM59, BAG4 |
1633 | GO:0006796 | 0.00 | 1.77 | 157.24 | 224 | 575 | phosphate-containing compound metabolic process | ACACB, ADA, ADAM10, ADRBK1, ADSS, AK1, AK2, ALDOC, AMPD1, AMPD2, BIRC5, APRT, AQP1, ATP1A2, ATP2B2, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V0A1, ATR, AXL, BCR, BLK, BMX, BTK, BUB1, BUB1B, CACNB4, CAT, ENTPD2, CDK11B, CDK2, CDK3, CDK6, CDK8, CHAT, CHEK1, CHKA, CHKB, CHUK, CKM, CLK1, CLK3, CNP, COX8A, COX15, CPS1, CREB1, CRYAB, CSNK1G3, CSNK2A1, CSNK2A2, CTNS, CTSG, CTSH, DGKB, DAPK3, DBI, DHFR, DHODH, DLD, TYMP, ELK1, ENO2, EPHA3, EPHA5, EPHB2, EPHB3, ERCC3, ERG, EFEMP1, FDFT1, FDPS, FYB, GALK2, GAPDH, GARS, GATA6, GK2, GPD2, GPI, GPX1, GUCY2C, GUCY2F, GUK1, GUCY2D, HADHA, HEXB, HK2, HPRT1, IL12RB2, IMPDH1, IMPDH2, INSRR, ITGAV, KCNH2, LCAT, LDHC, LIMK1, LIMK2, LIPC, LIPE, SMAD1, SMAD9, MDH2, CIITA, NUDT1, NTHL1, OAS1, OGDH, OXTR, PCYT1A, PDE4B, PDE8A, PDK4, PFAS, PGD, PGK2, PHKA2, PHKB, PHKG1, PIK3C2A, PIK3C2B, PI4KA, PIP4K2A, PRKCB, PRKCI, PRKCQ, PRKG1, PRKX, PRPS2, PSKH1, PTGIS, PTGS2, RARA, RBM4, RPE, RPS6KA1, RPS6KA2, RPS6KA3, RPS6KB1, RPS6KB2, RRM1, RRM2, SDHC, SGK1, SHMT1, SKP1, SLC20A1, SORD, SRPK2, STAT4, SULT1E1, SULT1A3, SULT1C2, SULT2B1, TAZ, TOP1, NR2C2, TRIO, TYK2, TYMS, TYRO3, UNG, UPP1, UQCRC1, UQCRC2, UQCRH, VRK1, SCG2, PDHX, DYRK2, CUL1, KCNAB2, DGKE, PRKRA, STK16, TNKS, DGAT1, RIOK3, DYRK4, SUCLG1, CDKL1, DPM2, MBD4, KYNU, CDKL2, BAZ1B, PAPSS1, DYRK1B, DGKI, DCLK1, AURKB, STK17B, STK17A, COX5A, LIPG, GGPS1, PICK1, PIGL, TBPL1, TP53I3, CDC42BPB, ENTPD4, AATK, VPRBP, PTDSS1, FAM20B, XYLB, GNE, PIGK, SH2D3C, SH2D3A, COL4A3BP, SGK2, ABI2, TRIM28, SLC25A13 |
1634 | GO:0015850 | 0.00 | 1.77 | 31.22 | 45 | 107 | organic hydroxy compound transport | ABAT, ABCA1, ABCA2, ADRBK1, AGTR1, AGTR2, ALB, AQP1, AQP5, AQP6, TSPO, CD36, SCARB1, AKR1C4, CHRNB2, CLU, CNR1, DRD3, GALR1, GDNF, FFAR3, LCAT, LIPC, OSBP, OXTR, PCP4, PTCH1, PTGS1, RAB3B, RXRA, SEC14L1, SLC6A2, SLC10A1, SLCO1A2, SLC22A1, SLC22A3, SLC22A2, NR1H2, SLC10A3, ABCC3, SLC16A6, SLC16A5, SLC9A3R1, LIPG, NR1H4 |
1635 | GO:0007586 | 0.01 | 1.77 | 24.29 | 35 | 83 | digestion | AQP1, AQP5, CD36, SCARB1, CHRM1, CHRM3, CLPS, COPA, CRH, CTRB1, CTSE, ACE, DRD3, ENPEP, FABP2, GALR1, GHSR, KCNN4, KCNQ1, LIPC, OXTR, P2RX7, PGA5, SCTR, SGK1, SLC15A1, SLC22A5, SOX9, TRPC1, NR1H2, VDR, VIL1, TRPV1, MGAM, LIPG |
1636 | GO:0006029 | 0.02 | 1.77 | 18.73 | 27 | 64 | proteoglycan metabolic process | BMPR2, COL2A1, COL11A1, VCAN, CSPG4, DCN, EXT2, EXTL1, EXTL3, GPC4, GPC5, GPC3, GPC1, HEXA, HEXB, IDS, IDUA, IGF1, IHH, LIPC, SDC1, SDC4, CHST3, SDC3, SPOCK2, HS3ST3B1, UST |
1637 | GO:0050680 | 0.02 | 1.77 | 18.73 | 27 | 64 | negative regulation of epithelial cell proliferation | ACVRL1, APOH, BMP4, BRCA2, KLF9, KRIT1, CDK6, EFNB2, ETV4, GATA3, GPC3, HPN, KRT4, MEN1, SERPINF1, PTCH1, PTEN, PTN, RAP1GAP, RB1, SOX9, SPARC, NR2F2, VDR, SCG2, IFT88, RGN |
1638 | GO:0072006 | 0.02 | 1.77 | 18.73 | 27 | 64 | nephron development | ACAT1, ACTA2, AGTR2, ANGPT1, ANGPT2, AQP1, BMP4, CD44, COL4A3, ENPEP, FGF8, FOXD1, GATA3, GDNF, GPC3, ILK, PAX2, PSPN, PTCH1, RET, SALL1, SOX9, VEGFA, WNT1, WNT11, SERPINB7, IQGAP1 |
1639 | GO:0045934 | 0.00 | 1.77 | 216.86 | 304 | 741 | negative regulation of nucleobase-containing compound metabolic process | ACVR2B, ACVRL1, AEBP1, AES, NR0B1, AHR, ANXA4, BIRC5, ARNTL, ASCL1, ASCL2, ATF3, RERE, ATR, ATRX, BACH1, BARD1, BCL3, PRDM1, BMI1, BMP4, BMPR2, BRCA2, KLF5, TSPO, CAT, RUNX2, CD36, CDA, CDC6, CDK5, CDX2, CEBPG, CENPF, CHD4, CMKLR1, CREB1, CRY2, DDX5, DFFA, DNMT1, DNMT3A, DNMT3B, DRD3, ATN1, TSC22D3, DUSP1, E2F6, E4F1, LPAR1, EDNRA, EDNRB, EFNA1, EIF4A2, ELF3, ELK3, EN1, EP300, ERCC4, ERF, ETS2, ETV3, ETV6, FGF9, FGFR3, FOXD1, GALR1, GATA3, GATA6, GNAI3, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, H3F3B, HBE1, HCLS1, HDGF, NRG1, HHEX, HIC1, HMGA1, FOXA2, HNRNPC, HOXD8, HOXD9, HSBP1, HSF4, ID1, ID2, IFI16, IFNA2, IFNG, IGF1R, RBPJ, IRAK1, IRAK2, IRF1, ISL1, JARID2, JUN, JUNB, JUND, KCNK2, LMO1, SMAD3, SMAD7, MEN1, CIITA, TONSL, CNOT2, YBX1, ORC2, OVOL1, PA2G4, PALM, PAX2, PAX3, PAX9, CHMP1A, PEG3, PHB, PHF2, PIM1, PPID, PROX1, PSMC3, PSMC5, PTCH1, PTGIS, PTH, PURA, PURB, RARA, RARB, RB1, RBBP8, REST, RFX3, RNF2, RPS3, RPS26, RPS27A, RXRA, S100A1, S100A11, SALL1, SATB1, XCL1, SET, SFPQ, SFRP5, SRSF7, SFSWAP, SIAH2, SIM2, SIX3, SMARCA2, SMARCA4, SMARCE1, SNAI1, SNCA, SOX3, SOX5, SOX9, SOX10, SOX11, SP3, SP100, SREBF1, SRF, SRY, TRIM21, STAT3, STAT6, T, TAF7, TAL1, TBL1X, TBP, GCFC2, NR2F1, NR2F2, KLF10, NR2E1, TP73, NR2C1, TRPS1, TSG101, TTF1, TNFSF4, UBB, UBE2D1, SUMO1, SCGB1A1, NR1H2, VDR, VEGFA, WFS1, WNT11, XRCC5, YY1, ZNF24, ZNF91, ZNF136, ZNF148, ZNF154, ZNF157, ZNF174, ZNF177, ZNF189, ZNF217, ZNF224, ZP3, LRP8, NRIP1, USP9X, KDM5C, SMC1A, ARID1A, HIST1H4I, CDC45, EOMES, FZD6, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NR0B2, CUL3, KLF11, HAT1, FCN3, TP63, TNKS, SRSF9, EED, CREG1, SAP30, HESX1, PER3, TAX1BP1, HIST1H3F, HIST1H2AG, TAF1B, TAF1A, RNF8, UBA3, USP2, RGN, SMC3, CBFA2T2, AURKB, RPS6KA5, KLF4, COPS2, TRIP12, RECQL5, HAND1, AKAP6, ZNF254, CIR1, GABBR2, NR1D1, CLOCK, PPM1F, PHF14, KDM4A, DHX34, ST18, VPRBP, ZNF536, RNF40, ZEB2, NR1I3, NR1H4, NR1D2, CASP8AP2, NR2E3, ZBTB33, HDAC6, RAD50, ZNF263, YAF2, TRIM28, ZNF256, OLIG2, RAMP3 |
1640 | GO:0051641 | 0.00 | 1.77 | 99.74 | 143 | 364 | cellular localization | ABCA1, ACACB, ACTN1, ACVR2B, AGTR1, ABCD1, ANXA3, APP, AQP1, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, KIF1A, AXL, BGLAP, VPS51, CACNA1B, CACNG1, SLC25A20, CAMK2G, CD9, CDX2, CHAT, CLCN3, CLU, CCR1, CNP, CPT1B, CPT2, SLC25A10, CTGF, CD55, EIF4E, EPS15, EYA2, F7, F10, FTL, GAA, GAD1, GCGR, GLE1, GOLGB1, XCR1, HGF, HRG, IGF2, RBPJ, IL1RN, KCNJ10, KIF5A, KNG1, LAMP2, MYO1B, P2RX1, SERPINE1, PCSK5, PIK3C2A, PPT1, PRKAB2, PROC, PROS1, PSAP, PTPRN, PTPRN2, RAB5B, RAF1, RANBP1, UPF1, RYR1, SORT1, S100A12, CCL21, SELP, SET, SRSF1, SRSF5, SRSF7, SLC1A6, SLC6A4, SLC6A13, SLC8A3, SLC22A2, SPARC, SPG7, SPTA1, SPTB, HNF1A, TSC1, TUBA4A, TYRO3, UCP1, VDAC1, VEGFB, VIP, TRPV1, WAS, WRN, TUBA1A, SCG2, ANP32A, SYN3, PICALM, FZD4, EEA1, LTBP4, SLC25A12, SRSF9, PROZ, SLC25A14, SEC22C, DGKI, DCLK1, NRXN3, COG1, VPS26A, CLINT1, PUM1, USP6NL, DHX38, SCRN1, RGP1, DNAJC6, ZC3H11A, SMG7, SGSM2, RBM8A, WDR1, GOLGA5, HMGXB4, SCAMP2, ATP9A, COL4A3BP, SLC25A13, SLC25A15, ALYREF, RABEPK, ABCC4 |
1641 | GO:0051050 | 0.01 | 1.76 | 25.63 | 37 | 90 | positive regulation of transport | ABCA1, ANXA1, ATP2B2, TSPO, CACNB2, CAMK2A, CCR1, CTSS, DPP6, FFAR3, KCNC2, KCNH2, KCNJ2, KCNJ11, KCNQ1, P2RX1, PRKCI, PRSS8, PTCH1, PTH, RYR2, S100A1, SCN4B, SCN5A, SGK1, SLC34A1, STC1, SUMO1, WFS1, CLTCL1, PIK3R3, RGN, SYNGR3, LIPG, AKAP7, SGK2, AKAP9 |
1642 | GO:0051169 | 0.00 | 1.76 | 72.87 | 104 | 249 | nuclear transport | ADAR, AGTR2, ANGPT1, ARNTL, RERE, BARD1, BCL3, BMP4, BMPR1A, CBLB, CD36, CDH1, CDK5, CDKN1A, CSE1L, EDA, EGR2, EIF4E, EIF5A, EMD, F2R, FGF9, FYB, GLE1, GNAQ, HCLS1, HHEX, HSPA9, IFNG, IGF1, IL10, IL12B, IL18, EIF6, JUN, JUP, KPNA1, KPNA2, KPNA3, KPNA4, IPO5, SMAD3, PPP1R12A, TONSL, NUP98, PRDX1, PPM1B, PRKCQ, MAPK1, MAPK3, PTGS2, PTPN14, RAN, RANBP2, RANGAP1, RBM4, UPF1, SET, SFRP5, SRSF1, SRSF5, SRSF7, SIX3, SLC9A1, SOX4, SP100, STAT3, STYX, SYK, DYNLT1, TRIP6, TRPS1, TSC1, WRN, ZIC1, NUP214, AAAS, ANP32A, AKAP1, FZD7, DYRK2, RGS20, AKR1C3, SRSF9, TNFSF14, IL18R1, INPP4B, RPL23, SLC9A3R1, ZFYVE9, AKAP6, CABP1, LITAF, NUP155, IPO13, NUP93, CEP57, DHX38, ZC3H11A, SMG7, RBM8A, TRIM28, ALYREF, NUTF2 |
1643 | GO:0031400 | 0.00 | 1.76 | 104.19 | 148 | 356 | negative regulation of protein modification process | ABL1, ADAR, ANGPT1, ATF3, BAX, BDKRB1, BMP4, BUB1, BUB1B, TSPO, CALM3, CAV3, CCNB1, CDC20, CDC27, CDK5, CDKN1A, CDKN2D, CENPF, CHAD, CRY2, CRYBA1, DCN, DLG2, DLG3, DNMT1, DNMT3B, DUSP1, DUSP5, DUSP7, DUSP9, FBLN1, FYN, GNAQ, GP1BA, RAPGEF1, HHEX, HMGCR, HPN, DNAJB2, HSPB1, IGF1, IGF1R, IGFBP3, ILK, JARID2, JUN, LIMK1, MAD2L1, SMAD3, SMAD6, SMAD7, MEN1, NTRK3, P2RX7, PCP4, PDPK1, PHB, PPP2R1A, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, DNAJC3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTPN2, PTPN6, PTPRJ, PTPRR, RB1, RPS3, RPS27A, SET, SMPD1, SNCA, SNTA1, SORL1, SOX4, SPINK1, TRIM21, TAF7, TARBP2, NR2F2, TP73, TTK, UBB, UBE2D1, USP4, WNT1, ZNF207, AKAP1, CUL3, OGT, CDC23, CDC16, SOCS3, RGN, LATS1, ZW10, BUB3, ITGB1BP1, SOCS6, KLF4, TRIP12, SLIT2, SLC9A3R1, ATG5, PSMF1, TMEM59, BAG5, BAG4, GMFG, PPM1F, KDM4A, RASSF2, SFI1, RANBP9, CTDSP2, FRY, FARP1, PSME3, PSMD14, CTDSPL, SPRY1 |
1644 | GO:0007605 | 0.01 | 1.76 | 23.71 | 34 | 81 | sensory perception of sound | ATP2B2, ALDH7A1, CDKN2D, CHRNB2, COL1A1, COL2A1, COL4A3, COL11A1, COCH, DIAPH1, DNM1, EYA4, GABRA5, GABRB2, GJB2, GPX1, HEXB, HPN, ICAM1, KCNQ1, KIT, PAX3, SERPINB6, RPL38, SCN8A, SLC12A2, TBL1X, ZNF354A, CLRN1, WFS1, FZD4, SLC9A3R1, FAM65B, WDR1 |
1645 | GO:0009056 | 0.00 | 1.76 | 33.96 | 49 | 122 | catabolic process | ADAM10, ANXA5, CAPS, COL1A1, COL2A1, COL4A3, COL4A5, COL4A6, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, COL10A1, COL11A1, COL15A1, COL19A1, COX8A, FANCF, GABRA5, ITGB1, KCNK3, P2RX5, PEPD, PRKG1, SLCO1A2, SLC22A3, SNRPD1, SNRPF, STAT2, ADAM17, NR2C2, COL14A1, ZNF189, CHAF1B, ADAM15, CES2, PTER, CHST3, ADAMTS3, ADAMTS2, NUP93, ATG13, RIMS3, PHYHIP, TOMM20, MFN2, FGFBP1 |
1646 | GO:0032231 | 0.04 | 1.76 | 14.63 | 21 | 50 | regulation of actin filament bundle assembly | ARHGAP6, BBS4, CTGF, S1PR1, LPAR1, ID1, LIMK1, SMAD3, PFN2, PRKCQ, RAC1, SDC4, SLC9A1, TSC1, VIL1, WNT11, ARHGEF5, ITGB1BP1, BAG4, PPM1F, WASF2 |
1647 | GO:0065009 | 0.00 | 1.75 | 131.51 | 187 | 482 | regulation of molecular function | ACACB, ADAR, NR0B1, ANXA1, ANXA4, ANXA5, BIRC3, XIAP, BIRC5, AQP1, ARL2, BBS4, BICD1, BST2, BUB1, BUB1B, C3, CCNE1, CD44, CDC25A, CDC25C, CDK2, CDK4, CDKN2D, CENPF, CHAD, CKS1B, CMKLR1, CNN3, CNR1, COL6A3, CRY2, CRYAB, CSNK2A1, CST1, CST6, DCN, DLG2, DLG3, DPEP1, RCAN1, DUSP1, ECM1, EDNRB, EIF4A2, SERPINB1, ENSA, EPHA3, EPHB3, IFI6, GALR1, GPC3, GNAI3, GP1BA, GPI, GPX1, HHEX, HMGCR, FOXA2, HP, HPN, HRG, HSPB1, IGF1R, IL13, ITIH1, ITIH2, ITIH4, KNG1, IPO5, LIMK1, MAD2L1, SMAD7, MGMT, OAS1, OAS3, OAZ1, OAZ2, SERPINE1, PALM, PAX2, SERPINA5, PCP4, SERPINF1, SERPINA4, SERPINB5, SERPINB6, SERPINB9, SERPINI1, SERPINB13, SERPINI2, PPP1R3C, PPP1R7, PPP1R8, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PPT1, PRKAB2, PRKG1, DNAJC3, PROS1, PRPSAP1, PTCH1, PTGIS, PTN, PTPN2, PTPN6, PTPRJ, PTPRN2, PZP, RAC2, RAG1, RANBP2, RAP2B, RB1, RBL2, RENBP, RNF2, RPS6KA1, RPS6KA3, SORT1, SERPINB4, SET, SFRP5, SIAH2, SLAMF1, SMPD1, SNCB, SNRNP70, SPINK1, SPOCK1, TAF7, TARBP2, SERPINA7, DYNLT1, NR2F2, TNNC1, TNNI3, TPM2, HSP90B1, TSG101, TTK, TNFSF4, SCGB1A1, UVRAG, VIL1, WAS, ZNF207, SHOC2, FZD6, NR0B2, PIK3R3, IKBKAP, TP63, DYNLL1, SERPINB7, TNFSF14, DPM2, TAX1BP1, SOCS3, DIRAS3, USP14, LATS1, DGKI, ZW10, BUB3, SOCS6, SLIT2, RAB9A, CABP1, BAG5, BAG4, BAG3, APBA3, GABBR2, RUBCN, PHACTR2, KIAA0141, SFI1, NUAK1, HDAC6, FEM1B, FRY, RCAN2, SPRY1 |
1648 | GO:0006821 | 0.02 | 1.75 | 18.14 | 26 | 62 | chloride transport | TSPO, CLCA1, CLCN2, CLCN3, CLCN6, CLCN7, CLCNKA, CLCNKB, CLNS1A, GABRA4, GABRA5, GABRB2, GABRE, GABRG1, GABRR1, GABRR2, GLRA1, GLRB, P2RY4, P2RY6, FXYD3, PTAFR, SLC4A1, SLC12A1, SLC12A2, SLC12A6 |
1649 | GO:0010558 | 0.00 | 1.75 | 34.81 | 50 | 123 | negative regulation of macromolecule biosynthetic process | ACVRL1, ADAR, ANG, APBB1, ATF4, ATR, BMPR2, BRCA2, CDC6, CIRBP, CLTC, DAPK3, DDX3X, DUSP1, EIF4E, EIF4EBP2, EPRS, GAPDH, GHSR, GRB7, HNRNPC, IL10, INHA, EIF3E, IREB2, ITGAV, KCNK2, CAPRIN1, SMAD1, RAN, RAP1A, RBM4, UPF1, RPS3, S100A11, SFTPD, SRP9, TARBP2, TSC1, TTF1, SMC1A, PRKRA, EIF4EBP3, EIF2B3, SMC3, EIF2AK3, TMEM59, PUM1, EIF4A3, PRG4 |
1650 | GO:0051052 | 0.00 | 1.75 | 43.49 | 62 | 149 | regulation of DNA metabolic process | ANXA3, APAF1, APBB1, ATR, ATRX, BAX, BMP4, BRCA2, CD28, CD40, CDC6, CDK2, CEBPG, CHEK1, CSF2, DFFA, DNMT1, DNMT3A, ERCC4, HNRNPC, IFNG, IGF1, IGF1R, IL3, IL10, INS, JUN, KPNA1, KPNA2, KITLG, MGMT, PCNA, PPP2R1A, PPP4C, RAC1, RAD51, RBBP6, RPA2, RPS3, S100A11, SETMAR, SHC1, STAT6, TOP2A, TTF1, TNFSF4, UBE2V1, UNG, XRCC5, ZNF91, SMC1A, CUL4A, TNFSF13, RNF8, SMC3, TRIP12, IL27RA, BRE, PARP3, RAD50, TRIM28, ALYREF |
1651 | GO:0051260 | 0.00 | 1.74 | 45.65 | 65 | 156 | protein homooligomerization | ACACB, ACADS, ACAT1, ALAD, ANXA5, ANXA6, APAF1, ARG1, BAX, BIK, CAT, ENTPD2, CDA, CLU, CLDN3, CRYAB, CTH, DHPS, DPYSL3, GLRA1, GOLGA2, HPRT1, HSF4, TNFRSF9, IMPDH2, ITPR3, KCNA1, KCNA3, KCNA4, KCNA5, KCNC2, KCND2, KCND3, KCNJ2, KCNS1, KCNS2, KCNS3, P2RX1, P2RX3, P2RX4, PAM, PLN, PEX5, RAD51, RXRA, RXRG, SHMT1, SHMT2, SLC6A4, SLC34A1, SLC22A1, SOD2, SYT1, TAF10, TRAF2, CLPP, OGT, TP63, RIPK1, HRK, PEX11B, CLDN1, EIF2AK3, CEP57, BCL2L11 |
1652 | GO:0051234 | 0.00 | 1.74 | 396.65 | 535 | 1408 | establishment of localization | ABCA2, ABCA3, ABCB7, ABCA4, ACACB, ACTB, ACTN1, ADA, ADCY1, ADCY7, ADCYAP1R1, ADD1, ADD3, ADRBK1, AGTR1, ALB, ABCD1, BIN1, ANPEP, ANXA3, ANXA6, ANXA11, APOF, APOH, APP, APRT, AQP1, AQP5, AQP6, ARG1, ARL1, ARR3, ASGR1, ATF4, ATP1A1, ATP1A2, ATP1A3, ATP12A, FXYD2, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP4A, ATP4B, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATR, KIF1A, AVPR2, AXL, BCL2A1, BCR, BDKRB1, BGLAP, BICD1, BST2, C3, CA1, CA4, CA6, CACNA1B, CACNB2, CACNB4, CACNG1, SLC25A20, CALM3, CAMK2A, CASQ1, CASQ2, CBL, CD4, CD5, CD5L, CD6, CD9, SCARB1, CDK2, CDO1, CDX2, CEBPE, CHAT, AKR1C4, CHKA, CHRNB2, CHRNB4, CHUK, CLCA1, CLCN2, CLCN3, CLCN6, CLCN7, CLCNKA, CLCNKB, CLNS1A, CCR1, CNGA1, CNGA2, CNP, COMT, COX6A1, COX6B1, COX7A1, COX7B, COX7C, COX8A, COX15, CPT1B, CPT2, CRAT, CREB1, CRHBP, CRY2, CRYAB, CSF2, SLC25A10, CTGF, CTNS, CTSS, CXADR, CYB5A, CYBA, CYP27B1, CD55, DBI, ACE, DHODH, DIAPH1, DPP6, TSC22D3, EDNRA, EDNRB, CELSR2, EIF4E, EMP2, SLC29A1, EYA2, F2, F7, F10, FABP2, FABP7, PTK2B, FCER1A, FCGR2A, FCGRT, FCN2, FGF7, FTL, FYN, G6PC, GABRA4, GABRA5, GABRB2, GABRE, GABRG1, GABRR1, GABRR2, GAD1, GALR1, GAS1, GCGR, GDF9, GDNF, GFAP, B4GALT1, GHRHR, GIF, GJA3, GJA4, GJB1, GJB2, GPC3, GLRA1, GLRB, GM2A, GNAI3, GOLGB1, GOT2, GPM6A, XCR1, FFAR3, GRB2, GRIA4, GRID1, GRID2, GRIN2A, GUCA2B, HAS2, HBA1, HBA2, HBD, HBE1, HGF, HHEX, HIP1, HP, HPN, HPX, HRC, HRG, HTR2C, ICAM1, IGF2, IGF2R, IL13RA2, INHA, INPPL1, INSIG1, IREB2, ITGAV, KCNA1, KCNA3, KCNA4, KCND2, KCND3, KCNH2, KCNJ1, KCNJ2, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNQ1, KCNS1, KCNS2, KIF5A, KISS1, KIT, KNG1, LCAT, LIMK1, LIPC, LRPAP1, LTF, MAL, MFGE8, MYO1B, PPP1R12A, NTRK2, NTSR1, OLR1, ORM2, OSBP, OXTR, P2RX1, P2RX3, P2RX4, P2RX5, P2RY2, P2RY4, P2RY6, SERPINE1, SERPINA5, PCP4, PDE4B, ABCB1, PIK3C2A, FXYD3, PLN, PRKAA1, PRKAB2, PRKD1, PRL, PROC, PROS1, PRSS8, PSAP, PTAFR, PTEN, PTH, PTGS1, PTPN3, PTPN6, ABCD3, ABCD4, RAC1, RALA, RANBP1, RAP1GAP, RARA, RBM4, RBP1, RBP2, RCVRN, UPF1, RHAG, RHCE, RHD, RLBP1, RPS6KB1, RXRA, RYR1, S100A1, SORT1, S100A8, S100A9, SCN1A, SCN2A, SCN2B, SCN4B, SCN5A, SCN7A, SCN8A, SCNN1A, SCNN1B, SCNN1G, SCO1, CCL21, XCL1, SDC1, SDC4, SEC14L1, SELE, SELP, SET, SRSF1, SRSF5, SRSF7, SFTPD, SGK1, SLAMF1, SLC1A6, SLC2A3, SLC2A4, SLC2A5, SLC4A1, SLC5A2, SLC6A2, SLC6A4, SLC6A6, SLC6A7, SLC6A8, SLC6A13, SLC7A1, SLC7A4, SLC8A1, SLC8A3, SLC9A2, SLC9A3, SLC10A1, SLC12A2, SLC13A1, SLC34A1, SLC20A1, SLC20A2, SLCO2A1, SLCO1A2, SLC22A1, SLC22A3, SLC22A2, SLC22A5, SIGLEC1, SNTA1, SOX11, SPARC, SPG7, SPINK1, SPTA1, SPTB, STAT5B, STC1, SYP, SYPL1, SYT4, TAF7, SERPINA7, DYNLT3, ICAM5, TNFAIP2, TNNC1, TP73, TPD52, TPT1, TRPC1, TRPC3, TRPC4, TRPC5, TSC1, TUBA4A, TULP1, TYRO3, UBE3A, SUMO1, UCP1, UPK3A, UQCRC1, UQCRFS1, UQCRH, UVRAG, VAV1, VCL, VDAC1, VDAC2, VDR, VEGFA, VEGFB, TRPV1, VTN, WAS, LAT2, WFS1, WRN, ZFPL1, SLC30A1, SLC30A2, LRP8, LAPTM5, TUBA1A, KCNAB1, TUSC3, SLC25A16, FGF23, ANP32A, SLC7A5, SLC14A2, SYN3, SLC10A3, ARID1A, DYSF, PICALM, FZD4, EEA1, LTBP4, PIK3R3, KCNAB2, CYP4F2, FCN3, KHSRP, SLC25A12, PEA15, SRSF9, ABCC3, RIPK1, INPP4B, NRP1, CD84, PROZ, ARHGEF7, SLC5A6, EIF2S2, SLC25A14, PSTPIP1, SLC13A2, CLDN10, USP6, RGN, SLC16A6, SLC16A5, SYNGR3, SLC6A5, DGKI, KCNAB3, DCLK1, VAPB, VAPA, PDLIM7, CYTH2, TRIP10, TRIP4, CD163, NRXN3, SLC22A8, COX5A, NRXN2, LIPG, SLC22A14, KCNK6, GSTO1, AKAP7, SLC4A7, MPDU1, RIN1, SNCAIP, CLINT1, PUM1, RUBCN, USP6NL, SEC14L5, EIF4A3, PIEZO1, DHX38, CKAP5, SCRN1, RGP1, DNAJC6, GAB2, ZC3H11A, OSBPL2, SMG7, SV2B, SGSM2, ATP2C2, RBM8A, OXSR1, WDR1, GOLGA5, SLC12A6, HCN4, HMGXB4, ABCC5, ABCB6, ABCC9, ABCF2, ATP9A, COL4A3BP, KCNK7, ARPC5, ARPC1B, ARPC2, SGK2, ACTR1A, AKAP9, G3BP1, WASF2, SLC25A13, SLC25A15, ALYREF, PRG4, SLC35B1, KCNMB2, RABEPK, ABCC4 |
1653 | GO:0000904 | 0.04 | 1.74 | 14.59 | 21 | 52 | cell morphogenesis involved in differentiation | ACTN1, BMP4, CASP9, CLDN3, EP300, ERG, HGF, RBPJ, IHH, PTPN6, S100A4, SOX9, ST14, STC1, TAL1, WNT11, IFT88, EOMES, ADAM15, LATS1, TRIM28 |
1654 | GO:0051668 | 0.03 | 1.74 | 16.10 | 23 | 55 | localization within membrane | ARCN1, ARF1, CD59, COPA, COPB1, CSNK1D, GOLGA2, GRIA1, INSIG1, MAL, PPP6C, PRKCI, RAB1A, RAC1, RALA, TRAPPC2, CUL3, USO1, VAPB, VAPA, COPB2, SEC22B, GOSR2 |
1655 | GO:0022603 | 0.00 | 1.74 | 39.23 | 56 | 136 | regulation of anatomical structure morphogenesis | ACVRL1, ADA, ANGPT2, ANXA3, APOH, KLK3, AQP1, ADGRB2, C3, KRIT1, CD36, CDX2, CCR3, COL4A3, CTSH, CX3CR1, DCN, DHODH, ECM1, EPHA2, EMP2, ETS1, F3, FLT1, FLT3LG, GATA4, GATA6, GTF2I, HHEX, HSPB1, IL1A, IL1RN, ITGA5, FOXO4, OPA1, OTX2, SERPINE1, PAX3, SERPINF1, PRKCB, PRKD1, PROX1, PTGIS, PTGS2, RAP1A, RRAS, CX3CL1, SFRP5, SP100, VEGFB, TNFSF14, TNFSF13, TNFSF12, KLF4, GDF15, PDCD6 |
1656 | GO:0010628 | 0.00 | 1.74 | 42.59 | 61 | 153 | positive regulation of gene expression | ACTA2, ACTG2, ADAR, AVPR2, PRDM1, C3, CCNB1, CD3E, CD44, CDK4, CDK6, CIRBP, CRH, CRP, CSF2, CTGF, CTSH, DAZ1, DNMT1, DNMT3B, EIF5A, ELAVL1, F12, PTK2B, FBLN1, FGF8, FGF9, FOXD1, HMX2, HPN, ID1, IL18, ITGA2, KLKB1, NTRK2, NTRK3, P2RX7, SERPINB9, PRKAA1, PRKAG1, DNAJC3, PTAFR, RAB27A, RPS6KA2, RPS6KB1, RPS6KB2, TRA2B, SLC6A4, SNRNP70, SRPK2, SSRP1, TARBP2, CNTN2, CLEC3B, KDM6A, VIM, NR0B2, CTDP1, PPM1F, RIMS2, EIF4A3 |
1657 | GO:0009119 | 0.00 | 1.74 | 53.56 | 76 | 183 | ribonucleoside metabolic process | ACACB, ACPP, ADA, ADSS, AHCY, AK1, AK2, ALDOC, AMPD2, APRT, ARNT, ATP1A2, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V0A1, BAD, BPGM, TSPO, CDA, COX8A, COX15, CTNS, DHODH, DLD, DLG2, DLG3, DNMT1, DNMT3A, DNMT3B, ENO2, GAPDH, GNAI3, GPI, GUK1, HK2, HMGCR, HPRT1, IGF1, IMPDH1, IMPDH2, INS, LDHC, OGDH, P2RX7, PFKFB4, PGAM1, PGK2, PPP2R5D, PRKAA1, PRKAG1, PRPS2, PTGDR, SDHC, SNCA, STAT3, SULT1E1, SULT1A3, SULT1C2, SULT2B1, TAZ, UPP1, UQCRC1, UQCRC2, UQCRH, OGT, PAPSS1, COX5A, ENTPD4, SLC25A13 |
1658 | GO:0030308 | 0.01 | 1.74 | 28.10 | 40 | 96 | negative regulation of cell growth | ACVR1B, ACVRL1, AGTR2, APBB1, APBB2, ARHGAP4, BDKRB1, BMPR2, BST2, CAV3, CDA, CDK5, CDKN1A, CDKN2D, CRYAB, CYP27B1, DCC, DDX3X, GDF9, HRG, ING1, SMAD3, PHB, PPP2R1A, PPT1, PTPRJ, RNF6, SEMA3F, SIPA1, SMARCA2, SMARCA4, TNR, WNT11, SEMA3B, ADAM15, NRP1, CTDP1, SLIT2, AATK, SEMA3E |
1659 | GO:0045834 | 0.02 | 1.73 | 21.07 | 30 | 72 | positive regulation of lipid metabolic process | AGTR1, ANXA1, APOH, SCARB1, CREB1, EPHA8, PTK2B, FGFR3, FGR, FLT1, FLT3, GHSR, GPLD1, HTR2C, IFNG, INS, KIT, PRKAA1, PRKCE, PTGS2, PTK2, RAC1, CCL21, SREBF1, TNFRSF1A, NR1H2, ZP3, NSMAF, RGN, NR1D1 |
1660 | GO:0098661 | 0.03 | 1.73 | 17.56 | 25 | 60 | inorganic anion transmembrane transport | CLCA1, CLCN2, CLCN3, CLCN7, CLCNKA, CLCNKB, GABRA4, GABRA5, GABRB2, GABRE, GABRG1, GABRR1, GABRR2, GLRA1, GLRB, FXYD3, PTAFR, SLC4A1, SLC12A1, SLC12A2, SLC13A1, SLC34A1, SLC20A1, SLC20A2, SLC12A6 |
1661 | GO:0044248 | 0.00 | 1.73 | 61.22 | 87 | 216 | cellular catabolic process | ABAT, ACAT1, ADA, ADH5, AHCY, ANPEP, ARG1, ASL, ASPA, ALDH7A1, AUH, BCAT2, BCKDHA, BHMT, BLVRA, CAPN1, CAT, ENTPD2, CDA, CDK5, CDO1, TPP1, CNP, COMT, VCAN, CSPG4, SLC25A10, CTH, CYP1A2, CYP2A6, CYP3A4, CYP27B1, DAO, DBH, DBT, ACE, DLD, DPEP1, TYMP, ENPEP, ESD, GAD1, GALNS, GLDC, GLUD1, GOT2, GPI, GPT, GSTZ1, HBA1, HBA2, HEXA, HNMT, HPD, HPRT1, IDS, IDUA, IDO1, LTA4H, NUDT1, NTHL1, OAT, OMD, OGDH, OXCT1, PRDX1, PAH, PDE4B, PDE8A, QDPR, RENBP, SHMT1, SUOX, TAT, PRDX2, UNG, UPP1, XPNPEP1, FGF23, DDO, PDE5A, ALDH4A1, MBD4, KYNU, GSTO1, ENTPD4, XYLB |
1662 | GO:0002252 | 0.00 | 1.73 | 31.58 | 45 | 110 | immune effector process | ABL1, ACTB, ADA, BCL3, CD3G, CEBPG, CLU, CR2, CRP, CTSG, CTSH, CX3CR1, DBH, ACE, EMP2, PTK2B, FCGR2A, FCN2, GATA3, GRB2, CFHR1, ITGAL, ITPR1, ITPR3, LIMK1, PRDX1, PRKCE, MAPK1, MAPK3, PTK2, SLAMF1, ADAM17, TSC1, TYROBP, KDM5D, EOMES, IL18R1, RNF8, EXO1, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, WASF2 |
1663 | GO:0030010 | 0.04 | 1.73 | 14.05 | 20 | 48 | establishment of cell polarity | KRIT1, CENPA, EPHB1, PTK2B, FLOT2, GATA3, LLGL2, MAP1B, NUMA1, PRKCI, PTK2, CCL21, FSCN1, DYNLT1, ARHGEF2, ZW10, SLC9A3R1, ARHGEF11, RNF41, SPRY1 |
1664 | GO:0010608 | 0.00 | 1.73 | 82.24 | 116 | 281 | posttranscriptional regulation of gene expression | ADAR, ANG, APP, ATF4, BCL3, ZFP36L2, CD28, CDK4, CIRBP, DAPK3, DAZ1, DDX1, DDX3X, DDX6, DKC1, EIF2B1, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4EBP2, EIF4G2, EIF5, EIF5A, ELAVL1, EPRS, PTK2B, GAPDH, GDNF, GRB7, HNRNPC, HSPB1, IGF1, EIF3E, IREB2, ITGA2, CAPRIN1, SMAD1, SMAD3, CNOT2, YBX1, PA2G4, EXOSC9, PPP1CA, MAPK1, MAPK3, DNAJC3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTAFR, PURA, RAN, RARA, RBM4, UPF1, RPL38, RPS3, RPS6KA1, RPS6KA3, RPS6KB1, RPS6KB2, RPS27A, RXRA, S100A9, SET, SOX4, SRP9, TARBP2, TNFRSF1B, TSC1, UBB, SCGB1A1, VIP, EIF4H, YWHAZ, NUP214, ANP32A, KHSRP, PRKRA, EIF4EBP3, EIF3F, EIF3G, EIF4G3, TNFSF13, EIF2B3, EIF2B2, EIF2AK3, PSMF1, EIF5B, PUM1, EIF4A3, RBM8A, TRAP1, PSME3, EIF1, PSMD14 |
1665 | GO:0048754 | 0.04 | 1.73 | 15.47 | 22 | 53 | branching morphogenesis of an epithelial tube | AGTR2, BMP4, CD44, CTSH, FOXD1, GDNF, B4GALT1, GPC3, HHEX, FOXA2, IGF1, ILK, KDR, PAX2, PPP1CA, PSPN, PTCH1, SALL1, SOX9, WNT1, SLIT2, SPRY1 |
1666 | GO:0007389 | 0.00 | 1.72 | 60.20 | 85 | 206 | pattern specification process | ACVR2B, ALX3, ASCL1, BBS4, BMI1, BMP4, BMPR1A, BMPR2, CDX2, CRKL, EFNB1, CELSR2, EGR2, EMX1, EMX2, EN1, EP300, ETS2, EVX1, FGF3, FOXD1, GATA4, KAT2A, GDNF, GPC3, HHEX, FOXA2, HOXC10, HOXC11, HOXD4, HOXD8, HOXD9, HOXD10, HOXD12, RBPJ, ISL1, SMAD1, SMAD3, SMAD6, MEOX2, NTF4, OTX1, OTX2, PAX2, PAX3, PCDH8, PCSK5, PRKACB, PSKH1, PTCH1, RFNG, RFX3, RFX4, RNF2, SEMA3F, TRA2B, STIL, SIM2, SIX3, SMARCD3, SNAI1, STC1, T, NR2F1, NR2F2, TULP3, KDM6A, WNT1, XRCC2, YY1, ZIC1, FZD5, IFT88, EOMES, RGS20, TP63, CHRD, DNAH11, KIF3B, HAND1, IFT140, ZEB2, FRAT1, ATP6AP2, SPRY1 |
1667 | GO:0007254 | 0.01 | 1.72 | 27.51 | 39 | 94 | JNK cascade | CRKL, CTGF, DUSP9, EPHA4, EPHB1, ERCC6, PTK2B, FCER1A, FLT4, IGF1R, IL1A, IRAK1, IRAK2, MEN1, MAP3K11, RAP2A, RPS3, RPS27A, CCL21, SLAMF1, SYK, TP73, TPD52L1, TRAF2, UBB, FZD5, ARHGEF5, FZD4, FZD7, FZD8, IKBKG, RIPK1, RIPK2, TRAF4, RASSF2, RB1CC1, ZEB2, SH2D3C, SH2D3A |
1668 | GO:0006816 | 0.01 | 1.72 | 22.51 | 32 | 78 | calcium ion transport | ANXA5, ANXA6, ATP2B1, ATP2B3, CACNA1A, CACNA1B, CACNB1, CACNB4, CACNG1, CAMK2G, CHRNB2, CLCA1, CTGF, CYP27B1, FYN, GJA4, GPM6A, GRIN2A, IGF1, ITGAV, KCNN4, P2RX1, PDE4B, PRKCB, RCVRN, TPT1, TRPC5, VDAC1, VDR, CD84, ATP2C2, RAMP3 |
1669 | GO:0051172 | 0.01 | 1.72 | 23.14 | 33 | 82 | negative regulation of nitrogen compound metabolic process | ADAR, ANG, ATF4, CIRBP, CLU, CLTC, COMT, DAPK3, DDX3X, EIF4E, EIF4EBP2, EPRS, GAPDH, GRB7, IL10, EIF3E, IREB2, CAPRIN1, SMAD1, PRKAA1, RAN, RBM4, UPF1, SORL1, SRP9, TARBP2, TSC1, PRKRA, EIF4EBP3, EIF2B3, EIF2AK3, PUM1, EIF4A3 |
1670 | GO:0006518 | 0.03 | 1.72 | 16.17 | 23 | 56 | peptide metabolic process | AEBP1, ANPEP, CLU, TPP1, CTNS, CTSG, CTSH, ACE, DPEP1, ENPEP, FSHB, GLO1, GPX1, GSTZ1, IDH1, LTA4H, PAM, SORL1, XPNPEP1, PICALM, PCSK7, GSTO1, ATP6AP2 |
1671 | GO:0031032 | 0.01 | 1.72 | 24.00 | 34 | 82 | actomyosin structure organization | ARHGAP6, BBS4, CASQ1, CASQ2, CAV3, CNN1, CNN2, CNN3, CTGF, S1PR1, LPAR1, PTK2B, ITGB1, ITGB5, LIMK1, SMAD3, PFN2, PRKAR1A, PRKCQ, PROX1, RAC1, SDC4, SLC9A1, SRF, TSC1, WNT11, ARHGEF5, CUL3, ITGB1BP1, BAG4, CDC42BPB, PPM1F, WDR1, WASF2 |
1672 | GO:0032880 | 0.00 | 1.72 | 155.99 | 217 | 533 | regulation of protein localization | ABAT, ABL1, ABL2, ACTL6A, ADAM8, AGTR2, ALOX15B, ANG, ANGPT1, SLC25A4, ANXA1, ANXA4, ANXA5, APBB1, ARF1, ARHGDIG, ARL2, ARNTL, BAD, BARD1, BCL2L1, BCL3, BLK, BMP4, BMPR1A, BNIP3L, CACNA1A, CASP5, CASP8, CAV3, CCNB1, CD14, CD36, CD40, CD58, CDH1, CDK5, CDKN1A, CHRM1, CHRM3, AP2M1, CLTC, CNR1, CRH, CRP, CSF1R, CSNK2A2, CTSK, DKC1, DRD3, EDA, EFNA5, CELSR2, EPHA2, EMD, ENSA, EPHA5, F2R, FBLN1, FGA, FGR, FYN, GATA3, GCG, KAT2A, GDI1, GHSR, GLUD1, GNAQ, GNAS, GPLD1, GPM6B, GPR26, FFAR1, HCLS1, NRG1, HMGCR, FOXA2, HNMT, DNAJB2, IFNA2, IFNG, IGF1, IL1A, IL10, IL12B, IL13, TNFRSF9, IL18, INS, ISL1, ITGB1, ITPR1, ITPR3, JUP, KCNA5, KCNC2, KCNJ11, KCNN4, KCNS3, KPNA1, IPO5, LLGL2, SMAD3, RAB8A, TONSL, OAZ1, OAZ2, OXCT1, P2RX7, PAEP, PRDX1, PAM, PCM1, PDPK1, PPID, PPM1B, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRKCI, PRKCQ, PSMB7, PSMD8, PSMD9, PTCH1, PTGS2, PTN, PTPN14, RAC2, RANGAP1, RAP1A, RB1, REST, RFX3, RNASE2, RPL28, CX3CL1, SFRP5, SLC2A2, SLC9A1, SNAP25, SORL1, SOX4, SP100, SREBF1, SYK, SYT5, TRAF2, TRH, TRIP6, TRPM2, TSG101, TNFSF4, UBE2L3, SUMO1, NR1H2, VEGFA, VIL1, VIP, YWHAH, YWHAZ, ZIC1, ZBTB17, FZD5, ARHGEF5, AKAP1, PICALM, BAP1, FZD7, NR0B2, DYRK2, OGT, KCNAB2, RGS20, RUVBL1, NUMB, DYNLL1, VAMP8, TNFSF14, IL18R1, IQGAP1, CDKL2, SYT7, IL1RL1, RAB11B, ITGB1BP1, HMGN3, RAB9A, SLC9A3R1, NRXN1, EIF2AK3, AKAP6, ATG5, CABP1, LITAF, TMEM59, BAG4, NR1D1, CLOCK, ATG13, KIAA0586, SPCS2, C2CD5, FAM20B, NR1H4, HDAC6, BCL2L11, SAE1, TRIM28, NUTF2, STX6, RAMP3 |
1673 | GO:0031325 | 0.04 | 1.72 | 14.59 | 21 | 55 | positive regulation of cellular metabolic process | ABAT, ACACB, ANXA1, ASIP, TNFRSF8, SCARB1, CD63, COMT, FGR, GHSR, HPRT1, HSPB1, RAB1A, SELE, ITSN1, NR2F1, ZNF16, NSMAF, PICK1, HDAC6, RAMP3 |
1674 | GO:0045892 | 0.00 | 1.72 | 55.20 | 78 | 193 | negative regulation of transcription, DNA-templated | BIRC5, ARNTL, BCL3, RUNX2, CDK5, CENPF, CREB1, ELF3, ELK3, FOXD1, HIST1H2AD, H3F3B, NRG1, HMGA1, IFNA2, IRF1, PA2G4, PAX2, PAX9, CHMP1A, PHF2, PSMC5, PURA, RFX3, SET, SIX3, SMARCE1, SOX5, SOX9, SOX10, TBP, TSG101, WNT11, XRCC5, ZNF24, ZNF91, ZNF154, ZNF224, ZP3, KDM5C, HIST1H4I, CDC45, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, ZNF282, HAT1, HESX1, HIST1H3F, HIST1H2AG, TAF1B, TAF1A, UBA3, CBFA2T2, RPS6KA5, CIR1, CLOCK, PPM1F, KDM4A, NR1I3, NR1D2, ZBTB33, HDAC6, ZNF263, YAF2, ZNF256, RAMP3 |
1675 | GO:0045786 | 0.05 | 1.72 | 14.08 | 20 | 49 | negative regulation of cell cycle | ALOX15B, CCNF, ETS1, GATA3, HHEX, NR4A1, HPGD, MEN1, NUBP1, PRKACB, PRKAR1A, PTGS2, RPS6KA2, SIPA1, SOX11, NR2F2, ZBTB17, LATS1, SMC3, AURKB |
1676 | GO:0006357 | 0.00 | 1.72 | 33.06 | 47 | 118 | regulation of transcription from RNA polymerase II promoter | ABCA2, ACTL6A, ANXA4, KLF9, CHD2, CHEK1, ECM1, ERG, GLO1, GSC2, HMGN1, HNF4G, MAZ, PAM, PRKAR1A, PRKCB, PTAFR, PURA, RBL2, RFX1, SMARCD3, SMARCE1, SOD2, SP2, SPIB, STAT2, TARBP1, ZNF354A, UBE2D2, UCP1, ZNF76, ZNF131, ZNF143, VEZF1, CUL2, SMARCA5, IKBKAP, BLZF1, RUVBL1, KLF7, CREG1, CTDP1, LITAF, CIR1, RNF14, ZNF518A, RBX1 |
1677 | GO:0006839 | 0.00 | 1.71 | 46.24 | 65 | 158 | mitochondrial transport | ACACB, ACTL6A, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, BAD, BAX, BCL2L1, BNIP3L, TSPO, SLC25A20, CAMK2A, CASP8, CNP, CPT1B, CPT2, CSNK2A2, SLC25A10, CTSK, EYA2, KAT2A, GFER, GPR26, NRG1, HK2, HNMT, HSPA4, HSPA9, PRKAB2, PSMB7, PSMD8, RAC2, RNASE2, RPL28, SLC8A3, SLC9A1, SREBF1, STAT3, UBE2L3, UCP1, VDAC1, YWHAH, YWHAZ, ZBTB17, FZD5, BAP1, SLC25A12, RUVBL1, DYNLL1, CDKL2, SLC25A14, BAG4, ATG13, TOMM20, FAM20B, MFN2, BCL2L11, SAE1, SLC25A13, SLC25A15 |
1678 | GO:0008202 | 0.00 | 1.70 | 39.11 | 55 | 134 | steroid metabolic process | ABCA1, AGTR1, NR0B1, ALB, APOF, APLP2, APP, ATP1A1, TSPO, CAT, COMT, CRH, CYP2A6, CYP8B1, CYP11B1, DHCR7, CYB5R3, FDFT1, FDPS, FSHB, NR5A2, G6PC, HMGCR, HMGCS2, FOXA2, HSD11B1, IFNG, INSIG1, LCAT, LIPA, LIPC, LIPE, PRKAA1, PROX1, REST, RXRA, SLC10A1, SLCO1A2, SNAI1, SORL1, SQLE, SREBF1, STAT5B, SULT1E1, SULT1A3, SULT2B1, TNFSF4, VDR, CNBP, NR0B2, ABCC3, GGPS1, NR1D1, NR1H4, DHRS2 |
1679 | GO:0002449 | 0.02 | 1.70 | 21.29 | 30 | 73 | lymphocyte mediated immunity | BCL3, BTK, C7, CD8A, CD74, CEBPG, CLC, CLU, CR1, CR2, CTSH, CD55, EMP2, GATA3, ICAM1, IFNA2, IGF2, IL10, IL13RA2, PRDX1, SERPINB9, PTPN6, RAB27A, SERPINB4, WAS, KDM5D, STX11, RNF8, EXO1, IL27RA |
1680 | GO:0051716 | 0.00 | 1.70 | 733.38 | 924 | 2710 | cellular response to stimulus | ABAT, ABCA4, ABL2, ACPP, ACTB, ACTN4, ACVR1B, ACVR2B, ACVRL1, ACY1, ADA, ADAM10, ADAR, ADCY1, ADCY7, ADCYAP1R1, ADH5, ADRA1B, ADRBK1, AP2B1, AGTR1, AGTR2, APLNR, NR0B1, AHCY, AHR, ALAD, ALDH1B1, ALK, ALOX15B, ANGPT1, ANGPT2, ANXA4, ANXA6, APBB2, BIRC3, BIRC5, APLP2, APP, APRT, KLK3, ARAF, TRIM23, ARF1, ARF4, ARF5, RND3, ARHGAP4, ARHGAP5, ARHGAP6, ARHGDIB, ARHGDIG, ARL1, ARL2, ARR3, ASIP, ATP1A3, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6AP1, AVPR1B, AVPR2, ADGRB2, BBS4, BCL9, TNFRSF17, OPN1SW, BCR, BDKRB1, BICD1, BIK, BLK, BMP1, BMP3, BMP8B, BMX, DST, BSG, BST2, KLF9, BTK, BUB1, BUB1B, C3, CAPN5, DAGLA, CACNA1A, CACNB4, CAMLG, CASP10, CASQ1, CASQ2, CAT, RUNX2, CBL, CBLB, KRIT1, CCNC, CCNT2, CD3D, CD3E, CD3G, CD4, CD5, CD7, CD8A, CD9, CD28, TNFSF8, CD37, CD58, CD59, CD63, CD69, CD70, CD72, ADGRE5, CD151, CDA, CDC6, CDC20, CDC25C, CDH1, CDH6, CDK4, CDK5, CDK8, CENPA, CENPE, CENPF, CHAD, AKR1C4, CHKA, CHN1, CHN2, CHRM1, CHRM3, CHRNB2, CHRNB4, AP2M1, AP2S1, CLCN6, CLPS, CCR1, CCR3, CCR8, CMKLR1, CNR1, COL2A1, COL4A3, COL6A1, COL15A1, CLDN3, CPS1, CR1, CR2, CRH, CRYBA1, CSF1R, CSF2RB, CSH1, CSNK1G3, CSNK2A1, CSPG4, CTF1, CTNND1, CTNND2, CTSH, CTSS, CXADR, CYP1A2, CYP2A6, CYP2A13, CYP2F1, CYP3A4, CYP8B1, CYP11B1, DGKB, DAPK3, BRINP1, DBH, DCC, DIAPH1, DIAPH2, DLX5, DMBT1, DNM1, DNMT1, DOK1, DPYSL3, DRD3, DRD5, RCAN1, DTNA, DTX1, DUSP1, DUSP5, E2F5, ECM1, EDA, S1PR1, LPAR1, EFNA1, EFNA3, EFNA4, EFNA5, EFNB1, EFNB2, CELSR2, EGR2, EGR3, EIF2B1, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4EBP2, EIF4G2, ELF1, ELK3, EMD, EMP2, ADGRE1, EPHA3, EPHA5, EPHA8, EPHB2, EPHB3, EPRS, EPS15, ERG, ESD, ESRRG, ETV2, ETV3, EXT2, F2R, F2RL2, F7, F10, FBLN1, FBN1, EFEMP1, FCER2, FCGR2A, FCGR2B, FCGRT, GPC4, FGA, FGD1, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGF11, FGFR3, GPC5, FGR, FOXD1, FLT1, FLT3, FLT3LG, FMO3, FPR1, FPR2, FPR3, FSHB, CENPI, FSHR, NR5A2, ACKR1, FYB, FYN, FZD2, IFI6, GABRA4, GABRB2, GABRE, GABRG1, GABRR1, GABRR2, GALR1, GAPDH, GAS1, GATA4, GCG, GCGR, OPN1MW, GDF9, GDI1, GDI2, GDNF, GEM, GFRA1, B4GALT1, GH2, GHRHR, GHSR, GPC3, GLRA1, GLRB, GMDS, GNA15, GNAI1, GNAI3, GNAQ, GNAS, GNAT2, GNB2, GNG3, GNG10, GNGT2, GNRH2, GNRHR, GP1BA, GPC1, GPR1, GPR3, GPR4, XCR1, GPR15, GPR17, GPR19, LPAR4, GPR25, GPR26, FFAR1, FFAR3, GRB7, RAPGEF1, GRIA1, GRIA4, GRID1, GRID2, GRIN2A, CXCL2, CXCL3, GRPR, GSS, GSTZ1, GTF2I, GUCY2C, H3F3B, HAS1, HCLS1, NRG1, HHEX, HIP1, HIVEP2, HMBS, NR4A1, HNF4G, ONECUT1, HPGD, HPX, HRH1, HRC, HRG, HSPA9, HTR2C, IAPP, ICAM2, ID1, SP110, IFIT1, IFIT3, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNGR1, IFNW1, IGF2R, IGFBP3, IGFBP6, IHH, IL1R1, IL1RAP, IL1RN, IL2RA, IL2RB, IL2RG, IL3, IL10RA, IL11RA, IL12RB2, IL15RA, TNFRSF9, ILK, IMPDH2, INCENP, INHA, INPP1, IRF5, ISG20, ITGA1, ITGA4, ITGA5, ITGA7, ITGA9, ITGAD, ITGAE, ITGAL, ITGAM, ITGAV, ITGB5, ITPR3, JUNB, JUND, JUP, CD82, KCNA1, KCNA5, KCND3, KCNH2, KCNJ1, KCNJ11, KCNN4, KCNQ1, KIF5A, KISS1, KIT, KLK2, KLRC3, KPNA1, KPNA3, KPNA4, IPO5, KRT13, LIMK1, LIPC, LLGL2, LRPAP1, LSP1, LTBP2, MAD2L1, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAL, MARK3, RAB8A, SCGB2A1, MGAT3, KITLG, CIITA, PPP1R12A, PPP1R12B, CNOT2, YBX1, NTF4, NTRK2, DDR2, NTSR1, OAS1, OAS3, OCRL, OMP, OPHN1, OR1F1, OR2C1, OTX2, OXCT1, OXTR, P2RX1, P2RX3, P2RX4, P2RY4, P2RY6, P2RY11, PAX9, PCP4, PCSK5, PDE8A, PDPK1, PDYN, SERPINF1, PF4V1, PGR, PHB, SERPINB9, PIK3C2A, PIK3C2B, PI4KA, PLN, PPM1B, PPP2R1A, PPP2R1B, PRCP, PRKAB2, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCB, PRKCI, PRKCSH, PRL, PTCH1, PTGDR, PTGER1, PTGER2, PTH, PTGS1, PTH2R, PTK2, PTPN6, PTPRA, PTPRE, PTPRJ, PTPRN, PTPRN2, PTPRR, QDPR, RAB1A, RAB3A, RAB3B, RAB4A, RAB5A, RAB5B, RAB6A, RAB27A, RABIF, RAC2, RAC3, RAF1, RALA, RAN, RANBP1, RANGAP1, RAP1A, RAP1GAP, RAP2B, RARB, RASA2, RB1, RBP1, RBP2, OPN1LW, PRPH2, DPF2, RET, RFNG, RFX4, RGR, RGS1, RGS10, RGS12, RGS13, RHEB, RIT1, RLBP1, RNF6, RPL3, RPS6, RPS6KB1, RPS6KB2, RPS19, RPS27, RRAS, CLIP1, RSU1, RXRG, RYK, RYR1, RYR2, S100A1, SORT1, S100A4, S100A7, S100A8, S100A9, S100A11, S100A12, S100A13, SAA4, SALL1, TSPAN31, ATXN7, SCN5A, SCTR, CCL22, CCL25, CXCL6, CXCL5, XCL1, CX3CL1, SDC1, SDC4, SEC14L1, SELE, SELP, SELPLG, SEMA3F, SFRP5, SRSF5, SFTPD, SH3BGR, SH3BGRL, SH3BP2, ITSN1, SHB, SHMT1, SIAH2, STIL, SIX3, SLA, SLC2A5, SLC6A4, SLC34A1, SLC20A1, SMARCA4, SMARCC1, SMPD1, SIGLEC1, SORL1, SOS2, SOX5, SOX10, SOX11, SP1, SPARC, SPINK1, SPOCK1, SPTA1, SPTB, SRPK2, TRIM21, STAT3, STAT4, STAT5B, SULT1E1, STRN, STYX, SULT1C2, SULT2B1, XCL2, SYP, SYT1, T, TACR2, ADAM17, TACR3, TAF7, TARBP2, CNTN2, TBL1X, DYNLT1, NR2F1, NR2F2, NR2E1, TSPAN7, CLEC3B, TPMT, NR2C1, TRAF1, TRH, TRHR, TRIO, TRIP6, TRPC3, TRPS1, TSG101, TTK, TUFT1, TULP3, TYK2, TYRO3, TYROBP, UBE2L3, UBE3A, UPK1B, SCGB1A1, NR1H2, UROS, KDM6A, VAV1, VDAC2, VEGFB, VIL1, VIM, VIP, VIPR2, TRPV1, VTN, WAS, LAT2, WNT11, YWHAH, YWHAZ, ZIC1, ZNF16, ZNF35, ZNF217, ZP3, LRP8, IL1R2, SCG2, SEMA3B, FZD3, SHOC2, ANP32A, RND2, AKAP1, MADCAM1, NRIP1, CLTCL1, USP9X, USP9Y, ARID1A, FZD6, FZD9, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, OR1A1, OR1D5, OR1G1, OR3A3, SPARCL1, BCAR3, LTBP4, NR0B2, NSMAF, CUL3, SORBS2, SEMA7A, PIK3R3, CNTNAP1, IKBKAP, DGKE, CYP4F2, MADD, STK16, RGS20, UNC5C, SSNA1, OASL, PTCH2, CHRD, NUMB, PDE5A, DYNLL1, TNKS, EIF4G3, S1PR4, TRADD, CTNNAL1, HRK, TNFSF13, TNFSF12, TNFSF10, TNFSF9, ADAM15, TNFRSF18, DLK1, TNFRSF10D, PEX11B, PEX11A, IL1RL2, IL18R1, INPP4B, CES2, IQGAP1, NRP2, NRP1, WISP3, AKAP4, ARHGEF7, SGPL1, TAX1BP1, EIF2B2, BUD31, AP1M1, PHOX2B, AP3D1, HIST1H3F, RPS6KA4, ATP6V0E1, PGLYRP1, TNFSF18, CDKL2, SOCS3, TAAR5, UBA3, DOK2, PSTPIP1, PAPSS1, ANGPTL1, DIRAS3, UNC119, USP8, LATS1, ARHGEF1, DGKI, IL1RL1, RASSF9, ZW10, BUB3, REPS2, DCLK1, BMP15, XPR1, VAPA, STK17B, STK17A, CYTH2, ITGB1BP1, BCL7B, TAAR2, GPR55, GPR52, SOCS6, TRIP10, HMGN3, TRIP4, GLP2R, EFTUD2, SLIT2, KL, RAB9A, SLC9A3R1, NRXN3, ZFYVE9, NRXN1, NRXN2, GRAP2, ARHGAP29, GSTO1, AKAP7, IL27RA, AKAP6, ONECUT2, ADAMTS3, GDF15, NRG2, CXCL14, ATP6V1G1, BCAR1, GTPBP1, GABBR2, CDC42BPB, AKAP12, RNF14, RAB36, RIN1, AATK, GNA14, PPM1F, RALGPS1, ZNF516, SDC3, PHF14, RAPGEF2, PUM1, RIMS2, CEP57, ADAMTSL2, SEMA3E, KNTC1, USP34, IFT140, ARHGAP32, ZNF536, ZFYVE16, EIF4A3, SNX17, KIAA0586, CKAP5, SPOCK2, KIAA0141, ARHGEF11, GAB2, C2CD5, TRIL, RHOBTB1, DENND4B, MFN2, P2RY14, ARHGAP25, TNFSF15, NR1I3, NR1D2, NR2E3, ZBTB33, TANK, HCN4, FRAT1, HMGXB4, RANBP9, ABCC9, PTPRU, PDCD7, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, SGK2, ARL4A, ARFRP1, AKAP9, G3BP1, ABI2, RASA4, ATP6AP2, FARP1, WASF2, RNF41, RCAN2, RASGRP2, SPRY1, STAM2, RAMP3 |
1681 | GO:0043903 | 0.01 | 1.69 | 32.14 | 45 | 110 | regulation of symbiosis, encompassing mutualism through parasitism | ADAR, BAD, BST2, CD28, DDB1, DDX3X, DDX5, EP300, ERCC3, FBLN1, NR5A2, HPN, IFI16, IFIT1, IFNA2, ISG20, ITGAV, JUN, LTF, OAS1, OAS3, PPIB, PPID, PROX1, REST, SLPI, SMARCA4, SP1, SP100, SRPK2, TRIM21, SSRP1, STAU1, TARBP2, DYNLT1, TOP2A, TSG101, TRIM25, FCN3, OASL, CTDP1, VAPB, VAPA, BCL2L11, TRIM28 |
1682 | GO:1990138 | 0.01 | 1.69 | 24.29 | 34 | 83 | neuron projection extension | ABL1, ARHGAP4, BMPR2, CDK5, DNM2, EMX1, CTTN, GOLGA4, NRG1, ILK, ITGB1, LIMK1, MAP1B, NRCAM, NTRK3, RNF6, SEMA3F, SRF, SYT1, SYT4, TNR, VCL, VEGFA, SEMA3B, USP9X, SEMA7A, IQGAP1, NRP2, NRP1, DCLK1, SLIT2, AATK, RIMS2, SEMA3E |
1683 | GO:0030216 | 0.03 | 1.68 | 17.85 | 25 | 61 | keratinocyte differentiation | ALOX15B, ANXA1, CYP27B1, DNASE1L2, EPHA2, EVPL, RBPJ, IVL, KRT2, KRT16, REG3A, S100A7, SPRR2A, SPRR2D, SPRR2E, SPRR2G, SPRR3, ST14, TSG101, VDR, MADCAM1, TP63, AKR1C3, SCEL, LATS1 |
1684 | GO:1900180 | 0.01 | 1.68 | 32.19 | 45 | 110 | regulation of protein localization to nucleus | AGTR2, ANGPT1, BCL3, BMP4, BMPR1A, CD36, CDH1, CDKN1A, EDA, EMD, FYN, GNAQ, HCLS1, IGF1, IL10, IL12B, IL18, INS, JUP, KPNA1, IPO5, SMAD3, TONSL, PRDX1, PPM1B, PRKCQ, PTGS2, SFRP5, SLC9A1, TRIP6, ZIC1, AKAP1, FZD7, DYRK2, OGT, RGS20, TNFSF14, IL18R1, SLC9A3R1, EIF2AK3, AKAP6, CABP1, LITAF, TRIM28, NUTF2 |
1685 | GO:0002250 | 0.04 | 1.68 | 17.12 | 24 | 59 | adaptive immune response | TNFRSF17, CD1B, CD6, CD7, CD86, CTLA4, CTSS, ADGRE1, PTK2B, FGA, FYN, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, PRKCB, RAG1, SLAMF1, SYK, TSC1, LAT2, EOMES, CD84 |
1686 | GO:0010771 | 0.03 | 1.68 | 19.32 | 27 | 66 | negative regulation of cell morphogenesis involved in differentiation | ACTN4, ARHGAP4, CDK5, DCC, EFNA1, FBLN1, GDI1, FOXA2, HPN, ID1, SMAD7, PTEN, PTK2, RNF6, SALL1, SEMA3F, TNR, TTC3, YWHAH, SEMA3B, NRP1, ARHGEF1, ITGB1BP1, SLIT2, AATK, RAPGEF2, SEMA3E |
1687 | GO:0032874 | 0.03 | 1.68 | 19.32 | 27 | 66 | positive regulation of stress-activated MAPK cascade | CTGF, EPHA4, ERCC6, PTK2B, FCER1A, FLT4, HMGCR, PRMT1, IL1A, MAP3K11, RPS3, CCL21, SLAMF1, SYK, TPD52L1, TRAF2, VEGFA, FZD5, ARHGEF5, FZD4, FZD7, FZD8, RIPK1, RIPK2, TRAF4, RASSF2, ZEB2 |
1688 | GO:0030036 | 0.01 | 1.68 | 30.78 | 43 | 106 | actin cytoskeleton organization | ANXA1, AQP1, RND3, ARHGDIB, BCR, BST2, CDK5, CSF1R, CXADR, DAPK3, EFNA5, EPB41, EPB41L2, EPHA3, EPHA5, FGD1, FGF7, FLII, GPM6B, HRG, ILK, INSRR, KIT, LLGL2, ATXN3, NTRK3, OPHN1, PAM, PDPK1, PRKG1, RAC3, RALA, RAN, RAP2A, S100A9, SHC1, DYNLL1, PDLIM7, CYTH2, TRIP10, SLC9A3R1, SEMA3E, ARHGEF11 |
1689 | GO:0072175 | 0.02 | 1.68 | 20.76 | 29 | 71 | epithelial tube formation | APAF1, BBS4, CASP8, FZD2, KAT2A, GDNF, OPA1, PAX3, PRKACB, PTCH1, RALA, RARA, RET, SALL1, SDC4, STIL, SOX4, SOX9, SOX11, ST14, T, TSC1, TULP3, KDM6A, FZD3, ARID1A, FZD6, HAND1, ZEB2 |
1690 | GO:0006605 | 0.00 | 1.67 | 39.52 | 55 | 137 | protein targeting | ADAR, ARNTL, RERE, TSPO, CBLB, SCARB2, CSE1L, F2R, FGF9, FYB, GFER, GOLGA4, HSPA4, HSPA9, IFNG, JUN, KPNA2, KPNA3, KPNA4, LTBP2, NUP98, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, MAPK1, MAPK3, RAB6A, RAB27A, RAN, RANBP2, SIX3, SORL1, STAT3, SYK, TRPS1, YWHAZ, NUP214, AP3B1, AKR1C3, RASSF9, TRIP11, ZFYVE9, PICK1, AKAP12, NUP155, IPO13, NUP93, CEP57, ZFYVE16, TOMM20, MFN2, AP1M2 |
1691 | GO:0034440 | 0.05 | 1.67 | 15.80 | 22 | 54 | lipid oxidation | ACACB, ACADM, ACADS, ACOX1, ABCD1, CNR1, CPT1B, CPT2, CRAT, ECH1, EHHADH, ETFA, ETFDH, HADHA, HSD17B4, IVD, PDK4, PEX7, PEX13, PRKAA1, ABCD3, ACOX3 |
1692 | GO:1901799 | 0.05 | 1.67 | 15.80 | 22 | 54 | negative regulation of proteasomal protein catabolic process | BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DUSP1, MAD2L1, OPHN1, SMARCC1, TTK, UBE2D1, ZNF207, CDC23, CDC16, USP14, ZW10, BUB3, PSMF1, BAG5 |
1693 | GO:0034599 | 0.02 | 1.66 | 24.47 | 34 | 84 | cellular response to oxidative stress | ABL1, ANXA1, AQP1, ARG1, ARNT, ARNTL, BMP4, CDK2, DNM2, DPEP1, ETS1, ETV5, F3, GJB2, KCNC2, MGMT, PRDX1, PAX2, PENK, PPP5C, PRKAA1, PRKD1, RPS3, SLC8A1, SOD3, STAT6, STAU1, PRDX2, TRAF2, PRKRA, AKR1C3, KLF4, IL18BP, DHRS2 |
1694 | GO:0045664 | 0.00 | 1.66 | 51.33 | 71 | 177 | regulation of neuron differentiation | ABL1, ABL2, BIN1, APBB1, ARF1, BMP4, BMPR2, CACNA1A, CDC20, CHN1, CHRNB2, CNR1, CRX, BRINP1, DBN1, DNM2, DNMT3B, EFNA5, CTTN, EPHA3, EPHB3, EPOR, ETV5, PTK2B, FYN, GATA3, GOLGA4, RAPGEF1, GRID2, HGF, NRG1, IFNG, ILK, LIMK1, CAPRIN1, MAP1B, NRCAM, NTF4, NTRK2, NTRK3, P2RY2, PALM, PCP4, SERPINF1, PRKCI, PRKD1, PROX1, PTN, RAP1A, RAP2A, RARA, RARB, SALL1, SGK1, SNAP25, SOX5, SOX11, SRF, SYT1, SYT4, VEGFA, RNF112, LRP8, RND2, SF3A2, EOMES, SEMA7A, KLF4, RIMS2, CUL7, PQBP1 |
1695 | GO:1901362 | 0.03 | 1.66 | 17.79 | 25 | 67 | organic cyclic compound biosynthetic process | ATP1A1, SCARB1, AKR1C4, CYP3A4, CYP8B1, CYP11B1, CYP27B1, DHCR7, CYB5R3, FDFT1, FDPS, HMGCR, HMGCS2, HSD11B1, HSD17B3, HSD17B4, IDO1, OAT, PYCR1, QDPR, SQLE, SRD5A1, AKR1C3, ALDH4A1, GGPS1 |
1696 | GO:0003007 | 0.04 | 1.65 | 18.07 | 25 | 62 | heart morphogenesis | BBS4, BMP4, BMPR1A, COL2A1, S1PR1, EFNA1, ERG, GAA, HAS2, IHH, ILK, JUN, SMAD3, PTCH1, PTK2, RYR1, STIL, SLC8A1, SOX9, T, KDM6A, VEGFA, ADAM15, BAZ1B, COL4A3BP |
1697 | GO:0090092 | 0.01 | 1.65 | 31.90 | 44 | 109 | regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | ABL1, ACVR1B, ACVR2B, ACVRL1, XIAP, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, CAV3, DNM2, FBN1, FGF9, FOXD1, GATA4, GATA6, GDF9, GPC3, ONECUT1, RBPJ, ILK, ING2, INHA, SMAD3, SMAD6, SMAD7, MEN1, PDPK1, PPP1CA, RPS27A, SOX11, ADAM17, TTK, UBB, WNT1, LTBP4, CHRD, BMP15, ZFYVE9, ONECUT2, GDF15, ADAMTSL2 |
1698 | GO:0007219 | 0.01 | 1.65 | 33.36 | 46 | 114 | Notch signaling pathway | ADAM10, ANXA4, APP, ASCL1, CCNC, CDH6, CDK6, CDK8, CREB1, DTX1, EP300, ETV2, FCER2, B4GALT1, GMDS, HHEX, FOXA2, ONECUT1, RBPJ, IL2RA, KCNA5, KIT, LLGL2, PLN, RFNG, RPS19, RPS27A, SKP1, SNAI1, SOX9, STAT3, ADAM17, TBL1X, UBB, WNT1, IFT88, NR0B2, CUL1, SORBS2, TP63, NUMB, DLK1, ITGB1BP1, NR1H4, RBX1, RCAN2 |
1699 | GO:0040008 | 0.03 | 1.64 | 20.95 | 29 | 73 | regulation of growth | ACTL6A, AES, AGTR1, FXYD2, CDK11B, CTGF, E4F1, IGFBP3, IGFBP6, IHH, ING2, PRKCQ, SHC1, SPOCK1, TSG101, WRN, BAP1, LTBP4, BLZF1, RUVBL1, CREG1, WISP3, SOCS3, SOCS6, BCAR1, VPRBP, ARHGEF11, SGK2, RASGRP2 |
1700 | GO:0032970 | 0.00 | 1.64 | 55.31 | 76 | 189 | regulation of actin filament-based process | ABL1, ABL2, ADD1, ARF1, ARHGAP6, ATP1A1, ATP1A2, BBS4, BST2, CAPG, CAV3, CDK5, CNN2, CSF1R, CTGF, DAPK3, S1PR1, LPAR1, EFNA5, CTTN, EPHA3, EPHA5, PTK2B, GATA4, GPM6B, GRB2, HCLS1, HRG, ICAM1, ID1, ILK, JUP, KCNJ2, LIMK1, SMAD3, NTRK3, PAM, PDE4B, PFN2, PLN, PRKCE, PRKCQ, PROX1, RAC1, RYR2, SCN5A, CCL21, SDC4, SLC9A1, FSCN1, SPTA1, SPTB, STC1, TNNC1, TSC1, SUMO1, VIL1, WAS, WNT11, ARHGEF5, LATS1, ITGB1BP1, SLIT2, PICK1, BAG4, GMFG, PPM1F, SEMA3E, WDR1, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, ABI2, WASF2 |
1701 | GO:0042981 | 0.02 | 1.64 | 24.44 | 34 | 89 | regulation of apoptotic process | ACTN4, ACTN1, ALK, ALX3, BMP1, BMP3, BMP8B, CASP5, CASP10, CD3E, DBH, ETS1, FLT3, GAS1, GDF9, GRID2, TNFRSF9, INHA, PHB, SKP2, SP100, STK10, TNFRSF1A, TNFRSF1B, TRAF1, WRN, BMP15, GDF15, BCAR1, TRAF4, SLK, OXSR1, SGK2, FEM1B |
1702 | GO:0016477 | 0.01 | 1.64 | 31.74 | 44 | 114 | cell migration | ANG, ARF4, RERE, TSPO, CD151, VCAN, CSPG4, CTGF, ENPEP, EPHA3, EPHA4, EPHB3, ERG, EFEMP1, FUT8, HEXB, IL12B, ITGA7, JUP, LAMA3, LAMA4, PIK3C2A, PIK3C2B, PRKCI, PSG2, RAB1A, SCNN1B, SDC1, SGK1, SIX3, SLC9A1, FSCN1, TYK2, USP9Y, CUL3, SORBS2, UNC5C, PSTPIP1, CDC42BPB, SDC3, SLK, GAB2, ARPC5, ABI2 |
1703 | GO:0006259 | 0.02 | 1.64 | 24.60 | 34 | 86 | DNA metabolic process | ANXA1, CCNE1, CDC25A, CDC25C, TRDMT1, DNMT3B, E4F1, TYMP, GNAS, H3F3B, MKI67, NUP98, ORC1, ORC2, ORC4, PTMS, PURA, RAN, RBBP4, RBMS1, RLF, RRM1, RRM2, SET, SMARCA1, CDK2AP1, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, FKBP6, HIST1H3F, PICK1, GINS1 |
1704 | GO:0009166 | 0.05 | 1.64 | 16.68 | 23 | 57 | nucleotide catabolic process | ADA, ARNT, CAT, CNP, GPX1, HPRT1, IGF1, INS, NUDT1, NTHL1, P2RX7, PDE4B, PDE8A, PGAM1, PRKAA1, PRKAG1, STAT3, UNG, UPP1, OGT, PDE5A, MBD4, ENTPD4 |
1705 | GO:1901657 | 0.00 | 1.64 | 59.12 | 81 | 202 | glycosyl compound metabolic process | ACACB, ACPP, ADA, ADSS, AHCY, AK1, AK2, ALDOC, AMPD2, APRT, ARNT, ATP1A2, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V0A1, BAD, BPGM, TSPO, CDA, AKR1C4, COX8A, COX15, CTNS, DHODH, DLD, DLG2, DLG3, DNMT1, DNMT3A, DNMT3B, TYMP, ENO2, GAPDH, GNAI3, GPI, GUK1, HK2, HMGCR, HPRT1, IGF1, IMPDH1, IMPDH2, INS, LDHC, OGDH, P2RX7, PFKFB4, PGAM1, PGK2, PPP2R5D, PRKAA1, PRKAG1, PRPS2, PTGDR, SDHC, SLC34A1, SNCA, STAT3, SULT1E1, SULT1A3, SULT1C2, SULT2B1, TAZ, TYMS, UPP1, UQCRC1, UQCRC2, UQCRH, OGT, AKR1C3, PAPSS1, COX5A, ENTPD4, SLC25A13 |
1706 | GO:0060491 | 0.02 | 1.64 | 22.53 | 31 | 77 | regulation of cell projection assembly | AQP1, BBS4, KLF5, DNM2, DPYSL3, EPHA2, GPM6A, HRG, ICAM1, KIT, P2RX7, PALM, PFN2, PRKCQ, RAB5A, RAC1, RAC2, RALA, RAP1GAP, CCL21, FSCN1, SRF, CLRN1, WNT1, IFT88, SLIT2, NRXN1, ATG5, IFT140, ARPC2, WASF2 |
1707 | GO:0031667 | 0.01 | 1.63 | 31.97 | 44 | 111 | response to nutrient levels | ACACB, ACADS, ACAT1, ACTL6A, ATP6V0A1, BBS4, BNIP3L, CLPS, CPS1, CSNK2A2, CTSK, CYBA, DCN, DHODH, CTTN, G6PC, GCG, KAT2A, GHSR, GSS, HTR2C, IGF2, KDR, LIPC, PAX2, PIP4K2A, PROX1, PSPH, RPL28, SLC22A3, SORD, VDAC1, TRPV1, WNT11, ZBTB17, FZD5, IFT88, RUVBL1, SOCS3, SLIT2, RAB33A, FEZ2, RUBCN, HDAC6 |
1708 | GO:0018193 | 0.00 | 1.63 | 218.32 | 293 | 746 | peptidyl-amino acid modification | ABL1, ABL2, ACTL6A, ACVR1B, ADH5, ADRBK1, ALK, ANGPT1, APBB1, BIRC5, APLP2, APP, ARAF, ARCN1, ARF4, ARNT, ATR, AXL, BAX, BCR, BGLAP, BLK, BMI1, BMX, BRCA2, BTK, CALM3, CAMK2A, CANX, CCNB1, CD3E, CD4, CD36, CD40, CD44, CD59, CD74, CDK2, CDK5, CHEK1, CLK1, CLK3, COPA, COPB1, CSF1R, CSF2, CSNK1D, CSNK1G3, CSPG4, CTF1, CTH, DAD1, CD55, DCN, ACE, DHPS, DYNC1H1, DNMT1, DNMT3B, DPH2, PHC2, EFNA1, EFNA5, EGR2, EPHA2, EIF5A, EP300, EPHA3, EPHA4, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, ERCC6, EZH1, F2, F2R, F7, F10, PTK2B, EFEMP1, FCER1A, FGF7, FGFR3, FGR, FKBP3, FKBP5, FLT1, FLT3, FLT4, FUT8, FYN, GAPDH, GATA3, GCG, KAT2A, B4GALT1, GMDS, GOLGA2, GOLGB1, GRIA1, HIST1H1B, HCLS1, HGF, NRG1, UBE2K, HMBS, HNRNPC, HPX, HRC, HRG, PRMT1, ICAM1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF1R, IGF2, IL3, IL12B, IL12RB2, IL13, IL18, ILK, INCENP, INS, INSRR, ISL1, ITGA5, ITGB1, IVL, JARID2, KDR, KIT, SMAD7, MEN1, MGAT2, MGAT3, KITLG, MAP3K11, NTRK2, NTRK3, DDR2, NUP98, P4HA1, PCNA, PDPK1, PFN2, PPIB, PPID, PPP2R1A, PPP6C, PRKAA1, PRKCB, PRKCE, PRKCI, PRKD1, PRKCQ, PRKCSH, MAPK1, MAPK3, PRKX, PROC, PROS1, PTK2, PTPN2, PTPN6, PTPRZ1, RAB1A, RAB3B, RAB6A, RAD21, RAF1, RANBP2, RANGAP1, RAP2B, RET, RNF2, RPS6KA2, RYK, S100A8, S100A9, TRAPPC2, SET, SETMAR, SGK1, SHC1, SUMO3, SNCA, SNTA1, SOX4, SP3, SP100, UAP1, SPINK1, SPTA1, SPTB, SYK, ADAM17, TAF7, TAF10, TNFRSF1A, TOP1, TOP2A, TOP2B, TTK, TYK2, TYRO3, SUMO1, KDM6A, VEGFA, VEGFB, VRK1, VTN, WRN, PRDM2, LRP8, TUSC3, NUP214, AAAS, SMC1A, GFI1B, BCAR3, DYRK2, TPST2, TPST1, FKBP6, OGT, HAT1, STK16, RUVBL1, USO1, DYNLL1, TNKS, B4GALT4, B4GALT3, EED, RIPK1, RIPK2, TNFRSF18, DYRK4, DPM2, NRP1, PROZ, HERC2, P4HA2, RPS6KA4, TNFSF18, BAZ1B, UNC119, LATS1, SMC3, DYRK1B, ARHGEF2, AURKB, RPS6KA5, COPB2, GTF3C4, B4GALT6, COG1, EIF2AK3, ATG5, GOSR1, BAG4, SEC22B, GOSR2, CLOCK, AATK, NUP155, PPM1F, TTLL4, KDM4A, NUP93, VPRBP, SETD1A, RASSF2, SPOCK2, OXSR1, NR1H4, HDAC6, GNE, UBA2, SAE1, SGK2, AKAP9, ABI2, TRIM28 |
1709 | GO:0033365 | 0.00 | 1.63 | 153.35 | 207 | 524 | protein localization to organelle | ACTL6A, ADAR, AGTR2, ANGPT1, ARF4, ARL1, ARL2, ARNTL, RERE, ATR, ATRX, BAD, BAX, BBS4, BCL3, BICD1, BMP4, BMPR1A, BNIP3L, BRCA2, BUB1B, TSPO, CASP8, CBLB, CD36, SCARB2, CDH1, CDKN1A, CENPA, COL1A1, CSE1L, CSNK1D, CSNK2A2, CTSK, DDX1, DDX3X, DIAPH1, DKC1, EDA, EMD, F2R, FAU, FGF9, FYB, FYN, KAT2A, GFER, GNAQ, GOLGA4, GPR26, HIST1H1B, HCLS1, NRG1, HHEX, HK2, HNMT, HSPA4, HSPA9, IFNG, IGF1, IL10, IL12B, IL18, INS, JUN, JUP, KPNA1, KPNA2, KPNA3, KPNA4, IPO5, SMAD3, TONSL, YBX1, NUP98, PRDX1, PCM1, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PPM1B, PRKCQ, MAPK1, MAPK3, PSMB7, PSMD8, PTGS2, PEX19, PEX5, RAB6A, RAC2, RAD21, RAN, RANBP2, RB1, RNASE2, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, RYR2, SFRP5, STIL, SIX3, SLC9A1, SUMO3, SORL1, SOX9, SREBF1, SRP9, SRP14, SSR3, STAT3, SYK, TRIP6, TRPS1, TULP1, TULP2, TULP3, UBE2L3, SUMO1, VEGFA, WRB, YWHAH, YWHAZ, ZIC1, ZBTB17, FZD5, NUP214, AKAP1, BAP1, FZD7, DYRK2, OGT, AP3B1, RGS20, RUVBL1, AKR1C3, DYNLL1, TNKS, TNFSF14, IL18R1, NRP1, AP3D1, CDKL2, RPL14, ZW10, AURKB, VAPA, TRIP11, RPL23, SLC9A3R1, ZFYVE9, PEX16, EIF2AK3, AKAP6, CABP1, LITAF, BAG4, NUP155, IPO13, NUP93, CROCC, CEP57, IFT140, ZFYVE16, ATG13, SPCS2, TOMM20, KLHL21, FAM20B, MFN2, BCL2L11, PARP3, SAE1, ARFRP1, TRIM28, NUTF2 |
1710 | GO:0006402 | 0.00 | 1.62 | 39.51 | 54 | 135 | mRNA catabolic process | ZFP36L2, DDX6, EIF4A1, EIF4A2, EIF4B, EIF4E, FAU, EIF3E, CNOT2, CNOT4, EXOSC9, PPP2R1A, PPP2R2A, UPF1, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, SUPV3L1, PRPF18, KHSRP, RPL14, RPL23, GTPBP1, DHX34, EIF4A3, SMG7, RBM8A |
1711 | GO:0010629 | 0.02 | 1.62 | 23.98 | 33 | 85 | negative regulation of gene expression | ACACB, ACVR1B, BIRC3, XIAP, BARD1, BBS4, CCNB1, CD3E, CD28, CD59, CDKN1A, CCR1, CR1, CRH, CRYAB, CTGF, CD55, FLOT2, FYN, GAS1, INPPL1, SERPINE1, SERPINF1, PGR, RPS26, SRSF7, SFSWAP, VEGFB, PICALM, SRSF9, SLIT2, TMEM59, RNF40 |
1712 | GO:0033554 | 0.00 | 1.62 | 163.11 | 220 | 574 | cellular response to stress | ADD1, ALB, ANXA5, APAF1, XIAP, ASNS, ASS1, ATP2A1, ATRX, BARD1, BCL2A1, BCL3, BMPR2, BOK, BRCA2, CAPS, CDK3, CDKN1A, CHD2, CHUK, TPP1, COMT, COX8A, CREB1, CRHBP, CRKL, CSNK1D, CTH, CTLA4, CTNNA1, DDB1, DDX1, DDX11, DNMT3B, DUSP7, DUSP9, EPHA2, ELK1, EYA4, ERCC3, ERCC4, EXTL3, EYA2, FANCE, FANCB, FANCF, FANCG, FEN1, GABRA5, GFAP, GRB2, HAS2, HDGF, UBE2K, HK2, HMGN1, DNAJB2, HSPA6, ID2, IFI16, IFNG, INSIG1, IRAK2, ISL1, ITPR1, KPNA2, MKI67, FOXO4, NUDT1, TONSL, NTHL1, P2RX5, PCK1, PDK4, PEX13, PGK2, PPP2CB, PPP2R5D, PRKG1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RAD21, RAD23B, RAD51C, RAD51B, RAD51D, RBBP6, RBBP8, UPF1, REV3L, RFC1, RFC3, RFC4, RFC5, RHAG, RHCE, RHD, RPS6KA2, RXRA, SGK1, SHC1, SIPA1, SKP1, SLCO1A2, SLC22A3, SUMO3, SNRPD1, SNRPF, SOX4, SP100, SRD5A1, SRF, SSRP1, STAT2, STK10, SULT1A3, KLF10, TNFRSF1A, TNFRSF1B, TOP2A, NR2C2, HSP90B1, UBA7, UBE2E2, SUMO1, UFD1L, UNG, UPP1, UVRAG, WNT1, WRN, XPA, XRCC2, XRCC5, YY1, TRIM25, ZNF189, RNF103, CHAF1B, SMC1A, HIST1H4I, CDC45, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, DYRK2, CUL1, SMARCA5, PPM1D, PARG, IKBKG, COPS3, CDC14B, PEA15, CRADD, TNFRSF10B, ALKBH1, HERC2, MBD4, BAZ1B, ATP6V0D1, SMC3, EXO1, VAPB, RPS6KA5, COPS2, RECQL5, PICK1, CHST3, PSMF1, CHD1L, GOSR2, CLOCK, KDM4A, SLK, ATG13, RIMS3, PHYHIP, TATDN2, CUL7, RB1CC1, DCLRE1A, USP3, FGFBP1, REC8, PDCD6, PARP3, SH2D3C, SH2D3A, COL4A3BP, CTDSP2, RAD50, ALYREF, PSME3, PSMD14 |
1713 | GO:0010770 | 0.03 | 1.62 | 23.41 | 32 | 80 | positive regulation of cell morphogenesis involved in differentiation | BMPR2, COL1A1, DNM2, EFNA5, EPHA4, FGA, GDNF, GOLGA4, HAS2, NRG1, ILK, LIMK1, CAPRIN1, SMAD3, MAP1B, NTRK2, NTRK3, PAX2, RAC1, RAC3, SGK1, SNAI1, SRF, VEGFA, LRP8, RND2, SEMA7A, NRP1, ARHGEF7, SLIT2, CUL7, ARPC2 |
1714 | GO:0046129 | 0.05 | 1.62 | 17.56 | 24 | 60 | purine ribonucleoside biosynthetic process | ACACB, ADA, ADSS, AK1, AK2, APRT, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V0A1, GUK1, HPRT1, IMPDH1, IMPDH2, LDHC, PRPS2, STAT3, PAPSS1, SLC25A13 |
1715 | GO:1903363 | 0.05 | 1.62 | 17.56 | 24 | 60 | negative regulation of cellular protein catabolic process | BUB1, BUB1B, CCNB1, CDC20, CDC27, CENPF, CSNK2A1, CSNK2A2, DUSP1, MAD2L1, OPHN1, SMARCC1, TTK, UBE2D1, WNT1, ZNF207, CDC23, CDC16, USP14, ZW10, BUB3, PSMF1, BAG5, RGP1 |
1716 | GO:0046395 | 0.02 | 1.61 | 24.19 | 33 | 83 | carboxylic acid catabolic process | ACAT1, AHCY, ARG1, ASL, ASPA, ALDH7A1, AUH, BCAT2, BCKDHA, CDO1, SLC25A10, CTH, DAO, DBT, DLD, GAD1, GLDC, GLUD1, GPT, GSTZ1, HNMT, HPD, IDO1, OAT, OGDH, PAH, QDPR, RENBP, SHMT1, SUOX, TAT, DDO, KYNU |
1717 | GO:0097190 | 0.00 | 1.61 | 49.92 | 68 | 174 | apoptotic signaling pathway | ABL1, ANXA6, XIAP, ARHGAP4, ATF4, ATP2A1, BCL3, BNIP3L, BRCA2, BTK, CD3E, CD5, CD28, TNFRSF8, CD40, CD44, CD74, CDKN1A, CDKN2D, CRH, CTH, DDX5, EPHA2, EP300, ERCC6, FGD1, GCG, GRINA, HIC1, HIP1, UBE2K, HSPB1, IFI16, ING2, INS, ITPR1, JUN, OPA1, P2RX4, PTGIS, PTH, RAC1, DPF2, RPS27A, SCN2A, ITSN1, SNAI1, SOD2, SOS2, TPT1, TRIO, VAV1, VDAC2, WFS1, XPA, DYRK2, CUL4A, CUL3, CUL2, CUL1, ARHGEF7, VNN1, SGPL1, BAG5, PPM1F, ARHGEF11, PDCD6, TRAP1 |
1718 | GO:0001818 | 0.02 | 1.61 | 25.69 | 35 | 88 | negative regulation of cytokine production | ANGPT1, BST2, BTK, TSPO, CMKLR1, CRYBA1, FBLN1, GATA6, GHSR, IFNA2, IFNG, IL12B, IL13, TNFRSF9, IDO1, LTF, PCBP2, PPM1B, PRG2, RAC1, RPS27A, CX3CL1, SFTPD, SLAMF1, UBB, UBA7, WNT11, TRIM25, CD84, TAX1BP1, RPS6KA4, RPS6KA5, ATG5, NUTF2, PRG4 |
1719 | GO:0044093 | 0.04 | 1.61 | 18.20 | 25 | 66 | positive regulation of molecular function | ACTN4, ADD1, KRIT1, CTSS, EPB41, GATA3, KAT2A, IGF1, ISL1, KCNJ11, MEN1, NTSR1, RAN, RARA, RFNG, S100A1, SGK1, SLC9A1, VTN, NRP1, BAZ1B, SYNGR3, GSTO1, AKAP7, SGK2 |
1720 | GO:0014031 | 0.01 | 1.61 | 30.14 | 41 | 103 | mesenchymal cell development | BMPR1A, COL1A1, EDNRA, EDNRB, EFNA1, EFNB1, EPHA3, ERG, FGF8, GDNF, HAS2, HGF, NRG1, FOXA2, HPN, RBPJ, ISL1, SMAD3, SMAD7, KITLG, PAX3, MAPK1, MAPK3, RET, S100A4, SEMA3F, SNAI1, SOX9, SOX10, SOX11, WNT11, SEMA3B, EOMES, SEMA7A, ADAM15, NRP1, PHOX2B, SEMA3E, CUL7, ZEB2, TRIM28 |
1721 | GO:1901565 | 0.00 | 1.61 | 53.09 | 72 | 182 | organonitrogen compound catabolic process | ABAT, ACAT1, ADA, AHCY, ANPEP, ARG1, ASL, ASPA, ALDH7A1, AUH, BCAT2, BCKDHA, BHMT, BLVRA, CAT, SCARB1, CDA, CDO1, TPP1, COMT, SLC25A10, CTH, CTSH, CYP3A4, DAO, DBH, DBT, ACE, DHPS, DLD, TYMP, ENPEP, GAD1, GALC, GLDC, GLUD1, GM2A, GOT2, GPT, GPX1, GSTZ1, HNMT, HPD, HPRT1, IDO1, IVD, LIPC, LTA4H, NUDT1, NTHL1, OAT, OGDH, PAH, PDE4B, PDE8A, PPT1, QDPR, SAT1, SHMT1, SMPD1, SUOX, TAT, UNG, UPP1, XPNPEP1, DDO, PDE5A, ALDH4A1, SGPL1, MBD4, KYNU, ENTPD4 |
1722 | GO:0045893 | 0.00 | 1.61 | 42.53 | 58 | 151 | positive regulation of transcription, DNA-templated | AGTR2, BRCA2, BRDT, CCNE1, CD86, CDH1, CDK2, CDX2, CHEK1, COL1A1, DNM2, ERCC6, F2R, FGF7, HAS3, HMGN1, HNF4G, IFNA2, ILK, ING2, AFF1, PHB, PHF2, MAPK1, PSMD9, PTCH1, RAN, RET, RFXAP, RNF6, SMARCA1, SMARCD3, SNAI1, SRY, TBP, NR2F2, TNNI2, WNT11, YWHAH, ZBTB17, ZP3, ZXDA, FGF23, ARID1A, PICALM, FZD7, KLF7, BAZ1B, DYRK1B, TRIP4, NR1D1, CREB5, RNF14, ZNF516, ARHGEF11, NR1D2, YAF2, ALYREF |
1723 | GO:0043933 | 0.00 | 1.60 | 288.72 | 380 | 1000 | macromolecular complex subunit organization | ABCA1, ABL1, ABL2, ACACB, ACADS, ACAT1, ACTN4, ACTN1, ACVRL1, ADAR, ADD1, AP2B1, AGTR1, AHR, ALAD, BIN1, ANG, ANGPT1, ANXA5, ANXA6, APAF1, BIRC3, BIRC5, ARF1, ARG1, ARHGAP6, ARL2, ASL, ATP6V0A1, ATR, BAD, BAX, BBS4, BICD1, BIK, BLK, CAMK2G, CAPG, CASP8, CASQ1, CASQ2, CAT, CAV3, CD3E, CD3G, CD36, SCARB1, ENTPD2, CD40, CD59, CD74, CDA, CENPE, CENPF, CHRNB2, CHRNB4, CIRBP, AP2S1, CLU, CLNS1A, COL1A1, COL2A1, COL6A1, COL6A2, COL11A1, COX15, CLDN3, CREB1, CRYAB, CSF2, CSNK1D, CTGF, CTH, CTNNA1, CYBA, DARS, DBN1, DDX1, DDX3X, DDX6, DHPS, DIAPH1, DIAPH2, DNM1, DYNC1H1, DPYSL3, S1PR1, LPAR1, EFNA5, EIF5A, EML1, EMP2, CTTN, EPRS, EPS15, PTK2B, FAU, FGA, GFAP, GHSR, GJB1, GLRA1, GLRB, GOLGA2, GRB2, GRB7, GRIA1, HBA1, HBA2, HBE1, HCLS1, NRG1, HIP1, UBE2K, HMGCR, HPRT1, HRG, HSPA4, ICAM1, ID1, IGF1R, IL1RAP, IL2RB, TNFRSF9, ILK, IMPDH2, INS, INPPL1, INSIG1, EIF3E, IRAK1, EIF6, ITGB5, ITPR3, JUN, JUP, KCNA1, KCNA3, KCNA4, KCNA5, KCNC2, KCND2, KCND3, KCNJ2, KCNS1, KCNS2, KCNS3, KPNA3, IPO5, KRT9, KRT14, LCAT, LIMK1, LIPC, SMAD1, SMAD3, SMAD6, MYO1B, CNOT2, DDR2, NUP98, OAS1, OAT, OTX2, P2RX1, P2RX3, P2RX4, P2RX7, P4HA1, PAM, PCM1, CHMP1A, PFN2, PIK3C2A, PLN, PPID, PPP1CA, PPP2R1A, PPP2R1B, PPP6C, PRKCE, PRKCI, PRKCQ, PROX1, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD4, PSMD8, PSMD9, PSMD11, PTK2, PEX5, RAB1A, RAC1, RAC2, RAD51, RAD51C, RAD51B, RAD51D, RAF1, RAN, UPF1, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, RRM1, RRM2, CLIP1, RXRA, RXRG, SCO1, CCL21, SDC4, TRAPPC2, SELP, SRSF1, SRSF5, SFSWAP, SGK1, SH3BGR, SHMT1, SHMT2, STIL, SLC6A4, SLC9A1, SLC34A1, SLC22A1, SNAP25, FSCN1, SNRPC, SNRPD1, SNRPE, SNRPF, SNX2, SOD2, SORL1, SPTA1, SPTB, SRF, SRPK2, TRIM21, STXBP3, SYT1, TARBP2, TAZ, TBCD, HNF1A, GCFC2, TNFRSF1A, TP73, HSP90B1, TRAF1, TRAF2, TSC1, TTK, TUBG1, SUMO1, COL14A1, USP4, NR1H2, CLRN1, UVRAG, VBP1, VDAC2, VIL1, VIM, WAS, WNT11, XRCC2, ZNF148, ZNF207, ARHGEF5, FOSL1, IFT88, SF3A2, CLPP, SMC1A, PICALM, CUL3, SORBS2, GAS7, PRPF18, USO1, TNKS, EIF3F, EIF3G, SRSF9, DGAT1, TRADD, RIPK1, HRK, SNAP23, PEX11B, LIN7A, SYNJ1, RPL14, CLDN1, LATS1, SMC3, PRPF3, SCAF11, ARHGEF2, ZW10, REPS2, ITGB1BP1, SNAP29, RPL23, SLIT2, SLC9A3R1, KIF3B, ZFYVE9, NRXN1, GRHPR, LIPG, DDX23, EIF2AK3, PICK1, ADAMTS3, ADAMTS2, BAG4, GMFG, SEC22B, BCAR1, GOSR2, PDE4DIP, NUP93, CEP57, KNTC1, SLK, PIEZO1, CKAP5, TOMM20, DNAJC6, SNAP91, KIAA0196, WDR1, BCL2L11, PARP3, RANBP9, SMC4, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, FRY, AKAP9, ABI2, TRIM28, WASF2 |
1724 | GO:0008037 | 0.04 | 1.60 | 21.36 | 29 | 73 | cell recognition | APP, CD5, CD6, CD36, SCARB1, CNR1, VCAN, EPHA3, EPHA4, EPHB1, EPHB2, EPHB3, FCN2, B4GALT1, HIST1H1T, MFGE8, CD200, NRCAM, OVGP1, PTPRZ1, PVR, CCL21, SPAM1, CNTN2, TULP1, ZAN, ZP3, FCN3, NRP1 |
1725 | GO:0035304 | 0.04 | 1.60 | 21.36 | 29 | 73 | regulation of protein dephosphorylation | AGTR2, CALM3, CRY2, DLG2, DLG3, ENSA, GPLD1, HPN, IFNG, ITGA1, ITGA2, SMAD3, PPP1R12A, PPP1R7, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, SET, SMPD1, HSP90B1, TSC1, AKAP1, RGN, AKAP6, BAG4, SFI1, NUAK1, FARP1 |
1726 | GO:0046916 | 0.05 | 1.60 | 18.44 | 25 | 63 | cellular transition metal ion homeostasis | ABCB7, ALAS2, APLP2, APP, ARF1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, FTL, HPX, IREB2, LTF, NUBP1, S100A8, S100A9, SCO1, SLC30A1, SLC30A2, AP3D1, ATP6V0E1, ATP6V0D1, ATP6V1G1, ABCB6 |
1727 | GO:0035239 | 0.02 | 1.59 | 27.30 | 37 | 94 | tube morphogenesis | ACVRL1, APAF1, BBS4, CASP8, CSF1R, EDA, EFNB2, EPHA4, FGF3, FZD2, GATA3, GATA6, KAT2A, RBPJ, OPA1, PAX3, PRKACB, PRKX, RALA, RARA, RET, RYR2, SDC4, STIL, SOX4, ST14, T, TSC1, TULP3, KDM6A, FZD3, ARID1A, FZD6, ITGB1BP1, HAND1, ZEB2, BCL2L11 |
1728 | GO:0044242 | 0.03 | 1.59 | 23.66 | 32 | 81 | cellular lipid catabolic process | ACACB, ACADM, ACADS, ACOX1, ABCD1, SCARB1, CNR1, CPT1B, CPT2, CRAT, ECH1, EHHADH, ETFA, ETFDH, FAAH, GALC, GM2A, HADHA, HEXB, HSD17B4, IDH1, IVD, PEX7, PEX13, PPT1, ABCD3, SMPD1, ACOX3, CYP4F2, AKR1C3, SGPL1, LIPG |
1729 | GO:0034220 | 0.00 | 1.59 | 153.00 | 204 | 528 | ion transmembrane transport | ABCA1, ACACB, ANXA5, ANXA6, AQP1, AQP5, AQP6, ATP2A1, ATP2B1, ATP2B2, ATP2B3, ATP4B, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, CACNA1A, CACNA1B, CACNB1, CACNB2, CACNB4, CACNG1, SLC25A20, CASQ1, CASQ2, CAV3, CHRNB2, CHRNB4, CLCA1, CLCN2, CLCN3, CLCN6, CLCN7, CLCNKA, CLCNKB, CNGA1, CNGA2, COX6A1, COX6B1, COX7A1, COX7B, COX7C, COX8A, COX15, CPT1B, CPT2, CRHBP, CYB5A, CYBA, DIAPH1, DRD3, TSC22D3, PTK2B, GABRA4, GABRA5, GABRB2, GABRE, GABRG1, GABRR1, GABRR2, GLRA1, GLRB, GPM6A, XCR1, GRIA1, GRIA4, GRID1, GRID2, GRIN2A, HPN, HRC, HTR2C, ITGAV, ITPR1, ITPR3, KCNA1, KCNA3, KCNA4, KCNA5, KCND2, KCND3, KCNJ1, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN4, KCNS1, KCNS2, KCNS3, P2RX1, P2RX3, P2RX4, P2RX5, PDE4B, PIK3C2A, FXYD3, PLN, PRKAB2, PRKCE, PRKD1, PTPN3, PTPN6, RAF1, REST, RHAG, RHCE, RHD, RPS27A, RYR1, SCN1A, SCN2A, SCN2B, SCN4B, SCN5A, SCN7A, SCN8A, SCNN1A, SCNN1B, SCNN1G, CCL21, SGK1, SLC1A6, SLC4A1, SLC6A6, SLC6A7, SLC6A8, SLC7A1, SLC7A4, SLC8A1, SLC8A3, SLC9A2, SLC9A3, SLC12A1, SLC12A2, SLC13A1, SLC20A1, SLC20A2, SLC22A3, SLC22A2, SLC22A5, SNTA1, SPINK1, TRPC3, TRPC4, TRPC5, TRPM2, UBB, UQCRC1, UQCRFS1, UQCRH, VDAC1, VDAC2, TRPV1, YWHAH, SLC30A1, SLC30A2, KCNAB1, SLC7A5, KCNAB2, SLC25A12, RIPK1, SLC5A6, ATP6V0E1, ATP6V0D1, SLC16A6, SLC16A5, KCNAB3, SLC9A3R1, SLC22A8, COX5A, NRXN1, KCNK6, ATG5, SLC4A7, ATP6V1G1, PIEZO1, ATP2C2, OXSR1, WDR1, SLC12A6, HCN4, ABCC9, KCNK7, SGK2, SLC25A13, SLC25A15, SLC35B1, KCNMB2 |
1730 | GO:0031669 | 0.04 | 1.59 | 20.72 | 28 | 71 | cellular response to nutrient levels | ALB, ASNS, ATF3, ATF4, BMPR2, CDKN1A, COMT, ICAM1, IFI16, JUN, PCK1, PDK4, PRKAA1, RHAG, RHCE, RHD, SRD5A1, SREBF1, KLF10, TSC1, UPP1, WRN, PPM1D, AKR1C3, EIF2AK3, PICK1, ATG5, ATG13 |
1731 | GO:0048583 | 0.04 | 1.59 | 19.67 | 27 | 76 | regulation of response to stimulus | ATF4, CDK6, CHEK1, CRYAB, DHFR, FUT8, GABRA4, HP, HSBP1, NUP98, PPP4C, DNAJC3, PYCR1, RAD51, RANBP2, RPA2, RPA3, DNAJC7, VIL1, NUP214, AAAS, CUL4A, TRIP12, BAG3, BAG2, NUP155, NUAK1 |
1732 | GO:0048863 | 0.01 | 1.58 | 40.81 | 55 | 140 | stem cell differentiation | BMP4, BMPR1A, ZFP36L2, RUNX2, COL1A1, EDNRA, EDNRB, EFNA1, EFNB1, ELAVL1, EPHA3, ERG, ETV4, FGF8, GDNF, GPM6A, HAS2, HGF, HHEX, FOXA2, HOXD4, HPN, JARID2, KIT, SMAD3, SMAD7, KITLG, FOXO4, CNOT2, NTF4, PAX2, PAX3, MAPK1, MAPK3, PSMD11, RET, S100A4, SEMA3F, SNAI1, SOX5, SOX9, SOX10, SOX11, WNT11, SEMA3B, SEMA7A, TP63, ADAM15, NRP1, PHOX2B, PUM1, SEMA3E, CUL7, ZEB2, TRIM28 |
1733 | GO:0048522 | 0.00 | 1.58 | 49.00 | 67 | 195 | positive regulation of cellular process | ACTL6A, ADGRB2, BBS4, BCR, BICD1, CASQ2, CSNK2A2, CTSK, CTSS, DPP6, EPHA2, CTTN, EPHB1, EPHB2, EPHB3, GPM6A, GPR26, FFAR3, HNMT, KCNC2, KCNH2, KCNJ2, KCNJ11, KCNQ1, KPNA1, IPO5, ATXN3, CNOT2, PFDN2, PPT1, PROS1, RALA, RNASE2, RPL28, CLIP1, RYR2, S100A1, SFTPD, SLC34A1, FSCN1, SORL1, STC1, SURF4, TPBG, TULP1, CLRN1, WAS, SLC30A2, BAP1, PIK3R3, RUVBL1, CDKL2, NRXN3, AKAP7, GMFG, FRMPD4, C2CD5, FAM20B, WDR1, SAE1, ARPC5, ARPC1B, ACTR3, ACTR2, ABI2, WASF2, NUTF2 |
1734 | GO:0000819 | 0.02 | 1.58 | 28.97 | 39 | 99 | sister chromatid segregation | ATRX, BUB1, BUB1B, CCNB1, CDC6, CDC20, CDC27, CENPE, CENPF, CSNK2A1, CSNK2A2, DDX11, DUSP1, KIF25, MAD2L1, CHMP1A, PPP2R1A, PTEN, RAD51C, RB1, SFPQ, TOP2A, TOP2B, TTK, UBE2D1, ZNF207, SMC1A, CUL3, TNKS, CDC23, CDC16, LATS1, SMC3, ZW10, BUB3, CEP57, DLGAP5, REC8, SMC4 |
1735 | GO:0051222 | 0.01 | 1.57 | 38.72 | 52 | 133 | positive regulation of protein transport | ACTL6A, BMP4, BMPR1A, CDH1, CDK5, CHRM1, CSNK2A2, CTSK, EDA, EMD, KAT2A, GPR26, HCLS1, NRG1, HNMT, IL12B, IL18, JUP, KPNA1, IPO5, SMAD3, OAZ1, OAZ2, PCM1, PSMB7, PSMD8, PTGS2, RAC2, RNASE2, RPL28, SLC9A1, SORL1, TRIP6, TSG101, UBE2L3, ZIC1, ZBTB17, FZD5, ARHGEF5, BAP1, RUVBL1, TNFSF14, IL18R1, CDKL2, ITGB1BP1, AKAP6, ATG13, C2CD5, FAM20B, SAE1, TRIM28, NUTF2 |
1736 | GO:0006468 | 0.01 | 1.57 | 31.78 | 43 | 116 | protein phosphorylation | ADAM10, BIRC5, BUB1, BUB1B, CDK11B, CDK3, CDK6, CDK8, CSNK2A1, CSNK2A2, CTSG, ERCC3, ERG, FYB, GUCY2C, GUCY2F, GUCY2D, LIMK1, LIMK2, LIPE, SMAD9, PDK4, PHKA2, PHKB, PHKG1, PRKG1, PSKH1, RARA, RPS6KB1, RPS6KB2, SRPK2, STAT4, TRIO, PRKRA, RIOK3, CDKL1, CDKL2, DCLK1, STK17A, PICK1, CDC42BPB, NUAK1, COL4A3BP |
1737 | GO:0035556 | 0.00 | 1.57 | 68.38 | 92 | 251 | intracellular signal transduction | AGTR2, APAF1, APBB2, ATF4, ATP2A1, AVPR2, BCL2A1, BLK, BMX, BTK, CAPS, CBLB, CD14, CD86, CREB1, CRYAB, CTSH, DGKB, DAPK3, EIF4EBP2, ELK1, FYB, GUCY2C, GUCY2F, GUCY2D, UBE2K, NR4A1, ITGAV, ITPR3, KCNH2, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, FOXO4, OXTR, PIK3C2A, PI4KA, PPP2R5D, PRKACB, PRKACG, PRKAR1A, PRKAR2A, PRKAR2B, PRKCI, PRKCSH, PTAFR, RBM4, RGS12, RPS6, RPS6KA1, RPS6KA2, RPS6KA3, RYR1, S100A1, SCN2A, SGK1, SRPK2, STK10, NR2C2, TUFT1, TYK2, TYROBP, LAT2, XPA, SCG2, ANP32A, NSMAF, CUL4A, CUL2, DGKE, DYNLL1, ADAM15, RGS9, RPS6KA4, LATS1, DCLK1, RPS6KA5, STK17B, STK17A, AKAP7, CDC42BPB, PPM1F, SLK, RB1CC1, GAB2, NUAK1, OXSR1, ZBTB33, TANK, SGK2 |
1738 | GO:0034655 | 0.00 | 1.57 | 65.11 | 87 | 223 | nucleobase-containing compound catabolic process | ADA, AHCY, ARNT, ZFP36L2, CAT, ENTPD2, CDA, CNP, DDX6, TYMP, EIF4A1, EIF4A2, EIF4B, EIF4E, FAU, FEN1, GPX1, HPRT1, IGF1, INS, EIF3E, NUDT1, CNOT2, CNOT4, NTHL1, P2RX7, PDE4B, PDE8A, PGAM1, EXOSC9, PPP1R8, PPP2R1A, PPP2R2A, PRKAA1, PRKAG1, UPF1, RNASE2, RNASE3, RNASE6, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, STAT3, SUPV3L1, UNG, UPP1, OGT, PRPF18, KHSRP, RNASET2, PDE5A, MBD4, RPL14, RPL23, GTPBP1, ENTPD4, DHX34, EIF4A3, SMG7, RBM8A |
1739 | GO:1901575 | 0.00 | 1.57 | 47.68 | 64 | 169 | organic substance catabolic process | ACACB, ACADM, ACADS, ACOX1, ADH5, ABCD1, ALDOC, APOH, ARNT, STS, BAD, BPGM, DAGLA, ENTPD2, CLPS, CNP, CNR1, CPT1B, CPT2, CRAT, CYP1A2, CYP2A6, ECH1, EHHADH, ENO2, ESD, ETFA, ETFDH, FAAH, FABP2, FABP7, FUT6, FUT8, GALE, GAPDH, GPI, HADHA, HK2, HSD17B4, IDH1, IGF1, LIPA, LIPE, OXCT1, PEX7, PEX13, PFKFB4, PGAM1, PGK2, PPP2R5D, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKCE, ABCD3, RENBP, RPE, STAT3, YWHAH, ACOX3, OGT, LIPG, XYLB |
1740 | GO:0030001 | 0.00 | 1.56 | 79.49 | 106 | 277 | metal ion transport | ANXA5, ANXA6, AQP1, ATP1A3, ATP12A, ATP2A1, ATP2B1, ATP2B3, ATP4A, ATP4B, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, CACNA1A, CACNG1, CDK2, CDK5, CHRNB2, CLCA1, CLTC, CNGA1, CNGA2, CTGF, CYP27B1, FTL, FYN, GIF, GJA4, GPM6A, XCR1, GRIN2A, HPN, HTR2C, IREB2, ITGAV, ITPR1, ITPR3, KCNA1, KCNA3, KCNA4, KCND2, KCND3, KCNJ3, KCNJ5, KCNJ6, KCNJ8, KCNJ9, KCNJ10, KCNJ11, KCNJ14, KCNJ16, KCNK2, KCNK3, KCNN4, KCNS3, PRKCB, REST, RYR1, SCN1A, SCN2A, SCN7A, SCN8A, SCNN1A, SCNN1G, SCO1, CCL21, SLC5A2, SLC6A8, SLC8A3, SLC9A2, SLC10A1, SLC12A1, SLC12A2, SLC13A1, SLC34A1, SLC20A1, SLC20A2, SLC22A5, TPT1, TRPC5, TRPM2, TSC1, VDAC1, VDR, TRPV1, SLC30A2, TUSC3, PICALM, SLC5A6, ATP6V0E1, SLC13A2, ATP6V0D1, KCNAB3, RAB11B, KCNK6, SLC4A7, ATP6V1G1, ATP2C2, SLC12A6, HCN4, ABCC9, KCNK7, KCNMB2, RAMP3 |
1741 | GO:0009163 | 0.04 | 1.56 | 21.66 | 29 | 74 | nucleoside biosynthetic process | ACACB, ADA, ADSS, AK1, AK2, APRT, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V0A1, CDA, DHODH, TYMP, GUK1, HPRT1, IMPDH1, IMPDH2, LDHC, PRPS2, STAT3, TYMS, UPP1, PAPSS1, SLC25A13 |
1742 | GO:0034654 | 0.00 | 1.56 | 610.67 | 765 | 2107 | nucleobase-containing compound biosynthetic process | ABCA1, ABCA2, ABL1, ACTN4, ACTL6A, ACTN1, ACVR1B, ACVR2B, ADAM8, ADCY1, ADCY7, ADCYAP1R1, AEBP1, AES, AGTR2, NR0B1, AHR, ALK, ALX3, AMPD1, AMPD2, ANG, ANXA3, ANXA4, APBB1, APBB2, XIAP, BIRC5, APP, AQP1, ARF4, PHOX2A, ARNT, ARNTL, ASCL1, ASCL2, ATF3, ATF4, RERE, ATRX, AVPR2, BACH1, BCL3, BCL9, PRDM1, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTK, CALM3, CAMK2A, CAT, RUNX2, CBL, CCNC, CCNE1, CCNT2, CD3D, CD28, CD86, TNFSF8, CD36, CD40, CDK11B, CDC6, CDH1, CDK2, CDK5, CDK8, CDX2, CEBPE, CEBPG, CENPB, CHD2, CHD4, CHEK1, CHUK, CLU, CMKLR1, COL1A1, COX6A1, COX6B1, COX7B, COX7C, COX8A, CREB1, CRH, CRX, CRY2, CSNK2A1, CSNK2A2, CSTF3, CTH, CTNND1, CTNND2, DAPK3, DBP, DCN, DDX1, DDX3X, DDX5, DHFR, DLX5, DNM2, DNMT1, DNMT3A, DNMT3B, DRD3, DRD5, ARID3A, ATN1, RCAN1, TSC22D3, DTX1, E2F5, E2F6, E4F1, EBF1, ECM1, EDA, S1PR1, LPAR1, EDNRA, EDNRB, EFNA1, CELSR2, EGR2, EGR3, EGR4, EIF4A2, ELAVL2, ELF1, ELF3, ELK1, ELK3, EMX1, EMX2, EN1, EP300, EPHA5, EYA4, ERCC3, ERCC6, ERF, ERG, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA2, EZH1, F2R, FAU, FBN1, EFEMP1, FGF4, FGF7, FGF8, FGF9, FGFR3, FOXD1, FLII, FSHB, FSHR, NR5A2, FZD2, GALR1, GARS, GATA3, GATA4, GATA6, GCG, KAT2A, GDF9, GDNF, GHRHR, GPC3, GLO1, GMDS, GNAI3, GNAS, GPI, GPX2, GSC2, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GUCY2D, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, H3F3B, HAS3, HBE1, HCLS1, HDGF, HEXB, NRG1, HHEX, HIC1, HIP1, HIVEP2, HLF, HMGN1, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD4, HOXD8, HOXD9, HOXD10, HOXD12, HPN, PRMT1, HSBP1, HSF4, HTR2C, ICAM1, ID1, ID2, IFI16, SP110, IFNA2, IFNG, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL10, ILK, ING2, INS, INSIG1, IRAK1, ITGA6, IRAK2, IRF1, IRF5, ISL1, JARID2, JUN, JUNB, JUND, JUP, KIT, LMO1, LTF, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MEOX2, CIITA, ATXN3, AFF1, FOXO4, PPP1R12A, DRG1, TONSL, CNOT2, NRF1, YBX1, NTRK2, NTRK3, DDR2, NUP98, OAS1, ORC1, ORC2, OTX1, OTX2, OVOL1, P2RY11, PA2G4, PRDX1, SERPINE1, PALM, PAM, PAX2, PAX3, PAX9, PCK1, CHMP1A, PDE8A, PDPK1, PEG3, PFAS, PGR, PHF2, PIM1, PPID, PPP1R8, PPP2R1A, PPP5C, PRIM2, PRKAA1, PRKAB2, PRKAG1, PRKAR1A, PRKCB, PRKCI, PRKD1, PROX1, PRPSAP1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD9, PTAFR, PTCH1, PTEN, PTGIS, PTH, PTMA, PTPN14, PURA, PURB, RAD21, RAF1, RAN, RANBP2, RARA, RARB, RB1, RBBP4, RBBP8, RBL2, RCVRN, DPF2, REST, RET, RFX1, RFX3, RFX4, RFXAP, RGS12, RHEB, RLF, RNF2, RNF6, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS6KA1, RPS6KA3, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RRM1, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A12, SALL1, SATB1, ATXN7, XCL1, TRAPPC2, SET, SFPQ, SFRP5, SRSF1, SRSF5, SRSF7, SFSWAP, SGK1, SHMT1, SIAH2, SIM2, SIX3, SLC9A1, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCD3, SMARCE1, SNAI1, SNAPC3, SNAPC4, SNCA, SNRPE, SNRPF, SOD2, SOX3, SOX4, SOX5, SOX9, SOX10, SOX11, SP1, SP2, SP3, SP100, UAP1, SPIB, SREBF1, SRF, SRY, TRIM21, SSRP1, STAT2, STAT4, STAT5B, STAT6, SYK, T, TAF4B, TAF7, TAF10, TAL1, TARBP1, TARBP2, TBL1X, TBP, HNF1A, GCFC2, ZNF354A, PRDX2, NR2F1, NR2F2, KLF10, NR2E1, TMPO, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TRPS1, TSC1, TSG101, TTF1, TULP3, TNFSF4, UBE2D1, UBE2D2, UBE2L3, UBE2V1, UBE3A, SUMO1, UCP1, SCGB1A1, NR1H2, USF1, VAV1, VDR, VEGFA, VIP, VIPR2, WFS1, WNT1, WNT11, XRCC5, YY1, YWHAH, YWHAZ, ZFP37, ZFPL1, ZFX, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF33B, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF221, ZNF91, ZNF99, ZNF124, ZNF131, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF208, ZNF214, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZP3, ZXDA, PRDM2, LRP8, FZD5, MAFK, ARHGEF5, NUP214, FOSL1, FGF23, AAAS, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, USP9Y, ARID1A, HIST1H4I, PICALM, CDC45, EOMES, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NR0B2, UTF1, CUL3, CUL2, TTF2, KLF11, SMARCA5, OGT, IKBKG, IKBKAP, HAT1, GAS7, PIR, FCN3, BLZF1, KHSRP, STK16, RGS20, RUVBL1, KLF7, TP63, CHRD, DYNLL1, SRSF9, TRADD, EED, RIPK1, RIPK2, SUCLG1, CREG1, SAP30, HESX1, PER3, TAX1BP1, BUD31, PHOX2B, FUBP3, KYNU, HIST1H3F, HIST1H2AG, RPS6KA4, TNFSF18, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, RPL14, USP2, PDLIM1, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, DDX21, BMP15, CCPG1, RPS6KA5, ITGB1BP1, ZNF235, COPS2, TRIP11, HMGN3, TRIP4, GTF3C5, GTF3C4, GTF3C3, RPL23, COX5A, RECQL5, ZRANB2, HAND1, ZNF264, EIF2AK3, FHL5, AKAP6, ATG5, ONECUT2, LITAF, TBPL1, ZNF254, CIR1, GABBR2, NR1D1, CLOCK, SOX13, RBM39, CREB5, AKAP12, RNF14, GUCA1C, NUP155, PPM1F, ZNF516, SAFB2, PHF14, KDM4A, VGLL4, NUP93, BZW1, ST18, ZNF646, VPRBP, USP34, SETD1A, ZNF536, ZFYVE16, DHX38, RB1CC1, ARHGEF11, ZEB2, ZBTB24, ZNF518A, RNF10, ZBTB5, RBM8A, NR1I3, NR1H4, NR1D2, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, PQBP1, ZNF263, YAF2, TRIM28, ZNF197, ZNF256, ALYREF, RNF41, OLIG2, DENND4A, IRX5, RAMP3 |
1743 | GO:0016053 | 0.00 | 1.56 | 51.80 | 69 | 177 | organic acid biosynthetic process | ABAT, ACACB, ACADM, AHCY, ALDH1A3, ALOX15B, ANXA1, ASL, ASNS, ASPA, ASS1, BCAT2, BHMT, CBR1, CD74, CDO1, AKR1C4, CPS1, VCAN, CSPG4, CTH, CYP8B1, DCN, DHFR, DHPS, FCER1A, GAD1, GATM, GGT7, GLUD1, GOT2, GPT, HPGD, HSD17B4, IDO1, INSIG1, LDHC, LIPC, LTA4H, OAT, PAH, PDK4, PRKAA1, PRKAB2, PRKAG1, PROX1, PSPH, PTGIS, PTGS1, PTGS2, ABCD3, PYCR1, RBP1, ACSM3, SHMT1, SHMT2, ELOVL4, SYK, NR1H2, UROS, AKR1C3, ALDH4A1, KYNU, RGN, GSTO1, NR1D1, NR1H4, UST, DHRS9 |
1744 | GO:0019637 | 0.00 | 1.56 | 148.09 | 195 | 507 | organophosphate metabolic process | ABCA1, ACACB, ACPP, ADA, ADCY1, ADCY7, ADSS, AK1, AK2, ALDOC, AMPD1, AMPD2, APRT, AQP1, ARF1, ARNT, ATP1A2, ATP2B2, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V0A1, AVPR2, BAD, BPGM, TSPO, CACNB4, CAT, SCARB1, ENTPD2, CDA, CHAT, CHKA, CHKB, CKM, CNP, COX8A, COX15, CPS1, CRH, CSF1R, CTNS, DBI, DHFR, DHODH, DLD, DLG2, DLG3, DRD3, DRD5, TYMP, LPAR1, EDNRA, EDNRB, ENO2, EPHA8, FDFT1, FDPS, FGF7, FGFR3, FGR, FLT1, FLT3, FSHR, FZD2, G6PC, GALR1, GAPDH, GARS, GATA6, GCG, GHRHR, GK2, GNAI3, GNAS, GPD2, GPI, GPLD1, GPX1, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GUK1, GUCY2D, HADHA, HEXB, HK2, HMGCR, HPRT1, HTR2C, IDH1, IFNG, IGF1, IMPDH1, IMPDH2, INS, KIT, LCAT, LDHC, LIPC, MDH2, NUDT1, NTHL1, NTRK2, OAS1, OGDH, P2RX7, P2RY11, PALM, PCYT1A, PDE4B, PDE8A, PFAS, PFKFB4, PGAM1, PGD, PGK2, PIK3C2A, PIK3C2B, PI4KA, PIP4K2A, PPP2R5D, PRKAA1, PRKAG1, PRPS2, PRPSAP1, PTGIS, PTH, PTGS2, PTK2, RAC1, RAF1, RCVRN, RPE, RRM1, RRM2, CCL21, SDHC, SHMT1, SMPD1, SORD, STAT3, SULT1E1, SULT1A3, SULT1C2, SULT2B1, TAZ, TYMS, UNG, UPP1, UQCRC1, UQCRC2, UQCRH, VEGFA, VIP, VIPR2, WFS1, ZP3, PDHX, OGT, PIK3R3, KCNAB2, DGKE, PDE5A, DGAT1, SUCLG1, DPM2, MBD4, KYNU, PAPSS1, KLF4, COX5A, LIPG, GGPS1, AKAP6, PIGL, TBPL1, TP53I3, GABBR2, ENTPD4, AKAP12, GUCA1C, RUBCN, PTDSS1, XYLB, PIGK, SLC25A13 |
1745 | GO:0006915 | 0.01 | 1.55 | 37.93 | 51 | 140 | apoptotic process | ADD1, AHR, ALOX15B, BMX, BUB1B, CD5L, TNFSF8, CDK11B, CDH1, CSE1L, CSNK2A2, DFFB, DNASE1, DNASE1L3, EIF5A, FNTA, GAS2, GZMH, IAPP, IFNA2, IRF1, KPNA1, PAEP, PAX3, PEG3, PRKCB, PRKCE, PRKD1, MAPK1, MAPK3, PTPN6, PTPRH, RAD21, SATB1, SFRP5, SHB, VDAC1, VIM, FZD5, AIMP2, DPF1, OGT, IKBKG, TNFSF9, RABEP1, BCL7C, BCL7B, LITAF, BRE, MFN2, PDCD6IP |
1746 | GO:0044237 | 0.02 | 1.55 | 25.67 | 35 | 111 | cellular metabolic process | ALDH1B1, ALPI, ALPPL2, ARL1, ARL2, CA1, CA4, CA6, COX7A1, CYC1, DGKB, GALK2, GNB2, GNG10, FFAR1, FFAR3, ITPR1, ITPR3, KCNC2, KCNJ11, KCNS3, PRG2, SAT1, SCO1, SLC2A2, SLC20A1, SNAP25, SYT5, UQCRFS1, CES2, PCSK7, DGKI, PPIP5K1, FAM20B, DHRS2 |
1747 | GO:0043603 | 0.04 | 1.55 | 22.44 | 30 | 78 | cellular amide metabolic process | ACACB, ARG1, ARG2, ASL, ASNS, ASS1, CPS1, DHFR, DLD, SARDH, GALC, GM2A, HEXB, HLCS, P2RX1, P2RX7, PPP2R1A, PTGIS, PTGS2, SHMT1, SHMT2, SMPD1, STAT5B, TYMS, UGT8, VNN2, VNN1, SGPL1, SLC5A6, COL4A3BP |
1748 | GO:0048856 | 0.00 | 1.55 | 77.92 | 105 | 325 | anatomical structure development | ACP2, ALK, ARF1, ARSE, ASTN1, BCHE, DAGLA, CBLB, CD40, CDC20, CHRM1, CHRM3, TBCB, CLC, CMKLR1, CNR1, COX7B, BRINP1, DBN1, DDX6, DIAPH2, DLG2, DNASE1L3, DNMT3B, DRD3, ATN1, RCAN1, EIF2B1, ELAVL1, ELAVL3, EXTL1, FGF11, GABRA4, GJB1, GLRB, GSS, IL11RA, IDO1, JUND, KCNJ10, MAL, MATN3, ATXN3, OMP, CLDN11, P2RX5, PRDX1, PCP4, PENK, SERPINI1, PPP2R1A, PPP2R5D, PRM2, PURA, S100A8, S100A9, SCN2A, SCN2B, CCL21, SDHA, TRAPPC2, SMARCE1, SMPD1, SNAP25, SORL1, SPG7, SPOCK1, STRN, TAF4B, TARBP2, TPBG, SUMO1, UFD1L, UNG, TRPV1, ZNF24, RNF112, ZNF217, RNF103, MAFK, SLC7A5, SF3A2, DPF1, SOX14, PDE5A, JRKL, RGS9, VNN2, EIF2B3, BSN, RNF8, PAPSS1, EXO1, VAPA, NRXN2, IL27RA, ADAMTS4, BAG5, SPAG6, CEP57, ZNF536, SPOCK2, KIAA0319, KIAA0196, RNF10 |
1749 | GO:0050707 | 0.04 | 1.55 | 22.53 | 30 | 77 | regulation of cytokine secretion | ABL1, ABL2, AGTR2, ALOX15B, ANGPT1, ANXA1, ANXA4, CASP5, CD14, CD58, CRP, CSF1R, F2R, FBLN1, FGR, GATA3, IFNA2, IFNG, IL1A, IL10, TNFRSF9, INS, P2RX7, PAEP, CX3CL1, SYK, TNFSF4, IL1RL1, ATG5, NR1H4 |
1750 | GO:0016311 | 0.00 | 1.55 | 63.39 | 84 | 217 | dephosphorylation | ACP1, ACP2, ACPP, ALPI, ALPPL2, ATP1A1, BPGM, CAMK2G, CDC25A, CDC25C, CRY2, DLG2, DLG3, DUSP1, DUSP5, DUSP7, DUSP9, ENSA, EYA4, EYA2, G6PC, HPN, INPP1, INPPL1, OCRL, PFKFB4, PGAM1, PPM1B, PPP1CA, PPP1R3C, PPP2CB, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PPP4C, PPP5C, PPP6C, PSPH, PTEN, PTPN2, PTPN3, PTPN4, PTPN6, PTPN7, PTPN9, PTPN12, PTPN14, PTPRA, PTPRE, PTPRH, PTPRJ, PTPRN, PTPRN2, PTPRR, PTPRS, PTPRZ1, SBF1, SET, STYX, HSP90B1, TSC1, PTP4A1, AKAP1, DUSP11, PPM1D, CDC14B, INPP4B, IQGAP1, SYNJ1, CTDP1, BAG4, MINPP1, PPM1F, PPIP5K1, DLGAP5, SFI1, DNAJC6, SMG7, NUAK1, PTPRU, CTDSP2, FARP1, CTDSPL |
1751 | GO:0030030 | 0.00 | 1.55 | 191.26 | 250 | 662 | cell projection organization | ABL1, ACTB, ADAM10, ADCY1, AP2B1, ANGPT1, APBB2, APP, ARAF, ARF4, RERE, ATP2B2, KLF5, TSPO, CACNA1A, CACNB1, CACNB2, CACNB4, CALM3, CAMK2A, CAMK2G, CAPG, CD72, CDC20, CDH1, CHN1, CHRNB2, AP2M1, AP2S1, CLU, CNP, COL2A1, COL4A3, COL4A5, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, CREB1, CSF1R, CSF2, CSF2RB, CSNK1D, CSNK2A1, CSNK2A2, CTNNA1, CTNND2, DBN1, DHFR, DLG3, DLX5, DNM1, EPYC, DUSP5, DUSP7, DUSP9, E2F5, S1PR1, EFNA3, EFNA4, EFNB1, EFNB2, CELSR2, EGR2, EPHA2, EMP2, EMX1, CTTN, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, ETV1, ETV4, FGD1, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, GATA3, GDNF, GFRA1, GPC1, GRB2, GRID2, GRIN2A, ONECUT1, HPRT1, PRMT1, ICAM1, IL2RA, IL2RB, IL2RG, IL3, INPPL1, ITGA6, ISL1, ITGA1, ITGA5, ITGA9, ITGAV, JUN, KIF5A, MARK3, RAB8A, KITLG, NUBP1, NRCAM, NTF4, NTN3, OCRL, OPHN1, OTX2, PAX2, PCM1, PPP5C, PRKG1, MAPK1, MAPK3, PSPN, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTPRA, RAB3A, RAB5A, RAC3, RAF1, RAP2A, RASA2, RB1, RFX3, RFX4, RPGR, RPL24, RPS6KA1, RPS6KA2, RPS6KA3, RPS27A, RRAS, RXRA, RYK, SCN5A, SDC4, ITSN1, SHC1, SIAH2, STIL, SNAP25, SNX2, SOS2, SPTA1, SPTB, STRN, CNTN2, TBCE, DYNLT1, NR2E1, TOP2B, TRIO, TRPC1, TRPC3, TRPC4, TRPC5, TSC1, TULP1, TYROBP, UBB, UGT8, VCL, FZD3, FGF23, IFT88, USP9X, PICALM, CUL3, CNTNAP1, GAS7, KLF7, UNC5C, SSNA1, NUMB, DYNLL1, PEA15, IQGAP1, NRP2, AKAP4, PHOX2B, RPS6KA4, ATP6V0D1, DCLK1, VAPA, RPS6KA5, KLF4, SNAP29, KL, SLC9A3R1, NRXN3, PICK1, CHST3, ATG5, ONECUT2, PSMF1, BAG4, NRG2, SPAG6, FEZ2, CROCC, IFT140, KIAA0586, ARHGEF11, RBX1, RANBP9, PQBP1, ARPC5, ARPC1B, ACTR3, ACTR2, FRY, AKAP9, RASA4, FARP1, PSME3, PSMD14, ABCC4 |
1752 | GO:0051656 | 0.04 | 1.55 | 23.29 | 31 | 80 | establishment of organelle localization | BIRC5, ATP6AP1, BRCA2, CCNB1, CENPA, CENPE, CENPF, DYNC1H1, GEM, EIF6, LLGL2, MAP1B, NUMA1, OPA1, CHMP1A, PTK2, RAN, RB1, DYNLT1, UBB, YWHAZ, UXT, CDC23, ARHGEF2, ZW10, SLC9A3R1, CROCC, DLGAP5, ACTR3, ACTR2, SPRY1 |
1753 | GO:0051650 | 0.01 | 1.55 | 40.68 | 54 | 139 | establishment of vesicle localization | ACTN4, AMPH, ARCN1, ARF1, BBS4, CACNA1A, CANX, CD59, CDK5, COPA, COPB1, CSNK1D, DNM1, DNM2, GOLGA2, GRIA1, ITGA4, OPHN1, P2RX7, PFN2, SEPT5, PPP6C, RAB1A, RAB3A, RAB5A, RAB27A, RAP1A, TRAPPC2, ITSN1, SNAP25, SNCA, SYN1, SYT1, SYT5, AP3B2, CUL3, IKBKG, AP3B1, USO1, STX11, SNAP23, LIN7A, SYNJ1, AP3D1, RAB11B, COPB2, SNAP29, KIF3B, GOSR1, SEC22B, GOSR2, RIMS2, RIMS3, AP1M2 |
1754 | GO:0007126 | 0.04 | 1.54 | 23.41 | 31 | 80 | meiotic nuclear division | BRCA2, BRDT, CDC20, CDK2, ERCC4, GOLGA2, GPR3, ING2, MKI67, PPP2R1A, PRKAR1A, RAD21, RAD51, RAD51C, RAD51B, RAD51D, RPS6KA2, TOP2A, TOP2B, UBB, XRCC2, SMC1A, FKBP6, SMC3, ZW10, KIAA0196, REC8, SMC4, ACTR3, ACTR2, RAD50 |
1755 | GO:0043433 | 0.04 | 1.54 | 23.41 | 31 | 80 | negative regulation of sequence-specific DNA binding transcription factor activity | NR0B1, ANXA4, CAT, CEBPG, CMKLR1, FOXA2, ID1, ID2, IGF1R, IRAK1, IRAK2, SMAD7, MEN1, PIM1, PROX1, PTCH1, PTGIS, RB1, RNF2, XCL1, SFRP5, SP100, TRIM21, TNFSF4, SUMO1, WFS1, FZD6, NR0B2, TAX1BP1, KLF4, HAND1 |
1756 | GO:1902580 | 0.00 | 1.54 | 143.63 | 188 | 499 | single-organism cellular localization | ACTN4, ACTL6A, ALB, ARCN1, ATP2A1, BAD, BAX, BBS4, BCL2L1, BICD1, BNIP3L, BRCA2, BSG, TSPO, CACNB1, CASP8, CAV3, CCNB1, SCARB2, CD59, CENPE, AP2M1, CLTC, COPA, COPB1, CSNK1D, CSNK2A2, CTSK, DLG2, DLG3, DPP6, EPHA2, EMP2, ETV5, FAU, FCER1A, FGR, FLOT2, FNTA, KAT2A, GDI1, GFER, GLRB, GOLGA2, GOLGA4, GPR26, GRIA1, NRG1, HNMT, HSPA4, HSPA9, IL13, IL13RA2, INSIG1, ITGA4, ITGAL, ITGB1, EIF6, KIT, MAL, MAP1B, RAB8A, OPA1, PALM, CHMP1A, PDPK1, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PPP6C, PRKCI, PSMB7, PSMD8, PTCH1, PTEN, PTN, PEX19, PEX5, RAB1A, RAB6A, RAC1, RAC2, RAP2A, RB1, RNASE2, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, CLIP1, S100A13, TRAPPC2, SLC12A1, SORL1, SREBF1, SRP9, SRP14, SSR3, STXBP2, TNFRSF1A, TULP1, TULP2, TULP3, UBB, UBE2L3, SUMO1, UVRAG, VIL1, LAT2, WRB, YWHAH, YWHAZ, ZBTB17, FZD5, MADCAM1, BAP1, UXT, CUL3, OGT, BLZF1, RUVBL1, USO1, SSNA1, NUMB, DYNLL1, VAMP8, CDC23, CD84, CDKL2, RPL14, VAPB, VAPA, RAB11B, ITGB1BP1, COPB2, TRIP11, KIF3B, NRXN1, NRXN2, PEX16, PICK1, TMEM59, BAG4, SEC22B, GOSR2, RAPGEF2, ZFYVE16, ATG13, DLGAP5, SPCS2, TOMM20, GAB2, C2CD5, FAM20B, MFN2, BCL2L11, SAE1, ARFRP1, RAMP3 |
1757 | GO:0015758 | 0.03 | 1.53 | 27.22 | 36 | 93 | glucose transport | C3, EDNRA, G6PC, GPC3, FFAR3, NRG1, HK2, IGF1, INS, NUP98, PRKAA1, PRKCB, PRKCI, PTH, RANBP2, RAP1A, RPS6KB1, RTN2, SORT1, SLC2A2, SLC2A3, SLC2A4, SLC2A5, SLC5A2, STXBP3, HNF1A, TSC1, VIL1, NUP214, AAAS, CLTCL1, PIK3R3, PEA15, NUP155, NUP93, C2CD5 |
1758 | GO:0006461 | 0.00 | 1.53 | 164.10 | 214 | 569 | protein complex assembly | ABL1, ACACB, ACADS, ACAT1, ACVRL1, ADD1, AP2B1, ALAD, ANG, ANGPT1, ANXA5, ANXA6, APAF1, BIRC3, BIRC5, ARG1, ARHGAP6, ASL, ATP6V0A1, BAD, BBS4, BLK, CAMK2G, CAPG, CASQ1, CASQ2, CAT, CCNB1, CD3E, CD3G, ENTPD2, CD40, CD59, CD74, CDA, CENPE, CENPF, CHD4, CHRNB2, CHRNB4, AP2S1, CLU, COL1A1, COL6A1, COL6A2, COX15, CLDN3, CRYAB, CSNK1D, CTH, CTNNA1, CYBA, DARS, DDX3X, DHPS, DIAPH1, DIAPH2, DNM1, DPYSL3, EFNA5, EPRS, EPS15, FGA, GFAP, GJB1, GLRA1, GLRB, GOLGA2, GRIA1, HBA1, HBA2, HBE1, HCLS1, NRG1, HIP1, UBE2K, HMGCR, HMGA1, HPRT1, HRG, HSF4, HSPA4, IGF1R, IL1RAP, IL2RB, TNFRSF9, ILK, IMPDH2, INS, INSIG1, IRAK1, ITPR3, JUP, KCNA1, KCNA3, KCNA4, KCNA5, KCNC2, KCND2, KCND3, KCNJ2, KCNS1, KCNS2, KCNS3, KPNA3, IPO5, LIPC, SMAD1, SMAD3, SMAD6, NUP98, OAS1, OAT, OTX2, P2RX1, P2RX3, P2RX4, P2RX7, PAM, CHMP1A, PIK3C2A, PLN, PPID, PPP2R1A, PPP2R1B, PPP5C, PPP6C, PRKAA1, MAPK3, PSMD4, PSMD8, PSMD9, PSMD11, PTK2, PEX5, RAB1A, RAD51, RPS19, RRM1, RRM2, RXRA, RXRG, SCO1, TRAPPC2, SELP, SGK1, SH3BGR, SHMT1, SHMT2, SLC6A4, SLC9A1, SLC34A1, SLC22A1, SNAP25, SNCA, SNX2, SOD2, SORL1, SPTA1, SPTB, TRIM21, STXBP3, SYT1, TAF10, TAZ, TBCD, TP73, TRAF1, TSC1, TUBG1, UVRAG, VBP1, VDAC2, ZNF148, ZNF207, CLPP, PICALM, CUL3, OGT, IKBKAP, GAS7, USO1, TP63, TNKS, SNAP23, PEX11B, LIN7A, SYNJ1, CLDN1, LATS1, ZW10, REPS2, AURKB, ITGB1BP1, SNAP29, SLIT2, SLC9A3R1, KIF3B, ZFYVE9, NRXN1, GRHPR, EIF2AK3, SEC22B, GOSR2, PDE4DIP, NUP93, CEP57, KNTC1, TOMM20, SNAP91, KIAA0196, RANBP9, AKAP9, TRIM28 |
1759 | GO:0044089 | 0.03 | 1.53 | 28.74 | 38 | 99 | positive regulation of cellular component biogenesis | ATR, ADGRB2, BBS4, CLU, CTGF, LPAR1, EFNA5, EPHB1, EPHB2, EPHB3, HAS3, HRG, ID1, KDR, KIT, LIMK1, SMAD3, CNOT2, NTRK2, NTRK3, OXTR, P2RX7, PIP4K2A, PROX1, PTPRJ, SDC1, SDC4, SOX9, TPBG, TSC1, TSG101, NR1H2, WNT11, ITGB1BP1, NRXN3, NRXN1, PPM1F, PDCD6IP |
1760 | GO:0032502 | 0.00 | 1.53 | 75.49 | 101 | 321 | developmental process | ABCA1, ADCYAP1R1, ARHGDIB, ATP5G3, ATR, TNFRSF17, BLK, BRDT, BST2, CANX, TNFRSF8, CENPE, CHEK1, CLCN3, CLPS, CLTC, COMT, CRP, CYLC1, CYLC2, DAZ1, DDX1, EBF1, PHC2, ELF1, ELK1, ERCC6, ERF, ETV3, FLII, G6PC, GAS1, GNRH2, GNRHR, HIST1H1T, HIC1, HIP1, HIVEP2, HNRNPC, TNFRSF9, INSRR, IRAK1, ITPR1, KRT33B, DRG1, ODF1, PAEP, PCOLCE, PHB, PIM1, PTGDR, PTGS1, RPS3A, RPS4Y1, RPS11, SLC2A4, SNCA, SOD2, SPIB, SYP, TACR3, TNFRSF1B, TYK2, UBE2V1, UCP1, SCGB1A1, NR1H2, EIF4H, XPA, ZFX, ZNF3, ZNF7, ZNF45, ZNF74, PRDM2, PTP4A1, LTBP4, FKBP6, TNFRSF18, TNFRSF10D, TNFRSF10B, TNFRSF10A, PEX11A, CREG1, AP1M1, CDKL2, DDX21, AURKB, BCL7B, KIF3B, LITAF, NR1D1, PUM1, UTP14C, SPATA2, NUAK1, NR1I3, HDAC6, ARL4A, ZNF256, ALYREF |
1761 | GO:0043900 | 0.02 | 1.53 | 33.35 | 44 | 115 | regulation of multi-organism process | ACVR1B, AP2B1, ANXA5, BIRC3, ARF1, CD4, CD37, AP2M1, AP1S1, AP2S1, COX8A, CYBA, CD55, FGF7, FYN, GABRA5, B4GALT1, GLRA1, KCNQ1, NTHL1, PDK4, PEX13, PPP2R1A, PTAFR, RAC1, SCN1A, SNRPD1, SPINK1, STAT2, ZNF189, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, PDE5A, AP1M1, HIST1H3F, CHST3, NUP93, PUM1, PHYHIP, FGFBP1, AP1M2 |
1762 | GO:0017148 | 0.04 | 1.52 | 24.29 | 32 | 83 | negative regulation of translation | ADAR, ANG, ATF4, CIRBP, DAPK3, DDX3X, EIF4E, EIF4EBP2, EPRS, GAPDH, GRB7, EIF3E, IREB2, CAPRIN1, SMAD1, SMAD3, CNOT2, PURA, RAN, RARA, RBM4, UPF1, RPS3, SRP9, TARBP2, TSC1, PRKRA, EIF4EBP3, EIF2B3, EIF2AK3, PUM1, EIF4A3 |
1763 | GO:0031047 | 0.04 | 1.52 | 24.29 | 32 | 83 | gene silencing by RNA | ADAR, H3F3B, SMAD1, SMAD3, CNOT2, NUP98, RAN, RANBP2, RBM4, TARBP2, TSN, NUP214, AAAS, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, FKBP6, PRKRA, HIST1H3F, NUP155, NUP93, PUM1 |
1764 | GO:0051235 | 0.04 | 1.52 | 25.83 | 34 | 89 | maintenance of location | ABCA1, ACACB, ALB, ARL2, ATP2A1, BBS4, BCL3, TSPO, C3, CD4, CD36, SCARB1, CRP, DBN1, FBN1, GAA, GM2A, HEXB, HK2, IL10, ITGAV, JUP, TONSL, PTPN2, SORL1, SPAG4, STAT5B, TRIP6, NR1H2, UVRAG, NRIP1, DGAT1, TNFSF14, LATS1 |
1765 | GO:0051129 | 0.00 | 1.52 | 73.35 | 96 | 252 | negative regulation of cellular component organization | ACVRL1, ADD1, ARHGAP6, ATRX, BBS4, BCL2L1, BMP4, BUB1, BUB1B, TSPO, CAPG, CAV3, CCNB1, CCNF, CDC20, CDC27, CENPF, CHEK1, AP2M1, CLU, CLTC, CSNK2A1, CSNK2A2, ACE, DDX3X, DFFA, DNM2, DNMT1, DNMT3B, DPP4, DUSP1, S1PR1, ERCC4, FAP, FGFR3, GPX1, HGF, HMGA1, HNRNPC, DNAJB2, IGF1, INS, INSIG1, JARID2, MAD2L1, SMAD6, NUBP1, OPA1, PHF2, PRKAR1A, PRKD1, PTN, PEX5, RAC1, RAF1, RPS6KA2, SET, SETMAR, SGK1, SNCA, SORL1, SPTA1, SPTB, SYT4, TAF7, TBCD, TTK, UBE2D1, NR1H2, VDAC2, VIL1, XRCC5, ZNF207, PICALM, OGT, NUMB, TNKS, CDC23, CDC16, UNC119, ARHGEF2, ZW10, BUB3, AURKB, TRIP12, PICK1, ATG5, TMEM59, BAG4, GMFG, FEZ2, KDM4A, RUBCN, HDAC6, RAD50, WASF2 |
1766 | GO:0006469 | 0.02 | 1.52 | 36.58 | 48 | 125 | negative regulation of protein kinase activity | ABL1, ADAR, BMP4, CAV3, CDKN1A, CDKN2D, CHAD, DCN, DUSP1, DUSP5, DUSP7, DUSP9, GNAQ, GP1BA, HHEX, HMGCR, HSPB1, IGF1R, ILK, MEN1, PCP4, PDPK1, PPP2R1A, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, DNAJC3, PTEN, PTPN2, PTPN6, PTPRJ, RB1, SMPD1, SORL1, TAF7, TARBP2, NR2F2, TP73, CUL3, SOCS3, RGN, LATS1, ITGB1BP1, SOCS6, GMFG, PPM1F, SPRY1 |
1767 | GO:0031331 | 0.00 | 1.52 | 58.82 | 77 | 201 | positive regulation of cellular catabolic process | ADAM8, ADRA1B, APOH, ARNT, BAD, BAX, BNIP3L, ZFP36L2, CAV3, CCNB1, CDC20, CDC27, CLU, CSNK1D, DCN, PTK2B, GPLD1, DNAJB2, IFNG, IGF1, INS, KDR, SMAD7, P2RX7, PIP4K2A, PRKAA1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, RB1, UPF1, RPS27A, SKP1, SUMO3, SNCA, TRIM21, SUPV3L1, TNFRSF1B, UBB, UBE2D1, SUMO1, UVRAG, CUL3, CUL1, CDC23, CDC16, RGN, ATG5, PSMF1, TMEM59, GTPBP1, RNF14, DLGAP5, RNF40, PSME3, PSMD14 |
1768 | GO:0032270 | 0.01 | 1.51 | 41.76 | 55 | 150 | positive regulation of cellular protein metabolic process | AGTR1, APAF1, APP, BAD, BCL3, BOK, CASP8, CASP9, CD14, CD28, CDK4, CIRBP, COL4A3, CR1, CTSH, DAZ1, DDX3X, EIF5A, ELAVL1, F3, F12, FBLN1, HIP1, HPN, IFI16, KLKB1, P2RX1, PCOLCE, DNAJC3, PTAFR, RB1, REST, RPS6KB1, RPS6KB2, RXRA, S100A8, S100A9, TARBP2, CNTN2, CLEC3B, SUMO1, NR1H2, PICALM, TRADD, CRADD, TNFSF10, KLF4, EIF2AK3, RNF14, PPM1F, EIF4A3, DLGAP5, CASP8AP2, PDCD6, BCL2L11 |
1769 | GO:0042326 | 0.00 | 1.51 | 65.85 | 86 | 225 | negative regulation of phosphorylation | ABL1, ADAR, ANGPT1, ATF3, BAX, BDKRB1, BMP4, CALM3, CAV3, CCNB1, CDKN1A, CDKN2D, CHAD, CRYBA1, DCN, DUSP1, DUSP5, DUSP7, DUSP9, FBLN1, GNAQ, GP1BA, RAPGEF1, HHEX, HMGCR, FOXA2, HSPB1, IGF1, IGF1R, IGFBP3, ILK, INHA, JUN, SMAD3, SMAD6, SMAD7, MEN1, NTRK3, P2RX7, PCP4, PDPK1, PHB, PPP2R1A, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, DNAJC3, PRPSAP1, PTEN, PTPN2, PTPN6, PTPRJ, PTPRR, RANBP2, RB1, ATXN7, SMPD1, SNCA, SORL1, SPINK1, STAT3, TAF7, TARBP2, NR2F2, TP73, CUL3, OGT, DYNLL1, SOCS3, RGN, LATS1, ITGB1BP1, SOCS6, KLF4, SLIT2, SLC9A3R1, GMFG, PPM1F, RUBCN, RASSF2, RANBP9, CTDSP2, CTDSPL, SPRY1 |
1770 | GO:0007266 | 0.04 | 1.51 | 25.17 | 33 | 86 | Rho protein signal transduction | ABCA1, ABL2, AGTR1, ARHGAP4, ARHGAP5, ARHGAP6, ARHGDIB, ARHGDIG, BCR, CHUK, LPAR1, EDNRA, F2R, FGD1, ITGB1, LIMK1, PTH, RAC1, RAF1, ITSN1, SOS2, TRIO, VAV1, ARHGEF5, CUL3, CTNNAL1, ARHGEF7, ARHGEF1, ARHGEF2, GPR55, ARHGAP29, ARHGEF11, FARP1 |
1771 | GO:0007166 | 0.00 | 1.51 | 86.57 | 114 | 332 | cell surface receptor signaling pathway | ABCA1, ACPP, AES, ANXA1, ARNTL, ATP1A3, ADGRB2, BCL9, BSG, CCNE1, CD9, CD36, CD37, CD59, ADGRE5, CD151, CDA, COL1A1, COL4A3, CRH, CRHBP, CSNK1D, CSNK1G3, CSNK2A1, CSNK2A2, CTNND2, DDB1, EDNRB, CELSR2, EMD, ADGRE1, F2, GPC4, FZD2, GAS1, GCGR, GEM, GNAQ, GPR19, GRIA1, GRIA4, GRID1, GRM1, HIC1, PRMT1, IHH, ISL1, CD82, MGAT3, OXTR, P2RX1, P2RX3, P2RX5, P2RY2, P2RY4, P2RY6, PTCH1, PTH2R, RAB5A, RB1, PRPH2, RFX4, RYK, SALL1, TSPAN31, SCTR, SDC1, SEMA3F, SFRP5, STIL, SIX3, SLAMF1, SMARCA4, SOX4, SOX10, STRN, TACR2, CNTN2, TSPAN7, TULP3, UPK1B, KDM6A, VIPR2, TRPV1, WNT11, ZIC1, FZD5, SEMA3B, FZD3, FZD6, FZD7, FZD8, FZD9, DYRK2, RGS20, UNC5C, SSNA1, PTCH2, TNKS, LATS1, BCL7B, KLF4, GLP2R, SEMA3E, USP34, IFT140, KIAA0586, ZEB2, P2RY14, ZBTB33, FRAT1, HMGXB4, G3BP1, ATP6AP2 |
1772 | GO:0010563 | 0.00 | 1.51 | 81.36 | 106 | 278 | negative regulation of phosphorus metabolic process | ABL1, ADAR, ANGPT1, ATF3, BAX, BDKRB1, BMP4, TSPO, CALM3, CAV3, CCNB1, CDA, CDKN1A, CDKN2D, CHAD, CRY2, CRYBA1, DCN, DLG2, DLG3, DRD3, DUSP1, DUSP5, DUSP7, DUSP9, LPAR1, EDNRA, EDNRB, FBLN1, GALR1, GNAI3, GNAQ, GP1BA, RAPGEF1, HHEX, HMGCR, FOXA2, HPN, HSPB1, IGF1, IGF1R, IGFBP3, ILK, INHA, JUN, SMAD3, SMAD6, SMAD7, MEN1, NTRK3, P2RX7, PALM, PCP4, PDPK1, PHB, PPP2R1A, PPP5C, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, DNAJC3, PRPSAP1, PTEN, PTPN2, PTPN6, PTPRJ, PTPRR, RANBP2, RB1, ATXN7, SMPD1, SNCA, SORL1, SPINK1, STAT3, TAF7, TARBP2, NR2F2, TP73, AKAP1, CUL3, OGT, DYNLL1, IQGAP1, SOCS3, RGN, LATS1, ITGB1BP1, SOCS6, KLF4, SLIT2, SLC9A3R1, AKAP6, BAG4, GMFG, GABBR2, PPM1F, RUBCN, RASSF2, SFI1, RANBP9, CTDSP2, FARP1, CTDSPL, SPRY1 |
1773 | GO:0050714 | 0.05 | 1.51 | 23.65 | 31 | 81 | positive regulation of protein secretion | ABL1, ABL2, ADAM8, AGTR2, ALOX15B, ANG, APBB1, ARF1, CASP5, CD14, CD58, CSF1R, F2R, FGA, FGR, GATA3, IFNG, IGF1, IL1A, IL10, IL13, INS, KCNN4, P2RX7, PAEP, PPID, PRKCQ, SYK, TNFSF4, NR1H2, IL1RL1 |
1774 | GO:0008104 | 0.00 | 1.51 | 54.97 | 72 | 194 | protein localization | NR0B1, BIRC5, ARL1, ATR, ATRX, BICD1, BUB1B, CD4, CENPA, CSNK1D, CTNNA1, DBN1, DDX1, DDX3X, DIAPH1, DLG2, DLG3, DNMT3B, DPP6, EMP2, ERCC3, ETV5, FBN1, FGF7, FNTA, GAS8, GLRB, GNGT1, GRID2, GRIN2A, HHEX, ID1, ITGA4, ITGAL, KCNA1, KIF5A, SMAD7, MAL, ATXN3, NUBP1, NRCAM, YBX1, RAC1, RAD21, STIL, SLC9A2, SUMO3, SOX9, SPAG4, TNFAIP2, TULP1, TULP2, TULP3, UGT8, USP4, VCL, WNT11, IFT88, MADCAM1, CNTNAP1, NRP1, LATS1, AURKB, VAPA, NRXN2, AKAP7, RAPGEF2, CROCC, KLHL21, PIGK, PARP3, PTPRU |
1775 | GO:0051224 | 0.03 | 1.51 | 31.31 | 41 | 107 | negative regulation of protein transport | ANGPT1, ANXA1, ANXA4, ANXA5, BARD1, CD36, CDK5, DRD3, EMD, F2R, FBLN1, GDI1, GHSR, HMGCR, IFNA2, IL10, TNFRSF9, INS, KCNJ11, TONSL, PPM1B, PSMD9, RANGAP1, REST, CX3CL1, SFRP5, SOX4, SP100, SREBF1, TRIP6, TNFSF4, AKAP1, DYRK2, OGT, TNFSF14, ITGB1BP1, SLC9A3R1, CABP1, LITAF, BAG4, NR1H4 |
1776 | GO:0048666 | 0.00 | 1.51 | 58.01 | 76 | 207 | neuron development | ALK, ARF1, ARF4, BBS4, PRDM1, BMP4, TSPO, CDC20, CDH1, CLU, CNR1, CTF1, CTNNA1, DBN1, DHFR, LPAR1, EMX1, EN1, EPOR, PTK2B, EFEMP1, FZD2, GABRA5, GABRB2, GFAP, GNAT1, GNAT2, GNGT1, GPM6A, RAPGEF1, GRID2, HGF, PRMT1, IHH, JUN, NTF4, P2RY2, PALM, PCP4, SERPINF1, PPT1, PRKCI, PRKD1, PRKG1, PTN, RAP1A, RPGR, RXRA, SDC4, SNAP25, SOX3, SPOCK1, STRN, SYT1, SYT4, DYNLT1, TP73, TULP1, UGT8, VIM, WNT1, IFT88, SF3A2, GAS7, IQGAP1, CBFA2T2, VAPA, KLF4, CHST3, SLC4A7, BAG5, RIMS2, IFT140, KIAA0319, NR2E3, FRY |
1777 | GO:0032501 | 0.03 | 1.50 | 28.28 | 38 | 129 | multicellular organismal process | ACOX1, BRDT, CDC25C, HIST1H1A, HAS1, IL1R1, LIMK2, SMCP, OVGP1, PPP2R1A, PRKAG1, PSG2, PSG3, PSG5, PSG6, PSG9, PSG11, PZP, SBF1, SPAG4, SPAM1, SULT1E1, STYX, TAF4B, TBP, TRPM2, ZNF35, USP9Y, TPST2, FKBP6, DDO, RUVBL1, HERC2, FAM50A, TBPL1, SPAG6, CEP57, KIAA0196 |
1778 | GO:0031334 | 0.04 | 1.50 | 28.32 | 37 | 97 | positive regulation of protein complex assembly | ARF1, ARL2, BAX, BIK, CAV3, CD36, CSF2, CTTN, PTK2B, GRB2, ICAM1, PFN2, PRKCE, RAC1, RPS3, CLIP1, CCL21, FSCN1, TAL1, SUMO1, VEGFA, VIL1, WAS, ARHGEF5, HRK, PICK1, BAG4, GMFG, PIEZO1, HDAC6, BCL2L11, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, ABI2 |
1779 | GO:0034248 | 0.00 | 1.50 | 63.80 | 83 | 218 | regulation of cellular amide metabolic process | ADAR, ANG, APP, ATF4, BCL3, BPGM, CD28, CDK4, CIRBP, CLU, DAPK3, DAZ1, DDX1, DDX3X, DDX6, EIF2B1, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4EBP2, EIF4G2, EIF5, EIF5A, ELAVL1, EPRS, PTK2B, GAPDH, GRB7, HSPB1, IGF1, EIF3E, IREB2, ITGA2, CAPRIN1, SMAD1, SMAD3, CNOT2, PA2G4, PGAM1, PPP1CA, PRKAA1, MAPK1, MAPK3, DNAJC3, PTAFR, PURA, RAN, RARA, RBM4, UPF1, RPL38, RPS3, RPS6KA1, RPS6KA3, RPS6KB1, RPS6KB2, RXRA, S100A9, SORL1, SOX4, SRP9, TARBP2, TNFRSF1A, TSC1, EIF4H, PICALM, NSMAF, PRKRA, EIF4EBP3, EIF3F, EIF3G, EIF4G3, EIF2B3, EIF2B2, EIF2AK3, EIF5B, PUM1, EIF4A3, RBM8A, NR1H4, TRAP1, EIF1 |
1780 | GO:0070302 | 0.04 | 1.50 | 28.39 | 37 | 97 | regulation of stress-activated protein kinase signaling cascade | CAV3, CTGF, EPHA4, EPHB1, ERCC6, PTK2B, FCER1A, FLT4, HGF, HMGCR, PRMT1, IGF1R, IL1A, MEN1, MAP3K11, PRDX1, MAPK1, MAPK3, RAP2A, RPS3, CCL21, SLAMF1, SYK, TP73, TPD52L1, TRAF2, VEGFA, FZD5, ARHGEF5, FZD4, FZD7, FZD8, RIPK1, RIPK2, TRAF4, RASSF2, ZEB2 |
1781 | GO:0010638 | 0.00 | 1.49 | 64.73 | 84 | 222 | positive regulation of organelle organization | ACTL6A, ANXA1, BIRC5, ATR, ATRX, BAD, BAX, BBS4, BIK, CASP8, CD28, CSF2, CSNK2A2, CTSK, DCN, DKC1, DNMT1, DNMT3B, DRD3, FGF8, GCG, KAT2A, GPR26, HIST1H1B, NRG1, HNMT, IGF1, IGF1R, IGF2, IL1A, INS, ISL1, JARID2, KDR, CNOT2, OPA1, PIP4K2A, PRKD1, MAPK1, MAPK3, PSMB7, PSMD8, PTEN, RAC2, RB1, RNASE2, RPL28, SDC1, SFPQ, FSCN1, SREBF1, SURF4, SYT1, TAL1, TSG101, UBE2L3, VEGFA, YWHAH, YWHAZ, ZBTB17, FZD5, BAP1, CUL3, OGT, RUVBL1, DYNLL1, TNKS, EED, HRK, TNFSF10, RPS6KA4, CDKL2, AURKB, RPS6KA5, ATG5, ATG13, DLGAP5, RNF40, C2CD5, FAM20B, PDCD6IP, BCL2L11, SAE1, RAD50 |
1782 | GO:0006281 | 0.00 | 1.49 | 66.42 | 86 | 228 | DNA repair | ABL1, ACTL6A, APBB1, ATR, ATRX, BACH1, BARD1, BRCA2, CDK2, CEBPG, CHEK1, CSNK1D, DDX1, EP300, EYA4, ERCC3, ERCC4, EYA2, FANCE, FANCB, FANCF, FANCG, HMGN1, KPNA2, MEN1, MGMT, ATXN3, NUDT1, TONSL, PPP4C, PPP5C, RAD21, RAD23B, RAD51, RAD51C, RAD51B, RAD51D, RBBP8, UPF1, RPS3, SETMAR, SFPQ, SUMO3, SSRP1, TP73, SUMO1, UVRAG, XPA, XRCC2, XRCC5, YY1, CHAF1B, SMC1A, HIST1H4I, CDC45, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, COPS3, CDC14B, RUVBL1, ALKBH1, HERC2, RNF8, BAZ1B, SMC3, EXO1, COPS2, TRIP12, RECQL5, CHD1L, BRE, KDM4A, DCLRE1A, USP3, REC8, PARP3, RAD50, TRIM28, PSMD14 |
1783 | GO:0016482 | 0.00 | 1.49 | 132.25 | 170 | 460 | cytoplasmic transport | ADAR, ARCN1, ARF4, ARL1, ARNTL, RERE, BGLAP, TSPO, VPS51, CBLB, SCARB2, CD59, CD63, CDX2, AP1S1, CLTC, COPA, COPB1, CSE1L, CSNK1D, CD55, DYNC1H1, DNM2, EGR2, EIF4E, EIF5A, EMP2, EPS15, F7, F10, FAU, FGF9, FYB, GFER, GLE1, GOLGA2, GOLGA4, GOLGB1, GRIA1, HHEX, HSPA4, HSPA9, IFNG, INS, EIF6, JUN, KPNA2, KPNA3, KPNA4, NUP98, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PPP6C, PROC, PROS1, PEX19, PEX5, RAB1A, RAB5A, RAB5B, RAB6A, RAN, RANBP2, UPF1, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, SORT1, TRAPPC2, SET, SRSF1, SRSF5, SRSF7, SIX3, SNX2, SPTA1, SPTB, SRP9, SRP14, SSR3, STAT3, STYX, SYK, HSP90B1, TRPS1, TSC1, TSG101, UFD1L, NUP214, ANP32A, CLTCL1, EEA1, CUL3, AP3B1, BLZF1, USO1, AKR1C3, DYNLL1, SRSF9, PROZ, AP1M1, AP3D1, RPL14, SEC22C, ZW10, VAPB, VAPA, RAB11B, COPB2, TRIP11, RPL23, RAB9A, ZFYVE9, COG1, PEX16, GOSR1, SEC22B, VPS26A, GOSR2, NUP155, IPO13, NUP93, CEP57, USP6NL, ZFYVE16, SNX17, DHX38, SPCS2, TOMM20, RGP1, ZC3H11A, SMG7, SGSM2, MFN2, RBM8A, HMGXB4, ACTR2, ARFRP1, ALYREF, STX6 |
1784 | GO:0010506 | 0.03 | 1.49 | 33.95 | 44 | 116 | regulation of autophagy | ABL1, ABL2, ACTL6A, ATP6V0A1, BAD, BCL2L1, BNIP3L, TSPO, CSNK2A2, CTSK, DAPK3, DCN, CTTN, GATA4, KAT2A, GFAP, GOLGA2, HGF, IFI16, IFNG, KDR, KIF25, PIP4K2A, PRKAA1, RPL28, SNCA, SNRNP70, SREBF1, TRIM21, TSC1, UVRAG, VDAC1, ZBTB17, FZD5, IFT88, RUVBL1, RAB33A, ATG5, TMEM59, FEZ2, KDM4A, RUBCN, RB1CC1, HDAC6 |
1785 | GO:0002697 | 0.05 | 1.48 | 25.43 | 33 | 88 | regulation of immune effector process | AP2B1, ANXA5, BIRC3, ARF1, CD4, AP2M1, AP1S1, AP2S1, COX8A, FGF7, FYN, GABRA5, KCNQ1, NTHL1, PDK4, PEX13, RAC1, SCN1A, SNRPD1, STAT2, ZNF189, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, AP1M1, HIST1H3F, CHST3, NUP93, PHYHIP, FGFBP1, AP1M2 |
1786 | GO:0015749 | 0.04 | 1.48 | 27.80 | 36 | 95 | monosaccharide transport | C3, EDNRA, G6PC, GPC3, FFAR3, NRG1, HK2, IGF1, INS, NUP98, PRKAA1, PRKCB, PRKCI, PTH, RANBP2, RAP1A, RPS6KB1, RTN2, SORT1, SLC2A2, SLC2A3, SLC2A4, SLC2A5, SLC5A2, STXBP3, HNF1A, TSC1, VIL1, NUP214, AAAS, CLTCL1, PIK3R3, PEA15, NUP155, NUP93, C2CD5 |
1787 | GO:0044700 | 0.00 | 1.48 | 544.74 | 664 | 2106 | single organism signaling | ABCA1, ABCA4, ACTB, ACTL6A, ADAR, ADCYAP1R1, ADD1, ADRBK1, AES, APLNR, NR0B1, AHR, ANGPT2, ANXA4, ANXA6, APBB1, APBB2, BIRC5, APLP2, APP, KLK3, TRIM23, ARF4, ARF5, RND3, ARHGAP5, ARHGDIB, ARHGDIG, ARL1, ARR3, ASNS, ATF4, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATRX, AVPR1B, AVPR2, ADGRB2, BBS4, BCL2A1, BCL3, BCL9, TNFRSF17, OPN1SW, BCR, BDKRB1, BICD1, PRDM1, BMX, BNIP3L, BOK, DST, BRCA2, BSG, BTK, BUB1B, CAPN5, DAGLA, CAMLG, CAPS, CASP9, CAV3, RUNX2, CBLB, KRIT1, CCNC, CCNE1, CCNT2, CD3D, CD3G, CD5, CD6, CD7, CD9, TNFRSF8, SCARB1, CD37, ENTPD2, CD59, CD69, CD72, CD151, CDA, CDC25C, CDH1, CDH6, CDK2, CDK4, CDK6, CDK8, CDKN1A, CDKN2D, CENPA, CENPE, CENPF, CHAD, AKR1C4, CHKA, CLCN6, TPP1, CLPS, CCR3, CCR8, CMKLR1, CNGA1, COL2A1, COL4A3, COL15A1, CLDN3, CR1, CR2, CRY2, CRYAB, CRYBA1, CSH1, CSNK1G3, CSNK2A2, CTLA4, CTNND1, CTSK, CTSS, CD55, DGKB, DCC, DDB1, DDX3X, DDX11, DIAPH1, DIAPH2, DMBT1, DNM2, DOK1, RCAN1, DTX1, DUSP1, E2F5, EDNRB, CELSR2, EPHA2, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4G2, ELF1, ELK1, ELK3, EMD, ADGRE1, CTTN, EP300, EPHA3, EPHB1, EPHB2, EPHB3, EPS15, ERG, ESRRG, ETV2, EXT2, EXTL3, EYA2, F2RL2, FBLN1, FBN1, EFEMP1, FCER2, FCGR2A, FCGR2B, FCGRT, GPC4, FGD1, GPC5, FLT3LG, FPR2, FPR3, FSHB, CENPI, NR5A2, FUT8, ACKR1, FYB, IFI6, GABRE, GAS1, GCGR, OPN1MW, GDI1, GDI2, GEM, GFRA1, B4GALT1, GH2, GMDS, GNA15, GNAQ, GNAT1, GNAT2, GNRH2, GNRHR, GP1BA, GPC1, GPR3, GPR4, XCR1, GPR15, GPR17, GPR19, LPAR4, GPR25, GPR26, GRID1, GRINA, CXCL2, CXCL3, GRPR, GTF2I, GUCA1A, GUCY2C, GUCY2F, GUCY2D, H3F3B, HDGF, HIP1, HIVEP2, NR4A1, HNF4G, ONECUT1, HPGD, HRG, HSPB1, ICAM2, ID1, IFI16, SP110, IFIT1, IFIT3, IFNA5, IFNA13, IFNA17, IFNA21, IFNGR1, IFNW1, IGF2R, IGFBP6, IL1R1, IL1RAP, IL10RA, IL11RA, IL12RB2, IL13RA2, IL15RA, TNFRSF9, INCENP, INPP1, INSIG1, INSRR, ITGA6, IRF1, IRF5, ISG20, ITGA4, ITGA7, ITGA9, ITGAD, ITGAE, ITGAM, ITGAV, ITGB5, JUNB, CD82, KLK2, KLRC3, KPNA1, KPNA2, KPNA3, KPNA4, LIMK1, LLGL2, LRPAP1, LSP1, LTBP2, MAD2L1, SMAD1, SMAD6, SMAD7, SMAD9, SCGB2A1, MGAT3, CIITA, FOXO4, PPP1R12A, PPP1R12B, CNOT2, YBX1, DDR2, NUP98, OAS1, OAS3, OCRL, OPA1, OR1F1, OR2C1, OTX2, P2RY2, P2RY4, P2RY6, PRDX1, SERPINE1, PALM, PAX2, PDE4B, PDE8A, PDK4, PENK, PF4V1, PIK3C2A, PIK3C2B, PIM1, PI4KA, PPM1B, PPP2CB, PPP2R5D, PPP4C, PRCP, PRKAB2, PRKAG1, PRKCI, PRKCSH, PRKG1, DNAJC3, PTAFR, PTCH1, PTGDR, PTGER1, PTGER2, PTH2R, PTPRE, PTPRR, RAB4A, RAB5B, RAB6A, RAB27A, RABIF, RAC2, RALA, RAN, RANBP1, RANBP2, RANGAP1, RAP1GAP, RAP2A, RAP2B, RARB, RB1, RBM4, RBP1, RBP2, OPN1LW, RCVRN, PRPH2, DPF2, RFX4, RGR, RGS1, RGS10, RGS12, RGS13, RIT1, RLBP1, RNF6, RPS6, RPS6KB1, RPS6KB2, RPS19, RPS27, CLIP1, RSU1, RXRA, RXRG, S100A1, SORT1, S100A11, TSPAN31, ATXN7, SCTR, SDC1, SDC4, SEC14L1, SELE, SEMA3F, SFRP5, SGK1, SIAH2, STIL, SIPA1, SIX3, SKP1, SMARCC1, SMPD1, SNAI1, SOD2, SORL1, SOX10, SP1, SP100, SPARC, SPINK1, SPOCK1, SRPK2, TRIM21, STAT2, STAT4, STAT5B, STAT6, STK10, STRN, STYX, SULT1A3, T, TACR3, TAF7, TBL1X, DYNLT1, NR2F1, NR2F2, TSPAN7, TPT1, NR2C2, HSP90B1, TRAF1, TRHR, TRIO, TRPC3, TSC1, TSG101, TUFT1, TULP3, TNFSF4, TYK2, TYRO3, TYROBP, UBA7, UBE2D1, UBE2D2, SUMO1, UPK1B, SCGB1A1, NR1H2, KDM6A, VAV1, VDAC2, VDR, VIL1, VIM, TRPV1, WAS, LAT2, WFS1, XPA, ZIC1, ZBTB17, ZNF217, IL1R2, SCG2, FZD3, NUP214, AAAS, ANP32A, RND2, MADCAM1, NRIP1, CLTCL1, USP9X, SMC1A, USP9Y, ARID1A, HIST1H4I, FZD6, FZD9, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, OR1A1, OR1D5, OR1G1, OR3A3, SPARCL1, BCAR3, NSMAF, DYRK2, CUL4A, CUL2, CUL1, SORBS2, OGT, PIK3R3, IKBKAP, DGKE, COPS3, RGS20, UNC5C, SSNA1, OASL, PTCH2, CHRD, NUMB, EIF4G3, S1PR4, CTNNAL1, TNFSF13, ADAM15, RGS9, DLK1, TNFRSF10D, PEX11B, PEX11A, IL1RL2, INPP4B, NRP2, AKAP4, VNN1, SGPL1, TAX1BP1, HIST1H3F, RPS6KA4, ATP6V0E1, PGLYRP1, CDKL2, SOCS3, BAZ1B, TAAR5, UBA3, DOK2, PSTPIP1, ANGPTL1, DIRAS3, USP8, RGN, LATS1, ATP6V0D1, SMC3, ARHGEF1, IL1RL1, ARHGEF2, RASSF9, ZW10, BUB3, REPS2, DCLK1, AURKB, XPR1, VAPB, RPS6KA5, STK17B, STK17A, CYTH2, BCL7B, TAAR2, SOCS6, KLF4, COPS2, TRIP10, TRIP4, GLP2R, SLIT2, RAB33A, RAB9A, ZFYVE9, ARHGAP29, AKAP7, IL27RA, ONECUT2, BAG5, BAG3, ATP6V1G1, BCAR1, GTPBP1, GOSR2, BRE, CDC42BPB, RNF14, RAB36, AATK, GUCA1C, GNA14, FEZ2, PPM1F, RALGPS1, ZNF516, SDC3, PHF14, NUP93, CEP57, ADAMTSL2, SEMA3E, KNTC1, IFT140, ARHGAP32, ZNF536, SLK, ZFYVE16, SNX17, KIAA0586, CKAP5, TATDN2, SPOCK2, KIAA0141, CUL7, RB1CC1, ARHGEF11, GAB2, C2CD5, TRIL, RHOBTB1, NUAK1, DENND4B, MFN2, P2RY14, ARHGAP25, OXSR1, NR1I3, NR1D2, CASP8AP2, NR2E3, ZBTB33, TANK, PDCD6, HMGXB4, RANBP9, IL18BP, PTPRU, COL4A3BP, ARPC5, ARPC1B, ACTR3, ACTR2, CTDSP2, ARPC2, SGK2, FEM1B, ARL4A, TRAP1, ARFRP1, G3BP1, ABI2, FARP1, WASF2, RNF41, RCAN2, RASGRP2, SPRY1, STAM2 |
1788 | GO:1903829 | 0.01 | 1.48 | 57.36 | 74 | 196 | positive regulation of cellular protein localization | ACTL6A, BAD, BMP4, BMPR1A, CASP8, CCNB1, CDH1, CDK5, CHRM1, CSNK2A2, CTSK, DKC1, EDA, EPHA2, EMD, FYN, KAT2A, GPR26, HCLS1, NRG1, HNMT, IFNG, IGF1, IL12B, IL18, INS, ITGB1, JUP, KPNA1, IPO5, SMAD3, OAZ1, OAZ2, PCM1, PDPK1, PRKCI, PRKCQ, PSMB7, PSMD8, PTGS2, PTN, RAC2, RNASE2, RPL28, SLC9A1, SORL1, TRIP6, UBE2L3, VEGFA, VIL1, YWHAH, YWHAZ, ZIC1, ZBTB17, FZD5, BAP1, OGT, RUVBL1, DYNLL1, TNFSF14, IL18R1, CDKL2, ITGB1BP1, NRXN1, EIF2AK3, AKAP6, ATG13, C2CD5, FAM20B, BCL2L11, SAE1, TRIM28, NUTF2, RAMP3 |
1789 | GO:0043043 | 0.00 | 1.48 | 101.26 | 130 | 346 | peptide biosynthetic process | ANG, SLC25A4, APP, ATF4, BCL3, SLC25A20, CD28, CDK4, CIRBP, SLC25A10, DAPK3, DARS, DAZ1, DDX1, DDX3X, DDX6, DHPS, EEF1B2, EIF1AX, EIF2B1, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4EBP2, EIF4G2, EIF5, EIF5A, ELAVL1, EPRS, PTK2B, FAU, GAPDH, GARS, GGT7, GRB7, GSS, HARS, HSPB1, IGF1, EIF3E, IREB2, ITGA2, EIF6, CAPRIN1, CNOT2, PA2G4, PCSK5, PPP1CA, MAPK1, MAPK3, DNAJC3, PTAFR, PURA, QARS, RARA, RBM4, UPF1, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL36AL, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS6KA1, RPS6KA3, RPS6KB1, RPS6KB2, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, RXRA, S100A9, SOX4, SOX11, SRP9, SRP14, SSR3, TARBP2, TSC1, TUFM, UCP1, EIF4H, AIMP2, SLC25A16, SLC25A12, EIF4EBP3, DDX3Y, EIF3F, EIF3G, EIF4G3, EIF2B3, EIF2B2, EIF2S2, SLC25A14, RPL14, RPL23, EIF2AK3, GTPBP1, EIF5B, PUM1, EIF4A3, SPCS2, RBM8A, TRAP1, SLC25A13, SLC25A15, EIF1 |
1790 | GO:0022604 | 0.00 | 1.47 | 81.07 | 104 | 277 | regulation of cell morphogenesis | ABL1, ACTN4, ANXA1, ARHGAP4, BBS4, BMPR2, CACNA1A, CDK5, CHN1, CHRNB2, COL1A1, CSF1R, DAPK3, DCC, COCH, DIAPH1, DNM2, LPAR1, EFNA1, EFNA5, CTTN, EPHA3, EPHA4, EPHB3, F2, PTK2B, FBLN1, FGA, FGD1, FGR, FYN, GAS2, GDI1, GDNF, GOLGA4, HAS2, HEXB, NRG1, FOXA2, HPN, ICAM1, ID1, ILK, ITGA7, KDR, KIT, LIMK1, CAPRIN1, SMAD3, SMAD7, MAP1B, NRCAM, NTRK2, NTRK3, PALM, PAX2, PTEN, PTK2, PTN, PTPRZ1, RAC1, RAC3, RAP2A, RET, RNF6, S100A13, SALL1, SEMA3F, SGK1, SNAI1, SPARC, SPTA1, SRF, SYT1, SYT4, CNTN2, NR2E1, TNR, TTC3, VEGFA, VIL1, YWHAH, LRP8, SEMA3B, IFT88, RND2, SEMA7A, GAS7, NRP1, ARHGEF7, ARHGEF1, ZMYM6, ITGB1BP1, SLIT2, SLC9A3R1, ATG5, AATK, RAPGEF2, RIMS2, SEMA3E, IFT140, CUL7, PQBP1, ARPC2 |
1791 | GO:0051495 | 0.03 | 1.47 | 33.36 | 43 | 114 | positive regulation of cytoskeleton organization | ARF1, ARL2, CAV3, CCNB1, CDK5, CTGF, LPAR1, CTTN, PTK2B, GRB2, HCLS1, ICAM1, ID1, LIMK1, SMAD3, NTRK3, P2RX7, PFDN2, PFN2, PRKCE, PRKCQ, PROX1, RAC1, RPS3, CLIP1, CCL21, SDC4, VIL1, WAS, WNT11, ARHGEF5, ITGB1BP1, PICK1, BAG4, GMFG, PPM1F, WDR1, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, ABI2 |
1792 | GO:0051607 | 0.01 | 1.47 | 55.31 | 71 | 189 | defense response to virus | ADAR, AP2B1, ANXA5, BIRC3, ARF1, BNIP3L, BST2, CD4, CD8A, CD28, CD86, CD37, CD40, AP2M1, AP1S1, AP2S1, COX8A, CXADR, DMBT1, FGF7, FYN, GABRA5, IFI16, IFIT1, IFIT3, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IL2RA, IL12B, IRF1, IRF5, ISG20, KCNJ8, KCNQ1, NTHL1, OAS1, OAS3, PCBP2, PDK4, PEX13, PPM1B, DNAJC3, RAC1, SCN1A, SEC14L1, SNRPD1, STAT2, TARBP2, TRIM25, ZNF189, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, FCN3, OASL, AP1M1, HIST1H3F, CHST3, NUP93, PUM1, PHYHIP, FGFBP1, AP1M2, ABCC9 |
1793 | GO:0006725 | 0.00 | 1.46 | 919.53 | 1085 | 3142 | cellular aromatic compound metabolic process | ABAT, ABCA1, ABCA2, ABL1, ACACB, ACPP, ACTN4, ACTL6A, ACTN1, ACVR1B, ACVR2B, ACVRL1, ADA, ADAM8, ADAR, ADCY1, ADCY7, ADCYAP1R1, ADSS, AEBP1, AES, AGTR2, NR0B1, AHCY, AHR, AK1, AK2, ALAD, ALAS2, ALDOC, ALK, ALX3, AMPD1, AMPD2, ANG, ANPEP, ANXA1, ANXA3, ANXA4, APAF1, APBB1, APBB2, XIAP, BIRC5, APP, APRT, AQP1, ARF4, PHOX2A, ARNT, ARNTL, ASCL1, ASCL2, ASIP, ATF3, ATF4, RERE, ATP1A2, ATP2B2, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V0A1, ATR, ATRX, AVPR2, BACH1, BAD, BARD1, BAX, BCHE, BCL3, BCL9, BICD1, PRDM1, BLVRA, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, BPGM, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTK, BYSL, TSPO, CACNB4, CALM3, CAMK2A, CAT, RUNX2, CBL, CCNB1, CCNC, CCNE1, CCNT2, CD3D, CD28, CD86, TNFSF8, CD36, ENTPD2, CD40, CDA, CDK11B, CDC6, CDC25A, CDC25C, CDH1, CDK2, CDK5, CDK8, CDKN1A, CDKN2D, CDX2, CEBPE, CEBPG, CENPB, CENPF, CHD2, CHD4, CHEK1, CHRNB2, CHUK, CLU, CLK1, CLK3, CLNS1A, CMKLR1, CNP, COL1A1, COMT, COX6A1, COX6B1, COX7B, COX7C, COX8A, COX15, CPOX, CPS1, CREB1, CRH, CRX, CRY2, CSF2, CSNK1D, CSNK2A1, CSNK2A2, CSTF3, CTGF, CTH, CTNS, CTNND1, CTNND2, CTRB1, CYP1A2, CYP2A6, CYP2F1, DAO, DAPK3, DARS, DBH, DBP, DCN, DCT, DDB1, DDX1, DDX3X, DDX5, DDX6, DHX8, DDX10, DDX11, DFFA, DFFB, DHFR, DHODH, DIO1, DKC1, DLD, DLG2, DLG3, DLX5, SARDH, DNASE1, DNASE1L1, DNASE1L2, DNASE1L3, DNM2, DNMT1, TRDMT1, DNMT3A, DNMT3B, DNTT, DRD3, DRD5, ARID3A, ATN1, RCAN1, TSC22D3, DTX1, DUSP1, E2F5, E2F6, E4F1, EBF1, TYMP, ECM1, EDA, S1PR1, LPAR1, EDNRA, EDNRB, EFNA1, CELSR2, EGR2, EGR3, EGR4, EIF4A1, EIF4A2, EIF4B, EIF4E, ELAVL2, ELF1, ELF3, ELK1, ELK3, EMX1, EMX2, EN1, ENO2, SLC29A1, EP300, EPHA5, EPRS, EYA4, ERCC3, ERCC4, ERCC6, ERF, ERG, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA2, EZH1, F2R, FANCE, PTK2B, FANCB, FANCF, FANCG, FAU, FBN1, EFEMP1, FEN1, FGF4, FGF7, FGF8, FGF9, FGFR3, FOXD1, FLII, AFF2, FSHB, FSHR, NR5A2, FUT8, FZD2, G6PC, GALR1, GAPDH, GARS, GATA3, GATA4, GATA6, GCG, KAT2A, GDF9, GDNF, GHRHR, GIF, GPC3, GLO1, GMDS, GNAI3, GNAS, GOT2, GPI, GPX1, GPX2, GRIN2A, GSC2, GSTZ1, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GUK1, GUCY2D, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, H3F3B, HARS, HAS3, HBE1, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIP1, HIVEP2, HK2, HLF, HMBS, HMGN1, HMGCR, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HNMT, HNRNPC, HOXC10, HOXC11, HOXD4, HOXD8, HOXD9, HOXD10, HOXD12, HPD, HPN, HPRT1, HPX, PRMT1, HSBP1, HSF4, HTR2C, ICAM1, ID1, ID2, IDH1, IFI16, SP110, IFNA2, IFNG, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL3, IL10, ILK, IMPDH1, IMPDH2, IDO1, ING2, INS, INSIG1, EIF3E, IRAK1, ITGA6, IRAK2, IRF1, IRF5, ISG20, ISL1, JARID2, JUN, JUNB, JUND, JUP, KCNK2, KCNQ1, KIT, KPNA1, KPNA2, LDHC, LMO1, LTF, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MDH2, MEN1, MEOX2, KITLG, MGMT, CIITA, ATXN3, MKI67, AFF1, FOXO4, NUDT1, PPP1R12A, DRG1, TONSL, CNOT2, CNOT4, NRF1, YBX1, NTHL1, NTRK2, NTRK3, DDR2, NUP98, NVL, OAS1, OAS3, OGDH, ORC1, ORC2, ORC4, OTX1, OTX2, OVOL1, P2RX7, P2RY11, PA2G4, PRDX1, PAH, SERPINE1, PALM, PAM, PAX2, PAX3, PAX9, PCBP2, PCK1, PCNA, CHMP1A, PDE4B, PDE8A, PDPK1, PEG3, PFAS, PFKFB4, PGAM1, PGD, PGK2, PGR, PHB, PHF2, PIM1, EXOSC9, PPID, PPP1R8, PPP2R1A, PPP2R2A, PPP2R5D, PPP4C, PPP5C, PRIM2, PRKAA1, PRKAB2, PRKAG1, PRKAR1A, PRKCB, PRKCI, PRKD1, PRKCQ, MAPK1, MAPK3, PROX1, PRPS2, PRPSAP1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD9, PTAFR, PTCH1, PTEN, PTGDR, PTGIS, PTH, PTGS2, PTMA, PTMS, PTPN14, PURA, PURB, ABCD4, QARS, QDPR, RAC1, RAD21, RAD23B, RAD51, RAD51C, RAD51B, RAD51D, RAF1, RAG1, RAG2, RAN, RANBP2, RARA, RARB, RB1, RBBP4, RBBP6, RBBP8, RBL2, RBM4, RBMS1, RBMS2, RCVRN, UPF1, DPF2, REST, RET, REV3L, RFC1, RFC3, RFC4, RFC5, RFX1, RFX3, RFX4, RFXAP, RGS12, RHEB, RLF, RNASE1, RNASE2, RNASE3, RNASE6, RNF2, RNF6, RP9, RPA2, RPA3, RPE, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS6KA1, RPS6KA3, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, RRM1, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A11, S100A12, SALL1, SATB1, ATXN7, XCL1, SDHC, TRAPPC2, SET, SETMAR, SFPQ, SFRP5, SRSF1, SRSF5, SRSF7, SFSWAP, TRA2B, SGK1, SHC1, SHMT1, SHMT2, SIAH2, SIM2, SIX3, SLC9A1, SLC34A1, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCD3, SMARCE1, SUMO3, SNAI1, SNAPC3, SNCB, SNAPC4, SNCA, SNRNP70, SNRPA, SNRPA1, SNRPC, SNRPD1, SNRPE, SNRPF, SOD2, SOX3, SOX4, SOX5, SOX9, SOX10, SOX11, SP1, SP2, SP3, SP100, UAP1, SPIB, SPTA1, SPTB, SQLE, SRD5A1, SREBF1, SRF, SRPK2, SRY, TRIM21, SSRP1, STAT2, STAT3, STAT4, STAT5B, STAT6, SULT1E1, SULT1A3, SULT1C2, SULT2B1, SUPV3L1, SYK, T, TACR3, TAF4B, TAF7, TAF10, TAL1, TARBP1, TARBP2, TAT, TAZ, TBL1X, TBP, HNF1A, GCFC2, ZNF354A, PRDX2, NR2F1, NR2F2, KLF10, NR2E1, TMPO, TNFRSF1A, TNNI2, TOP1, TOP2A, TOP2B, TP73, TPMT, NR2C1, NR2C2, TRAF1, TRAF2, TRH, TRIP6, TRPC1, TRPS1, TSN, TSC1, TSG101, TTF1, TULP3, TNFSF4, TYMS, TYR, UBB, UBA7, UBE2D1, UBE2D2, UBE2L3, UBE2V1, UBE3A, SUMO1, UCP1, UFD1L, SCGB1A1, UNG, USP4, NR1H2, UPP1, UQCRC1, UQCRC2, UQCRH, UROS, USF1, UVRAG, VAV1, VDR, VEGFA, VIP, VIPR2, WFS1, WNT1, WNT11, WRN, XPA, XRCC2, XRCC5, YY1, YWHAH, YWHAZ, ZFP37, ZFPL1, ZFX, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF33B, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF221, ZNF91, ZNF99, ZNF124, ZNF131, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF208, ZNF214, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZP3, ZXDA, PRDM2, LRP8, FZD5, AIMP2, MAFK, ARHGEF5, NUP214, PDHX, FOSL1, FGF23, AAAS, CDK2AP1, ANP32A, SF3A2, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, RBM10, KDM5C, SMC1A, USP9Y, ARID1A, HIST1H4I, PICALM, CDC45, EOMES, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NR0B2, UTF1, DUSP11, CUL4A, CUL3, CUL2, TTF2, KLF11, SMARCA5, FKBP6, OGT, PARG, KCNAB2, IKBKG, IKBKAP, HAT1, GAS7, COPS3, PIR, FCN3, BLZF1, CDC14B, PRPF18, RRP1, KHSRP, PRKRA, STK16, RGS20, RUVBL1, KLF7, TP63, RNASET2, CHRD, DDX3Y, PDE5A, DYNLL1, TNKS, SRSF9, TRADD, EED, RIPK1, TNFSF13, RIPK2, SUCLG1, CREG1, SAP30, HESX1, ALKBH1, PER3, TAX1BP1, BUD31, HERC2, PHOX2B, MBD4, FUBP3, KYNU, HIST1H3F, HIST1H2AG, RPS6KA4, TNFSF18, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, RPL14, PAPSS1, DIRAS3, USP2, RGN, PDLIM1, SMC3, PRPF3, CBFA2T2, DYRK1B, CTDP1, EXO1, SCAF11, ARHGEF2, DDX21, BMP15, AURKB, VAPB, CCPG1, RPS6KA5, ITGB1BP1, ZNF235, KLF4, COPS2, TRIP12, TRIP11, HMGN3, TRIP4, GTF3C5, GTF3C4, GTF3C3, EFTUD2, RPL23, COX5A, RECQL5, ZRANB2, SNRNP40, DDX23, HAND1, ZNF264, EIF2AK3, FHL5, PICK1, IL27RA, AKAP6, ATG5, ONECUT2, LITAF, TBPL1, ZNF254, TP53I3, CIR1, CHD1L, GTPBP1, GABBR2, NR1D1, CLOCK, BRE, SOX13, ENTPD4, RBM39, CREB5, AKAP12, RNF14, GUCA1C, SNCAIP, NUP155, PPM1F, ZNF516, SAFB2, PHF14, KDM4A, VGLL4, NUP93, BZW1, KIAA0391, RAPGEF2, DHX34, ST18, UTP14C, ZNF646, VPRBP, USP34, SETD1A, ZNF536, ZFYVE16, EIF4A3, DHX38, TATDN2, RNF40, RB1CC1, ARHGEF11, GINS1, ZEB2, ZBTB24, ZNF518A, SMG7, RNF10, ZBTB5, DCLRE1A, RBM8A, USP3, NR1I3, NR1H4, NR1D2, RBX1, REC8, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, GNE, PARP3, ABCB6, PDCD7, PQBP1, RAD50, ZNF263, YAF2, G3BP1, SUGP2, TRIM28, SLC25A13, ZNF197, ZNF256, ALYREF, RNF41, PSMD14, OLIG2, DENND4A, IRX5, RAMP3 |
1794 | GO:0061025 | 0.05 | 1.46 | 27.22 | 35 | 93 | membrane fusion | ANXA1, BAX, BCL2A1, CD9, GNAI3, RAB8A, OPA1, SERPINA5, RAB3A, RABIF, SLAMF1, SNAP25, SPAM1, SYT1, SYT4, TSG101, UVRAG, DYSF, EEA1, TPST2, USO1, VAMP8, STX11, SNAP23, SEC22C, RABEP1, VAPA, SNAP29, GOSR1, SEC22B, GOSR2, RUBCN, C2CD5, MFN2, STX6 |
1795 | GO:0071704 | 0.00 | 1.46 | 904.11 | 1028 | 3397 | organic substance metabolic process | ABCA2, ABCA3, ABCA4, ABL1, ABL2, ACP1, ACP2, ACTA2, ACTB, ACTG2, ACTN4, ACTL6A, ACTN1, ACVR1B, ACVR2B, ACVRL1, ADAM10, ADAR, ADD1, ADPRH, ADRBK1, AES, AGTR1, NR0B1, AHR, ALK, ALX3, ANXA3, ANXA4, APOF, APBB1, APBB2, BIRC3, XIAP, BIRC5, APLP2, KLK3, TRIM23, PHOX2A, ARR3, ASCL1, ASCL2, ASIP, RERE, ATP1A1, ATP6AP1, ATR, ATRX, AXL, BACH1, BBS4, BCL9, OPN1SW, BCR, BDKRB1, BICD1, PRDM1, BLK, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMX, BOK, BRCA2, BRDT, BST2, KLF9, KLF5, BTF3, BTK, BYSL, CAPN5, C7, CAMK2A, CAMK2G, CAMLG, CAPN6, CASP5, CASP9, CASP10, RUNX2, CCNC, CCNE1, CCNT2, CD3D, CD3E, CD4, CD9, CD14, CD86, TNFRSF8, TNFSF8, CD36, CD40, CD63, CDK11B, CDC6, CDC25A, CDC25C, CDH1, CDK3, CDK6, CDK8, CDKN1A, CDKN2D, CDX2, CEBPE, CEBPG, CENPB, CENPE, CHAD, CHD2, CHD4, CHEK1, CHRM1, CHRM3, CHUK, TBCB, CKS1B, CLCA1, CLK1, CLK3, CLNS1A, CCR1, CMKLR1, COL1A1, COL4A3, COL4A5, COL4A6, COL6A1, COL6A2, COL6A3, COL9A1, COL9A2, COL9A3, COL10A1, COL15A1, COL19A1, COX6A1, COX6B1, COX7B, COX7C, CPA1, CR1, CR2, CREB1, CRKL, CRP, CRX, CRY2, CRYAB, CRYBA1, CSF2, CSF2RB, CSNK1G3, CST1, CST6, CSTF3, CTF1, CTGF, CTNND1, CTNND2, DBP, DDX5, DHX8, DDX10, DDX11, DHCR7, DKC1, DLX5, DMBT1, DNM1, DNM2, TRDMT1, DNTT, DPH2, DPP4, DPP6, ARID3A, ATN1, RCAN1, TSC22D3, DTX1, DUSP5, DUSP7, DUSP9, E2F5, E2F6, E4F1, EBF1, ECM1, EDA, S1PR1, PHC2, EFNA1, EFNA5, CELSR2, EGR2, EGR3, EGR4, EPHA2, SERPINB1, ELAVL2, ELF1, ELF3, ELK1, ELK3, EMP2, EMX1, EMX2, EN1, ENSA, SLC29A1, EP300, EPHA3, EPHA4, EPHA5, EPHB1, EPHB2, EPHB3, EPOR, EYA4, ERCC3, ERCC4, ERCC6, ERF, ERG, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV3, ETV4, ETV5, ETV6, EVPL, EVX1, EWSR1, EYA2, EZH1, F2R, F3, F12, FANCE, FANCB, FANCF, FANCG, FBLN1, FBN1, EFEMP1, FCER2, FCN2, FGA, FGF3, FGF4, FGF6, FGF8, FGF9, FKBP3, FKBP5, FOXD1, FLII, FLOT2, FLT3LG, FLT4, AFF2, FNTA, FPR1, FYB, IFI6, GAS1, GATA4, OPN1MW, GDF9, GDNF, GFAP, GFER, GLE1, GNAQ, GNG3, GP1BA, GP9, GPX2, GRB2, RAPGEF1, GRM1, GSC2, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, GZMH, GZMK, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, H3F3B, HBE1, HCLS1, HDGF, CFHR1, HHEX, HIC1, HIP1, HIVEP2, HLF, HMGN1, HMGCS2, HMGA1, NR4A1, HMX2, HNF4G, HNRNPC, HOXC10, HOXC11, HOXD4, HOXD8, HOXD9, HOXD10, HOXD12, HP, HRC, HRG, PRMT1, HSBP1, HSD11B1, HSF4, HSPA9, IAPP, ICAM1, ID1, ID2, IFI16, SP110, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNW1, IGF1R, IGFBP6, RBPJ, IL1A, IL1RAP, IL1RN, IL2RA, IL2RB, IL2RG, IL3, IL12B, IL12RB2, IL13, IL18, ILK, INCENP, ING2, INHA, INSRR, IRAK1, ITGA6, IRAK2, IRF1, IRF5, ISL1, ITGA1, ITGA5, ITGAV, ITGB1, IVL, JARID2, JUN, JUNB, JUND, JUP, KCNH2, KCNK2, KCNQ1, KDR, KISS1, KLK1, KLK2, KLKB1, KNG1, KPNA2, LIMK1, LIMK2, LMO1, LTF, SMAD1, SMAD6, SMAD9, MARK3, MAZ, MEN1, MEOX2, MFGE8, KITLG, MGMT, CIITA, MAP3K11, AFF1, FOXO4, PPP1R12A, DRG1, TONSL, NRF1, YBX1, NTRK3, DDR2, NVL, OAS3, OLR1, ORC1, ORC2, ORC4, OTX1, OTX2, OVOL1, OXTR, PRDX1, SERPINE1, PAX2, PAX3, PAX9, SERPINA5, PCMT1, PCNA, PCOLCE, CHMP1A, PCP4, PDPK1, SERPINF1, PEG3, PEX12, PFDN2, PFN2, PGR, PHF2, SERPINA4, SERPINB5, SERPINB6, SERPINB9, SERPINI1, SERPINB13, SERPINI2, PPIB, PPID, PPM1B, PPP1R7, PPP2R1B, PPP4C, PPP5C, PRCP, PREP, PRG2, PRIM2, PRKAR1A, PRKAR1B, PRKAR2A, PRKCB, PRKCI, PRKCQ, PRKG1, PRKX, PRL, PRSS8, KLK10, PSKH1, PTCH1, PTMA, PTMS, PTPN4, PTPN6, PTPN7, PTPN9, PTPN12, PTPN14, PTPRA, PTPRE, PTPRH, PTPRJ, PTPRN, PTPRN2, PTPRR, PTPRS, PTPRZ1, PURB, PZP, RAB3B, RAB5A, RAB6A, RAB27A, RABGGTA, RABGGTB, RAC2, RAD21, RAD51, RAD51C, RAD51B, RAD51D, RAG1, RAG2, RAN, RANGAP1, RAP1A, RAP2A, RAP2B, RARB, RASA2, RBBP4, RBBP8, RBL2, RBMS1, RBMS2, RBP2, OPN1LW, DPF2, RET, REV3L, RFC1, RFC3, RFC4, RFC5, RFX1, RFX3, RFX4, RFXAP, RGR, RGS12, RHEB, RLBP1, RLF, RNASE1, RNF2, RP9, RPA2, RPA3, RPS6KA2, RRAS, RXRG, RYK, RYR2, S100A1, SORT1, S100A7, S100A8, S100A11, S100A12, SALL1, SATB1, SBF1, ATXN7, SERPINB4, CCL22, CCL25, XCL1, CX3CL1, SELE, SET, SFPQ, SFRP5, SRSF1, SRSF5, SRSF7, SFSWAP, TRA2B, SFTPD, SGK1, SHC1, STIL, SIM2, SIX3, SLAMF1, SLC6A4, SLC12A1, SLPI, SMARCA1, SMARCA2, SMARCA4, SMARCD3, SMARCE1, SNAI1, SNAPC3, SNAPC4, SNRNP70, SNRPA, SNRPA1, SNRPC, SNRPD1, SNRPE, SNRPF, SNTA1, SOD2, SOX3, SOX5, SOX10, SP1, SP2, SP3, SP100, SPG7, SPIB, SPINK1, SPOCK1, SPRR2A, SPRR2D, SPRR2E, SPRR2G, SPRR3, SQLE, SRF, SRPK2, SRY, TRIM21, SSRP1, ST14, STAT2, STAT4, STAT6, STK10, STYX, XCL2, T, ADAM17, TAF4B, TAF7, TAF10, TAL1, TARBP1, CNTN2, TBCD, TBCE, SERPINA7, TBP, HNF1A, GCFC2, ZNF354A, PRDX2, NR2F1, NR2F2, KLF10, NR2E1, TMPO, CLEC3B, TNNI2, TOP1, TOP2A, TOP2B, TP73, TPD52L1, TPMT, TPSAB1, NR2C1, NR2C2, TRAF1, TRIO, TRIP6, TRPC1, TRPS1, TSN, TTF1, TUBA4A, TULP3, TNFSF4, TYK2, TYRO3, UBE2E2, UBE2V1, SCGB1A1, COL14A1, KDM6A, UTY, VAV1, VBP1, VDR, VIL1, VIM, TRPV1, VRK1, VTN, WNT11, WRN, XPA, XRCC2, XRCC5, YY1, YWHAZ, ZFP37, ZFPL1, ZFX, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF33B, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF221, ZNF91, ZNF99, ZNF124, ZNF131, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF177, ZNF180, ZNF189, ZNF208, ZNF214, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZXDA, PRDM2, PTP4A1, LRP8, TUBA1A, FZD5, SCG2, MAFK, ARHGEF5, FOSL1, CDK2AP1, IFT88, ANP32A, AKAP1, SF3A2, ZNF239, DPF1, NRIP1, CHAF1B, RBM10, KDM5C, SMC1A, KDM5D, ARID1A, HIST1H4I, CDC45, EOMES, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, BCAR3, LTBP4, ZNF282, NR0B2, UTF1, DUSP11, TTF2, TPST2, TPST1, KLF11, SMARCA5, FKBP6, SEMA7A, PPM1D, IKBKG, IKBKAP, HAT1, GAS7, AGPS, PIR, FCN3, BLZF1, CDC14B, MADD, RRP1, PRKRA, STK16, RGS20, RUVBL1, RDH16, KLF7, TP63, CHRD, PEA15, SRSF9, SERPINB7, TRADD, EED, ADAM19, CRADD, TNFSF14, TNFSF13, TNFSF10, ADAM15, RIPK2, RIOK3, TNFRSF18, DLK1, TNFRSF10B, TNFRSF10A, DYRK4, PEX11A, CREG1, CDKL1, SAP30, HESX1, IQGAP1, NRP1, ALKBH1, PER3, TAX1BP1, BUD31, PHOX2B, FUBP3, HIST1H3F, HIST1H2AG, RPS6KA4, TNFSF18, CDKL2, TAF1B, TAF1A, SOCS3, BAZ1B, UBA3, DIRAS3, UNC119, LATS1, ATP6V0D1, PDLIM1, SMC3, PRPF3, CBFA2T2, DYRK1B, CTDP1, EXO1, SCAF11, ARHGEF2, DDX21, DCLK1, BMP15, RAB11B, CCPG1, RPS6KA5, STK17B, STK17A, ITGB1BP1, GPR55, ZNF235, COPS2, TRIP11, HMGN3, TRIP4, GTF3C5, GTF3C4, GTF3C3, EFTUD2, SLIT2, SLC9A3R1, ZFYVE9, RECQL5, ZRANB2, TMPRSS11D, SNRNP40, DDX23, HAND1, ZNF264, FHL5, PICK1, IL27RA, ATG5, ONECUT2, ADAMTS4, ADAMTS3, ADAMTS2, LITAF, GDF15, BAG4, BAG2, ZNF254, GMFG, CIR1, NRG2, APBA3, CHD1L, BRE, CDC42BPB, SOX13, PREPL, RBM39, CREB5, TRAF4, KLK4, AATK, PPM1F, TTLL4, ZNF516, SAFB2, PHF14, KDM4A, VGLL4, BZW1, KIAA0391, RAPGEF2, RIMS2, ST18, ADAMTSL2, UTP14C, ZNF646, VPRBP, SETD1A, ZNF536, SLK, ZFYVE16, RASSF2, ATG13, DHX38, TOMM20, SCRN1, KIAA0141, SFI1, RB1CC1, ARHGEF11, DNAJC6, GINS1, ZEB2, ZBTB24, ZNF518A, ZC3H11A, NUAK1, RNF10, ZBTB5, JOSD1, DCLRE1A, OXSR1, TNFSF15, NR1I3, NR1D2, REC8, DMTF1, CASP8AP2, NR2E3, ZBTB33, PDCD6, BCL2L11, SH2D3C, SH2D3A, RANBP9, UBA2, SAE1, DPP3, PTPRU, PDCD7, PQBP1, CTDSP2, SGK2, RAD50, FEM1B, ZNF263, FRY, YAF2, AKAP9, G3BP1, SUGP2, ABI2, TRIM28, RASA4, FARP1, ZNF197, ZNF256, ALYREF, DHRS2, OLIG2, PRG4, CTDSPL, SPRY1, DENND4A, IRX5, RAMP3 |
1796 | GO:0048518 | 0.00 | 1.46 | 65.45 | 85 | 268 | positive regulation of biological process | ACTA2, ACTG2, AMPH, TRIM23, ARHGDIB, ARHGDIG, ARL1, RCBTB2, CLPS, DHFR, EIF2B1, GCGR, GDI1, GDI2, GM2A, GNA15, GNAQ, GNAT1, HSPB2, LLGL2, PPP1R12B, OCRL, OPHN1, SERPINB9, RAB4A, RABIF, RANBP1, RANGAP1, RFC1, RGS1, RGS10, RGS12, RGS13, RPGR, SBF1, SFTPB, SIPA1, TBCD, KDM6A, VIM, WRN, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SMARCA5, RGS20, S1PR4, RGS9, EIF2B3, EIF2B2, HERC2, HIST1H3F, TAF1B, TAF1A, RABEP1, ARHGEF1, DDX21, CYTH2, TRIP10, GTF3C4, ARHGAP29, SEC22B, RIN1, RALGPS1, USP6NL, ARHGAP32, ACAP1, RGP1, SGSM2, DENND4B, ARHGAP25, UBA2, FARP1, RASGRP2, DENND4A |
1797 | GO:0006811 | 0.00 | 1.46 | 82.01 | 105 | 289 | ion transport | ABAT, ABCA2, ABCA4, ADA, ADCYAP1R1, AGTR2, ALB, ABCD1, ANXA1, ARG1, ATF4, TSPO, CA1, CA4, CA6, CAMK2A, CAMK2G, CD4, CD36, SCARB1, CD63, CDK2, CDK5, AKR1C4, CHRM1, CLNS1A, CLTC, CCR1, CNR1, CRY2, SLC25A10, CTGF, CTNS, CYP27B1, ACE, FCER1A, FTL, FYN, GDNF, GIF, GJA4, GOT2, GPM6B, FFAR1, HBA1, HBA2, ICAM1, IGF1, IREB2, LTF, NTRK2, P2RY2, P2RY4, P2RY6, PCP4, PRKCB, PRSS8, PTGS2, ABCD3, RAB3A, RAB3B, RCVRN, RXRA, SCO1, SEC14L1, SLC2A2, SLC5A2, SLC6A4, SLC6A13, SLC10A1, SLC15A1, SLCO2A1, SLCO1A2, SNAP25, SYK, SYT1, TACR2, TAF7, TPT1, TRH, TSC1, UCP1, VDR, VIP, WFS1, TUSC3, FGF23, SLC10A3, PICALM, CYP4F2, VAMP8, ABCC3, SNAP23, CD84, SLC25A14, SLC13A2, CLDN10, SLC6A5, RAB11B, SLC22A14, NR1H4, ABCC5, ATP9A, ABCC4, RAMP3 |
1798 | GO:0032102 | 0.05 | 1.46 | 28.84 | 37 | 99 | negative regulation of response to external stimulus | ABAT, ANGPT2, ANXA5, APOH, BBS4, PRDM1, TSPO, EPHA4, F2, F12, FAP, FGA, GCG, GP1BA, HMGCR, HRG, IFIT1, KLKB1, KNG1, LTF, SERPINE1, PCBP2, PPM1B, PRKG1, PROS1, SEC14L1, SEMA3F, TARBP2, TNR, TSC1, USF1, VTN, SEMA3B, NRP1, FEZ2, RUBCN, SEMA3E |
1799 | GO:0044711 | 0.00 | 1.45 | 245.40 | 308 | 847 | single-organism biosynthetic process | ABAT, ABCA1, ACACB, ACADM, ACAT1, ADCY1, ADCY7, ADCYAP1R1, ADSS, NR0B1, AHCY, AK1, AK2, ALDH1A3, ALDH3A2, ALDOC, ALOX15B, AMPD1, AMPD2, ANG, ANGPT1, AQP1, ARF1, ASNS, ASPA, ATF3, ATF4, ATP1A1, ALDH7A1, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V0A1, ATR, AVPR2, BCAT2, BHMT, BMP4, BPGM, C3, CALM3, SCARB1, CDA, CDO1, CHAT, AKR1C4, CHKA, CHKB, CLTC, COL1A1, CREB1, CRH, VCAN, CSPG4, SLC25A10, CTGF, CTH, CYP1A2, CYP3A4, CYP8B1, CYP11B1, CYP27B1, DCN, DDB1, DHCR7, DHFR, DHPS, CYB5R3, DKC1, DLD, DPH2, DRD3, DRD5, TYMP, LPAR1, EDNRA, EDNRB, EIF5A, ENO2, ESD, EXT2, EXTL1, EXTL3, F2, F2R, PTK2B, FDFT1, FDPS, GPC4, FGF7, GPC5, FSHB, FSHR, FUT8, G6PC, GAD1, GALR1, GAPDH, GARS, GATM, GCG, KAT2A, B4GALT1, GHRHR, GPC3, GLUD1, GMDS, GNAI3, GNAS, GOT2, GPC1, GPD2, GPI, GPLD1, GPT, GSS, GSTZ1, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GUK1, GYS2, GUCY2D, HADHA, HARS, HAS1, HAS2, HAS3, HEXA, HEXB, HMGCR, HMGCS2, HNRNPC, HRH1, HSD11B1, HSD17B3, HSD17B4, HTR2C, IDH1, IFNG, IGF1, IGF2, IHH, IMPDH1, IMPDH2, IDO1, INS, INPPL1, INSIG1, ITGA2, LCAT, LDHC, LIPC, MDH2, MGAT2, CIITA, NTRK2, NTSR1, OAS1, OAT, OCRL, ODC1, OMD, P2RX1, P2RX7, P2RY11, PAH, PALM, PCK1, PCK2, PCYT1A, PDK4, PEX7, PFAS, PGAM1, PGD, PHKG1, PIK3C2A, PIK3C2B, PI4KA, PIP4K2A, PPP1CA, PPP1R3C, PPT1, PRKAA1, PRKAB2, PRKACB, PRKACG, PRKAG1, PRKD1, PRKCQ, MAPK1, MAPK3, PROX1, PRPS2, PRPSAP1, PSPH, PTAFR, PTEN, PTH, PTPN2, ABCD3, PYCR1, RAF1, RANBP2, RAP1A, RBP1, RCVRN, REST, REV3L, RPS27A, RRM1, RRM2, ACSM3, SDC1, SDC4, SHMT2, SMPD1, SNAI1, SNCA, SORD, UAP1, SQLE, SRD5A1, SREBF1, STAT3, ELOVL4, TAZ, TNFRSF1A, TUFM, TYMS, UBB, UBA7, UFD1L, UGT8, NR1H2, UPP1, VDR, VIP, VIPR2, WFS1, CNBP, TRIM25, ZP3, PDHX, NSMAF, DYRK2, CUL4A, OGT, PIK3R3, DGKE, AGPS, SLC25A12, TNKS, ALDH4A1, DGAT1, B4GALT4, B4GALT3, B3GALT2, SERPINB7, SUCLG1, DPM2, INPP4B, SYNJ1, SGPL1, KYNU, PAPSS1, RGN, AURKB, VAPB, VAPA, B4GALT6, GSTO1, GGPS1, CHST3, AKAP6, PIGL, ADAMTS3, TBPL1, MPDU1, GABBR2, NR1D1, AKAP12, GUCA1C, HS2ST1, SDC3, PTDSS1, EPM2AIP1, XYLB, HS3ST3B1, HS3ST1, NR1H4, RBX1, GNE, PIGK, ABCC5, COL4A3BP, UST, RAD50, SLC25A13, DHRS9 |
1800 | GO:0036211 | 0.00 | 1.45 | 641.51 | 775 | 2192 | protein modification process | ABCA1, ABL1, ABL2, ABO, ACP1, ACP2, ACTL6A, ACVR1B, ACVR2B, ACVRL1, ADAM8, ADAM10, ADAR, ADCY1, ADCY7, ADH5, ADPRH, ADRA1B, ADRBK1, AGTR2, ALK, ANG, ANGPT1, ANXA1, APBB1, BIRC3, XIAP, BIRC5, APLP2, APP, ARAF, ARCN1, TRIM23, ARF4, ARNT, ARR3, ARSA, STS, ARSD, ARSE, ARSF, ART1, ASL, ATF3, ATP6AP1, ATR, AVPR2, AXL, BACH1, BARD1, BAX, OPN1SW, BCR, BDKRB1, BGLAP, BHMT, BLK, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, BMX, BRCA2, BTK, BUB1, BUB1B, TSPO, C3, CALM3, CAMK2A, CAMK2G, CANX, CAV3, CBL, CBLB, CCNB1, CCNC, CCNE1, CCNF, CCNT2, CD3E, CD4, CD36, CD40, CD44, CD59, CD74, CDK11B, CDC6, CDC20, CDC25A, CDC25C, CDC27, CDK2, CDK3, CDK4, CDK5, CDK6, CDK8, CDKN1A, CDKN2D, CENPE, CENPF, CHAD, CHEK1, CHRM1, CHRM3, CHUK, CKS1B, CLU, CLK1, CLK3, CCR1, COPA, COPB1, CREB1, CRH, CRKL, CRY2, CRYAB, CRYBA1, CSF1R, CSF2, CSF2RB, CSNK1D, CSNK1G3, CSNK2A1, CSNK2A2, CSPG4, CTF1, CTGF, CTH, CTSG, CTSH, DAD1, CD55, DAPK3, DCN, ACE, DDB1, DHPS, DLG2, DLG3, DYNC1H1, DNMT1, DNMT3B, DPH2, DTX1, DUSP1, DUSP5, DUSP7, DUSP9, E4F1, LPAR1, EDNRA, EDNRB, PHC2, EFNA1, EFNA5, EGR2, EHHADH, EPHA2, EIF5A, ELK1, EMP2, ENSA, EP300, EPHA3, EPHA4, EPHA5, EPHA8, EPHB1, EPHB2, EPHB3, EPOR, EYA4, ERCC3, ERCC6, ERG, EVPL, EXT2, EXTL1, EYA2, EZH1, F2, F2R, F7, F10, PTK2B, FANCF, FBLN1, EFEMP1, FCER1A, FGA, FGF3, FGF4, FGF6, FGF7, FGF8, FGF9, FGFR3, FGR, FKBP3, FKBP5, FLT1, FLT3, FLT3LG, FLT4, FNTA, FPR1, FSHR, FUT6, FUT8, FYB, FYN, GAD1, GAPDH, GATA3, GCG, KAT2A, OPN1MW, GDF9, B4GALT1, GMDS, GNAQ, GNG3, GOLGA2, GOLGB1, GP1BA, GPLD1, GPX1, GRB2, RAPGEF1, GRIA1, GRIN2A, GRM1, GUCY2C, GUCY2F, GUCY2D, HIST1H1B, HCLS1, HGF, NRG1, HHEX, UBE2K, HLCS, HMBS, HMGCR, HNRNPC, HPN, HPX, HRC, HRG, PRMT1, HSF4, DNAJB2, HSPB1, HTR2C, ICAM1, ID1, IFNA2, IFNA5, IFNA13, IFNA17, IFNA21, IFNG, IFNW1, IGF1, IGF1R, IGF2, IGFBP3, IL1A, IL2RA, IL2RB, IL2RG, IL3, IL12B, IL12RB2, IL13, IL18, ILK, INCENP, INHA, INS, INSRR, IRAK1, IRAK2, ISL1, ITGA1, ITGA2, ITGA5, ITGAV, ITGB1, IVL, JARID2, JUN, KCNH2, KDR, KISS1, KIT, LIMK1, LIMK2, LIPE, LTF, MAD2L1, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAN2B1, MARK3, MDH2, MEN1, MGAT2, MGAT3, KITLG, ATXN3, MAP3K11, PPP1R12A, CNOT4, NTRK2, NTRK3, DDR2, NUP98, OXTR, P2RX7, P4HA1, PRDX1, PAH, PAM, PCK1, PCMT1, PCNA, PCP4, PDK4, PDPK1, PEX12, CFP, PFN2, PHB, PHF2, PHKA2, PHKB, PHKG1, PIM1, PPIB, PPID, PPM1B, PPP1CA, PPP1R3C, PPP1R7, PPP2CB, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PPP4C, PPP5C, PPP6C, PPT1, PRKAA1, PRKAB2, PRKACB, PRKACG, PRKAG1, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCB, PRKCE, PRKCI, PRKD1, PRKCQ, PRKCSH, PRKG1, MAPK1, MAPK3, DNAJC3, PRKX, PROC, PROS1, PROX1, PSAP, PSKH1, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, PTPN2, PTPN3, PTPN4, PTPN6, PTPN7, PTPN9, PTPN12, PTPN14, PTPRA, PTPRE, PTPRH, PTPRJ, PTPRN, PTPRN2, PTPRR, PTPRS, PTPRZ1, RAB1A, RAB3B, RAB6A, RABGGTA, RABGGTB, RAC1, RAC2, RAD21, RAD51, RAF1, RAG1, RAG2, RANBP2, RANGAP1, RAP1A, RAP2A, RAP2B, RARA, RASA2, RB1, RBBP6, RBM4, OPN1LW, REST, RET, RGR, RNF2, RNF6, RPS3, RPS6KA1, RPS6KA2, RPS6KA3, RPS6KB1, RPS6KB2, RPS27A, RRAS, RYK, S100A7, S100A8, S100A9, S100A12, SALL1, SATB1, SBF1, ATXN7, CCL21, CCL22, CCL25, XCL1, CX3CL1, SDC4, TRAPPC2, SET, SETMAR, SFPQ, SGK1, SHC1, SHMT2, SIAH2, STIL, SKP1, SKP2, SLAMF1, SMPD1, SUMO3, SNCA, SNTA1, SORL1, SOX4, SOX9, SP3, SP100, UAP1, SPINK1, SPRR2A, SPRR2D, SPRR2E, SPRR2G, SPRR3, SPTA1, SPTB, SREBF1, SRPK2, TRIM21, STAT4, STK10, STYX, XCL2, SYK, ADAM17, TAF7, TAF10, TARBP2, TBL1X, NR2F2, TNFRSF1A, TNFRSF1B, TOP1, TOP2A, TOP2B, TP73, TPD52L1, NR2C2, HSP90B1, TRAF2, TRIO, TRPS1, TSC1, TSG101, TTC3, TTK, TYK2, TYRO3, UBB, UBA7, UBE2D1, UBE2D2, UBE2E2, UBE2H, UBE2L3, UBE2V1, UBE3A, SUMO1, USP4, KDM6A, UTY, UVRAG, VEGFA, VEGFB, VRK1, VTN, WFS1, WNT1, WNT11, WRN, TRIM25, ZNF207, ZP3, PRDM2, PTP4A1, LRP8, RNF103, FZD5, SCG2, AIMP2, ARHGEF5, TUSC3, NUP214, FGF23, AAAS, CDK2AP1, GAN, AKAP1, USP11, USP9X, KDM5C, SMC1A, KDM5D, USP9Y, HIST1H4I, BAP1, FZD4, FZD7, FZD8, GFI1B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, BCAR3, DYRK2, DUSP11, CUL4A, CUL3, CUL2, CUL1, TPST2, TPST1, FKBP6, OGT, SEMA7A, PPM1D, IKBKG, IKBKAP, HAT1, COPS3, CDC14B, MADD, PRKRA, STK16, RUVBL1, USO1, PDE5A, DYNLL1, TNKS, EIF3F, PEA15, GALNT4, CDC23, B4GALT4, B4GALT3, B3GALT2, EED, RIPK1, RIPK2, RIOK3, TNFRSF18, TNFRSF10B, TNFRSF10A, DYRK4, CDKL1, DPM2, IQGAP1, NRP1, PROZ, CDC16, HERC2, P4HA2, RPS6KA4, TNFSF18, CDKL2, SOCS3, RNF8, BAZ1B, UBA3, DIRAS3, UNC119, USP14, USP6, USP2, USP8, RGN, LATS1, SMC3, DYRK1B, CTDP1, ARHGEF2, ZW10, BUB3, DCLK1, BMP15, AURKB, VAPB, RPS6KA5, STK17B, STK17A, ITGB1BP1, COPB2, GPR55, SOCS6, KLF4, COPS2, TRIP12, GTF3C4, B4GALT6, SLIT2, UBE4A, KL, SLC9A3R1, COG1, EIF2AK3, PICK1, AKAP6, ATG5, PIGL, PSMF1, GDF15, GOSR1, TMEM59, BAG5, BAG4, GMFG, NRG2, SEC22B, GOSR2, CLOCK, BRE, CDC42BPB, RNF14, RNF7, TRAF4, AATK, NUP155, PPM1F, TTLL4, KDM4A, NUP93, UBE3C, RAPGEF2, VPRBP, USP34, SETD1A, SLK, RASSF2, ATG13, DLGAP5, SPOCK2, RNF40, SFI1, CUL7, RB1CC1, DNAJC6, ZEB2, AREL1, NUAK1, KLHL21, RNF10, OXSR1, USP3, TNFSF15, NR1H4, RBX1, HDAC6, GNE, PIGK, PARP3, SH2D3C, SH2D3A, RANBP9, UBA2, SAE1, PTPRU, COL4A3BP, UST, CTDSP2, SGK2, RAD50, FEM1B, FRY, AKAP9, ABI2, TRIM28, RASA4, ATP6AP2, FARP1, CHST4, RNF41, PSME3, PSMD14, CTDSPL, SPRY1 |
1801 | GO:0006066 | 0.01 | 1.45 | 61.17 | 78 | 209 | alcohol metabolic process | ABCA1, ADCYAP1R1, ADH5, ALDH1B1, ALDH1A3, ALDH3B2, ALDH3A2, APOF, APLP2, APP, ALDH7A1, BCHE, CALM3, CAT, SCARB1, CHAT, CHKA, CHKB, CYP3A4, CYP8B1, CYP11B1, CYP27B1, DBI, DHCR7, CYB5R3, PTK2B, FDFT1, FDPS, FGF7, GK2, GPD2, GPLD1, HMGCR, HMGCS2, HRH1, HSD17B3, IFNG, IGF1, INPP1, INPPL1, INSIG1, LCAT, LIPA, LIPC, LIPE, NTSR1, OCRL, PCK1, PCYT1A, PRKAA1, PTAFR, PTEN, REST, RXRA, SLC34A1, SMPD1, SNAI1, SNCA, SORD, SORL1, SQLE, SREBF1, TNFSF4, VDR, CNBP, FGF23, NR0B2, AKR1C3, DGAT1, DPM2, INPP4B, SYNJ1, GGPS1, MINPP1, PPIP5K1, SNX17, NR1H4, DHRS9 |
1802 | GO:0051128 | 0.00 | 1.45 | 184.11 | 232 | 645 | regulation of cellular component organization | ACTL6A, ACVR1B, ADAM10, AGTR1, AGTR2, AHR, BIN1, ANGPT1, APAF1, APBB1, APBB2, BIRC5, AQP1, ARF1, ARL2, FXYD2, ATR, AXL, BAD, ADGRB2, BAX, BCR, BDKRB1, BICD1, BIK, BLK, BNIP3L, BST2, KLF5, C3, CAPN6, CASP8, CBL, CD14, CD28, CD36, SCARB1, CD63, CDA, CDK11B, CDC6, CDC25C, CDKN1A, CDKN2D, CENPE, AP2S1, CNR1, CREB1, CRYAB, CSF2, CTGF, CTSK, CYBA, CYP27B1, DBN1, DCN, DHODH, DKC1, DRD3, EIF5A, EPHA5, EPHB1, EPHB2, EPOR, ETV5, EXTL3, FGF8, FLT3LG, GATA3, GCG, KAT2A, GDF9, GHSR, GPC3, GPM6A, GPR3, GPR26, GRB2, GRID2, HIST1H1B, H3F3B, HAS3, HCLS1, HIP1, HNMT, IGF1R, IGF2, IGFBP3, IGFBP6, IL1A, ING1, ISL1, ITGA2, ITGAV, JUN, LCAT, MFGE8, CNOT2, OPHN1, OXTR, P2RX7, P2RY2, SERPINE1, PAM, CHMP1A, PCP4, SERPINF1, PFDN2, PHB, PIP4K2A, EXOSC9, PPP2R1A, PPT1, PRKCE, PRKCQ, MAPK1, MAPK3, PROS1, PROX1, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMD8, RAB3A, RAB4A, RAB5A, RAB5B, RAB27A, RAC2, RALA, RB1, UPF1, RNASE2, RPL28, RPS3, RPS6KA1, RPS6KA3, CLIP1, S100A8, SDC1, SELE, SELP, SFPQ, SFTPD, SIPA1, SLAMF1, SMARCA2, SMARCA4, SNAP25, SREBF1, SUPV3L1, SURF4, SYK, ADAM17, TAL1, HNF1A, DYNLT1, TPBG, TRPS1, TSG101, TULP1, UBE2L3, SUMO1, COL14A1, CLRN1, VDAC1, VTN, WAS, WNT1, WNT11, YWHAZ, ZBTB17, ARHGEF5, FOSL1, SF3A2, BAP1, CDC45, GFI1B, LTBP4, CUL3, BLZF1, RUVBL1, DYNLL1, EED, HRK, TNFSF14, TNFSF10, ADAM15, WISP3, SYNJ1, RPS6KA4, CDKL2, LATS1, CTDP1, RPS6KA5, KLF4, RAB33A, NRXN3, AKAP6, GDF15, SEC22B, BCAR1, MAD2L1BP, USP6NL, KNTC1, FRMPD4, ZFYVE16, ATG13, PIEZO1, SNX17, DLGAP5, RNF40, ARHGEF11, DNAJC6, ZEB2, C2CD5, SNAP91, FAM20B, WDR1, PDCD6IP, BCL2L11, PARP3, SAE1, ARPC5, ARPC1B, ACTR3, ACTR2, SGK2, ABI2, RASGRP2 |
1803 | GO:0032268 | 0.00 | 1.45 | 140.47 | 178 | 509 | regulation of cellular protein metabolic process | ADAR, BIRC5, APLP2, AQP1, ARR3, ATF3, ATF4, BDKRB1, BST2, TSPO, CCNE1, CD59, CDC25A, CDC25C, CDK2, CDKN2D, CHAD, CHEK1, CKS1B, COL6A3, CRY2, CRYAB, CRYBA1, CST1, CST6, CD55, DAPK3, DCN, DDX1, DDX6, DLG2, DLG3, DPEP1, ECM1, EIF2B1, EPHA2, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4EBP2, EIF4G2, EIF5, SERPINB1, ENSA, EP300, EPHB1, EPRS, FGR, IFI6, GAPDH, GAS1, GATA3, GPC3, GNAQ, GP1BA, GPI, GRB7, HHEX, HRC, HRG, HSPB1, ID1, IL10, EIF3E, IREB2, ITIH1, ITIH2, ITIH4, KNG1, LIMK1, CAPRIN1, SMAD1, SMAD6, MEN1, CNOT2, PA2G4, PRDX1, SERPINE1, PAX2, SERPINA5, PCP4, SERPINF1, SERPINA4, SERPINB5, SERPINB6, SERPINB9, SERPINI1, SERPINB13, SERPINI2, PPP1CA, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PRKAB2, PROS1, PTPN2, PTPN3, PTPN6, PTPRJ, PTPRR, PURA, PZP, RAC2, RAD51, RAG1, RAN, RARA, RBM4, RENBP, UPF1, RPL38, RPS6KA1, RPS6KA3, RRAS, SERPINB4, SET, SIAH2, SLPI, SNRNP70, SNTA1, SORL1, SPINK1, SPOCK1, SRP9, TRIM21, STYX, TAF7, SERPINA7, NR2F2, HSP90B1, TRPS1, TSC1, TSG101, USP4, UVRAG, VIL1, EIF4H, AKAP1, GFI1B, IKBKAP, PRKRA, EIF4EBP3, EIF3F, EIF3G, EIF4G3, SERPINB7, TNFSF14, EIF2B3, EIF2B2, SOCS3, DIRAS3, SOCS6, TRIP12, SLIT2, SLC9A3R1, ATG5, TMEM59, GMFG, EIF5B, KDM4A, PUM1, SFI1, NUAK1, RBM8A, HDAC6, RANBP9, CTDSP2, FEM1B, FRY, TRAP1, ATP6AP2, FARP1, RNF41, EIF1, CTDSPL, SPRY1 |
1804 | GO:0043241 | 0.03 | 1.44 | 40.04 | 51 | 137 | protein complex disassembly | ADD1, CAPG, CCNB1, EIF5A, FAU, NRG1, CHMP1A, PPP1CA, UPF1, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, SGK1, SPTA1, SPTB, VIL1, SYNJ1, RPL14, ARHGEF2, AURKB, RPL23, DNAJC6, WDR1, HDAC6 |
1805 | GO:0072330 | 0.04 | 1.44 | 34.53 | 44 | 118 | monocarboxylic acid biosynthetic process | ABAT, ACACB, ACADM, ALDH1A3, ALOX15B, ANXA1, CBR1, CD74, AKR1C4, VCAN, CSPG4, CYP8B1, DCN, FCER1A, GAD1, GGT7, HPGD, HSD17B4, IDO1, INSIG1, LDHC, LIPC, LTA4H, PDK4, PRKAA1, PRKAB2, PRKAG1, PROX1, PTGIS, PTGS1, PTGS2, ABCD3, RBP1, ACSM3, SHMT1, ELOVL4, SYK, NR1H2, AKR1C3, RGN, NR1D1, NR1H4, UST, DHRS9 |
1806 | GO:1901617 | 0.04 | 1.44 | 32.98 | 42 | 113 | organic hydroxy compound biosynthetic process | ACADM, ADCYAP1R1, CHAT, AKR1C4, CHKA, CHKB, CYP3A4, CYP8B1, CYP11B1, CYP27B1, DHCR7, CYB5R3, PTK2B, FDFT1, FDPS, FGF7, HMGCR, HMGCS2, HRH1, HSD17B3, HSD17B4, IFNG, INSIG1, LCAT, LDHC, NTSR1, PCK1, PCYT1A, PRKAA1, PROX1, PTAFR, REST, SHMT1, SNAI1, SQLE, SREBF1, VDR, CNBP, AKR1C3, GGPS1, NR1D1, NR1H4 |
1807 | GO:0007154 | 0.00 | 1.44 | 389.11 | 476 | 1544 | cell communication | ABCA4, ACTB, ADCYAP1R1, ADD1, APLNR, AHR, ANG, ANGPT2, ANXA4, ANXA6, APBB1, APBB2, KLK3, TRIM23, ARF4, ARF5, RND3, ARL1, ARR3, ATP2A1, ATP6V1B2, ATP6V1E1, ATP6V0B, ATRX, AVPR1B, AVPR2, ADGRB2, BBS4, BCL2A1, BCL9, TNFRSF17, OPN1SW, BDKRB1, BMX, BOK, DST, BRCA2, BSG, BTK, BUB1B, CAPN5, DAGLA, CAMLG, CAPS, CASP9, CASQ1, KRIT1, CCNC, CCNT2, CD3D, CD3G, CD5, CD6, CD7, CD9, TNFRSF8, SCARB1, CD37, ENTPD2, CD59, CD69, CD72, CD151, CDA, CDC25C, CDH1, CDH6, CDK2, CDK4, CDK6, CDK8, CENPA, CENPE, CENPF, AKR1C4, CHKA, CLCN6, TPP1, CLPS, CCR3, CCR8, COL4A3, COL15A1, CLDN3, CR1, CR2, CRYAB, CSH1, CSNK1G3, CTLA4, CTSS, DGKB, DCC, DDB1, DDX11, DIAPH1, DIAPH2, DMBT1, DOK1, DPP6, E2F5, S1PR1, EDNRB, CELSR2, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4G2, ELK1, ELK3, ADGRE1, EPHA3, EPHB2, EPHB3, ERG, ESRRG, ETV2, EXT2, EXTL3, EYA2, F2RL2, EFEMP1, FCER2, FCGR2A, FCGR2B, FCGRT, GPC4, GPC5, FLT3LG, FPR2, FPR3, FSHB, CENPI, NR5A2, FUT8, ACKR1, FYB, GABRE, GCGR, OPN1MW, GEM, GFRA1, B4GALT1, GH2, GMDS, GNA15, GNAQ, GNAT2, GNRH2, GNRHR, GPR3, GPR4, XCR1, GPR15, GPR17, GPR19, LPAR4, GPR25, GPR26, GRID1, CXCL2, CXCL3, GRPR, GTF2I, GUCY2C, H3F3B, HDGF, HIP1, HIVEP2, NR4A1, HNF4G, HPGD, ICAM2, SP110, IFIT1, IFIT3, IGF2R, IL1R1, IL1RAP, IL10RA, IL11RA, IL12RB2, IL13RA2, IL15RA, TNFRSF9, INCENP, INPP1, INSIG1, INSRR, IRF5, ISG20, ITGA4, ITGA7, ITGA9, ITGAD, ITGAE, ITGAM, ITGB5, JUNB, CD82, KLK2, KLRC3, KPNA1, KPNA2, KPNA3, KPNA4, LIMK1, LSP1, LTBP2, MAD2L1, SMAD1, SMAD9, SCGB2A1, MGAT3, CIITA, FOXO4, PPP1R12A, PPP1R12B, NRCAM, DDR2, NUP98, OAS1, OAS3, OR1F1, OR2C1, P2RY2, P2RY4, P2RY6, PAX2, PDE4B, PDE8A, PF4V1, PIK3C2A, PIK3C2B, PI4KA, PPP2R5D, PPP4C, PRKAB2, PRKAG1, PRKCI, PRKCSH, PRKG1, DNAJC3, PTAFR, PTGDR, PTGER1, PTGER2, PTH2R, RAB4A, RAB5B, RAB6A, RAB27A, RABIF, RALA, RAN, RANBP1, RANBP2, RANGAP1, RAP2B, RARB, RBM4, RBP1, RBP2, OPN1LW, PRPH2, DPF2, RGR, RIT1, RLBP1, RPS6, RPS6KB2, RPS19, RPS27, CLIP1, RSU1, RXRA, RXRG, RYR1, S100A1, SORT1, S100A11, TSPAN31, SCN1A, SCN2A, SCN7A, SCN8A, SCTR, SDC1, SDC4, SELE, SEMA3F, SGK1, STIL, SKP1, SMARCC1, SP1, SPARC, SPOCK1, SRPK2, TRIM21, STAT4, STAT5B, STAT6, STK10, STRN, SULT1A3, T, TACR3, TAF7, TBL1X, NR2F1, NR2F2, TSPAN7, NR2C2, HSP90B1, TRHR, TRPC3, TUFT1, TNFSF4, TYROBP, UBA7, UBE2D1, UBE2D2, UPK1B, SCGB1A1, KDM6A, VIL1, VIM, TRPV1, WAS, LAT2, XPA, ZNF217, IL1R2, FZD3, NUP214, AAAS, ANP32A, RND2, MADCAM1, NRIP1, CLTCL1, USP9X, SMC1A, USP9Y, ARID1A, HIST1H4I, FZD9, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, OR1A1, OR1D5, OR1G1, OR3A3, SPARCL1, BCAR3, NSMAF, DYRK2, CUL4A, CUL2, CUL1, SORBS2, PIK3R3, IKBKAP, DGKE, COPS3, UNC5C, SSNA1, OASL, EIF4G3, S1PR4, CTNNAL1, TNFSF13, ADAM15, TNFRSF10D, PEX11B, PEX11A, IL1RL2, NRP2, SGPL1, HIST1H3F, RPS6KA4, ATP6V0E1, PGLYRP1, CDKL2, TAAR5, UBA3, DOK2, PSTPIP1, ANGPTL1, DIRAS3, USP8, ATP6V0D1, SMC3, RASSF9, ZW10, BUB3, REPS2, DCLK1, AURKB, XPR1, VAPB, RPS6KA5, STK17B, STK17A, BCL7B, TAAR2, COPS2, TRIP4, GLP2R, RAB9A, AKAP7, IL27RA, BAG3, ATP6V1G1, BCAR1, GTPBP1, GOSR2, BRE, CDC42BPB, RAB36, AATK, GNA14, PPM1F, ZNF516, SDC3, NUP93, CEP57, SEMA3E, KNTC1, SLK, ZFYVE16, SNX17, KIAA0586, CKAP5, TATDN2, SPOCK2, KIAA0141, CUL7, GAB2, C2CD5, TRIL, NUAK1, P2RY14, OXSR1, NR1I3, NR1D2, CASP8AP2, NR2E3, ZBTB33, TANK, PTPRU, COL4A3BP, ARPC5, ARPC1B, ACTR3, ACTR2, CTDSP2, ARPC2, SGK2, ARL4A, ARFRP1, ABI2, WASF2, RASGRP2 |
1808 | GO:0019222 | 0.00 | 1.44 | 127.97 | 162 | 504 | regulation of metabolic process | ACTA2, ACTB, ACTG2, ADRBK1, AMPH, ANXA5, TRIM23, ARHGAP4, ARHGAP5, ARHGAP6, ARHGDIB, ARHGDIG, ARL1, ARL2, ASIP, ATP6V0A1, AVPR1B, BCL2L1, BCR, BICD1, BNIP3L, CACNA1A, KRIT1, CD63, CDK6, RCBTB2, CHN1, CHN2, CLCN3, CLPS, CNN3, COL2A1, CRP, CTSK, CYBA, CYP1A2, CTTN, EPHA3, EPHB3, FAP, FCER2, FGD1, FUT8, G6PC, GDI1, GDI2, GM2A, GNA15, GNAT1, FFAR1, FFAR3, HK2, HP, HSPB2, IFIT1, INPPL1, ITPR1, ITPR3, KCNQ1, KIF25, IPO5, LLGL2, PPP1R12B, NUP98, OCRL, PIP4K2A, FXYD3, PLN, EXOSC9, PPP1R3C, PPP2CB, PPT1, PRCP, PRKG1, PRPSAP1, PTN, PTPRN2, RAB3A, RAB4A, RAB27A, RABIF, RAG2, RANBP1, RANGAP1, RAP1GAP, RGS1, RGS10, RGS12, RGS13, RPGR, RPL28, RPS19, RSU1, SORT1, SBF1, SELE, SFTPB, ITSN1, SIPA1, SLC6A4, SNCB, SOS2, TBCD, DYNLT1, TNNC1, TNNI3, TOP1, TPM2, TRIO, TSN, KDM6A, UTY, VDAC1, VIM, WAS, WRN, YWHAZ, NUP214, SHOC2, AAAS, FKBP6, DDX3Y, S1PR4, RGS9, DLK1, DPM2, ARHGEF7, HERC2, RABEP1, ARHGEF1, DGKI, DDX21, STK17A, CYTH2, TRIP10, GTF3C4, RAB33A, ARHGAP29, PICK1, CABP1, BAG3, APBA3, RIN1, NUP155, FEZ2, RALGPS1, NUP93, RIMS2, USP6NL, ARHGAP32, ACAP1, PHACTR2, SMG7, SGSM2, DENND4B, ARHGAP25, SH2D3C, SH2D3A, UBA2, SAE1, RCAN2, RASGRP2 |
1809 | GO:0007264 | 0.00 | 1.44 | 74.07 | 94 | 259 | small GTPase mediated signal transduction | ABL1, ACTB, BIRC5, KLK3, TRIM23, ARF1, ARF4, ARF5, RND3, ARL1, ARL2, BUB1, BUB1B, KRIT1, CDC20, CDC25C, CDH1, CENPA, CENPE, CENPF, CTNNA1, CYBA, DIAPH1, DIAPH2, CTTN, CENPI, GEM, H3F3B, INCENP, KIF5A, KLK2, MAD2L1, RAB8A, MEN1, PPP1R12A, PPP1R12B, NUP98, PDPK1, RAB1A, RAB3A, RAB3B, RAB4A, RAB5A, RAB5B, RAB6A, RAB27A, RABIF, RAN, RANBP2, RANGAP1, RHEB, RPS27, CLIP1, SIAH2, SRF, WAS, YWHAH, YWHAZ, RND2, HIST1H4I, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, BCAR3, IQGAP1, HIST1H3F, DIRAS3, ZW10, BUB3, AURKB, RAB11B, RAB33A, RAB9A, RAB36, KNTC1, CKAP5, SH2D3C, SH2D3A, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, ARL4A, ARFRP1 |
1810 | GO:0080135 | 0.01 | 1.44 | 53.55 | 68 | 185 | regulation of cellular response to stress | ABL1, ACTL6A, APBB1, ARNTL, ATP6V0A1, BAX, BCL2L1, BMPR1A, BNIP3L, TSPO, CASP9, CD44, CD74, CDK6, CDKN2D, CEBPG, CHEK1, CLU, CSNK2A2, CTSK, DCN, DDX5, CTTN, KAT2A, GRINA, HIC1, HMGA1, ING2, KCNK2, KDR, MGMT, ATXN3, OPA1, PCNA, PIP4K2A, PPP4C, DNAJC3, PTPN2, RAD51, RPL28, SETMAR, SNAI1, SREBF1, TPT1, TSC1, UBE2V1, VDAC1, WFS1, ZBTB17, IFT88, CUL4A, OGT, RUVBL1, TP63, RNF8, USP14, ARHGEF2, TRIP12, RAB33A, EIF2AK3, ATG5, BRE, FEZ2, RUBCN, NUAK1, BCL2L11, FEM1B, TRIM28 |
1811 | GO:0007015 | 0.05 | 1.44 | 31.48 | 40 | 108 | actin filament organization | ABL1, ANG, ARF1, CAPG, CAV3, CTNNA1, DBN1, DIAPH1, DIAPH2, EMP2, CTTN, GHSR, GRB2, HCLS1, ICAM1, INPPL1, PRKCE, PRKCI, PROX1, RAC2, CCL21, SPTA1, SPTB, CLRN1, WAS, SORBS2, LATS1, ARHGEF2, SLIT2, PICK1, GMFG, BCAR1, WDR1, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, FRY, ABI2 |
1812 | GO:0048285 | 0.00 | 1.44 | 97.46 | 123 | 333 | organelle fission | ABL1, ACOX1, BIRC5, ATRX, BAX, BMP4, BRCA2, BRDT, BUB1, BUB1B, CCNB1, CCNF, CCNG2, CD28, CDK11B, CDC6, CDC20, CDC25A, CDC25C, CDC27, CDK2, CDK3, CENPE, CENPF, CHEK1, CLTC, CSNK2A1, CSNK2A2, DAPK3, DCN, DHODH, DRD3, DUSP1, E4F1, ENSA, ERCC4, FGF8, FGFR3, GEM, GOLGA2, GPR3, HGF, IGF1, IGF1R, IGF2, IL1A, INCENP, ING2, INS, KDR, KIF25, MAD2L1, MKI67, PPP1R12A, NUMA1, OPA1, CHMP1A, PPP2R1A, PPP5C, PRKAR1A, PTEN, PEX19, RAD21, RAD51, RAD51C, RAD51B, RAD51D, RAN, RB1, RBBP8, RPL24, RPS3, RPS6KA2, CLIP1, SMARCA4, DYNLT3, DYNLT1, TOP2A, TOP2B, TTK, UBB, UBE2D1, VRK1, XRCC2, ZNF207, NUP214, CLTCL1, USP9X, SMC1A, CUL3, FKBP6, RUVBL1, TNKS, CDC23, PEX11B, PEX11A, CDC16, RNF8, LATS1, SMC3, CCNB2, CTDP1, ARHGEF2, ZW10, BUB3, AURKB, KIF3B, RECQL5, BRE, MAD2L1BP, CEP57, KNTC1, DLGAP5, CKAP5, CUL7, KIAA0196, KLHL21, DCLRE1A, REC8, SMC4, ACTR3, ACTR2, RAD50 |
1813 | GO:0035966 | 0.05 | 1.43 | 30.73 | 39 | 105 | response to topologically incorrect protein | ADD1, ASNS, ATF3, ATF4, BAX, CLU, TPP1, CTH, DDX11, EP300, EXTL3, F12, HDGF, DNAJB2, HSPA4, HSPA6, HSPB1, HSPB2, IFNG, ATXN3, DNAJC3, PTPN2, SHC1, SULT1A3, HSP90B1, UFD1L, WFS1, ZBTB17, MANF, ATP6V0D1, VAPB, EIF2AK3, GOSR2, TATDN2, CUL7, MFN2, HDAC6, BCL2L11, CTDSP2 |
1814 | GO:0046483 | 0.00 | 1.43 | 894.34 | 1048 | 3068 | heterocycle metabolic process | ABCA1, ABCA2, ABL1, ACACB, ACPP, ACTN4, ACTL6A, ACTN1, ACVR1B, ACVR2B, ACVRL1, ADA, ADAM8, ADAR, ADCY1, ADCY7, ADCYAP1R1, ADSS, AEBP1, AES, AGTR2, NR0B1, AHCY, AHR, AK1, AK2, ALAD, ALAS2, ALK, ALX3, AMPD1, AMPD2, ANG, ANXA1, ANXA3, ANXA4, APAF1, APBB1, APBB2, XIAP, BIRC5, APP, APRT, AQP1, ARF4, PHOX2A, ARNTL, ASCL1, ASCL2, ATF3, ATF4, RERE, ATP1A2, ATP2B2, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V0A1, ATR, ATRX, AVPR2, BACH1, BAD, BARD1, BAX, BCHE, BCL3, BCL9, BICD1, PRDM1, BLVRA, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTK, BYSL, TSPO, CACNB4, CALM3, CAMK2A, CAT, RUNX2, CBL, CCNB1, CCNC, CCNE1, CCNT2, CD3D, CD28, CD86, TNFSF8, CD36, ENTPD2, CD40, CDA, CDK11B, CDC6, CDC25A, CDC25C, CDH1, CDK2, CDK5, CDK8, CDKN1A, CDKN2D, CDX2, CEBPE, CEBPG, CENPB, CENPF, CHD2, CHD4, CHEK1, CHUK, CLU, CLK1, CLK3, CLNS1A, CMKLR1, CNP, COL1A1, COX6A1, COX6B1, COX7B, COX7C, COX8A, COX15, CPOX, CPS1, CREB1, CRH, CRX, CRY2, CSF2, CSNK1D, CSNK2A1, CSNK2A2, CSTF3, CTGF, CTH, CTNS, CTNND1, CTNND2, CTRB1, CYP1A2, CYP2A6, CYP3A4, DAO, DAPK3, DARS, DBP, DCN, DDB1, DDX1, DDX3X, DDX5, DDX6, DHX8, DDX10, DDX11, DFFA, DFFB, DHFR, DHODH, DKC1, DLG2, DLG3, DLX5, SARDH, DNASE1, DNASE1L1, DNASE1L2, DNASE1L3, DNM2, DNMT1, TRDMT1, DNMT3A, DNMT3B, DNTT, DPEP1, DRD3, DRD5, ARID3A, ATN1, RCAN1, TSC22D3, DTX1, DUSP1, E2F5, E2F6, E4F1, EBF1, TYMP, ECM1, EDA, S1PR1, LPAR1, EDNRA, EDNRB, EFNA1, CELSR2, EGR2, EGR3, EGR4, EIF4A1, EIF4A2, EIF4B, EIF4E, ELAVL2, ELF1, ELF3, ELK1, ELK3, EMX1, EMX2, EN1, SLC29A1, EP300, EPHA5, EPRS, EYA4, ERCC3, ERCC4, ERCC6, ERF, ERG, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA2, EZH1, F2R, FANCE, PTK2B, FANCB, FANCF, FANCG, FAU, FBN1, EFEMP1, FEN1, FGF4, FGF7, FGF8, FGF9, FGFR3, FOXD1, FLII, AFF2, FSHB, FSHR, NR5A2, FUT8, FZD2, G6PC, GALR1, GARS, GATA3, GATA4, GATA6, GCG, KAT2A, GDF9, GDNF, GHRHR, GIF, GPC3, GLO1, GMDS, GNAI3, GNAS, GOT2, GPX1, GPX2, GRIN2A, GSC2, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GUK1, GUCY2D, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, H3F3B, HARS, HAS3, HBE1, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIP1, HIVEP2, HLF, HLCS, HMBS, HMGN1, HMGCR, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HNMT, HNRNPC, HOXC10, HOXC11, HOXD4, HOXD8, HOXD9, HOXD10, HOXD12, HPN, HPRT1, HPX, PRMT1, HSBP1, HSF4, HTR2C, ICAM1, ID1, ID2, IFI16, SP110, IFNA2, IFNG, IGF1R, IGF2, RBPJ, IHH, IL1A, IL3, IL10, ILK, IMPDH1, IMPDH2, IDO1, ING2, INSIG1, EIF3E, IRAK1, ITGA6, IRAK2, IRF1, IRF5, ISG20, ISL1, JARID2, JUN, JUNB, JUND, JUP, KCNK2, KCNQ1, KIT, KPNA1, KPNA2, LDHC, LMO1, LTF, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MEN1, MEOX2, KITLG, MGMT, CIITA, ATXN3, MKI67, AFF1, FOXO4, NUDT1, PPP1R12A, DRG1, TONSL, CNOT2, CNOT4, NRF1, YBX1, NTHL1, NTRK2, NTRK3, DDR2, NUP98, NVL, OAS1, OAS3, OAT, ORC1, ORC2, ORC4, OTX1, OTX2, OVOL1, P2RY11, P4HA1, PA2G4, PRDX1, PAH, SERPINE1, PALM, PAM, PAX2, PAX3, PAX9, PCBP2, PCK1, PCNA, CHMP1A, PDE4B, PDE8A, PDPK1, PEG3, PFAS, PGR, PHB, PHF2, PIM1, EXOSC9, PPID, PPP1R8, PPP2R1A, PPP2R2A, PPP4C, PPP5C, PRIM2, PRKAB2, PRKAR1A, PRKCB, PRKCI, PRKD1, PRKCQ, MAPK1, MAPK3, PROX1, PRPS2, PRPSAP1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD9, PTAFR, PTCH1, PTEN, PTGDR, PTH, PTMA, PTMS, PTPN14, PURA, PURB, ABCD4, PYCR1, QARS, QDPR, RAC1, RAD21, RAD23B, RAD51, RAD51C, RAD51B, RAD51D, RAF1, RAG1, RAG2, RAN, RANBP2, RARA, RARB, RB1, RBBP4, RBBP6, RBBP8, RBL2, RBM4, RBMS1, RBMS2, RCVRN, UPF1, DPF2, REST, RET, REV3L, RFC1, RFC3, RFC4, RFC5, RFX1, RFX3, RFX4, RFXAP, RGS12, RHEB, RLF, RNASE1, RNASE2, RNASE3, RNASE6, RNF2, RNF6, RP9, RPA2, RPA3, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS6KA1, RPS6KA3, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, RRM1, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A11, S100A12, SALL1, SATB1, ATXN7, XCL1, SDHC, TRAPPC2, SET, SETMAR, SFPQ, SFRP5, SRSF1, SRSF5, SRSF7, SFSWAP, TRA2B, SGK1, SHC1, SHMT1, SHMT2, SIAH2, SIM2, SIX3, SLC9A1, SLC34A1, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCD3, SMARCE1, SUMO3, SNAI1, SNAPC3, SNAPC4, SNCA, SNRNP70, SNRPA, SNRPA1, SNRPC, SNRPD1, SNRPE, SNRPF, SOD2, SOX3, SOX4, SOX5, SOX9, SOX10, SOX11, SP1, SP2, SP3, SP100, UAP1, SPIB, SPTA1, SPTB, SRD5A1, SREBF1, SRF, SRPK2, SRY, TRIM21, SSRP1, STAT2, STAT4, STAT5B, STAT6, SULT1E1, SULT1A3, SULT1C2, SULT2B1, SUPV3L1, SYK, T, TAF4B, TAF7, TAF10, TAL1, TARBP1, TARBP2, TAZ, TBL1X, TBP, HNF1A, GCFC2, ZNF354A, PRDX2, NR2F1, NR2F2, KLF10, NR2E1, TMPO, TNFRSF1A, TNNI2, TOP1, TOP2A, TOP2B, TP73, TPMT, NR2C1, NR2C2, TRAF1, TRAF2, TRH, TRIP6, TRPS1, TSN, TSC1, TSG101, TTF1, TULP3, TNFSF4, TYMS, UBB, UBA7, UBE2D1, UBE2D2, UBE2L3, UBE2V1, UBE3A, SUMO1, UCP1, UFD1L, SCGB1A1, UNG, USP4, NR1H2, UPP1, UQCRC1, UQCRC2, UQCRH, UROS, USF1, UVRAG, VAV1, VDR, VEGFA, VIP, VIPR2, WFS1, WNT1, WNT11, WRN, XPA, XRCC2, XRCC5, YY1, YWHAH, YWHAZ, ZFP37, ZFPL1, ZFX, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF33B, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF221, ZNF91, ZNF99, ZNF124, ZNF131, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF208, ZNF214, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZP3, ZXDA, PRDM2, LRP8, FZD5, AIMP2, MAFK, ARHGEF5, NUP214, FOSL1, FGF23, AAAS, CDK2AP1, ANP32A, SF3A2, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, RBM10, KDM5C, SMC1A, USP9Y, ARID1A, HIST1H4I, PICALM, CDC45, EOMES, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NR0B2, UTF1, DUSP11, CUL4A, CUL3, CUL2, TTF2, KLF11, SMARCA5, FKBP6, PARG, IKBKG, IKBKAP, HAT1, GAS7, CYP4F2, COPS3, PIR, FCN3, BLZF1, CDC14B, PRPF18, RRP1, KHSRP, PRKRA, STK16, RGS20, RUVBL1, KLF7, TP63, RNASET2, CHRD, DDX3Y, PDE5A, DYNLL1, TNKS, ALDH4A1, SRSF9, TRADD, EED, RIPK1, TNFSF13, RIPK2, SUCLG1, CREG1, SAP30, HESX1, ALKBH1, PER3, VNN2, VNN1, SLC5A6, TAX1BP1, BUD31, HERC2, PHOX2B, MBD4, FUBP3, HIST1H3F, HIST1H2AG, P4HA2, RPS6KA4, TNFSF18, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, RPL14, PAPSS1, DIRAS3, USP2, RGN, PDLIM1, SMC3, PRPF3, CBFA2T2, DYRK1B, CTDP1, EXO1, SCAF11, ARHGEF2, DDX21, BMP15, AURKB, VAPB, CCPG1, RPS6KA5, ITGB1BP1, ZNF235, KLF4, COPS2, TRIP12, TRIP11, HMGN3, TRIP4, GTF3C5, GTF3C4, GTF3C3, EFTUD2, RPL23, COX5A, RECQL5, ZRANB2, SNRNP40, DDX23, HAND1, ZNF264, EIF2AK3, FHL5, PICK1, IL27RA, AKAP6, ATG5, ONECUT2, LITAF, TBPL1, ZNF254, CIR1, CHD1L, GTPBP1, GABBR2, NR1D1, CLOCK, BRE, SOX13, ENTPD4, RBM39, CREB5, AKAP12, RNF14, GUCA1C, NUP155, PPM1F, ZNF516, SAFB2, PHF14, KDM4A, VGLL4, NUP93, BZW1, KIAA0391, DHX34, ST18, UTP14C, ZNF646, VPRBP, USP34, SETD1A, ZNF536, ZFYVE16, EIF4A3, DHX38, TATDN2, RNF40, RB1CC1, ARHGEF11, GINS1, ZEB2, ZBTB24, ZNF518A, SMG7, RNF10, ZBTB5, DCLRE1A, RBM8A, USP3, NR1I3, NR1H4, NR1D2, RBX1, REC8, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, GNE, PARP3, ABCB6, PDCD7, PQBP1, RAD50, ZNF263, YAF2, G3BP1, SUGP2, TRIM28, SLC25A13, ZNF197, ZNF256, ALYREF, RNF41, PSMD14, OLIG2, DENND4A, IRX5, RAMP3 |
1815 | GO:0051252 | 0.00 | 1.43 | 570.39 | 689 | 1949 | regulation of RNA metabolic process | ABCA2, ABL1, ACTN4, ACTL6A, ACTN1, ACVR1B, ACVR2B, ACVRL1, ADAM8, AEBP1, AES, AGTR2, NR0B1, AHR, ALK, ALX3, ANXA3, ANXA4, APBB1, APBB2, XIAP, BIRC5, APP, ARF4, PHOX2A, ARNT, ARNTL, ASCL1, ASCL2, ATF3, ATF4, RERE, ATRX, BACH1, BARD1, BCL3, BCL9, PRDM1, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTK, CAMK2A, CAT, RUNX2, CBL, CCNB1, CCNC, CCNE1, CCNT2, CD3D, CD28, CD86, TNFSF8, CD36, CD40, CDK11B, CDC6, CDH1, CDK2, CDK5, CDK8, CDX2, CEBPE, CEBPG, CENPB, CENPF, CHD2, CHD4, CHEK1, CHUK, CLU, CLK1, CLK3, CMKLR1, COL1A1, CREB1, CRX, CRY2, CSNK2A1, CSNK2A2, CTH, CTNND1, CTNND2, DAPK3, DBP, DCN, DDX1, DDX3X, DDX5, DHFR, DLX5, DNM2, DNMT1, DNMT3A, DNMT3B, DRD3, ARID3A, ATN1, RCAN1, TSC22D3, DTX1, E2F5, E2F6, E4F1, EBF1, ECM1, EDA, S1PR1, EDNRB, EFNA1, CELSR2, EGR2, EGR3, EGR4, EIF4A2, ELAVL2, ELF1, ELF3, ELK1, ELK3, EMX1, EMX2, EN1, EP300, EPHA5, EYA4, ERCC3, ERCC6, ERF, ERG, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA2, EZH1, F2R, FBN1, EFEMP1, FGF4, FGF7, FGF8, FGF9, FGFR3, FOXD1, FLII, AFF2, FSHB, NR5A2, FZD2, GALR1, GATA3, GATA4, GATA6, GCG, KAT2A, GDF9, GDNF, GPC3, GLO1, GSC2, GTF2I, GTF3A, BRF1, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, H3F3B, HAS3, HBE1, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIP1, HIVEP2, HLF, HMGN1, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD4, HOXD8, HOXD9, HOXD10, HOXD12, HPN, PRMT1, HSBP1, HSF4, ICAM1, ID1, ID2, IFI16, SP110, IFNA2, IFNG, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL10, ILK, ING2, INS, INSIG1, IRAK1, ITGA6, IRAK2, IRF1, IRF5, ISL1, JARID2, JUN, JUNB, JUND, JUP, KIT, LMO1, LTF, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MEN1, MEOX2, CIITA, ATXN3, AFF1, FOXO4, PPP1R12A, TONSL, CNOT2, NRF1, YBX1, NTRK3, DDR2, OAS1, OAS3, ORC1, ORC2, OTX1, OTX2, OVOL1, PA2G4, SERPINE1, PAM, PAX2, PAX3, PAX9, PCK1, PCNA, CHMP1A, PDE8A, PDPK1, PEG3, PGR, PHB, PHF2, PIM1, PPID, PPP1R8, PPP2R1A, PRKAA1, PRKAR1A, PRKCB, PRKCI, PRKD1, PRKCQ, MAPK1, MAPK3, PROX1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD9, PTAFR, PTCH1, PTEN, PTGIS, PTH, PTPN14, PURA, PURB, RAD21, RAF1, RAN, RARA, RARB, RB1, RBBP4, RBBP8, RBL2, RBM4, UPF1, DPF2, REST, RET, RFC1, RFX1, RFX3, RFX4, RFXAP, RLF, RNF2, RNF6, RPL6, RPS3, RPS6KA1, RPS6KA3, RPS26, RPS27A, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A12, SALL1, SATB1, ATXN7, XCL1, TRAPPC2, SET, SFPQ, SFRP5, SRSF7, SFSWAP, TRA2B, SGK1, SIAH2, SIM2, SIX3, SLC9A1, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCD3, SMARCE1, SNAI1, SNAPC3, SNAPC4, SNCA, SNRNP70, SOD2, SOX3, SOX4, SOX5, SOX9, SOX10, SOX11, SP1, SP2, SP3, SP100, SPIB, SREBF1, SRF, SRPK2, SRY, TRIM21, SSRP1, STAT2, STAT3, STAT4, STAT5B, STAT6, SUPV3L1, SYK, T, TAF4B, TAF7, TAF10, TAL1, TARBP1, TARBP2, TBL1X, TBP, HNF1A, GCFC2, ZNF354A, NR2F1, NR2F2, KLF10, NR2E1, TMPO, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TRPS1, TSG101, TTF1, TULP3, TNFSF4, TYMS, UBB, UBE2D1, UBE2D2, UBE2L3, UBE2V1, UBE3A, SUMO1, UCP1, SCGB1A1, NR1H2, USF1, VAV1, VDR, VEGFA, WFS1, WNT1, WNT11, XRCC5, YY1, YWHAH, ZFP37, ZFPL1, ZFX, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF33B, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF221, ZNF91, ZNF99, ZNF124, ZNF131, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF208, ZNF214, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZP3, ZXDA, PRDM2, LRP8, FZD5, MAFK, ARHGEF5, FOSL1, FGF23, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, USP9Y, ARID1A, HIST1H4I, PICALM, CDC45, EOMES, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NR0B2, UTF1, CUL3, CUL2, TTF2, KLF11, SMARCA5, OGT, IKBKG, IKBKAP, HAT1, GAS7, PIR, FCN3, BLZF1, KHSRP, STK16, RGS20, RUVBL1, KLF7, TP63, CHRD, DYNLL1, TNKS, SRSF9, TRADD, EED, RIPK1, RIPK2, CREG1, SAP30, HESX1, PER3, TAX1BP1, BUD31, PHOX2B, FUBP3, HIST1H3F, HIST1H2AG, RPS6KA4, TNFSF18, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, USP2, RGN, PDLIM1, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, BMP15, AURKB, CCPG1, RPS6KA5, ITGB1BP1, ZNF235, KLF4, COPS2, TRIP11, HMGN3, TRIP4, RECQL5, ZRANB2, HAND1, ZNF264, EIF2AK3, FHL5, ONECUT2, LITAF, TBPL1, ZNF254, CIR1, GTPBP1, NR1D1, CLOCK, SOX13, RBM39, CREB5, RNF14, PPM1F, ZNF516, SAFB2, PHF14, KDM4A, VGLL4, BZW1, DHX34, ST18, ZNF646, VPRBP, USP34, SETD1A, ZNF536, ZFYVE16, RNF40, RB1CC1, ARHGEF11, ZEB2, ZBTB24, ZNF518A, RNF10, ZBTB5, RBM8A, NR1I3, NR1H4, NR1D2, RBX1, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, PQBP1, ZNF263, YAF2, TRIM28, ZNF197, ZNF256, ALYREF, RNF41, OLIG2, DENND4A, IRX5, RAMP3 |
1816 | GO:0044763 | 0.00 | 1.43 | 198.05 | 239 | 1008 | single-organism cellular process | ABCA2, ABCA3, ABCB7, ABO, ACTA2, ADD3, ALAD, ALAS2, ANPEP, ANXA11, AQP5, AQP6, PHOX2A, ART1, ASCL2, ATP2B3, ATP4B, BFSP1, BLVRA, BPI, ZFP36L2, BYSL, CA1, CA4, CA6, CACNG1, CAPN6, CDH7, CDH9, CDH10, CDH12, CDH15, CD52, CDX2, CEBPE, CHD2, TBCB, CLCA1, CLCN2, CLCN7, CLCNKA, CLCNKB, CLN5, CLNS1A, COX7A1, CPOX, CRX, CRYGB, CSRP1, CSRP2, CYLC1, CYLC2, DAZ1, DDX6, COCH, DHCR7, DKC1, DNASE1L2, DPH2, EIF2B1, ELAVL1, ELAVL3, ELF3, EN1, ERF, ESD, ETS2, ETV3, ETV6, EVPL, EVX1, EZH1, FBLN2, FTL, FUT6, GIF, GOLGB1, GP9, HIST1H1B, HLF, HMBS, HMX2, HNRNPC, HOXC10, HOXD4, HOXD9, HOXD10, HSBP1, DNAJB2, ICAM4, IREB2, IVL, JARID2, KRT4, KRT5, KRT9, KRT14, LIM2, LMO1, MATN3, MFAP3, MGAT2, ODF1, REG3A, PEX1, PEX6, PEX10, PEX12, CFP, FXYD3, EXOSC9, PPIB, PPP1R7, PRM2, KLK10, PTPN3, PTPRS, PURA, PURB, ABCD4, RAG2, RBL2, RNF2, RTN2, SCNN1A, SCNN1G, SCO1, SRSF5, SGCB, SGCD, SIM2, SLC2A4, SLC2A5, SLC4A1, SLC5A2, SLC6A7, SLC7A1, SLC9A2, SLC9A3, SLC12A2, SLC13A1, SLC15A1, SLC20A2, SLCO2A1, SLC22A1, SMARCA1, SMARCA2, SOX3, SOX5, SP3, SPIB, SPRR2A, SPRR2D, SPRR2E, SPRR2G, SPRR3, SRY, ST14, TACC1, TAF4B, TAF10, TAL1, TBCD, TPBG, TPD52, TSPY1, TTC3, TUFM, UPK2, UPK3A, VBP1, ZNF3, ZNF91, VEZF1, SLC30A2, PRDM2, RNF103, TUSC3, CDK2AP1, SLC14A2, SLC10A3, BAP1, EOMES, GFI1B, TAGLN2, PIR, DDX3Y, GALNT4, B3GALT2, EED, RIOK3, SCEL, CDKL1, SAP30, EIF2B3, EIF2S2, AP1M1, MGAM, SLC13A2, CLDN12, CLDN6, CLDN1, USP2, SLC16A6, SLC16A5, DYRK1B, DDX21, ZMYM6, CCPG1, PTER, GTF3C5, GTF3C4, SLC22A8, COG1, SLC22A14, HAND1, ADAMTS2, SOX13, KIAA0391, UTP14C, VPRBP, SETD1A, FAM65B, FRMPD4, PIEZO1, RNF40, SPATA2, ZBTB24, CEP350, SV2B, ATP2C2, DMTF1, AP1M2, SAE1, ABCC5, ABCB6, ALYREF, SLC35B1, IRX5 |
1817 | GO:1903506 | 0.00 | 1.43 | 549.91 | 665 | 1879 | regulation of nucleic acid-templated transcription | ABCA2, ABL1, ACTN4, ACTL6A, ACTN1, ACVR1B, ACVR2B, ACVRL1, ADAM8, AEBP1, AES, AGTR2, NR0B1, AHR, ALK, ALX3, ANXA3, ANXA4, APBB1, APBB2, XIAP, BIRC5, APP, ARF4, PHOX2A, ARNT, ARNTL, ASCL1, ASCL2, ATF3, ATF4, RERE, ATRX, BACH1, BCL3, BCL9, PRDM1, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BMPR2, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTK, CAMK2A, CAT, RUNX2, CBL, CCNC, CCNE1, CCNT2, CD3D, CD28, CD86, TNFSF8, CD36, CD40, CDK11B, CDC6, CDH1, CDK2, CDK5, CDK8, CDX2, CEBPE, CEBPG, CENPB, CENPF, CHD2, CHD4, CHEK1, CHUK, CLU, CMKLR1, COL1A1, CREB1, CRX, CRY2, CSNK2A1, CSNK2A2, CTH, CTNND1, CTNND2, DAPK3, DBP, DCN, DDX1, DDX3X, DDX5, DHFR, DLX5, DNM2, DNMT1, DNMT3A, DNMT3B, DRD3, ARID3A, ATN1, RCAN1, TSC22D3, DTX1, E2F5, E2F6, E4F1, EBF1, ECM1, EDA, S1PR1, EDNRB, EFNA1, CELSR2, EGR2, EGR3, EGR4, EIF4A2, ELAVL2, ELF1, ELF3, ELK1, ELK3, EMX1, EMX2, EN1, EP300, EPHA5, EYA4, ERCC3, ERCC6, ERF, ERG, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA2, EZH1, F2R, FBN1, EFEMP1, FGF4, FGF7, FGF8, FGF9, FGFR3, FOXD1, FLII, FSHB, NR5A2, FZD2, GALR1, GATA3, GATA4, GATA6, GCG, KAT2A, GDF9, GDNF, GPC3, GLO1, GSC2, GTF2I, GTF3A, BRF1, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, H3F3B, HAS3, HBE1, HCLS1, HDGF, HEXB, HGF, NRG1, HHEX, HIC1, HIP1, HIVEP2, HLF, HMGN1, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD4, HOXD8, HOXD9, HOXD10, HOXD12, PRMT1, HSBP1, HSF4, ICAM1, ID1, ID2, IFI16, SP110, IFNA2, IFNG, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL10, ILK, ING2, INS, INSIG1, IRAK1, ITGA6, IRAK2, IRF1, IRF5, ISL1, JARID2, JUN, JUNB, JUND, JUP, KIT, LMO1, LTF, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MEN1, MEOX2, CIITA, ATXN3, AFF1, FOXO4, PPP1R12A, TONSL, CNOT2, NRF1, YBX1, NTRK3, DDR2, ORC1, ORC2, OTX1, OTX2, OVOL1, PA2G4, SERPINE1, PAM, PAX2, PAX3, PAX9, PCK1, PCNA, CHMP1A, PDE8A, PDPK1, PEG3, PGR, PHB, PHF2, PIM1, PPID, PPP1R8, PPP2R1A, PRKAA1, PRKAR1A, PRKCB, PRKCI, PRKD1, PRKCQ, MAPK1, MAPK3, PROX1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD9, PTAFR, PTCH1, PTEN, PTGIS, PTH, PTPN14, PURA, PURB, RAD21, RAF1, RAN, RARA, RARB, RB1, RBBP4, RBBP8, RBL2, DPF2, REST, RET, RFC1, RFX1, RFX3, RFX4, RFXAP, RLF, RNF2, RNF6, RPL6, RPS3, RPS6KA1, RPS6KA3, RPS27A, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A12, SALL1, SATB1, ATXN7, XCL1, TRAPPC2, SET, SFPQ, SFRP5, SFSWAP, SGK1, SIAH2, SIM2, SIX3, SLC9A1, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCD3, SMARCE1, SNAI1, SNAPC3, SNAPC4, SNCA, SOD2, SOX3, SOX4, SOX5, SOX9, SOX10, SOX11, SP1, SP2, SP3, SP100, SPIB, SREBF1, SRF, SRY, TRIM21, SSRP1, STAT2, STAT3, STAT4, STAT5B, STAT6, SYK, T, TAF4B, TAF7, TAF10, TAL1, TARBP1, TBL1X, TBP, HNF1A, GCFC2, ZNF354A, NR2F1, NR2F2, KLF10, NR2E1, TMPO, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TRPS1, TSG101, TTF1, TULP3, TNFSF4, TYMS, UBB, UBE2D1, UBE2D2, UBE2L3, UBE2V1, UBE3A, SUMO1, UCP1, SCGB1A1, NR1H2, USF1, VAV1, VDR, VEGFA, WFS1, WNT1, WNT11, XRCC5, YY1, YWHAH, ZFP37, ZFPL1, ZFX, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF33B, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF221, ZNF91, ZNF99, ZNF124, ZNF131, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF208, ZNF214, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZP3, ZXDA, PRDM2, LRP8, FZD5, MAFK, ARHGEF5, FOSL1, FGF23, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, USP9Y, ARID1A, HIST1H4I, PICALM, CDC45, EOMES, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NR0B2, UTF1, CUL3, CUL2, TTF2, KLF11, SMARCA5, OGT, IKBKG, IKBKAP, HAT1, GAS7, PIR, BLZF1, KHSRP, STK16, RGS20, RUVBL1, KLF7, TP63, CHRD, DYNLL1, TNKS, TRADD, EED, RIPK1, RIPK2, CREG1, SAP30, HESX1, PER3, TAX1BP1, BUD31, PHOX2B, FUBP3, HIST1H3F, HIST1H2AG, RPS6KA4, TNFSF18, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, USP2, PDLIM1, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, BMP15, AURKB, CCPG1, RPS6KA5, ITGB1BP1, ZNF235, KLF4, COPS2, TRIP11, HMGN3, TRIP4, RECQL5, ZRANB2, HAND1, ZNF264, EIF2AK3, FHL5, ONECUT2, LITAF, TBPL1, ZNF254, CIR1, NR1D1, CLOCK, SOX13, RBM39, CREB5, RNF14, PPM1F, ZNF516, SAFB2, PHF14, KDM4A, VGLL4, BZW1, ST18, ZNF646, VPRBP, USP34, SETD1A, ZNF536, ZFYVE16, RB1CC1, ARHGEF11, ZEB2, ZBTB24, ZNF518A, RNF10, ZBTB5, NR1I3, NR1H4, NR1D2, RBX1, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, PQBP1, ZNF263, YAF2, TRIM28, ZNF197, ZNF256, ALYREF, RNF41, OLIG2, DENND4A, IRX5, RAMP3 |
1818 | GO:0005975 | 0.00 | 1.43 | 159.21 | 199 | 544 | carbohydrate metabolic process | ABO, ACACB, ADCYAP1R1, ADRA1B, ALDH1B1, ALDOC, ARCN1, ARF4, ARNT, ART1, ATF3, ATF4, BAD, BPGM, CACNA1A, CALM3, CANX, CD44, CD59, CLN5, CLTC, COPA, COPB1, CPS1, CSNK1D, VCAN, CSPG4, SLC25A10, CYB5A, DAD1, CD55, DCN, CYB5R3, DYNC1H1, ENO2, EXT2, EXTL1, PTK2B, GPC4, GPC5, FUT6, FUT8, G6PC, GAA, GALC, GALE, GALK2, GALNS, GAPDH, GCG, GCGR, KAT2A, B4GALT1, GK2, GPC3, GLO1, GM2A, GMDS, GOLGA2, GOLGB1, GOT2, GPC1, GPD2, GPI, GPLD1, GRIA1, GYS2, HAS1, HAS2, HAS3, HEXA, HEXB, HK2, FOXA2, ONECUT1, HRH1, IDH1, IDH3A, IDS, IDUA, IGF1, IGF2, IGFBP3, INPP1, INS, INPPL1, KCNJ11, LDHC, MAN2B1, MDH2, MGAT2, MGAT3, NTSR1, NUP98, OAS1, OMD, OGDH, OVGP1, P2RX7, PCK1, PCK2, PDK4, CFP, PFKFB4, PGAM1, PGD, PGK2, PHKA2, PHKB, PHKG1, PPP1CA, PPP1R3C, PPP2R5D, PPP6C, PRKAA1, PRKACB, PRKACG, PRKAG1, PRKCE, PRKCSH, PTAFR, PTEN, PTH, PTPN2, PYGB, PYGM, RAB1A, RANBP2, RPE, RPS27A, SDC1, SDC4, TRAPPC2, SLC2A2, SLC2A3, SLC2A4, SLC2A5, SLC5A2, SLC9A1, SNCA, SORD, UAP1, SPAM1, SPTA1, SPTB, STAT3, UBB, UGT2B7, UGT8, USF1, VEGFB, TUSC3, NUP214, AAAS, DYRK2, OGT, PARG, SLC25A12, USO1, DYNLL1, TNKS, GALNT4, B4GALT4, B4GALT3, B3GALT2, DPM2, SYNJ1, MGAM, STBD1, PAPSS1, RGN, COPB2, B4GALT6, KL, COG1, GSTO1, CHST3, MPDU1, GOSR1, TMEM59, SEC22B, GOSR2, NR1D1, NUP155, HS2ST1, SDC3, PPIP5K1, NUP93, EPM2AIP1, XYLB, HS3ST3B1, HS3ST1, NR1H4, GNE, PARP3, ABCC5, UST, CHST4, SLC25A13 |
1819 | GO:0070727 | 0.00 | 1.43 | 266.61 | 330 | 911 | cellular macromolecule localization | ABL2, ACTL6A, ADAR, AP2B1, AGTR2, ANGPT1, ARCN1, ARF4, ARL1, ARL2, ARNTL, RERE, ATR, ATRX, BAD, BARD1, BAX, BBS4, BCL2L1, BCL3, BICD1, BMP4, BMPR1A, BNIP3L, BRCA2, BSG, BUB1B, TSPO, CACNA1A, CACNB1, CASP8, CAV3, CBLB, CCNB1, CD4, CD36, SCARB2, CD63, CD74, CDH1, CDK5, CDKN1A, CENPA, CHRM1, AP2M1, AP1S1, AP2S1, CLTC, COL1A1, COPA, COPB1, CSE1L, CSNK1D, CSNK2A2, CTNNA1, CTSK, DBN1, DDX1, DDX3X, DIAPH1, DKC1, DLG2, DLG3, DPP6, EDA, EGR2, EPHA2, EIF5A, EMD, EMP2, CTTN, ETV5, F2R, FAU, FGF7, FGF9, FLOT2, FNTA, FYB, FYN, GAS8, KAT2A, GDI1, GFER, GLRB, GNAQ, GOLGA4, GPM6B, GPR26, GRID2, HIST1H1B, HCLS1, NRG1, HHEX, HK2, HNMT, HSPA4, HSPA9, ID1, IFIT1, IFNG, IGF1, IL10, IL12B, IL18, INS, ITGA4, ITGAL, ITGB1, JUN, JUP, KCNA1, KPNA1, KPNA2, KPNA3, KPNA4, IPO5, LTBP2, SMAD3, SMAD7, RAB8A, NUBP1, TONSL, YBX1, NUP98, OAZ1, OAZ2, PRDX1, PALM, PCM1, PDPK1, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PPM1B, PRKCI, PRKCQ, MAPK1, MAPK3, PSMB7, PSMD8, PTCH1, PTGS2, PTN, PTPN14, PEX19, PEX5, RAB6A, RAB27A, RAC1, RAC2, RAD21, RAN, RANBP2, RANGAP1, RAP2A, RB1, RNASE2, RPGR, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, CLIP1, RTN2, RYR2, SFRP5, STIL, SIX3, SLC9A1, SLC12A1, SUMO3, SNX2, SORL1, SOX4, SOX9, SP100, SPAG4, SREBF1, SRP9, SRP14, SSR3, STAT3, STAU1, STYX, SYK, CNTN2, DYNLT1, TNFAIP2, TNFRSF1A, HSP90B1, TRIP6, TRPS1, TULP1, TULP2, TULP3, UBE2L3, SUMO1, UFD1L, UGT8, USP4, VCL, VEGFA, VIL1, WNT11, WRB, YWHAH, YWHAZ, ZIC1, ZBTB17, ZP3, FZD5, NUP214, AP3B2, AKAP1, MADCAM1, CLTCL1, BAP1, FZD7, DYRK2, OGT, CNTNAP1, KCNAB2, AP3B1, BLZF1, PRPF18, RGS20, RUVBL1, USO1, SSNA1, AKR1C3, NUMB, DYNLL1, TNKS, VAMP8, STX11, TNFSF14, IL18R1, LIN7A, NRP1, AP1M1, HERC2, AP3D1, CDKL2, RPL14, LATS1, ARHGEF2, RASSF9, ZW10, AURKB, VAPA, RAB11B, ITGB1BP1, COPB2, TRIP11, RPL23, SLC9A3R1, ZFYVE9, NRXN1, NRXN2, PEX16, EIF2AK3, PICK1, AKAP6, CABP1, LITAF, TMEM59, BAG4, AKAP12, NUP155, IPO13, NUP93, RAPGEF2, CROCC, RIMS2, CEP57, IFT140, ZFYVE16, ATG13, SNX17, SPCS2, TOMM20, C2CD5, KLHL21, FAM20B, MFN2, HDAC6, PDCD6, BCL2L11, PIGK, PARP3, TOM1, AP1M2, SAE1, PTPRU, ARFRP1, TRIM28, NUTF2, STX6, STAM2, RAMP3 |
1820 | GO:0065008 | 0.00 | 1.42 | 126.90 | 160 | 488 | regulation of biological quality | ADGRB2, BCL2L1, BCR, BNIP3L, ZFP36L2, CAMK2A, CASP8, CDC20, CHAT, CHRNB2, CHRNB4, CIRBP, CNGA1, CNGA2, CNP, CTNND2, CX3CR1, DAPK3, DBI, COCH, DPP6, DSC3, EGR2, EIF4EBP2, ELAVL1, EP300, EPHB1, EPHB3, ETV5, EYA2, FGD1, FLOT2, GAD1, GAPDH, GAS2, KAT2A, GDNF, GFAP, GLRA1, GLRB, GPM6B, GPR26, GRIA1, GRID2, GRIN2A, HIST1H1B, ID1, ITGA7, JUN, KCND2, KCND3, KCNK2, KPNA1, KPNA2, KPNA3, KPNA4, SMAD3, RAB8A, YBX1, NTRK2, NUP98, PAH, PALM, PEX6, PHB, SERPINB9, EXOSC9, SEPT5, PPIB, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD11, PTN, PTPRJ, PEX19, PYCR1, RAB3A, RARA, RPS27A, RXRA, S100A12, S100A13, SCN1A, SCN2A, SCN8A, SET, SLC1A6, SLC6A13, SLC22A3, TRIM21, SYN1, SYP, SYT1, SYT4, NR2E1, TNFRSF1B, TNNC1, TPBG, TYMS, SUMO1, SCGB1A1, USP4, YWHAH, ZNF207, NUP214, AAAS, ANP32A, SYN3, CNTNAP1, GAS7, KHSRP, DYNLL1, STX11, TNFSF13, DPM2, LIN7A, SYNJ1, USP2, VAPA, SNAP29, RAB9A, NRXN3, NRXN2, AKAP7, PSMF1, BAG3, RIN1, SNCAIP, NUP155, NUP93, RAPGEF2, PUM1, FRMPD4, EIF4A3, PIEZO1, RIMS3, USP3, HDAC6, ATP9A, KCNK7, PSME3, PSMD14 |
1821 | GO:0016050 | 0.02 | 1.42 | 53.26 | 67 | 182 | vesicle organization | ABCA1, AP2B1, ANXA1, AQP1, ARCN1, ARF1, CD59, AP2S1, CLCN3, COPA, COPB1, CREB1, CSNK1D, EPS15, F2R, GNAI3, GOLGA2, GRIA1, HIP1, INSIG1, RAB8A, P2RX7, CHMP1A, PIK3C2A, PPP6C, PRKCI, PTPRN, RAB1A, RAB3A, SORT1, SDC1, SDC4, TRAPPC2, SLAMF1, SNAP25, SNX2, SYP, SYT1, SYT4, TSG101, UVRAG, DYSF, PICALM, EEA1, CUL3, AP3B1, USO1, VAMP8, STX11, SNAP23, AP1M1, AP3D1, SEC22C, VAPB, VAPA, COPB2, SNAP29, TBPL1, GOSR1, SEC22B, GOSR2, ZFYVE16, ZEB2, C2CD5, SNAP91, PDCD6IP, STX6 |
1822 | GO:0022411 | 0.00 | 1.41 | 86.24 | 108 | 298 | cellular component disassembly | ACTL6A, ANXA5, BNIP3L, TSPO, CAPG, CAPS, CCNB1, COX8A, CSNK2A2, EIF5A, EMD, CTTN, FANCF, FAU, GABRA5, KAT2A, GOLGA2, NRG1, HK2, HMGA1, KCNK3, NTHL1, NUP98, P2RX5, CHMP1A, PEX13, PGK2, PPP1CA, PRKCB, PRKG1, RANBP2, UPF1, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, SET, SGK1, SLCO1A2, SLC22A3, SMARCA4, SMARCC1, SMARCD3, SMARCE1, SNRPD1, SNRPF, SPTA1, SPTB, SREBF1, STAT2, NR2C2, UBB, VDAC1, VIL1, VRK1, ZBTB17, ZNF189, FZD5, NUP214, AAAS, CHAF1B, ARID1A, RUVBL1, SYNJ1, RPL14, CCNB2, ARHGEF2, AURKB, RPL23, CHST3, ATG5, NUP155, NUP93, ATG13, RIMS3, PHYHIP, TOMM20, DNAJC6, MFN2, WDR1, FGFBP1, HDAC6 |
1823 | GO:1901566 | 0.02 | 1.41 | 51.70 | 65 | 182 | organonitrogen compound biosynthetic process | ACADM, ALDH3A2, ANGPT1, ALDH7A1, CHAT, CHKA, CHKB, CKM, CLTC, VCAN, CSPG4, DCN, ESD, EXT2, EXTL1, EXTL3, GPC4, FGF7, GPC5, B4GALT1, GPC3, GPC1, GSTZ1, HAS1, HAS2, HAS3, HEXA, IDO1, LCAT, OAZ1, OAZ2, ODC1, OMD, P2RX1, P2RX7, PCYT1A, PRKAA1, PRKD1, QDPR, SAT1, SDC1, SDC4, SMPD1, SMS, TNFRSF1A, UGT8, NSMAF, B4GALT4, B4GALT3, SGPL1, KYNU, VAPB, VAPA, B4GALT6, GSTO1, CHST3, TBPL1, HS2ST1, SDC3, PTDSS1, HS3ST3B1, HS3ST1, ABCC5, COL4A3BP, UST |
1824 | GO:2000112 | 0.00 | 1.41 | 596.02 | 712 | 2042 | regulation of cellular macromolecule biosynthetic process | ABCA2, ABL1, ACTL6A, ACVR1B, ACVR2B, ADAM8, ADAR, AEBP1, AES, AGTR2, NR0B1, AHR, ALK, ALX3, ANG, ANXA3, ANXA4, APBB1, APBB2, XIAP, BIRC5, APP, ARF4, PHOX2A, ARNT, ARNTL, ASCL1, ASCL2, ATF3, ATF4, RERE, ATR, ATRX, BACH1, BCL3, BCL9, PRDM1, BMI1, BMP1, BMP3, BMP4, BMP8B, BMPR1A, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTK, CAMK2A, CAT, RUNX2, CBL, CCNC, CCNE1, CCNT2, CD3D, CD28, CD86, TNFSF8, CD36, CD40, CDK11B, CDC6, CDH1, CDK2, CDK4, CDK5, CDK8, CDX2, CEBPE, CEBPG, CENPB, CENPF, CHD2, CHD4, CHEK1, CHUK, CIRBP, CLU, CMKLR1, COL1A1, CREB1, CRX, CRY2, CSF2, CSNK2A1, CSNK2A2, CTH, CTNND1, CTNND2, DAPK3, DAZ1, DBP, DCN, DDX1, DDX3X, DDX5, DDX6, DHFR, DLX5, DNM2, DNMT1, DNMT3A, DNMT3B, DRD3, ARID3A, ATN1, RCAN1, TSC22D3, E2F5, E2F6, E4F1, EBF1, ECM1, EDA, S1PR1, EDNRB, EFNA1, CELSR2, EGR2, EGR3, EGR4, EIF2B1, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4EBP2, EIF4G2, EIF5, EIF5A, ELAVL2, ELAVL1, ELF1, ELF3, ELK1, ELK3, EMX1, EMX2, EN1, EP300, EPHA5, EPRS, EYA4, ERCC3, ERCC6, ERF, ERG, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA2, EZH1, F2R, FBN1, EFEMP1, FGF4, FGF7, FGF8, FGF9, FGFR3, FOXD1, FLII, FSHB, NR5A2, FZD2, GALR1, GAPDH, GATA3, GATA4, GATA6, GCG, KAT2A, GDF9, GDNF, GPC3, GLO1, GOLGA2, GRB7, GSC2, GTF2I, GTF3A, BRF1, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, H3F3B, HAS3, HBE1, HCLS1, HDGF, HEXB, NRG1, HHEX, HIC1, HIP1, HIVEP2, HLF, HMGN1, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HNRNPC, HOXC10, HOXC11, HOXD4, HOXD8, HOXD9, HOXD10, HOXD12, PRMT1, HSBP1, HSF4, HSPB1, ICAM1, ID1, ID2, IFI16, SP110, IFNA2, IFNG, IGF1, IGF1R, IGF2, RBPJ, IHH, IL1A, IL3, IL10, ILK, ING2, INS, INSIG1, EIF3E, IRAK1, ITGA6, IRAK2, IREB2, IRF1, IRF5, ISL1, ITGA2, JARID2, JUN, JUNB, JUND, JUP, KIT, LMO1, LTF, CAPRIN1, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MEOX2, KITLG, CIITA, ATXN3, AFF1, FOXO4, PPP1R12A, CNOT2, NRF1, YBX1, NTRK3, DDR2, ORC1, ORC2, OTX1, OTX2, OVOL1, PA2G4, SERPINE1, PAM, PAX2, PAX3, PAX9, PCK1, PCNA, CHMP1A, PDE8A, PDPK1, PEG3, PGR, PHB, PHF2, PIM1, PPID, PPP1CA, PPP1R8, PPP2R1A, PRKAA1, PRKAR1A, PRKCB, PRKCI, PRKD1, DNAJC3, PROX1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD9, PTAFR, PTCH1, PTEN, PTGIS, PTH, PTPN14, PURA, PURB, RAC1, RAD21, RAF1, RAN, RARA, RARB, RB1, RBBP4, RBBP6, RBBP8, RBL2, RBM4, UPF1, DPF2, REST, RET, RFC1, RFX1, RFX3, RFX4, RFXAP, RLF, RNF2, RNF6, RPL6, RPL38, RPS3, RPS6KA1, RPS6KA3, RPS6KB1, RPS6KB2, RPS27A, RRM2, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A11, S100A12, SALL1, SATB1, ATXN7, CCL21, XCL1, TRAPPC2, SET, SFPQ, SFRP5, SFSWAP, SGK1, SHC1, SIM2, SIX3, SLC9A1, SMARCA1, SMARCA2, SMARCA4, SMARCC1, SMARCD3, SMARCE1, SNAI1, SNAPC3, SNAPC4, SNCA, SOD2, SOX3, SOX4, SOX5, SOX9, SOX10, SOX11, SP1, SP2, SP3, SP100, SPIB, SREBF1, SRF, SRP9, SRY, TRIM21, SSRP1, STAT2, STAT3, STAT4, STAT5B, STAT6, SYK, T, TAF4B, TAF7, TAF10, TAL1, TARBP1, TARBP2, TBL1X, TBP, HNF1A, GCFC2, ZNF354A, NR2F1, NR2F2, KLF10, NR2E1, TMPO, TNFRSF1A, TNNI2, TOP2A, TP73, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TRPS1, TSC1, TSG101, TTF1, TULP3, TNFSF4, TYMS, UBB, UBE2D1, UBE2D2, UBE2L3, UBE2V1, UBE3A, SUMO1, UCP1, SCGB1A1, NR1H2, USF1, VAV1, VDR, VEGFA, EIF4H, WFS1, WNT1, WNT11, XRCC5, YY1, YWHAH, ZFP37, ZFPL1, ZFX, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF33B, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF221, ZNF91, ZNF99, ZNF124, ZNF131, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF208, ZNF214, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZP3, ZXDA, PRDM2, LRP8, FZD5, MAFK, ARHGEF5, FOSL1, FGF23, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, SMC1A, USP9Y, ARID1A, HIST1H4I, PICALM, CDC45, EOMES, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NR0B2, UTF1, DYRK2, CUL3, CUL2, TTF2, KLF11, SMARCA5, OGT, IKBKG, IKBKAP, HAT1, GAS7, PIR, BLZF1, KHSRP, PRKRA, STK16, RGS20, RUVBL1, KLF7, TP63, EIF4EBP3, CHRD, DYNLL1, EIF3F, EIF3G, EIF4G3, TRADD, EED, RIPK1, RIPK2, CREG1, SAP30, HESX1, PER3, TAX1BP1, EIF2B3, EIF2B2, BUD31, PHOX2B, FUBP3, HIST1H3F, HIST1H2AG, RPS6KA4, TNFSF18, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, USP2, PDLIM1, SMC3, CBFA2T2, DYRK1B, CTDP1, ARHGEF2, BMP15, CCPG1, RPS6KA5, ITGB1BP1, ZNF235, COPS2, HMGN3, TRIP4, RECQL5, ZRANB2, HAND1, ZNF264, EIF2AK3, FHL5, ONECUT2, LITAF, TBPL1, TMEM59, ZNF254, CIR1, NR1D1, CLOCK, SOX13, RBM39, CREB5, RNF14, PPM1F, ZNF516, SAFB2, EIF5B, PHF14, KDM4A, VGLL4, BZW1, PUM1, ST18, ZNF646, VPRBP, USP34, SETD1A, ZNF536, ZFYVE16, EIF4A3, RB1CC1, ARHGEF11, ZEB2, ZBTB24, ZNF518A, EPM2AIP1, RNF10, ZBTB5, RBM8A, NR1I3, NR1H4, NR1D2, RBX1, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, PQBP1, ZNF263, TRAP1, YAF2, TRIM28, ZNF197, ZNF256, ALYREF, RNF41, EIF1, OLIG2, DENND4A, IRX5, RAMP3 |
1825 | GO:0032989 | 0.01 | 1.41 | 65.36 | 82 | 231 | cellular component morphogenesis | ACTN4, ACTN1, ADAM8, ADD1, ANXA1, ATP2B2, AXL, BMP4, CASP9, CASQ1, CASQ2, CAV3, CD9, COL1A1, CLDN3, CRYGB, DAPK3, COCH, DIAPH1, LPAR1, EP300, ERG, F2, PTK2B, FBLN1, FGA, FGD1, FGR, GAS2, GP1BA, HAS2, HEXB, HGF, FOXA2, HPN, ICAM1, IDUA, RBPJ, IHH, ITGA4, ITGA7, KDR, LIPA, SMAD3, SMAD7, P2RX7, PALM, PRKAR1A, PROX1, PTN, PTPN6, RAB1A, RAC3, RB1, S100A4, S100A13, SALL1, SNAI1, SOX9, SPARC, ST14, STC1, TAL1, TTC3, TYRO3, UPK3A, CLRN1, VDR, WNT11, EOMES, FZD4, FZD7, ADAM15, LATS1, ARHGEF2, ZMYM6, ITGB1BP1, SLC9A3R1, TBPL1, WDR1, FRY, TRIM28 |
1826 | GO:0019220 | 0.01 | 1.41 | 70.88 | 89 | 256 | regulation of phosphate metabolic process | ADAR, APLP2, APP, ARR3, ATF3, BARD1, BDKRB1, CAV3, CCNE1, CDC25A, CDC25C, CDK4, CDKN2D, CHAD, CKS1B, CRY2, CRYBA1, DCN, DLG2, DLG3, DUSP1, EPHA2, ENSA, EPHB1, FBLN1, GNAQ, GP1BA, HHEX, FOXA2, HPN, HRC, HRG, HSPB1, ID1, SMAD6, SMAD7, MEN1, PRDX1, PCP4, PPP2R1A, PPP2R1B, PPP2R2A, PPP2R5D, PRKAB2, DNAJC3, PRPSAP1, PTPN2, PTPN6, PTPRJ, PTPRR, RAC2, RAD51, RANBP2, RB1, RBL2, RRAS, ATXN7, SET, SORL1, SPINK1, STYX, TAF7, TARBP2, NR2F2, HSP90B1, TSC1, TSG101, UVRAG, AKAP1, IKBKAP, DYNLL1, SOCS3, DIRAS3, SOCS6, SLIT2, SLC9A3R1, EIF2AK3, GMFG, PPM1F, SFI1, SMG7, NUAK1, RANBP9, CTDSP2, ATP6AP2, FARP1, RNF41, CTDSPL, SPRY1 |
1827 | GO:0019953 | 0.00 | 1.40 | 111.76 | 139 | 383 | sexual reproduction | ACOX1, ADCYAP1R1, NR0B1, ANG, ANGPT2, BIRC3, ARNTL, ATRX, AXL, BAD, BAX, BBS4, BCL2L1, BIK, PRDM1, BMP4, BRCA2, BRDT, CCNB1, CD9, CDC25C, CXADR, CYLC1, CYLC2, DAZ1, ACE, DIAPH2, DLD, DNM2, DNMT3A, PHC2, CELSR2, ETV5, PTK2B, FANCF, FANCG, FSHB, FSHR, GATA4, GDF9, B4GALT1, GLRA1, GLRB, HIST1H1T, HIST1H1A, HOXD9, HOXD10, HPGD, IGF1, IGF2R, IHH, IL1R1, IL12B, ING2, ITGB1, KIT, KRT9, LIMK2, SMAD1, SMCP, MFGE8, ODF1, CLDN11, OVGP1, OVOL1, SERPINA5, PGR, PPP2R1A, PRKACG, PRKAG1, PRM2, PTGS2, RAD23B, RAD51C, RARA, RNF2, RPS6KA2, RPS6KB1, SBF1, SEPP1, SMARCA2, SMARCA4, SOX3, SOX9, SPAG4, SPAM1, SPINK1, STAT3, STYX, T, TAF4B, TARBP2, TBP, NR2F2, NR2C2, TRPC3, TSPY1, TYRO3, UBE3A, ZAN, EIF4H, YY1, ZNF35, ZNF148, ZP3, DNALI1, FOSL1, AAAS, IFT88, NRIP1, USP9X, USP9Y, TPST2, FKBP6, RUVBL1, TP63, PDE5A, DYNLL1, AKAP4, SGPL1, EIF2S2, HERC2, RNF8, RGN, FAM50A, BMP15, PICK1, ADAMTS2, TBPL1, CLOCK, SPAG6, PUM1, CEP57, UTP14C, SPATA2, KIAA0196, REC8, BCL2L11, AKAP9 |
1828 | GO:0010876 | 0.02 | 1.40 | 54.43 | 68 | 186 | lipid localization | ABCA1, ABCA2, ABCA3, ABCA4, ACACB, AGTR1, AGTR2, ALB, ABCD1, ANXA1, APOF, APOH, TSPO, C3, VPS51, SLC25A20, CD36, SCARB1, AKR1C4, CHKA, CLU, CPT1B, CPT2, CRH, CRP, ACE, DRD3, GALR1, GDF9, GM2A, GOT2, HEXB, ITGAV, KCNN4, LCAT, LIPC, NTSR1, OSBP, P2RX4, P2RX7, P2RY2, SERPINA5, PRKAB2, PSAP, PTCH1, PTPN2, ABCD3, RXRA, SLC10A1, SLCO2A1, SLCO1A2, SORL1, STAT5B, SYK, NR1H2, NRIP1, SLC10A3, FZD4, CYP4F2, DGAT1, ABCC3, SLC9A3R1, LIPG, OSBPL2, NR1H4, ATP9A, COL4A3BP, ABCC4 |
1829 | GO:0046907 | 0.00 | 1.40 | 85.78 | 107 | 305 | intracellular transport | ABCA1, ABCA2, ACACB, ACTN4, AP2B1, ABCD1, APP, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, KIF1A, BBS4, BCL2L1, BICD1, BSG, CACNA1A, CACNB1, CACNG1, SLC25A20, CAMK2A, CD74, AP2M1, AP2S1, CNP, CPT1B, CPT2, SLC25A10, CTTN, EYA2, FTL, GNAS, HK2, IFIT1, ITGB1, KIF5A, KIT, LTBP2, RAB8A, MYO1B, OPA1, PALM, CHMP1A, PFN2, SEPT5, PRKAB2, PRKCI, PTCH1, RAB3A, RAB27A, RANBP1, RPGR, CLIP1, RTN2, S100A13, SNAP25, SPG7, STXBP2, SYN1, TNNC1, UBB, UCP1, UVRAG, VDAC1, WAS, LAT2, ZP3, TUBA1A, AP3B2, PICALM, UXT, SLC25A12, SSNA1, STX11, SNAP23, LIN7A, HERC2, SLC25A14, ARHGEF2, RASSF9, DCLK1, SNAP29, KIF3B, PICK1, AKAP12, CLINT1, PUM1, RIMS2, IFT140, RIMS3, DNAJC6, GOLGA5, HDAC6, PDCD6, TOM1, AP1M2, SCAMP2, ATP9A, COL4A3BP, SLC25A13, SLC25A15, STAM2, RAMP3 |
1830 | GO:0044802 | 0.00 | 1.40 | 153.01 | 189 | 524 | single-organism membrane organization | ABCA1, ABCA4, ANXA1, ARCN1, ARF1, BAD, BAX, BCL2A1, BCL2L1, BNIP3L, BSG, CACNA1A, CACNB1, CAMK2A, CASP8, CAV3, CCNB1, CD9, CD59, CDH1, CDK5, AP2M1, CLU, CLTC, CNP, COPA, COPB1, CSNK1D, DLG2, DLG3, DNM2, DPP6, EPHA2, EMD, EMP2, EYA2, FAU, FLOT2, FYB, GDI1, GNAI3, GOLGA2, GOLGA4, GRIA1, HK2, HSPA4, IFNG, INSIG1, ITGA4, ITGAL, ITGB1, JUP, KCNN4, MAL, RAB8A, NRCAM, NUP98, OPA1, P2RX7, PALM, SERPINA5, PDPK1, PPP2R1A, PPP2R2A, PPP6C, PPT1, PRKCB, PRKCI, PTCH1, PTEN, PEX19, PEX5, RAB1A, RAB3A, RAC1, RANBP2, RAP2A, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, CLIP1, S100A9, TRAPPC2, SLAMF1, SLC9A1, SLC12A1, SNAP25, SNCA, SPAG4, SPAM1, SPTA1, SPTB, SRP9, SRP14, SSR3, STAT3, SYT1, SYT4, CNTN2, TAZ, TNFRSF1A, TSG101, TULP1, TULP2, TULP3, SUMO1, UVRAG, VIL1, VRK1, WRB, YWHAH, YWHAZ, NUP214, AAAS, MADCAM1, DYSF, EEA1, CUL3, TPST2, OGT, BLZF1, USO1, SSNA1, NUMB, DYNLL1, VAMP8, STX11, SNAP23, LIN7A, RPL14, SYT7, SEC22C, CCNB2, VAPB, VAPA, RAB11B, ITGB1BP1, COPB2, SNAP29, RPL23, SLC9A3R1, PEX16, PICK1, GOSR1, TMEM59, BAG4, SEC22B, GOSR2, NUP155, NUP93, RAPGEF2, RUBCN, SPCS2, TOMM20, C2CD5, MFN2, BCL2L11, ATP9A, ARFRP1, STX6, RAMP3, ZMPSTE24 |
1831 | GO:0045184 | 0.00 | 1.39 | 349.43 | 424 | 1194 | establishment of protein localization | ABAT, ABCA1, ABL1, ABL2, ACTN4, ACTL6A, ACVR2B, ADAM8, ADAR, AP2B1, AGTR2, ALOX15B, ANG, ANGPT1, SLC25A4, ANXA1, ANXA4, ANXA5, APBB1, ARCN1, ARF1, ARF4, ARF5, ARL2, ARNTL, RERE, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, BAD, BARD1, BAX, BBS4, BCL2L1, BCL3, BLK, BMP4, BMPR1A, BNIP3L, BRCA2, BSG, BTF3, TSPO, VPS51, CACNA1A, CACNB1, CAMK2G, CANX, CASP5, CASP8, CAV3, CBLB, CD3G, CD14, CD36, SCARB2, CD40, CD58, CD63, CD74, CDH1, CDK5, CDKN1A, CENPF, CHRM1, CHRM3, AP2M1, AP1S1, AP2S1, CLU, CLTC, CNR1, COL1A1, COPA, COPB1, CRH, CRP, CSE1L, CSF1R, CSNK2A2, CTSK, DKC1, DMBT1, DNM2, DRD3, EDA, EFNA5, EGR2, EPHA2, EIF5A, EMD, CTTN, ENSA, EPHA5, EPS15, F2R, FBLN1, FAU, FGA, FGF9, FGR, FLOT2, FYB, GATA3, GCG, KAT2A, GDI1, GDI2, GFER, GHSR, GLE1, GLUD1, GNAQ, GNAS, GOLGA4, GPLD1, GPM6B, GPR26, FFAR1, GUK1, HIST1H1B, HCLS1, NRG1, HK2, HMGCR, FOXA2, HNMT, HSPA4, HSPA9, IFIT1, IFNA2, IFNG, IGF1, RBPJ, IL1A, IL1RN, IL10, IL12B, IL13, TNFRSF9, IL18, INS, ISL1, ITGA2, ITGB1, ITPR1, ITPR3, JUN, JUP, KCNA5, KCNC2, KCNJ11, KCNN4, KCNS3, KPNA1, KPNA2, KPNA3, KPNA4, IPO5, LAMP2, LLGL2, LTBP2, SMAD3, RAB8A, TONSL, NUP98, OAZ1, OAZ2, OXCT1, P2RX7, PAEP, PRDX1, PALM, PAM, PCM1, CHMP1A, PCSK5, PDPK1, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PPID, PPM1B, PPT1, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCB, PRKCE, PRKCI, PRKCQ, MAPK1, MAPK3, PSMB7, PSMD8, PSMD9, PTCH1, PTGS2, PTPN14, PTPRN, PTPRN2, PEX19, PEX5, RAB1A, RAB3A, RAB3B, RAB4A, RAB5A, RAB5B, RAB6A, RAB27A, RABIF, RAC2, RAF1, RAN, RANBP2, RANGAP1, RAP1A, RAP2A, REST, RFX3, RNASE2, RPGR, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, CLIP1, RTN2, RYR2, S100A12, S100A13, CX3CL1, SFRP5, SIX3, SLC2A2, SLC9A1, SLC12A1, SLC15A1, SNAP25, SNX2, SORL1, SOX4, SP100, SREBF1, SRP9, SRP14, SSR3, STAT3, STXBP2, STXBP3, STYX, SYK, SYT5, TACR2, CNTN2, HNF1A, DYNLT1, TNFRSF1A, HSP90B1, TRAF2, TRH, TRIP6, TRPM2, TRPS1, TSG101, TNFSF4, UBE2L3, UFD1L, NR1H2, VIL1, VIP, WRB, YWHAH, YWHAZ, ZIC1, ZBTB17, ZP3, FZD5, SCG2, ARHGEF5, NUP214, AAAS, AP3B2, AKAP1, CLTCL1, BAP1, FZD7, NR0B2, DYRK2, OGT, AP3B1, BLZF1, RGS20, RUVBL1, USO1, SSNA1, AKR1C3, DYNLL1, TNKS, VAMP8, STX11, TNFSF14, SNAP23, IL18R1, LIN7A, IQGAP1, AKAP4, AP1M1, HERC2, AP3D1, SELENBP1, ATP6V0E1, CDKL2, RPL14, SYT7, UNC119, ATP6V0D1, SEC22C, RABEP1, IL1RL1, ARHGEF2, RASSF9, ZW10, RAB11B, ITGB1BP1, COPB2, TRIP11, HMGN3, SNAP29, RPL23, RAB33A, RAB9A, SLC9A3R1, ZFYVE9, NRXN1, COG1, PEX16, EIF2AK3, PICK1, AKAP6, ATG5, CABP1, LITAF, GOSR1, TMEM59, BAG4, APBA3, ATP6V1G1, SEC22B, VPS26A, GOSR2, NR1D1, CLOCK, AKAP12, RAB36, NUP155, IPO13, NUP93, RIMS2, CEP57, IFT140, ACAP1, ZFYVE16, ATG13, SNX17, KIAA0586, SPCS2, TOMM20, C2CD5, SNAP91, KIAA0196, FAM20B, MFN2, NR1H4, HDAC6, PDCD6IP, PDCD6, BCL2L11, TOM1, AP1M2, SAE1, SCAMP2, KIF20A, ARFRP1, TRIM28, NUTF2, STX6, STAM2, RAMP3 |
1832 | GO:0080090 | 0.00 | 1.39 | 454.59 | 543 | 1689 | regulation of primary metabolic process | ABAT, ABCA1, ABCA2, ACACB, ACTN4, ACTL6A, ACTN1, ADCYAP1R1, AEBP1, AES, NR0B1, AHR, ALX3, ANXA1, ANXA3, ANXA4, APBB2, APOH, ARF1, ARF4, PHOX2A, ASCL1, ASCL2, RERE, ATP1A1, ATR, ATRX, BACH1, BBS4, BCL9, PRDM1, BPGM, BRCA2, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTK, CAT, RUNX2, CBL, CD3D, TNFSF8, SCARB1, CDA, CDK11B, CDH1, CDK8, CDX2, CEBPE, CENPB, CHD2, CHD4, CHRNB2, CHUK, CLK1, CLK3, CLTC, CMKLR1, CNR1, COL1A1, CREB1, CRX, CTH, CTNND1, CTNND2, CYP27B1, DBP, DDX5, DFFA, DHCR7, DHFR, DKC1, DLD, DLX5, DNM2, DNMT3A, DRD3, DRD5, ARID3A, ATN1, RCAN1, TSC22D3, DTX1, E2F5, E2F6, E4F1, EBF1, EDA, S1PR1, CELSR2, EGR2, EGR3, EGR4, ELAVL2, ELF1, ELF3, ELK1, ELK3, EMX1, EMX2, EN1, EPHA5, EYA4, ERCC3, ERCC4, ERF, ERG, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EYA2, EZH1, FBN1, EFEMP1, FOXD1, FLII, AFF2, FSHB, NR5A2, FZD2, GALR1, GATA4, GATA6, GCGR, GDNF, GLO1, GNAI3, GNAS, GSC2, GTF2I, GTF3A, BRF1, GUCA1A, GUCA2A, GUCA2B, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H2AD, H3F3B, HAS2, HAS3, HBE1, HDGF, HEXB, HIC1, HIVEP2, HLF, HMGN1, HMGA1, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HNRNPC, HOXC10, HOXC11, HOXD4, HOXD8, HOXD9, HOXD10, HOXD12, HPRT1, HRH1, HSBP1, HSF4, ID2, IDH1, SP110, RBPJ, IHH, ING2, INSIG1, ITGA6, IRF5, JUNB, JUND, JUP, KCNK2, KPNA1, KPNA2, LMO1, SMAD9, MAZ, MEOX2, CIITA, AFF1, FOXO4, TONSL, NRF1, YBX1, NTSR1, NVL, OAS1, OAS3, ORC1, ORC2, OTX1, OTX2, OVOL1, P2RY11, PALM, PAM, PAX3, PAX9, PCK1, PCNA, CHMP1A, PDE8A, PDK4, PEG3, PGAM1, PGR, PHF2, PPID, PPP1R8, PPP4C, PRKCB, PRKCI, PTCH1, PTGIS, PTH, PTGS2, PTPN14, PURB, RAD21, RANBP2, RARB, RBBP4, RBBP6, RBBP8, RBL2, RCVRN, DPF2, RFC1, RFX1, RFX3, RFXAP, RLF, RNF2, RNF6, RPA2, RPL6, RPS26, RRM2, RXRG, RYR2, S100A1, S100A11, SALL1, SATB1, ATXN7, TRAPPC2, SETMAR, SFPQ, SFRP5, SRSF7, SFSWAP, TRA2B, SGK1, SIM2, SIX3, SLC9A1, SMARCA1, SMARCA2, SMARCA4, SMARCD3, SMARCE1, SNAI1, SNAPC3, SNAPC4, SOD2, SOX3, SOX5, SOX10, SOX11, SP1, SP2, SP3, SP100, SPIB, SRF, SRPK2, SRY, SSRP1, STAT2, STAT3, STAT4, STAT6, SUPV3L1, T, TACR3, TAF4B, TAF10, TAL1, TARBP1, TBL1X, TBP, HNF1A, GCFC2, ZNF354A, NR2F1, KLF10, NR2E1, TMPO, TNNI2, TOP2A, NR2C1, NR2C2, TRAF1, TRIP6, TTF1, TULP3, TNFSF4, TYMS, UBE2D2, UBE2V1, UCP1, SCGB1A1, UNG, USF1, VAV1, VDR, VIPR2, XRCC5, YY1, YWHAH, ZFP37, ZFPL1, ZFX, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF33B, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF221, ZNF91, ZNF99, ZNF124, ZNF131, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, TRIM25, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF177, ZNF180, ZNF189, ZNF208, ZNF214, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZXDA, PRDM2, MAFK, PDHX, FOSL1, ANP32A, ZNF239, DPF1, NRIP1, CHAF1B, USP9X, KDM5C, SMC1A, USP9Y, ARID1A, HIST1H4I, CDC45, EOMES, FZD6, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NR0B2, UTF1, NSMAF, DYRK2, CUL2, TTF2, KLF11, SMARCA5, PIK3R3, HAT1, GAS7, PIR, FCN3, BLZF1, KHSRP, STK16, RGS20, RUVBL1, KLF7, AKR1C3, CHRD, DYNLL1, TNKS, SRSF9, TNFSF13, CREG1, SAP30, HESX1, PER3, TAX1BP1, BUD31, PHOX2B, FUBP3, HIST1H3F, HIST1H2AG, TAF1B, TAF1A, RNF8, BAZ1B, UBA3, USP2, PDLIM1, SMC3, CBFA2T2, DYRK1B, CTDP1, AURKB, CCPG1, ZNF235, COPS2, TRIP11, HMGN3, TRIP4, RECQL5, ZRANB2, HAND1, ZNF264, FHL5, IL27RA, ONECUT2, LITAF, TBPL1, ZNF254, CIR1, GTPBP1, GABBR2, NR1D1, CLOCK, BRE, SOX13, RBM39, CREB5, AKAP12, GUCA1C, ZNF516, SAFB2, PHF14, VGLL4, BZW1, DHX34, ST18, RUBCN, ZNF646, VPRBP, USP34, SETD1A, ZNF536, ZFYVE16, ARHGEF11, ZBTB24, ZNF518A, EPM2AIP1, RNF10, ZBTB5, NR1I3, NR1D2, DMTF1, NR2E3, ZBTB33, PARP3, PQBP1, ZNF263, YAF2, TRIM28, ZNF197, ZNF256, ALYREF, OLIG2, DENND4A, IRX5, RAMP3 |
1833 | GO:0071702 | 0.00 | 1.39 | 375.73 | 454 | 1297 | organic substance transport | ABCA3, ABCB7, ABCA4, ABL1, ABL2, ACTN4, ACTL6A, ACVR2B, ADAM8, ADAR, AP2B1, ALOX15B, ANG, ANGPT1, SLC25A4, ANXA4, ANXA5, APOF, APBB1, APOH, ARCN1, ARF1, ARF4, ARF5, ARL2, ARNTL, RERE, ATP6V1B2, ATP6V1E1, ATP6V0B, ATP6V0A1, ATP6AP1, BAD, BARD1, BBS4, BCL3, BLK, BMP4, BMPR1A, BNIP3L, BSG, BTF3, C3, VPS51, CA1, CA4, CA6, CACNB1, CAMK2G, CANX, CASP5, CBLB, CD3G, CD14, SCARB2, CD40, CD58, CD63, CD74, CDH1, CDK5, CDKN1A, CENPF, CHKA, CHRM1, CHRM3, AP2M1, AP1S1, AP2S1, CLTC, COL1A1, COPA, COPB1, CRHBP, CRP, CSE1L, CSF1R, CSNK2A2, CTSK, DMBT1, DNM2, EDA, EFNA5, EGR2, EIF4E, EIF5A, EMD, CTTN, ENSA, SLC29A1, EPHA5, EPS15, F2R, FBLN1, FAU, FGA, FGF9, FGR, FYB, G6PC, GATA3, GCG, KAT2A, GDF9, GDI1, GDI2, GFER, GHRHR, GHSR, GIF, GJB1, GPC3, GLE1, GLUD1, GM2A, GNAQ, GNAS, GOLGA4, GPLD1, GPR26, FFAR1, GUK1, HBA1, HBA2, HCLS1, NRG1, HHEX, HK2, HMGCR, FOXA2, HNMT, HPX, HRG, HSPA4, HSPA9, HTR2C, IFIT1, IFNA2, IFNG, IGF1, RBPJ, IL1A, IL1RN, IL10, IL12B, IL13, TNFRSF9, IL18, INS, ISL1, ITGAV, ITGB1, ITPR1, ITPR3, JUN, JUP, KCNA5, KCNC2, KCNJ11, KCNN4, KCNS3, KISS1, KPNA1, KPNA2, KPNA3, KPNA4, IPO5, LAMP2, LLGL2, LTBP2, SMAD3, RAB8A, TONSL, NUP98, OAZ1, OAZ2, OXCT1, PAEP, PRDX1, PALM, PAM, SERPINA5, PCM1, CHMP1A, PCSK5, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PPID, PPM1B, PPT1, PRKAA1, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCB, PRKCE, PRKCI, PRKCQ, MAPK1, MAPK3, PSAP, PSMB7, PSMD8, PSMD9, PTH, PTGS2, PTPN14, PTPRN, PTPRN2, PEX19, PEX5, RAB1A, RAB4A, RAB5A, RAB5B, RAB6A, RAB27A, RABIF, RAC2, RAF1, RAN, RANBP2, RANGAP1, RAP1A, UPF1, REST, RFX3, RHAG, RHCE, RHD, RNASE2, RPGR, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS6KB1, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, CLIP1, RTN2, SORT1, S100A8, S100A9, S100A12, S100A13, CX3CL1, SFRP5, SRSF1, SRSF5, SRSF7, SIX3, SLC2A2, SLC2A3, SLC2A4, SLC2A5, SLC4A1, SLC5A2, SLC9A1, SLC15A1, SNX2, SORL1, SOX4, SP100, SREBF1, SRP9, SRP14, SSR3, STAT3, STXBP2, STXBP3, STYX, SYT5, TAF7, SERPINA7, HNF1A, DYNLT1, HSP90B1, TRAF2, TRIP6, TRPM2, TRPS1, TSC1, TSG101, TNFSF4, UBE2L3, UFD1L, UPK3A, VIL1, VIP, YWHAH, YWHAZ, ZIC1, ZBTB17, ZP3, FZD5, SCG2, ARHGEF5, NUP214, AAAS, AP3B2, AKAP1, SLC14A2, CLTCL1, BAP1, FZD4, FZD7, LTBP4, NR0B2, DYRK2, OGT, PIK3R3, AP3B1, BLZF1, KHSRP, RGS20, RUVBL1, USO1, SSNA1, AKR1C3, DYNLL1, TNKS, STX11, PEA15, SRSF9, RIPK1, TNFSF14, IL18R1, LIN7A, IQGAP1, ARHGEF7, AP1M1, HERC2, AP3D1, SELENBP1, ATP6V0E1, CDKL2, RPL14, SYT7, UNC119, ATP6V0D1, SEC22C, RABEP1, IL1RL1, ARHGEF2, RASSF9, ZW10, RAB11B, ITGB1BP1, COPB2, TRIP11, HMGN3, SNAP29, RPL23, RAB33A, RAB9A, ZFYVE9, SLC22A8, NRXN1, COG1, SLC22A14, PEX16, EIF2AK3, AKAP6, ATG5, CABP1, SLC4A7, LITAF, GOSR1, BAG4, APBA3, ATP6V1G1, SEC22B, VPS26A, GOSR2, NR1D1, CLOCK, AKAP12, RAB36, NUP155, IPO13, NUP93, RIMS2, CEP57, IFT140, ACAP1, ZFYVE16, EIF4A3, ATG13, SNX17, DHX38, SPCS2, CKAP5, TOMM20, C2CD5, ZC3H11A, OSBPL2, SMG7, SNAP91, KIAA0196, FAM20B, MFN2, RBM8A, HDAC6, PDCD6IP, PDCD6, TOM1, AP1M2, SAE1, ABCC5, ABCB6, SCAMP2, ATP9A, COL4A3BP, KIF20A, ARFRP1, TRIM28, ALYREF, NUTF2, STX6, SLC35B1, STAM2, RAMP3 |
1834 | GO:0051258 | 0.04 | 1.39 | 41.85 | 52 | 143 | protein polymerization | ABL1, ADD1, ANG, ARF1, ARHGAP6, ARL2, BBS4, CAPG, CASQ1, CASQ2, CAV3, CSNK1D, DIAPH1, DIAPH2, CTTN, PTK2B, FGA, GOLGA2, GRB2, HCLS1, UBE2K, ICAM1, PFN2, PRKCE, RAC1, RPS3, CLIP1, CCL21, SGK1, SNCA, SPTA1, SPTB, TBCD, TUBG1, VDAC2, VIL1, WAS, ZNF207, GAS7, LATS1, SLIT2, PICK1, BAG4, GMFG, RANBP9, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, AKAP9, ABI2 |
1835 | GO:0044765 | 0.00 | 1.39 | 215.24 | 264 | 803 | single-organism transport | ABCA3, ABCB7, ACTB, ACTL6A, ADCY1, ADCY7, ADD1, ADD3, AMPH, ANXA11, APOF, APOH, ARCN1, ARF4, ARL1, KIF1A, BARD1, BBS4, BCL2A1, BCL2L1, BGLAP, BICD1, BNIP3L, BSG, C3, VPS51, CASP8, CD3G, SCARB2, CD59, CDX2, CEBPE, CHKA, AP1S1, CNP, COPB1, CSF2, CSNK1D, CSNK2A2, CTSK, CD55, DYNC1H1, EGR2, EIF4E, EIF5A, EMP2, EPS15, EYA2, F7, F10, FAU, FCGR2A, FCGRT, FCN2, G6PC, GAS1, KAT2A, GDI1, GFER, GJA3, GJB1, GJB2, GPC3, GLE1, GM2A, GOLGA2, GOLGA4, GOLGB1, GPR26, GUK1, HAS2, HBD, HBE1, HHEX, HNMT, HPX, HSPA9, INSIG1, ITGA2, EIF6, KIF5A, LIMK1, MAL, MAP1B, MFGE8, MYO1B, OAZ1, OAZ2, OPA1, OPHN1, PALM, SERPINA5, PCM1, CHMP1A, ABCB1, PPP6C, PRKAA1, PROC, PSMB7, PSMD8, PTEN, PTH, PTK2, PTPN14, ABCD4, RAB5B, RAB6A, RAC1, RANGAP1, RAP1GAP, RARA, UPF1, RNASE2, RPGR, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS6KB1, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, CLIP1, RTN2, SORT1, TRAPPC2, SRSF1, SRSF5, SRSF7, SFTPD, ITSN1, SLAMF1, SLC2A3, SLC2A4, SLC2A5, SNX2, SORL1, SP100, SPG7, SPTA1, SPTB, SRP9, SRP14, SSR3, STYX, SERPINA7, ICAM5, HSP90B1, TULP1, UBE2L3, UBE3A, UFD1L, UVRAG, VAV1, VIL1, WAS, WRN, YWHAZ, ZBTB17, TUBA1A, FZD5, SLC25A16, AAAS, AP3B2, CLTCL1, BAP1, UXT, EEA1, CUL3, OGT, PIK3R3, AP3B1, FCN3, BLZF1, RUVBL1, USO1, SSNA1, DYNLL1, PEA15, SRSF9, PROZ, EIF2S2, AP1M1, AP3D1, CDKL2, RPL14, UNC119, SEC22C, RASSF9, ZW10, DCLK1, VAPB, VAPA, ITGB1BP1, COPB2, TRIP11, KIF3B, COG1, GOSR1, BAG4, SEC22B, VPS26A, GOSR2, AKAP12, CLINT1, PUM1, RUBCN, USP6NL, IFT140, ZFYVE16, ATG13, SNX17, DHX38, RGP1, DNAJC6, C2CD5, ZC3H11A, OSBPL2, SMG7, SGSM2, FAM20B, MFN2, RBM8A, GOLGA5, HDAC6, BCL2L11, HMGXB4, TOM1, AP1M2, SAE1, ABCB6, SCAMP2, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, ARFRP1, WASF2, ALYREF, STX6, STAM2 |
1836 | GO:0022607 | 0.00 | 1.38 | 357.72 | 432 | 1240 | cellular component assembly | ABCA1, ABL1, ABL2, ACACB, ACADS, ACAT1, ADAR, ADD1, AP2B1, AHR, ALAD, BIN1, ANGPT1, ANXA5, ANXA6, APAF1, BIRC3, BIRC5, APP, AQP1, ARF1, ARG1, ASL, ATP6V0A1, ATR, ATRX, BAD, ADGRB2, BAX, BBS4, BICD1, BIK, BLK, KLF5, CACNA1A, CAMK2G, CAPG, CASP8, CASQ1, CASQ2, CAT, CAV3, CCNB1, CD3E, CD3G, CD36, ENTPD2, CD40, CD59, CD74, CDA, CDK2, CDK5, CENPA, CENPE, CENPF, CHD4, CHRNB2, CHRNB4, CIRBP, AP2S1, CLU, CLNS1A, COL1A1, COL6A1, COL6A2, COX15, CREB1, CRYAB, CSF2, CSNK1D, CTGF, CTH, CYBA, DARS, DDX1, DDX3X, DDX6, DHPS, DIAPH1, DIAPH2, DNM1, DYNC1H1, DNM2, DPYSL3, S1PR1, LPAR1, CELSR2, EPHA2, EMP2, EPHB1, EPHB2, EPHB3, EPRS, EPS15, FGA, FGD1, FLOT2, CENPI, GFAP, GHSR, GLRA1, GLRB, GOLGA2, GPC1, GPM6A, GRB2, GRB7, GRIA1, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H1T, HIST1H2BB, H3F3B, HIST1H1A, HAS1, HAS2, HAS3, HBA1, HBA2, HBE1, HCLS1, NRG1, HIP1, UBE2K, HMGCR, HMGA1, ONECUT1, HPRT1, HSF4, DNAJB2, HSPA4, ICAM1, ID1, IGF1R, IHH, IL1RAP, IL2RB, TNFRSF9, IMPDH2, INS, INPPL1, INSIG1, EIF3E, IRAK1, EIF6, ITGB5, ITPR3, JUN, KCNA1, KCNA3, KCNA4, KCNA5, KCNC2, KCND2, KCND3, KCNJ2, KCNS1, KCNS2, KCNS3, KIT, KPNA3, IPO5, LCAT, LIMK1, LIPC, SMAD1, SMAD6, RAB8A, MYO1B, NUBP1, CNOT2, NRCAM, NTRK2, NTRK3, NUP98, OAS1, OAT, OCRL, OPHN1, OTX2, OXTR, P2RX1, P2RX3, P2RX4, P2RX7, PALM, PAM, PCM1, CHMP1A, PFN2, PIK3C2A, PIP4K2A, PLN, PPID, PPP2R1A, PPP2R1B, PPP5C, PPP6C, PRKAA1, PRKAR1A, PRKCE, PRKCQ, MAPK3, PROX1, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD4, PSMD8, PSMD9, PSMD11, PEX5, RAB1A, RAB5A, RAC2, RAC3, RAD51, RAD51C, RAD51B, RAD51D, RAF1, RALA, RAP1GAP, RAP2A, RB1, RBBP4, RFX3, RFX4, RPGR, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL23A, RPL24, RPL38, RPS3, RPS19, RPS27, RPS27A, RRM1, RRM2, CLIP1, RXRA, RXRG, RYK, SCO1, CCL21, SDC1, TRAPPC2, SELP, SET, SRSF1, SRSF5, SFSWAP, SGK1, SH3BGR, SHMT1, SHMT2, SLC6A4, SLC34A1, SLC22A1, SNAP25, SNCA, SNRPC, SNRPD1, SNRPE, SNRPF, SNX2, SOD2, SORL1, SOX9, SPTA1, SPTB, SRPK2, TRIM21, STXBP3, SYT1, TAF7, TAF10, TAL1, TARBP2, TAZ, HNF1A, GCFC2, TNFRSF1A, TP73, TPBG, HSP90B1, TRAF1, TRAF2, TSG101, TSPY1, TUBG1, UBB, SUMO1, USP4, NR1H2, CLRN1, UVRAG, VBP1, VDAC2, VIL1, WAS, WNT1, XRCC2, YWHAZ, ZNF148, ZNF207, ARHGEF5, FOSL1, IFT88, SF3A2, CLPP, CHAF1B, HIST1H4I, PICALM, CDC45, HIST1H2BL, HIST1H2BN, HIST1H2BM, HIST1H2BF, HIST1H2BH, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, CUL3, SMARCA5, OGT, IKBKAP, HAT1, GAS7, PRPF18, RUVBL1, USO1, TP63, TNKS, EIF3F, EIF3G, SRSF9, DGAT1, TRADD, RIPK1, HRK, SNAP23, PEX11B, LIN7A, AKAP4, SYNJ1, BSN, HIST1H3F, TAF1B, LATS1, ATP6V0D1, PRPF3, SCAF11, ZW10, REPS2, AURKB, SNAP29, SLIT2, RAB33A, SLC9A3R1, NRXN3, KIF3B, ZFYVE9, NRXN1, NRXN2, GRHPR, DDX23, EIF2AK3, PICK1, ATG5, ONECUT2, TBPL1, BAG5, BAG4, GMFG, SEC22B, GOSR2, SNCAIP, FEZ2, PDE4DIP, CEP135, NUP93, CEP57, USP6NL, KNTC1, IFT140, ATG13, PIEZO1, KIAA0586, TOMM20, SPOCK2, RB1CC1, SNAP91, KIAA0196, WDR1, REC8, HDAC6, PDCD6IP, BCL2L11, RANBP9, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, AKAP9, ABI2, TRIM28, FARP1, WASF2, STAM2, ABCC4 |
1837 | GO:0044699 | 0.03 | 1.38 | 47.27 | 59 | 294 | single-organism process | ALDH1B1, ALDH3B2, APOF, C7, VPS51, SCARB2, AP1S1, DIO1, FMO3, GALE, GALK2, GFER, GLE1, GPX2, HIST1H1A, CFHR1, HSPB2, EIF6, IPO5, LIMK2, OSBP, PCK2, PRSS8, PTPN12, RNASE2, SBF1, SERPINB4, SRSF7, SQLE, SERPINA7, ICAM5, TPMT, EIF4H, ZNF35, COIL, RDH16, SRSF9, CES2, CLDN10, FAM50A, CABP1, VPS26A, HS2ST1, IPO13, CLINT1, USP6NL, DHX38, RGP1, ZC3H11A, OSBPL2, SMG7, SGSM2, FAM20B, RBM8A, GOLGA5, HS3ST1, TOM1, SCAMP2, GPA33 |
1838 | GO:0051345 | 0.00 | 1.37 | 113.35 | 139 | 391 | positive regulation of hydrolase activity | ABL2, ADCY1, ADCY7, ADCYAP1R1, ADRBK1, AGTR1, AMPH, ANG, APOH, ARF4, ARHGAP4, ARHGAP5, ARHGAP6, ARHGDIB, ARHGDIG, ARL1, AVPR1B, BCR, CD40, RCBTB2, CHN1, CHN2, CREB1, DNM2, S1PR1, LPAR1, EDNRA, EIF2B1, EPHA2, PTK2B, FGD1, FGFR3, FLT1, FNTA, GCGR, GDI1, GDI2, GM2A, GNA15, GNAQ, GNAS, GNAT1, FFAR1, RAPGEF1, ICAM1, ITGA6, ITGB1, ITPR1, ITPR3, JUN, KIT, LLGL2, NTRK3, OCRL, OPHN1, PCNA, PDPK1, PFN2, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, PRKCE, PRKD1, PTAFR, RAB3A, RAB4A, RABIF, RANBP1, RANGAP1, RAP1A, RAP1GAP, RASA2, RGS1, RGS10, RGS12, RGS13, RPGR, RSU1, RYR2, SBF1, CCL21, CCL22, CCL25, XCL1, CX3CL1, SELE, SETMAR, ITSN1, SIPA1, SOS2, XCL2, TBCD, TRIO, TSC1, SUMO1, NR1H2, VAV1, VEGFA, WNT11, WRN, ARHGEF5, BCAR3, MADD, RGS20, S1PR4, RGS9, IQGAP1, ARHGEF7, EIF2B3, EIF2B2, HERC2, RABEP1, ARHGEF1, ARHGEF2, VAPB, CYTH2, GPR55, TRIP10, ARHGAP29, RIN1, RALGPS1, RAPGEF2, USP6NL, ARHGAP32, ACAP1, ARHGEF11, RGP1, SGSM2, DENND4B, ARHGAP25, SH2D3C, SH2D3A, RASA4, FARP1, RASGRP2, DENND4A |
1839 | GO:0016569 | 0.01 | 1.37 | 69.95 | 86 | 239 | covalent chromatin modification | ACTL6A, APBB1, BRCA2, CCNB1, CDK2, CHEK1, DDB1, DNMT1, DNMT3A, DNMT3B, EP300, EYA2, EZH1, GATA3, GCG, KAT2A, HIST1H1B, HLCS, PRMT1, HSF4, ISL1, JARID2, MEN1, PHB, PHF2, PPP5C, PRKAA1, PRKCB, PRKD1, MAPK3, RAG1, REST, RNF2, SALL1, SATB1, ATXN7, SET, SETMAR, SFPQ, SKP1, SNCA, SREBF1, TAF7, TAF10, TBL1X, TRPS1, KDM6A, UTY, VEGFA, VRK1, PRDM2, KDM5C, KDM5D, HIST1H4I, BAP1, GFI1B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, OGT, HAT1, RUVBL1, EED, RPS6KA4, RNF8, BAZ1B, AURKB, RPS6KA5, TRIP12, GTF3C4, ATG5, CLOCK, PPM1F, KDM4A, VPRBP, USP34, SETD1A, RNF40, USP3, NR1H4, HDAC6 |
1840 | GO:0006631 | 0.03 | 1.37 | 55.31 | 68 | 189 | fatty acid metabolic process | ACACB, ACADM, ACADS, ACOX1, ABCD1, ALOX15B, ANXA1, C3, DAGLA, CBR1, CD74, CNR1, CPT1B, CPT2, CRAT, CYP1A2, CYP2A6, CYP2A13, CYP2F1, DLD, DPEP1, ECH1, EHHADH, ETFA, ETFDH, FAAH, FCER1A, GGT7, GHSR, GPX1, HADHA, HPGD, HSD17B4, INS, INSIG1, IVD, LIPA, LIPC, LIPE, LTA4H, PAM, PDK4, PEX7, PEX13, PRKAA1, PRKAB2, PRKAG1, PRKAR2B, MAPK3, PTGIS, PTGS1, PTGS2, ABCD3, ACSM3, SNCA, SREBF1, STAT5B, ELOVL4, SYK, TNFRSF1A, NR1H2, PDHX, ACOX3, CYP4F2, AKR1C3, SGPL1, RGN, EIF2AK3 |
1841 | GO:0000209 | 0.05 | 1.35 | 45.07 | 55 | 154 | protein polyubiquitination | XIAP, BARD1, CDC27, UBE2K, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, RNF6, RPS27A, SKP2, TRIM21, TRAF2, TTC3, UBB, UBE2D1, UBE2D2, UBE2E2, UBE2H, UBE2L3, UBE2V1, UBE3A, CUL3, TNKS, CDC23, CDC16, RNF8, TRIP12, UBE4A, PSMF1, RNF14, UBE3C, RNF40, HDAC6, RNF41, PSME3, PSMD14 |
1842 | GO:0051171 | 0.00 | 1.35 | 379.42 | 450 | 1359 | regulation of nitrogen compound metabolic process | ABAT, ABCA1, ABCA2, ABL1, ACTN4, ACTL6A, ACTN1, ACVR1B, ADAM8, ADCY7, ADCYAP1R1, ALK, ALX3, ANXA3, APAF1, APBB1, APBB2, XIAP, ARF4, PHOX2A, ARNT, AVPR2, BAX, BCL9, BHMT, BMP1, BMP3, BMP8B, BMPR1A, BRDT, ZFP36L2, KLF9, BTF3, BTK, CALM3, CAMK2A, CBL, CCNB1, CCNC, CCNE1, CCNT2, CD3D, CD86, TNFSF8, SCARB1, CD40, CDK11B, CDH1, CDK2, CDK8, CDKN1A, CEBPE, CENPB, CHD2, CHEK1, CHRNB2, CHUK, CLK1, CLK3, COL1A1, CRH, CRX, CSF2, CSNK2A1, CSNK2A2, CTH, CTNND1, CTNND2, DBP, DCN, DHFR, DKC1, DLX5, DRD5, ARID3A, RCAN1, DTX1, E2F5, EBF1, ECM1, EDA, S1PR1, CELSR2, EGR2, EGR3, EGR4, ELAVL2, ELF1, ELK1, EMX1, EMX2, EPHA5, EYA4, ERCC3, ERCC6, ERG, ESRRG, ETS1, ETV1, ETV2, ETV4, ETV5, EVX1, EWSR1, EYA2, EZH1, F2R, FBN1, EFEMP1, FGF4, FGF7, FGF8, FLII, AFF2, FSHB, FSHR, NR5A2, FZD2, GATA4, GCG, KAT2A, GDF9, GDNF, GHRHR, GPC3, GLO1, GNAS, GSC2, GTF2I, GTF3A, BRF1, GUCA1A, GUCA2A, GUCA2B, HAS2, HAS3, HEXB, HGF, HIP1, HIVEP2, HLF, HMGN1, NR4A1, HMX2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD4, HOXD10, HOXD12, HPN, HPRT1, PRMT1, SP110, IGF2, IHH, IL1A, IL3, ILK, ING2, INSIG1, ITGA6, IRF5, JUP, KIT, KPNA1, KPNA2, LTF, SMAD6, SMAD9, MAZ, MEOX2, KITLG, MGMT, ATXN3, AFF1, FOXO4, PPP1R12A, NRF1, NTRK2, NTRK3, DDR2, NVL, OAS1, OAS3, OAZ1, OAZ2, ODC1, ORC1, OTX1, OTX2, P2RX7, P2RY11, SERPINE1, PAM, PCK1, PCNA, PDE8A, PDPK1, PGR, PPP1R8, PPP2R1A, PPP4C, PRKAG1, PRKAR1A, PRKCB, PRKCI, PRKD1, PRKCQ, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC4, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTPN14, RAC1, RAD21, RAD51, RAF1, RBBP4, RBBP6, RBL2, RCVRN, DPF2, RET, RFC1, RFX1, RFX4, RFXAP, RLF, RNF6, RPA2, RPL6, RRM2, RXRG, RYR2, S100A8, S100A12, ATXN7, TRAPPC2, SETMAR, TRA2B, SGK1, SHC1, SLC9A1, SMARCA1, SMARCC1, SMARCD3, SNAPC3, SNAPC4, SNRNP70, SOD2, SP1, SP2, SPIB, SRPK2, SSRP1, STAT2, STAT4, STAT5B, SUPV3L1, SYK, TACR3, TAF4B, TAF10, TARBP1, HNF1A, ZNF354A, TMPO, TNNI2, TOP2A, NR2C2, TRAF1, TRAF2, TRIP6, TULP3, TYMS, UBE2D2, UBE2L3, UBE2V1, UBE3A, UCP1, UNG, USF1, VAV1, VIP, VIPR2, WNT1, YWHAH, ZFP37, ZFPL1, ZFX, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF26, ZNF28, ZNF32, ZNF33B, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF221, ZNF99, ZNF124, ZNF131, ZNF140, ZNF141, ZNF142, ZNF143, TRIM25, ZBTB17, ZNF155, VEZF1, ZNF165, ZNF180, ZNF207, ZNF208, ZNF214, ZNF223, ZNF225, ZNF229, ZNF232, ZXDA, PRDM2, FZD5, MAFK, ARHGEF5, FOSL1, FGF23, ANP32A, ZNF239, DPF1, CHAF1B, USP9Y, FZD4, FZD7, UTF1, CUL4A, CUL2, TTF2, SMARCA5, OGT, IKBKG, IKBKAP, GAS7, PIR, BLZF1, KHSRP, STK16, RGS20, RUVBL1, KLF7, CHRD, PDE5A, DYNLL1, TRADD, RIPK1, TNFSF13, RIPK2, BUD31, PHOX2B, FUBP3, RPS6KA4, TNFSF18, BAZ1B, PDLIM1, DYRK1B, CTDP1, ARHGEF2, BMP15, VAPB, CCPG1, ITGB1BP1, ZNF235, TRIP11, HMGN3, TRIP4, ZRANB2, ZNF264, FHL5, IL27RA, ONECUT2, PSMF1, LITAF, TBPL1, GTPBP1, BRE, SOX13, RBM39, CREB5, AKAP12, RNF14, GUCA1C, ZNF516, SAFB2, VGLL4, BZW1, ZNF646, USP34, SETD1A, ZFYVE16, RB1CC1, ARHGEF11, ZBTB24, ZNF518A, RNF10, ZBTB5, RBX1, DMTF1, PARP3, PQBP1, ZNF197, ALYREF, RNF41, PSME3, PSMD14, DENND4A, IRX5 |
1843 | GO:0051056 | 0.05 | 1.34 | 48.58 | 59 | 166 | regulation of small GTPase mediated signal transduction | ABCA1, ABL2, ARHGAP4, ARHGAP5, ARHGAP6, ARHGDIB, ARHGDIG, BCR, CHN1, CHN2, DNM2, LPAR1, F2R, FGD1, GDI1, GDI2, RAPGEF1, NRG1, IGF1, ITGB1, KITLG, OCRL, OPHN1, PPP2CB, RAC1, RAC2, RAC3, RAF1, RAP1GAP, RASA2, ITSN1, SIPA1, SOS2, TRIO, VAV1, ARHGEF5, SHOC2, CUL3, OGT, MADD, ARHGEF7, ARHGEF1, DGKI, ARHGEF2, CYTH2, GPR55, TRIP10, SLIT2, ARHGAP29, RALGPS1, ARHGAP32, ARHGEF11, RHOBTB1, DENND4B, MFN2, ARHGAP25, RASA4, FARP1, SPRY1 |
1844 | GO:0016043 | 0.04 | 1.34 | 50.67 | 62 | 199 | cellular component organization | ABCA4, APLP2, ARHGAP5, BCL3, AP1S1, CLCN6, COMP, VCAN, CD55, DLG2, DPP6, ELF3, FBLN2, FTL, FYB, B4GALT1, ICAM2, ICAM4, ITGAD, ITGAE, ITGAL, ITGAM, KCNN4, LAMA4, LTBP2, MAL, MATN3, MFAP3, SERPINA5, SERPINB5, PPIB, PTCH1, PTPRS, RAB3B, RABIF, SGCD, SLC2A4, SLC12A1, SNCB, SNTA1, SPAM1, SRP9, SRP14, SSR3, TULP2, TULP3, UPK2, VAV1, MADCAM1, TPST2, SYT7, CLDN6, RABEP1, RAB11B, SDC3, CLINT1, PUM1, ADAMTSL2, SPCS2, AP1M2, ATP9A, ARFRP1 |
1845 | GO:0016236 | 0.03 | 1.33 | 62.04 | 75 | 212 | macroautophagy | ACTL6A, ANXA5, ATP6V0A1, BNIP3L, TSPO, CAPS, COX8A, CSNK2A2, CTSK, DCN, CTTN, FANCF, FGF7, GABRA5, KAT2A, HK2, KCNK3, KCNQ1, KDR, NTHL1, P2RX5, PDK4, PEX13, PGK2, PIP4K2A, PRKAA1, PRKAB2, PRKAG1, PRKG1, RAB1A, RHEB, RPL28, RPS27A, SCN1A, SLCO1A2, SLC22A3, SNRPD1, SNRPF, SREBF1, STAT2, NR2C2, TSC1, TSG101, UBB, UVRAG, VDAC1, ZBTB17, ZNF189, FZD5, IFT88, CHAF1B, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, RUVBL1, DYNLL1, VAMP8, HIST1H3F, STBD1, SNAP29, RAB33A, CHST3, ATG5, FEZ2, NUP93, RUBCN, ATG13, RIMS3, PHYHIP, TOMM20, RB1CC1, MFN2, FGFBP1, HDAC6 |
1846 | GO:0015849 | 0.05 | 1.32 | 52.39 | 63 | 179 | organic acid transport | ABAT, ACACB, AGTR2, ALB, ABCD1, ANXA1, ARG1, ATP1A2, CACNA1A, CACNB4, SLC25A20, CD36, AKR1C4, CPT1B, CPT2, SLC25A10, CTNS, ACE, DRD3, GOT2, KCNJ10, NTRK2, NTSR1, P2RX4, P2RX7, P2RY2, PRKAB2, ABCD3, RAB3A, RXRA, SLC1A6, SLC6A6, SLC6A7, SLC6A8, SLC6A13, SLC7A1, SLC7A4, SLC10A1, SLCO2A1, SLCO1A2, SLC22A5, SNAP25, SNCA, SYK, SYT1, TRH, TRPC4, TRPV1, SLC7A5, SLC10A3, CYP4F2, SLC25A12, ABCC3, SLC5A6, SLC13A2, SLC16A6, SLC16A5, SLC6A5, SLC9A3R1, NR1H4, SLC25A13, SLC25A15, ABCC4 |
1847 | GO:0065007 | 0.00 | 1.32 | 792.84 | 869 | 3287 | biological regulation | ACPP, ACTG2, ACTL6A, ADAM10, AP2B1, AEBP1, AHR, AK1, ALOX15B, ALX3, BIN1, APBB1, APBB2, KLK3, ARF5, ARG1, RND3, PHOX2A, ARR3, STS, ASCL1, ASCL2, ASIP, ASNS, ASS1, ATF3, ATF4, RERE, BACH1, BCHE, BCL2A1, BCL9, OPN1SW, BHMT, BIK, PRDM1, BMP1, BMP3, BMP8B, BMPR1A, BMX, DST, BPGM, BPI, BRCA2, BRDT, KLF9, KLF5, BTF3, CAPN5, C7, CACNG1, CAMLG, CAPN1, CAPN6, CAPS, CASP5, CASP10, RUNX2, CBL, CBLB, CCNF, CCNG2, CD3D, CD3E, CD3G, CD5, CD6, CD8A, CD28, CD86, TNFRSF8, TNFSF8, CD37, CD69, CD70, CD72, ADGRE5, CD151, CDA, CDK11B, CDH1, CDH6, CDH15, CDK3, CDK8, CDX2, CEBPE, CENPA, CENPB, CHD2, CHD4, CHEK1, CHKA, AP2M1, AP1S1, AP2S1, CLC, CLCN2, CLCN7, CLCNKA, CLCNKB, CLK1, CLK3, CLTC, CNN1, CNN2, COL15A1, COMP, COX8A, CLDN3, CR2, CRX, CRYBA1, CSH1, CSNK1D, CSNK1G3, CSNK2A2, CTF1, CTLA4, CTNNA1, CTNND1, CYP1A2, DAD1, DAZ1, BRINP1, DBP, DCT, DDX1, DDX5, DDX6, DDX11, DFFA, DHCR7, DIAPH2, DLX5, DMBT1, DNM1, DNMT1, DNMT3A, DNMT3B, DOK1, DPP4, DPYSL3, ARID3A, ATN1, DTNA, DTX1, E2F5, E2F6, E4F1, EBF1, EFNA3, EFNA4, EFNB1, EFNB2, EGR3, EGR4, EIF4A1, EIF4B, EIF4E, EIF4G2, EIF5, EIF5A, ELAVL2, ELF1, ELF3, ELK1, ELK3, EMD, ADGRE1, EMX2, EN1, EPRS, EPS15, EYA4, ERCC3, ERF, ERG, ESRRG, ETS2, ETV1, ETV3, ETV4, ETV6, EVX1, EWSR1, EXT2, EXTL3, EZH1, FABP7, FBLN2, EFEMP1, FCGR2A, FCGR2B, FCGRT, FCN2, GPC4, FGF11, GPC5, FOXD1, FLII, FLT3LG, FLT4, AFF2, FPR2, FPR3, CENPI, FUT8, ACKR1, FYB, GABRA4, GABRA5, GABRB2, GABRE, GABRG1, GABRR1, GABRR2, GAS1, GAS8, OPN1MW, GEM, GFRA1, B4GALT1, GH2, GLO1, GMDS, GNB2, GNG10, GNGT1, GNGT2, GNRH2, GNRHR, GPC1, GPM6A, GPR1, GPR3, GPR4, GPR15, GPR17, GPR19, LPAR4, GPR25, GRIA4, GRID1, CXCL2, CXCL3, GRPR, GSC2, GTF3A, BRF1, GUCY2C, GUCY2F, GUCY2D, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H2AD, HAS1, HAS3, HBA1, HBA2, HDGF, CFHR1, HIC1, HIVEP2, HLF, HMGN1, HMGA1, NR4A1, HMX2, HNF4G, ONECUT1, HNMT, HOXC10, HOXC11, HOXD4, HOXD8, HOXD9, HOXD10, HOXD12, HPGD, HPRT1, HSBP1, HSF4, DNAJB2, HSPA9, ICAM2, ICAM4, IDH1, SP110, IFIT3, IFNGR1, IFNW1, IGF2R, IGFBP6, RBPJ, IL1RAP, IL10RA, IL11RA, IL12RB2, IL13RA2, IL15RA, TNFRSF9, IL18, INCENP, IDO1, ING1, ING2, INPP1, INPPL1, INSIG1, INSRR, EIF3E, IRF5, ISG20, ITGA9, ITGAD, ITGAE, ITGB5, JARID2, JUNB, JUND, CD82, KCNA3, KCNA4, KCNJ3, KCNJ5, KCNJ6, KCNJ9, KCNJ14, KCNJ16, KLK2, KLRC3, KIF25, KRT4, LAMA3, LAMA4, LSP1, LTBP2, CAPRIN1, SMAD6, SMAD9, MAL, MAZ, MEOX2, MFGE8, SCGB2A1, MGAT3, CIITA, ATXN3, AFF1, FOXO4, CD200, CNOT2, NRF1, NTF4, NTHL1, NTN3, ODC1, OMD, OMP, OPA1, OR1F1, OR2C1, ORC1, ORC2, ORM2, OSBP, OTX1, OTX2, OVGP1, OVOL1, P2RY6, PA2G4, PAEP, REG3A, PAX3, PAX9, PCBP2, PCM1, CHMP1A, PDE8A, PDYN, PEG3, PENK, PEX13, CFP, PFDN2, PGAM1, PGR, ABCB1, PHF2, PIK3C2B, PI4KA, PIP4K2A, PPID, PPM1B, PPP2CB, PPP4C, PRCC, PRG2, PRKCSH, PRKX, PRSS8, PTGDR, PTGER1, PTGER2, PTH2R, PTPN14, PTPRE, PTPRR, PTPRZ1, PURA, PURB, PVR, PEX5, RAB5B, RAB6A, RAD21, RAD23B, RALA, RAP2A, RARB, RBBP4, RBBP6, RBBP8, RBM4, RBP2, OPN1LW, PRPH2, REG1A, DPF2, RFX1, RFX4, RFXAP, RGR, RHEB, RIT1, RLBP1, RLF, RNASE2, RPL6, RPL24, RPL28, RPL38, RPS3A, RPS6KB1, RPS6KB2, RPS26, RPS27, RRAS, RRM2, CLIP1, RTN2, RXRG, RYK, S100A4, S100A11, SALL1, TSPAN31, SAT1, SATB1, ATXN7, SCTR, CXCL6, CXCL5, SDC1, SEC14L1, TRAPPC2, SFPQ, SRSF5, SRSF7, SFSWAP, TRA2B, SH3BGR, SH3BGRL, SH3BP2, SHB, SHMT2, SIM2, SIX3, SKP2, SLA, SLC20A1, SMARCA1, SMARCA2, SMARCC1, SMARCE1, SUMO3, SIGLEC1, SNAI1, SNAPC3, SNAPC4, FSCN1, SNRPD1, SOX3, SOX5, SOX10, SP2, SPIB, SRP9, SRPK2, SRY, SSRP1, STAT2, STAT4, STAT6, STRN, STXBP2, STYX, SULT1A3, SUPV3L1, SURF4, T, TACC1, TAF4B, TAF10, TARBP1, TBL1X, TBP, GCFC2, ZNF354A, DYNLT3, PRDX2, NR2F1, KLF10, TSPAN7, TMPO, CLEC3B, TNNC2, TNFRSF1A, TNNI2, TOP1, TOP2A, TOP2B, NR2C1, NR2C2, TRHR, TRPS1, TSN, DNAJC7, TTC3, TTF1, TUFT1, TULP3, TYK2, TYROBP, UBA7, UBE2D2, UBE2E2, UBE3A, UPK1B, UCP1, UNG, KDM6A, UTY, VDAC1, VDAC2, VIM, EIF4H, LAT2, XPA, XRCC2, YY1, ZFP37, ZFPL1, ZFX, ZIC1, ZNF3, ZNF7, CNBP, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF33B, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF221, ZNF91, ZNF99, ZNF124, ZNF131, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF177, RNF112, ZNF180, ZNF189, ZNF208, ZNF214, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZXDA, PRDM2, PTP4A1, IL1R2, SCG2, AIMP2, FZD3, PDHX, CDK2AP1, MADCAM1, SF3A2, ZNF239, DPF1, CHAF1B, CLTCL1, USP9X, KDM5C, SMC1A, USP9Y, ARID1A, BAP1, CDC45, EOMES, FZD7, FZD9, GFI1B, HIST1H2AK, HIST2H2AC, OR1A1, OR1D5, OR1G1, OR3A3, SOX14, SPARCL1, UXT, ZNF282, UTF1, DYRK2, CUL4A, CUL2, ATRN, TTF2, TPST2, KLF11, SMARCA5, FKBP6, SORBS2, PPM1D, KCNAB2, HAT1, COPS3, API5, PIR, FCN3, BLZF1, STK16, RUVBL1, KLF7, UNC5C, SSNA1, EIF4EBP3, OASL, PTCH2, CHRD, NUMB, DDX3Y, EIF3F, EIF3G, EIF4G3, SRSF9, DNAH11, EED, CTNNAL1, HRK, TNFSF12, TNFSF9, TNFRSF18, DLK1, TNFRSF10D, CREG1, IL1RL2, IL18R1, CDKL1, SAP30, HESX1, NRP2, WISP3, AKAP4, PER3, VNN1, AP1M1, PHOX2B, FUBP3, HIST1H2AG, PGLYRP1, CDKL2, TAF1B, TAF1A, RNF8, TAAR5, UBA3, PSTPIP1, ANGPTL1, USP6, USP8, PDLIM1, SMC3, CBFA2T2, DYRK1B, CTDP1, IL1RL1, RASSF9, REPS2, DDX21, KCNAB3, DCLK1, ZMYM6, BMP15, PDLIM7, STK17B, STK17A, BCL7B, TAAR2, GPR52, ZNF235, COPS2, TRIP12, TRIP11, TRIP4, GLP2R, RAB33A, ZFYVE9, RECQL5, GRAP2, ZRANB2, ZNF264, FHL5, IL27RA, ONECUT2, ADAMTS3, LITAF, GDF15, TBPL1, GOSR1, TMEM59, BAG2, ZNF254, CIR1, CXCL14, SEC22B, GTPBP1, GOSR2, BRE, CDC42BPB, SOX13, RBM39, CREB5, MAD2L1BP, AKAP12, RNF14, RAB36, FEZ2, ZNF516, SAFB2, EIF5B, SDC3, PHF14, KDM4A, VGLL4, BZW1, CEP57, DHX34, ST18, ADAMTSL2, ZNF646, VPRBP, KNTC1, USP34, SETD1A, IFT140, ZNF536, ZFYVE16, SNX17, KIAA0586, DLGAP5, CKAP5, PHYHIP, TATDN2, SPOCK2, RNF40, CUL7, DNAJC6, ZBTB24, GAB2, C2CD5, ZNF518A, KIAA0319, TRIL, AREL1, RHOBTB1, SMG7, SNAP91, KLHL21, RBM19, FAM20B, RNF10, ZBTB5, P2RY14, RBM8A, DLEC1, NR1I3, FGFBP1, DMTF1, NR2E3, ZBTB33, TANK, PDCD6IP, FRAT1, HMGXB4, RANBP9, AP1M2, ABCC9, IL18BP, PTPRU, PDCD7, PQBP1, CTDSP2, ARL4A, ZNF263, TRAP1, YAF2, ARFRP1, G3BP1, TRIM28, WASF2, ZNF197, ZNF256, ALYREF, NUTF2, EIF1, OLIG2, PRG4, CTDSPL, CD96, STX6, STAM2, RAMP3 |
1848 | GO:0048193 | 0.04 | 1.32 | 60.87 | 73 | 208 | Golgi vesicle transport | APP, ARCN1, ARF1, ARF4, ARL1, BGLAP, CD59, AP1S1, CLTC, COPA, COPB1, CSNK1D, CD55, DYNC1H1, DNM2, EPS15, F2, F7, F10, FTL, GAS1, GOLGA2, GOLGA4, GOLGB1, GRIA1, INS, INSIG1, RAB8A, MYO1B, PPP6C, PRKCI, PRKD1, PROC, PROS1, RAB1A, RAB6A, SORT1, TRAPPC2, SNX2, SORL1, SPTA1, SPTB, UVRAG, AP3B2, CUL3, BLZF1, USO1, DYNLL1, VAMP8, SNAP23, PROZ, AP1M1, SEC22C, ZW10, VAPB, VAPA, COPB2, TRIP11, COG1, PICK1, GOSR1, SEC22B, GOSR2, CLINT1, PUM1, DNAJC6, SGSM2, GOLGA5, AP1M2, SCAMP2, ATP9A, ARFRP1, STX6 |
1849 | GO:1902532 | 0.03 | 1.31 | 65.12 | 78 | 223 | negative regulation of intracellular signal transduction | ABL1, ABL2, ARNTL, ATF3, BCL2L1, BMP4, CALM3, CASP8, CASQ2, CAV3, CD44, CD74, CDKN2D, CHAD, CLU, DCN, DDX3X, DUSP1, DUSP5, DUSP7, DUSP9, FBLN1, GCG, GP1BA, GPX1, GRINA, HMGCR, HSPB1, IGF1, IL10, ING2, INS, ITGB1, ITPR1, MEN1, OPA1, P2RX7, PHB, PPM1B, PPP2CB, PPP2R1A, PRKAA1, PTPN2, PTPN6, PTPRR, RASA2, SEC14L1, SMPD1, SNAI1, SOD2, SORL1, SPINK1, TP73, TPT1, TRIP6, TSC1, VDAC2, WFS1, CUL3, RIPK1, TNFSF14, VNN1, SOCS3, IL1RL1, ARHGEF2, ITGB1BP1, SOCS6, SLIT2, GSTO1, LITAF, BAG5, RASSF2, MFN2, NR1H4, RANBP9, TRAP1, RASA4, SPRY1 |
1850 | GO:0044265 | 0.00 | 1.31 | 167.59 | 199 | 574 | cellular macromolecule catabolic process | ARAF, ARNTL, BNIP3L, ZFP36L2, BUB1, BUB1B, CASP8, CAV3, CBL, CCNB1, CCNF, CDC20, CDC27, CDK2, CENPF, CLU, CSNK1D, CSNK2A1, CSNK2A2, CTSH, CTSK, CTSS, DDB1, DDX6, DUSP1, EIF4A1, EIF4A2, EIF4B, EIF4E, PTK2B, FAP, FAU, FEN1, GPC1, GPX1, UBE2K, DNAJB2, EIF3E, MAD2L1, SMAD7, ATXN3, CNOT2, CNOT4, OPHN1, PCBP2, EXOSC9, PPP1R8, PPP2CB, PPP2R1A, PPP2R2A, PPT1, DNAJC3, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB2, PSMB4, PSMB7, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD2, PSMD3, PSMD4, PSMD7, PSMD8, PSMD9, PSMD11, PTEN, PTK2, RAD23B, RB1, RBBP6, UPF1, RNASE2, RNASE3, RNASE6, RNF6, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RPS27A, SIAH2, SKP1, SKP2, SMARCC1, SUMO3, SUPV3L1, TBL1X, HSP90B1, TSG101, TTC3, TTK, UBB, UBA7, UBE2D1, UBE2D2, UBE2H, UBE2L3, UBE3A, SUMO1, UFD1L, USP4, WFS1, WNT1, TRIM25, ZNF207, RNF103, GAN, CLPP, USP11, USP9X, USP9Y, BAP1, CUL4A, CUL3, CUL2, CUL1, COPS3, PRPF18, KHSRP, RNASET2, CDC23, CTSF, RIPK1, CDC16, HERC2, RNF8, RPL14, USP14, USP6, USP2, USP8, ZW10, BUB3, AURKB, SOCS6, TRIP12, RPL23, UBE4A, PSMF1, BAG5, GTPBP1, NR1D1, CLOCK, RNF14, RNF7, UBE3C, DHX34, USP34, EIF4A3, DLGAP5, RNF40, CUL7, RGP1, AREL1, SMG7, KLHL21, RBM8A, USP3, RBX1, HDAC6, PDCD6IP, RNF41, PSME3, PSMD14, ZMPSTE24 |
1851 | GO:0044255 | 0.01 | 1.31 | 96.56 | 115 | 332 | cellular lipid metabolic process | ABCA1, ABCA4, ACAT1, ADH5, AGTR1, ALDH1A3, ALDH3A2, ANG, ARF1, ARSA, STS, ARSD, ARSE, ARSF, BAX, OPN1SW, SLC25A20, CAT, CAV3, CCNC, CD36, CHAT, AKR1C4, CHKA, CHKB, CLPS, CRH, CSF1R, CTGF, CYP3A4, DBI, EPHA8, PTK2B, FDFT1, FDPS, GPC4, FGF7, FGFR3, GPC5, FGR, FLT1, FLT3, G6PC, GATA6, OPN1MW, GK2, GPC3, GMDS, GPC1, GPD2, HEXA, HMGCR, HMGCS2, HTR2C, INPP1, INPPL1, KIT, LCAT, OCRL, OXCT1, P2RX1, P2RX7, PCK1, PCYT1A, PIK3C2A, PIK3C2B, PI4KA, PIP4K2A, PPP2R1A, PRKD1, PSAP, PTEN, PTK2, RAC1, RBP1, RBP2, OPN1LW, RLBP1, RXRA, CCL21, SDC1, SDC4, SFTPB, SLC12A1, SMARCD3, UAP1, SRD5A1, TAZ, TBL1X, UGT8, ZP3, LRP8, NSMAF, PIK3R3, DGKE, AGPS, DGAT1, B4GALT4, PEX11A, DPM2, INPP4B, SYNJ1, VAPB, VAPA, KLF4, GGPS1, PIGL, MPDU1, SDC3, RUBCN, PTDSS1, GNE, PIGK, COL4A3BP, DHRS9 |
1852 | GO:0022402 | 0.00 | 1.31 | 139.72 | 166 | 488 | cell cycle process | ACVR1B, ATR, BACH1, BBS4, BCL2L1, BMP4, BRCA2, BRDT, BUB1, BUB1B, CALM3, CAMK2A, CAMK2G, CCNE1, CCNF, CCNG2, CDK11B, CDC20, CDC25A, CDC25C, CDC27, CDK3, CENPE, CENPF, CHD4, CHEK1, CKS1B, CLTC, CSNK1D, CSNK2A1, CSNK2A2, CYP27B1, DAPK3, DDB1, DDX11, DHFR, DIAPH2, DNM2, E2F6, EIF4E, EML1, EMD, ENSA, EP300, ERCC3, ERCC4, FANCG, FGFR3, GEM, GOLGA2, GPR3, HGF, INCENP, ING2, ITGB1, KIF25, RAB8A, MEN1, MKI67, PPP1R12A, PPP1R12B, NUBP1, NUP98, ORC2, ORC4, OVOL1, PCM1, CHMP1A, ABCB1, PIM1, SEPT5, PPP2R1A, PPP2R2A, PPP5C, PPP6C, PRCC, PRKAR1A, PRKAR2B, PRKCB, PRKCQ, PTPN6, RAD21, RAD51, RAD51D, RALA, RAN, RANBP2, RBBP4, RBBP8, RPL24, RPS3, RPS6KA2, RPS6KB1, RRM2, CLIP1, STIL, SIX3, SKP1, SKP2, SMARCA4, SOX9, SOX11, ADAM17, DYNLT3, TOP2A, TOP2B, TPD52L1, TTK, TUBA4A, TUBG1, TYMS, UBE2D1, UBE2L3, UVRAG, VRK1, XRCC2, ZNF207, TUBA1A, NUP214, AAAS, CLTCL1, USP9X, KLF11, FKBP6, PPM1D, CDC14B, RUVBL1, SSNA1, DYNLL1, TNKS, PEA15, CDC23, CDC16, RNF8, USP8, LATS1, CCNB2, CTDP1, BUB3, RECQL5, CLOCK, BRE, MAD2L1BP, NUP155, CEP135, NUP93, CEP57, KNTC1, CKAP5, SFI1, CUL7, ARHGEF11, KIAA0196, KLHL21, DCLRE1A, REC8, PDCD6IP, PARP3, SMC4, CTDSP2, RAD50, KIF20A, FEM1B, ACTR1A, AKAP9, CTDSPL |
1853 | GO:0051726 | 0.05 | 1.30 | 56.88 | 68 | 200 | regulation of cell cycle | ARNTL, BAX, BBS4, BCR, CALM3, CCNE1, CCNG2, CDK11B, CDC25A, CDC25C, CDK3, CDK8, CENPE, CHAD, CKS1B, DAPK3, DCN, DDB1, E2F5, EP300, ERCC3, GP1BA, GPR3, ITGB1, JUN, JUNB, JUND, CHMP1A, PPP2R1A, PRKCQ, DNAJC3, PTCH1, PTPN6, RAD51D, RBBP4, RBL2, RPA3, SRSF5, SGK1, SIX3, SKP1, SKP2, SOX9, STAT3, STK10, DYNLT3, UVRAG, NUP214, BAP1, MADD, CDKL1, CDKL2, SOCS3, UBA3, DIRAS3, CCNB2, SOCS6, GMFG, PUM1, SLK, CUL7, KLHL21, OXSR1, PDCD6IP, PARP3, SAE1, RAD50, FEM1B |
1854 | GO:0034622 | 0.01 | 1.29 | 117.49 | 139 | 406 | cellular macromolecular complex assembly | ABL1, ADAR, ADD1, AP2B1, BIN1, ANG, ANGPT1, ARF1, ARHGAP6, ARL2, ATP6V0A1, ATR, BBS4, BICD1, CAPG, CASQ1, CASQ2, CAV3, CD3E, CD36, CIRBP, AP2S1, CLU, CLNS1A, COX15, CRYAB, CSNK1D, CYBA, DDX1, DDX3X, DDX6, DIAPH1, DIAPH2, DYNC1H1, EFNA5, CTTN, EPS15, PTK2B, FGA, GOLGA2, GRB2, GRB7, HCLS1, NRG1, HIP1, UBE2K, HSPA4, ICAM1, INSIG1, EIF3E, EIF6, IPO5, SMAD1, SMAD3, SMAD6, CNOT2, NUP98, PFN2, PIK3C2A, PRKCE, PSMD4, PSMD8, PSMD9, PSMD11, PTK2, RAB1A, RAC1, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL23A, RPL24, RPL38, RPS3, RPS19, RPS27, CLIP1, SCO1, CCL21, SRSF1, SRSF5, SFSWAP, SGK1, SNAP25, SNCA, SNRPC, SNRPD1, SNRPE, SNRPF, SPTA1, SPTB, SRPK2, TARBP2, TAZ, TBCD, GCFC2, TRAF2, TUBG1, USP4, UVRAG, VBP1, VDAC2, VIL1, WAS, ZNF207, SF3A2, PICALM, GAS7, PRPF18, EIF3F, EIF3G, SRSF9, SNAP23, SYNJ1, LATS1, PRPF3, SCAF11, SNAP29, SLIT2, ZFYVE9, DDX23, PICK1, BAG4, GMFG, PDE4DIP, NUP93, TOMM20, SNAP91, HDAC6, RANBP9, ARPC5, ARPC1B, ACTR3, ACTR2, ARPC2, AKAP9, ABI2 |
1855 | GO:1901135 | 0.01 | 1.28 | 152.64 | 179 | 526 | carbohydrate derivative metabolic process | ABCA1, ABO, ADCY1, ADCY7, ADCYAP1R1, AMPD1, ANGPT1, AQP1, ARCN1, ARF4, ARSA, STS, ARSD, ARSE, ARSF, ART1, ATP2B2, AVPR2, BAX, BMPR2, CACNB4, CALM3, CANX, CD44, CD59, CLTC, COL2A1, COL11A1, COPA, COPB1, CRH, CSNK1D, VCAN, CSPG4, DAD1, CD55, DCN, DYNC1H1, DRD3, DRD5, LPAR1, EDNRA, EDNRB, EXT2, EXTL1, EXTL3, PTK2B, GPC4, GPC5, FSHR, FUT6, FUT8, FZD2, G6PC, GALC, GALR1, GALNS, GCG, B4GALT1, GHRHR, GK2, GPC3, GM2A, GMDS, GNAS, GOLGA2, GOLGB1, GPC1, GPD2, GPLD1, GRIA1, GUCA1A, GUCA2A, GUCA2B, GUCY2C, GUCY2F, GUCY2D, HAS1, HAS2, HAS3, HEXA, HEXB, HGF, HTR2C, IDS, IDUA, IFNG, IHH, ITIH1, ITIH2, ITIH4, KIT, LIPC, MGAT2, MGAT3, MKI67, NUDT1, NTHL1, NTRK2, OMD, OVGP1, P2RY11, PALM, PDE4B, PDE8A, PFAS, CFP, PGD, PIM1, PPP6C, PRKCSH, PSAP, PTH, RAB1A, RAF1, RCVRN, RENBP, RPE, RRM1, RRM2, CCL21, SDC1, SDC4, TRAPPC2, SHMT1, SLC2A4, SLC9A1, SMPD1, SORD, UAP1, SPTA1, SPTB, UGT8, UNG, VEGFA, VEGFB, VIP, VIPR2, WFS1, TUSC3, USO1, PDE5A, DYNLL1, TNKS, GALNT4, B4GALT4, B4GALT3, B3GALT2, DPM2, MBD4, PGLYRP1, COPB2, B4GALT6, COG1, CHST3, AKAP6, PIGL, TBPL1, MPDU1, GOSR1, TMEM59, SEC22B, GABBR2, GOSR2, AKAP12, GUCA1C, HS2ST1, SDC3, PTDSS1, SPOCK2, XYLB, HS3ST3B1, HS3ST1, GNE, PIGK, PARP3, ABCC5, UST, CHST4 |
1856 | GO:0000278 | 0.04 | 1.28 | 73.01 | 86 | 257 | mitotic cell cycle | ASCL1, BBS4, CCNF, CCNG2, CDK11B, CENPA, CLTC, DAPK3, DNMT3A, E2F5, E4F1, EML1, FEN1, CENPI, GEM, GOLGA2, HGF, INCENP, KIF25, MEN1, NUP98, CHMP1A, PPP5C, PRKCB, PTCH1, RAB1A, RAD21, RAN, RANBP2, RANGAP1, RBL2, RFC1, RFC3, RFC4, RFC5, RNF2, RPS3, RPS27, RRM1, CLIP1, SET, STIL, STK10, DYNLT3, DYNLT1, XRCC2, NUP214, AAAS, CLTCL1, USP9X, HIST1H4I, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, BLZF1, RUVBL1, USO1, RNF8, UBA3, USP8, SMC3, ARHGEF2, AURKB, KIF3B, RECQL5, BRE, NUP155, NUP93, SLK, CUL7, GINS1, KLHL21, DCLRE1A, OXSR1, USP3, PARP3, SMC4, SAE1, RAD50, KIF20A, SPRY1 |
1857 | GO:0048609 | 0.03 | 1.27 | 87.68 | 103 | 305 | multicellular organismal reproductive process | ACOX1, ADA, ADCYAP1R1, NR0B1, BIRC3, ATRX, BAD, BBS4, BIK, BRCA2, BRDT, CCNB1, CDC25C, COMT, CXADR, CYLC1, CYLC2, DAZ1, ACE, DIAPH2, DLD, DNM2, DNMT3A, EDNRB, PHC2, CELSR2, ETV5, PTK2B, GATA4, GHRHR, HIST1H1T, HIST1H1A, HPGD, IGF1, IGF2R, IL1R1, ING2, KRT9, LIMK2, SMAD1, ODF1, CLDN11, OVOL1, P2RX1, P2RY2, SERPINA5, PPP2R1A, PRKACG, PRKAG1, PRM2, RAD23B, RAD51C, RARA, RNF2, RPS6KA2, RPS6KB1, SBF1, SLC6A4, SMARCA2, SMARCA4, SOX3, SOX9, SP1, SP3, SPAG4, STYX, TAF4B, TARBP2, TBP, NR2C2, TSPY1, VIP, YY1, ZNF35, ZNF148, FOSL1, IFT88, USP9X, USP9Y, FKBP6, DDO, RUVBL1, TP63, PDE5A, DYNLL1, EIF2S2, HERC2, RNF8, RGN, FAM50A, PICK1, ADAMTS2, TBPL1, CLOCK, SPAG6, PUM1, CEP57, UTP14C, SPATA2, KIAA0196, REC8, BCL2L11, AKAP9 |
1858 | GO:0044238 | 0.00 | 1.27 | 507.62 | 566 | 2036 | primary metabolic process | ABCA3, ABCA4, ACADM, ACADS, ACAT1, ACOX1, ACP1, ACP2, ACPP, ACTB, ACY1, ADA, ADAM10, ADD1, ADH5, ADPRH, ADRBK1, ADSS, AHCY, AK1, AK2, ALAS2, ALB, ABCD1, ALDH1A3, ALDH3B2, ALDH3A2, ALOX15B, AMPD1, AMPD2, SLC25A4, APOF, APRT, KLK3, TRIM23, ARG1, ARG2, ARSA, STS, ARSD, ARSE, ARSF, ASL, ASNS, ASPA, ASS1, ATP1A2, ATP2B2, ALDH7A1, ATP5C1, ATP5E, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP6V1B2, ATP6V0A1, AUH, AXL, BCAT2, BCHE, BCKDHA, OPN1SW, BCR, BGLAP, BICD1, BLK, BMX, BNIP3L, BYSL, CAPN5, DAGLA, CACNB4, SLC25A20, CAPN1, CAPN6, CASP5, CASP10, CBR1, CCNF, ENTPD2, CDK3, CDK6, CDO1, CHAT, AKR1C4, CHKA, CHKB, CHRM1, CHRM3, TBCB, CKM, CLCA1, TPP1, CLNS1A, CLPS, CNP, COL2A1, COL11A1, COX6A1, COX6B1, COX7B, COX7C, COX8A, COX15, CPA1, CPT1B, CPT2, CR2, CRAT, CSNK1G3, CSTF3, CTNS, CTRB1, CTSE, CTSK, CTSS, CYP1A2, CYP2A6, CYP2A13, CYP2F1, CYP3A4, CYP8B1, CYP11B1, DAO, DARS, DBI, DBT, DCT, DDB1, DHX8, DDX10, DDX11, DFFB, DHODH, DHPS, DMBT1, SARDH, DNASE1, DNASE1L1, DNASE1L2, DNASE1L3, TRDMT1, DNTT, DPH2, DPP4, DPP6, TYMP, ECH1, PHC2, EEF1B2, EHHADH, EIF1AX, SLC29A1, EPHA3, EPHB2, EPHB3, ETFA, ETFDH, EVPL, EXTL3, F7, F10, FAAH, FABP2, FABP7, FANCE, FANCB, FANCF, FANCG, FAP, FAU, FCN2, FDFT1, FDPS, FEN1, FKBP3, FKBP5, FYB, GAD1, GARS, GATM, OPN1MW, GFER, GGT7, GLDC, GLUD1, GP9, GPT, GPX2, GSS, GSTZ1, GTF3C1, GTF3C2, GUCY2C, GUCY2F, GUK1, GZMH, GUCY2D, GZMK, HADHA, HARS, CFHR1, HLCS, HMBS, HMGCS2, HNMT, HP, HPD, HPGD, HSD11B1, HSD17B3, HSD17B4, HSPA9, IAPP, IGFBP6, IL1RAP, IL1RN, IL12RB2, IMPDH1, IMPDH2, INCENP, IDO1, INSRR, ISG20, EIF6, IVD, IVL, KCNH2, KCNQ1, KLK1, KLK2, LCAT, LIMK2, LIPA, LIPC, LIPE, LTA4H, MFGE8, MKI67, NUDT1, DRG1, CNOT4, NTHL1, OAT, OCRL, OLR1, ORC4, OXCT1, OXTR, P4HA1, PAH, PCBP2, PCMT1, PCSK5, PCYT1A, PDE4B, PEPD, PEX7, PEX12, PEX13, PFAS, PFDN2, PGA5, PIK3C2A, PIK3C2B, PI4KA, PIP4K2A, EXOSC9, PPIB, PPM1B, PPP2CB, PPT1, PRCP, PREP, PRIM2, PRKG1, PRKX, PRL, PROC, PRPS2, PRPSAP1, PRSS8, KLK10, PSKH1, PSPH, PTGDR, PTGS1, PTMA, PTMS, PTPN4, PTPN7, PTPN9, PTPN12, PTPRE, PTPRH, PTPRN, PTPRN2, PTPRS, ABCD3, PYCR1, QARS, QDPR, RAB3B, RAB6A, RAB27A, RABGGTA, RABGGTB, RAD51C, RAD51B, RAD51D, RAG2, RANGAP1, RBMS1, RBMS2, RBP1, RBP2, OPN1LW, REV3L, RFC3, RFC4, RFC5, RGR, RGS12, RHEB, RLBP1, RNASE1, RNASE2, RNASE3, RNASE6, RP9, RPA3, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL36AL, RPL37, RPL37A, RPL39, RPL36A, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS27, RRM1, ACSM3, SBF1, SRSF1, SRSF5, SFTPB, SHMT1, SHMT2, SLC6A6, SLC6A8, SLC7A4, SLC10A1, SLC12A1, SLC34A1, SLCO1A2, SMS, SNRPA, SNRPA1, SNRPC, SNRPD1, SNRPE, SNRPF, SPG7, SPRR2A, SPRR2D, SPRR2E, SPRR2G, SPRR3, SQLE, SRD5A1, SRP14, SSR3, ST14, SULT1E1, ELOVL4, SULT1A3, SULT1C2, SULT2B1, SUOX, TAT, TAZ, TBCD, TBCE, PRDX2, TOP1, TOP2B, TPMT, TPSAB1, TRIO, TSN, TTC3, TUBA4A, TUFM, TYK2, TYR, TYRO3, UBA7, UBE2E2, UBE2H, UFD1L, UPP1, UQCRC1, UQCRC2, UQCRH, KDM6A, UTY, VBP1, TRPV1, VRK1, WRN, XPA, XPNPEP1, XRCC2, YWHAZ, PTP4A1, RNF103, TUBA1A, SCG2, SLC25A16, GAN, SLC7A5, SF3A2, CLPP, USP11, RBM10, KDM5D, ACOX3, BAP1, DUSP11, TPST2, TPST1, FKBP6, PPM1D, KCNAB2, DGKE, DDO, CYP4F2, COPS3, AGPS, PRPF18, RRP1, RDH16, RNASET2, DDX3Y, ALDH4A1, DGAT1, ABCC3, CTSF, ADAM19, ADAM15, RIOK3, DYRK4, PEX11A, CDKL1, INPP4B, ALKBH1, PROZ, SGPL1, EIF2S2, HERC2, MBD4, KYNU, P4HA2, CDKL2, SLC25A14, RPL14, USP6, USP8, ATP6V0D1, PRPF3, EXO1, PCSK7, SCAF11, DDX21, DCLK1, VAPA, STK17B, STK17A, GTF3C5, GTF3C4, GTF3C3, EFTUD2, RPL23, UBE4A, ZFYVE9, COX5A, TMPRSS11D, SNRNP40, DDX23, GGPS1, PICK1, PIGL, ADAMTS4, ADAMTS3, ADAMTS2, BAG2, TP53I3, CHD1L, CDC42BPB, PREPL, ENTPD4, RNF7, KLK4, AATK, SNCAIP, TTLL4, UBE3C, KIAA0391, ADAMTSL2, UTP14C, SNX17, DHX38, SPCS2, PTDSS1, TATDN2, TOMM20, SCRN1, SPOCK2, CUL7, DNAJC6, GINS1, AREL1, SMG7, KLHL21, JOSD1, DCLRE1A, USP3, REC8, PDCD6IP, PIGK, SH2D3C, SH2D3A, UBA2, SAE1, DPP3, PTPRU, PDCD7, COL4A3BP, SGK2, G3BP1, SUGP2, ABI2, SLC25A15, DHRS9, DHRS2, ZMPSTE24 |
1859 | GO:0044271 | 0.04 | 1.27 | 74.89 | 88 | 281 | cellular nitrogen compound biosynthetic process | ACADM, SLC25A4, ARG1, ARG2, ASL, ASNS, ASS1, ALDH7A1, SLC25A20, CDK4, CIRBP, CPS1, SLC25A10, DARS, DAZ1, DDX6, DHPS, EEF1B2, EIF1AX, EIF2B1, EIF4A1, EIF4B, EIF4E, EIF4EBP2, EIF4G2, EIF5, EIF5A, ELAVL1, EPRS, GAPDH, GGT7, GRB7, GSS, HARS, HSPB1, EIF3E, IREB2, ITGA2, EIF6, CAPRIN1, OAZ1, OAZ2, ODC1, P2RX1, P2RX4, P2RX7, PCSK5, PPP1CA, DNAJC3, PTGS2, QARS, QDPR, RBM4, UPF1, RPL36AL, RPS6KB1, RPS6KB2, SAT1, SMPD1, SMS, SRP9, SRP14, SSR3, TUFM, UGT8, TRPV1, EIF4H, AIMP2, SLC25A16, NSMAF, SLC25A12, EIF4EBP3, DDX3Y, EIF3F, EIF3G, EIF4G3, EIF2B3, EIF2B2, EIF2S2, SLC25A14, GTPBP1, EIF5B, PUM1, EIF4A3, SPCS2, TRAP1, SLC25A15, EIF1 |
1860 | GO:0009059 | 0.01 | 1.26 | 166.75 | 193 | 609 | macromolecule biosynthetic process | ABCA1, ABO, ALAS2, ANGPT1, SLC25A4, ARCN1, ARG1, ART1, SLC25A20, CANX, CD59, CDC25A, CDC25C, CDKN2D, COPA, COPB1, COX6A1, COX6B1, COX7B, COX7C, COX8A, CSNK1D, VCAN, CSPG4, SLC25A10, CSTF3, DAD1, CD55, DARS, DDB1, DHPS, DYNC1H1, DNTT, TYMP, EEF1B2, EIF1AX, EXTL1, EXTL3, FAU, FEN1, GPC4, GPC5, FUT6, FUT8, GARS, B4GALT1, GMDS, GOLGB1, GPC1, GPI, GPX2, GRIA1, GTF3C1, GTF3C2, HARS, HEXA, EIF6, LCAT, LIPC, MGAT2, MGAT3, DRG1, NUP98, OMD, ORC4, PRDX1, CFP, PPM1B, PPP5C, PPP6C, PRIM2, PRKAB2, PRKAG1, PRKCSH, PTMA, PTMS, QARS, RAB1A, RAD51, RANBP2, RBMS1, REV3L, RFC3, RFC4, RFC5, RGS12, RHEB, RPA2, RPA3, RPL3, RPL3L, RPL5, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL36AL, RPL37, RPL37A, RPL39, RPL36A, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RRM1, SDC1, SDC4, SETMAR, SRSF1, SRSF5, SRSF7, SLC2A4, SNRPE, SNRPF, UAP1, SPTA1, SPTB, SRP14, SSR3, PRDX2, TOP1, TUFM, UBA7, UFD1L, VEGFB, WRN, YWHAZ, AIMP2, TUSC3, NUP214, SLC25A16, AAAS, CDK2AP1, CUL4A, SLC25A12, USO1, DDX3Y, SRSF9, GALNT4, B4GALT4, B4GALT3, B3GALT2, DPM2, EIF2S2, SLC25A14, RPL14, DDX21, COPB2, GTF3C5, GTF3C4, GTF3C3, B4GALT6, RPL23, COX5A, COG1, CHST3, ATG5, PIGL, ADAMTS3, GOSR1, SEC22B, GTPBP1, GOSR2, NUP155, HS2ST1, SDC3, NUP93, DHX38, SPCS2, GINS1, HS3ST3B1, HS3ST1, GNE, PIGK, PARP3, ABCC5, UST, RAD50, CHST4, SLC25A13, SLC25A15 |
1861 | GO:0006325 | 0.04 | 1.24 | 94.66 | 109 | 326 | chromatin organization | ACTB, ACTL6A, APBB1, RERE, BMI1, BRCA2, BRDT, CCNB1, CDK2, CDK4, CHD2, CHD4, CHEK1, DAPK3, DDB1, DNMT1, DNMT3A, DNMT3B, EP300, EYA4, EYA2, EZH1, GATA3, GCG, KAT2A, HIST1H2AD, HLCS, HMGN1, FOXA2, HNRNPC, PRMT1, HSF4, ING1, ING2, ISL1, JARID2, MEN1, PAX3, PHB, PHF2, PPP5C, PRKAA1, PRKCB, PRKD1, MAPK3, RAG1, RAG2, RB1, RBL2, REST, RNF2, SALL1, SATB1, ATXN7, SETMAR, SFPQ, SKP1, SMARCA1, SMARCA2, SNCA, SREBF1, SUPV3L1, TAF7, TAF10, TBL1X, TBP, TOP1, TRPS1, TTF1, KDM6A, UTY, VEGFA, VRK1, PRDM2, KDM5C, KDM5D, BAP1, CDC45, GFI1B, HIST1H2AK, HIST2H2AC, OGT, IKBKAP, TP63, EED, SAP30, HIST1H2AG, RPS6KA4, TAF1B, TAF1A, RNF8, AURKB, RPS6KA5, TRIP12, HMGN3, GTF3C4, ATG5, CHD1L, CLOCK, BRE, PPM1F, KDM4A, VPRBP, USP34, SETD1A, RNF40, USP3, NR1H4, HDAC6 |
1862 | GO:0009058 | 0.00 | 1.23 | 452.81 | 508 | 1688 | biosynthetic process | ABCA2, ABL1, ABO, ACTN4, ACTL6A, ACTN1, ACVR2B, AEBP1, AES, ALX3, SLC25A4, ANXA4, APBB2, XIAP, BIRC5, ARCN1, ART1, ASCL2, PRDM1, BMI1, BMP1, BMP8B, ZFP36L2, KLF9, BTF3, DAGLA, CACNA1A, SLC25A20, CANX, CBL, CD36, CD59, CDK11B, CDC6, CDC25A, CDC25C, CDK5, CDKN1A, CDKN2D, CENPB, CENPF, CHD2, CHD4, CKM, CMKLR1, COMT, COPA, COPB1, COX6A1, COX6B1, COX7B, COX7C, COX8A, CRY2, CSNK1D, CSNK2A1, CSNK2A2, CSTF3, CTNND1, CTNND2, DAD1, CD55, DAO, DAPK3, DARS, DBH, DDX1, DDX6, DIO1, DYNC1H1, DNMT1, DNMT3A, DNMT3B, DNTT, ATN1, RCAN1, TSC22D3, DTX1, DUSP1, E2F6, E4F1, ECM1, EEF1B2, EFNA1, CELSR2, EGR3, EGR4, EIF1AX, EIF2B1, EIF4A1, EIF4A2, EIF4B, EIF4E, EIF4EBP2, EIF4G2, EIF5, ELAVL2, EMX1, EMX2, EPRS, EYA4, ERF, ERG, ETV3, EWSR1, EYA2, FAU, FBN1, EFEMP1, FGF8, FGF9, FGFR3, FOXD1, FLII, FUT6, GDF9, GHSR, GK2, GLO1, GOLGB1, FFAR3, GPX2, GRB7, GRIA1, GSC2, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, H3F3B, HBE1, HDGF, HIC1, HIP1, HIVEP2, HLF, HMX2, HOXC10, HOXD4, HOXD12, HSBP1, ID1, SP110, IL1RAP, IL18, INHA, EIF3E, IREB2, ITGAV, EIF6, JARID2, KCNK2, CAPRIN1, SMAD6, MAZ, MGAT3, ATXN3, NUBP1, DRG1, TONSL, CNOT2, NTRK3, NUP98, OAZ1, OAZ2, ORC1, ORC2, ORC4, OVOL1, PA2G4, PRDX1, PAM, CHMP1A, PCSK5, PDE8A, PDPK1, PEG3, CFP, PIM1, PPID, PPM1B, PPP1R8, PPP2R1A, PPP5C, PPP6C, PRG2, PRKAR1A, PRKCSH, PTMA, PTMS, PTPN14, PURA, PURB, QARS, QDPR, RAB1A, RAD51, RBBP4, RBBP6, RBBP8, RBL2, RBM4, RBMS1, DPF2, RFX1, RGS12, RHEB, RNF2, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL36AL, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3A, RPS4Y1, RPS6, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RYR2, S100A1, S100A11, SAT1, SATB1, XCL1, TRAPPC2, SET, SETMAR, SFPQ, SFRP5, SRSF1, SRSF5, SRSF7, SFSWAP, SFTPD, SGK1, SIAH2, SIM2, SLC2A4, SLC22A2, SMARCE1, SMS, SNAPC3, SNAPC4, SNRPE, SNRPF, SOD2, SOX3, SP2, SPIB, SPTA1, SPTB, SRP9, SRP14, SSR3, STAT2, TAF4B, TAF10, TARBP1, TAT, GCFC2, ZNF354A, PRDX2, KLF10, TMPO, TOP1, NR2C1, TRIP6, TSC1, TSG101, TTF1, TULP3, TNFSF4, UBE2D1, UBE2D2, UBE2L3, SUMO1, UCP1, SCGB1A1, UGT2B7, VAV1, VEGFB, EIF4H, WRN, XRCC5, YWHAZ, ZFP37, ZFPL1, ZFX, ZNF3, ZNF7, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF33B, ZNF35, ZKSCAN1, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF221, ZNF91, ZNF99, ZNF124, ZNF131, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, ZNF154, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF208, ZNF214, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, PRDM2, AIMP2, TUSC3, NUP214, SLC25A16, AAAS, CDK2AP1, ANP32A, ZNF239, DPF1, CHAF1B, USP9X, KDM5C, USP9Y, HIST1H4I, FZD6, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, SOX14, UXT, ZNF282, NR0B2, CUL3, CUL2, TTF2, KLF11, SMARCA5, IKBKAP, HAT1, GAS7, PIR, FCN3, BLZF1, KHSRP, RGS20, RUVBL1, USO1, EIF4EBP3, CHRD, DDX3Y, DYNLL1, EIF3F, EIF3G, EIF4G3, SRSF9, GALNT4, EED, CREG1, SAP30, HESX1, PER3, TAX1BP1, EIF2B3, EIF2B2, EIF2S2, HIST1H3F, HIST1H2AG, TAF1B, TAF1A, SLC25A14, RNF8, UBA3, RPL14, USP2, PDLIM1, DDX21, BMP15, COPB2, ZNF235, COPS2, TRIP11, GTF3C5, GTF3C4, GTF3C3, RPL23, COX5A, COG1, RECQL5, ZRANB2, ZNF264, ATG5, LITAF, GOSR1, TMEM59, ZNF254, CIR1, SEC22B, GTPBP1, GOSR2, SOX13, RBM39, NUP155, PPM1F, SAFB2, EIF5B, PHF14, KDM4A, VGLL4, NUP93, BZW1, PUM1, ST18, ZNF646, VPRBP, USP34, SETD1A, ZNF536, ZFYVE16, DHX38, SPCS2, RB1CC1, ZBTB24, ZNF518A, ZBTB5, RBM8A, DMTF1, CASP8AP2, ZBTB33, PARP3, ABCB6, PQBP1, ZNF263, TRAP1, CHST4, ZNF197, ZNF256, EIF1, OLIG2, PRG4, DENND4A, IRX5, RAMP3 |
1863 | GO:0006996 | 0.00 | 1.22 | 368.24 | 413 | 1289 | organelle organization | ABL2, ACP2, ACTB, ACTN4, ACTN1, ADD1, ABCD1, ANG, SLC25A4, ANXA5, APBB1, ARF4, RND3, ARHGAP4, ARHGAP6, ARHGDIB, ARL1, RERE, ATP2A1, ATP2B2, BCL2A1, BCL2L1, BCR, BICD1, BLK, BMI1, BNIP3L, DST, BST2, TSPO, CAMK2A, CAPG, CAPN6, CAPS, CASQ1, CASQ2, CDK4, CENPA, CHD2, CHD4, CIRBP, CLU, TPP1, CLN5, CNGA2, CNN1, CNN2, CNN3, CNP, COX8A, CRYAB, CSF1R, CTNNA1, CXADR, DBN1, DDB1, DDX1, DDX3X, DDX6, DDX11, DFFB, DIAPH1, DIAPH2, DNM1, DYNC1H1, DNM2, DNMT3A, DPYSL3, TYMP, S1PR1, EFNA5, CELSR2, EML1, EMD, EMP2, EP300, EPB41, EPB41L2, EPHA3, EPHA5, EYA4, ERCC3, ETS1, EYA2, EZH1, FANCF, FANCG, FEN1, FGD1, FGF7, FLII, CENPI, IFI6, GAA, GABRA5, GAPDH, GATA3, GFAP, GFER, GHSR, GOLGB1, GPM6B, GPX1, GRB7, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1T, HIST1H2AD, HIST1H2BB, H3F3B, HIST1H1A, HARS, HEXB, HHEX, HK2, HLCS, HMGN1, HMGA1, FOXA2, ONECUT1, HNRNPC, HRG, PRMT1, HSF4, HSPA4, HSPA9, IDUA, ILK, ING1, INPPL1, INSRR, ITGB1, EIF6, ITGB5, JUN, JUP, KCNK3, KISS1, KIT, KRT4, KRT9, KRT13, KRT14, KRT16, LLGL2, MAP1B, MEN1, ATXN3, MYO1B, NUBP1, NRF1, NTHL1, NUP98, OCRL, OPHN1, P2RX5, PALM, PAM, PAX3, PCM1, PCNA, PDPK1, PEX1, PEX6, PEX7, PEX10, PEX12, PEX13, PGK2, PHB, PHF2, PPID, PPP2CB, PPP2R2A, PPT1, PRIM2, PRKAA1, PRKAB2, PRKAG1, PRKAR2B, PRKCB, PRKG1, PRM2, PTGFRN, PTK2, PURA, ABCD3, PEX5, RAB5B, RAB27A, RAC3, RAD23B, RAF1, RAG1, RAG2, RALA, RANBP2, RAP2A, RBBP4, RBL2, UPF1, REST, RFC1, RFC3, RFC4, RFC5, RFX3, RFX4, RLF, RNF2, RPGR, RPA2, RPA3, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL23A, RPL38, RPS19, RPS27, RPS27A, S100A8, S100A9, SALL1, SATB1, ATXN7, SET, SETMAR, SGK1, SHC1, STIL, SIPA1, SKP1, SLC9A1, SLCO1A2, SLC22A3, SMARCA1, SMARCA2, SMARCC1, SMARCD3, SMARCE1, SNCA, SNRPD1, SNRPF, SOD2, SOX9, SP100, SPAG4, SPG7, SPTA1, SPTB, SRF, SRPK2, STAT2, STAT3, SUPV3L1, TACC1, TAF7, TAF10, CNTN2, TAZ, TBCD, TBCE, TBL1X, TBP, TOP1, NR2C2, HSP90B1, TRPS1, TSC1, TSPY1, TTF1, TUBA4A, TUBG1, TUFM, SUMO1, UGT8, CLRN1, KDM6A, UTY, VDAC1, VIM, WRB, WRN, XRCC5, YY1, ZNF189, PRDM2, TUBA1A, AAAS, IFT88, GAN, CHAF1B, KDM5C, KDM5D, ARID1A, HIST1H4I, CDC45, GFI1B, HIST1H2AK, HIST2H2AC, HIST1H2BL, HIST1H2BN, HIST1H2BM, HIST1H2BF, HIST1H2BH, HIST1H2BO, HIST2H2BE, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, UXT, CUL4A, SMARCA5, SORBS2, CNTNAP1, IKBKAP, HAT1, GAS7, COPS3, BLZF1, TP63, SSNA1, SAP30, AKAP4, ARHGEF7, HIST1H3F, HIST1H2AG, TAF1B, TAF1A, BAZ1B, USP8, ATP6V0D1, ZMYM6, PDLIM7, CYTH2, COPS2, TRIP12, TRIP11, TRIP10, HMGN3, GTF3C4, SLIT2, RAB33A, SLC9A3R1, NRXN1, NRXN2, COG1, PEX16, EIF2AK3, CHST3, ONECUT2, BAG5, CHD1L, BCAR1, CLOCK, CDC42BPB, NUP155, FEZ2, CEP135, KDM4A, NUP93, KIAA0391, CROCC, RUBCN, USP6NL, SEMA3E, VPRBP, USP34, SETD1A, IFT140, SLK, RIMS3, KIAA0586, PHYHIP, TOMM20, SFI1, RB1CC1, ARHGEF11, GINS1, CEP350, MFN2, GOLGA5, USP3, NR1H4, RBX1, FGFBP1, HDAC6, PARP3, RANBP9, COL4A3BP, KIF20A, ACTR1A, FRY, AKAP9, G3BP1, WASF2, SPRY1, STAM2, ABCC4, ZMPSTE24 |
1864 | GO:0090304 | 0.00 | 1.21 | 631.40 | 695 | 2216 | nucleic acid metabolic process | ABCA2, ACTN4, ACTN1, ACVR1B, ACVR2B, ADAM8, ADAR, AEBP1, AES, AGTR2, NR0B1, AHR, ALK, ALX3, ANG, ANXA4, APBB2, XIAP, BIRC5, APP, ARF4, PHOX2A, ARNT, ARNTL, ASCL1, ASCL2, ATF3, ATF4, RERE, BCL3, BCL9, BICD1, PRDM1, BMI1, BMP1, BMP3, BMP8B, BMPR1A, BRDT, ZFP36L2, KLF9, KLF5, BTF3, BTK, BYSL, CAMK2A, CAT, RUNX2, CBL, CCNB1, CCNC, CCNT2, CD3D, CD86, TNFSF8, CD36, CDK11B, CDH1, CDK5, CDK8, CDX2, CEBPE, CENPB, CHD2, CHD4, CHUK, CLU, CLK1, CLK3, CLNS1A, CMKLR1, COL1A1, COX6A1, COX6B1, COX7B, COX7C, COX8A, CREB1, CRX, CRY2, CSNK2A1, CSNK2A2, CSTF3, CTH, CTNND1, CTNND2, DAPK3, DARS, DBP, DCN, DDX3X, DDX5, DDX6, DHX8, DDX10, DHFR, DLX5, DNM2, DRD3, ARID3A, ATN1, RCAN1, TSC22D3, DTX1, E2F5, E2F6, EBF1, ECM1, EDA, S1PR1, EDNRB, EFNA1, CELSR2, EGR2, EGR3, EGR4, EIF4A1, EIF4A2, EIF4B, EIF4E, ELAVL2, ELF1, ELF3, ELK1, ELK3, EMX1, EMX2, EN1, EPHA5, EPRS, ERF, ERG, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, EZH1, F2R, FAU, FBN1, EFEMP1, FGF4, FGF7, FGF8, FGF9, FGFR3, FOXD1, FLII, AFF2, FSHB, NR5A2, FZD2, GALR1, GARS, GATA3, GATA4, GATA6, GCG, KAT2A, GDF9, GDNF, GPC3, GLO1, GPI, GPX2, GSC2, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H1B, HIST1H2AD, HARS, HAS3, HBE1, HCLS1, HDGF, HEXB, NRG1, HHEX, HIC1, HIP1, HIVEP2, HLF, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD4, HOXD8, HOXD9, HOXD10, HOXD12, HPN, PRMT1, HSBP1, HSF4, ICAM1, ID1, ID2, IFI16, SP110, IFNA2, IGF2, IHH, IL1A, ILK, ING2, INSIG1, EIF3E, IRAK1, ITGA6, IRAK2, IRF1, IRF5, ISL1, JARID2, JUNB, JUND, JUP, KIT, LMO1, LTF, SMAD1, SMAD3, SMAD6, SMAD7, SMAD9, MAZ, MEOX2, CIITA, AFF1, FOXO4, PPP1R12A, DRG1, CNOT2, CNOT4, NRF1, YBX1, NTRK3, DDR2, OAS1, OAS3, OTX1, OTX2, OVOL1, PA2G4, PRDX1, SERPINE1, PAM, PAX2, PAX3, PAX9, PCBP2, PCK1, CHMP1A, PDE8A, PDPK1, PEG3, PGR, PHF2, PIM1, EXOSC9, PPID, PPP1R8, PPP2R2A, PRKAA1, PRKAB2, PRKAG1, PRKAR1A, PRKCB, PRKCI, PRKD1, PROX1, PSMA6, PSMC1, PSMC2, PSMC3, PSMC4, PSMC5, PSMD9, PTAFR, PTCH1, PTEN, PTGIS, PTH, PTMA, PTPN14, PURB, QARS, RAF1, RANBP2, RARA, RARB, RB1, RBL2, RBM4, RBMS2, DPF2, REST, RET, RFX1, RFX3, RFX4, RFXAP, RGS12, RHEB, RNASE1, RNASE2, RNASE3, RNASE6, RNF2, RNF6, RP9, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL37, RPL37A, RPL38, RPL39, RPL36A, RPS3A, RPS4Y1, RPS6, RPS6KA1, RPS6KA3, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, RXRA, RXRG, RYR2, S100A1, S100A8, S100A9, S100A12, SALL1, SATB1, ATXN7, XCL1, TRAPPC2, SFRP5, SRSF1, SRSF5, SRSF7, SFSWAP, TRA2B, SGK1, SIAH2, SIM2, SIX3, SLC9A1, SMARCA2, SMARCA4, SMARCC1, SMARCD3, SMARCE1, SNAI1, SNAPC3, SNAPC4, SNCA, SNRNP70, SNRPA, SNRPA1, SNRPC, SNRPD1, SNRPE, SNRPF, SOD2, SOX3, SOX4, SOX5, SOX9, SOX10, SOX11, SP1, SP2, SP3, SPIB, SREBF1, SRF, SRPK2, SRY, TRIM21, STAT2, STAT3, STAT4, STAT5B, SYK, T, TAF4B, TAF7, TAF10, TAL1, TARBP1, TARBP2, TBL1X, TBP, HNF1A, GCFC2, ZNF354A, PRDX2, NR2F1, NR2F2, KLF10, NR2E1, TMPO, TNFRSF1A, TNNI2, NR2C1, NR2C2, TRAF1, TRAF2, TRIP6, TRPS1, TSC1, TSG101, TULP3, UBE2D1, UBE2D2, UBE2L3, UBE3A, UCP1, SCGB1A1, USP4, NR1H2, USF1, VAV1, VDR, VEGFA, WFS1, WNT1, WNT11, YWHAH, YWHAZ, ZFP37, ZFPL1, ZFX, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF33B, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF221, ZNF99, ZNF124, ZNF131, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, ZNF148, ZBTB17, ZNF154, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF177, ZNF180, ZNF189, ZNF207, ZNF208, ZNF214, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZP3, ZXDA, PRDM2, LRP8, FZD5, AIMP2, MAFK, ARHGEF5, NUP214, FOSL1, FGF23, AAAS, ANP32A, SF3A2, ZNF239, DPF1, NRIP1, USP9X, RBM10, KDM5C, USP9Y, ARID1A, PICALM, EOMES, FZD4, FZD6, FZD7, FZD8, GFI1B, HIST1H2AK, HIST2H2AC, SOX14, UXT, ZNF282, NR0B2, UTF1, DUSP11, CUL3, CUL2, TTF2, KLF11, OGT, IKBKG, IKBKAP, HAT1, GAS7, PIR, FCN3, BLZF1, PRPF18, RRP1, KHSRP, PRKRA, STK16, RGS20, KLF7, TP63, RNASET2, CHRD, DDX3Y, DYNLL1, SRSF9, TRADD, EED, RIPK1, RIPK2, CREG1, SAP30, HESX1, PER3, TAX1BP1, BUD31, PHOX2B, FUBP3, HIST1H2AG, RPS6KA4, TNFSF18, TAF1B, TAF1A, UBA3, RPL14, USP2, PDLIM1, PRPF3, CBFA2T2, DYRK1B, CTDP1, SCAF11, ARHGEF2, DDX21, BMP15, CCPG1, RPS6KA5, ITGB1BP1, ZNF235, TRIP11, HMGN3, TRIP4, GTF3C5, GTF3C4, GTF3C3, EFTUD2, RPL23, COX5A, ZRANB2, SNRNP40, DDX23, HAND1, ZNF264, EIF2AK3, FHL5, ATG5, ONECUT2, LITAF, TBPL1, ZNF254, CIR1, GTPBP1, NR1D1, CLOCK, SOX13, RBM39, CREB5, RNF14, NUP155, PPM1F, ZNF516, SAFB2, PHF14, VGLL4, NUP93, BZW1, KIAA0391, DHX34, ST18, UTP14C, ZNF646, USP34, SETD1A, ZNF536, ZFYVE16, EIF4A3, DHX38, RNF40, RB1CC1, ARHGEF11, ZEB2, ZBTB24, ZNF518A, SMG7, RNF10, ZBTB5, RBM8A, NR1I3, NR1H4, NR1D2, DMTF1, CASP8AP2, NR2E3, ZBTB33, HDAC6, PDCD7, PQBP1, ZNF263, YAF2, G3BP1, SUGP2, ZNF197, ZNF256, RNF41, OLIG2, DENND4A, IRX5, RAMP3 |
1865 | GO:0044267 | 0.01 | 1.18 | 385.96 | 424 | 1427 | cellular protein metabolic process | ABCA1, ABCA3, ABO, ACP1, ACP2, ACTB, ACTL6A, ADAM10, ADD1, ADH5, ADPRH, ADRBK1, ANPEP, SLC25A4, ANXA1, APBB1, KLK3, ARCN1, TRIM23, ARF4, ARNTL, ARSA, STS, ARSD, ARSE, ARSF, ART1, ASL, ASNS, ATR, AXL, BACH1, BARD1, BCHE, OPN1SW, BCR, BHMT, BLK, BMX, BNIP3L, BRCA2, BTK, SLC25A20, CANX, CBL, CBLB, CCNF, CDK11B, CDK3, CDK6, CDK8, CHRM1, CHRM3, CHUK, TBCB, CLK1, CLK3, TPP1, COPA, COPB1, CREB1, CSNK1G3, SLC25A10, CTH, CTSG, CTSK, CTSS, DAD1, DARS, DDB1, DDX11, DHPS, DMBT1, DYNC1H1, DPH2, DTX1, E4F1, PHC2, EEF1B2, EGR2, EHHADH, EIF1AX, ELK1, ENPEP, EPHA3, EPHA5, EPHB2, EPHB3, EYA4, ERCC3, ERG, EVPL, EXT2, EXTL1, EXTL3, EYA2, EZH1, FANCF, FAP, FAU, EFEMP1, FKBP3, FKBP5, FSHB, FUT6, FUT8, FYB, GAD1, GARS, GATA6, OPN1MW, GFER, B4GALT1, GMDS, GOLGB1, GRIA1, GUCY2C, GUCY2F, GUCY2D, H3F3B, HARS, HDGF, HEXB, HLCS, HMBS, HNRNPC, HSF4, HSPA9, IAPP, IGFBP6, IL12RB2, INCENP, INSRR, ITGAV, EIF6, IVL, KCNH2, LIMK2, LIPE, SMAD9, MAN2B1, MDH2, MFGE8, MGAT2, MGAT3, ATXN3, CNOT4, NUP98, OXTR, P4HA1, PAH, PAM, PCBP2, PCK1, PCMT1, PCNA, PDK4, PEX12, CFP, PFDN2, PGA5, PHF2, PHKA2, PHKB, PHKG1, PPIB, PPID, PPM1B, PPP1R3C, PPP2CB, PPP4C, PPP6C, PPT1, PRKCB, PRKCI, PRKCQ, PRKCSH, PRKG1, PRKX, PRL, PSKH1, PTPN4, PTPN7, PTPN9, PTPN12, PTPN14, PTPRE, PTPRH, PTPRN, PTPRN2, PTPRS, QARS, RAB1A, RAB3B, RAB6A, RAB27A, RABGGTA, RABGGTB, RAD21, RAG2, RANBP2, RANGAP1, RBBP6, OPN1LW, RGR, RNF2, RNF6, RPL3, RPL3L, RPL5, RPL6, RPL10, RPL22, RPL23A, RPL24, RPL26, RPL28, RPL31, RPL34, RPL35A, RPL36AL, RPL37, RPL37A, RPL39, RPL36A, RPS3A, RPS4Y1, RPS6, RPS6KA2, RPS7, RPS11, RPS16, RPS19, RPS20, RPS26, RPS27, SALL1, SATB1, SBF1, ATXN7, TRAPPC2, SETMAR, SFPQ, SFTPB, SFTPD, SGK1, SHMT2, SLC34A1, SOX11, SP3, SP100, UAP1, SPRR2A, SPRR2D, SPRR2E, SPRR2G, SPRR3, SRP14, SRPK2, SSR3, STAT4, SULT1A3, TAF10, TBCD, TBCE, TBL1X, TOP1, TOP2A, TOP2B, NR2C2, TRIO, TTC3, TTF1, TUBA4A, TUFM, TYK2, TYRO3, UBA7, UBE2D2, UBE2E2, UBE2H, UBE2V1, UCP1, UFD1L, KDM6A, UTY, VBP1, VRK1, WRN, TRIM25, ZBTB17, PRDM2, PTP4A1, RNF103, TUBA1A, SCG2, TUSC3, NUP214, SLC25A16, AAAS, GAN, CLPP, USP11, USP9X, KDM5C, SMC1A, KDM5D, USP9Y, HIST1H4I, BAP1, HIST1H3A, HIST1H3I, HIST1H3J, HIST1H3B, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4J, HIST1H4C, HIST1H4B, HIST1H4E, HIST1H4L, DYRK2, DUSP11, CUL4A, CUL2, TPST2, TPST1, FKBP6, PPM1D, HAT1, COPS3, STK16, SLC25A12, RUVBL1, USO1, DDX3Y, DYNLL1, TNKS, GALNT4, B4GALT4, B4GALT3, B3GALT2, CTSF, RIOK3, DYRK4, CDKL1, DPM2, EIF2S2, HERC2, HIST1H3F, P4HA2, CDKL2, SLC25A14, RNF8, BAZ1B, UBA3, RPL14, USP6, USP2, USP8, ATP6V0D1, SMC3, DYRK1B, CTDP1, DCLK1, AURKB, STK17B, STK17A, COPB2, COPS2, GTF3C4, B4GALT6, RPL23, UBE4A, COG1, PICK1, PIGL, GOSR1, SEC22B, GTPBP1, GOSR2, NR1D1, CLOCK, BRE, CDC42BPB, RNF7, AATK, SNCAIP, NUP155, TTLL4, NUP93, UBE3C, VPRBP, USP34, SETD1A, TATDN2, TOMM20, SPOCK2, CUL7, DNAJC6, AREL1, KLHL21, RNF10, USP3, NR1H4, PDCD6IP, GNE, PIGK, PARP3, SH2D3C, SH2D3A, UBA2, SAE1, PTPRU, COL4A3BP, UST, SGK2, ABI2, TRIM28, CHST4, SLC25A13, SLC25A15, ZMPSTE24 |
1866 | GO:0003008 | 0.04 | 1.17 | 199.27 | 220 | 707 | system process | ABCA4, ABL1, ABL2, ACVRL1, ADCY1, ADCY7, ALDH1A3, AMPH, ANGPT1, APLP2, APP, ARF4, ARR3, STS, ALDH7A1, BBS4, BCHE, OPN1SW, BCR, BDKRB1, BMP4, CA6, CACNA1A, CD36, SCARB1, CDK5, CDKN2D, CHAT, TPP1, CNGA1, CNGA2, CNR1, COL1A1, COL2A1, COL4A3, COL11A1, COPA, CREB1, CRX, CRYBA1, CRYBA4, CRYGB, CST1, CTNS, CTNND2, CTSG, CX3CR1, CYP11B1, DBI, COCH, CYB5R3, DIAPH1, DLG2, DNM1, DPP6, DRD5, RCAN1, S1PR1, EGR2, EIF4EBP2, ELN, ENPEP, EPB41, EPHB1, EYA4, FABP7, EFEMP1, FEN1, AFF2, FYN, FZD2, GABRA5, GABRB2, GABRR2, GATA3, GCGR, OPN1MW, GJA3, GJB2, GLRB, GM2A, GNAS, GNAT1, GNAT2, GPI, FFAR3, GPX1, GRIA1, GRID2, GUCA1A, GUCY2F, GUCY2D, HAS2, HEXB, HOXC10, HOXD10, HPN, IAPP, ID2, IGF2, IL12B, IMPG1, ITGA5, ITGB1, JUN, KCNJ8, KCNJ10, KCNK2, KCNN4, KIT, MAN2B1, MEOX2, NRCAM, NTF4, NTRK2, OAT, OLR1, OMP, OPA1, OR1F1, OR2C1, P2RX7, PAX2, PAX3, PCSK5, SERPINF1, PENK, SERPINB6, PPT1, PRCP, PRKACB, PRKACG, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B, MAPK1, MAPK3, PTN, PTPRJ, PTPRZ1, RABGGTA, RABGGTB, RAC3, OPN1LW, RCVRN, PRPH2, RENBP, RGR, RLBP1, RP9, RPGR, RPL38, RPS6KA2, ACSM3, ATXN7, SCN1A, SCN2A, SCN8A, SCNN1A, SFRP5, SGCD, SIX3, SLC2A5, SLC6A4, SLC12A2, SNAP25, SOD2, SOX9, XCL2, CNTN2, TBL1X, HNF1A, ZNF354A, NR2E1, TULP1, TULP2, TYR, CLRN1, VDAC1, VDR, VEGFA, VIL1, WFS1, KCNAB1, TUSC3, FOSL1, AAAS, FZD4, FZD9, OR1A1, OR1D5, OR1G1, OR3A3, SOX14, CNTNAP1, KCNAB2, CYP4F2, AKR1C3, RGS9, TAAR5, UNC119, DGKI, ITGB1BP1, GPR52, SLIT2, NRXN3, NRXN1, NRXN2, ATG5, SLC4A7, RIN1, GUCA1C, FAM65B, EIF4A3, WDR1, NR2E3, ATP6AP2, RCAN2, RAMP3 |
1867 | GO:0044260 | 0.03 | 1.13 | 396.63 | 424 | 1520 | cellular macromolecule metabolic process | ABCA2, ACTN4, ACTN1, AEBP1, AES, NR0B1, AHR, ALX3, ANXA4, APBB2, ARF1, PHOX2A, ASCL1, ASCL2, RERE, BCL9, BICD1, PRDM1, BRDT, KLF9, KLF5, BTF3, BYSL, CAMLG, CAPN1, RUNX2, CD3D, CD9, CD86, TNFSF8, CD63, CDH1, CDX2, CEBPE, CENPB, CHD2, CHD4, CLNS1A, CLTC, CMKLR1, COL1A1, COL2A1, COL11A1, COX6A1, COX6B1, COX7B, COX7C, COX8A, CPS1, CRX, VCAN, CSTF3, CTNND1, CTNND2, DBP, DDX5, DHX8, DDX10, DHFR, DLX5, DNM1, DNM2, DRD3, ARID3A, ATN1, RCAN1, TSC22D3, E2F5, E2F6, EBF1, EDA, S1PR1, CELSR2, EGR3, EGR4, ELAVL2, ELF1, ELF3, ELK3, EMX1, EMX2, EN1, ERF, ESRRG, ETS1, ETS2, ETV1, ETV2, ETV3, ETV4, ETV5, ETV6, EVX1, EWSR1, FBN1, GPC4, GPC5, FOXD1, FLII, AFF2, NR5A2, FZD2, G6PC, GAA, GALR1, GATA4, GCGR, GDNF, GLO1, GPX2, GSC2, GTF2I, GTF3A, BRF1, GTF3C1, GTF3C2, GYS2, HIST1H1C, HIST1H1D, HIST1H1E, HIST1H2AD, HAS1, HAS2, HAS3, HBE1, HEXA, HIC1, HIVEP2, HLF, NR4A1, HMX2, FOXA2, HNF4G, ONECUT1, HOXC10, HOXC11, HOXD4, HOXD8, HOXD9, HOXD10, HOXD12, HSBP1, ID2, IDS, IDUA, SP110, IHH, ING2, INSIG1, ITGA6, IRF1, IRF5, JUNB, JUND, JUP, LCAT, LIPC, LMO1, MAZ, MEOX2, CIITA, AFF1, FOXO4, DRG1, NRF1, YBX1, OAS1, OAS3, OTX1, OTX2, OVOL1, PAX3, PAX9, CHMP1A, PDE8A, PEG3, PGR, PTCH1, PTGIS, PTH, PTMA, PURB, PYGB, PYGM, RAB5A, RARB, RBL2, RBMS2, DPF2, RFX1, RFX3, RFX4, RFXAP, RGS12, RHEB, RNASE1, RP9, RXRG, RYR2, S100A1, SDC1, SELE, SFRP5, SRSF1, SRSF5, SRSF7, SFSWAP, TRA2B, SIM2, SIX3, SLC9A1, SMARCA2, SMARCA4, SMARCD3, SMARCE1, SNAI1, SNAPC3, SNAPC4, SNRPA, SNRPA1, SNRPC, SNRPD1, SNRPE, SNRPF, SOD2, SOX3, SOX5, SOX10, SP1, SP2, SPIB, SRF, SRY, STAT2, STAT3, STAT5B, T, TAF4B, TAL1, TARBP1, TBP, HNF1A, GCFC2, ZNF354A, PRDX2, NR2F1, KLF10, NR2E1, TMPO, TNNI2, NR2C1, TRAF1, TRIP6, TULP3, SCGB1A1, USF1, VAV1, VDR, YWHAH, YWHAZ, ZFP37, ZFPL1, ZFX, ZIC1, ZNF3, ZNF7, CNBP, ZNF16, ZNF17, ZNF20, ZNF22, ZNF23, ZNF24, ZNF26, ZNF28, ZNF32, ZNF33B, ZNF35, ZKSCAN1, ZSCAN21, ZNF45, ZBTB25, ZNF70, ZNF74, ZNF75A, ZNF76, ZNF79, ZNF84, ZNF221, ZNF99, ZNF124, ZNF131, ZNF136, ZNF140, ZNF141, ZNF142, ZNF143, ZNF148, ZNF154, ZNF155, ZNF157, VEZF1, ZNF165, ZNF174, ZNF177, ZNF180, ZNF189, ZNF208, ZNF214, ZNF217, ZNF223, ZNF224, ZNF225, ZNF229, ZNF232, ZXDA, MAFK, FOSL1, ANP32A, SF3A2, ZNF239, DPF1, NRIP1, RBM10, ARID1A, EOMES, FZD6, HIST1H2AK, HIST2H2AC, SOX14, UXT, ZNF282, NR0B2, UTF1, TTF2, KLF11, GAS7, PIR, FCN3, BLZF1, RRP1, RGS20, KLF7, TP63, CHRD, SRSF9, CREG1, SAP30, HESX1, PER3, TAX1BP1, BUD31, PHOX2B, FUBP3, HIST1H2AG, MGAM, STBD1, TAF1B, TAF1A, PDLIM1, PRPF3, CBFA2T2, SCAF11, DDX21, RAB11B, CCPG1, ZNF235, TRIP11, HMGN3, TRIP4, GTF3C5, GTF3C3, EFTUD2, COX5A, ZRANB2, SNRNP40, DDX23, HAND1, ZNF264, FHL5, CHST3, ONECUT2, LITAF, TBPL1, ZNF254, CIR1, SOX13, RBM39, CREB5, ZNF516, SAFB2, SDC3, PHF14, VGLL4, BZW1, KIAA0391, ST18, UTP14C, ZNF646, ZNF536, ZFYVE16, DHX38, ARHGEF11, ZBTB24, ZNF518A, EPM2AIP1, ZBTB5, HS3ST3B1, NR1I3, NR1D2, DMTF1, NR2E3, ZBTB33, PDCD7, PQBP1, ZNF263, YAF2, SUGP2, ZNF197, ZNF256, OLIG2, DENND4A, IRX5, RAMP3 |